locus-tag class description D5G00_00005 ENOG4105DBV ornithine carbamoyltransferase D5G00_00010 ENOG4105CSX c4-dicarboxylate anaerobic carrier D5G00_00015 ENOG410682Y Regulates arginine biosynthesis genes (By similarity) D5G00_00025 ENOG41077AM PyrBI operon attenuator D5G00_00040 ENOG4105KME endoribonuclease L-psp D5G00_00060 ENOG4105D4X repressor D5G00_00065 ENOG4105C5Y PTS System D5G00_00070 ENOG4105CG3 alpha amylase, catalytic region D5G00_00075 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase D5G00_00080 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) D5G00_00085 ENOG4105K4U addiction module toxin, RelE StbE family D5G00_00095 ENOG4105EMD TRANSCRIPTIONal D5G00_00110 ENOG41069H0 dihydroorotase EC 3.5.2.3 D5G00_00140 ENOG4108XVM Cytochrome b(562) D5G00_00145 ENOG4105CMS peptidase U62, modulator of DNA gyrase D5G00_00155 ENOG4105DFU Cell wall formation (By similarity) D5G00_00165 ENOG4105F0N pyrophosphate phospho-hydrolase D5G00_00170 ENOG41069H0 dihydroorotase EC 3.5.2.3 D5G00_00175 ENOG4105DJB Major Facilitator Superfamily D5G00_00180 ENOG4108ZHD aig2 family D5G00_00200 ENOG4105C37 (CBS) domain D5G00_00205 ENOG41061GZ Protein of unknown function (DUF1107) D5G00_00215 ENOG4108UUE Transcriptional regulator D5G00_00220 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase D5G00_00230 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic D5G00_00235 ENOG4105KVH Transcriptional regulator D5G00_00240 ENOG4105ECR NmrA family D5G00_00245 ENOG4105DXC membrane D5G00_00270 ENOG4108V1T peptidylprolyl cis-trans isomerase D5G00_00280 ENOG4105FHY Opacity-associated protein A D5G00_00295 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) D5G00_00320 ENOG4105KIT UPF0379 protein yjfY D5G00_00345 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport D5G00_00350 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC D5G00_00365 ENOG4108MXZ Esterase D5G00_00370 ENOG4105WSB biofilm stress and motility protein A D5G00_00375 ENOG4105S17 UPF0379 protein yjfN D5G00_00380 ENOG4105CSU acyl-Coa dehydrogenase D5G00_00385 ENOG4106032 Glutathionylspermidine synthase D5G00_00390 ENOG4108KXT Conserved Protein D5G00_00395 ENOG4105Z6B inner membrane protein yjfl D5G00_00400 ENOG4107VNS Protein of unknown function (DUF2491) D5G00_00410 ENOG4108P9J Phage shock protein A D5G00_00415 ENOG4105FUX Conserved Protein D5G00_00420 ENOG4105C2N RNA methyltransferase TrmH family group 3 D5G00_00425 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) D5G00_00445 ENOG4105EPW hflc protein D5G00_00450 ENOG4107QJR hflk protein D5G00_00455 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) D5G00_00475 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase D5G00_00480 ENOG4105K8N protein family UPF0079, ATPase D5G00_00485 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) D5G00_00490 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) D5G00_00510 ENOG4106TNF Periplasmic binding protein D5G00_00530 ENOG4105EGS Mechanosensitive ion channel D5G00_00535 ENOG4106CG8 Inner membrane protein YjeO D5G00_00540 ENOG4107SC7 Inner membrane transporter yjeM D5G00_00550 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) D5G00_00555 ENOG4105E33 succinate dehydrogenase D5G00_00575 ENOG4105KPY Small multidrug resistance protein D5G00_00585 ENOG4106BSU Entericidin B D5G00_00605 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein D5G00_00610 ENOG4105MTB Uncharacterized protein YjeJ D5G00_00615 ENOG4108ZVF (LipO)protein D5G00_00630 ENOG4105DVH amino acid D5G00_00635 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 D5G00_00640 ENOG4108IJ0 Aspartate ammonia-lyase D5G00_00645 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter D5G00_00655 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) D5G00_00660 ENOG4108SIC Transcriptional regulator D5G00_00675 ENOG4105SBG acid phosphatase D5G00_00715 ENOG4108ZK4 sdia-regulated domain-containing protein D5G00_00725 ENOG4108NEM leader-binding protein dmsD D5G00_00730 ENOG4107KGK dmso reductase anchor subunit D5G00_00735 ENOG4105QAX Iron-sulfur D5G00_00740 ENOG4107QY8 reductase D5G00_00745 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism D5G00_00750 ENOG4108MRH transcriptional regulatory protein D5G00_00760 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter D5G00_00765 ENOG4107GFK fumarate D5G00_00770 ENOG4105CT4 transporter D5G00_00775 ENOG4105F8D glycoside hydrolase family 4 D5G00_00780 ENOG4108K2B transcriptional regulator D5G00_00785 ENOG4105CXN decarboxylase D5G00_00790 ENOG4106ZGR Transcriptional regulator D5G00_00795 ENOG4105D5Q Arginine ornithine antiporter D5G00_00805 ENOG4105XJC Two component transcriptional regulator (Winged helix family D5G00_00810 ENOG4105ECM Sensor protein basS pmrB D5G00_00820 ENOG4105CSH Transporter D5G00_00825 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA D5G00_00830 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase D5G00_00835 ENOG410870W N-acetyltransferase D5G00_00850 ENOG41082ND Uncharacterized protein yjcO D5G00_00855 ENOG4105CK2 sodium dicarboxylate symporter D5G00_00860 ENOG4108W0S formate-dependent nitrite reductase complex D5G00_00865 ENOG4108QKW cytochrome c-type biogenesis protein D5G00_00870 ENOG4105DVI reductase, NrfD D5G00_00875 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein D5G00_00880 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit D5G00_00895 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) D5G00_00905 ENOG41062QD Membrane D5G00_00910 ENOG4107QN1 sodium solute D5G00_00915 ENOG41067MG lrgb family D5G00_00925 ENOG4105CMU LysR family (Transcriptional regulator D5G00_00930 ENOG4105EEQ Na H antiporter D5G00_00940 ENOG4105C7N Xanthine uracil vitamin C permease D5G00_00950 ENOG4108Z4X TRANSCRIPTIONal D5G00_00955 ENOG4108W3Q Transcriptional regulator D5G00_00960 ENOG4108M8H domain protein D5G00_00965 ENOG4105PMV Membrane D5G00_01035 ENOG4108FPN Integrase D5G00_01040 ENOG4108UUM single-stranded DNA-binding protein D5G00_01050 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) D5G00_01065 ENOG4105MSB protein, conserved in bacteria D5G00_01070 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme D5G00_01075 ENOG4105F0S class B acid phosphatase D5G00_01085 ENOG4105CGF Aromatic amino acid aminotransferase D5G00_01090 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) D5G00_01095 ENOG4105CDU Replicative dna helicase D5G00_01100 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein D5G00_01105 ENOG4105P4Z Phage shock protein G D5G00_01110 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) D5G00_01120 ENOG4105MYN Zinc uptake regulation protein D5G00_01125 ENOG4105VDW Csbd family D5G00_01135 ENOG4107R73 Mate efflux family protein D5G00_01145 ENOG41080IJ Diacylglycerol kinase D5G00_01165 ENOG4107W52 maltose operon periplasmic protein D5G00_01180 ENOG4107FKK extracellular solute-binding protein family 1 D5G00_01185 ENOG4105D56 permease protein D5G00_01190 ENOG4105EG2 ABC transporter, permease D5G00_01200 ENOG4105E3R (LipO)protein D5G00_01205 ENOG4108Q9C Periplasmic Protein D5G00_01210 ENOG4108MDC (LipO)protein D5G00_01225 ENOG4105CFH Aspartokinase D5G00_01255 ENOG4108KP7 hydrolase D5G00_01260 ENOG4105E98 transcriptional regulator DeoR family D5G00_01265 ENOG4108ZR5 Conserved Protein D5G00_01270 ENOG4105FE9 pseudouridine synthase D5G00_01275 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme D5G00_01290 ENOG4105EAM Na Pi-cotransporter D5G00_01295 ENOG4105C3R Methionine synthase D5G00_01300 ENOG41069M3 Transcriptional regulator D5G00_01315 ENOG4108I9X Isocitrate lyase D5G00_01320 ENOG4107QP3 malate synthase g D5G00_01330 ENOG4105K5X acetyltransferase D5G00_01365 ENOG4105C12 Phosphoribosylglycinamide synthetase D5G00_01370 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family D5G00_01375 ENOG4105BZU Histidine kinase D5G00_01385 ENOG4108T8B Protein of unknown function (DUF1481) D5G00_01390 ENOG4105K70 DNA-binding protein D5G00_01395 ENOG4105R2J Conserved Protein D5G00_01430 ENOG4105D06 uba thif-type nad fad binding protein D5G00_01435 ENOG4105WHD thiamine biosynthesis protein ThiS D5G00_01445 ENOG4105D41 biosynthesis protein thiH D5G00_01480 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) D5G00_01505 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) D5G00_01510 ENOG4105PM1 preprotein translocase subunit SecE D5G00_01515 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) D5G00_01550 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase D5G00_01555 ENOG4105D4A Cell wall formation (By similarity) D5G00_01600 ENOG4108Y73 Membrane D5G00_01620 ENOG4105C5Q Transcriptional regulator D5G00_01660 ENOG4105DIJ Phosphoethanolamine transferase D5G00_01665 ENOG4106R3P AraC family transcriptional regulator D5G00_01670 ENOG4108XCZ PTS System D5G00_01675 ENOG4108AHH pyruvate formate lyase II activase D5G00_01680 ENOG4105C6N Formate acetyltransferase D5G00_01685 ENOG4108YRF PTS System D5G00_01690 ENOG4105DM4 PTS System D5G00_01695 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) D5G00_01705 ENOG4105DCT glycerol dehydrogenase D5G00_01710 ENOG4108XC3 NADH ubiquinone oxidoreductase D5G00_01720 ENOG4105SYT Methylenetetrahydrofolate reductase D5G00_01735 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) D5G00_01740 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) D5G00_01745 ENOG4105CGH 5'-nucleotidase D5G00_01760 ENOG4105D64 Mechanosensitive ion channel D5G00_01765 ENOG4105CFH Aspartokinase D5G00_01770 ENOG4105C28 cystathionine D5G00_01780 ENOG4108MR7 Arylsulfotransferase D5G00_01795 ENOG4105C25 Primosomal protein n' D5G00_01800 ENOG4105ETE Transcriptional regulator (LacI family D5G00_01805 ENOG41063M6 Cell Division Protein D5G00_01820 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase D5G00_01830 ENOG4105N4M Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity) D5G00_01835 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) D5G00_01845 ENOG4105CBT Fructose-1,6-bisphosphatase D5G00_01850 ENOG4105DP0 ferredoxin-NADP reductase D5G00_01855 ENOG4108VTS Membrane D5G00_01860 ENOG4105EBK exported protein D5G00_01885 ENOG4105D4B ABC, transporter D5G00_01910 ENOG4107RYS Autoinducer-2 (AI-2) kinase D5G00_01920 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) D5G00_01940 ENOG4105D7K pfkb domain protein D5G00_01945 ENOG4105CT4 transporter D5G00_01955 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein D5G00_01970 ENOG4105FMW periplasmic D5G00_01975 ENOG4105E3W Two component transcriptional regulator (Winged helix family D5G00_01980 ENOG4105E0F Histidine kinase D5G00_01990 ENOG4108RPX mosc domain containing protein D5G00_01995 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) D5G00_02000 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit D5G00_02005 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter D5G00_02010 ENOG4105CG6 trap dicarboxylate transporter dctm subunit D5G00_02015 ENOG4108QGT oligogalacturonate-specific porin D5G00_02060 ENOG4105C0A alcohol dehydrogenase D5G00_02075 ENOG4108UMN azlc family D5G00_02085 ENOG4108V87 frv operon regulatory protein D5G00_02090 ENOG4108V87 frv operon regulatory protein D5G00_02100 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) D5G00_02105 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) D5G00_02110 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein D5G00_02115 ENOG4108MG3 formate dehydrogenase D5G00_02130 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system D5G00_02140 ENOG4105RVE Uncharacterized protein conserved in bacteria (DUF2136) D5G00_02145 ENOG4108Z3N Transcriptional regulator D5G00_02150 ENOG4105SUU thioesterase domain D5G00_02165 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 D5G00_02170 ENOG4105E98 transcriptional regulator DeoR family D5G00_02175 ENOG4108MGF sugar kinase D5G00_02180 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase D5G00_02185 ENOG4105D2M Aldolase D5G00_02190 ENOG4107QKS N-acylglucosamine 2-epimerase D5G00_02195 ENOG4107WI4 Aldose-1-epimerase D5G00_02200 ENOG4105CJQ hydrolase, family 31 D5G00_02205 ENOG4105CT4 transporter D5G00_02210 ENOG4105CT4 transporter D5G00_02215 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is D5G00_02245 ENOG4108K4B hydrolase D5G00_02260 ENOG4105C5F glutamine synthetase D5G00_02270 ENOG4105CUX Signal transduction histidine kinase D5G00_02275 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family D5G00_02280 ENOG4106FIY D5G00_02285 ENOG4105D4P Coproporphyrinogen iii oxidase D5G00_02305 ENOG4105C2M dna polymerase I D5G00_02315 ENOG4106HNH Acyl-transferase D5G00_02330 ENOG4105PC1 Conserved Protein D5G00_02335 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) D5G00_02340 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b D5G00_02370 ENOG4108RR8 protoporphyrinogen oxidase D5G00_02375 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) D5G00_02380 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein D5G00_02400 ENOG4108MR7 Arylsulfotransferase D5G00_02405 ENOG4107QK7 reductase D5G00_02410 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) D5G00_02415 ENOG4105MDZ Transcriptional activator rfaH D5G00_02420 ENOG4105F8V Hydrolase, tatD family D5G00_02425 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) D5G00_02435 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) D5G00_02445 ENOG4105JC1 sterol-binding domain protein D5G00_02455 ENOG4105CGY Dna recombination protein D5G00_02460 ENOG4108I5U Uridine phosphorylase D5G00_02465 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) D5G00_02470 ENOG4105C4X radical SAM domain protein D5G00_02480 ENOG4105DZ2 Transcriptional regulator D5G00_02485 ENOG4105EMK carboxylate amino acid amine transporter D5G00_02490 ENOG4105DQF Hydrolase D5G00_02495 ENOG4108EUD Lysophospholipase D5G00_02500 ENOG410829K Lysine exporter protein (Lyse ygga) D5G00_02505 ENOG4105CCF Lysine exporter protein (Lyse ygga) D5G00_02510 ENOG4105C9U ATP-dependent DNA helicase RecQ D5G00_02515 ENOG4105HDD phospholipase D5G00_02520 ENOG4108VUY thioesterase Superfamily protein D5G00_02525 ENOG4105FR1 rard protein D5G00_02550 ENOG4105C4R Atp-dependent dna helicase D5G00_02555 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant D5G00_02560 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) D5G00_02565 ENOG4105CT0 Protein of unknown function, DUF484 D5G00_02575 ENOG4105S7Z (LipO)protein D5G00_02600 ENOG4107T0K Adenylate cyclase D5G00_02610 ENOG41076E6 Uroporphyrinogen-III Synthase D5G00_02615 ENOG4105ECF c-methyltransferase D5G00_02620 ENOG410601J HemY protein D5G00_02645 ENOG4105C85 amino acid D5G00_02665 ENOG4105EGZ biosynthesis protein D5G00_02670 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase D5G00_02675 ENOG4108WJ1 acetyltransferase D5G00_02680 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) D5G00_02680 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) D5G00_02685 ENOG4105C1B dTDP-glucose 4-6-dehydratase D5G00_02690 ENOG4108IJ1 Dehydrogenase D5G00_02695 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase D5G00_02700 ENOG4105SFE lipopolysaccharide biosynthesis protein D5G00_02705 ENOG4105ESV Glycosyl transferase, family 4 D5G00_02710 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) D5G00_02720 ENOG4105K63 Thioredoxin D5G00_02740 ENOG4105C4R Atp-dependent dna helicase D5G00_02745 ENOG4106Z1T Nicotinamide Mononucleotide Transporter D5G00_02755 ENOG4105KQ5 peptidylprolyl cis-trans isomerase D5G00_02765 ENOG4105EMY transcriptional regulator D5G00_02780 ENOG4105C7B Threonine dehydratase D5G00_02790 ENOG4105CM2 brancheD-chain amino acid aminotransferase D5G00_02795 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit D5G00_02810 ENOG4105C0P Mg chelatase subunit ChlI D5G00_02855 ENOG4107EJG GntR family transcriptional regulator D5G00_02860 ENOG4105C0R drug resistance transporter emrb qaca subfamily D5G00_02865 ENOG4105ETE Transcriptional regulator (LacI family D5G00_02870 ENOG4108RVA ribokinase D5G00_02875 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator D5G00_02880 ENOG4105CNN ABC, transporter D5G00_02885 ENOG4105C2J ABC transporter D5G00_02915 ENOG4108VVK transcriptional Regulator, AsnC D5G00_02920 ENOG4105QTB Flavodoxin D5G00_02935 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation D5G00_02945 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) D5G00_02975 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) D5G00_02995 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) D5G00_03000 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) D5G00_03005 ENOG4105F9E Shikimate 5-dehydrogenase D5G00_03015 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) D5G00_03020 ENOG4105C8U phosphate abc transporter D5G00_03025 ENOG4105E2Z phosphate ABC transporter (Permease D5G00_03040 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 D5G00_03045 ENOG4105C7N Xanthine uracil vitamin C permease D5G00_03050 ENOG4108YYH Nadph-dependent fmn reductase D5G00_03055 ENOG4105E8Q phosphopantetheinyl transferase D5G00_03100 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) D5G00_03110 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) D5G00_03120 ENOG4105CXK mandelate racemase muconate lactonizing D5G00_03125 ENOG4105DJB Major Facilitator Superfamily D5G00_03130 ENOG410667J hydrolase D5G00_03135 ENOG4105EMF GntR family transcriptional regulator D5G00_03140 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 D5G00_03145 ENOG4108RTU Aldolase D5G00_03155 ENOG4105DJB Major Facilitator Superfamily D5G00_03160 ENOG4105BZU Histidine kinase D5G00_03165 ENOG4108SV3 Tmao reductase system periplasmic protein tort D5G00_03170 ENOG4106WF9 DNA-binding transcriptional regulator TorR D5G00_03175 ENOG4105CUW cytochrome C-TYPE protein D5G00_03180 ENOG4108EM1 reductase D5G00_03190 ENOG4105CA0 peroxidase D5G00_03195 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) D5G00_03200 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) D5G00_03205 ENOG41060IM Heme exporter protein D5G00_03210 ENOG4105X3C heme exporter protein D5G00_03215 ENOG4108ZKK Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity) D5G00_03220 ENOG4105DA4 cytochrome c-type biogenesis protein D5G00_03225 ENOG4107QX9 Thiol disulfide interChange protein D5G00_03230 ENOG4105KWW Biogenesis protein D5G00_03235 ENOG4105D99 atp gtp-binding protein D5G00_03240 ENOG4105R2A (LipO)protein D5G00_03260 ENOG4105VG5 Membrane D5G00_03265 ENOG4105JP4 Inner membrane protein yidG D5G00_03270 ENOG4105J13 transcriptional regulator D5G00_03285 ENOG4105W8I Transcriptional regulator D5G00_03295 ENOG4105E5M Multidrug resistance protein D D5G00_03325 ENOG4105C7K acetolactate synthase D5G00_03330 ENOG4105M71 acetolactate synthase 1 regulatory subunit D5G00_03335 ENOG4107FB0 transcriptional regulator DeoR family D5G00_03340 ENOG4108RVA ribokinase D5G00_03345 ENOG4105EDR glucose galactose transporter D5G00_03355 ENOG4108KX4 response regulator D5G00_03360 ENOG4105BZU Histidine kinase D5G00_03365 ENOG4105CXY transporter D5G00_03370 ENOG4105CXY transporter D5G00_03375 ENOG4108SAJ Protein of unknown function (DUF1198) D5G00_03395 ENOG4105CS2 ec 3.2.1.21 D5G00_03420 ENOG4108EQA pts system D5G00_03425 ENOG4105ETZ PTS System D5G00_03430 ENOG4105F3R pts system mannose fructose sorbose family iid D5G00_03445 ENOG4105DNE Transposase D5G00_03450 ENOG4108UZ3 Transporter D5G00_03460 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic D5G00_03475 ENOG4105CHJ isochorismatase hydrolase D5G00_03485 ENOG4108TC1 Transcriptional regulator D5G00_03490 ENOG4105FV3 D5G00_03500 ENOG4105ISV protein with bipartite regulator domain D5G00_03550 ENOG4105CJQ hydrolase, family 31 D5G00_03555 ENOG4105JV1 AsmA family D5G00_03560 ENOG4105C2W permease D5G00_03565 ENOG4105D6U Sodium Glutamate Symporter D5G00_03570 ENOG4105CB5 ATP-dependent DNA helicase recG D5G00_03575 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase D5G00_03580 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) D5G00_03585 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) D5G00_03600 ENOG4105EN6 Membrane D5G00_03615 ENOG4105DSJ YicC domain protein D5G00_03645 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase D5G00_03660 ENOG4105W0E 50S ribosomal protein L33 D5G00_03675 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase D5G00_03680 ENOG4105DKP glycosyl transferase, family 9 D5G00_03685 ENOG4107RJ7 Glycosyl transferase (Group 1 D5G00_03690 ENOG4107543 (lipo)polysaccharide D5G00_03705 ENOG4107XU6 Glycosyl transferase (Group 1 D5G00_03710 ENOG4106AH0 Glycosyl Transferase D5G00_03715 ENOG4105X1N Glycosyl transferase family 8 D5G00_03720 ENOG4108PDR lipopolysaccharide core biosynthesis protein D5G00_03730 ENOG4107XB0 Lipopolysaccharide 1,2-N-acetylglucosaminetransferase D5G00_03735 ENOG4108FRV O-antigen ligase D5G00_03740 ENOG4105D16 lipopolysaccharide heptosyltransferase i D5G00_03745 ENOG4105XA0 heptosyltransferase ii D5G00_03755 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) D5G00_03765 ENOG4105K64 Glycosyl transferase, family 2 D5G00_03770 ENOG4105PXI polysaccharide deacetylase D5G00_03775 ENOG41063SB peptidase D5G00_03785 ENOG4107YZP Rhodanese domain protein D5G00_03790 ENOG4105VW4 glutaredoxin 3 D5G00_03805 ENOG4105D7W serine acetyltransferase D5G00_03810 ENOG4105DJB Major Facilitator Superfamily D5G00_03815 ENOG4105DIA mandelate racemase muconate lactonizing D5G00_03825 ENOG4105ETE Transcriptional regulator (LacI family D5G00_03830 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) D5G00_03840 ENOG41073TP transcriptional regulator D5G00_03845 ENOG4105DAA L-lactate D5G00_03850 ENOG4105EUR Domain-Containing protein D5G00_03855 ENOG4108WY4 inner membrane lipoprotein D5G00_03865 ENOG4108YYI Protein of unknown function (DUF2810) D5G00_03875 ENOG4105E61 Mannitol repressor protein D5G00_03885 ENOG4105CTS PTS system mannitol-specific D5G00_03890 ENOG4108U78 Glutathione S-transferase D5G00_03900 ENOG4105EM7 Selenocysteine-specific translation elongation factor D5G00_03905 ENOG41066F8 ROK family D5G00_03910 ENOG4105C26 Dehydrogenase D5G00_03925 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase D5G00_03930 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase D5G00_03935 ENOG4105H6Q decarboxylase D5G00_03940 ENOG4105CMG Carbohydrate kinase D5G00_03945 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit D5G00_03950 ENOG4105CG6 trap dicarboxylate transporter dctm subunit D5G00_03955 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter D5G00_03960 ENOG4108M5W D5G00_03965 ENOG4108R66 Conserved Protein D5G00_03975 ENOG4105J4Q Transcriptional regulator D5G00_03980 ENOG4108XIB electron transport protein ysaA D5G00_03985 ENOG4105JKW Valine--pyruvate aminotransferase D5G00_03990 ENOG4107T9C Alpha amylase catalytic region D5G00_03995 ENOG4108UR8 BAX protein D5G00_04000 ENOG4105T16 Transcriptional regulator (AraC family) D5G00_04015 ENOG4105CMG Carbohydrate kinase D5G00_04020 ENOG410688U Inner membrane protein yiaB D5G00_04025 ENOG4105MEV Acyl-transferase D5G00_04035 ENOG4105RGS lipoprotein ysaB D5G00_04050 ENOG4105DQ6 Transposase D5G00_04075 ENOG4105VEQ Cold shock protein D5G00_04080 ENOG4105MVF Transcriptional regulator D5G00_04085 ENOG4106JH6 (LipO)protein D5G00_04095 ENOG4108ZG0 Ompa motb domain protein D5G00_04100 ENOG4107QY8 reductase D5G00_04105 ENOG4105HNP -acetyltransferase D5G00_04110 ENOG4108R3E Dna-3-methyladenine glycosylase i D5G00_04115 ENOG4105EAX Putative lipase D5G00_04120 ENOG4106EAR Fimbrial protein D5G00_04125 ENOG4108VCD Chaperone D5G00_04130 ENOG4105CW0 outer membrane usher protein D5G00_04135 ENOG4105CW0 outer membrane usher protein D5G00_04140 ENOG4105MHR Fimbrial protein D5G00_04145 ENOG4106UCC Fimbrial protein D5G00_04150 ENOG4105DIJ Phosphoethanolamine transferase D5G00_04170 ENOG4105CQ4 Transcriptional regulator D5G00_04185 ENOG4105DEF Extracellular solute-binding protein, family 5 D5G00_04190 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component D5G00_04195 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component D5G00_04200 ENOG4105C3U ABC transporter D5G00_04205 ENOG4108JQ7 (ABC) transporter D5G00_04210 ENOG4105C44 Serine transporter D5G00_04225 ENOG4105D1V cellulose synthase operon protein YhjU D5G00_04230 ENOG410675P Celllulose biosynthesis operon protein BcsF YhjT D5G00_04240 ENOG410661M cytoplasmic protein D5G00_04245 ENOG4105UTS cellulose synthase operon protein YhjQ D5G00_04250 ENOG4107QZ7 Cellulose synthase catalytic subunit D5G00_04255 ENOG4107EEX Cellulose synthase regulator protein D5G00_04260 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) D5G00_04265 ENOG4105EJG cellulose synthase D5G00_04275 ENOG4105BZU Histidine kinase D5G00_04285 ENOG4105CS0 peptidase D5G00_04290 ENOG4107SS6 2-dehydro-3-deoxygluconokinase D5G00_04295 ENOG4105CMB EAL domain-containing protein D5G00_04300 ENOG41066T0 asmA family D5G00_04305 ENOG4105CSH Transporter D5G00_04310 ENOG4107H3J ribonuclease D5G00_04315 ENOG4105CBN LysR family transcriptional regulator D5G00_04320 ENOG4106S2D Transcriptional regulator D5G00_04340 ENOG4105FDP GntR family transcriptional regulator D5G00_04345 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine D5G00_04350 ENOG4108KPW sugar kinase D5G00_04355 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter D5G00_04365 ENOG4105DC8 reductase D5G00_04370 ENOG4105D6S protein involved in catabolism of external DNA D5G00_04375 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase D5G00_04380 ENOG4105DGW oligopeptidase A D5G00_04390 ENOG4105DUX Transporter D5G00_04395 ENOG4108M6U Universal stress protein A D5G00_04405 ENOG4105CJ3 phosphate transporter D5G00_04410 ENOG4105CBX hi0933 family D5G00_04415 ENOG4105D0S secretion protein (HlyD D5G00_04425 ENOG4105CMI transporter D5G00_04435 ENOG4107YAK holo-(acyl carrier protein) synthase 2 D5G00_04440 ENOG4105DSF transport protein D5G00_04450 ENOG4108W1V Lipoprotein D5G00_04455 ENOG4105EX9 Membrane D5G00_04465 ENOG4105C8Q Methyl-accepting chemotaxis D5G00_04475 ENOG4107FS9 Membrane D5G00_04485 ENOG4105MG3 Membrane D5G00_04490 ENOG4106H78 methyltransferase D5G00_04495 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) D5G00_04500 ENOG4105CAK Cell division ATP-binding protein ftsE D5G00_04505 ENOG4105CRP Part of the ABC transporter FtsEX involved in D5G00_04515 ENOG4105CP9 extracellular ligand-binding receptor D5G00_04525 ENOG4105U59 -acetyltransferase D5G00_04530 ENOG4105CP9 extracellular ligand-binding receptor D5G00_04535 ENOG4105C32 Amino acid ABC transporter (Permease) D5G00_04540 ENOG4105CF8 branched-chain amino acid ABC transporter, permease D5G00_04545 ENOG4105C0Z ABC transporter D5G00_04550 ENOG4108IV0 ABC, transporter D5G00_04555 ENOG41060M8 Pfam:PhdYeFM D5G00_04565 ENOG4105BZ7 extracellular solute-binding protein family 1 D5G00_04570 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component D5G00_04580 ENOG4108IJ9 (ABC) transporter D5G00_04585 ENOG4107T6V glycerophosphoryl diester phosphodiesterase D5G00_04590 ENOG4105WC8 Conserved Protein D5G00_04595 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) D5G00_04600 ENOG41080QX K07048 phosphotriesterase-related protein D5G00_04615 ENOG4108RVA ribokinase D5G00_04620 ENOG4105WCN acetyltransferase D5G00_04625 ENOG4105D9R oxidoreductase D5G00_04630 ENOG4105C2I pirin domain protein D5G00_04635 ENOG4105DIQ Transcriptional regulator D5G00_04640 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family D5G00_04645 ENOG4105C6Z Gluconate D5G00_04650 ENOG41076UM multiple antibiotic resistance (MarC)-related protein D5G00_04655 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) D5G00_04680 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) D5G00_04685 ENOG4107HP6 Transcriptional regulator D5G00_04690 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) D5G00_04695 ENOG4105C01 Dihydroxy-acid dehydratase D5G00_04705 ENOG4105DCT glycerol dehydrogenase D5G00_04720 ENOG4105C6V Glycerol-3-phosphate dehydrogenase D5G00_04735 ENOG4105E98 transcriptional regulator DeoR family D5G00_04740 ENOG4105CYB regulatoR D5G00_04750 ENOG4105E0Y RtcB Protein D5G00_04765 ENOG4105VXN addiction module toxin, RelE StbE family D5G00_04775 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) D5G00_04780 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) D5G00_04785 ENOG4105C6Z Gluconate D5G00_04795 ENOG4105MJ2 Competence protein D5G00_04805 ENOG4105DNE Transposase D5G00_04820 ENOG4105XFK Ferrous iron transport protein A D5G00_04830 ENOG4105BZM domain protein D5G00_04835 ENOG4108RRZ Transcription elongation factor GreB D5G00_04840 ENOG4105DPZ Two component transcriptional regulator (Winged helix family D5G00_04845 ENOG4105E0F Histidine kinase D5G00_04855 ENOG4108MAJ Membrane D5G00_04860 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) D5G00_04865 ENOG4105VEJ Heat shock protein D5G00_04870 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 D5G00_04875 ENOG4105DQY intracellular growth attenuator D5G00_04880 ENOG4107RK2 ADP-ribose diphosphatase NudE D5G00_04885 ENOG4108JQC penicillin-binding protein 1A D5G00_04890 ENOG4108U1Q Pilus assembly protein D5G00_04895 ENOG41065NF Fimbrial assembly family protein D5G00_04900 ENOG4105XPX DNA utilization protein HofO D5G00_04905 ENOG4105ITY Required for the use of extracellular DNA as a nutrient D5G00_04930 ENOG4105EGB membrane protein DamX D5G00_04935 ENOG4105DFE Dna adenine methylase D5G00_04940 ENOG4105DJV ribulose-phosphate 3-epimerase D5G00_04950 ENOG4105C31 Tryptophanyl-tRNA synthetase D5G00_04955 ENOG4105VYH D5G00_04960 ENOG4107EF2 surface-exposed virulence protein D5G00_04975 ENOG4107V9H nitrite transporter D5G00_04980 ENOG4105WZK nitrite reductase NADPH small subunit D5G00_04985 ENOG4107QZF nitrite reductase NADPH large subunit D5G00_04995 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) D5G00_05000 ENOG4106195 uncharacterized protein yhfG D5G00_05005 ENOG4105MZU cell filamentation protein D5G00_05010 ENOG4105DDQ anthranilate synthase D5G00_05015 ENOG4105C8Y Acetylornithine aminotransferase D5G00_05020 ENOG410613R integral membrane protein, YccS YhfK family D5G00_05030 ENOG4108UKZ OsmC family D5G00_05035 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) D5G00_05045 ENOG4105DNZ Alpha Beta Hydrolase D5G00_05055 ENOG4108K70 Transcriptional regulator D5G00_05060 ENOG4105C5H ABC transporter D5G00_05075 ENOG4105VKU nucleicacid-binding protein D5G00_05080 ENOG4108YZY peptidylprolyl cis-trans isomerase D5G00_05095 ENOG4108V1T peptidylprolyl cis-trans isomerase D5G00_05100 ENOG4105WWK YheO domain protein D5G00_05135 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) D5G00_05150 ENOG4105W53 bacterioferritin-associated ferredoxin D5G00_05155 ENOG4108UQY Iron-storage protein D5G00_05160 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) D5G00_05180 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) D5G00_05195 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) D5G00_05200 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) D5G00_05205 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) D5G00_05215 ENOG41083MP 50s ribosomal protein l29 D5G00_05225 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) D5G00_05230 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) D5G00_05245 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) D5G00_05255 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) D5G00_05260 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) D5G00_05265 ENOG4105VPB 50S ribosomal protein L30 D5G00_05270 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) D5G00_05275 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) D5G00_05280 ENOG41067V7 50S ribosomal protein L36 D5G00_05300 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) D5G00_05310 ENOG4105VTS DnaJ-like, subfamily C D5G00_05315 ENOG4105W1Y Transcriptional regulator D5G00_05320 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system D5G00_05330 ENOG4105C1A potassium transporter peripheral membrane D5G00_05350 ENOG4105C79 DNA protecting protein DprA D5G00_05360 ENOG4108WI1 Dna topoisomerase D5G00_05375 ENOG4105SG3 Protein of unknown function (DUF1488) D5G00_05380 ENOG4108Z0R Transferase D5G00_05415 ENOG4105XCM membrane LIPOPROTEIN D5G00_05420 ENOG4105BZS acriflavin resistance protein D5G00_05430 ENOG4108XG4 DNA-binding transcriptional regulator D5G00_05435 ENOG4105BZU Histidine kinase D5G00_05440 ENOG41061ME transport protein D5G00_05445 ENOG4105CEC DNA methylase N-4 N-6 D5G00_05450 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) D5G00_05455 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) D5G00_05465 ENOG4108IA2 Sodium pantothenate symporter D5G00_05470 ENOG4105RG0 Membrane D5G00_05475 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase D5G00_05480 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein D5G00_05495 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family D5G00_05500 ENOG41062P1 Diguanylate cyclase phosphodiesterase D5G00_05510 ENOG4105DFF Rod shape-determining protein mreb D5G00_05515 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) D5G00_05520 ENOG4105VQ7 Rod shape-determining protein MreD D5G00_05530 ENOG4105C03 ribonuclease D5G00_05535 ENOG4105QD6 exported protein D5G00_05540 ENOG4105D1U peptidase U62 modulator of DNA gyrase D5G00_05545 ENOG4105CR8 Transcriptional regulator D5G00_05550 ENOG4105ZQC membrane protein AaeX D5G00_05565 ENOG4105UNR (Barnase) inhibitor D5G00_05570 ENOG4105RID UPF0379 protein yhcN D5G00_05575 ENOG4105RID UPF0379 protein yhcN D5G00_05590 ENOG4105FDP GntR family transcriptional regulator D5G00_05600 ENOG4105C8P )-transporter D5G00_05605 ENOG4106DSS Tartrate dehydratase subunit alpha D5G00_05610 ENOG4107GFK fumarate D5G00_05615 ENOG4107QSA Oxaloacetate decarboxylase D5G00_05620 ENOG4105D9Q decarboxylase (Beta subunit) D5G00_05625 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase D5G00_05635 ENOG4105C0H protease D5G00_05640 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III D5G00_05645 ENOG4105D6Z AFG1 family ATPase D5G00_05670 ENOG4107MKT Stringent starvation protein a D5G00_05675 ENOG4105KB2 stringent starvation protein b D5G00_05705 ENOG4108R66 Conserved Protein D5G00_05710 ENOG4105DZC cytosine deaminase D5G00_05715 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin D5G00_05720 ENOG4105DFS Conserved Protein D5G00_05725 ENOG4105BZ8 glutamate synthase D5G00_05730 ENOG4105CBC glutamate synthase D5G00_05740 ENOG4105N5T Radical SAM Protein D5G00_05745 ENOG4105BZU Histidine kinase D5G00_05750 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain D5G00_05760 ENOG4108NIH transferase activity, transferring phosphorus-containing groups D5G00_05770 ENOG41080Z8 PHOSPHOCARRIER protein D5G00_05780 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN D5G00_05785 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA D5G00_05790 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) D5G00_05795 ENOG4108IUZ ABC transporter D5G00_05800 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA D5G00_05805 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) D5G00_05810 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase D5G00_05815 ENOG4105C2X Arabinose 5-phosphate isomerase D5G00_05820 ENOG4105FEU K -dependent Na -Ca exchanger D5G00_05825 ENOG4105DHJ ABC, transporter D5G00_05830 ENOG4105CY3 ABC transporter, permease D5G00_05835 ENOG4107PE3 Mammalian cell entry related domain protein D5G00_05840 ENOG4105E3I toluene tolerance D5G00_05845 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane D5G00_05850 ENOG4105VFK BolA family D5G00_05860 ENOG4105HVQ Regulatory factor of maltose metabolism D5G00_05865 ENOG4105EAH synthase D5G00_05880 ENOG4105QYV Membrane D5G00_05890 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase D5G00_05895 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) D5G00_05900 ENOG4105HBR Rna-binding protein D5G00_05905 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) D5G00_05915 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) D5G00_05920 ENOG4105EEI dihydropteroate synthase D5G00_05960 ENOG4105CHV Transcription elongation factor NusA D5G00_05995 ENOG4105C1J atp-dependent rna helicase D5G00_06000 ENOG4105CIC tryptophan-specific transport protein D5G00_06010 ENOG4105F7V ErfK ybiS ycfS ynhG family protein D5G00_06015 ENOG4105DEN Luciferase family D5G00_06020 ENOG4106RZ4 Peptidase U32 D5G00_06025 ENOG4105CFP Peptidase U32 D5G00_06030 ENOG4105XPQ lipid carrier protein D5G00_06035 ENOG4108YYD acetyltransferase D5G00_06050 ENOG4107R7Y intracellular protease Pfpi family D5G00_06055 ENOG4105K4T epimerase D5G00_06060 ENOG4105W4M Transport-associated protein D5G00_06075 ENOG4105E1C Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity) D5G00_06080 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) D5G00_06090 ENOG4107WTH Galactitol-1-phosphate dehydrogenase D5G00_06095 ENOG4105DT3 PTS system, galactitol-specific IIc component D5G00_06100 ENOG41090UW PTS System D5G00_06105 ENOG41082GB PTS system galactitol-specific transporter subunit IIA D5G00_06120 ENOG4105CTX dehydratase D5G00_06130 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase D5G00_06135 ENOG4105BZW Glycerate kinase D5G00_06155 ENOG410811B TRANSCRIPTIONal D5G00_06160 ENOG4105C7B Threonine dehydratase D5G00_06175 ENOG4105C6N Formate acetyltransferase D5G00_06180 ENOG4105EJQ L-serine dehydratase D5G00_06195 ENOG4106D80 Uncharacterized protein YhaL D5G00_06200 ENOG4108CNN domain protein D5G00_06205 ENOG4105CWB LysR family transcriptional Regulator D5G00_06210 ENOG4105KAF membrAne D5G00_06220 ENOG4108VBZ doxx family D5G00_06225 ENOG4105YJD D5G00_06230 ENOG41090KG Inner membrane protein YqjE D5G00_06235 ENOG4105NE1 Conserved Protein D5G00_06240 ENOG4105WAY exported protein D5G00_06250 ENOG4106W5V Membrane D5G00_06265 ENOG4105DU1 integral membrane protein, terc D5G00_06270 ENOG4105EE0 oxidoreductase D5G00_06275 ENOG4108UB4 uncharacterized protein ygjQ D5G00_06280 ENOG4108VKG metal-dependent hydrolase D5G00_06290 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase D5G00_06305 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor D5G00_06310 ENOG4105C8Q Methyl-accepting chemotaxis D5G00_06315 ENOG4105NTW Transcriptional regulator D5G00_06320 ENOG4105Q26 Siderophore-interacting protein D5G00_06335 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) D5G00_06340 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) D5G00_06345 ENOG4105VCC 30S ribosomal protein S21 D5G00_06355 ENOG4106DSS Tartrate dehydratase subunit alpha D5G00_06365 ENOG4107ZVW dihydroneopterin aldolase D5G00_06380 ENOG4106MWK domain protein D5G00_06390 ENOG4105I7R Adenylate cyclase D5G00_06410 ENOG4107S78 Band 7 protein D5G00_06415 ENOG4105PV3 Inner membrane protein yqiJ D5G00_06425 ENOG4105W0Z cytoplasmic protein D5G00_06445 ENOG4108MR7 Arylsulfotransferase D5G00_06460 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b D5G00_06465 ENOG4106032 Glutathionylspermidine synthase D5G00_06485 ENOG41087AY ADP-Ribose pyrophosphatase D5G00_06490 ENOG4108SX3 cytoplasmic protein D5G00_06495 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) D5G00_06500 ENOG4105IPS esterase D5G00_06505 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) D5G00_06510 ENOG4105VRH Antibiotic biosynthesis monooxygenase D5G00_06515 ENOG4105NF4 modulator of drug activity D5G00_06520 ENOG4105DHQ Histidine kinase D5G00_06525 ENOG4105XJC Two component transcriptional regulator (Winged helix family D5G00_06530 ENOG4105H4F exported protein D5G00_06535 ENOG4105F4I Transcriptional regulator D5G00_06540 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) D5G00_06545 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase D5G00_06550 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) D5G00_06555 ENOG4105CG6 trap dicarboxylate transporter dctm subunit D5G00_06565 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit D5G00_06570 ENOG4105CCT upf0313 protein D5G00_06585 ENOG4107QPK )-transporter D5G00_06590 ENOG4105CV8 reductase D5G00_06595 ENOG4108I6A alcohol dehydrogenase D5G00_06600 ENOG4105CF7 AraC family transcriptional regulator D5G00_06605 ENOG4108K81 inner membrane protein YghB D5G00_06610 ENOG4105C28 cystathionine D5G00_06620 ENOG4105CWK Biopolymer transport protein, ExbB D5G00_06625 ENOG4108ZZF transport protein (ExbD) D5G00_06630 ENOG4105CYX Short-chain dehydrogenase reductase Sdr D5G00_06660 ENOG4105C8Q Methyl-accepting chemotaxis D5G00_06665 ENOG410900S Protein of unknown function (DUF2623) D5G00_06675 ENOG4105E3S small subunit D5G00_06680 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein D5G00_06685 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit D5G00_06690 ENOG4105DPX Hydrogenase, large subunit D5G00_06695 ENOG4108USZ hydrogenase D5G00_06700 ENOG4108WGS hydrogenase 2-specific chaperone D5G00_06705 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) D5G00_06710 ENOG41082MF Hydrogenase assembly chaperone hypC hupF D5G00_06720 ENOG4108VJC ABC transporter, periplasmic molybdate-binding protein D5G00_06725 ENOG4105CYM Glutathione S-transferase D5G00_06730 ENOG4106032 Glutathionylspermidine synthase D5G00_06750 ENOG4105DEI Mannitol dehydrogenase D5G00_06760 ENOG4105DPW Major facilitator superfamily MFS_1 D5G00_06785 ENOG4105C26 Dehydrogenase D5G00_06790 ENOG4105CJP fad dependent oxidoreductase D5G00_06800 ENOG4105CUB amino acid D5G00_06810 ENOG4108UAJ Transcriptional regulator D5G00_06820 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) D5G00_06830 ENOG4105CI0 Citrate lyase D5G00_06835 ENOG4105DJG MaoC domain protein dehydratase D5G00_06840 ENOG4105CYC Transferase D5G00_06845 ENOG4109025 Glyoxalase Bleomycin resistance protein (Dioxygenase D5G00_06855 ENOG4108UQV Membrane D5G00_06860 ENOG4105CXN decarboxylase D5G00_06865 ENOG4105EAA nucleoside D5G00_06880 ENOG4105CEN a g-specific adenine glycosylase D5G00_06890 ENOG41090ED Protein with unknown function (DUF469) D5G00_06895 ENOG4105K33 Periplasmic Protein D5G00_06900 ENOG4105HDK L-asparaginase D5G00_06905 ENOG4106MH3 alpha helix chain D5G00_06910 ENOG4105CSA Coproporphyrinogen iii oxidase D5G00_06925 ENOG4108VIA integral membrane protein D5G00_06930 ENOG4105DFA alanine racemase domain protein D5G00_06935 ENOG4105CZX twitching motility protein D5G00_06955 ENOG4105D7Z glutathione synthase D5G00_06960 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) D5G00_06965 ENOG4105RWS endonuclease I D5G00_06975 ENOG4107QNK )-transporter D5G00_07000 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) D5G00_07010 ENOG4107YCY Transcriptional regulator D5G00_07020 ENOG4105DEI Mannitol dehydrogenase D5G00_07025 ENOG4105CPQ Dehydrogenase D5G00_07035 ENOG4108R66 Conserved Protein D5G00_07040 ENOG4108MXF Alpha Beta Hydrolase D5G00_07050 ENOG4108K0D peptidase, M48 D5G00_07055 ENOG4105CV1 Transketolase (EC 2.2.1.1) D5G00_07060 ENOG4108JJB ABC transporter D5G00_07065 ENOG4108JJB ABC transporter D5G00_07070 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) D5G00_07100 ENOG4105D2N Aldolase D5G00_07105 ENOG4105D64 Mechanosensitive ion channel D5G00_07115 ENOG4105MPN Membrane D5G00_07135 ENOG4108JQ1 Dehydrogenase D5G00_07140 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase D5G00_07160 ENOG4107RAQ aminopeptidase D5G00_07165 ENOG4105D0A hydroxylase D5G00_07170 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family D5G00_07200 ENOG4105CS2 ec 3.2.1.21 D5G00_07210 ENOG4108UT2 hemolysin iii D5G00_07235 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB D5G00_07240 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) D5G00_07245 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) D5G00_07250 ENOG4105T95 Thiol disulfide interChange protein D5G00_07255 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) D5G00_07265 ENOG4105CRK lysyL-tRNA synthetase D5G00_07280 ENOG4108K5P (LipO)protein D5G00_07300 ENOG4105VGJ Virulence-associated protein D5G00_07305 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A D5G00_07320 ENOG4108T1M outer membrane protein x D5G00_07340 ENOG4106P2F Pfam:Pili_assembly_C D5G00_07370 ENOG4108MHD transport protein D5G00_07380 ENOG4105C5Q Transcriptional regulator D5G00_07385 ENOG4105CHU acetyl-coa acetyltransferase D5G00_07400 ENOG4105CHR reductase D5G00_07405 ENOG4107QNK )-transporter D5G00_07415 ENOG4105RQF LysR family Transcriptional regulator D5G00_07420 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) D5G00_07425 ENOG4105DDV Transcriptional regulator (LacI family D5G00_07455 ENOG4105CPC Aldo Keto reductase D5G00_07460 ENOG4105SUV lipoprotein YgdR D5G00_07465 ENOG4105EE5 Membrane protein terC D5G00_07480 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase D5G00_07500 ENOG4105IPU prepilin peptidase dependent protein A D5G00_07505 ENOG4105JCS prepilin peptidase dependent protein D5G00_07510 ENOG4105SEN Protein of unknown function (DUF2509) D5G00_07515 ENOG4105RVB Prepilin peptidase dependent protein c D5G00_07520 ENOG4105DSY exodeoxyribonuclease V, gamma D5G00_07525 ENOG4107QXK peptidase D5G00_07530 ENOG4107QKA exodeoxyribonuclease V beta D5G00_07535 ENOG4107QYX exodeoxyribonuclease v alpha D5G00_07540 ENOG4108EKC n-acetylglutamate synthase D5G00_07545 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase D5G00_07560 ENOG4105CA3 membrane-bound lytic murein transglycosylase D5G00_07565 ENOG4105CUZ uba thif-type nad fad binding protein D5G00_07570 ENOG4105FR1 rard protein D5G00_07575 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) D5G00_07580 ENOG4105C9B Cysteine desulfurase D5G00_07585 ENOG4105M5B (LipO)protein D5G00_07590 ENOG4105ETT transcriptional Regulator, LysR family D5G00_07595 ENOG4105M08 Membrane D5G00_07605 ENOG4107EDW L-fucose operon activator D5G00_07615 ENOG4105CMG Carbohydrate kinase D5G00_07625 ENOG4105EDR glucose galactose transporter D5G00_07630 ENOG4107W7X Aldolase D5G00_07635 ENOG4105C0A alcohol dehydrogenase D5G00_07650 ENOG4105EJQ L-serine dehydratase D5G00_07655 ENOG4105C44 Serine transporter D5G00_07660 ENOG4105EWT decarboxylase family D5G00_07680 ENOG4105WP7 tRNA pseudouridine synthase C D5G00_07685 ENOG4105DR9 pseudouridine synthase D5G00_07690 ENOG4105QDK Flavodoxin D5G00_07700 ENOG4105DJB Major Facilitator Superfamily D5G00_07710 ENOG4105EQX glucarate dehydratase D5G00_07715 ENOG4105BZW Glycerate kinase D5G00_07720 ENOG4105BZU Histidine kinase D5G00_07725 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) D5G00_07730 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) D5G00_07755 ENOG4105NEV Fimbrial D5G00_07760 ENOG4108FZ9 Chaperone D5G00_07765 ENOG4106PG1 outer membrane usher protein D5G00_07775 ENOG4105DXN mazG family D5G00_07790 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) D5G00_07795 ENOG4108H5C Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) D5G00_07800 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase D5G00_07845 ENOG4105CYR Crispr-associated protein, cse1 family D5G00_07855 ENOG41060M0 Crispr-associated protein, cse4 family D5G00_07860 ENOG4108VWQ crispr-associated protein D5G00_07870 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) D5G00_07875 ENOG4105PWE CRISPR-associated protein cas2 D5G00_07880 ENOG4108MXK alkaline phosphatase isozyme conversion D5G00_07900 ENOG4105N0Z inner membrane protein ygbE D5G00_07945 ENOG4105KZM cytoplasmic protein D5G00_07950 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) D5G00_07955 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase D5G00_07965 ENOG4105MVE transcriptional regulator D5G00_07975 ENOG4105G63 Type III effector Hrp-dependent D5G00_07990 ENOG4105EXW epimerase dehydratase D5G00_07995 ENOG4105C6Z Gluconate D5G00_08000 ENOG4105JQN Transcriptional regulator D5G00_08005 ENOG4105C0R drug resistance transporter emrb qaca subfamily D5G00_08040 ENOG4105MEW serine threonine protein phosphatase D5G00_08070 ENOG41090HZ type iii secretion D5G00_08075 ENOG4105K44 type iii secretion D5G00_08080 ENOG4108N8R Invasion protein D5G00_08085 ENOG4108HR8 type iii secretion D5G00_08090 ENOG4105REY Chaperone specialized in the storage of effectors within the bacterial cytoplasm, maintaining them in a secretion-competent state, and allowing their immediate delivery to target cells upon contact of the bacterium with the host cells. Has been shown to chaperone D5G00_08095 ENOG4108JIR Flagellum-specific ATP synthase D5G00_08100 ENOG41077MC Secretory protein (Associated with virulence) D5G00_08105 ENOG41078G4 surface presentation of D5G00_08115 ENOG41075IY surface presentation of antigens protein SpaP D5G00_08125 ENOG4108TN6 type iii secretion D5G00_08130 ENOG4108M6W surface presentation of antigens protein SpaS D5G00_08150 ENOG4105IBT Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of SipA, SipB, and SipC D5G00_08160 ENOG41079WB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) D5G00_08175 ENOG410641W Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities. After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE. This function is independent of its tyrosine phosphatase activity, which remains unclear D5G00_08185 ENOG4108YAB Invasion protein D5G00_08195 ENOG4108RC9 Type III secretion system protein D5G00_08200 ENOG4105Y7Q type iii secretion D5G00_08205 ENOG4106BTR D5G00_08210 ENOG4108RBT type iii secretion D5G00_08250 ENOG4105CC5 ABC transporter D5G00_08255 ENOG4105CC5 ABC transporter D5G00_08260 ENOG4105DIK (ABC) transporter D5G00_08270 ENOG4105VXR cytoplasmic protein D5G00_08280 ENOG4105C45 hydrogenase expression formation protein (HypE) D5G00_08285 ENOG4105CQS hydrogenase expression formation protein HypD D5G00_08290 ENOG41083WG hydrogenase assembly chaperone D5G00_08295 ENOG4107RSS Hydrogenase accessory protein HypB D5G00_08300 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) D5G00_08310 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA D5G00_08315 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) D5G00_08320 ENOG4107R30 NADH dehydrogenase D5G00_08325 ENOG4107TDF Formate hydrogenlyase subunit 4 D5G00_08330 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) D5G00_08335 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit D5G00_08340 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit D5G00_08345 ENOG4105I6X formate hydrogenlyase maturation D5G00_08350 ENOG4108MG9 hydrogenase 3 maturation protease D5G00_08360 ENOG4108RC0 Electron transport protein D5G00_08365 ENOG4105C8H hydrogenase maturation protein Hypf D5G00_08385 ENOG4105C2X Arabinose 5-phosphate isomerase D5G00_08390 ENOG410804X Transcriptional regulator D5G00_08395 ENOG4105J92 DNA-binding transcriptional activator GutM D5G00_08400 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase D5G00_08405 ENOG4105VI0 Pts system, glucitol sorbitol-specific D5G00_08410 ENOG4105DZY Pts system, glucitol sorbitol-specific D5G00_08415 ENOG410787A Pts system, glucitol sorbitol-specific D5G00_08420 ENOG4105CVE Lytic murein transglycosylase D5G00_08430 ENOG4107TH8 cina domain protein D5G00_08450 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) D5G00_08455 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) D5G00_08490 ENOG4107VXZ Hydrolase D5G00_08495 ENOG4105W39 Membrane D5G00_08515 ENOG4105C0R drug resistance transporter emrb qaca subfamily D5G00_08520 ENOG4105CW7 secretion protein, HlyD family D5G00_08525 ENOG4105NTK Transcriptional repressor Mpra D5G00_08535 ENOG4105GIJ Glycine betaine D5G00_08540 ENOG4108HQS Glycine betaine D5G00_08545 ENOG4108IJ7 Glycine betaine D5G00_08555 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) D5G00_08560 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) D5G00_08570 ENOG4105WAZ (Glutaredoxin-like protein) NrdH D5G00_08580 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) D5G00_08590 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) D5G00_08595 ENOG4108WMJ Protein of unknown function (DUF2002) D5G00_08600 ENOG4108RNS Exports L-alanine (By similarity) D5G00_08610 ENOG4108X73 DNA- binding protein D5G00_08620 ENOG4108V62 Rhodanese domain protein D5G00_08625 ENOG41080HT Transcriptional regulator, arsr family D5G00_08630 ENOG4105VPI YqaE family transport protein D5G00_08640 ENOG4109066 lysm domain bon superfamily protein D5G00_08645 ENOG4108PVQ transcriptional regulator D5G00_08650 ENOG4105C85 amino acid D5G00_08655 ENOG4108JPW Aminotransferase D5G00_08660 ENOG4105C26 Dehydrogenase D5G00_08665 ENOG4105D5U fad dependent oxidoreductase D5G00_08695 ENOG4105DHQ Histidine kinase D5G00_08715 ENOG4108MJ5 VirK protein D5G00_08720 ENOG4105VRE Pentapeptide repeat protein D5G00_08735 ENOG4107RNH Outer membrane receptor FepA D5G00_08740 ENOG4105NIV Esterase D5G00_08805 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) D5G00_08845 ENOG4105KSC Transcriptional regulator, TraR DksA family D5G00_08850 ENOG4105DFE Dna adenine methylase D5G00_08855 ENOG4105VZ1 Replication Protein D5G00_08890 ENOG4105ED4 portal protein D5G00_09030 ENOG4105ZTC transcriptional activator, Ogr delta D5G00_09065 ENOG4108Z1B Cyclase dehydrase D5G00_09075 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) D5G00_09080 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) D5G00_09105 ENOG4108JU6 CBS domain protein D5G00_09110 ENOG4106KVJ cytochrome C assembly protein D5G00_09120 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY D5G00_09145 ENOG4108KHX Diguanylate cyclase D5G00_09150 ENOG4108WS1 D5G00_09155 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) D5G00_09160 ENOG4105EHE chorismate mutase- prephenate dehydrogenase D5G00_09170 ENOG4105CQC Prephenate dehydratase D5G00_09180 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA D5G00_09185 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane D5G00_09190 ENOG4105C34 Pseudouridine synthase D5G00_09195 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase D5G00_09200 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit D5G00_09230 ENOG4105CSH Transporter D5G00_09235 ENOG4105T42 (LipO)protein D5G00_09240 ENOG4105JIM Phosphatidylserine synthase D5G00_09245 ENOG4105CD5 CoA-binding domain protein D5G00_09250 ENOG4106IUH DTW domain containing protein D5G00_09255 ENOG4105K63 Thioredoxin D5G00_09260 ENOG4105EIB trna rrna methyltransferase D5G00_09280 ENOG41090KR LysR family transcriptional Regulator D5G00_09285 ENOG4105C1J atp-dependent rna helicase D5G00_09295 ENOG4108IYU L-aspartate oxidase D5G00_09320 ENOG4105WMJ Positive regulator of sigma E, RseC MucC D5G00_09335 ENOG4105C3F Signal peptidase i D5G00_09360 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) D5G00_09370 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding D5G00_09375 ENOG4105DND Transcriptional regulator D5G00_09380 ENOG4105FCD Major Facilitator D5G00_09390 ENOG4106G6Q Transcriptional regulator D5G00_09405 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB D5G00_09410 ENOG4108Z6B deaminase D5G00_09415 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) D5G00_09425 ENOG4108ETH Formylglycinamide ribotide synthetase D5G00_09430 ENOG4107WP9 Histidine kinase D5G00_09435 ENOG4108SKK alpha helix protein D5G00_09440 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family D5G00_09445 ENOG4108YZA Nitrogen regulatory protein pii D5G00_09450 ENOG4105DUX Transporter D5G00_09455 ENOG4105CXN decarboxylase D5G00_09460 ENOG4105D5Q Arginine ornithine antiporter D5G00_09465 ENOG4108M3R transcriptional activator CadC D5G00_09470 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) D5G00_09475 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) D5G00_09480 ENOG4105D8G Major Facilitator superfamily D5G00_09485 ENOG4108MN2 Stationary phase inducible protein CsiE D5G00_09495 ENOG4105D7X high-affinity nickel-transporter D5G00_09500 ENOG410810Y Sulfite reductase D5G00_09505 ENOG4107SHJ sulfite reductase subunit b D5G00_09510 ENOG4105D5B Sulfite reductase, subunit A D5G00_09515 ENOG4107XM9 (LipO)protein D5G00_09520 ENOG4105ECY inositol monophosphatase D5G00_09540 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins D5G00_09560 ENOG4108ZIT Ferredoxin, 2FE-2S D5G00_09565 ENOG4105WVQ Fe-S assembly protein IscX D5G00_09575 ENOG4105YYA enhanced serine sensitivity protein SseB D5G00_09595 ENOG4105KHC sulfurtransferase D5G00_09605 ENOG4108JQB penicillin-binding protein 1C D5G00_09610 ENOG4107QY8 reductase D5G00_09615 ENOG4105QAX Iron-sulfur D5G00_09660 ENOG4105N21 Membrane D5G00_09665 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) D5G00_09675 ENOG4105VPD cellular component movement D5G00_09715 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) D5G00_09740 ENOG41062G3 Protein of unknown function (DUF2633) D5G00_09750 ENOG4105BZU Histidine kinase D5G00_09755 ENOG4105C9X ppx gppa phosphatase D5G00_09760 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) D5G00_09765 ENOG4108V3E phosphoribosylglycinamide formyltransferase D5G00_09785 ENOG4105C2W permease D5G00_09795 ENOG4105K89 arsenate reductase D5G00_09800 ENOG4105ERG peptidase m48, ste24p D5G00_09805 ENOG4105C02 permease D5G00_09810 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR D5G00_09815 ENOG4107QQ0 gntp family D5G00_09820 ENOG4105BZW Glycerate kinase D5G00_09825 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen D5G00_09830 ENOG4105RH4 Glycine cleavage system transcriptional repressor D5G00_09835 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) D5G00_09840 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) D5G00_09850 ENOG4105CGZ zinc metallopeptidase D5G00_09855 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) D5G00_09865 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) D5G00_09870 ENOG4105KUZ arsenate reductase D5G00_09880 ENOG4105BZS acriflavin resistance protein D5G00_09885 ENOG4105BZU Histidine kinase D5G00_09895 ENOG4105BZ8 glutamate synthase D5G00_09910 ENOG4107VIJ nudix hydrolase D5G00_09915 ENOG4108PVD exported protein D5G00_09925 ENOG4105CV1 Transketolase (EC 2.2.1.1) D5G00_09930 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) D5G00_09940 ENOG4105C6K Malic enzyme D5G00_09945 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place D5G00_09950 ENOG4106S4J ethanolamine utilization protein EutP D5G00_09955 ENOG4105NDK ethanolamine utilization protein D5G00_09960 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase D5G00_09965 ENOG4108IJ2 phosphate acetyltransferase D5G00_09970 ENOG4105KNY Microcompartments protein D5G00_09975 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml D5G00_09980 ENOG4108EKI Dehydrogenase D5G00_09985 ENOG4107RWI ethanolamine utilization protein eutJ D5G00_09990 ENOG4105C0A alcohol dehydrogenase D5G00_09995 ENOG4105ENY Ethanolamine utilization protein eutH D5G00_10000 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase D5G00_10005 ENOG4105CPD ethanolamine ammonia-lyase D5G00_10015 ENOG4106D67 ethanolamine utilization protein D5G00_10020 ENOG4108X49 Ethanolamine utilization protein EutK D5G00_10025 ENOG4108K3Z AraC family transcriptional regulator D5G00_10045 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase D5G00_10055 ENOG4105QZU Inner membrane protein YfeZ D5G00_10060 ENOG4105E7K (LipO)protein D5G00_10065 ENOG4105EZR dyp-type peroxidase family protein D5G00_10070 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr D5G00_10075 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein D5G00_10080 ENOG4108I5D sulfate abc transporter D5G00_10085 ENOG4105ECW sulfate abc transporter D5G00_10090 ENOG4108IJ6 ABC transporter D5G00_10095 ENOG4105C6T cysteine synthase D5G00_10110 ENOG4105M0Y D5G00_10115 ENOG41089BK Glutamine amido-transferase D5G00_10120 ENOG4105CSW GntR family transcriptional regulator D5G00_10135 ENOG4105C5Y PTS System D5G00_10145 ENOG4105KZ7 phosphocarrier protein hpr D5G00_10150 ENOG4105C6T cysteine synthase D5G00_10170 ENOG4105VRT cytoplasmic protein D5G00_10175 ENOG4105DHU Bile acid D5G00_10180 ENOG4108M0I Transcriptional regulator D5G00_10185 ENOG4108NFH Sugar hydrolase D5G00_10190 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) D5G00_10195 ENOG4105EAA nucleoside D5G00_10205 ENOG4105CN8 Transcriptional regulator D5G00_10235 ENOG4105GXM Putative transcription regulator (DUF1323) D5G00_10240 ENOG4105HZG regulatoR D5G00_10260 ENOG4108KMM Diguanylate cyclase D5G00_10265 ENOG4105D9N nucleoside D5G00_10275 ENOG4109076 Conserved Protein D5G00_10280 ENOG4105CPC Aldo Keto reductase D5G00_10300 ENOG4105CHM Aminotransferase D5G00_10310 ENOG4105D1S lipid A biosynthesis D5G00_10315 ENOG4105W9M Membrane D5G00_10320 ENOG4105CXY transporter D5G00_10340 ENOG4107TXD phosphoglycerate transport system transcriptional regulatory protein pgta D5G00_10345 ENOG4108NC2 Outer membrane protease D5G00_10365 ENOG4105EXC Acyl-transferase D5G00_10370 ENOG4105CKK Glycosyl transferase, family 2 D5G00_10375 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) D5G00_10395 ENOG4105S64 Formate nitrite transporter D5G00_10400 ENOG410903C (LipO)protein D5G00_10405 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation D5G00_10410 ENOG4105KZW UPF0381 protein D5G00_10425 ENOG4108BY2 phosphohistidine phosphatase D5G00_10435 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) D5G00_10450 ENOG4105EJ9 Membrane D5G00_10455 ENOG4108BPE -transporting atpase D5G00_10460 ENOG4105MH2 YfcL protein D5G00_10465 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) D5G00_10470 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) D5G00_10505 ENOG4106WZ1 flagella biosynthesis regulator D5G00_10515 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) D5G00_10525 ENOG4105DQR SNARE associated Golgi D5G00_10535 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase D5G00_10540 ENOG4108S3P Sporulation domain protein D5G00_10545 ENOG4105E96 Colicin v production protein D5G00_10550 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase D5G00_10555 ENOG4108JUB Transcriptional regulator D5G00_10565 ENOG4105E5D amino acid D5G00_10570 ENOG4106M28 alanine racemase domain protein D5G00_10575 ENOG4108IQI permease D5G00_10580 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase D5G00_10590 ENOG4105E89 ABC transporter D5G00_10595 ENOG4105E89 ABC transporter D5G00_10600 ENOG4105DSP amino acid AbC transporter D5G00_10605 ENOG4106YG3 ABC transporter D5G00_10610 ENOG4108JEH abc transporter atp-binding protein D5G00_10615 ENOG4105ECP epimerase D5G00_10620 ENOG4105CYM Glutathione S-transferase D5G00_10625 ENOG4108SHQ Glutathione S-transferase D5G00_10630 ENOG4108RE9 Phosphodiesterase D5G00_10635 ENOG4105PTV Nudix Hydrolase D5G00_10640 ENOG4105K2J Transcriptional regulator D5G00_10650 ENOG4106ETB IIa component D5G00_10660 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC D5G00_10665 ENOG4108HHA Transketolase D5G00_10670 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) D5G00_10675 ENOG4105CSX c4-dicarboxylate anaerobic carrier D5G00_10680 ENOG4105C6K Malic enzyme D5G00_10685 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) D5G00_10700 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 D5G00_10705 ENOG4107QWE )-transporter D5G00_10720 ENOG4105CHM Aminotransferase D5G00_10730 ENOG4107NQ8 LysR family Transcriptional regulator D5G00_10755 ENOG4105GKE subunit e D5G00_10760 ENOG4107QIZ NADH dehydrogenase D5G00_10765 ENOG4107R0R NADH dehydrogenase subunit g D5G00_10780 ENOG4107UFS subunit j D5G00_10790 ENOG4105D65 subunit l D5G00_10800 ENOG4105C8S subunit m D5G00_10815 ENOG4105CP2 von willebrand factor, type a D5G00_10820 ENOG4107R88 Chemotaxis protein (CheV) D5G00_10830 ENOG4107YB6 acetyltransferase, (GNAT) family D5G00_10835 ENOG4105TNS Conserved Protein D5G00_10840 ENOG4105E4F Isochorismate synthase D5G00_10855 ENOG4108IPT Naphthoate synthase D5G00_10865 ENOG4105CEY Amp-dependent synthetase and ligase D5G00_10870 ENOG4106GZG polymyxin resistance protein B D5G00_10905 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase D5G00_10920 ENOG4108UII YfaZ family D5G00_10930 ENOG4107258 Transcriptional regulator D5G00_10940 ENOG4105CSP Major Facilitator Superfamily D5G00_10965 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) D5G00_10975 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A D5G00_10980 ENOG4105CXY transporter D5G00_10985 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase D5G00_10990 ENOG4105GZI Transcriptional regulator D5G00_10995 ENOG4105CZM Major Facilitator D5G00_11000 ENOG4105XPH Ferredoxin D5G00_11005 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) D5G00_11010 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) D5G00_11030 ENOG4105CXK mandelate racemase muconate lactonizing D5G00_11040 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) D5G00_11045 ENOG4105BZU Histidine kinase D5G00_11050 ENOG41068CG regulatoR D5G00_11055 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC D5G00_11060 ENOG4105FCK Membrane D5G00_11065 ENOG4105CJ2 (LipO)protein D5G00_11070 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) D5G00_11075 ENOG4105CF1 Alkylated DNA repair protein D5G00_11080 ENOG4105IBP Cyclic peptide transporter D5G00_11090 ENOG4108ZNS ferredoxin-type protein NapF D5G00_11095 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase D5G00_11105 ENOG4108BGM Quinol dehydrogenase periplasmic component D5G00_11110 ENOG4105GXZ Ferredoxin-type protein NapH D5G00_11120 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) D5G00_11125 ENOG4105CUW cytochrome C-TYPE protein D5G00_11130 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) D5G00_11135 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) D5G00_11140 ENOG41060IM Heme exporter protein D5G00_11145 ENOG4105X3C heme exporter protein D5G00_11150 ENOG4108ZKK Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity) D5G00_11155 ENOG4105DA4 cytochrome c-type biogenesis protein D5G00_11160 ENOG4107QX9 Thiol disulfide interChange protein D5G00_11165 ENOG4105KWW Biogenesis protein D5G00_11170 ENOG4105WH1 Two component transcriptional regulator luxr family D5G00_11220 ENOG4105E68 Sulfatase D5G00_11245 ENOG4105CFI type iii restriction protein res subunit D5G00_11250 ENOG4105I08 Pseudouridine synthase D5G00_11255 ENOG4105C2C drug resistance transporter, Bcr CflA D5G00_11260 ENOG4105HG6 D5G00_11265 ENOG4108JQ5 ABC transporter D5G00_11270 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component D5G00_11275 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component D5G00_11280 ENOG4105E43 Extracellular solute-binding protein, family 5 D5G00_11285 ENOG4105CXC rtn protein D5G00_11290 ENOG4107TT5 NLP P60 protein D5G00_11300 ENOG41076MN Phosphoesterase, PA-phosphatase related D5G00_11305 ENOG4105CKI cobalamin synthesis protein D5G00_11310 ENOG4105FUQ Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) D5G00_11320 ENOG4105KRS Proteinase inhibitor D5G00_11335 ENOG4105S8Q sugar efflux transporter D5G00_11340 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein D5G00_11345 ENOG4105DE4 1-phosphofructokinase D5G00_11350 ENOG4105DM4 PTS System D5G00_11360 ENOG4105HMI Membrane D5G00_11365 ENOG4105DUM transcriptional regulator, lysR family D5G00_11370 ENOG4108IQI permease D5G00_11380 ENOG4105D05 Receptor D5G00_11385 ENOG4105CXY transporter D5G00_11390 ENOG4105EAC phosphoserine phosphatase D5G00_11395 ENOG4105EJQ L-serine dehydratase D5G00_11420 ENOG4105DHF Membrane D5G00_11425 ENOG41060NJ transcriptional regulator D5G00_11440 ENOG4107SDZ Galactoside transport system permease protein mglC D5G00_11445 ENOG4107SJI Dehydrogenase D5G00_11450 ENOG4105BZ8 glutamate synthase D5G00_11455 ENOG4105Y9N Membrane D5G00_11460 ENOG4107GZ4 SanA protein D5G00_11470 ENOG41067MG lrgb family D5G00_11500 ENOG4108RXX maleylacetoacetate isomerase D5G00_11505 ENOG4105MSY salicylate hydroxylase D5G00_11520 ENOG4105ETP RND efflux system, outer membrane lipoprotein D5G00_11525 ENOG4105H9W Short-chain dehydrogenase reductase Sdr D5G00_11530 ENOG4105KHU inner membrane protein YohD D5G00_11535 ENOG41069YE inner membrane protein yohC D5G00_11545 ENOG41061WM D-Alanyl-D-Alanine D5G00_11550 ENOG4105CXG d-lactate dehydrogenase D5G00_11555 ENOG4107QK4 glycoside hydrolase, family 3 domain protein D5G00_11560 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system D5G00_11565 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component D5G00_11570 ENOG4108IJ8 ABC transporter D5G00_11575 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component D5G00_11590 ENOG4108HRK Histidine kinase D5G00_11595 ENOG4108NEV two component transcriptional regulator, LytTR family D5G00_11600 ENOG4108W15 Protein of unknown function (DUF1456) D5G00_11610 ENOG4108YCW (LipO)protein D5G00_11620 ENOG4105D1F ATP-binding protein D5G00_11640 ENOG4105CW0 outer membrane usher protein D5G00_11645 ENOG410662B Type-1 fimbrial protein D5G00_11650 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly D5G00_11660 ENOG4105DWF phosphomethylpyrimidine kinase D5G00_11665 ENOG4105FDP GntR family transcriptional regulator D5G00_11670 ENOG4108TFM Kinase, PfkB family D5G00_11675 ENOG4108KD5 ADP-ribosylation crystallin J1 D5G00_11680 ENOG4105EAA nucleoside D5G00_11685 ENOG4105EIE fructose-bisphosphate aldolase D5G00_11700 ENOG41090V3 Tir chaperone protein (CesT) family D5G00_11710 ENOG4105CFP Peptidase U32 D5G00_11735 ENOG4105E3W Two component transcriptional regulator (Winged helix family D5G00_11740 ENOG4105EB3 Histidine kinase D5G00_11750 ENOG4105BZS acriflavin resistance protein D5G00_11780 ENOG4105D03 DNA-3-methyladenine glycosylase II D5G00_11800 ENOG4108GAE asmA family D5G00_11805 ENOG4105EE5 Membrane protein terC D5G00_11815 ENOG4105DAY polysaccharide export protein D5G00_11820 ENOG4105KJF protein tyrosine phosphatase D5G00_11825 ENOG4105D75 Capsular exopolysaccharide family D5G00_11830 ENOG41090RK glycosyl transferase D5G00_11835 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB D5G00_11840 ENOG4107RXY Glycosyl transferase D5G00_11845 ENOG4108NYJ Colanic acid D5G00_11850 ENOG4105ECJ Glycosyl Transferase D5G00_11855 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF D5G00_11860 ENOG4105C0K Gdp-mannose 4,6-dehydratase D5G00_11865 ENOG4105C30 Nad-dependent epimerase dehydratase D5G00_11870 ENOG4105FGF GDP-mannose mannosyl hydrolase D5G00_11875 ENOG4106CD9 glycosyl transferase group 1 D5G00_11880 ENOG4105CJT Mannose-1-phosphate guanylyltransferase D5G00_11885 ENOG4107QKV phosphomannomutase D5G00_11890 ENOG4105D3Q Sugar transferase D5G00_11895 ENOG4105PSV Polysaccharide Biosynthesis Protein D5G00_11900 ENOG4105C74 pyruvyl transferase D5G00_11905 ENOG4107T8Q Glycosyl transferase (Group 1 D5G00_11910 ENOG4105G1A colanic acid biosynthesis protein D5G00_11915 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase D5G00_11920 ENOG4105C1B dTDP-glucose 4-6-dehydratase D5G00_11925 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase D5G00_11930 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) D5G00_11935 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase D5G00_11940 ENOG4107QK7 reductase D5G00_11945 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase D5G00_11950 ENOG4105FAW cDP-glucose 4,6-dehydratase D5G00_11955 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase D5G00_11960 ENOG4108SMP Nad-dependent epimerase dehydratase D5G00_11965 ENOG4108IAJ Nad-dependent epimerase dehydratase D5G00_11970 ENOG41081E6 Inherit from COG: Polysaccharide biosynthesis protein D5G00_11975 ENOG4107YYJ Glycosyl transferase, family 2 D5G00_11980 ENOG4108TJN glycosyl transferase group 1 D5G00_11985 ENOG4108KBE Glycosyl transferase, family 2 D5G00_11990 ENOG4105CJT Mannose-1-phosphate guanylyltransferase D5G00_11995 ENOG4106ECQ phosphomannomutase D5G00_12000 ENOG4105D3Q Sugar transferase D5G00_12005 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) D5G00_12015 ENOG4105C6Y Udp-glucose 6-dehydrogenase D5G00_12020 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) D5G00_12025 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase D5G00_12055 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) D5G00_12070 ENOG4108535 NAD dependent epimerase/dehydratase family D5G00_12075 ENOG4105EQ1 Transcriptional regulator D5G00_12085 ENOG4105CUB amino acid D5G00_12090 ENOG4105CJB Exodeoxyribonuclease I D5G00_12110 ENOG4108J2R molybdopterin oxidoreductase D5G00_12115 ENOG4105QAX Iron-sulfur D5G00_12120 ENOG4108NWD Cytochrome D5G00_12125 ENOG4105DZ1 carboxypeptidase D5G00_12130 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) D5G00_12135 ENOG4105DR8 Membrane D5G00_12145 ENOG4105JZC GHMP kinase D5G00_12150 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) D5G00_12155 ENOG4105KTW ethanolamine utilization protein D5G00_12160 ENOG4105M3W utilization protein D5G00_12170 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) D5G00_12175 ENOG4108EKI Dehydrogenase D5G00_12180 ENOG4108EKI Dehydrogenase D5G00_12190 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml D5G00_12200 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) D5G00_12205 ENOG4105S3V Carbon dioxide concentrating mechanism protein D5G00_12210 ENOG4105KNY Microcompartments protein D5G00_12220 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit D5G00_12225 ENOG4108ZFT Dehydratase small subunit D5G00_12230 ENOG4105YCI dehydratase medium subunit D5G00_12235 ENOG4105DMB glycerol dehydratase D5G00_12240 ENOG4105EHR propanediol utilization protein pduB D5G00_12245 ENOG4105KNY Microcompartments protein D5G00_12250 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) D5G00_12260 ENOG4105C0Y Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) D5G00_12270 ENOG41081F0 Precorrin-8x methylmutase D5G00_12280 ENOG4108DR9 Cobalt-precorrin-6Y C(5)-methyltransferase D5G00_12285 ENOG4107XSI cobalt-precorrin-6y C15-methyltransferase D5G00_12290 ENOG4105CIA precorrin-4 C(11)-methyltransferase D5G00_12295 ENOG4108P62 biosynthesis protein (CbiG) D5G00_12300 ENOG4105E4R Precorrin-3B C17-methyltransferase D5G00_12305 ENOG4105QUC reductase D5G00_12310 ENOG4107PPM cobalt chelatase D5G00_12315 ENOG4105DVK Precorrin-2 c20-methyltransferase D5G00_12320 ENOG4105CFT Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) D5G00_12330 ENOG4108V4M Cobalt abc transporter D5G00_12335 ENOG4108JJB ABC transporter D5G00_12345 ENOG4108YZT Adenosylcobinamide kinase D5G00_12360 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein D5G00_12370 ENOG4105UQX Mate efflux family protein D5G00_12400 ENOG4105FYV Amp nucleosidase D5G00_12470 ENOG4108YX2 DNA-binding protein D5G00_12640 ENOG4108R7K Metal Dependent Phosphohydrolase D5G00_12645 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) D5G00_12650 ENOG4105H40 D5G00_12670 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) D5G00_12690 ENOG4108S1U D5G00_12695 ENOG4106050 phage regulatory protein, rha family D5G00_12715 ENOG4105DFE Dna adenine methylase D5G00_12720 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) D5G00_12730 ENOG4108MXB Protein of unknown function (DUF968) D5G00_12735 ENOG4105HGD Antitermination protein D5G00_12785 ENOG4105CAR Terminase, large subunit D5G00_12840 ENOG4105TKZ Tail Sheath D5G00_12880 ENOG4108T86 baseplate J family protein D5G00_12885 ENOG4105Y0G tail protein D5G00_12890 ENOG4105Y9F tail fiber protein D5G00_12895 ENOG4105UZW Tail fiber assembly protein D5G00_12905 ENOG4108C33 Resolvase D5G00_12930 ENOG4105EQR Transposase IS116 IS110 IS902 D5G00_12995 ENOG4107XHZ cytoplasmic chaperone TorD family protein D5G00_13000 ENOG4108UQ5 membrane protein YcdZ D5G00_13005 ENOG4105P8Q Curli production assembly transport component CsgG D5G00_13010 ENOG4108WYR Curli production assembly transport component, CsgF D5G00_13015 ENOG4108XDW curli assembly protein CsgE D5G00_13020 ENOG41086KC Transcriptional regulator D5G00_13050 ENOG4108UVJ appr-1-p processing domain protein D5G00_13055 ENOG4107RZC phospholipase d D5G00_13070 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) D5G00_13075 ENOG4105NAC (LipO)protein D5G00_13080 ENOG4108W47 Acidic protein msyB D5G00_13095 ENOG4105D1S lipid A biosynthesis D5G00_13105 ENOG4108YYC ycei family D5G00_13110 ENOG4105DS1 cytochrome b561 D5G00_13120 ENOG4106974 biofilm formation D5G00_13130 ENOG4105PVA Biofilm formation regulatory protein BssS D5G00_13135 ENOG4105MEA DNA damage-inducible protein i D5G00_13145 ENOG4105F3T (LipO)protein D5G00_13150 ENOG4105E9S glutaredoxin 2 D5G00_13160 ENOG4105D9U N-acetyltransferase D5G00_13170 ENOG4105EP9 oxidoreductase D5G00_13175 ENOG4105CJR Integral membrane protein (MviN D5G00_13180 ENOG4105QVD Flagella synthesis protein FlgN D5G00_13185 ENOG4105M9M anti-sigma28 factor FlgM D5G00_13190 ENOG4105CKS Flagella basal body P-ring formation protein flgA D5G00_13200 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) D5G00_13205 ENOG4108ZC9 flagellar basal-body rod protein flgc D5G00_13210 ENOG4105W00 Flagellar hook capping protein D5G00_13215 ENOG4105BZE flagellar hook protein, FlgE D5G00_13220 ENOG4108KPB Flagellar basal-body rod protein FlgF D5G00_13225 ENOG4105CGA flagellar basal-body rod protein FlgG D5G00_13240 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj D5G00_13245 ENOG4105E1Q flagellar hook-associated protein D5G00_13250 ENOG4105DTJ flagellar hook-associated protein D5G00_13260 ENOG4107QQB Ribonuclease E D5G00_13265 ENOG41071G1 Uncharacterized protein YceQ D5G00_13270 ENOG4105EI2 Pseudouridine synthase D5G00_13285 ENOG4108UHJ MAF-like protein D5G00_13290 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein D5G00_13310 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase D5G00_13315 ENOG4105CHR reductase D5G00_13320 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) D5G00_13325 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) D5G00_13330 ENOG4105YAZ 4-amino-4-deoxychorismate lyase D5G00_13335 ENOG4105HHA aminodeoxychorismate lyase D5G00_13345 ENOG4107QRG dna polymerase iii D5G00_13350 ENOG4105F8V Hydrolase, tatD family D5G00_13355 ENOG4105CI1 PTS System D5G00_13360 ENOG4105CNM Receptor D5G00_13365 ENOG4105K59 histidine triad (HIT) protein D5G00_13370 ENOG41090DQ Lipoprotein D5G00_13375 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) D5G00_13395 ENOG4105CEP NADH dehydrogenase D5G00_13400 ENOG4107MBR 17 kDa surface antigen D5G00_13405 ENOG4108IND Tetr family transcriptional regulator D5G00_13410 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction D5G00_13420 ENOG4108JA2 transcriptioN-repair coupling factor D5G00_13425 ENOG4105D60 lipoprotein releasing system transmembrane protein D5G00_13435 ENOG4105D60 lipoprotein releasing system transmembrane protein D5G00_13445 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) D5G00_13450 ENOG4107RUE extracellular solute-binding protein family 1 D5G00_13455 ENOG4105D38 putrescine abc transporter D5G00_13465 ENOG4105F38 ABC transporter, permease D5G00_13485 ENOG4105EZE Cupin 4 family protein D5G00_13500 ENOG4107QTF adenylosuccinate lyase D5G00_13525 ENOG4108R99 pseudouridine synthase D5G00_13530 ENOG4108HMX isocitrate dehydrogenase (NADP) D5G00_13555 ENOG4105Y50 Virulence Protein D5G00_13560 ENOG4106F2Y RICIN D5G00_13565 ENOG41060EU Cold shock-like protein D5G00_13580 ENOG4105H38 Membrane D5G00_13605 ENOG4108ZNX Heat shock protein D5G00_13615 ENOG4108VKM cytochrome b561 D5G00_13630 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component D5G00_13640 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) D5G00_13645 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) D5G00_13650 ENOG4105D64 Mechanosensitive ion channel D5G00_13665 ENOG4108MEK Metal-binding protein YodA D5G00_13680 ENOG4108Z6Z Transcriptional regulator D5G00_13695 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) D5G00_13710 ENOG4108YS1 cytoplasmic protein D5G00_13715 ENOG4105YP6 Domain of unknown function (DUF1869) D5G00_13730 ENOG4105Y3U Transglycosylase-associated protein D5G00_13735 ENOG4106G4W D5G00_13740 ENOG4105UCG Domain of unknown function (DUF333) D5G00_13750 ENOG4105K78 MarR family Transcriptional regulator D5G00_13755 ENOG4105DJ2 Major Facilitator Superfamily D5G00_13760 ENOG4105R1U AraC Family Transcriptional Regulator D5G00_13775 ENOG4108KXH Ybak prolyl-tRNA synthetase associated D5G00_13780 ENOG4108KHP Diguanylate cyclase D5G00_13795 ENOG4105CYN Serine protein kinase D5G00_13800 ENOG4105GNX MltA-interacting MipA family protein D5G00_13805 ENOG4105C4X radical SAM domain protein D5G00_13810 ENOG4105CV8 reductase D5G00_13815 ENOG4105DSB aldose 1-epimerase D5G00_13825 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase D5G00_13835 ENOG4105VUT cytoplasmic protein D5G00_13845 ENOG4105CPQ Dehydrogenase D5G00_13850 ENOG4107TE1 transport protein D5G00_13855 ENOG4105CPQ Dehydrogenase D5G00_13860 ENOG4105D2N Aldolase D5G00_13865 ENOG4107UH8 sugar kinase D5G00_13870 ENOG4105CPC Aldo Keto reductase D5G00_13875 ENOG4105E98 transcriptional regulator DeoR family D5G00_13880 ENOG4108KUU Inner membrane metabolite transport protein ydjE D5G00_13885 ENOG4108RWI nicotinamidase D5G00_13890 ENOG4105HDK L-asparaginase D5G00_13895 ENOG4105D07 Signal peptide peptidase, SppA D5G00_13900 ENOG41069NU Nitroreductase D5G00_13905 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) D5G00_13910 ENOG4108IYH Dna topoisomerase D5G00_13915 ENOG4105D82 Glutamate dehydrogenase D5G00_13920 ENOG4105MTM Protein of unknown function (DUF1496) D5G00_13925 ENOG4105M6F mutator MutT protein D5G00_13930 ENOG4105CGK Exodeoxyribonuclease III D5G00_13970 ENOG4108SPG Periplasmic Protein D5G00_13975 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) D5G00_13985 ENOG4105KKI DNA-binding transcriptional activator OsmE D5G00_13995 ENOG4105VZJ PTS System D5G00_14000 ENOG4105CK1 PTS System D5G00_14005 ENOG4105VCP PTS System D5G00_14010 ENOG4105EZV Transcriptional regulator D5G00_14015 ENOG4105F8D glycoside hydrolase family 4 D5G00_14025 ENOG4105CH6 catalase D5G00_14040 ENOG4108ETY sodium dicarboxylate symporter D5G00_14045 ENOG4107K5X Membrane-bound metal-dependent hydrolase D5G00_14050 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 D5G00_14055 ENOG4107PN8 YfeABCD locus regulator D5G00_14060 ENOG4105FGM Fructosamine kinase D5G00_14065 ENOG4105P10 Uncharacterized protein ydiZ D5G00_14070 ENOG4105DE4 1-phosphofructokinase D5G00_14075 ENOG4108NE3 Salt-induced outer membrane protein D5G00_14100 ENOG4105K25 O-Antigen polymerase D5G00_14115 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) D5G00_14120 ENOG41082NX 50s ribosomal protein l35 D5G00_14125 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) D5G00_14140 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) D5G00_14145 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) D5G00_14155 ENOG4108V06 Glutathione peroxidase D5G00_14165 ENOG4108QBX (LipO)protein D5G00_14180 ENOG4106EDX Hemin uptake protein D5G00_14185 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) D5G00_14195 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) D5G00_14200 ENOG4105CEY Amp-dependent synthetase and ligase D5G00_14205 ENOG41090P5 ferredoxin-like protein D5G00_14210 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase D5G00_14215 ENOG4105C10 Electron transfer flavoprotein D5G00_14220 ENOG4105CV7 Electron transfer flavoprotein D5G00_14230 ENOG4105C1G acyl-Coa dehydrogenase D5G00_14235 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) D5G00_14250 ENOG4105EMV Major Facilitator D5G00_14255 ENOG4105EMV Major Facilitator D5G00_14260 ENOG4105SUA Ydil protein D5G00_14270 ENOG4105IPI Membrane D5G00_14275 ENOG4105CQB FAD linked oxidase domain protein D5G00_14280 ENOG4105KA0 thioesterase Superfamily protein D5G00_14285 ENOG410671Z uncharacterized protein ydiH D5G00_14290 ENOG4108ETY sodium dicarboxylate symporter D5G00_14295 ENOG4108Z4V iron-sulfur cluster assembly D5G00_14300 ENOG4105DIW FeS assembly protein SUFB D5G00_14305 ENOG4105C3K feS assembly ATPase SufC D5G00_14310 ENOG4105JRK feS assembly protein SufD D5G00_14325 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein D5G00_14340 ENOG4105CA9 Pyruvate kinase D5G00_14350 ENOG4105CUB amino acid D5G00_14355 ENOG4107RCM Releases the N-terminal proline from various substrates (By similarity) D5G00_14365 ENOG4108RVA ribokinase D5G00_14370 ENOG4105DB1 molybdopterin oxidoreductase D5G00_14375 ENOG4106WHD Tetrathionate reductase D5G00_14380 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein D5G00_14385 ENOG4106AFQ Histidine kinase D5G00_14390 ENOG4108ZXC Two component transcriptional regulator, luxr family D5G00_14395 ENOG4105RFR Protein of unknown function (DUF2767) D5G00_14400 ENOG4107SEY Conserved Protein D5G00_14415 ENOG4105BZU Histidine kinase D5G00_14445 ENOG4105ZQI secreted protein D5G00_14455 ENOG4108SZ7 secretion system effector D5G00_14460 ENOG4106FZW pathogenicity island effector protein D5G00_14510 ENOG4106563 type III secretion system apparatus protein D5G00_14515 ENOG4105UQF type iii secretion D5G00_14520 ENOG4106H1D secretion system apparatus protein D5G00_14530 ENOG4108JIR Flagellum-specific ATP synthase D5G00_14545 ENOG41063Q7 Type III secretion system protein D5G00_14550 ENOG4108HHI Type III secretion system protein D5G00_14555 ENOG41083GP type iii secretion D5G00_14560 ENOG4108TN6 type iii secretion D5G00_14565 ENOG4108IUF type iii secretion D5G00_14585 ENOG4108R6K riboflavin synthase, subunit alpha D5G00_14590 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase D5G00_14595 ENOG4105CZQ inner membrane transport protein YdhC D5G00_14600 ENOG4105F52 Transcriptional regulator D5G00_14615 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) D5G00_14620 ENOG4105K4H Nlp p60 protein D5G00_14625 ENOG4105M2J Glutaredoxin D5G00_14640 ENOG4108UYE Lactoylglutathione lyase D5G00_14645 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase D5G00_14650 ENOG4108WUH Transcriptional regulator, TetR family D5G00_14655 ENOG4105XZD Fe-S protein D5G00_14660 ENOG4107RGM aldo keto reductase D5G00_14665 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) D5G00_14670 ENOG4105DSW Fusaric acid resistance protein D5G00_14675 ENOG4105Y49 secretion protein, HlyD family D5G00_14690 ENOG4108XTF Outer Membrane Lipoprotein D5G00_14700 ENOG410642K Lysozyme inhibitor D5G00_14720 ENOG4108K3A Glutathione S-transferase D5G00_14725 ENOG4105DUX Transporter D5G00_14730 ENOG4105CSM endonuclease III D5G00_14740 ENOG4108UQQ Electron transport complex D5G00_14765 ENOG4105M9B inner membrane protein ydgK D5G00_14775 ENOG4106C6R beta-lactam resistance protein D5G00_14780 ENOG4105D9R oxidoreductase D5G00_14795 ENOG4105CI1 PTS System D5G00_14800 ENOG4106J39 exported protein D5G00_14805 ENOG4105EIP mannose-6-phosphate isomerase D5G00_14810 ENOG4107GFK fumarate D5G00_14815 ENOG4105C9Q fumarate hydratase class II D5G00_14825 ENOG4105JJR Histidine kinase D5G00_14830 ENOG4105CPN adenine deaminase D5G00_14835 ENOG4105FCK Membrane D5G00_14845 ENOG4107EXC regulatoR D5G00_14860 ENOG4105C5D exported protein D5G00_14865 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) D5G00_14870 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) D5G00_14875 ENOG4105DSF transport protein D5G00_14895 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap D5G00_14905 ENOG4105D94 Major Facilitator Superfamily D5G00_14910 ENOG4106NZI LysR family Transcriptional regulator D5G00_14920 ENOG4105DAG ROK family D5G00_14925 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) D5G00_14935 ENOG4108IJ8 ABC transporter D5G00_14940 ENOG4105E90 ABC transporter D5G00_14945 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system D5G00_14950 ENOG4108U0I binding-protein-dependent transport systems inner membrane Component D5G00_14955 ENOG4108NEM leader-binding protein dmsD D5G00_14960 ENOG4107KGK dmso reductase anchor subunit D5G00_14965 ENOG4105QAX Iron-sulfur D5G00_14970 ENOG4105C3J Cysteine desulfurase D5G00_14975 ENOG4107QY8 reductase D5G00_14980 ENOG4105KBG Protein of unknown function (DUF1161) D5G00_14990 ENOG4108MK9 spermidine N(1)-acetyltransferase D5G00_15020 ENOG4105DEI Mannitol dehydrogenase D5G00_15025 ENOG41061EV selenium-binding protein YdfZ D5G00_15030 ENOG4107XBN GntR Family Transcriptional Regulator D5G00_15035 ENOG4105EMU Dehydrogenase D5G00_15050 ENOG4108WTK competence damage-inducible protein D5G00_15055 ENOG4108YDI single-species biofilm formation on inanimate substrate D5G00_15070 ENOG4108594 Permease of the drug metabolite transporter D5G00_15075 ENOG4106DNR multiple antibiotic resistance protein D5G00_15085 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes D5G00_15100 ENOG4105EGI Transcriptional regulator D5G00_15105 ENOG4105C26 Dehydrogenase D5G00_15115 ENOG4105M0C cytoplasmic protein D5G00_15120 ENOG4105FFC UPF0187 protein D5G00_15145 ENOG4105MVP hydrogenase-1 operon protein HyaF D5G00_15185 ENOG4105C6F GntR Family Transcriptional Regulator D5G00_15190 ENOG4105CPQ Dehydrogenase D5G00_15195 ENOG4108I5G Major Facilitator superfamily D5G00_15225 ENOG41060NJ transcriptional regulator D5G00_15230 ENOG4105DFD Na H antiporter D5G00_15235 ENOG4105C87 Aminotransferase class I and II D5G00_15250 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) D5G00_15260 ENOG4105XXV Acid-resistance protein D5G00_15265 ENOG4108Z9K Osmotically inducible protein D5G00_15270 ENOG4105TPS biofilm-dependent modulation protein D5G00_15285 ENOG4105DQ4 alcohol dehydrogenase D5G00_15290 ENOG4108MG3 formate dehydrogenase D5G00_15295 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein D5G00_15335 ENOG4107QND Nitrite extrusion protein D5G00_15340 ENOG4105CRU nitrate reductase, alpha subunit D5G00_15345 ENOG4108IUE nitrate reductase beta subunit D5G00_15350 ENOG4108NZN Respiratory nitrate reductase 2 delta chain D5G00_15355 ENOG4105D0D Nitrate reductase 2, gamma subunit D5G00_15360 ENOG4105JAB phenazine biosynthesis protein, phzf family D5G00_15365 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase D5G00_15380 ENOG4105C85 amino acid D5G00_15390 ENOG4108NS2 receptor D5G00_15395 ENOG4105CHB tonB-dependent Receptor D5G00_15400 ENOG4108WYP Transcriptional regulator D5G00_15405 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein D5G00_15410 ENOG4108Z7F N-acetyltransferase D5G00_15415 ENOG4108T9Y Inner membrane protein ydcZ D5G00_15420 ENOG4105R71 cytoplasmic protein D5G00_15440 ENOG410654E Membrane D5G00_15455 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family D5G00_15460 ENOG4108UQS dipeptidase D5G00_15480 ENOG4105RR0 Protein of unknown function (DUF2554) D5G00_15485 ENOG4105CFP Peptidase U32 D5G00_15490 ENOG4108JCI Transcriptional regulator D5G00_15495 ENOG4105DKK Benzoate D5G00_15500 ENOG4108KKZ (LipO)protein D5G00_15505 ENOG41088CC tellurite resistance protein tehB D5G00_15510 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein D5G00_15515 ENOG4107WE3 acetyltransferase YdcK D5G00_15520 ENOG4108Z9I -acetyltransferase D5G00_15525 ENOG4105CN9 Peptidase m42 family protein D5G00_15530 ENOG4105K18 The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) D5G00_15535 ENOG4105DT3 PTS system, galactitol-specific IIc component D5G00_15540 ENOG4106P19 photosystem i assembly btpa D5G00_15545 ENOG4108XBJ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) D5G00_15550 ENOG4108RK0 3-epimerase D5G00_15555 ENOG4108PQ7 sgc region transcriptional regulator D5G00_15570 ENOG4108YYC ycei family D5G00_15575 ENOG4105DJ9 glucan biosynthesis protein D5G00_15580 ENOG4105EBR Carboxylesterase D5G00_15585 ENOG4105E32 cytoplasmic protein D5G00_15590 ENOG4105DDW LysR family Transcriptional regulator D5G00_15595 ENOG4105C8Q Methyl-accepting chemotaxis D5G00_15625 ENOG4107ZUJ lipid metabolic process D5G00_15640 ENOG4105E5Q amino acid AbC transporter D5G00_15650 ENOG4105E5Q amino acid AbC transporter D5G00_15660 ENOG4108WF3 methyltransferase D5G00_15665 ENOG4105CPW cytochrome b561 D5G00_15670 ENOG4107DB1 DUF218 domain D5G00_15675 ENOG4105CQ7 ATP-dependent helicase D5G00_15690 ENOG4105WXT Conserved Protein D5G00_15695 ENOG410689M (LipO)protein D5G00_15700 ENOG4107H52 Dicarboxylate transport D5G00_15705 ENOG4105C5I Dehydrogenase D5G00_15710 ENOG41090X5 Heat shock protein hslJ D5G00_15725 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) D5G00_15735 ENOG4108RW8 Universal stress protein F D5G00_15740 ENOG410814C multidrug resistance protein D5G00_15760 ENOG4105C1J atp-dependent rna helicase D5G00_15775 ENOG4105C8Q Methyl-accepting chemotaxis D5G00_15785 ENOG4108DG9 Smr protein MutS2 D5G00_15790 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) D5G00_15800 ENOG4105Q9Y Universal stress protein D5G00_15805 ENOG4105S5I Membrane D5G00_15810 ENOG4105D64 Mechanosensitive ion channel D5G00_15830 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) D5G00_15860 ENOG4106PHM regulatory protein D5G00_15875 ENOG4108XFH Transcriptional regulator D5G00_15880 ENOG4105F6U Short-chain dehydrogenase reductase Sdr D5G00_15885 ENOG4105CV8 reductase D5G00_15890 ENOG4105HEI LysR family (Transcriptional regulator D5G00_15900 ENOG4107QSI ABC, transporter D5G00_15905 ENOG4105KXI murein peptide amidase A D5G00_15910 ENOG4107S8C mandelate racemase muconate lactonizing D5G00_15915 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) D5G00_15920 ENOG4108JU8 Transcriptional regulator D5G00_15930 ENOG4105CM6 amino acid regulated cytosolic protein D5G00_15935 ENOG4105K8Z Phage shock protein D5G00_15940 ENOG4105NNG Peripheral inner membrane phage-shock protein D5G00_15945 ENOG4105FM1 phage shock protein C D5G00_15950 ENOG4105YYT phage shock protein B D5G00_15955 ENOG41087YS Phage shock protein A D5G00_15960 ENOG4105E51 psp operon transcriptional activator D5G00_15965 ENOG4108J59 Extracellular solute-binding protein, family 5 D5G00_15970 ENOG4108I5W peptide transport system, permease protein D5G00_15975 ENOG4108EU3 peptide transport system, permease D5G00_15980 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein D5G00_15985 ENOG4108JQ2 peptide transport system atp-binding protein D5G00_16010 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH D5G00_16015 ENOG4105Q4T oxidoreductase D5G00_16030 ENOG4105BZU Histidine kinase D5G00_16040 ENOG4105N2W Transcriptional regulator D5G00_16045 ENOG41061RM osmotically inducible lipoprotein D5G00_16050 ENOG4108ZJT translation initiation factor, Sui1 D5G00_16060 ENOG4105CFV Tetratricopeptide repeat protein D5G00_16065 ENOG4105Q4A inner membrane protein yciS D5G00_16075 ENOG4105EYK Phosphatidylglycerophosphatase B D5G00_16085 ENOG4107QM5 aconitate hydratase D5G00_16100 ENOG4107R11 Transcriptional regulator D5G00_16105 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) D5G00_16115 ENOG4105RKX Protein of unknown function (DUF2498) D5G00_16120 ENOG4105ERU peptidase D5G00_16125 ENOG4105UBK short-chain dehydrogenase reductase D5G00_16130 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase D5G00_16135 ENOG4105FE9 pseudouridine synthase D5G00_16140 ENOG4107RTD sua5 ycio yrdc ywlc family protein D5G00_16145 ENOG4105DB7 PHP domain protein D5G00_16155 ENOG4105CRQ synthase (Component I) D5G00_16160 ENOG4108EFP Anthranilate synthase component II D5G00_16165 ENOG4105DK0 Indole-3-glycerol phosphate synthase D5G00_16185 ENOG4108Z9Z response to DNA damage stimulus D5G00_16190 ENOG4108N8X transition metal ion binding D5G00_16195 ENOG4105WEF catalase D5G00_16200 ENOG4105EIF outer membrane protein W D5G00_16205 ENOG4105PI0 Ferredoxin D5G00_16220 ENOG4105NAU thioesterase Superfamily protein D5G00_16225 ENOG410822N TonB family D5G00_16230 ENOG4105K9H YciI-like protein D5G00_16245 ENOG4105EYW Ion transport protein D5G00_16250 ENOG4108JQ7 (ABC) transporter D5G00_16255 ENOG4105C3U ABC transporter D5G00_16260 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component D5G00_16265 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component D5G00_16270 ENOG4107QSI ABC, transporter D5G00_16280 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein D5G00_16285 ENOG4108EKI Dehydrogenase D5G00_16300 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase D5G00_16305 ENOG4105I93 response regulator D5G00_16310 ENOG4105D78 K07001 NTE family protein D5G00_16320 ENOG4105CIY formyltetrahydrofolate deformylase D5G00_16370 ENOG41076YT nitrate reductase, gamma subunit D5G00_16375 ENOG4105R3A Nitrate reductase D5G00_16380 ENOG4108IUE nitrate reductase beta subunit D5G00_16385 ENOG4105CRU nitrate reductase, alpha subunit D5G00_16400 ENOG4105BZU Histidine kinase D5G00_16405 ENOG4105WH1 Two component transcriptional regulator luxr family D5G00_16410 ENOG4105ID0 Putative invasin D5G00_16415 ENOG41090EX DsrE family D5G00_16420 ENOG4105WS7 Cation transport regulator D5G00_16425 ENOG4105EWV Sodium calcium exchanger membrane region D5G00_16435 ENOG41063JG Transcriptional regulator D5G00_16440 ENOG4108YY7 Invasion gene expression up-regulator SirB D5G00_16445 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) D5G00_16470 ENOG4105C5T Phosphoribosyl pyrophosphate synthase D5G00_16475 ENOG4105CHH sulfate transporter D5G00_16480 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria D5G00_16490 ENOG4105C3G gtp-binding protein D5G00_16510 ENOG4105E3S small subunit D5G00_16520 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit D5G00_16525 ENOG4108USZ hydrogenase D5G00_16530 ENOG4108VXY Hydrogenase-1 operon protein HyaE D5G00_16535 ENOG4105MVP hydrogenase-1 operon protein HyaF D5G00_16540 ENOG4105C4M (Ubiquinol oxidase) subunit I D5G00_16545 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii D5G00_16555 ENOG4105D82 Glutamate dehydrogenase D5G00_16570 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) D5G00_16580 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A D5G00_16590 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) D5G00_16600 ENOG4105ED1 spovr family D5G00_16625 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation D5G00_16640 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase D5G00_16655 ENOG4107QMS site-determining protein D5G00_16665 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) D5G00_16670 ENOG4105CEY Amp-dependent synthetase and ligase D5G00_16680 ENOG4105Y4Z Outer Membrane Lipoprotein D5G00_16685 ENOG41072GX Peptidase M22 Glycoprotease D5G00_16690 ENOG4105DVT helicase D5G00_16695 ENOG4105M4H endoribonuclease L-psp D5G00_16705 ENOG4105CRQ synthase (Component I) D5G00_16715 ENOG4105EJQ L-serine dehydratase D5G00_16720 ENOG4107XTP (EAL) domain protein D5G00_16725 ENOG4105EE5 Membrane protein terC D5G00_16735 ENOG4108EQA pts system D5G00_16740 ENOG4105ETZ PTS System D5G00_16745 ENOG4105F3R pts system mannose fructose sorbose family iid D5G00_16765 ENOG4105DHI Methyltransferase D5G00_16770 ENOG4105CJN penicillin-binding protein D5G00_16775 ENOG4105VEQ Cold shock protein D5G00_16780 ENOG410610J Protein of unknown function (DUF2627) D5G00_16785 ENOG4105Q3Y exported protein D5G00_16800 ENOG4105J4Q Transcriptional regulator D5G00_16805 ENOG4105C0R drug resistance transporter emrb qaca subfamily D5G00_16815 ENOG4105CN1 protease D5G00_16825 ENOG4108ZGC gaf domain protein D5G00_16830 ENOG4105H2K paraquat-inducible protein a D5G00_16835 ENOG4105DY2 Paraquat-inducible protein b D5G00_16845 ENOG4105WT8 Protein of unknown function (DUF1480) D5G00_16850 ENOG4105UVW uncharacterized protein yebW D5G00_16855 ENOG4108R1E Serine threonine protein phosphatase 1 D5G00_16865 ENOG4106EWC guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling D5G00_16870 ENOG41064WM Uncharacterized protein YcgX D5G00_16880 ENOG4105VEV -acetyltransferase D5G00_16980 ENOG4108YV9 Protein of unknown function (DUF2514) D5G00_16995 ENOG4108I1J Integrase D5G00_17020 ENOG4105UZW Tail fiber assembly protein D5G00_17025 ENOG4108X9F tail fiber protein D5G00_17065 ENOG4108T1M outer membrane protein x D5G00_17140 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 D5G00_17200 ENOG4105EUZ Beta-lactamase domain protein D5G00_17220 ENOG4105ZTP Protein of unknown function (DUF1376) D5G00_17260 ENOG41076J9 exonuclease VIII D5G00_17265 ENOG4108PNI recT protein D5G00_17285 ENOG4108I1J Integrase D5G00_17295 ENOG4105NKT exported protein D5G00_17300 ENOG4108PNC copper resistance D5G00_17305 ENOG4105FXM Copper resistance protein D5G00_17310 ENOG4105MPK DNA polymerase III subunit theta D5G00_17315 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase D5G00_17320 ENOG4105UMD exodeoxyribonuclease X D5G00_17325 ENOG4105CUG Oligopeptidase b D5G00_17330 ENOG4108Q2J Inner membrane protein YebE D5G00_17340 ENOG4105X2V dna damage-inducible protein D5G00_17350 ENOG4108UHU Aldolase D5G00_17355 ENOG4105C01 Dihydroxy-acid dehydratase D5G00_17360 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase D5G00_17370 ENOG4106KNT transcriptional regulator D5G00_17375 ENOG4105CA9 Pyruvate kinase D5G00_17380 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase D5G00_17390 ENOG4105DR5 peptidase D5G00_17395 ENOG4105NXV High-affinity zinc uptake system protein D5G00_17405 ENOG4105FAV ABC, transporter D5G00_17425 ENOG4107S01 Repressor protein MetJ D5G00_17445 ENOG4108TIT dATP pyrophosphohydrolase D5G00_17455 ENOG4105D3W isochorismatase D5G00_17460 ENOG41081XQ Conserved Protein D5G00_17465 ENOG4105WJG Glutathione D5G00_17490 ENOG4106ZCM YecM protein D5G00_17510 ENOG4105IRD Flagellar protein FlhE D5G00_17515 ENOG4105D7B Flagellar biosynthesis protein flha D5G00_17520 ENOG4105D00 flagellar biosynthetic protein flhB D5G00_17525 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) D5G00_17530 ENOG4108VYJ response regulator receiver protein D5G00_17540 ENOG4105BZU Histidine kinase D5G00_17545 ENOG4105C8Q Methyl-accepting chemotaxis D5G00_17550 ENOG4108V3W Chemotaxis protein, CheW D5G00_17555 ENOG4105CBS Chea signal transduction histidine kinase D5G00_17560 ENOG4105ER2 Ompa motb domain protein D5G00_17565 ENOG4107RD7 Flagellar Motor Protein, MotA D5G00_17570 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region D5G00_17575 ENOG4105GEH Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity) D5G00_17585 ENOG4108VA4 Universal stress protein D5G00_17595 ENOG4108K4C ec 3.1.3.12 D5G00_17610 ENOG4108UEC Ferritin-like protein D5G00_17620 ENOG4105P23 (LipO)protein D5G00_17625 ENOG41090A1 ferritin D5G00_17630 ENOG4105VVZ metal-binding protein D5G00_17635 ENOG4105E0U tyrosine-specific transport protein D5G00_17685 ENOG4105WH1 Two component transcriptional regulator luxr family D5G00_17695 ENOG4105XVG cytoplasmic protein D5G00_17700 ENOG4105VJY transcriptional regulator D5G00_17705 ENOG4105CDA abc transporter atp-binding protein D5G00_17710 ENOG4105E5Q amino acid AbC transporter D5G00_17720 ENOG4105EAB amino acid AbC transporter D5G00_17725 ENOG4108M9K flagella biosynthesis protein FliZ D5G00_17730 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) D5G00_17735 ENOG4108C80 FliB family D5G00_17750 ENOG4105DTS flagellar hook-associated D5G00_17755 ENOG4105MQ3 flagellar protein FliS D5G00_17765 ENOG4105E5K Alpha-amylase D5G00_17770 ENOG4105JCU Inherit from NOG: (Lipo)protein D5G00_17775 ENOG41066VF YeeE YedE family protein D5G00_17780 ENOG4105KSU Redox protein D5G00_17795 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) D5G00_17800 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) D5G00_17805 ENOG41090PJ Flagellar assembly protein D5G00_17810 ENOG4108JIR Flagellum-specific ATP synthase D5G00_17815 ENOG4105GSA Flagellar export protein flij D5G00_17820 ENOG4105WF4 Flagellar hook-length control protein D5G00_17825 ENOG4107ZI8 flagellar basal body-associated protein flil D5G00_17830 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) D5G00_17835 ENOG4105DD5 Flagellar motor switch protein D5G00_17840 ENOG4105K0P flagellar biosynthesis protein D5G00_17845 ENOG4105CN7 Flagellar biosynthetic protein FliP D5G00_17850 ENOG4105VS8 Flagellar biosynthetic protein fliq D5G00_17855 ENOG4105D19 Role in flagellar biosynthesis (By similarity) D5G00_17860 ENOG4107TKS colanic acid capsular biosynthesis activation protein A D5G00_17870 ENOG4105YX3 cellular response to acidity D5G00_17885 ENOG4105VNZ cytoplasmic protein D5G00_17890 ENOG4105CKW Inner membrane protein yedI D5G00_17895 ENOG4105FDR Membrane D5G00_17900 ENOG41090BB DNA mismatch endonuclease (vsr) D5G00_17905 ENOG4105DVF Cytosine-specific methyltransferase D5G00_17910 ENOG4105EST Metal Dependent Phosphohydrolase D5G00_17915 ENOG4105Y0K Inner membrane protein YedR D5G00_17920 ENOG4105FCK Membrane D5G00_17925 ENOG4105FCK Membrane D5G00_17950 ENOG410600K aminopeptidase D5G00_17970 ENOG4105CNA YD repeat protein D5G00_17980 ENOG4105CNA YD repeat protein D5G00_17985 ENOG4105CS6 Rhs element vgr protein D5G00_17990 ENOG4108WC9 type VI secretion system effector, hcp1 family D5G00_18045 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit D5G00_18070 ENOG4105GMB type VI secretion system effector, hcp1 family D5G00_18110 ENOG4107RJ5 oxidoreductase D5G00_18120 ENOG4108QGT oligogalacturonate-specific porin D5G00_18130 ENOG4105C9S Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity) D5G00_18140 ENOG4107RJ1 sodium solute D5G00_18145 ENOG4105QEK Transcriptional regulator D5G00_18150 ENOG4105D5M phosphate starvation-inducible protein D5G00_18160 ENOG4105CK7 Sodium proline symporter D5G00_18180 ENOG4108R86 Transcriptional regulator D5G00_18185 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 D5G00_18200 ENOG4105XH3 D5G00_18205 ENOG4105D6F Phosphatase D5G00_18210 ENOG4105N2G alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen D5G00_18215 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) D5G00_18220 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) D5G00_18290 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase D5G00_18295 ENOG4105C26 Dehydrogenase D5G00_18305 ENOG4108V8F Transcriptional regulator, MarR family D5G00_18310 ENOG4105EFA 4-hydroxyphenylacetate D5G00_18335 ENOG4105CK6 Two component transcriptional regulator (Winged helix family D5G00_18340 ENOG4107ZY3 Histidine kinase D5G00_18355 ENOG4106YSC D5G00_18360 ENOG4108N4M Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns 3-P and prevents the transition of PtdIns 3-P to PtdIns 3,5-P2. It is one of the known effectors injected by Salmonella into the host cell and is required for invasion and for an efficient generation and maintenance of Salmonella-containing vacuole (SVC). Alteration of the phosphoinositide composition of the plasma membrane causes membrane ruffling and actin cytoskeleton rearrangements. The persistence of PtdIns 3-P diverts the SCV from the endocytic pathway resulting in enlarged vesicles, which are essential to create a favorable environment where Salmonella can replicate and avoid immune defenses of the host cell D5G00_18375 ENOG41084BJ Pentapeptide repeat protein D5G00_18390 ENOG4108MN8 Membrane D5G00_18400 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 D5G00_18410 ENOG4108V1U phospholipid-binding protein D5G00_18425 ENOG4105K4P CoA-binding domain protein D5G00_18440 ENOG41088T4 Helicase IV D5G00_18445 ENOG410901E Membrane D5G00_18450 ENOG4105EM2 membrane D5G00_18455 ENOG4108RZ1 DNA transformation protein D5G00_18465 ENOG4105UYK outer membrane protein a D5G00_18475 ENOG4105DAN ATP-dependent protease D5G00_18485 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) D5G00_18490 ENOG4108Q2G (LipO)protein D5G00_18495 ENOG4105DY2 Paraquat-inducible protein b D5G00_18500 ENOG4105F1S paraquat-inducible protein a D5G00_18505 ENOG4105C5H ABC transporter D5G00_18515 ENOG4105QVC MOSC domain-containing protein D5G00_18520 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) D5G00_18530 ENOG4105CD8 aminopeptidase N D5G00_18535 ENOG4105Y50 Virulence Protein D5G00_18550 ENOG4108RAV Conserved protein D5G00_18560 ENOG4106EE1 D5G00_18575 ENOG4105UZW Tail fiber assembly protein D5G00_18580 ENOG410685N tail fiber protein D5G00_18670 ENOG4105M6F mutator MutT protein D5G00_18700 ENOG4108YV9 Protein of unknown function (DUF2514) D5G00_18705 ENOG4105NVB glycoside hydrolase, family 19 D5G00_18715 ENOG4105HGD Antitermination protein D5G00_18745 ENOG4105MEA DNA damage-inducible protein i D5G00_18775 ENOG4105JBR DNA replication protein D5G00_18800 ENOG41076J9 exonuclease VIII D5G00_18820 ENOG4107R08 Integrase D5G00_18835 ENOG4107RCH Diaminopropionate ammonia-lyase D5G00_18855 ENOG4105FCK Membrane D5G00_18860 ENOG4105CGF Aromatic amino acid aminotransferase D5G00_18865 ENOG4105C5X domain protein D5G00_18870 ENOG4105EAQ (twin-arginine translocation) pathway signal D5G00_18880 ENOG4105DIT ErfK YbiS YcfS YnhG family protein D5G00_18890 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) D5G00_18900 ENOG4106371 Methyltransferase D5G00_18905 ENOG4107S90 membrAne D5G00_18910 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups D5G00_18925 ENOG4105T0Z Conserved Protein D5G00_18940 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 D5G00_18950 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) D5G00_18955 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) D5G00_18965 ENOG4108K0D peptidase, M48 D5G00_18980 ENOG4107VMU Membrane D5G00_18985 ENOG4105DDY UPF0142 protein ycaO D5G00_18990 ENOG4105TMB Formate nitrite transporter D5G00_18995 ENOG4105C6N Formate acetyltransferase D5G00_19000 ENOG4105GUS D5G00_19010 ENOG4105F1A Pyruvate formate-lyase D5G00_19015 ENOG4105E5D amino acid D5G00_19025 ENOG4107KGK dmso reductase anchor subunit D5G00_19030 ENOG4105QAX Iron-sulfur D5G00_19035 ENOG4107QY8 reductase D5G00_19045 ENOG4105D1H recombination factor protein RarA D5G00_19055 ENOG4105CNU cell division protein FtsK D5G00_19060 ENOG4105EW9 transcriptional regulator AsnC family D5G00_19070 ENOG4105C3M thioredoxin reductase D5G00_19075 ENOG4108JJ9 ABC, transporter D5G00_19080 ENOG4108JJ8 (ABC) transporter D5G00_19095 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) D5G00_19100 ENOG4105HEI LysR family (Transcriptional regulator D5G00_19105 ENOG4105EUB pirin domain protein D5G00_19110 ENOG4105CHJ isochorismatase hydrolase D5G00_19130 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit D5G00_19140 ENOG4105VEQ Cold shock protein D5G00_19145 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) D5G00_19150 ENOG4105DJY efflux transporter, rnd family, mfp subunit D5G00_19155 ENOG4108MJ5 VirK protein D5G00_19160 ENOG4105CPB ATP-dependent endonuclease of the OLD family D5G00_19170 ENOG4105DWU Membrane D5G00_19180 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) D5G00_19185 ENOG4105C7K acetolactate synthase D5G00_19190 ENOG4105C5W Aldolase D5G00_19200 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase D5G00_19205 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase D5G00_19215 ENOG41064MM (LipO)protein D5G00_19220 ENOG4105E5Z arginine transporter ATP-binding subunit D5G00_19225 ENOG4106PMH Extracellular solute-binding protein family 3 D5G00_19230 ENOG4105GBT ABC transporter D5G00_19235 ENOG4105DMR ABC, transporter D5G00_19240 ENOG4106TNF Periplasmic binding protein D5G00_19270 ENOG4105RBQ inner membrane protein ybjO D5G00_19275 ENOG4105D38 putrescine abc transporter D5G00_19280 ENOG4105F38 ABC transporter, permease D5G00_19285 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) D5G00_19290 ENOG4107RUE extracellular solute-binding protein family 1 D5G00_19295 ENOG4108RMJ sensory transduction regulator D5G00_19305 ENOG4108DBC nitroreductase D5G00_19310 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress D5G00_19315 ENOG41090BQ Glutaredoxin D5G00_19320 ENOG4105GWF inner membrane protein YbjM D5G00_19340 ENOG4108RFG Tetr family transcriptional regulator D5G00_19345 ENOG4106UW1 Major Facilitator superfamily D5G00_19350 ENOG4108HCJ Hydrolase D5G00_19355 ENOG4107QF7 multi-drug D5G00_19360 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase D5G00_19365 ENOG4107FB0 transcriptional regulator DeoR family D5G00_19370 ENOG4105DZ1 carboxypeptidase D5G00_19375 ENOG4108TGY Glutathione S-transferase D5G00_19380 ENOG4105D8V Glucose sorbosone dehydrogenase D5G00_19390 ENOG4105CY2 Citrate transporter D5G00_19395 ENOG4108KB2 LysR family Transcriptional regulator D5G00_19400 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase D5G00_19405 ENOG4105C1G acyl-Coa dehydrogenase D5G00_19415 ENOG4105C10 Electron transfer flavoprotein D5G00_19420 ENOG4105BZJ Electron transfer flavoprotein D5G00_19425 ENOG4105CI0 Citrate lyase D5G00_19430 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway D5G00_19450 ENOG4105DEF Extracellular solute-binding protein, family 5 D5G00_19460 ENOG4105D44 asparaginase D5G00_19465 ENOG4105CVM Molybdenum cofactor synthesis domain protein D5G00_19470 ENOG4105D06 uba thif-type nad fad binding protein D5G00_19475 ENOG4105F1A Pyruvate formate-lyase D5G00_19480 ENOG4105C6N Formate acetyltransferase D5G00_19485 ENOG4108HCJ Hydrolase D5G00_19490 ENOG41072TH Protein of unknown function (DUF1479) D5G00_19515 ENOG4105C5H ABC transporter D5G00_19520 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein D5G00_19525 ENOG4105F4P )-transporter D5G00_19530 ENOG4105KST dependent repressor D5G00_19540 ENOG4108I6E Sulfatase D5G00_19545 ENOG4108T1M outer membrane protein x D5G00_19560 ENOG4107R0W ABC transporter D5G00_19565 ENOG4105E5Q amino acid AbC transporter D5G00_19570 ENOG4105CDA abc transporter atp-binding protein D5G00_19575 ENOG4105D8X mechanosensitive ion channel D5G00_19585 ENOG4105KSC Transcriptional regulator, TraR DksA family D5G00_19590 ENOG4105VR4 UPF0379 protein ybiJ D5G00_19595 ENOG4108MTB glycosyl transferase family D5G00_19600 ENOG4105DVT helicase D5G00_19605 ENOG4105C1J atp-dependent rna helicase D5G00_19610 ENOG4107MVR Transcriptional regulator D5G00_19620 ENOG4105CJ1 ABC, transporter D5G00_19625 ENOG4107QWP ABC-2 type transporter D5G00_19630 ENOG4107QWP ABC-2 type transporter D5G00_19635 ENOG4105I9U inner membrane protein ybhQ D5G00_19640 ENOG4105X23 Endonuclease Exonuclease phosphatase D5G00_19645 ENOG4105DZQ phospholipase D Transphosphatidylase D5G00_19650 ENOG4107UXM Membrane D5G00_19675 ENOG4105HFZ Membrane D5G00_19680 ENOG4108ZAF Molybdopterin D5G00_19685 ENOG4105M00 molybdopterin converting factor, subunit 1 D5G00_19695 ENOG4108RIR Molybdenum cofactor biosynthesis protein D5G00_19705 ENOG4105CHW UPF0052 protein D5G00_19730 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) D5G00_19735 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) D5G00_19750 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) D5G00_19755 ENOG4108V1U phospholipid-binding protein D5G00_19785 ENOG4105NBR Pectinesterase D5G00_19795 ENOG4108K4B hydrolase D5G00_19805 ENOG4105E0C molybdate abc transporter D5G00_19810 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein D5G00_19815 ENOG410680R Protein of unknown function (DUF2592) D5G00_19820 ENOG4105F4R Transcriptional regulator mode D5G00_19825 ENOG4105DKW ABC transporter D5G00_19835 ENOG4105CMR udp-glucose 4-epimerase D5G00_19840 ENOG4105F0Z galactose-1-phosphate uridylyltransferase D5G00_19850 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) D5G00_19870 ENOG4105EHG Permease protein D5G00_19875 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase D5G00_19880 ENOG4105D9Q decarboxylase (Beta subunit) D5G00_19885 ENOG4107QSA Oxaloacetate decarboxylase D5G00_19895 ENOG4107QWE )-transporter D5G00_19905 ENOG4105C5Q Transcriptional regulator D5G00_19910 ENOG4106DSS Tartrate dehydratase subunit alpha D5G00_19915 ENOG4107GFK fumarate D5G00_19920 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) D5G00_19925 ENOG4105JND homeobox protein D5G00_19930 ENOG4105PGM cation diffusion facilitator family transporter D5G00_19935 ENOG4106Z1T Nicotinamide Mononucleotide Transporter D5G00_19975 ENOG4105UFD tol-pal system protein YbgF D5G00_19980 ENOG4105KCK Peptidoglycan-associated lipoprotein D5G00_19990 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA D5G00_19995 ENOG4105M8F Biopolymer transport protein exbD tolR D5G00_20000 ENOG4105E02 MotA TolQ exbB proton channel D5G00_20005 ENOG4107YD3 Thioesterase D5G00_20010 ENOG4105KJB cyd operon protein YbgE D5G00_20020 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii D5G00_20025 ENOG4105C4M (Ubiquinol oxidase) subunit I D5G00_20030 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha D5G00_20040 ENOG4105C7S Dehydrogenase D5G00_20045 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 D5G00_20050 ENOG4105E33 succinate dehydrogenase D5G00_20055 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) D5G00_20060 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein D5G00_20065 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit D5G00_20080 ENOG4105BZN citrate synthase D5G00_20085 ENOG4108KK1 membrane protein AbrB duplication D5G00_20100 ENOG4107R7A Allophanate hydrolase subunit 2 D5G00_20105 ENOG4105P4J Allophanate hydrolase, subunit 1 D5G00_20110 ENOG4107QNR UPF0135 protein D5G00_20125 ENOG4105CVP deoxyribo-dipyrimidine photolyase D5G00_20130 ENOG4105XIQ Protein of unknown function (DUF2517) D5G00_20155 ENOG4105C08 Histidine kinase D5G00_20160 ENOG4105EEX Two component transcriptional regulator (Winged helix family D5G00_20170 ENOG4105CXN decarboxylase D5G00_20175 ENOG4105D5Q Arginine ornithine antiporter D5G00_20185 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 D5G00_20190 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) D5G00_20195 ENOG4105EV9 Alpha Beta Hydrolase D5G00_20200 ENOG4105NNH LexA regulated protein D5G00_20205 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) D5G00_20210 ENOG41090R7 Ferric uptake D5G00_20215 ENOG4106P55 Transcriptional regulator D5G00_20220 ENOG4107EFR Flavocytochrome c D5G00_20225 ENOG41079YP Citrate utilization protein b D5G00_20230 ENOG4105CSH Transporter D5G00_20235 ENOG4105GX6 (LipO)protein D5G00_20255 ENOG4105CI1 PTS System D5G00_20265 ENOG4105CE4 GlcNAc 6-P deacetylase D5G00_20270 ENOG4105E2R ROK family D5G00_20275 ENOG4105D4U had-superfamily hydrolase, subfamily iia D5G00_20280 ENOG4105CAQ asparagine synthetase D5G00_20320 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family D5G00_20330 ENOG4105C9A Phoh family D5G00_20340 ENOG4108JU5 Magnesium and cobalt efflux protein D5G00_20345 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) D5G00_20350 ENOG4107RP9 extracellular solute-binding protein, family 3 D5G00_20355 ENOG4105EAD ABC transporter D5G00_20360 ENOG4105DRP amino acid AbC transporter D5G00_20365 ENOG4105CDA abc transporter atp-binding protein D5G00_20380 ENOG4105F7F Chaperone D5G00_20385 ENOG4105QFC Hsc56 co-chaperone of HscC D5G00_20390 ENOG41069CF Protein of unknown function (DUF1266) D5G00_20395 ENOG4105QFC Hsc56 co-chaperone of HscC D5G00_20400 ENOG41069CF Protein of unknown function (DUF1266) D5G00_20410 ENOG4107PAI alpha helical protein D5G00_20420 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) D5G00_20445 ENOG4105DJF DNA polymerase III, delta' subunit D5G00_20450 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) D5G00_20455 ENOG4107QZB decarboxylase D5G00_20460 ENOG4108TGR phosphatase D5G00_20465 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) D5G00_20475 ENOG4105CJN penicillin-binding protein D5G00_20480 ENOG4105CNI cell division protein FtsW D5G00_20485 ENOG4105K6T rare lipoprotein A D5G00_20490 ENOG4105DZ1 carboxypeptidase D5G00_20495 ENOG4108Z43 UPF0250 protein D5G00_20505 ENOG41064T2 transcriptional regulator, lysR family D5G00_20520 ENOG4107QPI nitrilase cyanide hydratase and apolipoprotein n-acyltransferase D5G00_20530 ENOG4105VEQ Cold shock protein D5G00_20545 ENOG4105CEE C4-dicarboxylate transporter D5G00_20550 ENOG4106YYS transcriptional regulatory protein D5G00_20560 ENOG4105DUA (citrate (pro-3S)-lyase ligase D5G00_20565 ENOG4105XGS Covalent carrier of the coenzyme of citrate lyase (By similarity) D5G00_20570 ENOG4105CI0 Citrate lyase D5G00_20575 ENOG4105CHY citrate lyase, alpha D5G00_20580 ENOG4105YGP holo-ACP synthase CitX D5G00_20590 ENOG4107QPK )-transporter D5G00_20595 ENOG4105KTS ribonuclease D5G00_20605 ENOG4105NXH GreA GreB family elongation factor D5G00_20610 ENOG4105E2A Dehydrogenase D5G00_20620 ENOG4108U51 Universal stress protein D5G00_20630 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein D5G00_20635 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) D5G00_20640 ENOG4107QY8 reductase D5G00_20650 ENOG4108JU3 Alkyl hydroperoxide reductase D5G00_20655 ENOG4105D3R alkyl hydroperoxide reductase D5G00_20660 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase D5G00_20670 ENOG4105DQS Transcriptional regulator D5G00_20675 ENOG4105BZV Phosphoadenosine phosphosulfate reductase D5G00_20680 ENOG4105GTN ParB Domain Protein Nuclease D5G00_20685 ENOG4105CHM Aminotransferase D5G00_20695 ENOG4105VCD cytoplasmic protein D5G00_20700 ENOG4105D22 carbon starvation protein D5G00_20710 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase D5G00_20715 ENOG4105WQI isochorismatase D5G00_20720 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase D5G00_20725 ENOG4105E4F Isochorismate synthase D5G00_20730 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein D5G00_20735 ENOG4105E8G Major facilitator Superfamily D5G00_20740 ENOG4105DQ5 transport system permease protein D5G00_20745 ENOG4105TVJ transport system, permease D5G00_20750 ENOG4105E0A ABC, transporter D5G00_20755 ENOG4108QY5 Ferric enterobactin transport protein D5G00_20760 ENOG4105C0W non-ribosomal peptide synthetase D5G00_20765 ENOG41085A6 mbth domain-containing protein D5G00_20770 ENOG4105E93 esterase D5G00_20775 ENOG4107RNH Outer membrane receptor FepA D5G00_20780 ENOG4108TSE Transferase D5G00_20790 ENOG4105WQ6 Membrane D5G00_20795 ENOG4105HFT AraC family transcriptional regulator D5G00_20800 ENOG41067SE Tetr family transcriptional regulator D5G00_20805 ENOG4105MSB protein, conserved in bacteria D5G00_20810 ENOG4108RCM Nitroreductase D5G00_20825 ENOG4105CUY Mechanosensitive ion channel D5G00_20830 ENOG4105C85 amino acid D5G00_20840 ENOG4108KBJ Inner membrane protein YkgB D5G00_20845 ENOG41066GK UPF0379 protein ykgI D5G00_20855 ENOG4107QN2 dihydrolipoyl dehydrogenase D5G00_20860 ENOG4108K01 transcriptional regulator D5G00_20870 ENOG4105GR3 Histidine kinase D5G00_20880 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) D5G00_20885 ENOG4105CKK Glycosyl transferase, family 2 D5G00_20900 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) D5G00_20905 ENOG4105CKK Glycosyl transferase, family 2 D5G00_21030 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 D5G00_21090 ENOG4105NY2 NinB protein D5G00_21095 ENOG4105CDU Replicative dna helicase D5G00_21170 ENOG4108UUM single-stranded DNA-binding protein D5G00_21225 ENOG4108KU3 Integrase D5G00_21240 ENOG4106KCD HTH_LUXR D5G00_21250 ENOG4106721 fimbriae Y protein D5G00_21255 ENOG4108Q9V regulatoR D5G00_21260 ENOG4108ZI2 Fimbrial protein D5G00_21265 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) D5G00_21270 ENOG4105CW0 outer membrane usher protein D5G00_21275 ENOG4108AF8 Chaperone D5G00_21285 ENOG4108WDE Fimbrial protein D5G00_21300 ENOG4105WQ3 Rna-binding protein D5G00_21305 ENOG4105S2T inner membrane protein YbcI D5G00_21325 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) D5G00_21340 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) D5G00_21345 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit D5G00_21350 ENOG4105C5B carbamate kinase D5G00_21355 ENOG4105G5A Protein of unknown function (DUF2877) D5G00_21360 ENOG4107REC cytoplasmic protein D5G00_21365 ENOG4107R1Q Membrane protein FdrA D5G00_21370 ENOG4105DG4 malate L-lactate dehydrogenase D5G00_21375 ENOG4105CE7 Amidase, hydantoinase carbamoylase family D5G00_21380 ENOG4105S0E allantoin catabolism protein D5G00_21385 ENOG4105BZW Glycerate kinase D5G00_21390 ENOG4105DTE Xanthine uracil vitamin C permease D5G00_21400 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease D5G00_21410 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase D5G00_21415 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) D5G00_21420 ENOG41060W2 glyoxylate carboligase D5G00_21445 ENOG4108UMI ABC transporter, permease D5G00_21450 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) D5G00_21455 ENOG4105D01 (LipO)protein D5G00_21465 ENOG4105CV6 ABC transporter, permease D5G00_21470 ENOG4108I0Y (ABC) transporter D5G00_21475 ENOG4108UJV acyl-CoA thioesterase i D5G00_21480 ENOG4105E1F short-chain dehydrogenase reductase D5G00_21485 ENOG4107QR8 Thioredoxin D5G00_21490 ENOG4105C4B ABC transporter, permease D5G00_21495 ENOG41083J0 (ABC) transporter D5G00_21500 ENOG4107QX8 SPFH domain, Band 7 family protein D5G00_21505 ENOG4105G5H Membrane D5G00_21510 ENOG4108Z6Z Transcriptional regulator D5G00_21515 ENOG4105C59 p-type ATPase D5G00_21525 ENOG4105MBR gumn family D5G00_21530 ENOG4108Z66 YbaK ebsC protein D5G00_21535 ENOG4105CGH 5'-nucleotidase D5G00_21540 ENOG4105EU0 Major facilitator Superfamily D5G00_21545 ENOG4105CKD glutathione-regulated potassium-efflux system protein D5G00_21550 ENOG4107RE1 Inosine-guanosine kinase D5G00_21590 ENOG4107QMP dna polymerase iii subunits gamma and tau D5G00_21600 ENOG4105WD1 Membrane D5G00_21605 ENOG4108URS primosomal replication protein n'' D5G00_21610 ENOG4106428 Protein of unknown function (DUF2496) D5G00_21615 ENOG4105DNE Transposase D5G00_21620 ENOG4105EGS Mechanosensitive ion channel D5G00_21625 ENOG4108IG5 Transcriptional regulator D5G00_21630 ENOG4105C1P efflux transporter, rnd family, mfp subunit D5G00_21635 ENOG4105BZS acriflavin resistance protein D5G00_21640 ENOG4108UKR Biofilm formation regulator YbaJ D5G00_21650 ENOG4108UW5 maltose o-acetyltransferase D5G00_21655 ENOG4105GSJ Inner membrane protein ylaC D5G00_21670 ENOG41066DG (EAL) domain protein D5G00_21680 ENOG41080UX Methyltransferase D5G00_21685 ENOG4108MNP Glycoprotein polysaccharide metabolism D5G00_21690 ENOG4105C29 acyl-CoA thioesterase D5G00_21695 ENOG4105BZU Histidine kinase D5G00_21700 ENOG4108YZA Nitrogen regulatory protein pii D5G00_21705 ENOG4105BZ1 (ABC) transporter D5G00_21710 ENOG4105BZ1 (ABC) transporter D5G00_21715 ENOG4108XM1 transcriptional regulator AsnC family D5G00_21740 ENOG4108TGP Thioesterase superfamily protein D5G00_21745 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein D5G00_21750 ENOG4105EIN peptidylprolyl cis-trans isomerase D5G00_21755 ENOG4105K70 DNA-binding protein D5G00_21760 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) D5G00_21790 ENOG4105M85 Bola protein D5G00_21800 ENOG4105IEY (LipO)protein D5G00_21805 ENOG4105EYM Major Facilitator superfamily D5G00_21810 ENOG4105E2S oxidase) subunit II D5G00_21815 ENOG4105BZ9 Cytochrome C oxidase, subunit I D5G00_21820 ENOG4105CCU oxidase (Subunit III) D5G00_21825 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) D5G00_21845 ENOG4107RDB Major Facilitator D5G00_21855 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) D5G00_21860 ENOG4107S0N DJ-1 family D5G00_21875 ENOG4106S9K Transcriptional regulator D5G00_21885 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) D5G00_21895 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component D5G00_21910 ENOG4105CTB Polyprenyl synthetase D5G00_21920 ENOG4105CPC Aldo Keto reductase D5G00_21925 ENOG4108ZAI phosphatidylglycerophosphatase a D5G00_21930 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) D5G00_21935 ENOG4107YIM Involved in the transcription termination process (By similarity) D5G00_21945 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) D5G00_21955 ENOG4108KIC (LipO)protein D5G00_21960 ENOG4105DRB nucleoside-specific channel-forming protein D5G00_21975 ENOG4105N1F Hnh endonuclease D5G00_21990 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) D5G00_22000 ENOG4105VIE preprotein translocase, subunit YajC D5G00_22025 ENOG4105D3R alkyl hydroperoxide reductase D5G00_22030 ENOG4107R28 alpha amylase, catalytic region D5G00_22035 ENOG4105C85 amino acid D5G00_22040 ENOG4105CWM branched-chain amino acid transport system II carrier protein D5G00_22045 ENOG4105BZU Histidine kinase D5G00_22050 ENOG4105CK6 Two component transcriptional regulator (Winged helix family D5G00_22055 ENOG4107RH8 nuclease SbcCD subunit D D5G00_22060 ENOG4105EYH Exonuclease D5G00_22065 ENOG4105F27 Major Facilitator D5G00_22070 ENOG4105DKQ ROK family D5G00_22085 ENOG4105HBA AroM protein D5G00_22090 ENOG4105SS3 D5G00_22105 ENOG4105II7 pyrroline-5-carboxylate reductase D5G00_22110 ENOG4105BZU Histidine kinase D5G00_22115 ENOG4105VIF phosphate starvation-inducible protein D5G00_22135 ENOG4105CPF Cell wall formation (By similarity) D5G00_22140 ENOG4105UNH Membrane D5G00_22145 ENOG4105FR5 inner membrane protein YaiY D5G00_22150 ENOG4107QS8 (LipO)protein D5G00_22155 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 D5G00_22165 ENOG4107R6D beta-lactam binding protein AmpH D5G00_22170 ENOG4108PNB DNA-binding transcriptional regulator D5G00_22175 ENOG4108NSE outer membrane autotransporter barrel D5G00_22180 ENOG4105D52 delta-aminolevulinic acid dehydratase D5G00_22185 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) D5G00_22190 ENOG4105DXD 2-methylcitrate dehydratase D5G00_22195 ENOG4105BZN citrate synthase D5G00_22200 ENOG4105CR4 methylisocitrate lyase D5G00_22210 ENOG4105TDT uncharacterized protein yahO D5G00_22215 ENOG4105E82 cytochrome subunit of dehydrogenase D5G00_22235 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii D5G00_22240 ENOG4105C4M (Ubiquinol oxidase) subunit I D5G00_22250 ENOG4105D8D Type III D5G00_22255 ENOG4107QMH DNA methylase D5G00_22260 ENOG4105JHE Major Facilitator Superfamily D5G00_22290 ENOG4105ENJ RND efflux system, outer membrane lipoprotein D5G00_22310 ENOG4108T1M outer membrane protein x D5G00_22325 ENOG4107XTP (EAL) domain protein D5G00_22345 ENOG4105X0I Fimbrial D5G00_22350 ENOG4108VEV chaperone D5G00_22355 ENOG4105CW0 outer membrane usher protein D5G00_22380 ENOG4105EJC lysr family transcriptional regulator D5G00_22390 ENOG4105ERH Fumarylacetoacetate hydrolase D5G00_22395 ENOG4108TFY Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) D5G00_22400 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) D5G00_22405 ENOG4105D94 Major Facilitator Superfamily D5G00_22410 ENOG4105V2F Uncharacterized protein yoac D5G00_22415 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit D5G00_22420 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit D5G00_22450 ENOG4105FCK Membrane D5G00_22470 ENOG4105CIN aminoacyl-histidine dipeptidase D5G00_22475 ENOG4108S2Y peptide Chain Release factor D5G00_22490 ENOG4105F7V ErfK ybiS ycfS ynhG family protein D5G00_22495 ENOG4105E7A Glutamine amidotransferase D5G00_22505 ENOG4107QPN acyl-Coa dehydrogenase D5G00_22510 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase D5G00_22520 ENOG4105T40 surface antigen msp4 family protein D5G00_22530 ENOG4105W7K Transcriptional regulator D5G00_22615 ENOG4105CNA YD repeat protein D5G00_22655 ENOG4105CS6 Rhs element vgr protein D5G00_22735 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit D5G00_22775 ENOG4108JDX DNA polymerase iii, epsilon subunit D5G00_22785 ENOG4105D1A Methyltransferase D5G00_22795 ENOG4105E9H Lytic Murein transglycosylase D5G00_22800 ENOG4105F2W methyltransferase D5G00_22810 ENOG4105F27 Major Facilitator D5G00_22815 ENOG4105HEI LysR family (Transcriptional regulator D5G00_22820 ENOG4105CV8 reductase D5G00_22855 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase D5G00_22860 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) D5G00_22865 ENOG4108UMI ABC transporter, permease D5G00_22870 ENOG4105D01 (LipO)protein D5G00_22875 ENOG4108R8X outer membrane lipoprotein D5G00_22880 ENOG4108R96 Methyltransferase, YaeB family D5G00_22890 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion D5G00_22895 ENOG4108YZN class I peptide chain release factor D5G00_22900 ENOG4108VWS Yaeq family D5G00_22910 ENOG4105M1T rho-binding antiterminator D5G00_22920 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase D5G00_22925 ENOG4105CXN decarboxylase D5G00_22930 ENOG4108M1A Chitin-binding protein D5G00_22940 ENOG4105C0B DNA polymerase III (alpha subunit) D5G00_22985 ENOG4105KNE Phosphatidate cytidylyltransferase D5G00_23025 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) D5G00_23040 ENOG4105DMJ Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity) D5G00_23050 ENOG4105CSH Transporter D5G00_23065 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR D5G00_23070 ENOG4105C0H protease D5G00_23085 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) D5G00_23090 ENOG4105EN6 Membrane D5G00_23110 ENOG4106RDH Protein of unknown function (DUF2544) D5G00_23120 ENOG4105UGQ Fimbrial D5G00_23125 ENOG4105NEV Fimbrial D5G00_23130 ENOG4108FZ9 Chaperone D5G00_23135 ENOG4106PG1 outer membrane usher protein D5G00_23150 ENOG4105S6R Iron-hydroxamate transporter permease subunit D5G00_23155 ENOG4105J76 Periplasmic binding protein D5G00_23160 ENOG4105E0A ABC, transporter D5G00_23165 ENOG4105E0K tonB-dependent siderophore receptor D5G00_23170 ENOG4105BZ4 penicillin-binding protein D5G00_23175 ENOG4105CQ7 ATP-dependent helicase D5G00_23180 ENOG4107XID 2'-5' rna ligase D5G00_23190 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters D5G00_23195 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) D5G00_23200 ENOG4105DJ0 Poly(A) Polymerase D5G00_23205 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase D5G00_23225 ENOG4107BJW polysaccharide deacetylase D5G00_23230 ENOG4108YTN IIa component D5G00_23240 ENOG4108UIF Chaperone D5G00_23245 ENOG4105CW0 outer membrane usher protein D5G00_23250 ENOG4108MDY Fimbrial D5G00_23255 ENOG4105E3A (ABC) transporter D5G00_23260 ENOG4105DA5 (ABC) transporter D5G00_23265 ENOG41077A9 carbonic anhydrase D5G00_23270 ENOG4108UGV hypoxanthine phosphoribosyltransferase D5G00_23275 ENOG4105DZG Dehydrogenase D5G00_23280 ENOG4105E3B Multicopper oxidase D5G00_23285 ENOG4108ZRK uncharacterized protein yacC D5G00_23300 ENOG4105MVE transcriptional regulator D5G00_23305 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) D5G00_23310 ENOG4107S2N Type III effector Hrp-dependent D5G00_23315 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) D5G00_23330 ENOG4106HGK Inner membrane protein yieI D5G00_23335 ENOG4107QIJ Aconitate hydratase 2 D5G00_23345 ENOG4108NST exported protein D5G00_23360 ENOG4107QN2 dihydrolipoyl dehydrogenase D5G00_23365 ENOG4107QSN dihydrolipoamide acetyltransferase D5G00_23370 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) D5G00_23375 ENOG41073TP transcriptional regulator D5G00_23380 ENOG4105C85 amino acid D5G00_23385 ENOG4105CT4 transporter D5G00_23390 ENOG4105CUK Alpha-N-arabinofuranosidase (EC 3.2.1.55) D5G00_23395 ENOG4106A72 regulatory protein AmpE D5G00_23405 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase D5G00_23415 ENOG4108ZUW Major pilin subunit D5G00_23420 ENOG4107QHF type ii secretion system protein e D5G00_23425 ENOG4105D7Q type ii secretion system D5G00_23435 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) D5G00_23450 ENOG410642W LysR family Transcriptional regulator D5G00_23455 ENOG4108FN7 Aldo keto reductase D5G00_23460 ENOG4105M6F mutator MutT protein D5G00_23470 ENOG4108SR7 Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity) D5G00_23480 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) D5G00_23485 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) D5G00_23490 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) D5G00_23495 ENOG4105CPF Cell wall formation (By similarity) D5G00_23510 ENOG4105CNI cell division protein FtsW D5G00_23515 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) D5G00_23525 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) D5G00_23530 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) D5G00_23535 ENOG4105CJN penicillin-binding protein D5G00_23540 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) D5G00_23555 ENOG4107B7Y DNA-binding transcriptional regulator FruR D5G00_23560 ENOG4108ZP8 Acetolactate synthase small subunit D5G00_23565 ENOG4105C7K acetolactate synthase D5G00_23570 ENOG41064T2 transcriptional regulator, lysR family D5G00_23615 ENOG4105DP9 ABC transporter D5G00_23625 ENOG4105EQR Transposase IS116 IS110 IS902 D5G00_23635 ENOG4107T0D ABC, transporter D5G00_23640 ENOG4108KF1 Membrane D5G00_23645 ENOG41063TF transcriptional regulator (AraC D5G00_23660 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase D5G00_23680 ENOG4105CQ2 DNA polymerase D5G00_23690 ENOG4105D3G Pseudouridine synthase D5G00_23700 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) D5G00_23710 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) D5G00_23750 ENOG4105M5B (LipO)protein D5G00_23755 ENOG4105C54 Major Facilitator superfamily D5G00_23760 ENOG4105WQV ferredoxin-like protein D5G00_23765 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase D5G00_23815 ENOG4108XNW Transcriptional activatory protein CaiF D5G00_23820 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain D5G00_23825 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain D5G00_23850 ENOG4105CHY citrate lyase, alpha D5G00_23855 ENOG4105CI0 Citrate lyase D5G00_23865 ENOG4105DUA (citrate (pro-3S)-lyase ligase D5G00_23875 ENOG4106AFN Lyase and sodium transporter (By similarity) D5G00_23880 ENOG4107QSA Oxaloacetate decarboxylase D5G00_23885 ENOG4105D9Q decarboxylase (Beta subunit) D5G00_23890 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism D5G00_23895 ENOG4106YYS transcriptional regulatory protein D5G00_23915 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase D5G00_23930 ENOG4105DTN riboflavin biosynthesis protein ribF D5G00_23935 ENOG410647N response to DNA damage stimulus D5G00_23955 ENOG41063Z6 transcriptional regulator, lysR family D5G00_23975 ENOG4105C4X radical SAM domain protein D5G00_23980 ENOG41061MV Arylsulfatase D5G00_23990 ENOG4105CGH 5'-nucleotidase D5G00_24005 ENOG4105DQS Transcriptional regulator D5G00_24025 ENOG4106PH7 chaperone D5G00_24040 ENOG4105MHR Fimbrial protein D5G00_24045 ENOG4105CW0 outer membrane usher protein D5G00_24050 ENOG4108AF8 Chaperone D5G00_24110 ENOG4108QUJ UPF0174 protein YaaW D5G00_24115 ENOG4106HK8 GPR1 FUN34 yaaH family protein D5G00_24120 ENOG4108RIR Molybdenum cofactor biosynthesis protein D5G00_24130 ENOG4105BZG amino acid carrier protein D5G00_24140 ENOG4105D98 threonine synthase D5G00_24150 ENOG4105CFH Aspartokinase D5G00_24160 ENOG4106FVC RNA methyltransferase D5G00_24165 ENOG410759A D5G00_24170 ENOG41065U4 response regulator D5G00_24180 ENOG4108PNB DNA-binding transcriptional regulator D5G00_24190 ENOG4108VCD Chaperone D5G00_24195 ENOG4105CW0 outer membrane usher protein D5G00_24215 ENOG4105EB3 Histidine kinase D5G00_24220 ENOG4105E3W Two component transcriptional regulator (Winged helix family D5G00_24225 ENOG4108RH0 Crea protein D5G00_24230 ENOG4105UEI Transcriptional Regulator AraC Family D5G00_24250 ENOG4107SC1 transglycosylase D5G00_24255 ENOG4105C5H ABC transporter D5G00_24260 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase D5G00_24265 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) D5G00_24270 ENOG4105EAC phosphoserine phosphatase D5G00_24280 ENOG41062Z9 Membrane D5G00_24290 ENOG4105EUP HipA domain protein D5G00_24315 ENOG4105G0K glycine radical enzyme YjjI family D5G00_24320 ENOG41076CZ activating enzyme D5G00_24325 ENOG4105EYA deoxyribonuclease D5G00_24330 ENOG4108NRW Phospholipase, patatin family D5G00_24340 ENOG4105K3G Periplasmic Protein D5G00_24350 ENOG4105PAD Hydrolase D5G00_24355 ENOG4105KEG ribosomal-protein-alanine acetyltransferase D5G00_24360 ENOG4108WPU DNA polymerase III subunit psi D5G00_24385 ENOG4105YBH Protein of unknown function (DUF1435) D5G00_24390 ENOG4105BZU Histidine kinase D5G00_24395 ENOG4108819 ferric iron reductase D5G00_24400 ENOG4108UIN ybak prolyl-trna synthetase associated region D5G00_24405 ENOG4108T94 DNA-binding transcriptional activator BglJ D5G00_24410 ENOG4108N8T regulatoR D5G00_24415 ENOG4105DWK Membrane D5G00_24430 ENOG4106CVF DNA replication protein D5G00_24435 ENOG4105RI1 glycoprotein receptor D5G00_24445 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) D5G00_24450 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) D5G00_24455 ENOG4105F3R pts system mannose fructose sorbose family iid D5G00_24460 ENOG4105ETZ PTS System D5G00_24465 ENOG4108IQ3 PTS system D5G00_24480 ENOG4105C8Q Methyl-accepting chemotaxis D5G00_24485 ENOG4105D22 carbon starvation protein D5G00_24490 ENOG4105VCD cytoplasmic protein D5G00_24495 ENOG4105CKI cobalamin synthesis protein D5G00_24535 ENOG4105CVR type I restriction-modification system D5G00_24545 ENOG4105DZR Type I site-specific deoxyribonuclease D5G00_24550 ENOG4108HFV D5G00_24565 ENOG4105C26 Dehydrogenase D5G00_24575 ENOG41083G8 Multidrug resistance protein MdtM D5G00_24580 ENOG4106BRA Membrane D5G00_24585 ENOG4105CBP Major Facilitator D5G00_24595 ENOG41074DU domain protein D5G00_24600 ENOG4108P2H Inner membrane protein YjiG D5G00_24605 ENOG4105DYB Isoaspartyl dipeptidase D5G00_24610 ENOG4107YNJ LysR family Transcriptional regulator D5G00_24630 ENOG4105C6F GntR Family Transcriptional Regulator D5G00_24655 ENOG4105KZM cytoplasmic protein D5G00_24675 ENOG4105DTA methyltransferase D5G00_24685 ENOG4105CDY transcriptional regulatory protein D5G00_24790 ENOG4105DQ4 alcohol dehydrogenase D5G00_24795 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family D5G00_24800 ENOG4105CPQ Dehydrogenase D5G00_24805 ENOG4105CHR reductase D5G00_24810 ENOG4105C6Z Gluconate D5G00_24815 ENOG4105K2J Transcriptional regulator D5G00_24820 ENOG4108K5H permease YjgP YjgQ family protein D5G00_24825 ENOG4108M8S permease YjgP YjgQ family protein D5G00_24845 ENOG4105MYG DNA polymerase iii, chi subunit D5G00_24850 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) D5G00_24860 ENOG4108MJ3 acetyltransferase D5G00_24865 ENOG4105EQR Transposase IS116 IS110 IS902 D5G00_24875 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase D5G00_24880 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) D5G00_24885 ENOG4105DBV ornithine carbamoyltransferase D5G00_24890 ENOG4105XEP YhcH YjgK YiaL family protein D5G00_24905 ENOG4105C5B carbamate kinase D5G00_24940 ENOG4107CBI conjugal transfer fertility inhibition protein D5G00_24955 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) D5G00_24970 ENOG4106CQM replication D5G00_24985 ENOG4108YXQ IS66 Orf2 family protein D5G00_25060 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A D5G00_25070 ENOG4105XY2 plasmid maintenance protein CcdA D5G00_25075 ENOG4105PPN plasmid maintenance protein, CcdB D5G00_25150 ENOG4105K4U addiction module toxin, RelE StbE family D5G00_25205 ENOG4105MDZ Transcriptional activator rfaH D5G00_25255 ENOG4105CMA conjugation trbi family protein D5G00_25285 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) D5G00_25290 ENOG4105KF5 hemolysin expression-modulating protein D5G00_25330 ENOG4105K70 DNA-binding protein D5G00_25380 ENOG4105D07 Signal peptide peptidase, SppA D5G00_25425 ENOG410607W Transposase D5G00_25545 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) D5G00_25605 ENOG4105EQR Transposase IS116 IS110 IS902 D5G00_25645 ENOG4105BZU Histidine kinase D5G00_25720 ENOG4108FPN Integrase D5G00_25805 ENOG41073YN Protein of unknown function (DUF1380) D5G00_25840 ENOG4106JGA Chromosome (Plasmid) partitioning protein, ParB D5G00_25845 ENOG4105EZN Cobyrinic acid ac-diamide synthase D5G00_25860 ENOG4105PPN plasmid maintenance protein, CcdB D5G00_25865 ENOG4105XY2 plasmid maintenance protein CcdA D5G00_25895 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A D5G00_25900 ENOG4105DB4 D5G00_25910 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A D5G00_25915 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) D5G00_25930 ENOG410607W Transposase D5G00_26080 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) D5G00_26170 ENOG4105BZU Histidine kinase D5G00_26205 ENOG410607W Transposase D5G00_26280 ENOG4108R0M Aminoglycoside D5G00_26300 ENOG4107QJE Chromosome Partitioning Protein