locus-tag	class	description
NOVO_00050	ENOG4107YUR	Cell division protein mraZ
NOVO_00160	ENOG4105BZN	citrate synthase
NOVO_00200	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
NOVO_00210	ENOG4108ZAI	phosphatidylglycerophosphatase a
NOVO_00220	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
NOVO_00260	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
NOVO_00270	ENOG4105D3R	alkyl hydroperoxide reductase
NOVO_00275	ENOG4105C3M	thioredoxin reductase
NOVO_00350	ENOG4105D78	K07001 NTE family protein
NOVO_00455	ENOG41082AG	Plasmid maintenance system antidote protein
NOVO_00495	ENOG4105C57	major facilitator superfamily
NOVO_00515	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
NOVO_00520	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
NOVO_00575	ENOG4108V9Q	carbonic anhydrase
NOVO_00610	ENOG4107V1F	Flagellar hook-associated 2 domain-containing protein
NOVO_00615	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
NOVO_00630	ENOG4105C9M	aspartyl-trna synthetase
NOVO_00645	ENOG4106S8I	
NOVO_00650	ENOG4105DWF	phosphomethylpyrimidine kinase
NOVO_00655	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
NOVO_00665	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
NOVO_00675	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
NOVO_00705	ENOG4105CBX	hi0933 family
NOVO_00730	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
NOVO_00735	ENOG4105W49	UPF0434 protein
NOVO_00740	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
NOVO_00745	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
NOVO_00750	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
NOVO_00755	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
NOVO_00760	ENOG4108MAJ	Membrane
NOVO_00780	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
NOVO_00805	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
NOVO_00810	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
NOVO_00815	ENOG4108V1U	phospholipid-binding protein
NOVO_00830	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
NOVO_00875	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
NOVO_00880	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
NOVO_00890	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
NOVO_00895	ENOG4105DQR	SNARE associated Golgi
NOVO_00900	ENOG4105C7Z	Conserved Protein
NOVO_00935	ENOG4105HFZ	Membrane
NOVO_00945	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
NOVO_00955	ENOG4105BZU	Histidine kinase
NOVO_00990	ENOG4105BZU	Histidine kinase
NOVO_01015	ENOG4105D7B	Flagellar biosynthesis protein flha
NOVO_01020	ENOG4105E9Q	Acyl-transferase
NOVO_01025	ENOG4105NWN	ApaG protein
NOVO_01045	ENOG4105DX0	Hemolysin A
NOVO_01070	ENOG4105C79	DNA protecting protein DprA
NOVO_01085	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
NOVO_01090	ENOG4105CIH	Imidazole acetol-phosphate transaminase
NOVO_01195	ENOG4105K63	Thioredoxin
NOVO_01260	ENOG4107QM5	aconitate hydratase
NOVO_01285	ENOG41068WN	
NOVO_01340	ENOG4107ZGG	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
NOVO_01345	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
NOVO_01355	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
NOVO_01360	ENOG4105C75	arginyL-tRNA synthetase
NOVO_01405	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
NOVO_01410	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
NOVO_01420	ENOG4105C02	permease
NOVO_01430	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
NOVO_01465	ENOG4105CGA	flagellar basal-body rod protein FlgG
NOVO_01480	ENOG4106909	Flagellar assembly regulator FliX
NOVO_01485	ENOG4105DFI	Membrane
NOVO_01505	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
NOVO_01510	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
NOVO_01520	ENOG4105EIX	cytochrome c1
NOVO_01525	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
NOVO_01540	ENOG4105BZU	Histidine kinase
NOVO_01545	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
NOVO_01550	ENOG4105FAV	ABC, transporter
NOVO_01575	ENOG4105DFA	alanine racemase domain protein
NOVO_01585	ENOG4106H78	methyltransferase
NOVO_01590	ENOG4105FE9	pseudouridine synthase
NOVO_01595	ENOG4108Z86	Glutamine amidotransferase
NOVO_01600	ENOG4105CSH	Transporter
NOVO_01605	ENOG4105CGK	Exodeoxyribonuclease III
NOVO_01610	ENOG4107QX8	SPFH domain, Band 7 family protein
NOVO_01635	ENOG4108RW8	Universal stress protein F
NOVO_01640	ENOG4105CTB	Polyprenyl synthetase
NOVO_01645	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
NOVO_01650	ENOG4105CAY	ferredoxin--nadp reductase
NOVO_01655	ENOG4105CNI	cell division protein FtsW
NOVO_01800	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
NOVO_01815	ENOG4108V0P	LemA family
NOVO_01820	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
NOVO_01825	ENOG4105CAT	Cytidine monophosphate kinase
NOVO_01830	ENOG4108ZNX	Heat shock protein
NOVO_01840	ENOG4105C26	Dehydrogenase
NOVO_01850	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
NOVO_01870	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
NOVO_01885	ENOG4105CXT	aspartate transcarbamylase
NOVO_01910	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
NOVO_01925	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
NOVO_01935	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
NOVO_01945	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
NOVO_01950	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
NOVO_02090	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
NOVO_02105	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
NOVO_02150	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
NOVO_02155	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
NOVO_02165	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
NOVO_02170	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
NOVO_02185	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NOVO_02190	ENOG4105DZP	Membrane-associated zinc metalloprotease
NOVO_02195	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
NOVO_02210	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
NOVO_02215	ENOG4108JPZ	Monovalent cation H antiporter subunit D
NOVO_02240	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
NOVO_02245	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
NOVO_02250	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
NOVO_02255	ENOG4105C03	ribonuclease
NOVO_02275	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
NOVO_02285	ENOG4105CP7	Triose-phosphate isomerase
NOVO_02290	ENOG4108S1R	peptidylprolyl cis-trans isomerase
NOVO_02300	ENOG4105C1J	atp-dependent rna helicase
NOVO_02310	ENOG4105W00	Flagellar hook capping protein
NOVO_02325	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
NOVO_02330	ENOG4107R25	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
NOVO_02335	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
NOVO_02345	ENOG4105EJX	conjugal transfer ATPase
NOVO_02375	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
NOVO_02395	ENOG4107QPK	)-transporter
NOVO_02400	ENOG4108RG0	uracil-dna glycosylase
NOVO_02410	ENOG4105CBT	Fructose-1,6-bisphosphatase
NOVO_02420	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
NOVO_02425	ENOG4108WRK	Transcriptional regulator
NOVO_02430	ENOG4105C3G	gtp-binding protein
NOVO_02440	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
NOVO_02450	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
NOVO_02455	ENOG4105C3F	Signal peptidase i
NOVO_02460	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
NOVO_02465	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
NOVO_02490	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
NOVO_02500	ENOG4105ECY	inositol monophosphatase
NOVO_02505	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
NOVO_02510	ENOG4105EIE	fructose-bisphosphate aldolase
NOVO_02530	ENOG4105C72	UPF0176 protein
NOVO_02545	ENOG4108ZC9	flagellar basal-body rod protein flgc
NOVO_02555	ENOG4105VS8	Flagellar biosynthetic protein fliq
NOVO_02575	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
NOVO_02580	ENOG41082BR	50S ribosomal protein L35
NOVO_02590	ENOG4105CUG	Oligopeptidase b
NOVO_02600	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
NOVO_02605	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
NOVO_02640	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
NOVO_02645	ENOG4108VZM	50s ribosomal protein L10
NOVO_02650	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
NOVO_02655	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
NOVO_02660	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
NOVO_02675	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
NOVO_02680	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
NOVO_02685	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
NOVO_02690	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
NOVO_02700	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
NOVO_02705	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
NOVO_02715	ENOG4105E0F	Histidine kinase
NOVO_02720	ENOG4105DFI	Membrane
NOVO_02725	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
NOVO_02730	ENOG41090R7	Ferric uptake
NOVO_02740	ENOG4105CEV	competence damage-inducible protein
NOVO_02745	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
NOVO_02750	ENOG4105W5Q	DNA repair protein (RadC
NOVO_02765	ENOG4105CK2	sodium dicarboxylate symporter
NOVO_02770	ENOG4105CPF	Cell wall formation (By similarity)
NOVO_02775	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
NOVO_02780	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
NOVO_02790	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
NOVO_02805	ENOG4105CSA	Coproporphyrinogen iii oxidase
NOVO_02810	ENOG4107XZX	Involved in the transcription termination process (By similarity)
NOVO_02845	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
NOVO_02850	ENOG4105W0E	50S ribosomal protein L33
NOVO_02885	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
NOVO_02890	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
NOVO_02900	ENOG4107QYG	anthranilate phosphoribosyltransferase
NOVO_02905	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
NOVO_02915	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
NOVO_02920	ENOG41085Y2	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
NOVO_02925	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
NOVO_02940	ENOG4105K5G	30S ribosomal protein S21
NOVO_02950	ENOG4105DK7	lysyl-tRNA synthetase
NOVO_02960	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
NOVO_02965	ENOG4105KPY	Small multidrug resistance protein
NOVO_03030	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
NOVO_03035	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
NOVO_03040	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
NOVO_03050	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
NOVO_03060	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
NOVO_03065	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
NOVO_03075	ENOG4105VF7	tolerance protein
NOVO_03130	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
NOVO_03140	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
NOVO_03145	ENOG4105DTN	riboflavin biosynthesis protein ribF
NOVO_03155	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
NOVO_03160	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
NOVO_03165	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
NOVO_03170	ENOG4105CE9	30S ribosomal protein S2
NOVO_03175	ENOG4105CPF	Cell wall formation (By similarity)
NOVO_03185	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
NOVO_03235	ENOG4105CY3	ABC transporter, permease
NOVO_03240	ENOG4105DHJ	ABC, transporter
NOVO_03250	ENOG4105EUJ	GTP cyclohydrolase i
NOVO_03255	ENOG4108KAG	Cytochrome C oxidase, subunit I
NOVO_03265	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
NOVO_03275	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
NOVO_03280	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
NOVO_03305	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
NOVO_03315	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
NOVO_03330	ENOG4105CDA	abc transporter atp-binding protein
NOVO_03335	ENOG4105E5Q	amino acid AbC transporter
NOVO_03340	ENOG4108HW3	(ABC) transporter
NOVO_03345	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
NOVO_03360	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NOVO_03365	ENOG4107QJN	gtp cyclohydrolase ii
NOVO_03370	ENOG4105W4M	Transport-associated protein
NOVO_03375	ENOG4107U9T	Pfam:Ribonuclease_BN
NOVO_03385	ENOG4108EHY	type IV secretion system
NOVO_03390	ENOG4105CMA	conjugation trbi family protein
NOVO_03400	ENOG4108V42	Type IV secretion system protein VirB8
NOVO_03405	ENOG4107RCQ	(CBS) domain
NOVO_03410	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
NOVO_03415	ENOG4105C9A	Phoh family
NOVO_03435	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NOVO_03440	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
NOVO_03445	ENOG41086GJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
NOVO_03450	ENOG4105EGS	Mechanosensitive ion channel
NOVO_03475	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
NOVO_03480	ENOG4108I5D	sulfate abc transporter
NOVO_03490	ENOG4108IJ6	ABC transporter
NOVO_03505	ENOG4107QN2	dihydrolipoyl dehydrogenase
NOVO_03525	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
NOVO_03550	ENOG4108Z1B	Cyclase dehydrase
NOVO_03555	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
NOVO_03565	ENOG4107QRG	dna polymerase iii
NOVO_03590	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
NOVO_03595	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
NOVO_03605	ENOG4105K46	50S ribosomal protein l27
NOVO_03610	ENOG4105EEI	dihydropteroate synthase
NOVO_03615	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
NOVO_03620	ENOG4105HHA	aminodeoxychorismate lyase
NOVO_03625	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
NOVO_03630	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
NOVO_03645	ENOG4105BZ1	(ABC) transporter
NOVO_03655	ENOG4108JQC	penicillin-binding protein 1A
NOVO_03665	ENOG4105BZU	Histidine kinase
NOVO_03670	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NOVO_03675	ENOG4108JU6	CBS domain protein
NOVO_03680	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
NOVO_03730	ENOG4107QUT	magnesium and cobalt transport protein CorA
NOVO_03765	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
NOVO_03775	ENOG4105II7	pyrroline-5-carboxylate reductase
NOVO_03785	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
NOVO_03820	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
NOVO_03830	ENOG4105DC1	bifunctional purine biosynthesis protein purh
NOVO_03840	ENOG4108ZZF	transport protein (ExbD)
NOVO_03845	ENOG4105E02	MotA TolQ exbB proton channel
NOVO_03850	ENOG4108IUZ	ABC transporter
NOVO_03865	ENOG4105C2X	Arabinose 5-phosphate isomerase
NOVO_03885	ENOG4106ABQ	septum formation initiator
NOVO_03900	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
NOVO_03905	ENOG4108154	Acetyltransferase (GNAT) family
NOVO_03920	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
NOVO_03930	ENOG4105CN1	protease
NOVO_03935	ENOG4105BZU	Histidine kinase
NOVO_03955	ENOG4108JYK	Dehydrogenase
NOVO_03960	ENOG4105CUB	amino acid
NOVO_03965	ENOG4105CUB	amino acid
NOVO_03970	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
NOVO_03975	ENOG4105EAH	synthase
NOVO_04010	ENOG4107QJE	Chromosome Partitioning Protein
NOVO_04020	ENOG4105C8T	Leucyl-tRNA synthetase
NOVO_04030	ENOG4105CHM	Aminotransferase
NOVO_04040	ENOG4107ESN	Flagella basal body P-ring formation protein flgA
NOVO_04045	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
NOVO_04070	ENOG4105C5H	ABC transporter
NOVO_04080	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
NOVO_04090	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
NOVO_04100	ENOG4105EI2	Pseudouridine synthase
NOVO_04120	ENOG4107QPR	SAICAR synthetase
NOVO_04125	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
NOVO_04130	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
NOVO_04135	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
NOVO_04140	ENOG4107TYR	Glycosyl Transferase
NOVO_04150	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
NOVO_04155	ENOG4105C0P	Mg chelatase subunit ChlI
NOVO_04160	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
NOVO_04165	ENOG4108UJD	30S ribosomal protein S9
NOVO_04170	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
NOVO_04175	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
NOVO_04180	ENOG4105VFF	UPF0102 protein
NOVO_04210	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
NOVO_04230	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
NOVO_04245	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
NOVO_04250	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
NOVO_04255	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
NOVO_04260	ENOG4105CDY	transcriptional regulatory protein
NOVO_04265	ENOG4108Z03	MAF-like protein
NOVO_04270	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
NOVO_04275	ENOG4105U0R	haloacid dehalogenase-like hydrolase
NOVO_04285	ENOG4107QJE	Chromosome Partitioning Protein
NOVO_04290	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
NOVO_04295	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
NOVO_04300	ENOG4106WTF	Glycosyl transferase, family 2
NOVO_04305	ENOG4107T8Q	Glycosyl transferase (Group 1
NOVO_04320	ENOG41060IM	Heme exporter protein
NOVO_04325	ENOG4108Z4U	Ferredoxin
NOVO_04335	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
NOVO_04355	ENOG4105EEI	dihydropteroate synthase
NOVO_04365	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
NOVO_04370	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
NOVO_04375	ENOG41082R8	50S ribosomal protein l32
NOVO_04385	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
NOVO_04390	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
NOVO_04400	ENOG4105BZU	Histidine kinase
NOVO_04405	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
NOVO_04415	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
NOVO_04425	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
NOVO_04435	ENOG4105KCK	Peptidoglycan-associated lipoprotein
NOVO_04450	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
NOVO_04460	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
NOVO_04480	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
NOVO_04485	ENOG4108S0S	Nucleotidyl transferase
NOVO_04505	ENOG4108N3W	hemolysin secretion protein
NOVO_04520	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
NOVO_04540	ENOG4105VW4	glutaredoxin 3
NOVO_04545	ENOG4105DY9	regulatoR
NOVO_04560	ENOG4108JDX	DNA polymerase iii, epsilon subunit
NOVO_04565	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
NOVO_04570	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
NOVO_04575	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
NOVO_04580	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
NOVO_04585	ENOG4108YXA	Membrane
NOVO_04590	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
NOVO_04595	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
NOVO_04600	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
NOVO_04620	ENOG4107QN2	dihydrolipoyl dehydrogenase
NOVO_04625	ENOG4105KDC	50s ribosomal protein l28
NOVO_04630	ENOG41082FS	50S ribosomal protein L31
NOVO_04645	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
NOVO_04700	ENOG4105HMI	Membrane
NOVO_04710	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
NOVO_04715	ENOG4105C4M	(Ubiquinol oxidase) subunit I
NOVO_04745	ENOG4107QP8	phosphohexose isomerase
NOVO_04750	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
NOVO_04755	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
NOVO_04760	ENOG4108AWY	Nucleoside-diphosphate-sugar epimerase
NOVO_04775	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
NOVO_04800	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
NOVO_04805	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
NOVO_04830	ENOG4107ZH2	Coenzyme PQQ synthesis protein C
NOVO_04855	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
NOVO_04860	ENOG4105CKK	Glycosyl transferase, family 2
NOVO_04875	ENOG41083MR	nifu domain-containing protein
NOVO_04895	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
NOVO_04915	ENOG4105KWW	Biogenesis protein
NOVO_04920	ENOG4107QX9	Thiol disulfide interChange protein
NOVO_04925	ENOG4105DA4	cytochrome c-type biogenesis protein
NOVO_04945	ENOG4107QKV	phosphomannomutase
NOVO_04955	ENOG4108JJ6	Type I secretion system ATPase
NOVO_04965	ENOG4105F0N	pyrophosphate phospho-hydrolase
NOVO_04970	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
NOVO_04975	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
NOVO_04980	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
NOVO_04985	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
NOVO_04995	ENOG4105K59	histidine triad (HIT) protein
NOVO_05000	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
NOVO_05015	ENOG4105D7Z	glutathione synthase
NOVO_05020	ENOG4105BZU	Histidine kinase
NOVO_05025	ENOG4105BZU	Histidine kinase
NOVO_05045	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
NOVO_05050	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
NOVO_05060	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
NOVO_05075	ENOG4105DHZ	alpha beta
NOVO_05080	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
NOVO_05085	ENOG4107QI6	Cysteine desulfurase
NOVO_05090	ENOG4105C3J	Cysteine desulfurase
NOVO_05095	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
NOVO_05100	ENOG4108Z4V	iron-sulfur cluster assembly
NOVO_05105	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
NOVO_05110	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
NOVO_05140	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
NOVO_05155	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
NOVO_05165	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
NOVO_05175	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
NOVO_05180	ENOG4105BZ1	(ABC) transporter
NOVO_05195	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
NOVO_05200	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
NOVO_05215	ENOG4108NVR	Methyl-accepting chemotaxis
NOVO_05235	ENOG4105DFH	Transport of potassium into the cell (By similarity)
NOVO_05260	ENOG4105C8Y	Acetylornithine aminotransferase
NOVO_05265	ENOG4105DD5	Flagellar motor switch protein
NOVO_05275	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
NOVO_05280	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
NOVO_05315	ENOG4108NVM	synthesis repressor PhaR
NOVO_05320	ENOG4105BZU	Histidine kinase
NOVO_05365	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
NOVO_05370	ENOG4105C7I	Dehydrogenase
NOVO_05385	ENOG4105CSH	Transporter
NOVO_05390	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
NOVO_05395	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
NOVO_05400	ENOG4106D71	domain protein
NOVO_05405	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
NOVO_05430	ENOG4105CQ0	ABC transporter
NOVO_05455	ENOG4105CSH	Transporter
NOVO_05460	ENOG4105CHR	reductase
NOVO_05540	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
NOVO_05580	ENOG4105D1F	ATP-binding protein
NOVO_05585	ENOG4107QJR	hflk protein
NOVO_05590	ENOG4105EPW	hflc protein
NOVO_05625	ENOG4105EMU	Dehydrogenase
NOVO_05630	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
NOVO_05640	ENOG4108URH	decarboxylase
NOVO_05645	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
NOVO_05650	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
NOVO_05710	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
NOVO_05720	ENOG4105BZU	Histidine kinase
NOVO_05755	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
NOVO_05760	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
NOVO_05780	ENOG4105D6N	CoA-transferase, subunit a
NOVO_05820	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
NOVO_05835	ENOG4108Z6B	deaminase
NOVO_05840	ENOG41076HS	cation diffusion facilitator family transporter
NOVO_05845	ENOG4105MQ2	17 kDa surface antigen
NOVO_05860	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
NOVO_05865	ENOG4105CHR	reductase
NOVO_05880	ENOG4105K6T	rare lipoprotein A
NOVO_05890	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
NOVO_05900	ENOG4105YK5	50S ribosomal protein L36
NOVO_05905	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
NOVO_05910	ENOG4105C4R	Atp-dependent dna helicase
NOVO_05915	ENOG4105D52	delta-aminolevulinic acid dehydratase
NOVO_05930	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
NOVO_05935	ENOG4105BZ1	(ABC) transporter
NOVO_05940	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NOVO_05950	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
NOVO_05960	ENOG4108Z0R	Transferase
NOVO_05965	ENOG4105ESV	Glycosyl transferase, family 4
NOVO_05970	ENOG4105BZU	Histidine kinase
NOVO_06050	ENOG4105CB5	ATP-dependent DNA helicase recG
NOVO_06060	ENOG4105ER2	Ompa motb domain protein
NOVO_06065	ENOG4107RD7	Flagellar Motor Protein, MotA
NOVO_06075	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
NOVO_06095	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
NOVO_06100	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
NOVO_06105	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
NOVO_06110	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
NOVO_06115	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
NOVO_06120	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NOVO_06125	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
NOVO_06135	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
NOVO_06140	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
NOVO_06145	ENOG41083MP	50s ribosomal protein l29
NOVO_06150	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
NOVO_06155	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
NOVO_06165	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NOVO_06170	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
NOVO_06175	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
NOVO_06180	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
NOVO_06185	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
NOVO_06190	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
NOVO_06195	ENOG41084HQ	50S ribosomal protein L30
NOVO_06210	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
NOVO_06215	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NOVO_06220	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
NOVO_06225	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
NOVO_06230	ENOG4108ZT0	50S ribosomal protein l17
NOVO_06235	ENOG4105DFI	Membrane
NOVO_06245	ENOG4105WP5	
NOVO_06260	ENOG4105CJW	magnesium transporter
NOVO_06325	ENOG4107GD3	Catalyzes the conversion of acetoacetate to acetone and carbon dioxide (By similarity)
NOVO_06330	ENOG4105BZU	Histidine kinase
NOVO_06375	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
NOVO_06400	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
NOVO_06405	ENOG4105FDK	ABC transporter
NOVO_06415	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
NOVO_06425	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
NOVO_06430	ENOG4105F8V	Hydrolase, tatD family
NOVO_06445	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NOVO_06450	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
NOVO_06455	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
NOVO_06485	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
NOVO_06505	ENOG4105BZU	Histidine kinase
NOVO_06510	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
NOVO_06515	ENOG4108VYJ	response regulator receiver protein
NOVO_06520	ENOG4105YVF	chew protein
NOVO_06525	ENOG4105CBS	Chea signal transduction histidine kinase
NOVO_06550	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
NOVO_06555	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
NOVO_06570	ENOG4108VJ1	Transcriptional regulator (CarD family
NOVO_06575	ENOG4105C5F	glutamine synthetase
NOVO_06600	ENOG4105C83	adenylosuccinate lyase
NOVO_06605	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
NOVO_06610	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
NOVO_06615	ENOG4105M85	Bola protein
NOVO_06620	ENOG4105CFH	Aspartokinase
NOVO_06660	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
NOVO_06670	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
NOVO_06680	ENOG4105BZU	Histidine kinase
NOVO_06725	ENOG4108W6C	Dehydrogenase
NOVO_06740	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
NOVO_06745	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
NOVO_06750	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
NOVO_06755	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
NOVO_06760	ENOG4107QMP	dna polymerase iii subunits gamma and tau
NOVO_06785	ENOG4105C8N	cysteinyl-tRNA synthetase
NOVO_06790	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
NOVO_06850	ENOG4105C22	threonyL-tRNA synthetase
NOVO_06865	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
NOVO_06870	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
NOVO_06875	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
NOVO_06880	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
NOVO_06885	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
NOVO_06905	ENOG4105CJR	Integral membrane protein (MviN
NOVO_06920	ENOG4105DZ1	carboxypeptidase
NOVO_06925	ENOG4105DZ1	carboxypeptidase
NOVO_06930	ENOG4105C2C	drug resistance transporter, Bcr CflA
NOVO_06935	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
NOVO_06940	ENOG4105CW7	secretion protein, HlyD family
NOVO_06950	ENOG4105C8U	phosphate abc transporter
NOVO_06955	ENOG4105E2Z	phosphate ABC transporter (Permease
NOVO_06965	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
NOVO_06970	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NOVO_06990	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NOVO_07000	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
NOVO_07005	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
NOVO_07010	ENOG4105C5F	glutamine synthetase
NOVO_07040	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
NOVO_07065	ENOG4108JA2	transcriptioN-repair coupling factor
NOVO_07075	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
NOVO_07090	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
NOVO_07105	ENOG4105C5H	ABC transporter
NOVO_07135	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
NOVO_07140	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
NOVO_07145	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
NOVO_07170	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
NOVO_07175	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
NOVO_07190	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
NOVO_07225	ENOG4108JIR	Flagellum-specific ATP synthase
NOVO_07235	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
NOVO_07240	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
NOVO_07250	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
NOVO_07255	ENOG4105CI3	gtp-binding protein typa
NOVO_07270	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
NOVO_07285	ENOG4108NGE	Type IV secretion system protein VirB6
NOVO_07290	ENOG4108NGE	Type IV secretion system protein VirB6
NOVO_07295	ENOG4108NG5	type IV secretion system protein
NOVO_07310	ENOG4108QTG	type IV secretion system protein
NOVO_07325	ENOG4108JPZ	Monovalent cation H antiporter subunit D
NOVO_07355	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
NOVO_07385	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
NOVO_07400	ENOG4105D1Q	UPF0246 protein
NOVO_07425	ENOG4105BZU	Histidine kinase
NOVO_07430	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
NOVO_07435	ENOG4105I03	Flagellin
NOVO_07460	ENOG4105CUY	Mechanosensitive ion channel
NOVO_07470	ENOG4105EMU	Dehydrogenase
NOVO_07480	ENOG4105BZU	Histidine kinase
NOVO_07485	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
NOVO_07490	ENOG4107QX3	carboxylase
NOVO_07495	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
NOVO_07500	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
NOVO_07540	ENOG4107YXZ	hydrolase, family 25
NOVO_07545	ENOG4105EFC	phage portal protein HK97 family
NOVO_07555	ENOG4105BZU	Histidine kinase
NOVO_07570	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
NOVO_07575	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
NOVO_07580	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
NOVO_07625	ENOG4108UJU	UPF0301 protein
NOVO_07630	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
NOVO_07650	ENOG4105N82	Endonuclease
NOVO_07670	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NOVO_07675	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
NOVO_07685	ENOG4107R1I	NAD-dependent malic enzyme
NOVO_07695	ENOG4105C75	arginyL-tRNA synthetase
NOVO_07700	ENOG4105D1H	recombination factor protein RarA
NOVO_07760	ENOG4105BZU	Histidine kinase
NOVO_07770	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
NOVO_07780	ENOG4105BZU	Histidine kinase
NOVO_07795	ENOG4105BZU	Histidine kinase
NOVO_07865	ENOG4105BZU	Histidine kinase
NOVO_07870	ENOG41066YJ	Beta-lactamase
NOVO_07910	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
NOVO_07920	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NOVO_07945	ENOG4106HA5	Protein of unknown function (DUF2497) 
NOVO_07955	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
NOVO_07960	ENOG4105CFG	Acts as a chaperone (By similarity)
NOVO_07965	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
NOVO_07975	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
NOVO_08005	ENOG4108R6K	riboflavin synthase, subunit alpha
NOVO_08010	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
NOVO_08020	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
NOVO_08030	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
NOVO_08060	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
NOVO_08065	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NOVO_08070	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
NOVO_08075	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NOVO_08080	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
NOVO_08085	ENOG4105GKE	subunit e
NOVO_08095	ENOG4107QIZ	NADH dehydrogenase
NOVO_08110	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
NOVO_08120	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
NOVO_08130	ENOG4105C8S	subunit m
NOVO_08135	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
NOVO_08140	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
NOVO_08145	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
NOVO_08155	ENOG4105C6K	Malic enzyme
NOVO_08160	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
NOVO_08195	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
NOVO_08200	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
NOVO_08210	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
NOVO_08235	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
NOVO_08245	ENOG4105CJN	penicillin-binding protein
NOVO_08250	ENOG4105D4A	Cell wall formation (By similarity)
NOVO_08265	ENOG4105C72	UPF0176 protein
NOVO_08275	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
NOVO_08285	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
NOVO_08295	ENOG4105E4C	Lytic transglycosylase catalytic
NOVO_08300	ENOG4105C26	Dehydrogenase
NOVO_08305	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
NOVO_08340	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
NOVO_08450	ENOG4105DFS	Conserved Protein
NOVO_08480	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
NOVO_08500	ENOG4105CTD	carboxy-peptidase
NOVO_08565	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NOVO_08580	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
NOVO_08600	ENOG4105DWF	phosphomethylpyrimidine kinase
NOVO_08610	ENOG4107QJE	Chromosome Partitioning Protein
NOVO_08630	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
NOVO_08660	ENOG4105BZU	Histidine kinase
NOVO_08665	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
NOVO_08670	ENOG4105D00	flagellar biosynthetic protein flhB
NOVO_08680	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
NOVO_08685	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
NOVO_08690	ENOG4105CUT	histidyl-tRNA synthetase
NOVO_08745	ENOG4107G9V	glycosyl transferase, family 39
NOVO_08780	ENOG4107YXZ	hydrolase, family 25
NOVO_08785	ENOG4105EFC	phage portal protein HK97 family
NOVO_08805	ENOG4108JJ7	ABC transporter
NOVO_08840	ENOG4105EE5	Membrane protein terC
NOVO_08880	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
NOVO_08890	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
NOVO_08895	ENOG4105NXV	High-affinity zinc uptake system protein
NOVO_08900	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
NOVO_08905	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
NOVO_08910	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
NOVO_08920	ENOG4105DJV	ribulose-phosphate 3-epimerase
NOVO_08925	ENOG4105W62	Domain of unknown function (DUF2610)
NOVO_09000	ENOG4105CN7	Flagellar biosynthetic protein FliP
NOVO_09015	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
NOVO_09080	ENOG4106678	morphogenetic protein associated with SpoVID
NOVO_09105	ENOG4105D1F	ATP-binding protein
NOVO_09175	ENOG4105DFS	Conserved Protein
NOVO_09405	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
NOVO_09440	ENOG4105EY8	ABC transporter