locus-tag	class	description
NOVO_00015	COG3335	DDE superfamily endonuclease
NOVO_00030	COG0666	response to abiotic stimulus
NOVO_00040	COG1823	symporter activity
NOVO_00050	COG2001	Belongs to the MraZ family
NOVO_00075	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NOVO_00085	COG3335	DDE superfamily endonuclease
NOVO_00160	COG0372	Belongs to the citrate synthase family
NOVO_00170	COG3335	DDE superfamily endonuclease
NOVO_00200	COG0163	prenyltransferase activity
NOVO_00205	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NOVO_00210	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NOVO_00220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NOVO_00245	COG3335	DDE superfamily endonuclease
NOVO_00260	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NOVO_00270	COG0450	alkyl hydroperoxide reductase
NOVO_00275	COG0492	ferredoxin-NADP+ reductase activity
NOVO_00350	COG1752	Esterase of the alpha-beta hydrolase superfamily
NOVO_00365	COG3335	DDE superfamily endonuclease
NOVO_00520	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NOVO_00550	COG3335	DDE superfamily endonuclease
NOVO_00575	COG0288	reversible hydration of carbon dioxide
NOVO_00590	COG3335	DDE superfamily endonuclease
NOVO_00610	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NOVO_00615	COG1758	RNA polymerase activity
NOVO_00625	COG3335	DDE superfamily endonuclease
NOVO_00650	COG0351	phosphomethylpyrimidine kinase
NOVO_00655	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NOVO_00675	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NOVO_00680	COG3335	DDE superfamily endonuclease
NOVO_00695	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NOVO_00705	COG2081	HI0933 family
NOVO_00715	COG0666	response to abiotic stimulus
NOVO_00730	COG1570	exodeoxyribonuclease VII activity
NOVO_00735	COG2835	tetraacyldisaccharide 4'-kinase activity
NOVO_00745	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NOVO_00760	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
NOVO_00780	COG1792	Involved in formation and maintenance of cell shape
NOVO_00805	COG2204	response regulator
NOVO_00810	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NOVO_00815	COG1881	PFAM PEBP family protein
NOVO_00825	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NOVO_00830	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NOVO_00840	COG3335	DDE superfamily endonuclease
NOVO_00875	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NOVO_00885	COG2927	DNA polymerase III (CHI subunit)
NOVO_00890	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NOVO_00895	COG0586	Pfam SNARE associated Golgi protein
NOVO_00900	COG1331	Highly conserved protein containing a thioredoxin domain
NOVO_00935	COG0670	Belongs to the BI1 family
NOVO_00955	COG5002	protein histidine kinase activity
NOVO_00970	COG3335	DDE superfamily endonuclease
NOVO_01000	COG3335	DDE superfamily endonuclease
NOVO_01015	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NOVO_01020	COG0204	Acyl-transferase
NOVO_01025	COG2967	ApaG domain
NOVO_01045	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NOVO_01070	COG0758	DNA mediated transformation
NOVO_01075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NOVO_01120	COG3335	DDE superfamily endonuclease
NOVO_01160	COG3335	DDE superfamily endonuclease
NOVO_01195	COG3118	belongs to the thioredoxin family
NOVO_01255	COG3335	DDE superfamily endonuclease
NOVO_01285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NOVO_01340	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NOVO_01360	COG0018	arginyl-trna synthetase
NOVO_01405	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NOVO_01410	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NOVO_01420	COG0628	permease
NOVO_01430	COG0335	large ribosomal subunit rRNA binding
NOVO_01465	COG4786	Flagellar basal body rod
NOVO_01470	COG3335	DDE superfamily endonuclease
NOVO_01485	COG0697	spore germination
NOVO_01490	COG1845	cytochrome c oxidase, subunit III
NOVO_01505	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NOVO_01510	COG0805	protein transport
NOVO_01525	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NOVO_01530	COG0723	plastoquinol--plastocyanin reductase activity
NOVO_01545	COG0156	8-amino-7-oxononanoate synthase activity
NOVO_01550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NOVO_01560	COG2807	transmembrane transport
NOVO_01575	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NOVO_01585	COG0742	ribosomal rna small subunit methyltransferase
NOVO_01590	COG1187	pseudouridine synthase activity
NOVO_01595	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NOVO_01600	COG0477	Major facilitator Superfamily
NOVO_01605	COG0708	Exodeoxyribonuclease III
NOVO_01610	COG0330	HflC and HflK could
NOVO_01625	COG1301	dicarboxylic acid transport
NOVO_01635	COG0589	response to stress
NOVO_01640	COG0142	geranyltranstransferase activity
NOVO_01645	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NOVO_01655	COG0772	Belongs to the SEDS family
NOVO_01715	COG4962	Type ii secretion system protein e
NOVO_01730	COG3451	type IV secretory pathway VirB4
NOVO_01755	COG3701	Conjugal transfer protein
NOVO_01760	COG3504	Conjugal transfer protein
NOVO_01795	COG3335	DDE superfamily endonuclease
NOVO_01800	COG0653	protein targeting
NOVO_01805	COG3335	DDE superfamily endonuclease
NOVO_01815	COG1704	LemA family
NOVO_01820	COG0539	negative regulation of cytoplasmic translation
NOVO_01830	COG0071	Belongs to the small heat shock protein (HSP20) family
NOVO_01870	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NOVO_01885	COG0540	Belongs to the ATCase OTCase family
NOVO_01910	COG5632	N-Acetylmuramoyl-L-alanine amidase
NOVO_01910	COG3409	Peptidoglycan-binding domain 1 protein
NOVO_01920	COG3335	DDE superfamily endonuclease
NOVO_01925	COG0442	prolyl-tRNA aminoacylation
NOVO_01935	COG2027	D-alanyl-D-alanine carboxypeptidase
NOVO_01940	COG0552	protein localization to endoplasmic reticulum
NOVO_01945	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NOVO_01950	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NOVO_01955	COG0305	Participates in initiation and elongation during chromosome replication
NOVO_02090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NOVO_02105	COG0653	protein targeting
NOVO_02150	COG0009	L-threonylcarbamoyladenylate synthase
NOVO_02155	COG1185	polyribonucleotide nucleotidyltransferase activity
NOVO_02160	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NOVO_02165	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NOVO_02175	COG0698	ribose 5-phosphate isomerase
NOVO_02190	COG0750	zinc metalloprotease
NOVO_02195	COG0039	L-malate dehydrogenase activity
NOVO_02200	COG0587	DNA-directed DNA polymerase activity
NOVO_02210	COG1250	3-hydroxyacyl-CoA dehydrogenase
NOVO_02210	COG1024	Enoyl-CoA hydratase
NOVO_02240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NOVO_02240	COG0072	phenylalanine-tRNA ligase activity
NOVO_02245	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NOVO_02255	COG1530	ribonuclease E activity
NOVO_02275	COG0504	CTP synthase activity
NOVO_02285	COG0149	triose-phosphate isomerase activity
NOVO_02295	COG1278	Cold shock
NOVO_02310	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NOVO_02325	COG0181	hydroxymethylbilane synthase activity
NOVO_02330	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NOVO_02345	COG3451	type IV secretory pathway VirB4
NOVO_02375	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
NOVO_02395	COG0471	metal ion transport
NOVO_02400	COG1573	uracil-dna glycosylase
NOVO_02405	COG1674	ftsk spoiiie
NOVO_02410	COG1494	fructose-1,6-bisphosphatase
NOVO_02420	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NOVO_02425	COG1396	sequence-specific DNA binding
NOVO_02430	COG0012	GTP binding
NOVO_02440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NOVO_02450	COG0571	ribonuclease III activity
NOVO_02455	COG0681	Belongs to the peptidase S26 family
NOVO_02460	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NOVO_02465	COG0704	Plays a role in the regulation of phosphate uptake
NOVO_02470	COG0616	signal peptide processing
NOVO_02475	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NOVO_02490	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NOVO_02500	COG0483	inositol monophosphate 1-phosphatase activity
NOVO_02505	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NOVO_02510	COG1830	Aldolase
NOVO_02545	COG1558	bacterial-type flagellum-dependent cell motility
NOVO_02555	COG1987	bacterial-type flagellum assembly
NOVO_02580	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NOVO_02585	COG5599	Phosphatase
NOVO_02590	COG1770	oligopeptidase
NOVO_02600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NOVO_02600	COG2169	Transcriptional regulator
NOVO_02605	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NOVO_02610	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NOVO_02630	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NOVO_02640	COG0222	ribosome binding
NOVO_02645	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NOVO_02655	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NOVO_02660	COG0250	Participates in transcription elongation, termination and antitermination
NOVO_02675	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NOVO_02685	COG0049	tRNA binding
NOVO_02690	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NOVO_02700	COG0321	lipoyl(octanoyl) transferase activity
NOVO_02700	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NOVO_02705	COG0671	phosphoesterase, PA-phosphatase related
NOVO_02720	COG0697	spore germination
NOVO_02725	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NOVO_02740	COG1546	Belongs to the CinA family
NOVO_02740	COG1058	Belongs to the CinA family
NOVO_02745	COG0024	Methionine aminopeptidase
NOVO_02750	COG2003	Belongs to the UPF0758 family
NOVO_02765	COG1301	dicarboxylic acid transport
NOVO_02775	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NOVO_02780	COG1074	ATP-dependent DNA helicase activity
NOVO_02805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NOVO_02810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NOVO_02830	COG3335	DDE superfamily endonuclease
NOVO_02840	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NOVO_02845	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NOVO_02850	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NOVO_02865	COG3335	DDE superfamily endonuclease
NOVO_02880	COG0525	valine-tRNA ligase activity
NOVO_02885	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NOVO_02890	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NOVO_02900	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NOVO_02905	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NOVO_02905	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NOVO_02915	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NOVO_02925	COG0356	it plays a direct role in the translocation of protons across the membrane
NOVO_02940	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NOVO_02950	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
NOVO_02955	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NOVO_02960	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
NOVO_02965	COG2076	Multidrug Resistance protein
NOVO_02975	COG2853	Lipoprotein
NOVO_03030	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NOVO_03040	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NOVO_03045	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
NOVO_03050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NOVO_03060	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NOVO_03065	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NOVO_03075	COG1324	tolerance protein
NOVO_03110	COG1056	cytidyltransferase-related domain
NOVO_03110	COG1051	belongs to the nudix hydrolase family
NOVO_03130	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NOVO_03140	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NOVO_03145	COG0196	riboflavin kinase activity
NOVO_03160	COG0528	UMP kinase activity
NOVO_03165	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NOVO_03170	COG0052	Belongs to the universal ribosomal protein uS2 family
NOVO_03180	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NOVO_03185	COG0849	cell division
NOVO_03205	COG3158	transport of potassium into the cell
NOVO_03215	COG3335	DDE superfamily endonuclease
NOVO_03235	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NOVO_03240	COG1127	ABC transporter
NOVO_03250	COG0302	gtp cyclohydrolase
NOVO_03255	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NOVO_03260	COG0799	negative regulation of ribosome biogenesis
NOVO_03265	COG0156	8-amino-7-oxononanoate synthase activity
NOVO_03275	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NOVO_03280	COG2226	methyltransferase
NOVO_03305	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NOVO_03315	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NOVO_03325	COG3047	cAMP biosynthetic process
NOVO_03330	COG1126	abc transporter atp-binding protein
NOVO_03335	COG0765	amino acid transport
NOVO_03340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NOVO_03345	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NOVO_03360	COG0745	RESPONSE REGULATOR receiver
NOVO_03370	COG2823	Periplasmic or secreted lipoprotein
NOVO_03375	COG1295	ribonuclease BN
NOVO_03385	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
NOVO_03390	COG2948	multi-organism process
NOVO_03400	COG3736	Type IV secretory pathway, component VirB8
NOVO_03405	COG1253	flavin adenine dinucleotide binding
NOVO_03410	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NOVO_03415	COG1702	phosphate starvation-inducible protein PhoH
NOVO_03440	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NOVO_03445	COG0594	ribonuclease P activity
NOVO_03450	COG1511	domain protein
NOVO_03450	COG3264	Mechanosensitive ion channel
NOVO_03460	COG3335	DDE superfamily endonuclease
NOVO_03485	COG4208	sulfate ABC transporter
NOVO_03490	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NOVO_03505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NOVO_03525	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NOVO_03550	COG2867	negative regulation of translational initiation
NOVO_03590	COG0285	dihydrofolate synthase activity
NOVO_03595	COG0284	orotidine-5'-phosphate decarboxylase activity
NOVO_03605	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NOVO_03610	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NOVO_03610	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NOVO_03615	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NOVO_03620	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NOVO_03625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NOVO_03635	COG1028	Short-chain dehydrogenase reductase Sdr
NOVO_03640	COG0473	3-isopropylmalate dehydrogenase activity
NOVO_03645	COG1132	(ABC) transporter
NOVO_03655	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NOVO_03665	COG3706	GGDEF domain
NOVO_03670	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NOVO_03675	COG4536	flavin adenine dinucleotide binding
NOVO_03680	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NOVO_03685	COG4974	Belongs to the 'phage' integrase family
NOVO_03705	COG3047	cAMP biosynthetic process
NOVO_03730	COG0598	Magnesium transport protein CorA
NOVO_03750	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NOVO_03765	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NOVO_03785	COG0745	RESPONSE REGULATOR receiver
NOVO_03820	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NOVO_03830	COG0138	bifunctional purine biosynthesis protein purh
NOVO_03840	COG0848	biopolymer transport protein
NOVO_03850	COG1137	ATPase activity
NOVO_03865	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NOVO_03865	COG0517	IMP dehydrogenase activity
NOVO_03885	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NOVO_03890	COG4964	Belongs to the GSP D family
NOVO_03900	COG0105	UTP biosynthetic process
NOVO_03920	COG0494	nUDIX hydrolase
NOVO_03930	COG0793	Belongs to the peptidase S41A family
NOVO_03935	COG3706	GGDEF domain
NOVO_03935	COG0745	RESPONSE REGULATOR receiver
NOVO_03945	COG0508	dehydrogenase complex catalyzes the overall conversion of
NOVO_03950	COG0022	dehydrogenase e1 component
NOVO_03955	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NOVO_03960	COG0531	amino acid
NOVO_03965	COG0531	amino acid
NOVO_03975	COG0142	geranyltranstransferase activity
NOVO_03995	COG3335	DDE superfamily endonuclease
NOVO_04010	COG1192	Involved in chromosome partitioning
NOVO_04040	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
NOVO_04045	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NOVO_04055	COG0556	nucleotide-excision repair
NOVO_04090	COG0736	holo-[acyl-carrier-protein] synthase activity
NOVO_04095	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NOVO_04100	COG0564	pseudouridine synthase activity
NOVO_04120	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NOVO_04125	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NOVO_04135	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NOVO_04140	COG0438	transferase activity, transferring glycosyl groups
NOVO_04150	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NOVO_04150	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NOVO_04155	COG0606	chelatase, subunit chli
NOVO_04160	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NOVO_04165	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NOVO_04170	COG0519	Catalyzes the synthesis of GMP from XMP
NOVO_04170	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NOVO_04175	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NOVO_04180	COG0792	nuclease activity
NOVO_04210	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NOVO_04235	COG0795	lipopolysaccharide-transporting ATPase activity
NOVO_04245	COG2255	four-way junction helicase activity
NOVO_04250	COG0632	four-way junction helicase activity
NOVO_04255	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NOVO_04265	COG0424	maF-like protein
NOVO_04285	COG1192	Involved in chromosome partitioning
NOVO_04290	COG0357	Ribosomal RNA small subunit methyltransferase G
NOVO_04295	COG0445	tRNA wobble uridine modification
NOVO_04300	COG0463	Glycosyl transferase, family 2
NOVO_04320	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NOVO_04325	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NOVO_04335	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NOVO_04355	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NOVO_04355	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NOVO_04365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NOVO_04375	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NOVO_04385	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NOVO_04390	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NOVO_04400	COG2202	Pas domain
NOVO_04400	COG2205	protein histidine kinase activity
NOVO_04405	COG3437	response regulator, receiver
NOVO_04425	COG0823	Involved in the tonB-independent uptake of proteins
NOVO_04435	COG2885	chlorophyll binding
NOVO_04450	COG0242	peptide deformylase activity
NOVO_04460	COG1279	arginine transmembrane transporter activity
NOVO_04465	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NOVO_04470	COG1053	succinate dehydrogenase
NOVO_04480	COG2009	succinate dehydrogenase
NOVO_04485	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NOVO_04500	COG0802	atpase or kinase
NOVO_04505	COG0840	transmembrane signaling receptor activity
NOVO_04520	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NOVO_04540	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NOVO_04545	COG3279	Response regulator of the LytR AlgR family
NOVO_04560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NOVO_04565	COG0237	dephospho-CoA kinase activity
NOVO_04590	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NOVO_04595	COG0039	L-malate dehydrogenase activity
NOVO_04600	COG0045	succinate-CoA ligase (ADP-forming) activity
NOVO_04610	COG0567	Dehydrogenase, E1 component
NOVO_04620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NOVO_04625	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NOVO_04630	COG0254	rRNA binding
NOVO_04645	COG0328	RNA-DNA hybrid ribonuclease activity
NOVO_04685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NOVO_04690	COG3335	DDE superfamily endonuclease
NOVO_04700	COG2855	membrane
NOVO_04705	COG4890	Cyd operon protein YbgT
NOVO_04710	COG1294	oxidase, subunit
NOVO_04745	COG0166	Belongs to the GPI family
NOVO_04750	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NOVO_04760	COG3660	Nucleoside-diphosphate-sugar epimerase
NOVO_04770	COG1028	Short-chain dehydrogenase reductase Sdr
NOVO_04775	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NOVO_04800	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NOVO_04830	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
NOVO_04855	COG2264	protein methyltransferase activity
NOVO_04860	COG0463	Glycosyl transferase, family 2
NOVO_04870	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NOVO_04875	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NOVO_04895	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NOVO_04915	COG3088	subunit of a heme lyase
NOVO_04925	COG1138	Cytochrome C-type biogenesis protein
NOVO_04945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NOVO_04950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NOVO_04965	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NOVO_04970	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NOVO_04975	COG0360	Binds together with S18 to 16S ribosomal RNA
NOVO_04985	COG0359	binds to the 23S rRNA
NOVO_05000	COG0101	tRNA pseudouridine synthase activity
NOVO_05015	COG0189	ligase activity
NOVO_05020	COG5002	protein histidine kinase activity
NOVO_05020	COG2205	protein histidine kinase activity
NOVO_05020	COG0784	Response regulator, receiver
NOVO_05025	COG4251	negative regulation of phosphorylation
NOVO_05040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NOVO_05045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NOVO_05050	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NOVO_05060	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NOVO_05075	COG2945	thiolester hydrolase activity
NOVO_05080	COG1959	2 iron, 2 sulfur cluster binding
NOVO_05085	COG1104	cysteine desulfurase activity
NOVO_05095	COG0822	iron-sulfur transferase activity
NOVO_05100	COG0316	Belongs to the HesB IscA family
NOVO_05105	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NOVO_05110	COG0443	Heat shock 70 kDa protein
NOVO_05130	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NOVO_05140	COG0297	glycogen (starch) synthase activity
NOVO_05155	COG0519	Catalyzes the synthesis of GMP from XMP
NOVO_05165	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NOVO_05175	COG0312	modulator of DNA gyrase
NOVO_05180	COG1132	(ABC) transporter
NOVO_05190	COG0400	carboxylic ester hydrolase activity
NOVO_05195	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NOVO_05200	COG0154	amidase activity
NOVO_05235	COG3158	transport of potassium into the cell
NOVO_05240	COG3335	DDE superfamily endonuclease
NOVO_05260	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NOVO_05265	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NOVO_05275	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NOVO_05280	COG1766	The M ring may be actively involved in energy transduction
NOVO_05290	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NOVO_05300	COG1322	Protein conserved in bacteria
NOVO_05310	COG0408	coproporphyrinogen oxidase activity
NOVO_05315	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
NOVO_05365	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NOVO_05370	COG2902	Dehydrogenase
NOVO_05385	COG0477	Major facilitator Superfamily
NOVO_05390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NOVO_05395	COG2171	N-acyltransferase activity
NOVO_05405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NOVO_05430	COG4178	(ABC) transporter
NOVO_05455	COG0477	Major facilitator Superfamily
NOVO_05460	COG1028	Short-chain dehydrogenase reductase Sdr
NOVO_05485	COG3335	DDE superfamily endonuclease
NOVO_05540	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NOVO_05550	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NOVO_05580	COG0489	protein tyrosine kinase activity
NOVO_05585	COG0330	HflC and HflK could
NOVO_05590	COG0330	HflC and HflK could
NOVO_05625	COG4221	oxidoreductase activity
NOVO_05630	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NOVO_05645	COG0688	phosphatidylethanolamine metabolic process
NOVO_05650	COG1183	phosphatidylcholine synthase activity
NOVO_05675	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NOVO_05710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NOVO_05720	COG5002	protein histidine kinase activity
NOVO_05755	COG3243	poly(R)-hydroxyalkanoic acid synthase
NOVO_05760	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NOVO_05775	COG1214	PFAM Peptidase M22, glycoprotease
NOVO_05780	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NOVO_05790	COG2194	sulfuric ester hydrolase activity
NOVO_05820	COG0542	response to heat
NOVO_05835	COG0590	tRNA wobble adenosine to inosine editing
NOVO_05840	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NOVO_05860	COG0019	diaminopimelate decarboxylase activity
NOVO_05865	COG1028	Short-chain dehydrogenase reductase Sdr
NOVO_05880	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NOVO_05885	COG0493	'glutamate synthase
NOVO_05885	COG0543	2 iron, 2 sulfur cluster binding
NOVO_05890	COG0148	phosphopyruvate hydratase activity
NOVO_05905	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NOVO_05910	COG0210	DNA helicase
NOVO_05915	COG0113	porphobilinogen synthase activity
NOVO_05930	COG0312	modulator of DNA gyrase
NOVO_05935	COG1132	(ABC) transporter
NOVO_05940	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NOVO_05950	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NOVO_05960	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NOVO_05965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NOVO_05970	COG5002	protein histidine kinase activity
NOVO_05980	COG3335	DDE superfamily endonuclease
NOVO_06005	COG3335	DDE superfamily endonuclease
NOVO_06025	COG3335	DDE superfamily endonuclease
NOVO_06050	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NOVO_06065	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NOVO_06075	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NOVO_06080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NOVO_06095	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NOVO_06100	COG0051	transcription antitermination factor activity, RNA binding
NOVO_06115	COG0089	rRNA binding
NOVO_06120	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NOVO_06125	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NOVO_06135	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NOVO_06140	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NOVO_06145	COG0255	Belongs to the universal ribosomal protein uL29 family
NOVO_06155	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NOVO_06160	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NOVO_06165	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NOVO_06175	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NOVO_06180	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NOVO_06195	COG1841	ribosomal large subunit assembly
NOVO_06210	COG0563	adenylate kinase activity
NOVO_06215	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NOVO_06220	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NOVO_06230	COG0203	ribosomal protein L17
NOVO_06235	COG0697	spore germination
NOVO_06245	COG4633	Protein conserved in bacteria
NOVO_06260	COG2239	Acts as a magnesium transporter
NOVO_06285	COG3335	DDE superfamily endonuclease
NOVO_06325	COG4689	acetoacetate decarboxylase
NOVO_06330	COG5002	protein histidine kinase activity
NOVO_06375	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NOVO_06380	COG2194	sulfuric ester hydrolase activity
NOVO_06415	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NOVO_06425	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NOVO_06430	COG0084	hydrolase, TatD family'
NOVO_06435	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NOVO_06450	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NOVO_06455	COG0316	Belongs to the HesB IscA family
NOVO_06485	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NOVO_06490	COG3504	Conjugal transfer protein
NOVO_06500	COG0114	fumarate hydratase activity
NOVO_06505	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NOVO_06510	COG2201	protein-glutamate methylesterase activity
NOVO_06520	COG0835	chemotaxis
NOVO_06525	COG0643	Histidine kinase
NOVO_06525	COG2198	Histidine kinase
NOVO_06550	COG0358	DNA primase activity
NOVO_06555	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NOVO_06570	COG1329	Transcriptional regulator
NOVO_06600	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NOVO_06605	COG1218	3'(2'),5'-bisphosphate nucleotidase
NOVO_06610	COG1381	Involved in DNA repair and RecF pathway recombination
NOVO_06615	COG0271	Belongs to the BolA IbaG family
NOVO_06660	COG2226	methyltransferase
NOVO_06670	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NOVO_06680	COG5002	protein histidine kinase activity
NOVO_06700	COG3335	DDE superfamily endonuclease
NOVO_06720	COG0194	GDP metabolic process
NOVO_06725	COG0300	oxidoreductase activity
NOVO_06740	COG3243	poly(R)-hydroxyalkanoic acid synthase
NOVO_06745	COG0745	RESPONSE REGULATOR receiver
NOVO_06750	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NOVO_06755	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NOVO_06785	COG0215	cysteine-tRNA ligase activity
NOVO_06790	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
NOVO_06825	COG3335	DDE superfamily endonuclease
NOVO_06850	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NOVO_06865	COG0616	signal peptide processing
NOVO_06865	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NOVO_06870	COG0752	glycyl-tRNA synthetase alpha subunit
NOVO_06880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NOVO_06880	COG0574	Belongs to the PEP-utilizing enzyme family
NOVO_06885	COG2204	response regulator
NOVO_06905	COG0728	peptidoglycan biosynthetic process
NOVO_06920	COG1686	Belongs to the peptidase S11 family
NOVO_06925	COG1686	Belongs to the peptidase S11 family
NOVO_06930	COG2814	Major facilitator Superfamily
NOVO_06935	COG2814	Major facilitator Superfamily
NOVO_06940	COG1566	PFAM secretion protein HlyD family protein
NOVO_06950	COG0573	inorganic phosphate transmembrane transporter activity
NOVO_06955	COG0581	inorganic phosphate transmembrane transporter activity
NOVO_06965	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NOVO_06970	COG0745	RESPONSE REGULATOR receiver
NOVO_06980	COG0271	Belongs to the BolA IbaG family
NOVO_06990	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NOVO_07005	COG0740	serine-type endopeptidase activity
NOVO_07010	COG0174	glutamine synthetase
NOVO_07030	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NOVO_07060	COG2070	2-Nitropropane dioxygenase
NOVO_07065	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NOVO_07090	COG0653	protein targeting
NOVO_07105	COG0488	(ABC) transporter
NOVO_07115	COG3335	DDE superfamily endonuclease
NOVO_07130	COG0564	pseudouridine synthase activity
NOVO_07135	COG1573	uracil-dna glycosylase
NOVO_07140	COG0167	dihydroorotate dehydrogenase activity
NOVO_07145	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NOVO_07170	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NOVO_07175	COG0756	dUTP diphosphatase activity
NOVO_07190	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NOVO_07210	COG3335	DDE superfamily endonuclease
NOVO_07225	COG1157	protein secretion by the type III secretion system
NOVO_07235	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NOVO_07240	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NOVO_07245	COG0193	aminoacyl-tRNA hydrolase activity
NOVO_07250	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NOVO_07270	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NOVO_07280	COG3451	type IV secretory pathway VirB4
NOVO_07285	COG3704	protein secretion by the type IV secretion system
NOVO_07290	COG3704	protein secretion by the type IV secretion system
NOVO_07295	COG3704	protein secretion by the type IV secretion system
NOVO_07305	COG3704	protein secretion by the type IV secretion system
NOVO_07310	COG3704	protein secretion by the type IV secretion system
NOVO_07310	COG1340	protein secretion by the type IV secretion system
NOVO_07325	COG0651	ATP synthesis coupled electron transport
NOVO_07345	COG1519	Transferase
NOVO_07355	COG3023	N-Acetylmuramoyl-L-alanine amidase
NOVO_07365	COG3335	DDE superfamily endonuclease
NOVO_07385	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NOVO_07390	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NOVO_07400	COG3022	response to hydroperoxide
NOVO_07425	COG5002	protein histidine kinase activity
NOVO_07430	COG2852	Protein conserved in bacteria
NOVO_07460	COG0668	transmembrane transport
NOVO_07470	COG4221	oxidoreductase activity
NOVO_07480	COG2202	Pas domain
NOVO_07480	COG2205	protein histidine kinase activity
NOVO_07485	COG0439	Biotin carboxylase
NOVO_07490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NOVO_07495	COG0584	glycerophosphoryl diester phosphodiesterase
NOVO_07500	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NOVO_07535	COG3335	DDE superfamily endonuclease
NOVO_07540	COG3757	hydrolase, family 25
NOVO_07540	COG3409	Peptidoglycan-binding domain 1 protein
NOVO_07545	COG4695	Portal protein
NOVO_07555	COG2200	EAL domain
NOVO_07570	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NOVO_07575	COG1684	flagellar biosynthetic protein fliR
NOVO_07580	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NOVO_07625	COG1678	Uncharacterized ACR, COG1678
NOVO_07630	COG4232	protein-disulfide reductase activity
NOVO_07650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NOVO_07670	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NOVO_07675	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NOVO_07685	COG0281	malic enzyme
NOVO_07695	COG0018	arginyl-trna synthetase
NOVO_07700	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NOVO_07710	COG3335	DDE superfamily endonuclease
NOVO_07730	COG3335	DDE superfamily endonuclease
NOVO_07745	COG0784	Response regulator, receiver
NOVO_07760	COG5002	protein histidine kinase activity
NOVO_07770	COG3483	tryptophan 2,3-dioxygenase activity
NOVO_07780	COG5002	protein histidine kinase activity
NOVO_07795	COG5002	protein histidine kinase activity
NOVO_07865	COG5002	protein histidine kinase activity
NOVO_07870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NOVO_07895	COG3335	DDE superfamily endonuclease
NOVO_07910	COG0544	peptidyl-prolyl cis-trans isomerase activity
NOVO_07920	COG0617	tRNA 3'-terminal CCA addition
NOVO_07945	COG3827	peptidoglycan binding
NOVO_07960	COG0443	Heat shock 70 kDa protein
NOVO_07975	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NOVO_07990	COG0196	riboflavin kinase activity
NOVO_08005	COG0307	riboflavin synthase, alpha
NOVO_08010	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NOVO_08010	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NOVO_08015	COG0840	transmembrane signaling receptor activity
NOVO_08020	COG0604	alcohol dehydrogenase
NOVO_08030	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NOVO_08060	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NOVO_08065	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NOVO_08075	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NOVO_08080	COG0649	NAD binding
NOVO_08085	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
NOVO_08095	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NOVO_08100	COG1034	ATP synthesis coupled electron transport
NOVO_08105	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NOVO_08110	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NOVO_08115	COG0839	Belongs to the complex I subunit 6 family
NOVO_08125	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NOVO_08140	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NOVO_08140	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NOVO_08155	COG0281	malic enzyme
NOVO_08155	COG0280	phosphate acetyltransferase
NOVO_08160	COG0268	Binds directly to 16S ribosomal RNA
NOVO_08170	COG1862	Preprotein translocase
NOVO_08200	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NOVO_08210	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NOVO_08245	COG0768	penicillin binding
NOVO_08250	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NOVO_08275	COG0592	DNA-directed DNA polymerase activity
NOVO_08285	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NOVO_08295	COG0741	lytic transglycosylase activity
NOVO_08305	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NOVO_08310	COG3335	DDE superfamily endonuclease
NOVO_08335	COG3335	DDE superfamily endonuclease
NOVO_08340	COG0653	protein targeting
NOVO_08375	COG3335	DDE superfamily endonuclease
NOVO_08450	COG4804	nuclease activity
NOVO_08485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NOVO_08500	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NOVO_08565	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NOVO_08580	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NOVO_08600	COG0351	phosphomethylpyrimidine kinase
NOVO_08600	COG0352	thiamine-phosphate diphosphorylase activity
NOVO_08600	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NOVO_08605	COG0783	Belongs to the Dps family
NOVO_08610	COG1192	Involved in chromosome partitioning
NOVO_08625	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NOVO_08630	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NOVO_08665	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NOVO_08670	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NOVO_08680	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NOVO_08685	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NOVO_08710	COG3335	DDE superfamily endonuclease
NOVO_08730	COG3335	DDE superfamily endonuclease
NOVO_08745	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NOVO_08775	COG3335	DDE superfamily endonuclease
NOVO_08780	COG3757	hydrolase, family 25
NOVO_08780	COG3409	Peptidoglycan-binding domain 1 protein
NOVO_08785	COG4695	Portal protein
NOVO_08795	COG4695	Portal protein
NOVO_08805	COG5265	(ABC) transporter
NOVO_08820	COG3335	DDE superfamily endonuclease
NOVO_08840	COG0861	Integral membrane protein TerC family
NOVO_08880	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NOVO_08895	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
NOVO_08900	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NOVO_08905	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NOVO_08910	COG0505	Belongs to the CarA family
NOVO_08920	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NOVO_08960	COG3335	DDE superfamily endonuclease
NOVO_09000	COG1338	Plays a role in the flagellum-specific transport system
NOVO_09015	COG4133	protoheme IX ABC transporter activity
NOVO_09020	COG3335	DDE superfamily endonuclease
NOVO_09080	COG1388	LysM domain
NOVO_09105	COG0489	protein tyrosine kinase activity
NOVO_09150	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NOVO_09175	COG4804	nuclease activity
NOVO_09405	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase