locus-tag	class	description
FFM81_000005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FFM81_000005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FFM81_000005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFM81_000025	COG0501	Belongs to the peptidase M48B family
FFM81_000045	COG2270	Major facilitator Superfamily
FFM81_000060	COG0288	reversible hydration of carbon dioxide
FFM81_000075	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FFM81_000085	COG1785	Belongs to the alkaline phosphatase family
FFM81_000095	COG1136	(ABC) transporter
FFM81_000110	COG0671	phosphoesterase, PA-phosphatase related
FFM81_000115	COG0473	3-isopropylmalate dehydrogenase activity
FFM81_000125	COG0066	3-isopropylmalate dehydratase activity
FFM81_000160	COG0587	DNA-directed DNA polymerase activity
FFM81_000175	COG0494	nUDIX hydrolase
FFM81_000185	COG0793	Belongs to the peptidase S41A family
FFM81_000195	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FFM81_000200	COG0799	negative regulation of ribosome biogenesis
FFM81_000210	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FFM81_000215	COG4149	molybdate abc transporter
FFM81_000220	COG0725	ABC transporter, periplasmic molybdate-binding protein
FFM81_000225	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FFM81_000230	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FFM81_000235	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FFM81_000240	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FFM81_000260	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FFM81_000265	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FFM81_000320	COG1129	ABC transporter
FFM81_000325	COG4211	Belongs to the binding-protein-dependent transport system permease family
FFM81_000340	COG0601	transmembrane transport
FFM81_000345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFM81_000350	COG0444	Belongs to the ABC transporter superfamily
FFM81_000385	COG1132	(ABC) transporter
FFM81_000395	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FFM81_000400	COG0431	NADPH-dependent FMN reductase
FFM81_000405	COG1126	abc transporter atp-binding protein
FFM81_000410	COG0765	amino acid transport
FFM81_000415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFM81_000425	COG1349	DNA-binding transcription factor activity
FFM81_000430	COG2223	nitrite transmembrane transporter activity
FFM81_000435	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FFM81_000440	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FFM81_000445	COG0142	geranyltranstransferase activity
FFM81_000450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FFM81_000465	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FFM81_000475	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
FFM81_000480	COG0183	Belongs to the thiolase family
FFM81_000505	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FFM81_000510	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FFM81_000515	COG1329	Transcriptional regulator
FFM81_000520	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FFM81_000545	COG0488	(ABC) transporter
FFM81_000555	COG4178	(ABC) transporter
FFM81_000560	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FFM81_000570	COG2188	Transcriptional regulator
FFM81_000575	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FFM81_000580	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FFM81_000585	COG4821	SIS domain
FFM81_000590	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FFM81_000600	COG1509	lysine 2,3-aminomutase activity
FFM81_000605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FFM81_000615	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FFM81_000640	COG0438	transferase activity, transferring glycosyl groups
FFM81_000655	COG5383	Protein conserved in bacteria
FFM81_000660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FFM81_000665	COG1012	belongs to the aldehyde dehydrogenase family
FFM81_000680	COG3842	ATPase activity
FFM81_000690	COG0405	Gamma-glutamyltransferase
FFM81_000730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFM81_000740	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_000750	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FFM81_000755	COG0517	IMP dehydrogenase activity
FFM81_000780	COG2835	tetraacyldisaccharide 4'-kinase activity
FFM81_000785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FFM81_000790	COG1946	Acyl-CoA thioesterase
FFM81_000795	COG0347	Belongs to the P(II) protein family
FFM81_000800	COG0004	ammonium transporteR
FFM81_000805	COG1674	ftsk spoiiie
FFM81_000810	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FFM81_000825	COG0745	RESPONSE REGULATOR receiver
FFM81_000835	COG0656	L-ascorbic acid biosynthetic process
FFM81_000845	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FFM81_000855	COG0765	amino acid transport
FFM81_000865	COG0335	large ribosomal subunit rRNA binding
FFM81_000870	COG0336	Belongs to the RNA methyltransferase TrmD family
FFM81_000875	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FFM81_000880	COG0228	four-way junction DNA binding
FFM81_000885	COG0287	Prephenate dehydrogenase
FFM81_000885	COG1605	Chorismate mutase
FFM81_000890	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FFM81_000900	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FFM81_000905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FFM81_000910	COG0552	protein localization to endoplasmic reticulum
FFM81_000915	COG2917	probably involved in intracellular septation
FFM81_000935	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FFM81_000940	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FFM81_000945	COG4133	protoheme IX ABC transporter activity
FFM81_000950	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FFM81_000970	COG0670	Belongs to the BI1 family
FFM81_000980	COG4181	ATPase activity
FFM81_000990	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FFM81_000995	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FFM81_001000	COG2154	pterin-4-alpha-carbinolamine dehydratase
FFM81_001010	COG1595	DNA-templated transcription, initiation
FFM81_001020	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FFM81_001030	COG4120	Belongs to the binding-protein-dependent transport system permease family
FFM81_001050	COG0137	argininosuccinate synthase activity
FFM81_001075	COG0583	DNA-binding transcription factor activity
FFM81_001085	COG1764	response to oxidative stress
FFM81_001105	COG0339	signal peptide processing
FFM81_001110	COG1217	gtp-binding protein TYPA
FFM81_001120	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FFM81_001125	COG1872	DUF167
FFM81_001165	COG0181	hydroxymethylbilane synthase activity
FFM81_001170	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FFM81_001175	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FFM81_001190	COG2264	protein methyltransferase activity
FFM81_001195	COG2423	ornithine cyclodeaminase activity
FFM81_001200	COG0765	amino acid transport
FFM81_001205	COG0765	amino acid transport
FFM81_001210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFM81_001230	COG4149	molybdate abc transporter
FFM81_001235	COG3842	ATPase activity
FFM81_001245	COG0251	oxidation-reduction process
FFM81_001280	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FFM81_001285	COG0039	L-malate dehydrogenase activity
FFM81_001290	COG0045	succinate-CoA ligase (ADP-forming) activity
FFM81_001300	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FFM81_001305	COG0567	Dehydrogenase, E1 component
FFM81_001315	COG0508	dehydrogenase complex catalyzes the overall conversion of
FFM81_001330	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_001345	COG4948	Mandelate Racemase Muconate Lactonizing
FFM81_001350	COG4948	Mandelate Racemase Muconate Lactonizing
FFM81_001365	COG1653	transport
FFM81_001380	COG3842	ATPase activity
FFM81_001385	COG4948	Mandelate Racemase Muconate Lactonizing
FFM81_001395	COG3038	cytochrome b561
FFM81_001405	COG4974	Belongs to the 'phage' integrase family
FFM81_001420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FFM81_001435	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FFM81_001440	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FFM81_001445	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FFM81_001450	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FFM81_001460	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FFM81_001475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FFM81_001480	COG1116	anion transmembrane transporter activity
FFM81_001485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FFM81_001500	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_001505	COG0640	Transcriptional regulator
FFM81_001510	COG0583	DNA-binding transcription factor activity
FFM81_001515	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FFM81_001525	COG3383	formate dehydrogenase (NAD+) activity
FFM81_001530	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FFM81_001550	COG0835	chemotaxis
FFM81_001555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FFM81_001560	COG0010	Belongs to the arginase family
FFM81_001575	COG0729	surface antigen
FFM81_001585	COG0156	8-amino-7-oxononanoate synthase activity
FFM81_001600	COG1175	transmembrane transport
FFM81_001605	COG0395	ABC-type sugar transport system, permease component
FFM81_001620	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FFM81_001675	COG1793	dna ligase
FFM81_001675	COG3285	dna ligase
FFM81_001715	COG1686	Belongs to the peptidase S11 family
FFM81_001720	COG0523	cobalamin synthesis protein
FFM81_001730	COG3034	peptidoglycan biosynthetic process
FFM81_001735	COG2207	Transcriptional regulator
FFM81_001740	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_001750	COG2207	Transcriptional regulator
FFM81_001760	COG0825	malonyl-CoA metabolic process
FFM81_001765	COG4974	Belongs to the 'phage' integrase family
FFM81_001775	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FFM81_001780	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FFM81_001785	COG4536	flavin adenine dinucleotide binding
FFM81_001815	COG0563	adenylate kinase activity
FFM81_001825	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FFM81_001845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFM81_001850	COG2226	methyltransferase
FFM81_001855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FFM81_001860	COG0287	Prephenate dehydrogenase
FFM81_001875	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FFM81_001895	COG2884	Cell division ATP-binding protein ftsE
FFM81_001930	COG0165	Argininosuccinate lyase
FFM81_001935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFM81_001940	COG1250	3-hydroxyacyl-CoA dehydrogenase
FFM81_001945	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FFM81_001950	COG2086	electron transfer activity
FFM81_001970	COG0300	oxidoreductase activity
FFM81_001980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FFM81_002010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FFM81_002010	COG4651	solute:proton antiporter activity
FFM81_002040	COG0667	Aldo Keto reductase
FFM81_002045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FFM81_002060	COG0653	protein targeting
FFM81_002065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FFM81_002070	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FFM81_002080	COG0494	nUDIX hydrolase
FFM81_002095	COG2226	methyltransferase
FFM81_002120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FFM81_002125	COG0527	aspartate kinase activity
FFM81_002135	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FFM81_002140	COG2890	protein-(glutamine-N5) methyltransferase activity
FFM81_002150	COG0542	response to heat
FFM81_002190	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FFM81_002195	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFM81_002220	COG0649	NAD binding
FFM81_002225	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFM81_002230	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFM81_002250	COG0651	ATP synthesis coupled electron transport
FFM81_002260	COG0651	ATP synthesis coupled electron transport
FFM81_002265	COG0713	ATP synthesis coupled electron transport
FFM81_002295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFM81_002305	COG0387	Pfam Sodium calcium exchanger
FFM81_002310	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_002320	COG0693	protein deglycase activity
FFM81_002330	COG1012	belongs to the aldehyde dehydrogenase family
FFM81_002345	COG0493	'glutamate synthase
FFM81_002345	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FFM81_002360	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FFM81_002365	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FFM81_002370	COG1780	Probably involved in ribonucleotide reductase function
FFM81_002380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FFM81_002390	COG0602	queuosine metabolic process
FFM81_002395	COG0720	synthase
FFM81_002400	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FFM81_002405	COG1609	Transcriptional regulator
FFM81_002410	COG1653	transport
FFM81_002415	COG1175	transmembrane transport
FFM81_002420	COG0395	ABC-type sugar transport system, permease component
FFM81_002425	COG3842	ATPase activity
FFM81_002435	COG3386	PFAM SMP-30 Gluconolaconase
FFM81_002440	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_002460	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_002470	COG4948	Mandelate Racemase Muconate Lactonizing
FFM81_002475	COG2186	Transcriptional regulator
FFM81_002485	COG1129	ABC transporter
FFM81_002500	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_002505	COG1764	response to oxidative stress
FFM81_002530	COG1940	carbohydrate kinase activity
FFM81_002540	COG2390	Transcriptional regulator
FFM81_002550	COG1175	transmembrane transport
FFM81_002620	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FFM81_002645	COG1177	transmembrane transport
FFM81_002650	COG1176	ABC-type spermidine putrescine transport system, permease component I
FFM81_002655	COG3842	ATPase activity
FFM81_002660	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FFM81_002665	COG0583	DNA-binding transcription factor activity
FFM81_002675	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FFM81_002680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FFM81_002685	COG1253	flavin adenine dinucleotide binding
FFM81_002710	COG1609	Transcriptional regulator
FFM81_002715	COG1070	Carbohydrate kinase
FFM81_002720	COG2115	Belongs to the xylose isomerase family
FFM81_002725	COG1609	Transcriptional regulator
FFM81_002730	COG1129	ABC transporter
FFM81_002735	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFM81_002740	COG1879	ABC-type sugar transport system periplasmic component
FFM81_002750	COG0673	inositol 2-dehydrogenase activity
FFM81_002770	COG1054	Belongs to the UPF0176 family
FFM81_002780	COG2954	triphosphatase activity
FFM81_002815	COG0583	DNA-binding transcription factor activity
FFM81_002850	COG0523	cobalamin synthesis protein
FFM81_002860	COG1846	Transcriptional regulator
FFM81_002865	COG1609	Transcriptional regulator
FFM81_002870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FFM81_002875	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FFM81_002880	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FFM81_002890	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FFM81_002895	COG5001	Diguanylate cyclase
FFM81_002930	COG2202	Pas domain
FFM81_002930	COG3920	Histidine kinase
FFM81_002940	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FFM81_002960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FFM81_002970	COG0446	pyridine nucleotide-disulphide oxidoreductase
FFM81_002970	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FFM81_002990	COG1523	belongs to the glycosyl hydrolase 13 family
FFM81_002995	COG0033	Phosphoglucomutase
FFM81_003000	COG0297	glycogen (starch) synthase activity
FFM81_003005	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FFM81_003010	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FFM81_003015	COG0058	SHG alpha-glucan phosphorylase activity
FFM81_003030	COG2308	Evidence 4 Homologs of previously reported genes of
FFM81_003030	COG2307	Protein conserved in bacteria
FFM81_003140	COG0071	Belongs to the small heat shock protein (HSP20) family
FFM81_003160	COG0067	glutamate synthase
FFM81_003160	COG0070	glutamate synthase
FFM81_003160	COG0069	glutamate synthase activity
FFM81_003175	COG2951	lytic endotransglycosylase activity
FFM81_003180	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FFM81_003190	COG0517	IMP dehydrogenase activity
FFM81_003190	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FFM81_003200	COG0330	HflC and HflK could
FFM81_003205	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FFM81_003210	COG0737	Belongs to the 5'-nucleotidase family
FFM81_003220	COG5310	Homospermidine synthase
FFM81_003245	COG2204	response regulator
FFM81_003250	COG3108	Peptidase M15
FFM81_003255	COG3750	Belongs to the UPF0335 family
FFM81_003275	COG0469	pyruvate kinase activity
FFM81_003280	COG1280	lysine exporter protein (LysE YggA)
FFM81_003295	COG1942	4-Oxalocrotonate Tautomerase
FFM81_003300	COG0583	DNA-binding transcription factor activity
FFM81_003325	COG0457	Tetratricopeptide repeat
FFM81_003330	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FFM81_003335	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FFM81_003340	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FFM81_003355	COG0640	Transcriptional regulator
FFM81_003380	COG0483	inositol monophosphate 1-phosphatase activity
FFM81_003395	COG4941	Belongs to the sigma-70 factor family
FFM81_003405	COG3422	double-strand break repair
FFM81_003415	COG1132	(ABC) transporter
FFM81_003420	COG0254	rRNA binding
FFM81_003445	COG0384	phenazine biosynthesis protein PhzF
FFM81_003450	COG3588	fructose-bisphosphate aldolase
FFM81_003455	COG0126	phosphoglycerate kinase activity
FFM81_003520	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FFM81_003525	COG0668	transmembrane transport
FFM81_003535	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FFM81_003535	COG0392	lysyltransferase activity
FFM81_003545	COG2318	DinB family
FFM81_003550	COG0494	nUDIX hydrolase
FFM81_003555	COG1408	metallophosphoesterase
FFM81_003560	COG2255	four-way junction helicase activity
FFM81_003565	COG0632	four-way junction helicase activity
FFM81_003580	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FFM81_003585	COG0840	transmembrane signaling receptor activity
FFM81_003590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFM81_003595	COG0217	transcriptional regulatory protein
FFM81_003615	COG1692	metallophosphoesterase
FFM81_003645	COG0824	Thioesterase
FFM81_003655	COG0848	biopolymer transport protein
FFM81_003665	COG0823	Involved in the tonB-independent uptake of proteins
FFM81_003670	COG2885	chlorophyll binding
FFM81_003680	COG0037	tRNA processing
FFM81_003685	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FFM81_003690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FFM81_003705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FFM81_003715	COG0482	sulfurtransferase activity
FFM81_003740	COG0559	Belongs to the binding-protein-dependent transport system permease family
FFM81_003750	COG0683	leucine binding
FFM81_003765	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FFM81_003770	COG5001	Diguanylate cyclase
FFM81_003770	COG3300	MHYT domain
FFM81_003795	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FFM81_003825	COG1473	amidohydrolase
FFM81_003830	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FFM81_003845	COG1177	transmembrane transport
FFM81_003850	COG1176	ABC-type spermidine putrescine transport system, permease component I
FFM81_003870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FFM81_003880	COG1309	transcriptional regulator
FFM81_003885	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FFM81_003890	COG3273	potassium ion transport
FFM81_003890	COG0471	metal ion transport
FFM81_003895	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FFM81_003945	COG0668	transmembrane transport
FFM81_003955	COG0628	permease
FFM81_003970	COG1566	PFAM secretion protein HlyD family protein
FFM81_004000	COG2954	triphosphatase activity
FFM81_004025	COG2235	arginine
FFM81_004040	COG0531	amino acid
FFM81_004055	COG1982	Orn Lys Arg decarboxylase major
FFM81_004060	COG0531	amino acid
FFM81_004080	COG0387	Pfam Sodium calcium exchanger
FFM81_004100	COG2354	Protein conserved in bacteria
FFM81_004110	COG4993	Dehydrogenase
FFM81_004155	COG1596	polysaccharide export
FFM81_004165	COG0489	protein tyrosine kinase activity
FFM81_004185	COG0438	transferase activity, transferring glycosyl groups
FFM81_004190	COG2244	polysaccharide biosynthetic process
FFM81_004225	COG1653	transport
FFM81_004230	COG1846	Transcriptional regulator
FFM81_004230	COG1940	carbohydrate kinase activity
FFM81_004235	COG1653	transport
FFM81_004240	COG1175	transmembrane transport
FFM81_004250	COG3842	ATPase activity
FFM81_004265	COG3622	Belongs to the hyi family
FFM81_004270	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_004275	COG1959	2 iron, 2 sulfur cluster binding
FFM81_004285	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FFM81_004295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFM81_004320	COG2094	Belongs to the DNA glycosylase MPG family
FFM81_004335	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_004345	COG0657	acetylesterase activity
FFM81_004360	COG2084	Dehydrogenase
FFM81_004365	COG0129	dihydroxy-acid dehydratase activity
FFM81_004390	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FFM81_004400	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FFM81_004405	COG0564	pseudouridine synthase activity
FFM81_004475	COG0559	Belongs to the binding-protein-dependent transport system permease family
FFM81_004500	COG0683	leucine binding
FFM81_004510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFM81_004510	COG2205	protein histidine kinase activity
FFM81_004555	COG0831	urea catabolic process
FFM81_004560	COG3813	Protein conserved in bacteria
FFM81_004565	COG0832	Belongs to the urease beta subunit family
FFM81_004570	COG3755	Protein conserved in bacteria
FFM81_004575	COG1442	glycosyl transferase family 8
FFM81_004580	COG0804	urea catabolic process
FFM81_004590	COG3706	GGDEF domain
FFM81_004595	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FFM81_004600	COG0830	nickel cation binding
FFM81_004605	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FFM81_004620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FFM81_004625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FFM81_004630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FFM81_004660	COG1309	transcriptional regulator
FFM81_004665	COG4251	negative regulation of phosphorylation
FFM81_004675	COG0583	DNA-binding transcription factor activity
FFM81_004700	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FFM81_004725	COG0784	Response regulator, receiver
FFM81_004750	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FFM81_004755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFM81_004760	COG4558	Periplasmic binding protein
FFM81_004765	COG3720	iron ion transport
FFM81_004810	COG2346	COG2346, Truncated hemoglobins
FFM81_004820	COG2076	Multidrug Resistance protein
FFM81_004830	COG0673	inositol 2-dehydrogenase activity
FFM81_004845	COG0842	Transport permease protein
FFM81_004850	COG0842	Transport permease protein
FFM81_004855	COG1131	(ABC) transporter
FFM81_004860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFM81_004865	COG1309	transcriptional regulator
FFM81_004880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFM81_004895	COG0662	Cupin 2, conserved barrel domain protein
FFM81_004895	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FFM81_004905	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FFM81_004910	COG0346	lactoylglutathione lyase activity
FFM81_004915	COG0400	carboxylic ester hydrolase activity
FFM81_004930	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FFM81_004955	COG3206	protein involved in exopolysaccharide biosynthesis
FFM81_004955	COG0489	protein tyrosine kinase activity
FFM81_004975	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FFM81_004980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFM81_005005	COG1215	transferase activity, transferring glycosyl groups
FFM81_005010	COG0463	Glycosyl transferase, family 2
FFM81_005065	COG1396	sequence-specific DNA binding
FFM81_005095	COG1215	transferase activity, transferring glycosyl groups
FFM81_005100	COG1132	(ABC) transporter
FFM81_005105	COG1216	Glycosyl transferase, family 2
FFM81_005105	COG0463	Glycosyl transferase, family 2
FFM81_005110	COG1216	Glycosyl transferase, family 2
FFM81_005120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFM81_005145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFM81_005150	COG1129	ABC transporter
FFM81_005155	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFM81_005185	COG2072	flavoprotein involved in K transport
FFM81_005190	COG1126	abc transporter atp-binding protein
FFM81_005195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFM81_005200	COG0765	amino acid transport
FFM81_005205	COG0765	amino acid transport
FFM81_005220	COG0723	plastoquinol--plastocyanin reductase activity
FFM81_005235	COG3108	Peptidase M15
FFM81_005245	COG0495	leucyl-tRNA aminoacylation
FFM81_005285	COG1129	ABC transporter
FFM81_005290	COG4214	carbohydrate transport
FFM81_005295	COG4213	ABC transporter substrate-binding protein
FFM81_005305	COG0673	inositol 2-dehydrogenase activity
FFM81_005335	COG4214	carbohydrate transport
FFM81_005345	COG1012	belongs to the aldehyde dehydrogenase family
FFM81_005350	COG0129	dihydroxy-acid dehydratase activity
FFM81_005370	COG2308	Evidence 4 Homologs of previously reported genes of
FFM81_005380	COG0513	Belongs to the DEAD box helicase family
FFM81_005385	COG4335	DNA alkylation repair
FFM81_005390	COG1609	Transcriptional regulator
FFM81_005395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FFM81_005400	COG2814	Major facilitator Superfamily
FFM81_005410	COG0784	Response regulator, receiver
FFM81_005410	COG5002	protein histidine kinase activity
FFM81_005410	COG2205	protein histidine kinase activity
FFM81_005415	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FFM81_005415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FFM81_005420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FFM81_005435	COG3195	allantoin biosynthetic process
FFM81_005435	COG3648	Uricase
FFM81_005445	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FFM81_005450	COG2351	hydroxyisourate hydrolase activity
FFM81_005460	COG2268	Band 7 protein
FFM81_005475	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FFM81_005480	COG2267	carboxylic ester hydrolase activity
FFM81_005485	COG2453	phosphatase
FFM81_005485	COG0671	phosphoesterase, PA-phosphatase related
FFM81_005500	COG0402	S-adenosylhomocysteine deaminase activity
FFM81_005520	COG0583	DNA-binding transcription factor activity
FFM81_005535	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FFM81_005545	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_005550	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FFM81_005560	COG3795	YCII-related domain
FFM81_005565	COG4941	Belongs to the sigma-70 factor family
FFM81_005585	COG0024	Methionine aminopeptidase
FFM81_005595	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FFM81_005615	COG1160	GTP binding
FFM81_005645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFM81_005655	COG4608	Belongs to the ABC transporter superfamily
FFM81_005665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFM81_005670	COG0601	transmembrane transport
FFM81_005680	COG0366	Alpha amylase catalytic
FFM81_005685	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FFM81_005700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FFM81_005715	COG4175	Glycine betaine
FFM81_005730	COG1435	thymidine kinase activity
FFM81_005760	COG2862	Uncharacterized protein family, UPF0114
FFM81_005765	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FFM81_005780	COG4771	TonB-dependent receptor
FFM81_005780	COG1629	transport
FFM81_005785	COG0512	Glutamine amidotransferase of anthranilate synthase
FFM81_005785	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FFM81_005800	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FFM81_005805	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FFM81_005810	COG3416	Protein conserved in bacteria
FFM81_005815	COG0740	serine-type endopeptidase activity
FFM81_005820	COG3135	benzoate transporter
FFM81_005825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FFM81_005860	COG0435	Glutathione S-transferase
FFM81_005870	COG0454	-acetyltransferase
FFM81_005890	COG0714	Associated with various cellular activities
FFM81_005905	COG0617	tRNA 3'-terminal CCA addition
FFM81_005920	COG0408	coproporphyrinogen oxidase activity
FFM81_005930	COG1283	sodium-dependent phosphate transmembrane transporter activity
FFM81_005935	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FFM81_005940	COG1132	(ABC) transporter
FFM81_005950	COG1132	(ABC) transporter
FFM81_005970	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FFM81_005970	COG2857	Cytochrome c1
FFM81_005975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FFM81_006000	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FFM81_006010	COG0193	aminoacyl-tRNA hydrolase activity
FFM81_006020	COG3300	MHYT domain
FFM81_006020	COG5001	Diguanylate cyclase
FFM81_006025	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FFM81_006035	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FFM81_006060	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FFM81_006085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FFM81_006090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFM81_006110	COG1846	Transcriptional regulator
FFM81_006115	COG0745	RESPONSE REGULATOR receiver
FFM81_006125	COG1733	regulation of RNA biosynthetic process
FFM81_006140	COG1278	Cold shock
FFM81_006155	COG2133	pyrroloquinoline quinone binding
FFM81_006180	COG1442	glycosyl transferase family 8
FFM81_006195	COG0387	Pfam Sodium calcium exchanger
FFM81_006205	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FFM81_006210	COG0583	DNA-binding transcription factor activity
FFM81_006225	COG1902	pentaerythritol trinitrate reductase activity
FFM81_006230	COG2814	Major facilitator Superfamily
FFM81_006240	COG0583	DNA-binding transcription factor activity
FFM81_006245	COG0492	ferredoxin-NADP+ reductase activity
FFM81_006250	COG1522	sequence-specific DNA binding
FFM81_006255	COG2204	response regulator
FFM81_006260	COG4191	Histidine kinase
FFM81_006265	COG1301	dicarboxylic acid transport
FFM81_006275	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FFM81_006290	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FFM81_006300	COG2321	neutral zinc metallopeptidase
FFM81_006305	COG0667	Aldo Keto reductase
FFM81_006315	COG0534	Mate efflux family protein
FFM81_006325	COG0505	Belongs to the CarA family
FFM81_006340	COG0358	DNA primase activity
FFM81_006350	COG0156	8-amino-7-oxononanoate synthase activity
FFM81_006355	COG1063	alcohol dehydrogenase
FFM81_006370	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FFM81_006400	COG1917	Cupin 2, conserved barrel domain protein
FFM81_006400	COG2207	Transcriptional regulator
FFM81_006445	COG5507	3-demethylubiquinone-9 3-methyltransferase
FFM81_006450	COG0432	Pfam Uncharacterised protein family UPF0047
FFM81_006470	COG2968	Membrane
FFM81_006525	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FFM81_006540	COG2197	response regulator
FFM81_006590	COG3842	ATPase activity
FFM81_006600	COG1176	ABC-type spermidine putrescine transport system, permease component I
FFM81_006605	COG0395	ABC-type sugar transport system, permease component
FFM81_006615	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FFM81_006620	COG4702	Belongs to the UPF0303 family
FFM81_006640	COG2188	Transcriptional regulator
FFM81_006645	COG2971	BadF BadG BcrA BcrD
FFM81_006655	COG1175	transmembrane transport
FFM81_006660	COG0395	ABC-type sugar transport system, permease component
FFM81_006665	COG0673	inositol 2-dehydrogenase activity
FFM81_006675	COG3938	Belongs to the proline racemase family
FFM81_006680	COG3842	ATPase activity
FFM81_006685	COG2011	ABC-type metal ion transport system permease component
FFM81_006715	COG0174	glutamine synthetase
FFM81_006730	COG1192	Involved in chromosome partitioning
FFM81_006740	COG1376	ErfK ybiS ycfS ynhG family protein
FFM81_006755	COG0251	oxidation-reduction process
FFM81_006760	COG0028	Belongs to the TPP enzyme family
FFM81_006765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FFM81_006770	COG0697	spore germination
FFM81_006795	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FFM81_006810	COG3757	hydrolase, family 25
FFM81_006835	COG1280	lysine exporter protein (LysE YggA)
FFM81_006845	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FFM81_006850	COG3023	N-Acetylmuramoyl-L-alanine amidase
FFM81_006870	COG2001	Belongs to the MraZ family
FFM81_006875	COG0275	rRNA processing
FFM81_006890	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FFM81_006900	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FFM81_006905	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FFM81_006915	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FFM81_006920	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FFM81_006925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FFM81_006935	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FFM81_006940	COG1181	Belongs to the D-alanine--D-alanine ligase family
FFM81_006945	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FFM81_006950	COG0849	cell division
FFM81_006955	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FFM81_006965	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FFM81_006985	COG0456	acetyltransferase
FFM81_007000	COG0835	chemotaxis
FFM81_007005	COG1999	signal sequence binding
FFM81_007010	COG2264	protein methyltransferase activity
FFM81_007020	COG0006	proline dipeptidase activity
FFM81_007045	COG1335	isochorismatase
FFM81_007070	COG2766	serine protein kinase
FFM81_007075	COG2718	Belongs to the UPF0229 family
FFM81_007080	COG2719	SpoVR family
FFM81_007095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FFM81_007100	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FFM81_007105	COG2885	chlorophyll binding
FFM81_007120	COG3180	Ammonia monooxygenase
FFM81_007125	COG0583	DNA-binding transcription factor activity
FFM81_007130	COG0667	Aldo Keto reductase
FFM81_007135	COG0277	FAD linked oxidase domain protein
FFM81_007165	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FFM81_007175	COG0330	HflC and HflK could
FFM81_007180	COG0330	HflC and HflK could
FFM81_007190	COG0560	Phosphoserine phosphatase
FFM81_007195	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FFM81_007210	COG0028	Belongs to the TPP enzyme family
FFM81_007220	COG0656	L-ascorbic acid biosynthetic process
FFM81_007280	COG0668	transmembrane transport
FFM81_007300	COG0583	DNA-binding transcription factor activity
FFM81_007305	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FFM81_007320	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FFM81_007330	COG1733	regulation of RNA biosynthetic process
FFM81_007335	COG2814	Major facilitator Superfamily
FFM81_007340	COG1309	transcriptional regulator
FFM81_007345	COG0456	acetyltransferase
FFM81_007345	COG1846	Transcriptional regulator
FFM81_007350	COG1794	racemase activity, acting on amino acids and derivatives
FFM81_007355	COG1522	sequence-specific DNA binding
FFM81_007365	COG1252	NADH dehydrogenase
FFM81_007375	COG1064	alcohol dehydrogenase
FFM81_007380	COG2207	Transcriptional regulator
FFM81_007385	COG0463	Glycosyl transferase, family 2
FFM81_007410	COG1175	transmembrane transport
FFM81_007425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FFM81_007430	COG1069	ribulokinase activity
FFM81_007445	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FFM81_007465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FFM81_007470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFM81_007475	COG5634	Uncharacterized conserved protein (DUF2278)
FFM81_007480	COG0667	Aldo Keto reductase
FFM81_007485	COG1846	Transcriptional regulator
FFM81_007510	COG0384	phenazine biosynthesis protein PhzF
FFM81_007545	COG1253	flavin adenine dinucleotide binding
FFM81_007565	COG0523	cobalamin synthesis protein
FFM81_007575	COG1121	(ABC) transporter
FFM81_007580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FFM81_007635	COG0583	DNA-binding transcription factor activity
FFM81_007660	COG2329	Antibiotic biosynthesis monooxygenase
FFM81_007725	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FFM81_007735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFM81_007740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFM81_007745	COG1120	ATPase activity
FFM81_007765	COG0583	DNA-binding transcription factor activity
FFM81_007780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFM81_007785	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FFM81_007815	COG1214	PFAM Peptidase M22, glycoprotease
FFM81_007815	COG0456	acetyltransferase
FFM81_007820	COG5002	protein histidine kinase activity
FFM81_007825	COG2204	response regulator
FFM81_007830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFM81_007835	COG0697	spore germination
FFM81_007850	COG1846	Transcriptional regulator
FFM81_007850	COG1940	carbohydrate kinase activity
FFM81_007865	COG0395	ABC-type sugar transport system, permease component
FFM81_007960	COG3300	MHYT domain
FFM81_007960	COG5001	Diguanylate cyclase
FFM81_008035	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FFM81_008060	COG3453	Protein conserved in bacteria
FFM81_008060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFM81_008070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFM81_008075	COG1120	ATPase activity
FFM81_008100	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FFM81_008105	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FFM81_008110	COG1845	cytochrome c oxidase, subunit III
FFM81_008130	COG1917	Cupin 2, conserved barrel domain protein
FFM81_008130	COG2207	Transcriptional regulator
FFM81_008135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFM81_008140	COG1136	(ABC) transporter
FFM81_008175	COG0025	NhaP-type Na H and K H
FFM81_008180	COG3158	transport of potassium into the cell
FFM81_008185	COG0738	Major facilitator superfamily
FFM81_008195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FFM81_008205	COG0454	-acetyltransferase
FFM81_008205	COG0456	acetyltransferase
FFM81_008215	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FFM81_008235	COG0406	alpha-ribazole phosphatase activity
FFM81_008265	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FFM81_008305	COG1129	ABC transporter
FFM81_008305	COG0842	Transport permease protein
FFM81_008310	COG0431	NADPH-dependent FMN reductase
FFM81_008345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FFM81_008350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FFM81_008385	COG0556	nucleotide-excision repair
FFM81_008410	COG3152	Membrane
FFM81_008435	COG0784	Response regulator, receiver
FFM81_008440	COG0659	secondary active sulfate transmembrane transporter activity
FFM81_008455	COG0702	epimerase
FFM81_008490	COG1607	acyl-coa hydrolase
FFM81_008515	COG1764	response to oxidative stress
FFM81_008525	COG0494	nUDIX hydrolase
FFM81_008530	COG1846	Transcriptional regulator
FFM81_008540	COG0596	Alpha beta hydrolase
FFM81_008555	COG2376	Dihydroxyacetone kinase
FFM81_008575	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FFM81_008580	COG1461	Dihydroxyacetone kinase
FFM81_008590	COG3842	ATPase activity
FFM81_008605	COG0395	ABC-type sugar transport system, permease component
FFM81_008610	COG1175	transmembrane transport
FFM81_008620	COG2814	Major facilitator Superfamily
FFM81_008625	COG0745	RESPONSE REGULATOR receiver
FFM81_008635	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FFM81_008635	COG3264	Mechanosensitive ion channel
FFM81_008660	COG0745	RESPONSE REGULATOR receiver
FFM81_008700	COG1285	pathogenesis
FFM81_008705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FFM81_008715	COG0583	DNA-binding transcription factor activity
FFM81_008725	COG0583	DNA-binding transcription factor activity
FFM81_008745	COG1492	cobalamin metabolic process
FFM81_008750	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_008845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FFM81_008850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FFM81_008860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FFM81_008895	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FFM81_008905	COG3153	acetyltransferase
FFM81_008945	COG1175	transmembrane transport
FFM81_008950	COG0395	ABC-type sugar transport system, permease component
FFM81_008970	COG0673	inositol 2-dehydrogenase activity
FFM81_008975	COG0667	Aldo Keto reductase
FFM81_008980	COG3507	Belongs to the glycosyl hydrolase 43 family
FFM81_008985	COG1131	(ABC) transporter
FFM81_008990	COG0842	Transport permease protein
FFM81_008995	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_009020	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FFM81_009025	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FFM81_009035	COG2202	Pas domain
FFM81_009035	COG2205	protein histidine kinase activity
FFM81_009045	COG1573	uracil-dna glycosylase
FFM81_009050	COG1522	sequence-specific DNA binding
FFM81_009060	COG0583	DNA-binding transcription factor activity
FFM81_009070	COG2084	Dehydrogenase
FFM81_009080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FFM81_009085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FFM81_009090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFM81_009095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FFM81_009100	COG1116	anion transmembrane transporter activity
FFM81_009130	COG0640	Transcriptional regulator
FFM81_009150	COG5425	PFAM Usg family protein
FFM81_009165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFM81_009175	COG0596	Alpha beta hydrolase
FFM81_009185	COG0596	Alpha beta hydrolase
FFM81_009195	COG2205	protein histidine kinase activity
FFM81_009200	COG1764	response to oxidative stress
FFM81_009215	COG0640	Transcriptional regulator
FFM81_009225	COG0740	serine-type endopeptidase activity
FFM81_009230	COG0667	Aldo Keto reductase
FFM81_009245	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FFM81_009255	COG1763	Mo-molybdopterin cofactor biosynthetic process
FFM81_009260	COG0746	molybdenum cofactor guanylyltransferase activity
FFM81_009280	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_009285	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_009290	COG1129	ABC transporter
FFM81_009295	COG1879	ABC-type sugar transport system periplasmic component
FFM81_009300	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFM81_009305	COG3959	Transketolase, thiamine diphosphate binding domain
FFM81_009310	COG3958	Transketolase
FFM81_009315	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FFM81_009320	COG2390	Transcriptional regulator
FFM81_009325	COG1120	ATPase activity
FFM81_009330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFM81_009340	COG2226	methyltransferase
FFM81_009345	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FFM81_009360	COG1846	Transcriptional regulator
FFM81_009375	COG3706	GGDEF domain
FFM81_009385	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FFM81_009385	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FFM81_009395	COG0114	fumarate hydratase activity
FFM81_009400	COG2989	Protein conserved in bacteria
FFM81_009405	COG0546	phosphoglycolate phosphatase activity
FFM81_009410	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FFM81_009420	COG1254	Belongs to the acylphosphatase family
FFM81_009440	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FFM81_009445	COG1132	(ABC) transporter
FFM81_009470	COG0823	Involved in the tonB-independent uptake of proteins
FFM81_009490	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FFM81_009500	COG0840	transmembrane signaling receptor activity
FFM81_009505	COG0477	Major facilitator Superfamily
FFM81_009510	COG0778	Nitroreductase
FFM81_009520	COG0328	RNA-DNA hybrid ribonuclease activity
FFM81_009525	COG0280	phosphate acetyltransferase
FFM81_009525	COG0281	malic enzyme
FFM81_009540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFM81_009550	COG0588	phosphoglycerate mutase activity
FFM81_009560	COG2814	Major facilitator Superfamily
FFM81_009565	COG4948	Mandelate Racemase Muconate Lactonizing
FFM81_009575	COG1127	ABC transporter
FFM81_009595	COG1686	Belongs to the peptidase S11 family
FFM81_009605	COG1335	isochorismatase
FFM81_009620	COG0633	Ferredoxin
FFM81_009630	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FFM81_009640	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FFM81_009650	COG3768	UPF0283 membrane protein
FFM81_009655	COG3106	COG3106 Predicted ATPase
FFM81_009685	COG2313	pseudouridylate synthase activity
FFM81_009690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFM81_009695	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FFM81_009700	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FFM81_009735	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FFM81_009740	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FFM81_009750	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FFM81_009755	COG2066	Belongs to the glutaminase family
FFM81_009760	COG0037	tRNA processing
FFM81_009765	COG0483	inositol monophosphate 1-phosphatase activity
FFM81_009770	COG0483	inositol monophosphate 1-phosphatase activity
FFM81_009780	COG2814	Major facilitator Superfamily
FFM81_009785	COG2814	Major facilitator Superfamily
FFM81_009820	COG3971	2-oxopent-4-enoate hydratase activity
FFM81_009825	COG3485	protocatechuate 3,4-dioxygenase
FFM81_009845	COG0765	amino acid transport
FFM81_009850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFM81_009855	COG1126	abc transporter atp-binding protein
FFM81_009860	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FFM81_009870	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FFM81_009880	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FFM81_009890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFM81_009905	COG0047	phosphoribosylformylglycinamidine synthase activity
FFM81_009915	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FFM81_009920	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FFM81_009945	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FFM81_009970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FFM81_009985	COG0513	Belongs to the DEAD box helicase family
FFM81_009990	COG0741	lytic transglycosylase activity
FFM81_009990	COG0739	heme binding
FFM81_009990	COG1196	nuclear chromosome segregation
FFM81_009995	COG2833	Protein of unknown function (DUF455)
FFM81_010000	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FFM81_010015	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FFM81_010020	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FFM81_010035	COG2945	thiolester hydrolase activity
FFM81_010040	COG1104	cysteine desulfurase activity
FFM81_010045	COG0719	Fe-S assembly protein
FFM81_010050	COG0396	ATPase activity
FFM81_010055	COG0719	Fe-S assembly protein
FFM81_010060	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FFM81_010065	COG2151	metal-sulfur cluster biosynthetic enzyme
FFM81_010070	COG0316	Belongs to the HesB IscA family
FFM81_010080	COG1126	abc transporter atp-binding protein
FFM81_010090	COG0765	amino acid transport
FFM81_010105	COG0583	DNA-binding transcription factor activity
FFM81_010120	COG0436	Aminotransferase
FFM81_010135	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FFM81_010135	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FFM81_010140	COG0509	glycine decarboxylation via glycine cleavage system
FFM81_010145	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FFM81_010165	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FFM81_010170	COG0564	pseudouridine synthase activity
FFM81_010175	COG0546	phosphoglycolate phosphatase activity
FFM81_010190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FFM81_010195	COG2259	Doxx family
FFM81_010205	COG1671	Belongs to the UPF0178 family
FFM81_010210	COG2153	protein acetylation
FFM81_010215	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FFM81_010220	COG4770	biotin carboxylase activity
FFM81_010240	COG0321	lipoyl(octanoyl) transferase activity
FFM81_010260	COG0242	peptide deformylase activity
FFM81_010265	COG2239	Acts as a magnesium transporter
FFM81_010285	COG1760	l-serine dehydratase
FFM81_010300	COG1686	Belongs to the peptidase S11 family
FFM81_010335	COG1752	Esterase of the alpha-beta hydrolase superfamily
FFM81_010340	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FFM81_010345	COG0302	gtp cyclohydrolase
FFM81_010355	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FFM81_010365	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FFM81_010400	COG0628	permease
FFM81_010410	COG0187	DNA topoisomerase II activity
FFM81_010420	COG0149	triose-phosphate isomerase activity
FFM81_010430	COG0504	CTP synthase activity
FFM81_010440	COG0372	Belongs to the citrate synthase family
FFM81_010445	COG0372	Belongs to the citrate synthase family
FFM81_010460	COG0513	Belongs to the DEAD box helicase family
FFM81_010470	COG0303	'Molybdopterin
FFM81_010475	COG0315	cyclic pyranopterin monophosphate synthase activity
FFM81_010480	COG0134	indole-3-glycerol-phosphate synthase activity
FFM81_010485	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FFM81_010520	COG2824	Alkylphosphonate utilization operon protein PhnA
FFM81_010535	COG0583	DNA-binding transcription factor activity
FFM81_010565	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FFM81_010575	COG0730	response to heat
FFM81_010580	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FFM81_010585	COG0084	hydrolase, TatD family'
FFM81_010590	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FFM81_010590	COG0321	lipoyl(octanoyl) transferase activity
FFM81_010595	COG0861	Integral membrane protein TerC family
FFM81_010625	COG0668	transmembrane transport
FFM81_010635	COG5001	Diguanylate cyclase
FFM81_010635	COG3300	MHYT domain
FFM81_010665	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_010670	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FFM81_010680	COG2814	Major facilitator Superfamily
FFM81_010705	COG1609	Transcriptional regulator
FFM81_010720	COG1175	transmembrane transport
FFM81_010760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FFM81_010775	COG0343	queuine tRNA-ribosyltransferase activity
FFM81_010780	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FFM81_010795	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FFM81_010810	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FFM81_010815	COG2095	MarC family integral membrane protein
FFM81_010820	COG0629	single-stranded DNA binding
FFM81_010825	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FFM81_010840	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FFM81_010840	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FFM81_010845	COG0347	Belongs to the P(II) protein family
FFM81_010850	COG0174	glutamine synthetase
FFM81_010865	COG4166	transmembrane transport
FFM81_010885	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FFM81_010895	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FFM81_010905	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FFM81_010910	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FFM81_010915	COG2186	Transcriptional regulator
FFM81_010920	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFM81_010925	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFM81_010930	COG1129	ABC transporter
FFM81_010935	COG1879	ABC-type sugar transport system periplasmic component
FFM81_010945	COG1079	Belongs to the binding-protein-dependent transport system permease family
FFM81_010955	COG3845	ABC transporter
FFM81_010965	COG1183	phosphatidylcholine synthase activity
FFM81_010980	COG1136	(ABC) transporter
FFM81_010980	COG0577	efflux transmembrane transporter activity
FFM81_010985	COG0577	efflux transmembrane transporter activity
FFM81_010985	COG1136	(ABC) transporter
FFM81_011015	COG0395	ABC-type sugar transport system, permease component
FFM81_011020	COG1175	transmembrane transport
FFM81_011035	COG1609	Transcriptional regulator
FFM81_011045	COG0444	Belongs to the ABC transporter superfamily
FFM81_011055	COG0601	transmembrane transport
FFM81_011065	COG2186	Transcriptional regulator
FFM81_011070	COG1312	Catalyzes the dehydration of D-mannonate
FFM81_011075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FFM81_011080	COG3842	ATPase activity
FFM81_011085	COG0395	ABC-type sugar transport system, permease component
FFM81_011090	COG1175	transmembrane transport
FFM81_011095	COG1653	transport
FFM81_011180	COG3237	CsbD-like
FFM81_011195	COG0785	Cytochrome C biogenesis protein
FFM81_011200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFM81_011205	COG0679	Auxin Efflux Carrier
FFM81_011210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FFM81_011240	COG3956	TIGRFAM MazG family protein
FFM81_011245	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FFM81_011250	COG1923	regulation of RNA biosynthetic process
FFM81_011255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FFM81_011260	COG2204	response regulator
FFM81_011265	COG5000	phosphorelay sensor kinase activity
FFM81_011270	COG0667	Aldo Keto reductase
FFM81_011275	COG2204	response regulator
FFM81_011290	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FFM81_011290	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FFM81_011295	COG1058	Belongs to the CinA family
FFM81_011295	COG1546	Belongs to the CinA family
FFM81_011300	COG2867	negative regulation of translational initiation
FFM81_011310	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FFM81_011325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FFM81_011340	COG0508	dehydrogenase complex catalyzes the overall conversion of
FFM81_011345	COG0508	dehydrogenase complex catalyzes the overall conversion of
FFM81_011345	COG0022	dehydrogenase e1 component
FFM81_011350	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FFM81_011360	COG0148	phosphopyruvate hydratase activity
FFM81_011365	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FFM81_011375	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FFM81_011380	COG2333	competence protein COMEC
FFM81_011380	COG0658	competence protein
FFM81_011390	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FFM81_011395	COG3494	Protein of unknown function (DUF1009)
FFM81_011400	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FFM81_011405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FFM81_011410	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FFM81_011420	COG0750	zinc metalloprotease
FFM81_011430	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FFM81_011435	COG0233	cytoplasmic translational termination
FFM81_011440	COG0528	UMP kinase activity
FFM81_011445	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FFM81_011450	COG0052	Belongs to the universal ribosomal protein uS2 family
FFM81_011475	COG0537	adenosine 5'-monophosphoramidase activity
FFM81_011485	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FFM81_011505	COG2267	carboxylic ester hydrolase activity
FFM81_011520	COG0626	cystathionine gamma-synthase activity
FFM81_011525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFM81_011530	COG4597	amino acid ABC transporter
FFM81_011535	COG0765	amino acid transport
FFM81_011540	COG1126	abc transporter atp-binding protein
FFM81_011600	COG1278	Cold shock
FFM81_011630	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FFM81_011645	COG0436	Aminotransferase
FFM81_011655	COG3243	poly(R)-hydroxyalkanoic acid synthase
FFM81_011665	COG0436	Aminotransferase
FFM81_011680	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FFM81_011685	COG0511	ligase activity, forming carbon-carbon bonds
FFM81_011695	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FFM81_011705	COG4765	Protein conserved in bacteria
FFM81_011720	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FFM81_011735	COG3811	Belongs to the UPF0386 family
FFM81_011770	COG0154	amidase activity
FFM81_011775	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FFM81_011780	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FFM81_011805	COG0024	Methionine aminopeptidase
FFM81_011810	COG2003	Belongs to the UPF0758 family
FFM81_011825	COG1032	radical SAM domain protein
FFM81_011835	COG0544	peptidyl-prolyl cis-trans isomerase activity
FFM81_011865	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FFM81_011890	COG1862	Preprotein translocase
FFM81_011905	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FFM81_011910	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FFM81_011915	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FFM81_011920	COG0805	protein transport
FFM81_011925	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FFM81_011930	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FFM81_011935	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FFM81_011940	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FFM81_011945	COG1472	Belongs to the glycosyl hydrolase 3 family
FFM81_011955	COG0018	arginyl-trna synthetase
FFM81_011960	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FFM81_011990	COG0525	valine-tRNA ligase activity
FFM81_012000	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FFM81_012050	COG0753	catalase activity
FFM81_012090	COG0450	alkyl hydroperoxide reductase
FFM81_012095	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FFM81_012100	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FFM81_012100	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FFM81_012105	COG3707	response regulator
FFM81_012110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FFM81_012120	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FFM81_012130	COG0243	molybdopterin cofactor binding
FFM81_012135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FFM81_012145	COG1522	sequence-specific DNA binding
FFM81_012160	COG0415	Belongs to the DNA photolyase family
FFM81_012165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FFM81_012170	COG0300	oxidoreductase activity
FFM81_012175	COG3806	Anti-sigma factor
FFM81_012180	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FFM81_012185	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FFM81_012190	COG2897	thiosulfate sulfurtransferase activity
FFM81_012215	COG0686	Belongs to the AlaDH PNT family
FFM81_012220	COG1522	sequence-specific DNA binding
FFM81_012235	COG0737	Belongs to the 5'-nucleotidase family
FFM81_012245	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FFM81_012255	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_012275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FFM81_012295	COG1546	Belongs to the CinA family
FFM81_012295	COG1058	Belongs to the CinA family
FFM81_012305	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FFM81_012315	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FFM81_012335	COG0625	glutathione transferase activity
FFM81_012345	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FFM81_012355	COG1522	sequence-specific DNA binding
FFM81_012360	COG1522	sequence-specific DNA binding
FFM81_012405	COG2226	methyltransferase
FFM81_012415	COG4585	Histidine kinase
FFM81_012420	COG2197	response regulator
FFM81_012440	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FFM81_012445	COG0673	inositol 2-dehydrogenase activity
FFM81_012460	COG3842	ATPase activity
FFM81_012465	COG0395	ABC-type sugar transport system, permease component
FFM81_012470	COG1175	transmembrane transport
FFM81_012475	COG1653	transport
FFM81_012480	COG1012	belongs to the aldehyde dehydrogenase family
FFM81_012485	COG1024	Enoyl-CoA hydratase
FFM81_012495	COG1609	Transcriptional regulator
FFM81_012500	COG5002	protein histidine kinase activity
FFM81_012520	COG0583	DNA-binding transcription factor activity
FFM81_012525	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_012530	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FFM81_012535	COG0508	dehydrogenase complex catalyzes the overall conversion of
FFM81_012535	COG0596	Alpha beta hydrolase
FFM81_012550	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FFM81_012570	COG0129	dihydroxy-acid dehydratase activity
FFM81_012580	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FFM81_012585	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FFM81_012595	COG0203	ribosomal protein L17
FFM81_012600	COG0202	RNA polymerase activity
FFM81_012605	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FFM81_012610	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FFM81_012615	COG0563	adenylate kinase activity
FFM81_012625	COG0200	Binds to the 23S rRNA
FFM81_012630	COG1841	ribosomal large subunit assembly
FFM81_012635	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FFM81_012640	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FFM81_012645	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FFM81_012650	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FFM81_012655	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FFM81_012660	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FFM81_012665	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FFM81_012670	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FFM81_012675	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FFM81_012680	COG0255	Belongs to the universal ribosomal protein uL29 family
FFM81_012685	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FFM81_012690	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FFM81_012695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FFM81_012700	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FFM81_012705	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FFM81_012710	COG0089	rRNA binding
FFM81_012715	COG0088	Forms part of the polypeptide exit tunnel
FFM81_012720	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FFM81_012725	COG0051	transcription antitermination factor activity, RNA binding
FFM81_012730	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FFM81_012735	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FFM81_012740	COG0049	tRNA binding
FFM81_012745	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FFM81_012755	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FFM81_012760	COG0085	RNA polymerase activity
FFM81_012765	COG0222	ribosome binding
FFM81_012770	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FFM81_012775	COG0081	regulation of translation
FFM81_012780	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FFM81_012790	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FFM81_012800	COG1086	Polysaccharide biosynthesis protein
FFM81_012805	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FFM81_012825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FFM81_012860	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FFM81_012880	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FFM81_012885	COG0860	N-Acetylmuramoyl-L-alanine amidase
FFM81_012890	COG1530	ribonuclease E activity
FFM81_012905	COG1960	acyl-CoA dehydrogenase activity
FFM81_012910	COG0540	Belongs to the ATCase OTCase family
FFM81_012915	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FFM81_012920	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FFM81_012925	COG0758	DNA mediated transformation
FFM81_012930	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FFM81_012935	COG0557	exoribonuclease II activity
FFM81_012945	COG0477	Major facilitator Superfamily
FFM81_012950	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FFM81_012960	COG0784	Response regulator, receiver
FFM81_012975	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FFM81_012995	COG1136	(ABC) transporter
FFM81_013005	COG0442	prolyl-tRNA aminoacylation
FFM81_013020	COG0346	lactoylglutathione lyase activity
FFM81_013030	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FFM81_013030	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FFM81_013035	COG1007	ATP synthesis coupled electron transport
FFM81_013060	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFM81_013065	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FFM81_013075	COG3743	rRNA binding
FFM81_013075	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FFM81_013080	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FFM81_013085	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FFM81_013095	COG0649	NAD binding
FFM81_013100	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFM81_013105	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFM81_013110	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFM81_013135	COG0386	Belongs to the glutathione peroxidase family
FFM81_013155	COG0667	Aldo Keto reductase
FFM81_013165	COG0697	spore germination
FFM81_013170	COG0776	regulation of translation
FFM81_013175	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FFM81_013180	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FFM81_013185	COG0740	serine-type endopeptidase activity
FFM81_013190	COG3706	GGDEF domain
FFM81_013195	COG2124	cytochrome p450
FFM81_013205	COG5001	Diguanylate cyclase
FFM81_013225	COG1832	CoA-binding protein
FFM81_013240	COG1024	Enoyl-CoA hydratase
FFM81_013255	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FFM81_013260	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FFM81_013265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FFM81_013265	COG2755	lipolytic protein G-D-S-L family
FFM81_013275	COG0010	Belongs to the arginase family
FFM81_013280	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FFM81_013290	COG1612	heme a metabolic process
FFM81_013315	COG0297	glycogen (starch) synthase activity
FFM81_013330	COG0395	ABC-type sugar transport system, permease component
FFM81_013335	COG1175	transmembrane transport
FFM81_013355	COG1940	carbohydrate kinase activity
FFM81_013380	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FFM81_013390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FFM81_013440	COG0776	regulation of translation
FFM81_013445	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FFM81_013450	COG0416	fatty acid biosynthetic process
FFM81_013470	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FFM81_013475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FFM81_013480	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FFM81_013515	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FFM81_013520	COG1088	dTDP-glucose 4,6-dehydratase activity
FFM81_013525	COG1091	dTDP-4-dehydrorhamnose reductase activity
FFM81_013530	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FFM81_013540	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FFM81_013540	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FFM81_013545	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FFM81_013550	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FFM81_013570	COG0113	porphobilinogen synthase activity
FFM81_013580	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FFM81_013600	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FFM81_013610	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FFM81_013615	COG2132	Multicopper oxidase
FFM81_013620	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FFM81_013625	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FFM81_013635	COG0248	Ppx GppA phosphatase
FFM81_013640	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FFM81_013650	COG0628	permease
FFM81_013655	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FFM81_013660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FFM81_013670	COG3454	Phosphonate metabolism
FFM81_013675	COG0494	nUDIX hydrolase
FFM81_013680	COG0243	molybdopterin cofactor binding
FFM81_013685	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FFM81_013700	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_013705	COG0322	excinuclease ABC activity
FFM81_013710	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FFM81_013720	COG0314	molybdopterin synthase activity
FFM81_013740	COG0105	UTP biosynthetic process
FFM81_013760	COG0488	(ABC) transporter
FFM81_013770	COG1505	serine-type exopeptidase activity
FFM81_013780	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FFM81_013790	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FFM81_013795	COG0671	phosphoesterase, PA-phosphatase related
FFM81_013810	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FFM81_013820	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FFM81_013825	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FFM81_013830	COG0194	GDP metabolic process
FFM81_013835	COG1561	YicC-like family, N-terminal region
FFM81_013840	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FFM81_013845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FFM81_013850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FFM81_013860	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FFM81_013865	COG0667	Aldo Keto reductase
FFM81_013870	COG0360	Binds together with S18 to 16S ribosomal RNA
FFM81_013875	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FFM81_013890	COG0305	Participates in initiation and elongation during chromosome replication
FFM81_013910	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FFM81_013915	COG1280	lysine exporter protein (LysE YggA)
FFM81_013925	COG1286	toxin biosynthetic process
FFM81_013930	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FFM81_013935	COG4221	oxidoreductase activity
FFM81_013945	COG0215	cysteine-tRNA ligase activity
FFM81_013970	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FFM81_013990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFM81_014010	COG5265	(ABC) transporter
FFM81_014015	COG0688	phosphatidylethanolamine metabolic process
FFM81_014035	COG1742	UPF0060 membrane protein
FFM81_014040	COG1051	belongs to the nudix hydrolase family
FFM81_014060	COG0354	folic acid binding
FFM81_014065	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FFM81_014075	COG0668	transmembrane transport
FFM81_014080	COG2032	superoxide dismutase activity
FFM81_014090	COG3300	MHYT domain
FFM81_014090	COG5001	Diguanylate cyclase
FFM81_014095	COG1418	mRNA catabolic process
FFM81_014110	COG1381	Involved in DNA repair and RecF pathway recombination
FFM81_014120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FFM81_014125	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FFM81_014130	COG0571	ribonuclease III activity
FFM81_014135	COG0681	Belongs to the peptidase S26 family
FFM81_014140	COG0736	holo-[acyl-carrier-protein] synthase activity
FFM81_014160	COG1758	RNA polymerase activity
FFM81_014170	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FFM81_014175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FFM81_014205	COG0673	inositol 2-dehydrogenase activity
FFM81_014215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFM81_014230	COG3718	enzyme involved in inositol metabolism
FFM81_014280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FFM81_014300	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FFM81_014310	COG3795	YCII-related domain
FFM81_014315	COG3795	YCII-related domain
FFM81_014325	COG4941	Belongs to the sigma-70 factor family
FFM81_014335	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FFM81_014340	COG0463	Glycosyl transferase, family 2
FFM81_014345	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FFM81_014350	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FFM81_014420	COG4964	Belongs to the GSP D family
FFM81_014440	COG0330	HflC and HflK could
FFM81_014455	COG0174	glutamine synthetase
FFM81_014465	COG2814	Major facilitator Superfamily
FFM81_014470	COG2239	Acts as a magnesium transporter
FFM81_014485	COG1376	ErfK ybiS ycfS ynhG family protein
FFM81_014495	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_014515	COG0443	Heat shock 70 kDa protein
FFM81_014545	COG3290	protein histidine kinase activity
FFM81_014545	COG0840	transmembrane signaling receptor activity
FFM81_014550	COG0308	aminopeptidase N
FFM81_014555	COG2202	Pas domain
FFM81_014555	COG2205	protein histidine kinase activity
FFM81_014560	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FFM81_014565	COG2205	protein histidine kinase activity
FFM81_014570	COG0745	RESPONSE REGULATOR receiver
FFM81_014575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FFM81_014580	COG3088	subunit of a heme lyase
FFM81_014585	COG1138	Cytochrome C-type biogenesis protein
FFM81_014590	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FFM81_014595	COG4235	cytochrome complex assembly
FFM81_014635	COG1309	transcriptional regulator
FFM81_014650	COG0625	glutathione transferase activity
FFM81_014665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFM81_014670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FFM81_014675	COG0583	DNA-binding transcription factor activity
FFM81_014690	COG0583	DNA-binding transcription factor activity
FFM81_014710	COG3239	Fatty acid desaturase
FFM81_014740	COG2983	Belongs to the UPF0260 family
FFM81_014745	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FFM81_014790	COG2205	protein histidine kinase activity
FFM81_014805	COG2166	iron-sulfur cluster assembly
FFM81_014810	COG4957	zinc ion binding
FFM81_014815	COG1320	monovalent cation:proton antiporter activity
FFM81_014820	COG2212	antiporter activity
FFM81_014825	COG1863	multisubunit Na H antiporter MnhE subunit
FFM81_014830	COG0651	ATP synthesis coupled electron transport
FFM81_014835	COG1006	Multisubunit Na H antiporter MnhC subunit
FFM81_014840	COG2111	Na H antiporter
FFM81_014845	COG2111	Na H antiporter
FFM81_014845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FFM81_014855	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FFM81_014860	COG0519	Catalyzes the synthesis of GMP from XMP
FFM81_014875	COG1272	protein, Hemolysin III
FFM81_014885	COG2514	catechol 2,3-dioxygenase activity
FFM81_014920	COG0477	Major facilitator Superfamily
FFM81_014925	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FFM81_014960	COG2010	Cytochrome c
FFM81_014985	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FFM81_015000	COG0730	response to heat
FFM81_015020	COG0625	glutathione transferase activity
FFM81_015045	COG0583	DNA-binding transcription factor activity
FFM81_015050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FFM81_015055	COG1064	alcohol dehydrogenase
FFM81_015070	COG1253	flavin adenine dinucleotide binding
FFM81_015075	COG4106	trans-aconitate 2-methyltransferase activity
FFM81_015080	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FFM81_015095	COG0433	COG0433 Predicted ATPase
FFM81_015100	COG0488	(ABC) transporter
FFM81_015105	COG0488	(ABC) transporter
FFM81_015130	COG1764	response to oxidative stress
FFM81_015135	COG1846	Transcriptional regulator
FFM81_015145	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FFM81_015155	COG1278	Cold shock
FFM81_015160	COG1376	ErfK ybiS ycfS ynhG family protein
FFM81_015165	COG1376	ErfK ybiS ycfS ynhG family protein
FFM81_015180	COG1793	dna ligase
FFM81_015190	COG0596	Alpha beta hydrolase
FFM81_015210	COG0435	Glutathione S-transferase
FFM81_015215	COG0583	DNA-binding transcription factor activity
FFM81_015230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FFM81_015255	COG1349	DNA-binding transcription factor activity
FFM81_015290	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FFM81_015305	COG1309	transcriptional regulator
FFM81_015310	COG1012	belongs to the aldehyde dehydrogenase family
FFM81_015315	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FFM81_015335	COG1959	2 iron, 2 sulfur cluster binding
FFM81_015340	COG0175	sulfate reduction
FFM81_015345	COG0175	sulfate reduction
FFM81_015350	COG2895	sulfate adenylyltransferase (ATP) activity
FFM81_015360	COG0583	DNA-binding transcription factor activity
FFM81_015365	COG1609	Transcriptional regulator
FFM81_015560	COG0640	Transcriptional regulator
FFM81_015570	COG0625	glutathione transferase activity
FFM81_015595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FFM81_015600	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FFM81_015610	COG3264	Mechanosensitive ion channel
FFM81_015610	COG1511	domain protein
FFM81_015620	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_015625	COG0640	Transcriptional regulator
FFM81_015655	COG0235	Class ii aldolase
FFM81_015660	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FFM81_015680	COG5265	(ABC) transporter
FFM81_015685	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FFM81_015840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FFM81_015895	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FFM81_015910	COG0732	type I restriction modification DNA specificity domain
FFM81_015915	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FFM81_015970	COG0574	Belongs to the PEP-utilizing enzyme family
FFM81_015970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FFM81_015975	COG1196	nuclear chromosome segregation
FFM81_015985	COG1879	ABC-type sugar transport system periplasmic component
FFM81_015990	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFM81_015995	COG1129	ABC transporter
FFM81_016000	COG1609	Transcriptional regulator
FFM81_016015	COG1194	a g-specific adenine glycosylase
FFM81_016030	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FFM81_016075	COG2972	Histidine kinase
FFM81_016075	COG0840	transmembrane signaling receptor activity
FFM81_016085	COG2814	Major facilitator Superfamily
FFM81_016090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FFM81_016105	COG0612	Peptidase, M16
FFM81_016115	COG5001	Diguanylate cyclase
FFM81_016115	COG3300	MHYT domain
FFM81_016120	COG1522	sequence-specific DNA binding
FFM81_016125	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FFM81_016135	COG1473	amidohydrolase
FFM81_016150	COG0803	Belongs to the bacterial solute-binding protein 9 family
FFM81_016155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FFM81_016165	COG0678	peroxiredoxin activity
FFM81_016165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FFM81_016175	COG1678	Uncharacterized ACR, COG1678
FFM81_016205	COG0328	RNA-DNA hybrid ribonuclease activity
FFM81_016210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FFM81_016215	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FFM81_016220	COG3346	SURF1 family
FFM81_016235	COG0454	-acetyltransferase
FFM81_016240	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FFM81_016250	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FFM81_016260	COG0109	protoheme IX farnesyltransferase activity
FFM81_016265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FFM81_016270	COG1565	acr, cog1565
FFM81_016270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FFM81_016285	COG0312	modulator of DNA gyrase
FFM81_016300	COG1686	Belongs to the peptidase S11 family
FFM81_016310	COG0259	pyridoxamine-phosphate oxidase activity
FFM81_016320	COG0484	heat shock protein binding
FFM81_016325	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FFM81_016345	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FFM81_016350	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FFM81_016350	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FFM81_016355	COG3214	Protein conserved in bacteria
FFM81_016360	COG1122	ATPase activity
FFM81_016365	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FFM81_016370	COG1268	BioY protein
FFM81_016375	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FFM81_016380	COG0583	DNA-binding transcription factor activity
FFM81_016385	COG0662	Cupin 2, conserved barrel domain protein
FFM81_016400	COG0123	including yeast histone deacetylase and acetoin utilization protein
FFM81_016405	COG1722	exodeoxyribonuclease VII activity
FFM81_016415	COG1741	Belongs to the pirin family
FFM81_016425	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FFM81_016430	COG0840	transmembrane signaling receptor activity
FFM81_016445	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FFM81_016460	COG1960	acyl-CoA dehydrogenase activity
FFM81_016485	COG4638	Rieske (2fe-2S)
FFM81_016495	COG0009	L-threonylcarbamoyladenylate synthase
FFM81_016515	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FFM81_016525	COG0406	alpha-ribazole phosphatase activity
FFM81_016530	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FFM81_016535	COG2183	response to ionizing radiation
FFM81_016540	COG0751	glycine-tRNA ligase activity
FFM81_016545	COG0840	transmembrane signaling receptor activity
FFM81_016555	COG0151	Belongs to the GarS family
FFM81_016565	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FFM81_016570	COG1704	LemA family
FFM81_016580	COG0752	glycyl-tRNA synthetase alpha subunit
FFM81_016600	COG1914	H( )-stimulated, divalent metal cation uptake system
FFM81_016615	COG0142	geranyltranstransferase activity
FFM81_016625	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FFM81_016630	COG0521	Mo-molybdopterin cofactor biosynthetic process
FFM81_016650	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FFM81_016655	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FFM81_016660	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FFM81_016670	COG0356	it plays a direct role in the translocation of protons across the membrane
FFM81_016685	COG3158	transport of potassium into the cell
FFM81_016690	COG0598	Magnesium transport protein CorA
FFM81_016695	COG0489	protein tyrosine kinase activity
FFM81_016705	COG2197	response regulator
FFM81_016710	COG1414	Transcriptional regulator
FFM81_016715	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_016720	COG3734	2-keto-3-deoxy-galactonokinase
FFM81_016725	COG0800	Aldolase
FFM81_016730	COG3386	PFAM SMP-30 Gluconolaconase
FFM81_016740	COG5001	Diguanylate cyclase
FFM81_016740	COG3300	MHYT domain
FFM81_016745	COG0745	RESPONSE REGULATOR receiver
FFM81_016750	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FFM81_016770	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFM81_016775	COG1802	Transcriptional regulator
FFM81_016780	COG1663	tetraacyldisaccharide 4'-kinase activity
FFM81_016790	COG1519	Transferase
FFM81_016800	COG0483	inositol monophosphate 1-phosphatase activity
FFM81_016805	COG0312	modulator of DNA gyrase
FFM81_016820	COG0742	ribosomal rna small subunit methyltransferase
FFM81_016825	COG1187	pseudouridine synthase activity
FFM81_016830	COG0590	tRNA wobble adenosine to inosine editing
FFM81_016845	COG0196	riboflavin kinase activity
FFM81_016855	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FFM81_016870	COG0625	glutathione transferase activity
FFM81_016875	COG2259	Doxx family
FFM81_016880	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FFM81_016885	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FFM81_016890	COG0124	histidyl-tRNA synthetase
FFM81_016910	COG0667	Aldo Keto reductase
FFM81_016925	COG2818	Glycosylase
FFM81_016930	COG1376	ErfK ybiS ycfS ynhG family protein
FFM81_016935	COG1376	ErfK ybiS ycfS ynhG family protein
FFM81_016935	COG1388	LysM domain
FFM81_016950	COG0247	lactate metabolic process
FFM81_016955	COG0277	FAD linked oxidase domain protein
FFM81_016960	COG0277	FAD linked oxidase domain protein
FFM81_016965	COG0583	DNA-binding transcription factor activity
FFM81_016975	COG4221	oxidoreductase activity
FFM81_016975	COG3321	synthase
FFM81_016975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FFM81_016975	COG0604	alcohol dehydrogenase
FFM81_016980	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FFM81_016995	COG0306	phosphate transporter
FFM81_017020	COG0583	DNA-binding transcription factor activity
FFM81_017035	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_017040	COG0583	DNA-binding transcription factor activity
FFM81_017060	COG0477	Major facilitator Superfamily
FFM81_017070	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FFM81_017085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFM81_017100	COG1442	glycosyl transferase family 8
FFM81_017120	COG1215	transferase activity, transferring glycosyl groups
FFM81_017125	COG2226	methyltransferase
FFM81_017140	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FFM81_017155	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
FFM81_017160	COG2089	acid synthase
FFM81_017165	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FFM81_017170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FFM81_017175	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FFM81_017180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFM81_017220	COG1595	DNA-templated transcription, initiation
FFM81_017235	COG1755	Isoprenylcysteine carboxyl methyltransferase
FFM81_017240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FFM81_017245	COG3265	gluconokinase activity
FFM81_017250	COG4608	Belongs to the ABC transporter superfamily
FFM81_017255	COG0444	Belongs to the ABC transporter superfamily
FFM81_017260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFM81_017265	COG0601	transmembrane transport
FFM81_017270	COG0747	negative chemotaxis
FFM81_017275	COG1959	2 iron, 2 sulfur cluster binding
FFM81_017320	COG2205	protein histidine kinase activity
FFM81_017325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FFM81_017335	COG1177	transmembrane transport
FFM81_017340	COG1176	ABC-type spermidine putrescine transport system, permease component I
FFM81_017345	COG3842	ATPase activity
FFM81_017350	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FFM81_017360	COG2224	Isocitrate lyase
FFM81_017385	COG2972	Histidine kinase
FFM81_017385	COG0840	transmembrane signaling receptor activity
FFM81_017395	COG2081	HI0933 family
FFM81_017405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FFM81_017410	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FFM81_017415	COG0363	glucosamine-6-phosphate deaminase activity
FFM81_017420	COG0129	dihydroxy-acid dehydratase activity
FFM81_017430	COG3842	ATPase activity
FFM81_017435	COG0366	Alpha amylase catalytic
FFM81_017440	COG0395	ABC-type sugar transport system, permease component
FFM81_017445	COG1175	transmembrane transport
FFM81_017450	COG1653	transport
FFM81_017455	COG1609	Transcriptional regulator
FFM81_017470	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FFM81_017495	COG1684	flagellar biosynthetic protein fliR
FFM81_017500	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FFM81_017505	COG4794	Type iii secretion
FFM81_017515	COG5443	negative regulation of bacterial-type flagellum assembly
FFM81_017535	COG1749	Flagellar hook protein flgE
FFM81_017560	COG1360	Flagellar Motor Protein
FFM81_017570	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FFM81_017595	COG1522	sequence-specific DNA binding
FFM81_017605	COG1338	Plays a role in the flagellum-specific transport system
FFM81_017615	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FFM81_017625	COG1706	bacterial-type flagellum-dependent cell motility
FFM81_017630	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FFM81_017635	COG4786	Flagellar basal body rod
FFM81_017640	COG1677	Flagellar hook-basal body complex protein FliE
FFM81_017645	COG1558	bacterial-type flagellum-dependent cell motility
FFM81_017650	COG1815	bacterial-type flagellum-dependent cell motility
FFM81_017660	COG1157	protein secretion by the type III secretion system
FFM81_017665	COG4786	Flagellar basal body rod
FFM81_017670	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FFM81_017675	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FFM81_017680	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FFM81_017685	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FFM81_017690	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FFM81_017705	COG2771	luxR family
FFM81_017710	COG1766	The M ring may be actively involved in energy transduction
FFM81_017720	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FFM81_017725	COG0745	RESPONSE REGULATOR receiver
FFM81_017730	COG2201	protein-glutamate methylesterase activity
FFM81_017735	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FFM81_017740	COG0835	chemotaxis
FFM81_017745	COG0643	Histidine kinase
FFM81_017745	COG2198	Histidine kinase
FFM81_017750	COG0745	RESPONSE REGULATOR receiver
FFM81_017760	COG0840	transmembrane signaling receptor activity
FFM81_017765	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FFM81_017775	COG4651	solute:proton antiporter activity
FFM81_017775	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FFM81_017790	COG2205	protein histidine kinase activity
FFM81_017800	COG2197	response regulator
FFM81_017805	COG0745	RESPONSE REGULATOR receiver
FFM81_017815	COG4251	negative regulation of phosphorylation
FFM81_017825	COG4251	negative regulation of phosphorylation
FFM81_017830	COG0346	lactoylglutathione lyase activity
FFM81_017860	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FFM81_017865	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FFM81_017880	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FFM81_017880	COG2755	lipolytic protein G-D-S-L family
FFM81_017890	COG1609	Transcriptional regulator
FFM81_017895	COG1063	alcohol dehydrogenase
FFM81_017910	COG0673	inositol 2-dehydrogenase activity
FFM81_017920	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_017930	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FFM81_017935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFM81_017940	COG1940	carbohydrate kinase activity
FFM81_017945	COG1082	Xylose isomerase domain protein TIM barrel
FFM81_017955	COG1175	transmembrane transport
FFM81_017960	COG0395	ABC-type sugar transport system, permease component
FFM81_017970	COG3842	ATPase activity
FFM81_017975	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_018005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFM81_018015	COG3174	membrane
FFM81_018030	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FFM81_018035	COG0424	maF-like protein
FFM81_018040	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FFM81_018045	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FFM81_018050	COG5328	Belongs to the UPF0262 family
FFM81_018055	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FFM81_018065	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FFM81_018115	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FFM81_018120	COG3300	MHYT domain
FFM81_018120	COG5001	Diguanylate cyclase
FFM81_018130	COG0436	Aminotransferase
FFM81_018135	COG1970	mechanosensitive ion channel activity
FFM81_018140	COG0784	Response regulator, receiver
FFM81_018140	COG2198	Histidine kinase
FFM81_018140	COG2205	protein histidine kinase activity
FFM81_018170	COG1278	Cold shock
FFM81_018175	COG1250	3-hydroxyacyl-CoA dehydrogenase
FFM81_018175	COG1024	Enoyl-CoA hydratase
FFM81_018185	COG0183	Belongs to the thiolase family
FFM81_018190	COG1960	acyl-CoA dehydrogenase activity
FFM81_018210	COG0730	response to heat
FFM81_018240	COG1201	RNA secondary structure unwinding
FFM81_018250	COG1959	2 iron, 2 sulfur cluster binding
FFM81_018255	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FFM81_018280	COG0534	Mate efflux family protein
FFM81_018285	COG0167	dihydroorotate dehydrogenase activity
FFM81_018320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFM81_018340	COG4221	oxidoreductase activity
FFM81_018350	COG1846	Transcriptional regulator
FFM81_018365	COG1566	PFAM secretion protein HlyD family protein
FFM81_018385	COG0717	Belongs to the dCTP deaminase family
FFM81_018395	COG2967	ApaG domain
FFM81_018400	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FFM81_018405	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FFM81_018410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FFM81_018420	COG0745	RESPONSE REGULATOR receiver
FFM81_018425	COG0704	Plays a role in the regulation of phosphate uptake
FFM81_018430	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FFM81_018440	COG0573	inorganic phosphate transmembrane transporter activity
FFM81_018445	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FFM81_018450	COG5002	protein histidine kinase activity
FFM81_018455	COG2326	polyphosphate kinase activity
FFM81_018485	COG2814	Major facilitator Superfamily
FFM81_018495	COG4178	(ABC) transporter
FFM81_018505	COG2721	sulfolactate sulfo-lyase activity
FFM81_018530	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFM81_018535	COG1063	alcohol dehydrogenase
FFM81_018540	COG3142	Participates in the control of copper homeostasis
FFM81_018545	COG0583	DNA-binding transcription factor activity
FFM81_018555	COG1732	Glycine betaine
FFM81_018560	COG1174	glycine betaine transport
FFM81_018565	COG1125	glycine betaine transport
FFM81_018570	COG1174	glycine betaine transport
FFM81_018580	COG3250	beta-galactosidase activity
FFM81_018590	COG0318	PFAM AMP-dependent synthetase and ligase
FFM81_018595	COG0166	Belongs to the GPI family
FFM81_018605	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FFM81_018615	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FFM81_018620	COG1309	transcriptional regulator
FFM81_018650	COG0418	dihydroorotase activity
FFM81_018655	COG1072	(Pantothenic acid kinase))
FFM81_018675	COG1940	carbohydrate kinase activity
FFM81_018695	COG0604	alcohol dehydrogenase
FFM81_018705	COG1309	transcriptional regulator
FFM81_018725	COG3300	MHYT domain
FFM81_018725	COG5001	Diguanylate cyclase
FFM81_018730	COG3938	Belongs to the proline racemase family
FFM81_018735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FFM81_018745	COG0667	Aldo Keto reductase
FFM81_018755	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FFM81_018785	COG0259	pyridoxamine-phosphate oxidase activity
FFM81_018790	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_018830	COG2201	protein-glutamate methylesterase activity
FFM81_018855	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FFM81_018860	COG3119	arylsulfatase activity
FFM81_018880	COG0840	transmembrane signaling receptor activity
FFM81_018885	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FFM81_018890	COG0594	ribonuclease P activity
FFM81_018895	COG0706	membrane insertase activity
FFM81_018900	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FFM81_018905	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FFM81_018915	COG5484	DNA packaging
FFM81_018920	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FFM81_018935	COG1304	FMN binding
FFM81_018945	COG2169	Transcriptional regulator
FFM81_018945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FFM81_018950	COG1032	radical SAM domain protein
FFM81_018970	COG2171	N-acyltransferase activity
FFM81_018975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FFM81_018985	COG0101	tRNA pseudouridine synthase activity
FFM81_018990	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FFM81_019005	COG0242	peptide deformylase activity
FFM81_019015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFM81_019020	COG0840	transmembrane signaling receptor activity
FFM81_019025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFM81_019030	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FFM81_019045	COG1137	ATPase activity
FFM81_019050	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FFM81_019065	COG0776	regulation of translation
FFM81_019090	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FFM81_019090	COG0116	Belongs to the methyltransferase superfamily
FFM81_019095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FFM81_019100	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FFM81_019105	COG5002	protein histidine kinase activity
FFM81_019105	COG2205	protein histidine kinase activity
FFM81_019105	COG0784	Response regulator, receiver
FFM81_019120	COG0281	malic enzyme
FFM81_019120	COG0280	phosphate acetyltransferase
FFM81_019125	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FFM81_019155	COG0180	Tryptophanyl-tRNA synthetase
FFM81_019165	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FFM81_019195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FFM81_019200	COG1702	phosphate starvation-inducible protein PhoH
FFM81_019205	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FFM81_019210	COG4535	Mg2 and Co2 transporter CorC
FFM81_019215	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FFM81_019220	COG1396	sequence-specific DNA binding
FFM81_019225	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FFM81_019230	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FFM81_019240	COG0071	Belongs to the small heat shock protein (HSP20) family
FFM81_019250	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FFM81_019255	COG1420	regulation of RNA biosynthetic process
FFM81_019260	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FFM81_019270	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FFM81_019275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FFM81_019285	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FFM81_019290	COG0268	Binds directly to 16S ribosomal RNA
FFM81_019295	COG1024	Enoyl-CoA hydratase
FFM81_019300	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FFM81_019305	COG2226	methyltransferase
FFM81_019310	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FFM81_019320	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FFM81_019340	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FFM81_019345	COG2814	Major facilitator Superfamily
FFM81_019350	COG0583	DNA-binding transcription factor activity
FFM81_019360	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FFM81_019375	COG2807	transmembrane transport
FFM81_019390	COG0625	glutathione transferase activity
FFM81_019395	COG0583	DNA-binding transcription factor activity
FFM81_019400	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FFM81_019405	COG0756	dUTP diphosphatase activity
FFM81_019415	COG1522	sequence-specific DNA binding
FFM81_019420	COG0697	spore germination
FFM81_019425	COG0783	Belongs to the Dps family
FFM81_019435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FFM81_019450	COG0189	ligase activity
FFM81_019455	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFM81_019470	COG1609	Transcriptional regulator
FFM81_019480	COG0792	nuclease activity
FFM81_019485	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FFM81_019500	COG3963	phosphatidate phosphatase activity
FFM81_019510	COG0284	orotidine-5'-phosphate decarboxylase activity
FFM81_019530	COG1968	undecaprenyl-diphosphatase activity
FFM81_019540	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FFM81_019550	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FFM81_019595	COG0519	Catalyzes the synthesis of GMP from XMP
FFM81_019595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FFM81_019600	COG0698	ribose 5-phosphate isomerase
FFM81_019630	COG1881	PFAM PEBP family protein
FFM81_019635	COG2207	Transcriptional regulator
FFM81_019640	COG0583	DNA-binding transcription factor activity
FFM81_019650	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_019670	COG1393	Belongs to the ArsC family
FFM81_019675	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FFM81_019685	COG0625	glutathione transferase activity
FFM81_019690	COG2309	aminopeptidase activity
FFM81_019695	COG0697	spore germination
FFM81_019700	COG1846	Transcriptional regulator
FFM81_019705	COG2249	NAD(P)H dehydrogenase (quinone) activity
FFM81_019710	COG1570	exodeoxyribonuclease VII activity
FFM81_019755	COG3685	Protein conserved in bacteria
FFM81_019765	COG0667	Aldo Keto reductase
FFM81_019775	COG0072	phenylalanine-tRNA ligase activity
FFM81_019775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FFM81_019780	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FFM81_019785	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FFM81_019790	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FFM81_019795	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FFM81_019800	COG0596	Alpha beta hydrolase
FFM81_019800	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FFM81_019825	COG2137	regulation of response to DNA damage stimulus
FFM81_019855	COG0481	GTPase activity
FFM81_019905	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FFM81_019920	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FFM81_019955	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FFM81_019965	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FFM81_019975	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FFM81_019990	COG0583	DNA-binding transcription factor activity
FFM81_019995	COG0747	negative chemotaxis
FFM81_020005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFM81_020020	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FFM81_020030	COG1280	lysine exporter protein (LysE YggA)
FFM81_020060	COG4964	Belongs to the GSP D family
FFM81_020095	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FFM81_020100	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FFM81_020105	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FFM81_020110	COG3577	Aspartyl protease
FFM81_020115	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FFM81_020120	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FFM81_020125	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FFM81_020135	COG1079	Belongs to the binding-protein-dependent transport system permease family
FFM81_020140	COG1079	Belongs to the binding-protein-dependent transport system permease family
FFM81_020145	COG3845	ABC transporter
FFM81_020150	COG1744	ABC transporter substrate-binding protein PnrA-like
FFM81_020180	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FFM81_020195	COG4172	Belongs to the ABC transporter superfamily
FFM81_020200	COG4239	(ABC) transporter, permease
FFM81_020205	COG4174	ABC transporter (Permease)
FFM81_020210	COG4166	transmembrane transport
FFM81_020215	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FFM81_020220	COG1803	Methylglyoxal synthase
FFM81_020225	COG0837	glucose binding
FFM81_020230	COG1132	(ABC) transporter
FFM81_020235	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FFM81_020240	COG0588	phosphoglycerate mutase activity
FFM81_020245	COG2188	Transcriptional regulator
FFM81_020250	COG3624	Phosphonate C-P lyase system protein PhnG
FFM81_020255	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FFM81_020260	COG3626	phosphonate metabolism
FFM81_020265	COG3627	carbon phosphorus lyase activity
FFM81_020270	COG4107	phosphonate C-P lyase system protein PhnK
FFM81_020275	COG4778	phosphonate C-P lyase system protein PhnL
FFM81_020285	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FFM81_020295	COG3639	organic phosphonate transmembrane transporter activity
FFM81_020300	COG3639	organic phosphonate transmembrane transporter activity
FFM81_020305	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FFM81_020310	COG3454	Phosphonate metabolism
FFM81_020315	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FFM81_020320	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FFM81_020320	COG0456	acetyltransferase
FFM81_020325	COG1674	ftsk spoiiie
FFM81_020330	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FFM81_020330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FFM81_020340	COG3300	MHYT domain
FFM81_020340	COG5001	Diguanylate cyclase
FFM81_020345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FFM81_020360	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FFM81_020365	COG0443	Heat shock 70 kDa protein
FFM81_020370	COG0484	heat shock protein binding
FFM81_020380	COG1396	sequence-specific DNA binding
FFM81_020385	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FFM81_020410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFM81_020420	COG3474	cytochrome
FFM81_020425	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FFM81_020430	COG1605	Chorismate mutase
FFM81_020430	COG0077	Prephenate dehydratase
FFM81_020445	COG2378	regulation of single-species biofilm formation
FFM81_020450	COG2816	NAD+ diphosphatase activity
FFM81_020465	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FFM81_020470	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FFM81_020480	COG2258	MOSC domain
FFM81_020485	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FFM81_020490	COG2951	lytic endotransglycosylase activity
FFM81_020500	COG2814	Major facilitator Superfamily
FFM81_020505	COG0779	Required for maturation of 30S ribosomal subunits
FFM81_020520	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FFM81_020525	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FFM81_020530	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FFM81_020535	COG0596	Alpha beta hydrolase
FFM81_020540	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FFM81_020545	COG1185	polyribonucleotide nucleotidyltransferase activity
FFM81_020550	COG2813	Specifically methylates the guanine in position
FFM81_020555	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FFM81_020565	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FFM81_020610	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FFM81_020615	COG0539	negative regulation of cytoplasmic translation
FFM81_020635	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FFM81_020640	COG1012	belongs to the aldehyde dehydrogenase family
FFM81_020645	COG2900	Belongs to the SlyX family
FFM81_020655	COG0246	Mannitol dehydrogenase
FFM81_020670	COG3842	ATPase activity
FFM81_020680	COG0395	ABC-type sugar transport system, permease component
FFM81_020685	COG1175	transmembrane transport
FFM81_020695	COG1309	transcriptional regulator
FFM81_020700	COG0673	inositol 2-dehydrogenase activity
FFM81_020715	COG0673	inositol 2-dehydrogenase activity
FFM81_020750	COG1215	transferase activity, transferring glycosyl groups
FFM81_020755	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FFM81_020770	COG2197	response regulator
FFM81_020840	COG1643	Atp-dependent helicase
FFM81_020850	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FFM81_020865	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FFM81_020870	COG2124	cytochrome p450
FFM81_020880	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FFM81_020885	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FFM81_020890	COG0131	Imidazoleglycerol-phosphate dehydratase
FFM81_020900	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FFM81_020915	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FFM81_020920	COG0107	imidazoleglycerol-phosphate synthase activity
FFM81_020925	COG0140	phosphoribosyl-ATP diphosphatase activity
FFM81_020930	COG1072	(Pantothenic acid kinase))
FFM81_020945	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FFM81_020950	COG0745	RESPONSE REGULATOR receiver
FFM81_020955	COG0642	Histidine kinase
FFM81_020965	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFM81_020965	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFM81_020970	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFM81_020975	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FFM81_020980	COG2205	protein histidine kinase activity
FFM81_020985	COG3178	'Phosphotransferase
FFM81_020990	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FFM81_020995	COG2887	Belongs to the helicase family. UvrD subfamily
FFM81_021020	COG0159	tryptophan synthase activity
FFM81_021025	COG0133	tryptophan synthase activity
FFM81_021030	COG0135	phosphoribosylanthranilate isomerase activity
FFM81_021085	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FFM81_021095	COG3030	protein affecting phage T7 exclusion by the F plasmid
FFM81_021100	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FFM81_021105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FFM81_021110	COG0237	dephospho-CoA kinase activity
FFM81_021115	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FFM81_021120	COG0424	maF-like protein
FFM81_021125	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FFM81_021130	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FFM81_021135	COG1981	membrane
FFM81_021140	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FFM81_021145	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FFM81_021150	COG0445	tRNA wobble uridine modification
FFM81_021155	COG0357	Ribosomal RNA small subunit methyltransferase G
FFM81_021180	COG0495	leucyl-tRNA aminoacylation
FFM81_021205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FFM81_021210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FFM81_021210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FFM81_021210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFM81_021215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FFM81_021230	COG0501	Belongs to the peptidase M48B family
FFM81_021245	COG0138	bifunctional purine biosynthesis protein purh
FFM81_021250	COG2270	Major facilitator Superfamily
FFM81_021275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FFM81_021300	COG1175	transmembrane transport
FFM81_021310	COG3842	ATPase activity
FFM81_021315	COG0584	glycerophosphoryl diester phosphodiesterase
FFM81_021320	COG1609	Transcriptional regulator
FFM81_021325	COG0483	inositol monophosphate 1-phosphatase activity
FFM81_021335	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FFM81_021350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFM81_021360	COG0747	negative chemotaxis
FFM81_021370	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFM81_021375	COG1129	ABC transporter
FFM81_021380	COG4213	ABC transporter substrate-binding protein
FFM81_021400	COG1609	Transcriptional regulator
FFM81_021425	COG0395	ABC-type sugar transport system, permease component
FFM81_021430	COG3842	ATPase activity
FFM81_021440	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FFM81_021450	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_021460	COG0402	S-adenosylhomocysteine deaminase activity
FFM81_021465	COG1079	Belongs to the binding-protein-dependent transport system permease family
FFM81_021475	COG3845	ABC transporter
FFM81_021495	COG4589	Belongs to the CDS family
FFM81_021520	COG5564	TIM-barrel signal transduction protein
FFM81_021525	COG5441	Belongs to the UPF0261 family
FFM81_021530	COG1802	Transcriptional regulator
FFM81_021540	COG1175	transmembrane transport
FFM81_021545	COG0395	ABC-type sugar transport system, permease component
FFM81_021560	COG3842	ATPase activity
FFM81_021565	COG0625	glutathione transferase activity
FFM81_021575	COG4172	Belongs to the ABC transporter superfamily
FFM81_021580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFM81_021585	COG0601	transmembrane transport
FFM81_021590	COG0596	Alpha beta hydrolase
FFM81_021625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FFM81_021630	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FFM81_021645	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FFM81_021655	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FFM81_021675	COG0604	alcohol dehydrogenase
FFM81_021675	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_021675	COG3321	synthase
FFM81_021685	COG0318	PFAM AMP-dependent synthetase and ligase
FFM81_021690	COG0183	Belongs to the thiolase family
FFM81_021715	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FFM81_021740	COG1609	Transcriptional regulator
FFM81_021745	COG1653	transport
FFM81_021750	COG1175	transmembrane transport
FFM81_021755	COG0395	ABC-type sugar transport system, permease component
FFM81_021760	COG1621	beta-fructofuranosidase activity
FFM81_021765	COG3842	ATPase activity
FFM81_021835	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFM81_021840	COG1129	ABC transporter
FFM81_021860	COG0754	glutathionylspermidine amidase activity
FFM81_021870	COG3766	membrane
FFM81_021885	COG3789	protein conserved in bacteria
FFM81_021910	COG0765	amino acid transport
FFM81_021935	COG0765	amino acid transport
FFM81_021940	COG0765	amino acid transport
FFM81_021945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFM81_021965	COG1877	trehalose-phosphatase activity
FFM81_021985	COG4214	carbohydrate transport
FFM81_021995	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_022015	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FFM81_022035	COG0583	DNA-binding transcription factor activity
FFM81_022040	COG0667	Aldo Keto reductase
FFM81_022060	COG3842	ATPase activity
FFM81_022065	COG0395	ABC-type sugar transport system, permease component
FFM81_022070	COG1175	transmembrane transport
FFM81_022085	COG1609	Transcriptional regulator
FFM81_022115	COG4372	Transposase
FFM81_022130	COG0511	ligase activity, forming carbon-carbon bonds
FFM81_022135	COG0439	Biotin carboxylase
FFM81_022150	COG1984	allophanate hydrolase subunit 2
FFM81_022155	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FFM81_022160	COG0436	Aminotransferase
FFM81_022170	COG4221	oxidoreductase activity
FFM81_022175	COG0765	amino acid transport
FFM81_022180	COG0765	amino acid transport
FFM81_022190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFM81_022195	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FFM81_022210	COG0251	oxidation-reduction process
FFM81_022225	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFM81_022235	COG1129	ABC transporter
FFM81_022240	COG1879	ABC-type sugar transport system periplasmic component
FFM81_022250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFM81_022265	COG1116	anion transmembrane transporter activity
FFM81_022290	COG2040	homocysteine
FFM81_022315	COG1522	sequence-specific DNA binding
FFM81_022340	COG0840	transmembrane signaling receptor activity
FFM81_022360	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFM81_022365	COG1129	ABC transporter
FFM81_022370	COG2084	Dehydrogenase
FFM81_022375	COG3265	gluconokinase activity
FFM81_022380	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_022385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FFM81_022390	COG1063	alcohol dehydrogenase
FFM81_022395	COG1609	Transcriptional regulator
FFM81_022405	COG2304	oxidoreductase activity
FFM81_022415	COG0657	acetylesterase activity
FFM81_022425	COG4166	transmembrane transport
FFM81_022440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFM81_022445	COG0601	transmembrane transport
FFM81_022450	COG0747	negative chemotaxis
FFM81_022455	COG1024	Enoyl-CoA hydratase
FFM81_022465	COG1960	acyl-CoA dehydrogenase activity
FFM81_022470	COG1250	3-hydroxyacyl-CoA dehydrogenase
FFM81_022470	COG0824	Thioesterase
FFM81_022475	COG3246	L-lysine catabolic process to acetate
FFM81_022485	COG0583	DNA-binding transcription factor activity
FFM81_022505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFM81_022510	COG3300	MHYT domain
FFM81_022510	COG5001	Diguanylate cyclase
FFM81_022520	COG1304	FMN binding
FFM81_022540	COG1079	Belongs to the binding-protein-dependent transport system permease family
FFM81_022545	COG4603	Belongs to the binding-protein-dependent transport system permease family
FFM81_022550	COG3845	ABC transporter
FFM81_022565	COG0625	glutathione transferase activity
FFM81_022595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FFM81_022610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FFM81_022630	COG0454	-acetyltransferase
FFM81_022640	COG1522	sequence-specific DNA binding
FFM81_022660	COG0022	dehydrogenase e1 component
FFM81_022670	COG1960	acyl-CoA dehydrogenase activity
FFM81_022675	COG0183	Belongs to the thiolase family
FFM81_022690	COG1960	acyl-CoA dehydrogenase activity
FFM81_022695	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FFM81_022705	COG2030	dehydratase
FFM81_022710	COG2301	Belongs to the HpcH HpaI aldolase family
FFM81_022720	COG2205	protein histidine kinase activity
FFM81_022725	COG0745	RESPONSE REGULATOR receiver
FFM81_022730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFM81_022745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FFM81_022760	COG3718	enzyme involved in inositol metabolism
FFM81_022765	COG4608	Belongs to the ABC transporter superfamily
FFM81_022770	COG0444	Belongs to the ABC transporter superfamily
FFM81_022775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFM81_022780	COG0601	transmembrane transport
FFM81_022785	COG0747	negative chemotaxis
FFM81_022790	COG1609	Transcriptional regulator
FFM81_022805	COG3250	beta-galactosidase activity
FFM81_022815	COG1175	transmembrane transport
FFM81_022820	COG0395	ABC-type sugar transport system, permease component
FFM81_022840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFM81_022845	COG3842	ATPase activity
FFM81_022855	COG1176	ABC-type spermidine putrescine transport system, permease component I
FFM81_022860	COG0395	ABC-type sugar transport system, permease component
FFM81_022865	COG0251	oxidation-reduction process
FFM81_022870	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FFM81_022875	COG0463	Glycosyl transferase, family 2
FFM81_022890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFM81_022895	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FFM81_022930	COG1177	transmembrane transport
FFM81_022935	COG1176	ABC-type spermidine putrescine transport system, permease component I
FFM81_022950	COG1012	belongs to the aldehyde dehydrogenase family
FFM81_022955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFM81_022965	COG2267	carboxylic ester hydrolase activity
FFM81_022985	COG4521	taurine ABC transporter
FFM81_022990	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FFM81_022995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FFM81_023040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFM81_023050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFM81_023055	COG1126	abc transporter atp-binding protein
FFM81_023065	COG1473	amidohydrolase
FFM81_023070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFM81_023075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFM81_023085	COG3668	Plasmid stabilization system
FFM81_023100	COG1309	transcriptional regulator
FFM81_023120	COG0840	transmembrane signaling receptor activity
FFM81_023125	COG3608	succinylglutamate desuccinylase aspartoacylase
FFM81_023130	COG0006	proline dipeptidase activity
FFM81_023135	COG2423	ornithine cyclodeaminase activity
FFM81_023140	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FFM81_023150	COG0765	amino acid transport
FFM81_023155	COG0765	amino acid transport
FFM81_023165	COG1126	abc transporter atp-binding protein
FFM81_023170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFM81_023175	COG1522	sequence-specific DNA binding
FFM81_023180	COG1012	belongs to the aldehyde dehydrogenase family
FFM81_023185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FFM81_023200	COG1940	carbohydrate kinase activity
FFM81_023230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFM81_023240	COG1349	DNA-binding transcription factor activity
FFM81_023255	COG0657	acetylesterase activity
FFM81_023270	COG1175	transmembrane transport
FFM81_023275	COG0395	ABC-type sugar transport system, permease component
FFM81_023285	COG1349	DNA-binding transcription factor activity
FFM81_023295	COG3842	ATPase activity
FFM81_023300	COG0395	ABC-type sugar transport system, permease component
FFM81_023305	COG1175	transmembrane transport
FFM81_023315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFM81_023320	COG3833	ABC-type maltose transport systems, permease component
FFM81_023325	COG1175	transmembrane transport
FFM81_023340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FFM81_023345	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_023350	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_023370	COG3842	ATPase activity
FFM81_023385	COG1653	transport
FFM81_023390	COG1609	Transcriptional regulator
FFM81_023395	COG1414	Transcriptional regulator
FFM81_023400	COG1475	DNA binding
FFM81_023405	COG1192	Involved in chromosome partitioning
FFM81_023425	COG4191	Histidine kinase
FFM81_023430	COG4566	intracellular signal transduction
FFM81_023435	COG0745	RESPONSE REGULATOR receiver
FFM81_023440	COG4566	intracellular signal transduction
FFM81_023445	COG0640	Transcriptional regulator
FFM81_023465	COG1174	glycine betaine transport
FFM81_023490	COG2986	histidine ammonia-lyase
FFM81_023500	COG2030	dehydratase
FFM81_023515	COG2855	membrane
FFM81_023520	COG0583	DNA-binding transcription factor activity
FFM81_023525	COG4948	Mandelate Racemase Muconate Lactonizing
FFM81_023530	COG4948	Mandelate Racemase Muconate Lactonizing
FFM81_023535	COG4172	Belongs to the ABC transporter superfamily
FFM81_023540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFM81_023545	COG0601	transmembrane transport
FFM81_023550	COG0747	negative chemotaxis
FFM81_023555	COG2186	Transcriptional regulator
FFM81_023560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFM81_023565	COG3386	PFAM SMP-30 Gluconolaconase
FFM81_023570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FFM81_023575	COG0747	negative chemotaxis
FFM81_023580	COG0601	transmembrane transport
FFM81_023585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFM81_023590	COG0444	Belongs to the ABC transporter superfamily
FFM81_023595	COG4608	Belongs to the ABC transporter superfamily
FFM81_023605	COG1672	PFAM Archaeal ATPase
FFM81_023605	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FFM81_023610	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FFM81_023620	COG1278	Cold shock
FFM81_023630	COG1070	Carbohydrate kinase
FFM81_023640	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FFM81_023645	COG0667	Aldo Keto reductase
FFM81_023655	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFM81_023660	COG1129	ABC transporter
FFM81_023685	COG0318	PFAM AMP-dependent synthetase and ligase
FFM81_023695	COG1802	Transcriptional regulator
FFM81_023700	COG0697	spore germination
FFM81_023720	COG0392	lysyltransferase activity
FFM81_023770	COG0747	negative chemotaxis
FFM81_023780	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FFM81_023800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FFM81_023810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFM81_023820	COG0697	spore germination
FFM81_023835	COG1640	4-alpha-glucanotransferase
FFM81_023840	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FFM81_023860	COG2205	protein histidine kinase activity
FFM81_023860	COG3437	response regulator, receiver
FFM81_023860	COG3850	Histidine kinase
FFM81_023860	COG4999	Histidine kinase
FFM81_023885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFM81_023890	COG1120	ATPase activity
FFM81_023900	COG1448	Aminotransferase
FFM81_023905	COG0028	Belongs to the TPP enzyme family
FFM81_023910	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FFM81_023915	COG0366	Alpha amylase catalytic
FFM81_023920	COG0366	Alpha amylase catalytic
FFM81_023940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFM81_023950	COG0598	Magnesium transport protein CorA
FFM81_023960	COG0840	transmembrane signaling receptor activity
FFM81_023965	COG1953	Uracil, thiamine, allantoin
FFM81_023975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FFM81_023990	COG1309	transcriptional regulator
FFM81_024010	COG0395	ABC-type sugar transport system, permease component
FFM81_024015	COG1175	transmembrane transport
FFM81_024030	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FFM81_024050	COG0840	transmembrane signaling receptor activity
FFM81_024060	COG0395	ABC-type sugar transport system, permease component
FFM81_024065	COG1175	transmembrane transport
FFM81_024095	COG2186	Transcriptional regulator
FFM81_024100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FFM81_024110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FFM81_024145	COG1175	transmembrane transport
FFM81_024150	COG0395	ABC-type sugar transport system, permease component
FFM81_024160	COG3842	ATPase activity
FFM81_024215	COG0277	FAD linked oxidase domain protein
FFM81_024215	COG0247	lactate metabolic process
FFM81_024250	COG0473	3-isopropylmalate dehydrogenase activity
FFM81_024255	COG0235	Class ii aldolase
FFM81_024260	COG1609	Transcriptional regulator
FFM81_024265	COG2084	Dehydrogenase
FFM81_024270	COG3622	Belongs to the hyi family
FFM81_024275	COG3395	kinase activity
FFM81_024290	COG0601	transmembrane transport
FFM81_024295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFM81_024310	COG0840	transmembrane signaling receptor activity
FFM81_024325	COG1454	alcohol dehydrogenase
FFM81_024330	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FFM81_024340	COG0693	protein deglycase activity
FFM81_024355	COG5564	TIM-barrel signal transduction protein
FFM81_024375	COG1175	transmembrane transport
FFM81_024390	COG3842	ATPase activity
FFM81_024395	COG3842	ATPase activity
FFM81_024400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FFM81_024410	COG4948	Mandelate Racemase Muconate Lactonizing
FFM81_024415	COG1082	Xylose isomerase domain protein TIM barrel
FFM81_024420	COG1082	Xylose isomerase domain protein TIM barrel
FFM81_024435	COG1522	sequence-specific DNA binding
FFM81_024450	COG2372	response to copper ion
FFM81_024455	COG1276	copper resistance
FFM81_024470	COG4221	oxidoreductase activity
FFM81_024485	COG0583	DNA-binding transcription factor activity
FFM81_024495	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FFM81_024515	COG4176	ABC-type proline glycine betaine transport system permease component
FFM81_024520	COG3791	Glutathione-dependent formaldehyde-activating
FFM81_024525	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FFM81_024530	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FFM81_024540	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FFM81_024545	COG2086	electron transfer activity
FFM81_024555	COG0446	pyridine nucleotide-disulphide oxidoreductase
FFM81_024555	COG1902	pentaerythritol trinitrate reductase activity
FFM81_024565	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FFM81_024575	COG4176	ABC-type proline glycine betaine transport system permease component
FFM81_024585	COG2207	Transcriptional regulator
FFM81_024585	COG3708	Transcriptional regulator
FFM81_024590	COG0243	molybdopterin cofactor binding
FFM81_024595	COG2203	Gaf domain
FFM81_024595	COG3706	GGDEF domain
FFM81_024595	COG4251	negative regulation of phosphorylation
FFM81_024595	COG5001	Diguanylate cyclase
FFM81_024600	COG1012	belongs to the aldehyde dehydrogenase family
FFM81_024610	COG1024	Enoyl-CoA hydratase
FFM81_024635	COG0640	Transcriptional regulator
FFM81_024675	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_024680	COG1012	belongs to the aldehyde dehydrogenase family
FFM81_024690	COG3189	MarR family transcriptional regulator
FFM81_024820	COG0515	serine threonine protein kinase
FFM81_024830	COG3189	MarR family transcriptional regulator
FFM81_024875	COG1802	Transcriptional regulator
FFM81_024880	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_024885	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_024890	COG3938	Belongs to the proline racemase family
FFM81_024895	COG1012	belongs to the aldehyde dehydrogenase family
FFM81_024900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FFM81_024905	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FFM81_024910	COG0765	amino acid transport
FFM81_024915	COG0765	amino acid transport
FFM81_024920	COG1126	abc transporter atp-binding protein
FFM81_024935	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FFM81_024945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FFM81_024955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FFM81_024960	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FFM81_024965	COG1522	sequence-specific DNA binding
FFM81_025020	COG3961	Belongs to the TPP enzyme family
FFM81_025030	COG3920	Histidine kinase
FFM81_025035	COG3706	GGDEF domain
FFM81_025040	COG1063	alcohol dehydrogenase
FFM81_025045	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FFM81_025055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FFM81_025065	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FFM81_025070	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
FFM81_025090	COG0840	transmembrane signaling receptor activity
FFM81_025125	COG0626	cystathionine gamma-synthase activity
FFM81_025140	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FFM81_025150	COG4774	siderophore transport
FFM81_025160	COG0484	heat shock protein binding
FFM81_025170	COG2186	Transcriptional regulator
FFM81_025175	COG0747	negative chemotaxis
FFM81_025190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FFM81_025195	COG0444	Belongs to the ABC transporter superfamily
FFM81_025225	COG0405	Gamma-glutamyltransferase
FFM81_025235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFM81_025240	COG0444	Belongs to the ABC transporter superfamily
FFM81_025245	COG4608	Belongs to the ABC transporter superfamily
FFM81_025250	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FFM81_025275	COG2885	chlorophyll binding
FFM81_025280	COG0071	Belongs to the small heat shock protein (HSP20) family
FFM81_025315	COG0483	inositol monophosphate 1-phosphatase activity
FFM81_025320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FFM81_025325	COG3842	ATPase activity
FFM81_025335	COG1840	ABC-type Fe3 transport system, periplasmic component
FFM81_025340	COG1840	ABC-type Fe3 transport system, periplasmic component
FFM81_025360	COG1392	Phosphate transport regulator
FFM81_025365	COG0306	phosphate transporter
FFM81_025380	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FFM81_025385	COG3665	Urea carboxylase-associated protein
FFM81_025395	COG4770	biotin carboxylase activity
FFM81_025420	COG1116	anion transmembrane transporter activity
FFM81_025430	COG0402	S-adenosylhomocysteine deaminase activity
FFM81_025440	COG2249	NAD(P)H dehydrogenase (quinone) activity
FFM81_025450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FFM81_025455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FFM81_025460	COG1116	anion transmembrane transporter activity
FFM81_025480	COG1079	Belongs to the binding-protein-dependent transport system permease family
FFM81_025485	COG1335	isochorismatase
FFM81_025490	COG3845	ABC transporter
FFM81_025495	COG1335	isochorismatase
FFM81_025530	COG1914	H( )-stimulated, divalent metal cation uptake system
FFM81_025545	COG0477	Major facilitator Superfamily
FFM81_025560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FFM81_025570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFM81_025575	COG0601	transmembrane transport
FFM81_025590	COG2186	Transcriptional regulator
FFM81_025600	COG3395	kinase activity
FFM81_025605	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FFM81_025645	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FFM81_025665	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FFM81_025695	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FFM81_025705	COG2423	ornithine cyclodeaminase activity
FFM81_025710	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FFM81_025715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FFM81_025745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FFM81_025750	COG1522	sequence-specific DNA binding
FFM81_025755	COG0460	homoserine dehydrogenase
FFM81_025760	COG1012	belongs to the aldehyde dehydrogenase family
FFM81_025775	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FFM81_025810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FFM81_025815	COG0583	DNA-binding transcription factor activity
FFM81_025845	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FFM81_025860	COG0346	lactoylglutathione lyase activity
FFM81_025865	COG0583	DNA-binding transcription factor activity
FFM81_025870	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FFM81_025880	COG3458	cephalosporin-C deacetylase activity
FFM81_025890	COG1177	transmembrane transport
FFM81_025895	COG1176	ABC-type spermidine putrescine transport system, permease component I
FFM81_025930	COG3842	ATPase activity
FFM81_025945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FFM81_025950	COG1012	belongs to the aldehyde dehydrogenase family
FFM81_025955	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FFM81_025980	COG0405	Gamma-glutamyltransferase
FFM81_025995	COG0071	Belongs to the small heat shock protein (HSP20) family
FFM81_026010	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FFM81_026025	COG2010	Cytochrome c
FFM81_026025	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FFM81_026045	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FFM81_026050	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FFM81_026060	COG0243	molybdopterin cofactor binding
FFM81_026065	COG3685	Protein conserved in bacteria
FFM81_026110	COG0438	transferase activity, transferring glycosyl groups
FFM81_026115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFM81_026125	COG1063	alcohol dehydrogenase
FFM81_026130	COG0673	inositol 2-dehydrogenase activity
FFM81_026135	COG0531	amino acid
FFM81_026195	COG3546	catalase activity
FFM81_026200	COG3685	Protein conserved in bacteria
FFM81_026210	COG0697	spore germination
FFM81_026245	COG0492	ferredoxin-NADP+ reductase activity
FFM81_026250	COG3920	Histidine kinase
FFM81_026275	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FFM81_026280	COG0459	protein refolding
FFM81_026300	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FFM81_026320	COG4191	Histidine kinase
FFM81_026325	COG4566	intracellular signal transduction
FFM81_026335	COG0667	Aldo Keto reductase
FFM81_026340	COG0583	DNA-binding transcription factor activity
FFM81_026390	COG1396	sequence-specific DNA binding
FFM81_026410	COG3609	addiction module antidote protein, CC2985 family
FFM81_026505	COG2202	Pas domain
FFM81_026505	COG3920	Histidine kinase
FFM81_026535	COG3547	Transposase (IS116 IS110 IS902 family)
FFM81_026545	COG3547	Transposase (IS116 IS110 IS902 family)
FFM81_026565	COG1482	cell wall glycoprotein biosynthetic process
FFM81_026580	COG0459	protein refolding
FFM81_026585	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FFM81_026680	COG0492	ferredoxin-NADP+ reductase activity
FFM81_026750	COG1278	Cold shock
FFM81_026840	COG1126	abc transporter atp-binding protein
FFM81_026845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFM81_026865	COG1914	H( )-stimulated, divalent metal cation uptake system
FFM81_026900	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FFM81_026970	COG0583	DNA-binding transcription factor activity
FFM81_026990	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FFM81_027010	COG0673	inositol 2-dehydrogenase activity
FFM81_027060	COG0454	-acetyltransferase
FFM81_027060	COG0456	acetyltransferase
FFM81_027070	COG0798	PFAM Bile acid sodium symporter
FFM81_027080	COG0431	NADPH-dependent FMN reductase
FFM81_027090	COG0640	Transcriptional regulator
FFM81_027100	COG4974	Belongs to the 'phage' integrase family
FFM81_027105	COG0596	Alpha beta hydrolase
FFM81_027120	COG1335	isochorismatase
FFM81_027150	COG1902	pentaerythritol trinitrate reductase activity
FFM81_027180	COG2201	protein-glutamate methylesterase activity
FFM81_027210	COG5001	Diguanylate cyclase
FFM81_027210	COG4251	negative regulation of phosphorylation
FFM81_027210	COG3706	GGDEF domain
FFM81_027210	COG2203	Gaf domain
FFM81_027230	COG3685	Protein conserved in bacteria
FFM81_027245	COG1278	Cold shock
FFM81_027260	COG1566	PFAM secretion protein HlyD family protein
FFM81_027280	COG0668	transmembrane transport
FFM81_027295	COG0583	DNA-binding transcription factor activity
FFM81_027310	COG4948	Mandelate Racemase Muconate Lactonizing
FFM81_027325	COG0196	riboflavin kinase activity
FFM81_027350	COG0583	DNA-binding transcription factor activity
FFM81_027360	COG1012	belongs to the aldehyde dehydrogenase family
FFM81_027375	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_027395	COG1741	Belongs to the pirin family
FFM81_027400	COG1335	isochorismatase
FFM81_027405	COG0583	DNA-binding transcription factor activity
FFM81_027410	COG1073	alpha beta
FFM81_027420	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_027440	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FFM81_027455	COG2086	electron transfer activity
FFM81_027460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FFM81_027485	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FFM81_027490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FFM81_027510	COG0179	Fumarylacetoacetate (FAA) hydrolase
FFM81_027515	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FFM81_027520	COG0625	glutathione transferase activity
FFM81_027530	COG0840	transmembrane signaling receptor activity
FFM81_027560	COG1012	belongs to the aldehyde dehydrogenase family
FFM81_027590	COG0708	Exodeoxyribonuclease III
FFM81_027650	COG0270	DNA (cytosine-5-)-methyltransferase activity
FFM81_027660	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FFM81_027695	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FFM81_027735	COG0745	RESPONSE REGULATOR receiver
FFM81_027745	COG0028	Belongs to the TPP enzyme family
FFM81_027750	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FFM81_027760	COG3842	ATPase activity
FFM81_027765	COG1176	ABC-type spermidine putrescine transport system, permease component I
FFM81_027780	COG0156	8-amino-7-oxononanoate synthase activity
FFM81_027805	COG3505	Type IV secretory pathway VirD4
FFM81_027810	COG2161	toxin-antitoxin pair type II binding
FFM81_027875	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FFM81_027880	COG2948	multi-organism process
FFM81_027885	COG3504	Conjugal transfer protein
FFM81_027890	COG3736	Type IV secretory pathway, component VirB8
FFM81_027895	COG3704	protein secretion by the type IV secretion system
FFM81_027910	COG3451	type IV secretory pathway VirB4
FFM81_027915	COG3702	type iv secretory pathway
FFM81_027920	COG3838	Conjugal transfer protein Trbc
FFM81_027985	COG0673	inositol 2-dehydrogenase activity
FFM81_027995	COG1175	transmembrane transport
FFM81_028000	COG0395	ABC-type sugar transport system, permease component
FFM81_028005	COG1940	carbohydrate kinase activity
FFM81_028015	COG3842	ATPase activity
FFM81_028020	COG1192	Involved in chromosome partitioning
FFM81_028025	COG1475	DNA binding
FFM81_028030	COG1414	Transcriptional regulator
FFM81_028045	COG1609	Transcriptional regulator
FFM81_028050	COG0395	ABC-type sugar transport system, permease component
FFM81_028055	COG1175	transmembrane transport
FFM81_028070	COG3842	ATPase activity
FFM81_028080	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FFM81_028095	COG2022	thiamine diphosphate biosynthetic process
FFM81_028110	COG2274	protein secretion by the type I secretion system
FFM81_028120	COG0523	cobalamin synthesis protein
FFM81_028135	COG0523	cobalamin synthesis protein
FFM81_028150	COG1596	polysaccharide export
FFM81_028165	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FFM81_028170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFM81_028185	COG0673	inositol 2-dehydrogenase activity
FFM81_028195	COG2197	response regulator
FFM81_028205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFM81_028230	COG1215	transferase activity, transferring glycosyl groups
FFM81_028235	COG0438	transferase activity, transferring glycosyl groups
FFM81_028240	COG0297	glycogen (starch) synthase activity
FFM81_028250	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FFM81_028255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFM81_028285	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FFM81_028290	COG2323	membrane
FFM81_028310	COG4608	Belongs to the ABC transporter superfamily
FFM81_028315	COG0444	Belongs to the ABC transporter superfamily
FFM81_028320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFM81_028325	COG0601	transmembrane transport
FFM81_028330	COG0747	negative chemotaxis
FFM81_028335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FFM81_028345	COG1454	alcohol dehydrogenase
FFM81_028350	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FFM81_028405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FFM81_028410	COG1116	anion transmembrane transporter activity
FFM81_028435	COG1129	ABC transporter
FFM81_028440	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFM81_028445	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFM81_028450	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FFM81_028465	COG0395	ABC-type sugar transport system, permease component
FFM81_028475	COG3842	ATPase activity
FFM81_028480	COG3842	ATPase activity
FFM81_028500	COG1672	PFAM Archaeal ATPase
FFM81_028500	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FFM81_028510	COG0697	spore germination
FFM81_028550	COG0488	(ABC) transporter
FFM81_028625	COG1475	DNA binding
FFM81_028630	COG1192	Involved in chromosome partitioning
FFM81_028645	COG1396	sequence-specific DNA binding
FFM81_028650	COG2223	nitrite transmembrane transporter activity
FFM81_028660	COG1464	Belongs to the NlpA lipoprotein family
FFM81_028670	COG2011	ABC-type metal ion transport system permease component
FFM81_028680	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FFM81_028680	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FFM81_028690	COG0673	inositol 2-dehydrogenase activity
FFM81_028695	COG0673	inositol 2-dehydrogenase activity
FFM81_028720	COG0395	ABC-type sugar transport system, permease component
FFM81_028730	COG0667	Aldo Keto reductase
FFM81_028740	COG1294	oxidase, subunit
FFM81_028745	COG1271	oxidase subunit
FFM81_028750	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FFM81_028755	COG4988	ABC transporter
FFM81_028770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FFM81_028785	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FFM81_028795	COG1175	transmembrane transport
FFM81_028805	COG3842	ATPase activity
FFM81_028810	COG0584	glycerophosphoryl diester phosphodiesterase
FFM81_028820	COG0483	inositol monophosphate 1-phosphatase activity
FFM81_028835	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FFM81_028920	COG1573	uracil-dna glycosylase
FFM81_028940	COG2186	Transcriptional regulator
FFM81_028945	COG0626	cystathionine gamma-synthase activity
FFM81_028960	COG0395	ABC-type sugar transport system, permease component
FFM81_028965	COG3842	ATPase activity
FFM81_028980	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FFM81_028985	COG4208	sulfate ABC transporter
FFM81_028995	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FFM81_029015	COG2205	protein histidine kinase activity
FFM81_029020	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FFM81_029025	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FFM81_029030	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FFM81_029045	COG1063	alcohol dehydrogenase
FFM81_029055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FFM81_029065	COG1960	acyl-CoA dehydrogenase activity
FFM81_029115	COG1120	ATPase activity
FFM81_029125	COG1070	Carbohydrate kinase
FFM81_029140	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFM81_029150	COG1879	ABC-type sugar transport system periplasmic component
FFM81_029160	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_029160	COG3347	Dehydrogenase
FFM81_029165	COG4952	isomerase
FFM81_029170	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FFM81_029175	COG1595	DNA-templated transcription, initiation
FFM81_029180	COG3964	amidohydrolase
FFM81_029200	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_029250	COG3119	arylsulfatase activity
FFM81_029255	COG0583	DNA-binding transcription factor activity
FFM81_029290	COG0444	Belongs to the ABC transporter superfamily
FFM81_029295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFM81_029325	COG0352	thiamine-phosphate diphosphorylase activity
FFM81_029390	COG0747	negative chemotaxis
FFM81_029395	COG0601	transmembrane transport
FFM81_029410	COG1921	L-seryl-tRNASec selenium transferase activity
FFM81_029420	COG3257	ureidoglycine aminohydrolase activity
FFM81_029430	COG2186	Transcriptional regulator
FFM81_029445	COG1027	Aspartate ammonia-lyase
FFM81_029470	COG4585	Histidine kinase
FFM81_029475	COG1879	ABC-type sugar transport system periplasmic component
FFM81_029480	COG1129	ABC transporter
FFM81_029485	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFM81_029495	COG3386	PFAM SMP-30 Gluconolaconase
FFM81_029505	COG1309	transcriptional regulator
FFM81_029530	COG3485	protocatechuate 3,4-dioxygenase
FFM81_029550	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FFM81_029560	COG2814	Major facilitator Superfamily
FFM81_029580	COG0251	oxidation-reduction process
FFM81_029595	COG0395	ABC-type sugar transport system, permease component
FFM81_029600	COG1175	transmembrane transport
FFM81_029610	COG3842	ATPase activity
FFM81_029615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFM81_029620	COG2186	Transcriptional regulator
FFM81_029630	COG3273	potassium ion transport
FFM81_029630	COG0471	metal ion transport
FFM81_029680	COG0673	inositol 2-dehydrogenase activity
FFM81_029690	COG0395	ABC-type sugar transport system, permease component
FFM81_029700	COG3842	ATPase activity
FFM81_029730	COG1737	Transcriptional regulator
FFM81_029730	COG0837	glucose binding
FFM81_029735	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_029760	COG2813	Specifically methylates the guanine in position
FFM81_029770	COG4608	Belongs to the ABC transporter superfamily
FFM81_029775	COG0444	Belongs to the ABC transporter superfamily
FFM81_029780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFM81_029785	COG0601	transmembrane transport
FFM81_029800	COG3459	Glycosyltransferase 36 associated
FFM81_029805	COG2186	Transcriptional regulator
FFM81_029810	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_029815	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FFM81_029840	COG0667	Aldo Keto reductase
FFM81_029845	COG2197	response regulator
FFM81_029850	COG3842	ATPase activity
FFM81_029860	COG1176	ABC-type spermidine putrescine transport system, permease component I
FFM81_029865	COG1177	transmembrane transport
FFM81_029870	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_029880	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FFM81_029885	COG1278	Cold shock
FFM81_029905	COG2894	cell division
FFM81_029910	COG0850	regulation of cytokinetic process
FFM81_029915	COG0840	transmembrane signaling receptor activity
FFM81_029930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FFM81_029940	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FFM81_029955	COG0069	glutamate synthase activity
FFM81_029960	COG2218	PFAM glutamate synthase alpha subunit domain protein
FFM81_029965	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FFM81_029975	COG4977	sequence-specific DNA binding
FFM81_029980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FFM81_029985	COG4311	Sarcosine oxidase, delta subunit
FFM81_029990	COG0446	pyridine nucleotide-disulphide oxidoreductase
FFM81_029990	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FFM81_030000	COG2226	methyltransferase
FFM81_030005	COG1309	transcriptional regulator
FFM81_030015	COG4650	regulator
FFM81_030030	COG3038	cytochrome b561
FFM81_030035	COG1238	metal cluster binding
FFM81_030140	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_030165	COG1621	beta-fructofuranosidase activity
FFM81_030180	COG0395	ABC-type sugar transport system, permease component
FFM81_030190	COG1653	transport
FFM81_030195	COG1609	Transcriptional regulator
FFM81_030200	COG0583	DNA-binding transcription factor activity
FFM81_030210	COG0697	spore germination
FFM81_030315	COG4948	Mandelate Racemase Muconate Lactonizing
FFM81_030320	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_030335	COG1396	sequence-specific DNA binding
FFM81_030370	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FFM81_030375	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FFM81_030385	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FFM81_030405	COG1609	Transcriptional regulator
FFM81_030455	COG1192	Involved in chromosome partitioning
FFM81_030460	COG1475	DNA binding
FFM81_030465	COG1414	Transcriptional regulator
FFM81_030475	COG0670	Belongs to the BI1 family
FFM81_030510	COG4953	penicillin-binding protein 1C
FFM81_030515	COG2373	Large extracellular alpha-helical protein
FFM81_030520	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FFM81_030525	COG3034	peptidoglycan biosynthetic process
FFM81_030540	COG2814	Major facilitator Superfamily
FFM81_030550	COG1609	Transcriptional regulator
FFM81_030580	COG4941	Belongs to the sigma-70 factor family
FFM81_030585	COG1132	(ABC) transporter
FFM81_030590	COG1132	(ABC) transporter
FFM81_030595	COG0655	NAD(P)H dehydrogenase (quinone) activity
FFM81_030605	COG4191	Histidine kinase
FFM81_030605	COG0784	Response regulator, receiver
FFM81_030615	COG3346	SURF1 family
FFM81_030620	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FFM81_030625	COG1845	cytochrome c oxidase, subunit III
FFM81_030630	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FFM81_030650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FFM81_030650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FFM81_030655	COG1132	(ABC) transporter
FFM81_030690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFM81_030700	COG0747	negative chemotaxis
FFM81_030705	COG4172	Belongs to the ABC transporter superfamily
FFM81_030750	COG0596	Alpha beta hydrolase
FFM81_030775	COG1082	Xylose isomerase domain protein TIM barrel
FFM81_030775	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FFM81_030785	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FFM81_030790	COG0765	amino acid transport
FFM81_030795	COG0765	amino acid transport
FFM81_030800	COG1126	abc transporter atp-binding protein
FFM81_030805	COG0673	inositol 2-dehydrogenase activity
FFM81_030810	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FFM81_030815	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FFM81_030820	COG3485	protocatechuate 3,4-dioxygenase
FFM81_030825	COG3485	protocatechuate 3,4-dioxygenase
FFM81_030830	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FFM81_030835	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FFM81_030840	COG0583	DNA-binding transcription factor activity
FFM81_030850	COG5654	RES domain protein
FFM81_030870	COG0484	heat shock protein binding
FFM81_030880	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FFM81_030890	COG2986	histidine ammonia-lyase
FFM81_030895	COG1228	amidohydrolase
FFM81_030900	COG0402	S-adenosylhomocysteine deaminase activity
FFM81_030910	COG2188	Transcriptional regulator
FFM81_030935	COG2986	histidine ammonia-lyase
FFM81_030960	COG3119	arylsulfatase activity
FFM81_030970	COG4566	intracellular signal transduction
FFM81_030980	COG0671	phosphoesterase, PA-phosphatase related
FFM81_031025	COG1486	melibiose metabolic process
FFM81_031030	COG0747	negative chemotaxis
FFM81_031035	COG0601	transmembrane transport
FFM81_031040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFM81_031045	COG4172	Belongs to the ABC transporter superfamily
FFM81_031050	COG1486	melibiose metabolic process
FFM81_031065	COG0583	DNA-binding transcription factor activity
FFM81_031070	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_031080	COG5001	Diguanylate cyclase
FFM81_031085	COG0793	Belongs to the peptidase S41A family
FFM81_031090	COG1959	2 iron, 2 sulfur cluster binding
FFM81_031105	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FFM81_031130	COG4608	Belongs to the ABC transporter superfamily
FFM81_031140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFM81_031170	COG1414	Transcriptional regulator
FFM81_031175	COG1070	Carbohydrate kinase
FFM81_031180	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FFM81_031190	COG0022	dehydrogenase e1 component
FFM81_031195	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FFM81_031200	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFM81_031205	COG1129	ABC transporter
FFM81_031230	COG0395	ABC-type sugar transport system, permease component
FFM81_031235	COG1175	transmembrane transport
FFM81_031255	COG4211	Belongs to the binding-protein-dependent transport system permease family
FFM81_031260	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFM81_031265	COG1129	ABC transporter
FFM81_031315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FFM81_031320	COG0251	oxidation-reduction process
FFM81_031335	COG0460	homoserine dehydrogenase
FFM81_031340	COG1012	belongs to the aldehyde dehydrogenase family
FFM81_031350	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FFM81_031365	COG0765	amino acid transport
FFM81_031370	COG1126	abc transporter atp-binding protein
FFM81_031410	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FFM81_031425	COG2022	thiamine diphosphate biosynthetic process
FFM81_031490	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FFM81_031500	COG1192	Involved in chromosome partitioning
FFM81_031505	COG1475	DNA binding
FFM81_031510	COG0640	Transcriptional regulator
FFM81_031550	COG0776	regulation of translation
FFM81_031610	COG0776	regulation of translation
FFM81_031620	COG3831	ATPase activity
FFM81_031640	COG0741	lytic transglycosylase activity
FFM81_031655	COG3451	type IV secretory pathway VirB4
FFM81_031660	COG0739	heme binding
FFM81_031660	COG0741	lytic transglycosylase activity
FFM81_031660	COG1196	nuclear chromosome segregation
FFM81_031685	COG2948	multi-organism process
FFM81_031690	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FFM81_031755	COG1192	Involved in chromosome partitioning
FFM81_031790	COG2963	transposase activity
FFM81_031795	COG4974	Belongs to the 'phage' integrase family
FFM81_031800	COG4974	Belongs to the 'phage' integrase family
FFM81_031805	COG4974	Belongs to the 'phage' integrase family
FFM81_031810	COG3436	PFAM IS66 Orf2 family protein
FFM81_031815	COG4372	Transposase
FFM81_031825	COG3436	PFAM IS66 Orf2 family protein
FFM81_031980	COG1484	DNA-dependent DNA replication
FFM81_031985	COG4584	PFAM Integrase catalytic
FFM81_032090	COG5554	nitrogen fixation
FFM81_032095	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FFM81_032120	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FFM81_032125	COG2086	electron transfer activity
FFM81_032175	COG3243	poly(R)-hydroxyalkanoic acid synthase
FFM81_032185	COG1192	Involved in chromosome partitioning
FFM81_032200	COG1454	alcohol dehydrogenase
FFM81_032215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FFM81_032260	COG1129	ABC transporter
FFM81_032270	COG0559	Belongs to the binding-protein-dependent transport system permease family
FFM81_032280	COG1414	Transcriptional regulator
FFM81_032290	COG1454	alcohol dehydrogenase
FFM81_032300	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FFM81_032350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FFM81_032370	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FFM81_032375	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FFM81_032380	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FFM81_032385	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FFM81_032390	COG3383	formate dehydrogenase (NAD+) activity
FFM81_032405	COG3436	PFAM IS66 Orf2 family protein
FFM81_032495	COG3161	chorismate lyase activity
FFM81_032525	COG2801	Transposase and inactivated derivatives
FFM81_032530	COG1028	Short-chain dehydrogenase reductase Sdr
FFM81_032535	COG1028	Short-chain dehydrogenase reductase Sdr