locus-tag class description E3384_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) E3384_00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) E3384_00030 ENOG4105CXK mandelate racemase muconate lactonizing E3384_00035 ENOG4105DJB Major Facilitator Superfamily E3384_00040 ENOG410667J hydrolase E3384_00045 ENOG4105EMF GntR family transcriptional regulator E3384_00050 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 E3384_00055 ENOG4108RTU Aldolase E3384_00065 ENOG4105DJB Major Facilitator Superfamily E3384_00070 ENOG4105BZU Histidine kinase E3384_00075 ENOG4108SV3 Tmao reductase system periplasmic protein tort E3384_00080 ENOG4106WF9 DNA-binding transcriptional regulator TorR E3384_00085 ENOG4105CUW cytochrome C-TYPE protein E3384_00090 ENOG4108EM1 reductase E3384_00100 ENOG4105CA0 peroxidase E3384_00110 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) E3384_00115 ENOG41060IM Heme exporter protein E3384_00120 ENOG4105X3C heme exporter protein E3384_00130 ENOG4105DA4 cytochrome c-type biogenesis protein E3384_00135 ENOG4107QX9 Thiol disulfide interChange protein E3384_00140 ENOG4105KWW Biogenesis protein E3384_00145 ENOG4105D99 atp gtp-binding protein E3384_00150 ENOG4105R2A (LipO)protein E3384_00175 ENOG4105VG5 Membrane E3384_00180 ENOG4105JP4 Inner membrane protein yidG E3384_00185 ENOG4105J13 transcriptional regulator E3384_00200 ENOG4105W8I Transcriptional regulator E3384_00210 ENOG4105E5M Multidrug resistance protein D E3384_00235 ENOG4105C7K acetolactate synthase E3384_00240 ENOG4105M71 acetolactate synthase 1 regulatory subunit E3384_00245 ENOG4107FB0 transcriptional regulator DeoR family E3384_00250 ENOG4108RVA ribokinase E3384_00255 ENOG4105EDR glucose galactose transporter E3384_00265 ENOG4108KX4 response regulator E3384_00270 ENOG4105BZU Histidine kinase E3384_00275 ENOG4105CXY transporter E3384_00280 ENOG4105CXY transporter E3384_00285 ENOG4108SAJ Protein of unknown function (DUF1198) E3384_00290 ENOG4105FDP GntR family transcriptional regulator E3384_00300 ENOG41090UW PTS System E3384_00305 ENOG4105DT3 PTS system, galactitol-specific IIc component E3384_00315 ENOG4105D2N Aldolase E3384_00340 ENOG4105CS2 ec 3.2.1.21 E3384_00345 ENOG4105T8A Uncharacterized protein YicS E3384_00360 ENOG4108EQA pts system E3384_00365 ENOG4105ETZ PTS System E3384_00370 ENOG4105F3R pts system mannose fructose sorbose family iid E3384_00385 ENOG4105DNE Transposase E3384_00390 ENOG4108UZ3 Transporter E3384_00400 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic E3384_00415 ENOG4105CHJ isochorismatase hydrolase E3384_00425 ENOG4108TC1 Transcriptional regulator E3384_00430 ENOG4105FV3 E3384_00440 ENOG4105ISV protein with bipartite regulator domain E3384_00460 ENOG4105CT4 transporter E3384_00465 ENOG4105CJQ hydrolase, family 31 E3384_00470 ENOG4105JV1 AsmA family E3384_00475 ENOG4105C2W permease E3384_00480 ENOG4105D6U Sodium Glutamate Symporter E3384_00485 ENOG4105CB5 ATP-dependent DNA helicase recG E3384_00490 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase E3384_00495 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) E3384_00500 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) E3384_00510 ENOG410649J Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity) E3384_00515 ENOG4105EN6 Membrane E3384_00530 ENOG4105DSJ YicC domain protein E3384_00555 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase E3384_00570 ENOG4105W0E 50S ribosomal protein L33 E3384_00585 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase E3384_00590 ENOG4105DKP glycosyl transferase, family 9 E3384_00595 ENOG4107RJ7 Glycosyl transferase (Group 1 E3384_00600 ENOG4107543 (lipo)polysaccharide E3384_00615 ENOG4107XU6 Glycosyl transferase (Group 1 E3384_00620 ENOG4106AH0 Glycosyl Transferase E3384_00625 ENOG4105X1N Glycosyl transferase family 8 E3384_00630 ENOG4108PDR lipopolysaccharide core biosynthesis protein E3384_00635 ENOG4108QD8 lipopolysaccharide core biosynthesis protein E3384_00640 ENOG4107XB0 Lipopolysaccharide 1,2-N-acetylglucosaminetransferase E3384_00645 ENOG4108FRV O-antigen ligase E3384_00650 ENOG4105D16 lipopolysaccharide heptosyltransferase i E3384_00655 ENOG4105XA0 heptosyltransferase ii E3384_00665 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) E3384_00680 ENOG4105K64 Glycosyl transferase, family 2 E3384_00685 ENOG4105PXI polysaccharide deacetylase E3384_00690 ENOG41063SB peptidase E3384_00700 ENOG4107YZP Rhodanese domain protein E3384_00705 ENOG4105VW4 glutaredoxin 3 E3384_00720 ENOG4105D7W serine acetyltransferase E3384_00725 ENOG4105DJB Major Facilitator Superfamily E3384_00730 ENOG4105DIA mandelate racemase muconate lactonizing E3384_00735 ENOG4105ETE Transcriptional regulator (LacI family E3384_00740 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) E3384_00750 ENOG41073TP transcriptional regulator E3384_00755 ENOG4105DAA L-lactate E3384_00760 ENOG4105EUR Domain-Containing protein E3384_00765 ENOG4108WY4 inner membrane lipoprotein E3384_00770 ENOG4108YYI Protein of unknown function (DUF2810) E3384_00780 ENOG4105E61 Mannitol repressor protein E3384_00790 ENOG4105CTS PTS system mannitol-specific E3384_00800 ENOG4105FP6 Protein of unknown function (DUF3302) E3384_00805 ENOG4105EFX secretion protein, HlyD family E3384_00810 ENOG4108U78 Glutathione S-transferase E3384_00820 ENOG4105EM7 Selenocysteine-specific translation elongation factor E3384_00825 ENOG41066F8 ROK family E3384_00830 ENOG4105C26 Dehydrogenase E3384_00845 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase E3384_00850 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase E3384_00855 ENOG4105H6Q decarboxylase E3384_00860 ENOG4105CMG Carbohydrate kinase E3384_00865 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit E3384_00870 ENOG4105CG6 trap dicarboxylate transporter dctm subunit E3384_00875 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter E3384_00880 ENOG4108M5W E3384_00885 ENOG4108R66 Conserved Protein E3384_00890 ENOG4105DG4 malate L-lactate dehydrogenase E3384_00895 ENOG4105J4Q Transcriptional regulator E3384_00900 ENOG4108XIB electron transport protein ysaA E3384_00905 ENOG4105JKW Valine--pyruvate aminotransferase E3384_00910 ENOG4107T9C Alpha amylase catalytic region E3384_00915 ENOG4108UR8 BAX protein E3384_00920 ENOG4105T16 Transcriptional regulator (AraC family) E3384_00930 ENOG4105CMG Carbohydrate kinase E3384_00935 ENOG410688U Inner membrane protein yiaB E3384_00940 ENOG4105MEV Acyl-transferase E3384_00965 ENOG4105DQ6 Transposase E3384_00990 ENOG4105VEQ Cold shock protein E3384_00995 ENOG4105MVF Transcriptional regulator E3384_01000 ENOG4106JH6 (LipO)protein E3384_01005 ENOG4105C5I Dehydrogenase E3384_01010 ENOG4108ZG0 Ompa motb domain protein E3384_01015 ENOG4107QY8 reductase E3384_01020 ENOG4105HNP -acetyltransferase E3384_01025 ENOG4108R3E Dna-3-methyladenine glycosylase i E3384_01030 ENOG4105EAX Putative lipase E3384_01035 ENOG4106EAR Fimbrial protein E3384_01040 ENOG4108VCD Chaperone E3384_01045 ENOG4105CW0 outer membrane usher protein E3384_01050 ENOG4105MHR Fimbrial protein E3384_01055 ENOG4106UCC Fimbrial protein E3384_01060 ENOG4105DIJ Phosphoethanolamine transferase E3384_01075 ENOG4105CQ4 Transcriptional regulator E3384_01090 ENOG4105DEF Extracellular solute-binding protein, family 5 E3384_01095 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component E3384_01100 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component E3384_01105 ENOG4105C3U ABC transporter E3384_01110 ENOG4108JQ7 (ABC) transporter E3384_01115 ENOG4105C44 Serine transporter E3384_01130 ENOG4105D1V cellulose synthase operon protein YhjU E3384_01135 ENOG410675P Celllulose biosynthesis operon protein BcsF YhjT E3384_01145 ENOG410661M cytoplasmic protein E3384_01150 ENOG4105UTS cellulose synthase operon protein YhjQ E3384_01155 ENOG4107QZ7 Cellulose synthase catalytic subunit E3384_01160 ENOG4107EEX Cellulose synthase regulator protein E3384_01165 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) E3384_01170 ENOG4105EJG cellulose synthase E3384_01175 ENOG4105BZU Histidine kinase E3384_01185 ENOG4105CS0 peptidase E3384_01190 ENOG4107SS6 2-dehydro-3-deoxygluconokinase E3384_01195 ENOG4105CMB EAL domain-containing protein E3384_01200 ENOG41066T0 asmA family E3384_01205 ENOG4105CSH Transporter E3384_01210 ENOG4107H3J ribonuclease E3384_01215 ENOG4105CBN LysR family transcriptional regulator E3384_01220 ENOG4106S2D Transcriptional regulator E3384_01240 ENOG4105FDP GntR family transcriptional regulator E3384_01245 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine E3384_01250 ENOG4108KPW sugar kinase E3384_01255 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter E3384_01265 ENOG4105DC8 reductase E3384_01270 ENOG4105D6S protein involved in catabolism of external DNA E3384_01275 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase E3384_01280 ENOG4105DGW oligopeptidase A E3384_01285 ENOG4105FFN Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity) E3384_01290 ENOG4105DUX Transporter E3384_01295 ENOG4108M6U Universal stress protein A E3384_01305 ENOG4105CJ3 phosphate transporter E3384_01310 ENOG4105CBX hi0933 family E3384_01315 ENOG4105D0S secretion protein (HlyD E3384_01320 ENOG4105CJ1 ABC, transporter E3384_01325 ENOG4105CMI transporter E3384_01335 ENOG4107YAK holo-(acyl carrier protein) synthase 2 E3384_01340 ENOG4105DSF transport protein E3384_01350 ENOG4108W1V Lipoprotein E3384_01355 ENOG4105EX9 Membrane E3384_01365 ENOG4105C8Q Methyl-accepting chemotaxis E3384_01375 ENOG4107FS9 Membrane E3384_01385 ENOG4105MG3 Membrane E3384_01390 ENOG4106H78 methyltransferase E3384_01395 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) E3384_01400 ENOG4105CAK Cell division ATP-binding protein ftsE E3384_01405 ENOG4105CRP Part of the ABC transporter FtsEX involved in E3384_01415 ENOG4105CP9 extracellular ligand-binding receptor E3384_01425 ENOG4105U59 -acetyltransferase E3384_01430 ENOG4105CP9 extracellular ligand-binding receptor E3384_01435 ENOG4105C32 Amino acid ABC transporter (Permease) E3384_01440 ENOG4105CF8 branched-chain amino acid ABC transporter, permease E3384_01445 ENOG4105C0Z ABC transporter E3384_01450 ENOG4108IV0 ABC, transporter E3384_01460 ENOG4105BZ7 extracellular solute-binding protein family 1 E3384_01465 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component E3384_01475 ENOG4108IJ9 (ABC) transporter E3384_01480 ENOG4107T6V glycerophosphoryl diester phosphodiesterase E3384_01485 ENOG4105WC8 Conserved Protein E3384_01490 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) E3384_01495 ENOG41080QX K07048 phosphotriesterase-related protein E3384_01510 ENOG4108RVA ribokinase E3384_01515 ENOG4105WCN acetyltransferase E3384_01520 ENOG4105D9R oxidoreductase E3384_01525 ENOG4105C2I pirin domain protein E3384_01530 ENOG4105DIQ Transcriptional regulator E3384_01535 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family E3384_01540 ENOG4105C6Z Gluconate E3384_01550 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) E3384_01555 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) E3384_01575 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) E3384_01580 ENOG4107HP6 Transcriptional regulator E3384_01585 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) E3384_01590 ENOG4105C01 Dihydroxy-acid dehydratase E3384_01600 ENOG4105DCT glycerol dehydrogenase E3384_01615 ENOG4105C6V Glycerol-3-phosphate dehydrogenase E3384_01630 ENOG4105E98 transcriptional regulator DeoR family E3384_01635 ENOG4105CYB regulatoR E3384_01645 ENOG4105E0Y RtcB Protein E3384_01650 ENOG4105CKX Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP E3384_01660 ENOG4105VXN addiction module toxin, RelE StbE family E3384_01670 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) E3384_01675 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) E3384_01680 ENOG4105C6Z Gluconate E3384_01690 ENOG4105MJ2 Competence protein E3384_01700 ENOG4105DNE Transposase E3384_01715 ENOG4105XFK Ferrous iron transport protein A E3384_01720 ENOG4105BZM domain protein E3384_01725 ENOG4108RRZ Transcription elongation factor GreB E3384_01730 ENOG4105DPZ Two component transcriptional regulator (Winged helix family E3384_01735 ENOG4105E0F Histidine kinase E3384_01745 ENOG4108MAJ Membrane E3384_01750 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) E3384_01755 ENOG4105VEJ Heat shock protein E3384_01760 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 E3384_01765 ENOG4105DQY intracellular growth attenuator E3384_01770 ENOG4107RK2 ADP-ribose diphosphatase NudE E3384_01775 ENOG4108JQC penicillin-binding protein 1A E3384_01780 ENOG4108U1Q Pilus assembly protein E3384_01785 ENOG41065NF Fimbrial assembly family protein E3384_01790 ENOG4105XPX DNA utilization protein HofO E3384_01795 ENOG4105ITY Required for the use of extracellular DNA as a nutrient E3384_01800 ENOG4105E4G Type IV pilus E3384_01815 ENOG4105EGB membrane protein DamX E3384_01820 ENOG4105DFE Dna adenine methylase E3384_01825 ENOG4105DJV ribulose-phosphate 3-epimerase E3384_01830 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) E3384_01835 ENOG4105C31 Tryptophanyl-tRNA synthetase E3384_01840 ENOG4105VYH E3384_01845 ENOG4107EF2 surface-exposed virulence protein E3384_01855 ENOG4107V9H nitrite transporter E3384_01860 ENOG4105WZK nitrite reductase NADPH small subunit E3384_01865 ENOG4107QZF nitrite reductase NADPH large subunit E3384_01875 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) E3384_01880 ENOG4106195 uncharacterized protein yhfG E3384_01885 ENOG4105MZU cell filamentation protein E3384_01890 ENOG4105DDQ anthranilate synthase E3384_01895 ENOG4105C8Y Acetylornithine aminotransferase E3384_01900 ENOG410613R integral membrane protein, YccS YhfK family E3384_01910 ENOG4108UKZ OsmC family E3384_01915 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) E3384_01925 ENOG4105DNZ Alpha Beta Hydrolase E3384_01930 ENOG4105N0V mono-oxygenase ydhR E3384_01935 ENOG4108K70 Transcriptional regulator E3384_01940 ENOG4105C5H ABC transporter E3384_01955 ENOG4105VKU nucleicacid-binding protein E3384_01960 ENOG4108YZY peptidylprolyl cis-trans isomerase E3384_01970 ENOG4108V1T peptidylprolyl cis-trans isomerase E3384_01975 ENOG4105WWK YheO domain protein E3384_01990 ENOG4105YKK Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) E3384_02010 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) E3384_02015 ENOG4105W53 bacterioferritin-associated ferredoxin E3384_02020 ENOG4108UQY Iron-storage protein E3384_02025 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) E3384_02040 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) E3384_02055 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) E3384_02060 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) E3384_02065 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) E3384_02075 ENOG41083MP 50s ribosomal protein l29 E3384_02085 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) E3384_02090 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) E3384_02105 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) E3384_02115 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) E3384_02120 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) E3384_02125 ENOG4105VPB 50S ribosomal protein L30 E3384_02130 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) E3384_02135 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) E3384_02140 ENOG41067V7 50S ribosomal protein L36 E3384_02160 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) E3384_02170 ENOG4105VTS DnaJ-like, subfamily C E3384_02175 ENOG4105W1Y Transcriptional regulator E3384_02180 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system E3384_02190 ENOG4105C1A potassium transporter peripheral membrane E3384_02210 ENOG4105C79 DNA protecting protein DprA E3384_02220 ENOG4108WI1 Dna topoisomerase E3384_02235 ENOG4105SG3 Protein of unknown function (DUF1488) E3384_02240 ENOG4108Z0R Transferase E3384_02275 ENOG4105XCM membrane LIPOPROTEIN E3384_02280 ENOG4105BZS acriflavin resistance protein E3384_02285 ENOG4105C1P efflux transporter, rnd family, mfp subunit E3384_02290 ENOG4108XG4 DNA-binding transcriptional regulator E3384_02295 ENOG4105BZU Histidine kinase E3384_02300 ENOG41061ME transport protein E3384_02305 ENOG4105CEC DNA methylase N-4 N-6 E3384_02310 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) E3384_02315 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) E3384_02330 ENOG4108IA2 Sodium pantothenate symporter E3384_02335 ENOG4105RG0 Membrane E3384_02340 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase E3384_02345 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein E3384_02360 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family E3384_02365 ENOG41062P1 Diguanylate cyclase phosphodiesterase E3384_02370 ENOG4105DFF Rod shape-determining protein mreb E3384_02375 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) E3384_02380 ENOG4105VQ7 Rod shape-determining protein MreD E3384_02390 ENOG4105C03 ribonuclease E3384_02395 ENOG4105QD6 exported protein E3384_02400 ENOG4105D1U peptidase U62 modulator of DNA gyrase E3384_02405 ENOG4105CR8 Transcriptional regulator E3384_02410 ENOG4105ZQC membrane protein AaeX E3384_02425 ENOG4105UNR (Barnase) inhibitor E3384_02430 ENOG4105RID UPF0379 protein yhcN E3384_02435 ENOG4105RID UPF0379 protein yhcN E3384_02450 ENOG4105FDP GntR family transcriptional regulator E3384_02460 ENOG4105C8P )-transporter E3384_02465 ENOG4106DSS Tartrate dehydratase subunit alpha E3384_02470 ENOG4107GFK fumarate E3384_02480 ENOG4107QSA Oxaloacetate decarboxylase E3384_02485 ENOG4105D9Q decarboxylase (Beta subunit) E3384_02500 ENOG4105C0H protease E3384_02505 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III E3384_02510 ENOG4105D6Z AFG1 family ATPase E3384_02535 ENOG4107MKT Stringent starvation protein a E3384_02540 ENOG4105KB2 stringent starvation protein b E3384_02570 ENOG4108R66 Conserved Protein E3384_02575 ENOG4105DZC cytosine deaminase E3384_02580 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin E3384_02585 ENOG4105DFS Conserved Protein E3384_02590 ENOG4105BZ8 glutamate synthase E3384_02595 ENOG4105CBC glutamate synthase E3384_02600 ENOG4105N5T Radical SAM Protein E3384_02605 ENOG4105BZU Histidine kinase E3384_02610 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain E3384_02620 ENOG4108NIH transferase activity, transferring phosphorus-containing groups E3384_02625 ENOG41080Z8 PHOSPHOCARRIER protein E3384_02635 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN E3384_02640 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA E3384_02645 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) E3384_02650 ENOG4108IUZ ABC transporter E3384_02655 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA E3384_02660 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) E3384_02665 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase E3384_02670 ENOG4105C2X Arabinose 5-phosphate isomerase E3384_02675 ENOG4105FEU K -dependent Na -Ca exchanger E3384_02680 ENOG4105DHJ ABC, transporter E3384_02685 ENOG4105CY3 ABC transporter, permease E3384_02690 ENOG4107PE3 Mammalian cell entry related domain protein E3384_02695 ENOG4105E3I toluene tolerance E3384_02700 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane E3384_02705 ENOG4105VFK BolA family E3384_02715 ENOG4105HVQ Regulatory factor of maltose metabolism E3384_02720 ENOG4105EAH synthase E3384_02735 ENOG4105QYV Membrane E3384_02745 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase E3384_02750 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) E3384_02755 ENOG4105HBR Rna-binding protein E3384_02760 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) E3384_02765 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) E3384_02770 ENOG4105EEI dihydropteroate synthase E3384_02810 ENOG4105CHV Transcription elongation factor NusA E3384_02850 ENOG4105C1J atp-dependent rna helicase E3384_02855 ENOG4105CIC tryptophan-specific transport protein E3384_02865 ENOG4105F7V ErfK ybiS ycfS ynhG family protein E3384_02870 ENOG4105DEN Luciferase family E3384_02875 ENOG4106RZ4 Peptidase U32 E3384_02880 ENOG4105CFP Peptidase U32 E3384_02885 ENOG4105XPQ lipid carrier protein E3384_02890 ENOG4108YYD acetyltransferase E3384_02905 ENOG4107R7Y intracellular protease Pfpi family E3384_02910 ENOG4105K4T epimerase E3384_02915 ENOG4105W4M Transport-associated protein E3384_02935 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) E3384_02945 ENOG4107WTH Galactitol-1-phosphate dehydrogenase E3384_02950 ENOG4105DT3 PTS system, galactitol-specific IIc component E3384_02955 ENOG41090UW PTS System E3384_02960 ENOG41082GB PTS system galactitol-specific transporter subunit IIA E3384_02970 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein E3384_02975 ENOG4105DM4 PTS System E3384_02980 ENOG4105DE4 1-phosphofructokinase E3384_02985 ENOG4105D2N Aldolase E3384_02990 ENOG4105MVE transcriptional regulator E3384_02995 ENOG4107UEK pfkb domain protein E3384_03000 ENOG4105CTX dehydratase E3384_03010 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase E3384_03015 ENOG4105BZW Glycerate kinase E3384_03025 ENOG410811B TRANSCRIPTIONal E3384_03030 ENOG4105C7B Threonine dehydratase E3384_03045 ENOG4105C6N Formate acetyltransferase E3384_03050 ENOG4105EJQ L-serine dehydratase E3384_03055 ENOG4105C44 Serine transporter E3384_03065 ENOG4106D80 Uncharacterized protein YhaL E3384_03070 ENOG4108CNN domain protein E3384_03075 ENOG4105CWB LysR family transcriptional Regulator E3384_03080 ENOG4105KAF membrAne E3384_03085 ENOG4105CHF Glutathione S-transferase E3384_03090 ENOG4108VBZ doxx family E3384_03095 ENOG4105YJD E3384_03100 ENOG41090KG Inner membrane protein YqjE E3384_03105 ENOG4105NE1 Conserved Protein E3384_03110 ENOG4105WAY exported protein E3384_03120 ENOG4106W5V Membrane E3384_03130 ENOG4105DU1 integral membrane protein, terc E3384_03135 ENOG4105EE0 oxidoreductase E3384_03140 ENOG4108UB4 uncharacterized protein ygjQ E3384_03145 ENOG4108VKG metal-dependent hydrolase E3384_03155 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase E3384_03165 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor E3384_03165 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor E3384_03170 ENOG4105C8Q Methyl-accepting chemotaxis E3384_03175 ENOG4105NTW Transcriptional regulator E3384_03180 ENOG4105Q26 Siderophore-interacting protein E3384_03195 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) E3384_03200 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) E3384_03205 ENOG4105VCC 30S ribosomal protein S21 E3384_03230 ENOG4107ZVW dihydroneopterin aldolase E3384_03245 ENOG4106MWK domain protein E3384_03250 ENOG4105I7R Adenylate cyclase E3384_03270 ENOG4107S78 Band 7 protein E3384_03275 ENOG4105PV3 Inner membrane protein yqiJ E3384_03285 ENOG4105W0Z cytoplasmic protein E3384_03305 ENOG4108MR7 Arylsulfotransferase E3384_03315 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b E3384_03320 ENOG4106032 Glutathionylspermidine synthase E3384_03335 ENOG41087AY ADP-Ribose pyrophosphatase E3384_03340 ENOG4108SX3 cytoplasmic protein E3384_03345 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) E3384_03350 ENOG4105IPS esterase E3384_03355 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) E3384_03360 ENOG4105VRH Antibiotic biosynthesis monooxygenase E3384_03365 ENOG4105NF4 modulator of drug activity E3384_03370 ENOG4105DHQ Histidine kinase E3384_03375 ENOG4105XJC Two component transcriptional regulator (Winged helix family E3384_03380 ENOG4105H4F exported protein E3384_03385 ENOG4105F4I Transcriptional regulator E3384_03390 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) E3384_03395 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase E3384_03400 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) E3384_03405 ENOG4105CG6 trap dicarboxylate transporter dctm subunit E3384_03415 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit E3384_03420 ENOG4105CCT upf0313 protein E3384_03435 ENOG4107QPK )-transporter E3384_03440 ENOG4105CV8 reductase E3384_03445 ENOG4108I6A alcohol dehydrogenase E3384_03450 ENOG4105CF7 AraC family transcriptional regulator E3384_03455 ENOG4108K81 inner membrane protein YghB E3384_03460 ENOG4105C28 cystathionine E3384_03465 ENOG4105CWK Biopolymer transport protein, ExbB E3384_03470 ENOG4108ZZF transport protein (ExbD) E3384_03475 ENOG4105CYX Short-chain dehydrogenase reductase Sdr E3384_03500 ENOG4105C8Q Methyl-accepting chemotaxis E3384_03505 ENOG410900S Protein of unknown function (DUF2623) E3384_03510 ENOG4105E3S small subunit E3384_03515 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein E3384_03520 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit E3384_03525 ENOG4105DPX Hydrogenase, large subunit E3384_03530 ENOG4108USZ hydrogenase E3384_03535 ENOG4108WGS hydrogenase 2-specific chaperone E3384_03540 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) E3384_03545 ENOG41082MF Hydrogenase assembly chaperone hypC hupF E3384_03550 ENOG4105S10 periplasmic binding protein E3384_03555 ENOG4108VJC ABC transporter, periplasmic molybdate-binding protein E3384_03560 ENOG4105CYM Glutathione S-transferase E3384_03565 ENOG4106032 Glutathionylspermidine synthase E3384_03580 ENOG4105DEI Mannitol dehydrogenase E3384_03590 ENOG4105DPW Major facilitator superfamily MFS_1 E3384_03615 ENOG4105C26 Dehydrogenase E3384_03620 ENOG4105CJP fad dependent oxidoreductase E3384_03630 ENOG4105CUB amino acid E3384_03640 ENOG4108UAJ Transcriptional regulator E3384_03650 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) E3384_03660 ENOG4105CI0 Citrate lyase E3384_03665 ENOG4105DJG MaoC domain protein dehydratase E3384_03670 ENOG4105CYC Transferase E3384_03675 ENOG4109025 Glyoxalase Bleomycin resistance protein (Dioxygenase E3384_03685 ENOG4108UQV Membrane E3384_03690 ENOG4105CXN decarboxylase E3384_03695 ENOG4105EAA nucleoside E3384_03710 ENOG4105CEN a g-specific adenine glycosylase E3384_03720 ENOG41090ED Protein with unknown function (DUF469) E3384_03725 ENOG4105K33 Periplasmic Protein E3384_03730 ENOG4105HDK L-asparaginase E3384_03735 ENOG4106MH3 alpha helix chain E3384_03740 ENOG4105CSA Coproporphyrinogen iii oxidase E3384_03755 ENOG4108VIA integral membrane protein E3384_03760 ENOG4105DFA alanine racemase domain protein E3384_03765 ENOG4105CZX twitching motility protein E3384_03785 ENOG4105D7Z glutathione synthase E3384_03790 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) E3384_03795 ENOG4105RWS endonuclease I E3384_03805 ENOG4107QNK )-transporter E3384_03825 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) E3384_03835 ENOG4107YCY Transcriptional regulator E3384_03845 ENOG4105DEI Mannitol dehydrogenase E3384_03850 ENOG4105CPQ Dehydrogenase E3384_03855 ENOG4105DG4 malate L-lactate dehydrogenase E3384_03860 ENOG4108R66 Conserved Protein E3384_03865 ENOG4108MXF Alpha Beta Hydrolase E3384_03875 ENOG4108K0D peptidase, M48 E3384_03880 ENOG4105CV1 Transketolase (EC 2.2.1.1) E3384_03885 ENOG4108JJB ABC transporter E3384_03890 ENOG4108JJB ABC transporter E3384_03920 ENOG4105D2N Aldolase E3384_03925 ENOG4105D64 Mechanosensitive ion channel E3384_03935 ENOG4105MPN Membrane E3384_03950 ENOG4108JQ1 Dehydrogenase E3384_03955 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase E3384_03975 ENOG4107RAQ aminopeptidase E3384_03980 ENOG4105D0A hydroxylase E3384_03985 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family E3384_04015 ENOG4105CS2 ec 3.2.1.21 E3384_04025 ENOG4108UT2 hemolysin iii E3384_04040 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB E3384_04045 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) E3384_04050 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) E3384_04055 ENOG4105T95 Thiol disulfide interChange protein E3384_04060 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) E3384_04070 ENOG4105CRK lysyL-tRNA synthetase E3384_04085 ENOG4108K5P (LipO)protein E3384_04095 ENOG4105DFP Integrase E3384_04160 ENOG4105CAU Arsenical resistance protein, ArsH E3384_04195 ENOG4108TTM chaperone E3384_04210 ENOG4105KT7 mgtC SapB transporter E3384_04255 ENOG4105CVJ phosphoglycerate mutase E3384_04260 ENOG4105EUZ Beta-lactamase domain protein E3384_04265 ENOG4105EGS Mechanosensitive ion channel E3384_04270 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation E3384_04275 ENOG4108MXD gtp-binding protein E3384_04280 ENOG4108KZE transcriptional regulator E3384_04305 ENOG4106H6R UPF0380 protein E3384_04310 ENOG4105MFG Antirestriction protein E3384_04315 ENOG4108XS9 dna repair protein E3384_04320 ENOG4105ZS6 Protein of unknown function (DUF987) E3384_04325 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles E3384_04330 ENOG4108X3P Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures E3384_04350 ENOG4108T1M outer membrane protein x E3384_04370 ENOG4106P2F Pfam:Pili_assembly_C E3384_04400 ENOG4108MHD transport protein E3384_04410 ENOG4105C5Q Transcriptional regulator E3384_04415 ENOG4105CHU acetyl-coa acetyltransferase E3384_04425 ENOG4105CHR reductase E3384_04430 ENOG4107QNK )-transporter E3384_04440 ENOG4105RQF LysR family Transcriptional regulator E3384_04445 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) E3384_04450 ENOG4105DDV Transcriptional regulator (LacI family E3384_04470 ENOG4105CPC Aldo Keto reductase E3384_04475 ENOG4105SUV lipoprotein YgdR E3384_04480 ENOG4105EE5 Membrane protein terC E3384_04495 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase E3384_04515 ENOG4105IPU prepilin peptidase dependent protein A E3384_04520 ENOG4105JCS prepilin peptidase dependent protein E3384_04525 ENOG4105SEN Protein of unknown function (DUF2509) E3384_04530 ENOG4105RVB Prepilin peptidase dependent protein c E3384_04535 ENOG4105DSY exodeoxyribonuclease V, gamma E3384_04540 ENOG4107QXK peptidase E3384_04545 ENOG4107QKA exodeoxyribonuclease V beta E3384_04550 ENOG4107QYX exodeoxyribonuclease v alpha E3384_04555 ENOG4108EKC n-acetylglutamate synthase E3384_04560 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase E3384_04575 ENOG4105CA3 membrane-bound lytic murein transglycosylase E3384_04580 ENOG4105CUZ uba thif-type nad fad binding protein E3384_04585 ENOG4105FR1 rard protein E3384_04590 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) E3384_04595 ENOG4105C9B Cysteine desulfurase E3384_04600 ENOG4105M5B (LipO)protein E3384_04605 ENOG4105ETT transcriptional Regulator, LysR family E3384_04610 ENOG4105M08 Membrane E3384_04620 ENOG4107EDW L-fucose operon activator E3384_04630 ENOG4105CMG Carbohydrate kinase E3384_04640 ENOG4105EDR glucose galactose transporter E3384_04645 ENOG4107W7X Aldolase E3384_04650 ENOG4105C0A alcohol dehydrogenase E3384_04660 ENOG4105EJQ L-serine dehydratase E3384_04665 ENOG4105C44 Serine transporter E3384_04670 ENOG4105EWT decarboxylase family E3384_04690 ENOG4105WP7 tRNA pseudouridine synthase C E3384_04695 ENOG4105DR9 pseudouridine synthase E3384_04700 ENOG4105QDK Flavodoxin E3384_04710 ENOG4105DJB Major Facilitator Superfamily E3384_04715 ENOG4105EQX glucarate dehydratase E3384_04720 ENOG4105EQX glucarate dehydratase E3384_04725 ENOG4105BZW Glycerate kinase E3384_04730 ENOG4105BZU Histidine kinase E3384_04735 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) E3384_04740 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) E3384_04745 ENOG4105X54 addiction module antidote protein E3384_04775 ENOG4105NEV Fimbrial E3384_04780 ENOG4108FZ9 Chaperone E3384_04785 ENOG4106PG1 outer membrane usher protein E3384_04795 ENOG4105DXN mazG family E3384_04810 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) E3384_04815 ENOG4108H5C Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) E3384_04820 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase E3384_04845 ENOG4105DTT CRISPR-associated helicase, cas3 E3384_04850 ENOG4105CYR Crispr-associated protein, cse1 family E3384_04860 ENOG41060M0 Crispr-associated protein, cse4 family E3384_04865 ENOG4108VWQ crispr-associated protein E3384_04875 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) E3384_04880 ENOG4105PWE CRISPR-associated protein cas2 E3384_04885 ENOG4108MXK alkaline phosphatase isozyme conversion E3384_04905 ENOG4105N0Z inner membrane protein ygbE E3384_04920 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) E3384_04940 ENOG4108K5P (LipO)protein E3384_04950 ENOG4105KZM cytoplasmic protein E3384_04955 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) E3384_04960 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase E3384_04970 ENOG4105MVE transcriptional regulator E3384_04980 ENOG4105G63 Type III effector Hrp-dependent E3384_04990 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) E3384_04995 ENOG4105EXW epimerase dehydratase E3384_05000 ENOG4105C6Z Gluconate E3384_05005 ENOG4105JQN Transcriptional regulator E3384_05010 ENOG4105C0R drug resistance transporter emrb qaca subfamily E3384_05045 ENOG4105MEW serine threonine protein phosphatase E3384_05090 ENOG41090HZ type iii secretion E3384_05095 ENOG4105K44 type iii secretion E3384_05100 ENOG4108N8R Invasion protein E3384_05105 ENOG4108HR8 type iii secretion E3384_05110 ENOG4105REY Chaperone specialized in the storage of effectors within the bacterial cytoplasm, maintaining them in a secretion-competent state, and allowing their immediate delivery to target cells upon contact of the bacterium with the host cells. Has been shown to chaperone E3384_05115 ENOG4108JIR Flagellum-specific ATP synthase E3384_05120 ENOG41077MC Secretory protein (Associated with virulence) E3384_05125 ENOG41078G4 surface presentation of E3384_05130 ENOG4105T85 surface presentation of antigens protein E3384_05135 ENOG41075IY surface presentation of antigens protein SpaP E3384_05145 ENOG4108TN6 type iii secretion E3384_05150 ENOG4108M6W surface presentation of antigens protein SpaS E3384_05170 ENOG4105IBT Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of SipA, SipB, and SipC E3384_05180 ENOG41079WB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) E3384_05195 ENOG410641W Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities. After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE. This function is independent of its tyrosine phosphatase activity, which remains unclear E3384_05200 ENOG4105FTC Lytic transglycosylase catalytic E3384_05205 ENOG4108YAB Invasion protein E3384_05215 ENOG4108RC9 Type III secretion system protein E3384_05220 ENOG4105Y7Q type iii secretion E3384_05225 ENOG4106BTR E3384_05230 ENOG4108RBT type iii secretion E3384_05265 ENOG4105CC5 ABC transporter E3384_05270 ENOG4105CC5 ABC transporter E3384_05275 ENOG4105DIK (ABC) transporter E3384_05285 ENOG4105VXR cytoplasmic protein E3384_05295 ENOG4105C45 hydrogenase expression formation protein (HypE) E3384_05300 ENOG4105CQS hydrogenase expression formation protein HypD E3384_05305 ENOG41083WG hydrogenase assembly chaperone E3384_05310 ENOG4107RSS Hydrogenase accessory protein HypB E3384_05315 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) E3384_05320 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA E3384_05325 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) E3384_05330 ENOG4107R30 NADH dehydrogenase E3384_05335 ENOG4107TDF Formate hydrogenlyase subunit 4 E3384_05340 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) E3384_05345 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit E3384_05350 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit E3384_05355 ENOG4105I6X formate hydrogenlyase maturation E3384_05360 ENOG4108MG9 hydrogenase 3 maturation protease E3384_05370 ENOG4108RC0 Electron transport protein E3384_05375 ENOG4105C8H hydrogenase maturation protein Hypf E3384_05395 ENOG4105C2X Arabinose 5-phosphate isomerase E3384_05400 ENOG410804X Transcriptional regulator E3384_05405 ENOG4105J92 DNA-binding transcriptional activator GutM E3384_05410 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase E3384_05415 ENOG4105VI0 Pts system, glucitol sorbitol-specific E3384_05420 ENOG4105DZY Pts system, glucitol sorbitol-specific E3384_05425 ENOG410787A Pts system, glucitol sorbitol-specific E3384_05430 ENOG4105CVE Lytic murein transglycosylase E3384_05440 ENOG4107TH8 cina domain protein E3384_05460 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) E3384_05465 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) E3384_05495 ENOG4107VXZ Hydrolase E3384_05500 ENOG4105W39 Membrane E3384_05520 ENOG4105C0R drug resistance transporter emrb qaca subfamily E3384_05525 ENOG4105CW7 secretion protein, HlyD family E3384_05530 ENOG4105NTK Transcriptional repressor Mpra E3384_05540 ENOG4105GIJ Glycine betaine E3384_05545 ENOG4108HQS Glycine betaine E3384_05550 ENOG4108IJ7 Glycine betaine E3384_05555 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) E3384_05560 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) E3384_05570 ENOG4105WAZ (Glutaredoxin-like protein) NrdH E3384_05580 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) E3384_05590 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) E3384_05595 ENOG4108WMJ Protein of unknown function (DUF2002) E3384_05600 ENOG4108RNS Exports L-alanine (By similarity) E3384_05610 ENOG4108X73 DNA- binding protein E3384_05620 ENOG4108V62 Rhodanese domain protein E3384_05625 ENOG41080HT Transcriptional regulator, arsr family E3384_05630 ENOG4105VPI YqaE family transport protein E3384_05640 ENOG4109066 lysm domain bon superfamily protein E3384_05645 ENOG4108PVQ transcriptional regulator E3384_05650 ENOG4105C85 amino acid E3384_05655 ENOG4108JPW Aminotransferase E3384_05660 ENOG4105C26 Dehydrogenase E3384_05665 ENOG4105D5U fad dependent oxidoreductase E3384_05695 ENOG4105DHQ Histidine kinase E3384_05715 ENOG4108MJ5 VirK protein E3384_05720 ENOG4105VRE Pentapeptide repeat protein E3384_05730 ENOG4107RNH Outer membrane receptor FepA E3384_05735 ENOG4105NIV Esterase E3384_05745 ENOG4105BZ1 (ABC) transporter E3384_05760 ENOG4108C33 Resolvase E3384_05765 ENOG4105I03 Flagellin E3384_05810 ENOG4105DFP Integrase E3384_05825 ENOG4105BZ1 (ABC) transporter E3384_05845 ENOG4108Z1B Cyclase dehydrase E3384_05855 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) E3384_05860 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) E3384_05880 ENOG4108JU6 CBS domain protein E3384_05885 ENOG4106KVJ cytochrome C assembly protein E3384_05890 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY E3384_05915 ENOG4108KHX Diguanylate cyclase E3384_05920 ENOG4108WS1 E3384_05925 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) E3384_05930 ENOG4105EHE chorismate mutase- prephenate dehydrogenase E3384_05940 ENOG4105CQC Prephenate dehydratase E3384_05950 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA E3384_05960 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane E3384_05965 ENOG4105C34 Pseudouridine synthase E3384_05970 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase E3384_05975 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit E3384_06005 ENOG4105CSH Transporter E3384_06010 ENOG4105T42 (LipO)protein E3384_06015 ENOG4105JIM Phosphatidylserine synthase E3384_06020 ENOG4105CD5 CoA-binding domain protein E3384_06025 ENOG4106IUH DTW domain containing protein E3384_06030 ENOG4105K63 Thioredoxin E3384_06035 ENOG4105EIB trna rrna methyltransferase E3384_06055 ENOG41090KR LysR family transcriptional Regulator E3384_06060 ENOG4105C1J atp-dependent rna helicase E3384_06070 ENOG4108IYU L-aspartate oxidase E3384_06100 ENOG4105WMJ Positive regulator of sigma E, RseC MucC E3384_06110 ENOG4105C3F Signal peptidase i E3384_06130 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) E3384_06140 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding E3384_06145 ENOG4105DND Transcriptional regulator E3384_06150 ENOG4105FCD Major Facilitator E3384_06155 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) E3384_06160 ENOG4106G6Q Transcriptional regulator E3384_06175 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB E3384_06180 ENOG4108Z6B deaminase E3384_06185 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) E3384_06195 ENOG4108ETH Formylglycinamide ribotide synthetase E3384_06200 ENOG4107WP9 Histidine kinase E3384_06205 ENOG4108SKK alpha helix protein E3384_06210 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family E3384_06215 ENOG4108YZA Nitrogen regulatory protein pii E3384_06220 ENOG4105DUX Transporter E3384_06225 ENOG4105CXN decarboxylase E3384_06230 ENOG4105D5Q Arginine ornithine antiporter E3384_06235 ENOG4108M3R transcriptional activator CadC E3384_06245 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) E3384_06250 ENOG4105D8G Major Facilitator superfamily E3384_06255 ENOG4108MN2 Stationary phase inducible protein CsiE E3384_06265 ENOG4105D7X high-affinity nickel-transporter E3384_06270 ENOG410810Y Sulfite reductase E3384_06275 ENOG4107SHJ sulfite reductase subunit b E3384_06280 ENOG4105D5B Sulfite reductase, subunit A E3384_06285 ENOG4107XM9 (LipO)protein E3384_06290 ENOG4105ECY inositol monophosphatase E3384_06310 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins E3384_06330 ENOG4108ZIT Ferredoxin, 2FE-2S E3384_06335 ENOG4105WVQ Fe-S assembly protein IscX E3384_06350 ENOG4105YYA enhanced serine sensitivity protein SseB E3384_06360 ENOG4105KHC sulfurtransferase E3384_06365 ENOG4105DN3 alpha-2-macroglobulin domain protein E3384_06370 ENOG4108JQB penicillin-binding protein 1C E3384_06375 ENOG4107QY8 reductase E3384_06380 ENOG4105QAX Iron-sulfur E3384_06420 ENOG4105N21 Membrane E3384_06425 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) E3384_06435 ENOG4105VPD cellular component movement E3384_06475 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) E3384_06500 ENOG41062G3 Protein of unknown function (DUF2633) E3384_06510 ENOG4105BZU Histidine kinase E3384_06515 ENOG4105C9X ppx gppa phosphatase E3384_06520 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) E3384_06525 ENOG4108V3E phosphoribosylglycinamide formyltransferase E3384_06540 ENOG4105C2W permease E3384_06550 ENOG4105K89 arsenate reductase E3384_06555 ENOG4105ERG peptidase m48, ste24p E3384_06560 ENOG4105C02 permease E3384_06565 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR E3384_06570 ENOG4107QQ0 gntp family E3384_06575 ENOG4105BZW Glycerate kinase E3384_06580 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen E3384_06585 ENOG4105RH4 Glycine cleavage system transcriptional repressor E3384_06590 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) E3384_06595 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) E3384_06605 ENOG4105CGZ zinc metallopeptidase E3384_06610 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) E3384_06620 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) E3384_06625 ENOG4105KUZ arsenate reductase E3384_06635 ENOG4105BZS acriflavin resistance protein E3384_06640 ENOG4105BZU Histidine kinase E3384_06645 ENOG4105BZ8 glutamate synthase E3384_06655 ENOG4107VIJ nudix hydrolase E3384_06660 ENOG4108PVD exported protein E3384_06670 ENOG4105CV1 Transketolase (EC 2.2.1.1) E3384_06680 ENOG4105C6K Malic enzyme E3384_06685 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place E3384_06690 ENOG4106S4J ethanolamine utilization protein EutP E3384_06695 ENOG4105NDK ethanolamine utilization protein E3384_06700 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase E3384_06705 ENOG4108IJ2 phosphate acetyltransferase E3384_06710 ENOG4105KNY Microcompartments protein E3384_06715 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml E3384_06720 ENOG4108EKI Dehydrogenase E3384_06725 ENOG4107RWI ethanolamine utilization protein eutJ E3384_06730 ENOG4105C0A alcohol dehydrogenase E3384_06735 ENOG4105ENY Ethanolamine utilization protein eutH E3384_06740 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase E3384_06745 ENOG4105CPD ethanolamine ammonia-lyase E3384_06755 ENOG4106D67 ethanolamine utilization protein E3384_06760 ENOG4108X49 Ethanolamine utilization protein EutK E3384_06765 ENOG4108K3Z AraC family transcriptional regulator E3384_06770 ENOG4107H8F E3384_06785 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase E3384_06795 ENOG4105QZU Inner membrane protein YfeZ E3384_06800 ENOG4105E7K (LipO)protein E3384_06805 ENOG4105EZR dyp-type peroxidase family protein E3384_06810 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr E3384_06815 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein E3384_06820 ENOG4108I5D sulfate abc transporter E3384_06825 ENOG4105ECW sulfate abc transporter E3384_06830 ENOG4108IJ6 ABC transporter E3384_06835 ENOG4105C6T cysteine synthase E3384_06845 ENOG4105M0Y E3384_06850 ENOG41089BK Glutamine amido-transferase E3384_06855 ENOG4105CSW GntR family transcriptional regulator E3384_06870 ENOG4105C5Y PTS System E3384_06880 ENOG4105KZ7 phosphocarrier protein hpr E3384_06885 ENOG4105C6T cysteine synthase E3384_06905 ENOG4105VRT cytoplasmic protein E3384_06910 ENOG4105DHU Bile acid E3384_06915 ENOG4108M0I Transcriptional regulator E3384_06920 ENOG4108NFH Sugar hydrolase E3384_06925 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) E3384_06930 ENOG4105EAA nucleoside E3384_06940 ENOG4105CN8 Transcriptional regulator E3384_06965 ENOG4105GXM Putative transcription regulator (DUF1323) E3384_06970 ENOG4105HZG regulatoR E3384_06985 ENOG4108KMM Diguanylate cyclase E3384_06990 ENOG4105D9N nucleoside E3384_07000 ENOG4109076 Conserved Protein E3384_07005 ENOG4105CPC Aldo Keto reductase E3384_07010 ENOG4107RA9 decarboxylase E3384_07025 ENOG4105CHM Aminotransferase E3384_07035 ENOG4105D1S lipid A biosynthesis E3384_07040 ENOG4105W9M Membrane E3384_07045 ENOG4105CXY transporter E3384_07050 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC E3384_07060 ENOG4107TXD phosphoglycerate transport system transcriptional regulatory protein pgta E3384_07065 ENOG4108NC2 Outer membrane protease E3384_07075 ENOG4105S64 Formate nitrite transporter E3384_07080 ENOG410903C (LipO)protein E3384_07085 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation E3384_07090 ENOG4105KZW UPF0381 protein E3384_07105 ENOG4108BY2 phosphohistidine phosphatase E3384_07115 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) E3384_07130 ENOG4105EJ9 Membrane E3384_07135 ENOG4108BPE -transporting atpase E3384_07140 ENOG4105MH2 YfcL protein E3384_07145 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) E3384_07150 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) E3384_07170 ENOG4105R8V Transcriptional regulator E3384_07185 ENOG4106WZ1 flagella biosynthesis regulator E3384_07195 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) E3384_07205 ENOG4105DQR SNARE associated Golgi E3384_07215 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase E3384_07220 ENOG4108S3P Sporulation domain protein E3384_07225 ENOG4105E96 Colicin v production protein E3384_07230 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase E3384_07235 ENOG4108JUB Transcriptional regulator E3384_07245 ENOG4105E5D amino acid E3384_07250 ENOG4106M28 alanine racemase domain protein E3384_07260 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase E3384_07265 ENOG4105E89 ABC transporter E3384_07270 ENOG4105E89 ABC transporter E3384_07275 ENOG4105DSP amino acid AbC transporter E3384_07280 ENOG4106YG3 ABC transporter E3384_07285 ENOG4108JEH abc transporter atp-binding protein E3384_07290 ENOG4105ECP epimerase E3384_07295 ENOG4105CYM Glutathione S-transferase E3384_07300 ENOG4108SHQ Glutathione S-transferase E3384_07305 ENOG4108RE9 Phosphodiesterase E3384_07310 ENOG4105PTV Nudix Hydrolase E3384_07315 ENOG4105K2J Transcriptional regulator E3384_07320 ENOG4106ETB IIa component E3384_07330 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC E3384_07335 ENOG4108HHA Transketolase E3384_07340 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) E3384_07345 ENOG4105CSX c4-dicarboxylate anaerobic carrier E3384_07350 ENOG4105C6K Malic enzyme E3384_07355 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) E3384_07370 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 E3384_07375 ENOG4107QWE )-transporter E3384_07390 ENOG4105CHM Aminotransferase E3384_07395 ENOG4107NQ8 LysR family Transcriptional regulator E3384_07420 ENOG4105GKE subunit e E3384_07425 ENOG4107QIZ NADH dehydrogenase E3384_07430 ENOG4107R0R NADH dehydrogenase subunit g E3384_07445 ENOG4107UFS subunit j E3384_07455 ENOG4105D65 subunit l E3384_07460 ENOG4105C8S subunit m E3384_07470 ENOG4107R88 Chemotaxis protein (CheV) E3384_07480 ENOG4107YB6 acetyltransferase, (GNAT) family E3384_07485 ENOG4105TNS Conserved Protein E3384_07490 ENOG4105E4F Isochorismate synthase E3384_07505 ENOG4108IPT Naphthoate synthase E3384_07515 ENOG4105CEY Amp-dependent synthetase and ligase E3384_07520 ENOG4106GZG polymyxin resistance protein B E3384_07535 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) E3384_07570 ENOG4108UII YfaZ family E3384_07580 ENOG4107258 Transcriptional regulator E3384_07590 ENOG4105CSP Major Facilitator Superfamily E3384_07610 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) E3384_07620 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A E3384_07625 ENOG4105CXY transporter E3384_07630 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase E3384_07635 ENOG4105GZI Transcriptional regulator E3384_07640 ENOG4105CZM Major Facilitator E3384_07645 ENOG4105XPH Ferredoxin E3384_07650 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) E3384_07655 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) E3384_07675 ENOG4105CXK mandelate racemase muconate lactonizing E3384_07680 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) E3384_07685 ENOG4105BZU Histidine kinase E3384_07690 ENOG41068CG regulatoR E3384_07695 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC E3384_07700 ENOG4105FCK Membrane E3384_07705 ENOG4105CJ2 (LipO)protein E3384_07710 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) E3384_07715 ENOG4105CF1 Alkylated DNA repair protein E3384_07720 ENOG4105IBP Cyclic peptide transporter E3384_07730 ENOG4108ZNS ferredoxin-type protein NapF E3384_07735 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase E3384_07745 ENOG4108BGM Quinol dehydrogenase periplasmic component E3384_07750 ENOG4105GXZ Ferredoxin-type protein NapH E3384_07755 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) E3384_07760 ENOG4105CUW cytochrome C-TYPE protein E3384_07770 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) E3384_07775 ENOG41060IM Heme exporter protein E3384_07780 ENOG4105X3C heme exporter protein E3384_07790 ENOG4105DA4 cytochrome c-type biogenesis protein E3384_07795 ENOG4107QX9 Thiol disulfide interChange protein E3384_07800 ENOG4105KWW Biogenesis protein E3384_07805 ENOG4105WH1 Two component transcriptional regulator luxr family E3384_07820 ENOG4108X9F tail fiber protein E3384_07845 ENOG4105E68 Sulfatase E3384_07870 ENOG4105CFI type iii restriction protein res subunit E3384_07875 ENOG4105I08 Pseudouridine synthase E3384_07880 ENOG4105C2C drug resistance transporter, Bcr CflA E3384_07885 ENOG4105HG6 E3384_07890 ENOG4108JQ5 ABC transporter E3384_07895 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component E3384_07900 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component E3384_07905 ENOG4105E43 Extracellular solute-binding protein, family 5 E3384_07910 ENOG4105CXC rtn protein E3384_07915 ENOG4107TT5 NLP P60 protein E3384_07920 ENOG41076MN Phosphoesterase, PA-phosphatase related E3384_07925 ENOG4105CKI cobalamin synthesis protein E3384_07930 ENOG4105FUQ Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) E3384_07935 ENOG4105KRS Proteinase inhibitor E3384_07950 ENOG4105S8Q sugar efflux transporter E3384_07955 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein E3384_07960 ENOG4105DE4 1-phosphofructokinase E3384_07965 ENOG4105DM4 PTS System E3384_07975 ENOG4105HMI Membrane E3384_07980 ENOG4105DUM transcriptional regulator, lysR family E3384_07985 ENOG4108IQI permease E3384_07990 ENOG4105D05 Receptor E3384_07995 ENOG4105CXY transporter E3384_08000 ENOG4105EAC phosphoserine phosphatase E3384_08005 ENOG4105EJQ L-serine dehydratase E3384_08025 ENOG4105DHF Membrane E3384_08030 ENOG41060NJ transcriptional regulator E3384_08035 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator E3384_08040 ENOG4105C2J ABC transporter E3384_08045 ENOG4107SDZ Galactoside transport system permease protein mglC E3384_08050 ENOG4107SJI Dehydrogenase E3384_08055 ENOG4105BZ8 glutamate synthase E3384_08060 ENOG4105Y9N Membrane E3384_08065 ENOG4107GZ4 SanA protein E3384_08075 ENOG41067MG lrgb family E3384_08105 ENOG4108RXX maleylacetoacetate isomerase E3384_08110 ENOG4105MSY salicylate hydroxylase E3384_08115 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) E3384_08125 ENOG4105ETP RND efflux system, outer membrane lipoprotein E3384_08130 ENOG4105H9W Short-chain dehydrogenase reductase Sdr E3384_08135 ENOG4105KHU inner membrane protein YohD E3384_08140 ENOG41069YE inner membrane protein yohC E3384_08145 ENOG41061WM D-Alanyl-D-Alanine E3384_08150 ENOG4105CXG d-lactate dehydrogenase E3384_08155 ENOG4107QK4 glycoside hydrolase, family 3 domain protein E3384_08160 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system E3384_08165 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component E3384_08170 ENOG4108IJ8 ABC transporter E3384_08175 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component E3384_08190 ENOG4108HRK Histidine kinase E3384_08195 ENOG4108NEV two component transcriptional regulator, LytTR family E3384_08200 ENOG4108W15 Protein of unknown function (DUF1456) E3384_08210 ENOG4108YCW (LipO)protein E3384_08220 ENOG4105D1F ATP-binding protein E3384_08235 ENOG4108MQF Chaperone E3384_08240 ENOG4105CW0 outer membrane usher protein E3384_08245 ENOG410662B Type-1 fimbrial protein E3384_08250 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly E3384_08260 ENOG4105DWF phosphomethylpyrimidine kinase E3384_08265 ENOG4105FDP GntR family transcriptional regulator E3384_08270 ENOG4108TFM Kinase, PfkB family E3384_08275 ENOG4108KD5 ADP-ribosylation crystallin J1 E3384_08280 ENOG4105EAA nucleoside E3384_08285 ENOG4105EIE fructose-bisphosphate aldolase E3384_08300 ENOG41090V3 Tir chaperone protein (CesT) family E3384_08310 ENOG4105CFP Peptidase U32 E3384_08330 ENOG4105E3W Two component transcriptional regulator (Winged helix family E3384_08335 ENOG4105EB3 Histidine kinase E3384_08365 ENOG4105R8A Heat shock protein E3384_08370 ENOG4105D03 DNA-3-methyladenine glycosylase II E3384_08375 ENOG4105BZU Histidine kinase E3384_08390 ENOG4108GAE asmA family E3384_08395 ENOG4105EE5 Membrane protein terC E3384_08400 ENOG4105DAY polysaccharide export protein E3384_08405 ENOG4105KJF protein tyrosine phosphatase E3384_08410 ENOG4105D75 Capsular exopolysaccharide family E3384_08415 ENOG41090RK glycosyl transferase E3384_08420 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB E3384_08425 ENOG4107RXY Glycosyl transferase E3384_08430 ENOG4108NYJ Colanic acid E3384_08435 ENOG4105ECJ Glycosyl Transferase E3384_08440 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF E3384_08445 ENOG4105C0K Gdp-mannose 4,6-dehydratase E3384_08450 ENOG4105C30 Nad-dependent epimerase dehydratase E3384_08455 ENOG4105FGF GDP-mannose mannosyl hydrolase E3384_08460 ENOG4106CD9 glycosyl transferase group 1 E3384_08465 ENOG4105CJT Mannose-1-phosphate guanylyltransferase E3384_08470 ENOG4107QKV phosphomannomutase E3384_08475 ENOG4105D3Q Sugar transferase E3384_08480 ENOG4105PSV Polysaccharide Biosynthesis Protein E3384_08485 ENOG4105C74 pyruvyl transferase E3384_08490 ENOG4107T8Q Glycosyl transferase (Group 1 E3384_08495 ENOG4105G1A colanic acid biosynthesis protein E3384_08500 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase E3384_08515 ENOG4108NMT An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity) E3384_08540 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) E3384_08545 ENOG4105C6Y Udp-glucose 6-dehydrogenase E3384_08550 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) E3384_08555 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase E3384_08600 ENOG4108535 NAD dependent epimerase/dehydratase family E3384_08605 ENOG4105EQ1 Transcriptional regulator E3384_08615 ENOG4105CUB amino acid E3384_08620 ENOG4105CJB Exodeoxyribonuclease I E3384_08635 ENOG4108J2R molybdopterin oxidoreductase E3384_08640 ENOG4105QAX Iron-sulfur E3384_08645 ENOG4108NWD Cytochrome E3384_08650 ENOG4105DZ1 carboxypeptidase E3384_08655 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) E3384_08660 ENOG4105DR8 Membrane E3384_08670 ENOG4105JZC GHMP kinase E3384_08675 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) E3384_08680 ENOG4105KTW ethanolamine utilization protein E3384_08685 ENOG4105M3W utilization protein E3384_08695 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) E3384_08700 ENOG4108EKI Dehydrogenase E3384_08705 ENOG4108EKI Dehydrogenase E3384_08715 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml E3384_08725 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) E3384_08730 ENOG4105S3V Carbon dioxide concentrating mechanism protein E3384_08735 ENOG4105KNY Microcompartments protein E3384_08745 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit E3384_08750 ENOG4108ZFT Dehydratase small subunit E3384_08755 ENOG4105YCI dehydratase medium subunit E3384_08760 ENOG4105DMB glycerol dehydratase E3384_08765 ENOG4105EHR propanediol utilization protein pduB E3384_08770 ENOG4105KNY Microcompartments protein E3384_08775 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) E3384_08780 ENOG4107XVH Transcriptional regulator E3384_08785 ENOG4105C0Y Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) E3384_08790 ENOG4105DH2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity) E3384_08795 ENOG41081F0 Precorrin-8x methylmutase E3384_08805 ENOG4108DR9 Cobalt-precorrin-6Y C(5)-methyltransferase E3384_08810 ENOG4107XSI cobalt-precorrin-6y C15-methyltransferase E3384_08815 ENOG4105CIA precorrin-4 C(11)-methyltransferase E3384_08820 ENOG4108P62 biosynthesis protein (CbiG) E3384_08825 ENOG4105E4R Precorrin-3B C17-methyltransferase E3384_08830 ENOG4105QUC reductase E3384_08835 ENOG4107PPM cobalt chelatase E3384_08840 ENOG4105DVK Precorrin-2 c20-methyltransferase E3384_08845 ENOG4105CFT Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) E3384_08855 ENOG4108V4M Cobalt abc transporter E3384_08860 ENOG4108JJB ABC transporter E3384_08870 ENOG4108YZT Adenosylcobinamide kinase E3384_08885 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein E3384_08895 ENOG4105UQX Mate efflux family protein E3384_08945 ENOG4105FYV Amp nucleosidase E3384_09020 ENOG4105KT5 UmuD protein E3384_09025 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) E3384_09040 ENOG4105FCK Membrane E3384_09045 ENOG4105Y0K Inner membrane protein YedR E3384_09050 ENOG4105EST Metal Dependent Phosphohydrolase E3384_09055 ENOG4105DVF Cytosine-specific methyltransferase E3384_09060 ENOG41090BB DNA mismatch endonuclease (vsr) E3384_09065 ENOG4105FDR Membrane E3384_09070 ENOG4105CKW Inner membrane protein yedI E3384_09075 ENOG4105VNZ cytoplasmic protein E3384_09090 ENOG4105YX3 cellular response to acidity E3384_09100 ENOG4107TKS colanic acid capsular biosynthesis activation protein A E3384_09105 ENOG4105D19 Role in flagellar biosynthesis (By similarity) E3384_09110 ENOG4105VS8 Flagellar biosynthetic protein fliq E3384_09115 ENOG4105CN7 Flagellar biosynthetic protein FliP E3384_09120 ENOG4105K0P flagellar biosynthesis protein E3384_09125 ENOG4105DD5 Flagellar motor switch protein E3384_09130 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) E3384_09135 ENOG4107ZI8 flagellar basal body-associated protein flil E3384_09140 ENOG4105WF4 Flagellar hook-length control protein E3384_09145 ENOG4105GSA Flagellar export protein flij E3384_09150 ENOG4108JIR Flagellum-specific ATP synthase E3384_09155 ENOG41090PJ Flagellar assembly protein E3384_09160 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) E3384_09165 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) E3384_09180 ENOG4105KSU Redox protein E3384_09185 ENOG41066VF YeeE YedE family protein E3384_09190 ENOG4105JCU Inherit from NOG: (Lipo)protein E3384_09195 ENOG4105E5K Alpha-amylase E3384_09205 ENOG4105MQ3 flagellar protein FliS E3384_09210 ENOG4105DTS flagellar hook-associated E3384_09215 ENOG4105I03 Flagellin E3384_09220 ENOG4108C80 FliB family E3384_09225 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) E3384_09230 ENOG4108M9K flagella biosynthesis protein FliZ E3384_09235 ENOG4105EAB amino acid AbC transporter E3384_09245 ENOG4105E5Q amino acid AbC transporter E3384_09250 ENOG4105CDA abc transporter atp-binding protein E3384_09255 ENOG4105VJY transcriptional regulator E3384_09260 ENOG4105XVG cytoplasmic protein E3384_09270 ENOG4105WH1 Two component transcriptional regulator luxr family E3384_09315 ENOG4106RHG Yeca family E3384_09320 ENOG4105E0U tyrosine-specific transport protein E3384_09325 ENOG4105VVZ metal-binding protein E3384_09330 ENOG41090A1 ferritin E3384_09335 ENOG4105P23 (LipO)protein E3384_09345 ENOG4108UEC Ferritin-like protein E3384_09360 ENOG4108K4C ec 3.1.3.12 E3384_09370 ENOG4108VA4 Universal stress protein E3384_09380 ENOG4105GEH Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity) E3384_09385 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region E3384_09390 ENOG4107RD7 Flagellar Motor Protein, MotA E3384_09395 ENOG4105ER2 Ompa motb domain protein E3384_09400 ENOG4105CBS Chea signal transduction histidine kinase E3384_09405 ENOG4108V3W Chemotaxis protein, CheW E3384_09410 ENOG4105C8Q Methyl-accepting chemotaxis E3384_09415 ENOG4105BZU Histidine kinase E3384_09425 ENOG4108VYJ response regulator receiver protein E3384_09430 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) E3384_09435 ENOG4105D00 flagellar biosynthetic protein flhB E3384_09440 ENOG4105D7B Flagellar biosynthesis protein flha E3384_09445 ENOG4105IRD Flagellar protein FlhE E3384_09450 ENOG4105F5H Glycosyl Hydrolase Family 88 E3384_09465 ENOG4106ZCM YecM protein E3384_09485 ENOG4105WJG Glutathione E3384_09490 ENOG41081XQ Conserved Protein E3384_09495 ENOG4105D3W isochorismatase E3384_09505 ENOG4108TIT dATP pyrophosphohydrolase E3384_09525 ENOG4107S01 Repressor protein MetJ E3384_09545 ENOG4105FAV ABC, transporter E3384_09555 ENOG4105NXV High-affinity zinc uptake system protein E3384_09560 ENOG4105DR5 peptidase E3384_09565 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase E3384_09570 ENOG4105CA9 Pyruvate kinase E3384_09580 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase E3384_09585 ENOG4105C01 Dihydroxy-acid dehydratase E3384_09590 ENOG4108UHU Aldolase E3384_09600 ENOG4105X2V dna damage-inducible protein E3384_09610 ENOG4108Q2J Inner membrane protein YebE E3384_09615 ENOG4105CUG Oligopeptidase b E3384_09620 ENOG4105UMD exodeoxyribonuclease X E3384_09625 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase E3384_09630 ENOG4105MPK DNA polymerase III subunit theta E3384_09635 ENOG4105FXM Copper resistance protein E3384_09640 ENOG4108PNC copper resistance E3384_09645 ENOG4105NKT exported protein E3384_09660 ENOG41076J9 exonuclease VIII E3384_09670 ENOG4108YV9 Protein of unknown function (DUF2514) E3384_09735 ENOG4105DWP Membrane E3384_09760 ENOG4105C22 threonyL-tRNA synthetase E3384_09780 ENOG41064WM Uncharacterized protein YcgX E3384_09785 ENOG4106EWC guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling E3384_09795 ENOG4108R1E Serine threonine protein phosphatase 1 E3384_09800 ENOG4105UVW uncharacterized protein yebW E3384_09805 ENOG4105WT8 Protein of unknown function (DUF1480) E3384_09815 ENOG4105DY2 Paraquat-inducible protein b E3384_09820 ENOG4105H2K paraquat-inducible protein a E3384_09825 ENOG4108ZGC gaf domain protein E3384_09835 ENOG4105CN1 protease E3384_09845 ENOG4105C0R drug resistance transporter emrb qaca subfamily E3384_09850 ENOG4105J4Q Transcriptional regulator E3384_09865 ENOG4105Q3Y exported protein E3384_09870 ENOG410610J Protein of unknown function (DUF2627) E3384_09875 ENOG4105VEQ Cold shock protein E3384_09880 ENOG4105CJN penicillin-binding protein E3384_09885 ENOG4105DHI Methyltransferase E3384_09900 ENOG4105F3R pts system mannose fructose sorbose family iid E3384_09905 ENOG4105ETZ PTS System E3384_09910 ENOG4108EQA pts system E3384_09915 ENOG4105EE5 Membrane protein terC E3384_09920 ENOG4107XTP (EAL) domain protein E3384_09925 ENOG4105EJQ L-serine dehydratase E3384_09935 ENOG4105CRQ synthase (Component I) E3384_09945 ENOG4105M4H endoribonuclease L-psp E3384_09950 ENOG4105DVT helicase E3384_09955 ENOG41072GX Peptidase M22 Glycoprotease E3384_09960 ENOG4105Y4Z Outer Membrane Lipoprotein E3384_09965 ENOG4105CEY Amp-dependent synthetase and ligase E3384_09970 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) E3384_09980 ENOG4107QMS site-determining protein E3384_09995 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase E3384_10010 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation E3384_10035 ENOG4105ED1 spovr family E3384_10045 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) E3384_10055 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A E3384_10065 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) E3384_10080 ENOG4105D82 Glutamate dehydrogenase E3384_10090 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii E3384_10095 ENOG4105C4M (Ubiquinol oxidase) subunit I E3384_10100 ENOG4105MVP hydrogenase-1 operon protein HyaF E3384_10105 ENOG4108VXY Hydrogenase-1 operon protein HyaE E3384_10110 ENOG4108USZ hydrogenase E3384_10115 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit E3384_10125 ENOG4105E3S small subunit E3384_10140 ENOG4105C3G gtp-binding protein E3384_10150 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria E3384_10155 ENOG4105CHH sulfate transporter E3384_10160 ENOG4105C5T Phosphoribosyl pyrophosphate synthase E3384_10185 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) E3384_10190 ENOG4108YY7 Invasion gene expression up-regulator SirB E3384_10195 ENOG41063JG Transcriptional regulator E3384_10205 ENOG4105EWV Sodium calcium exchanger membrane region E3384_10210 ENOG4105WS7 Cation transport regulator E3384_10215 ENOG41090EX DsrE family E3384_10220 ENOG4105ID0 Putative invasin E3384_10225 ENOG4105WH1 Two component transcriptional regulator luxr family E3384_10230 ENOG4105BZU Histidine kinase E3384_10235 ENOG4105DQQ Major facilitator superfamily MFS_1 E3384_10240 ENOG4105CRU nitrate reductase, alpha subunit E3384_10245 ENOG4108IUE nitrate reductase beta subunit E3384_10250 ENOG4105R3A Nitrate reductase E3384_10255 ENOG41076YT nitrate reductase, gamma subunit E3384_10300 ENOG4105CIY formyltetrahydrofolate deformylase E3384_10310 ENOG4105D78 K07001 NTE family protein E3384_10315 ENOG4105I93 response regulator E3384_10320 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase E3384_10335 ENOG4108EKI Dehydrogenase E3384_10340 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein E3384_10350 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component E3384_10355 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component E3384_10360 ENOG4105C3U ABC transporter E3384_10365 ENOG4108JQ7 (ABC) transporter E3384_10370 ENOG4105EYW Ion transport protein E3384_10390 ENOG4105K9H YciI-like protein E3384_10395 ENOG410822N TonB family E3384_10415 ENOG4105PI0 Ferredoxin E3384_10420 ENOG4105EIF outer membrane protein W E3384_10425 ENOG4105WEF catalase E3384_10435 ENOG4108Z9Z response to DNA damage stimulus E3384_10455 ENOG4105DK0 Indole-3-glycerol phosphate synthase E3384_10460 ENOG4108EFP Anthranilate synthase component II E3384_10465 ENOG4105CRQ synthase (Component I) E3384_10475 ENOG4105DB7 PHP domain protein E3384_10480 ENOG4107RTD sua5 ycio yrdc ywlc family protein E3384_10485 ENOG4105FE9 pseudouridine synthase E3384_10490 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase E3384_10495 ENOG4105UBK short-chain dehydrogenase reductase E3384_10500 ENOG4105ERU peptidase E3384_10505 ENOG4105RKX Protein of unknown function (DUF2498) E3384_10510 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) E3384_10520 ENOG4107R11 Transcriptional regulator E3384_10535 ENOG4107QM5 aconitate hydratase E3384_10545 ENOG4105EYK Phosphatidylglycerophosphatase B E3384_10550 ENOG4105Q4A inner membrane protein yciS E3384_10555 ENOG4105CFV Tetratricopeptide repeat protein E3384_10565 ENOG4108ZJT translation initiation factor, Sui1 E3384_10570 ENOG41061RM osmotically inducible lipoprotein E3384_10575 ENOG4105N2W Transcriptional regulator E3384_10585 ENOG4105BZU Histidine kinase E3384_10595 ENOG4105Q4T oxidoreductase E3384_10600 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH E3384_10625 ENOG4108JQ2 peptide transport system atp-binding protein E3384_10630 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein E3384_10635 ENOG4108EU3 peptide transport system, permease E3384_10640 ENOG4108I5W peptide transport system, permease protein E3384_10645 ENOG4108J59 Extracellular solute-binding protein, family 5 E3384_10650 ENOG4105E51 psp operon transcriptional activator E3384_10655 ENOG41087YS Phage shock protein A E3384_10660 ENOG4105YYT phage shock protein B E3384_10665 ENOG4105FM1 phage shock protein C E3384_10670 ENOG4105NNG Peripheral inner membrane phage-shock protein E3384_10675 ENOG4105K8Z Phage shock protein E3384_10680 ENOG4105CM6 amino acid regulated cytosolic protein E3384_10690 ENOG4108JU8 Transcriptional regulator E3384_10695 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) E3384_10700 ENOG4107S8C mandelate racemase muconate lactonizing E3384_10705 ENOG4105KXI murein peptide amidase A E3384_10710 ENOG4107QSI ABC, transporter E3384_10720 ENOG4105HEI LysR family (Transcriptional regulator E3384_10725 ENOG4105CV8 reductase E3384_10730 ENOG4105F6U Short-chain dehydrogenase reductase Sdr E3384_10735 ENOG4108XFH Transcriptional regulator E3384_10750 ENOG4106PHM regulatory protein E3384_10770 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) E3384_10790 ENOG4105D64 Mechanosensitive ion channel E3384_10795 ENOG4105S5I Membrane E3384_10800 ENOG4105Q9Y Universal stress protein E3384_10810 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) E3384_10815 ENOG4108DG9 Smr protein MutS2 E3384_10820 ENOG4105C8Q Methyl-accepting chemotaxis E3384_10835 ENOG4105C1J atp-dependent rna helicase E3384_10850 ENOG410814C multidrug resistance protein E3384_10855 ENOG4108RW8 Universal stress protein F E3384_10860 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) E3384_10875 ENOG41090X5 Heat shock protein hslJ E3384_10880 ENOG4105C5I Dehydrogenase E3384_10885 ENOG4107H52 Dicarboxylate transport E3384_10890 ENOG410689M (LipO)protein E3384_10895 ENOG4105WXT Conserved Protein E3384_10910 ENOG4105CQ7 ATP-dependent helicase E3384_10915 ENOG4107DB1 DUF218 domain E3384_10920 ENOG4105CPW cytochrome b561 E3384_10925 ENOG4108WF3 methyltransferase E3384_10935 ENOG4105E5Q amino acid AbC transporter E3384_10945 ENOG4105E5Q amino acid AbC transporter E3384_10950 ENOG4107R0W ABC transporter E3384_10960 ENOG4107ZUJ lipid metabolic process E3384_10985 ENOG4105C8Q Methyl-accepting chemotaxis E3384_10990 ENOG4105DDW LysR family Transcriptional regulator E3384_10995 ENOG4105E32 cytoplasmic protein E3384_11000 ENOG4105EBR Carboxylesterase E3384_11005 ENOG4105DJ9 glucan biosynthesis protein E3384_11010 ENOG4108YYC ycei family E3384_11025 ENOG4108PQ7 sgc region transcriptional regulator E3384_11030 ENOG4108RK0 3-epimerase E3384_11035 ENOG4108XBJ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) E3384_11040 ENOG4106P19 photosystem i assembly btpa E3384_11045 ENOG4105DT3 PTS system, galactitol-specific IIc component E3384_11050 ENOG4105K18 The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) E3384_11055 ENOG4105CN9 Peptidase m42 family protein E3384_11060 ENOG4108Z9I -acetyltransferase E3384_11065 ENOG4107WE3 acetyltransferase YdcK E3384_11070 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein E3384_11075 ENOG41088CC tellurite resistance protein tehB E3384_11080 ENOG4108KKZ (LipO)protein E3384_11085 ENOG4105DKK Benzoate E3384_11090 ENOG4108JCI Transcriptional regulator E3384_11095 ENOG4105CFP Peptidase U32 E3384_11100 ENOG4105RR0 Protein of unknown function (DUF2554) E3384_11120 ENOG4108UQS dipeptidase E3384_11125 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family E3384_11140 ENOG410654E Membrane E3384_11160 ENOG4105R71 cytoplasmic protein E3384_11165 ENOG4108T9Y Inner membrane protein ydcZ E3384_11170 ENOG4108Z7F N-acetyltransferase E3384_11175 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein E3384_11180 ENOG4108WYP Transcriptional regulator E3384_11185 ENOG4105CHB tonB-dependent Receptor E3384_11190 ENOG4108NS2 receptor E3384_11195 ENOG4105SUV lipoprotein YgdR E3384_11200 ENOG4105C85 amino acid E3384_11215 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase E3384_11220 ENOG4105JAB phenazine biosynthesis protein, phzf family E3384_11225 ENOG4105D0D Nitrate reductase 2, gamma subunit E3384_11230 ENOG4108NZN Respiratory nitrate reductase 2 delta chain E3384_11235 ENOG4108IUE nitrate reductase beta subunit E3384_11240 ENOG4105CRU nitrate reductase, alpha subunit E3384_11245 ENOG4107QND Nitrite extrusion protein E3384_11280 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein E3384_11285 ENOG4108MG3 formate dehydrogenase E3384_11290 ENOG4105DQ4 alcohol dehydrogenase E3384_11305 ENOG4105TPS biofilm-dependent modulation protein E3384_11310 ENOG4108Z9K Osmotically inducible protein E3384_11315 ENOG4105XXV Acid-resistance protein E3384_11325 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) E3384_11340 ENOG4105C87 Aminotransferase class I and II E3384_11345 ENOG4105DFD Na H antiporter E3384_11350 ENOG41060NJ transcriptional regulator E3384_11395 ENOG4108UQ8 endoribonuclease L-psp E3384_11400 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) E3384_11410 ENOG4107SCK Monooxygenase E3384_11425 ENOG4108I5G Major Facilitator superfamily E3384_11430 ENOG4105CPQ Dehydrogenase E3384_11435 ENOG4105C6F GntR Family Transcriptional Regulator E3384_11450 ENOG4105DPX Hydrogenase, large subunit E3384_11455 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit E3384_11475 ENOG4105MVP hydrogenase-1 operon protein HyaF E3384_11500 ENOG4105FFC UPF0187 protein E3384_11505 ENOG4105M0C cytoplasmic protein E3384_11515 ENOG4105C26 Dehydrogenase E3384_11520 ENOG4105EGI Transcriptional regulator E3384_11535 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes E3384_11545 ENOG4106DNR multiple antibiotic resistance protein E3384_11550 ENOG4108594 Permease of the drug metabolite transporter E3384_11555 ENOG4105E5W Transporter E3384_11565 ENOG4108YDI single-species biofilm formation on inanimate substrate E3384_11570 ENOG4108WTK competence damage-inducible protein E3384_11585 ENOG4105DGW oligopeptidase A E3384_11590 ENOG4105EMU Dehydrogenase E3384_11595 ENOG4107XBN GntR Family Transcriptional Regulator E3384_11600 ENOG41061EV selenium-binding protein YdfZ E3384_11605 ENOG4105DEI Mannitol dehydrogenase E3384_11615 ENOG4105CPQ Dehydrogenase E3384_11635 ENOG4108MK9 spermidine N(1)-acetyltransferase E3384_11645 ENOG4105KBG Protein of unknown function (DUF1161) E3384_11650 ENOG4107QY8 reductase E3384_11655 ENOG4105C3J Cysteine desulfurase E3384_11660 ENOG4105QAX Iron-sulfur E3384_11665 ENOG4107KGK dmso reductase anchor subunit E3384_11670 ENOG4108NEM leader-binding protein dmsD E3384_11675 ENOG4108U0I binding-protein-dependent transport systems inner membrane Component E3384_11680 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system E3384_11685 ENOG4105E90 ABC transporter E3384_11690 ENOG4108IJ8 ABC transporter E3384_11700 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) E3384_11705 ENOG4105DAG ROK family E3384_11710 ENOG4106NZI LysR family Transcriptional regulator E3384_11715 ENOG4105D94 Major Facilitator Superfamily E3384_11725 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap E3384_11745 ENOG4105DSF transport protein E3384_11750 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) E3384_11755 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) E3384_11760 ENOG4105C5D exported protein E3384_11765 ENOG4105D5Q Arginine ornithine antiporter E3384_11770 ENOG4105RA2 Membrane E3384_11775 ENOG4107EXC regulatoR E3384_11785 ENOG4105FCK Membrane E3384_11790 ENOG4105CPN adenine deaminase E3384_11795 ENOG4105JJR Histidine kinase E3384_11805 ENOG4105C9Q fumarate hydratase class II E3384_11810 ENOG4107GFK fumarate E3384_11815 ENOG4105EIP mannose-6-phosphate isomerase E3384_11820 ENOG4106J39 exported protein E3384_11830 ENOG4105C87 Aminotransferase class I and II E3384_11840 ENOG4105D9R oxidoreductase E3384_11845 ENOG4106C6R beta-lactam resistance protein E3384_11855 ENOG4105M9B inner membrane protein ydgK E3384_11880 ENOG4108UQQ Electron transport complex E3384_11890 ENOG4105CSM endonuclease III E3384_11895 ENOG4105DUX Transporter E3384_11900 ENOG4108K3A Glutathione S-transferase E3384_11920 ENOG410642K Lysozyme inhibitor E3384_11930 ENOG4108XTF Outer Membrane Lipoprotein E3384_11945 ENOG4105Y49 secretion protein, HlyD family E3384_11950 ENOG4105DSW Fusaric acid resistance protein E3384_11955 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) E3384_11960 ENOG4107RGM aldo keto reductase E3384_11965 ENOG4105XZD Fe-S protein E3384_11970 ENOG4108WUH Transcriptional regulator, TetR family E3384_11975 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase E3384_11980 ENOG4108UYE Lactoylglutathione lyase E3384_11995 ENOG4105M2J Glutaredoxin E3384_12000 ENOG4105K4H Nlp p60 protein E3384_12005 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) E3384_12020 ENOG4105F52 Transcriptional regulator E3384_12025 ENOG4105CZQ inner membrane transport protein YdhC E3384_12030 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase E3384_12035 ENOG4108R6K riboflavin synthase, subunit alpha E3384_12055 ENOG4108IUF type iii secretion E3384_12060 ENOG4108TN6 type iii secretion E3384_12065 ENOG41083GP type iii secretion E3384_12070 ENOG4108HHI Type III secretion system protein E3384_12075 ENOG41063Q7 Type III secretion system protein E3384_12090 ENOG4108JIR Flagellum-specific ATP synthase E3384_12100 ENOG4106H1D secretion system apparatus protein E3384_12105 ENOG4105UQF type iii secretion E3384_12110 ENOG4106563 type III secretion system apparatus protein E3384_12160 ENOG4106FZW pathogenicity island effector protein E3384_12165 ENOG4108SZ7 secretion system effector E3384_12175 ENOG4105ZQI secreted protein E3384_12205 ENOG4105BZU Histidine kinase E3384_12215 ENOG4108XDN Transcriptional regulator E3384_12220 ENOG4107SEY Conserved Protein E3384_12225 ENOG4105RFR Protein of unknown function (DUF2767) E3384_12230 ENOG4108ZXC Two component transcriptional regulator, luxr family E3384_12235 ENOG4106AFQ Histidine kinase E3384_12240 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein E3384_12245 ENOG4106WHD Tetrathionate reductase E3384_12250 ENOG4105DB1 molybdopterin oxidoreductase E3384_12255 ENOG4108RVA ribokinase E3384_12265 ENOG4107RCM Releases the N-terminal proline from various substrates (By similarity) E3384_12270 ENOG4105CUB amino acid E3384_12275 ENOG4105CA9 Pyruvate kinase E3384_12295 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein E3384_12310 ENOG4105JRK feS assembly protein SufD E3384_12315 ENOG4105C3K feS assembly ATPase SufC E3384_12320 ENOG4105DIW FeS assembly protein SUFB E3384_12325 ENOG4108Z4V iron-sulfur cluster assembly E3384_12330 ENOG4108ETY sodium dicarboxylate symporter E3384_12335 ENOG410671Z uncharacterized protein ydiH E3384_12340 ENOG4105KA0 thioesterase Superfamily protein E3384_12345 ENOG4105CQB FAD linked oxidase domain protein E3384_12350 ENOG4105IPI Membrane E3384_12360 ENOG4105SUA Ydil protein E3384_12365 ENOG4105EMV Major Facilitator E3384_12370 ENOG4105EMV Major Facilitator E3384_12385 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) E3384_12390 ENOG4105C1G acyl-Coa dehydrogenase E3384_12395 ENOG4105W4W Transcriptional regulator E3384_12400 ENOG4105CV7 Electron transfer flavoprotein E3384_12405 ENOG4105C10 Electron transfer flavoprotein E3384_12410 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase E3384_12415 ENOG41090P5 ferredoxin-like protein E3384_12420 ENOG4105CEY Amp-dependent synthetase and ligase E3384_12425 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) E3384_12435 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) E3384_12440 ENOG4106EDX Hemin uptake protein E3384_12455 ENOG4108QBX (LipO)protein E3384_12465 ENOG4108V06 Glutathione peroxidase E3384_12475 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) E3384_12480 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) E3384_12495 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) E3384_12500 ENOG41082NX 50s ribosomal protein l35 E3384_12505 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) E3384_12530 ENOG4108NE3 Salt-induced outer membrane protein E3384_12535 ENOG4105DE4 1-phosphofructokinase E3384_12540 ENOG4105P10 Uncharacterized protein ydiZ E3384_12545 ENOG4105FGM Fructosamine kinase E3384_12550 ENOG4107PN8 YfeABCD locus regulator E3384_12555 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 E3384_12560 ENOG4107K5X Membrane-bound metal-dependent hydrolase E3384_12565 ENOG4108ETY sodium dicarboxylate symporter E3384_12575 ENOG4105CH6 catalase E3384_12585 ENOG4105F8D glycoside hydrolase family 4 E3384_12590 ENOG4105EZV Transcriptional regulator E3384_12595 ENOG4105VCP PTS System E3384_12600 ENOG4105CK1 PTS System E3384_12605 ENOG4105VZJ PTS System E3384_12615 ENOG4105KKI DNA-binding transcriptional activator OsmE E3384_12625 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) E3384_12630 ENOG4108SPG Periplasmic Protein E3384_12660 ENOG4105CGK Exodeoxyribonuclease III E3384_12665 ENOG4105M6F mutator MutT protein E3384_12670 ENOG4105MTM Protein of unknown function (DUF1496) E3384_12675 ENOG4105D82 Glutamate dehydrogenase E3384_12680 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) E3384_12685 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) E3384_12690 ENOG41069NU Nitroreductase E3384_12695 ENOG4105D07 Signal peptide peptidase, SppA E3384_12700 ENOG4105HDK L-asparaginase E3384_12705 ENOG4108RWI nicotinamidase E3384_12710 ENOG4108KUU Inner membrane metabolite transport protein ydjE E3384_12715 ENOG4105E98 transcriptional regulator DeoR family E3384_12720 ENOG4105CPC Aldo Keto reductase E3384_12725 ENOG4107UH8 sugar kinase E3384_12730 ENOG4105D2N Aldolase E3384_12735 ENOG4105CPQ Dehydrogenase E3384_12740 ENOG4107TE1 transport protein E3384_12745 ENOG4105CPQ Dehydrogenase E3384_12750 ENOG4105VUT cytoplasmic protein E3384_12760 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase E3384_12765 ENOG4105DSB aldose 1-epimerase E3384_12770 ENOG4105CV8 reductase E3384_12775 ENOG4105C4X radical SAM domain protein E3384_12780 ENOG4105GNX MltA-interacting MipA family protein E3384_12785 ENOG4105CYN Serine protein kinase E3384_12800 ENOG4108KHP Diguanylate cyclase E3384_12805 ENOG4108KXH Ybak prolyl-tRNA synthetase associated E3384_12820 ENOG4105R1U AraC Family Transcriptional Regulator E3384_12825 ENOG4105DJ2 Major Facilitator Superfamily E3384_12830 ENOG4105K78 MarR family Transcriptional regulator E3384_12840 ENOG4105UCG Domain of unknown function (DUF333) E3384_12845 ENOG4106G4W E3384_12850 ENOG4105Y3U Transglycosylase-associated protein E3384_12865 ENOG4105YP6 Domain of unknown function (DUF1869) E3384_12870 ENOG4108YS1 cytoplasmic protein E3384_12880 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) E3384_12895 ENOG4108Z6Z Transcriptional regulator E3384_12910 ENOG4108MEK Metal-binding protein YodA E3384_12925 ENOG4105D64 Mechanosensitive ion channel E3384_12930 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) E3384_12935 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) E3384_12945 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component E3384_12960 ENOG4108VKM cytochrome b561 E3384_12975 ENOG4108ZNX Heat shock protein E3384_13000 ENOG4105H38 Membrane E3384_13015 ENOG41060EU Cold shock-like protein E3384_13020 ENOG4106F2Y RICIN E3384_13025 ENOG4105Y50 Virulence Protein E3384_13045 ENOG4108HMX isocitrate dehydrogenase (NADP) E3384_13050 ENOG4108R99 pseudouridine synthase E3384_13075 ENOG4107QTF adenylosuccinate lyase E3384_13090 ENOG4105EZE Cupin 4 family protein E3384_13110 ENOG4105F38 ABC transporter, permease E3384_13120 ENOG4105D38 putrescine abc transporter E3384_13125 ENOG4107RUE extracellular solute-binding protein family 1 E3384_13130 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) E3384_13140 ENOG4105D60 lipoprotein releasing system transmembrane protein E3384_13150 ENOG4105D60 lipoprotein releasing system transmembrane protein E3384_13155 ENOG4108JA2 transcriptioN-repair coupling factor E3384_13160 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein E3384_13165 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction E3384_13170 ENOG4108IND Tetr family transcriptional regulator E3384_13175 ENOG4107MBR 17 kDa surface antigen E3384_13180 ENOG4105CEP NADH dehydrogenase E3384_13195 ENOG4108RUM thiamine kinase E3384_13200 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) E3384_13205 ENOG41090DQ Lipoprotein E3384_13210 ENOG4105K59 histidine triad (HIT) protein E3384_13215 ENOG4105CNM Receptor E3384_13220 ENOG4105CI1 PTS System E3384_13225 ENOG4105F8V Hydrolase, tatD family E3384_13230 ENOG4107QRG dna polymerase iii E3384_13240 ENOG4105HHA aminodeoxychorismate lyase E3384_13245 ENOG4105YAZ 4-amino-4-deoxychorismate lyase E3384_13250 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) E3384_13255 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) E3384_13260 ENOG4105CHR reductase E3384_13265 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase E3384_13285 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein E3384_13290 ENOG4108UHJ MAF-like protein E3384_13305 ENOG4105EI2 Pseudouridine synthase E3384_13310 ENOG41071G1 Uncharacterized protein YceQ E3384_13315 ENOG4107QQB Ribonuclease E E3384_13320 ENOG4105DTJ flagellar hook-associated protein E3384_13325 ENOG4105E1Q flagellar hook-associated protein E3384_13330 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj E3384_13345 ENOG4105CGA flagellar basal-body rod protein FlgG E3384_13350 ENOG4108KPB Flagellar basal-body rod protein FlgF E3384_13355 ENOG4105BZE flagellar hook protein, FlgE E3384_13360 ENOG4105W00 Flagellar hook capping protein E3384_13365 ENOG4108ZC9 flagellar basal-body rod protein flgc E3384_13370 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) E3384_13375 ENOG4105CKS Flagella basal body P-ring formation protein flgA E3384_13380 ENOG4105M9M anti-sigma28 factor FlgM E3384_13385 ENOG4105QVD Flagella synthesis protein FlgN E3384_13390 ENOG4105CJR Integral membrane protein (MviN E3384_13395 ENOG4105EP9 oxidoreductase E3384_13405 ENOG4105D9U N-acetyltransferase E3384_13415 ENOG4105E9S glutaredoxin 2 E3384_13420 ENOG4105F3T (LipO)protein E3384_13430 ENOG4105MEA DNA damage-inducible protein i E3384_13435 ENOG4105PVA Biofilm formation regulatory protein BssS E3384_13445 ENOG4106974 biofilm formation E3384_13450 ENOG4105DS1 cytochrome b561 E3384_13465 ENOG4105D1S lipid A biosynthesis E3384_13475 ENOG4108W47 Acidic protein msyB E3384_13480 ENOG4105NAC (LipO)protein E3384_13485 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) E3384_13500 ENOG4105EIK Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane (By similarity) E3384_13505 ENOG4107RZC phospholipase d E3384_13535 ENOG41086KC Transcriptional regulator E3384_13540 ENOG4108XDW curli assembly protein CsgE E3384_13545 ENOG4108WYR Curli production assembly transport component, CsgF E3384_13550 ENOG4105P8Q Curli production assembly transport component CsgG E3384_13555 ENOG4108UQ5 membrane protein YcdZ E3384_13560 ENOG4107XHZ cytoplasmic chaperone TorD family protein E3384_13585 ENOG4107RJ5 oxidoreductase E3384_13590 ENOG4105JHE Major Facilitator Superfamily E3384_13595 ENOG4108QGT oligogalacturonate-specific porin E3384_13605 ENOG4105C9S Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity) E3384_13610 ENOG4107RJ1 sodium solute E3384_13615 ENOG4105QEK Transcriptional regulator E3384_13620 ENOG4105D5M phosphate starvation-inducible protein E3384_13625 ENOG4105CK7 Sodium proline symporter E3384_13640 ENOG4108R86 Transcriptional regulator E3384_13645 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 E3384_13655 ENOG4105XH3 E3384_13660 ENOG4105D6F Phosphatase E3384_13665 ENOG4105N2G alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen E3384_13670 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) E3384_13675 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) E3384_13735 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase E3384_13740 ENOG4105C26 Dehydrogenase E3384_13750 ENOG4108V8F Transcriptional regulator, MarR family E3384_13755 ENOG4105EFA 4-hydroxyphenylacetate E3384_13760 ENOG4107UWN reductase E3384_13765 ENOG4105VT2 5-hydroxyisourate hydrolase E3384_13770 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E3384_13775 ENOG4107ZY3 Histidine kinase E3384_13790 ENOG4106YSC E3384_13795 ENOG4108N4M Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns 3-P and prevents the transition of PtdIns 3-P to PtdIns 3,5-P2. It is one of the known effectors injected by Salmonella into the host cell and is required for invasion and for an efficient generation and maintenance of Salmonella-containing vacuole (SVC). Alteration of the phosphoinositide composition of the plasma membrane causes membrane ruffling and actin cytoskeleton rearrangements. The persistence of PtdIns 3-P diverts the SCV from the endocytic pathway resulting in enlarged vesicles, which are essential to create a favorable environment where Salmonella can replicate and avoid immune defenses of the host cell E3384_13810 ENOG41084BJ Pentapeptide repeat protein E3384_13825 ENOG4108MN8 Membrane E3384_13835 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 E3384_13845 ENOG4108V1U phospholipid-binding protein E3384_13860 ENOG4105K4P CoA-binding domain protein E3384_13875 ENOG41088T4 Helicase IV E3384_13880 ENOG410901E Membrane E3384_13885 ENOG4105EM2 membrane E3384_13890 ENOG4108RZ1 DNA transformation protein E3384_13900 ENOG4105UYK outer membrane protein a E3384_13910 ENOG4105DAN ATP-dependent protease E3384_13920 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) E3384_13925 ENOG4108Q2G (LipO)protein E3384_13930 ENOG4105DY2 Paraquat-inducible protein b E3384_13935 ENOG4105F1S paraquat-inducible protein a E3384_13940 ENOG4105C5H ABC transporter E3384_13950 ENOG4105QVC MOSC domain-containing protein E3384_13955 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) E3384_13965 ENOG4105CD8 aminopeptidase N E3384_13970 ENOG4105Y50 Virulence Protein E3384_13990 ENOG4105UZW Tail fiber assembly protein E3384_13995 ENOG4108X9F tail fiber protein E3384_14060 ENOG4105D7V transposase E3384_14075 ENOG4105IM0 capsid protein E3384_14095 ENOG4107DE1 head-to-tail joining protein E3384_14100 ENOG4105UZW Tail fiber assembly protein E3384_14110 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium E3384_14115 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 E3384_14145 ENOG4105HGD Antitermination protein E3384_14185 ENOG4105JBR DNA replication protein E3384_14230 ENOG41076J9 exonuclease VIII E3384_14250 ENOG4107R08 Integrase E3384_14265 ENOG4107RCH Diaminopropionate ammonia-lyase E3384_14285 ENOG4105FCK Membrane E3384_14290 ENOG4105CGF Aromatic amino acid aminotransferase E3384_14295 ENOG4105C5X domain protein E3384_14300 ENOG4105EAQ (twin-arginine translocation) pathway signal E3384_14305 ENOG4105DIT ErfK YbiS YcfS YnhG family protein E3384_14320 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) E3384_14330 ENOG4106371 Methyltransferase E3384_14335 ENOG4107S90 membrAne E3384_14340 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups E3384_14360 ENOG4105T0Z Conserved Protein E3384_14375 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 E3384_14380 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) E3384_14385 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) E3384_14395 ENOG4108K0D peptidase, M48 E3384_14410 ENOG4107VMU Membrane E3384_14415 ENOG4105DDY UPF0142 protein ycaO E3384_14420 ENOG4105TMB Formate nitrite transporter E3384_14430 ENOG4105GUS E3384_14440 ENOG4105F1A Pyruvate formate-lyase E3384_14445 ENOG4105E5D amino acid E3384_14455 ENOG4107KGK dmso reductase anchor subunit E3384_14460 ENOG4105QAX Iron-sulfur E3384_14465 ENOG4107QY8 reductase E3384_14475 ENOG4105D1H recombination factor protein RarA E3384_14485 ENOG4105CNU cell division protein FtsK E3384_14490 ENOG4105EW9 transcriptional regulator AsnC family E3384_14495 ENOG4105C3M thioredoxin reductase E3384_14500 ENOG4108JJ9 ABC, transporter E3384_14505 ENOG4108JJ8 (ABC) transporter E3384_14520 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) E3384_14525 ENOG4105HEI LysR family (Transcriptional regulator E3384_14530 ENOG4105EUB pirin domain protein E3384_14535 ENOG4105CHJ isochorismatase hydrolase E3384_14550 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit E3384_14560 ENOG4105VEQ Cold shock protein E3384_14565 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) E3384_14570 ENOG4105DJY efflux transporter, rnd family, mfp subunit E3384_14575 ENOG4108MJ5 VirK protein E3384_14580 ENOG4105CPB ATP-dependent endonuclease of the OLD family E3384_14585 ENOG4105DWU Membrane E3384_14595 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) E3384_14600 ENOG4105C7K acetolactate synthase E3384_14605 ENOG4105C5W Aldolase E3384_14610 ENOG4105CGD Nad-dependent epimerase dehydratase E3384_14615 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase E3384_14620 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase E3384_14630 ENOG41064MM (LipO)protein E3384_14635 ENOG4105E5Z arginine transporter ATP-binding subunit E3384_14640 ENOG4106PMH Extracellular solute-binding protein family 3 E3384_14645 ENOG4105GBT ABC transporter E3384_14650 ENOG4105DMR ABC, transporter E3384_14655 ENOG4106TNF Periplasmic binding protein E3384_14675 ENOG4107SFS Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity) E3384_14680 ENOG4105RBQ inner membrane protein ybjO E3384_14685 ENOG4105D38 putrescine abc transporter E3384_14690 ENOG4105F38 ABC transporter, permease E3384_14695 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) E3384_14700 ENOG4107RUE extracellular solute-binding protein family 1 E3384_14705 ENOG4108RMJ sensory transduction regulator E3384_14715 ENOG4108DBC nitroreductase E3384_14720 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress E3384_14725 ENOG41090BQ Glutaredoxin E3384_14730 ENOG4105GWF inner membrane protein YbjM E3384_14745 ENOG4108RFG Tetr family transcriptional regulator E3384_14750 ENOG4106UW1 Major Facilitator superfamily E3384_14755 ENOG4108HCJ Hydrolase E3384_14760 ENOG4107QF7 multi-drug E3384_14765 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase E3384_14770 ENOG4107FB0 transcriptional regulator DeoR family E3384_14775 ENOG4105DZ1 carboxypeptidase E3384_14780 ENOG4108TGY Glutathione S-transferase E3384_14785 ENOG4105D8V Glucose sorbosone dehydrogenase E3384_14795 ENOG4105CY2 Citrate transporter E3384_14800 ENOG4108KB2 LysR family Transcriptional regulator E3384_14805 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase E3384_14815 ENOG4105C1G acyl-Coa dehydrogenase E3384_14825 ENOG4105C10 Electron transfer flavoprotein E3384_14830 ENOG4105BZJ Electron transfer flavoprotein E3384_14835 ENOG4105CI0 Citrate lyase E3384_14840 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway E3384_14855 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component E3384_14860 ENOG4105DEF Extracellular solute-binding protein, family 5 E3384_14865 ENOG4108JQ6 ABC transporter E3384_14870 ENOG4105D44 asparaginase E3384_14875 ENOG4105CVM Molybdenum cofactor synthesis domain protein E3384_14880 ENOG4105D06 uba thif-type nad fad binding protein E3384_14885 ENOG4105F1A Pyruvate formate-lyase E3384_14890 ENOG4105C6N Formate acetyltransferase E3384_14895 ENOG4108HCJ Hydrolase E3384_14900 ENOG41072TH Protein of unknown function (DUF1479) E3384_14905 ENOG4105C5H ABC transporter E3384_14910 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein E3384_14915 ENOG4105F4P )-transporter E3384_14920 ENOG4105KST dependent repressor E3384_14930 ENOG4108I6E Sulfatase E3384_14935 ENOG4108T1M outer membrane protein x E3384_14950 ENOG4107R0W ABC transporter E3384_14955 ENOG4105E5Q amino acid AbC transporter E3384_14960 ENOG4105CDA abc transporter atp-binding protein E3384_14965 ENOG4105D8X mechanosensitive ion channel E3384_14975 ENOG4105KSC Transcriptional regulator, TraR DksA family E3384_14980 ENOG4105VR4 UPF0379 protein ybiJ E3384_14985 ENOG4108MTB glycosyl transferase family E3384_14990 ENOG4105DVT helicase E3384_14995 ENOG4105C1J atp-dependent rna helicase E3384_15000 ENOG4107MVR Transcriptional regulator E3384_15010 ENOG4105CJ1 ABC, transporter E3384_15015 ENOG4107QWP ABC-2 type transporter E3384_15020 ENOG4107QWP ABC-2 type transporter E3384_15025 ENOG4105I9U inner membrane protein ybhQ E3384_15030 ENOG4105X23 Endonuclease Exonuclease phosphatase E3384_15035 ENOG4105DZQ phospholipase D Transphosphatidylase E3384_15040 ENOG4107UXM Membrane E3384_15060 ENOG4105HFZ Membrane E3384_15065 ENOG4108ZAF Molybdopterin E3384_15070 ENOG4105M00 molybdopterin converting factor, subunit 1 E3384_15080 ENOG4108RIR Molybdenum cofactor biosynthesis protein E3384_15090 ENOG4105CHW UPF0052 protein E3384_15115 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) E3384_15120 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) E3384_15135 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) E3384_15140 ENOG4108V1U phospholipid-binding protein E3384_15170 ENOG4105NBR Pectinesterase E3384_15180 ENOG4108K4B hydrolase E3384_15190 ENOG4105E0C molybdate abc transporter E3384_15195 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein E3384_15200 ENOG410680R Protein of unknown function (DUF2592) E3384_15205 ENOG4105F4R Transcriptional regulator mode E3384_15210 ENOG4105DKW ABC transporter E3384_15220 ENOG4105CMR udp-glucose 4-epimerase E3384_15225 ENOG4105F0Z galactose-1-phosphate uridylyltransferase E3384_15235 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) E3384_15245 ENOG4105E0A ABC, transporter E3384_15250 ENOG4105EHG Permease protein E3384_15255 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase E3384_15265 ENOG4107QSA Oxaloacetate decarboxylase E3384_15275 ENOG4107QWE )-transporter E3384_15285 ENOG4105C5Q Transcriptional regulator E3384_15290 ENOG4106DSS Tartrate dehydratase subunit alpha E3384_15295 ENOG4107GFK fumarate E3384_15300 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) E3384_15305 ENOG4105JND homeobox protein E3384_15310 ENOG4105PGM cation diffusion facilitator family transporter E3384_15315 ENOG4106Z1T Nicotinamide Mononucleotide Transporter E3384_15350 ENOG4105UFD tol-pal system protein YbgF E3384_15355 ENOG4105KCK Peptidoglycan-associated lipoprotein E3384_15365 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA E3384_15370 ENOG4105M8F Biopolymer transport protein exbD tolR E3384_15375 ENOG4105E02 MotA TolQ exbB proton channel E3384_15380 ENOG4107YD3 Thioesterase E3384_15385 ENOG4105KJB cyd operon protein YbgE E3384_15395 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii E3384_15400 ENOG4105C4M (Ubiquinol oxidase) subunit I E3384_15405 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha E3384_15415 ENOG4105C7S Dehydrogenase E3384_15420 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 E3384_15425 ENOG4105E33 succinate dehydrogenase E3384_15430 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) E3384_15435 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein E3384_15440 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit E3384_15445 ENOG4105BZN citrate synthase E3384_15450 ENOG4108KK1 membrane protein AbrB duplication E3384_15465 ENOG4107R7A Allophanate hydrolase subunit 2 E3384_15470 ENOG4105P4J Allophanate hydrolase, subunit 1 E3384_15475 ENOG4107QNR UPF0135 protein E3384_15485 ENOG4105CVP deoxyribo-dipyrimidine photolyase E3384_15490 ENOG4105XIQ Protein of unknown function (DUF2517) E3384_15500 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) E3384_15510 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) E3384_15515 ENOG4105C08 Histidine kinase E3384_15520 ENOG4105EEX Two component transcriptional regulator (Winged helix family E3384_15530 ENOG4105CXN decarboxylase E3384_15535 ENOG4105D5Q Arginine ornithine antiporter E3384_15545 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 E3384_15550 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) E3384_15555 ENOG4105EV9 Alpha Beta Hydrolase E3384_15560 ENOG4105NNH LexA regulated protein E3384_15565 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) E3384_15570 ENOG41090R7 Ferric uptake E3384_15575 ENOG4106P55 Transcriptional regulator E3384_15580 ENOG4107EFR Flavocytochrome c E3384_15585 ENOG41079YP Citrate utilization protein b E3384_15590 ENOG4105CSH Transporter E3384_15595 ENOG4105GX6 (LipO)protein E3384_15600 ENOG4105J5J Outer membrane porin E3384_15610 ENOG4105CI1 PTS System E3384_15620 ENOG4105CE4 GlcNAc 6-P deacetylase E3384_15625 ENOG4105E2R ROK family E3384_15630 ENOG4105D4U had-superfamily hydrolase, subfamily iia E3384_15635 ENOG4105CAQ asparagine synthetase E3384_15675 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family E3384_15685 ENOG4105C9A Phoh family E3384_15695 ENOG4108JU5 Magnesium and cobalt efflux protein E3384_15700 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) E3384_15705 ENOG4107RP9 extracellular solute-binding protein, family 3 E3384_15710 ENOG4105EAD ABC transporter E3384_15715 ENOG4105DRP amino acid AbC transporter E3384_15720 ENOG4105CDA abc transporter atp-binding protein E3384_15735 ENOG4105F7F Chaperone E3384_15740 ENOG4105QFC Hsc56 co-chaperone of HscC E3384_15745 ENOG41069CF Protein of unknown function (DUF1266) E3384_15750 ENOG4105QFC Hsc56 co-chaperone of HscC E3384_15755 ENOG41069CF Protein of unknown function (DUF1266) E3384_15765 ENOG4107PAI alpha helical protein E3384_15770 ENOG4108JUB Transcriptional regulator E3384_15775 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) E3384_15800 ENOG4105DJF DNA polymerase III, delta' subunit E3384_15805 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) E3384_15810 ENOG4107QZB decarboxylase E3384_15815 ENOG4108TGR phosphatase E3384_15820 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) E3384_15830 ENOG4105CJN penicillin-binding protein E3384_15835 ENOG4105CNI cell division protein FtsW E3384_15840 ENOG4105K6T rare lipoprotein A E3384_15845 ENOG4105DZ1 carboxypeptidase E3384_15850 ENOG4108Z43 UPF0250 protein E3384_15860 ENOG41064T2 transcriptional regulator, lysR family E3384_15875 ENOG4107QPI nitrilase cyanide hydratase and apolipoprotein n-acyltransferase E3384_15885 ENOG4105VEQ Cold shock protein E3384_15895 ENOG4105CEE C4-dicarboxylate transporter E3384_15900 ENOG4106YYS transcriptional regulatory protein E3384_15905 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism E3384_15910 ENOG4105DUA (citrate (pro-3S)-lyase ligase E3384_15915 ENOG4105XGS Covalent carrier of the coenzyme of citrate lyase (By similarity) E3384_15920 ENOG4105CI0 Citrate lyase E3384_15925 ENOG4105CHY citrate lyase, alpha E3384_15930 ENOG4105YGP holo-ACP synthase CitX E3384_15940 ENOG4107QPK )-transporter E3384_15945 ENOG4105KTS ribonuclease E3384_15950 ENOG4105NXH GreA GreB family elongation factor E3384_15955 ENOG4105E2A Dehydrogenase E3384_15960 ENOG4108U51 Universal stress protein E3384_15970 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein E3384_15975 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) E3384_15985 ENOG4108JU3 Alkyl hydroperoxide reductase E3384_15990 ENOG4105D3R alkyl hydroperoxide reductase E3384_15995 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase E3384_16005 ENOG4105BZV Phosphoadenosine phosphosulfate reductase E3384_16010 ENOG4105GTN ParB Domain Protein Nuclease E3384_16015 ENOG4105CHM Aminotransferase E3384_16020 ENOG4107SCQ Iron-containing alcohol dehydrogenase E3384_16025 ENOG4105VCD cytoplasmic protein E3384_16030 ENOG4105D22 carbon starvation protein E3384_16035 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) E3384_16040 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase E3384_16045 ENOG4105WQI isochorismatase E3384_16050 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase E3384_16055 ENOG4105E4F Isochorismate synthase E3384_16060 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein E3384_16065 ENOG4105E8G Major facilitator Superfamily E3384_16070 ENOG4105DQ5 transport system permease protein E3384_16075 ENOG4105TVJ transport system, permease E3384_16080 ENOG4105E0A ABC, transporter E3384_16085 ENOG4108QY5 Ferric enterobactin transport protein E3384_16090 ENOG4105C0W non-ribosomal peptide synthetase E3384_16095 ENOG41085A6 mbth domain-containing protein E3384_16100 ENOG4105E93 esterase E3384_16105 ENOG4107RNH Outer membrane receptor FepA E3384_16110 ENOG4108TSE Transferase E3384_16120 ENOG4105WQ6 Membrane E3384_16125 ENOG4105HFT AraC family transcriptional regulator E3384_16130 ENOG41067SE Tetr family transcriptional regulator E3384_16135 ENOG4105MSB protein, conserved in bacteria E3384_16140 ENOG4108RCM Nitroreductase E3384_16160 ENOG4105F3R pts system mannose fructose sorbose family iid E3384_16170 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine E3384_16175 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family E3384_16185 ENOG4105CUY Mechanosensitive ion channel E3384_16190 ENOG4105C85 amino acid E3384_16200 ENOG4108KBJ Inner membrane protein YkgB E3384_16205 ENOG41066GK UPF0379 protein ykgI E3384_16210 ENOG4107QN2 dihydrolipoyl dehydrogenase E3384_16215 ENOG4108K01 transcriptional regulator E3384_16220 ENOG4108IJF Heavy metal efflux pump, CzcA E3384_16225 ENOG4105GR3 Histidine kinase E3384_16235 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) E3384_16240 ENOG4105CKK Glycosyl transferase, family 2 E3384_16265 ENOG4105CKK Glycosyl transferase, family 2 E3384_16270 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) E3384_16285 ENOG4108KU3 Integrase E3384_16300 ENOG4106KCD HTH_LUXR E3384_16310 ENOG4106721 fimbriae Y protein E3384_16315 ENOG4108Q9V regulatoR E3384_16320 ENOG4108ZI2 Fimbrial protein E3384_16325 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) E3384_16330 ENOG4105CW0 outer membrane usher protein E3384_16335 ENOG4108AF8 Chaperone E3384_16345 ENOG4108WDE Fimbrial protein E3384_16360 ENOG4105WQ3 Rna-binding protein E3384_16365 ENOG4105S2T inner membrane protein YbcI E3384_16385 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) E3384_16395 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) E3384_16400 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit E3384_16405 ENOG4105C5B carbamate kinase E3384_16410 ENOG4105G5A Protein of unknown function (DUF2877) E3384_16415 ENOG4107REC cytoplasmic protein E3384_16420 ENOG4107R1Q Membrane protein FdrA E3384_16425 ENOG4105DG4 malate L-lactate dehydrogenase E3384_16430 ENOG4105CE7 Amidase, hydantoinase carbamoylase family E3384_16435 ENOG4105S0E allantoin catabolism protein E3384_16440 ENOG4105BZW Glycerate kinase E3384_16445 ENOG4105DTE Xanthine uracil vitamin C permease E3384_16455 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease E3384_16465 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase E3384_16470 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) E3384_16475 ENOG41060W2 glyoxylate carboligase E3384_16500 ENOG4108UMI ABC transporter, permease E3384_16505 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) E3384_16510 ENOG4105D01 (LipO)protein E3384_16520 ENOG4105CV6 ABC transporter, permease E3384_16525 ENOG4108I0Y (ABC) transporter E3384_16530 ENOG4108UJV acyl-CoA thioesterase i E3384_16535 ENOG4105E1F short-chain dehydrogenase reductase E3384_16540 ENOG4107QR8 Thioredoxin E3384_16545 ENOG4105C4B ABC transporter, permease E3384_16550 ENOG41083J0 (ABC) transporter E3384_16555 ENOG4107QX8 SPFH domain, Band 7 family protein E3384_16560 ENOG4105G5H Membrane E3384_16565 ENOG4108Z6Z Transcriptional regulator E3384_16570 ENOG4105C59 p-type ATPase E3384_16580 ENOG4105MBR gumn family E3384_16585 ENOG4108Z66 YbaK ebsC protein E3384_16590 ENOG4105CGH 5'-nucleotidase E3384_16595 ENOG4105EU0 Major facilitator Superfamily E3384_16600 ENOG4105CKD glutathione-regulated potassium-efflux system protein E3384_16605 ENOG4107RE1 Inosine-guanosine kinase E3384_16640 ENOG4107QMP dna polymerase iii subunits gamma and tau E3384_16650 ENOG4105WD1 Membrane E3384_16655 ENOG4108URS primosomal replication protein n'' E3384_16660 ENOG4106428 Protein of unknown function (DUF2496) E3384_16665 ENOG4105DNE Transposase E3384_16670 ENOG4105EGS Mechanosensitive ion channel E3384_16675 ENOG4108IG5 Transcriptional regulator E3384_16680 ENOG4105C1P efflux transporter, rnd family, mfp subunit E3384_16685 ENOG4105BZS acriflavin resistance protein E3384_16690 ENOG4108UKR Biofilm formation regulator YbaJ E3384_16700 ENOG4108UW5 maltose o-acetyltransferase E3384_16705 ENOG4105GSJ Inner membrane protein ylaC E3384_16720 ENOG41066DG (EAL) domain protein E3384_16730 ENOG41080UX Methyltransferase E3384_16735 ENOG4108MNP Glycoprotein polysaccharide metabolism E3384_16740 ENOG4105C29 acyl-CoA thioesterase E3384_16745 ENOG4105BZU Histidine kinase E3384_16750 ENOG4108YZA Nitrogen regulatory protein pii E3384_16755 ENOG4105BZ1 (ABC) transporter E3384_16760 ENOG4105BZ1 (ABC) transporter E3384_16765 ENOG4108XM1 transcriptional regulator AsnC family E3384_16780 ENOG4108NFA extracellular solute-binding protein E3384_16790 ENOG4108TGP Thioesterase superfamily protein E3384_16795 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein E3384_16800 ENOG4105EIN peptidylprolyl cis-trans isomerase E3384_16805 ENOG4105K70 DNA-binding protein E3384_16810 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) E3384_16835 ENOG4105M85 Bola protein E3384_16840 ENOG4105IEY (LipO)protein E3384_16845 ENOG4105EYM Major Facilitator superfamily E3384_16850 ENOG4105E2S oxidase) subunit II E3384_16855 ENOG4105BZ9 Cytochrome C oxidase, subunit I E3384_16860 ENOG4105CCU oxidase (Subunit III) E3384_16865 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) E3384_16885 ENOG4107RDB Major Facilitator E3384_16895 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) E3384_16900 ENOG4107S0N DJ-1 family E3384_16905 ENOG4108KAZ Involved in phosphonate degradation (By similarity) E3384_16915 ENOG4106S9K Transcriptional regulator E3384_16925 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) E3384_16930 ENOG4108MP3 ABC transporter, permease E3384_16935 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component E3384_16950 ENOG4105CTB Polyprenyl synthetase E3384_16960 ENOG4105CPC Aldo Keto reductase E3384_16965 ENOG4108ZAI phosphatidylglycerophosphatase a E3384_16970 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) E3384_16975 ENOG4107YIM Involved in the transcription termination process (By similarity) E3384_16985 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) E3384_16995 ENOG4108KIC (LipO)protein E3384_17000 ENOG4105DRB nucleoside-specific channel-forming protein E3384_17015 ENOG4105N1F Hnh endonuclease E3384_17030 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) E3384_17040 ENOG4105VIE preprotein translocase, subunit YajC E3384_17060 ENOG4105D3R alkyl hydroperoxide reductase E3384_17065 ENOG4107R28 alpha amylase, catalytic region E3384_17070 ENOG4105C85 amino acid E3384_17075 ENOG4105CWM branched-chain amino acid transport system II carrier protein E3384_17080 ENOG4105BZU Histidine kinase E3384_17085 ENOG4105CK6 Two component transcriptional regulator (Winged helix family E3384_17090 ENOG4107RH8 nuclease SbcCD subunit D E3384_17095 ENOG4105EYH Exonuclease E3384_17100 ENOG4105F27 Major Facilitator E3384_17105 ENOG4105DKQ ROK family E3384_17120 ENOG4105HBA AroM protein E3384_17125 ENOG4105SS3 E3384_17140 ENOG4105II7 pyrroline-5-carboxylate reductase E3384_17145 ENOG4105BZU Histidine kinase E3384_17150 ENOG4105VIF phosphate starvation-inducible protein E3384_17170 ENOG4105CPF Cell wall formation (By similarity) E3384_17175 ENOG4105UNH Membrane E3384_17180 ENOG4105FR5 inner membrane protein YaiY E3384_17185 ENOG4107QS8 (LipO)protein E3384_17190 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 E3384_17200 ENOG4107R6D beta-lactam binding protein AmpH E3384_17205 ENOG4108PNB DNA-binding transcriptional regulator E3384_17210 ENOG4108NSE outer membrane autotransporter barrel E3384_17215 ENOG4105D52 delta-aminolevulinic acid dehydratase E3384_17220 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) E3384_17225 ENOG4105DXD 2-methylcitrate dehydratase E3384_17230 ENOG4105BZN citrate synthase E3384_17235 ENOG4105CR4 methylisocitrate lyase E3384_17240 ENOG4108JU7 Transcriptional regulator E3384_17245 ENOG4105TDT uncharacterized protein yahO E3384_17250 ENOG4105E82 cytochrome subunit of dehydrogenase E3384_17270 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii E3384_17275 ENOG4105C4M (Ubiquinol oxidase) subunit I E3384_17285 ENOG4105D8D Type III E3384_17290 ENOG4107QMH DNA methylase E3384_17295 ENOG4105JHE Major Facilitator Superfamily E3384_17315 ENOG4105C1P efflux transporter, rnd family, mfp subunit E3384_17325 ENOG4105ENJ RND efflux system, outer membrane lipoprotein E3384_17345 ENOG4108T1M outer membrane protein x E3384_17360 ENOG4107XTP (EAL) domain protein E3384_17375 ENOG4105X0I Fimbrial E3384_17380 ENOG4108VEV chaperone E3384_17385 ENOG4105CW0 outer membrane usher protein E3384_17410 ENOG4105EJC lysr family transcriptional regulator E3384_17420 ENOG4105ERH Fumarylacetoacetate hydrolase E3384_17425 ENOG4108TFY Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) E3384_17430 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) E3384_17435 ENOG4105D94 Major Facilitator Superfamily E3384_17440 ENOG4105V2F Uncharacterized protein yoac E3384_17445 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit E3384_17450 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit E3384_17480 ENOG4105FCK Membrane E3384_17500 ENOG4105CIN aminoacyl-histidine dipeptidase E3384_17505 ENOG4108S2Y peptide Chain Release factor E3384_17520 ENOG4105F7V ErfK ybiS ycfS ynhG family protein E3384_17525 ENOG4105E7A Glutamine amidotransferase E3384_17535 ENOG4107QPN acyl-Coa dehydrogenase E3384_17540 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase E3384_17550 ENOG4105T40 surface antigen msp4 family protein E3384_17570 ENOG4108XM1 transcriptional regulator AsnC family E3384_17615 ENOG4105W7K Transcriptional regulator E3384_17670 ENOG4108P8R E3384_17700 ENOG4105TS0 gtp-binding protein E3384_17710 ENOG4108KZE transcriptional regulator E3384_17745 ENOG4106H6R UPF0380 protein E3384_17760 ENOG4106549 Antirestriction protein E3384_17765 ENOG4108XS9 dna repair protein E3384_17775 ENOG4105ZS6 Protein of unknown function (DUF987) E3384_17785 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles E3384_17820 ENOG4108JDX DNA polymerase iii, epsilon subunit E3384_17830 ENOG4105D1A Methyltransferase E3384_17840 ENOG4105E9H Lytic Murein transglycosylase E3384_17845 ENOG4105F2W methyltransferase E3384_17855 ENOG4105F27 Major Facilitator E3384_17860 ENOG4105HEI LysR family (Transcriptional regulator E3384_17865 ENOG4105CV8 reductase E3384_17900 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase E3384_17905 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) E3384_17910 ENOG4108UMI ABC transporter, permease E3384_17915 ENOG4105D01 (LipO)protein E3384_17920 ENOG4108R8X outer membrane lipoprotein E3384_17925 ENOG4108R96 Methyltransferase, YaeB family E3384_17935 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion E3384_17940 ENOG4108YZN class I peptide chain release factor E3384_17945 ENOG4108VWS Yaeq family E3384_17955 ENOG4105M1T rho-binding antiterminator E3384_17960 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) E3384_17965 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase E3384_17970 ENOG4105CXN decarboxylase E3384_17975 ENOG4108M1A Chitin-binding protein E3384_17985 ENOG4105C0B DNA polymerase III (alpha subunit) E3384_18030 ENOG4105KNE Phosphatidate cytidylyltransferase E3384_18065 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) E3384_18080 ENOG4105CSH Transporter E3384_18090 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR E3384_18095 ENOG4105C0H protease E3384_18110 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) E3384_18115 ENOG4105EN6 Membrane E3384_18135 ENOG4106RDH Protein of unknown function (DUF2544) E3384_18145 ENOG4105UGQ Fimbrial E3384_18150 ENOG4105NEV Fimbrial E3384_18155 ENOG4108FZ9 Chaperone E3384_18160 ENOG4106PG1 outer membrane usher protein E3384_18175 ENOG4105S6R Iron-hydroxamate transporter permease subunit E3384_18180 ENOG4105J76 Periplasmic binding protein E3384_18185 ENOG4105E0A ABC, transporter E3384_18190 ENOG4105E0K tonB-dependent siderophore receptor E3384_18195 ENOG4105BZ4 penicillin-binding protein E3384_18200 ENOG4105CQ7 ATP-dependent helicase E3384_18205 ENOG4107XID 2'-5' rna ligase E3384_18215 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters E3384_18220 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) E3384_18225 ENOG4105DJ0 Poly(A) Polymerase E3384_18230 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase E3384_18255 ENOG4108VEV chaperone E3384_18260 ENOG4105CW0 outer membrane usher protein E3384_18265 ENOG4108XEY fimbrial-like adhesin protein E3384_18285 ENOG4107BJW polysaccharide deacetylase E3384_18290 ENOG4108YTN IIa component E3384_18300 ENOG4108UIF Chaperone E3384_18305 ENOG4105CW0 outer membrane usher protein E3384_18310 ENOG4108MDY Fimbrial E3384_18315 ENOG4105E3A (ABC) transporter E3384_18320 ENOG4105DA5 (ABC) transporter E3384_18325 ENOG41077A9 carbonic anhydrase E3384_18330 ENOG4108UGV hypoxanthine phosphoribosyltransferase E3384_18335 ENOG4105DZG Dehydrogenase E3384_18340 ENOG4105E3B Multicopper oxidase E3384_18345 ENOG4108ZRK uncharacterized protein yacC E3384_18360 ENOG4105MVE transcriptional regulator E3384_18365 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) E3384_18370 ENOG4107S2N Type III effector Hrp-dependent E3384_18375 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) E3384_18390 ENOG4106HGK Inner membrane protein yieI E3384_18395 ENOG4107QIJ Aconitate hydratase 2 E3384_18425 ENOG4107QIJ Aconitate hydratase 2 E3384_18430 ENOG4108NST exported protein E3384_18445 ENOG4107QN2 dihydrolipoyl dehydrogenase E3384_18450 ENOG4107QSN dihydrolipoamide acetyltransferase E3384_18455 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) E3384_18460 ENOG41073TP transcriptional regulator E3384_18465 ENOG4105C85 amino acid E3384_18470 ENOG4105CT4 transporter E3384_18475 ENOG4105CUK Alpha-N-arabinofuranosidase (EC 3.2.1.55) E3384_18480 ENOG4106A72 regulatory protein AmpE E3384_18490 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase E3384_18500 ENOG4108ZUW Major pilin subunit E3384_18505 ENOG4107QHF type ii secretion system protein e E3384_18510 ENOG4105D7Q type ii secretion system E3384_18520 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) E3384_18545 ENOG4105M6F mutator MutT protein E3384_18555 ENOG4108SR7 Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity) E3384_18565 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) E3384_18570 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) E3384_18575 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) E3384_18580 ENOG4105CPF Cell wall formation (By similarity) E3384_18595 ENOG4105CNI cell division protein FtsW E3384_18610 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) E3384_18620 ENOG4105CJN penicillin-binding protein E3384_18625 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) E3384_18640 ENOG4107B7Y DNA-binding transcriptional regulator FruR E3384_18645 ENOG4108ZP8 Acetolactate synthase small subunit E3384_18650 ENOG4105C7K acetolactate synthase E3384_18655 ENOG41064T2 transcriptional regulator, lysR family E3384_18680 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) E3384_18695 ENOG4105DP9 ABC transporter E3384_18700 ENOG4106SMU thiamine transporter membrane protein E3384_18705 ENOG4107T0D ABC, transporter E3384_18710 ENOG4108KF1 Membrane E3384_18715 ENOG41063TF transcriptional regulator (AraC E3384_18720 ENOG4105EF1 ribulokinase E3384_18730 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase E3384_18750 ENOG4105CQ2 DNA polymerase E3384_18760 ENOG4105D3G Pseudouridine synthase E3384_18770 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) E3384_18780 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) E3384_18805 ENOG4105CKD glutathione-regulated potassium-efflux system protein E3384_18810 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF E3384_18835 ENOG4105M5B (LipO)protein E3384_18840 ENOG4105C54 Major Facilitator superfamily E3384_18845 ENOG4105WQV ferredoxin-like protein E3384_18850 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase E3384_18900 ENOG4108XNW Transcriptional activatory protein CaiF E3384_18905 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain E3384_18910 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain E3384_18920 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) E3384_18935 ENOG4105CHY citrate lyase, alpha E3384_18940 ENOG4105CI0 Citrate lyase E3384_18950 ENOG4105DUA (citrate (pro-3S)-lyase ligase E3384_18960 ENOG4106AFN Lyase and sodium transporter (By similarity) E3384_18965 ENOG4107QSA Oxaloacetate decarboxylase E3384_18970 ENOG4105D9Q decarboxylase (Beta subunit) E3384_18975 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism E3384_18980 ENOG4106YYS transcriptional regulatory protein E3384_19000 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase E3384_19010 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) E3384_19015 ENOG4105DTN riboflavin biosynthesis protein ribF E3384_19020 ENOG410647N response to DNA damage stimulus E3384_19040 ENOG41063Z6 transcriptional regulator, lysR family E3384_19060 ENOG4105C4X radical SAM domain protein E3384_19065 ENOG41061MV Arylsulfatase E3384_19075 ENOG4105CGH 5'-nucleotidase E3384_19090 ENOG4105DQS Transcriptional regulator E3384_19110 ENOG4106PH7 chaperone E3384_19125 ENOG4105MHR Fimbrial protein E3384_19130 ENOG4105CW0 outer membrane usher protein E3384_19135 ENOG4108AF8 Chaperone E3384_19195 ENOG4108QUJ UPF0174 protein YaaW E3384_19200 ENOG4106HK8 GPR1 FUN34 yaaH family protein E3384_19205 ENOG4108RIR Molybdenum cofactor biosynthesis protein E3384_19215 ENOG4105BZG amino acid carrier protein E3384_19225 ENOG4105D98 threonine synthase E3384_19235 ENOG4105CFH Aspartokinase E3384_19245 ENOG4106FVC RNA methyltransferase E3384_19250 ENOG410759A E3384_19255 ENOG41065U4 response regulator E3384_19265 ENOG4108PNB DNA-binding transcriptional regulator E3384_19275 ENOG4108VCD Chaperone E3384_19280 ENOG4105CW0 outer membrane usher protein E3384_19295 ENOG4105CT7 inner membrane cred family protein E3384_19300 ENOG4105EB3 Histidine kinase E3384_19305 ENOG4105E3W Two component transcriptional regulator (Winged helix family E3384_19310 ENOG4108RH0 Crea protein E3384_19315 ENOG4105UEI Transcriptional Regulator AraC Family E3384_19335 ENOG4107SC1 transglycosylase E3384_19340 ENOG4105C5H ABC transporter E3384_19345 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase E3384_19350 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) E3384_19355 ENOG4105EAC phosphoserine phosphatase E3384_19360 ENOG41062Z9 Membrane E3384_19375 ENOG4105UMR response to DNA damage stimulus E3384_19380 ENOG4108S1B Periplasmic chaperone protein E3384_19385 ENOG4105E6S usher protein( E3384_19415 ENOG4105G0K glycine radical enzyme YjjI family E3384_19420 ENOG41076CZ activating enzyme E3384_19425 ENOG4105EYA deoxyribonuclease E3384_19430 ENOG4108NRW Phospholipase, patatin family E3384_19440 ENOG4105K3G Periplasmic Protein E3384_19450 ENOG4105PAD Hydrolase E3384_19455 ENOG4105KEG ribosomal-protein-alanine acetyltransferase E3384_19460 ENOG4108WPU DNA polymerase III subunit psi E3384_19485 ENOG4105YBH Protein of unknown function (DUF1435) E3384_19490 ENOG4105BZU Histidine kinase E3384_19495 ENOG4108819 ferric iron reductase E3384_19500 ENOG4108UIN ybak prolyl-trna synthetase associated region E3384_19505 ENOG4108T94 DNA-binding transcriptional activator BglJ E3384_19510 ENOG4108N8T regulatoR E3384_19515 ENOG4105DWK Membrane E3384_19530 ENOG4106CVF DNA replication protein E3384_19535 ENOG4105RI1 glycoprotein receptor E3384_19545 ENOG4105C8Q Methyl-accepting chemotaxis E3384_19550 ENOG4105D22 carbon starvation protein E3384_19555 ENOG4105VCD cytoplasmic protein E3384_19560 ENOG4105CKI cobalamin synthesis protein E3384_19605 ENOG4105CVR type I restriction-modification system E3384_19610 ENOG4105EKX Restriction modification system DNA (Specificity E3384_19615 ENOG4105DZR Type I site-specific deoxyribonuclease E3384_19620 ENOG4108HFV E3384_19635 ENOG4105C26 Dehydrogenase E3384_19640 ENOG4105DNE Transposase E3384_19645 ENOG41083G8 Multidrug resistance protein MdtM E3384_19650 ENOG4106BRA Membrane E3384_19655 ENOG4105CBP Major Facilitator E3384_19660 ENOG41074DU domain protein E3384_19665 ENOG4108P2H Inner membrane protein YjiG E3384_19670 ENOG4105DYB Isoaspartyl dipeptidase E3384_19675 ENOG4107YNJ LysR family Transcriptional regulator E3384_19695 ENOG4105C6F GntR Family Transcriptional Regulator E3384_19720 ENOG4105KZM cytoplasmic protein E3384_19725 ENOG4105YCT UPF0386 protein E3384_19730 ENOG4105DTA methyltransferase E3384_19735 ENOG4105CDY transcriptional regulatory protein E3384_19795 ENOG4105ZTC transcriptional activator, Ogr delta E3384_19835 ENOG4105DQ4 alcohol dehydrogenase E3384_19840 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family E3384_19845 ENOG4105CPQ Dehydrogenase E3384_19850 ENOG4105CHR reductase E3384_19855 ENOG4105C6Z Gluconate E3384_19860 ENOG4105K2J Transcriptional regulator E3384_19865 ENOG4108K5H permease YjgP YjgQ family protein E3384_19870 ENOG4108M8S permease YjgP YjgQ family protein E3384_19880 ENOG4105MYG DNA polymerase iii, chi subunit E3384_19885 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) E3384_19890 ENOG4108M3P Membrane E3384_19895 ENOG4108MJ3 acetyltransferase E3384_19905 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase E3384_19910 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) E3384_19915 ENOG4105DBV ornithine carbamoyltransferase E3384_19920 ENOG4105XEP YhcH YjgK YiaL family protein E3384_19930 ENOG4105C5B carbamate kinase E3384_19935 ENOG4105DBV ornithine carbamoyltransferase E3384_19940 ENOG4105CSX c4-dicarboxylate anaerobic carrier E3384_19945 ENOG410682Y Regulates arginine biosynthesis genes (By similarity) E3384_19955 ENOG41077AM PyrBI operon attenuator E3384_19970 ENOG4105KME endoribonuclease L-psp E3384_19985 ENOG4105D4X repressor E3384_19990 ENOG4105C5Y PTS System E3384_19995 ENOG4105CG3 alpha amylase, catalytic region E3384_20000 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase E3384_20005 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) E3384_20010 ENOG4105K4U addiction module toxin, RelE StbE family E3384_20020 ENOG4105EMD TRANSCRIPTIONal E3384_20035 ENOG41069H0 dihydroorotase EC 3.5.2.3 E3384_20065 ENOG4108XVM Cytochrome b(562) E3384_20070 ENOG4105CMS peptidase U62, modulator of DNA gyrase E3384_20080 ENOG4105F0H myo-inositol catabolism protein E3384_20090 ENOG4105IE8 Alpha-ketoglutarate permease E3384_20095 ENOG4105CK5 oxidoreductase E3384_20100 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) E3384_20105 ENOG4105D7K pfkb domain protein E3384_20115 ENOG4107VG4 Xylose isomerase domain protein TIM barrel E3384_20120 ENOG4108MYR Secreted protein E3384_20145 ENOG4105C26 Dehydrogenase E3384_20150 ENOG4105DH8 myo-inositol catabolism E3384_20155 ENOG4107QNK )-transporter E3384_20160 ENOG4107QNK )-transporter E3384_20165 ENOG4105CHC glucokinase (EC 2.7.1.2) E3384_20170 ENOG4105DFU Cell wall formation (By similarity) E3384_20180 ENOG4105F0N pyrophosphate phospho-hydrolase E3384_20185 ENOG41069H0 dihydroorotase EC 3.5.2.3 E3384_20190 ENOG4105DJB Major Facilitator Superfamily E3384_20195 ENOG4108ZHD aig2 family E3384_20215 ENOG4105C37 (CBS) domain E3384_20220 ENOG41061GZ Protein of unknown function (DUF1107) E3384_20225 ENOG4108UUE Transcriptional regulator E3384_20230 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase E3384_20235 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic E3384_20240 ENOG4105KVH Transcriptional regulator E3384_20245 ENOG4105ECR NmrA family E3384_20250 ENOG4105DXC membrane E3384_20265 ENOG4108V1T peptidylprolyl cis-trans isomerase E3384_20270 ENOG4105FHY Opacity-associated protein A E3384_20285 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) E3384_20295 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) E3384_20310 ENOG4105KIT UPF0379 protein yjfY E3384_20340 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC E3384_20355 ENOG4108MXZ Esterase E3384_20360 ENOG4105WSB biofilm stress and motility protein A E3384_20365 ENOG4105S17 UPF0379 protein yjfN E3384_20370 ENOG4105CSU acyl-Coa dehydrogenase E3384_20375 ENOG4106032 Glutathionylspermidine synthase E3384_20380 ENOG4108KXT Conserved Protein E3384_20385 ENOG4105Z6B inner membrane protein yjfl E3384_20390 ENOG4107VNS Protein of unknown function (DUF2491) E3384_20400 ENOG4108P9J Phage shock protein A E3384_20405 ENOG4105FUX Conserved Protein E3384_20410 ENOG4105C2N RNA methyltransferase TrmH family group 3 E3384_20415 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) E3384_20435 ENOG4105EPW hflc protein E3384_20440 ENOG4107QJR hflk protein E3384_20445 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) E3384_20450 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) E3384_20465 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase E3384_20470 ENOG4105K8N protein family UPF0079, ATPase E3384_20475 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) E3384_20480 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) E3384_20500 ENOG4106TNF Periplasmic binding protein E3384_20520 ENOG4105EGS Mechanosensitive ion channel E3384_20525 ENOG4106CG8 Inner membrane protein YjeO E3384_20530 ENOG4107SC7 Inner membrane transporter yjeM E3384_20535 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) E3384_20540 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) E3384_20545 ENOG4105E33 succinate dehydrogenase E3384_20565 ENOG4105KPY Small multidrug resistance protein E3384_20575 ENOG4106BSU Entericidin B E3384_20590 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein E3384_20595 ENOG4105MTB Uncharacterized protein YjeJ E3384_20600 ENOG4108ZVF (LipO)protein E3384_20615 ENOG4105DVH amino acid E3384_20620 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 E3384_20625 ENOG4108IJ0 Aspartate ammonia-lyase E3384_20630 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter E3384_20645 ENOG4108SIC Transcriptional regulator E3384_20660 ENOG4105SBG acid phosphatase E3384_20755 ENOG41068CG regulatoR E3384_20770 ENOG4108ZK4 sdia-regulated domain-containing protein E3384_20780 ENOG4108NEM leader-binding protein dmsD E3384_20785 ENOG4107KGK dmso reductase anchor subunit E3384_20790 ENOG4105QAX Iron-sulfur E3384_20795 ENOG4107QY8 reductase E3384_20800 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism E3384_20805 ENOG4108MRH transcriptional regulatory protein E3384_20815 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter E3384_20820 ENOG4107GFK fumarate E3384_20825 ENOG4105CT4 transporter E3384_20830 ENOG4105F8D glycoside hydrolase family 4 E3384_20835 ENOG4108K2B transcriptional regulator E3384_20840 ENOG4105CXN decarboxylase E3384_20845 ENOG4106ZGR Transcriptional regulator E3384_20850 ENOG4105D5Q Arginine ornithine antiporter E3384_20855 ENOG4105DIJ Phosphoethanolamine transferase E3384_20860 ENOG4105XJC Two component transcriptional regulator (Winged helix family E3384_20865 ENOG4105ECM Sensor protein basS pmrB E3384_20875 ENOG4105CSH Transporter E3384_20880 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA E3384_20885 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase E3384_20890 ENOG410870W N-acetyltransferase E3384_20905 ENOG41082ND Uncharacterized protein yjcO E3384_20910 ENOG4105CK2 sodium dicarboxylate symporter E3384_20915 ENOG4108W0S formate-dependent nitrite reductase complex E3384_20925 ENOG4108QKW cytochrome c-type biogenesis protein E3384_20930 ENOG4105DVI reductase, NrfD E3384_20935 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein E3384_20940 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit E3384_20950 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) E3384_20955 ENOG41062QD Membrane E3384_20965 ENOG41067MG lrgb family E3384_20975 ENOG4105CMU LysR family (Transcriptional regulator E3384_20980 ENOG4105EEQ Na H antiporter E3384_20985 ENOG4105C7N Xanthine uracil vitamin C permease E3384_20995 ENOG4108Z4X TRANSCRIPTIONal E3384_21000 ENOG4108W3Q Transcriptional regulator E3384_21005 ENOG4108M8H domain protein E3384_21010 ENOG4105PMV Membrane E3384_21045 ENOG4108UUM single-stranded DNA-binding protein E3384_21050 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) E3384_21065 ENOG4105MSB protein, conserved in bacteria E3384_21070 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme E3384_21075 ENOG4105F0S class B acid phosphatase E3384_21080 ENOG4105CGF Aromatic amino acid aminotransferase E3384_21085 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) E3384_21090 ENOG4105CDU Replicative dna helicase E3384_21095 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein E3384_21100 ENOG4105P4Z Phage shock protein G E3384_21105 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) E3384_21115 ENOG4105MYN Zinc uptake regulation protein E3384_21120 ENOG4105VDW Csbd family E3384_21130 ENOG4107R73 Mate efflux family protein E3384_21140 ENOG41080IJ Diacylglycerol kinase E3384_21160 ENOG4107W52 maltose operon periplasmic protein E3384_21180 ENOG4107FKK extracellular solute-binding protein family 1 E3384_21185 ENOG4105D56 permease protein E3384_21190 ENOG4105EG2 ABC transporter, permease E3384_21200 ENOG4105E3R (LipO)protein E3384_21205 ENOG4108Q9C Periplasmic Protein E3384_21210 ENOG4108MDC (LipO)protein E3384_21225 ENOG4105CFH Aspartokinase E3384_21255 ENOG4108KP7 hydrolase E3384_21260 ENOG4105E98 transcriptional regulator DeoR family E3384_21265 ENOG4108ZR5 Conserved Protein E3384_21270 ENOG4105FE9 pseudouridine synthase E3384_21275 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme E3384_21285 ENOG4105EQ6 Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity) E3384_21290 ENOG4105EAM Na Pi-cotransporter E3384_21295 ENOG4105C3R Methionine synthase E3384_21300 ENOG41069M3 Transcriptional regulator E3384_21315 ENOG4108I9X Isocitrate lyase E3384_21320 ENOG4107QP3 malate synthase g E3384_21330 ENOG4105K5X acetyltransferase E3384_21360 ENOG4105C12 Phosphoribosylglycinamide synthetase E3384_21365 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family E3384_21370 ENOG4105BZU Histidine kinase E3384_21380 ENOG4108T8B Protein of unknown function (DUF1481) E3384_21385 ENOG4105K70 DNA-binding protein E3384_21390 ENOG4105R2J Conserved Protein E3384_21425 ENOG4105D06 uba thif-type nad fad binding protein E3384_21430 ENOG4105WHD thiamine biosynthesis protein ThiS E3384_21435 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) E3384_21440 ENOG4105D41 biosynthesis protein thiH E3384_21475 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) E3384_21495 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) E3384_21500 ENOG4105PM1 preprotein translocase subunit SecE E3384_21505 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) E3384_21540 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase E3384_21590 ENOG4108Y73 Membrane E3384_21605 ENOG4105C5Q Transcriptional regulator E3384_21640 ENOG4105DIJ Phosphoethanolamine transferase E3384_21645 ENOG4106R3P AraC family transcriptional regulator E3384_21650 ENOG4108XCZ PTS System E3384_21655 ENOG4108AHH pyruvate formate lyase II activase E3384_21660 ENOG4105C6N Formate acetyltransferase E3384_21665 ENOG4108YRF PTS System E3384_21670 ENOG4105DM4 PTS System E3384_21675 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) E3384_21685 ENOG4105DCT glycerol dehydrogenase E3384_21690 ENOG4108XC3 NADH ubiquinone oxidoreductase E3384_21700 ENOG4105SYT Methylenetetrahydrofolate reductase E3384_21705 ENOG4105CGH 5'-nucleotidase E3384_21720 ENOG4105D64 Mechanosensitive ion channel E3384_21725 ENOG4105CFH Aspartokinase E3384_21730 ENOG4105C28 cystathionine E3384_21740 ENOG4108MR7 Arylsulfotransferase E3384_21755 ENOG4105C25 Primosomal protein n' E3384_21760 ENOG4105ETE Transcriptional regulator (LacI family E3384_21765 ENOG41063M6 Cell Division Protein E3384_21780 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase E3384_21790 ENOG4105N4M Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity) E3384_21795 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) E3384_21805 ENOG4105CBT Fructose-1,6-bisphosphatase E3384_21810 ENOG4105DP0 ferredoxin-NADP reductase E3384_21815 ENOG4108VTS Membrane E3384_21820 ENOG4105EBK exported protein E3384_21845 ENOG4105D4B ABC, transporter E3384_21860 ENOG4105C2J ABC transporter E3384_21870 ENOG4107RYS Autoinducer-2 (AI-2) kinase E3384_21880 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) E3384_21900 ENOG4105D7K pfkb domain protein E3384_21905 ENOG4105CT4 transporter E3384_21910 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) E3384_21915 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein E3384_21930 ENOG4105FMW periplasmic E3384_21935 ENOG4105E3W Two component transcriptional regulator (Winged helix family E3384_21940 ENOG4105E0F Histidine kinase E3384_21950 ENOG4108RPX mosc domain containing protein E3384_21955 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) E3384_21960 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit E3384_21965 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter E3384_21970 ENOG4105CG6 trap dicarboxylate transporter dctm subunit E3384_21975 ENOG4108QGT oligogalacturonate-specific porin E3384_22010 ENOG4105C0A alcohol dehydrogenase E3384_22025 ENOG4108UMN azlc family E3384_22035 ENOG4108V87 frv operon regulatory protein E3384_22040 ENOG4108V87 frv operon regulatory protein E3384_22055 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein E3384_22060 ENOG4108MG3 formate dehydrogenase E3384_22075 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system E3384_22085 ENOG4105SUU thioesterase domain E3384_22100 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 E3384_22105 ENOG4105E98 transcriptional regulator DeoR family E3384_22110 ENOG4108MGF sugar kinase E3384_22115 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase E3384_22120 ENOG4105D2M Aldolase E3384_22125 ENOG4107QKS N-acylglucosamine 2-epimerase E3384_22130 ENOG4107WI4 Aldose-1-epimerase E3384_22135 ENOG4105CJQ hydrolase, family 31 E3384_22140 ENOG4105CT4 transporter E3384_22145 ENOG4105CT4 transporter E3384_22150 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is E3384_22180 ENOG4108K4B hydrolase E3384_22190 ENOG4105C5F glutamine synthetase E3384_22195 ENOG4105CUX Signal transduction histidine kinase E3384_22200 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family E3384_22205 ENOG4106FIY E3384_22210 ENOG4105D4P Coproporphyrinogen iii oxidase E3384_22230 ENOG4105C2M dna polymerase I E3384_22235 ENOG4106HNH Acyl-transferase E3384_22250 ENOG4105PC1 Conserved Protein E3384_22255 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) E3384_22260 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b E3384_22290 ENOG4108RR8 protoporphyrinogen oxidase E3384_22295 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) E3384_22300 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein E3384_22320 ENOG4108MR7 Arylsulfotransferase E3384_22325 ENOG4107QK7 reductase E3384_22330 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) E3384_22335 ENOG4105MDZ Transcriptional activator rfaH E3384_22340 ENOG4105F8V Hydrolase, tatD family E3384_22345 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) E3384_22355 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) E3384_22365 ENOG4105JC1 sterol-binding domain protein E3384_22375 ENOG4105CGY Dna recombination protein E3384_22380 ENOG4108I5U Uridine phosphorylase E3384_22385 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) E3384_22390 ENOG4105C4X radical SAM domain protein E3384_22405 ENOG4105DZ2 Transcriptional regulator E3384_22410 ENOG4105EMK carboxylate amino acid amine transporter E3384_22415 ENOG4105DQF Hydrolase E3384_22420 ENOG4108EUD Lysophospholipase E3384_22425 ENOG410829K Lysine exporter protein (Lyse ygga) E3384_22430 ENOG4105CCF Lysine exporter protein (Lyse ygga) E3384_22435 ENOG4105C9U ATP-dependent DNA helicase RecQ E3384_22440 ENOG4105HDD phospholipase E3384_22445 ENOG4108VUY thioesterase Superfamily protein E3384_22450 ENOG4105FR1 rard protein E3384_22455 ENOG4106WR8 Inner membrane protein YigG E3384_22460 ENOG4105NRM Membrane E3384_22470 ENOG4105C4R Atp-dependent dna helicase E3384_22475 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant E3384_22480 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) E3384_22485 ENOG4105CT0 Protein of unknown function, DUF484 E3384_22495 ENOG4105S7Z (LipO)protein E3384_22530 ENOG4107T0K Adenylate cyclase E3384_22540 ENOG41076E6 Uroporphyrinogen-III Synthase E3384_22545 ENOG4105ECF c-methyltransferase E3384_22550 ENOG410601J HemY protein E3384_22575 ENOG4105C85 amino acid E3384_22590 ENOG4105F18 Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity) E3384_22595 ENOG4105EGZ biosynthesis protein E3384_22600 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase E3384_22605 ENOG4108WJ1 acetyltransferase E3384_22610 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) E3384_22615 ENOG4105C1B dTDP-glucose 4-6-dehydratase E3384_22620 ENOG4108IJ1 Dehydrogenase E3384_22625 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase E3384_22630 ENOG4105SFE lipopolysaccharide biosynthesis protein E3384_22635 ENOG4105ESV Glycosyl transferase, family 4 E3384_22645 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) E3384_22655 ENOG4105K63 Thioredoxin E3384_22670 ENOG4105C4R Atp-dependent dna helicase E3384_22675 ENOG4106Z1T Nicotinamide Mononucleotide Transporter E3384_22685 ENOG4105KQ5 peptidylprolyl cis-trans isomerase E3384_22695 ENOG4105EMY transcriptional regulator E3384_22710 ENOG4105C7B Threonine dehydratase E3384_22720 ENOG4105CM2 brancheD-chain amino acid aminotransferase E3384_22725 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit E3384_22740 ENOG4105C0P Mg chelatase subunit ChlI E3384_22785 ENOG4107EJG GntR family transcriptional regulator E3384_22790 ENOG4105C0R drug resistance transporter emrb qaca subfamily E3384_22795 ENOG4105ETE Transcriptional regulator (LacI family E3384_22800 ENOG4108RVA ribokinase E3384_22805 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator E3384_22810 ENOG4105CNN ABC, transporter E3384_22845 ENOG4108VVK transcriptional Regulator, AsnC E3384_22850 ENOG4105QTB Flavodoxin E3384_22865 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation E3384_22875 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) E3384_22905 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) E3384_22920 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) E3384_22925 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) E3384_22930 ENOG4105F9E Shikimate 5-dehydrogenase E3384_22935 ENOG4105DM4 PTS System E3384_22940 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) E3384_22945 ENOG4105C8U phosphate abc transporter E3384_22950 ENOG4105E2Z phosphate ABC transporter (Permease E3384_22965 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 E3384_22970 ENOG4105C7N Xanthine uracil vitamin C permease E3384_22975 ENOG4108YYH Nadph-dependent fmn reductase E3384_22980 ENOG4105E8Q phosphopantetheinyl transferase E3384_23080 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) E3384_23090 ENOG4106CQM replication E3384_23210 ENOG4105XY2 plasmid maintenance protein CcdA E3384_23215 ENOG4105PPN plasmid maintenance protein, CcdB E3384_23255 ENOG4108RAV Conserved protein E3384_23270 ENOG41073YN Protein of unknown function (DUF1380) E3384_23305 ENOG4108UUM single-stranded DNA-binding protein