locus-tag	class	description
E5N89_00005	COG0460	homoserine dehydrogenase
E5N89_00005	COG0527	aspartate kinase activity
E5N89_00015	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E5N89_00025	COG1115	amino acid carrier protein
E5N89_00035	COG0521	Mo-molybdopterin cofactor biosynthetic process
E5N89_00040	COG1584	GPR1 FUN34 yaaH family protein
E5N89_00045	COG4735	regulation of single-species biofilm formation
E5N89_00100	COG3539	Fimbrial protein
E5N89_00110	COG3188	usher protein
E5N89_00125	COG3539	Fimbrial protein
E5N89_00130	COG3121	Chaperone
E5N89_00150	COG0583	DNA-binding transcription factor activity
E5N89_00165	COG0737	Belongs to the 5'-nucleotidase family
E5N89_00175	COG3119	arylsulfatase activity
E5N89_00180	COG0641	radical SAM
E5N89_00200	COG0583	DNA-binding transcription factor activity
E5N89_00225	COG0196	riboflavin kinase activity
E5N89_00240	COG1047	Peptidyl-prolyl cis-trans
E5N89_00400	COG2271	Major facilitator Superfamily
E5N89_00485	COG0417	DNA replication proofreading
E5N89_00525	COG0586	Pfam SNARE associated Golgi protein
E5N89_00535	COG1178	ABC-type Fe3 transport system permease component
E5N89_00540	COG4143	(ABC) transporter
E5N89_00595	COG1609	Transcriptional regulator
E5N89_00615	COG0768	penicillin binding
E5N89_00625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E5N89_00640	COG0772	Belongs to the SEDS family
E5N89_00665	COG0849	cell division
E5N89_00670	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E5N89_00690	COG0494	nUDIX hydrolase
E5N89_00715	COG0237	dephospho-CoA kinase activity
E5N89_00725	COG1459	type II secretion system
E5N89_00730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E5N89_00735	COG4969	Belongs to the N-Me-Phe pilin family
E5N89_00755	COG3725	Membrane protein required for beta-lactamase induction
E5N89_00760	COG3940	Belongs to the glycosyl hydrolase 43 family
E5N89_00765	COG2211	Major facilitator Superfamily
E5N89_00770	COG1113	amino acid transport
E5N89_00775	COG2186	Transcriptional regulator
E5N89_00780	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
E5N89_00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
E5N89_00790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E5N89_00805	COG3064	Membrane
E5N89_00840	COG1349	DNA-binding transcription factor activity
E5N89_00865	COG4993	Dehydrogenase
E5N89_00875	COG0288	reversible hydration of carbon dioxide
E5N89_00880	COG1131	(ABC) transporter
E5N89_00885	COG0842	Transport permease protein
E5N89_00890	COG3539	Fimbrial protein
E5N89_00910	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N89_00915	COG0726	polysaccharide deacetylase
E5N89_00935	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E5N89_00950	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E5N89_00960	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
E5N89_00965	COG1643	Atp-dependent helicase
E5N89_00970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E5N89_00975	COG4774	siderophore transport
E5N89_00980	COG1120	ATPase activity
E5N89_00985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E5N89_01005	COG3188	usher protein
E5N89_01010	COG3121	Chaperone
E5N89_01015	COG3539	Fimbrial protein
E5N89_01020	COG3539	Fimbrial protein
E5N89_01025	COG3539	Fimbrial protein
E5N89_01050	COG2860	membrane
E5N89_01075	COG3835	regulator
E5N89_01085	COG0477	Major facilitator Superfamily
E5N89_01100	COG0024	Methionine aminopeptidase
E5N89_01135	COG0575	Belongs to the CDS family
E5N89_01200	COG0346	lactoylglutathione lyase activity
E5N89_01210	COG4568	rho-dependent transcription termination
E5N89_01220	COG4681	YaeQ
E5N89_01225	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E5N89_01230	COG3015	lipoprotein NlpE involved in copper resistance
E5N89_01240	COG1720	tRNA m6t6A37 methyltransferase activity
E5N89_01305	COG0583	DNA-binding transcription factor activity
E5N89_01310	COG2814	Major facilitator Superfamily
E5N89_01320	COG2226	methyltransferase
E5N89_01325	COG1388	LysM domain
E5N89_01325	COG0741	lytic transglycosylase activity
E5N89_01335	COG2226	methyltransferase
E5N89_01345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5N89_01440	COG3047	cAMP biosynthetic process
E5N89_01440	COG2885	chlorophyll binding
E5N89_01475	COG3501	Rhs element vgr protein
E5N89_01485	COG3209	COG3209 Rhs family protein
E5N89_01495	COG3209	COG3209 Rhs family protein
E5N89_01515	COG3209	COG3209 Rhs family protein
E5N89_01585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E5N89_01600	COG0121	glutamine amidotransferase
E5N89_01605	COG3034	peptidoglycan biosynthetic process
E5N89_01620	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E5N89_01625	COG2195	Cleaves the N-terminal amino acid of tripeptides
E5N89_01670	COG0582	viral genome integration into host DNA
E5N89_01810	COG2814	Major facilitator Superfamily
E5N89_01825	COG0179	Fumarylacetoacetate (FAA) hydrolase
E5N89_01860	COG3188	usher protein
E5N89_01865	COG3121	Chaperone
E5N89_01870	COG3539	Fimbrial protein
E5N89_01885	COG2200	EAL domain
E5N89_01920	COG1538	Outer membrane efflux protein
E5N89_01930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5N89_01940	COG0789	Transcriptional regulator
E5N89_01950	COG2814	Major facilitator Superfamily
E5N89_01970	COG1271	oxidase subunit
E5N89_01975	COG1294	oxidase, subunit
E5N89_01995	COG1280	lysine exporter protein (LysE YggA)
E5N89_02030	COG0113	porphobilinogen synthase activity
E5N89_02045	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E5N89_02055	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
E5N89_02075	COG1181	Belongs to the D-alanine--D-alanine ligase family
E5N89_02100	COG3706	GGDEF domain
E5N89_02105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
E5N89_02125	COG4126	flavin adenine dinucleotide binding
E5N89_02140	COG1940	carbohydrate kinase activity
E5N89_02145	COG2814	Major facilitator Superfamily
E5N89_02150	COG0419	ATPase involved in DNA repair
E5N89_02155	COG0420	3'-5' exonuclease activity
E5N89_02165	COG5002	protein histidine kinase activity
E5N89_02170	COG1114	Component of the transport system for branched-chain amino acids
E5N89_02180	COG0366	Alpha amylase catalytic
E5N89_02185	COG0450	alkyl hydroperoxide reductase
E5N89_02205	COG1862	Preprotein translocase
E5N89_02215	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E5N89_02230	COG1403	HNH endonuclease
E5N89_02250	COG3248	Nucleoside-binding outer membrane protein
E5N89_02255	COG4238	major outer membrane lipoprotein
E5N89_02265	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E5N89_02265	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E5N89_02285	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
E5N89_02290	COG0667	Aldo Keto reductase
E5N89_02300	COG0142	geranyltranstransferase activity
E5N89_02335	COG2188	Transcriptional regulator
E5N89_02365	COG2814	Major facilitator Superfamily
E5N89_02390	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
E5N89_02395	COG1845	cytochrome c oxidase, subunit III
E5N89_02400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E5N89_02405	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E5N89_02410	COG2223	nitrite transmembrane transporter activity
E5N89_02415	COG3056	Lipoprotein
E5N89_02420	COG0271	Belongs to the BolA IbaG family
E5N89_02445	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
E5N89_02450	COG0776	regulation of translation
E5N89_02455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E5N89_02460	COG1555	photosystem II stabilization
E5N89_02465	COG0824	Thioesterase
E5N89_02475	COG4533	DNA binding
E5N89_02485	COG1943	Transposase
E5N89_02495	COG1522	sequence-specific DNA binding
E5N89_02500	COG1132	(ABC) transporter
E5N89_02505	COG1132	(ABC) transporter
E5N89_02515	COG0347	Belongs to the P(II) protein family
E5N89_02520	COG0004	ammonium transporteR
E5N89_02525	COG1946	Acyl-CoA thioesterase
E5N89_02530	COG3126	Type III secretion system lipoprotein chaperone (YscW)
E5N89_02535	COG3695	enzyme binding
E5N89_02545	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E5N89_02565	COG0110	maltose O-acetyltransferase activity
E5N89_02580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5N89_02585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5N89_02590	COG1309	transcriptional regulator
E5N89_02595	COG1196	nuclear chromosome segregation
E5N89_02595	COG3264	Mechanosensitive ion channel
E5N89_02600	COG5464	transposase or invertase
E5N89_02610	COG3923	Primosomal replication protein n
E5N89_02615	COG2832	Protein of unknown function (DUF454)
E5N89_02660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5N89_02665	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E5N89_02665	COG4651	solute:proton antiporter activity
E5N89_02670	COG2223	nitrite transmembrane transporter activity
E5N89_02685	COG3735	TraB family
E5N89_02705	COG1585	Membrane protein implicated in regulation of membrane protease activity
E5N89_02710	COG0330	HflC and HflK could
E5N89_02715	COG4619	ABC transporter
E5N89_02720	COG0390	transport system, permease component
E5N89_02725	COG3118	belongs to the thioredoxin family
E5N89_02730	COG0300	oxidoreductase activity
E5N89_02735	COG2755	lipolytic protein G-D-S-L family
E5N89_02740	COG4181	ATPase activity
E5N89_02745	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
E5N89_02755	COG1464	Belongs to the NlpA lipoprotein family
E5N89_02790	COG3960	tartronate-semialdehyde synthase activity
E5N89_02795	COG3622	Belongs to the hyi family
E5N89_02800	COG2084	Dehydrogenase
E5N89_02810	COG1953	Uracil, thiamine, allantoin
E5N89_02820	COG2233	PERMEase
E5N89_02825	COG1929	Belongs to the glycerate kinase type-1 family
E5N89_02830	COG3257	ureidoglycine aminohydrolase activity
E5N89_02835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E5N89_02840	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E5N89_02845	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E5N89_02850	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E5N89_02860	COG0549	Belongs to the carbamate kinase family
E5N89_02865	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
E5N89_02870	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E5N89_02880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
E5N89_02900	COG1988	membrane-bound metal-dependent
E5N89_02905	COG2501	S4 domain
E5N89_02975	COG0582	viral genome integration into host DNA
E5N89_02990	COG0463	Glycosyl transferase, family 2
E5N89_02995	COG2246	polysaccharide biosynthetic process
E5N89_03005	COG5002	protein histidine kinase activity
E5N89_03010	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5N89_03015	COG2207	Transcriptional regulator
E5N89_03020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E5N89_03030	COG3059	membrane
E5N89_03040	COG1113	amino acid transport
E5N89_03045	COG0668	transmembrane transport
E5N89_03055	COG3933	PFAM sigma-54 factor interaction domain-containing protein
E5N89_03055	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
E5N89_03060	COG2222	sugar isomerase
E5N89_03070	COG3716	PTS system mannose fructose sorbose family IID component
E5N89_03095	COG2315	Protein conserved in bacteria
E5N89_03125	COG4771	TonB-dependent receptor
E5N89_03130	COG2382	esterase
E5N89_03135	COG3251	PFAM MbtH domain protein
E5N89_03140	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
E5N89_03140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E5N89_03145	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
E5N89_03150	COG1120	ATPase activity
E5N89_03155	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E5N89_03160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E5N89_03170	COG4592	Periplasmic binding protein
E5N89_03175	COG1169	isochorismate synthase
E5N89_03180	COG1021	2,3-dihydroxybenzoate-AMP ligase
E5N89_03185	COG3433	isochorismatase activity
E5N89_03185	COG1535	isochorismatase
E5N89_03190	COG1028	Short-chain dehydrogenase reductase Sdr
E5N89_03200	COG1966	Carbon starvation protein
E5N89_03205	COG2879	small protein
E5N89_03210	COG0371	Dehydrogenase
E5N89_03215	COG0436	Aminotransferase
E5N89_03220	COG1475	DNA binding
E5N89_03225	COG3969	phosphoadenosine phosphosulfate
E5N89_03230	COG0583	DNA-binding transcription factor activity
E5N89_03235	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E5N89_03240	COG0450	alkyl hydroperoxide reductase
E5N89_03255	COG0243	molybdopterin cofactor binding
E5N89_03270	COG0589	response to stress
E5N89_03275	COG1063	alcohol dehydrogenase
E5N89_03280	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E5N89_03285	COG3719	Belongs to the RNase T2 family
E5N89_03290	COG0471	metal ion transport
E5N89_03305	COG3051	citrate lyase alpha subunit
E5N89_03310	COG2301	Belongs to the HpcH HpaI aldolase family
E5N89_03315	COG3052	prosthetic group binding
E5N89_03320	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
E5N89_03325	COG3290	protein histidine kinase activity
E5N89_03330	COG4565	transcriptional regulatory protein
E5N89_03335	COG3069	C4-dicarboxylate transmembrane transporter activity
E5N89_03345	COG1278	Cold shock
E5N89_03355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E5N89_03370	COG0583	DNA-binding transcription factor activity
E5N89_03385	COG1686	Belongs to the peptidase S11 family
E5N89_03395	COG0772	Belongs to the SEDS family
E5N89_03400	COG0768	penicillin binding
E5N89_03410	COG0799	negative regulation of ribosome biogenesis
E5N89_03430	COG1466	dna polymerase III delta subunit
E5N89_03460	COG3829	transcription factor binding
E5N89_03460	COG3290	protein histidine kinase activity
E5N89_03465	COG2888	peptidyl-tyrosine sulfation
E5N89_03480	COG2214	Heat shock protein DnaJ domain protein
E5N89_03490	COG2214	Heat shock protein DnaJ domain protein
E5N89_03495	COG0443	Heat shock 70 kDa protein
E5N89_03510	COG1126	abc transporter atp-binding protein
E5N89_03515	COG0765	amino acid transport
E5N89_03520	COG0765	amino acid transport
E5N89_03535	COG4535	Mg2 and Co2 transporter CorC
E5N89_03545	COG1702	phosphate starvation-inducible protein PhoH
E5N89_03555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E5N89_03600	COG0367	asparagine synthase
E5N89_03605	COG0647	UMP catabolic process
E5N89_03610	COG1846	Transcriptional regulator
E5N89_03610	COG1940	carbohydrate kinase activity
E5N89_03615	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E5N89_03645	COG0477	Major facilitator Superfamily
E5N89_03655	COG1053	succinate dehydrogenase
E5N89_03660	COG0583	DNA-binding transcription factor activity
E5N89_03665	COG0735	belongs to the Fur family
E5N89_03680	COG0596	Alpha beta hydrolase
E5N89_03690	COG0033	Phosphoglucomutase
E5N89_03700	COG0531	amino acid
E5N89_03705	COG1982	Orn Lys Arg decarboxylase major
E5N89_03715	COG0745	RESPONSE REGULATOR receiver
E5N89_03720	COG2205	protein histidine kinase activity
E5N89_03760	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
E5N89_03765	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E5N89_03770	COG1984	allophanate hydrolase subunit 2
E5N89_03785	COG0582	viral genome integration into host DNA
E5N89_03825	COG1216	Glycosyl transferase, family 2
E5N89_03850	COG3180	Ammonia monooxygenase
E5N89_03860	COG2009	succinate dehydrogenase
E5N89_03865	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
E5N89_03880	COG0567	Dehydrogenase, E1 component
E5N89_03885	COG0508	dehydrogenase complex catalyzes the overall conversion of
E5N89_03895	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E5N89_03900	COG1271	oxidase subunit
E5N89_03905	COG1294	oxidase, subunit
E5N89_03910	COG4890	Cyd operon protein YbgT
E5N89_03915	COG3790	cyd operon protein YbgE
E5N89_03920	COG0824	Thioesterase
E5N89_03925	COG0811	peptide transport
E5N89_03930	COG0848	biopolymer transport protein
E5N89_03935	COG3064	Membrane
E5N89_03945	COG2885	chlorophyll binding
E5N89_03950	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
E5N89_04010	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E5N89_04015	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E5N89_04015	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E5N89_04020	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E5N89_04025	COG0583	DNA-binding transcription factor activity
E5N89_04030	COG0583	DNA-binding transcription factor activity
E5N89_04035	COG0471	metal ion transport
E5N89_04035	COG0490	domain, Protein
E5N89_04060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E5N89_04065	COG1120	ATPase activity
E5N89_04075	COG2017	converts alpha-aldose to the beta-anomer
E5N89_04100	COG1119	ATPase activity
E5N89_04105	COG3585	molybdate ion transport
E5N89_04105	COG2005	Transcriptional regulator
E5N89_04115	COG0725	ABC transporter, periplasmic molybdate-binding protein
E5N89_04120	COG4149	molybdate abc transporter
E5N89_04130	COG0561	phosphatase activity
E5N89_04140	COG4677	pectinesterase activity
E5N89_04170	COG1881	PFAM PEBP family protein
E5N89_04230	COG0521	Mo-molybdopterin cofactor biosynthetic process
E5N89_04240	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
E5N89_04245	COG0314	molybdopterin synthase activity
E5N89_04250	COG0670	Belongs to the BI1 family
E5N89_04255	COG1943	Transposase
E5N89_04280	COG0392	lysyltransferase activity
E5N89_04290	COG3568	Endonuclease Exonuclease Phosphatase
E5N89_04300	COG0842	Transport permease protein
E5N89_04305	COG0842	Transport permease protein
E5N89_04310	COG1131	(ABC) transporter
E5N89_04320	COG1309	transcriptional regulator
E5N89_04325	COG0513	Belongs to the DEAD box helicase family
E5N89_04335	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E5N89_04345	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E5N89_04355	COG0668	transmembrane transport
E5N89_04360	COG1126	abc transporter atp-binding protein
E5N89_04365	COG0765	amino acid transport
E5N89_04370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5N89_04385	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
E5N89_04390	COG2194	sulfuric ester hydrolase activity
E5N89_04400	COG1321	iron dependent repressor
E5N89_04405	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E5N89_04410	COG1376	ErfK ybiS ycfS ynhG family protein
E5N89_04415	COG0488	(ABC) transporter
E5N89_04435	COG0561	phosphatase activity
E5N89_04445	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E5N89_04495	COG2301	Belongs to the HpcH HpaI aldolase family
E5N89_04515	COG1960	acyl-CoA dehydrogenase activity
E5N89_04530	COG0583	DNA-binding transcription factor activity
E5N89_04535	COG2610	gluconate transmembrane transporter activity
E5N89_04540	COG2133	pyrroloquinoline quinone binding
E5N89_04545	COG0625	glutathione transferase activity
E5N89_04550	COG1686	Belongs to the peptidase S11 family
E5N89_04555	COG1349	DNA-binding transcription factor activity
E5N89_04560	COG0671	phosphoesterase, PA-phosphatase related
E5N89_04565	COG2814	Major facilitator Superfamily
E5N89_04570	COG0561	phosphatase activity
E5N89_04575	COG0738	Major facilitator superfamily
E5N89_04580	COG3226	Transcriptional regulator
E5N89_04600	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E5N89_04625	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E5N89_04630	COG3842	ATPase activity
E5N89_04635	COG1176	ABC-type spermidine putrescine transport system, permease component I
E5N89_04640	COG1177	transmembrane transport
E5N89_04670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5N89_04675	COG4160	amino acid transport
E5N89_04680	COG4215	(ABC) transporter
E5N89_04685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5N89_04690	COG1126	abc transporter atp-binding protein
E5N89_04705	COG3023	N-Acetylmuramoyl-L-alanine amidase
E5N89_04710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E5N89_04715	COG0702	epimerase
E5N89_04720	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
E5N89_04725	COG0028	Belongs to the TPP enzyme family
E5N89_04730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E5N89_04740	COG2431	L-lysine efflux transmembrane transporter activity
E5N89_04745	COG3593	DNA synthesis involved in DNA repair
E5N89_04750	COG2990	Protein conserved in bacteria
E5N89_04755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5N89_04765	COG1278	Cold shock
E5N89_04775	COG0542	response to heat
E5N89_04780	COG1943	Transposase
E5N89_04800	COG1335	isochorismatase
E5N89_04810	COG0583	DNA-binding transcription factor activity
E5N89_04830	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E5N89_04835	COG4988	ABC transporter
E5N89_04840	COG0492	ferredoxin-NADP+ reductase activity
E5N89_04860	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E5N89_04870	COG0243	molybdopterin cofactor binding
E5N89_04875	COG0437	4 iron, 4 sulfur cluster binding
E5N89_04880	COG3302	dmso reductase anchor subunit
E5N89_04890	COG0531	amino acid
E5N89_04895	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E5N89_04910	COG1882	Formate acetyltransferase
E5N89_04915	COG2116	formate transmembrane transporter activity
E5N89_04920	COG1944	ATP diphosphatase activity
E5N89_04925	COG2323	membrane
E5N89_04940	COG0501	Belongs to the peptidase M48B family
E5N89_04950	COG0539	negative regulation of cytoplasmic translation
E5N89_04960	COG0658	competence protein
E5N89_04960	COG2333	competence protein COMEC
E5N89_04975	COG3214	Protein conserved in bacteria
E5N89_04995	COG3173	Aminoglycoside phosphotransferase
E5N89_05000	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E5N89_05005	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E5N89_05015	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
E5N89_05025	COG2989	Protein conserved in bacteria
E5N89_05030	COG3108	Peptidase M15
E5N89_05035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E5N89_05055	COG1522	sequence-specific DNA binding
E5N89_05070	COG1115	amino acid carrier protein
E5N89_05080	COG0582	viral genome integration into host DNA
E5N89_05100	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5N89_05135	COG1484	DNA-dependent DNA replication
E5N89_05240	COG4220	transposase activity
E5N89_05295	COG5301	cellulose 1,4-beta-cellobiosidase activity
E5N89_05320	COG2135	peptidase activity
E5N89_05340	COG0308	aminopeptidase N
E5N89_05355	COG3217	Mosc domain protein beta barrel domain protein
E5N89_05355	COG0633	Ferredoxin
E5N89_05365	COG0488	(ABC) transporter
E5N89_05370	COG2995	paraquat-inducible protein a
E5N89_05375	COG3008	intermembrane lipid transfer
E5N89_05375	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E5N89_05380	COG3009	Protein conserved in bacteria
E5N89_05385	COG3130	regulation of translation
E5N89_05395	COG1067	ATP-dependent peptidase activity
E5N89_05415	COG3070	regulator of competence-specific genes
E5N89_05420	COG1289	transmembrane transporter activity
E5N89_05425	COG3304	Inner membrane component domain
E5N89_05430	COG0210	DNA helicase
E5N89_05445	COG1832	CoA-binding protein
E5N89_05460	COG1881	PFAM PEBP family protein
E5N89_05470	COG1254	Belongs to the acylphosphatase family
E5N89_05480	COG0670	Belongs to the BI1 family
E5N89_05530	COG2205	protein histidine kinase activity
E5N89_05535	COG0745	RESPONSE REGULATOR receiver
E5N89_05550	COG2368	4-hydroxyphenylacetate
E5N89_05555	COG1846	Transcriptional regulator
E5N89_05565	COG1012	belongs to the aldehyde dehydrogenase family
E5N89_05570	COG3384	dioxygenase
E5N89_05580	COG3971	2-oxopent-4-enoate hydratase activity
E5N89_05630	COG4232	protein-disulfide reductase activity
E5N89_05635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E5N89_05635	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E5N89_05640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E5N89_05660	COG3729	General stress protein
E5N89_05665	COG1309	transcriptional regulator
E5N89_05685	COG1702	phosphate starvation-inducible protein PhoH
E5N89_05690	COG1737	Transcriptional regulator
E5N89_05695	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E5N89_05710	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
E5N89_05715	COG2814	Major facilitator Superfamily
E5N89_05720	COG0673	inositol 2-dehydrogenase activity
E5N89_05755	COG3381	protein complex oligomerization
E5N89_05765	COG1462	curli production assembly transport component CsgG
E5N89_05805	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
E5N89_05810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E5N89_05835	COG5645	(Lipo)protein
E5N89_05850	COG1560	Kdo2-lipid A biosynthetic process
E5N89_05865	COG3038	cytochrome b561
E5N89_05900	COG2999	glutathione oxidoreductase activity
E5N89_05910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E5N89_05930	COG3418	PFAM FlgN family protein
E5N89_05950	COG1558	bacterial-type flagellum-dependent cell motility
E5N89_05955	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
E5N89_05960	COG1749	Flagellar hook protein flgE
E5N89_05970	COG4786	Flagellar basal body rod
E5N89_05990	COG1256	bacterial-type flagellum assembly
E5N89_06000	COG1530	ribonuclease E activity
E5N89_06030	COG1399	metal-binding, possibly nucleic acid-binding protein
E5N89_06055	COG1028	Short-chain dehydrogenase reductase Sdr
E5N89_06065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E5N89_06070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E5N89_06075	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
E5N89_06085	COG0470	DNA polymerase III
E5N89_06090	COG0084	hydrolase, TatD family'
E5N89_06100	COG4773	Receptor
E5N89_06105	COG0537	adenosine 5'-monophosphoramidase activity
E5N89_06110	COG5633	Lipoprotein
E5N89_06135	COG1252	NADH dehydrogenase
E5N89_06140	COG3134	Outer membrane lipoprotein
E5N89_06145	COG1309	transcriptional regulator
E5N89_06155	COG1376	ErfK ybiS ycfS ynhG family protein
E5N89_06155	COG1388	LysM domain
E5N89_06160	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
E5N89_06165	COG4591	ABC-type transport system involved in lipoprotein release permease component
E5N89_06175	COG4591	ABC-type transport system involved in lipoprotein release permease component
E5N89_06185	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
E5N89_06190	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E5N89_06195	COG1177	transmembrane transport
E5N89_06205	COG1176	ABC-type spermidine putrescine transport system, permease component I
E5N89_06225	COG2850	peptidyl-arginine hydroxylation
E5N89_06240	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
E5N89_06270	COG0538	isocitrate dehydrogenase activity
E5N89_06300	COG1278	Cold shock
E5N89_06340	COG0071	Belongs to the small heat shock protein (HSP20) family
E5N89_06350	COG3038	cytochrome b561
E5N89_06380	COG1124	(ABC) transporter
E5N89_06385	COG0668	transmembrane transport
E5N89_06400	COG3443	Belongs to the bacterial solute-binding protein 9 family
E5N89_06415	COG0789	Transcriptional regulator
E5N89_06430	COG1605	Chorismate mutase
E5N89_06440	COG3615	Tellurite resistance protein tehB
E5N89_06460	COG2261	transglycosylase associated protein
E5N89_06470	COG3042	response to heat
E5N89_06480	COG3189	MarR family transcriptional regulator
E5N89_06485	COG2807	transmembrane transport
E5N89_06490	COG2207	Transcriptional regulator
E5N89_06505	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E5N89_06510	COG2199	diguanylate cyclase activity
E5N89_06525	COG2766	serine protein kinase
E5N89_06530	COG3713	MltA-interacting MipA family protein
E5N89_06535	COG0641	radical SAM
E5N89_06540	COG0656	L-ascorbic acid biosynthetic process
E5N89_06550	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
E5N89_06560	COG3139	Protein of unknown function (DUF1315)
E5N89_06565	COG1335	isochorismatase
E5N89_06570	COG0252	asparaginase activity
E5N89_06575	COG0616	signal peptide processing
E5N89_06580	COG0778	Nitroreductase
E5N89_06605	COG0494	nUDIX hydrolase
E5N89_06610	COG0708	Exodeoxyribonuclease III
E5N89_06640	COG3678	ATP-independent chaperone mediated protein folding
E5N89_06655	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5N89_06665	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E5N89_06670	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E5N89_06675	COG1447	Phosphotransferase system cellobiose-specific component IIA
E5N89_06680	COG2169	Transcriptional regulator
E5N89_06680	COG1917	Cupin 2, conserved barrel domain protein
E5N89_06685	COG1486	melibiose metabolic process
E5N89_06695	COG0753	catalase activity
E5N89_06710	COG1988	membrane-bound metal-dependent
E5N89_06715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E5N89_06735	COG1105	Belongs to the carbohydrate kinase PfkB family
E5N89_06740	COG3137	Salt-induced outer membrane protein
E5N89_06820	COG0386	Belongs to the glutathione peroxidase family
E5N89_06830	COG0791	NLP P60 protein
E5N89_06845	COG4256	Hemin uptake protein
E5N89_06860	COG0574	Belongs to the PEP-utilizing enzyme family
E5N89_06860	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E5N89_06865	COG0318	PFAM AMP-dependent synthetase and ligase
E5N89_06870	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
E5N89_06875	COG0644	oxidoreductase
E5N89_06880	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
E5N89_06885	COG2086	electron transfer activity
E5N89_06890	COG2207	Transcriptional regulator
E5N89_06890	COG1917	Cupin 2, conserved barrel domain protein
E5N89_06895	COG1960	acyl-CoA dehydrogenase activity
E5N89_06900	COG4670	ketone body catabolic process
E5N89_06915	COG2271	Major facilitator Superfamily
E5N89_06920	COG0738	Major facilitator superfamily
E5N89_06935	COG0628	permease
E5N89_06940	COG0277	FAD linked oxidase domain protein
E5N89_06940	COG0247	lactate metabolic process
E5N89_06945	COG2050	protein possibly involved in aromatic compounds catabolism
E5N89_06960	COG0316	Belongs to the HesB IscA family
E5N89_06965	COG0719	Fe-S assembly protein
E5N89_06970	COG0396	ATPase activity
E5N89_06975	COG0719	Fe-S assembly protein
E5N89_06990	COG1376	ErfK ybiS ycfS ynhG family protein
E5N89_07010	COG0531	amino acid
E5N89_07015	COG2267	carboxylic ester hydrolase activity
E5N89_07025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5N89_07060	COG3272	Protein of unknown function (DUF1722)
E5N89_07065	COG0789	Transcriptional regulator
E5N89_07245	COG0307	riboflavin synthase, alpha
E5N89_07250	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E5N89_07255	COG2814	Major facilitator Superfamily
E5N89_07260	COG0583	DNA-binding transcription factor activity
E5N89_07275	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
E5N89_07280	COG0791	NLP P60 protein
E5N89_07285	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
E5N89_07300	COG0346	lactoylglutathione lyase activity
E5N89_07305	COG1902	pentaerythritol trinitrate reductase activity
E5N89_07310	COG1309	transcriptional regulator
E5N89_07315	COG3313	Fe-S protein
E5N89_07320	COG4989	oxidoreductase activity
E5N89_07335	COG1566	PFAM secretion protein HlyD family protein
E5N89_07350	COG3133	Outer membrane lipoprotein
E5N89_07360	COG3895	Periplasmic Protein
E5N89_07380	COG0625	glutathione transferase activity
E5N89_07390	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E5N89_07440	COG0673	inositol 2-dehydrogenase activity
E5N89_07455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5N89_07455	COG1263	PTS System
E5N89_07460	COG5339	Protein conserved in bacteria
E5N89_07485	COG2205	protein histidine kinase activity
E5N89_07490	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
E5N89_07495	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E5N89_07505	COG0745	RESPONSE REGULATOR receiver
E5N89_07510	COG3136	membrane protein required for alginate biosynthesis
E5N89_07515	COG0531	amino acid
E5N89_07525	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
E5N89_07530	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
E5N89_07535	COG0628	permease
E5N89_07555	COG3591	Belongs to the peptidase S1B family
E5N89_07565	COG2814	Major facilitator Superfamily
E5N89_07570	COG0583	DNA-binding transcription factor activity
E5N89_07575	COG1940	carbohydrate kinase activity
E5N89_07615	COG3302	dmso reductase anchor subunit
E5N89_07620	COG0437	4 iron, 4 sulfur cluster binding
E5N89_07625	COG0243	molybdopterin cofactor binding
E5N89_07630	COG0243	molybdopterin cofactor binding
E5N89_07645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E5N89_07665	COG1063	alcohol dehydrogenase
E5N89_07670	COG0477	Major facilitator Superfamily
E5N89_07675	COG0477	Major facilitator Superfamily
E5N89_07680	COG0246	Mannitol dehydrogenase
E5N89_07690	COG1802	Transcriptional regulator
E5N89_07695	COG4221	oxidoreductase activity
E5N89_07710	COG3729	General stress protein
E5N89_07715	COG1546	Belongs to the CinA family
E5N89_07720	COG3111	PFAM Bacterial OB fold (BOF) protein
E5N89_07730	COG2814	Major facilitator Superfamily
E5N89_07750	COG1846	Transcriptional regulator
E5N89_07770	COG0583	DNA-binding transcription factor activity
E5N89_07775	COG1012	belongs to the aldehyde dehydrogenase family
E5N89_07790	COG3781	membrane
E5N89_07815	COG1773	rubredoxin
E5N89_07840	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
E5N89_07845	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E5N89_07855	COG2186	Transcriptional regulator
E5N89_07860	COG1063	alcohol dehydrogenase
E5N89_07865	COG2271	Major facilitator Superfamily
E5N89_07880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E5N89_07890	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
E5N89_07895	COG0251	oxidation-reduction process
E5N89_07945	COG1609	Transcriptional regulator
E5N89_07950	COG1757	Na H antiporter
E5N89_07955	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
E5N89_07970	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
E5N89_07985	COG1764	response to oxidative stress
E5N89_08005	COG1064	alcohol dehydrogenase
E5N89_08010	COG2864	formate dehydrogenase
E5N89_08015	COG0437	4 iron, 4 sulfur cluster binding
E5N89_08055	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E5N89_08060	COG1140	nitrate reductase beta subunit
E5N89_08065	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E5N89_08070	COG2181	nitrate reductase activity
E5N89_08110	COG4772	TonB-dependent receptor
E5N89_08115	COG1802	Transcriptional regulator
E5N89_08120	COG2130	NADP-dependent
E5N89_08130	COG3238	Protein conserved in bacteria
E5N89_08170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E5N89_08175	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
E5N89_08200	COG0826	peptidase U32
E5N89_08205	COG1396	sequence-specific DNA binding
E5N89_08210	COG3135	benzoate transporter
E5N89_08220	COG0500	methyltransferase
E5N89_08225	COG1275	C4-dicarboxylate transporter malic acid transport protein
E5N89_08230	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E5N89_08235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E5N89_08245	COG3414	Phosphotransferase system galactitol-specific IIB component
E5N89_08250	COG3775	system Galactitol-specific IIC component
E5N89_08255	COG0434	BtpA family
E5N89_08260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N89_08265	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E5N89_08270	COG1349	DNA-binding transcription factor activity
E5N89_08280	COG1304	FMN binding
E5N89_08285	COG2353	YceI-like domain
E5N89_08295	COG2272	Belongs to the type-B carboxylesterase lipase family
E5N89_08300	COG5383	Protein conserved in bacteria
E5N89_08305	COG0583	DNA-binding transcription factor activity
E5N89_08310	COG0840	transmembrane signaling receptor activity
E5N89_08345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5N89_08350	COG0765	amino acid transport
E5N89_08360	COG0765	amino acid transport
E5N89_08370	COG0500	methyltransferase
E5N89_08375	COG3038	cytochrome b561
E5N89_08380	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E5N89_08385	COG1643	Atp-dependent helicase
E5N89_08400	COG3784	Protein of unknown function (DUF1318)
E5N89_08410	COG2911	Protein conserved in bacteria
E5N89_08415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E5N89_08420	COG3187	Heat shock protein
E5N89_08425	COG3042	response to heat
E5N89_08435	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E5N89_08435	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E5N89_08435	COG0674	pyruvate-flavodoxin oxidoreductase activity
E5N89_08435	COG1013	pyruvate-flavodoxin oxidoreductase activity
E5N89_08440	COG0589	response to stress
E5N89_08445	COG2076	Multidrug Resistance protein
E5N89_08465	COG0513	Belongs to the DEAD box helicase family
E5N89_08480	COG0840	transmembrane signaling receptor activity
E5N89_08485	COG2840	Smr protein MutS2
E5N89_08490	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E5N89_08505	COG3182	Iron-regulated membrane protein
E5N89_08510	COG0668	transmembrane transport
E5N89_08530	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
E5N89_08565	COG1309	transcriptional regulator
E5N89_08570	COG1028	Short-chain dehydrogenase reductase Sdr
E5N89_08575	COG0656	L-ascorbic acid biosynthetic process
E5N89_08580	COG0583	DNA-binding transcription factor activity
E5N89_08590	COG4166	transmembrane transport
E5N89_08595	COG2866	Carboxypeptidase
E5N89_08600	COG4948	Mandelate Racemase Muconate Lactonizing
E5N89_08610	COG3283	Transcriptional regulator of aromatic amino acids metabolism
E5N89_08620	COG3106	COG3106 Predicted ATPase
E5N89_08625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E5N89_08635	COG1983	PspC domain protein
E5N89_08645	COG1842	Phage shock protein A
E5N89_08650	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
E5N89_08660	COG4168	peptide transport system, permease
E5N89_08665	COG4171	peptide transport system, permease
E5N89_08705	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E5N89_08705	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E5N89_08715	COG5001	Diguanylate cyclase
E5N89_08725	COG1349	DNA-binding transcription factor activity
E5N89_08735	COG0023	Translation Initiation Factor
E5N89_08745	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
E5N89_08750	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
E5N89_08755	COG0671	phosphoesterase, PA-phosphatase related
E5N89_08785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E5N89_08795	COG0616	signal peptide processing
E5N89_08800	COG1028	Short-chain dehydrogenase reductase Sdr
E5N89_08815	COG0009	L-threonylcarbamoyladenylate synthase
E5N89_08855	COG3729	General stress protein
E5N89_08860	COG3685	Protein conserved in bacteria
E5N89_08865	COG3685	Protein conserved in bacteria
E5N89_08870	COG3546	catalase activity
E5N89_08895	COG1607	acyl-coa hydrolase
E5N89_08905	COG2350	Protein conserved in bacteria
E5N89_08925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E5N89_08955	COG2095	MarC family integral membrane protein
E5N89_08960	COG1012	belongs to the aldehyde dehydrogenase family
E5N89_08960	COG1454	alcohol dehydrogenase
E5N89_08975	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E5N89_08980	COG0745	RESPONSE REGULATOR receiver
E5N89_08985	COG1752	Esterase of the alpha-beta hydrolase superfamily
E5N89_08995	COG0788	formyltetrahydrofolate deformylase activity
E5N89_09040	COG2181	nitrate reductase activity
E5N89_09045	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E5N89_09050	COG1140	nitrate reductase beta subunit
E5N89_09055	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E5N89_09060	COG2223	nitrite transmembrane transporter activity
E5N89_09065	COG3850	Histidine kinase
E5N89_09070	COG2197	response regulator
E5N89_09075	COG4932	domain protein
E5N89_09080	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
E5N89_09085	COG4572	Cation transport regulator
E5N89_09090	COG0387	Pfam Sodium calcium exchanger
E5N89_09100	COG2912	Transglutaminase-like superfamily
E5N89_09105	COG3094	Invasion gene expression up-regulator, SirB
E5N89_09135	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
E5N89_09140	COG0659	secondary active sulfate transmembrane transporter activity
E5N89_09155	COG0012	GTP binding
E5N89_09165	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E5N89_09175	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
E5N89_09180	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E5N89_09185	COG1999	signal sequence binding
E5N89_09190	COG1773	rubredoxin
E5N89_09195	COG1271	oxidase subunit
E5N89_09200	COG1294	oxidase, subunit
E5N89_09210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
E5N89_09235	COG1619	proteins homologs of microcin C7 resistance protein MccF
E5N89_09255	COG2719	SpoVR family
E5N89_09295	COG0179	Fumarylacetoacetate (FAA) hydrolase
E5N89_09310	COG2894	cell division
E5N89_09320	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
E5N89_09325	COG0318	PFAM AMP-dependent synthetase and ligase
E5N89_09330	COG3065	identical protein binding
E5N89_09340	COG1199	ATP-dependent helicase activity
E5N89_09345	COG0251	oxidation-reduction process
E5N89_09365	COG1760	l-serine dehydratase
E5N89_09370	COG2200	EAL domain
E5N89_09375	COG1253	flavin adenine dinucleotide binding
E5N89_09380	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N89_09380	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5N89_09385	COG3715	PTS system
E5N89_09390	COG3716	PTS system mannose fructose sorbose family IID component
E5N89_09405	COG2226	methyltransferase
E5N89_09410	COG0768	penicillin binding
E5N89_09415	COG1278	Cold shock
E5N89_09440	COG1414	Transcriptional regulator
E5N89_09445	COG2814	Major facilitator Superfamily
E5N89_09465	COG1956	GAF domain-containing protein
E5N89_09470	COG2995	paraquat-inducible protein a
E5N89_09475	COG3008	intermembrane lipid transfer
E5N89_09510	COG5562	phage envelope protein
E5N89_09520	COG0454	-acetyltransferase
E5N89_09625	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5N89_09640	COG1276	copper resistance
E5N89_09645	COG2372	response to copper ion
E5N89_09655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E5N89_09660	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5N89_09665	COG1770	oligopeptidase
E5N89_09670	COG2979	Protein of unknown function (DUF533)
E5N89_09680	COG3141	response to X-ray
E5N89_09690	COG0800	Aldolase
E5N89_09695	COG0129	dihydroxy-acid dehydratase activity
E5N89_09700	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E5N89_09705	COG1737	Transcriptional regulator
E5N89_09715	COG1560	Kdo2-lipid A biosynthetic process
E5N89_09720	COG0739	heme binding
E5N89_09725	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
E5N89_09735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E5N89_09770	COG0494	nUDIX hydrolase
E5N89_09780	COG1335	isochorismatase
E5N89_09785	COG1801	Protein of unknown function DUF72
E5N89_09790	COG3788	relative of glutathione S-transferase, MAPEG superfamily
E5N89_09810	COG3102	Protein conserved in bacteria
E5N89_09825	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
E5N89_09850	COG0745	RESPONSE REGULATOR receiver
E5N89_09930	COG1528	Iron-storage protein
E5N89_09945	COG1528	Iron-storage protein
E5N89_09955	COG0814	amino acid
E5N89_09960	COG3318	Belongs to the UPF0149 family
E5N89_09960	COG3012	SEC-C Motif Domain Protein
E5N89_10005	COG2197	response regulator
E5N89_10020	COG2197	response regulator
E5N89_10050	COG1191	sigma factor activity
E5N89_10055	COG1943	Transposase
E5N89_10100	COG0425	Belongs to the sulfur carrier protein TusA family
E5N89_10120	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E5N89_10135	COG2882	bacterial-type flagellum organization
E5N89_10160	COG3190	flagellar
E5N89_10170	COG1987	bacterial-type flagellum assembly
E5N89_10205	COG5475	Uncharacterized small protein (DUF2158)
E5N89_10210	COG2354	Protein conserved in bacteria
E5N89_10215	COG0697	spore germination
E5N89_10220	COG3727	T/G mismatch-specific endonuclease activity
E5N89_10225	COG0270	DNA (cytosine-5-)-methyltransferase activity
E5N89_10230	COG1418	mRNA catabolic process
E5N89_10240	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E5N89_10315	COG3778	Protein conserved in bacteria
E5N89_10320	COG3299	homolog of phage Mu protein gp47
E5N89_10365	COG4386	tail sheath protein
E5N89_10410	COG4695	Portal protein
E5N89_10420	COG1802	Transcriptional regulator
E5N89_10420	COG4626	Terminase
E5N89_10450	COG3179	chitinase
E5N89_10475	COG0484	heat shock protein binding
E5N89_10480	COG1403	HNH endonuclease
E5N89_10490	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
E5N89_10495	COG0338	D12 class N6 adenine-specific DNA methyltransferase
E5N89_10515	COG3646	Phage regulatory protein
E5N89_10555	COG5532	Uncharacterized conserved protein (DUF2303)
E5N89_10560	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
E5N89_10610	COG0582	viral genome integration into host DNA
E5N89_10665	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
E5N89_10690	COG0534	Mate efflux family protein
E5N89_10770	COG2875	Belongs to the precorrin methyltransferase family
E5N89_10780	COG2241	protein methyltransferase activity
E5N89_10815	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
E5N89_10850	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
E5N89_10855	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
E5N89_10885	COG1012	belongs to the aldehyde dehydrogenase family
E5N89_10885	COG1454	alcohol dehydrogenase
E5N89_10890	COG4656	Part of a membrane complex involved in electron transport
E5N89_10900	COG4810	utilization protein
E5N89_10925	COG1289	transmembrane transporter activity
E5N89_10930	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E5N89_10945	COG0437	4 iron, 4 sulfur cluster binding
E5N89_10965	COG2925	Exonuclease
E5N89_10970	COG0531	amino acid
E5N89_10980	COG0583	DNA-binding transcription factor activity
E5N89_10985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E5N89_11130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E5N89_11145	COG2327	Polysaccharide pyruvyl transferase
E5N89_11150	COG2244	polysaccharide biosynthetic process
E5N89_11155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E5N89_11170	COG0297	glycogen (starch) synthase activity
E5N89_11180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E5N89_11185	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
E5N89_11190	COG0110	maltose O-acetyltransferase activity
E5N89_11195	COG1216	Glycosyl transferase, family 2
E5N89_11205	COG0438	transferase activity, transferring glycosyl groups
E5N89_11210	COG1045	serine acetyltransferase
E5N89_11215	COG0463	Glycosyl transferase, family 2
E5N89_11235	COG1253	flavin adenine dinucleotide binding
E5N89_11240	COG2982	Protein involved in outer membrane biogenesis
E5N89_11255	COG5001	Diguanylate cyclase
E5N89_11255	COG3447	MASE1 domain protein
E5N89_11255	COG5002	protein histidine kinase activity
E5N89_11260	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
E5N89_11265	COG0443	Heat shock 70 kDa protein
E5N89_11295	COG2205	protein histidine kinase activity
E5N89_11300	COG0745	RESPONSE REGULATOR receiver
E5N89_11345	COG1830	Aldolase
E5N89_11350	COG2211	Major facilitator Superfamily
E5N89_11355	COG1397	ADP-ribosylglycohydrolase
E5N89_11360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5N89_11365	COG2188	Transcriptional regulator
E5N89_11380	COG5455	response to cobalt ion
E5N89_11385	COG3539	Fimbrial protein
E5N89_11390	COG3188	usher protein
E5N89_11395	COG3121	Chaperone
E5N89_11420	COG4808	Protein conserved in bacteria
E5N89_11430	COG4807	Protein conserved in bacteria
E5N89_11440	COG3275	phosphorelay sensor kinase activity
E5N89_11455	COG1174	glycine betaine transport
E5N89_11460	COG1125	glycine betaine transport
E5N89_11465	COG1174	glycine betaine transport
E5N89_11470	COG1732	Glycine betaine
E5N89_11480	COG0277	FAD linked oxidase domain protein
E5N89_11485	COG1686	Belongs to the peptidase S11 family
E5N89_11495	COG0586	Pfam SNARE associated Golgi protein
E5N89_11500	COG1028	Short-chain dehydrogenase reductase Sdr
E5N89_11505	COG1538	Outer membrane efflux protein
E5N89_11520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E5N89_11525	COG0625	glutathione transferase activity
E5N89_11540	COG2271	Major facilitator Superfamily
E5N89_11555	COG1346	cytolysis
E5N89_11565	COG2949	membrane
E5N89_11605	COG2311	Membrane
E5N89_11625	COG1760	l-serine dehydratase
E5N89_11630	COG0560	Phosphoserine phosphatase
E5N89_11635	COG2271	Major facilitator Superfamily
E5N89_11640	COG4771	TonB-dependent receptor
E5N89_11645	COG0833	amino acid
E5N89_11650	COG0583	DNA-binding transcription factor activity
E5N89_11655	COG2855	membrane
E5N89_11665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5N89_11665	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
E5N89_11665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5N89_11670	COG1105	Belongs to the carbohydrate kinase PfkB family
E5N89_11705	COG0523	cobalamin synthesis protein
E5N89_11710	COG0671	phosphoesterase, PA-phosphatase related
E5N89_11715	COG0791	NLP P60 protein
E5N89_11720	COG2200	EAL domain
E5N89_11725	COG4166	transmembrane transport
E5N89_11730	COG4174	ABC transporter (Permease)
E5N89_11735	COG4239	(ABC) transporter, permease
E5N89_11740	COG4172	Belongs to the ABC transporter superfamily
E5N89_11750	COG2814	Major facilitator Superfamily
E5N89_11755	COG1187	pseudouridine synthase activity
E5N89_11760	COG1061	Type III restriction enzyme res subunit
E5N89_11855	COG1403	HNH endonuclease
E5N89_11875	COG5301	cellulose 1,4-beta-cellobiosidase activity
E5N89_11890	COG2197	response regulator
E5N89_11895	COG3088	subunit of a heme lyase
E5N89_11895	COG4235	cytochrome complex assembly
E5N89_11905	COG1138	Cytochrome C-type biogenesis protein
E5N89_11915	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5N89_11920	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5N89_11925	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5N89_11935	COG3005	denitrification pathway
E5N89_11940	COG3043	anaerobic respiration
E5N89_11945	COG0348	domain, Protein
E5N89_11950	COG0437	4 iron, 4 sulfur cluster binding
E5N89_11960	COG3062	negative regulation of establishment of protein localization
E5N89_11965	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5N89_11965	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5N89_11975	COG4615	Cyclic peptide transporter
E5N89_11995	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E5N89_12000	COG0642	Histidine kinase
E5N89_12000	COG2198	Histidine kinase
E5N89_12020	COG4948	Mandelate Racemase Muconate Lactonizing
E5N89_12050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E5N89_12055	COG2814	Major facilitator Superfamily
E5N89_12060	COG0583	DNA-binding transcription factor activity
E5N89_12065	COG0584	glycerophosphoryl diester phosphodiesterase
E5N89_12070	COG2271	Major facilitator Superfamily
E5N89_12075	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E5N89_12085	COG0247	lactate metabolic process
E5N89_12105	COG2271	Major facilitator Superfamily
E5N89_12115	COG1414	Transcriptional regulator
E5N89_12205	COG1169	isochorismate synthase
E5N89_12210	COG4575	ribosome binding
E5N89_12215	COG2153	protein acetylation
E5N89_12225	COG0784	Response regulator, receiver
E5N89_12225	COG0835	chemotaxis
E5N89_12230	COG2304	oxidoreductase activity
E5N89_12245	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E5N89_12250	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E5N89_12260	COG0839	Belongs to the complex I subunit 6 family
E5N89_12275	COG1034	ATP synthesis coupled electron transport
E5N89_12285	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
E5N89_12310	COG0583	DNA-binding transcription factor activity
E5N89_12315	COG0436	Aminotransferase
E5N89_12330	COG0471	metal ion transport
E5N89_12330	COG0490	domain, Protein
E5N89_12335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E5N89_12350	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
E5N89_12360	COG1288	antiporter activity
E5N89_12365	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
E5N89_12370	COG3959	Transketolase, thiamine diphosphate binding domain
E5N89_12375	COG3037	sugar-specific permease SgaT UlaA
E5N89_12385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N89_12390	COG1609	Transcriptional regulator
E5N89_12395	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
E5N89_12400	COG0622	Phosphoesterase
E5N89_12405	COG0625	glutathione transferase activity
E5N89_12410	COG0625	glutathione transferase activity
E5N89_12415	COG1090	epimerase
E5N89_12425	COG4160	amino acid transport
E5N89_12430	COG4215	(ABC) transporter
E5N89_12445	COG0163	prenyltransferase activity
E5N89_12450	COG0833	amino acid
E5N89_12455	COG3457	Alanine racemase
E5N89_12460	COG0531	amino acid
E5N89_12470	COG3829	transcription factor binding
E5N89_12475	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
E5N89_12480	COG1286	toxin biosynthetic process
E5N89_12485	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
E5N89_12490	COG0285	dihydrofolate synthase activity
E5N89_12500	COG0586	Pfam SNARE associated Golgi protein
E5N89_12510	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E5N89_12535	COG3423	Transcriptional regulator
E5N89_12555	COG1943	Transposase
E5N89_12560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E5N89_12575	COG3101	peptidyl-lysine hydroxylation
E5N89_12580	COG0730	response to heat
E5N89_12595	COG2890	protein-(glutamine-N5) methyltransferase activity
E5N89_12605	COG2062	phosphohistidine phosphatase, SixA
E5N89_12620	COG3691	Protein conserved in bacteria
E5N89_12635	COG2116	formate transmembrane transporter activity
E5N89_12660	COG1840	ABC-type Fe3 transport system, periplasmic component
E5N89_12675	COG1560	Kdo2-lipid A biosynthetic process
E5N89_12685	COG0436	Aminotransferase
E5N89_12700	COG3961	Belongs to the TPP enzyme family
E5N89_12705	COG0667	Aldo Keto reductase
E5N89_12720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E5N89_12725	COG2199	diguanylate cyclase activity
E5N89_12725	COG2200	EAL domain
E5N89_12740	COG3415	Transposase
E5N89_12745	COG3415	Transposase
E5N89_12765	COG0583	DNA-binding transcription factor activity
E5N89_12775	COG2211	Major facilitator Superfamily
E5N89_12780	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
E5N89_12790	COG0583	DNA-binding transcription factor activity
E5N89_12795	COG0385	Bile acid
E5N89_12800	COG3530	Putative quorum-sensing-regulated virulence factor
E5N89_12820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E5N89_12825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N89_12835	COG2190	(PTS) system
E5N89_12880	COG4208	sulfate ABC transporter
E5N89_12895	COG1028	Short-chain dehydrogenase reductase Sdr
E5N89_12900	COG1943	Transposase
E5N89_12905	COG2837	iron assimilation
E5N89_12955	COG4816	utilization protein
E5N89_12985	COG4820	ethanolamine utilization protein (EutJ)
E5N89_13020	COG4917	ethanolamine utilization protein
E5N89_13040	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E5N89_13050	COG5342	invasion associated locus B
E5N89_13055	COG0494	nUDIX hydrolase
E5N89_13065	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5N89_13065	COG0493	'glutamate synthase
E5N89_13070	COG3850	Histidine kinase
E5N89_13075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5N89_13085	COG1393	Belongs to the ArsC family
E5N89_13105	COG2321	neutral zinc metallopeptidase
E5N89_13115	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
E5N89_13125	COG2716	regulation of RNA biosynthetic process
E5N89_13130	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E5N89_13135	COG1929	Belongs to the glycerate kinase type-1 family
E5N89_13140	COG0628	permease
E5N89_13145	COG4783	chaperone-mediated protein folding
E5N89_13150	COG1393	Belongs to the ArsC family
E5N89_13160	COG2233	PERMEase
E5N89_13175	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
E5N89_13185	COG0248	Ppx GppA phosphatase
E5N89_13190	COG2200	EAL domain
E5N89_13230	COG0516	GMP reductase activity
E5N89_13230	COG0517	IMP dehydrogenase activity
E5N89_13270	COG1645	bacterial-type flagellum-dependent swarming motility
E5N89_13285	COG2976	Protein conserved in bacteria
E5N89_13325	COG0437	4 iron, 4 sulfur cluster binding
E5N89_13330	COG0243	molybdopterin cofactor binding
E5N89_13335	COG4953	penicillin-binding protein 1C
E5N89_13340	COG2373	Large extracellular alpha-helical protein
E5N89_13345	COG2897	thiosulfate sulfurtransferase activity
E5N89_13365	COG2975	iron-sulfur cluster assembly
E5N89_13370	COG0633	Ferredoxin
E5N89_13390	COG0822	iron-sulfur transferase activity
E5N89_13430	COG2221	Nitrite and sulphite reductase 4Fe-4S
E5N89_13435	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
E5N89_13445	COG3711	transcriptional antiterminator
E5N89_13450	COG2814	Major facilitator Superfamily
E5N89_13455	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
E5N89_13460	COG1017	nitric oxide dioxygenase activity
E5N89_13460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E5N89_13465	COG3710	Transcriptional regulator
E5N89_13470	COG0531	amino acid
E5N89_13475	COG1982	Orn Lys Arg decarboxylase major
E5N89_13480	COG3104	oligopeptide transport
E5N89_13485	COG0347	Belongs to the P(II) protein family
E5N89_13490	COG2204	response regulator
E5N89_13495	COG3170	Tfp pilus assembly protein FimV
E5N89_13500	COG2205	protein histidine kinase activity
E5N89_13520	COG0590	tRNA wobble adenosine to inosine editing
E5N89_13525	COG0560	Phosphoserine phosphatase
E5N89_13530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5N89_13530	COG1263	PTS System
E5N89_13540	COG1737	Transcriptional regulator
E5N89_13545	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E5N89_13555	COG0583	DNA-binding transcription factor activity
E5N89_13560	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5N89_13590	COG0681	Belongs to the peptidase S26 family
E5N89_13630	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E5N89_13650	COG5301	cellulose 1,4-beta-cellobiosidase activity
E5N89_13760	COG4220	transposase activity
E5N89_13870	COG1484	DNA-dependent DNA replication
E5N89_13905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5N89_13930	COG3086	response to oxidative stress
E5N89_13970	COG0513	Belongs to the DEAD box helicase family
E5N89_13975	COG0583	DNA-binding transcription factor activity
E5N89_13995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E5N89_14000	COG3118	belongs to the thioredoxin family
E5N89_14015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E5N89_14020	COG5544	Lipoprotein
E5N89_14025	COG0477	Major facilitator Superfamily
E5N89_14055	COG0542	response to heat
E5N89_14065	COG0564	pseudouridine synthase activity
E5N89_14070	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5N89_14075	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E5N89_14085	COG0077	Prephenate dehydratase
E5N89_14085	COG1605	Chorismate mutase
E5N89_14095	COG1605	Chorismate mutase
E5N89_14095	COG0287	Prephenate dehydrogenase
E5N89_14100	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E5N89_14110	COG2199	diguanylate cyclase activity
E5N89_14135	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E5N89_14140	COG4137	Cytochrome C assembly protein
E5N89_14145	COG4536	flavin adenine dinucleotide binding
E5N89_14165	COG0497	DNA recombination
E5N89_14180	COG2867	negative regulation of translational initiation
E5N89_14205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5N89_14215	COG0582	viral genome integration into host DNA
E5N89_14220	COG0582	viral genome integration into host DNA
E5N89_14250	COG4133	protoheme IX ABC transporter activity
E5N89_14265	COG3423	Transcriptional regulator
E5N89_14285	COG0673	inositol 2-dehydrogenase activity
E5N89_14295	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
E5N89_14300	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
E5N89_14310	COG2190	(PTS) system
E5N89_14310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5N89_14310	COG1263	PTS System
E5N89_14325	COG3316	Transposase and inactivated derivatives
E5N89_14350	COG3316	Transposase and inactivated derivatives
E5N89_14390	COG3316	Transposase and inactivated derivatives
E5N89_14405	COG3300	MHYT domain
E5N89_14405	COG5001	Diguanylate cyclase
E5N89_14465	COG0640	Transcriptional regulator
E5N89_14480	COG0786	glutamate:sodium symporter activity
E5N89_14540	COG3316	Transposase and inactivated derivatives
E5N89_14565	COG2819	hydrolase of the alpha beta superfamily
E5N89_14585	COG2990	Protein conserved in bacteria
E5N89_14600	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
E5N89_14605	COG0642	Histidine kinase
E5N89_14635	COG0579	oxidoreductase
E5N89_14640	COG1012	belongs to the aldehyde dehydrogenase family
E5N89_14645	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E5N89_14650	COG1113	amino acid transport
E5N89_14655	COG1802	Transcriptional regulator
E5N89_14660	COG1652	LysM domain
E5N89_14670	COG0401	homolog of Blt101
E5N89_14675	COG0640	Transcriptional regulator
E5N89_14680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E5N89_14690	COG2916	Histone family protein nucleoid-structuring protein H-NS
E5N89_14710	COG4575	ribosome binding
E5N89_14720	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E5N89_14765	COG2814	Major facilitator Superfamily
E5N89_14770	COG1846	Transcriptional regulator
E5N89_14775	COG1566	PFAM secretion protein HlyD family protein
E5N89_14780	COG2814	Major facilitator Superfamily
E5N89_14800	COG1238	metal cluster binding
E5N89_14805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E5N89_14860	COG1546	Belongs to the CinA family
E5N89_14870	COG2951	lytic endotransglycosylase activity
E5N89_14875	COG3730	PTS system glucitol sorbitol-specific
E5N89_14880	COG3732	PTS system glucitol sorbitol-specific
E5N89_14890	COG1028	Short-chain dehydrogenase reductase Sdr
E5N89_14895	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N89_14900	COG1349	DNA-binding transcription factor activity
E5N89_14925	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
E5N89_14930	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5N89_14940	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E5N89_14950	COG3260	NADH ubiquinone oxidoreductase 20
E5N89_14955	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E5N89_14960	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
E5N89_14960	COG3261	NADH dehydrogenase
E5N89_14965	COG0650	Formate hydrogenlyase subunit 4
E5N89_14970	COG0651	ATP synthesis coupled electron transport
E5N89_14975	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5N89_14985	COG0375	protein maturation
E5N89_14990	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
E5N89_14995	COG0298	carbon dioxide binding
E5N89_15000	COG0409	Hydrogenase expression formation protein
E5N89_15005	COG0309	Hydrogenase expression formation protein (HypE)
E5N89_15025	COG1121	(ABC) transporter
E5N89_15030	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E5N89_15035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E5N89_15185	COG1157	protein secretion by the type III secretion system
E5N89_15195	COG4789	Type iii secretion
E5N89_15210	COG2207	Transcriptional regulator
E5N89_15275	COG0477	Major facilitator Superfamily
E5N89_15285	COG2610	gluconate transmembrane transporter activity
E5N89_15290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E5N89_15295	COG3622	Belongs to the hyi family
E5N89_15300	COG0235	Class ii aldolase
E5N89_15310	COG2084	Dehydrogenase
E5N89_15315	COG1349	DNA-binding transcription factor activity
E5N89_15325	COG0163	prenyltransferase activity
E5N89_15330	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
E5N89_15400	COG2234	aminopeptidase activity
E5N89_15405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E5N89_15410	COG1518	maintenance of DNA repeat elements
E5N89_15425	COG1857	crispr-associated protein
E5N89_15465	COG0720	synthase
E5N89_15470	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E5N89_15470	COG0321	lipoyl(octanoyl) transferase activity
E5N89_15475	COG0602	queuosine metabolic process
E5N89_15490	COG3956	TIGRFAM MazG family protein
E5N89_15505	COG3609	addiction module antidote protein, CC2985 family
E5N89_15510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E5N89_15520	COG2205	protein histidine kinase activity
E5N89_15520	COG3437	response regulator, receiver
E5N89_15520	COG3850	Histidine kinase
E5N89_15520	COG4999	Histidine kinase
E5N89_15525	COG1929	Belongs to the glycerate kinase type-1 family
E5N89_15530	COG4948	Mandelate Racemase Muconate Lactonizing
E5N89_15535	COG4948	Mandelate Racemase Muconate Lactonizing
E5N89_15540	COG2271	Major facilitator Superfamily
E5N89_15550	COG0716	FMN binding
E5N89_15560	COG3098	single-species biofilm formation
E5N89_15580	COG1611	Belongs to the LOG family
E5N89_15585	COG0814	amino acid
E5N89_15590	COG1760	l-serine dehydratase
E5N89_15600	COG1454	alcohol dehydrogenase
E5N89_15605	COG0235	Class ii aldolase
E5N89_15610	COG0738	Major facilitator superfamily
E5N89_15630	COG1349	DNA-binding transcription factor activity
E5N89_15640	COG2363	Small membrane protein
E5N89_15645	COG0583	DNA-binding transcription factor activity
E5N89_15655	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E5N89_15660	COG2166	iron-sulfur cluster assembly
E5N89_15665	COG2962	Rard protein
E5N89_15670	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E5N89_15675	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
E5N89_15685	COG0860	N-Acetylmuramoyl-L-alanine amidase
E5N89_15695	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E5N89_15700	COG1074	ATP-dependent DNA helicase activity
E5N89_15710	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
E5N89_15715	COG4967	type IV pilus modification protein PilV
E5N89_15725	COG4795	General secretion pathway protein
E5N89_15730	COG2165	general secretion pathway protein
E5N89_15760	COG0861	Integral membrane protein TerC family
E5N89_15770	COG0667	Aldo Keto reductase
E5N89_15790	COG1609	Transcriptional regulator
E5N89_15795	COG0019	diaminopimelate decarboxylase activity
E5N89_15800	COG0583	DNA-binding transcription factor activity
E5N89_15805	COG1794	racemase activity, acting on amino acids and derivatives
E5N89_15810	COG2814	Major facilitator Superfamily
E5N89_15815	COG1028	Short-chain dehydrogenase reductase Sdr
E5N89_15825	COG0183	Belongs to the thiolase family
E5N89_15840	COG0814	amino acid
E5N89_15875	COG3188	usher protein
E5N89_15925	COG4942	peptidase
E5N89_15955	COG4974	Belongs to the 'phage' integrase family
E5N89_15960	COG0716	FMN binding
E5N89_15980	COG1272	protein, Hemolysin III
E5N89_15990	COG2723	6-phospho-beta-galactosidase activity
E5N89_16020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E5N89_16025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E5N89_16030	COG0006	proline dipeptidase activity
E5N89_16050	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E5N89_16055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E5N89_16070	COG2968	Membrane
E5N89_16080	COG0668	transmembrane transport
E5N89_16085	COG0191	fructose-bisphosphate aldolase activity
E5N89_16115	COG1122	ATPase activity
E5N89_16120	COG1122	ATPase activity
E5N89_16125	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E5N89_16130	COG0501	Belongs to the peptidase M48B family
E5N89_16140	COG2267	carboxylic ester hydrolase activity
E5N89_16145	COG2731	YhcH YjgK YiaL family protein
E5N89_16150	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E5N89_16155	COG1063	alcohol dehydrogenase
E5N89_16160	COG0246	Mannitol dehydrogenase
E5N89_16170	COG2186	Transcriptional regulator
E5N89_16180	COG1166	arginine decarboxylase activity
E5N89_16200	COG2814	Major facilitator Superfamily
E5N89_16210	COG2356	endonuclease I
E5N89_16215	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E5N89_16240	COG2805	Type II/IV secretion system protein
E5N89_16245	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E5N89_16250	COG0762	integral membrane protein
E5N89_16265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E5N89_16275	COG0252	asparaginase activity
E5N89_16285	COG3171	Protein conserved in bacteria
E5N89_16310	COG2211	Major facilitator Superfamily
E5N89_16315	COG1982	Orn Lys Arg decarboxylase major
E5N89_16320	COG1811	Na channel or pump
E5N89_16335	COG0427	acetyl-CoA hydrolase
E5N89_16340	COG2030	dehydratase
E5N89_16375	COG0531	amino acid
E5N89_16385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E5N89_16390	COG1012	belongs to the aldehyde dehydrogenase family
E5N89_16415	COG2271	Major facilitator Superfamily
E5N89_16425	COG0246	Mannitol dehydrogenase
E5N89_16440	COG0754	glutathionylspermidine amidase activity
E5N89_16445	COG0625	glutathione transferase activity
E5N89_16460	COG0298	carbon dioxide binding
E5N89_16465	COG0375	protein maturation
E5N89_16470	COG1773	rubredoxin
E5N89_16475	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E5N89_16480	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
E5N89_16485	COG5557	Pfam Polysulphide reductase, NrfD
E5N89_16490	COG0437	4 iron, 4 sulfur cluster binding
E5N89_16495	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E5N89_16505	COG0840	transmembrane signaling receptor activity
E5N89_16530	COG1028	Short-chain dehydrogenase reductase Sdr
E5N89_16535	COG0848	biopolymer transport protein
E5N89_16540	COG0811	peptide transport
E5N89_16550	COG0586	Pfam SNARE associated Golgi protein
E5N89_16555	COG2207	Transcriptional regulator
E5N89_16560	COG1979	alcohol dehydrogenase
E5N89_16570	COG0471	metal ion transport
E5N89_16610	COG2132	Multicopper oxidase
E5N89_16615	COG0204	Acyl-transferase
E5N89_16625	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E5N89_16630	COG3111	PFAM Bacterial OB fold (BOF) protein
E5N89_16635	COG0745	RESPONSE REGULATOR receiver
E5N89_16645	COG2249	NAD(P)H dehydrogenase (quinone) activity
E5N89_16650	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
E5N89_16655	COG0187	DNA topoisomerase II activity
E5N89_16660	COG3150	esterase
E5N89_16665	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
E5N89_16670	COG3151	Protein conserved in bacteria
E5N89_16675	COG0494	nUDIX hydrolase
E5N89_16690	COG0754	glutathionylspermidine amidase activity
E5N89_16695	COG3384	dioxygenase
E5N89_16735	COG1585	Membrane protein implicated in regulation of membrane protease activity
E5N89_16740	COG2268	Band 7 protein
E5N89_16760	COG3025	triphosphatase activity
E5N89_16765	COG4991	sh3 domain protein
E5N89_16780	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
E5N89_16810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E5N89_16855	COG5301	cellulose 1,4-beta-cellobiosidase activity
E5N89_16950	COG4695	Portal protein
E5N89_17015	COG4974	Belongs to the 'phage' integrase family
E5N89_17025	COG2375	cellular response to nickel ion
E5N89_17030	COG1695	Transcriptional regulator
E5N89_17035	COG0840	transmembrane signaling receptor activity
E5N89_17040	COG0840	transmembrane signaling receptor activity
E5N89_17050	COG0446	pyridine nucleotide-disulphide oxidoreductase
E5N89_17050	COG1902	pentaerythritol trinitrate reductase activity
E5N89_17060	COG1451	nucleotide metabolic process
E5N89_17065	COG2949	membrane
E5N89_17070	COG0673	inositol 2-dehydrogenase activity
E5N89_17085	COG0586	Pfam SNARE associated Golgi protein
E5N89_17095	COG1422	Protein of unknown function (DUF1090)
E5N89_17100	COG4575	ribosome binding
E5N89_17105	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
E5N89_17115	COG2259	Doxx family
E5N89_17120	COG0435	Glutathione S-transferase
E5N89_17125	COG3152	Membrane
E5N89_17130	COG0583	DNA-binding transcription factor activity
E5N89_17135	COG1741	Belongs to the pirin family
E5N89_17150	COG0814	amino acid
E5N89_17155	COG1760	l-serine dehydratase
E5N89_17160	COG1882	Formate acetyltransferase
E5N89_17180	COG0583	DNA-binding transcription factor activity
E5N89_17190	COG1929	Belongs to the glycerate kinase type-1 family
E5N89_17195	COG2084	Dehydrogenase
E5N89_17205	COG2721	sulfolactate sulfo-lyase activity
E5N89_17210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5N89_17215	COG1349	DNA-binding transcription factor activity
E5N89_17220	COG0191	fructose-bisphosphate aldolase activity
E5N89_17225	COG1105	Belongs to the carbohydrate kinase PfkB family
E5N89_17230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5N89_17230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5N89_17230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N89_17245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N89_17250	COG3414	Phosphotransferase system galactitol-specific IIB component
E5N89_17255	COG3775	system Galactitol-specific IIC component
E5N89_17260	COG1063	alcohol dehydrogenase
E5N89_17270	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E5N89_17290	COG2823	Periplasmic or secreted lipoprotein
E5N89_17295	COG0702	epimerase
E5N89_17300	COG0693	protein deglycase activity
E5N89_17315	COG3153	acetyltransferase
E5N89_17335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E5N89_17340	COG3034	peptidoglycan biosynthetic process
E5N89_17350	COG0814	amino acid
E5N89_17355	COG0513	Belongs to the DEAD box helicase family
E5N89_17425	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E5N89_17435	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
E5N89_17440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E5N89_17450	COG1534	Rna-binding protein
E5N89_17455	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E5N89_17460	COG2027	D-alanyl-D-alanine carboxypeptidase
E5N89_17470	COG0697	spore germination
E5N89_17485	COG0142	geranyltranstransferase activity
E5N89_17490	COG3423	Transcriptional regulator
E5N89_17500	COG5007	Belongs to the BolA IbaG family
E5N89_17505	COG3113	response to antibiotic
E5N89_17510	COG2854	intermembrane phospholipid transfer
E5N89_17515	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E5N89_17520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E5N89_17525	COG1127	ABC transporter
E5N89_17530	COG0530	calcium, potassium:sodium antiporter activity
E5N89_17545	COG3117	lipopolysaccharide transmembrane transporter activity
E5N89_17550	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
E5N89_17555	COG1137	ATPase activity
E5N89_17570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N89_17580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N89_17585	COG0515	serine threonine protein kinase
E5N89_17595	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
E5N89_17600	COG2198	Histidine kinase
E5N89_17600	COG0784	Response regulator, receiver
E5N89_17600	COG5002	protein histidine kinase activity
E5N89_17605	COG1242	4 iron, 4 sulfur cluster binding
E5N89_17610	COG0067	glutamate synthase
E5N89_17610	COG0070	glutamate synthase
E5N89_17610	COG0069	glutamate synthase activity
E5N89_17615	COG0493	'glutamate synthase
E5N89_17620	COG4804	nuclease activity
E5N89_17625	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
E5N89_17630	COG0402	S-adenosylhomocysteine deaminase activity
E5N89_17635	COG2731	YhcH YjgK YiaL family protein
E5N89_17665	COG2969	positive regulation of protein catabolic process
E5N89_17670	COG0625	glutathione transferase activity
E5N89_17695	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
E5N89_17700	COG3105	Protein conserved in bacteria
E5N89_17705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E5N89_17715	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
E5N89_17745	COG0471	metal ion transport
E5N89_17780	COG2732	(Barnase) inhibitor
E5N89_17800	COG0583	DNA-binding transcription factor activity
E5N89_17805	COG0312	modulator of DNA gyrase
E5N89_17810	COG3164	Protein of unknown function
E5N89_17815	COG1530	ribonuclease E activity
E5N89_17825	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
E5N89_17830	COG1792	Involved in formation and maintenance of cell shape
E5N89_17835	COG1077	Cell shape determining protein MreB Mrl
E5N89_17840	COG2199	diguanylate cyclase activity
E5N89_17840	COG2200	EAL domain
E5N89_17845	COG0604	alcohol dehydrogenase
E5N89_17860	COG0511	ligase activity, forming carbon-carbon bonds
E5N89_17865	COG0439	Biotin carboxylase
E5N89_17870	COG3924	membrane
E5N89_17875	COG4145	pantothenate transmembrane transporter activity
E5N89_17885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E5N89_17895	COG2189	Belongs to the N(4) N(6)-methyltransferase family
E5N89_17910	COG1309	transcriptional regulator
E5N89_17915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5N89_17920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E5N89_17960	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E5N89_17980	COG0551	DNA topoisomerase type I activity
E5N89_17990	COG0758	DNA mediated transformation
E5N89_18010	COG0569	domain protein
E5N89_18020	COG3036	rescue of stalled ribosome
E5N89_18025	COG0789	Transcriptional regulator
E5N89_18065	COG0201	protein transport
E5N89_18115	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
E5N89_18170	COG0051	transcription antitermination factor activity, RNA binding
E5N89_18185	COG2906	2 iron, 2 sulfur cluster binding
E5N89_18225	COG2964	Protein conserved in bacteria
E5N89_18235	COG0545	Peptidyl-prolyl cis-trans isomerase
E5N89_18245	COG1047	Peptidyl-prolyl cis-trans
E5N89_18250	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
E5N89_18265	COG0488	(ABC) transporter
E5N89_18280	COG0429	hydrolase of the alpha beta-hydrolase fold
E5N89_18290	COG3954	Phosphoribulokinase
E5N89_18295	COG1765	OsmC-like protein
E5N89_18305	COG1289	transmembrane transporter activity
E5N89_18340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E5N89_18345	COG2146	nitrite reductase [NAD(P)H] activity
E5N89_18365	COG1943	Transposase
E5N89_18375	COG0180	Tryptophanyl-tRNA synthetase
E5N89_18385	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E5N89_18390	COG0338	D12 class N6 adenine-specific DNA methyltransferase
E5N89_18395	COG3266	domain, Protein
E5N89_18410	COG4796	Type ii and iii secretion system protein
E5N89_18425	COG3166	PFAM Fimbrial assembly family protein
E5N89_18430	COG4972	Pilus assembly protein
E5N89_18435	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
E5N89_18440	COG0494	nUDIX hydrolase
E5N89_18450	COG1011	Hydrolase
E5N89_18455	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E5N89_18465	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E5N89_18480	COG0745	RESPONSE REGULATOR receiver
E5N89_18490	COG2183	response to ionizing radiation
E5N89_18495	COG1918	ferrous iron import across plasma membrane
E5N89_18510	COG5464	transposase or invertase
E5N89_18530	COG2610	gluconate transmembrane transporter activity
E5N89_18535	COG1640	4-alpha-glucanotransferase
E5N89_18540	COG0058	SHG alpha-glucan phosphorylase activity
E5N89_18550	COG3041	Addiction module toxin RelE StbE family
E5N89_18555	COG3077	Addiction module antitoxin, RelB DinJ family
E5N89_18565	COG1690	Belongs to the RtcB family
E5N89_18580	COG4650	regulator
E5N89_18585	COG1349	DNA-binding transcription factor activity
E5N89_18600	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E5N89_18615	COG0371	Dehydrogenase
E5N89_18625	COG0129	dihydroxy-acid dehydratase activity
E5N89_18630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E5N89_18635	COG1414	Transcriptional regulator
E5N89_18640	COG0058	SHG alpha-glucan phosphorylase activity
E5N89_18665	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E5N89_18670	COG2095	MarC family integral membrane protein
E5N89_18675	COG2610	gluconate transmembrane transporter activity
E5N89_18680	COG3265	gluconokinase activity
E5N89_18685	COG1609	Transcriptional regulator
E5N89_18690	COG1741	Belongs to the pirin family
E5N89_18695	COG0673	inositol 2-dehydrogenase activity
E5N89_18700	COG1247	-acetyltransferase
E5N89_18705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5N89_18720	COG1735	metal-dependent hydrolase with the TIM-barrel fold
E5N89_18725	COG0405	Gamma-glutamyltransferase
E5N89_18735	COG0584	glycerophosphoryl diester phosphodiesterase
E5N89_18755	COG1653	transport
E5N89_18770	COG0410	ABC transporter
E5N89_18775	COG0411	ABC transporter
E5N89_18785	COG0559	Belongs to the binding-protein-dependent transport system permease family
E5N89_18790	COG0683	leucine binding
E5N89_18815	COG2177	Part of the ABC transporter FtsEX involved in
E5N89_18820	COG2884	Cell division ATP-binding protein ftsE
E5N89_18825	COG0552	protein localization to endoplasmic reticulum
E5N89_18830	COG0742	ribosomal rna small subunit methyltransferase
E5N89_18835	COG3776	membrane
E5N89_18845	COG3714	YhhN family
E5N89_18865	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E5N89_18880	COG0628	permease
E5N89_18895	COG0842	Transport permease protein
E5N89_18900	COG0842	Transport permease protein
E5N89_18900	COG1129	ABC transporter
E5N89_18905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5N89_18910	COG2081	HI0933 family
E5N89_18915	COG0306	phosphate transporter
E5N89_18945	COG0671	phosphoesterase, PA-phosphatase related
E5N89_18950	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
E5N89_18955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E5N89_18965	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E5N89_18970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5N89_18975	COG2222	sugar isomerase
E5N89_18980	COG2188	Transcriptional regulator
E5N89_19000	COG2197	response regulator
E5N89_19005	COG0583	DNA-binding transcription factor activity
E5N89_19010	COG1295	ribonuclease BN
E5N89_19015	COG0477	Major facilitator Superfamily
E5N89_19020	COG2982	Protein involved in outer membrane biogenesis
E5N89_19025	COG2200	EAL domain
E5N89_19030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5N89_19045	COG2200	EAL domain
E5N89_19045	COG2199	diguanylate cyclase activity
E5N89_19105	COG0814	amino acid
E5N89_19110	COG4608	Belongs to the ABC transporter superfamily
E5N89_19115	COG0444	Belongs to the ABC transporter superfamily
E5N89_19120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E5N89_19125	COG0601	transmembrane transport
E5N89_19130	COG0747	negative chemotaxis
E5N89_19190	COG5571	outer membrane autotransporter
E5N89_19195	COG2818	Glycosylase
E5N89_19200	COG0456	acetyltransferase
E5N89_19205	COG0243	molybdopterin cofactor binding
E5N89_19210	COG2885	chlorophyll binding
E5N89_19225	COG2944	sequence-specific DNA binding
E5N89_19230	COG1278	Cold shock
E5N89_19255	COG2801	Transposase and inactivated derivatives
E5N89_19280	COG3274	enterobacterial common antigen metabolic process
E5N89_19285	COG4682	membrane
E5N89_19290	COG1070	Carbohydrate kinase
E5N89_19300	COG1609	Transcriptional regulator
E5N89_19300	COG2207	Transcriptional regulator
E5N89_19305	COG2992	FlgJ-related protein
E5N89_19310	COG0366	Alpha amylase catalytic
E5N89_19315	COG3977	Valine--pyruvate aminotransferase
E5N89_19320	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E5N89_19325	COG1414	Transcriptional regulator
E5N89_19335	COG2731	YhcH YjgK YiaL family protein
E5N89_19345	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E5N89_19350	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E5N89_19355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E5N89_19360	COG1070	Carbohydrate kinase
E5N89_19365	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
E5N89_19370	COG3623	hexulose-6-phosphate isomerase
E5N89_19375	COG0235	Class ii aldolase
E5N89_19390	COG1012	belongs to the aldehyde dehydrogenase family
E5N89_19395	COG1940	carbohydrate kinase activity
E5N89_19400	COG3276	selenocysteine insertion sequence binding
E5N89_19410	COG0625	glutathione transferase activity
E5N89_19415	COG2213	PTS system mannitol-specific
E5N89_19415	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N89_19425	COG3722	fumarate hydratase activity
E5N89_19455	COG2186	Transcriptional regulator
E5N89_19465	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
E5N89_19470	COG1609	Transcriptional regulator
E5N89_19480	COG2271	Major facilitator Superfamily
E5N89_19500	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E5N89_19505	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E5N89_19515	COG4942	peptidase
E5N89_19520	COG2861	carbohydrate metabolic process
E5N89_19525	COG1216	Glycosyl transferase, family 2
E5N89_19605	COG0438	transferase activity, transferring glycosyl groups
E5N89_19610	COG0859	PFAM glycosyl transferase family 9
E5N89_19615	COG1519	Transferase
E5N89_19645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E5N89_19670	COG1561	YicC-like family, N-terminal region
E5N89_19675	COG0583	DNA-binding transcription factor activity
E5N89_19685	COG2860	membrane
E5N89_19705	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E5N89_19710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E5N89_19715	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
E5N89_19725	COG0786	glutamate:sodium symporter activity
E5N89_19730	COG2233	PERMEase
E5N89_19735	COG2982	Protein involved in outer membrane biogenesis
E5N89_19740	COG1501	Belongs to the glycosyl hydrolase 31 family
E5N89_19745	COG2211	Major facilitator Superfamily
E5N89_19765	COG0419	ATPase involved in DNA repair
E5N89_19790	COG2771	luxR family
E5N89_19805	COG3710	Transcriptional regulator
E5N89_19815	COG1335	isochorismatase
E5N89_19845	COG5464	transposase or invertase
E5N89_19860	COG3716	PTS system mannose fructose sorbose family IID component
E5N89_19865	COG3715	PTS system
E5N89_19870	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N89_19870	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5N89_19890	COG2723	6-phospho-beta-galactosidase activity
E5N89_19925	COG3775	system Galactitol-specific IIC component
E5N89_19930	COG3414	Phosphotransferase system galactitol-specific IIB component
E5N89_19935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N89_19935	COG3711	transcriptional antiterminator
E5N89_19975	COG0738	Major facilitator superfamily
E5N89_19980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5N89_19985	COG1349	DNA-binding transcription factor activity
E5N89_19990	COG0440	acetolactate synthase activity
E5N89_19995	COG0028	Belongs to the TPP enzyme family
E5N89_20020	COG2814	Major facilitator Superfamily
E5N89_20030	COG0583	DNA-binding transcription factor activity
E5N89_20035	COG2610	gluconate transmembrane transporter activity
E5N89_20045	COG0641	radical SAM
E5N89_20055	COG2149	membrane
E5N89_20075	COG5645	(Lipo)protein
E5N89_20080	COG0823	Involved in the tonB-independent uptake of proteins
E5N89_20085	COG4235	cytochrome complex assembly
E5N89_20085	COG3088	subunit of a heme lyase
E5N89_20095	COG1138	Cytochrome C-type biogenesis protein
E5N89_20105	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5N89_20110	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5N89_20115	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E5N89_20125	COG1858	cytochrome C peroxidase
E5N89_20140	COG3005	denitrification pathway
E5N89_20145	COG0745	RESPONSE REGULATOR receiver
E5N89_20150	COG1879	ABC-type sugar transport system periplasmic component
E5N89_20155	COG2198	Histidine kinase
E5N89_20155	COG0784	Response regulator, receiver
E5N89_20155	COG2205	protein histidine kinase activity
E5N89_20160	COG2271	Major facilitator Superfamily
E5N89_20170	COG0800	Aldolase
E5N89_20175	COG3734	2-keto-3-deoxy-galactonokinase
E5N89_20180	COG2186	Transcriptional regulator
E5N89_20185	COG0561	phosphatase activity
E5N89_20190	COG2271	Major facilitator Superfamily
E5N89_20195	COG4948	Mandelate Racemase Muconate Lactonizing
E5N89_20205	COG0187	DNA topoisomerase II activity
E5N89_20275	COG2091	lysine biosynthetic process via aminoadipic acid
E5N89_20280	COG0431	NADPH-dependent FMN reductase
E5N89_20285	COG2252	PERMEase
E5N89_20290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E5N89_20295	COG0704	Plays a role in the regulation of phosphate uptake
E5N89_20305	COG0581	inorganic phosphate transmembrane transporter activity
E5N89_20310	COG0573	inorganic phosphate transmembrane transporter activity
E5N89_20315	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E5N89_20320	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5N89_20320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5N89_20320	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
E5N89_20325	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
E5N89_20330	COG4533	DNA binding
E5N89_20390	COG3312	ion transport
E5N89_20405	COG0716	FMN binding
E5N89_20410	COG1522	sequence-specific DNA binding
E5N89_20445	COG1172	Belongs to the binding-protein-dependent transport system permease family
E5N89_20450	COG1879	ABC-type sugar transport system periplasmic component
E5N89_20455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5N89_20460	COG1609	Transcriptional regulator
E5N89_20465	COG0477	Major facilitator Superfamily
E5N89_20470	COG2186	Transcriptional regulator
E5N89_20530	COG3978	acetolactate synthase activity
E5N89_20535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E5N89_20560	COG0583	DNA-binding transcription factor activity
E5N89_20570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E5N89_20580	COG3201	nicotinamide mononucleotide transporter
E5N89_20600	COG3118	belongs to the thioredoxin family
E5N89_20610	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
E5N89_20635	COG1088	dTDP-glucose 4,6-dehydratase activity
E5N89_20640	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E5N89_20640	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E5N89_20645	COG0456	acetyltransferase
E5N89_20650	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E5N89_20655	COG2244	polysaccharide biosynthetic process
E5N89_20675	COG1113	amino acid transport
E5N89_20700	COG3071	HemY protein
E5N89_20705	COG2959	enzyme of heme biosynthesis
E5N89_20720	COG3072	Adenylate cyclase
E5N89_20755	COG5567	small periplasmic lipoprotein
E5N89_20775	COG1011	Hydrolase
E5N89_20805	COG2050	protein possibly involved in aromatic compounds catabolism
E5N89_20810	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
E5N89_20830	COG2267	carboxylic ester hydrolase activity
E5N89_20835	COG0561	phosphatase activity
E5N89_20840	COG0697	spore germination
E5N89_20845	COG0583	DNA-binding transcription factor activity
E5N89_20860	COG0641	radical SAM
E5N89_20870	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
E5N89_20875	COG1322	Protein conserved in bacteria
E5N89_20895	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E5N89_20905	COG0805	protein transport
E5N89_20950	COG1739	Uncharacterized protein family UPF0029
E5N89_20990	COG1763	Mo-molybdopterin cofactor biosynthetic process
E5N89_21000	COG3084	Protein conserved in bacteria
E5N89_21015	COG0204	Acyl-transferase
E5N89_21040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E5N89_21055	COG3852	Histidine kinase
E5N89_21060	COG0174	glutamine synthetase
E5N89_21070	COG0561	phosphatase activity
E5N89_21115	COG1501	Belongs to the glycosyl hydrolase 31 family
E5N89_21120	COG2017	converts alpha-aldose to the beta-anomer
E5N89_21140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5N89_21145	COG1349	DNA-binding transcription factor activity
E5N89_21150	COG1011	Hydrolase
E5N89_21165	COG0456	acetyltransferase
E5N89_21170	COG5499	transcription regulator containing HTH domain
E5N89_21175	COG4680	protein conserved in bacteria
E5N89_21185	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
E5N89_21200	COG2864	formate dehydrogenase
E5N89_21205	COG0437	4 iron, 4 sulfur cluster binding
E5N89_21235	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
E5N89_21250	COG1454	alcohol dehydrogenase
E5N89_21285	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
E5N89_21295	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E5N89_21310	COG2258	MOSC domain
E5N89_21320	COG2205	protein histidine kinase activity
E5N89_21325	COG0745	RESPONSE REGULATOR receiver
E5N89_21330	COG3678	ATP-independent chaperone mediated protein folding
E5N89_21355	COG2211	Major facilitator Superfamily
E5N89_21370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E5N89_21380	COG2134	cdp-diacylglycerol pyrophosphatase
E5N89_21390	COG1070	Carbohydrate kinase
E5N89_21445	COG3152	Membrane
E5N89_21455	COG1494	fructose-1,6-bisphosphatase
E5N89_21465	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E5N89_21480	COG1575	Belongs to the MenA family. Type 1 subfamily
E5N89_21495	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E5N89_21500	COG1609	Transcriptional regulator
E5N89_21505	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E5N89_21530	COG0626	cystathionine gamma-synthase activity
E5N89_21535	COG0527	aspartate kinase activity
E5N89_21535	COG0460	homoserine dehydrogenase
E5N89_21540	COG0668	transmembrane transport
E5N89_21555	COG0737	Belongs to the 5'-nucleotidase family
E5N89_21570	COG3738	Protein conserved in bacteria
E5N89_21575	COG0371	Dehydrogenase
E5N89_21585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N89_21585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N89_21585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E5N89_21590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5N89_21595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5N89_21605	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E5N89_21610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E5N89_21615	COG2207	Transcriptional regulator
E5N89_21650	COG0583	DNA-binding transcription factor activity
E5N89_21750	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E5N89_21755	COG0250	Participates in transcription elongation, termination and antitermination
E5N89_21825	COG2104	thiamine diphosphate biosynthetic process
E5N89_21830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E5N89_21865	COG3068	Protein conserved in bacteria
E5N89_21870	COG0776	regulation of translation
E5N89_21940	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
E5N89_21985	COG3122	Protein conserved in bacteria
E5N89_22025	COG5301	cellulose 1,4-beta-cellobiosidase activity
E5N89_22055	COG2246	polysaccharide biosynthetic process
E5N89_22135	COG0527	aspartate kinase activity
E5N89_22160	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5N89_22220	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
E5N89_22230	COG0534	Mate efflux family protein
E5N89_22240	COG3237	CsbD-like
E5N89_22245	COG0735	belongs to the Fur family
E5N89_22285	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
E5N89_22290	COG5532	Uncharacterized conserved protein (DUF2303)
E5N89_22320	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E5N89_22325	COG4197	protein conserved in bacteria, prophage-related
E5N89_22340	COG1846	Transcriptional regulator
E5N89_22350	COG4725	Belongs to the MT-A70-like family
E5N89_22355	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E5N89_22360	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
E5N89_22370	COG1403	HNH endonuclease
E5N89_22375	COG0484	heat shock protein binding
E5N89_22400	COG3179	chitinase
E5N89_22430	COG4626	Terminase
E5N89_22430	COG1802	Transcriptional regulator
E5N89_22440	COG4695	Portal protein
E5N89_22485	COG4386	tail sheath protein
E5N89_22515	COG4228	DNA circulation
E5N89_22535	COG3299	homolog of phage Mu protein gp47
E5N89_22540	COG3778	Protein conserved in bacteria
E5N89_22570	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E5N89_22590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E5N89_22605	COG0305	Participates in initiation and elongation during chromosome replication
E5N89_22610	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
E5N89_22620	COG3700	Belongs to the class B bacterial acid phosphatase family
E5N89_22625	COG0432	Pfam Uncharacterised protein family UPF0047
E5N89_22630	COG2315	Protein conserved in bacteria
E5N89_22645	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
E5N89_22650	COG0629	single-stranded DNA binding
E5N89_22695	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E5N89_22705	COG0789	Transcriptional regulator
E5N89_22715	COG2252	PERMEase
E5N89_22720	COG0025	NhaP-type Na H and K H
E5N89_22725	COG0583	DNA-binding transcription factor activity
E5N89_22730	COG1380	Effector of murein hydrolase LrgA
E5N89_22735	COG1346	cytolysis
E5N89_22745	COG3162	membrane
E5N89_22760	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
E5N89_22765	COG0437	4 iron, 4 sulfur cluster binding
E5N89_22770	COG3301	Polysulphide reductase, NrfD
E5N89_22775	COG1138	Cytochrome C-type biogenesis protein
E5N89_22780	COG4235	cytochrome complex assembly
E5N89_22785	COG1301	dicarboxylic acid transport
E5N89_22790	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
E5N89_22810	COG2764	glyoxalase bleomycin resistance protein dioxygenase
E5N89_22815	COG2824	Alkylphosphonate utilization operon protein PhnA
E5N89_22845	COG0531	amino acid
E5N89_22850	COG2207	Transcriptional regulator
E5N89_22855	COG1982	Orn Lys Arg decarboxylase major
E5N89_22860	COG2169	Transcriptional regulator
E5N89_22875	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E5N89_22875	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E5N89_22880	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E5N89_22890	COG4565	transcriptional regulatory protein
E5N89_22895	COG3290	protein histidine kinase activity
E5N89_22900	COG0243	molybdopterin cofactor binding
E5N89_22905	COG0437	4 iron, 4 sulfur cluster binding
E5N89_22910	COG3302	dmso reductase anchor subunit
E5N89_22915	COG3381	protein complex oligomerization
E5N89_22940	COG2197	response regulator
E5N89_22975	COG0789	Transcriptional regulator
E5N89_23000	COG0305	Participates in initiation and elongation during chromosome replication
E5N89_23045	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E5N89_23135	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E5N89_23325	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E5N89_23355	COG0739	heme binding
E5N89_23365	COG2132	Multicopper oxidase
E5N89_23370	COG3667	copper resistance
E5N89_23375	COG2372	response to copper ion
E5N89_23380	COG1276	copper resistance
E5N89_23385	COG0745	RESPONSE REGULATOR receiver
E5N89_23390	COG2205	protein histidine kinase activity
E5N89_23400	COG0210	DNA helicase
E5N89_23410	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
E5N89_23420	COG1309	transcriptional regulator
E5N89_23435	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E5N89_23440	COG1027	Aspartate ammonia-lyase
E5N89_23445	COG3030	protein affecting phage T7 exclusion by the F plasmid
E5N89_23450	COG0531	amino acid
E5N89_23490	COG5510	response to toxic substance
E5N89_23500	COG2076	Multidrug Resistance protein
E5N89_23520	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E5N89_23525	COG1053	succinate dehydrogenase
E5N89_23535	COG0531	amino acid
E5N89_23545	COG3264	Mechanosensitive ion channel
E5N89_23545	COG1511	domain protein
E5N89_23565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E5N89_23590	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
E5N89_23590	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E5N89_23595	COG0802	atpase or kinase
E5N89_23620	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E5N89_23625	COG0330	HflC and HflK could
E5N89_23630	COG0330	HflC and HflK could
E5N89_23635	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
E5N89_23650	COG0557	exoribonuclease II activity
E5N89_23660	COG3789	protein conserved in bacteria
E5N89_23680	COG3766	membrane
E5N89_23685	COG5463	Belongs to the UPF0441 family
E5N89_23690	COG0754	glutathionylspermidine amidase activity
E5N89_23695	COG1960	acyl-CoA dehydrogenase activity
E5N89_23705	COG3650	response to hydrogen peroxide
E5N89_23710	COG1073	alpha beta
E5N89_23795	COG3061	Opacity-associated protein A
E5N89_23800	COG0545	Peptidyl-prolyl cis-trans isomerase
E5N89_23805	COG1113	amino acid transport
E5N89_23815	COG0697	spore germination
E5N89_23825	COG1943	Transposase
E5N89_23835	COG1733	regulation of RNA biosynthetic process
E5N89_23850	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
E5N89_23860	COG1253	flavin adenine dinucleotide binding
E5N89_23880	COG2105	PFAM AIG2 family protein
E5N89_23885	COG2271	Major facilitator Superfamily
E5N89_23890	COG3964	amidohydrolase
E5N89_23895	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
E5N89_23905	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E5N89_23910	COG0837	glucose binding
E5N89_23910	COG1737	Transcriptional regulator
E5N89_23915	COG0477	Major facilitator Superfamily
E5N89_23915	COG2814	Major facilitator Superfamily
E5N89_23925	COG0477	Major facilitator Superfamily
E5N89_23925	COG2814	Major facilitator Superfamily
E5N89_23930	COG3718	enzyme involved in inositol metabolism
E5N89_23960	COG5520	Belongs to the glycosyl hydrolase 30 family
E5N89_23965	COG1082	Xylose isomerase domain protein TIM barrel
E5N89_23975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E5N89_23980	COG3962	Belongs to the TPP enzyme family
E5N89_23985	COG0673	inositol 2-dehydrogenase activity
E5N89_23990	COG2814	Major facilitator Superfamily
E5N89_24000	COG1082	Xylose isomerase domain protein TIM barrel
E5N89_24010	COG0312	modulator of DNA gyrase
E5N89_24015	COG3783	Cytochrome b(562)
E5N89_24045	COG3964	amidohydrolase
E5N89_24060	COG3711	transcriptional antiterminator
E5N89_24060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E5N89_24065	COG3077	Addiction module antitoxin, RelB DinJ family
E5N89_24070	COG2026	Addiction module toxin, RelE StbE family
E5N89_24085	COG0366	Alpha amylase catalytic
E5N89_24140	COG1438	arginine binding
E5N89_24145	COG1288	antiporter activity
E5N89_24165	COG2731	YhcH YjgK YiaL family protein
E5N89_24175	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
E5N89_24205	COG2927	DNA polymerase III (CHI subunit)
E5N89_24215	COG0795	lipopolysaccharide-transporting ATPase activity
E5N89_24220	COG0795	lipopolysaccharide-transporting ATPase activity
E5N89_24225	COG1609	Transcriptional regulator
E5N89_24230	COG2610	gluconate transmembrane transporter activity
E5N89_24235	COG1028	Short-chain dehydrogenase reductase Sdr
E5N89_24240	COG1063	alcohol dehydrogenase
E5N89_24245	COG3265	gluconokinase activity
E5N89_24250	COG1064	alcohol dehydrogenase
E5N89_24260	COG0582	viral genome integration into host DNA
E5N89_24265	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E5N89_24265	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
E5N89_24290	COG4133	protoheme IX ABC transporter activity
E5N89_24325	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
E5N89_24330	COG3811	Belongs to the UPF0386 family
E5N89_24355	COG0412	Dienelactone hydrolase
E5N89_24360	COG2186	Transcriptional regulator
E5N89_24380	COG0583	DNA-binding transcription factor activity
E5N89_24385	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E5N89_24390	COG0700	Nucleoside recognition
E5N89_24395	COG3366	ferrous iron transmembrane transporter activity
E5N89_24400	COG0477	Major facilitator Superfamily
E5N89_24405	COG2733	membrane
E5N89_24410	COG2814	Major facilitator Superfamily
E5N89_24415	COG5464	transposase or invertase
E5N89_24420	COG1012	belongs to the aldehyde dehydrogenase family
E5N89_24455	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
E5N89_24460	COG1715	Restriction endonuclease
E5N89_24475	COG0523	cobalamin synthesis protein
E5N89_24480	COG2879	small protein
E5N89_24485	COG1966	Carbon starvation protein
E5N89_24490	COG0840	transmembrane signaling receptor activity
E5N89_24505	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E5N89_24510	COG3715	PTS system
E5N89_24515	COG3716	PTS system mannose fructose sorbose family IID component
E5N89_24520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
E5N89_24540	COG1484	DNA-dependent DNA replication
E5N89_24555	COG2966	Psort location CytoplasmicMembrane, score
E5N89_24560	COG2197	response regulator
E5N89_24565	COG2197	response regulator
E5N89_24570	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E5N89_24575	COG4114	ferric iron reductase
E5N89_24580	COG3706	GGDEF domain
E5N89_24610	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
E5N89_24620	COG1011	Hydrolase
E5N89_24630	COG2823	Periplasmic or secreted lipoprotein
E5N89_24640	COG4667	esterase of the alpha-beta hydrolase superfamily
E5N89_24645	COG0084	hydrolase, TatD family'
E5N89_24650	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E5N89_24655	COG1328	CTP reductase activity
E5N89_24685	COG3188	usher protein
E5N89_24690	COG3121	Chaperone
E5N89_24695	COG3539	Fimbrial protein
E5N89_24710	COG3726	membrane protein affecting hemolysin expression
E5N89_24715	COG0560	Phosphoserine phosphatase
E5N89_24730	COG0488	(ABC) transporter
E5N89_24755	COG3708	Transcriptional regulator
E5N89_24755	COG2207	Transcriptional regulator
E5N89_24760	COG3045	CreA protein
E5N89_24765	COG0745	RESPONSE REGULATOR receiver
E5N89_24770	COG2205	protein histidine kinase activity
E5N89_24775	COG4452	Inner membrane protein CreD
E5N89_24795	COG3121	Chaperone
E5N89_24815	COG0745	RESPONSE REGULATOR receiver
E5N89_24825	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA