locus-tag class description CS348_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) CS348_00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CS348_00035 ENOG410667J hydrolase CS348_00055 ENOG4105BZU Histidine kinase CS348_00060 ENOG4108SV3 Tmao reductase system periplasmic protein tort CS348_00065 ENOG4106WF9 DNA-binding transcriptional regulator TorR CS348_00070 ENOG4105CUW cytochrome C-TYPE protein CS348_00075 ENOG4108EM1 reductase CS348_00085 ENOG4105CA0 peroxidase CS348_00095 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) CS348_00100 ENOG41060IM Heme exporter protein CS348_00105 ENOG4105X3C heme exporter protein CS348_00110 ENOG4108ZKK Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity) CS348_00115 ENOG4105DA4 cytochrome c-type biogenesis protein CS348_00120 ENOG4107QX9 Thiol disulfide interChange protein CS348_00125 ENOG4105KWW Biogenesis protein CS348_00130 ENOG4105D99 atp gtp-binding protein CS348_00135 ENOG4105R2A (LipO)protein CS348_00155 ENOG4105VG5 Membrane CS348_00160 ENOG4105JP4 Inner membrane protein yidG CS348_00165 ENOG4105J13 transcriptional regulator CS348_00180 ENOG4105W8I Transcriptional regulator CS348_00190 ENOG4105E5M Multidrug resistance protein D CS348_00215 ENOG4105C7K acetolactate synthase CS348_00220 ENOG4105M71 acetolactate synthase 1 regulatory subunit CS348_00225 ENOG4107FB0 transcriptional regulator DeoR family CS348_00230 ENOG4108RVA ribokinase CS348_00235 ENOG4105EDR glucose galactose transporter CS348_00245 ENOG4108KX4 response regulator CS348_00250 ENOG4105BZU Histidine kinase CS348_00255 ENOG4105CXY transporter CS348_00260 ENOG4105CXY transporter CS348_00265 ENOG4108SAJ Protein of unknown function (DUF1198) CS348_00270 ENOG4105FDP GntR family transcriptional regulator CS348_00280 ENOG41090UW PTS System CS348_00285 ENOG4105DT3 PTS system, galactitol-specific IIc component CS348_00295 ENOG4105D2N Aldolase CS348_00325 ENOG4105CS2 ec 3.2.1.21 CS348_00345 ENOG4108EQA pts system CS348_00350 ENOG4105ETZ PTS System CS348_00355 ENOG4105F3R pts system mannose fructose sorbose family iid CS348_00370 ENOG4105DNE Transposase CS348_00375 ENOG4108UZ3 Transporter CS348_00385 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic CS348_00405 ENOG4105CHJ isochorismatase hydrolase CS348_00415 ENOG4108TC1 Transcriptional regulator CS348_00420 ENOG4105FV3 CS348_00430 ENOG4105ISV protein with bipartite regulator domain CS348_00465 ENOG4105CT4 transporter CS348_00470 ENOG4105CJQ hydrolase, family 31 CS348_00475 ENOG4105JV1 AsmA family CS348_00480 ENOG4105C2W permease CS348_00485 ENOG4105D6U Sodium Glutamate Symporter CS348_00490 ENOG4105CB5 ATP-dependent DNA helicase recG CS348_00495 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase CS348_00500 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) CS348_00505 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) CS348_00520 ENOG4105EN6 Membrane CS348_00530 ENOG4108PZW LysR family Transcriptional regulator CS348_00535 ENOG4105DSJ YicC domain protein CS348_00565 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase CS348_00580 ENOG4105W0E 50S ribosomal protein L33 CS348_00595 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase CS348_00600 ENOG4105DKP glycosyl transferase, family 9 CS348_00605 ENOG4107RJ7 Glycosyl transferase (Group 1 CS348_00610 ENOG4107543 (lipo)polysaccharide CS348_00615 ENOG4105P7J Transfers sialic acid from the substrate CMP-sialic acid donor to the terminal beta-D-galactosyl-1,4-acetyl-beta-D- glucosamine on the lacto-N-neotetraose branch of the lipooligosaccharide CS348_00620 ENOG4107XU6 Glycosyl transferase (Group 1 CS348_00625 ENOG4106AH0 Glycosyl Transferase CS348_00630 ENOG4105X1N Glycosyl transferase family 8 CS348_00635 ENOG4108PDR lipopolysaccharide core biosynthesis protein CS348_00640 ENOG4108QD8 lipopolysaccharide core biosynthesis protein CS348_00645 ENOG4107XB0 Lipopolysaccharide 1,2-N-acetylglucosaminetransferase CS348_00650 ENOG4108FRV O-antigen ligase CS348_00655 ENOG4105D16 lipopolysaccharide heptosyltransferase i CS348_00660 ENOG4105XA0 heptosyltransferase ii CS348_00670 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) CS348_00680 ENOG4105K64 Glycosyl transferase, family 2 CS348_00685 ENOG4105PXI polysaccharide deacetylase CS348_00690 ENOG41063SB peptidase CS348_00700 ENOG4107YZP Rhodanese domain protein CS348_00705 ENOG4105VW4 glutaredoxin 3 CS348_00720 ENOG4105D7W serine acetyltransferase CS348_00725 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) CS348_00735 ENOG41073TP transcriptional regulator CS348_00740 ENOG4105DAA L-lactate CS348_00745 ENOG4105EUR Domain-Containing protein CS348_00750 ENOG4108WY4 inner membrane lipoprotein CS348_00760 ENOG4108YYI Protein of unknown function (DUF2810) CS348_00770 ENOG4105E61 Mannitol repressor protein CS348_00780 ENOG4105CTS PTS system mannitol-specific CS348_00785 ENOG4108U78 Glutathione S-transferase CS348_00795 ENOG4105EM7 Selenocysteine-specific translation elongation factor CS348_00800 ENOG4105C0A alcohol dehydrogenase CS348_00805 ENOG41066F8 ROK family CS348_00810 ENOG4105C26 Dehydrogenase CS348_00825 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase CS348_00830 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase CS348_00835 ENOG4105H6Q decarboxylase CS348_00840 ENOG4105CMG Carbohydrate kinase CS348_00845 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit CS348_00850 ENOG4105CG6 trap dicarboxylate transporter dctm subunit CS348_00855 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter CS348_00860 ENOG4108M5W CS348_00865 ENOG4108R66 Conserved Protein CS348_00875 ENOG4105J4Q Transcriptional regulator CS348_00880 ENOG4108XIB electron transport protein ysaA CS348_00885 ENOG4105JKW Valine--pyruvate aminotransferase CS348_00890 ENOG4107T9C Alpha amylase catalytic region CS348_00895 ENOG4108UR8 BAX protein CS348_00900 ENOG4105T16 Transcriptional regulator (AraC family) CS348_00915 ENOG4105CMG Carbohydrate kinase CS348_00920 ENOG410688U Inner membrane protein yiaB CS348_00925 ENOG4105MEV Acyl-transferase CS348_00935 ENOG4105RGS lipoprotein ysaB CS348_00950 ENOG4105DQ6 Transposase CS348_00990 ENOG4105VEQ Cold shock protein CS348_00995 ENOG4105MVF Transcriptional regulator CS348_01000 ENOG4106JH6 (LipO)protein CS348_01010 ENOG4108ZG0 Ompa motb domain protein CS348_01015 ENOG4107QY8 reductase CS348_01020 ENOG4105HNP -acetyltransferase CS348_01025 ENOG4108R3E Dna-3-methyladenine glycosylase i CS348_01030 ENOG4105EAX Putative lipase CS348_01035 ENOG4105DIJ Phosphoethanolamine transferase CS348_01070 ENOG4105DEF Extracellular solute-binding protein, family 5 CS348_01075 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CS348_01080 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CS348_01085 ENOG4105C3U ABC transporter CS348_01090 ENOG4108JQ7 (ABC) transporter CS348_01095 ENOG4105C44 Serine transporter CS348_01110 ENOG4105D1V cellulose synthase operon protein YhjU CS348_01115 ENOG410675P Celllulose biosynthesis operon protein BcsF YhjT CS348_01125 ENOG410661M cytoplasmic protein CS348_01130 ENOG4105UTS cellulose synthase operon protein YhjQ CS348_01135 ENOG4107QZ7 Cellulose synthase catalytic subunit CS348_01140 ENOG4107EEX Cellulose synthase regulator protein CS348_01145 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) CS348_01150 ENOG4105EJG cellulose synthase CS348_01160 ENOG4105BZU Histidine kinase CS348_01170 ENOG4105CS0 peptidase CS348_01175 ENOG4107SS6 2-dehydro-3-deoxygluconokinase CS348_01180 ENOG4105CMB EAL domain-containing protein CS348_01185 ENOG41066T0 asmA family CS348_01190 ENOG4105CSH Transporter CS348_01195 ENOG4107H3J ribonuclease CS348_01200 ENOG4105CBN LysR family transcriptional regulator CS348_01205 ENOG4106S2D Transcriptional regulator CS348_01225 ENOG4105FDP GntR family transcriptional regulator CS348_01230 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine CS348_01235 ENOG4108KPW sugar kinase CS348_01240 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CS348_01250 ENOG4105DC8 reductase CS348_01255 ENOG4105D6S protein involved in catabolism of external DNA CS348_01260 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase CS348_01265 ENOG4105DGW oligopeptidase A CS348_01275 ENOG4105DUX Transporter CS348_01280 ENOG4108M6U Universal stress protein A CS348_01290 ENOG4105CJ3 phosphate transporter CS348_01295 ENOG4105CBX hi0933 family CS348_01300 ENOG4105D0S secretion protein (HlyD CS348_01305 ENOG4105CJ1 ABC, transporter CS348_01310 ENOG4105CMI transporter CS348_01320 ENOG4107YAK holo-(acyl carrier protein) synthase 2 CS348_01325 ENOG4105DSF transport protein CS348_01335 ENOG4108W1V Lipoprotein CS348_01340 ENOG4105EX9 Membrane CS348_01350 ENOG4105C8Q Methyl-accepting chemotaxis CS348_01360 ENOG4107FS9 Membrane CS348_01370 ENOG4105MG3 Membrane CS348_01375 ENOG4106H78 methyltransferase CS348_01380 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) CS348_01385 ENOG4105CAK Cell division ATP-binding protein ftsE CS348_01390 ENOG4105CRP Part of the ABC transporter FtsEX involved in CS348_01400 ENOG4105CP9 extracellular ligand-binding receptor CS348_01410 ENOG4105U59 -acetyltransferase CS348_01415 ENOG4105CP9 extracellular ligand-binding receptor CS348_01420 ENOG4105C32 Amino acid ABC transporter (Permease) CS348_01425 ENOG4105CF8 branched-chain amino acid ABC transporter, permease CS348_01430 ENOG4105C0Z ABC transporter CS348_01435 ENOG4108IV0 ABC, transporter CS348_01440 ENOG41060M8 Pfam:PhdYeFM CS348_01450 ENOG4105BZ7 extracellular solute-binding protein family 1 CS348_01470 ENOG4107T6V glycerophosphoryl diester phosphodiesterase CS348_01475 ENOG4105WC8 Conserved Protein CS348_01480 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) CS348_01485 ENOG41080QX K07048 phosphotriesterase-related protein CS348_01500 ENOG4108RVA ribokinase CS348_01505 ENOG4105WCN acetyltransferase CS348_01515 ENOG4105D9R oxidoreductase CS348_01520 ENOG4105C2I pirin domain protein CS348_01525 ENOG4105DIQ Transcriptional regulator CS348_01530 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family CS348_01535 ENOG4105C6Z Gluconate CS348_01545 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) CS348_01550 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) CS348_01570 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) CS348_01575 ENOG4105C6V Glycerol-3-phosphate dehydrogenase CS348_01590 ENOG4105E98 transcriptional regulator DeoR family CS348_01600 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) CS348_01605 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) CS348_01610 ENOG4105C6Z Gluconate CS348_01620 ENOG4105MJ2 Competence protein CS348_01630 ENOG4105DNE Transposase CS348_01640 ENOG4105CE1 Ferrous iron transport protein b CS348_01645 ENOG4105XFK Ferrous iron transport protein A CS348_01655 ENOG4105BZM domain protein CS348_01660 ENOG4108RRZ Transcription elongation factor GreB CS348_01665 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CS348_01670 ENOG4105E0F Histidine kinase CS348_01680 ENOG4108MAJ Membrane CS348_01690 ENOG4105VEJ Heat shock protein CS348_01695 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 CS348_01700 ENOG4105DQY intracellular growth attenuator CS348_01705 ENOG4107RK2 ADP-ribose diphosphatase NudE CS348_01710 ENOG4108JQC penicillin-binding protein 1A CS348_01715 ENOG4108U1Q Pilus assembly protein CS348_01720 ENOG41065NF Fimbrial assembly family protein CS348_01725 ENOG4105XPX DNA utilization protein HofO CS348_01730 ENOG4105ITY Required for the use of extracellular DNA as a nutrient CS348_01735 ENOG4105E4G Type IV pilus CS348_01760 ENOG4105EGB membrane protein DamX CS348_01765 ENOG4105DFE Dna adenine methylase CS348_01770 ENOG4105DJV ribulose-phosphate 3-epimerase CS348_01780 ENOG4105C31 Tryptophanyl-tRNA synthetase CS348_01785 ENOG4105VYH CS348_01790 ENOG4107EF2 surface-exposed virulence protein CS348_01800 ENOG4107V9H nitrite transporter CS348_01805 ENOG4105WZK nitrite reductase NADPH small subunit CS348_01810 ENOG4107QZF nitrite reductase NADPH large subunit CS348_01820 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) CS348_01825 ENOG4106195 uncharacterized protein yhfG CS348_01830 ENOG4105MZU cell filamentation protein CS348_01835 ENOG4105DDQ anthranilate synthase CS348_01840 ENOG4105C8Y Acetylornithine aminotransferase CS348_01845 ENOG410613R integral membrane protein, YccS YhfK family CS348_01855 ENOG4108UKZ OsmC family CS348_01860 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) CS348_01870 ENOG4105DNZ Alpha Beta Hydrolase CS348_01875 ENOG4105N0V mono-oxygenase ydhR CS348_01880 ENOG4108K70 Transcriptional regulator CS348_01885 ENOG4105C5H ABC transporter CS348_01900 ENOG4105VKU nucleicacid-binding protein CS348_01905 ENOG4108YZY peptidylprolyl cis-trans isomerase CS348_01915 ENOG4108V1T peptidylprolyl cis-trans isomerase CS348_01925 ENOG4108RS6 transposase CS348_01935 ENOG4105WWK YheO domain protein CS348_01950 ENOG4105YKK Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) CS348_01960 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) CS348_01970 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) CS348_01985 ENOG4105W53 bacterioferritin-associated ferredoxin CS348_01990 ENOG4108UQY Iron-storage protein CS348_01995 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) CS348_02015 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) CS348_02030 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) CS348_02035 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) CS348_02040 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) CS348_02050 ENOG41083MP 50s ribosomal protein l29 CS348_02060 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) CS348_02065 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) CS348_02080 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) CS348_02090 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) CS348_02095 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) CS348_02100 ENOG4105VPB 50S ribosomal protein L30 CS348_02105 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) CS348_02110 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) CS348_02115 ENOG41067V7 50S ribosomal protein L36 CS348_02135 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) CS348_02145 ENOG4105VTS DnaJ-like, subfamily C CS348_02150 ENOG4105W1Y Transcriptional regulator CS348_02155 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system CS348_02165 ENOG4105C1A potassium transporter peripheral membrane CS348_02185 ENOG4105C79 DNA protecting protein DprA CS348_02195 ENOG4108WI1 Dna topoisomerase CS348_02210 ENOG4105SG3 Protein of unknown function (DUF1488) CS348_02215 ENOG4108Z0R Transferase CS348_02250 ENOG4105XCM membrane LIPOPROTEIN CS348_02255 ENOG4105BZS acriflavin resistance protein CS348_02260 ENOG4105C1P efflux transporter, rnd family, mfp subunit CS348_02265 ENOG4108XG4 DNA-binding transcriptional regulator CS348_02270 ENOG4105BZU Histidine kinase CS348_02275 ENOG41061ME transport protein CS348_02280 ENOG4105CEC DNA methylase N-4 N-6 CS348_02285 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) CS348_02290 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) CS348_02305 ENOG4108IA2 Sodium pantothenate symporter CS348_02310 ENOG4105RG0 Membrane CS348_02315 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase CS348_02320 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein CS348_02335 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family CS348_02340 ENOG41062P1 Diguanylate cyclase phosphodiesterase CS348_02355 ENOG4105DFF Rod shape-determining protein mreb CS348_02360 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) CS348_02365 ENOG4105VQ7 Rod shape-determining protein MreD CS348_02375 ENOG4105C03 ribonuclease CS348_02380 ENOG4105QD6 exported protein CS348_02385 ENOG4105D1U peptidase U62 modulator of DNA gyrase CS348_02390 ENOG4105CR8 Transcriptional regulator CS348_02395 ENOG4105ZQC membrane protein AaeX CS348_02410 ENOG4105UNR (Barnase) inhibitor CS348_02415 ENOG4105RID UPF0379 protein yhcN CS348_02420 ENOG4105RID UPF0379 protein yhcN CS348_02435 ENOG4105FDP GntR family transcriptional regulator CS348_02445 ENOG4105C8P )-transporter CS348_02450 ENOG4106DSS Tartrate dehydratase subunit alpha CS348_02455 ENOG4107GFK fumarate CS348_02465 ENOG4107QSA Oxaloacetate decarboxylase CS348_02470 ENOG4105D9Q decarboxylase (Beta subunit) CS348_02485 ENOG4105C0H protease CS348_02490 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III CS348_02495 ENOG4105D6Z AFG1 family ATPase CS348_02515 ENOG4107MKT Stringent starvation protein a CS348_02520 ENOG4105KB2 stringent starvation protein b CS348_02550 ENOG4108R66 Conserved Protein CS348_02555 ENOG4105DZC cytosine deaminase CS348_02560 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin CS348_02565 ENOG4105DFS Conserved Protein CS348_02570 ENOG4105BZ8 glutamate synthase CS348_02575 ENOG4105CBC glutamate synthase CS348_02585 ENOG4105N5T Radical SAM Protein CS348_02590 ENOG4105BZU Histidine kinase CS348_02595 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain CS348_02605 ENOG4108NIH transferase activity, transferring phosphorus-containing groups CS348_02615 ENOG41080Z8 PHOSPHOCARRIER protein CS348_02625 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN CS348_02630 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA CS348_02635 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CS348_02640 ENOG4108IUZ ABC transporter CS348_02645 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA CS348_02650 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) CS348_02655 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase CS348_02660 ENOG4105C2X Arabinose 5-phosphate isomerase CS348_02665 ENOG4105FEU K -dependent Na -Ca exchanger CS348_02670 ENOG4105DHJ ABC, transporter CS348_02675 ENOG4105CY3 ABC transporter, permease CS348_02680 ENOG4107PE3 Mammalian cell entry related domain protein CS348_02685 ENOG4105E3I toluene tolerance CS348_02690 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane CS348_02695 ENOG4105VFK BolA family CS348_02705 ENOG4105HVQ Regulatory factor of maltose metabolism CS348_02710 ENOG4105EAH synthase CS348_02725 ENOG4105QYV Membrane CS348_02735 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase CS348_02740 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) CS348_02745 ENOG4105HBR Rna-binding protein CS348_02750 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) CS348_02760 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) CS348_02765 ENOG4105EEI dihydropteroate synthase CS348_02805 ENOG4105CHV Transcription elongation factor NusA CS348_02840 ENOG4105C1J atp-dependent rna helicase CS348_02845 ENOG4105CIC tryptophan-specific transport protein CS348_02850 ENOG4105DEN Luciferase family CS348_02855 ENOG4106RZ4 Peptidase U32 CS348_02860 ENOG4105CFP Peptidase U32 CS348_02865 ENOG4105XPQ lipid carrier protein CS348_02870 ENOG4108YYD acetyltransferase CS348_02885 ENOG4107R7Y intracellular protease Pfpi family CS348_02890 ENOG4105K4T epimerase CS348_02895 ENOG4105W4M Transport-associated protein CS348_02915 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) CS348_02925 ENOG4107WTH Galactitol-1-phosphate dehydrogenase CS348_02930 ENOG4105DT3 PTS system, galactitol-specific IIc component CS348_02935 ENOG41090UW PTS System CS348_02940 ENOG41082GB PTS system galactitol-specific transporter subunit IIA CS348_02955 ENOG4105CTX dehydratase CS348_02965 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase CS348_02970 ENOG4105BZW Glycerate kinase CS348_02995 ENOG410811B TRANSCRIPTIONal CS348_03000 ENOG4105C7B Threonine dehydratase CS348_03015 ENOG4105C6N Formate acetyltransferase CS348_03020 ENOG4105EJQ L-serine dehydratase CS348_03025 ENOG4105C44 Serine transporter CS348_03035 ENOG4106D80 Uncharacterized protein YhaL CS348_03040 ENOG4108CNN domain protein CS348_03045 ENOG4105CWB LysR family transcriptional Regulator CS348_03050 ENOG4105KAF membrAne CS348_03055 ENOG4105CHF Glutathione S-transferase CS348_03060 ENOG4108VBZ doxx family CS348_03065 ENOG4105YJD CS348_03070 ENOG41090KG Inner membrane protein YqjE CS348_03075 ENOG4105NE1 Conserved Protein CS348_03080 ENOG4105WAY exported protein CS348_03090 ENOG4106W5V Membrane CS348_03105 ENOG4105DU1 integral membrane protein, terc CS348_03110 ENOG4105EE0 oxidoreductase CS348_03115 ENOG4108UB4 uncharacterized protein ygjQ CS348_03120 ENOG4108VKG metal-dependent hydrolase CS348_03130 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase CS348_03145 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor CS348_03150 ENOG4105C8Q Methyl-accepting chemotaxis CS348_03155 ENOG4105NTW Transcriptional regulator CS348_03160 ENOG4105Q26 Siderophore-interacting protein CS348_03175 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CS348_03180 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) CS348_03185 ENOG4105VCC 30S ribosomal protein S21 CS348_03195 ENOG4106DSS Tartrate dehydratase subunit alpha CS348_03205 ENOG4107ZVW dihydroneopterin aldolase CS348_03220 ENOG4106MWK domain protein CS348_03225 ENOG4105I7R Adenylate cyclase CS348_03245 ENOG4107S78 Band 7 protein CS348_03260 ENOG4105W0Z cytoplasmic protein CS348_03280 ENOG4108MR7 Arylsulfotransferase CS348_03295 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b CS348_03300 ENOG4106032 Glutathionylspermidine synthase CS348_03320 ENOG41087AY ADP-Ribose pyrophosphatase CS348_03325 ENOG4108SX3 cytoplasmic protein CS348_03330 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) CS348_03335 ENOG4105IPS esterase CS348_03340 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CS348_03345 ENOG4105VRH Antibiotic biosynthesis monooxygenase CS348_03350 ENOG4105NF4 modulator of drug activity CS348_03355 ENOG4105DHQ Histidine kinase CS348_03360 ENOG4105XJC Two component transcriptional regulator (Winged helix family CS348_03365 ENOG4105H4F exported protein CS348_03370 ENOG4105F4I Transcriptional regulator CS348_03375 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CS348_03380 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase CS348_03385 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) CS348_03410 ENOG4105CCT upf0313 protein CS348_03445 ENOG4105ZKC Conserved Protein CS348_03455 ENOG4107QPK )-transporter CS348_03460 ENOG4105CV8 reductase CS348_03465 ENOG4108I6A alcohol dehydrogenase CS348_03470 ENOG4105CF7 AraC family transcriptional regulator CS348_03475 ENOG4108K81 inner membrane protein YghB CS348_03480 ENOG4105C28 cystathionine CS348_03490 ENOG4105CWK Biopolymer transport protein, ExbB CS348_03495 ENOG4108ZZF transport protein (ExbD) CS348_03500 ENOG4105CYX Short-chain dehydrogenase reductase Sdr CS348_03525 ENOG4105C8Q Methyl-accepting chemotaxis CS348_03530 ENOG410900S Protein of unknown function (DUF2623) CS348_03540 ENOG4105E3S small subunit CS348_03545 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein CS348_03550 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit CS348_03555 ENOG4105DPX Hydrogenase, large subunit CS348_03560 ENOG4108USZ hydrogenase CS348_03565 ENOG4108WGS hydrogenase 2-specific chaperone CS348_03570 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) CS348_03575 ENOG41082MF Hydrogenase assembly chaperone hypC hupF CS348_03580 ENOG4105S10 periplasmic binding protein CS348_03585 ENOG4108VJC ABC transporter, periplasmic molybdate-binding protein CS348_03590 ENOG4105CYM Glutathione S-transferase CS348_03595 ENOG4106032 Glutathionylspermidine synthase CS348_03610 ENOG4105DEI Mannitol dehydrogenase CS348_03625 ENOG4105DPW Major facilitator superfamily MFS_1 CS348_03630 ENOG4108QNI outer membrane porin protein CS348_03635 ENOG4105CT4 transporter CS348_03640 ENOG4105CNT hydrolase family 2 CS348_03645 ENOG4105XEA Tetr family transcriptional regulator CS348_03670 ENOG4105C26 Dehydrogenase CS348_03675 ENOG4105CJP fad dependent oxidoreductase CS348_03685 ENOG4105CUB amino acid CS348_03695 ENOG4108UAJ Transcriptional regulator CS348_03705 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) CS348_03715 ENOG4105CI0 Citrate lyase CS348_03720 ENOG4105DJG MaoC domain protein dehydratase CS348_03725 ENOG4105CYC Transferase CS348_03730 ENOG4109025 Glyoxalase Bleomycin resistance protein (Dioxygenase CS348_03750 ENOG4105CDU Replicative dna helicase CS348_03760 ENOG4105KSC Transcriptional regulator, TraR DksA family CS348_03795 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) CS348_03810 ENOG4108UUM single-stranded DNA-binding protein CS348_03815 ENOG4105DNE Transposase CS348_03850 ENOG4107QHF type ii secretion system protein e CS348_03865 ENOG4105K5T PilT protein CS348_04085 ENOG4105BZV Phosphoadenosine phosphosulfate reductase CS348_04095 ENOG4105GTN ParB Domain Protein Nuclease CS348_04130 ENOG4105H8W Fimbrial protein CS348_04140 ENOG4108TTM chaperone CS348_04315 ENOG4105R9B Major Facilitator CS348_04320 ENOG4105KME endoribonuclease L-psp CS348_04330 ENOG4105WWK YheO domain protein CS348_04350 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation CS348_04370 ENOG4108UQV Membrane CS348_04380 ENOG4105CXN decarboxylase CS348_04385 ENOG4105EAA nucleoside CS348_04400 ENOG4105CEN a g-specific adenine glycosylase CS348_04415 ENOG41090ED Protein with unknown function (DUF469) CS348_04420 ENOG4105K33 Periplasmic Protein CS348_04425 ENOG4105HDK L-asparaginase CS348_04430 ENOG4106MH3 alpha helix chain CS348_04435 ENOG4105CSA Coproporphyrinogen iii oxidase CS348_04450 ENOG4108VIA integral membrane protein CS348_04455 ENOG4105DFA alanine racemase domain protein CS348_04460 ENOG4105CZX twitching motility protein CS348_04480 ENOG4105D7Z glutathione synthase CS348_04485 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) CS348_04490 ENOG4105RWS endonuclease I CS348_04500 ENOG4107QNK )-transporter CS348_04525 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) CS348_04535 ENOG4108K0D peptidase, M48 CS348_04540 ENOG4105CV1 Transketolase (EC 2.2.1.1) CS348_04545 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia CS348_04550 ENOG4105CTS PTS system mannitol-specific CS348_04555 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein CS348_04560 ENOG4108Q8A Fructose-1,6-bisphosphatase CS348_04565 ENOG4108R4K DNA-binding, transcriptional regulator CS348_04570 ENOG4107Z1W Fructose transport system kinase CS348_04575 ENOG4108JJB ABC transporter CS348_04580 ENOG4108JJB ABC transporter CS348_04615 ENOG4105D2N Aldolase CS348_04620 ENOG4105D64 Mechanosensitive ion channel CS348_04630 ENOG4105MPN Membrane CS348_04645 ENOG4108JQ1 Dehydrogenase CS348_04650 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase CS348_04675 ENOG4107RAQ aminopeptidase CS348_04680 ENOG4105D0A hydroxylase CS348_04685 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family CS348_04715 ENOG4105CS2 ec 3.2.1.21 CS348_04725 ENOG4108UT2 hemolysin iii CS348_04750 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB CS348_04755 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) CS348_04760 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CS348_04765 ENOG4105T95 Thiol disulfide interChange protein CS348_04770 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) CS348_04780 ENOG4105CRK lysyL-tRNA synthetase CS348_04795 ENOG4108K5P (LipO)protein CS348_04810 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A CS348_04825 ENOG4108T1M outer membrane protein x CS348_04845 ENOG4106P2F Pfam:Pili_assembly_C CS348_04875 ENOG4108MHD transport protein CS348_04885 ENOG4105C5Q Transcriptional regulator CS348_04890 ENOG4105CHU acetyl-coa acetyltransferase CS348_04905 ENOG4105CHR reductase CS348_04915 ENOG4107QNK )-transporter CS348_04925 ENOG4105RQF LysR family Transcriptional regulator CS348_04930 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) CS348_04935 ENOG4105DDV Transcriptional regulator (LacI family CS348_04950 ENOG4107S74 Lysophospholipid transporter LplT CS348_04955 ENOG4105CPC Aldo Keto reductase CS348_04960 ENOG4105SUV lipoprotein YgdR CS348_04965 ENOG4105EE5 Membrane protein terC CS348_04980 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase CS348_05000 ENOG4105IPU prepilin peptidase dependent protein A CS348_05005 ENOG4105JCS prepilin peptidase dependent protein CS348_05010 ENOG4105SEN Protein of unknown function (DUF2509) CS348_05015 ENOG4105RVB Prepilin peptidase dependent protein c CS348_05020 ENOG4105DSY exodeoxyribonuclease V, gamma CS348_05025 ENOG4107QXK peptidase CS348_05030 ENOG4107QKA exodeoxyribonuclease V beta CS348_05035 ENOG4107QYX exodeoxyribonuclease v alpha CS348_05040 ENOG4108EKC n-acetylglutamate synthase CS348_05045 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase CS348_05060 ENOG4105CA3 membrane-bound lytic murein transglycosylase CS348_05065 ENOG4105CUZ uba thif-type nad fad binding protein CS348_05070 ENOG4105FR1 rard protein CS348_05075 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) CS348_05080 ENOG4105C9B Cysteine desulfurase CS348_05085 ENOG4105M5B (LipO)protein CS348_05090 ENOG4105ETT transcriptional Regulator, LysR family CS348_05095 ENOG4105M08 Membrane CS348_05105 ENOG4107EDW L-fucose operon activator CS348_05115 ENOG4105CMG Carbohydrate kinase CS348_05125 ENOG4105EDR glucose galactose transporter CS348_05130 ENOG4107W7X Aldolase CS348_05135 ENOG4105C0A alcohol dehydrogenase CS348_05150 ENOG4105EJQ L-serine dehydratase CS348_05155 ENOG4105C44 Serine transporter CS348_05160 ENOG4105EWT decarboxylase family CS348_05180 ENOG4105WP7 tRNA pseudouridine synthase C CS348_05185 ENOG4105DR9 pseudouridine synthase CS348_05190 ENOG4105QDK Flavodoxin CS348_05200 ENOG4105DJB Major Facilitator Superfamily CS348_05205 ENOG4105EQX glucarate dehydratase CS348_05210 ENOG4105EQX glucarate dehydratase CS348_05215 ENOG4105BZW Glycerate kinase CS348_05220 ENOG4105BZU Histidine kinase CS348_05225 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) CS348_05230 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) CS348_05235 ENOG4105X54 addiction module antidote protein CS348_05250 ENOG4105DXN mazG family CS348_05265 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) CS348_05270 ENOG4108H5C Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) CS348_05275 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase CS348_05310 ENOG4105DTT CRISPR-associated helicase, cas3 CS348_05325 ENOG41060M0 Crispr-associated protein, cse4 family CS348_05330 ENOG4108VWQ crispr-associated protein CS348_05340 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) CS348_05345 ENOG4105PWE CRISPR-associated protein cas2 CS348_05350 ENOG4108MXK alkaline phosphatase isozyme conversion CS348_05370 ENOG4105N0Z inner membrane protein ygbE CS348_05405 ENOG4108K5P (LipO)protein CS348_05415 ENOG4105KZM cytoplasmic protein CS348_05420 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) CS348_05425 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase CS348_05435 ENOG4105MVE transcriptional regulator CS348_05445 ENOG4105G63 Type III effector Hrp-dependent CS348_05455 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) CS348_05460 ENOG4105EXW epimerase dehydratase CS348_05465 ENOG4105C6Z Gluconate CS348_05470 ENOG4105JQN Transcriptional regulator CS348_05475 ENOG4105C0R drug resistance transporter emrb qaca subfamily CS348_05495 ENOG4105MEW serine threonine protein phosphatase CS348_05525 ENOG41090HZ type iii secretion CS348_05530 ENOG4105K44 type iii secretion CS348_05535 ENOG4108N8R Invasion protein CS348_05540 ENOG4108HR8 type iii secretion CS348_05545 ENOG4105REY Chaperone specialized in the storage of effectors within the bacterial cytoplasm, maintaining them in a secretion-competent state, and allowing their immediate delivery to target cells upon contact of the bacterium with the host cells. Has been shown to chaperone CS348_05550 ENOG4108JIR Flagellum-specific ATP synthase CS348_05555 ENOG41077MC Secretory protein (Associated with virulence) CS348_05560 ENOG41078G4 surface presentation of CS348_05570 ENOG41075IY surface presentation of antigens protein SpaP CS348_05580 ENOG4108TN6 type iii secretion CS348_05585 ENOG4108M6W surface presentation of antigens protein SpaS CS348_05595 ENOG4106H1J Required for entry into the host cell through presentation or delivery of SipC at the host cell plasma membrane. Along with SipC, is necessary for the transfer of other effector proteins into the host cell. Induces macrophage apoptosis either by binding and activating the proapoptotic enzyme caspase-1 (caspase-1 dependent), resulting in the release of interleukin-1 beta active form, or by disrupting mitochondria and inducing autophagy (caspase-1 independent). The former is dependent of its membrane-fusion activity. The SipBC complex, in association with its chaperone SicA, is regulated by binding of InvE CS348_05605 ENOG4105IBT Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of SipA, SipB, and SipC CS348_05615 ENOG41079WB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) CS348_05630 ENOG410641W Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities. After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE. This function is independent of its tyrosine phosphatase activity, which remains unclear CS348_05635 ENOG4108J1Q CS348_05645 ENOG4108YAB Invasion protein CS348_05655 ENOG4108RC9 Type III secretion system protein CS348_05660 ENOG4105Y7Q type iii secretion CS348_05665 ENOG4106BTR CS348_05670 ENOG4108RBT type iii secretion CS348_05710 ENOG4105CC5 ABC transporter CS348_05715 ENOG4105CC5 ABC transporter CS348_05720 ENOG4105DIK (ABC) transporter CS348_05730 ENOG4105VXR cytoplasmic protein CS348_05740 ENOG4105C45 hydrogenase expression formation protein (HypE) CS348_05745 ENOG4105CQS hydrogenase expression formation protein HypD CS348_05750 ENOG41083WG hydrogenase assembly chaperone CS348_05755 ENOG4107RSS Hydrogenase accessory protein HypB CS348_05760 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) CS348_05775 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) CS348_05780 ENOG4107R30 NADH dehydrogenase CS348_05785 ENOG4107TDF Formate hydrogenlyase subunit 4 CS348_05790 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) CS348_05795 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit CS348_05800 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit CS348_05805 ENOG4105I6X formate hydrogenlyase maturation CS348_05810 ENOG4108MG9 hydrogenase 3 maturation protease CS348_05820 ENOG4108RC0 Electron transport protein CS348_05825 ENOG4105C8H hydrogenase maturation protein Hypf CS348_05845 ENOG4105C2X Arabinose 5-phosphate isomerase CS348_05850 ENOG410804X Transcriptional regulator CS348_05855 ENOG4105J92 DNA-binding transcriptional activator GutM CS348_05860 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase CS348_05865 ENOG4105VI0 Pts system, glucitol sorbitol-specific CS348_05870 ENOG4105DZY Pts system, glucitol sorbitol-specific CS348_05875 ENOG410787A Pts system, glucitol sorbitol-specific CS348_05880 ENOG4105CVE Lytic murein transglycosylase CS348_05890 ENOG4107TH8 cina domain protein CS348_05910 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) CS348_05915 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) CS348_05950 ENOG4107VXZ Hydrolase CS348_05955 ENOG4105W39 Membrane CS348_05975 ENOG4105C0R drug resistance transporter emrb qaca subfamily CS348_05980 ENOG4105CW7 secretion protein, HlyD family CS348_05985 ENOG4105NTK Transcriptional repressor Mpra CS348_05995 ENOG4105GIJ Glycine betaine CS348_06000 ENOG4108HQS Glycine betaine CS348_06005 ENOG4108IJ7 Glycine betaine CS348_06015 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CS348_06020 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CS348_06030 ENOG4105WAZ (Glutaredoxin-like protein) NrdH CS348_06040 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) CS348_06050 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) CS348_06055 ENOG4108WMJ Protein of unknown function (DUF2002) CS348_06060 ENOG4108RNS Exports L-alanine (By similarity) CS348_06080 ENOG4108X73 DNA- binding protein CS348_06090 ENOG4108V62 Rhodanese domain protein CS348_06095 ENOG41080HT Transcriptional regulator, arsr family CS348_06100 ENOG4105VPI YqaE family transport protein CS348_06110 ENOG4109066 lysm domain bon superfamily protein CS348_06115 ENOG4108PVQ transcriptional regulator CS348_06120 ENOG4105C85 amino acid CS348_06125 ENOG4108JPW Aminotransferase CS348_06130 ENOG4105C26 Dehydrogenase CS348_06135 ENOG4105D5U fad dependent oxidoreductase CS348_06165 ENOG4105DHQ Histidine kinase CS348_06185 ENOG4108MJ5 VirK protein CS348_06190 ENOG4105VRE Pentapeptide repeat protein CS348_06200 ENOG4107RNH Outer membrane receptor FepA CS348_06205 ENOG4105NIV Esterase CS348_06230 ENOG4105I03 Flagellin CS348_06330 ENOG4105DFP Integrase CS348_06345 ENOG4105BZ1 (ABC) transporter CS348_06365 ENOG4108Z1B Cyclase dehydrase CS348_06375 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) CS348_06380 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) CS348_06405 ENOG4108JU6 CBS domain protein CS348_06410 ENOG4106KVJ cytochrome C assembly protein CS348_06420 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY CS348_06445 ENOG4108KHX Diguanylate cyclase CS348_06450 ENOG4108WS1 CS348_06455 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) CS348_06460 ENOG4105EHE chorismate mutase- prephenate dehydrogenase CS348_06470 ENOG4105CQC Prephenate dehydratase CS348_06475 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA CS348_06480 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane CS348_06485 ENOG4105C34 Pseudouridine synthase CS348_06490 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase CS348_06495 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CS348_06525 ENOG4105CSH Transporter CS348_06530 ENOG4105T42 (LipO)protein CS348_06535 ENOG4105JIM Phosphatidylserine synthase CS348_06540 ENOG4105CD5 CoA-binding domain protein CS348_06545 ENOG4106IUH DTW domain containing protein CS348_06550 ENOG4105K63 Thioredoxin CS348_06560 ENOG4105EIB trna rrna methyltransferase CS348_06580 ENOG41090KR LysR family transcriptional Regulator CS348_06585 ENOG4105C1J atp-dependent rna helicase CS348_06595 ENOG4108IYU L-aspartate oxidase CS348_06620 ENOG4105WMJ Positive regulator of sigma E, RseC MucC CS348_06635 ENOG4105C3F Signal peptidase i CS348_06660 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) CS348_06670 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding CS348_06675 ENOG4105DND Transcriptional regulator CS348_06680 ENOG4105FCD Major Facilitator CS348_06685 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) CS348_06690 ENOG4106G6Q Transcriptional regulator CS348_06705 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB CS348_06710 ENOG4108Z6B deaminase CS348_06715 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) CS348_06725 ENOG4108ETH Formylglycinamide ribotide synthetase CS348_06730 ENOG4107WP9 Histidine kinase CS348_06735 ENOG4108SKK alpha helix protein CS348_06740 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CS348_06745 ENOG4108YZA Nitrogen regulatory protein pii CS348_06750 ENOG4105DUX Transporter CS348_06755 ENOG4105CXN decarboxylase CS348_06760 ENOG4105D5Q Arginine ornithine antiporter CS348_06765 ENOG4108M3R transcriptional activator CadC CS348_06780 ENOG4105D8G Major Facilitator superfamily CS348_06785 ENOG4108MN2 Stationary phase inducible protein CsiE CS348_06795 ENOG4105D7X high-affinity nickel-transporter CS348_06800 ENOG410810Y Sulfite reductase CS348_06805 ENOG4107SHJ sulfite reductase subunit b CS348_06810 ENOG4105D5B Sulfite reductase, subunit A CS348_06815 ENOG4107XM9 (LipO)protein CS348_06820 ENOG4105ECY inositol monophosphatase CS348_06840 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins CS348_06860 ENOG4108ZIT Ferredoxin, 2FE-2S CS348_06865 ENOG4105WVQ Fe-S assembly protein IscX CS348_06875 ENOG4105YYA enhanced serine sensitivity protein SseB CS348_06890 ENOG4105KHC sulfurtransferase CS348_06895 ENOG4105DN3 alpha-2-macroglobulin domain protein CS348_06900 ENOG4108JQB penicillin-binding protein 1C CS348_06905 ENOG4107QY8 reductase CS348_06910 ENOG4105QAX Iron-sulfur CS348_06930 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs CS348_06955 ENOG4105N21 Membrane CS348_06960 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) CS348_06970 ENOG4105VPD cellular component movement CS348_07005 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) CS348_07010 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) CS348_07035 ENOG41066DY Membrane CS348_07040 ENOG4108ZMA Outer membrane lipoprotein CS348_07045 ENOG41062G3 Protein of unknown function (DUF2633) CS348_07055 ENOG4105BZU Histidine kinase CS348_07060 ENOG4105C9X ppx gppa phosphatase CS348_07065 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) CS348_07070 ENOG4108V3E phosphoribosylglycinamide formyltransferase CS348_07085 ENOG4105C2W permease CS348_07095 ENOG4105K89 arsenate reductase CS348_07100 ENOG4105ERG peptidase m48, ste24p CS348_07105 ENOG4105C02 permease CS348_07110 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR CS348_07115 ENOG4107QQ0 gntp family CS348_07120 ENOG4105BZW Glycerate kinase CS348_07125 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen CS348_07130 ENOG4105RH4 Glycine cleavage system transcriptional repressor CS348_07140 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) CS348_07150 ENOG4105CGZ zinc metallopeptidase CS348_07155 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) CS348_07165 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) CS348_07170 ENOG4105KUZ arsenate reductase CS348_07175 ENOG4105BZS acriflavin resistance protein CS348_07180 ENOG4105BZU Histidine kinase CS348_07185 ENOG4105BZ8 glutamate synthase CS348_07200 ENOG4108PVD exported protein CS348_07210 ENOG4105CV1 Transketolase (EC 2.2.1.1) CS348_07215 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) CS348_07225 ENOG4105C6K Malic enzyme CS348_07230 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place CS348_07235 ENOG4106S4J ethanolamine utilization protein EutP CS348_07240 ENOG4105NDK ethanolamine utilization protein CS348_07245 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase CS348_07250 ENOG4108IJ2 phosphate acetyltransferase CS348_07255 ENOG4105KNY Microcompartments protein CS348_07260 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml CS348_07265 ENOG4108EKI Dehydrogenase CS348_07270 ENOG4107RWI ethanolamine utilization protein eutJ CS348_07275 ENOG4105C0A alcohol dehydrogenase CS348_07280 ENOG4105ENY Ethanolamine utilization protein eutH CS348_07285 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase CS348_07290 ENOG4105CPD ethanolamine ammonia-lyase CS348_07300 ENOG4106D67 ethanolamine utilization protein CS348_07305 ENOG4108X49 Ethanolamine utilization protein EutK CS348_07310 ENOG4108K3Z AraC family transcriptional regulator CS348_07320 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase CS348_07330 ENOG4105QZU Inner membrane protein YfeZ CS348_07335 ENOG4105E7K (LipO)protein CS348_07340 ENOG4105EZR dyp-type peroxidase family protein CS348_07345 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr CS348_07350 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein CS348_07355 ENOG4108I5D sulfate abc transporter CS348_07360 ENOG4105ECW sulfate abc transporter CS348_07365 ENOG4108IJ6 ABC transporter CS348_07370 ENOG4105C6T cysteine synthase CS348_07375 ENOG4105M0Y CS348_07380 ENOG41089BK Glutamine amido-transferase CS348_07385 ENOG4105CSW GntR family transcriptional regulator CS348_07400 ENOG4105C5Y PTS System CS348_07410 ENOG4105KZ7 phosphocarrier protein hpr CS348_07415 ENOG4105C6T cysteine synthase CS348_07440 ENOG4105VRT cytoplasmic protein CS348_07445 ENOG4105DHU Bile acid CS348_07450 ENOG4108M0I Transcriptional regulator CS348_07455 ENOG4108NFH Sugar hydrolase CS348_07460 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) CS348_07465 ENOG4105EAA nucleoside CS348_07475 ENOG4105CN8 Transcriptional regulator CS348_07500 ENOG4105GXM Putative transcription regulator (DUF1323) CS348_07505 ENOG4105HZG regulatoR CS348_07525 ENOG4108KMM Diguanylate cyclase CS348_07530 ENOG4105D9N nucleoside CS348_07565 ENOG4105EFV Major head subunit CS348_07585 ENOG4109076 Conserved Protein CS348_07590 ENOG4105CPC Aldo Keto reductase CS348_07595 ENOG4107RA9 decarboxylase CS348_07610 ENOG4105CHM Aminotransferase CS348_07615 ENOG4105D1S lipid A biosynthesis CS348_07620 ENOG4105W9M Membrane CS348_07630 ENOG4105CXY transporter CS348_07640 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC CS348_07650 ENOG4107TXD phosphoglycerate transport system transcriptional regulatory protein pgta CS348_07655 ENOG4108NC2 Outer membrane protease CS348_07665 ENOG4105S64 Formate nitrite transporter CS348_07670 ENOG410903C (LipO)protein CS348_07675 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation CS348_07685 ENOG4105KZW UPF0381 protein CS348_07700 ENOG4108BY2 phosphohistidine phosphatase CS348_07710 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) CS348_07725 ENOG4105EJ9 Membrane CS348_07730 ENOG4108BPE -transporting atpase CS348_07735 ENOG4105MH2 YfcL protein CS348_07740 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) CS348_07745 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CS348_07765 ENOG4105R8V Transcriptional regulator CS348_07780 ENOG4106WZ1 flagella biosynthesis regulator CS348_07790 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) CS348_07800 ENOG4105DQR SNARE associated Golgi CS348_07810 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase CS348_07815 ENOG4108S3P Sporulation domain protein CS348_07820 ENOG4105E96 Colicin v production protein CS348_07825 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase CS348_07840 ENOG4105E5D amino acid CS348_07845 ENOG4106M28 alanine racemase domain protein CS348_07855 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase CS348_07865 ENOG4105E89 ABC transporter CS348_07870 ENOG4105E89 ABC transporter CS348_07875 ENOG4105DSP amino acid AbC transporter CS348_07880 ENOG4106YG3 ABC transporter CS348_07885 ENOG4108JEH abc transporter atp-binding protein CS348_07890 ENOG4105ECP epimerase CS348_07895 ENOG4105CYM Glutathione S-transferase CS348_07900 ENOG4108SHQ Glutathione S-transferase CS348_07905 ENOG4108RE9 Phosphodiesterase CS348_07910 ENOG4105PTV Nudix Hydrolase CS348_07915 ENOG4105K2J Transcriptional regulator CS348_07925 ENOG4106ETB IIa component CS348_07935 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC CS348_07940 ENOG4108HHA Transketolase CS348_07945 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) CS348_07950 ENOG4105CSX c4-dicarboxylate anaerobic carrier CS348_07955 ENOG4105C6K Malic enzyme CS348_07960 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) CS348_07975 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 CS348_07980 ENOG4107QWE )-transporter CS348_07990 ENOG4105CHM Aminotransferase CS348_08000 ENOG4107NQ8 LysR family Transcriptional regulator CS348_08025 ENOG4105GKE subunit e CS348_08030 ENOG4107QIZ NADH dehydrogenase CS348_08035 ENOG4107R0R NADH dehydrogenase subunit g CS348_08050 ENOG4107UFS subunit j CS348_08060 ENOG4105D65 subunit l CS348_08065 ENOG4105C8S subunit m CS348_08075 ENOG4107R88 Chemotaxis protein (CheV) CS348_08085 ENOG4107YB6 acetyltransferase, (GNAT) family CS348_08090 ENOG4105TNS Conserved Protein CS348_08095 ENOG4105E4F Isochorismate synthase CS348_08110 ENOG4108IPT Naphthoate synthase CS348_08120 ENOG4105CEY Amp-dependent synthetase and ligase CS348_08125 ENOG4106GZG polymyxin resistance protein B CS348_08160 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase CS348_08175 ENOG4108UII YfaZ family CS348_08185 ENOG4107258 Transcriptional regulator CS348_08195 ENOG4105CSP Major Facilitator Superfamily CS348_08215 ENOG4105Z6G Protease that can act as an efficient and specific deubiquitinating enzyme in vitro. Does not possess desumoylating and deneddylating activities. The physiological substrate is CS348_08225 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) CS348_08235 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A CS348_08240 ENOG4105CXY transporter CS348_08245 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase CS348_08250 ENOG4105GZI Transcriptional regulator CS348_08255 ENOG4105CZM Major Facilitator CS348_08260 ENOG4105XPH Ferredoxin CS348_08265 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CS348_08270 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CS348_08290 ENOG4105CXK mandelate racemase muconate lactonizing CS348_08300 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CS348_08305 ENOG4105BZU Histidine kinase CS348_08310 ENOG41068CG regulatoR CS348_08315 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC CS348_08325 ENOG4105FCK Membrane CS348_08330 ENOG4105CJ2 (LipO)protein CS348_08335 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) CS348_08340 ENOG4105CF1 Alkylated DNA repair protein CS348_08345 ENOG4105IBP Cyclic peptide transporter CS348_08355 ENOG4108ZNS ferredoxin-type protein NapF CS348_08360 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase CS348_08370 ENOG4108BGM Quinol dehydrogenase periplasmic component CS348_08375 ENOG4105GXZ Ferredoxin-type protein NapH CS348_08385 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) CS348_08390 ENOG4105CUW cytochrome C-TYPE protein CS348_08400 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) CS348_08405 ENOG41060IM Heme exporter protein CS348_08410 ENOG4105X3C heme exporter protein CS348_08415 ENOG4108ZKK Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity) CS348_08420 ENOG4105DA4 cytochrome c-type biogenesis protein CS348_08425 ENOG4107QX9 Thiol disulfide interChange protein CS348_08430 ENOG4105KWW Biogenesis protein CS348_08435 ENOG4105WH1 Two component transcriptional regulator luxr family CS348_08470 ENOG4105E68 Sulfatase CS348_08490 ENOG4105CFI type iii restriction protein res subunit CS348_08495 ENOG4105I08 Pseudouridine synthase CS348_08500 ENOG4105C2C drug resistance transporter, Bcr CflA CS348_08510 ENOG4105HG6 CS348_08515 ENOG4108JQ5 ABC transporter CS348_08520 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component CS348_08525 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component CS348_08530 ENOG4105E43 Extracellular solute-binding protein, family 5 CS348_08535 ENOG4105CXC rtn protein CS348_08545 ENOG4107TT5 NLP P60 protein CS348_08555 ENOG41076MN Phosphoesterase, PA-phosphatase related CS348_08560 ENOG4105CKI cobalamin synthesis protein CS348_08565 ENOG4105FUQ Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) CS348_08575 ENOG4105KRS Proteinase inhibitor CS348_08590 ENOG4105S8Q sugar efflux transporter CS348_08595 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein CS348_08600 ENOG4105DE4 1-phosphofructokinase CS348_08605 ENOG4105DM4 PTS System CS348_08615 ENOG4105HMI Membrane CS348_08620 ENOG4105DUM transcriptional regulator, lysR family CS348_08625 ENOG4108IQI permease CS348_08635 ENOG4105D05 Receptor CS348_08640 ENOG4105CXY transporter CS348_08645 ENOG4105EAC phosphoserine phosphatase CS348_08650 ENOG4105EJQ L-serine dehydratase CS348_08675 ENOG4105DHF Membrane CS348_08680 ENOG41060NJ transcriptional regulator CS348_08685 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator CS348_08690 ENOG4105C2J ABC transporter CS348_08695 ENOG4107SDZ Galactoside transport system permease protein mglC CS348_08700 ENOG4107SJI Dehydrogenase CS348_08705 ENOG4105BZ8 glutamate synthase CS348_08715 ENOG4105Y9N Membrane CS348_08720 ENOG4107GZ4 SanA protein CS348_08730 ENOG41067MG lrgb family CS348_08760 ENOG4108RXX maleylacetoacetate isomerase CS348_08765 ENOG4105MSY salicylate hydroxylase CS348_08770 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) CS348_08780 ENOG4105ETP RND efflux system, outer membrane lipoprotein CS348_08785 ENOG4105H9W Short-chain dehydrogenase reductase Sdr CS348_08790 ENOG4105KHU inner membrane protein YohD CS348_08795 ENOG41069YE inner membrane protein yohC CS348_08805 ENOG41061WM D-Alanyl-D-Alanine CS348_08810 ENOG4105CXG d-lactate dehydrogenase CS348_08815 ENOG4107QK4 glycoside hydrolase, family 3 domain protein CS348_08820 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system CS348_08825 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component CS348_08830 ENOG4108IJ8 ABC transporter CS348_08835 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component CS348_08850 ENOG4108HRK Histidine kinase CS348_08855 ENOG4108NEV two component transcriptional regulator, LytTR family CS348_08860 ENOG4108W15 Protein of unknown function (DUF1456) CS348_08870 ENOG4108YCW (LipO)protein CS348_08880 ENOG4105D1F ATP-binding protein CS348_08895 ENOG4108MQF Chaperone CS348_08900 ENOG4105CW0 outer membrane usher protein CS348_08910 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly CS348_08920 ENOG4105DWF phosphomethylpyrimidine kinase CS348_08925 ENOG4105FDP GntR family transcriptional regulator CS348_08930 ENOG4108TFM Kinase, PfkB family CS348_08935 ENOG4108KD5 ADP-ribosylation crystallin J1 CS348_08940 ENOG4105EAA nucleoside CS348_08945 ENOG4105EIE fructose-bisphosphate aldolase CS348_08960 ENOG41090V3 Tir chaperone protein (CesT) family CS348_08970 ENOG4105CFP Peptidase U32 CS348_08995 ENOG4105E3W Two component transcriptional regulator (Winged helix family CS348_09000 ENOG4105EB3 Histidine kinase CS348_09020 ENOG4105ENT Efflux transporter rnd family, mfp subunit CS348_09025 ENOG4105R8A Heat shock protein CS348_09035 ENOG4105D03 DNA-3-methyladenine glycosylase II CS348_09040 ENOG4105BZU Histidine kinase CS348_09055 ENOG4108GAE asmA family CS348_09060 ENOG4105EE5 Membrane protein terC CS348_09070 ENOG4105DAY polysaccharide export protein CS348_09075 ENOG4105KJF protein tyrosine phosphatase CS348_09080 ENOG4105D75 Capsular exopolysaccharide family CS348_09085 ENOG41090RK glycosyl transferase CS348_09090 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB CS348_09095 ENOG4107RXY Glycosyl transferase CS348_09100 ENOG4108NYJ Colanic acid CS348_09105 ENOG4105ECJ Glycosyl Transferase CS348_09110 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF CS348_09115 ENOG4105C0K Gdp-mannose 4,6-dehydratase CS348_09120 ENOG4105C30 Nad-dependent epimerase dehydratase CS348_09125 ENOG4105FGF GDP-mannose mannosyl hydrolase CS348_09130 ENOG4106CD9 glycosyl transferase group 1 CS348_09135 ENOG4105CJT Mannose-1-phosphate guanylyltransferase CS348_09140 ENOG4107QKV phosphomannomutase CS348_09145 ENOG4105D3Q Sugar transferase CS348_09150 ENOG4105PSV Polysaccharide Biosynthesis Protein CS348_09155 ENOG4105C74 pyruvyl transferase CS348_09160 ENOG4107T8Q Glycosyl transferase (Group 1 CS348_09165 ENOG4105G1A colanic acid biosynthesis protein CS348_09170 ENOG4105DMT epimerase dehydratase CS348_09175 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase CS348_09180 ENOG4105ER6 polysaccharide biosynthesis protein CS348_09185 ENOG4105ECJ Glycosyl Transferase CS348_09200 ENOG4105CMR udp-glucose 4-epimerase CS348_09210 ENOG4105C0K Gdp-mannose 4,6-dehydratase CS348_09215 ENOG4105C30 Nad-dependent epimerase dehydratase CS348_09220 ENOG4105FGF GDP-mannose mannosyl hydrolase CS348_09240 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) CS348_09250 ENOG4105C6Y Udp-glucose 6-dehydrogenase CS348_09255 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) CS348_09260 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase CS348_09305 ENOG4108535 NAD dependent epimerase/dehydratase family CS348_09310 ENOG4105EQ1 Transcriptional regulator CS348_09315 ENOG4105CUB amino acid CS348_09320 ENOG4105CJB Exodeoxyribonuclease I CS348_09340 ENOG4108J2R molybdopterin oxidoreductase CS348_09345 ENOG4105QAX Iron-sulfur CS348_09350 ENOG4108NWD Cytochrome CS348_09355 ENOG4105DZ1 carboxypeptidase CS348_09360 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) CS348_09365 ENOG4105DR8 Membrane CS348_09375 ENOG4105JZC GHMP kinase CS348_09380 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) CS348_09385 ENOG4105KTW ethanolamine utilization protein CS348_09390 ENOG4105M3W utilization protein CS348_09400 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) CS348_09410 ENOG4108EKI Dehydrogenase CS348_09420 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml CS348_09430 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) CS348_09435 ENOG4105S3V Carbon dioxide concentrating mechanism protein CS348_09440 ENOG4105KNY Microcompartments protein CS348_09450 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit CS348_09455 ENOG4108ZFT Dehydratase small subunit CS348_09460 ENOG4105YCI dehydratase medium subunit CS348_09465 ENOG4105DMB glycerol dehydratase CS348_09470 ENOG4105EHR propanediol utilization protein pduB CS348_09475 ENOG4105KNY Microcompartments protein CS348_09480 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) CS348_09485 ENOG4107XVH Transcriptional regulator CS348_09490 ENOG4105C0Y Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) CS348_09500 ENOG41081F0 Precorrin-8x methylmutase CS348_09510 ENOG4108DR9 Cobalt-precorrin-6Y C(5)-methyltransferase CS348_09515 ENOG4107XSI cobalt-precorrin-6y C15-methyltransferase CS348_09520 ENOG4105CIA precorrin-4 C(11)-methyltransferase CS348_09525 ENOG4108P62 biosynthesis protein (CbiG) CS348_09530 ENOG4105E4R Precorrin-3B C17-methyltransferase CS348_09535 ENOG4105QUC reductase CS348_09540 ENOG4107PPM cobalt chelatase CS348_09545 ENOG4105DVK Precorrin-2 c20-methyltransferase CS348_09550 ENOG4105CFT Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) CS348_09560 ENOG4108V4M Cobalt abc transporter CS348_09565 ENOG4108JJB ABC transporter CS348_09575 ENOG4108YZT Adenosylcobinamide kinase CS348_09590 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein CS348_09605 ENOG4105CXN decarboxylase CS348_09620 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase CS348_09635 ENOG41085FC arsR family transcriptional regulator CS348_09640 ENOG4108UXE Protein tyrosine phosphatase CS348_09655 ENOG4105D6J arsenicaL-resistance protein CS348_09675 ENOG4105UQX Mate efflux family protein CS348_09705 ENOG4105FYV Amp nucleosidase CS348_09750 ENOG4105KT5 UmuD protein CS348_09755 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) CS348_09770 ENOG4105FCK Membrane CS348_09775 ENOG4105Y0K Inner membrane protein YedR CS348_09780 ENOG4105EST Metal Dependent Phosphohydrolase CS348_09785 ENOG4105DVF Cytosine-specific methyltransferase CS348_09790 ENOG41090BB DNA mismatch endonuclease (vsr) CS348_09795 ENOG4105FDR Membrane CS348_09800 ENOG4105CKW Inner membrane protein yedI CS348_09805 ENOG4105VNZ cytoplasmic protein CS348_09820 ENOG4105YX3 cellular response to acidity CS348_09830 ENOG4107TKS colanic acid capsular biosynthesis activation protein A CS348_09835 ENOG4105D19 Role in flagellar biosynthesis (By similarity) CS348_09840 ENOG4105VS8 Flagellar biosynthetic protein fliq CS348_09845 ENOG4105CN7 Flagellar biosynthetic protein FliP CS348_09850 ENOG4105K0P flagellar biosynthesis protein CS348_09855 ENOG4105DD5 Flagellar motor switch protein CS348_09860 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) CS348_09865 ENOG4107ZI8 flagellar basal body-associated protein flil CS348_09870 ENOG4105WF4 Flagellar hook-length control protein CS348_09875 ENOG4105GSA Flagellar export protein flij CS348_09880 ENOG4108JIR Flagellum-specific ATP synthase CS348_09885 ENOG41090PJ Flagellar assembly protein CS348_09890 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) CS348_09895 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) CS348_09910 ENOG4105KSU Redox protein CS348_09915 ENOG41066VF YeeE YedE family protein CS348_09920 ENOG4105JCU Inherit from NOG: (Lipo)protein CS348_09925 ENOG4105E5K Alpha-amylase CS348_09935 ENOG4105MQ3 flagellar protein FliS CS348_09940 ENOG4105DTS flagellar hook-associated CS348_09955 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CS348_09960 ENOG4108M9K flagella biosynthesis protein FliZ CS348_09965 ENOG4105EAB amino acid AbC transporter CS348_09975 ENOG4105E5Q amino acid AbC transporter CS348_09980 ENOG4105CDA abc transporter atp-binding protein CS348_09985 ENOG4105VJY transcriptional regulator CS348_09990 ENOG4105XVG cytoplasmic protein CS348_10000 ENOG4105WH1 Two component transcriptional regulator luxr family CS348_10045 ENOG4106RHG Yeca family CS348_10050 ENOG4105E0U tyrosine-specific transport protein CS348_10055 ENOG4105VVZ metal-binding protein CS348_10060 ENOG41090A1 ferritin CS348_10065 ENOG4105P23 (LipO)protein CS348_10075 ENOG4108UEC Ferritin-like protein CS348_10090 ENOG4108K4C ec 3.1.3.12 CS348_10100 ENOG4108VA4 Universal stress protein CS348_10110 ENOG4105GEH Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity) CS348_10115 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region CS348_10120 ENOG4107RD7 Flagellar Motor Protein, MotA CS348_10125 ENOG4105ER2 Ompa motb domain protein CS348_10130 ENOG4105CBS Chea signal transduction histidine kinase CS348_10135 ENOG4108V3W Chemotaxis protein, CheW CS348_10140 ENOG4105C8Q Methyl-accepting chemotaxis CS348_10145 ENOG4105BZU Histidine kinase CS348_10155 ENOG4108VYJ response regulator receiver protein CS348_10160 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) CS348_10165 ENOG4105D00 flagellar biosynthetic protein flhB CS348_10170 ENOG4105D7B Flagellar biosynthesis protein flha CS348_10175 ENOG4105IRD Flagellar protein FlhE CS348_10180 ENOG4105F5H Glycosyl Hydrolase Family 88 CS348_10195 ENOG4106ZCM YecM protein CS348_10220 ENOG4105WJG Glutathione CS348_10225 ENOG41081XQ Conserved Protein CS348_10230 ENOG4105D3W isochorismatase CS348_10240 ENOG4108TIT dATP pyrophosphohydrolase CS348_10255 ENOG4107S01 Repressor protein MetJ CS348_10275 ENOG4105FAV ABC, transporter CS348_10285 ENOG4105NXV High-affinity zinc uptake system protein CS348_10290 ENOG4105DR5 peptidase CS348_10300 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase CS348_10305 ENOG4105CA9 Pyruvate kinase CS348_10310 ENOG4106KNT transcriptional regulator CS348_10320 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase CS348_10325 ENOG4105C01 Dihydroxy-acid dehydratase CS348_10330 ENOG4108UHU Aldolase CS348_10340 ENOG4105X2V dna damage-inducible protein CS348_10350 ENOG4108Q2J Inner membrane protein YebE CS348_10355 ENOG4105CUG Oligopeptidase b CS348_10360 ENOG4105UMD exodeoxyribonuclease X CS348_10365 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase CS348_10370 ENOG4105MPK DNA polymerase III subunit theta CS348_10375 ENOG4105FXM Copper resistance protein CS348_10380 ENOG4108PNC copper resistance CS348_10385 ENOG4105NKT exported protein CS348_10410 ENOG4108YV9 Protein of unknown function (DUF2514) CS348_10435 ENOG410685N tail fiber protein CS348_10445 ENOG4105UZW Tail fiber assembly protein CS348_10485 ENOG4105DWP Membrane CS348_10515 ENOG4105UZW Tail fiber assembly protein CS348_10530 ENOG41064WM Uncharacterized protein YcgX CS348_10545 ENOG4108R1E Serine threonine protein phosphatase 1 CS348_10550 ENOG4105UVW uncharacterized protein yebW CS348_10555 ENOG4105WT8 Protein of unknown function (DUF1480) CS348_10565 ENOG4105DY2 Paraquat-inducible protein b CS348_10570 ENOG4105H2K paraquat-inducible protein a CS348_10575 ENOG4108ZGC gaf domain protein CS348_10585 ENOG4105CN1 protease CS348_10595 ENOG4105C0R drug resistance transporter emrb qaca subfamily CS348_10600 ENOG4105J4Q Transcriptional regulator CS348_10615 ENOG4105Q3Y exported protein CS348_10620 ENOG410610J Protein of unknown function (DUF2627) CS348_10625 ENOG4105VEQ Cold shock protein CS348_10630 ENOG4105CJN penicillin-binding protein CS348_10635 ENOG4105DHI Methyltransferase CS348_10655 ENOG4105F3R pts system mannose fructose sorbose family iid CS348_10660 ENOG4105ETZ PTS System CS348_10665 ENOG4108EQA pts system CS348_10675 ENOG4105EE5 Membrane protein terC CS348_10680 ENOG4107XTP (EAL) domain protein CS348_10685 ENOG4105EJQ L-serine dehydratase CS348_10695 ENOG4105CRQ synthase (Component I) CS348_10705 ENOG4105M4H endoribonuclease L-psp CS348_10710 ENOG4105DVT helicase CS348_10715 ENOG41072GX Peptidase M22 Glycoprotease CS348_10720 ENOG4105Y4Z Outer Membrane Lipoprotein CS348_10730 ENOG4105CEY Amp-dependent synthetase and ligase CS348_10735 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) CS348_10745 ENOG4107QMS site-determining protein CS348_10760 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase CS348_10775 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation CS348_10800 ENOG4105ED1 spovr family CS348_10810 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) CS348_10820 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A CS348_10830 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) CS348_10845 ENOG4105D82 Glutamate dehydrogenase CS348_10855 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii CS348_10860 ENOG4105C4M (Ubiquinol oxidase) subunit I CS348_10865 ENOG4105MVP hydrogenase-1 operon protein HyaF CS348_10870 ENOG4108VXY Hydrogenase-1 operon protein HyaE CS348_10875 ENOG4108USZ hydrogenase CS348_10880 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit CS348_10890 ENOG4105E3S small subunit CS348_10905 ENOG4105C3G gtp-binding protein CS348_10915 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria CS348_10920 ENOG4105CHH sulfate transporter CS348_10925 ENOG4105C5T Phosphoribosyl pyrophosphate synthase CS348_10950 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) CS348_10955 ENOG4108YY7 Invasion gene expression up-regulator SirB CS348_10960 ENOG41063JG Transcriptional regulator CS348_10970 ENOG4105EWV Sodium calcium exchanger membrane region CS348_10975 ENOG4105WS7 Cation transport regulator CS348_10980 ENOG41090EX DsrE family CS348_10985 ENOG4105ID0 Putative invasin CS348_10990 ENOG4105WH1 Two component transcriptional regulator luxr family CS348_10995 ENOG4105BZU Histidine kinase CS348_11005 ENOG4105DQQ Major facilitator superfamily MFS_1 CS348_11010 ENOG4105CRU nitrate reductase, alpha subunit CS348_11015 ENOG4108IUE nitrate reductase beta subunit CS348_11020 ENOG4105R3A Nitrate reductase CS348_11025 ENOG41076YT nitrate reductase, gamma subunit CS348_11065 ENOG4105CIY formyltetrahydrofolate deformylase CS348_11075 ENOG4105D78 K07001 NTE family protein CS348_11080 ENOG4105I93 response regulator CS348_11085 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase CS348_11100 ENOG4108EKI Dehydrogenase CS348_11105 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein CS348_11115 ENOG4107QSI ABC, transporter CS348_11120 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CS348_11125 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CS348_11130 ENOG4105C3U ABC transporter CS348_11135 ENOG4108JQ7 (ABC) transporter CS348_11140 ENOG4105EYW Ion transport protein CS348_11160 ENOG4105K9H YciI-like protein CS348_11165 ENOG410822N TonB family CS348_11170 ENOG4105NAU thioesterase Superfamily protein CS348_11185 ENOG4105PI0 Ferredoxin CS348_11195 ENOG4105EIF outer membrane protein W CS348_11200 ENOG4105WEF catalase CS348_11205 ENOG4108N8X transition metal ion binding CS348_11210 ENOG4108Z9Z response to DNA damage stimulus CS348_11230 ENOG4105DK0 Indole-3-glycerol phosphate synthase CS348_11235 ENOG4108EFP Anthranilate synthase component II CS348_11240 ENOG4105CRQ synthase (Component I) CS348_11250 ENOG4105DB7 PHP domain protein CS348_11255 ENOG4107RTD sua5 ycio yrdc ywlc family protein CS348_11260 ENOG4105FE9 pseudouridine synthase CS348_11265 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase CS348_11270 ENOG4105UBK short-chain dehydrogenase reductase CS348_11275 ENOG4105ERU peptidase CS348_11280 ENOG4105RKX Protein of unknown function (DUF2498) CS348_11290 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) CS348_11300 ENOG4107R11 Transcriptional regulator CS348_11320 ENOG4107QM5 aconitate hydratase CS348_11330 ENOG4105EYK Phosphatidylglycerophosphatase B CS348_11340 ENOG4105Q4A inner membrane protein yciS CS348_11345 ENOG4105CFV Tetratricopeptide repeat protein CS348_11355 ENOG4108ZJT translation initiation factor, Sui1 CS348_11360 ENOG41061RM osmotically inducible lipoprotein CS348_11365 ENOG4105N2W Transcriptional regulator CS348_11375 ENOG4105BZU Histidine kinase CS348_11390 ENOG4105Q4T oxidoreductase CS348_11395 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH CS348_11420 ENOG4108JQ2 peptide transport system atp-binding protein CS348_11425 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein CS348_11430 ENOG4108EU3 peptide transport system, permease CS348_11470 ENOG4108C33 Resolvase CS348_11475 ENOG4108I5W peptide transport system, permease protein CS348_11480 ENOG4108J59 Extracellular solute-binding protein, family 5 CS348_11485 ENOG4105E51 psp operon transcriptional activator CS348_11490 ENOG41087YS Phage shock protein A CS348_11495 ENOG4105YYT phage shock protein B CS348_11500 ENOG4105FM1 phage shock protein C CS348_11505 ENOG4105NNG Peripheral inner membrane phage-shock protein CS348_11510 ENOG4105K8Z Phage shock protein CS348_11515 ENOG4105CM6 amino acid regulated cytosolic protein CS348_11525 ENOG4108JU8 Transcriptional regulator CS348_11530 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) CS348_11535 ENOG4107S8C mandelate racemase muconate lactonizing CS348_11540 ENOG4105KXI murein peptide amidase A CS348_11545 ENOG4107QSI ABC, transporter CS348_11555 ENOG4105HEI LysR family (Transcriptional regulator CS348_11560 ENOG4105CV8 reductase CS348_11565 ENOG4105F6U Short-chain dehydrogenase reductase Sdr CS348_11570 ENOG4108XFH Transcriptional regulator CS348_11585 ENOG4106PHM regulatory protein CS348_11610 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) CS348_11630 ENOG4105D64 Mechanosensitive ion channel CS348_11635 ENOG4105S5I Membrane CS348_11640 ENOG4105Q9Y Universal stress protein CS348_11650 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) CS348_11655 ENOG4108DG9 Smr protein MutS2 CS348_11665 ENOG4105C8Q Methyl-accepting chemotaxis CS348_11680 ENOG4105C1J atp-dependent rna helicase CS348_11700 ENOG410814C multidrug resistance protein CS348_11705 ENOG4108RW8 Universal stress protein F CS348_11715 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) CS348_11730 ENOG41090X5 Heat shock protein hslJ CS348_11735 ENOG4105C5I Dehydrogenase CS348_11740 ENOG4107H52 Dicarboxylate transport CS348_11745 ENOG410689M (LipO)protein CS348_11750 ENOG4105WXT Conserved Protein CS348_11765 ENOG4105CQ7 ATP-dependent helicase CS348_11770 ENOG4107DB1 DUF218 domain CS348_11775 ENOG4105CPW cytochrome b561 CS348_11780 ENOG4108WF3 methyltransferase CS348_11790 ENOG4105E5Q amino acid AbC transporter CS348_11800 ENOG4105E5Q amino acid AbC transporter CS348_11805 ENOG4107R0W ABC transporter CS348_11815 ENOG4107ZUJ lipid metabolic process CS348_11845 ENOG4105C8Q Methyl-accepting chemotaxis CS348_11850 ENOG4105DDW LysR family Transcriptional regulator CS348_11855 ENOG4105E32 cytoplasmic protein CS348_11860 ENOG4105EBR Carboxylesterase CS348_11870 ENOG4108YYC ycei family CS348_11885 ENOG4108PQ7 sgc region transcriptional regulator CS348_11890 ENOG4108RK0 3-epimerase CS348_11895 ENOG4108XBJ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) CS348_11900 ENOG4106P19 photosystem i assembly btpa CS348_11905 ENOG4105DT3 PTS system, galactitol-specific IIc component CS348_11910 ENOG4105K18 The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) CS348_11915 ENOG4105CN9 Peptidase m42 family protein CS348_11920 ENOG4108Z9I -acetyltransferase CS348_11925 ENOG4107WE3 acetyltransferase YdcK CS348_11930 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein CS348_11935 ENOG41088CC tellurite resistance protein tehB CS348_11940 ENOG4108KKZ (LipO)protein CS348_11945 ENOG4105DKK Benzoate CS348_11950 ENOG4108JCI Transcriptional regulator CS348_11955 ENOG4105CFP Peptidase U32 CS348_11960 ENOG4105RR0 Protein of unknown function (DUF2554) CS348_11980 ENOG4108UQS dipeptidase CS348_11985 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family CS348_11990 ENOG4105C26 Dehydrogenase CS348_12000 ENOG410654E Membrane CS348_12020 ENOG4105R71 cytoplasmic protein CS348_12025 ENOG4108T9Y Inner membrane protein ydcZ CS348_12030 ENOG4108Z7F N-acetyltransferase CS348_12035 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein CS348_12040 ENOG4108WYP Transcriptional regulator CS348_12045 ENOG4105CHB tonB-dependent Receptor CS348_12050 ENOG4108NS2 receptor CS348_12055 ENOG4105SUV lipoprotein YgdR CS348_12060 ENOG4105C85 amino acid CS348_12080 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase CS348_12085 ENOG4105JAB phenazine biosynthesis protein, phzf family CS348_12090 ENOG4105D0D Nitrate reductase 2, gamma subunit CS348_12095 ENOG4108NZN Respiratory nitrate reductase 2 delta chain CS348_12100 ENOG4108IUE nitrate reductase beta subunit CS348_12105 ENOG4105CRU nitrate reductase, alpha subunit CS348_12110 ENOG4107QND Nitrite extrusion protein CS348_12145 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CS348_12150 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CS348_12155 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein CS348_12160 ENOG4108MG3 formate dehydrogenase CS348_12165 ENOG4105DQ4 alcohol dehydrogenase CS348_12180 ENOG4105TPS biofilm-dependent modulation protein CS348_12185 ENOG4108Z9K Osmotically inducible protein CS348_12205 ENOG4105XXV Acid-resistance protein CS348_12215 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) CS348_12230 ENOG4105C87 Aminotransferase class I and II CS348_12235 ENOG4105DFD Na H antiporter CS348_12240 ENOG41060NJ transcriptional regulator CS348_12250 ENOG4105CBN LysR family transcriptional regulator CS348_12290 ENOG4108UQ8 endoribonuclease L-psp CS348_12295 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) CS348_12305 ENOG4107SCK Monooxygenase CS348_12320 ENOG4108I5G Major Facilitator superfamily CS348_12325 ENOG4105CPQ Dehydrogenase CS348_12330 ENOG4105C6F GntR Family Transcriptional Regulator CS348_12345 ENOG4105DPX Hydrogenase, large subunit CS348_12350 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit CS348_12370 ENOG4105MVP hydrogenase-1 operon protein HyaF CS348_12395 ENOG4105FFC UPF0187 protein CS348_12400 ENOG4105M0C cytoplasmic protein CS348_12410 ENOG4105C26 Dehydrogenase CS348_12415 ENOG4105EGI Transcriptional regulator CS348_12430 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes CS348_12440 ENOG4106DNR multiple antibiotic resistance protein CS348_12445 ENOG4108594 Permease of the drug metabolite transporter CS348_12450 ENOG4105E5W Transporter CS348_12460 ENOG4108YDI single-species biofilm formation on inanimate substrate CS348_12465 ENOG4108WTK competence damage-inducible protein CS348_12480 ENOG4105DGW oligopeptidase A CS348_12485 ENOG4105EMU Dehydrogenase CS348_12490 ENOG4107XBN GntR Family Transcriptional Regulator CS348_12495 ENOG41061EV selenium-binding protein YdfZ CS348_12500 ENOG4105DEI Mannitol dehydrogenase CS348_12510 ENOG4105CPQ Dehydrogenase CS348_12530 ENOG4108MK9 spermidine N(1)-acetyltransferase CS348_12540 ENOG4105KBG Protein of unknown function (DUF1161) CS348_12550 ENOG4105C3J Cysteine desulfurase CS348_12555 ENOG4105QAX Iron-sulfur CS348_12560 ENOG4107KGK dmso reductase anchor subunit CS348_12565 ENOG4108NEM leader-binding protein dmsD CS348_12570 ENOG4108U0I binding-protein-dependent transport systems inner membrane Component CS348_12575 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system CS348_12580 ENOG4105E90 ABC transporter CS348_12585 ENOG4108IJ8 ABC transporter CS348_12590 ENOG4105CMQ Chloride channel CS348_12595 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) CS348_12600 ENOG4105DAG ROK family CS348_12610 ENOG4106NZI LysR family Transcriptional regulator CS348_12615 ENOG4105D94 Major Facilitator Superfamily CS348_12630 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap CS348_12650 ENOG4105DSF transport protein CS348_12655 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) CS348_12660 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) CS348_12665 ENOG4105C5D exported protein CS348_12670 ENOG4105D5Q Arginine ornithine antiporter CS348_12675 ENOG4105RA2 Membrane CS348_12680 ENOG4107EXC regulatoR CS348_12690 ENOG4105FCK Membrane CS348_12695 ENOG4105CPN adenine deaminase CS348_12700 ENOG4105JJR Histidine kinase CS348_12710 ENOG4105C9Q fumarate hydratase class II CS348_12715 ENOG4107GFK fumarate CS348_12720 ENOG4105EIP mannose-6-phosphate isomerase CS348_12725 ENOG4106J39 exported protein CS348_12730 ENOG4107P2S Transcriptional regulator CS348_12735 ENOG4105CI1 PTS System CS348_12740 ENOG4105C87 Aminotransferase class I and II CS348_12750 ENOG4105D9R oxidoreductase CS348_12755 ENOG4106C6R beta-lactam resistance protein CS348_12765 ENOG4105M9B inner membrane protein ydgK CS348_12790 ENOG4108UQQ Electron transport complex CS348_12800 ENOG4105CSM endonuclease III CS348_12805 ENOG4105DUX Transporter CS348_12810 ENOG4108K3A Glutathione S-transferase CS348_12830 ENOG410642K Lysozyme inhibitor CS348_12840 ENOG4108XTF Outer Membrane Lipoprotein CS348_12855 ENOG4105Y49 secretion protein, HlyD family CS348_12860 ENOG4105DSW Fusaric acid resistance protein CS348_12865 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CS348_12870 ENOG4107RGM aldo keto reductase CS348_12875 ENOG4105XZD Fe-S protein CS348_12880 ENOG4108WUH Transcriptional regulator, TetR family CS348_12885 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase CS348_12890 ENOG4108UYE Lactoylglutathione lyase CS348_12900 ENOG4105M2J Glutaredoxin CS348_12905 ENOG4105K4H Nlp p60 protein CS348_12910 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CS348_12930 ENOG4105F52 Transcriptional regulator CS348_12935 ENOG4105CZQ inner membrane transport protein YdhC CS348_12940 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase CS348_12945 ENOG4108R6K riboflavin synthase, subunit alpha CS348_12965 ENOG4108IUF type iii secretion CS348_12970 ENOG4108TN6 type iii secretion CS348_12975 ENOG41083GP type iii secretion CS348_12980 ENOG4108HHI Type III secretion system protein CS348_12985 ENOG41063Q7 Type III secretion system protein CS348_13000 ENOG4108JIR Flagellum-specific ATP synthase CS348_13010 ENOG4106H1D secretion system apparatus protein CS348_13015 ENOG4105UQF type iii secretion CS348_13020 ENOG4106563 type III secretion system apparatus protein CS348_13070 ENOG4106FZW pathogenicity island effector protein CS348_13075 ENOG4108SZ7 secretion system effector CS348_13085 ENOG4105ZQI secreted protein CS348_13120 ENOG4105BZU Histidine kinase CS348_13130 ENOG4108XDN Transcriptional regulator CS348_13135 ENOG4107SEY Conserved Protein CS348_13140 ENOG4105RFR Protein of unknown function (DUF2767) CS348_13145 ENOG4108ZXC Two component transcriptional regulator, luxr family CS348_13150 ENOG4106AFQ Histidine kinase CS348_13155 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein CS348_13160 ENOG4106WHD Tetrathionate reductase CS348_13165 ENOG4105DB1 molybdopterin oxidoreductase CS348_13170 ENOG4108RVA ribokinase CS348_13180 ENOG4107RCM Releases the N-terminal proline from various substrates (By similarity) CS348_13185 ENOG4105CUB amino acid CS348_13190 ENOG4105CA9 Pyruvate kinase CS348_13205 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein CS348_13220 ENOG4105JRK feS assembly protein SufD CS348_13225 ENOG4105C3K feS assembly ATPase SufC CS348_13230 ENOG4105DIW FeS assembly protein SUFB CS348_13235 ENOG4108Z4V iron-sulfur cluster assembly CS348_13240 ENOG4108ETY sodium dicarboxylate symporter CS348_13245 ENOG410671Z uncharacterized protein ydiH CS348_13250 ENOG4105KA0 thioesterase Superfamily protein CS348_13255 ENOG4105CQB FAD linked oxidase domain protein CS348_13260 ENOG4105IPI Membrane CS348_13270 ENOG4105SUA Ydil protein CS348_13275 ENOG4105EMV Major Facilitator CS348_13280 ENOG4105EMV Major Facilitator CS348_13295 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) CS348_13300 ENOG4105C1G acyl-Coa dehydrogenase CS348_13305 ENOG4105W4W Transcriptional regulator CS348_13310 ENOG4105CV7 Electron transfer flavoprotein CS348_13315 ENOG4105C10 Electron transfer flavoprotein CS348_13320 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase CS348_13325 ENOG41090P5 ferredoxin-like protein CS348_13330 ENOG4105CEY Amp-dependent synthetase and ligase CS348_13335 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) CS348_13345 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) CS348_13350 ENOG4106EDX Hemin uptake protein CS348_13365 ENOG4108QBX (LipO)protein CS348_13375 ENOG4108V06 Glutathione peroxidase CS348_13390 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CS348_13455 ENOG4105VZ1 Replication Protein CS348_13485 ENOG4105ED4 portal protein CS348_13530 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 CS348_13565 ENOG4108X9F tail fiber protein CS348_13620 ENOG41060TC Hok gef cell toxic protein CS348_13625 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) CS348_13630 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) CS348_13640 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) CS348_13645 ENOG41082NX 50s ribosomal protein l35 CS348_13650 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) CS348_13680 ENOG4108NE3 Salt-induced outer membrane protein CS348_13685 ENOG4105DE4 1-phosphofructokinase CS348_13690 ENOG4105P10 Uncharacterized protein ydiZ CS348_13695 ENOG4105FGM Fructosamine kinase CS348_13700 ENOG4107PN8 YfeABCD locus regulator CS348_13705 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 CS348_13710 ENOG4107K5X Membrane-bound metal-dependent hydrolase CS348_13715 ENOG4108ETY sodium dicarboxylate symporter CS348_13725 ENOG4105CH6 catalase CS348_13735 ENOG4105F8D glycoside hydrolase family 4 CS348_13740 ENOG4105EZV Transcriptional regulator CS348_13745 ENOG4105VCP PTS System CS348_13750 ENOG4105CK1 PTS System CS348_13755 ENOG4105VZJ PTS System CS348_13765 ENOG4105KKI DNA-binding transcriptional activator OsmE CS348_13775 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) CS348_13780 ENOG4108SPG Periplasmic Protein CS348_13820 ENOG4105CGK Exodeoxyribonuclease III CS348_13825 ENOG4105M6F mutator MutT protein CS348_13830 ENOG4105MTM Protein of unknown function (DUF1496) CS348_13835 ENOG4105D82 Glutamate dehydrogenase CS348_13840 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) CS348_13845 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) CS348_13855 ENOG41069NU Nitroreductase CS348_13865 ENOG4105D07 Signal peptide peptidase, SppA CS348_13870 ENOG4105HDK L-asparaginase CS348_13875 ENOG4108RWI nicotinamidase CS348_13880 ENOG4105VUT cytoplasmic protein CS348_13890 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase CS348_13900 ENOG4105DSB aldose 1-epimerase CS348_13905 ENOG4105CV8 reductase CS348_13910 ENOG4105C4X radical SAM domain protein CS348_13915 ENOG4105GNX MltA-interacting MipA family protein CS348_13920 ENOG4105CYN Serine protein kinase CS348_13930 ENOG4108KHP Diguanylate cyclase CS348_13935 ENOG4108KXH Ybak prolyl-tRNA synthetase associated CS348_13950 ENOG4105R1U AraC Family Transcriptional Regulator CS348_13955 ENOG4105DJ2 Major Facilitator Superfamily CS348_13960 ENOG4105K78 MarR family Transcriptional regulator CS348_13970 ENOG4105UCG Domain of unknown function (DUF333) CS348_13975 ENOG4106G4W CS348_13980 ENOG4105Y3U Transglycosylase-associated protein CS348_13995 ENOG4105YP6 Domain of unknown function (DUF1869) CS348_14000 ENOG4108YS1 cytoplasmic protein CS348_14015 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) CS348_14035 ENOG4108Z6Z Transcriptional regulator CS348_14050 ENOG4108MEK Metal-binding protein YodA CS348_14065 ENOG4105D64 Mechanosensitive ion channel CS348_14070 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) CS348_14075 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) CS348_14100 ENOG4108VKM cytochrome b561 CS348_14115 ENOG4108ZNX Heat shock protein CS348_14140 ENOG4105H38 Membrane CS348_14160 ENOG41060EU Cold shock-like protein CS348_14165 ENOG4106F2Y RICIN CS348_14170 ENOG4105Y50 Virulence Protein CS348_14180 ENOG4108TMH cytolethal distending toxin CS348_14215 ENOG4108HMX isocitrate dehydrogenase (NADP) CS348_14220 ENOG4108R99 pseudouridine synthase CS348_14245 ENOG4107QTF adenylosuccinate lyase CS348_14260 ENOG4105EZE Cupin 4 family protein CS348_14285 ENOG4105F38 ABC transporter, permease CS348_14295 ENOG4105D38 putrescine abc transporter CS348_14300 ENOG4107RUE extracellular solute-binding protein family 1 CS348_14305 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) CS348_14315 ENOG4105D60 lipoprotein releasing system transmembrane protein CS348_14325 ENOG4105D60 lipoprotein releasing system transmembrane protein CS348_14330 ENOG4108JA2 transcriptioN-repair coupling factor CS348_14340 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction CS348_14345 ENOG4108IND Tetr family transcriptional regulator CS348_14350 ENOG4107MBR 17 kDa surface antigen CS348_14355 ENOG4105CEP NADH dehydrogenase CS348_14375 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) CS348_14380 ENOG41090DQ Lipoprotein CS348_14385 ENOG4105K59 histidine triad (HIT) protein CS348_14390 ENOG4105CNM Receptor CS348_14395 ENOG4105CI1 PTS System CS348_14400 ENOG4105F8V Hydrolase, tatD family CS348_14405 ENOG4107QRG dna polymerase iii CS348_14415 ENOG4105HHA aminodeoxychorismate lyase CS348_14420 ENOG4105YAZ 4-amino-4-deoxychorismate lyase CS348_14425 ENOG4106UCC Fimbrial protein CS348_14430 ENOG4108NAE Fimbrial chaperone protein CS348_14435 ENOG4105CW0 outer membrane usher protein CS348_14455 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CS348_14460 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) CS348_14465 ENOG4105CHR reductase CS348_14470 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase CS348_14490 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein CS348_14495 ENOG4108UHJ MAF-like protein CS348_14510 ENOG4105EI2 Pseudouridine synthase CS348_14515 ENOG41071G1 Uncharacterized protein YceQ CS348_14520 ENOG4107QQB Ribonuclease E CS348_14525 ENOG4105DTJ flagellar hook-associated protein CS348_14530 ENOG4105E1Q flagellar hook-associated protein CS348_14535 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj CS348_14550 ENOG4105CGA flagellar basal-body rod protein FlgG CS348_14555 ENOG4108KPB Flagellar basal-body rod protein FlgF CS348_14560 ENOG4105BZE flagellar hook protein, FlgE CS348_14565 ENOG4105W00 Flagellar hook capping protein CS348_14570 ENOG4108ZC9 flagellar basal-body rod protein flgc CS348_14575 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) CS348_14585 ENOG4105CKS Flagella basal body P-ring formation protein flgA CS348_14590 ENOG4105M9M anti-sigma28 factor FlgM CS348_14595 ENOG4105QVD Flagella synthesis protein FlgN CS348_14600 ENOG4105CJR Integral membrane protein (MviN CS348_14605 ENOG4105EP9 oxidoreductase CS348_14615 ENOG4105D9U N-acetyltransferase CS348_14625 ENOG4105E9S glutaredoxin 2 CS348_14630 ENOG4105F3T (LipO)protein CS348_14640 ENOG4105MEA DNA damage-inducible protein i CS348_14645 ENOG4105PVA Biofilm formation regulatory protein BssS CS348_14655 ENOG4106974 biofilm formation CS348_14665 ENOG4105DS1 cytochrome b561 CS348_14670 ENOG4108YYC ycei family CS348_14680 ENOG4105D1S lipid A biosynthesis CS348_14695 ENOG4108W47 Acidic protein msyB CS348_14700 ENOG4105NAC (LipO)protein CS348_14705 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) CS348_14720 ENOG4107RZC phospholipase d CS348_14725 ENOG4108UVJ appr-1-p processing domain protein CS348_14750 ENOG41086KC Transcriptional regulator CS348_14755 ENOG4108XDW curli assembly protein CsgE CS348_14760 ENOG4108WYR Curli production assembly transport component, CsgF CS348_14765 ENOG4105P8Q Curli production assembly transport component CsgG CS348_14770 ENOG4108UQ5 membrane protein YcdZ CS348_14775 ENOG4107XHZ cytoplasmic chaperone TorD family protein CS348_14805 ENOG4107RJ5 oxidoreductase CS348_14810 ENOG4105JHE Major Facilitator Superfamily CS348_14815 ENOG4108QGT oligogalacturonate-specific porin CS348_14825 ENOG4105C9S Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity) CS348_14835 ENOG4107RJ1 sodium solute CS348_14840 ENOG4105QEK Transcriptional regulator CS348_14845 ENOG4105D5M phosphate starvation-inducible protein CS348_14855 ENOG4105CK7 Sodium proline symporter CS348_14875 ENOG4108R86 Transcriptional regulator CS348_14880 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 CS348_14890 ENOG4105XH3 CS348_14895 ENOG4105D6F Phosphatase CS348_14900 ENOG4105N2G alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen CS348_14905 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) CS348_14910 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) CS348_14975 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase CS348_14980 ENOG4105C26 Dehydrogenase CS348_14990 ENOG4108V8F Transcriptional regulator, MarR family CS348_14995 ENOG4105EFA 4-hydroxyphenylacetate CS348_15000 ENOG4107UWN reductase CS348_15010 ENOG4105VT2 5-hydroxyisourate hydrolase CS348_15015 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CS348_15020 ENOG4107ZY3 Histidine kinase CS348_15035 ENOG4106YSC CS348_15040 ENOG4108N4M Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns 3-P and prevents the transition of PtdIns 3-P to PtdIns 3,5-P2. It is one of the known effectors injected by Salmonella into the host cell and is required for invasion and for an efficient generation and maintenance of Salmonella-containing vacuole (SVC). Alteration of the phosphoinositide composition of the plasma membrane causes membrane ruffling and actin cytoskeleton rearrangements. The persistence of PtdIns 3-P diverts the SCV from the endocytic pathway resulting in enlarged vesicles, which are essential to create a favorable environment where Salmonella can replicate and avoid immune defenses of the host cell CS348_15055 ENOG41084BJ Pentapeptide repeat protein CS348_15070 ENOG4108MN8 Membrane CS348_15080 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 CS348_15090 ENOG4108V1U phospholipid-binding protein CS348_15105 ENOG4105K4P CoA-binding domain protein CS348_15120 ENOG41088T4 Helicase IV CS348_15125 ENOG410901E Membrane CS348_15130 ENOG4105EM2 membrane CS348_15135 ENOG4108RZ1 DNA transformation protein CS348_15145 ENOG4105UYK outer membrane protein a CS348_15155 ENOG4105DAN ATP-dependent protease CS348_15165 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) CS348_15170 ENOG4108Q2G (LipO)protein CS348_15175 ENOG4105DY2 Paraquat-inducible protein b CS348_15180 ENOG4105F1S paraquat-inducible protein a CS348_15185 ENOG4105C5H ABC transporter CS348_15195 ENOG4105QVC MOSC domain-containing protein CS348_15200 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) CS348_15210 ENOG4105CD8 aminopeptidase N CS348_15225 ENOG4105FCK Membrane CS348_15230 ENOG4105CGF Aromatic amino acid aminotransferase CS348_15235 ENOG4105C5X domain protein CS348_15240 ENOG4105EAQ (twin-arginine translocation) pathway signal CS348_15250 ENOG4105DIT ErfK YbiS YcfS YnhG family protein CS348_15260 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) CS348_15270 ENOG4106371 Methyltransferase CS348_15275 ENOG4107S90 membrAne CS348_15280 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups CS348_15290 ENOG4105W49 UPF0434 protein CS348_15295 ENOG4105T0Z Conserved Protein CS348_15310 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 CS348_15315 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) CS348_15320 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) CS348_15330 ENOG4108K0D peptidase, M48 CS348_15335 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase CS348_15345 ENOG4107VMU Membrane CS348_15350 ENOG4105DDY UPF0142 protein ycaO CS348_15355 ENOG4105TMB Formate nitrite transporter CS348_15360 ENOG4105C6N Formate acetyltransferase CS348_15365 ENOG4105GUS CS348_15370 ENOG4105F1A Pyruvate formate-lyase CS348_15375 ENOG4105E5D amino acid CS348_15385 ENOG4107KGK dmso reductase anchor subunit CS348_15390 ENOG4105QAX Iron-sulfur CS348_15395 ENOG4107QY8 reductase CS348_15405 ENOG4105D1H recombination factor protein RarA CS348_15415 ENOG4105CNU cell division protein FtsK CS348_15420 ENOG4105EW9 transcriptional regulator AsnC family CS348_15430 ENOG4105C3M thioredoxin reductase CS348_15435 ENOG4108JJ9 ABC, transporter CS348_15440 ENOG4108JJ8 (ABC) transporter CS348_15455 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) CS348_15460 ENOG4105HEI LysR family (Transcriptional regulator CS348_15465 ENOG4105EUB pirin domain protein CS348_15470 ENOG4105CHJ isochorismatase hydrolase CS348_15480 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CS348_15490 ENOG4105VEQ Cold shock protein CS348_15495 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) CS348_15500 ENOG4105DJY efflux transporter, rnd family, mfp subunit CS348_15505 ENOG4108MJ5 VirK protein CS348_15510 ENOG4105CPB ATP-dependent endonuclease of the OLD family CS348_15520 ENOG4105DWU Membrane CS348_15530 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) CS348_15535 ENOG4105C7K acetolactate synthase CS348_15540 ENOG4105C5W Aldolase CS348_15545 ENOG4105CGD Nad-dependent epimerase dehydratase CS348_15550 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase CS348_15555 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase CS348_15565 ENOG4105Y50 Virulence Protein CS348_15585 ENOG41090WB Transposase is3 is911 CS348_15595 ENOG4105Y9F tail fiber protein CS348_15600 ENOG4105Y0G tail protein CS348_15605 ENOG4108T86 baseplate J family protein CS348_15645 ENOG4105TKZ Tail Sheath CS348_15690 ENOG4105CAR Terminase, large subunit CS348_15715 ENOG4108YV9 Protein of unknown function (DUF2514) CS348_15720 ENOG4105NVB glycoside hydrolase, family 19 CS348_15735 ENOG4105HGD Antitermination protein CS348_15815 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) CS348_15850 ENOG4107R08 Integrase CS348_15855 ENOG41064MM (LipO)protein CS348_15860 ENOG4105E5Z arginine transporter ATP-binding subunit CS348_15865 ENOG4106PMH Extracellular solute-binding protein family 3 CS348_15870 ENOG4105GBT ABC transporter CS348_15875 ENOG4105DMR ABC, transporter CS348_15880 ENOG4106TNF Periplasmic binding protein CS348_15910 ENOG4105RBQ inner membrane protein ybjO CS348_15915 ENOG4105D38 putrescine abc transporter CS348_15920 ENOG4105F38 ABC transporter, permease CS348_15925 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CS348_15930 ENOG4107RUE extracellular solute-binding protein family 1 CS348_15935 ENOG4108RMJ sensory transduction regulator CS348_15945 ENOG4108DBC nitroreductase CS348_15950 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress CS348_15955 ENOG41090BQ Glutaredoxin CS348_15960 ENOG4105GWF inner membrane protein YbjM CS348_15975 ENOG4108RFG Tetr family transcriptional regulator CS348_15980 ENOG4106UW1 Major Facilitator superfamily CS348_15985 ENOG4108HCJ Hydrolase CS348_15990 ENOG4107QF7 multi-drug CS348_15995 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase CS348_16000 ENOG4107FB0 transcriptional regulator DeoR family CS348_16005 ENOG4105DZ1 carboxypeptidase CS348_16010 ENOG4108TGY Glutathione S-transferase CS348_16015 ENOG4105D8V Glucose sorbosone dehydrogenase CS348_16020 ENOG4105D8V Glucose sorbosone dehydrogenase CS348_16025 ENOG4105CY2 Citrate transporter CS348_16030 ENOG4108KB2 LysR family Transcriptional regulator CS348_16035 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase CS348_16040 ENOG4105C1G acyl-Coa dehydrogenase CS348_16045 ENOG4108M9J MaoC like domain protein CS348_16055 ENOG4105BZJ Electron transfer flavoprotein CS348_16060 ENOG4105CI0 Citrate lyase CS348_16070 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway CS348_16090 ENOG4105DEF Extracellular solute-binding protein, family 5 CS348_16095 ENOG4108JQ6 ABC transporter CS348_16100 ENOG4105D44 asparaginase CS348_16105 ENOG4105CVM Molybdenum cofactor synthesis domain protein CS348_16110 ENOG4105D06 uba thif-type nad fad binding protein CS348_16115 ENOG4105F1A Pyruvate formate-lyase CS348_16120 ENOG4105C6N Formate acetyltransferase CS348_16125 ENOG4108HCJ Hydrolase CS348_16130 ENOG41072TH Protein of unknown function (DUF1479) CS348_16135 ENOG4105C5H ABC transporter CS348_16140 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein CS348_16145 ENOG4105F4P )-transporter CS348_16150 ENOG4105KST dependent repressor CS348_16160 ENOG4108I6E Sulfatase CS348_16165 ENOG4108T1M outer membrane protein x CS348_16180 ENOG4107R0W ABC transporter CS348_16185 ENOG4105E5Q amino acid AbC transporter CS348_16190 ENOG4105CDA abc transporter atp-binding protein CS348_16195 ENOG4105D8X mechanosensitive ion channel CS348_16205 ENOG4105KSC Transcriptional regulator, TraR DksA family CS348_16210 ENOG4105VR4 UPF0379 protein ybiJ CS348_16215 ENOG4108MTB glycosyl transferase family CS348_16220 ENOG4105DVT helicase CS348_16225 ENOG4105C1J atp-dependent rna helicase CS348_16230 ENOG4107MVR Transcriptional regulator CS348_16240 ENOG4105CJ1 ABC, transporter CS348_16245 ENOG4107QWP ABC-2 type transporter CS348_16250 ENOG4107QWP ABC-2 type transporter CS348_16255 ENOG4105I9U inner membrane protein ybhQ CS348_16260 ENOG4105X23 Endonuclease Exonuclease phosphatase CS348_16265 ENOG4105DZQ phospholipase D Transphosphatidylase CS348_16270 ENOG4107UXM Membrane CS348_16295 ENOG4105HFZ Membrane CS348_16300 ENOG4108ZAF Molybdopterin CS348_16305 ENOG4105M00 molybdopterin converting factor, subunit 1 CS348_16315 ENOG4108RIR Molybdenum cofactor biosynthesis protein CS348_16325 ENOG4105CHW UPF0052 protein CS348_16350 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) CS348_16355 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) CS348_16370 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) CS348_16375 ENOG4108V1U phospholipid-binding protein CS348_16405 ENOG4105NBR Pectinesterase CS348_16415 ENOG4108K4B hydrolase CS348_16425 ENOG4105E0C molybdate abc transporter CS348_16430 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein CS348_16435 ENOG410680R Protein of unknown function (DUF2592) CS348_16440 ENOG4105F4R Transcriptional regulator mode CS348_16450 ENOG4105DKW ABC transporter CS348_16460 ENOG4105CMR udp-glucose 4-epimerase CS348_16465 ENOG4105F0Z galactose-1-phosphate uridylyltransferase CS348_16475 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) CS348_16490 ENOG4105E0A ABC, transporter CS348_16495 ENOG4105EHG Permease protein CS348_16500 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) CS348_16505 ENOG4105JND homeobox protein CS348_16510 ENOG4105PGM cation diffusion facilitator family transporter CS348_16515 ENOG4106Z1T Nicotinamide Mononucleotide Transporter CS348_16565 ENOG4105UFD tol-pal system protein YbgF CS348_16570 ENOG4105KCK Peptidoglycan-associated lipoprotein CS348_16580 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA CS348_16585 ENOG4105M8F Biopolymer transport protein exbD tolR CS348_16590 ENOG4105E02 MotA TolQ exbB proton channel CS348_16595 ENOG4107YD3 Thioesterase CS348_16600 ENOG4105KJB cyd operon protein YbgE CS348_16610 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii CS348_16615 ENOG4105C4M (Ubiquinol oxidase) subunit I CS348_16620 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha CS348_16630 ENOG4105C7S Dehydrogenase CS348_16635 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 CS348_16640 ENOG4105E33 succinate dehydrogenase CS348_16645 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) CS348_16650 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein CS348_16655 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit CS348_16670 ENOG4105BZN citrate synthase CS348_16675 ENOG4108KK1 membrane protein AbrB duplication CS348_16690 ENOG4107R7A Allophanate hydrolase subunit 2 CS348_16695 ENOG4105P4J Allophanate hydrolase, subunit 1 CS348_16700 ENOG4107QNR UPF0135 protein CS348_16715 ENOG4105CVP deoxyribo-dipyrimidine photolyase CS348_16720 ENOG4105XIQ Protein of unknown function (DUF2517) CS348_16740 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) CS348_16745 ENOG4105C08 Histidine kinase CS348_16750 ENOG4105EEX Two component transcriptional regulator (Winged helix family CS348_16755 ENOG4105CXN decarboxylase CS348_16760 ENOG4105D5Q Arginine ornithine antiporter CS348_16770 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 CS348_16775 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) CS348_16780 ENOG4105EV9 Alpha Beta Hydrolase CS348_16785 ENOG4105NNH LexA regulated protein CS348_16790 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) CS348_16795 ENOG41090R7 Ferric uptake CS348_16800 ENOG4106P55 Transcriptional regulator CS348_16805 ENOG4107EFR Flavocytochrome c CS348_16810 ENOG41079YP Citrate utilization protein b CS348_16815 ENOG4105CSH Transporter CS348_16820 ENOG4105GX6 (LipO)protein CS348_16825 ENOG4105J5J Outer membrane porin CS348_16835 ENOG4105CI1 PTS System CS348_16845 ENOG4105CE4 GlcNAc 6-P deacetylase CS348_16850 ENOG4105E2R ROK family CS348_16855 ENOG4105D4U had-superfamily hydrolase, subfamily iia CS348_16860 ENOG4105CAQ asparagine synthetase CS348_16900 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family CS348_16910 ENOG4105C9A Phoh family CS348_16920 ENOG4108JU5 Magnesium and cobalt efflux protein CS348_16925 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) CS348_16935 ENOG4107RP9 extracellular solute-binding protein, family 3 CS348_16940 ENOG4105EAD ABC transporter CS348_16945 ENOG4105DRP amino acid AbC transporter CS348_16950 ENOG4105CDA abc transporter atp-binding protein CS348_16960 ENOG4107PAI alpha helical protein CS348_16965 ENOG4108JUB Transcriptional regulator CS348_16970 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) CS348_16995 ENOG4105DJF DNA polymerase III, delta' subunit CS348_17000 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) CS348_17005 ENOG4107QZB decarboxylase CS348_17010 ENOG4108TGR phosphatase CS348_17015 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) CS348_17025 ENOG4105CJN penicillin-binding protein CS348_17030 ENOG4105CNI cell division protein FtsW CS348_17035 ENOG4105K6T rare lipoprotein A CS348_17040 ENOG4105DZ1 carboxypeptidase CS348_17045 ENOG4108Z43 UPF0250 protein CS348_17055 ENOG41064T2 transcriptional regulator, lysR family CS348_17070 ENOG4107QPI nitrilase cyanide hydratase and apolipoprotein n-acyltransferase CS348_17080 ENOG4105VEQ Cold shock protein CS348_17095 ENOG4105CEE C4-dicarboxylate transporter CS348_17100 ENOG4106YYS transcriptional regulatory protein CS348_17105 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism CS348_17115 ENOG4105DUA (citrate (pro-3S)-lyase ligase CS348_17120 ENOG4105XGS Covalent carrier of the coenzyme of citrate lyase (By similarity) CS348_17125 ENOG4105CI0 Citrate lyase CS348_17130 ENOG4105CHY citrate lyase, alpha CS348_17135 ENOG4105YGP holo-ACP synthase CitX CS348_17145 ENOG4107QPK )-transporter CS348_17150 ENOG4105KTS ribonuclease CS348_17160 ENOG4105NXH GreA GreB family elongation factor CS348_17165 ENOG4105E2A Dehydrogenase CS348_17170 ENOG4108U51 Universal stress protein CS348_17180 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein CS348_17185 ENOG4107QY8 reductase CS348_17195 ENOG4108JU3 Alkyl hydroperoxide reductase CS348_17200 ENOG4105D3R alkyl hydroperoxide reductase CS348_17205 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase CS348_17215 ENOG4105DQS Transcriptional regulator CS348_17220 ENOG4105BZV Phosphoadenosine phosphosulfate reductase CS348_17225 ENOG4105GTN ParB Domain Protein Nuclease CS348_17230 ENOG4105CHM Aminotransferase CS348_17235 ENOG4107SCQ Iron-containing alcohol dehydrogenase CS348_17240 ENOG4105VCD cytoplasmic protein CS348_17245 ENOG4105D22 carbon starvation protein CS348_17255 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase CS348_17260 ENOG4105WQI isochorismatase CS348_17265 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase CS348_17270 ENOG4105E4F Isochorismate synthase CS348_17275 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein CS348_17280 ENOG4105E8G Major facilitator Superfamily CS348_17285 ENOG4105DQ5 transport system permease protein CS348_17290 ENOG4105TVJ transport system, permease CS348_17295 ENOG4105E0A ABC, transporter CS348_17300 ENOG4108QY5 Ferric enterobactin transport protein CS348_17305 ENOG4105C0W non-ribosomal peptide synthetase CS348_17310 ENOG41085A6 mbth domain-containing protein CS348_17315 ENOG4105E93 esterase CS348_17320 ENOG4107RNH Outer membrane receptor FepA CS348_17325 ENOG4108TSE Transferase CS348_17335 ENOG4105WQ6 Membrane CS348_17340 ENOG4105HFT AraC family transcriptional regulator CS348_17345 ENOG41067SE Tetr family transcriptional regulator CS348_17350 ENOG4105MSB protein, conserved in bacteria CS348_17355 ENOG4108RCM Nitroreductase CS348_17370 ENOG4105C85 amino acid CS348_17380 ENOG4108KBJ Inner membrane protein YkgB CS348_17385 ENOG41066GK UPF0379 protein ykgI CS348_17390 ENOG4107QN2 dihydrolipoyl dehydrogenase CS348_17395 ENOG4108K01 transcriptional regulator CS348_17400 ENOG4108IJF Heavy metal efflux pump, CzcA CS348_17405 ENOG4105GR3 Histidine kinase CS348_17445 ENOG41090WB Transposase is3 is911 CS348_17450 ENOG4105UZW Tail fiber assembly protein CS348_17455 ENOG4108X9F tail fiber protein CS348_17455 ENOG4108X9F tail fiber protein CS348_17525 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) CS348_17585 ENOG4105HGD Antitermination protein CS348_17665 ENOG4105DFP Integrase CS348_17680 ENOG4106KCD HTH_LUXR CS348_17690 ENOG4106721 fimbriae Y protein CS348_17695 ENOG4108Q9V regulatoR CS348_17700 ENOG4108ZI2 Fimbrial protein CS348_17705 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) CS348_17710 ENOG4105CW0 outer membrane usher protein CS348_17715 ENOG4108AF8 Chaperone CS348_17725 ENOG4108WDE Fimbrial protein CS348_17740 ENOG4105WQ3 Rna-binding protein CS348_17765 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) CS348_17780 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) CS348_17785 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit CS348_17795 ENOG4108UMI ABC transporter, permease CS348_17800 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) CS348_17805 ENOG4105D01 (LipO)protein CS348_17815 ENOG4105CV6 ABC transporter, permease CS348_17820 ENOG4108I0Y (ABC) transporter CS348_17825 ENOG4108UJV acyl-CoA thioesterase i CS348_17830 ENOG4105E1F short-chain dehydrogenase reductase CS348_17835 ENOG4107QR8 Thioredoxin CS348_17840 ENOG4105C4B ABC transporter, permease CS348_17845 ENOG41083J0 (ABC) transporter CS348_17850 ENOG4107QX8 SPFH domain, Band 7 family protein CS348_17855 ENOG4105G5H Membrane CS348_17860 ENOG4108Z6Z Transcriptional regulator CS348_17865 ENOG4105C59 p-type ATPase CS348_17875 ENOG4105MBR gumn family CS348_17880 ENOG4108Z66 YbaK ebsC protein CS348_17885 ENOG4105CGH 5'-nucleotidase CS348_17890 ENOG4105EU0 Major facilitator Superfamily CS348_17895 ENOG4105CKD glutathione-regulated potassium-efflux system protein CS348_17900 ENOG4107RE1 Inosine-guanosine kinase CS348_17905 ENOG4105F2M alpha beta hydrolase fold-3 domain protein CS348_17940 ENOG4107QMP dna polymerase iii subunits gamma and tau CS348_17955 ENOG4105WD1 Membrane CS348_17960 ENOG4108URS primosomal replication protein n'' CS348_17965 ENOG4106428 Protein of unknown function (DUF2496) CS348_17975 ENOG4105EGS Mechanosensitive ion channel CS348_17980 ENOG4108IG5 Transcriptional regulator CS348_17985 ENOG4105C1P efflux transporter, rnd family, mfp subunit CS348_17990 ENOG4105BZS acriflavin resistance protein CS348_17995 ENOG4108UKR Biofilm formation regulator YbaJ CS348_18005 ENOG4108UW5 maltose o-acetyltransferase CS348_18010 ENOG4105GSJ Inner membrane protein ylaC CS348_18025 ENOG41066DG (EAL) domain protein CS348_18035 ENOG41080UX Methyltransferase CS348_18040 ENOG4108MNP Glycoprotein polysaccharide metabolism CS348_18045 ENOG4105C29 acyl-CoA thioesterase CS348_18050 ENOG4105BZU Histidine kinase CS348_18055 ENOG4108YZA Nitrogen regulatory protein pii CS348_18060 ENOG4105BZ1 (ABC) transporter CS348_18065 ENOG4105BZ1 (ABC) transporter CS348_18070 ENOG4108XM1 transcriptional regulator AsnC family CS348_18085 ENOG4108NFA extracellular solute-binding protein CS348_18095 ENOG4108TGP Thioesterase superfamily protein CS348_18100 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein CS348_18105 ENOG4105EIN peptidylprolyl cis-trans isomerase CS348_18110 ENOG4105K70 DNA-binding protein CS348_18115 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) CS348_18140 ENOG4105M85 Bola protein CS348_18150 ENOG4105IEY (LipO)protein CS348_18155 ENOG4105EYM Major Facilitator superfamily CS348_18160 ENOG4105E2S oxidase) subunit II CS348_18165 ENOG4105BZ9 Cytochrome C oxidase, subunit I CS348_18170 ENOG4105CCU oxidase (Subunit III) CS348_18175 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) CS348_18185 ENOG4107RDB Major Facilitator CS348_18195 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) CS348_18200 ENOG4107S0N DJ-1 family CS348_18225 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CS348_18230 ENOG4108MP3 ABC transporter, permease CS348_18235 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component CS348_18250 ENOG4105CTB Polyprenyl synthetase CS348_18260 ENOG4105CPC Aldo Keto reductase CS348_18265 ENOG4108ZAI phosphatidylglycerophosphatase a CS348_18270 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) CS348_18275 ENOG4107YIM Involved in the transcription termination process (By similarity) CS348_18285 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) CS348_18295 ENOG4108KIC (LipO)protein CS348_18300 ENOG4105DRB nucleoside-specific channel-forming protein CS348_18315 ENOG4105N1F Hnh endonuclease CS348_18320 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) CS348_18330 ENOG4105VIE preprotein translocase, subunit YajC CS348_18355 ENOG4105D3R alkyl hydroperoxide reductase CS348_18360 ENOG4107R28 alpha amylase, catalytic region CS348_18365 ENOG4105C85 amino acid CS348_18370 ENOG4105CWM branched-chain amino acid transport system II carrier protein CS348_18375 ENOG4105BZU Histidine kinase CS348_18380 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CS348_18385 ENOG4107RH8 nuclease SbcCD subunit D CS348_18390 ENOG4105EYH Exonuclease CS348_18395 ENOG4105F27 Major Facilitator CS348_18400 ENOG4105DKQ ROK family CS348_18415 ENOG4105HBA AroM protein CS348_18420 ENOG4105SS3 CS348_18435 ENOG4105II7 pyrroline-5-carboxylate reductase CS348_18440 ENOG4105BZU Histidine kinase CS348_18445 ENOG4105VIF phosphate starvation-inducible protein CS348_18470 ENOG4105CPF Cell wall formation (By similarity) CS348_18475 ENOG4105UNH Membrane CS348_18480 ENOG4105FR5 inner membrane protein YaiY CS348_18485 ENOG4107QS8 (LipO)protein CS348_18490 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 CS348_18500 ENOG4107R6D beta-lactam binding protein AmpH CS348_18505 ENOG4108PNB DNA-binding transcriptional regulator CS348_18510 ENOG4108NSE outer membrane autotransporter barrel CS348_18515 ENOG4105D52 delta-aminolevulinic acid dehydratase CS348_18520 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) CS348_18525 ENOG4105DXD 2-methylcitrate dehydratase CS348_18530 ENOG4105BZN citrate synthase CS348_18535 ENOG4105CR4 methylisocitrate lyase CS348_18540 ENOG4108JU7 Transcriptional regulator CS348_18545 ENOG4105TDT uncharacterized protein yahO CS348_18550 ENOG4105E82 cytochrome subunit of dehydrogenase CS348_18570 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii CS348_18575 ENOG4105C4M (Ubiquinol oxidase) subunit I CS348_18585 ENOG4105D8D Type III CS348_18590 ENOG4107QMH DNA methylase CS348_18595 ENOG4105JHE Major Facilitator Superfamily CS348_18625 ENOG4105ENJ RND efflux system, outer membrane lipoprotein CS348_18645 ENOG4108T1M outer membrane protein x CS348_18660 ENOG4107XTP (EAL) domain protein CS348_18690 ENOG4105X0I Fimbrial CS348_18695 ENOG4108VEV chaperone CS348_18700 ENOG4105CW0 outer membrane usher protein CS348_18735 ENOG4105FCK Membrane CS348_18755 ENOG4105CIN aminoacyl-histidine dipeptidase CS348_18760 ENOG4108S2Y peptide Chain Release factor CS348_18775 ENOG4105F7V ErfK ybiS ycfS ynhG family protein CS348_18780 ENOG4105E7A Glutamine amidotransferase CS348_18790 ENOG4107QPN acyl-Coa dehydrogenase CS348_18795 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase CS348_18810 ENOG4105T40 surface antigen msp4 family protein CS348_18830 ENOG4108XM1 transcriptional regulator AsnC family CS348_18845 ENOG4105NI8 Cytosine-specific methyltransferase CS348_18870 ENOG4105UZW Tail fiber assembly protein CS348_18890 ENOG4108T86 baseplate J family protein CS348_18900 ENOG4105PZ7 Baseplate assembly protein CS348_18910 ENOG4108NKR DNA circulation protein CS348_18935 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CS348_18975 ENOG4108JDX DNA polymerase iii, epsilon subunit CS348_18985 ENOG4105D1A Methyltransferase CS348_18995 ENOG4105E9H Lytic Murein transglycosylase CS348_19000 ENOG4105F2W methyltransferase CS348_19010 ENOG4105F27 Major Facilitator CS348_19015 ENOG4105HEI LysR family (Transcriptional regulator CS348_19020 ENOG4105CV8 reductase CS348_19055 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase CS348_19060 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) CS348_19065 ENOG4108UMI ABC transporter, permease CS348_19070 ENOG4105D01 (LipO)protein CS348_19075 ENOG4108R8X outer membrane lipoprotein CS348_19080 ENOG4108R96 Methyltransferase, YaeB family CS348_19090 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion CS348_19095 ENOG4108YZN class I peptide chain release factor CS348_19100 ENOG4108VWS Yaeq family CS348_19110 ENOG4105M1T rho-binding antiterminator CS348_19120 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase CS348_19125 ENOG4105CXN decarboxylase CS348_19140 ENOG4105C0B DNA polymerase III (alpha subunit) CS348_19185 ENOG4105KNE Phosphatidate cytidylyltransferase CS348_19235 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) CS348_19255 ENOG4105CSH Transporter CS348_19270 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR CS348_19275 ENOG4105C0H protease CS348_19290 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) CS348_19295 ENOG4105EN6 Membrane CS348_19315 ENOG4105S6R Iron-hydroxamate transporter permease subunit CS348_19320 ENOG4105J76 Periplasmic binding protein CS348_19325 ENOG4105E0A ABC, transporter CS348_19330 ENOG4105E0K tonB-dependent siderophore receptor CS348_19335 ENOG4105BZ4 penicillin-binding protein CS348_19340 ENOG4105CQ7 ATP-dependent helicase CS348_19345 ENOG4107XID 2'-5' rna ligase CS348_19355 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters CS348_19365 ENOG4105DJ0 Poly(A) Polymerase CS348_19370 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase CS348_19380 ENOG4108VEV chaperone CS348_19385 ENOG4105CW0 outer membrane usher protein CS348_19390 ENOG4108XEY fimbrial-like adhesin protein CS348_19395 ENOG4105SYG Fimbrial protein CS348_19400 ENOG4105SN2 fimbrial-like adhesin protein CS348_19405 ENOG4105P0Q fimbrial-like protein YadC CS348_19410 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) CS348_19430 ENOG4107BJW polysaccharide deacetylase CS348_19435 ENOG4108YTN IIa component CS348_19445 ENOG4108UIF Chaperone CS348_19450 ENOG4105CW0 outer membrane usher protein CS348_19455 ENOG4105E3A (ABC) transporter CS348_19460 ENOG4105DA5 (ABC) transporter CS348_19465 ENOG41077A9 carbonic anhydrase CS348_19470 ENOG4108UGV hypoxanthine phosphoribosyltransferase CS348_19475 ENOG4105DZG Dehydrogenase CS348_19480 ENOG4105E3B Multicopper oxidase CS348_19485 ENOG4108ZRK uncharacterized protein yacC CS348_19500 ENOG4105MVE transcriptional regulator CS348_19505 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) CS348_19510 ENOG4107S2N Type III effector Hrp-dependent CS348_19525 ENOG4107QIJ Aconitate hydratase 2 CS348_19530 ENOG4108NST exported protein CS348_19545 ENOG4107QN2 dihydrolipoyl dehydrogenase CS348_19550 ENOG4107QSN dihydrolipoamide acetyltransferase CS348_19555 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) CS348_19565 ENOG41073TP transcriptional regulator CS348_19570 ENOG4105C85 amino acid CS348_19575 ENOG4105CT4 transporter CS348_19580 ENOG4105CUK Alpha-N-arabinofuranosidase (EC 3.2.1.55) CS348_19585 ENOG4106A72 regulatory protein AmpE CS348_19595 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase CS348_19605 ENOG4108ZUW Major pilin subunit CS348_19610 ENOG4107QHF type ii secretion system protein e CS348_19615 ENOG4105D7Q type ii secretion system CS348_19625 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) CS348_19650 ENOG4105M6F mutator MutT protein CS348_19670 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) CS348_19675 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) CS348_19680 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) CS348_19685 ENOG4105CPF Cell wall formation (By similarity) CS348_19700 ENOG4105CNI cell division protein FtsW CS348_19715 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) CS348_19720 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) CS348_19725 ENOG4105CJN penicillin-binding protein CS348_19730 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) CS348_19745 ENOG4107B7Y DNA-binding transcriptional regulator FruR CS348_19750 ENOG4108ZP8 Acetolactate synthase small subunit CS348_19755 ENOG4105C7K acetolactate synthase CS348_19760 ENOG41064T2 transcriptional regulator, lysR family CS348_19785 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) CS348_19800 ENOG4105DP9 ABC transporter CS348_19805 ENOG4106SMU thiamine transporter membrane protein CS348_19810 ENOG4107T0D ABC, transporter CS348_19815 ENOG4108KF1 Membrane CS348_19820 ENOG41063TF transcriptional regulator (AraC CS348_19835 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase CS348_19855 ENOG4105CQ2 DNA polymerase CS348_19865 ENOG4105D3G Pseudouridine synthase CS348_19875 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) CS348_19885 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) CS348_19955 ENOG4105M5B (LipO)protein CS348_19960 ENOG4105C54 Major Facilitator superfamily CS348_19965 ENOG4105WQV ferredoxin-like protein CS348_19970 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase CS348_20020 ENOG4108XNW Transcriptional activatory protein CaiF CS348_20025 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain CS348_20030 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain CS348_20055 ENOG4105CHY citrate lyase, alpha CS348_20060 ENOG4105CI0 Citrate lyase CS348_20070 ENOG4105DUA (citrate (pro-3S)-lyase ligase CS348_20085 ENOG4107QSA Oxaloacetate decarboxylase CS348_20090 ENOG4105D9Q decarboxylase (Beta subunit) CS348_20095 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism CS348_20100 ENOG4106YYS transcriptional regulatory protein CS348_20120 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase CS348_20135 ENOG4105DTN riboflavin biosynthesis protein ribF CS348_20140 ENOG410647N response to DNA damage stimulus CS348_20160 ENOG41063Z6 transcriptional regulator, lysR family CS348_20180 ENOG4105C4X radical SAM domain protein CS348_20185 ENOG41061MV Arylsulfatase CS348_20195 ENOG4105CGH 5'-nucleotidase CS348_20210 ENOG4105DQS Transcriptional regulator CS348_20230 ENOG4106PH7 chaperone CS348_20245 ENOG4105MHR Fimbrial protein CS348_20250 ENOG4105CW0 outer membrane usher protein CS348_20255 ENOG4108AF8 Chaperone CS348_20315 ENOG4108QUJ UPF0174 protein YaaW CS348_20320 ENOG4106HK8 GPR1 FUN34 yaaH family protein CS348_20325 ENOG4108RIR Molybdenum cofactor biosynthesis protein CS348_20335 ENOG4105BZG amino acid carrier protein CS348_20345 ENOG4105D98 threonine synthase CS348_20355 ENOG4105CFH Aspartokinase CS348_20365 ENOG4106FVC RNA methyltransferase CS348_20370 ENOG410759A CS348_20375 ENOG41065U4 response regulator CS348_20385 ENOG4108PNB DNA-binding transcriptional regulator CS348_20395 ENOG4108VCD Chaperone CS348_20415 ENOG4105CT7 inner membrane cred family protein CS348_20420 ENOG4105EB3 Histidine kinase CS348_20425 ENOG4105E3W Two component transcriptional regulator (Winged helix family CS348_20430 ENOG4108RH0 Crea protein CS348_20435 ENOG4105UEI Transcriptional Regulator AraC Family CS348_20445 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) CS348_20455 ENOG4107SC1 transglycosylase CS348_20465 ENOG4105C5H ABC transporter CS348_20470 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase CS348_20475 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) CS348_20480 ENOG4105EAC phosphoserine phosphatase CS348_20490 ENOG41062Z9 Membrane CS348_20505 ENOG4105UMR response to DNA damage stimulus CS348_20510 ENOG4108S1B Periplasmic chaperone protein CS348_20520 ENOG4105UZW Tail fiber assembly protein CS348_20630 ENOG4108QUU Morphogenesis Protein CS348_20640 ENOG4105CF2 Mu-like prophage FluMu protein GP28 CS348_20805 ENOG4105G0K glycine radical enzyme YjjI family CS348_20810 ENOG41076CZ activating enzyme CS348_20815 ENOG4105EYA deoxyribonuclease CS348_20820 ENOG4108NRW Phospholipase, patatin family CS348_20830 ENOG4105K3G Periplasmic Protein CS348_20840 ENOG4105PAD Hydrolase CS348_20845 ENOG4105KEG ribosomal-protein-alanine acetyltransferase CS348_20850 ENOG4108WPU DNA polymerase III subunit psi CS348_20875 ENOG4105YBH Protein of unknown function (DUF1435) CS348_20880 ENOG4105BZU Histidine kinase CS348_20885 ENOG4108819 ferric iron reductase CS348_20890 ENOG4108UIN ybak prolyl-trna synthetase associated region CS348_20895 ENOG4108T94 DNA-binding transcriptional activator BglJ CS348_20900 ENOG4108N8T regulatoR CS348_20905 ENOG4105DWK Membrane CS348_20920 ENOG4106CVF DNA replication protein CS348_20925 ENOG4105RI1 glycoprotein receptor CS348_20935 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) CS348_20940 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) CS348_20945 ENOG4105F3R pts system mannose fructose sorbose family iid CS348_20950 ENOG4105ETZ PTS System CS348_20955 ENOG4108IQ3 PTS system CS348_20970 ENOG4105C8Q Methyl-accepting chemotaxis CS348_20975 ENOG4105D22 carbon starvation protein CS348_20980 ENOG4105VCD cytoplasmic protein CS348_20985 ENOG4105CKI cobalamin synthesis protein CS348_20990 ENOG41063TF transcriptional regulator (AraC CS348_20995 ENOG4105E82 cytochrome subunit of dehydrogenase CS348_21000 ENOG4108HFV CS348_21015 ENOG4105C26 Dehydrogenase CS348_21020 ENOG4105DNE Transposase CS348_21025 ENOG41083G8 Multidrug resistance protein MdtM CS348_21030 ENOG4106BRA Membrane CS348_21035 ENOG4105CBP Major Facilitator CS348_21040 ENOG41074DU domain protein CS348_21045 ENOG4108P2H Inner membrane protein YjiG CS348_21050 ENOG4105DYB Isoaspartyl dipeptidase CS348_21055 ENOG4107YNJ LysR family Transcriptional regulator CS348_21080 ENOG4105C6F GntR Family Transcriptional Regulator CS348_21105 ENOG4105KZM cytoplasmic protein CS348_21115 ENOG4105YCT UPF0386 protein CS348_21120 ENOG4105DTA methyltransferase CS348_21165 ENOG4105DQ4 alcohol dehydrogenase CS348_21170 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family CS348_21175 ENOG4105CPQ Dehydrogenase CS348_21180 ENOG4105CHR reductase CS348_21185 ENOG4105C6Z Gluconate CS348_21190 ENOG4105K2J Transcriptional regulator CS348_21195 ENOG4108K5H permease YjgP YjgQ family protein CS348_21200 ENOG4108M8S permease YjgP YjgQ family protein CS348_21220 ENOG4105MYG DNA polymerase iii, chi subunit CS348_21225 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) CS348_21230 ENOG4108M3P Membrane CS348_21235 ENOG4108MJ3 acetyltransferase CS348_21245 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase CS348_21250 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) CS348_21255 ENOG4105DBV ornithine carbamoyltransferase CS348_21260 ENOG4105XEP YhcH YjgK YiaL family protein CS348_21275 ENOG4105C5B carbamate kinase CS348_21280 ENOG4105DBV ornithine carbamoyltransferase CS348_21285 ENOG4105CSX c4-dicarboxylate anaerobic carrier CS348_21290 ENOG410682Y Regulates arginine biosynthesis genes (By similarity) CS348_21300 ENOG41077AM PyrBI operon attenuator CS348_21315 ENOG4105KME endoribonuclease L-psp CS348_21330 ENOG4105D4X repressor CS348_21335 ENOG4105C5Y PTS System CS348_21340 ENOG4105CG3 alpha amylase, catalytic region CS348_21345 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase CS348_21350 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) CS348_21355 ENOG4105K4U addiction module toxin, RelE StbE family CS348_21365 ENOG4105EMD TRANSCRIPTIONal CS348_21380 ENOG41069H0 dihydroorotase EC 3.5.2.3 CS348_21410 ENOG4108XVM Cytochrome b(562) CS348_21415 ENOG4105CMS peptidase U62, modulator of DNA gyrase CS348_21425 ENOG4105F0H myo-inositol catabolism protein CS348_21435 ENOG4105IE8 Alpha-ketoglutarate permease CS348_21440 ENOG4105CK5 oxidoreductase CS348_21445 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) CS348_21450 ENOG4105D7K pfkb domain protein CS348_21460 ENOG4107VG4 Xylose isomerase domain protein TIM barrel CS348_21465 ENOG4108MYR Secreted protein CS348_21490 ENOG4105C26 Dehydrogenase CS348_21495 ENOG4105DH8 myo-inositol catabolism CS348_21500 ENOG4107QNK )-transporter CS348_21510 ENOG4107QNK )-transporter CS348_21515 ENOG4105CHC glucokinase (EC 2.7.1.2) CS348_21525 ENOG4105DFU Cell wall formation (By similarity) CS348_21535 ENOG4105F0N pyrophosphate phospho-hydrolase CS348_21540 ENOG41069H0 dihydroorotase EC 3.5.2.3 CS348_21545 ENOG4105DJB Major Facilitator Superfamily CS348_21550 ENOG4108ZHD aig2 family CS348_21570 ENOG4105C37 (CBS) domain CS348_21575 ENOG41061GZ Protein of unknown function (DUF1107) CS348_21585 ENOG4108UUE Transcriptional regulator CS348_21590 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase CS348_21600 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic CS348_21605 ENOG4105KVH Transcriptional regulator CS348_21610 ENOG4105ECR NmrA family CS348_21615 ENOG4105DXC membrane CS348_21630 ENOG4108V1T peptidylprolyl cis-trans isomerase CS348_21635 ENOG4105FHY Opacity-associated protein A CS348_21650 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) CS348_21660 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) CS348_21670 ENOG4105KIT UPF0379 protein yjfY CS348_21675 ENOG4105R3P Inner membrane protein yagU CS348_21705 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC CS348_21720 ENOG4108MXZ Esterase CS348_21725 ENOG4105WSB biofilm stress and motility protein A CS348_21730 ENOG4105S17 UPF0379 protein yjfN CS348_21735 ENOG4105CSU acyl-Coa dehydrogenase CS348_21740 ENOG4106032 Glutathionylspermidine synthase CS348_21745 ENOG4108KXT Conserved Protein CS348_21750 ENOG4105Z6B inner membrane protein yjfl CS348_21755 ENOG4107VNS Protein of unknown function (DUF2491) CS348_21760 ENOG4108P9J Phage shock protein A CS348_21765 ENOG4105FUX Conserved Protein CS348_21770 ENOG4105C2N RNA methyltransferase TrmH family group 3 CS348_21775 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) CS348_21800 ENOG4105EPW hflc protein CS348_21805 ENOG4107QJR hflk protein CS348_21810 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) CS348_21830 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase CS348_21835 ENOG4105K8N protein family UPF0079, ATPase CS348_21840 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) CS348_21845 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) CS348_21865 ENOG4106TNF Periplasmic binding protein CS348_21885 ENOG4105EGS Mechanosensitive ion channel CS348_21890 ENOG4107SC7 Inner membrane transporter yjeM CS348_21900 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) CS348_21905 ENOG4105E33 succinate dehydrogenase CS348_21925 ENOG4105KPY Small multidrug resistance protein CS348_21935 ENOG4106BSU Entericidin B CS348_21950 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein CS348_21955 ENOG4105MTB Uncharacterized protein YjeJ CS348_21960 ENOG4108ZVF (LipO)protein CS348_21975 ENOG4105DVH amino acid CS348_21980 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 CS348_21985 ENOG4108IJ0 Aspartate ammonia-lyase CS348_21990 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CS348_22005 ENOG4108SIC Transcriptional regulator CS348_22020 ENOG4105SBG acid phosphatase CS348_22110 ENOG41068CG regulatoR CS348_22115 ENOG41080WI Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity) CS348_22120 ENOG4108ZK4 sdia-regulated domain-containing protein CS348_22130 ENOG4108NEM leader-binding protein dmsD CS348_22135 ENOG4107KGK dmso reductase anchor subunit CS348_22140 ENOG4105QAX Iron-sulfur CS348_22145 ENOG4107QY8 reductase CS348_22150 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism CS348_22155 ENOG4108MRH transcriptional regulatory protein CS348_22165 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CS348_22170 ENOG4107GFK fumarate CS348_22175 ENOG4105CT4 transporter CS348_22180 ENOG4105F8D glycoside hydrolase family 4 CS348_22185 ENOG4108K2B transcriptional regulator CS348_22190 ENOG4105CXN decarboxylase CS348_22195 ENOG4106ZGR Transcriptional regulator CS348_22200 ENOG4105D5Q Arginine ornithine antiporter CS348_22205 ENOG4105DIJ Phosphoethanolamine transferase CS348_22210 ENOG4105XJC Two component transcriptional regulator (Winged helix family CS348_22215 ENOG4105ECM Sensor protein basS pmrB CS348_22225 ENOG4105CSH Transporter CS348_22230 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA CS348_22235 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase CS348_22240 ENOG410870W N-acetyltransferase CS348_22255 ENOG41082ND Uncharacterized protein yjcO CS348_22260 ENOG4105CK2 sodium dicarboxylate symporter CS348_22265 ENOG4108W0S formate-dependent nitrite reductase complex CS348_22275 ENOG4108QKW cytochrome c-type biogenesis protein CS348_22280 ENOG4105DVI reductase, NrfD CS348_22285 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein CS348_22290 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit CS348_22305 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) CS348_22310 ENOG41062QD Membrane CS348_22320 ENOG41067MG lrgb family CS348_22330 ENOG4105CMU LysR family (Transcriptional regulator CS348_22335 ENOG4105EEQ Na H antiporter CS348_22345 ENOG4105C7N Xanthine uracil vitamin C permease CS348_22360 ENOG4108Z4X TRANSCRIPTIONal CS348_22365 ENOG4108W3Q Transcriptional regulator CS348_22370 ENOG4108M8H domain protein CS348_22375 ENOG4105PMV Membrane CS348_22415 ENOG4108UUM single-stranded DNA-binding protein CS348_22425 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) CS348_22440 ENOG4105MSB protein, conserved in bacteria CS348_22445 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme CS348_22450 ENOG4105F0S class B acid phosphatase CS348_22455 ENOG4105CGF Aromatic amino acid aminotransferase CS348_22460 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) CS348_22465 ENOG4105CDU Replicative dna helicase CS348_22470 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein CS348_22475 ENOG4105P4Z Phage shock protein G CS348_22480 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) CS348_22490 ENOG4105MYN Zinc uptake regulation protein CS348_22495 ENOG4105VDW Csbd family CS348_22505 ENOG4107R73 Mate efflux family protein CS348_22515 ENOG41080IJ Diacylglycerol kinase CS348_22535 ENOG4107W52 maltose operon periplasmic protein CS348_22550 ENOG4107FKK extracellular solute-binding protein family 1 CS348_22555 ENOG4105D56 permease protein CS348_22560 ENOG4105EG2 ABC transporter, permease CS348_22565 ENOG4107QNK )-transporter CS348_22575 ENOG4105E3R (LipO)protein CS348_22580 ENOG4108Q9C Periplasmic Protein CS348_22585 ENOG4108MDC (LipO)protein CS348_22600 ENOG4105CFH Aspartokinase CS348_22620 ENOG4108KP7 hydrolase CS348_22625 ENOG4105E98 transcriptional regulator DeoR family CS348_22635 ENOG4108ZR5 Conserved Protein CS348_22640 ENOG4105FE9 pseudouridine synthase CS348_22645 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme CS348_22660 ENOG4105EAM Na Pi-cotransporter CS348_22665 ENOG4105C3R Methionine synthase CS348_22670 ENOG41069M3 Transcriptional regulator CS348_22685 ENOG4108I9X Isocitrate lyase CS348_22690 ENOG4107QP3 malate synthase g CS348_22700 ENOG4105K5X acetyltransferase CS348_22730 ENOG4105C12 Phosphoribosylglycinamide synthetase CS348_22735 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CS348_22740 ENOG4105BZU Histidine kinase CS348_22750 ENOG4108T8B Protein of unknown function (DUF1481) CS348_22755 ENOG4105K70 DNA-binding protein CS348_22760 ENOG4105R2J Conserved Protein CS348_22785 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) CS348_22795 ENOG4105D06 uba thif-type nad fad binding protein CS348_22800 ENOG4105WHD thiamine biosynthesis protein ThiS CS348_22810 ENOG4105D41 biosynthesis protein thiH CS348_22840 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) CS348_22865 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) CS348_22870 ENOG4105PM1 preprotein translocase subunit SecE CS348_22875 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) CS348_22915 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase CS348_22920 ENOG4105D4A Cell wall formation (By similarity) CS348_22970 ENOG4108Y73 Membrane CS348_22990 ENOG4105C5Q Transcriptional regulator CS348_23030 ENOG4105DIJ Phosphoethanolamine transferase CS348_23035 ENOG4106R3P AraC family transcriptional regulator CS348_23045 ENOG4105DCT glycerol dehydrogenase CS348_23055 ENOG4105SYT Methylenetetrahydrofolate reductase CS348_23060 ENOG4105CGH 5'-nucleotidase CS348_23080 ENOG4105CFH Aspartokinase CS348_23085 ENOG4105C28 cystathionine CS348_23095 ENOG4108MR7 Arylsulfotransferase CS348_23110 ENOG4105C25 Primosomal protein n' CS348_23115 ENOG4105ETE Transcriptional regulator (LacI family CS348_23120 ENOG41063M6 Cell Division Protein CS348_23135 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase CS348_23145 ENOG4105N4M Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity) CS348_23150 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) CS348_23160 ENOG4105CBT Fructose-1,6-bisphosphatase CS348_23165 ENOG4105DP0 ferredoxin-NADP reductase CS348_23170 ENOG4108VTS Membrane CS348_23175 ENOG4105EBK exported protein CS348_23200 ENOG4105D4B ABC, transporter CS348_23225 ENOG4107RYS Autoinducer-2 (AI-2) kinase CS348_23255 ENOG4105D7K pfkb domain protein CS348_23260 ENOG4105CT4 transporter CS348_23270 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein CS348_23290 ENOG4105ZTC transcriptional activator, Ogr delta CS348_23330 ENOG4105UZW Tail fiber assembly protein CS348_23335 ENOG4108X9F tail fiber protein CS348_23420 ENOG4105ED4 portal protein CS348_23440 ENOG4105VZ1 Replication Protein CS348_23480 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CS348_23485 ENOG4105FMW periplasmic CS348_23490 ENOG4105E3W Two component transcriptional regulator (Winged helix family CS348_23495 ENOG4105E0F Histidine kinase CS348_23505 ENOG4108RPX mosc domain containing protein CS348_23510 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CS348_23515 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit CS348_23520 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter CS348_23525 ENOG4105CG6 trap dicarboxylate transporter dctm subunit CS348_23530 ENOG4108QGT oligogalacturonate-specific porin CS348_23555 ENOG4105DKG l-rhamnose isomerase CS348_23565 ENOG4105C0A alcohol dehydrogenase CS348_23580 ENOG4108UMN azlc family CS348_23590 ENOG4108V87 frv operon regulatory protein CS348_23600 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CS348_23605 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CS348_23610 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein CS348_23615 ENOG4108MG3 formate dehydrogenase CS348_23630 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system CS348_23640 ENOG4105RVE Uncharacterized protein conserved in bacteria (DUF2136) CS348_23645 ENOG4108Z3N Transcriptional regulator CS348_23650 ENOG4105SUU thioesterase domain CS348_23665 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 CS348_23670 ENOG4105E98 transcriptional regulator DeoR family CS348_23675 ENOG4108MGF sugar kinase CS348_23680 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase CS348_23685 ENOG4105D2M Aldolase CS348_23690 ENOG4107QKS N-acylglucosamine 2-epimerase CS348_23695 ENOG4107WI4 Aldose-1-epimerase CS348_23700 ENOG4105CJQ hydrolase, family 31 CS348_23705 ENOG4105CT4 transporter CS348_23710 ENOG4105CT4 transporter CS348_23715 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is CS348_23745 ENOG4108K4B hydrolase CS348_23760 ENOG4105C5F glutamine synthetase CS348_23770 ENOG4105CUX Signal transduction histidine kinase CS348_23775 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CS348_23780 ENOG4106FIY CS348_23785 ENOG4105D4P Coproporphyrinogen iii oxidase CS348_23805 ENOG4105C2M dna polymerase I CS348_23815 ENOG4106HNH Acyl-transferase CS348_23830 ENOG4105PC1 Conserved Protein CS348_23835 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) CS348_23840 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b CS348_23875 ENOG4108RR8 protoporphyrinogen oxidase CS348_23880 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) CS348_23885 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein CS348_23905 ENOG4108MR7 Arylsulfotransferase CS348_23910 ENOG4107QK7 reductase CS348_23915 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) CS348_23920 ENOG4105MDZ Transcriptional activator rfaH CS348_23925 ENOG4105F8V Hydrolase, tatD family CS348_23930 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) CS348_23940 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) CS348_23950 ENOG4105JC1 sterol-binding domain protein CS348_23960 ENOG4105CGY Dna recombination protein CS348_23965 ENOG4108I5U Uridine phosphorylase CS348_23970 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) CS348_23975 ENOG4105C4X radical SAM domain protein CS348_23985 ENOG4105DZ2 Transcriptional regulator CS348_23990 ENOG4105EMK carboxylate amino acid amine transporter CS348_23995 ENOG4105DQF Hydrolase CS348_24000 ENOG4108EUD Lysophospholipase CS348_24005 ENOG410829K Lysine exporter protein (Lyse ygga) CS348_24010 ENOG4105CCF Lysine exporter protein (Lyse ygga) CS348_24015 ENOG4105C9U ATP-dependent DNA helicase RecQ CS348_24020 ENOG4105HDD phospholipase CS348_24025 ENOG4108VUY thioesterase Superfamily protein CS348_24030 ENOG4105FR1 rard protein CS348_24055 ENOG4105C4R Atp-dependent dna helicase CS348_24060 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant CS348_24065 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CS348_24070 ENOG4105CT0 Protein of unknown function, DUF484 CS348_24080 ENOG4105S7Z (LipO)protein CS348_24100 ENOG4107T0K Adenylate cyclase CS348_24110 ENOG41076E6 Uroporphyrinogen-III Synthase CS348_24115 ENOG4105ECF c-methyltransferase CS348_24120 ENOG410601J HemY protein CS348_24145 ENOG4105C85 amino acid CS348_24165 ENOG4105EGZ biosynthesis protein CS348_24170 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase CS348_24175 ENOG4108WJ1 acetyltransferase CS348_24180 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) CS348_24185 ENOG4105C1B dTDP-glucose 4-6-dehydratase CS348_24190 ENOG4108IJ1 Dehydrogenase CS348_24195 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase CS348_24200 ENOG4105SFE lipopolysaccharide biosynthesis protein CS348_24205 ENOG4105ESV Glycosyl transferase, family 4 CS348_24215 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) CS348_24220 ENOG4105K63 Thioredoxin CS348_24235 ENOG4105C4R Atp-dependent dna helicase CS348_24240 ENOG4106Z1T Nicotinamide Mononucleotide Transporter CS348_24245 ENOG4107SXA Phosphorylase CS348_24255 ENOG4105KQ5 peptidylprolyl cis-trans isomerase CS348_24265 ENOG4105EMY transcriptional regulator CS348_24285 ENOG4105C7B Threonine dehydratase CS348_24295 ENOG4105CM2 brancheD-chain amino acid aminotransferase CS348_24300 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit CS348_24315 ENOG4105C0P Mg chelatase subunit ChlI CS348_24360 ENOG4107EJG GntR family transcriptional regulator CS348_24365 ENOG4105C0R drug resistance transporter emrb qaca subfamily CS348_24370 ENOG4105ETE Transcriptional regulator (LacI family CS348_24375 ENOG4108RVA ribokinase CS348_24380 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CS348_24385 ENOG4105CNN ABC, transporter CS348_24420 ENOG4108VVK transcriptional Regulator, AsnC CS348_24425 ENOG4105QTB Flavodoxin CS348_24440 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation CS348_24450 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) CS348_24480 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) CS348_24520 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) CS348_24525 ENOG4105F9E Shikimate 5-dehydrogenase CS348_24530 ENOG4105DM4 PTS System CS348_24535 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) CS348_24540 ENOG4105C8U phosphate abc transporter CS348_24545 ENOG4105E2Z phosphate ABC transporter (Permease CS348_24560 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 CS348_24565 ENOG4105C7N Xanthine uracil vitamin C permease CS348_24570 ENOG4108YYH Nadph-dependent fmn reductase CS348_24575 ENOG4105E8Q phosphopantetheinyl transferase CS348_24615 ENOG4105ECQ AraC Family Transcriptional Regulator CS348_24625 ENOG4106JVB Replication Protein CS348_24630 ENOG4108MBX Secretion Protein CS348_24635 ENOG4108JJA ABC, transporter CS348_24730 ENOG41073YN Protein of unknown function (DUF1380) CS348_24765 ENOG4105MPK DNA polymerase III subunit theta CS348_24785 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) CS348_24830 ENOG41074AV Hok/gef family CS348_24840 ENOG41074AV Hok/gef family CS348_24845 ENOG4105CW0 outer membrane usher protein CS348_24850 ENOG4108AF8 Chaperone CS348_24870 ENOG4108J1Q CS348_24890 ENOG4105C8Q Methyl-accepting chemotaxis CS348_24900 ENOG4105GTN ParB Domain Protein Nuclease CS348_24905 ENOG4105BZV Phosphoadenosine phosphosulfate reductase CS348_24940 ENOG4107EFR Flavocytochrome c CS348_24945 ENOG4105BZU Histidine kinase CS348_25115 ENOG4105K5T PilT protein CS348_25130 ENOG4107QHF type ii secretion system protein e CS348_25210 ENOG4105UYK outer membrane protein a CS348_25280 ENOG41090KG Inner membrane protein YqjE CS348_25455 ENOG4108UUM single-stranded DNA-binding protein CS348_25545 ENOG4106JVB Replication Protein CS348_25565 ENOG4105PPN plasmid maintenance protein, CcdB CS348_25570 ENOG4105XY2 plasmid maintenance protein CcdA CS348_25605 ENOG4105D3F AraC Family Transcriptional Regulator CS348_25620 ENOG4108JJ6 Type I secretion system ATPase CS348_25630 ENOG4105DFG type I secretion outer membrane protein CS348_25635 ENOG4108J1Q CS348_25645 ENOG4105WPN DNA integration recombination invertion protein CS348_25660 ENOG4105DQ5 transport system permease protein CS348_25670 ENOG4105E0A ABC, transporter CS348_25720 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase CS348_25725 ENOG4108MJ5 VirK protein CS348_25730 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) CS348_25745 ENOG4108RS6 transposase CS348_25755 ENOG4108J1Q CS348_25775 ENOG41073DY may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity) CS348_25785 ENOG4106CQM replication CS348_25795 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity)