locus-tag	class	description
FVA81_00005	COG1192	Involved in chromosome partitioning
FVA81_00010	COG1475	DNA binding
FVA81_00015	COG0640	Transcriptional regulator
FVA81_00045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FVA81_00105	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FVA81_00115	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FVA81_00135	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FVA81_00140	COG0210	DNA helicase
FVA81_00175	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FVA81_00180	COG3626	phosphonate metabolism
FVA81_00185	COG3627	carbon phosphorus lyase activity
FVA81_00190	COG4107	phosphonate C-P lyase system protein PhnK
FVA81_00195	COG4778	phosphonate C-P lyase system protein PhnL
FVA81_00210	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FVA81_00235	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FVA81_00280	COG1914	H( )-stimulated, divalent metal cation uptake system
FVA81_00285	COG0789	Transcriptional regulator
FVA81_00295	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FVA81_00315	COG3034	peptidoglycan biosynthetic process
FVA81_00320	COG2072	flavoprotein involved in K transport
FVA81_00345	COG1376	ErfK ybiS ycfS ynhG family protein
FVA81_00345	COG1388	LysM domain
FVA81_00360	COG1138	Cytochrome C-type biogenesis protein
FVA81_00370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FVA81_00395	COG4227	nucleotidyltransferase activity
FVA81_00400	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FVA81_00410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FVA81_00420	COG0745	RESPONSE REGULATOR receiver
FVA81_00485	COG0174	glutamine synthetase
FVA81_00500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FVA81_00525	COG2301	Belongs to the HpcH HpaI aldolase family
FVA81_00530	COG2030	dehydratase
FVA81_00540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FVA81_00545	COG1960	acyl-CoA dehydrogenase activity
FVA81_00570	COG2169	Transcriptional regulator
FVA81_00580	COG0183	Belongs to the thiolase family
FVA81_00585	COG1960	acyl-CoA dehydrogenase activity
FVA81_00595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FVA81_00600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FVA81_00605	COG2514	catechol 2,3-dioxygenase activity
FVA81_00620	COG1335	isochorismatase
FVA81_00635	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FVA81_00635	COG0475	glutathione-regulated potassium exporter activity
FVA81_00645	COG1733	regulation of RNA biosynthetic process
FVA81_00660	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FVA81_00665	COG2814	Major facilitator Superfamily
FVA81_00675	COG0596	Alpha beta hydrolase
FVA81_00680	COG0460	homoserine dehydrogenase
FVA81_00690	COG0251	oxidation-reduction process
FVA81_00695	COG2207	Transcriptional regulator
FVA81_00700	COG2207	Transcriptional regulator
FVA81_00705	COG1917	Cupin 2, conserved barrel domain protein
FVA81_00705	COG2207	Transcriptional regulator
FVA81_00710	COG1309	transcriptional regulator
FVA81_00715	COG0753	catalase activity
FVA81_00720	COG0400	carboxylic ester hydrolase activity
FVA81_00740	COG1335	isochorismatase
FVA81_00745	COG1741	Belongs to the pirin family
FVA81_00750	COG2388	GCN5-related N-acetyl-transferase
FVA81_00755	COG0583	DNA-binding transcription factor activity
FVA81_00775	COG1063	alcohol dehydrogenase
FVA81_00780	COG0583	DNA-binding transcription factor activity
FVA81_00785	COG0625	glutathione transferase activity
FVA81_00805	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FVA81_00810	COG0784	Response regulator, receiver
FVA81_00810	COG4191	Histidine kinase
FVA81_00835	COG3609	addiction module antidote protein, CC2985 family
FVA81_00875	COG2030	dehydratase
FVA81_00885	COG1609	Transcriptional regulator
FVA81_00890	COG3181	Tripartite tricarboxylate transporter family receptor
FVA81_00905	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FVA81_00915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FVA81_00920	COG3622	Belongs to the hyi family
FVA81_00925	COG2084	Dehydrogenase
FVA81_00930	COG1609	Transcriptional regulator
FVA81_00935	COG3395	kinase activity
FVA81_00940	COG0235	Class ii aldolase
FVA81_00945	COG0667	Aldo Keto reductase
FVA81_00965	COG1879	ABC-type sugar transport system periplasmic component
FVA81_00975	COG1172	Belongs to the binding-protein-dependent transport system permease family
FVA81_00980	COG2376	Dihydroxyacetone kinase
FVA81_00990	COG1069	ribulokinase activity
FVA81_01030	COG1396	sequence-specific DNA binding
FVA81_01035	COG3550	peptidyl-serine autophosphorylation
FVA81_01045	COG2084	Dehydrogenase
FVA81_01050	COG1063	alcohol dehydrogenase
FVA81_01100	COG1172	Belongs to the binding-protein-dependent transport system permease family
FVA81_01110	COG1129	ABC transporter
FVA81_01120	COG0776	regulation of translation
FVA81_01140	COG5001	Diguanylate cyclase
FVA81_01150	COG1278	Cold shock
FVA81_01160	COG1396	sequence-specific DNA binding
FVA81_01205	COG1126	abc transporter atp-binding protein
FVA81_01210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FVA81_01215	COG0765	amino acid transport
FVA81_01235	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_01235	COG3347	Dehydrogenase
FVA81_01270	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FVA81_01285	COG2010	Cytochrome c
FVA81_01305	COG2801	Transposase and inactivated derivatives
FVA81_01330	COG1346	cytolysis
FVA81_01345	COG5489	Protein of unknown function (DUF736)
FVA81_01350	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_01370	COG0559	Belongs to the binding-protein-dependent transport system permease family
FVA81_01400	COG5489	Protein of unknown function (DUF736)
FVA81_01410	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FVA81_01415	COG3831	ATPase activity
FVA81_01425	COG3505	Type IV secretory pathway VirD4
FVA81_01440	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FVA81_01445	COG4959	Type IV secretory pathway protease TraF
FVA81_01450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FVA81_01465	COG1968	undecaprenyl-diphosphatase activity
FVA81_01470	COG0662	Cupin 2, conserved barrel domain protein
FVA81_01470	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FVA81_01485	COG2771	luxR family
FVA81_01520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FVA81_01525	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FVA81_01535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FVA81_01540	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FVA81_01545	COG0489	protein tyrosine kinase activity
FVA81_01545	COG3206	protein involved in exopolysaccharide biosynthesis
FVA81_01560	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FVA81_01570	COG3206	protein involved in exopolysaccharide biosynthesis
FVA81_01570	COG0489	protein tyrosine kinase activity
FVA81_01580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FVA81_01585	COG0297	glycogen (starch) synthase activity
FVA81_01615	COG0110	maltose O-acetyltransferase activity
FVA81_01645	COG0583	DNA-binding transcription factor activity
FVA81_01660	COG1176	ABC-type spermidine putrescine transport system, permease component I
FVA81_01670	COG3842	ATPase activity
FVA81_01685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FVA81_01690	COG1476	TRANSCRIPTIONal
FVA81_01735	COG0318	PFAM AMP-dependent synthetase and ligase
FVA81_01755	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FVA81_01760	COG1802	Transcriptional regulator
FVA81_01765	COG3842	ATPase activity
FVA81_01770	COG1063	alcohol dehydrogenase
FVA81_01775	COG0395	ABC-type sugar transport system, permease component
FVA81_01780	COG1175	transmembrane transport
FVA81_01825	COG4604	ABC transporter, ATP-binding protein
FVA81_01830	COG4605	iron ion homeostasis
FVA81_01835	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FVA81_01855	COG1595	DNA-templated transcription, initiation
FVA81_01865	COG0483	inositol monophosphate 1-phosphatase activity
FVA81_01875	COG3842	ATPase activity
FVA81_01880	COG3833	ABC-type maltose transport systems, permease component
FVA81_01885	COG1176	ABC-type spermidine putrescine transport system, permease component I
FVA81_01895	COG1609	Transcriptional regulator
FVA81_01940	COG1312	Catalyzes the dehydration of D-mannonate
FVA81_01950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FVA81_01965	COG3485	protocatechuate 3,4-dioxygenase
FVA81_01970	COG4829	muconolactone delta-isomerase
FVA81_01995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FVA81_02000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FVA81_02010	COG3550	peptidyl-serine autophosphorylation
FVA81_02030	COG0745	RESPONSE REGULATOR receiver
FVA81_02055	COG3504	Conjugal transfer protein
FVA81_02060	COG3701	Conjugal transfer protein
FVA81_02065	COG3846	protein secretion by the type IV secretion system
FVA81_02070	COG5314	conjugation
FVA81_02075	COG3451	type IV secretory pathway VirB4
FVA81_02080	COG5268	conjugation
FVA81_02090	COG4962	Type ii secretion system protein e
FVA81_02095	COG3916	Acyl-homoserine-lactone synthase
FVA81_02100	COG1192	Involved in chromosome partitioning
FVA81_02105	COG1475	DNA binding
FVA81_02110	COG0640	Transcriptional regulator
FVA81_02135	COG1414	Transcriptional regulator
FVA81_02175	COG3177	Filamentation induced by cAMP protein fic
FVA81_02225	COG0583	DNA-binding transcription factor activity
FVA81_02245	COG4453	Protein conserved in bacteria
FVA81_02250	COG3153	acetyltransferase
FVA81_02265	COG2066	Belongs to the glutaminase family
FVA81_02275	COG0583	DNA-binding transcription factor activity
FVA81_02280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FVA81_02295	COG0747	negative chemotaxis
FVA81_02300	COG0601	transmembrane transport
FVA81_02305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FVA81_02310	COG0444	Belongs to the ABC transporter superfamily
FVA81_02315	COG4608	Belongs to the ABC transporter superfamily
FVA81_02325	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_02340	COG1280	lysine exporter protein (LysE YggA)
FVA81_02370	COG0642	Histidine kinase
FVA81_02395	COG2223	nitrite transmembrane transporter activity
FVA81_02420	COG0191	fructose-bisphosphate aldolase activity
FVA81_02430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FVA81_02435	COG3962	Belongs to the TPP enzyme family
FVA81_02440	COG0673	inositol 2-dehydrogenase activity
FVA81_02450	COG0673	inositol 2-dehydrogenase activity
FVA81_02455	COG1609	Transcriptional regulator
FVA81_02465	COG1172	Belongs to the binding-protein-dependent transport system permease family
FVA81_02505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FVA81_02525	COG4774	siderophore transport
FVA81_02540	COG1120	ATPase activity
FVA81_02545	COG1132	(ABC) transporter
FVA81_02560	COG0628	permease
FVA81_02595	COG0583	DNA-binding transcription factor activity
FVA81_02600	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FVA81_02605	COG0511	ligase activity, forming carbon-carbon bonds
FVA81_02620	COG1984	allophanate hydrolase subunit 2
FVA81_02630	COG3842	ATPase activity
FVA81_02635	COG1176	ABC-type spermidine putrescine transport system, permease component I
FVA81_02660	COG3842	ATPase activity
FVA81_02665	COG0726	polysaccharide deacetylase
FVA81_02675	COG0523	cobalamin synthesis protein
FVA81_02685	COG0154	amidase activity
FVA81_02690	COG3706	GGDEF domain
FVA81_02710	COG3842	ATPase activity
FVA81_02740	COG2010	Cytochrome c
FVA81_02810	COG2113	Glycine betaine
FVA81_02815	COG4176	ABC-type proline glycine betaine transport system permease component
FVA81_02820	COG4175	Glycine betaine
FVA81_02855	COG0583	DNA-binding transcription factor activity
FVA81_02860	COG4638	Rieske (2fe-2S)
FVA81_02865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FVA81_02870	COG1902	pentaerythritol trinitrate reductase activity
FVA81_02870	COG0446	pyridine nucleotide-disulphide oxidoreductase
FVA81_02895	COG2188	Transcriptional regulator
FVA81_02900	COG1126	abc transporter atp-binding protein
FVA81_02910	COG0765	amino acid transport
FVA81_02915	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FVA81_02915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FVA81_02920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FVA81_02925	COG3620	sequence-specific DNA binding
FVA81_02930	COG3550	peptidyl-serine autophosphorylation
FVA81_02960	COG0745	RESPONSE REGULATOR receiver
FVA81_02965	COG2202	Pas domain
FVA81_02965	COG3920	Histidine kinase
FVA81_02970	COG4544	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
FVA81_02975	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FVA81_02985	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FVA81_02990	COG2267	carboxylic ester hydrolase activity
FVA81_02995	COG0671	phosphoesterase, PA-phosphatase related
FVA81_02995	COG2453	phosphatase
FVA81_03010	COG4589	Belongs to the CDS family
FVA81_03040	COG1609	Transcriptional regulator
FVA81_03055	COG1175	transmembrane transport
FVA81_03060	COG3842	ATPase activity
FVA81_03080	COG2944	sequence-specific DNA binding
FVA81_03130	COG5001	Diguanylate cyclase
FVA81_03130	COG3300	MHYT domain
FVA81_03150	COG0840	transmembrane signaling receptor activity
FVA81_03165	COG3842	ATPase activity
FVA81_03170	COG0395	ABC-type sugar transport system, permease component
FVA81_03180	COG1653	transport
FVA81_03190	COG2186	Transcriptional regulator
FVA81_03200	COG1278	Cold shock
FVA81_03235	COG0583	DNA-binding transcription factor activity
FVA81_03265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FVA81_03270	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FVA81_03275	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FVA81_03280	COG2089	acid synthase
FVA81_03290	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FVA81_03300	COG1083	cytidylyl-transferase
FVA81_03305	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_03315	COG0107	imidazoleglycerol-phosphate synthase activity
FVA81_03375	COG2089	acid synthase
FVA81_03390	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FVA81_03395	COG1083	cytidylyl-transferase
FVA81_03410	COG0438	transferase activity, transferring glycosyl groups
FVA81_03425	COG1086	Polysaccharide biosynthesis protein
FVA81_03475	COG4948	Mandelate Racemase Muconate Lactonizing
FVA81_03490	COG0662	Cupin 2, conserved barrel domain protein
FVA81_03535	COG4221	oxidoreductase activity
FVA81_03555	COG4948	Mandelate Racemase Muconate Lactonizing
FVA81_03560	COG2186	Transcriptional regulator
FVA81_03570	COG1129	ABC transporter
FVA81_03585	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_03590	COG4191	Histidine kinase
FVA81_03595	COG4566	intracellular signal transduction
FVA81_03600	COG4566	intracellular signal transduction
FVA81_03620	COG0583	DNA-binding transcription factor activity
FVA81_03625	COG1764	response to oxidative stress
FVA81_03640	COG0477	Major facilitator Superfamily
FVA81_03650	COG4566	intracellular signal transduction
FVA81_03655	COG4191	Histidine kinase
FVA81_03700	COG1733	regulation of RNA biosynthetic process
FVA81_03725	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FVA81_03730	COG0523	cobalamin synthesis protein
FVA81_03735	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FVA81_03740	COG1121	(ABC) transporter
FVA81_03745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FVA81_03750	COG0735	belongs to the Fur family
FVA81_03770	COG1686	Belongs to the peptidase S11 family
FVA81_03795	COG0517	IMP dehydrogenase activity
FVA81_03795	COG0516	GMP reductase activity
FVA81_03800	COG1752	Esterase of the alpha-beta hydrolase superfamily
FVA81_03805	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FVA81_03810	COG0302	gtp cyclohydrolase
FVA81_03820	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FVA81_03830	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FVA81_03845	COG0778	Nitroreductase
FVA81_03865	COG0628	permease
FVA81_03870	COG0187	DNA topoisomerase II activity
FVA81_03880	COG0149	triose-phosphate isomerase activity
FVA81_03885	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FVA81_03890	COG0504	CTP synthase activity
FVA81_03895	COG0303	'Molybdopterin
FVA81_03900	COG0315	cyclic pyranopterin monophosphate synthase activity
FVA81_03905	COG0134	indole-3-glycerol-phosphate synthase activity
FVA81_03910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FVA81_03930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FVA81_03945	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FVA81_03950	COG0148	phosphopyruvate hydratase activity
FVA81_03960	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FVA81_03965	COG0508	dehydrogenase complex catalyzes the overall conversion of
FVA81_03965	COG0022	dehydrogenase e1 component
FVA81_03975	COG0508	dehydrogenase complex catalyzes the overall conversion of
FVA81_03990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FVA81_04000	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FVA81_04020	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FVA81_04020	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FVA81_04030	COG3852	Histidine kinase
FVA81_04035	COG2204	response regulator
FVA81_04040	COG5000	phosphorelay sensor kinase activity
FVA81_04045	COG2204	response regulator
FVA81_04050	COG0569	domain protein
FVA81_04060	COG1923	regulation of RNA biosynthetic process
FVA81_04065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FVA81_04075	COG3956	TIGRFAM MazG family protein
FVA81_04085	COG1648	precorrin-2 dehydrogenase activity
FVA81_04085	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FVA81_04110	COG0646	methionine synthase
FVA81_04110	COG1410	methionine synthase
FVA81_04115	COG3448	diguanylate cyclase activity
FVA81_04115	COG4175	Glycine betaine
FVA81_04130	COG1492	cobalamin metabolic process
FVA81_04200	COG0785	Cytochrome C biogenesis protein
FVA81_04205	COG0679	Auxin Efflux Carrier
FVA81_04210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FVA81_04215	COG1183	phosphatidylcholine synthase activity
FVA81_04220	COG1129	ABC transporter
FVA81_04240	COG2186	Transcriptional regulator
FVA81_04245	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FVA81_04250	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FVA81_04260	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FVA81_04270	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FVA81_04275	COG0697	spore germination
FVA81_04285	COG4166	transmembrane transport
FVA81_04305	COG0174	glutamine synthetase
FVA81_04310	COG0347	Belongs to the P(II) protein family
FVA81_04315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FVA81_04315	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FVA81_04330	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FVA81_04335	COG0629	single-stranded DNA binding
FVA81_04340	COG4325	translation initiation factor activity
FVA81_04345	COG2095	MarC family integral membrane protein
FVA81_04350	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FVA81_04355	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FVA81_04360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FVA81_04365	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FVA81_04370	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FVA81_04375	COG0343	queuine tRNA-ribosyltransferase activity
FVA81_04390	COG2801	Transposase and inactivated derivatives
FVA81_04395	COG1349	DNA-binding transcription factor activity
FVA81_04405	COG4175	Glycine betaine
FVA81_04405	COG0517	IMP dehydrogenase activity
FVA81_04410	COG4176	ABC-type proline glycine betaine transport system permease component
FVA81_04440	COG0084	hydrolase, TatD family'
FVA81_04445	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FVA81_04455	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FVA81_04460	COG1686	Belongs to the peptidase S11 family
FVA81_04485	COG2197	response regulator
FVA81_04500	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FVA81_04520	COG1653	transport
FVA81_04525	COG1175	transmembrane transport
FVA81_04530	COG0395	ABC-type sugar transport system, permease component
FVA81_04535	COG3842	ATPase activity
FVA81_04545	COG1136	(ABC) transporter
FVA81_04545	COG0577	efflux transmembrane transporter activity
FVA81_04550	COG0577	efflux transmembrane transporter activity
FVA81_04550	COG1136	(ABC) transporter
FVA81_04570	COG5598	trimethylamine methyltransferase
FVA81_04575	COG5012	cobalamin binding
FVA81_04620	COG0646	methionine synthase
FVA81_04620	COG1410	methionine synthase
FVA81_04655	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FVA81_04660	COG1309	transcriptional regulator
FVA81_04680	COG0583	DNA-binding transcription factor activity
FVA81_04710	COG1652	LysM domain
FVA81_04715	COG0730	response to heat
FVA81_04725	COG0840	transmembrane signaling receptor activity
FVA81_04730	COG1607	acyl-coa hydrolase
FVA81_04755	COG0556	nucleotide-excision repair
FVA81_04770	COG0484	heat shock protein binding
FVA81_04780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FVA81_04790	COG3246	L-lysine catabolic process to acetate
FVA81_04795	COG1250	3-hydroxyacyl-CoA dehydrogenase
FVA81_04795	COG0824	Thioesterase
FVA81_04800	COG1960	acyl-CoA dehydrogenase activity
FVA81_04805	COG1042	CoA-binding domain protein
FVA81_04805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FVA81_04805	COG0045	succinate-CoA ligase (ADP-forming) activity
FVA81_04815	COG0747	negative chemotaxis
FVA81_04820	COG0601	transmembrane transport
FVA81_04825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FVA81_04830	COG4172	Belongs to the ABC transporter superfamily
FVA81_04855	COG1760	l-serine dehydratase
FVA81_04880	COG2239	Acts as a magnesium transporter
FVA81_04885	COG0242	peptide deformylase activity
FVA81_04900	COG0321	lipoyl(octanoyl) transferase activity
FVA81_04925	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FVA81_04945	COG1671	Belongs to the UPF0178 family
FVA81_04955	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FVA81_04960	COG3507	Belongs to the glycosyl hydrolase 43 family
FVA81_04965	COG0667	Aldo Keto reductase
FVA81_04970	COG0673	inositol 2-dehydrogenase activity
FVA81_04985	COG3842	ATPase activity
FVA81_04990	COG0395	ABC-type sugar transport system, permease component
FVA81_05020	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FVA81_05085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FVA81_05090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FVA81_05095	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FVA81_05095	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FVA81_05100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FVA81_05105	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FVA81_05140	COG2099	Precorrin-6x reductase
FVA81_05150	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FVA81_05155	COG2833	Protein of unknown function (DUF455)
FVA81_05160	COG0739	heme binding
FVA81_05165	COG0513	Belongs to the DEAD box helicase family
FVA81_05180	COG2068	MobA-Related Protein
FVA81_05185	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FVA81_05185	COG3608	succinylglutamate desuccinylase aspartoacylase
FVA81_05200	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FVA81_05205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FVA81_05215	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_05235	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FVA81_05255	COG5001	Diguanylate cyclase
FVA81_05255	COG3300	MHYT domain
FVA81_05265	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FVA81_05270	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FVA81_05280	COG0047	phosphoribosylformylglycinamidine synthase activity
FVA81_05295	COG2186	Transcriptional regulator
FVA81_05300	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FVA81_05325	COG2814	Major facilitator Superfamily
FVA81_05330	COG0483	inositol monophosphate 1-phosphatase activity
FVA81_05350	COG0037	tRNA processing
FVA81_05355	COG2066	Belongs to the glutaminase family
FVA81_05360	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FVA81_05365	COG1686	Belongs to the peptidase S11 family
FVA81_05370	COG2195	Cleaves the N-terminal amino acid of tripeptides
FVA81_05380	COG2223	nitrite transmembrane transporter activity
FVA81_05390	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FVA81_05395	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FVA81_05405	COG0538	isocitrate dehydrogenase activity
FVA81_05415	COG0659	secondary active sulfate transmembrane transporter activity
FVA81_05420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FVA81_05425	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FVA81_05440	COG2313	pseudouridylate synthase activity
FVA81_05455	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FVA81_05465	COG3106	COG3106 Predicted ATPase
FVA81_05470	COG3768	UPF0283 membrane protein
FVA81_05480	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FVA81_05490	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FVA81_05500	COG0633	Ferredoxin
FVA81_05525	COG1127	ABC transporter
FVA81_05530	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FVA81_05540	COG0280	phosphate acetyltransferase
FVA81_05540	COG0281	malic enzyme
FVA81_05560	COG0778	Nitroreductase
FVA81_05565	COG0823	Involved in the tonB-independent uptake of proteins
FVA81_05580	COG1368	sulfuric ester hydrolase activity
FVA81_05595	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FVA81_05615	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FVA81_05620	COG0546	phosphoglycolate phosphatase activity
FVA81_05630	COG0114	fumarate hydratase activity
FVA81_05640	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FVA81_05640	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FVA81_05645	COG3706	GGDEF domain
FVA81_05660	COG1846	Transcriptional regulator
FVA81_05670	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FVA81_05685	COG2814	Major facilitator Superfamily
FVA81_05690	COG0746	molybdenum cofactor guanylyltransferase activity
FVA81_05695	COG1763	Mo-molybdopterin cofactor biosynthetic process
FVA81_05705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FVA81_05720	COG5425	PFAM Usg family protein
FVA81_05740	COG2084	Dehydrogenase
FVA81_05745	COG1522	sequence-specific DNA binding
FVA81_05750	COG1573	uracil-dna glycosylase
FVA81_05765	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FVA81_05770	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FVA81_05775	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FVA81_05790	COG0842	Transport permease protein
FVA81_05795	COG1131	(ABC) transporter
FVA81_05800	COG3706	GGDEF domain
FVA81_05800	COG0745	RESPONSE REGULATOR receiver
FVA81_05815	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FVA81_05815	COG3264	Mechanosensitive ion channel
FVA81_05820	COG3721	Heme iron utilization protein
FVA81_05830	COG4558	Periplasmic binding protein
FVA81_05835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FVA81_05840	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FVA81_05850	COG0384	phenazine biosynthesis protein PhzF
FVA81_05865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FVA81_05870	COG4251	negative regulation of phosphorylation
FVA81_05870	COG3706	GGDEF domain
FVA81_05870	COG2203	Gaf domain
FVA81_05870	COG5001	Diguanylate cyclase
FVA81_05875	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FVA81_05905	COG1522	sequence-specific DNA binding
FVA81_05910	COG1794	racemase activity, acting on amino acids and derivatives
FVA81_05915	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FVA81_05925	COG0789	Transcriptional regulator
FVA81_05935	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FVA81_05960	COG0656	L-ascorbic acid biosynthetic process
FVA81_05965	COG0702	epimerase
FVA81_05975	COG0640	Transcriptional regulator
FVA81_05985	COG0028	Belongs to the TPP enzyme family
FVA81_05995	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FVA81_06000	COG3830	Belongs to the UPF0237 family
FVA81_06000	COG0560	Phosphoserine phosphatase
FVA81_06010	COG3300	MHYT domain
FVA81_06010	COG5001	Diguanylate cyclase
FVA81_06025	COG0330	HflC and HflK could
FVA81_06030	COG0330	HflC and HflK could
FVA81_06040	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FVA81_06070	COG0277	FAD linked oxidase domain protein
FVA81_06075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FVA81_06100	COG1435	thymidine kinase activity
FVA81_06110	COG4993	Dehydrogenase
FVA81_06115	COG1335	isochorismatase
FVA81_06120	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FVA81_06125	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FVA81_06145	COG0006	proline dipeptidase activity
FVA81_06150	COG2264	protein methyltransferase activity
FVA81_06155	COG1999	signal sequence binding
FVA81_06165	COG0840	transmembrane signaling receptor activity
FVA81_06170	COG0835	chemotaxis
FVA81_06185	COG2176	DNA-directed DNA polymerase activity
FVA81_06205	COG3706	GGDEF domain
FVA81_06210	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FVA81_06230	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FVA81_06240	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FVA81_06245	COG0849	cell division
FVA81_06250	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FVA81_06255	COG1181	Belongs to the D-alanine--D-alanine ligase family
FVA81_06260	COG3706	GGDEF domain
FVA81_06265	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FVA81_06270	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FVA81_06275	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FVA81_06285	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FVA81_06290	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FVA81_06300	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FVA81_06310	COG5462	secreted (periplasmic) protein
FVA81_06315	COG0275	rRNA processing
FVA81_06320	COG2001	Belongs to the MraZ family
FVA81_06335	COG0741	lytic transglycosylase activity
FVA81_06335	COG1196	nuclear chromosome segregation
FVA81_06335	COG0739	heme binding
FVA81_06340	COG3023	N-Acetylmuramoyl-L-alanine amidase
FVA81_06345	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FVA81_06370	COG5001	Diguanylate cyclase
FVA81_06380	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FVA81_06400	COG0640	Transcriptional regulator
FVA81_06420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FVA81_06425	COG0028	Belongs to the TPP enzyme family
FVA81_06450	COG1376	ErfK ybiS ycfS ynhG family protein
FVA81_06480	COG0174	glutamine synthetase
FVA81_06485	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FVA81_06520	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FVA81_06555	COG2968	Membrane
FVA81_06565	COG0582	viral genome integration into host DNA
FVA81_06570	COG1002	Type II restriction enzyme, methylase subunits
FVA81_06605	COG1403	HNH endonuclease
FVA81_06620	COG0515	serine threonine protein kinase
FVA81_06620	COG2815	serine threonine protein kinase
FVA81_06625	COG0631	protein serine/threonine phosphatase activity
FVA81_06635	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FVA81_06640	COG1368	sulfuric ester hydrolase activity
FVA81_06670	COG1522	sequence-specific DNA binding
FVA81_06680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FVA81_06685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FVA81_06690	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FVA81_06695	COG2423	ornithine cyclodeaminase activity
FVA81_06700	COG0006	proline dipeptidase activity
FVA81_06705	COG3608	succinylglutamate desuccinylase aspartoacylase
FVA81_06710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FVA81_06715	COG0765	amino acid transport
FVA81_06720	COG0765	amino acid transport
FVA81_06725	COG1126	abc transporter atp-binding protein
FVA81_06740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FVA81_06755	COG1012	belongs to the aldehyde dehydrogenase family
FVA81_06760	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FVA81_06765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FVA81_06770	COG0765	amino acid transport
FVA81_06795	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FVA81_06800	COG1473	amidohydrolase
FVA81_06805	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FVA81_06815	COG3842	ATPase activity
FVA81_06825	COG1176	ABC-type spermidine putrescine transport system, permease component I
FVA81_06835	COG1609	Transcriptional regulator
FVA81_06840	COG0402	S-adenosylhomocysteine deaminase activity
FVA81_06855	COG1116	anion transmembrane transporter activity
FVA81_06890	COG0747	negative chemotaxis
FVA81_06895	COG0601	transmembrane transport
FVA81_06905	COG0405	Gamma-glutamyltransferase
FVA81_06915	COG4172	Belongs to the ABC transporter superfamily
FVA81_06925	COG0438	transferase activity, transferring glycosyl groups
FVA81_06945	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FVA81_06955	COG1116	anion transmembrane transporter activity
FVA81_06960	COG2011	ABC-type metal ion transport system permease component
FVA81_06980	COG0745	RESPONSE REGULATOR receiver
FVA81_06995	COG0747	negative chemotaxis
FVA81_07010	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FVA81_07015	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FVA81_07020	COG2080	2 iron, 2 sulfur cluster binding
FVA81_07055	COG0432	Pfam Uncharacterised protein family UPF0047
FVA81_07060	COG4702	Belongs to the UPF0303 family
FVA81_07080	COG1473	amidohydrolase
FVA81_07100	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FVA81_07110	COG0358	DNA primase activity
FVA81_07120	COG0505	Belongs to the CarA family
FVA81_07125	COG0534	Mate efflux family protein
FVA81_07135	COG2321	neutral zinc metallopeptidase
FVA81_07155	COG0840	transmembrane signaling receptor activity
FVA81_07170	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FVA81_07200	COG0477	Major facilitator Superfamily
FVA81_07205	COG1573	uracil-dna glycosylase
FVA81_07215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FVA81_07230	COG1522	sequence-specific DNA binding
FVA81_07235	COG0492	ferredoxin-NADP+ reductase activity
FVA81_07250	COG1902	pentaerythritol trinitrate reductase activity
FVA81_07260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FVA81_07275	COG0387	Pfam Sodium calcium exchanger
FVA81_07285	COG2133	pyrroloquinoline quinone binding
FVA81_07300	COG0446	pyridine nucleotide-disulphide oxidoreductase
FVA81_07305	COG2133	pyrroloquinoline quinone binding
FVA81_07310	COG1278	Cold shock
FVA81_07320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FVA81_07325	COG1846	Transcriptional regulator
FVA81_07330	COG0745	RESPONSE REGULATOR receiver
FVA81_07335	COG2205	protein histidine kinase activity
FVA81_07340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FVA81_07360	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FVA81_07385	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FVA81_07400	COG1012	belongs to the aldehyde dehydrogenase family
FVA81_07410	COG3300	MHYT domain
FVA81_07410	COG5001	Diguanylate cyclase
FVA81_07415	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FVA81_07430	COG0193	aminoacyl-tRNA hydrolase activity
FVA81_07435	COG2890	protein-(glutamine-N5) methyltransferase activity
FVA81_07440	COG1959	2 iron, 2 sulfur cluster binding
FVA81_07445	COG2267	carboxylic ester hydrolase activity
FVA81_07455	COG0251	oxidation-reduction process
FVA81_07460	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FVA81_07465	COG0012	GTP binding
FVA81_07490	COG0386	Belongs to the glutathione peroxidase family
FVA81_07500	COG1280	lysine exporter protein (LysE YggA)
FVA81_07505	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FVA81_07510	COG2857	Cytochrome c1
FVA81_07510	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FVA81_07525	COG1132	(ABC) transporter
FVA81_07545	COG2972	Histidine kinase
FVA81_07545	COG0840	transmembrane signaling receptor activity
FVA81_07550	COG1132	(ABC) transporter
FVA81_07555	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FVA81_07575	COG0408	coproporphyrinogen oxidase activity
FVA81_07590	COG0617	tRNA 3'-terminal CCA addition
FVA81_07605	COG0714	Associated with various cellular activities
FVA81_07630	COG0454	-acetyltransferase
FVA81_07640	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FVA81_07650	COG0435	Glutathione S-transferase
FVA81_07670	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FVA81_07680	COG3135	benzoate transporter
FVA81_07685	COG3706	GGDEF domain
FVA81_07690	COG0019	diaminopimelate decarboxylase activity
FVA81_07705	COG0583	DNA-binding transcription factor activity
FVA81_07715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FVA81_07760	COG2963	transposase activity
FVA81_07765	COG3436	PFAM IS66 Orf2 family protein
FVA81_07770	COG4372	Transposase
FVA81_07815	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FVA81_07830	COG0395	ABC-type sugar transport system, permease component
FVA81_07840	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FVA81_07845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FVA81_07855	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_07860	COG1063	alcohol dehydrogenase
FVA81_07865	COG1609	Transcriptional regulator
FVA81_07880	COG0434	BtpA family
FVA81_07895	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FVA81_07900	COG1172	Belongs to the binding-protein-dependent transport system permease family
FVA81_07910	COG1879	ABC-type sugar transport system periplasmic component
FVA81_07915	COG1609	Transcriptional regulator
FVA81_07940	COG0740	serine-type endopeptidase activity
FVA81_07945	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FVA81_08010	COG1132	(ABC) transporter
FVA81_08025	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FVA81_08040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FVA81_08050	COG1126	abc transporter atp-binding protein
FVA81_08060	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FVA81_08065	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FVA81_08080	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FVA81_08080	COG0512	Glutamine amidotransferase of anthranilate synthase
FVA81_08090	COG4771	TonB-dependent receptor
FVA81_08095	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FVA81_08110	COG2207	Transcriptional regulator
FVA81_08115	COG0506	proline dehydrogenase activity
FVA81_08115	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FVA81_08115	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FVA81_08125	COG2197	response regulator
FVA81_08175	COG4175	Glycine betaine
FVA81_08235	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FVA81_08255	COG0366	Alpha amylase catalytic
FVA81_08265	COG1160	GTP binding
FVA81_08285	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FVA81_08300	COG0024	Methionine aminopeptidase
FVA81_08305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FVA81_08310	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_08320	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FVA81_08335	COG0583	DNA-binding transcription factor activity
FVA81_08345	COG0402	S-adenosylhomocysteine deaminase activity
FVA81_08360	COG1304	FMN binding
FVA81_08370	COG2351	hydroxyisourate hydrolase activity
FVA81_08375	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FVA81_08390	COG0174	glutamine synthetase
FVA81_08400	COG4266	Belongs to the allantoicase family
FVA81_08405	COG3648	Uricase
FVA81_08405	COG3195	allantoin biosynthetic process
FVA81_08410	COG1064	alcohol dehydrogenase
FVA81_08430	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FVA81_08440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FVA81_08440	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FVA81_08445	COG0784	Response regulator, receiver
FVA81_08445	COG2205	protein histidine kinase activity
FVA81_08445	COG5002	protein histidine kinase activity
FVA81_08450	COG5598	trimethylamine methyltransferase
FVA81_08465	COG4335	DNA alkylation repair
FVA81_08475	COG0513	Belongs to the DEAD box helicase family
FVA81_08485	COG2308	Evidence 4 Homologs of previously reported genes of
FVA81_08495	COG1305	Transglutaminase-like
FVA81_08550	COG0488	(ABC) transporter
FVA81_08555	COG2346	COG2346, Truncated hemoglobins
FVA81_08580	COG0493	'glutamate synthase
FVA81_08595	COG3932	Exopolysaccharide synthesis, ExoD
FVA81_08605	COG1309	transcriptional regulator
FVA81_08645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FVA81_08650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FVA81_08655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FVA81_08675	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FVA81_08680	COG0830	nickel cation binding
FVA81_08685	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FVA81_08690	COG3706	GGDEF domain
FVA81_08700	COG0804	urea catabolic process
FVA81_08705	COG1442	glycosyl transferase family 8
FVA81_08710	COG3755	Protein conserved in bacteria
FVA81_08715	COG0832	Belongs to the urease beta subunit family
FVA81_08720	COG3813	Protein conserved in bacteria
FVA81_08725	COG0831	urea catabolic process
FVA81_08730	COG0829	nickel cation binding
FVA81_08755	COG0559	Belongs to the binding-protein-dependent transport system permease family
FVA81_08770	COG4251	negative regulation of phosphorylation
FVA81_08780	COG2205	protein histidine kinase activity
FVA81_08780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FVA81_08795	COG0683	leucine binding
FVA81_08810	COG0411	ABC transporter
FVA81_08835	COG1408	metallophosphoesterase
FVA81_08845	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FVA81_08845	COG0446	pyridine nucleotide-disulphide oxidoreductase
FVA81_08850	COG4311	Sarcosine oxidase, delta subunit
FVA81_08855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FVA81_08870	COG2197	response regulator
FVA81_08920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FVA81_08930	COG0564	pseudouridine synthase activity
FVA81_08940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FVA81_08950	COG1131	(ABC) transporter
FVA81_08960	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FVA81_08965	COG0697	spore germination
FVA81_08970	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FVA81_08995	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FVA81_09005	COG0586	Pfam SNARE associated Golgi protein
FVA81_09015	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FVA81_09025	COG0346	lactoylglutathione lyase activity
FVA81_09040	COG4191	Histidine kinase
FVA81_09045	COG2204	response regulator
FVA81_09050	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FVA81_09065	COG4948	Mandelate Racemase Muconate Lactonizing
FVA81_09070	COG0482	sulfurtransferase activity
FVA81_09090	COG0673	inositol 2-dehydrogenase activity
FVA81_09105	COG1294	oxidase, subunit
FVA81_09110	COG1271	oxidase subunit
FVA81_09115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FVA81_09135	COG0840	transmembrane signaling receptor activity
FVA81_09140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FVA81_09145	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FVA81_09160	COG0632	four-way junction helicase activity
FVA81_09175	COG2255	four-way junction helicase activity
FVA81_09180	COG0494	nUDIX hydrolase
FVA81_09185	COG2318	DinB family
FVA81_09195	COG0824	Thioesterase
FVA81_09215	COG0823	Involved in the tonB-independent uptake of proteins
FVA81_09220	COG2885	chlorophyll binding
FVA81_09230	COG0037	tRNA processing
FVA81_09235	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FVA81_09240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FVA81_09245	COG0217	transcriptional regulatory protein
FVA81_09260	COG1692	metallophosphoesterase
FVA81_09265	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FVA81_09300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FVA81_09305	COG3263	regulation of cellular component size
FVA81_09310	COG0126	phosphoglycerate kinase activity
FVA81_09315	COG3588	fructose-bisphosphate aldolase
FVA81_09320	COG0384	phenazine biosynthesis protein PhzF
FVA81_09350	COG0254	rRNA binding
FVA81_09355	COG1132	(ABC) transporter
FVA81_09365	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FVA81_09365	COG2885	chlorophyll binding
FVA81_09375	COG0483	inositol monophosphate 1-phosphatase activity
FVA81_09380	COG3174	membrane
FVA81_09400	COG0640	Transcriptional regulator
FVA81_09415	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FVA81_09420	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FVA81_09425	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FVA81_09430	COG0457	Tetratricopeptide repeat
FVA81_09440	COG0469	pyruvate kinase activity
FVA81_09460	COG3750	Belongs to the UPF0335 family
FVA81_09480	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FVA81_09480	COG0512	Glutamine amidotransferase of anthranilate synthase
FVA81_09495	COG4221	oxidoreductase activity
FVA81_09500	COG0583	DNA-binding transcription factor activity
FVA81_09510	COG5310	Homospermidine synthase
FVA81_09520	COG0737	Belongs to the 5'-nucleotidase family
FVA81_09525	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FVA81_09540	COG0330	HflC and HflK could
FVA81_09550	COG0517	IMP dehydrogenase activity
FVA81_09550	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FVA81_09560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FVA81_09565	COG2951	lytic endotransglycosylase activity
FVA81_09580	COG0070	glutamate synthase
FVA81_09580	COG0069	glutamate synthase activity
FVA81_09580	COG0067	glutamate synthase
FVA81_09595	COG3220	belongs to the UPF0276 family
FVA81_09610	COG0071	Belongs to the small heat shock protein (HSP20) family
FVA81_09650	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FVA81_09650	COG0662	Cupin 2, conserved barrel domain protein
FVA81_09660	COG2308	Evidence 4 Homologs of previously reported genes of
FVA81_09660	COG2307	Protein conserved in bacteria
FVA81_09675	COG0058	SHG alpha-glucan phosphorylase activity
FVA81_09680	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FVA81_09685	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FVA81_09690	COG0297	glycogen (starch) synthase activity
FVA81_09695	COG0033	Phosphoglucomutase
FVA81_09710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FVA81_09720	COG0431	NADPH-dependent FMN reductase
FVA81_09755	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FVA81_09755	COG0446	pyridine nucleotide-disulphide oxidoreductase
FVA81_09765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FVA81_09770	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FVA81_09790	COG3300	MHYT domain
FVA81_09790	COG5001	Diguanylate cyclase
FVA81_09800	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FVA81_09805	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FVA81_09815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FVA81_09820	COG1609	Transcriptional regulator
FVA81_09825	COG1846	Transcriptional regulator
FVA81_09835	COG0523	cobalamin synthesis protein
FVA81_09845	COG0840	transmembrane signaling receptor activity
FVA81_09845	COG2972	Histidine kinase
FVA81_09865	COG0583	DNA-binding transcription factor activity
FVA81_09895	COG0800	Aldolase
FVA81_09920	COG5001	Diguanylate cyclase
FVA81_09925	COG0778	Nitroreductase
FVA81_09930	COG1733	regulation of RNA biosynthetic process
FVA81_09940	COG0673	inositol 2-dehydrogenase activity
FVA81_09955	COG1879	ABC-type sugar transport system periplasmic component
FVA81_09960	COG1172	Belongs to the binding-protein-dependent transport system permease family
FVA81_09965	COG1129	ABC transporter
FVA81_09970	COG1609	Transcriptional regulator
FVA81_09980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FVA81_09985	COG2115	Belongs to the xylose isomerase family
FVA81_09990	COG1070	Carbohydrate kinase
FVA81_09995	COG1609	Transcriptional regulator
FVA81_10010	COG1309	transcriptional regulator
FVA81_10015	COG1253	flavin adenine dinucleotide binding
FVA81_10020	COG0471	metal ion transport
FVA81_10020	COG3273	potassium ion transport
FVA81_10025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FVA81_10030	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FVA81_10050	COG1121	(ABC) transporter
FVA81_10055	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FVA81_10060	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FVA81_10070	COG0697	spore germination
FVA81_10075	COG0583	DNA-binding transcription factor activity
FVA81_10080	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FVA81_10085	COG3842	ATPase activity
FVA81_10090	COG1176	ABC-type spermidine putrescine transport system, permease component I
FVA81_10095	COG1177	transmembrane transport
FVA81_10120	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FVA81_10130	COG3668	Plasmid stabilization system
FVA81_10140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FVA81_10160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FVA81_10170	COG4172	Belongs to the ABC transporter superfamily
FVA81_10175	COG1473	amidohydrolase
FVA81_10185	COG0601	transmembrane transport
FVA81_10190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FVA81_10195	COG0671	phosphoesterase, PA-phosphatase related
FVA81_10210	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FVA81_10220	COG0154	amidase activity
FVA81_10225	COG3842	ATPase activity
FVA81_10230	COG1176	ABC-type spermidine putrescine transport system, permease component I
FVA81_10235	COG1177	transmembrane transport
FVA81_10250	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FVA81_10265	COG3618	amidohydrolase
FVA81_10275	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_10290	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FVA81_10350	COG0784	Response regulator, receiver
FVA81_10370	COG3237	CsbD-like
FVA81_10395	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FVA81_10400	COG1024	Enoyl-CoA hydratase
FVA81_10415	COG0640	Transcriptional regulator
FVA81_10420	COG1396	sequence-specific DNA binding
FVA81_10420	COG3800	Transcriptional regulator
FVA81_10425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FVA81_10430	COG0625	glutathione transferase activity
FVA81_10460	COG1176	ABC-type spermidine putrescine transport system, permease component I
FVA81_10465	COG3842	ATPase activity
FVA81_10480	COG0583	DNA-binding transcription factor activity
FVA81_10500	COG3718	enzyme involved in inositol metabolism
FVA81_10515	COG3962	Belongs to the TPP enzyme family
FVA81_10520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FVA81_10530	COG0673	inositol 2-dehydrogenase activity
FVA81_10535	COG0673	inositol 2-dehydrogenase activity
FVA81_10545	COG1609	Transcriptional regulator
FVA81_10580	COG0745	RESPONSE REGULATOR receiver
FVA81_10615	COG0840	transmembrane signaling receptor activity
FVA81_10615	COG2972	Histidine kinase
FVA81_10625	COG3002	Belongs to the UPF0753 family
FVA81_10630	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FVA81_10650	COG1595	DNA-templated transcription, initiation
FVA81_10660	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FVA81_10665	COG3485	protocatechuate 3,4-dioxygenase
FVA81_10670	COG3485	protocatechuate 3,4-dioxygenase
FVA81_10675	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FVA81_10680	COG2267	carboxylic ester hydrolase activity
FVA81_10685	COG0583	DNA-binding transcription factor activity
FVA81_10690	COG1414	Transcriptional regulator
FVA81_10700	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FVA81_10715	COG5001	Diguanylate cyclase
FVA81_10715	COG3300	MHYT domain
FVA81_10720	COG3142	Participates in the control of copper homeostasis
FVA81_10740	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_10745	COG1737	Transcriptional regulator
FVA81_10775	COG3842	ATPase activity
FVA81_10785	COG0395	ABC-type sugar transport system, permease component
FVA81_10790	COG1175	transmembrane transport
FVA81_10795	COG0673	inositol 2-dehydrogenase activity
FVA81_10805	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FVA81_10810	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FVA81_10815	COG1940	carbohydrate kinase activity
FVA81_10835	COG3833	ABC-type maltose transport systems, permease component
FVA81_10840	COG1176	ABC-type spermidine putrescine transport system, permease component I
FVA81_10850	COG3842	ATPase activity
FVA81_10860	COG2186	Transcriptional regulator
FVA81_10865	COG1172	Belongs to the binding-protein-dependent transport system permease family
FVA81_10870	COG1172	Belongs to the binding-protein-dependent transport system permease family
FVA81_10875	COG1129	ABC transporter
FVA81_10880	COG1879	ABC-type sugar transport system periplasmic component
FVA81_10890	COG2197	response regulator
FVA81_10895	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FVA81_10910	COG0662	Cupin 2, conserved barrel domain protein
FVA81_10910	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FVA81_10960	COG0835	chemotaxis
FVA81_10975	COG0640	Transcriptional regulator
FVA81_10985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FVA81_10990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FVA81_11000	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
FVA81_11010	COG1233	COG1233 Phytoene dehydrogenase and related
FVA81_11015	COG1562	ergosterol biosynthetic process
FVA81_11030	COG0142	geranyltranstransferase activity
FVA81_11040	COG1063	alcohol dehydrogenase
FVA81_11045	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
FVA81_11050	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FVA81_11055	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FVA81_11090	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FVA81_11095	COG0156	8-amino-7-oxononanoate synthase activity
FVA81_11105	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FVA81_11140	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
FVA81_11145	COG1429	ligase activity, forming nitrogen-metal bonds
FVA81_11150	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FVA81_11155	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FVA81_11175	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FVA81_11180	COG2211	Major facilitator Superfamily
FVA81_11185	COG0644	oxidoreductase
FVA81_11190	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FVA81_11200	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FVA81_11210	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FVA81_11230	COG4989	oxidoreductase activity
FVA81_11250	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FVA81_11255	COG2855	membrane
FVA81_11265	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FVA81_11270	COG2218	PFAM glutamate synthase alpha subunit domain protein
FVA81_11275	COG0069	glutamate synthase activity
FVA81_11300	COG1653	transport
FVA81_11310	COG0673	inositol 2-dehydrogenase activity
FVA81_11315	COG1609	Transcriptional regulator
FVA81_11335	COG1172	Belongs to the binding-protein-dependent transport system permease family
FVA81_11340	COG1129	ABC transporter
FVA81_11345	COG1879	ABC-type sugar transport system periplasmic component
FVA81_11355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FVA81_11360	COG1129	ABC transporter
FVA81_11365	COG1172	Belongs to the binding-protein-dependent transport system permease family
FVA81_11375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FVA81_11380	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FVA81_11390	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FVA81_11405	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FVA81_11410	COG1309	transcriptional regulator
FVA81_11415	COG4952	isomerase
FVA81_11420	COG3347	Dehydrogenase
FVA81_11420	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_11435	COG1129	ABC transporter
FVA81_11440	COG1172	Belongs to the binding-protein-dependent transport system permease family
FVA81_11445	COG1172	Belongs to the binding-protein-dependent transport system permease family
FVA81_11450	COG3254	rhamnose metabolic process
FVA81_11465	COG4774	siderophore transport
FVA81_11470	COG4592	Periplasmic binding protein
FVA81_11475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FVA81_11480	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FVA81_11485	COG1120	ATPase activity
FVA81_11500	COG3842	ATPase activity
FVA81_11510	COG1840	ABC-type Fe3 transport system, periplasmic component
FVA81_11515	COG1840	ABC-type Fe3 transport system, periplasmic component
FVA81_11520	COG0745	RESPONSE REGULATOR receiver
FVA81_11535	COG3706	GGDEF domain
FVA81_11550	COG1172	Belongs to the binding-protein-dependent transport system permease family
FVA81_11560	COG1609	Transcriptional regulator
FVA81_11565	COG3386	PFAM SMP-30 Gluconolaconase
FVA81_11570	COG1063	alcohol dehydrogenase
FVA81_11575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FVA81_11580	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_11585	COG3265	gluconokinase activity
FVA81_11590	COG2084	Dehydrogenase
FVA81_11600	COG1609	Transcriptional regulator
FVA81_11605	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FVA81_11610	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FVA81_11615	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FVA81_11620	COG1609	Transcriptional regulator
FVA81_11625	COG1309	transcriptional regulator
FVA81_11635	COG1115	amino acid carrier protein
FVA81_11640	COG2337	Toxic component of a toxin-antitoxin (TA) module
FVA81_11675	COG4372	Transposase
FVA81_11745	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FVA81_11760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FVA81_11770	COG0789	Transcriptional regulator
FVA81_11775	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FVA81_11785	COG0583	DNA-binding transcription factor activity
FVA81_11795	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FVA81_11800	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FVA81_11810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FVA81_11820	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FVA81_11870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FVA81_11875	COG1012	belongs to the aldehyde dehydrogenase family
FVA81_11890	COG0848	biopolymer transport protein
FVA81_11905	COG0307	riboflavin synthase, alpha
FVA81_11925	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_11945	COG1960	acyl-CoA dehydrogenase activity
FVA81_11955	COG2373	Large extracellular alpha-helical protein
FVA81_11960	COG4953	penicillin-binding protein 1C
FVA81_12010	COG0670	Belongs to the BI1 family
FVA81_12030	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FVA81_12045	COG2197	response regulator
FVA81_12050	COG0697	spore germination
FVA81_12055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FVA81_12060	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FVA81_12065	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FVA81_12080	COG0277	FAD linked oxidase domain protein
FVA81_12085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FVA81_12090	COG2084	Dehydrogenase
FVA81_12095	COG0129	dihydroxy-acid dehydratase activity
FVA81_12105	COG0784	Response regulator, receiver
FVA81_12110	COG0784	Response regulator, receiver
FVA81_12110	COG4191	Histidine kinase
FVA81_12135	COG2176	DNA-directed DNA polymerase activity
FVA81_12135	COG5002	protein histidine kinase activity
FVA81_12145	COG0517	IMP dehydrogenase activity
FVA81_12150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FVA81_12160	COG1215	transferase activity, transferring glycosyl groups
FVA81_12195	COG0583	DNA-binding transcription factor activity
FVA81_12205	COG1116	anion transmembrane transporter activity
FVA81_12210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FVA81_12215	COG0402	S-adenosylhomocysteine deaminase activity
FVA81_12225	COG2249	NAD(P)H dehydrogenase (quinone) activity
FVA81_12230	COG0251	oxidation-reduction process
FVA81_12265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FVA81_12270	COG4172	Belongs to the ABC transporter superfamily
FVA81_12280	COG0601	transmembrane transport
FVA81_12285	COG0747	negative chemotaxis
FVA81_12300	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FVA81_12305	COG1454	alcohol dehydrogenase
FVA81_12310	COG2186	Transcriptional regulator
FVA81_12315	COG3395	kinase activity
FVA81_12325	COG4136	ATPase activity
FVA81_12330	COG4135	transport system, permease component
FVA81_12335	COG4134	Bacterial extracellular solute-binding protein
FVA81_12345	COG0398	Pfam SNARE associated Golgi protein
FVA81_12355	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FVA81_12365	COG0405	Gamma-glutamyltransferase
FVA81_12370	COG0583	DNA-binding transcription factor activity
FVA81_12375	COG3485	protocatechuate 3,4-dioxygenase
FVA81_12405	COG4177	L-phenylalanine transmembrane transporter activity
FVA81_12415	COG3485	protocatechuate 3,4-dioxygenase
FVA81_12435	COG0583	DNA-binding transcription factor activity
FVA81_12455	COG0438	transferase activity, transferring glycosyl groups
FVA81_12465	COG0489	protein tyrosine kinase activity
FVA81_12465	COG3206	protein involved in exopolysaccharide biosynthesis
FVA81_12500	COG1442	glycosyl transferase family 8
FVA81_12510	COG2197	response regulator
FVA81_12550	COG4608	Belongs to the ABC transporter superfamily
FVA81_12555	COG0444	Belongs to the ABC transporter superfamily
FVA81_12560	COG0601	transmembrane transport
FVA81_12565	COG0747	negative chemotaxis
FVA81_12570	COG1363	Peptidase, m42
FVA81_12575	COG0583	DNA-binding transcription factor activity
FVA81_12585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FVA81_12595	COG1278	Cold shock
FVA81_12605	COG3842	ATPase activity
FVA81_12610	COG3842	ATPase activity
FVA81_12620	COG0395	ABC-type sugar transport system, permease component
FVA81_12635	COG1609	Transcriptional regulator
FVA81_12670	COG2186	Transcriptional regulator
FVA81_12675	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FVA81_12685	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FVA81_12690	COG1063	alcohol dehydrogenase
FVA81_12695	COG1312	Catalyzes the dehydration of D-mannonate
FVA81_12700	COG0246	Mannitol dehydrogenase
FVA81_12705	COG1802	Transcriptional regulator
FVA81_12715	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FVA81_12730	COG0601	transmembrane transport
FVA81_12735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FVA81_12740	COG0444	Belongs to the ABC transporter superfamily
FVA81_12745	COG4608	Belongs to the ABC transporter superfamily
FVA81_12755	COG0402	S-adenosylhomocysteine deaminase activity
FVA81_12765	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_12770	COG2186	Transcriptional regulator
FVA81_12780	COG0765	amino acid transport
FVA81_12785	COG1126	abc transporter atp-binding protein
FVA81_12810	COG0559	Belongs to the binding-protein-dependent transport system permease family
FVA81_12820	COG0411	ABC transporter
FVA81_12825	COG1802	Transcriptional regulator
FVA81_12840	COG0683	leucine binding
FVA81_12890	COG1196	nuclear chromosome segregation
FVA81_12890	COG0739	heme binding
FVA81_12890	COG0741	lytic transglycosylase activity
FVA81_12895	COG0542	response to heat
FVA81_12905	COG2890	protein-(glutamine-N5) methyltransferase activity
FVA81_12910	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FVA81_12920	COG0527	aspartate kinase activity
FVA81_12925	COG0392	lysyltransferase activity
FVA81_12925	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FVA81_12940	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FVA81_12960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FVA81_12970	COG1040	competence protein
FVA81_12975	COG2226	methyltransferase
FVA81_12990	COG0494	nUDIX hydrolase
FVA81_12995	COG0456	acetyltransferase
FVA81_12995	COG0454	-acetyltransferase
FVA81_13000	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FVA81_13005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FVA81_13010	COG0653	protein targeting
FVA81_13025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FVA81_13060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FVA81_13070	COG0300	oxidoreductase activity
FVA81_13090	COG2086	electron transfer activity
FVA81_13095	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FVA81_13100	COG1250	3-hydroxyacyl-CoA dehydrogenase
FVA81_13105	COG4150	thiosulfate binding
FVA81_13115	COG4208	sulfate ABC transporter
FVA81_13120	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FVA81_13125	COG2200	EAL domain
FVA81_13130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FVA81_13135	COG0165	Argininosuccinate lyase
FVA81_13170	COG2884	Cell division ATP-binding protein ftsE
FVA81_13190	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FVA81_13200	COG0287	Prephenate dehydrogenase
FVA81_13205	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FVA81_13210	COG2226	methyltransferase
FVA81_13215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FVA81_13240	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FVA81_13245	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FVA81_13275	COG4536	flavin adenine dinucleotide binding
FVA81_13280	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FVA81_13285	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FVA81_13290	COG4974	Belongs to the 'phage' integrase family
FVA81_13295	COG0825	malonyl-CoA metabolic process
FVA81_13300	COG3034	peptidoglycan biosynthetic process
FVA81_13305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FVA81_13305	COG0425	Belongs to the sulfur carrier protein TusA family
FVA81_13310	COG0523	cobalamin synthesis protein
FVA81_13315	COG1686	Belongs to the peptidase S11 family
FVA81_13320	COG1473	amidohydrolase
FVA81_13365	COG3685	Protein conserved in bacteria
FVA81_13380	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FVA81_13390	COG0156	8-amino-7-oxononanoate synthase activity
FVA81_13415	COG0729	surface antigen
FVA81_13440	COG0835	chemotaxis
FVA81_13445	COG0252	asparaginase activity
FVA81_13460	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FVA81_13465	COG3383	formate dehydrogenase (NAD+) activity
FVA81_13480	COG0583	DNA-binding transcription factor activity
FVA81_13490	COG0039	L-malate dehydrogenase activity
FVA81_13500	COG1012	belongs to the aldehyde dehydrogenase family
FVA81_13505	COG4948	Mandelate Racemase Muconate Lactonizing
FVA81_13510	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FVA81_13515	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FVA81_13520	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FVA81_13525	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FVA81_13530	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FVA81_13535	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FVA81_13555	COG4974	Belongs to the 'phage' integrase family
FVA81_13580	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_13595	COG0508	dehydrogenase complex catalyzes the overall conversion of
FVA81_13605	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FVA81_13610	COG0045	succinate-CoA ligase (ADP-forming) activity
FVA81_13615	COG0039	L-malate dehydrogenase activity
FVA81_13620	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FVA81_13625	COG2845	Protein of unknown function (DUF459)
FVA81_13670	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FVA81_13675	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FVA81_13680	COG0181	hydroxymethylbilane synthase activity
FVA81_13720	COG1872	DUF167
FVA81_13725	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FVA81_13740	COG0339	signal peptide processing
FVA81_13750	COG2814	Major facilitator Superfamily
FVA81_13755	COG0137	argininosuccinate synthase activity
FVA81_13765	COG3609	addiction module antidote protein, CC2985 family
FVA81_13770	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_13775	COG1280	lysine exporter protein (LysE YggA)
FVA81_13780	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FVA81_13795	COG2154	pterin-4-alpha-carbinolamine dehydratase
FVA81_13800	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FVA81_13805	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FVA81_13815	COG4181	ATPase activity
FVA81_13825	COG0670	Belongs to the BI1 family
FVA81_13830	COG1329	Transcriptional regulator
FVA81_13840	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FVA81_13870	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_13880	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
FVA81_13890	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FVA81_13900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FVA81_13905	COG0142	geranyltranstransferase activity
FVA81_13910	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FVA81_13920	COG2885	chlorophyll binding
FVA81_13925	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FVA81_13930	COG2223	nitrite transmembrane transporter activity
FVA81_13935	COG0697	spore germination
FVA81_13940	COG1473	amidohydrolase
FVA81_13945	COG1309	transcriptional regulator
FVA81_13950	COG3459	Glycosyltransferase 36 associated
FVA81_13955	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FVA81_13970	COG3046	protein related to deoxyribodipyrimidine photolyase
FVA81_13985	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_14005	COG0395	ABC-type sugar transport system, permease component
FVA81_14010	COG1175	transmembrane transport
FVA81_14025	COG0246	Mannitol dehydrogenase
FVA81_14030	COG1802	Transcriptional regulator
FVA81_14035	COG2721	sulfolactate sulfo-lyase activity
FVA81_14055	COG1129	ABC transporter
FVA81_14060	COG1172	Belongs to the binding-protein-dependent transport system permease family
FVA81_14065	COG1063	alcohol dehydrogenase
FVA81_14070	COG0400	carboxylic ester hydrolase activity
FVA81_14075	COG0346	lactoylglutathione lyase activity
FVA81_14080	COG0583	DNA-binding transcription factor activity
FVA81_14085	COG0519	Catalyzes the synthesis of GMP from XMP
FVA81_14085	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FVA81_14090	COG1802	Transcriptional regulator
FVA81_14105	COG2188	Transcriptional regulator
FVA81_14110	COG3624	Phosphonate C-P lyase system protein PhnG
FVA81_14115	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FVA81_14120	COG3626	phosphonate metabolism
FVA81_14125	COG3627	carbon phosphorus lyase activity
FVA81_14130	COG4107	phosphonate C-P lyase system protein PhnK
FVA81_14135	COG4778	phosphonate C-P lyase system protein PhnL
FVA81_14145	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FVA81_14155	COG3639	organic phosphonate transmembrane transporter activity
FVA81_14160	COG3639	organic phosphonate transmembrane transporter activity
FVA81_14165	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FVA81_14170	COG3454	Phosphonate metabolism
FVA81_14175	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FVA81_14180	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FVA81_14185	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FVA81_14190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FVA81_14205	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FVA81_14210	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FVA81_14215	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FVA81_14220	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FVA81_14225	COG0799	negative regulation of ribosome biogenesis
FVA81_14230	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FVA81_14240	COG0793	Belongs to the peptidase S41A family
FVA81_14250	COG0494	nUDIX hydrolase
FVA81_14270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FVA81_14275	COG0587	DNA-directed DNA polymerase activity
FVA81_14320	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FVA81_14325	COG4783	chaperone-mediated protein folding
FVA81_14330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FVA81_14335	COG0473	3-isopropylmalate dehydrogenase activity
FVA81_14340	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FVA81_14345	COG0066	3-isopropylmalate dehydratase activity
FVA81_14365	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FVA81_14390	COG3118	belongs to the thioredoxin family
FVA81_14400	COG2835	tetraacyldisaccharide 4'-kinase activity
FVA81_14405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FVA81_14410	COG1946	Acyl-CoA thioesterase
FVA81_14415	COG0347	Belongs to the P(II) protein family
FVA81_14420	COG0004	ammonium transporteR
FVA81_14425	COG1674	ftsk spoiiie
FVA81_14430	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FVA81_14445	COG0745	RESPONSE REGULATOR receiver
FVA81_14460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FVA81_14465	COG0765	amino acid transport
FVA81_14475	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FVA81_14485	COG0335	large ribosomal subunit rRNA binding
FVA81_14495	COG0336	Belongs to the RNA methyltransferase TrmD family
FVA81_14500	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FVA81_14505	COG0228	four-way junction DNA binding
FVA81_14510	COG1605	Chorismate mutase
FVA81_14510	COG0287	Prephenate dehydrogenase
FVA81_14515	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FVA81_14525	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FVA81_14540	COG2022	thiamine diphosphate biosynthetic process
FVA81_14550	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FVA81_14555	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FVA81_14560	COG0552	protein localization to endoplasmic reticulum
FVA81_14565	COG2917	probably involved in intracellular septation
FVA81_14585	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FVA81_14590	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FVA81_14595	COG4133	protoheme IX ABC transporter activity
FVA81_14600	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FVA81_14610	COG0800	Aldolase
FVA81_14615	COG3734	2-keto-3-deoxy-galactonokinase
FVA81_14640	COG4214	carbohydrate transport
FVA81_14670	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FVA81_14680	COG0288	reversible hydration of carbon dioxide
FVA81_14695	COG2270	Major facilitator Superfamily
FVA81_14700	COG0138	bifunctional purine biosynthesis protein purh
FVA81_14710	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FVA81_14715	COG0501	Belongs to the peptidase M48B family
FVA81_14730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FVA81_14745	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FVA81_14750	COG0495	leucyl-tRNA aminoacylation
FVA81_14765	COG1475	DNA binding
FVA81_14770	COG1192	Involved in chromosome partitioning
FVA81_14775	COG0357	Ribosomal RNA small subunit methyltransferase G
FVA81_14780	COG0445	tRNA wobble uridine modification
FVA81_14785	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FVA81_14790	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FVA81_14800	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FVA81_14805	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FVA81_14810	COG0424	maF-like protein
FVA81_14815	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FVA81_14820	COG0237	dephospho-CoA kinase activity
FVA81_14825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FVA81_14830	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FVA81_14860	COG0187	DNA topoisomerase II activity
FVA81_14885	COG0135	phosphoribosylanthranilate isomerase activity
FVA81_14890	COG0133	tryptophan synthase activity
FVA81_14895	COG0159	tryptophan synthase activity
FVA81_14900	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FVA81_14915	COG1074	ATP-dependent DNA helicase activity
FVA81_14925	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FVA81_14930	COG3178	'Phosphotransferase
FVA81_14935	COG2205	protein histidine kinase activity
FVA81_14940	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FVA81_14945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FVA81_14950	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FVA81_14950	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FVA81_14955	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FVA81_14960	COG0642	Histidine kinase
FVA81_14965	COG0745	RESPONSE REGULATOR receiver
FVA81_14970	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FVA81_14980	COG3145	DNA-N1-methyladenine dioxygenase activity
FVA81_14985	COG1072	(Pantothenic acid kinase))
FVA81_14990	COG0140	phosphoribosyl-ATP diphosphatase activity
FVA81_14995	COG0107	imidazoleglycerol-phosphate synthase activity
FVA81_15000	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FVA81_15005	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FVA81_15010	COG0131	Imidazoleglycerol-phosphate dehydratase
FVA81_15015	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FVA81_15020	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FVA81_15040	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FVA81_15045	COG1376	ErfK ybiS ycfS ynhG family protein
FVA81_15055	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FVA81_15065	COG1643	Atp-dependent helicase
FVA81_15070	COG2423	ornithine cyclodeaminase activity
FVA81_15105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FVA81_15110	COG0154	amidase activity
FVA81_15120	COG1172	Belongs to the binding-protein-dependent transport system permease family
FVA81_15125	COG1129	ABC transporter
FVA81_15140	COG1609	Transcriptional regulator
FVA81_15145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FVA81_15150	COG0154	amidase activity
FVA81_15155	COG0154	amidase activity
FVA81_15165	COG1335	isochorismatase
FVA81_15170	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FVA81_15175	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_15180	COG1129	ABC transporter
FVA81_15185	COG1879	ABC-type sugar transport system periplasmic component
FVA81_15190	COG1172	Belongs to the binding-protein-dependent transport system permease family
FVA81_15195	COG3959	Transketolase, thiamine diphosphate binding domain
FVA81_15200	COG3958	Transketolase
FVA81_15205	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FVA81_15210	COG2390	Transcriptional regulator
FVA81_15215	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_15230	COG0395	ABC-type sugar transport system, permease component
FVA81_15240	COG3842	ATPase activity
FVA81_15245	COG3534	alpha-L-arabinofuranosidase
FVA81_15255	COG1648	precorrin-2 dehydrogenase activity
FVA81_15255	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FVA81_15260	COG0243	molybdopterin cofactor binding
FVA81_15270	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FVA81_15275	COG1116	anion transmembrane transporter activity
FVA81_15285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FVA81_15290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FVA81_15295	COG3707	response regulator
FVA81_15300	COG0477	Major facilitator Superfamily
FVA81_15305	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FVA81_15310	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FVA81_15315	COG1845	cytochrome c oxidase, subunit III
FVA81_15320	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FVA81_15350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FVA81_15365	COG1335	isochorismatase
FVA81_15385	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FVA81_15395	COG2986	histidine ammonia-lyase
FVA81_15400	COG1228	amidohydrolase
FVA81_15410	COG0402	S-adenosylhomocysteine deaminase activity
FVA81_15440	COG0395	ABC-type sugar transport system, permease component
FVA81_15465	COG1252	NADH dehydrogenase
FVA81_15470	COG1120	ATPase activity
FVA81_15480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FVA81_15495	COG3842	ATPase activity
FVA81_15500	COG3842	ATPase activity
FVA81_15510	COG0395	ABC-type sugar transport system, permease component
FVA81_15530	COG1793	dna ligase
FVA81_15545	COG3806	Anti-sigma factor
FVA81_15550	COG1595	DNA-templated transcription, initiation
FVA81_15565	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FVA81_15570	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_15575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FVA81_15580	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FVA81_15600	COG0539	negative regulation of cytoplasmic translation
FVA81_15605	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FVA81_15645	COG2860	membrane
FVA81_15655	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FVA81_15680	COG1185	polyribonucleotide nucleotidyltransferase activity
FVA81_15685	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FVA81_15690	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FVA81_15695	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FVA81_15700	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FVA81_15700	COG3064	Membrane
FVA81_15710	COG0195	Participates in both transcription termination and antitermination
FVA81_15710	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FVA81_15715	COG0779	Required for maturation of 30S ribosomal subunits
FVA81_15720	COG2814	Major facilitator Superfamily
FVA81_15730	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FVA81_15735	COG2258	MOSC domain
FVA81_15745	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FVA81_15750	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FVA81_15765	COG2816	NAD+ diphosphatase activity
FVA81_15770	COG0077	Prephenate dehydratase
FVA81_15770	COG1605	Chorismate mutase
FVA81_15775	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FVA81_15780	COG3474	cytochrome
FVA81_15790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FVA81_15815	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FVA81_15825	COG2900	Belongs to the SlyX family
FVA81_15840	COG0484	heat shock protein binding
FVA81_15850	COG0443	Heat shock 70 kDa protein
FVA81_15855	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FVA81_15860	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FVA81_15875	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FVA81_15875	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FVA81_15885	COG0588	phosphoglycerate mutase activity
FVA81_15890	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FVA81_15895	COG1132	(ABC) transporter
FVA81_15900	COG0837	glucose binding
FVA81_15905	COG1803	Methylglyoxal synthase
FVA81_15910	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FVA81_15915	COG4166	transmembrane transport
FVA81_15920	COG4174	ABC transporter (Permease)
FVA81_15925	COG4239	(ABC) transporter, permease
FVA81_15940	COG4172	Belongs to the ABC transporter superfamily
FVA81_15955	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FVA81_15990	COG4964	Belongs to the GSP D family
FVA81_16025	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FVA81_16030	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FVA81_16035	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FVA81_16045	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FVA81_16050	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FVA81_16055	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FVA81_16085	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FVA81_16110	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FVA81_16115	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FVA81_16140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FVA81_16150	COG1126	abc transporter atp-binding protein
FVA81_16175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FVA81_16185	COG0367	asparagine synthase
FVA81_16190	COG2918	glutathione biosynthetic process
FVA81_16190	COG0189	ligase activity
FVA81_16225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FVA81_16235	COG0791	NLP P60 protein
FVA81_16275	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FVA81_16290	COG3422	double-strand break repair
FVA81_16320	COG0481	GTPase activity
FVA81_16325	COG3795	YCII-related domain
FVA81_16330	COG4941	Belongs to the sigma-70 factor family
FVA81_16335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FVA81_16380	COG4529	Protein conserved in bacteria
FVA81_16390	COG1063	alcohol dehydrogenase
FVA81_16430	COG1733	regulation of RNA biosynthetic process
FVA81_16440	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FVA81_16455	COG2271	Major facilitator Superfamily
FVA81_16465	COG0596	Alpha beta hydrolase
FVA81_16470	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FVA81_16485	COG0745	RESPONSE REGULATOR receiver
FVA81_16490	COG0642	Histidine kinase
FVA81_16495	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FVA81_16500	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FVA81_16510	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FVA81_16520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FVA81_16520	COG0072	phenylalanine-tRNA ligase activity
FVA81_16525	COG1162	GTPase activity
FVA81_16530	COG1120	ATPase activity
FVA81_16535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FVA81_16545	COG1725	Transcriptional regulator
FVA81_16550	COG0697	spore germination
FVA81_16555	COG0667	Aldo Keto reductase
FVA81_16560	COG0667	Aldo Keto reductase
FVA81_16585	COG1570	exodeoxyribonuclease VII activity
FVA81_16590	COG2249	NAD(P)H dehydrogenase (quinone) activity
FVA81_16595	COG1278	Cold shock
FVA81_16615	COG2309	aminopeptidase activity
FVA81_16625	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FVA81_16630	COG1393	Belongs to the ArsC family
FVA81_16645	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FVA81_16645	COG0519	Catalyzes the synthesis of GMP from XMP
FVA81_16660	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FVA81_16690	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FVA81_16700	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FVA81_16710	COG1968	undecaprenyl-diphosphatase activity
FVA81_16725	COG0284	orotidine-5'-phosphate decarboxylase activity
FVA81_16735	COG3963	phosphatidate phosphatase activity
FVA81_16740	COG0592	DNA-directed DNA polymerase activity
FVA81_16745	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FVA81_16750	COG0792	nuclease activity
FVA81_16760	COG1175	transmembrane transport
FVA81_16765	COG0395	ABC-type sugar transport system, permease component
FVA81_16770	COG3842	ATPase activity
FVA81_16780	COG0189	ligase activity
FVA81_16785	COG0606	chelatase, subunit chli
FVA81_16790	COG3920	Histidine kinase
FVA81_16800	COG1280	lysine exporter protein (LysE YggA)
FVA81_16805	COG1280	lysine exporter protein (LysE YggA)
FVA81_16820	COG1522	sequence-specific DNA binding
FVA81_16825	COG0756	dUTP diphosphatase activity
FVA81_16830	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FVA81_16840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FVA81_16850	COG1741	Belongs to the pirin family
FVA81_16870	COG2204	response regulator
FVA81_16875	COG3437	response regulator, receiver
FVA81_16880	COG5002	protein histidine kinase activity
FVA81_16880	COG2198	Histidine kinase
FVA81_16880	COG0784	Response regulator, receiver
FVA81_16885	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FVA81_16890	COG2226	methyltransferase
FVA81_16895	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FVA81_16900	COG1024	Enoyl-CoA hydratase
FVA81_16905	COG0268	Binds directly to 16S ribosomal RNA
FVA81_16910	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FVA81_16915	COG2226	methyltransferase
FVA81_16920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FVA81_16925	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FVA81_16935	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FVA81_16940	COG1420	regulation of RNA biosynthetic process
FVA81_16945	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FVA81_16950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FVA81_16955	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FVA81_16965	COG1137	ATPase activity
FVA81_16970	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FVA81_16980	COG0776	regulation of translation
FVA81_16990	COG0116	Belongs to the methyltransferase superfamily
FVA81_16990	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FVA81_16995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FVA81_17000	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FVA81_17020	COG0280	phosphate acetyltransferase
FVA81_17020	COG0281	malic enzyme
FVA81_17025	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FVA81_17030	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FVA81_17045	COG0346	lactoylglutathione lyase activity
FVA81_17050	COG0180	Tryptophanyl-tRNA synthetase
FVA81_17060	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FVA81_17065	COG1214	PFAM Peptidase M22, glycoprotease
FVA81_17070	COG0456	acetyltransferase
FVA81_17085	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FVA81_17090	COG1702	phosphate starvation-inducible protein PhoH
FVA81_17095	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FVA81_17100	COG1253	flavin adenine dinucleotide binding
FVA81_17105	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FVA81_17110	COG1396	sequence-specific DNA binding
FVA81_17115	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FVA81_17120	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FVA81_17140	COG0840	transmembrane signaling receptor activity
FVA81_17145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FVA81_17155	COG0840	transmembrane signaling receptor activity
FVA81_17160	COG0840	transmembrane signaling receptor activity
FVA81_17165	COG0242	peptide deformylase activity
FVA81_17170	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FVA81_17175	COG0101	tRNA pseudouridine synthase activity
FVA81_17185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FVA81_17195	COG2171	N-acyltransferase activity
FVA81_17220	COG0477	Major facilitator Superfamily
FVA81_17225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FVA81_17240	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FVA81_17245	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FVA81_17255	COG0706	membrane insertase activity
FVA81_17260	COG0594	ribonuclease P activity
FVA81_17265	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FVA81_17270	COG5002	protein histidine kinase activity
FVA81_17280	COG2226	methyltransferase
FVA81_17285	COG3938	Belongs to the proline racemase family
FVA81_17290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FVA81_17345	COG0418	dihydroorotase activity
FVA81_17360	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FVA81_17375	COG2336	PFAM SpoVT AbrB
FVA81_17400	COG0166	Belongs to the GPI family
FVA81_17405	COG0318	PFAM AMP-dependent synthetase and ligase
FVA81_17435	COG2326	polyphosphate kinase activity
FVA81_17440	COG5002	protein histidine kinase activity
FVA81_17460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FVA81_17465	COG0704	Plays a role in the regulation of phosphate uptake
FVA81_17470	COG0745	RESPONSE REGULATOR receiver
FVA81_17480	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FVA81_17485	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FVA81_17490	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FVA81_17500	COG2967	ApaG domain
FVA81_17510	COG0717	Belongs to the dCTP deaminase family
FVA81_17570	COG0167	dihydroorotate dehydrogenase activity
FVA81_17575	COG0534	Mate efflux family protein
FVA81_17600	COG1201	RNA secondary structure unwinding
FVA81_17610	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FVA81_17625	COG0730	response to heat
FVA81_17635	COG1960	acyl-CoA dehydrogenase activity
FVA81_17640	COG0183	Belongs to the thiolase family
FVA81_17650	COG1250	3-hydroxyacyl-CoA dehydrogenase
FVA81_17650	COG1024	Enoyl-CoA hydratase
FVA81_17655	COG0584	glycerophosphoryl diester phosphodiesterase
FVA81_17665	COG0784	Response regulator, receiver
FVA81_17665	COG2198	Histidine kinase
FVA81_17665	COG2205	protein histidine kinase activity
FVA81_17670	COG1970	mechanosensitive ion channel activity
FVA81_17675	COG0436	Aminotransferase
FVA81_17685	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FVA81_17715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FVA81_17725	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FVA81_17730	COG5328	Belongs to the UPF0262 family
FVA81_17735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FVA81_17740	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FVA81_17745	COG0424	maF-like protein
FVA81_17750	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FVA81_17760	COG0840	transmembrane signaling receptor activity
FVA81_17760	COG2972	Histidine kinase
FVA81_17765	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FVA81_17770	COG3920	Histidine kinase
FVA81_17775	COG0784	Response regulator, receiver
FVA81_17775	COG4191	Histidine kinase
FVA81_17785	COG1278	Cold shock
FVA81_17805	COG0833	amino acid
FVA81_17815	COG0406	alpha-ribazole phosphatase activity
FVA81_17820	COG3842	ATPase activity
FVA81_17825	COG1178	ABC-type Fe3 transport system permease component
FVA81_17835	COG1737	Transcriptional regulator
FVA81_17840	COG4717	serine-type aminopeptidase activity
FVA81_17845	COG0420	3'-5' exonuclease activity
FVA81_17880	COG0747	negative chemotaxis
FVA81_17885	COG0601	transmembrane transport
FVA81_17890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FVA81_17895	COG0444	Belongs to the ABC transporter superfamily
FVA81_17900	COG4608	Belongs to the ABC transporter superfamily
FVA81_17910	COG1522	sequence-specific DNA binding
FVA81_17915	COG1448	Aminotransferase
FVA81_17925	COG1120	ATPase activity
FVA81_17930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FVA81_17945	COG2226	methyltransferase
FVA81_17950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FVA81_17965	COG1733	regulation of RNA biosynthetic process
FVA81_17990	COG3665	Urea carboxylase-associated protein
FVA81_17995	COG3665	Urea carboxylase-associated protein
FVA81_18020	COG1172	Belongs to the binding-protein-dependent transport system permease family
FVA81_18025	COG1129	ABC transporter
FVA81_18030	COG1879	ABC-type sugar transport system periplasmic component
FVA81_18035	COG4585	Histidine kinase
FVA81_18045	COG2137	regulation of response to DNA damage stimulus
FVA81_18055	COG2423	ornithine cyclodeaminase activity
FVA81_18070	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FVA81_18075	COG3618	amidohydrolase
FVA81_18080	COG4948	Mandelate Racemase Muconate Lactonizing
FVA81_18085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FVA81_18090	COG2186	Transcriptional regulator
FVA81_18095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FVA81_18125	COG2274	protein secretion by the type I secretion system
FVA81_18155	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FVA81_18155	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FVA81_18165	COG0297	glycogen (starch) synthase activity
FVA81_18180	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FVA81_18215	COG1012	belongs to the aldehyde dehydrogenase family
FVA81_18230	COG1024	Enoyl-CoA hydratase
FVA81_18240	COG4770	biotin carboxylase activity
FVA81_18245	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FVA81_18250	COG4336	lyase activity
FVA81_18255	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FVA81_18260	COG1914	H( )-stimulated, divalent metal cation uptake system
FVA81_18265	COG1802	Transcriptional regulator
FVA81_18270	COG1607	acyl-coa hydrolase
FVA81_18290	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FVA81_18330	COG0297	glycogen (starch) synthase activity
FVA81_18340	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FVA81_18355	COG0840	transmembrane signaling receptor activity
FVA81_18370	COG0643	Histidine kinase
FVA81_18370	COG2198	Histidine kinase
FVA81_18375	COG0835	chemotaxis
FVA81_18380	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FVA81_18385	COG2201	protein-glutamate methylesterase activity
FVA81_18390	COG0745	RESPONSE REGULATOR receiver
FVA81_18395	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FVA81_18405	COG1766	The M ring may be actively involved in energy transduction
FVA81_18410	COG2771	luxR family
FVA81_18425	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FVA81_18430	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FVA81_18435	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FVA81_18440	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FVA81_18445	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FVA81_18450	COG4786	Flagellar basal body rod
FVA81_18455	COG1157	protein secretion by the type III secretion system
FVA81_18465	COG1815	bacterial-type flagellum-dependent cell motility
FVA81_18470	COG1558	bacterial-type flagellum-dependent cell motility
FVA81_18475	COG1677	Flagellar hook-basal body complex protein FliE
FVA81_18480	COG4786	Flagellar basal body rod
FVA81_18485	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FVA81_18490	COG1706	bacterial-type flagellum-dependent cell motility
FVA81_18500	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FVA81_18510	COG1338	Plays a role in the flagellum-specific transport system
FVA81_18515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FVA81_18530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FVA81_18535	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FVA81_18545	COG1360	Flagellar Motor Protein
FVA81_18570	COG1749	Flagellar hook protein flgE
FVA81_18575	COG1256	bacterial-type flagellum assembly
FVA81_18575	COG4786	Flagellar basal body rod
FVA81_18590	COG5443	negative regulation of bacterial-type flagellum assembly
FVA81_18595	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FVA81_18600	COG4794	Type iii secretion
FVA81_18605	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FVA81_18645	COG1609	Transcriptional regulator
FVA81_18650	COG1653	transport
FVA81_18655	COG1175	transmembrane transport
FVA81_18660	COG0395	ABC-type sugar transport system, permease component
FVA81_18665	COG0366	Alpha amylase catalytic
FVA81_18670	COG3842	ATPase activity
FVA81_18680	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_18700	COG1595	DNA-templated transcription, initiation
FVA81_18715	COG0129	dihydroxy-acid dehydratase activity
FVA81_18720	COG0363	glucosamine-6-phosphate deaminase activity
FVA81_18725	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FVA81_18730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FVA81_18740	COG2081	HI0933 family
FVA81_18745	COG0840	transmembrane signaling receptor activity
FVA81_18745	COG2972	Histidine kinase
FVA81_18765	COG2224	Isocitrate lyase
FVA81_18775	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FVA81_18780	COG3842	ATPase activity
FVA81_18785	COG1176	ABC-type spermidine putrescine transport system, permease component I
FVA81_18790	COG1177	transmembrane transport
FVA81_18805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FVA81_18810	COG1178	ABC-type Fe3 transport system permease component
FVA81_18825	COG0745	RESPONSE REGULATOR receiver
FVA81_18830	COG2205	protein histidine kinase activity
FVA81_18855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FVA81_18870	COG1959	2 iron, 2 sulfur cluster binding
FVA81_18890	COG4269	membrane
FVA81_18895	COG4783	chaperone-mediated protein folding
FVA81_18900	COG1840	ABC-type Fe3 transport system, periplasmic component
FVA81_18905	COG1959	2 iron, 2 sulfur cluster binding
FVA81_18915	COG3265	gluconokinase activity
FVA81_18920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FVA81_18925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FVA81_18930	COG0174	glutamine synthetase
FVA81_18935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FVA81_18940	COG2832	Protein of unknown function (DUF454)
FVA81_18945	COG5001	Diguanylate cyclase
FVA81_18960	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FVA81_18990	COG1129	ABC transporter
FVA81_18995	COG1172	Belongs to the binding-protein-dependent transport system permease family
FVA81_19000	COG2390	Transcriptional regulator
FVA81_19005	COG0667	Aldo Keto reductase
FVA81_19010	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FVA81_19015	COG1830	Aldolase
FVA81_19020	COG1070	Carbohydrate kinase
FVA81_19040	COG2205	protein histidine kinase activity
FVA81_19045	COG0745	RESPONSE REGULATOR receiver
FVA81_19065	COG2194	sulfuric ester hydrolase activity
FVA81_19075	COG2111	Na H antiporter
FVA81_19075	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FVA81_19080	COG1006	Multisubunit Na H antiporter MnhC subunit
FVA81_19085	COG0651	ATP synthesis coupled electron transport
FVA81_19090	COG1863	multisubunit Na H antiporter MnhE subunit
FVA81_19095	COG2212	antiporter activity
FVA81_19100	COG1320	monovalent cation:proton antiporter activity
FVA81_19115	COG4774	siderophore transport
FVA81_19120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FVA81_19135	COG1120	ATPase activity
FVA81_19175	COG0444	Belongs to the ABC transporter superfamily
FVA81_19180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FVA81_19185	COG0601	transmembrane transport
FVA81_19200	COG2204	response regulator
FVA81_19210	COG1320	monovalent cation:proton antiporter activity
FVA81_19245	COG0784	Response regulator, receiver
FVA81_19245	COG4191	Histidine kinase
FVA81_19250	COG1309	transcriptional regulator
FVA81_19255	COG4221	oxidoreductase activity
FVA81_19265	COG0604	alcohol dehydrogenase
FVA81_19290	COG2205	protein histidine kinase activity
FVA81_19310	COG1024	Enoyl-CoA hydratase
FVA81_19320	COG1653	transport
FVA81_19325	COG1175	transmembrane transport
FVA81_19330	COG0395	ABC-type sugar transport system, permease component
FVA81_19335	COG3842	ATPase activity
FVA81_19345	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_19405	COG0438	transferase activity, transferring glycosyl groups
FVA81_19420	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_19445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FVA81_19455	COG0028	Belongs to the TPP enzyme family
FVA81_19500	COG0668	transmembrane transport
FVA81_19515	COG1253	flavin adenine dinucleotide binding
FVA81_19530	COG3685	Protein conserved in bacteria
FVA81_19535	COG0753	catalase activity
FVA81_19540	COG0784	Response regulator, receiver
FVA81_19540	COG4191	Histidine kinase
FVA81_19595	COG0673	inositol 2-dehydrogenase activity
FVA81_19610	COG4211	Belongs to the binding-protein-dependent transport system permease family
FVA81_19615	COG1129	ABC transporter
FVA81_19630	COG1609	Transcriptional regulator
FVA81_19650	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FVA81_19655	COG0673	inositol 2-dehydrogenase activity
FVA81_19660	COG2828	Protein conserved in bacteria
FVA81_19690	COG1309	transcriptional regulator
FVA81_19705	COG0577	efflux transmembrane transporter activity
FVA81_19705	COG1136	(ABC) transporter
FVA81_19730	COG0517	IMP dehydrogenase activity
FVA81_19735	COG4974	Belongs to the 'phage' integrase family
FVA81_19740	COG0210	DNA helicase
FVA81_19760	COG0248	Ppx GppA phosphatase
FVA81_19765	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FVA81_19775	COG0477	Major facilitator Superfamily
FVA81_19805	COG0412	Dienelactone hydrolase
FVA81_19830	COG0583	DNA-binding transcription factor activity
FVA81_19840	COG0840	transmembrane signaling receptor activity
FVA81_19865	COG0306	phosphate transporter
FVA81_19875	COG0561	phosphatase activity
FVA81_19880	COG0438	transferase activity, transferring glycosyl groups
FVA81_19890	COG1139	Iron-sulfur cluster binding protein
FVA81_19895	COG0247	lactate metabolic process
FVA81_19900	COG2186	Transcriptional regulator
FVA81_19915	COG0583	DNA-binding transcription factor activity
FVA81_19920	COG0277	FAD linked oxidase domain protein
FVA81_19925	COG0277	FAD linked oxidase domain protein
FVA81_19935	COG0247	lactate metabolic process
FVA81_19945	COG1376	ErfK ybiS ycfS ynhG family protein
FVA81_19950	COG1376	ErfK ybiS ycfS ynhG family protein
FVA81_19955	COG2818	Glycosylase
FVA81_19990	COG0124	histidyl-tRNA synthetase
FVA81_20000	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FVA81_20005	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FVA81_20015	COG2259	Doxx family
FVA81_20030	COG0459	protein refolding
FVA81_20035	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FVA81_20055	COG0196	riboflavin kinase activity
FVA81_20065	COG3706	GGDEF domain
FVA81_20070	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FVA81_20080	COG0456	acetyltransferase
FVA81_20090	COG0590	tRNA wobble adenosine to inosine editing
FVA81_20095	COG1187	pseudouridine synthase activity
FVA81_20100	COG0742	ribosomal rna small subunit methyltransferase
FVA81_20105	COG1752	Esterase of the alpha-beta hydrolase superfamily
FVA81_20110	COG0475	glutathione-regulated potassium exporter activity
FVA81_20110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FVA81_20115	COG0312	modulator of DNA gyrase
FVA81_20130	COG1519	Transferase
FVA81_20140	COG1663	tetraacyldisaccharide 4'-kinase activity
FVA81_20150	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FVA81_20155	COG2205	protein histidine kinase activity
FVA81_20155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FVA81_20160	COG5001	Diguanylate cyclase
FVA81_20160	COG3300	MHYT domain
FVA81_20165	COG0583	DNA-binding transcription factor activity
FVA81_20170	COG5598	trimethylamine methyltransferase
FVA81_20175	COG0446	pyridine nucleotide-disulphide oxidoreductase
FVA81_20175	COG1902	pentaerythritol trinitrate reductase activity
FVA81_20185	COG3386	PFAM SMP-30 Gluconolaconase
FVA81_20190	COG2197	response regulator
FVA81_20195	COG0489	protein tyrosine kinase activity
FVA81_20200	COG0598	Magnesium transport protein CorA
FVA81_20205	COG3158	transport of potassium into the cell
FVA81_20220	COG0356	it plays a direct role in the translocation of protons across the membrane
FVA81_20225	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FVA81_20230	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FVA81_20235	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FVA81_20245	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FVA81_20260	COG0521	Mo-molybdopterin cofactor biosynthetic process
FVA81_20265	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FVA81_20270	COG4785	May be involved in cell division
FVA81_20275	COG0142	geranyltranstransferase activity
FVA81_20305	COG0752	glycyl-tRNA synthetase alpha subunit
FVA81_20310	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FVA81_20320	COG1704	LemA family
FVA81_20325	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FVA81_20335	COG2852	Protein conserved in bacteria
FVA81_20345	COG0751	glycine-tRNA ligase activity
FVA81_20360	COG1683	Conserved Protein
FVA81_20365	COG0840	transmembrane signaling receptor activity
FVA81_20375	COG0151	Belongs to the GarS family
FVA81_20380	COG2183	response to ionizing radiation
FVA81_20395	COG2514	catechol 2,3-dioxygenase activity
FVA81_20410	COG3909	cytochrome
FVA81_20415	COG2010	Cytochrome c
FVA81_20445	COG0789	Transcriptional regulator
FVA81_20465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FVA81_20470	COG3713	MltA-interacting MipA family protein
FVA81_20475	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FVA81_20490	COG0725	ABC transporter, periplasmic molybdate-binding protein
FVA81_20495	COG4149	molybdate abc transporter
FVA81_20500	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FVA81_20505	COG3585	molybdate ion transport
FVA81_20505	COG2005	Transcriptional regulator
FVA81_20510	COG0277	FAD linked oxidase domain protein
FVA81_20515	COG0009	L-threonylcarbamoyladenylate synthase
FVA81_20530	COG4638	Rieske (2fe-2S)
FVA81_20545	COG0850	regulation of cytokinetic process
FVA81_20550	COG2894	cell division
FVA81_20555	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FVA81_20565	COG1960	acyl-CoA dehydrogenase activity
FVA81_20590	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FVA81_20605	COG0123	including yeast histone deacetylase and acetoin utilization protein
FVA81_20610	COG1722	exodeoxyribonuclease VII activity
FVA81_20620	COG2040	homocysteine
FVA81_20635	COG4215	(ABC) transporter
FVA81_20650	COG1522	sequence-specific DNA binding
FVA81_20670	COG1741	Belongs to the pirin family
FVA81_20675	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FVA81_20705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FVA81_20720	COG1268	BioY protein
FVA81_20725	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FVA81_20730	COG1122	ATPase activity
FVA81_20735	COG3214	Protein conserved in bacteria
FVA81_20755	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FVA81_20755	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FVA81_20760	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FVA81_20775	COG0406	alpha-ribazole phosphatase activity
FVA81_20780	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FVA81_20785	COG0484	heat shock protein binding
FVA81_20795	COG0259	pyridoxamine-phosphate oxidase activity
FVA81_20815	COG1686	Belongs to the peptidase S11 family
FVA81_20830	COG0312	modulator of DNA gyrase
FVA81_20845	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FVA81_20850	COG0109	protoheme IX farnesyltransferase activity
FVA81_20860	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FVA81_20875	COG3346	SURF1 family
FVA81_20885	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FVA81_20900	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FVA81_20905	COG0328	RNA-DNA hybrid ribonuclease activity
FVA81_20915	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FVA81_20915	COG0678	peroxiredoxin activity
FVA81_20925	COG1678	Uncharacterized ACR, COG1678
FVA81_20950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FVA81_20955	COG0612	Peptidase, M16
FVA81_20980	COG1597	lipid kinase activity
FVA81_20985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FVA81_21020	COG1268	BioY protein
FVA81_21030	COG2202	Pas domain
FVA81_21030	COG3920	Histidine kinase
FVA81_21050	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FVA81_21055	COG2885	chlorophyll binding
FVA81_21065	COG1194	a g-specific adenine glycosylase
FVA81_21090	COG1196	nuclear chromosome segregation
FVA81_21110	COG0738	Major facilitator superfamily
FVA81_21120	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FVA81_21120	COG0574	Belongs to the PEP-utilizing enzyme family
FVA81_21125	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FVA81_21130	COG0471	metal ion transport
FVA81_21130	COG3273	potassium ion transport
FVA81_21145	COG0300	oxidoreductase activity
FVA81_21160	COG0300	oxidoreductase activity
FVA81_21190	COG0693	protein deglycase activity
FVA81_21200	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FVA81_21205	COG1132	(ABC) transporter
FVA81_21220	COG3706	GGDEF domain
FVA81_21240	COG1609	Transcriptional regulator
FVA81_21255	COG2895	sulfate adenylyltransferase (ATP) activity
FVA81_21260	COG0175	sulfate reduction
FVA81_21265	COG0175	sulfate reduction
FVA81_21270	COG1959	2 iron, 2 sulfur cluster binding
FVA81_21300	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FVA81_21305	COG0659	secondary active sulfate transmembrane transporter activity
FVA81_21335	COG1253	flavin adenine dinucleotide binding
FVA81_21345	COG1609	Transcriptional regulator
FVA81_21380	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FVA81_21385	COG1012	belongs to the aldehyde dehydrogenase family
FVA81_21390	COG1309	transcriptional regulator
FVA81_21395	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FVA81_21400	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FVA81_21415	COG3300	MHYT domain
FVA81_21415	COG5001	Diguanylate cyclase
FVA81_21455	COG1349	DNA-binding transcription factor activity
FVA81_21465	COG0625	glutathione transferase activity
FVA81_21495	COG0477	Major facilitator Superfamily
FVA81_21500	COG0840	transmembrane signaling receptor activity
FVA81_21505	COG1376	ErfK ybiS ycfS ynhG family protein
FVA81_21510	COG1376	ErfK ybiS ycfS ynhG family protein
FVA81_21530	COG1846	Transcriptional regulator
FVA81_21535	COG1764	response to oxidative stress
FVA81_21545	COG1846	Transcriptional regulator
FVA81_21570	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FVA81_21575	COG1278	Cold shock
FVA81_21585	COG3239	Fatty acid desaturase
FVA81_21615	COG1742	UPF0060 membrane protein
FVA81_21635	COG0433	COG0433 Predicted ATPase
FVA81_21665	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_21675	COG2323	membrane
FVA81_21690	COG1238	metal cluster binding
FVA81_21715	COG1879	ABC-type sugar transport system periplasmic component
FVA81_21720	COG4214	carbohydrate transport
FVA81_21725	COG1129	ABC transporter
FVA81_21745	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FVA81_21750	COG1272	protein, Hemolysin III
FVA81_21765	COG1280	lysine exporter protein (LysE YggA)
FVA81_21775	COG2130	NADP-dependent
FVA81_21820	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FVA81_21830	COG2111	Na H antiporter
FVA81_21835	COG1006	Multisubunit Na H antiporter MnhC subunit
FVA81_21845	COG1863	multisubunit Na H antiporter MnhE subunit
FVA81_21850	COG2212	antiporter activity
FVA81_21855	COG1320	monovalent cation:proton antiporter activity
FVA81_21860	COG4957	zinc ion binding
FVA81_21885	COG2166	iron-sulfur cluster assembly
FVA81_21900	COG2205	protein histidine kinase activity
FVA81_21910	COG0840	transmembrane signaling receptor activity
FVA81_22000	COG2264	protein methyltransferase activity
FVA81_22030	COG3706	GGDEF domain
FVA81_22035	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FVA81_22040	COG2983	Belongs to the UPF0260 family
FVA81_22065	COG0789	Transcriptional regulator
FVA81_22075	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FVA81_22080	COG3706	GGDEF domain
FVA81_22120	COG4695	Portal protein
FVA81_22200	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
FVA81_22265	COG0745	RESPONSE REGULATOR receiver
FVA81_22270	COG2205	protein histidine kinase activity
FVA81_22280	COG4235	cytochrome complex assembly
FVA81_22285	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FVA81_22290	COG1138	Cytochrome C-type biogenesis protein
FVA81_22295	COG3088	subunit of a heme lyase
FVA81_22305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FVA81_22310	COG0745	RESPONSE REGULATOR receiver
FVA81_22320	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FVA81_22330	COG2202	Pas domain
FVA81_22330	COG2205	protein histidine kinase activity
FVA81_22335	COG0308	aminopeptidase N
FVA81_22340	COG0840	transmembrane signaling receptor activity
FVA81_22370	COG0443	Heat shock 70 kDa protein
FVA81_22385	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_22395	COG2084	Dehydrogenase
FVA81_22405	COG1376	ErfK ybiS ycfS ynhG family protein
FVA81_22410	COG1733	regulation of RNA biosynthetic process
FVA81_22420	COG1733	regulation of RNA biosynthetic process
FVA81_22425	COG2814	Major facilitator Superfamily
FVA81_22435	COG4172	Belongs to the ABC transporter superfamily
FVA81_22440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FVA81_22445	COG0601	transmembrane transport
FVA81_22455	COG0174	glutamine synthetase
FVA81_22470	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_22495	COG0667	Aldo Keto reductase
FVA81_22500	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FVA81_22520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FVA81_22545	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FVA81_22555	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FVA81_22565	COG0741	lytic transglycosylase activity
FVA81_22570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FVA81_22585	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FVA81_22595	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FVA81_22595	COG2169	Transcriptional regulator
FVA81_22605	COG1758	RNA polymerase activity
FVA81_22625	COG0736	holo-[acyl-carrier-protein] synthase activity
FVA81_22630	COG0681	Belongs to the peptidase S26 family
FVA81_22635	COG0571	ribonuclease III activity
FVA81_22640	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FVA81_22645	COG3180	Ammonia monooxygenase
FVA81_22655	COG1381	Involved in DNA repair and RecF pathway recombination
FVA81_22670	COG3217	Mosc domain protein beta barrel domain protein
FVA81_22670	COG0633	Ferredoxin
FVA81_22675	COG1418	mRNA catabolic process
FVA81_22685	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FVA81_22690	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FVA81_22705	COG0668	transmembrane transport
FVA81_22720	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FVA81_22745	COG0494	nUDIX hydrolase
FVA81_22755	COG1183	phosphatidylcholine synthase activity
FVA81_22760	COG0688	phosphatidylethanolamine metabolic process
FVA81_22765	COG3706	GGDEF domain
FVA81_22770	COG5265	(ABC) transporter
FVA81_22790	COG0583	DNA-binding transcription factor activity
FVA81_22795	COG2814	Major facilitator Superfamily
FVA81_22800	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FVA81_22820	COG0215	cysteine-tRNA ligase activity
FVA81_22825	COG3706	GGDEF domain
FVA81_22830	COG0697	spore germination
FVA81_22835	COG4221	oxidoreductase activity
FVA81_22840	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FVA81_22845	COG1286	toxin biosynthetic process
FVA81_22865	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FVA81_22890	COG0359	binds to the 23S rRNA
FVA81_22900	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FVA81_22905	COG0360	Binds together with S18 to 16S ribosomal RNA
FVA81_22920	COG0667	Aldo Keto reductase
FVA81_22925	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FVA81_22935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FVA81_22940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FVA81_22945	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FVA81_22950	COG1561	YicC-like family, N-terminal region
FVA81_22955	COG0194	GDP metabolic process
FVA81_22960	COG3119	arylsulfatase activity
FVA81_22975	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FVA81_22980	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FVA81_22990	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FVA81_23005	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FVA81_23030	COG0488	(ABC) transporter
FVA81_23050	COG0105	UTP biosynthetic process
FVA81_23070	COG0314	molybdopterin synthase activity
FVA81_23080	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FVA81_23085	COG0322	excinuclease ABC activity
FVA81_23090	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_23105	COG3719	Belongs to the RNase T2 family
FVA81_23110	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FVA81_23120	COG0494	nUDIX hydrolase
FVA81_23125	COG1132	(ABC) transporter
FVA81_23135	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FVA81_23140	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FVA81_23145	COG0628	permease
FVA81_23155	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FVA81_23160	COG0248	Ppx GppA phosphatase
FVA81_23190	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FVA81_23230	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FVA81_23240	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FVA81_23245	COG5001	Diguanylate cyclase
FVA81_23245	COG3300	MHYT domain
FVA81_23255	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FVA81_23265	COG0113	porphobilinogen synthase activity
FVA81_23285	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FVA81_23290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FVA81_23295	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FVA81_23295	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FVA81_23305	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FVA81_23310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FVA81_23315	COG2814	Major facilitator Superfamily
FVA81_23320	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FVA81_23340	COG0416	fatty acid biosynthetic process
FVA81_23345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FVA81_23350	COG0776	regulation of translation
FVA81_23390	COG0297	glycogen (starch) synthase activity
FVA81_23415	COG1612	heme a metabolic process
FVA81_23420	COG3384	dioxygenase
FVA81_23425	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FVA81_23430	COG0010	Belongs to the arginase family
FVA81_23435	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FVA81_23440	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FVA81_23450	COG1832	CoA-binding protein
FVA81_23460	COG1832	CoA-binding protein
FVA81_23490	COG2378	regulation of single-species biofilm formation
FVA81_23505	COG0740	serine-type endopeptidase activity
FVA81_23510	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FVA81_23515	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FVA81_23525	COG0697	spore germination
FVA81_23540	COG0667	Aldo Keto reductase
FVA81_23555	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FVA81_23560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FVA81_23570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FVA81_23595	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FVA81_23600	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FVA81_23605	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FVA81_23610	COG0649	NAD binding
FVA81_23620	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FVA81_23625	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FVA81_23640	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FVA81_23645	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FVA81_23655	COG0713	ATP synthesis coupled electron transport
FVA81_23670	COG1007	ATP synthesis coupled electron transport
FVA81_23695	COG0442	prolyl-tRNA aminoacylation
FVA81_23705	COG1136	(ABC) transporter
FVA81_23710	COG0587	DNA-directed DNA polymerase activity
FVA81_23725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FVA81_23740	COG0784	Response regulator, receiver
FVA81_23745	COG3706	GGDEF domain
FVA81_23745	COG0745	RESPONSE REGULATOR receiver
FVA81_23750	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FVA81_23755	COG0477	Major facilitator Superfamily
FVA81_23765	COG0557	exoribonuclease II activity
FVA81_23770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FVA81_23770	COG1754	DNA topoisomerase type I activity
FVA81_23780	COG0758	DNA mediated transformation
FVA81_23785	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FVA81_23790	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FVA81_23795	COG0540	Belongs to the ATCase OTCase family
FVA81_23800	COG1960	acyl-CoA dehydrogenase activity
FVA81_23820	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FVA81_23825	COG2824	Alkylphosphonate utilization operon protein PhnA
FVA81_23830	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FVA81_23835	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FVA81_23840	COG0154	amidase activity
FVA81_23860	COG3811	Belongs to the UPF0386 family
FVA81_23865	COG0456	acetyltransferase
FVA81_23875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FVA81_23920	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FVA81_23930	COG0511	ligase activity, forming carbon-carbon bonds
FVA81_23935	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FVA81_23945	COG0436	Aminotransferase
FVA81_23955	COG1530	ribonuclease E activity
FVA81_23960	COG1388	LysM domain
FVA81_23960	COG0860	N-Acetylmuramoyl-L-alanine amidase
FVA81_23980	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FVA81_24090	COG0582	viral genome integration into host DNA
FVA81_24105	COG1215	transferase activity, transferring glycosyl groups
FVA81_24110	COG3769	mannosylglycerate metabolic process
FVA81_24130	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FVA81_24160	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FVA81_24165	COG0081	regulation of translation
FVA81_24170	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FVA81_24175	COG0222	ribosome binding
FVA81_24180	COG0085	RNA polymerase activity
FVA81_24185	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FVA81_24195	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FVA81_24200	COG0049	tRNA binding
FVA81_24205	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FVA81_24210	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FVA81_24215	COG0051	transcription antitermination factor activity, RNA binding
FVA81_24220	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FVA81_24225	COG0088	Forms part of the polypeptide exit tunnel
FVA81_24230	COG0089	rRNA binding
FVA81_24235	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FVA81_24240	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FVA81_24245	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FVA81_24250	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FVA81_24255	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FVA81_24260	COG0255	Belongs to the universal ribosomal protein uL29 family
FVA81_24265	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FVA81_24270	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FVA81_24275	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FVA81_24280	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FVA81_24285	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FVA81_24290	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FVA81_24295	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FVA81_24300	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FVA81_24305	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FVA81_24310	COG1841	ribosomal large subunit assembly
FVA81_24315	COG0200	Binds to the 23S rRNA
FVA81_24325	COG0563	adenylate kinase activity
FVA81_24330	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FVA81_24335	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FVA81_24340	COG0202	RNA polymerase activity
FVA81_24345	COG0203	ribosomal protein L17
FVA81_24350	COG4941	Belongs to the sigma-70 factor family
FVA81_24360	COG3795	YCII-related domain
FVA81_24365	COG3739	integral membrane protein
FVA81_24375	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FVA81_24380	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FVA81_24390	COG0129	dihydroxy-acid dehydratase activity
FVA81_24405	COG0235	Class ii aldolase
FVA81_24445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FVA81_24450	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FVA81_24470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FVA81_24475	COG0840	transmembrane signaling receptor activity
FVA81_24480	COG0702	epimerase
FVA81_24510	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FVA81_24520	COG1058	Belongs to the CinA family
FVA81_24520	COG1546	Belongs to the CinA family
FVA81_24525	COG0655	NAD(P)H dehydrogenase (quinone) activity
FVA81_24560	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FVA81_24600	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FVA81_24635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FVA81_24645	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FVA81_24650	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FVA81_24665	COG3300	MHYT domain
FVA81_24665	COG5001	Diguanylate cyclase
FVA81_24670	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FVA81_24675	COG0583	DNA-binding transcription factor activity
FVA81_24680	COG0737	Belongs to the 5'-nucleotidase family
FVA81_24700	COG1522	sequence-specific DNA binding
FVA81_24705	COG0686	Belongs to the AlaDH PNT family
FVA81_24730	COG2897	thiosulfate sulfurtransferase activity
FVA81_24740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FVA81_24745	COG4115	mRNA cleavage
FVA81_24750	COG2161	toxin-antitoxin pair type II binding
FVA81_24755	COG0415	Belongs to the DNA photolyase family
FVA81_24785	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FVA81_24795	COG0525	valine-tRNA ligase activity
FVA81_24805	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FVA81_24815	COG0316	Belongs to the HesB IscA family
FVA81_24820	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FVA81_24825	COG0018	arginyl-trna synthetase
FVA81_24835	COG1472	Belongs to the glycosyl hydrolase 3 family
FVA81_24845	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FVA81_24855	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FVA81_24860	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FVA81_24865	COG0805	protein transport
FVA81_24870	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FVA81_24875	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FVA81_24880	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FVA81_24920	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FVA81_24930	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FVA81_24935	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FVA81_24955	COG2945	thiolester hydrolase activity
FVA81_24960	COG1104	cysteine desulfurase activity
FVA81_24965	COG0719	Fe-S assembly protein
FVA81_24970	COG0396	ATPase activity
FVA81_24975	COG0719	Fe-S assembly protein
FVA81_24980	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FVA81_24985	COG2151	metal-sulfur cluster biosynthetic enzyme
FVA81_24990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FVA81_24995	COG2267	carboxylic ester hydrolase activity
FVA81_25000	COG0251	oxidation-reduction process
FVA81_25005	COG1335	isochorismatase
FVA81_25010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FVA81_25015	COG0316	Belongs to the HesB IscA family
FVA81_25035	COG3916	Acyl-homoserine-lactone synthase
FVA81_25055	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FVA81_25055	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FVA81_25060	COG0509	glycine decarboxylation via glycine cleavage system
FVA81_25065	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FVA81_25090	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FVA81_25100	COG0546	phosphoglycolate phosphatase activity
FVA81_25175	COG2875	Belongs to the precorrin methyltransferase family
FVA81_25185	COG1957	nucleoside hydrolase
FVA81_25210	COG0544	peptidyl-prolyl cis-trans isomerase activity
FVA81_25215	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FVA81_25225	COG3237	CsbD-like
FVA81_25250	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FVA81_25250	COG2755	lipolytic protein G-D-S-L family
FVA81_25260	COG0024	Methionine aminopeptidase
FVA81_25265	COG1489	DNA binding
FVA81_25270	COG1733	regulation of RNA biosynthetic process
FVA81_25280	COG1028	Short-chain dehydrogenase reductase Sdr
FVA81_25285	COG3243	poly(R)-hydroxyalkanoic acid synthase
FVA81_25295	COG0436	Aminotransferase
FVA81_25310	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FVA81_25335	COG0346	lactoylglutathione lyase activity
FVA81_25340	COG1278	Cold shock
FVA81_25370	COG1126	abc transporter atp-binding protein
FVA81_25375	COG0765	amino acid transport
FVA81_25380	COG4597	amino acid ABC transporter
FVA81_25385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FVA81_25390	COG0626	cystathionine gamma-synthase activity
FVA81_25430	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FVA81_25455	COG0537	adenosine 5'-monophosphoramidase activity
FVA81_25480	COG0052	Belongs to the universal ribosomal protein uS2 family
FVA81_25485	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FVA81_25490	COG0528	UMP kinase activity
FVA81_25495	COG0233	cytoplasmic translational termination
FVA81_25500	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FVA81_25510	COG0750	zinc metalloprotease
FVA81_25515	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FVA81_25520	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FVA81_25525	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FVA81_25530	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FVA81_25535	COG3494	Protein of unknown function (DUF1009)