locus-tag	class	description
E2R47_00085	COG1192	Involved in chromosome partitioning
E2R47_00120	COG3039	Transposase
E2R47_00330	COG4245	von Willebrand factor, type A
E2R47_00335	COG4245	von Willebrand factor, type A
E2R47_00365	COG1358	cellular component organization or biogenesis
E2R47_00465	COG3550	peptidyl-serine autophosphorylation
E2R47_00515	COG3316	Transposase and inactivated derivatives
E2R47_00535	COG3316	Transposase and inactivated derivatives
E2R47_00610	COG3316	Transposase and inactivated derivatives
E2R47_00660	COG3316	Transposase and inactivated derivatives
E2R47_00695	COG0697	spore germination
E2R47_00810	COG4221	oxidoreductase activity
E2R47_00820	COG3316	Transposase and inactivated derivatives
E2R47_00840	COG3316	Transposase and inactivated derivatives
E2R47_00855	COG3300	MHYT domain
E2R47_00855	COG5001	Diguanylate cyclase
E2R47_00915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
E2R47_00945	COG3316	Transposase and inactivated derivatives
E2R47_00965	COG1660	Displays ATPase and GTPase activities
E2R47_00980	COG3316	Transposase and inactivated derivatives
E2R47_00995	COG0768	penicillin binding
E2R47_01020	COG3039	Transposase
E2R47_01075	COG3316	Transposase and inactivated derivatives
E2R47_01100	COG3316	Transposase and inactivated derivatives
E2R47_01125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E2R47_01125	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E2R47_01145	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E2R47_01505	COG2890	protein-(glutamine-N5) methyltransferase activity
E2R47_01565	COG2433	Pfam Transposase IS66
E2R47_01570	COG3436	PFAM IS66 Orf2 family protein
E2R47_01630	COG0187	DNA topoisomerase II activity
E2R47_01645	COG0561	phosphatase activity
E2R47_01665	COG2198	Histidine kinase
E2R47_01665	COG0784	Response regulator, receiver
E2R47_01665	COG2205	protein histidine kinase activity
E2R47_01670	COG1879	ABC-type sugar transport system periplasmic component
E2R47_01675	COG0745	RESPONSE REGULATOR receiver
E2R47_01680	COG3005	denitrification pathway
E2R47_01695	COG1858	cytochrome C peroxidase
E2R47_01705	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E2R47_01710	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E2R47_01715	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E2R47_01725	COG1138	Cytochrome C-type biogenesis protein
E2R47_01735	COG4235	cytochrome complex assembly
E2R47_01735	COG3088	subunit of a heme lyase
E2R47_01740	COG0823	Involved in the tonB-independent uptake of proteins
E2R47_01745	COG5645	(Lipo)protein
E2R47_01765	COG2149	membrane
E2R47_01775	COG0641	radical SAM
E2R47_01785	COG2610	gluconate transmembrane transporter activity
E2R47_01790	COG0583	DNA-binding transcription factor activity
E2R47_01800	COG2814	Major facilitator Superfamily
E2R47_01825	COG0028	Belongs to the TPP enzyme family
E2R47_01830	COG0440	acetolactate synthase activity
E2R47_01835	COG1349	DNA-binding transcription factor activity
E2R47_01840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E2R47_01845	COG0738	Major facilitator superfamily
E2R47_01890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E2R47_01890	COG3711	transcriptional antiterminator
E2R47_01895	COG3414	Phosphotransferase system galactitol-specific IIB component
E2R47_01900	COG3775	system Galactitol-specific IIC component
E2R47_01935	COG2723	6-phospho-beta-galactosidase activity
E2R47_01955	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E2R47_01955	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E2R47_01960	COG3715	PTS system
E2R47_01965	COG3716	PTS system mannose fructose sorbose family IID component
E2R47_01980	COG5464	transposase or invertase
E2R47_01990	COG1285	pathogenesis
E2R47_02010	COG1335	isochorismatase
E2R47_02020	COG3710	Transcriptional regulator
E2R47_02035	COG2771	luxR family
E2R47_02055	COG3121	Chaperone
E2R47_02060	COG3188	usher protein
E2R47_02070	COG3539	Fimbrial protein
E2R47_02080	COG3539	Fimbrial protein
E2R47_02095	COG2211	Major facilitator Superfamily
E2R47_02100	COG1501	Belongs to the glycosyl hydrolase 31 family
E2R47_02105	COG2982	Protein involved in outer membrane biogenesis
E2R47_02110	COG2233	PERMEase
E2R47_02115	COG0786	glutamate:sodium symporter activity
E2R47_02125	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
E2R47_02130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E2R47_02135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E2R47_02155	COG2860	membrane
E2R47_02170	COG0583	DNA-binding transcription factor activity
E2R47_02175	COG1561	YicC-like family, N-terminal region
E2R47_02200	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E2R47_02230	COG1519	Transferase
E2R47_02235	COG0859	PFAM glycosyl transferase family 9
E2R47_02240	COG0438	transferase activity, transferring glycosyl groups
E2R47_02320	COG1216	Glycosyl transferase, family 2
E2R47_02325	COG2861	carbohydrate metabolic process
E2R47_02330	COG4942	peptidase
E2R47_02340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E2R47_02345	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E2R47_02365	COG2271	Major facilitator Superfamily
E2R47_02375	COG1609	Transcriptional regulator
E2R47_02380	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
E2R47_02390	COG2186	Transcriptional regulator
E2R47_02420	COG3722	fumarate hydratase activity
E2R47_02430	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
E2R47_02430	COG2213	PTS system mannitol-specific
E2R47_02445	COG1566	PFAM secretion protein HlyD family protein
E2R47_02450	COG0625	glutathione transferase activity
E2R47_02460	COG3276	selenocysteine insertion sequence binding
E2R47_02465	COG1940	carbohydrate kinase activity
E2R47_02470	COG1012	belongs to the aldehyde dehydrogenase family
E2R47_02490	COG0235	Class ii aldolase
E2R47_02495	COG3623	hexulose-6-phosphate isomerase
E2R47_02500	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
E2R47_02505	COG1070	Carbohydrate kinase
E2R47_02510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E2R47_02515	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E2R47_02520	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E2R47_02530	COG2731	YhcH YjgK YiaL family protein
E2R47_02540	COG1414	Transcriptional regulator
E2R47_02545	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E2R47_02550	COG3977	Valine--pyruvate aminotransferase
E2R47_02555	COG0366	Alpha amylase catalytic
E2R47_02560	COG2992	FlgJ-related protein
E2R47_02565	COG1609	Transcriptional regulator
E2R47_02565	COG2207	Transcriptional regulator
E2R47_02580	COG1070	Carbohydrate kinase
E2R47_02585	COG4682	membrane
E2R47_02590	COG3274	enterobacterial common antigen metabolic process
E2R47_02615	COG2801	Transposase and inactivated derivatives
E2R47_02620	COG2271	Major facilitator Superfamily
E2R47_02630	COG0583	DNA-binding transcription factor activity
E2R47_02635	COG1280	lysine exporter protein (LysE YggA)
E2R47_02655	COG1278	Cold shock
E2R47_02660	COG2944	sequence-specific DNA binding
E2R47_02675	COG2885	chlorophyll binding
E2R47_02680	COG0243	molybdopterin cofactor binding
E2R47_02685	COG0456	acetyltransferase
E2R47_02690	COG2818	Glycosylase
E2R47_02695	COG5571	outer membrane autotransporter
E2R47_02715	COG1609	Transcriptional regulator
E2R47_02730	COG0747	negative chemotaxis
E2R47_02735	COG0601	transmembrane transport
E2R47_02740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E2R47_02745	COG0444	Belongs to the ABC transporter superfamily
E2R47_02750	COG4608	Belongs to the ABC transporter superfamily
E2R47_02755	COG0814	amino acid
E2R47_02795	COG1215	transferase activity, transferring glycosyl groups
E2R47_02820	COG2200	EAL domain
E2R47_02820	COG2199	diguanylate cyclase activity
E2R47_02835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E2R47_02840	COG2200	EAL domain
E2R47_02845	COG2982	Protein involved in outer membrane biogenesis
E2R47_02850	COG0477	Major facilitator Superfamily
E2R47_02855	COG1295	ribonuclease BN
E2R47_02860	COG0583	DNA-binding transcription factor activity
E2R47_02865	COG2197	response regulator
E2R47_02885	COG2188	Transcriptional regulator
E2R47_02890	COG2222	sugar isomerase
E2R47_02895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E2R47_02900	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E2R47_02910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E2R47_02915	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
E2R47_02920	COG0671	phosphoesterase, PA-phosphatase related
E2R47_02950	COG0306	phosphate transporter
E2R47_02955	COG2081	HI0933 family
E2R47_02960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E2R47_02965	COG1129	ABC transporter
E2R47_02965	COG0842	Transport permease protein
E2R47_02970	COG0842	Transport permease protein
E2R47_02980	COG2091	lysine biosynthetic process via aminoadipic acid
E2R47_02985	COG0628	permease
E2R47_03000	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E2R47_03020	COG3714	YhhN family
E2R47_03030	COG3776	membrane
E2R47_03035	COG0742	ribosomal rna small subunit methyltransferase
E2R47_03040	COG0552	protein localization to endoplasmic reticulum
E2R47_03045	COG2884	Cell division ATP-binding protein ftsE
E2R47_03050	COG2177	Part of the ABC transporter FtsEX involved in
E2R47_03075	COG0683	leucine binding
E2R47_03080	COG0559	Belongs to the binding-protein-dependent transport system permease family
E2R47_03090	COG0411	ABC transporter
E2R47_03095	COG0410	ABC transporter
E2R47_03110	COG1653	transport
E2R47_03130	COG0584	glycerophosphoryl diester phosphodiesterase
E2R47_03140	COG0405	Gamma-glutamyltransferase
E2R47_03145	COG1735	metal-dependent hydrolase with the TIM-barrel fold
E2R47_03160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E2R47_03165	COG1247	-acetyltransferase
E2R47_03170	COG0673	inositol 2-dehydrogenase activity
E2R47_03175	COG1741	Belongs to the pirin family
E2R47_03180	COG1609	Transcriptional regulator
E2R47_03185	COG3265	gluconokinase activity
E2R47_03190	COG2610	gluconate transmembrane transporter activity
E2R47_03195	COG2095	MarC family integral membrane protein
E2R47_03200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E2R47_03205	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
E2R47_03225	COG0058	SHG alpha-glucan phosphorylase activity
E2R47_03230	COG1414	Transcriptional regulator
E2R47_03235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E2R47_03240	COG0129	dihydroxy-acid dehydratase activity
E2R47_03250	COG0371	Dehydrogenase
E2R47_03265	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E2R47_03275	COG0705	Rhomboid family
E2R47_03280	COG1349	DNA-binding transcription factor activity
E2R47_03285	COG4650	regulator
E2R47_03295	COG1690	Belongs to the RtcB family
E2R47_03315	COG0058	SHG alpha-glucan phosphorylase activity
E2R47_03320	COG1640	4-alpha-glucanotransferase
E2R47_03325	COG2610	gluconate transmembrane transporter activity
E2R47_03345	COG5464	transposase or invertase
E2R47_03360	COG1918	ferrous iron import across plasma membrane
E2R47_03365	COG2183	response to ionizing radiation
E2R47_03370	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E2R47_03375	COG0745	RESPONSE REGULATOR receiver
E2R47_03390	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E2R47_03400	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E2R47_03405	COG1011	Hydrolase
E2R47_03415	COG0494	nUDIX hydrolase
E2R47_03420	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
E2R47_03425	COG4972	Pilus assembly protein
E2R47_03430	COG3166	PFAM Fimbrial assembly family protein
E2R47_03445	COG4796	Type ii and iii secretion system protein
E2R47_03465	COG3266	domain, Protein
E2R47_03470	COG0338	D12 class N6 adenine-specific DNA methyltransferase
E2R47_03475	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E2R47_03485	COG0180	Tryptophanyl-tRNA synthetase
E2R47_03510	COG2146	nitrite reductase [NAD(P)H] activity
E2R47_03515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E2R47_03550	COG1289	transmembrane transporter activity
E2R47_03560	COG1765	OsmC-like protein
E2R47_03565	COG3954	Phosphoribulokinase
E2R47_03575	COG0429	hydrolase of the alpha beta-hydrolase fold
E2R47_03590	COG0488	(ABC) transporter
E2R47_03605	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
E2R47_03610	COG1047	Peptidyl-prolyl cis-trans
E2R47_03620	COG0545	Peptidyl-prolyl cis-trans isomerase
E2R47_03625	COG2964	Protein conserved in bacteria
E2R47_03665	COG2906	2 iron, 2 sulfur cluster binding
E2R47_03680	COG0051	transcription antitermination factor activity, RNA binding
E2R47_03735	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
E2R47_03785	COG0201	protein transport
E2R47_03825	COG0789	Transcriptional regulator
E2R47_03830	COG3036	rescue of stalled ribosome
E2R47_03840	COG0569	domain protein
E2R47_03860	COG0758	DNA mediated transformation
E2R47_03870	COG0551	DNA topoisomerase type I activity
E2R47_03890	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E2R47_03930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E2R47_03935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E2R47_03940	COG1309	transcriptional regulator
E2R47_03955	COG2189	Belongs to the N(4) N(6)-methyltransferase family
E2R47_03965	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E2R47_03975	COG4145	pantothenate transmembrane transporter activity
E2R47_03980	COG3924	membrane
E2R47_03985	COG0439	Biotin carboxylase
E2R47_03990	COG0511	ligase activity, forming carbon-carbon bonds
E2R47_04005	COG0604	alcohol dehydrogenase
E2R47_04010	COG2199	diguanylate cyclase activity
E2R47_04010	COG2200	EAL domain
E2R47_04020	COG1077	Cell shape determining protein MreB Mrl
E2R47_04025	COG1792	Involved in formation and maintenance of cell shape
E2R47_04030	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
E2R47_04040	COG1530	ribonuclease E activity
E2R47_04045	COG3164	Protein of unknown function
E2R47_04050	COG0312	modulator of DNA gyrase
E2R47_04055	COG0583	DNA-binding transcription factor activity
E2R47_04075	COG2732	(Barnase) inhibitor
E2R47_04110	COG0471	metal ion transport
E2R47_04125	COG3630	sodium ion export across plasma membrane
E2R47_04130	COG0511	ligase activity, forming carbon-carbon bonds
E2R47_04130	COG5016	pyruvate
E2R47_04150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E2R47_04155	COG3105	Protein conserved in bacteria
E2R47_04160	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
E2R47_04175	COG0625	glutathione transferase activity
E2R47_04180	COG2969	positive regulation of protein catabolic process
E2R47_04205	COG1940	carbohydrate kinase activity
E2R47_04210	COG2731	YhcH YjgK YiaL family protein
E2R47_04215	COG0402	S-adenosylhomocysteine deaminase activity
E2R47_04220	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
E2R47_04225	COG4804	nuclease activity
E2R47_04230	COG0493	'glutamate synthase
E2R47_04235	COG0069	glutamate synthase activity
E2R47_04235	COG0067	glutamate synthase
E2R47_04235	COG0070	glutamate synthase
E2R47_04240	COG1242	4 iron, 4 sulfur cluster binding
E2R47_04245	COG5002	protein histidine kinase activity
E2R47_04245	COG2198	Histidine kinase
E2R47_04245	COG0784	Response regulator, receiver
E2R47_04250	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
E2R47_04260	COG0515	serine threonine protein kinase
E2R47_04270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E2R47_04280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E2R47_04295	COG1137	ATPase activity
E2R47_04300	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
E2R47_04305	COG3117	lipopolysaccharide transmembrane transporter activity
E2R47_04310	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
E2R47_04320	COG0530	calcium, potassium:sodium antiporter activity
E2R47_04325	COG1127	ABC transporter
E2R47_04330	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E2R47_04335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E2R47_04340	COG2854	intermembrane phospholipid transfer
E2R47_04345	COG3113	response to antibiotic
E2R47_04350	COG5007	Belongs to the BolA IbaG family
E2R47_04360	COG3423	Transcriptional regulator
E2R47_04365	COG0142	geranyltranstransferase activity
E2R47_04380	COG0697	spore germination
E2R47_04390	COG2027	D-alanyl-D-alanine carboxypeptidase
E2R47_04395	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E2R47_04400	COG1534	Rna-binding protein
E2R47_04410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E2R47_04415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
E2R47_04425	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E2R47_04495	COG0513	Belongs to the DEAD box helicase family
E2R47_04500	COG0814	amino acid
E2R47_04505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E2R47_04525	COG3153	acetyltransferase
E2R47_04540	COG0693	protein deglycase activity
E2R47_04545	COG0702	epimerase
E2R47_04550	COG2823	Periplasmic or secreted lipoprotein
E2R47_04565	COG3107	peptidoglycan biosynthetic process
E2R47_04570	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E2R47_04580	COG1063	alcohol dehydrogenase
E2R47_04585	COG3775	system Galactitol-specific IIC component
E2R47_04590	COG3414	Phosphotransferase system galactitol-specific IIB component
E2R47_04595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E2R47_04610	COG2721	sulfolactate sulfo-lyase activity
E2R47_04620	COG2084	Dehydrogenase
E2R47_04625	COG1929	Belongs to the glycerate kinase type-1 family
E2R47_04670	COG0583	DNA-binding transcription factor activity
E2R47_04690	COG1882	Formate acetyltransferase
E2R47_04695	COG1760	l-serine dehydratase
E2R47_04700	COG0814	amino acid
E2R47_04715	COG1741	Belongs to the pirin family
E2R47_04720	COG0583	DNA-binding transcription factor activity
E2R47_04725	COG3152	Membrane
E2R47_04730	COG0435	Glutathione S-transferase
E2R47_04735	COG2259	Doxx family
E2R47_04745	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
E2R47_04750	COG4575	ribosome binding
E2R47_04755	COG1422	Protein of unknown function (DUF1090)
E2R47_04765	COG0586	Pfam SNARE associated Golgi protein
E2R47_04780	COG0673	inositol 2-dehydrogenase activity
E2R47_04785	COG2949	membrane
E2R47_04790	COG1451	nucleotide metabolic process
E2R47_04800	COG1902	pentaerythritol trinitrate reductase activity
E2R47_04800	COG0446	pyridine nucleotide-disulphide oxidoreductase
E2R47_04810	COG0840	transmembrane signaling receptor activity
E2R47_04815	COG0840	transmembrane signaling receptor activity
E2R47_04820	COG1695	Transcriptional regulator
E2R47_04825	COG2375	cellular response to nickel ion
E2R47_04840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E2R47_04870	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
E2R47_04885	COG4991	sh3 domain protein
E2R47_04890	COG3025	triphosphatase activity
E2R47_04910	COG2268	Band 7 protein
E2R47_04915	COG1585	Membrane protein implicated in regulation of membrane protease activity
E2R47_04955	COG3384	dioxygenase
E2R47_04960	COG0754	glutathionylspermidine amidase activity
E2R47_04975	COG0494	nUDIX hydrolase
E2R47_04980	COG3151	Protein conserved in bacteria
E2R47_04985	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
E2R47_04990	COG3150	esterase
E2R47_04995	COG0187	DNA topoisomerase II activity
E2R47_05000	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
E2R47_05005	COG2249	NAD(P)H dehydrogenase (quinone) activity
E2R47_05010	COG0642	Histidine kinase
E2R47_05015	COG0745	RESPONSE REGULATOR receiver
E2R47_05020	COG3111	PFAM Bacterial OB fold (BOF) protein
E2R47_05025	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E2R47_05035	COG0204	Acyl-transferase
E2R47_05040	COG2132	Multicopper oxidase
E2R47_05080	COG0471	metal ion transport
E2R47_05090	COG1979	alcohol dehydrogenase
E2R47_05095	COG2207	Transcriptional regulator
E2R47_05100	COG0586	Pfam SNARE associated Golgi protein
E2R47_05110	COG0811	peptide transport
E2R47_05115	COG0848	biopolymer transport protein
E2R47_05120	COG1028	Short-chain dehydrogenase reductase Sdr
E2R47_05145	COG0840	transmembrane signaling receptor activity
E2R47_05155	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E2R47_05160	COG0437	4 iron, 4 sulfur cluster binding
E2R47_05165	COG5557	Pfam Polysulphide reductase, NrfD
E2R47_05170	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
E2R47_05175	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E2R47_05180	COG1773	rubredoxin
E2R47_05185	COG0375	protein maturation
E2R47_05190	COG0298	carbon dioxide binding
E2R47_05205	COG0625	glutathione transferase activity
E2R47_05210	COG0754	glutathionylspermidine amidase activity
E2R47_05230	COG0246	Mannitol dehydrogenase
E2R47_05240	COG2271	Major facilitator Superfamily
E2R47_05265	COG1012	belongs to the aldehyde dehydrogenase family
E2R47_05270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E2R47_05280	COG0531	amino acid
E2R47_05315	COG2030	dehydratase
E2R47_05320	COG0427	acetyl-CoA hydrolase
E2R47_05350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E2R47_05360	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
E2R47_05375	COG1811	Na channel or pump
E2R47_05380	COG1982	Orn Lys Arg decarboxylase major
E2R47_05385	COG2211	Major facilitator Superfamily
E2R47_05410	COG3171	Protein conserved in bacteria
E2R47_05420	COG0252	asparaginase activity
E2R47_05430	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E2R47_05445	COG0762	integral membrane protein
E2R47_05450	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E2R47_05455	COG2805	Type II/IV secretion system protein
E2R47_05480	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E2R47_05485	COG2356	endonuclease I
E2R47_05495	COG2814	Major facilitator Superfamily
E2R47_05520	COG1166	arginine decarboxylase activity
E2R47_05530	COG2186	Transcriptional regulator
E2R47_05540	COG0246	Mannitol dehydrogenase
E2R47_05545	COG1063	alcohol dehydrogenase
E2R47_05550	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E2R47_05555	COG2731	YhcH YjgK YiaL family protein
E2R47_05570	COG0501	Belongs to the peptidase M48B family
E2R47_05575	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E2R47_05580	COG1122	ATPase activity
E2R47_05585	COG1122	ATPase activity
E2R47_05620	COG0191	fructose-bisphosphate aldolase activity
E2R47_05630	COG1943	Transposase
E2R47_05640	COG0668	transmembrane transport
E2R47_05650	COG2968	Membrane
E2R47_05670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E2R47_05675	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E2R47_05695	COG0006	proline dipeptidase activity
E2R47_05700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E2R47_05705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E2R47_05735	COG2723	6-phospho-beta-galactosidase activity
E2R47_05745	COG1272	protein, Hemolysin III
E2R47_05770	COG0716	FMN binding
E2R47_05775	COG4974	Belongs to the 'phage' integrase family
E2R47_05810	COG4942	peptidase
E2R47_05850	COG3188	usher protein
E2R47_05885	COG0814	amino acid
E2R47_05900	COG0183	Belongs to the thiolase family
E2R47_05915	COG1028	Short-chain dehydrogenase reductase Sdr
E2R47_05920	COG2814	Major facilitator Superfamily
E2R47_05925	COG1794	racemase activity, acting on amino acids and derivatives
E2R47_05930	COG0583	DNA-binding transcription factor activity
E2R47_05935	COG0019	diaminopimelate decarboxylase activity
E2R47_05940	COG1609	Transcriptional regulator
E2R47_05970	COG0667	Aldo Keto reductase
E2R47_05980	COG0861	Integral membrane protein TerC family
E2R47_06015	COG2165	general secretion pathway protein
E2R47_06020	COG4795	General secretion pathway protein
E2R47_06030	COG4967	type IV pilus modification protein PilV
E2R47_06035	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
E2R47_06040	COG1025	Belongs to the peptidase M16 family
E2R47_06045	COG1074	ATP-dependent DNA helicase activity
E2R47_06050	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E2R47_06060	COG0860	N-Acetylmuramoyl-L-alanine amidase
E2R47_06075	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
E2R47_06080	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E2R47_06085	COG2962	Rard protein
E2R47_06090	COG2166	iron-sulfur cluster assembly
E2R47_06095	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E2R47_06105	COG0583	DNA-binding transcription factor activity
E2R47_06110	COG2363	Small membrane protein
E2R47_06120	COG1349	DNA-binding transcription factor activity
E2R47_06140	COG0738	Major facilitator superfamily
E2R47_06145	COG0235	Class ii aldolase
E2R47_06150	COG1454	alcohol dehydrogenase
E2R47_06165	COG1760	l-serine dehydratase
E2R47_06170	COG0814	amino acid
E2R47_06175	COG1611	Belongs to the LOG family
E2R47_06195	COG3098	single-species biofilm formation
E2R47_06205	COG0716	FMN binding
E2R47_06215	COG2271	Major facilitator Superfamily
E2R47_06220	COG4948	Mandelate Racemase Muconate Lactonizing
E2R47_06225	COG4948	Mandelate Racemase Muconate Lactonizing
E2R47_06230	COG1929	Belongs to the glycerate kinase type-1 family
E2R47_06235	COG2205	protein histidine kinase activity
E2R47_06235	COG4999	Histidine kinase
E2R47_06235	COG3850	Histidine kinase
E2R47_06235	COG3437	response regulator, receiver
E2R47_06245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E2R47_06265	COG3539	Fimbrial protein
E2R47_06270	COG3121	Chaperone
E2R47_06275	COG3188	usher protein
E2R47_06280	COG3539	Fimbrial protein
E2R47_06285	COG3956	TIGRFAM MazG family protein
E2R47_06300	COG0602	queuosine metabolic process
E2R47_06305	COG0321	lipoyl(octanoyl) transferase activity
E2R47_06305	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E2R47_06310	COG0720	synthase
E2R47_06345	COG1203	CRISPR-associated helicase, Cas3
E2R47_06360	COG1857	crispr-associated protein
E2R47_06375	COG1518	maintenance of DNA repeat elements
E2R47_06380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E2R47_06385	COG2234	aminopeptidase activity
E2R47_06455	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
E2R47_06460	COG0163	prenyltransferase activity
E2R47_06470	COG1349	DNA-binding transcription factor activity
E2R47_06475	COG2084	Dehydrogenase
E2R47_06485	COG0235	Class ii aldolase
E2R47_06490	COG3622	Belongs to the hyi family
E2R47_06495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E2R47_06500	COG2610	gluconate transmembrane transporter activity
E2R47_06510	COG0477	Major facilitator Superfamily
E2R47_06585	COG2207	Transcriptional regulator
E2R47_06600	COG4789	Type iii secretion
E2R47_06610	COG1157	protein secretion by the type III secretion system
E2R47_06675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E2R47_06760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E2R47_06765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E2R47_06790	COG0309	Hydrogenase expression formation protein (HypE)
E2R47_06795	COG0409	Hydrogenase expression formation protein
E2R47_06800	COG0298	carbon dioxide binding
E2R47_06805	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
E2R47_06810	COG0375	protein maturation
E2R47_06825	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E2R47_06830	COG0651	ATP synthesis coupled electron transport
E2R47_06835	COG0650	Formate hydrogenlyase subunit 4
E2R47_06840	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
E2R47_06840	COG3261	NADH dehydrogenase
E2R47_06845	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E2R47_06850	COG3260	NADH ubiquinone oxidoreductase 20
E2R47_06860	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E2R47_06870	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E2R47_06875	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
E2R47_06895	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
E2R47_06895	COG0517	IMP dehydrogenase activity
E2R47_06900	COG1349	DNA-binding transcription factor activity
E2R47_06905	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
E2R47_06910	COG1028	Short-chain dehydrogenase reductase Sdr
E2R47_06920	COG3732	PTS system glucitol sorbitol-specific
E2R47_06925	COG3730	PTS system glucitol sorbitol-specific
E2R47_06930	COG2951	lytic endotransglycosylase activity
E2R47_06940	COG1546	Belongs to the CinA family
E2R47_06995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E2R47_07000	COG1238	metal cluster binding
E2R47_07020	COG2814	Major facilitator Superfamily
E2R47_07025	COG1566	PFAM secretion protein HlyD family protein
E2R47_07030	COG1846	Transcriptional regulator
E2R47_07035	COG2814	Major facilitator Superfamily
E2R47_07085	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E2R47_07095	COG4575	ribosome binding
E2R47_07115	COG2916	Histone family protein nucleoid-structuring protein H-NS
E2R47_07125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E2R47_07130	COG0640	Transcriptional regulator
E2R47_07135	COG0401	homolog of Blt101
E2R47_07145	COG1652	LysM domain
E2R47_07150	COG1802	Transcriptional regulator
E2R47_07155	COG1113	amino acid transport
E2R47_07160	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E2R47_07165	COG1012	belongs to the aldehyde dehydrogenase family
E2R47_07170	COG0579	oxidoreductase
E2R47_07200	COG0642	Histidine kinase
E2R47_07205	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
E2R47_07220	COG2990	Protein conserved in bacteria
E2R47_07225	COG1357	PFAM Pentapeptide repeats (8 copies)
E2R47_07245	COG2819	hydrolase of the alpha beta superfamily
E2R47_07300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E2R47_07325	COG2867	negative regulation of translational initiation
E2R47_07340	COG0497	DNA recombination
E2R47_07365	COG4536	flavin adenine dinucleotide binding
E2R47_07370	COG4137	Cytochrome C assembly protein
E2R47_07380	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E2R47_07405	COG2199	diguanylate cyclase activity
E2R47_07415	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E2R47_07420	COG1605	Chorismate mutase
E2R47_07420	COG0287	Prephenate dehydrogenase
E2R47_07430	COG1605	Chorismate mutase
E2R47_07430	COG0077	Prephenate dehydratase
E2R47_07440	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E2R47_07450	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E2R47_07455	COG0564	pseudouridine synthase activity
E2R47_07465	COG0542	response to heat
E2R47_07500	COG0477	Major facilitator Superfamily
E2R47_07505	COG5544	Lipoprotein
E2R47_07510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E2R47_07525	COG3118	belongs to the thioredoxin family
E2R47_07530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E2R47_07550	COG0583	DNA-binding transcription factor activity
E2R47_07555	COG0513	Belongs to the DEAD box helicase family
E2R47_07565	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
E2R47_07595	COG3086	response to oxidative stress
E2R47_07610	COG0681	Belongs to the peptidase S26 family
E2R47_07640	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E2R47_07645	COG0583	DNA-binding transcription factor activity
E2R47_07655	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E2R47_07660	COG1737	Transcriptional regulator
E2R47_07670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E2R47_07670	COG1263	PTS System
E2R47_07675	COG0560	Phosphoserine phosphatase
E2R47_07680	COG0590	tRNA wobble adenosine to inosine editing
E2R47_07700	COG2205	protein histidine kinase activity
E2R47_07705	COG3170	Tfp pilus assembly protein FimV
E2R47_07710	COG2204	response regulator
E2R47_07715	COG0347	Belongs to the P(II) protein family
E2R47_07720	COG3104	oligopeptide transport
E2R47_07725	COG1982	Orn Lys Arg decarboxylase major
E2R47_07730	COG0531	amino acid
E2R47_07735	COG3710	Transcriptional regulator
E2R47_07745	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
E2R47_07750	COG2814	Major facilitator Superfamily
E2R47_07755	COG3711	transcriptional antiterminator
E2R47_07765	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
E2R47_07770	COG2221	Nitrite and sulphite reductase 4Fe-4S
E2R47_07810	COG0822	iron-sulfur transferase activity
E2R47_07830	COG0633	Ferredoxin
E2R47_07835	COG2975	iron-sulfur cluster assembly
E2R47_07860	COG2897	thiosulfate sulfurtransferase activity
E2R47_07865	COG2373	Large extracellular alpha-helical protein
E2R47_07870	COG4953	penicillin-binding protein 1C
E2R47_07875	COG0243	molybdopterin cofactor binding
E2R47_07880	COG0437	4 iron, 4 sulfur cluster binding
E2R47_07920	COG2976	Protein conserved in bacteria
E2R47_07935	COG1645	bacterial-type flagellum-dependent swarming motility
E2R47_07970	COG0517	IMP dehydrogenase activity
E2R47_07970	COG0516	GMP reductase activity
E2R47_08010	COG2200	EAL domain
E2R47_08015	COG0248	Ppx GppA phosphatase
E2R47_08025	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
E2R47_08045	COG2233	PERMEase
E2R47_08055	COG1393	Belongs to the ArsC family
E2R47_08060	COG4783	chaperone-mediated protein folding
E2R47_08065	COG0628	permease
E2R47_08070	COG3835	regulator
E2R47_08075	COG2610	gluconate transmembrane transporter activity
E2R47_08080	COG1929	Belongs to the glycerate kinase type-1 family
E2R47_08085	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E2R47_08090	COG2716	regulation of RNA biosynthetic process
E2R47_08100	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
E2R47_08110	COG2321	neutral zinc metallopeptidase
E2R47_08130	COG1393	Belongs to the ArsC family
E2R47_08140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E2R47_08145	COG3850	Histidine kinase
E2R47_08150	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E2R47_08150	COG0493	'glutamate synthase
E2R47_08165	COG5342	invasion associated locus B
E2R47_08175	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E2R47_08195	COG4917	ethanolamine utilization protein
E2R47_08230	COG4820	ethanolamine utilization protein (EutJ)
E2R47_08260	COG4816	utilization protein
E2R47_08310	COG2837	iron assimilation
E2R47_08315	COG1028	Short-chain dehydrogenase reductase Sdr
E2R47_08330	COG4208	sulfate ABC transporter
E2R47_08375	COG2190	(PTS) system
E2R47_08385	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E2R47_08390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E2R47_08410	COG3530	Putative quorum-sensing-regulated virulence factor
E2R47_08415	COG0385	Bile acid
E2R47_08420	COG0583	DNA-binding transcription factor activity
E2R47_08430	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
E2R47_08435	COG2211	Major facilitator Superfamily
E2R47_08445	COG0583	DNA-binding transcription factor activity
E2R47_08475	COG3415	Transposase
E2R47_08480	COG3415	Transposase
E2R47_08495	COG2200	EAL domain
E2R47_08495	COG2199	diguanylate cyclase activity
E2R47_08500	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E2R47_08515	COG0667	Aldo Keto reductase
E2R47_08525	COG3961	Belongs to the TPP enzyme family
E2R47_08540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E2R47_08545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E2R47_08550	COG0006	proline dipeptidase activity
E2R47_08555	COG1363	Peptidase, m42
E2R47_08565	COG2207	Transcriptional regulator
E2R47_08570	COG0436	Aminotransferase
E2R47_08580	COG1560	Kdo2-lipid A biosynthetic process
E2R47_08600	COG1840	ABC-type Fe3 transport system, periplasmic component
E2R47_08625	COG2116	formate transmembrane transporter activity
E2R47_08640	COG3691	Protein conserved in bacteria
E2R47_08655	COG2062	phosphohistidine phosphatase, SixA
E2R47_08665	COG2890	protein-(glutamine-N5) methyltransferase activity
E2R47_08680	COG0730	response to heat
E2R47_08685	COG3101	peptidyl-lysine hydroxylation
E2R47_08700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E2R47_08720	COG3423	Transcriptional regulator
E2R47_08745	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E2R47_08755	COG0586	Pfam SNARE associated Golgi protein
E2R47_08765	COG0285	dihydrofolate synthase activity
E2R47_08770	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
E2R47_08775	COG1286	toxin biosynthetic process
E2R47_08780	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
E2R47_08785	COG3829	transcription factor binding
E2R47_08795	COG0531	amino acid
E2R47_08800	COG3457	Alanine racemase
E2R47_08805	COG0833	amino acid
E2R47_08810	COG0163	prenyltransferase activity
E2R47_08830	COG4215	(ABC) transporter
E2R47_08835	COG4160	amino acid transport
E2R47_08845	COG1090	epimerase
E2R47_08850	COG0625	glutathione transferase activity
E2R47_08855	COG0625	glutathione transferase activity
E2R47_08860	COG0622	Phosphoesterase
E2R47_08865	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
E2R47_08870	COG1609	Transcriptional regulator
E2R47_08880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E2R47_08890	COG3037	sugar-specific permease SgaT UlaA
E2R47_08895	COG3959	Transketolase, thiamine diphosphate binding domain
E2R47_08900	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
E2R47_08905	COG1288	antiporter activity
E2R47_08915	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
E2R47_08935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E2R47_08940	COG0471	metal ion transport
E2R47_08940	COG0490	domain, Protein
E2R47_08955	COG0436	Aminotransferase
E2R47_08965	COG0583	DNA-binding transcription factor activity
E2R47_08990	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
E2R47_09000	COG1034	ATP synthesis coupled electron transport
E2R47_09015	COG0839	Belongs to the complex I subunit 6 family
E2R47_09025	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E2R47_09030	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E2R47_09045	COG2304	oxidoreductase activity
E2R47_09050	COG0784	Response regulator, receiver
E2R47_09050	COG0835	chemotaxis
E2R47_09060	COG2153	protein acetylation
E2R47_09065	COG4575	ribosome binding
E2R47_09070	COG1169	isochorismate synthase
E2R47_09160	COG5160	protein modification by small protein removal
E2R47_09170	COG0247	lactate metabolic process
E2R47_09180	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E2R47_09185	COG2271	Major facilitator Superfamily
E2R47_09190	COG0584	glycerophosphoryl diester phosphodiesterase
E2R47_09195	COG0583	DNA-binding transcription factor activity
E2R47_09200	COG2814	Major facilitator Superfamily
E2R47_09205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E2R47_09235	COG4948	Mandelate Racemase Muconate Lactonizing
E2R47_09245	COG2205	protein histidine kinase activity
E2R47_09245	COG0784	Response regulator, receiver
E2R47_09255	COG2198	Histidine kinase
E2R47_09255	COG0642	Histidine kinase
E2R47_09260	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E2R47_09280	COG4615	Cyclic peptide transporter
E2R47_09290	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E2R47_09290	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
E2R47_09295	COG3062	negative regulation of establishment of protein localization
E2R47_09305	COG0437	4 iron, 4 sulfur cluster binding
E2R47_09310	COG0348	domain, Protein
E2R47_09315	COG3043	anaerobic respiration
E2R47_09320	COG3005	denitrification pathway
E2R47_09330	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E2R47_09335	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E2R47_09340	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E2R47_09350	COG1138	Cytochrome C-type biogenesis protein
E2R47_09360	COG3088	subunit of a heme lyase
E2R47_09360	COG4235	cytochrome complex assembly
E2R47_09365	COG2197	response regulator
E2R47_09420	COG1061	Type III restriction enzyme res subunit
E2R47_09425	COG1187	pseudouridine synthase activity
E2R47_09430	COG2814	Major facilitator Superfamily
E2R47_09440	COG4172	Belongs to the ABC transporter superfamily
E2R47_09445	COG4239	(ABC) transporter, permease
E2R47_09450	COG4174	ABC transporter (Permease)
E2R47_09455	COG4166	transmembrane transport
E2R47_09460	COG2200	EAL domain
E2R47_09465	COG0791	NLP P60 protein
E2R47_09470	COG0671	phosphoesterase, PA-phosphatase related
E2R47_09475	COG0523	cobalamin synthesis protein
E2R47_09510	COG1105	Belongs to the carbohydrate kinase PfkB family
E2R47_09515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E2R47_09515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E2R47_09515	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
E2R47_09525	COG2855	membrane
E2R47_09530	COG0583	DNA-binding transcription factor activity
E2R47_09535	COG0833	amino acid
E2R47_09545	COG4771	TonB-dependent receptor
E2R47_09550	COG2271	Major facilitator Superfamily
E2R47_09555	COG0560	Phosphoserine phosphatase
E2R47_09560	COG1760	l-serine dehydratase
E2R47_09580	COG2311	Membrane
E2R47_09610	COG0493	'glutamate synthase
E2R47_09620	COG2949	membrane
E2R47_09630	COG1346	cytolysis
E2R47_09645	COG2271	Major facilitator Superfamily
E2R47_09660	COG0625	glutathione transferase activity
E2R47_09665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E2R47_09680	COG1538	Outer membrane efflux protein
E2R47_09685	COG1028	Short-chain dehydrogenase reductase Sdr
E2R47_09690	COG0586	Pfam SNARE associated Golgi protein
E2R47_09700	COG1686	Belongs to the peptidase S11 family
E2R47_09705	COG0277	FAD linked oxidase domain protein
E2R47_09715	COG1732	Glycine betaine
E2R47_09720	COG1174	glycine betaine transport
E2R47_09725	COG1125	glycine betaine transport
E2R47_09730	COG1174	glycine betaine transport
E2R47_09745	COG3275	phosphorelay sensor kinase activity
E2R47_09755	COG4807	Protein conserved in bacteria
E2R47_09765	COG4808	Protein conserved in bacteria
E2R47_09790	COG3121	Chaperone
E2R47_09800	COG3539	Fimbrial protein
E2R47_09805	COG5455	response to cobalt ion
E2R47_09820	COG2188	Transcriptional regulator
E2R47_09825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E2R47_09830	COG1397	ADP-ribosylglycohydrolase
E2R47_09835	COG2211	Major facilitator Superfamily
E2R47_09840	COG1830	Aldolase
E2R47_09890	COG0745	RESPONSE REGULATOR receiver
E2R47_09895	COG2205	protein histidine kinase activity
E2R47_09925	COG0443	Heat shock 70 kDa protein
E2R47_09930	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
E2R47_09935	COG3447	MASE1 domain protein
E2R47_09935	COG5001	Diguanylate cyclase
E2R47_09935	COG5002	protein histidine kinase activity
E2R47_09950	COG2982	Protein involved in outer membrane biogenesis
E2R47_09955	COG1253	flavin adenine dinucleotide binding
E2R47_09975	COG0463	Glycosyl transferase, family 2
E2R47_09980	COG1045	serine acetyltransferase
E2R47_09985	COG0438	transferase activity, transferring glycosyl groups
E2R47_09995	COG1216	Glycosyl transferase, family 2
E2R47_10000	COG0110	maltose O-acetyltransferase activity
E2R47_10005	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
E2R47_10010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E2R47_10020	COG0297	glycogen (starch) synthase activity
E2R47_10035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E2R47_10040	COG2244	polysaccharide biosynthetic process
E2R47_10045	COG2327	Polysaccharide pyruvyl transferase
E2R47_10060	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E2R47_10090	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
E2R47_10115	COG0463	Glycosyl transferase, family 2
E2R47_10140	COG0438	transferase activity, transferring glycosyl groups
E2R47_10225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E2R47_10230	COG0583	DNA-binding transcription factor activity
E2R47_10240	COG0531	amino acid
E2R47_10245	COG2925	Exonuclease
E2R47_10265	COG0437	4 iron, 4 sulfur cluster binding
E2R47_10280	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E2R47_10285	COG1289	transmembrane transporter activity
E2R47_10310	COG4810	utilization protein
E2R47_10320	COG4656	Part of a membrane complex involved in electron transport
E2R47_10325	COG1454	alcohol dehydrogenase
E2R47_10325	COG1012	belongs to the aldehyde dehydrogenase family
E2R47_10355	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
E2R47_10360	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
E2R47_10395	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
E2R47_10430	COG2241	protein methyltransferase activity
E2R47_10440	COG2875	Belongs to the precorrin methyltransferase family
E2R47_10485	COG1122	ATPase activity
E2R47_10520	COG0534	Mate efflux family protein
E2R47_10565	COG3209	COG3209 Rhs family protein
E2R47_10575	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
E2R47_10585	COG2249	NAD(P)H dehydrogenase (quinone) activity
E2R47_10590	COG1733	regulation of RNA biosynthetic process
E2R47_10605	COG0582	viral genome integration into host DNA
E2R47_10655	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E2R47_10665	COG1418	mRNA catabolic process
E2R47_10670	COG0270	DNA (cytosine-5-)-methyltransferase activity
E2R47_10675	COG3727	T/G mismatch-specific endonuclease activity
E2R47_10680	COG0697	spore germination
E2R47_10685	COG2354	Protein conserved in bacteria
E2R47_10690	COG5475	Uncharacterized small protein (DUF2158)
E2R47_10725	COG1987	bacterial-type flagellum assembly
E2R47_10735	COG3190	flagellar
E2R47_10760	COG2882	bacterial-type flagellum organization
E2R47_10775	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E2R47_10795	COG0425	Belongs to the sulfur carrier protein TusA family
E2R47_10840	COG1191	sigma factor activity
E2R47_10870	COG2197	response regulator
E2R47_10885	COG2197	response regulator
E2R47_10930	COG3012	SEC-C Motif Domain Protein
E2R47_10930	COG3318	Belongs to the UPF0149 family
E2R47_10935	COG0814	amino acid
E2R47_10945	COG1528	Iron-storage protein
E2R47_10960	COG1528	Iron-storage protein
E2R47_11040	COG0745	RESPONSE REGULATOR receiver
E2R47_11065	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
E2R47_11080	COG3102	Protein conserved in bacteria
E2R47_11100	COG3788	relative of glutathione S-transferase, MAPEG superfamily
E2R47_11105	COG1801	Protein of unknown function DUF72
E2R47_11110	COG1335	isochorismatase
E2R47_11120	COG0494	nUDIX hydrolase
E2R47_11155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E2R47_11165	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
E2R47_11170	COG0739	heme binding
E2R47_11175	COG1560	Kdo2-lipid A biosynthetic process
E2R47_11185	COG1737	Transcriptional regulator
E2R47_11195	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E2R47_11200	COG0129	dihydroxy-acid dehydratase activity
E2R47_11205	COG0800	Aldolase
E2R47_11215	COG3141	response to X-ray
E2R47_11225	COG2979	Protein of unknown function (DUF533)
E2R47_11230	COG1770	oligopeptidase
E2R47_11235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E2R47_11240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E2R47_11250	COG2372	response to copper ion
E2R47_11255	COG1276	copper resistance
E2R47_11265	COG0582	viral genome integration into host DNA
E2R47_11340	COG5001	Diguanylate cyclase
E2R47_11340	COG4251	negative regulation of phosphorylation
E2R47_11340	COG3706	GGDEF domain
E2R47_11340	COG2203	Gaf domain
E2R47_11345	COG2015	COG2015, Alkyl sulfatase and related hydrolases
E2R47_11390	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
E2R47_11455	COG5562	phage envelope protein
E2R47_11490	COG3008	intermembrane lipid transfer
E2R47_11495	COG2995	paraquat-inducible protein a
E2R47_11500	COG1956	GAF domain-containing protein
E2R47_11520	COG2814	Major facilitator Superfamily
E2R47_11525	COG1414	Transcriptional regulator
E2R47_11550	COG1278	Cold shock
E2R47_11555	COG0768	penicillin binding
E2R47_11560	COG2226	methyltransferase
E2R47_11575	COG3716	PTS system mannose fructose sorbose family IID component
E2R47_11580	COG3715	PTS system
E2R47_11585	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E2R47_11585	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E2R47_11590	COG1253	flavin adenine dinucleotide binding
E2R47_11595	COG2200	EAL domain
E2R47_11600	COG1760	l-serine dehydratase
E2R47_11620	COG0251	oxidation-reduction process
E2R47_11625	COG1199	ATP-dependent helicase activity
E2R47_11635	COG3065	identical protein binding
E2R47_11640	COG0318	PFAM AMP-dependent synthetase and ligase
E2R47_11645	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
E2R47_11655	COG2894	cell division
E2R47_11670	COG0179	Fumarylacetoacetate (FAA) hydrolase
E2R47_11710	COG2719	SpoVR family
E2R47_11730	COG1619	proteins homologs of microcin C7 resistance protein MccF
E2R47_11755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
E2R47_11765	COG1294	oxidase, subunit
E2R47_11770	COG1271	oxidase subunit
E2R47_11775	COG1773	rubredoxin
E2R47_11780	COG1999	signal sequence binding
E2R47_11785	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E2R47_11790	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
E2R47_11800	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E2R47_11820	COG0012	GTP binding
E2R47_11835	COG0659	secondary active sulfate transmembrane transporter activity
E2R47_11840	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
E2R47_11870	COG3094	Invasion gene expression up-regulator, SirB
E2R47_11875	COG2912	Transglutaminase-like superfamily
E2R47_11885	COG0387	Pfam Sodium calcium exchanger
E2R47_11890	COG4572	Cation transport regulator
E2R47_11895	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
E2R47_11900	COG4932	domain protein
E2R47_11905	COG2197	response regulator
E2R47_11910	COG3850	Histidine kinase
E2R47_11920	COG2223	nitrite transmembrane transporter activity
E2R47_11925	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E2R47_11930	COG1140	nitrate reductase beta subunit
E2R47_11935	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E2R47_11940	COG2181	nitrate reductase activity
E2R47_11980	COG0788	formyltetrahydrofolate deformylase activity
E2R47_11990	COG1752	Esterase of the alpha-beta hydrolase superfamily
E2R47_11995	COG0745	RESPONSE REGULATOR receiver
E2R47_12000	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E2R47_12015	COG1454	alcohol dehydrogenase
E2R47_12015	COG1012	belongs to the aldehyde dehydrogenase family
E2R47_12020	COG2095	MarC family integral membrane protein
E2R47_12055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E2R47_12075	COG2350	Protein conserved in bacteria
E2R47_12085	COG1607	acyl-coa hydrolase
E2R47_12105	COG3047	cAMP biosynthetic process
E2R47_12110	COG3546	catalase activity
E2R47_12115	COG3685	Protein conserved in bacteria
E2R47_12120	COG3685	Protein conserved in bacteria
E2R47_12125	COG3729	General stress protein
E2R47_12140	COG0134	indole-3-glycerol-phosphate synthase activity
E2R47_12140	COG0135	phosphoribosylanthranilate isomerase activity
E2R47_12165	COG0009	L-threonylcarbamoyladenylate synthase
E2R47_12180	COG1028	Short-chain dehydrogenase reductase Sdr
E2R47_12185	COG0616	signal peptide processing
E2R47_12195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E2R47_12230	COG0671	phosphoesterase, PA-phosphatase related
E2R47_12235	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
E2R47_12240	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
E2R47_12250	COG0023	Translation Initiation Factor
E2R47_12260	COG1349	DNA-binding transcription factor activity
E2R47_12270	COG5001	Diguanylate cyclase
E2R47_12280	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E2R47_12280	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E2R47_12320	COG4171	peptide transport system, permease
E2R47_12365	COG4168	peptide transport system, permease
E2R47_12375	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
E2R47_12380	COG1842	Phage shock protein A
E2R47_12390	COG1983	PspC domain protein
E2R47_12400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E2R47_12405	COG3106	COG3106 Predicted ATPase
E2R47_12415	COG3283	Transcriptional regulator of aromatic amino acids metabolism
E2R47_12425	COG4948	Mandelate Racemase Muconate Lactonizing
E2R47_12430	COG2866	Carboxypeptidase
E2R47_12435	COG4166	transmembrane transport
E2R47_12445	COG0583	DNA-binding transcription factor activity
E2R47_12450	COG0656	L-ascorbic acid biosynthetic process
E2R47_12455	COG1028	Short-chain dehydrogenase reductase Sdr
E2R47_12460	COG1309	transcriptional regulator
E2R47_12495	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
E2R47_12515	COG0668	transmembrane transport
E2R47_12520	COG3182	Iron-regulated membrane protein
E2R47_12535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E2R47_12540	COG2840	Smr protein MutS2
E2R47_12550	COG0840	transmembrane signaling receptor activity
E2R47_12565	COG0513	Belongs to the DEAD box helicase family
E2R47_12585	COG2076	Multidrug Resistance protein
E2R47_12590	COG0589	response to stress
E2R47_12595	COG1013	pyruvate-flavodoxin oxidoreductase activity
E2R47_12595	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E2R47_12595	COG0674	pyruvate-flavodoxin oxidoreductase activity
E2R47_12595	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E2R47_12605	COG3042	response to heat
E2R47_12610	COG3187	Heat shock protein
E2R47_12615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E2R47_12620	COG2911	Protein conserved in bacteria
E2R47_12630	COG3784	Protein of unknown function (DUF1318)
E2R47_12645	COG1643	Atp-dependent helicase
E2R47_12650	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E2R47_12655	COG3038	cytochrome b561
E2R47_12660	COG0500	methyltransferase
E2R47_12670	COG0765	amino acid transport
E2R47_12680	COG0765	amino acid transport
E2R47_12685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E2R47_12725	COG0840	transmembrane signaling receptor activity
E2R47_12730	COG0583	DNA-binding transcription factor activity
E2R47_12735	COG5383	Protein conserved in bacteria
E2R47_12740	COG2272	Belongs to the type-B carboxylesterase lipase family
E2R47_12750	COG2353	YceI-like domain
E2R47_12755	COG2186	Transcriptional regulator
E2R47_12760	COG1063	alcohol dehydrogenase
E2R47_12765	COG2271	Major facilitator Superfamily
E2R47_12770	COG1028	Short-chain dehydrogenase reductase Sdr
E2R47_12785	COG1349	DNA-binding transcription factor activity
E2R47_12790	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E2R47_12795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E2R47_12800	COG0434	BtpA family
E2R47_12805	COG3775	system Galactitol-specific IIC component
E2R47_12810	COG3414	Phosphotransferase system galactitol-specific IIB component
E2R47_12820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E2R47_12825	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E2R47_12830	COG1275	C4-dicarboxylate transporter malic acid transport protein
E2R47_12835	COG0500	methyltransferase
E2R47_12845	COG3135	benzoate transporter
E2R47_12850	COG1396	sequence-specific DNA binding
E2R47_12855	COG0826	peptidase U32
E2R47_12880	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
E2R47_12885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E2R47_12925	COG3238	Protein conserved in bacteria
E2R47_12935	COG2130	NADP-dependent
E2R47_12940	COG1802	Transcriptional regulator
E2R47_12945	COG4772	TonB-dependent receptor
E2R47_12950	COG3391	amine dehydrogenase activity
E2R47_12985	COG2181	nitrate reductase activity
E2R47_12990	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E2R47_12995	COG1140	nitrate reductase beta subunit
E2R47_13000	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E2R47_13040	COG0243	molybdopterin cofactor binding
E2R47_13040	COG3383	formate dehydrogenase (NAD+) activity
E2R47_13045	COG0243	molybdopterin cofactor binding
E2R47_13045	COG3383	formate dehydrogenase (NAD+) activity
E2R47_13050	COG0437	4 iron, 4 sulfur cluster binding
E2R47_13055	COG2864	formate dehydrogenase
E2R47_13060	COG1064	alcohol dehydrogenase
E2R47_13080	COG1764	response to oxidative stress
E2R47_13110	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
E2R47_13125	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
E2R47_13130	COG1757	Na H antiporter
E2R47_13135	COG1609	Transcriptional regulator
E2R47_13190	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
E2R47_13200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E2R47_13215	COG2271	Major facilitator Superfamily
E2R47_13220	COG1063	alcohol dehydrogenase
E2R47_13225	COG2186	Transcriptional regulator
E2R47_13235	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E2R47_13240	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
E2R47_13265	COG1773	rubredoxin
E2R47_13290	COG3781	membrane
E2R47_13305	COG1012	belongs to the aldehyde dehydrogenase family
E2R47_13310	COG0583	DNA-binding transcription factor activity
E2R47_13325	COG1846	Transcriptional regulator
E2R47_13345	COG2814	Major facilitator Superfamily
E2R47_13355	COG3111	PFAM Bacterial OB fold (BOF) protein
E2R47_13360	COG1546	Belongs to the CinA family
E2R47_13365	COG3729	General stress protein
E2R47_13380	COG4221	oxidoreductase activity
E2R47_13385	COG1802	Transcriptional regulator
E2R47_13395	COG0246	Mannitol dehydrogenase
E2R47_13400	COG0477	Major facilitator Superfamily
E2R47_13405	COG1063	alcohol dehydrogenase
E2R47_13425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E2R47_13440	COG0243	molybdopterin cofactor binding
E2R47_13445	COG0243	molybdopterin cofactor binding
E2R47_13450	COG0437	4 iron, 4 sulfur cluster binding
E2R47_13455	COG3302	dmso reductase anchor subunit
E2R47_13460	COG3381	protein complex oligomerization
E2R47_13470	COG0243	molybdopterin cofactor binding
E2R47_13475	COG0437	4 iron, 4 sulfur cluster binding
E2R47_13480	COG3302	dmso reductase anchor subunit
E2R47_13515	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
E2R47_13520	COG1940	carbohydrate kinase activity
E2R47_13525	COG0583	DNA-binding transcription factor activity
E2R47_13530	COG2814	Major facilitator Superfamily
E2R47_13540	COG3591	Belongs to the peptidase S1B family
E2R47_13560	COG0628	permease
E2R47_13565	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
E2R47_13570	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
E2R47_13580	COG0531	amino acid
E2R47_13585	COG3136	membrane protein required for alginate biosynthesis
E2R47_13590	COG0745	RESPONSE REGULATOR receiver
E2R47_13600	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E2R47_13605	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
E2R47_13610	COG2205	protein histidine kinase activity
E2R47_13635	COG5339	Protein conserved in bacteria
E2R47_13640	COG1609	Transcriptional regulator
E2R47_13645	COG1263	PTS System
E2R47_13645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E2R47_13650	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
E2R47_13655	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
E2R47_13660	COG0673	inositol 2-dehydrogenase activity
E2R47_13710	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E2R47_13720	COG0625	glutathione transferase activity
E2R47_13740	COG3895	Periplasmic Protein
E2R47_13750	COG3133	Outer membrane lipoprotein
E2R47_13765	COG1566	PFAM secretion protein HlyD family protein
E2R47_13780	COG4989	oxidoreductase activity
E2R47_13785	COG3313	Fe-S protein
E2R47_13790	COG1309	transcriptional regulator
E2R47_13795	COG1902	pentaerythritol trinitrate reductase activity
E2R47_13800	COG0346	lactoylglutathione lyase activity
E2R47_13815	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
E2R47_13820	COG0791	NLP P60 protein
E2R47_13825	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
E2R47_13840	COG0583	DNA-binding transcription factor activity
E2R47_13845	COG2814	Major facilitator Superfamily
E2R47_13850	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E2R47_13855	COG0307	riboflavin synthase, alpha
E2R47_14025	COG2205	protein histidine kinase activity
E2R47_14025	COG3437	response regulator, receiver
E2R47_14025	COG3850	Histidine kinase
E2R47_14025	COG4999	Histidine kinase
E2R47_14035	COG0789	Transcriptional regulator
E2R47_14040	COG3272	Protein of unknown function (DUF1722)
E2R47_14075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E2R47_14085	COG2267	carboxylic ester hydrolase activity
E2R47_14090	COG0531	amino acid
E2R47_14105	COG4238	major outer membrane lipoprotein
E2R47_14110	COG1376	ErfK ybiS ycfS ynhG family protein
E2R47_14125	COG0719	Fe-S assembly protein
E2R47_14130	COG0396	ATPase activity
E2R47_14135	COG0719	Fe-S assembly protein
E2R47_14140	COG0316	Belongs to the HesB IscA family
E2R47_14155	COG2050	protein possibly involved in aromatic compounds catabolism
E2R47_14160	COG0247	lactate metabolic process
E2R47_14160	COG0277	FAD linked oxidase domain protein
E2R47_14165	COG0628	permease
E2R47_14180	COG0738	Major facilitator superfamily
E2R47_14185	COG2271	Major facilitator Superfamily
E2R47_14200	COG4670	ketone body catabolic process
E2R47_14205	COG1960	acyl-CoA dehydrogenase activity
E2R47_14210	COG1917	Cupin 2, conserved barrel domain protein
E2R47_14210	COG2207	Transcriptional regulator
E2R47_14215	COG2086	electron transfer activity
E2R47_14220	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
E2R47_14225	COG0644	oxidoreductase
E2R47_14230	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
E2R47_14235	COG0318	PFAM AMP-dependent synthetase and ligase
E2R47_14240	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E2R47_14240	COG0574	Belongs to the PEP-utilizing enzyme family
E2R47_14270	COG4256	Hemin uptake protein
E2R47_14285	COG0791	NLP P60 protein
E2R47_14295	COG0386	Belongs to the glutathione peroxidase family
E2R47_14360	COG3137	Salt-induced outer membrane protein
E2R47_14365	COG1105	Belongs to the carbohydrate kinase PfkB family
E2R47_14385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E2R47_14390	COG1988	membrane-bound metal-dependent
E2R47_14405	COG0753	catalase activity
E2R47_14415	COG1486	melibiose metabolic process
E2R47_14420	COG1917	Cupin 2, conserved barrel domain protein
E2R47_14420	COG2169	Transcriptional regulator
E2R47_14425	COG1447	Phosphotransferase system cellobiose-specific component IIA
E2R47_14430	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E2R47_14435	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E2R47_14445	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E2R47_14455	COG0322	excinuclease ABC activity
E2R47_14460	COG3678	ATP-independent chaperone mediated protein folding
E2R47_14470	COG2988	succinylglutamate desuccinylase activity
E2R47_14475	COG3724	N-succinylarginine dihydrolase activity
E2R47_14495	COG0708	Exodeoxyribonuclease III
E2R47_14500	COG0494	nUDIX hydrolase
E2R47_14525	COG0778	Nitroreductase
E2R47_14530	COG0616	signal peptide processing
E2R47_14535	COG0252	asparaginase activity
E2R47_14540	COG1335	isochorismatase
E2R47_14545	COG3139	Protein of unknown function (DUF1315)
E2R47_14555	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
E2R47_14570	COG0656	L-ascorbic acid biosynthetic process
E2R47_14575	COG0641	radical SAM
E2R47_14580	COG3713	MltA-interacting MipA family protein
E2R47_14585	COG2766	serine protein kinase
E2R47_14600	COG2199	diguanylate cyclase activity
E2R47_14605	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E2R47_14620	COG2207	Transcriptional regulator
E2R47_14625	COG2807	transmembrane transport
E2R47_14630	COG3189	MarR family transcriptional regulator
E2R47_14640	COG3042	response to heat
E2R47_14650	COG2261	transglycosylase associated protein
E2R47_14670	COG3615	Tellurite resistance protein tehB
E2R47_14685	COG1605	Chorismate mutase
E2R47_14695	COG0789	Transcriptional regulator
E2R47_14710	COG3443	Belongs to the bacterial solute-binding protein 9 family
E2R47_14725	COG0668	transmembrane transport
E2R47_14730	COG1124	(ABC) transporter
E2R47_14760	COG3038	cytochrome b561
E2R47_14770	COG0071	Belongs to the small heat shock protein (HSP20) family
E2R47_14820	COG1278	Cold shock
E2R47_14835	COG3021	interspecies interaction between organisms
E2R47_14870	COG0538	isocitrate dehydrogenase activity
E2R47_14900	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
E2R47_14915	COG2850	peptidyl-arginine hydroxylation
E2R47_14935	COG1176	ABC-type spermidine putrescine transport system, permease component I
E2R47_14945	COG1177	transmembrane transport
E2R47_14950	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E2R47_14955	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
E2R47_14965	COG4591	ABC-type transport system involved in lipoprotein release permease component
E2R47_14975	COG4591	ABC-type transport system involved in lipoprotein release permease component
E2R47_14980	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
E2R47_14985	COG1376	ErfK ybiS ycfS ynhG family protein
E2R47_14985	COG1388	LysM domain
E2R47_14995	COG1309	transcriptional regulator
E2R47_15000	COG3134	Outer membrane lipoprotein
E2R47_15005	COG1252	NADH dehydrogenase
E2R47_15030	COG5633	Lipoprotein
E2R47_15035	COG0537	adenosine 5'-monophosphoramidase activity
E2R47_15040	COG4773	Receptor
E2R47_15050	COG0084	hydrolase, TatD family'
E2R47_15055	COG0470	DNA polymerase III
E2R47_15065	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
E2R47_15070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E2R47_15075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E2R47_15085	COG1028	Short-chain dehydrogenase reductase Sdr
E2R47_15110	COG1399	metal-binding, possibly nucleic acid-binding protein
E2R47_15140	COG1530	ribonuclease E activity
E2R47_15150	COG1943	Transposase
E2R47_15170	COG1256	bacterial-type flagellum assembly
E2R47_15190	COG4786	Flagellar basal body rod
E2R47_15200	COG1749	Flagellar hook protein flgE
E2R47_15205	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
E2R47_15210	COG1558	bacterial-type flagellum-dependent cell motility
E2R47_15235	COG3418	PFAM FlgN family protein
E2R47_15255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E2R47_15265	COG2999	glutathione oxidoreductase activity
E2R47_15300	COG3038	cytochrome b561
E2R47_15315	COG1560	Kdo2-lipid A biosynthetic process
E2R47_15335	COG5645	(Lipo)protein
E2R47_15340	COG2943	transferase activity, transferring hexosyl groups
E2R47_15360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E2R47_15365	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
E2R47_15405	COG1462	curli production assembly transport component CsgG
E2R47_15415	COG3381	protein complex oligomerization
E2R47_15445	COG0673	inositol 2-dehydrogenase activity
E2R47_15450	COG2814	Major facilitator Superfamily
E2R47_15455	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
E2R47_15470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E2R47_15475	COG1737	Transcriptional regulator
E2R47_15480	COG1702	phosphate starvation-inducible protein PhoH
E2R47_15505	COG1309	transcriptional regulator
E2R47_15510	COG3729	General stress protein
E2R47_15530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E2R47_15535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E2R47_15535	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E2R47_15540	COG4232	protein-disulfide reductase activity
E2R47_15595	COG3971	2-oxopent-4-enoate hydratase activity
E2R47_15605	COG3384	dioxygenase
E2R47_15610	COG1012	belongs to the aldehyde dehydrogenase family
E2R47_15620	COG1846	Transcriptional regulator
E2R47_15625	COG2368	4-hydroxyphenylacetate
E2R47_15645	COG0745	RESPONSE REGULATOR receiver
E2R47_15650	COG2205	protein histidine kinase activity
E2R47_15700	COG0670	Belongs to the BI1 family
E2R47_15710	COG1254	Belongs to the acylphosphatase family
E2R47_15720	COG1881	PFAM PEBP family protein
E2R47_15735	COG1832	CoA-binding protein
E2R47_15750	COG0210	DNA helicase
E2R47_15755	COG3304	Inner membrane component domain
E2R47_15760	COG1289	transmembrane transporter activity
E2R47_15765	COG3070	regulator of competence-specific genes
E2R47_15785	COG1067	ATP-dependent peptidase activity
E2R47_15795	COG3130	regulation of translation
E2R47_15800	COG3009	Protein conserved in bacteria
E2R47_15805	COG3008	intermembrane lipid transfer
E2R47_15805	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E2R47_15810	COG2995	paraquat-inducible protein a
E2R47_15815	COG0488	(ABC) transporter
E2R47_15825	COG0633	Ferredoxin
E2R47_15825	COG3217	Mosc domain protein beta barrel domain protein
E2R47_15840	COG0308	aminopeptidase N
E2R47_15850	COG1115	amino acid carrier protein
E2R47_15865	COG1522	sequence-specific DNA binding
E2R47_15875	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E2R47_15885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E2R47_15890	COG3108	Peptidase M15
E2R47_15895	COG2989	Protein conserved in bacteria
E2R47_15910	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
E2R47_15920	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E2R47_15925	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E2R47_15930	COG3173	Aminoglycoside phosphotransferase
E2R47_15945	COG3214	Protein conserved in bacteria
E2R47_15960	COG0658	competence protein
E2R47_15960	COG2333	competence protein COMEC
E2R47_15970	COG0539	negative regulation of cytoplasmic translation
E2R47_15980	COG0501	Belongs to the peptidase M48B family
E2R47_15995	COG2323	membrane
E2R47_16000	COG1944	ATP diphosphatase activity
E2R47_16005	COG2116	formate transmembrane transporter activity
E2R47_16010	COG1882	Formate acetyltransferase
E2R47_16025	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E2R47_16030	COG0531	amino acid
E2R47_16040	COG3302	dmso reductase anchor subunit
E2R47_16045	COG0437	4 iron, 4 sulfur cluster binding
E2R47_16050	COG0243	molybdopterin cofactor binding
E2R47_16060	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E2R47_16080	COG0492	ferredoxin-NADP+ reductase activity
E2R47_16085	COG4988	ABC transporter
E2R47_16090	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E2R47_16110	COG0583	DNA-binding transcription factor activity
E2R47_16120	COG1335	isochorismatase
E2R47_16165	COG0542	response to heat
E2R47_16175	COG1278	Cold shock
E2R47_16180	COG1136	(ABC) transporter
E2R47_16180	COG0577	efflux transmembrane transporter activity
E2R47_16185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E2R47_16190	COG2990	Protein conserved in bacteria
E2R47_16195	COG3593	DNA synthesis involved in DNA repair
E2R47_16200	COG2431	L-lysine efflux transmembrane transporter activity
E2R47_16210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E2R47_16215	COG0028	Belongs to the TPP enzyme family
E2R47_16220	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
E2R47_16225	COG0702	epimerase
E2R47_16230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E2R47_16235	COG3023	N-Acetylmuramoyl-L-alanine amidase
E2R47_16250	COG1126	abc transporter atp-binding protein
E2R47_16255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E2R47_16260	COG4215	(ABC) transporter
E2R47_16265	COG4160	amino acid transport
E2R47_16270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E2R47_16300	COG1177	transmembrane transport
E2R47_16305	COG1176	ABC-type spermidine putrescine transport system, permease component I
E2R47_16310	COG3842	ATPase activity
E2R47_16315	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E2R47_16340	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E2R47_16360	COG3226	Transcriptional regulator
E2R47_16365	COG0738	Major facilitator superfamily
E2R47_16370	COG0561	phosphatase activity
E2R47_16375	COG2814	Major facilitator Superfamily
E2R47_16380	COG0671	phosphoesterase, PA-phosphatase related
E2R47_16385	COG1349	DNA-binding transcription factor activity
E2R47_16390	COG1686	Belongs to the peptidase S11 family
E2R47_16395	COG0625	glutathione transferase activity
E2R47_16400	COG2133	pyrroloquinoline quinone binding
E2R47_16425	COG0747	negative chemotaxis
E2R47_16450	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E2R47_16460	COG0561	phosphatase activity
E2R47_16470	COG0488	(ABC) transporter
E2R47_16475	COG1376	ErfK ybiS ycfS ynhG family protein
E2R47_16480	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E2R47_16485	COG1321	iron dependent repressor
E2R47_16495	COG2194	sulfuric ester hydrolase activity
E2R47_16500	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
E2R47_16515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E2R47_16520	COG0765	amino acid transport
E2R47_16525	COG1126	abc transporter atp-binding protein
E2R47_16530	COG0668	transmembrane transport
E2R47_16540	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E2R47_16550	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E2R47_16560	COG0513	Belongs to the DEAD box helicase family
E2R47_16565	COG1309	transcriptional regulator
E2R47_16575	COG1131	(ABC) transporter
E2R47_16580	COG0842	Transport permease protein
E2R47_16585	COG0842	Transport permease protein
E2R47_16595	COG3568	Endonuclease Exonuclease Phosphatase
E2R47_16600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E2R47_16605	COG0392	lysyltransferase activity
E2R47_16625	COG0670	Belongs to the BI1 family
E2R47_16630	COG0314	molybdopterin synthase activity
E2R47_16635	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
E2R47_16645	COG0521	Mo-molybdopterin cofactor biosynthetic process
E2R47_16705	COG1881	PFAM PEBP family protein
E2R47_16735	COG4677	pectinesterase activity
E2R47_16745	COG0561	phosphatase activity
E2R47_16755	COG4149	molybdate abc transporter
E2R47_16760	COG0725	ABC transporter, periplasmic molybdate-binding protein
E2R47_16770	COG3585	molybdate ion transport
E2R47_16770	COG2005	Transcriptional regulator
E2R47_16775	COG1119	ATPase activity
E2R47_16800	COG2017	converts alpha-aldose to the beta-anomer
E2R47_16810	COG1120	ATPase activity
E2R47_16815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E2R47_16825	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
E2R47_16830	COG5016	pyruvate
E2R47_16830	COG0511	ligase activity, forming carbon-carbon bonds
E2R47_16835	COG3630	sodium ion export across plasma membrane
E2R47_16840	COG0471	metal ion transport
E2R47_16840	COG0490	domain, Protein
E2R47_16845	COG0583	DNA-binding transcription factor activity
E2R47_16850	COG0583	DNA-binding transcription factor activity
E2R47_16855	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E2R47_16860	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E2R47_16860	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E2R47_16865	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E2R47_16875	COG1230	cation diffusion facilitator family transporter
E2R47_16915	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
E2R47_16920	COG2885	chlorophyll binding
E2R47_16930	COG3064	Membrane
E2R47_16935	COG0848	biopolymer transport protein
E2R47_16940	COG0811	peptide transport
E2R47_16945	COG0824	Thioesterase
E2R47_16950	COG3790	cyd operon protein YbgE
E2R47_16955	COG4890	Cyd operon protein YbgT
E2R47_16960	COG1294	oxidase, subunit
E2R47_16965	COG1271	oxidase subunit
E2R47_16970	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E2R47_16980	COG0508	dehydrogenase complex catalyzes the overall conversion of
E2R47_16985	COG0567	Dehydrogenase, E1 component
E2R47_17000	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
E2R47_17005	COG2009	succinate dehydrogenase
E2R47_17015	COG3180	Ammonia monooxygenase
E2R47_17030	COG1984	allophanate hydrolase subunit 2
E2R47_17035	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E2R47_17040	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
E2R47_17085	COG2205	protein histidine kinase activity
E2R47_17090	COG0745	RESPONSE REGULATOR receiver
E2R47_17100	COG1982	Orn Lys Arg decarboxylase major
E2R47_17105	COG0531	amino acid
E2R47_17115	COG0033	Phosphoglucomutase
E2R47_17125	COG0596	Alpha beta hydrolase
E2R47_17140	COG0735	belongs to the Fur family
E2R47_17145	COG0583	DNA-binding transcription factor activity
E2R47_17150	COG1053	succinate dehydrogenase
E2R47_17160	COG0477	Major facilitator Superfamily
E2R47_17190	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E2R47_17195	COG1846	Transcriptional regulator
E2R47_17195	COG1940	carbohydrate kinase activity
E2R47_17200	COG0647	UMP catabolic process
E2R47_17205	COG0367	asparagine synthase
E2R47_17250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E2R47_17260	COG1702	phosphate starvation-inducible protein PhoH
E2R47_17270	COG4535	Mg2 and Co2 transporter CorC
E2R47_17275	COG0815	Transfers the fatty acyl group on membrane lipoproteins
E2R47_17285	COG0765	amino acid transport
E2R47_17290	COG0765	amino acid transport
E2R47_17295	COG1126	abc transporter atp-binding protein
E2R47_17310	COG0443	Heat shock 70 kDa protein
E2R47_17315	COG2214	Heat shock protein DnaJ domain protein
E2R47_17325	COG2214	Heat shock protein DnaJ domain protein
E2R47_17340	COG2888	peptidyl-tyrosine sulfation
E2R47_17345	COG3829	transcription factor binding
E2R47_17345	COG3290	protein histidine kinase activity
E2R47_17375	COG1466	dna polymerase III delta subunit
E2R47_17395	COG0799	negative regulation of ribosome biogenesis
E2R47_17405	COG0768	penicillin binding
E2R47_17410	COG0772	Belongs to the SEDS family
E2R47_17415	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E2R47_17420	COG1686	Belongs to the peptidase S11 family
E2R47_17435	COG0583	DNA-binding transcription factor activity
E2R47_17450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E2R47_17460	COG1278	Cold shock
E2R47_17470	COG3069	C4-dicarboxylate transmembrane transporter activity
E2R47_17475	COG4565	transcriptional regulatory protein
E2R47_17480	COG3290	protein histidine kinase activity
E2R47_17485	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
E2R47_17490	COG3052	prosthetic group binding
E2R47_17495	COG2301	Belongs to the HpcH HpaI aldolase family
E2R47_17500	COG3051	citrate lyase alpha subunit
E2R47_17515	COG0471	metal ion transport
E2R47_17520	COG3719	Belongs to the RNase T2 family
E2R47_17525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E2R47_17530	COG1063	alcohol dehydrogenase
E2R47_17535	COG0589	response to stress
E2R47_17550	COG0243	molybdopterin cofactor binding
E2R47_17565	COG0450	alkyl hydroperoxide reductase
E2R47_17570	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E2R47_17580	COG0583	DNA-binding transcription factor activity
E2R47_17585	COG3969	phosphoadenosine phosphosulfate
E2R47_17590	COG1475	DNA binding
E2R47_17595	COG0436	Aminotransferase
E2R47_17600	COG0371	Dehydrogenase
E2R47_17605	COG2879	small protein
E2R47_17610	COG1966	Carbon starvation protein
E2R47_17620	COG1028	Short-chain dehydrogenase reductase Sdr
E2R47_17625	COG1535	isochorismatase
E2R47_17625	COG3433	isochorismatase activity
E2R47_17630	COG1021	2,3-dihydroxybenzoate-AMP ligase
E2R47_17635	COG1169	isochorismate synthase
E2R47_17640	COG4592	Periplasmic binding protein
E2R47_17650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E2R47_17655	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E2R47_17660	COG1120	ATPase activity
E2R47_17665	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
E2R47_17670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E2R47_17670	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
E2R47_17675	COG3251	PFAM MbtH domain protein
E2R47_17680	COG2382	esterase
E2R47_17685	COG4771	TonB-dependent receptor
E2R47_17690	COG2977	Belongs to the P-Pant transferase superfamily
E2R47_17695	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
E2R47_17715	COG2315	Protein conserved in bacteria
E2R47_17730	COG0668	transmembrane transport
E2R47_17735	COG1113	amino acid transport
E2R47_17745	COG3059	membrane
E2R47_17755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E2R47_17760	COG2207	Transcriptional regulator
E2R47_17765	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E2R47_17770	COG5002	protein histidine kinase activity
E2R47_17780	COG2246	polysaccharide biosynthetic process
E2R47_17785	COG0463	Glycosyl transferase, family 2
E2R47_17880	COG2501	S4 domain
E2R47_17885	COG1988	membrane-bound metal-dependent
E2R47_17905	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
E2R47_17915	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E2R47_17920	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
E2R47_17940	COG1464	Belongs to the NlpA lipoprotein family
E2R47_17950	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
E2R47_17955	COG4181	ATPase activity
E2R47_17960	COG2755	lipolytic protein G-D-S-L family
E2R47_17965	COG0300	oxidoreductase activity
E2R47_17970	COG3118	belongs to the thioredoxin family
E2R47_17975	COG0390	transport system, permease component
E2R47_17980	COG4619	ABC transporter
E2R47_17985	COG0330	HflC and HflK could
E2R47_17990	COG1585	Membrane protein implicated in regulation of membrane protease activity
E2R47_18000	COG2217	Heavy metal translocating P-type atpase
E2R47_18010	COG3735	TraB family
E2R47_18025	COG2223	nitrite transmembrane transporter activity
E2R47_18030	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E2R47_18030	COG4651	solute:proton antiporter activity
E2R47_18035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E2R47_18085	COG2832	Protein of unknown function (DUF454)
E2R47_18090	COG3923	Primosomal replication protein n
E2R47_18100	COG5464	transposase or invertase
E2R47_18105	COG3264	Mechanosensitive ion channel
E2R47_18105	COG1196	nuclear chromosome segregation
E2R47_18110	COG1309	transcriptional regulator
E2R47_18115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E2R47_18120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E2R47_18135	COG0110	maltose O-acetyltransferase activity
E2R47_18155	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E2R47_18165	COG3695	enzyme binding
E2R47_18170	COG3126	Type III secretion system lipoprotein chaperone (YscW)
E2R47_18175	COG1946	Acyl-CoA thioesterase
E2R47_18180	COG0004	ammonium transporteR
E2R47_18185	COG0347	Belongs to the P(II) protein family
E2R47_18190	COG1132	(ABC) transporter
E2R47_18195	COG1132	(ABC) transporter
E2R47_18200	COG1522	sequence-specific DNA binding
E2R47_18210	COG0561	phosphatase activity
E2R47_18215	COG4533	DNA binding
E2R47_18225	COG0824	Thioesterase
E2R47_18230	COG1555	photosystem II stabilization
E2R47_18235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E2R47_18240	COG0776	regulation of translation
E2R47_18245	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
E2R47_18270	COG0271	Belongs to the BolA IbaG family
E2R47_18275	COG3056	Lipoprotein
E2R47_18280	COG2223	nitrite transmembrane transporter activity
E2R47_18285	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E2R47_18290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E2R47_18295	COG1845	cytochrome c oxidase, subunit III
E2R47_18300	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
E2R47_18325	COG2814	Major facilitator Superfamily
E2R47_18355	COG2188	Transcriptional regulator
E2R47_18390	COG0142	geranyltranstransferase activity
E2R47_18400	COG0667	Aldo Keto reductase
E2R47_18405	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
E2R47_18410	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
E2R47_18425	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E2R47_18425	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E2R47_18435	COG4238	major outer membrane lipoprotein
E2R47_18440	COG3248	Nucleoside-binding outer membrane protein
E2R47_18455	COG1403	HNH endonuclease
E2R47_18470	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E2R47_18480	COG1862	Preprotein translocase
E2R47_18500	COG0450	alkyl hydroperoxide reductase
E2R47_18510	COG0366	Alpha amylase catalytic
E2R47_18520	COG1114	Component of the transport system for branched-chain amino acids
E2R47_18525	COG5002	protein histidine kinase activity
E2R47_18535	COG0420	3'-5' exonuclease activity
E2R47_18540	COG0419	ATPase involved in DNA repair
E2R47_18545	COG2814	Major facilitator Superfamily
E2R47_18550	COG1940	carbohydrate kinase activity
E2R47_18565	COG4126	flavin adenine dinucleotide binding
E2R47_18585	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
E2R47_18590	COG3706	GGDEF domain
E2R47_18615	COG1181	Belongs to the D-alanine--D-alanine ligase family
E2R47_18635	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
E2R47_18645	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E2R47_18660	COG0113	porphobilinogen synthase activity
E2R47_18695	COG1280	lysine exporter protein (LysE YggA)
E2R47_18715	COG1294	oxidase, subunit
E2R47_18720	COG1271	oxidase subunit
E2R47_18740	COG2814	Major facilitator Superfamily
E2R47_18750	COG0789	Transcriptional regulator
E2R47_18755	COG2217	Heavy metal translocating P-type atpase
E2R47_18770	COG1538	Outer membrane efflux protein
E2R47_18805	COG2200	EAL domain
E2R47_18820	COG3539	Fimbrial protein
E2R47_18825	COG3121	Chaperone
E2R47_18830	COG3188	usher protein
E2R47_18865	COG0179	Fumarylacetoacetate (FAA) hydrolase
E2R47_18880	COG2814	Major facilitator Superfamily
E2R47_18905	COG0582	viral genome integration into host DNA
E2R47_18925	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E2R47_18945	COG2195	Cleaves the N-terminal amino acid of tripeptides
E2R47_18950	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E2R47_18955	COG1690	Belongs to the RtcB family
E2R47_18965	COG3034	peptidoglycan biosynthetic process
E2R47_18970	COG0121	glutamine amidotransferase
E2R47_18985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E2R47_19075	COG3209	COG3209 Rhs family protein
E2R47_19090	COG3209	COG3209 Rhs family protein
E2R47_19100	COG3501	Rhs element vgr protein
E2R47_19135	COG2885	chlorophyll binding
E2R47_19135	COG3047	cAMP biosynthetic process
E2R47_19230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E2R47_19240	COG2226	methyltransferase
E2R47_19250	COG0741	lytic transglycosylase activity
E2R47_19250	COG1388	LysM domain
E2R47_19255	COG2226	methyltransferase
E2R47_19265	COG2814	Major facilitator Superfamily
E2R47_19270	COG0583	DNA-binding transcription factor activity
E2R47_19275	COG0656	L-ascorbic acid biosynthetic process
E2R47_19310	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E2R47_19335	COG1720	tRNA m6t6A37 methyltransferase activity
E2R47_19345	COG3015	lipoprotein NlpE involved in copper resistance
E2R47_19350	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E2R47_19355	COG4681	YaeQ
E2R47_19365	COG4568	rho-dependent transcription termination
E2R47_19375	COG0346	lactoylglutathione lyase activity
E2R47_19440	COG0575	Belongs to the CDS family
E2R47_19480	COG0024	Methionine aminopeptidase
E2R47_19495	COG0477	Major facilitator Superfamily
E2R47_19505	COG3835	regulator
E2R47_19530	COG2860	membrane
E2R47_19555	COG3539	Fimbrial protein
E2R47_19560	COG3539	Fimbrial protein
E2R47_19565	COG3539	Fimbrial protein
E2R47_19570	COG3121	Chaperone
E2R47_19575	COG3188	usher protein
E2R47_19595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E2R47_19600	COG1120	ATPase activity
E2R47_19605	COG4774	siderophore transport
E2R47_19610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E2R47_19615	COG1643	Atp-dependent helicase
E2R47_19620	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
E2R47_19630	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E2R47_19640	COG0617	tRNA 3'-terminal CCA addition
E2R47_19645	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E2R47_19665	COG0726	polysaccharide deacetylase
E2R47_19670	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E2R47_19690	COG3539	Fimbrial protein
E2R47_19695	COG0842	Transport permease protein
E2R47_19700	COG1131	(ABC) transporter
E2R47_19705	COG0288	reversible hydration of carbon dioxide
E2R47_19715	COG4993	Dehydrogenase
E2R47_19740	COG1349	DNA-binding transcription factor activity
E2R47_19780	COG3064	Membrane
E2R47_19795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E2R47_19800	COG0508	dehydrogenase complex catalyzes the overall conversion of
E2R47_19805	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
E2R47_19810	COG2186	Transcriptional regulator
E2R47_19815	COG1113	amino acid transport
E2R47_19820	COG2211	Major facilitator Superfamily
E2R47_19825	COG3940	Belongs to the glycosyl hydrolase 43 family
E2R47_19830	COG3725	Membrane protein required for beta-lactamase induction
E2R47_19850	COG4969	Belongs to the N-Me-Phe pilin family
E2R47_19855	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E2R47_19860	COG1459	type II secretion system
E2R47_19870	COG0237	dephospho-CoA kinase activity
E2R47_19885	COG0583	DNA-binding transcription factor activity
E2R47_19890	COG0667	Aldo Keto reductase
E2R47_19895	COG0494	nUDIX hydrolase
E2R47_19915	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E2R47_19920	COG0849	cell division
E2R47_19930	COG1181	Belongs to the D-alanine--D-alanine ligase family
E2R47_19945	COG0772	Belongs to the SEDS family
E2R47_19960	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E2R47_19970	COG0768	penicillin binding
E2R47_19990	COG1609	Transcriptional regulator
E2R47_20045	COG4143	(ABC) transporter
E2R47_20050	COG1178	ABC-type Fe3 transport system permease component
E2R47_20060	COG0586	Pfam SNARE associated Golgi protein
E2R47_20100	COG0417	DNA replication proofreading
E2R47_20130	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
E2R47_20185	COG2271	Major facilitator Superfamily
E2R47_20195	COG0644	oxidoreductase
E2R47_20250	COG0505	Belongs to the CarA family
E2R47_20315	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
E2R47_20345	COG1047	Peptidyl-prolyl cis-trans
E2R47_20360	COG0196	riboflavin kinase activity
E2R47_20385	COG0583	DNA-binding transcription factor activity
E2R47_20405	COG0641	radical SAM
E2R47_20410	COG3119	arylsulfatase activity
E2R47_20420	COG0737	Belongs to the 5'-nucleotidase family
E2R47_20435	COG0583	DNA-binding transcription factor activity
E2R47_20455	COG3121	Chaperone
E2R47_20460	COG3539	Fimbrial protein
E2R47_20475	COG3188	usher protein
E2R47_20485	COG3539	Fimbrial protein
E2R47_20540	COG4735	regulation of single-species biofilm formation
E2R47_20545	COG1584	GPR1 FUN34 yaaH family protein
E2R47_20550	COG0521	Mo-molybdopterin cofactor biosynthetic process
E2R47_20560	COG1115	amino acid carrier protein
E2R47_20570	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E2R47_20580	COG0460	homoserine dehydrogenase
E2R47_20580	COG0527	aspartate kinase activity
E2R47_20590	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
E2R47_20600	COG0745	RESPONSE REGULATOR receiver
E2R47_20620	COG3121	Chaperone
E2R47_20640	COG4452	Inner membrane protein CreD
E2R47_20645	COG2205	protein histidine kinase activity
E2R47_20650	COG0745	RESPONSE REGULATOR receiver
E2R47_20655	COG3045	CreA protein
E2R47_20660	COG2207	Transcriptional regulator
E2R47_20660	COG3708	Transcriptional regulator
E2R47_20690	COG0488	(ABC) transporter
E2R47_20705	COG0560	Phosphoserine phosphatase
E2R47_20715	COG3726	membrane protein affecting hemolysin expression
E2R47_20725	COG1943	Transposase
E2R47_20750	COG1328	CTP reductase activity
E2R47_20755	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E2R47_20760	COG0084	hydrolase, TatD family'
E2R47_20765	COG4667	esterase of the alpha-beta hydrolase superfamily
E2R47_20775	COG2823	Periplasmic or secreted lipoprotein
E2R47_20785	COG1011	Hydrolase
E2R47_20795	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
E2R47_20825	COG3706	GGDEF domain
E2R47_20830	COG4114	ferric iron reductase
E2R47_20835	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E2R47_20840	COG2197	response regulator
E2R47_20845	COG2197	response regulator
E2R47_20850	COG2966	Psort location CytoplasmicMembrane, score
E2R47_20865	COG1484	DNA-dependent DNA replication
E2R47_20880	COG0840	transmembrane signaling receptor activity
E2R47_20885	COG1966	Carbon starvation protein
E2R47_20890	COG2879	small protein
E2R47_20895	COG0523	cobalamin synthesis protein
E2R47_20905	COG1280	lysine exporter protein (LysE YggA)
E2R47_20910	COG3586	endonuclease activity
E2R47_20925	COG1012	belongs to the aldehyde dehydrogenase family
E2R47_20930	COG5464	transposase or invertase
E2R47_20935	COG2814	Major facilitator Superfamily
E2R47_20940	COG2733	membrane
E2R47_20945	COG0477	Major facilitator Superfamily
E2R47_20950	COG3366	ferrous iron transmembrane transporter activity
E2R47_20955	COG0700	Nucleoside recognition
E2R47_20960	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E2R47_20965	COG0583	DNA-binding transcription factor activity
E2R47_20985	COG2186	Transcriptional regulator
E2R47_20990	COG0412	Dienelactone hydrolase
E2R47_21025	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
E2R47_21190	COG0582	viral genome integration into host DNA
E2R47_21200	COG1064	alcohol dehydrogenase
E2R47_21205	COG3265	gluconokinase activity
E2R47_21210	COG1063	alcohol dehydrogenase
E2R47_21215	COG1028	Short-chain dehydrogenase reductase Sdr
E2R47_21220	COG2610	gluconate transmembrane transporter activity
E2R47_21225	COG1609	Transcriptional regulator
E2R47_21230	COG0795	lipopolysaccharide-transporting ATPase activity
E2R47_21235	COG0795	lipopolysaccharide-transporting ATPase activity
E2R47_21250	COG2927	DNA polymerase III (CHI subunit)
E2R47_21280	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
E2R47_21290	COG2731	YhcH YjgK YiaL family protein
E2R47_21315	COG1288	antiporter activity
E2R47_21320	COG1438	arginine binding
E2R47_21365	COG1263	PTS System
E2R47_21365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E2R47_21370	COG0366	Alpha amylase catalytic
E2R47_21385	COG2026	Addiction module toxin, RelE StbE family
E2R47_21390	COG3077	Addiction module antitoxin, RelB DinJ family
E2R47_21395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E2R47_21395	COG3711	transcriptional antiterminator
E2R47_21410	COG3964	amidohydrolase
E2R47_21440	COG3783	Cytochrome b(562)
E2R47_21445	COG0312	modulator of DNA gyrase
E2R47_21455	COG1082	Xylose isomerase domain protein TIM barrel
E2R47_21465	COG2814	Major facilitator Superfamily
E2R47_21470	COG0673	inositol 2-dehydrogenase activity
E2R47_21475	COG3962	Belongs to the TPP enzyme family
E2R47_21480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E2R47_21490	COG1082	Xylose isomerase domain protein TIM barrel
E2R47_21495	COG5520	Belongs to the glycosyl hydrolase 30 family
E2R47_21525	COG3718	enzyme involved in inositol metabolism
E2R47_21530	COG0477	Major facilitator Superfamily
E2R47_21530	COG2814	Major facilitator Superfamily
E2R47_21540	COG0477	Major facilitator Superfamily
E2R47_21540	COG2814	Major facilitator Superfamily
E2R47_21545	COG1737	Transcriptional regulator
E2R47_21545	COG0837	glucose binding
E2R47_21555	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E2R47_21565	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
E2R47_21570	COG3964	amidohydrolase
E2R47_21575	COG2271	Major facilitator Superfamily
E2R47_21580	COG2105	PFAM AIG2 family protein
E2R47_21600	COG1253	flavin adenine dinucleotide binding
E2R47_21610	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
E2R47_21630	COG1733	regulation of RNA biosynthetic process
E2R47_21635	COG0702	epimerase
E2R47_21640	COG0697	spore germination
E2R47_21650	COG1113	amino acid transport
E2R47_21655	COG0545	Peptidyl-prolyl cis-trans isomerase
E2R47_21660	COG3061	Opacity-associated protein A
E2R47_21695	COG3477	response to acidic pH
E2R47_21740	COG1073	alpha beta
E2R47_21745	COG3650	response to hydrogen peroxide
E2R47_21755	COG1960	acyl-CoA dehydrogenase activity
E2R47_21760	COG0754	glutathionylspermidine amidase activity
E2R47_21765	COG5463	Belongs to the UPF0441 family
E2R47_21770	COG3766	membrane
E2R47_21780	COG1842	Phage shock protein A
E2R47_21785	COG3789	protein conserved in bacteria
E2R47_21795	COG0557	exoribonuclease II activity
E2R47_21815	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
E2R47_21820	COG0330	HflC and HflK could
E2R47_21825	COG0330	HflC and HflK could
E2R47_21830	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E2R47_21855	COG0802	atpase or kinase
E2R47_21860	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
E2R47_21860	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E2R47_21885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E2R47_21905	COG1511	domain protein
E2R47_21905	COG3264	Mechanosensitive ion channel
E2R47_21910	COG0531	amino acid
E2R47_21920	COG1053	succinate dehydrogenase
E2R47_21925	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E2R47_21945	COG2076	Multidrug Resistance protein
E2R47_21955	COG5510	response to toxic substance
E2R47_22000	COG0531	amino acid
E2R47_22005	COG3030	protein affecting phage T7 exclusion by the F plasmid
E2R47_22010	COG1027	Aspartate ammonia-lyase
E2R47_22015	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E2R47_22030	COG1309	transcriptional regulator
E2R47_22050	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
E2R47_22050	COG3933	PFAM sigma-54 factor interaction domain-containing protein
E2R47_22055	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E2R47_22060	COG1063	alcohol dehydrogenase
E2R47_22065	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
E2R47_22070	COG1063	alcohol dehydrogenase
E2R47_22075	COG3716	PTS system mannose fructose sorbose family IID component
E2R47_22085	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E2R47_22090	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E2R47_22090	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E2R47_22135	COG2197	response regulator
E2R47_22140	COG1132	(ABC) transporter
E2R47_22160	COG3381	protein complex oligomerization
E2R47_22165	COG3302	dmso reductase anchor subunit
E2R47_22170	COG0437	4 iron, 4 sulfur cluster binding
E2R47_22175	COG0243	molybdopterin cofactor binding
E2R47_22180	COG3290	protein histidine kinase activity
E2R47_22185	COG4565	transcriptional regulatory protein
E2R47_22195	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E2R47_22200	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E2R47_22200	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E2R47_22215	COG2169	Transcriptional regulator
E2R47_22220	COG1982	Orn Lys Arg decarboxylase major
E2R47_22225	COG2207	Transcriptional regulator
E2R47_22230	COG0531	amino acid
E2R47_22260	COG2824	Alkylphosphonate utilization operon protein PhnA
E2R47_22265	COG2764	glyoxalase bleomycin resistance protein dioxygenase
E2R47_22285	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
E2R47_22295	COG1301	dicarboxylic acid transport
E2R47_22300	COG4235	cytochrome complex assembly
E2R47_22305	COG3088	subunit of a heme lyase
E2R47_22310	COG1138	Cytochrome C-type biogenesis protein
E2R47_22315	COG3301	Polysulphide reductase, NrfD
E2R47_22320	COG0437	4 iron, 4 sulfur cluster binding
E2R47_22325	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
E2R47_22335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E2R47_22340	COG3162	membrane
E2R47_22350	COG1346	cytolysis
E2R47_22355	COG1380	Effector of murein hydrolase LrgA
E2R47_22360	COG0583	DNA-binding transcription factor activity
E2R47_22365	COG0025	NhaP-type Na H and K H
E2R47_22375	COG2252	PERMEase
E2R47_22385	COG0789	Transcriptional regulator
E2R47_22395	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E2R47_22435	COG0629	single-stranded DNA binding
E2R47_22445	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
E2R47_22460	COG2315	Protein conserved in bacteria
E2R47_22465	COG0432	Pfam Uncharacterised protein family UPF0047
E2R47_22470	COG3700	Belongs to the class B bacterial acid phosphatase family
E2R47_22480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
E2R47_22485	COG0305	Participates in initiation and elongation during chromosome replication
E2R47_22510	COG0735	belongs to the Fur family
E2R47_22515	COG3237	CsbD-like
E2R47_22525	COG0534	Mate efflux family protein
E2R47_22535	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
E2R47_22580	COG3833	ABC-type maltose transport systems, permease component
E2R47_22590	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E2R47_22615	COG0527	aspartate kinase activity
E2R47_22700	COG2246	polysaccharide biosynthetic process
E2R47_22730	COG5301	cellulose 1,4-beta-cellobiosidase activity
E2R47_22770	COG3122	Protein conserved in bacteria
E2R47_22815	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
E2R47_22855	COG0151	Belongs to the GarS family
E2R47_22880	COG0776	regulation of translation
E2R47_22885	COG3068	Protein conserved in bacteria
E2R47_22920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E2R47_22925	COG2104	thiamine diphosphate biosynthetic process
E2R47_22990	COG0250	Participates in transcription elongation, termination and antitermination
E2R47_22995	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E2R47_23105	COG0583	DNA-binding transcription factor activity
E2R47_23145	COG2207	Transcriptional regulator
E2R47_23155	COG0371	Dehydrogenase
E2R47_23160	COG3738	Protein conserved in bacteria
E2R47_23175	COG0737	Belongs to the 5'-nucleotidase family
E2R47_23190	COG0668	transmembrane transport
E2R47_23195	COG0460	homoserine dehydrogenase
E2R47_23195	COG0527	aspartate kinase activity
E2R47_23200	COG0626	cystathionine gamma-synthase activity
E2R47_23225	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E2R47_23230	COG1609	Transcriptional regulator
E2R47_23235	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E2R47_23250	COG1575	Belongs to the MenA family. Type 1 subfamily
E2R47_23265	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E2R47_23275	COG1494	fructose-1,6-bisphosphatase
E2R47_23285	COG3152	Membrane
E2R47_23340	COG1070	Carbohydrate kinase
E2R47_23360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E2R47_23375	COG2211	Major facilitator Superfamily
E2R47_23400	COG3678	ATP-independent chaperone mediated protein folding
E2R47_23405	COG0745	RESPONSE REGULATOR receiver
E2R47_23410	COG2205	protein histidine kinase activity
E2R47_23420	COG2258	MOSC domain
E2R47_23425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
E2R47_23435	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E2R47_23445	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
E2R47_23480	COG1454	alcohol dehydrogenase
E2R47_23495	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
E2R47_23520	COG3383	formate dehydrogenase (NAD+) activity
E2R47_23520	COG0243	molybdopterin cofactor binding
E2R47_23525	COG0243	molybdopterin cofactor binding
E2R47_23525	COG3383	formate dehydrogenase (NAD+) activity
E2R47_23530	COG0437	4 iron, 4 sulfur cluster binding
E2R47_23535	COG2864	formate dehydrogenase
E2R47_23550	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
E2R47_23560	COG4680	protein conserved in bacteria
E2R47_23565	COG5499	transcription regulator containing HTH domain
E2R47_23570	COG0456	acetyltransferase
E2R47_23585	COG1011	Hydrolase
E2R47_23590	COG1349	DNA-binding transcription factor activity
E2R47_23595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E2R47_23605	COG3684	Belongs to the aldolase LacD family
E2R47_23615	COG2017	converts alpha-aldose to the beta-anomer
E2R47_23620	COG1501	Belongs to the glycosyl hydrolase 31 family
E2R47_23665	COG0561	phosphatase activity
E2R47_23675	COG0174	glutamine synthetase
E2R47_23685	COG3852	Histidine kinase
E2R47_23700	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E2R47_23735	COG0204	Acyl-transferase
E2R47_23750	COG3084	Protein conserved in bacteria
E2R47_23755	COG0746	molybdenum cofactor guanylyltransferase activity
E2R47_23760	COG1763	Mo-molybdopterin cofactor biosynthetic process
E2R47_23800	COG1739	Uncharacterized protein family UPF0029
E2R47_23830	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
E2R47_23845	COG0805	protein transport
E2R47_23855	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E2R47_23875	COG1322	Protein conserved in bacteria
E2R47_23880	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
E2R47_23890	COG0641	radical SAM
E2R47_23905	COG0583	DNA-binding transcription factor activity
E2R47_23910	COG0697	spore germination
E2R47_23915	COG0561	phosphatase activity
E2R47_23920	COG2267	carboxylic ester hydrolase activity
E2R47_23925	COG1280	lysine exporter protein (LysE YggA)
E2R47_23930	COG1280	lysine exporter protein (LysE YggA)
E2R47_23940	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
E2R47_23945	COG2050	protein possibly involved in aromatic compounds catabolism
E2R47_23980	COG1011	Hydrolase
E2R47_24000	COG5567	small periplasmic lipoprotein
E2R47_24035	COG3072	Adenylate cyclase
E2R47_24050	COG2959	enzyme of heme biosynthesis
E2R47_24055	COG3071	HemY protein
E2R47_24080	COG1113	amino acid transport
E2R47_24100	COG2244	polysaccharide biosynthetic process
E2R47_24105	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E2R47_24110	COG0456	acetyltransferase
E2R47_24115	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E2R47_24115	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E2R47_24120	COG1088	dTDP-glucose 4,6-dehydratase activity
E2R47_24125	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E2R47_24145	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
E2R47_24155	COG3118	belongs to the thioredoxin family
E2R47_24190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E2R47_24200	COG0583	DNA-binding transcription factor activity
E2R47_24225	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E2R47_24230	COG3978	acetolactate synthase activity
E2R47_24295	COG2186	Transcriptional regulator
E2R47_24300	COG0477	Major facilitator Superfamily
E2R47_24305	COG1609	Transcriptional regulator
E2R47_24310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E2R47_24315	COG1879	ABC-type sugar transport system periplasmic component
E2R47_24320	COG1172	Belongs to the binding-protein-dependent transport system permease family
E2R47_24355	COG1522	sequence-specific DNA binding
E2R47_24360	COG0716	FMN binding
E2R47_24380	COG3312	ion transport
E2R47_24445	COG4533	DNA binding
E2R47_24450	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
E2R47_24455	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
E2R47_24455	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E2R47_24455	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E2R47_24460	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E2R47_24465	COG0573	inorganic phosphate transmembrane transporter activity
E2R47_24470	COG0581	inorganic phosphate transmembrane transporter activity
E2R47_24480	COG0704	Plays a role in the regulation of phosphate uptake
E2R47_24485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E2R47_24490	COG2252	PERMEase
E2R47_24495	COG0431	NADPH-dependent FMN reductase
E2R47_24500	COG2091	lysine biosynthetic process via aminoadipic acid