locus-tag	class	description
HTY51_00005	ENOG4105CN7	Flagellar biosynthetic protein FliP
HTY51_00010	ENOG4105VS8	Flagellar biosynthetic protein fliq
HTY51_00040	ENOG4105CBS	Chea signal transduction histidine kinase
HTY51_00045	ENOG4108V3W	Chemotaxis protein, CheW
HTY51_00050	ENOG4105BZU	Histidine kinase
HTY51_00055	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
HTY51_00060	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HTY51_00065	ENOG4105C5H	ABC transporter
HTY51_00125	ENOG4105CEY	Amp-dependent synthetase and ligase
HTY51_00135	ENOG4108JU5	Magnesium and cobalt efflux protein
HTY51_00140	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HTY51_00145	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
HTY51_00150	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HTY51_00155	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HTY51_00175	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HTY51_00190	ENOG4108Z6Z	Transcriptional regulator
HTY51_00195	ENOG4105C1G	acyl-Coa dehydrogenase
HTY51_00200	ENOG41077A9	carbonic anhydrase
HTY51_00205	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HTY51_00210	ENOG4105CHU	acetyl-coa acetyltransferase
HTY51_00215	ENOG4105C8Q	Methyl-accepting chemotaxis
HTY51_00220	ENOG4105C1G	acyl-Coa dehydrogenase
HTY51_00235	ENOG4105K5B	UPF0225 protein
HTY51_00240	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
HTY51_00245	ENOG4105BZU	Histidine kinase
HTY51_00250	ENOG4107QX3	carboxylase
HTY51_00260	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HTY51_00265	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HTY51_00275	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HTY51_00280	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HTY51_00295	ENOG4105CP9	extracellular ligand-binding receptor
HTY51_00300	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HTY51_00310	ENOG4105BZU	Histidine kinase
HTY51_00325	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HTY51_00330	ENOG4107QWG	2-Nitropropane dioxygenase
HTY51_00335	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HTY51_00340	ENOG4105DX0	Hemolysin A
HTY51_00345	ENOG4105SYT	Methylenetetrahydrofolate reductase
HTY51_00355	ENOG4105D6S	protein involved in catabolism of external DNA
HTY51_00360	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
HTY51_00365	ENOG4107QPV	Serine Threonine protein kinase
HTY51_00370	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HTY51_00375	ENOG4108UJD	30S ribosomal protein S9
HTY51_00390	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HTY51_00395	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HTY51_00400	ENOG4105DR5	peptidase
HTY51_00420	ENOG4105T95	Thiol disulfide interChange protein
HTY51_00425	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HTY51_00430	ENOG4105QVC	MOSC domain-containing protein
HTY51_00435	ENOG4105F04	LysR family Transcriptional regulator
HTY51_00440	ENOG4105C7F	AcnD-accessory protein PrpF
HTY51_00445	ENOG4105C3G	gtp-binding protein
HTY51_00475	ENOG4105W39	Membrane
HTY51_00480	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HTY51_00490	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HTY51_00495	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HTY51_00505	ENOG4105VCQ	rubredoxin
HTY51_00510	ENOG4108UNF	response regulator
HTY51_00515	ENOG4105M3Z	response regulator
HTY51_00520	ENOG4108V3W	Chemotaxis protein, CheW
HTY51_00525	ENOG4105C8Q	Methyl-accepting chemotaxis
HTY51_00540	ENOG4108UJU	UPF0301 protein
HTY51_00545	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HTY51_00550	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HTY51_00555	ENOG4105CXT	aspartate transcarbamylase
HTY51_00560	ENOG4105CD3	dihydroorotase
HTY51_00565	ENOG4108Z20	Acyl-transferase
HTY51_00570	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HTY51_00575	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
HTY51_00590	ENOG4107S7U	Sulfide dehydrogenase
HTY51_00600	ENOG4105CUC	YeeE YedE family protein
HTY51_00605	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
HTY51_00615	ENOG4105C8Q	Methyl-accepting chemotaxis
HTY51_00640	ENOG4105KHC	sulfurtransferase
HTY51_00645	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HTY51_00655	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HTY51_00660	ENOG4105C9A	Phoh family
HTY51_00665	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HTY51_00670	ENOG4108UHE	carbonic anhydrase
HTY51_00675	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HTY51_00700	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HTY51_00715	ENOG4105CVJ	phosphoglycerate mutase
HTY51_00725	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HTY51_00760	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HTY51_00775	ENOG4105E4C	Lytic transglycosylase catalytic
HTY51_00780	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HTY51_00800	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HTY51_00845	ENOG4105D06	uba thif-type nad fad binding protein
HTY51_00885	ENOG4105GR3	Histidine kinase
HTY51_00910	ENOG4108VVQ	metallophosphoesterase
HTY51_00920	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HTY51_00940	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HTY51_00995	ENOG4107Y80	Major Facilitator superfamily
HTY51_01010	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
HTY51_01015	ENOG4107ZT5	Thiol disulfide interchange protein
HTY51_01020	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HTY51_01025	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HTY51_01030	ENOG4105DHQ	Histidine kinase
HTY51_01055	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HTY51_01065	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HTY51_01075	ENOG4105DS1	cytochrome b561
HTY51_01085	ENOG4105E0F	Histidine kinase
HTY51_01110	ENOG4105EMN	RNA polymerase sigma factor
HTY51_01120	ENOG4107VGR	Catalase
HTY51_01130	ENOG4108VSE	mercuric transport protein
HTY51_01135	ENOG4105W1Y	Transcriptional regulator
HTY51_01170	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
HTY51_01175	ENOG4108XHQ	(2Fe-2S)-binding domain protein
HTY51_01200	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HTY51_01220	ENOG4105E7A	Glutamine amidotransferase
HTY51_01230	ENOG4105DUM	transcriptional regulator, lysR family
HTY51_01235	ENOG4105DUM	transcriptional regulator, lysR family
HTY51_01240	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
HTY51_01245	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
HTY51_01250	ENOG4106F1P	AAA ATPase, central domain protein
HTY51_01255	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
HTY51_01260	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HTY51_01265	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
HTY51_01270	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HTY51_01275	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HTY51_01280	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HTY51_01285	ENOG4105BZA	Phosphoglycerate kinase
HTY51_01290	ENOG4105D2N	Aldolase
HTY51_01300	ENOG4105VPX	protein, conserved in bacteria
HTY51_01325	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HTY51_01330	ENOG4105W2Z	cytochrome C, class I
HTY51_01370	ENOG4105C8Q	Methyl-accepting chemotaxis
HTY51_01400	ENOG4106RE7	Cytochrome
HTY51_01410	ENOG4107HP6	Transcriptional regulator
HTY51_01420	ENOG4107QNJ	CoA-transferase subunit B
HTY51_01425	ENOG4105CHU	acetyl-coa acetyltransferase
HTY51_01430	ENOG4105EN6	Membrane
HTY51_01440	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HTY51_01475	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HTY51_01480	ENOG4105K56	Transcriptional regulator
HTY51_01485	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HTY51_01545	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HTY51_01570	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
HTY51_01585	ENOG4108QMY	dioxygenase
HTY51_01610	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HTY51_01615	ENOG41081UC	Inherit from COG: Competence protein
HTY51_01620	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HTY51_01625	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
HTY51_01630	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HTY51_01635	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
HTY51_01645	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
HTY51_01665	ENOG4107VFP	cytochrome oxidase assembly
HTY51_01670	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HTY51_01685	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HTY51_01705	ENOG4105KT5	UmuD protein
HTY51_01710	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HTY51_01715	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HTY51_01720	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HTY51_01725	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HTY51_01745	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
HTY51_01750	ENOG4108IJ9	(ABC) transporter
HTY51_01760	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
HTY51_01780	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HTY51_01795	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HTY51_01815	ENOG4105C9M	aspartyl-trna synthetase
HTY51_01820	ENOG4108TIT	dATP pyrophosphohydrolase
HTY51_01830	ENOG4105DZQ	phospholipase D Transphosphatidylase
HTY51_01835	ENOG4105EUJ	GTP cyclohydrolase i
HTY51_01860	ENOG4105D06	uba thif-type nad fad binding protein
HTY51_01865	ENOG4105CN1	protease
HTY51_01870	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HTY51_01875	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HTY51_01880	ENOG4105VW4	glutaredoxin 3
HTY51_01885	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HTY51_01890	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HTY51_01900	ENOG4108DIG	cyanophycin synthetase
HTY51_01905	ENOG4105BZ1	(ABC) transporter
HTY51_01915	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HTY51_01920	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HTY51_01925	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HTY51_01935	ENOG4105CVJ	phosphoglycerate mutase
HTY51_01940	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HTY51_01950	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HTY51_01955	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HTY51_01960	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HTY51_01970	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HTY51_01985	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HTY51_01995	ENOG4105CEN	a g-specific adenine glycosylase
HTY51_02000	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HTY51_02005	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HTY51_02010	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HTY51_02015	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
HTY51_02030	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
HTY51_02045	ENOG4108RRZ	Transcription elongation factor GreB
HTY51_02050	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HTY51_02055	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HTY51_02060	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HTY51_02065	ENOG4105DSJ	YicC domain protein
HTY51_02085	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HTY51_02090	ENOG4105CSA	Coproporphyrinogen iii oxidase
HTY51_02100	ENOG4105BZU	Histidine kinase
HTY51_02165	ENOG4105KK4	UPF0060 membrane protein
HTY51_02170	ENOG4105W1Y	Transcriptional regulator
HTY51_02185	ENOG4105DZ2	Transcriptional regulator
HTY51_02200	ENOG4108NF7	phage-type endonuclease
HTY51_02255	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HTY51_02260	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
HTY51_02265	ENOG41060W2	glyoxylate carboligase
HTY51_02270	ENOG4105CC0	LysR family Transcriptional regulator
HTY51_02315	ENOG4105DHP	deoxycytidine triphosphate deaminase
HTY51_02325	ENOG4105F84	Ornithine cyclodeaminase
HTY51_02330	ENOG4105C1J	atp-dependent rna helicase
HTY51_02335	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HTY51_02340	ENOG4107TPY	serine threonine protein kinase
HTY51_02360	ENOG4107S90	membrAne
HTY51_02375	ENOG4108JU3	Alkyl hydroperoxide reductase
HTY51_02380	ENOG4108V0P	LemA family
HTY51_02400	ENOG4105D16	lipopolysaccharide heptosyltransferase i
HTY51_02405	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HTY51_02430	ENOG4105VFE	sira family
HTY51_02435	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HTY51_02450	ENOG4105YA8	Transcriptional regulator
HTY51_02455	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HTY51_02460	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HTY51_02480	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HTY51_02485	ENOG4108N2Y	auxin Efflux
HTY51_02490	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HTY51_02505	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
HTY51_02515	ENOG4105BZU	Histidine kinase
HTY51_02520	ENOG4108UYE	Lactoylglutathione lyase
HTY51_02530	ENOG4105CHR	reductase
HTY51_02535	ENOG4105C1J	atp-dependent rna helicase
HTY51_02545	ENOG4105C5H	ABC transporter
HTY51_02560	ENOG4105KXX	peptidase s58 dmpa
HTY51_02610	ENOG4105C8Q	Methyl-accepting chemotaxis
HTY51_02615	ENOG4105BZU	Histidine kinase
HTY51_02640	ENOG4105C7W	Xanthine dehydrogenase
HTY51_02655	ENOG4105EYW	Ion transport protein
HTY51_02670	ENOG41080TK	Universal stress protein
HTY51_02675	ENOG4105C8Q	Methyl-accepting chemotaxis
HTY51_02685	ENOG4105BZU	Histidine kinase
HTY51_02690	ENOG4105C08	Histidine kinase
HTY51_02695	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HTY51_02700	ENOG4105DFH	Transport of potassium into the cell (By similarity)
HTY51_02710	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
HTY51_02715	ENOG4105E2X	shikimate dehydrogenase
HTY51_02720	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HTY51_02725	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HTY51_02730	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
HTY51_02735	ENOG4108W9H	Tetr family transcriptional regulator
HTY51_02790	ENOG4105GR3	Histidine kinase
HTY51_02830	ENOG4105CY0	Metallo-Beta-Lactamase
HTY51_02835	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
HTY51_02860	ENOG4105XIV	Mercuric transport protein, periplasmic component
HTY51_02880	ENOG4108IJF	Heavy metal efflux pump, CzcA
HTY51_02890	ENOG4105C59	p-type ATPase
HTY51_02955	ENOG4105KK6	nuclease
HTY51_03005	ENOG4105KA0	thioesterase Superfamily protein
HTY51_03020	ENOG4105TNS	Conserved Protein
HTY51_03045	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HTY51_03050	ENOG4105C8Q	Methyl-accepting chemotaxis
HTY51_03060	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HTY51_03065	ENOG4105D0D	Nitrate reductase 2, gamma subunit
HTY51_03070	ENOG4105R3A	Nitrate reductase
HTY51_03075	ENOG4108IUE	nitrate reductase beta subunit
HTY51_03080	ENOG4105CRU	nitrate reductase, alpha subunit
HTY51_03100	ENOG4105EJC	lysr family transcriptional regulator
HTY51_03115	ENOG4107GFK	fumarate
HTY51_03130	ENOG4105WH1	Two component transcriptional regulator luxr family
HTY51_03135	ENOG4105BZU	Histidine kinase
HTY51_03140	ENOG41068KF	Universal stress protein
HTY51_03145	ENOG410904N	short-chain dehydrogenase reductase
HTY51_03150	ENOG4105D3G	Pseudouridine synthase
HTY51_03170	ENOG410870F	Cyclic nucleotide-binding protein
HTY51_03175	ENOG4108XDN	Transcriptional regulator
HTY51_03190	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HTY51_03225	ENOG4107F9Y	LysR family transcriptional regulator
HTY51_03235	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HTY51_03240	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HTY51_03250	ENOG4105C32	Amino acid ABC transporter (Permease)
HTY51_03255	ENOG4105C0Z	ABC transporter
HTY51_03260	ENOG4108IV0	ABC, transporter
HTY51_03270	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HTY51_03275	ENOG4105C26	Dehydrogenase
HTY51_03305	ENOG4105CGU	Enoyl-CoA hydratase
HTY51_03315	ENOG4105C32	Amino acid ABC transporter (Permease)
HTY51_03325	ENOG4105C0Z	ABC transporter
HTY51_03330	ENOG4108IV0	ABC, transporter
HTY51_03335	ENOG4108YI3	3-hydroxyacyl-CoA-acyl carrier protein transferase
HTY51_03345	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
HTY51_03360	ENOG4105D9M	gamma-glutamylcysteine synthetase
HTY51_03370	ENOG4105C03	ribonuclease
HTY51_03375	ENOG4105EI2	Pseudouridine synthase
HTY51_03390	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HTY51_03400	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HTY51_03405	ENOG4108UHJ	MAF-like protein
HTY51_03410	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HTY51_03415	ENOG4105VGS	50s ribosomal protein l32
HTY51_03420	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HTY51_03425	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HTY51_03430	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HTY51_03435	ENOG4105CHR	reductase
HTY51_03440	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HTY51_03445	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HTY51_03455	ENOG4105EMN	RNA polymerase sigma factor
HTY51_03470	ENOG4105C0H	protease
HTY51_03475	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HTY51_03480	ENOG4105C3F	Signal peptidase i
HTY51_03490	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HTY51_03495	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HTY51_03500	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
HTY51_03505	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HTY51_03510	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HTY51_03515	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
HTY51_03520	ENOG4105C8Q	Methyl-accepting chemotaxis
HTY51_03525	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
HTY51_03530	ENOG4108VKG	metal-dependent hydrolase
HTY51_03550	ENOG4105CRK	lysyL-tRNA synthetase
HTY51_03555	ENOG4108VIA	integral membrane protein
HTY51_03560	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HTY51_03570	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HTY51_03575	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HTY51_03580	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HTY51_03590	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HTY51_03595	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HTY51_03600	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HTY51_03605	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HTY51_03615	ENOG4105BZN	citrate synthase
HTY51_03620	ENOG41060IS	Flavinator of succinate dehydrogenase
HTY51_03625	ENOG4105E33	succinate dehydrogenase
HTY51_03630	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HTY51_03635	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
HTY51_03645	ENOG4105FDP	GntR family transcriptional regulator
HTY51_03650	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HTY51_03660	ENOG4107QIJ	Aconitate hydratase 2
HTY51_03670	ENOG4107GRR	phosphate transport regulator
HTY51_03675	ENOG4107QXV	Phosphate transporter
HTY51_03685	ENOG4105K5M	30s ribosomal protein S16
HTY51_03690	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HTY51_03695	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HTY51_03700	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HTY51_03705	ENOG4105P8F	nudix hydrolase
HTY51_03715	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HTY51_03720	ENOG41090A4	Pterin carbinolamine dehydratase
HTY51_03725	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
HTY51_03730	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HTY51_03735	ENOG4105C1J	atp-dependent rna helicase
HTY51_03750	ENOG4105C2W	permease
HTY51_03755	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HTY51_03770	ENOG4107YCY	Transcriptional regulator
HTY51_03775	ENOG4105VT2	5-hydroxyisourate hydrolase
HTY51_03790	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HTY51_03795	ENOG4105D7T	ABC transporter
HTY51_03800	ENOG4107Z6I	Thiamine biosynthesis protein
HTY51_03815	ENOG4105DND	Transcriptional regulator
HTY51_03820	ENOG4105DG4	malate L-lactate dehydrogenase
HTY51_03825	ENOG4105C26	Dehydrogenase
HTY51_03845	ENOG4105CKI	cobalamin synthesis protein
HTY51_03875	ENOG4108VAU	general secretion pathway protein G
HTY51_03880	ENOG4105D7Q	type ii secretion system
HTY51_03885	ENOG4107QHF	type ii secretion system protein e
HTY51_03920	ENOG4108ZUW	Major pilin subunit
HTY51_03950	ENOG4105C32	Amino acid ABC transporter (Permease)
HTY51_03955	ENOG4108HWW	ABC transporter
HTY51_03960	ENOG4105C0Z	ABC transporter
HTY51_03970	ENOG4108IV0	ABC, transporter
HTY51_03975	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HTY51_03990	ENOG4105BZU	Histidine kinase
HTY51_03995	ENOG4105C4R	Atp-dependent dna helicase
HTY51_04010	ENOG4105CDY	transcriptional regulatory protein
HTY51_04020	ENOG4105CUV	Homoserine Kinase
HTY51_04030	ENOG4105C2M	dna polymerase I
HTY51_04035	ENOG4105CHR	reductase
HTY51_04050	ENOG4105DEN	Luciferase family
HTY51_04060	ENOG4105C1J	atp-dependent rna helicase
HTY51_04065	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
HTY51_04095	ENOG4105KHC	sulfurtransferase
HTY51_04105	ENOG4108M8H	domain protein
HTY51_04115	ENOG41082UU	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HTY51_04120	ENOG4105CTB	Polyprenyl synthetase
HTY51_04125	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HTY51_04130	ENOG4105CH5	extracellular solute-binding protein, family 7
HTY51_04135	ENOG4105CH5	extracellular solute-binding protein, family 7
HTY51_04140	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HTY51_04150	ENOG4105E6M	Sulphatase-modifying factor protein
HTY51_04165	ENOG4108JJB	ABC transporter
HTY51_04175	ENOG4108VJC	ABC transporter, periplasmic molybdate-binding protein
HTY51_04210	ENOG4105ERH	Fumarylacetoacetate hydrolase
HTY51_04215	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
HTY51_04255	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HTY51_04260	ENOG4108MG3	formate dehydrogenase
HTY51_04265	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
HTY51_04270	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
HTY51_04275	ENOG4105EM7	Selenocysteine-specific translation elongation factor
HTY51_04285	ENOG4108UR0	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HTY51_04305	ENOG4105CC0	LysR family Transcriptional regulator
HTY51_04320	ENOG4105F1N	DNA alkylation repair
HTY51_04340	ENOG4105R8A	Heat shock protein
HTY51_04345	ENOG4105NXH	GreA GreB family elongation factor
HTY51_04350	ENOG41061H0	Monooxygenase
HTY51_04395	ENOG4107QIZ	NADH dehydrogenase
HTY51_04400	ENOG4108JB9	formate dehydrogenase
HTY51_04405	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HTY51_04415	ENOG4108K3A	Glutathione S-transferase
HTY51_04430	ENOG4105E5M	Multidrug resistance protein D
HTY51_04445	ENOG4108XIB	electron transport protein ysaA
HTY51_04450	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
HTY51_04485	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
HTY51_04490	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HTY51_04500	ENOG41068KF	Universal stress protein
HTY51_04515	ENOG4108KDI	dmso reductase anchor subunit
HTY51_04520	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HTY51_04525	ENOG4105DB1	molybdopterin oxidoreductase
HTY51_04530	ENOG4105BZU	Histidine kinase
HTY51_04535	ENOG4105WH1	Two component transcriptional regulator luxr family
HTY51_04545	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HTY51_04560	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HTY51_04570	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HTY51_04595	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
HTY51_04600	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
HTY51_04605	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
HTY51_04610	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
HTY51_04615	ENOG4105PJW	Sulfite reductase dissimilatory-type beta subunit
HTY51_04620	ENOG4105CY1	sulfite reductase, dissimilatory-type alpha subunit
HTY51_04630	ENOG4108XKQ	CRISPR-associated protein, Cas6-related
HTY51_04635	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
HTY51_04675	ENOG4107Z6W	Protein CrcB homolog
HTY51_04685	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HTY51_04720	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
HTY51_04725	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HTY51_04730	ENOG4105CFV	Tetratricopeptide repeat protein
HTY51_04740	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HTY51_04745	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HTY51_04750	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HTY51_04765	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HTY51_04770	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HTY51_04775	ENOG4105UYK	outer membrane protein a
HTY51_04780	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HTY51_04785	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HTY51_04795	ENOG4105I08	Pseudouridine synthase
HTY51_04835	ENOG4105CUX	Signal transduction histidine kinase
HTY51_04840	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HTY51_04860	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HTY51_04870	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HTY51_04885	ENOG4105E39	Enoyl-CoA hydratase
HTY51_04915	ENOG4105CQB	FAD linked oxidase domain protein
HTY51_04925	ENOG4107S2Z	UPF0761 membrane protein
HTY51_04945	ENOG4105F8J	Adenylate Guanylate cyclase
HTY51_04965	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HTY51_04975	ENOG4108IJ8	ABC transporter
HTY51_04995	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HTY51_05000	ENOG4105MP9	class II Aldolase
HTY51_05005	ENOG41084KP	4-oxalocrotonate tautomerase
HTY51_05015	ENOG41069NU	Nitroreductase
HTY51_05020	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HTY51_05025	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HTY51_05030	ENOG4105CFP	Peptidase U32
HTY51_05035	ENOG4108YZN	class I peptide chain release factor
HTY51_05045	ENOG4108Z33	Thiol disulfide Interchange Protein
HTY51_05100	ENOG4105VFU	Rna-binding protein
HTY51_05105	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HTY51_05120	ENOG4105BZU	Histidine kinase
HTY51_05130	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
HTY51_05135	ENOG4105C9Q	fumarate hydratase class II
HTY51_05155	ENOG4105BZU	Histidine kinase
HTY51_05185	ENOG4108W5M	transcriptional regulator
HTY51_05190	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HTY51_05195	ENOG4105CHR	reductase
HTY51_05200	ENOG4105DAN	ATP-dependent protease
HTY51_05235	ENOG4107QNJ	CoA-transferase subunit B
HTY51_05270	ENOG4105C26	Dehydrogenase
HTY51_05275	ENOG4108JPW	Aminotransferase
HTY51_05285	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
HTY51_05290	ENOG4105D81	ABC transporter, permease
HTY51_05295	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HTY51_05300	ENOG4107TYH	extracellular solute-binding protein family 1
HTY51_05305	ENOG4108M0I	Transcriptional regulator
HTY51_05310	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HTY51_05315	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HTY51_05330	ENOG4108KS2	transglutaminase domain protein
HTY51_05350	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HTY51_05355	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
HTY51_05360	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HTY51_05370	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HTY51_05375	ENOG4105C5R	Aminotransferase
HTY51_05385	ENOG4105CQB	FAD linked oxidase domain protein
HTY51_05410	ENOG4106HNH	Acyl-transferase
HTY51_05420	ENOG4107YZX	Universal stress protein
HTY51_05430	ENOG4105R8C	Transcriptional regulator
HTY51_05450	ENOG4107TPS	domain protein
HTY51_05455	ENOG4105CUC	YeeE YedE family protein
HTY51_05490	ENOG4105BZU	Histidine kinase
HTY51_05500	ENOG41066DG	(EAL) domain protein
HTY51_05505	ENOG4108V3W	Chemotaxis protein, CheW
HTY51_05515	ENOG4105BZU	Histidine kinase
HTY51_05525	ENOG4105BZU	Histidine kinase
HTY51_05540	ENOG4105D3G	Pseudouridine synthase
HTY51_05545	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HTY51_05550	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HTY51_05555	ENOG4108QDE	fad dependent oxidoreductase
HTY51_05560	ENOG4105EQ1	Transcriptional regulator
HTY51_05580	ENOG4105EUB	pirin domain protein
HTY51_05585	ENOG4105C8Q	Methyl-accepting chemotaxis
HTY51_05590	ENOG4105BZU	Histidine kinase
HTY51_05600	ENOG4105C72	UPF0176 protein
HTY51_05615	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HTY51_05625	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HTY51_05640	ENOG4108NVM	synthesis repressor PhaR
HTY51_05645	ENOG4108Z86	Glutamine amidotransferase
HTY51_05650	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HTY51_05660	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HTY51_05665	ENOG4105CHR	reductase
HTY51_05670	ENOG4107TTQ	Alpha beta hydrolase fold
HTY51_05680	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HTY51_05685	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HTY51_05690	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
HTY51_05695	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HTY51_05705	ENOG4105CE9	30S ribosomal protein S2
HTY51_05710	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HTY51_05715	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HTY51_05720	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HTY51_05730	ENOG4105KNE	Phosphatidate cytidylyltransferase
HTY51_05735	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HTY51_05740	ENOG4105DZP	Membrane-associated zinc metalloprotease
HTY51_05745	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HTY51_05755	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HTY51_05760	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HTY51_05765	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HTY51_05770	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HTY51_05775	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HTY51_05780	ENOG4108RWN	rrna methyltransferase
HTY51_05790	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HTY51_05795	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HTY51_05805	ENOG4105HBR	Rna-binding protein
HTY51_05810	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HTY51_05815	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HTY51_05820	ENOG4105EEI	dihydropteroate synthase
HTY51_05825	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HTY51_05830	ENOG4105K89	arsenate reductase
HTY51_05835	ENOG4105D6J	arsenicaL-resistance protein
HTY51_05870	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HTY51_05890	ENOG4105BZU	Histidine kinase
HTY51_05895	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HTY51_05915	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HTY51_05920	ENOG4105DJ4	phosphatidylserine decarboxylase
HTY51_05935	ENOG4108UJV	acyl-CoA thioesterase i
HTY51_05940	ENOG4105C9X	ppx gppa phosphatase
HTY51_05950	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
HTY51_05955	ENOG4105C8U	phosphate abc transporter
HTY51_05960	ENOG4105E2Z	phosphate ABC transporter (Permease
HTY51_05965	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HTY51_05975	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HTY51_05980	ENOG4105BZU	Histidine kinase
HTY51_05990	ENOG4107QI1	Mate efflux family protein
HTY51_06000	ENOG4105NRA	50s ribosomal protein l31 type b
HTY51_06005	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HTY51_06010	ENOG4105K63	Thioredoxin
HTY51_06020	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
HTY51_06025	ENOG4105CBX	hi0933 family
HTY51_06040	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HTY51_06045	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HTY51_06050	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HTY51_06060	ENOG4105D2X	ABC transporter substrate-binding protein
HTY51_06080	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HTY51_06085	ENOG4105E9H	Lytic Murein transglycosylase
HTY51_06090	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HTY51_06100	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HTY51_06105	ENOG410624X	efflux transporter, rnd family, mfp subunit
HTY51_06110	ENOG4105BZS	acriflavin resistance protein
HTY51_06120	ENOG4108M8H	domain protein
HTY51_06130	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HTY51_06135	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HTY51_06170	ENOG4105F0N	pyrophosphate phospho-hydrolase
HTY51_06175	ENOG4108V3W	Chemotaxis protein, CheW
HTY51_06180	ENOG4105C8Q	Methyl-accepting chemotaxis
HTY51_06200	ENOG4108URH	decarboxylase
HTY51_06205	ENOG41080IJ	Diacylglycerol kinase
HTY51_06225	ENOG4105JVQ	RNA Polymerase
HTY51_06230	ENOG4105C7K	acetolactate synthase
HTY51_06235	ENOG4108ZP8	Acetolactate synthase small subunit
HTY51_06240	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HTY51_06245	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HTY51_06250	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HTY51_06255	ENOG41061WM	D-Alanyl-D-Alanine
HTY51_06260	ENOG4107HP6	Transcriptional regulator
HTY51_06265	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
HTY51_06270	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HTY51_06285	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HTY51_06295	ENOG4108TEB	UPF0114 protein
HTY51_06300	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HTY51_06305	ENOG4105W2Z	cytochrome C, class I
HTY51_06315	ENOG4105C01	Dihydroxy-acid dehydratase
HTY51_06320	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HTY51_06325	ENOG4105DRR	Transcriptional regulator, GntR family
HTY51_06340	ENOG4108UKI	Enoyl-CoA hydratase
HTY51_06345	ENOG4105CEY	Amp-dependent synthetase and ligase
HTY51_06355	ENOG4107YZX	Universal stress protein
HTY51_06360	ENOG4105C59	p-type ATPase
HTY51_06370	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
HTY51_06405	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HTY51_06410	ENOG4105D4P	Coproporphyrinogen iii oxidase
HTY51_06420	ENOG4105CND	Glycosyl transferase, family 2
HTY51_06430	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HTY51_06435	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HTY51_06465	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HTY51_06485	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HTY51_06490	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HTY51_06510	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HTY51_06515	ENOG4105BZU	Histidine kinase
HTY51_06520	ENOG4105DRR	Transcriptional regulator, GntR family
HTY51_06535	ENOG4105DJT	lAO AO transport system ATPase
HTY51_06540	ENOG4107QX3	carboxylase
HTY51_06560	ENOG4105C8Q	Methyl-accepting chemotaxis
HTY51_06565	ENOG4108R3D	Electron transport complex
HTY51_06575	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HTY51_06590	ENOG4105C1J	atp-dependent rna helicase
HTY51_06600	ENOG4105D78	K07001 NTE family protein
HTY51_06605	ENOG4105BZU	Histidine kinase
HTY51_06620	ENOG4105CGF	Aromatic amino acid aminotransferase
HTY51_06630	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HTY51_06635	ENOG4105C3J	Cysteine desulfurase
HTY51_06640	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
HTY51_06650	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
HTY51_06655	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
HTY51_06660	ENOG4108ZIT	Ferredoxin, 2FE-2S
HTY51_06665	ENOG4107RZZ	dna polymerase iii epsilon subunit
HTY51_06690	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HTY51_06695	ENOG4105BZS	acriflavin resistance protein
HTY51_06700	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HTY51_06705	ENOG4105D5U	fad dependent oxidoreductase
HTY51_06730	ENOG4105EJC	lysr family transcriptional regulator
HTY51_06735	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HTY51_06740	ENOG4105E66	phosphoriboisomerase A
HTY51_06750	ENOG4105DGW	oligopeptidase A
HTY51_06755	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HTY51_06760	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HTY51_06765	ENOG4105BZU	Histidine kinase
HTY51_06770	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HTY51_06775	ENOG4107QSN	dihydrolipoamide acetyltransferase
HTY51_06780	ENOG4107QN2	dihydrolipoyl dehydrogenase
HTY51_06810	ENOG4105K4H	Nlp p60 protein
HTY51_06815	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
HTY51_06835	ENOG4105RD8	TRAP dicarboxylate transporter
HTY51_06840	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HTY51_06865	ENOG41061CK	Antibiotic biosynthesis monooxygenase
HTY51_06870	ENOG4105BZU	Histidine kinase
HTY51_06880	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HTY51_06890	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
HTY51_06895	ENOG4105CHU	acetyl-coa acetyltransferase
HTY51_06900	ENOG4105CHR	reductase
HTY51_06910	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
HTY51_06925	ENOG4105CF7	AraC family transcriptional regulator
HTY51_06930	ENOG4105C2C	drug resistance transporter, Bcr CflA
HTY51_06940	ENOG4108UT2	hemolysin iii
HTY51_06955	ENOG4108UIN	ybak prolyl-trna synthetase associated region
HTY51_06960	ENOG4107RUY	(E1 component), alpha subunit
HTY51_06965	ENOG4105CPP	Dehydrogenase, E1 component
HTY51_06995	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HTY51_07000	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HTY51_07005	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HTY51_07015	ENOG4105CFN	oxalyl-CoA decarboxylase
HTY51_07045	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HTY51_07050	ENOG4105HF0	Membrane
HTY51_07055	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
HTY51_07065	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HTY51_07075	ENOG4108HUF	Transporter
HTY51_07080	ENOG4105EHG	Permease protein
HTY51_07085	ENOG4105E0A	ABC, transporter
HTY51_07090	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HTY51_07095	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HTY51_07105	ENOG4105CSM	endonuclease III
HTY51_07120	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HTY51_07150	ENOG4105E8R	UPF0173 metal-dependent hydrolase
HTY51_07155	ENOG4105E90	ABC transporter
HTY51_07165	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HTY51_07235	ENOG4105CAH	Chromate
HTY51_07245	ENOG4105BZU	Histidine kinase
HTY51_07260	ENOG4105BZU	Histidine kinase
HTY51_07265	ENOG4105CCT	upf0313 protein
HTY51_07270	ENOG4108MXC	l-carnitine dehydratase bile acid-inducible protein F
HTY51_07275	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HTY51_07280	ENOG4105BZU	Histidine kinase
HTY51_07285	ENOG4105BZU	Histidine kinase
HTY51_07310	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HTY51_07320	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
HTY51_07325	ENOG4107HP6	Transcriptional regulator
HTY51_07340	ENOG4105CFP	Peptidase U32
HTY51_07345	ENOG4107T8T	UPF0173 metal-dependent hydrolase
HTY51_07350	ENOG4107TF3	peptidylprolyl cis-trans isomerase
HTY51_07360	ENOG4107835	probably involved in intracellular septation (By similarity)
HTY51_07365	ENOG4105E0X	reductase
HTY51_07370	ENOG4105CNG	UPF0061 protein
HTY51_07375	ENOG4105CEY	Amp-dependent synthetase and ligase
HTY51_07385	ENOG4105C32	Amino acid ABC transporter (Permease)
HTY51_07395	ENOG4105C0Z	ABC transporter
HTY51_07400	ENOG4108IV0	ABC, transporter
HTY51_07405	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HTY51_07410	ENOG4105CHU	acetyl-coa acetyltransferase
HTY51_07415	ENOG4105CSU	acyl-Coa dehydrogenase
HTY51_07425	ENOG4105CHR	reductase
HTY51_07435	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HTY51_07450	ENOG4105BZU	Histidine kinase
HTY51_07460	ENOG4105BZM	domain protein
HTY51_07500	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HTY51_07505	ENOG4105HHA	aminodeoxychorismate lyase
HTY51_07510	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HTY51_07515	ENOG4107QRG	dna polymerase iii
HTY51_07525	ENOG4105F8V	Hydrolase, tatD family
HTY51_07540	ENOG4105CZX	twitching motility protein
HTY51_07545	ENOG4107QHF	type ii secretion system protein e
HTY51_07560	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
HTY51_07585	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HTY51_07590	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HTY51_07600	ENOG4105VDB	UPF0125 protein
HTY51_07605	ENOG4108Z1B	Cyclase dehydrase
HTY51_07610	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HTY51_07620	ENOG4105E39	Enoyl-CoA hydratase
HTY51_07630	ENOG4105CI3	gtp-binding protein typa
HTY51_07635	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HTY51_07640	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HTY51_07645	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HTY51_07650	ENOG4105CHV	Transcription elongation factor NusA
HTY51_07655	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HTY51_07660	ENOG4108JQ5	ABC transporter
HTY51_07665	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
HTY51_07670	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
HTY51_07675	ENOG4105E43	Extracellular solute-binding protein, family 5
HTY51_07680	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HTY51_07685	ENOG4105CXN	decarboxylase
HTY51_07700	ENOG4108S4H	thioesterase Superfamily protein
HTY51_07705	ENOG4105KK6	nuclease
HTY51_07730	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HTY51_07735	ENOG4108M8S	permease YjgP YjgQ family protein
HTY51_07750	ENOG4106YN8	Prenyltransferase
HTY51_07800	ENOG4107R11	Transcriptional regulator
HTY51_07805	ENOG4105CHM	Aminotransferase
HTY51_07850	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HTY51_07885	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HTY51_07890	ENOG4105CQ7	ATP-dependent helicase
HTY51_07895	ENOG4108EKC	n-acetylglutamate synthase
HTY51_07970	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
HTY51_08000	ENOG4105BZU	Histidine kinase
HTY51_08010	ENOG4105BZU	Histidine kinase
HTY51_08020	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HTY51_08025	ENOG4105C8Q	Methyl-accepting chemotaxis
HTY51_08030	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HTY51_08035	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
HTY51_08045	ENOG4108RVA	ribokinase
HTY51_08055	ENOG4107TSN	permease
HTY51_08075	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HTY51_08085	ENOG4108Z4U	Ferredoxin
HTY51_08090	ENOG4105CAY	ferredoxin--nadp reductase
HTY51_08105	ENOG4105WHD	thiamine biosynthesis protein ThiS
HTY51_08110	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HTY51_08115	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HTY51_08155	ENOG4105BZU	Histidine kinase
HTY51_08160	ENOG4108ETH	Formylglycinamide ribotide synthetase
HTY51_08165	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HTY51_08175	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HTY51_08180	ENOG4105WD1	Membrane
HTY51_08185	ENOG4105C8Q	Methyl-accepting chemotaxis
HTY51_08200	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HTY51_08210	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HTY51_08220	ENOG4105BZU	Histidine kinase
HTY51_08230	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HTY51_08235	ENOG4105CZX	twitching motility protein
HTY51_08240	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HTY51_08245	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HTY51_08250	ENOG4105C5H	ABC transporter
HTY51_08280	ENOG4105CUZ	uba thif-type nad fad binding protein
HTY51_08285	ENOG4105CUC	YeeE YedE family protein
HTY51_08295	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HTY51_08300	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HTY51_08320	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HTY51_08350	ENOG4107RJ7	Glycosyl transferase (Group 1
HTY51_08355	ENOG4105C03	ribonuclease
HTY51_08360	ENOG4108Z03	MAF-like protein
HTY51_08365	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HTY51_08370	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HTY51_08375	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HTY51_08380	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HTY51_08390	ENOG4105C12	Phosphoribosylglycinamide synthetase
HTY51_08395	ENOG4105CDY	transcriptional regulatory protein
HTY51_08400	ENOG4105D7A	ATP-binding protein
HTY51_08410	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HTY51_08420	ENOG4105DTD	Dehydrogenase
HTY51_08425	ENOG4105D9P	serine threonine protein kinase
HTY51_08440	ENOG4105E0F	Histidine kinase
HTY51_08445	ENOG4108ECM	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
HTY51_08450	ENOG4108ECM	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
HTY51_08455	ENOG4108JA2	transcriptioN-repair coupling factor
HTY51_08465	ENOG4105EAC	phosphoserine phosphatase
HTY51_08470	ENOG4107QX9	Thiol disulfide interChange protein
HTY51_08480	ENOG4105DGI	Alkaline phosphatase
HTY51_08495	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HTY51_08505	ENOG4108I0Y	(ABC) transporter
HTY51_08510	ENOG4108UJV	acyl-CoA thioesterase i
HTY51_08515	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
HTY51_08530	ENOG4105NX3	Membrane
HTY51_08550	ENOG4105CJ1	ABC, transporter
HTY51_08560	ENOG4105C28	cystathionine
HTY51_08565	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
HTY51_08570	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HTY51_08575	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
HTY51_08585	ENOG4105EPW	hflc protein
HTY51_08590	ENOG4107QJR	hflk protein
HTY51_08595	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HTY51_08600	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HTY51_08605	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HTY51_08620	ENOG4105CUT	histidyl-tRNA synthetase
HTY51_08625	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HTY51_08640	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HTY51_08645	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HTY51_08650	ENOG4105FE9	pseudouridine synthase
HTY51_08655	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HTY51_08660	ENOG4105C34	Pseudouridine synthase
HTY51_08665	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HTY51_08670	ENOG4105DVT	helicase
HTY51_08690	ENOG4105D6Z	AFG1 family ATPase
HTY51_08695	ENOG4107QN2	dihydrolipoyl dehydrogenase
HTY51_08700	ENOG4105KPY	Small multidrug resistance protein
HTY51_08705	ENOG4105C7S	Dehydrogenase
HTY51_08710	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HTY51_08715	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HTY51_08725	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HTY51_08760	ENOG4105QPS	Monooxygenase
HTY51_08800	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HTY51_08805	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HTY51_08810	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HTY51_08815	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HTY51_08820	ENOG4105VJV	50s ribosomal protein L35
HTY51_08825	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HTY51_08830	ENOG4105C22	threonyL-tRNA synthetase
HTY51_08840	ENOG4108I9X	Isocitrate lyase
HTY51_08880	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HTY51_08915	ENOG4105SWR	response regulator
HTY51_08925	ENOG4105DIJ	Phosphoethanolamine transferase
HTY51_08935	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HTY51_08945	ENOG4105CYM	Glutathione S-transferase
HTY51_08950	ENOG4105KME	endoribonuclease L-psp
HTY51_08955	ENOG4108TY5	Exhibits lactonase activity. Acts in cells with perturbed membrane integrity and is possibly related to the membrane homeostasis
HTY51_08965	ENOG4105YES	addiction module antidote protein
HTY51_08970	ENOG4105VUH	addiction module killer protein
HTY51_08995	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HTY51_09005	ENOG4105VBA	Cytochrome
HTY51_09020	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HTY51_09025	ENOG41061H0	Monooxygenase
HTY51_09040	ENOG4105EJC	lysr family transcriptional regulator
HTY51_09045	ENOG4108ZAF	Molybdopterin
HTY51_09050	ENOG4105M00	molybdopterin converting factor, subunit 1
HTY51_09055	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HTY51_09060	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
HTY51_09070	ENOG4105D6E	homoserine dehydrogenase
HTY51_09075	ENOG4105CHM	Aminotransferase
HTY51_09085	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HTY51_09090	ENOG4108IAB	Phoh family
HTY51_09095	ENOG4105CDU	Replicative dna helicase
HTY51_09100	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HTY51_09105	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HTY51_09115	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HTY51_09120	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HTY51_09125	ENOG41080XP	Cbs domain
HTY51_09130	ENOG4107QN1	sodium solute
HTY51_09155	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HTY51_09160	ENOG4105E0K	tonB-dependent siderophore receptor
HTY51_09165	ENOG4107E2E	PKHD-type hydroxylase
HTY51_09185	ENOG4105M8F	Biopolymer transport protein exbD tolR
HTY51_09195	ENOG4108ZJF	Glcg protein
HTY51_09200	ENOG4108MN8	Membrane
HTY51_09210	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HTY51_09220	ENOG4108WZ2	response regulator
HTY51_09225	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HTY51_09235	ENOG4105BZU	Histidine kinase
HTY51_09240	ENOG4105BZU	Histidine kinase
HTY51_09245	ENOG4105C8Q	Methyl-accepting chemotaxis
HTY51_09250	ENOG4105DHT	Metal Dependent Phosphohydrolase
HTY51_09255	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HTY51_09260	ENOG4108K5P	(LipO)protein
HTY51_09265	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HTY51_09270	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HTY51_09285	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HTY51_09300	ENOG4107RT3	EamA-like transporter family
HTY51_09310	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HTY51_09315	ENOG4105CJB	Exodeoxyribonuclease I
HTY51_09325	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HTY51_09330	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
HTY51_09335	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HTY51_09355	ENOG41067TZ	transcriptional regulator, MarR family
HTY51_09365	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
HTY51_09370	ENOG4105C5I	Dehydrogenase
HTY51_09390	ENOG4108WFY	phasin family
HTY51_09395	ENOG4105D78	K07001 NTE family protein
HTY51_09405	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HTY51_09410	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HTY51_09420	ENOG4105E9K	Isocitrate dehydrogenase
HTY51_09425	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HTY51_09430	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HTY51_09440	ENOG4109015	Biopolymer transport protein exbD tolR
HTY51_09445	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HTY51_09450	ENOG4105W49	UPF0434 protein
HTY51_09455	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HTY51_09460	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HTY51_09480	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HTY51_09490	ENOG4108JQ1	Dehydrogenase
HTY51_09495	ENOG4105IU3	Glutathione S-transferase
HTY51_09500	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HTY51_09505	ENOG4108UKI	Enoyl-CoA hydratase
HTY51_09510	ENOG4105IJJ	transcriptional regulator, crp fnr family
HTY51_09525	ENOG4105CYM	Glutathione S-transferase
HTY51_09530	ENOG4105CPI	Metal Dependent Phosphohydrolase
HTY51_09545	ENOG4105GVR	general secretion pathway protein D
HTY51_09570	ENOG4106855	Competence protein
HTY51_09575	ENOG4105D7Q	type ii secretion system
HTY51_09580	ENOG4107QHF	type ii secretion system protein e
HTY51_09610	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HTY51_09615	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HTY51_09620	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HTY51_09625	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HTY51_09635	ENOG4105BZS	acriflavin resistance protein
HTY51_09640	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HTY51_09650	ENOG4105FE1	phytoene synthase
HTY51_09655	ENOG4107S11	squalene-associated FAD-dependent desaturase
HTY51_09665	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
HTY51_09670	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HTY51_09675	ENOG4108TGY	Glutathione S-transferase
HTY51_09690	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HTY51_09700	ENOG4108IV0	ABC, transporter
HTY51_09705	ENOG4105C0Z	ABC transporter
HTY51_09715	ENOG4108JUA	Transcriptional regulator
HTY51_09720	ENOG4105VEJ	Heat shock protein
HTY51_09730	ENOG4105CFH	Aspartokinase
HTY51_09735	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HTY51_09740	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HTY51_09750	ENOG4105C8N	cysteinyl-tRNA synthetase
HTY51_09780	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HTY51_09785	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
HTY51_09795	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
HTY51_09800	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HTY51_09805	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HTY51_09810	ENOG4106855	Competence protein
HTY51_09815	ENOG4105CWU	Biogenesis protein
HTY51_09840	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HTY51_09855	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HTY51_09860	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HTY51_09865	ENOG4107YIM	Involved in the transcription termination process (By similarity)
HTY51_09870	ENOG4105CHM	Aminotransferase
HTY51_09875	ENOG4107YD3	Thioesterase
HTY51_09880	ENOG4105E02	MotA TolQ exbB proton channel
HTY51_09885	ENOG4105M8F	Biopolymer transport protein exbD tolR
HTY51_09915	ENOG4105E0F	Histidine kinase
HTY51_09920	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HTY51_09935	ENOG4105BZU	Histidine kinase
HTY51_09940	ENOG4105D85	methylase
HTY51_09950	ENOG4105CPC	Aldo Keto reductase
HTY51_09970	ENOG4105GAK	amidohydrolase 2
HTY51_09985	ENOG4105KHM	amidohydrolase 2
HTY51_10000	ENOG4105E2X	shikimate dehydrogenase
HTY51_10005	ENOG4107T8T	UPF0173 metal-dependent hydrolase
HTY51_10015	ENOG4108IV0	ABC, transporter
HTY51_10020	ENOG4105C0Z	ABC transporter
HTY51_10060	ENOG4105E9F	Enoyl-CoA hydratase
HTY51_10080	ENOG4105C32	Amino acid ABC transporter (Permease)
HTY51_10085	ENOG4105C0Z	ABC transporter
HTY51_10090	ENOG4108IV0	ABC, transporter
HTY51_10100	ENOG4105CSU	acyl-Coa dehydrogenase
HTY51_10120	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HTY51_10125	ENOG4105CFG	Acts as a chaperone (By similarity)
HTY51_10130	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HTY51_10135	ENOG4105CY0	Metallo-Beta-Lactamase
HTY51_10145	ENOG4105BZU	Histidine kinase
HTY51_10155	ENOG4105CSU	acyl-Coa dehydrogenase
HTY51_10160	ENOG4105C10	Electron transfer flavoprotein
HTY51_10165	ENOG4105BZJ	Electron transfer flavoprotein
HTY51_10170	ENOG4105EGS	Mechanosensitive ion channel
HTY51_10185	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HTY51_10195	ENOG4108EC8	DNA internalization-related competence protein ComEC
HTY51_10205	ENOG4105CVE	Lytic murein transglycosylase
HTY51_10210	ENOG4105F8C	transglutaminase domain-containing protein
HTY51_10220	ENOG4105C8Q	Methyl-accepting chemotaxis
HTY51_10225	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HTY51_10230	ENOG4105DJ0	Poly(A) Polymerase
HTY51_10240	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HTY51_10245	ENOG4105C02	permease
HTY51_10250	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HTY51_10270	ENOG4105CJR	Integral membrane protein (MviN
HTY51_10275	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
HTY51_10285	ENOG4105C8Y	Acetylornithine aminotransferase
HTY51_10290	ENOG4105DBV	ornithine carbamoyltransferase
HTY51_10300	ENOG4105MSY	salicylate hydroxylase
HTY51_10305	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HTY51_10310	ENOG4105E4C	Lytic transglycosylase catalytic
HTY51_10315	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HTY51_10335	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HTY51_10340	ENOG4105GJM	(LipO)protein
HTY51_10350	ENOG4105EZE	Cupin 4 family protein
HTY51_10355	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HTY51_10360	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HTY51_10365	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HTY51_10370	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HTY51_10375	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HTY51_10385	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HTY51_10390	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HTY51_10400	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HTY51_10405	ENOG4108Z0R	Transferase
HTY51_10410	ENOG4105ED9	Protein of unknown function (DUF455)
HTY51_10415	ENOG4105D58	Diguanylate phosphodiesterase
HTY51_10425	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HTY51_10450	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HTY51_10455	ENOG4105K8N	protein family UPF0079, ATPase
HTY51_10460	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HTY51_10475	ENOG4105DQR	SNARE associated Golgi
HTY51_10480	ENOG4105CKW	Inner membrane protein yedI
HTY51_10485	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HTY51_10490	ENOG4105VFE	sira family
HTY51_10495	ENOG4107YU2	histidine triad (hIT) protein
HTY51_10505	ENOG4105C2C	drug resistance transporter, Bcr CflA
HTY51_10510	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HTY51_10525	ENOG4105VN1	Heat shock protein
HTY51_10540	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HTY51_10555	ENOG4105BZ1	(ABC) transporter
HTY51_10580	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HTY51_10585	ENOG4105C8S	subunit m
HTY51_10595	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HTY51_10600	ENOG4105DF2	NADH dehydrogenase subunit j
HTY51_10605	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HTY51_10610	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HTY51_10615	ENOG4108IEH	NADH dehydrogenase subunit g
HTY51_10620	ENOG4107QIZ	NADH dehydrogenase
HTY51_10625	ENOG4105GKE	subunit e
HTY51_10630	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HTY51_10635	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HTY51_10640	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HTY51_10645	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HTY51_10655	ENOG4107EJC	Preprotein translocase subunit SecG
HTY51_10660	ENOG4105CP7	Triose-phosphate isomerase
HTY51_10670	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HTY51_10675	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HTY51_10695	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HTY51_10700	ENOG4105CHR	reductase
HTY51_10710	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
HTY51_10715	ENOG4105D7T	ABC transporter
HTY51_10735	ENOG4105I5W	Transporter
HTY51_10745	ENOG4105D7T	ABC transporter
HTY51_10770	ENOG4105D9P	serine threonine protein kinase
HTY51_10775	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HTY51_10785	ENOG4105WZK	nitrite reductase NADPH small subunit
HTY51_10790	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HTY51_10795	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HTY51_10810	ENOG4105CBX	hi0933 family
HTY51_10815	ENOG4105VCC	30S ribosomal protein S21
HTY51_10820	ENOG4105KTH	gatB Yqey
HTY51_10835	ENOG4108594	Permease of the drug metabolite transporter
HTY51_10840	ENOG4105DMT	epimerase dehydratase
HTY51_10845	ENOG4105C09	Bile acid
HTY51_10850	ENOG4105H3G	oxidoreductase
HTY51_10855	ENOG4107FW0	short-chain dehydrogenase reductase
HTY51_10860	ENOG4108FUF	Transcriptional regulator, IclR family
HTY51_10870	ENOG4105EQX	glucarate dehydratase
HTY51_10880	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
HTY51_10885	ENOG4107YCY	Transcriptional regulator
HTY51_10890	ENOG4105E9Z	Nad-dependent epimerase dehydratase
HTY51_10895	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HTY51_10905	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HTY51_10910	ENOG4105EQX	glucarate dehydratase
HTY51_10920	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HTY51_10925	ENOG4105CTX	dehydratase
HTY51_10930	ENOG4105BZU	Histidine kinase
HTY51_10940	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HTY51_10945	ENOG4105N42	UPF0307 protein
HTY51_10950	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HTY51_10955	ENOG4108594	Permease of the drug metabolite transporter
HTY51_10960	ENOG4105D7W	serine acetyltransferase
HTY51_10970	ENOG4105ECY	inositol monophosphatase
HTY51_10985	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
HTY51_11000	ENOG4105E98	transcriptional regulator DeoR family
HTY51_11005	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HTY51_11010	ENOG4108IJ9	(ABC) transporter
HTY51_11040	ENOG410624X	efflux transporter, rnd family, mfp subunit
HTY51_11045	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HTY51_11080	ENOG4105D9P	serine threonine protein kinase
HTY51_11090	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HTY51_11100	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HTY51_11115	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HTY51_11120	ENOG4105C19	ABC transporter
HTY51_11140	ENOG4108HRK	Histidine kinase
HTY51_11145	ENOG4108VAC	response regulator
HTY51_11160	ENOG4105CX6	glutaminyL-tRNA synthetase
HTY51_11305	ENOG4105CHR	reductase
HTY51_11310	ENOG4105GAK	amidohydrolase 2
HTY51_11315	ENOG4105EF7	Transcriptional regulator
HTY51_11345	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
HTY51_11370	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HTY51_11375	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HTY51_11385	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
HTY51_11390	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HTY51_11400	ENOG4105D1H	recombination factor protein RarA
HTY51_11405	ENOG4105C32	Amino acid ABC transporter (Permease)
HTY51_11410	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HTY51_11415	ENOG4105C0Z	ABC transporter
HTY51_11420	ENOG4108IV0	ABC, transporter
HTY51_11430	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
HTY51_11480	ENOG4105C6T	cysteine synthase
HTY51_11490	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HTY51_11495	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HTY51_11510	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
HTY51_11530	ENOG4105DR9	pseudouridine synthase
HTY51_11535	ENOG4105D1Q	UPF0246 protein
HTY51_11540	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HTY51_11545	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HTY51_11555	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HTY51_11590	ENOG4105DUM	transcriptional regulator, lysR family
HTY51_11595	ENOG4105HMI	Membrane
HTY51_11645	ENOG4105NXP	Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis (By similarity)
HTY51_11665	ENOG41090ED	Protein with unknown function (DUF469)
HTY51_11690	ENOG4105CHR	reductase
HTY51_11700	ENOG4107HP6	Transcriptional regulator
HTY51_11730	ENOG4105CKI	cobalamin synthesis protein
HTY51_11735	ENOG4107HP6	Transcriptional regulator
HTY51_11755	ENOG4107BVJ	4,5-dihydroxyphthalate decarboxylase
HTY51_11765	ENOG4105E3B	Multicopper oxidase
HTY51_11795	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HTY51_11830	ENOG4105DMF	Dehydrogenase
HTY51_11835	ENOG4105CTQ	phosphohexokinase
HTY51_11845	ENOG4105CH7	arginosuccinase
HTY51_11850	ENOG4108HRK	Histidine kinase
HTY51_11855	ENOG4108NEV	two component transcriptional regulator, LytTR family
HTY51_11860	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HTY51_11865	ENOG4105CNU	cell division protein FtsK
HTY51_11870	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
HTY51_11880	ENOG4105KDC	50s ribosomal protein l28
HTY51_11885	ENOG4105W0E	50S ribosomal protein L33
HTY51_11900	ENOG4105D4A	Cell wall formation (By similarity)
HTY51_11905	ENOG4108VPT	UPF0234 protein
HTY51_11920	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HTY51_11925	ENOG4105BZU	Histidine kinase
HTY51_11930	ENOG4108Z66	YbaK ebsC protein
HTY51_11940	ENOG4107RGH	Aldehyde dehydrogenase
HTY51_11945	ENOG4105CPC	Aldo Keto reductase
HTY51_11975	ENOG4105CD8	aminopeptidase N
HTY51_11980	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HTY51_12020	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HTY51_12025	ENOG4105C28	cystathionine
HTY51_12030	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HTY51_12045	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HTY51_12050	ENOG4105KUZ	arsenate reductase
HTY51_12055	ENOG4105NBK	UPF0345 protein
HTY51_12060	ENOG4105CDH	Citrulline--aspartate ligase
HTY51_12085	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HTY51_12090	ENOG4108YXG	UPF0502 protein
HTY51_12095	ENOG4105CC9	acyl-Coa dehydrogenase
HTY51_12105	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HTY51_12110	ENOG4105BZU	Histidine kinase
HTY51_12115	ENOG4105BZU	Histidine kinase
HTY51_12125	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HTY51_12145	ENOG4105C7H	Helicase, RecD TraA family
HTY51_12165	ENOG4105DTN	riboflavin biosynthesis protein ribF
HTY51_12170	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HTY51_12175	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HTY51_12180	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HTY51_12185	ENOG4105I03	Flagellin
HTY51_12190	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HTY51_12195	ENOG4108IPJ	Membrane
HTY51_12200	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
HTY51_12205	ENOG4105CHR	reductase
HTY51_12235	ENOG4107QHF	type ii secretion system protein e
HTY51_12250	ENOG4105EYA	deoxyribonuclease
HTY51_12255	ENOG4105C0H	protease
HTY51_12260	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HTY51_12270	ENOG4107QVM	von Willebrand factor, type A
HTY51_12285	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HTY51_12290	ENOG4105D60	lipoprotein releasing system transmembrane protein
HTY51_12300	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HTY51_12305	ENOG4105BZU	Histidine kinase
HTY51_12310	ENOG4105DB7	PHP domain protein
HTY51_12320	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HTY51_12325	ENOG4108Z4T	Peptidase M50
HTY51_12330	ENOG4105C31	Tryptophanyl-tRNA synthetase
HTY51_12335	ENOG4108W3Q	Transcriptional regulator
HTY51_12370	ENOG4105DUM	transcriptional regulator, lysR family
HTY51_12380	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
HTY51_12410	ENOG4105CEY	Amp-dependent synthetase and ligase
HTY51_12420	ENOG4108W6C	Dehydrogenase
HTY51_12430	ENOG4105DHQ	Histidine kinase
HTY51_12435	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HTY51_12445	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HTY51_12450	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HTY51_12455	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HTY51_12460	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
HTY51_12465	ENOG4105W5Q	DNA repair protein (RadC
HTY51_12470	ENOG4105C98	muts2 protein
HTY51_12480	ENOG4105CV6	ABC transporter, permease
HTY51_12485	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HTY51_12505	ENOG4105QAX	Iron-sulfur
HTY51_12510	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HTY51_12520	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HTY51_12555	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HTY51_12565	ENOG4105C5Q	Transcriptional regulator
HTY51_12580	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HTY51_12605	ENOG4105CHH	sulfate transporter
HTY51_12620	ENOG4108IYU	L-aspartate oxidase
HTY51_12625	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HTY51_12630	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HTY51_12635	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HTY51_12640	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HTY51_12650	ENOG4105DCF	alanine dehydrogenase
HTY51_12655	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
HTY51_12675	ENOG4106H78	methyltransferase
HTY51_12695	ENOG4105BZU	Histidine kinase
HTY51_12720	ENOG41067HS	methyltransferase
HTY51_12740	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HTY51_12765	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
HTY51_12775	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HTY51_12780	ENOG4105CC0	LysR family Transcriptional regulator
HTY51_12785	ENOG4106KED	esterase YpfH
HTY51_12790	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HTY51_12800	ENOG4107RZC	phospholipase d
HTY51_12805	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
HTY51_12825	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HTY51_12830	ENOG4105BZU	Histidine kinase
HTY51_12850	ENOG4105CHP	RNA polymerase
HTY51_12865	ENOG4105GRZ	Ycii-related protein
HTY51_12870	ENOG4105GRZ	Ycii-related protein
HTY51_12880	ENOG4108V3W	Chemotaxis protein, CheW
HTY51_12890	ENOG4105C8Q	Methyl-accepting chemotaxis
HTY51_12900	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HTY51_12905	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HTY51_12910	ENOG4105BZU	Histidine kinase
HTY51_12915	ENOG4108IV0	ABC, transporter
HTY51_12920	ENOG4105C0Z	ABC transporter
HTY51_12925	ENOG4105CNN	ABC, transporter
HTY51_12930	ENOG4105C32	Amino acid ABC transporter (Permease)
HTY51_12935	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
HTY51_12940	ENOG4105CSR	polyphosphate kinase 2
HTY51_12965	ENOG4108V0P	LemA family
HTY51_12970	ENOG4105HA9	of methanol dehydrogenase type
HTY51_13010	ENOG4108JQ9	ABC transporter
HTY51_13025	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HTY51_13035	ENOG4108IJ6	ABC transporter
HTY51_13040	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HTY51_13070	ENOG4105FYV	Amp nucleosidase
HTY51_13090	ENOG4105NAE	bifunctional deaminase-reductase domain protein
HTY51_13095	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HTY51_13100	ENOG4105BZU	Histidine kinase
HTY51_13110	ENOG4105NAE	bifunctional deaminase-reductase domain protein
HTY51_13135	ENOG4105BZU	Histidine kinase
HTY51_13140	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
HTY51_13145	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HTY51_13155	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HTY51_13160	ENOG4108IV0	ABC, transporter
HTY51_13175	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
HTY51_13190	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HTY51_13205	ENOG4105KI2	Urea amidohydrolase subunit beta
HTY51_13210	ENOG4105CQM	Urea amidohydrolase subunit alpha
HTY51_13215	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
HTY51_13220	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HTY51_13225	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
HTY51_13250	ENOG4105EEF	Alkane 1-monooxygenase
HTY51_13260	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HTY51_13275	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HTY51_13285	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HTY51_13290	ENOG4105C37	(CBS) domain
HTY51_13295	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
HTY51_13300	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HTY51_13305	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HTY51_13310	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HTY51_13315	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HTY51_13320	ENOG4105K46	50S ribosomal protein l27
HTY51_13325	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HTY51_13330	ENOG4105EAH	synthase
HTY51_13340	ENOG4107QHF	type ii secretion system protein e
HTY51_13355	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HTY51_13360	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
HTY51_13365	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
HTY51_13370	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HTY51_13380	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HTY51_13385	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HTY51_13405	ENOG4105KB2	stringent starvation protein b
HTY51_13410	ENOG4107MKT	Stringent starvation protein a
HTY51_13415	ENOG4105EIX	cytochrome c1
HTY51_13420	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HTY51_13425	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HTY51_13430	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HTY51_13435	ENOG4107QNR	UPF0135 protein
HTY51_13445	ENOG4105C0H	protease
HTY51_13450	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HTY51_13455	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HTY51_13460	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HTY51_13465	ENOG4107YU2	histidine triad (hIT) protein
HTY51_13470	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
HTY51_13475	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HTY51_13480	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HTY51_13490	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HTY51_13500	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HTY51_13505	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HTY51_13515	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HTY51_13520	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HTY51_13525	ENOG4105VFK	BolA family
HTY51_13530	ENOG4105E3A	(ABC) transporter
HTY51_13535	ENOG4105DA5	(ABC) transporter
HTY51_13555	ENOG4107PE3	Mammalian cell entry related domain protein
HTY51_13560	ENOG4105CY3	ABC transporter, permease
HTY51_13565	ENOG4105DHJ	ABC, transporter
HTY51_13605	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HTY51_13610	ENOG4105D49	3-dehydroquinate synthase
HTY51_13615	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HTY51_13620	ENOG4105E4G	Type IV pilus
HTY51_13645	ENOG4108JQC	penicillin-binding protein 1A
HTY51_13650	ENOG4105XQ6	frataxin-like protein
HTY51_13660	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HTY51_13670	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
HTY51_13675	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HTY51_13680	ENOG4105CRE	cytochrome C
HTY51_13685	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
HTY51_13695	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HTY51_13715	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HTY51_13745	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HTY51_13750	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HTY51_13755	ENOG4107QP8	phosphohexose isomerase
HTY51_13760	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HTY51_13775	ENOG4108Z9W	Outer membrane porin
HTY51_13785	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
HTY51_13795	ENOG4105C7B	Threonine dehydratase
HTY51_13800	ENOG4105E39	Enoyl-CoA hydratase
HTY51_13825	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HTY51_13830	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HTY51_13835	ENOG4105CRE	cytochrome C
HTY51_13845	ENOG4107TUY	Histidine kinase
HTY51_13850	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HTY51_13860	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HTY51_13865	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HTY51_13875	ENOG4105VZ9	UPF0235 protein
HTY51_13880	ENOG4107T4Z	adenosine kinase
HTY51_13890	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HTY51_13895	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HTY51_13900	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HTY51_13905	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HTY51_13915	ENOG4105DFU	Cell wall formation (By similarity)
HTY51_13920	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HTY51_13925	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HTY51_13930	ENOG4105ZXK	Dehydrogenase
HTY51_13935	ENOG4105CNI	cell division protein FtsW
HTY51_13950	ENOG4105IPS	esterase
HTY51_13955	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
HTY51_13965	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HTY51_13970	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HTY51_13990	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HTY51_13995	ENOG4105BZU	Histidine kinase
HTY51_14010	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HTY51_14015	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HTY51_14020	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HTY51_14025	ENOG4105CPF	Cell wall formation (By similarity)
HTY51_14030	ENOG4105DFU	Cell wall formation (By similarity)
HTY51_14035	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HTY51_14040	ENOG4105CNI	cell division protein FtsW
HTY51_14045	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HTY51_14050	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HTY51_14055	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HTY51_14060	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HTY51_14065	ENOG4105CJN	penicillin-binding protein
HTY51_14075	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HTY51_14080	ENOG4108V6E	Cell division protein mraZ
HTY51_14085	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HTY51_14090	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HTY51_14105	ENOG4105CKI	cobalamin synthesis protein
HTY51_14110	ENOG4105DR4	Methyltransferase
HTY51_14115	ENOG4105C8Q	Methyl-accepting chemotaxis
HTY51_14120	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HTY51_14130	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HTY51_14155	ENOG4108M3P	Membrane
HTY51_14165	ENOG41063Z6	transcriptional regulator, lysR family
HTY51_14170	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HTY51_14180	ENOG4105DZ0	fad dependent oxidoreductase
HTY51_14190	ENOG4105BZU	Histidine kinase
HTY51_14195	ENOG4105D0M	Protease HtpX homolog
HTY51_14205	ENOG4105EKE	dihydroorotase
HTY51_14210	ENOG4105CDA	abc transporter atp-binding protein
HTY51_14215	ENOG4105DRP	amino acid AbC transporter
HTY51_14220	ENOG4105EAD	ABC transporter
HTY51_14225	ENOG4107RP9	extracellular solute-binding protein, family 3
HTY51_14235	ENOG4108JJ7	ABC transporter
HTY51_14240	ENOG4105NAU	thioesterase Superfamily protein
HTY51_14245	ENOG4108VUY	thioesterase Superfamily protein
HTY51_14265	ENOG4105CHU	acetyl-coa acetyltransferase
HTY51_14280	ENOG4105CSU	acyl-Coa dehydrogenase
HTY51_14300	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HTY51_14305	ENOG4105CAS	nag kinase
HTY51_14320	ENOG4105D3Q	Sugar transferase
HTY51_14340	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HTY51_14345	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HTY51_14385	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HTY51_14400	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HTY51_14410	ENOG4105F0R	Cytidylyltransferase
HTY51_14420	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
HTY51_14425	ENOG4105D2T	synthase
HTY51_14435	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HTY51_14440	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HTY51_14445	ENOG4105BZ1	(ABC) transporter
HTY51_14450	ENOG4105F2I	Transposase
HTY51_14455	ENOG4105C30	Nad-dependent epimerase dehydratase
HTY51_14470	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HTY51_14480	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HTY51_14510	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HTY51_14535	ENOG4108IV0	ABC, transporter
HTY51_14550	ENOG4105C32	Amino acid ABC transporter (Permease)
HTY51_14555	ENOG4105C0Z	ABC transporter
HTY51_14565	ENOG4105IJJ	transcriptional regulator, crp fnr family
HTY51_14570	ENOG4105CHB	tonB-dependent Receptor
HTY51_14575	ENOG4106RE7	Cytochrome
HTY51_14580	ENOG4105DKB	L-sorbosone dehydrogenase
HTY51_14585	ENOG4105DKB	L-sorbosone dehydrogenase
HTY51_14595	ENOG4105FE9	pseudouridine synthase
HTY51_14600	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HTY51_14635	ENOG4105E27	serine threonine protein kinase
HTY51_14640	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HTY51_14645	ENOG4105D9P	serine threonine protein kinase
HTY51_14675	ENOG4105D5P	Methylmalonyl-coA mutase
HTY51_14680	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HTY51_14690	ENOG4105CH5	extracellular solute-binding protein, family 7
HTY51_14695	ENOG4105ERH	Fumarylacetoacetate hydrolase
HTY51_14700	ENOG4107QPB	Beta-lactamase domain protein
HTY51_14705	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HTY51_14710	ENOG4105CH2	amidohydrolase
HTY51_14725	ENOG4108ZT0	50S ribosomal protein l17
HTY51_14730	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HTY51_14735	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HTY51_14740	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HTY51_14745	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HTY51_14750	ENOG41067V7	50S ribosomal protein L36
HTY51_14760	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HTY51_14765	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HTY51_14770	ENOG4105VPB	50S ribosomal protein L30
HTY51_14775	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HTY51_14780	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HTY51_14785	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HTY51_14790	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HTY51_14795	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HTY51_14800	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HTY51_14805	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HTY51_14810	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HTY51_14815	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HTY51_14825	ENOG4105II7	pyrroline-5-carboxylate reductase
HTY51_14830	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HTY51_14840	ENOG4105C5Q	Transcriptional regulator
HTY51_14855	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
HTY51_14860	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HTY51_14870	ENOG4105CB5	ATP-dependent DNA helicase recG
HTY51_14875	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HTY51_14885	ENOG4105C4W	S-formylglutathione hydrolase
HTY51_14900	ENOG4108S8N	class II Aldolase
HTY51_14905	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HTY51_14910	ENOG4108WQI	RNA Polymerase
HTY51_14925	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HTY51_14930	ENOG4105BZU	Histidine kinase
HTY51_14935	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HTY51_14940	ENOG4108MAJ	Membrane
HTY51_14970	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
HTY51_14975	ENOG4105D5T	phosphonate abc transporter
HTY51_14980	ENOG4105FD8	phosphonate metabolism protein PhnM
HTY51_14985	ENOG4105HRV	phosphonate c-p lyase system protein phnl
HTY51_14990	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
HTY51_15000	ENOG4105FT8	Phosphonate metabolism
HTY51_15015	ENOG4105KQZ	Phosphonate C-P lyase system protein PhnG
HTY51_15025	ENOG4105MFQ	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity)
HTY51_15030	ENOG4108TXN	phosphonate metabolism protein
HTY51_15045	ENOG4105CEY	Amp-dependent synthetase and ligase
HTY51_15060	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
HTY51_15085	ENOG4105BZU	Histidine kinase
HTY51_15090	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HTY51_15095	ENOG4105ERH	Fumarylacetoacetate hydrolase
HTY51_15150	ENOG4105CMJ	mandelate racemase muconate lactonizing
HTY51_15155	ENOG4107YNJ	LysR family Transcriptional regulator
HTY51_15190	ENOG4105VF7	tolerance protein
HTY51_15205	ENOG4105DJ4	phosphatidylserine decarboxylase
HTY51_15210	ENOG4105CQB	FAD linked oxidase domain protein
HTY51_15215	ENOG4105VAW	lrga family
HTY51_15220	ENOG41067MG	lrgb family
HTY51_15225	ENOG4105BZU	Histidine kinase
HTY51_15235	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HTY51_15240	ENOG4105C8Q	Methyl-accepting chemotaxis
HTY51_15245	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
HTY51_15270	ENOG41066UZ	arginase EC 3.5.3.1
HTY51_15275	ENOG4105BZU	Histidine kinase
HTY51_15280	ENOG4106855	Competence protein
HTY51_15290	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HTY51_15305	ENOG4105DFA	alanine racemase domain protein
HTY51_15310	ENOG4105CZX	twitching motility protein
HTY51_15315	ENOG4105CZX	twitching motility protein
HTY51_15320	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HTY51_15330	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HTY51_15335	ENOG41082RQ	UPF0102 protein
HTY51_15340	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HTY51_15350	ENOG4105D82	Glutamate dehydrogenase
HTY51_15355	ENOG4105C26	Dehydrogenase
HTY51_15370	ENOG4105MPD	Cytochrome
HTY51_15380	ENOG4105CEY	Amp-dependent synthetase and ligase
HTY51_15400	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HTY51_15405	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HTY51_15410	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HTY51_15415	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HTY51_15420	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HTY51_15425	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HTY51_15430	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HTY51_15435	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
HTY51_15450	ENOG4105F0I	Aminotransferase
HTY51_15455	ENOG4108Z43	UPF0250 protein
HTY51_15460	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HTY51_15465	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HTY51_15475	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HTY51_15480	ENOG41080Z8	PHOSPHOCARRIER protein
HTY51_15505	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HTY51_15520	ENOG4108K0D	peptidase, M48
HTY51_15535	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HTY51_15540	ENOG41084PQ	50s ribosomal protein l29
HTY51_15545	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HTY51_15550	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HTY51_15555	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HTY51_15560	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HTY51_15565	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HTY51_15570	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HTY51_15575	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HTY51_15580	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HTY51_15585	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HTY51_15595	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HTY51_15600	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HTY51_15605	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HTY51_15610	ENOG4105DZ1	carboxypeptidase
HTY51_15615	ENOG4105DHZ	alpha beta
HTY51_15630	ENOG4108YXA	Membrane
HTY51_15635	ENOG4105D52	delta-aminolevulinic acid dehydratase
HTY51_15640	ENOG4105D7N	magnesium and cobalt transport protein CorA
HTY51_15665	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HTY51_15670	ENOG4108ZMQ	domain protein
HTY51_15675	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HTY51_15680	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HTY51_15685	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HTY51_15695	ENOG4105CH5	extracellular solute-binding protein, family 7
HTY51_15720	ENOG4105E39	Enoyl-CoA hydratase
HTY51_15725	ENOG4107QPK	)-transporter
HTY51_15730	ENOG4105CN8	Transcriptional regulator
HTY51_15735	ENOG4105C26	Dehydrogenase
HTY51_15755	ENOG4105CJN	penicillin-binding protein
HTY51_15775	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HTY51_15780	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HTY51_15785	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HTY51_15795	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HTY51_15800	ENOG4105CGK	Exodeoxyribonuclease III
HTY51_15810	ENOG4105C5X	domain protein
HTY51_15825	ENOG4105EYM	Major Facilitator superfamily
HTY51_15835	ENOG4105E0F	Histidine kinase
HTY51_15845	ENOG4105XA0	heptosyltransferase ii
HTY51_15855	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HTY51_15865	ENOG4105CV8	reductase
HTY51_15875	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HTY51_15880	ENOG4108V8F	Transcriptional regulator, MarR family
HTY51_15895	ENOG4105C26	Dehydrogenase
HTY51_15900	ENOG4107THI	3,4-dihydroxyphenylacetate 2,3-dioxygenase
HTY51_15920	ENOG4105MP9	class II Aldolase
HTY51_15925	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HTY51_15945	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HTY51_15960	ENOG4108V06	Glutathione peroxidase
HTY51_15965	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HTY51_15970	ENOG4105EU8	FAD linked oxidase domain protein
HTY51_15975	ENOG4105BZU	Histidine kinase
HTY51_15980	ENOG4108YZA	Nitrogen regulatory protein pii
HTY51_15990	ENOG4105C0P	Mg chelatase subunit ChlI
HTY51_16010	ENOG4105C3R	Methionine synthase
HTY51_16020	ENOG4105EVD	ribosomal RNA large subunit methyltransferase N
HTY51_16025	ENOG4105DU1	integral membrane protein, terc
HTY51_16030	ENOG4105C3R	Methionine synthase
HTY51_16040	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HTY51_16060	ENOG4105E0C	molybdate abc transporter
HTY51_16065	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HTY51_16070	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
HTY51_16095	ENOG4105KXI	murein peptide amidase A
HTY51_16110	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HTY51_16120	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HTY51_16125	ENOG4105C1G	acyl-Coa dehydrogenase
HTY51_16130	ENOG4105ETT	transcriptional Regulator, LysR family
HTY51_16135	ENOG4105BZU	Histidine kinase
HTY51_16140	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HTY51_16155	ENOG4105BZU	Histidine kinase
HTY51_16170	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HTY51_16175	ENOG4105C2W	permease
HTY51_16185	ENOG4108WBT	adenosyltransferase
HTY51_16190	ENOG4105CQB	FAD linked oxidase domain protein
HTY51_16195	ENOG4105BZU	Histidine kinase
HTY51_16200	ENOG4105UYK	outer membrane protein a
HTY51_16230	ENOG4105FA0	parb-like partition protein
HTY51_16240	ENOG4107QJE	Chromosome Partitioning Protein
HTY51_16250	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HTY51_16255	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HTY51_16270	ENOG4108IV0	ABC, transporter
HTY51_16275	ENOG4105C0Z	ABC transporter
HTY51_16285	ENOG4105C32	Amino acid ABC transporter (Permease)
HTY51_16300	ENOG4105MP9	class II Aldolase
HTY51_16310	ENOG4105MPD	Cytochrome
HTY51_16320	ENOG4105C8Q	Methyl-accepting chemotaxis
HTY51_16325	ENOG4105C59	p-type ATPase
HTY51_16345	ENOG4105BZU	Histidine kinase
HTY51_16350	ENOG4105EUB	pirin domain protein
HTY51_16380	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HTY51_16390	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HTY51_16395	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HTY51_16400	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HTY51_16405	ENOG4105VG0	50S ribosomal protein l34
HTY51_16410	ENOG4105X5M	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HTY51_16415	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HTY51_16420	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HTY51_16425	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HTY51_16435	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HTY51_16445	ENOG4105C2X	Arabinose 5-phosphate isomerase
HTY51_16450	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
HTY51_16460	ENOG4107FW0	short-chain dehydrogenase reductase
HTY51_16465	ENOG4105VFU	Rna-binding protein
HTY51_16485	ENOG4105E18	UPF0276 protein
HTY51_16505	ENOG4105W1Y	Transcriptional regulator
HTY51_16510	ENOG4105KK4	UPF0060 membrane protein
HTY51_16520	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HTY51_16585	ENOG4105GR3	Histidine kinase
HTY51_16635	ENOG4105C59	p-type ATPase
HTY51_16645	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
HTY51_16650	ENOG4108IJF	Heavy metal efflux pump, CzcA
HTY51_16695	ENOG4108VVQ	metallophosphoesterase
HTY51_16705	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HTY51_16750	ENOG4105TMB	Formate nitrite transporter
HTY51_16755	ENOG4105DWV	Homoserine O-trans-acetylase
HTY51_16760	ENOG4105DWV	Homoserine O-trans-acetylase
HTY51_16765	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HTY51_16770	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HTY51_16780	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
HTY51_16790	ENOG4105E5G	Alpha beta hydrolase fold
HTY51_16795	ENOG4105DXI	Major Facilitator superfamily
HTY51_16800	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HTY51_16805	ENOG4105EHM	Aminoglycoside phosphotransferase
HTY51_16810	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HTY51_16815	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HTY51_16820	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HTY51_16840	ENOG4105C6K	Malic enzyme
HTY51_16890	ENOG4107RAQ	aminopeptidase
HTY51_16895	ENOG4108S0S	Nucleotidyl transferase
HTY51_16900	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HTY51_16905	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HTY51_16915	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HTY51_16925	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HTY51_16935	ENOG4105DHQ	Histidine kinase
HTY51_16950	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HTY51_16955	ENOG4108004	Modulates RecA activity (By similarity)
HTY51_16960	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HTY51_16965	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HTY51_16970	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HTY51_16975	ENOG4108ZCF	integral membrane protein
HTY51_16980	ENOG4108ZF3	Phosphatase
HTY51_16985	ENOG4108UW8	fha domain-containing protein
HTY51_16995	ENOG4107QHF	type ii secretion system protein e
HTY51_17005	ENOG4108YSG	O-Antigen polymerase
HTY51_17015	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HTY51_17020	ENOG4105YWY	
HTY51_17025	ENOG4105ERG	peptidase m48, ste24p
HTY51_17030	ENOG41086DT	Membrane protein of unknown function
HTY51_17035	ENOG4108ZCF	integral membrane protein
HTY51_17045	ENOG4108VWS	Yaeq family
HTY51_17050	ENOG4107QTF	adenylosuccinate lyase
HTY51_17055	ENOG4108U78	Glutathione S-transferase
HTY51_17070	ENOG4107Z67	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HTY51_17075	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HTY51_17090	ENOG4105BZU	Histidine kinase
HTY51_17095	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HTY51_17115	ENOG4108YXU	transcriptional regulator AsnC family
HTY51_17125	ENOG4105VIE	preprotein translocase, subunit YajC
HTY51_17130	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HTY51_17135	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HTY51_17145	ENOG4108RPN	Protein smg homolog
HTY51_17150	ENOG4105C79	DNA protecting protein DprA
HTY51_17160	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HTY51_17165	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HTY51_17180	ENOG4105BZA	Phosphoglycerate kinase
HTY51_17185	ENOG4105CA9	Pyruvate kinase
HTY51_17190	ENOG4105D2N	Aldolase
HTY51_17195	ENOG4105C8V	SAICAR synthetase
HTY51_17200	ENOG4107QR8	Thioredoxin
HTY51_17205	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HTY51_17210	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HTY51_17215	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HTY51_17220	ENOG4105W3H	MtN3 and saliva related transmembrane protein
HTY51_17225	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
HTY51_17235	ENOG41072GX	Peptidase M22 Glycoprotease
HTY51_17245	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
HTY51_17255	ENOG4108784	2'-5' rna ligase
HTY51_17275	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
HTY51_17290	ENOG4107RDB	Major Facilitator
HTY51_17300	ENOG4105C26	Dehydrogenase
HTY51_17310	ENOG4105CXK	mandelate racemase muconate lactonizing
HTY51_17315	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HTY51_17350	ENOG4105VPX	protein, conserved in bacteria
HTY51_17355	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HTY51_17370	ENOG4105UIB	(ABC) transporter
HTY51_17375	ENOG4108JQ9	ABC transporter
HTY51_17380	ENOG4108HR6	Dehydrogenase
HTY51_17385	ENOG4105C7W	Xanthine dehydrogenase
HTY51_17390	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HTY51_17415	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HTY51_17440	ENOG4108IV0	ABC, transporter
HTY51_17460	ENOG4105CHR	reductase
HTY51_17480	ENOG4107EFR	Flavocytochrome c
HTY51_17485	ENOG4105CHR	reductase
HTY51_17490	ENOG4107EFR	Flavocytochrome c
HTY51_17495	ENOG41079YP	Citrate utilization protein b
HTY51_17520	ENOG4105C5I	Dehydrogenase
HTY51_17530	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HTY51_17535	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HTY51_17540	ENOG4105CEY	Amp-dependent synthetase and ligase
HTY51_17550	ENOG4107QUT	magnesium and cobalt transport protein CorA
HTY51_17555	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
HTY51_17560	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HTY51_17565	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
HTY51_17570	ENOG41090R7	Ferric uptake
HTY51_17575	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HTY51_17585	ENOG4105C8T	Leucyl-tRNA synthetase
HTY51_17600	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HTY51_17615	ENOG4105DFH	Transport of potassium into the cell (By similarity)
HTY51_17620	ENOG4108Z33	Thiol disulfide Interchange Protein
HTY51_17630	ENOG4105C75	arginyL-tRNA synthetase
HTY51_17640	ENOG4105JQN	Transcriptional regulator
HTY51_17650	ENOG4108M9J	MaoC like domain protein
HTY51_17655	ENOG4105C1G	acyl-Coa dehydrogenase
HTY51_17695	ENOG4107QP3	malate synthase g
HTY51_17700	ENOG4105CB2	alcohol dehydrogenase
HTY51_17705	ENOG4105E1F	short-chain dehydrogenase reductase
HTY51_17710	ENOG4108IG5	Transcriptional regulator
HTY51_17715	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HTY51_17780	ENOG4105CKI	cobalamin synthesis protein
HTY51_17785	ENOG4107HP6	Transcriptional regulator
HTY51_17790	ENOG4105CPQ	Dehydrogenase
HTY51_17805	ENOG4107BVJ	4,5-dihydroxyphthalate decarboxylase
HTY51_17835	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HTY51_17840	ENOG4105E7A	Glutamine amidotransferase
HTY51_17845	ENOG4105C8Q	Methyl-accepting chemotaxis
HTY51_17850	ENOG4105D7Z	glutathione synthase
HTY51_17855	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
HTY51_17860	ENOG4108IUZ	ABC transporter
HTY51_17865	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HTY51_17870	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HTY51_17880	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HTY51_17885	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
HTY51_17910	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HTY51_17920	ENOG4105NWN	ApaG protein
HTY51_17925	ENOG4105DJV	ribulose-phosphate 3-epimerase
HTY51_17930	ENOG4105BZU	Histidine kinase
HTY51_17945	ENOG4105DDQ	anthranilate synthase
HTY51_17950	ENOG4107QYG	anthranilate phosphoribosyltransferase
HTY51_17955	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HTY51_18000	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HTY51_18005	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HTY51_18010	ENOG4108VZM	50s ribosomal protein L10
HTY51_18015	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HTY51_18020	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HTY51_18025	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HTY51_18030	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HTY51_18040	ENOG4105ES5	Histidine kinase
HTY51_18065	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
HTY51_18070	ENOG4105HDD	phospholipase
HTY51_18075	ENOG4105C4R	Atp-dependent dna helicase
HTY51_18085	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
HTY51_18090	ENOG4105C5Q	Transcriptional regulator
HTY51_18095	ENOG4105C25	Primosomal protein n'
HTY51_18100	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HTY51_18110	ENOG4105K4P	CoA-binding domain protein
HTY51_18115	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HTY51_18120	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HTY51_18130	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HTY51_18145	ENOG4105BZU	Histidine kinase
HTY51_18170	ENOG4105ETT	transcriptional Regulator, LysR family
HTY51_18180	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HTY51_18185	ENOG4105NI3	Protein of unknown function (DUF3237)
HTY51_18205	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HTY51_18210	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HTY51_18215	ENOG4105T38	integral membrane protein
HTY51_18230	ENOG4105E1Q	flagellar hook-associated protein
HTY51_18235	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HTY51_18240	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HTY51_18250	ENOG4105CGA	flagellar basal-body rod protein FlgG
HTY51_18255	ENOG4108KPB	Flagellar basal-body rod protein FlgF
HTY51_18260	ENOG4105BZE	flagellar hook protein, FlgE
HTY51_18265	ENOG4105W00	Flagellar hook capping protein
HTY51_18270	ENOG4108ZC9	flagellar basal-body rod protein flgc
HTY51_18275	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HTY51_18305	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HTY51_18310	ENOG4105FZW	flagellar biosynthesis regulator FlhF
HTY51_18315	ENOG4105D7B	Flagellar biosynthesis protein flha
HTY51_18320	ENOG4105D00	flagellar biosynthetic protein flhB
HTY51_18325	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
HTY51_18330	ENOG4108VYJ	response regulator receiver protein
HTY51_18335	ENOG4105ER2	Ompa motb domain protein
HTY51_18340	ENOG4107RD7	Flagellar Motor Protein, MotA
HTY51_18345	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
HTY51_18350	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
HTY51_18355	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
HTY51_18360	ENOG4105FAW	cDP-glucose 4,6-dehydratase
HTY51_18395	ENOG4105I03	Flagellin
HTY51_18415	ENOG4105DTS	flagellar hook-associated
HTY51_18420	ENOG4105MQ3	flagellar protein FliS
HTY51_18430	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
HTY51_18435	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HTY51_18440	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HTY51_18450	ENOG4108JIR	Flagellum-specific ATP synthase
HTY51_18470	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HTY51_18475	ENOG4105DD5	Flagellar motor switch protein