locus-tag class description CXL13_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) CXL13_00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CXL13_00030 ENOG4105CXK mandelate racemase muconate lactonizing CXL13_00035 ENOG4105DJB Major Facilitator Superfamily CXL13_00040 ENOG410667J hydrolase CXL13_00045 ENOG4105EMF GntR family transcriptional regulator CXL13_00050 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 CXL13_00055 ENOG4108RTU Aldolase CXL13_00065 ENOG4105DJB Major Facilitator Superfamily CXL13_00070 ENOG4105BZU Histidine kinase CXL13_00075 ENOG4108SV3 Tmao reductase system periplasmic protein tort CXL13_00080 ENOG4106WF9 DNA-binding transcriptional regulator TorR CXL13_00085 ENOG4105CUW cytochrome C-TYPE protein CXL13_00090 ENOG4108EM1 reductase CXL13_00100 ENOG4105CA0 peroxidase CXL13_00110 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) CXL13_00115 ENOG41060IM Heme exporter protein CXL13_00120 ENOG4105X3C heme exporter protein CXL13_00125 ENOG4108ZKK Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity) CXL13_00130 ENOG4105DA4 cytochrome c-type biogenesis protein CXL13_00135 ENOG4107QX9 Thiol disulfide interChange protein CXL13_00140 ENOG4105KWW Biogenesis protein CXL13_00145 ENOG4105D99 atp gtp-binding protein CXL13_00150 ENOG4105R2A (LipO)protein CXL13_00160 ENOG4108SHS Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK DnaJ GrpE. Its activity is ATP- independent (By similarity) CXL13_00170 ENOG4105VG5 Membrane CXL13_00175 ENOG4105JP4 Inner membrane protein yidG CXL13_00180 ENOG4105J13 transcriptional regulator CXL13_00195 ENOG4105W8I Transcriptional regulator CXL13_00205 ENOG4105E5M Multidrug resistance protein D CXL13_00235 ENOG4105C7K acetolactate synthase CXL13_00240 ENOG4105M71 acetolactate synthase 1 regulatory subunit CXL13_00245 ENOG4107FB0 transcriptional regulator DeoR family CXL13_00250 ENOG4108RVA ribokinase CXL13_00255 ENOG4105EDR glucose galactose transporter CXL13_00265 ENOG4108KX4 response regulator CXL13_00270 ENOG4105BZU Histidine kinase CXL13_00275 ENOG4105CXY transporter CXL13_00280 ENOG4105CXY transporter CXL13_00285 ENOG4108SAJ Protein of unknown function (DUF1198) CXL13_00290 ENOG4105FDP GntR family transcriptional regulator CXL13_00300 ENOG41090UW PTS System CXL13_00305 ENOG4105DT3 PTS system, galactitol-specific IIc component CXL13_00315 ENOG4105D2N Aldolase CXL13_00340 ENOG4105CS2 ec 3.2.1.21 CXL13_00345 ENOG4105T8A Uncharacterized protein YicS CXL13_00360 ENOG4108EQA pts system CXL13_00365 ENOG4105ETZ PTS System CXL13_00370 ENOG4105F3R pts system mannose fructose sorbose family iid CXL13_00385 ENOG4105DNE Transposase CXL13_00390 ENOG4108UZ3 Transporter CXL13_00400 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic CXL13_00415 ENOG4105CHJ isochorismatase hydrolase CXL13_00430 ENOG4105TNG K13735 adhesin invasin CXL13_00445 ENOG4108TC1 Transcriptional regulator CXL13_00450 ENOG4105FV3 CXL13_00460 ENOG4105ISV protein with bipartite regulator domain CXL13_00495 ENOG4105CT4 transporter CXL13_00500 ENOG4105CJQ hydrolase, family 31 CXL13_00505 ENOG4105JV1 AsmA family CXL13_00510 ENOG4105C2W permease CXL13_00515 ENOG4105D6U Sodium Glutamate Symporter CXL13_00525 ENOG4105CB5 ATP-dependent DNA helicase recG CXL13_00530 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase CXL13_00535 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) CXL13_00540 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) CXL13_00555 ENOG4105EN6 Membrane CXL13_00605 ENOG4105DSJ YicC domain protein CXL13_00635 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase CXL13_00650 ENOG4105W0E 50S ribosomal protein L33 CXL13_00665 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase CXL13_00670 ENOG4105DKP glycosyl transferase, family 9 CXL13_00675 ENOG4107RJ7 Glycosyl transferase (Group 1 CXL13_00680 ENOG4107543 (lipo)polysaccharide CXL13_00690 ENOG4107XU6 Glycosyl transferase (Group 1 CXL13_00695 ENOG4106AH0 Glycosyl Transferase CXL13_00700 ENOG4105X1N Glycosyl transferase family 8 CXL13_00705 ENOG4108PDR lipopolysaccharide core biosynthesis protein CXL13_00710 ENOG4108QD8 lipopolysaccharide core biosynthesis protein CXL13_00715 ENOG4107XB0 Lipopolysaccharide 1,2-N-acetylglucosaminetransferase CXL13_00720 ENOG4108FRV O-antigen ligase CXL13_00725 ENOG4105D16 lipopolysaccharide heptosyltransferase i CXL13_00730 ENOG4105XA0 heptosyltransferase ii CXL13_00740 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) CXL13_00750 ENOG4105K64 Glycosyl transferase, family 2 CXL13_00755 ENOG4105PXI polysaccharide deacetylase CXL13_00760 ENOG41063SB peptidase CXL13_00770 ENOG4107YZP Rhodanese domain protein CXL13_00775 ENOG4105VW4 glutaredoxin 3 CXL13_00790 ENOG4105D7W serine acetyltransferase CXL13_00795 ENOG4105DJB Major Facilitator Superfamily CXL13_00800 ENOG4105DIA mandelate racemase muconate lactonizing CXL13_00810 ENOG4105ETE Transcriptional regulator (LacI family CXL13_00815 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) CXL13_00825 ENOG41073TP transcriptional regulator CXL13_00830 ENOG4105DAA L-lactate CXL13_00835 ENOG4105EUR Domain-Containing protein CXL13_00840 ENOG4108WY4 inner membrane lipoprotein CXL13_00845 ENOG4108YYI Protein of unknown function (DUF2810) CXL13_00855 ENOG4105E61 Mannitol repressor protein CXL13_00865 ENOG4105CTS PTS system mannitol-specific CXL13_00870 ENOG4108U78 Glutathione S-transferase CXL13_00880 ENOG4105EM7 Selenocysteine-specific translation elongation factor CXL13_00885 ENOG41066F8 ROK family CXL13_00890 ENOG4105C26 Dehydrogenase CXL13_00905 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase CXL13_00910 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase CXL13_00915 ENOG4105H6Q decarboxylase CXL13_00920 ENOG4105CMG Carbohydrate kinase CXL13_00925 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit CXL13_00930 ENOG4105CG6 trap dicarboxylate transporter dctm subunit CXL13_00935 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter CXL13_00940 ENOG4108M5W CXL13_00945 ENOG4108R66 Conserved Protein CXL13_00955 ENOG4105J4Q Transcriptional regulator CXL13_00960 ENOG4108XIB electron transport protein ysaA CXL13_00965 ENOG4105JKW Valine--pyruvate aminotransferase CXL13_00970 ENOG4107T9C Alpha amylase catalytic region CXL13_00975 ENOG4108UR8 BAX protein CXL13_00980 ENOG4105T16 Transcriptional regulator (AraC family) CXL13_00995 ENOG4105CMG Carbohydrate kinase CXL13_01000 ENOG410688U Inner membrane protein yiaB CXL13_01005 ENOG4105MEV Acyl-transferase CXL13_01015 ENOG4105RGS lipoprotein ysaB CXL13_01030 ENOG4105DQ6 Transposase CXL13_01040 ENOG4105CA9 Pyruvate kinase CXL13_01050 ENOG4105CPF Cell wall formation (By similarity) CXL13_01055 ENOG4105D1Z hydroxypyruvate reductase CXL13_01060 ENOG4105CSP Major Facilitator Superfamily CXL13_01065 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) CXL13_01085 ENOG4105VEQ Cold shock protein CXL13_01090 ENOG4105MVF Transcriptional regulator CXL13_01095 ENOG4106JH6 (LipO)protein CXL13_01105 ENOG4108ZG0 Ompa motb domain protein CXL13_01110 ENOG4107QY8 reductase CXL13_01115 ENOG4105HNP -acetyltransferase CXL13_01120 ENOG4108R3E Dna-3-methyladenine glycosylase i CXL13_01125 ENOG4105EAX Putative lipase CXL13_01130 ENOG4106EAR Fimbrial protein CXL13_01135 ENOG4108VCD Chaperone CXL13_01140 ENOG4105CW0 outer membrane usher protein CXL13_01145 ENOG4105MHR Fimbrial protein CXL13_01150 ENOG4106UCC Fimbrial protein CXL13_01155 ENOG4105DIJ Phosphoethanolamine transferase CXL13_01190 ENOG4105DEF Extracellular solute-binding protein, family 5 CXL13_01195 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CXL13_01200 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CXL13_01205 ENOG4105C3U ABC transporter CXL13_01210 ENOG4108JQ7 (ABC) transporter CXL13_01215 ENOG4105C44 Serine transporter CXL13_01230 ENOG4105D1V cellulose synthase operon protein YhjU CXL13_01235 ENOG410675P Celllulose biosynthesis operon protein BcsF YhjT CXL13_01245 ENOG410661M cytoplasmic protein CXL13_01250 ENOG4105UTS cellulose synthase operon protein YhjQ CXL13_01255 ENOG4107QZ7 Cellulose synthase catalytic subunit CXL13_01260 ENOG4107EEX Cellulose synthase regulator protein CXL13_01265 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) CXL13_01270 ENOG4105EJG cellulose synthase CXL13_01280 ENOG4105BZU Histidine kinase CXL13_01290 ENOG4105CS0 peptidase CXL13_01295 ENOG4107SS6 2-dehydro-3-deoxygluconokinase CXL13_01300 ENOG4105CMB EAL domain-containing protein CXL13_01305 ENOG41066T0 asmA family CXL13_01310 ENOG4105CSH Transporter CXL13_01315 ENOG4107H3J ribonuclease CXL13_01320 ENOG4105CBN LysR family transcriptional regulator CXL13_01325 ENOG4106S2D Transcriptional regulator CXL13_01345 ENOG4105FDP GntR family transcriptional regulator CXL13_01350 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine CXL13_01355 ENOG4108KPW sugar kinase CXL13_01360 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CXL13_01375 ENOG4105DC8 reductase CXL13_01380 ENOG4105D6S protein involved in catabolism of external DNA CXL13_01390 ENOG410657R replicase EC 2.7 CXL13_01395 ENOG4105DGW oligopeptidase A CXL13_01405 ENOG4105DUX Transporter CXL13_01410 ENOG4108M6U Universal stress protein A CXL13_01420 ENOG4105CJ3 phosphate transporter CXL13_01425 ENOG4105CBX hi0933 family CXL13_01490 ENOG410624V efflux system protein CXL13_01520 ENOG4105DR5 peptidase CXL13_01530 ENOG4105E3B Multicopper oxidase CXL13_01535 ENOG4105VR0 copper resistance CXL13_01540 ENOG4105JDN Copper resistance protein CXL13_01545 ENOG4108PG2 copper resistance CXL13_01550 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CXL13_01555 ENOG4105GR3 Histidine kinase CXL13_01565 ENOG4105D0S secretion protein (HlyD CXL13_01570 ENOG4105CJ1 ABC, transporter CXL13_01575 ENOG4105CMI transporter CXL13_01585 ENOG4107YAK holo-(acyl carrier protein) synthase 2 CXL13_01590 ENOG4105DSF transport protein CXL13_01600 ENOG4108W1V Lipoprotein CXL13_01605 ENOG4105EX9 Membrane CXL13_01615 ENOG4105C8Q Methyl-accepting chemotaxis CXL13_01625 ENOG4107FS9 Membrane CXL13_01635 ENOG4105MG3 Membrane CXL13_01640 ENOG4106H78 methyltransferase CXL13_01645 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) CXL13_01650 ENOG4105CAK Cell division ATP-binding protein ftsE CXL13_01655 ENOG4105CRP Part of the ABC transporter FtsEX involved in CXL13_01665 ENOG4105CP9 extracellular ligand-binding receptor CXL13_01670 ENOG4105U59 -acetyltransferase CXL13_01675 ENOG4105CP9 extracellular ligand-binding receptor CXL13_01680 ENOG4105C32 Amino acid ABC transporter (Permease) CXL13_01685 ENOG4105CF8 branched-chain amino acid ABC transporter, permease CXL13_01690 ENOG4105C0Z ABC transporter CXL13_01695 ENOG4108IV0 ABC, transporter CXL13_01700 ENOG41060M8 Pfam:PhdYeFM CXL13_01710 ENOG4105BZ7 extracellular solute-binding protein family 1 CXL13_01715 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component CXL13_01725 ENOG4108IJ9 (ABC) transporter CXL13_01730 ENOG4107T6V glycerophosphoryl diester phosphodiesterase CXL13_01735 ENOG4105WC8 Conserved Protein CXL13_01740 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) CXL13_01745 ENOG41080QX K07048 phosphotriesterase-related protein CXL13_01760 ENOG4108RVA ribokinase CXL13_01765 ENOG4105WCN acetyltransferase CXL13_01770 ENOG4105D9R oxidoreductase CXL13_01775 ENOG4105C2I pirin domain protein CXL13_01780 ENOG4105DIQ Transcriptional regulator CXL13_01785 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family CXL13_01790 ENOG4105C6Z Gluconate CXL13_01800 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) CXL13_01805 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) CXL13_01825 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) CXL13_01830 ENOG4107HP6 Transcriptional regulator CXL13_01835 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) CXL13_01840 ENOG4105C01 Dihydroxy-acid dehydratase CXL13_01850 ENOG4105DCT glycerol dehydrogenase CXL13_01865 ENOG4105C6V Glycerol-3-phosphate dehydrogenase CXL13_01880 ENOG4105E98 transcriptional regulator DeoR family CXL13_01885 ENOG4105CYB regulatoR CXL13_01895 ENOG4105E0Y RtcB Protein CXL13_01915 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) CXL13_01920 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) CXL13_01925 ENOG4105C6Z Gluconate CXL13_01935 ENOG4105MJ2 Competence protein CXL13_01945 ENOG4105DNE Transposase CXL13_01960 ENOG4105XFK Ferrous iron transport protein A CXL13_01970 ENOG4105BZM domain protein CXL13_01975 ENOG4108RRZ Transcription elongation factor GreB CXL13_01980 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CXL13_01985 ENOG4105E0F Histidine kinase CXL13_01995 ENOG4108MAJ Membrane CXL13_02005 ENOG4105VEJ Heat shock protein CXL13_02010 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 CXL13_02015 ENOG4105DQY intracellular growth attenuator CXL13_02020 ENOG4107RK2 ADP-ribose diphosphatase NudE CXL13_02025 ENOG4108JQC penicillin-binding protein 1A CXL13_02030 ENOG4108U1Q Pilus assembly protein CXL13_02035 ENOG41065NF Fimbrial assembly family protein CXL13_02040 ENOG4105XPX DNA utilization protein HofO CXL13_02045 ENOG4105ITY Required for the use of extracellular DNA as a nutrient CXL13_02050 ENOG4105E4G Type IV pilus CXL13_02070 ENOG4105EGB membrane protein DamX CXL13_02075 ENOG4105DFE Dna adenine methylase CXL13_02080 ENOG4105DJV ribulose-phosphate 3-epimerase CXL13_02090 ENOG4105C31 Tryptophanyl-tRNA synthetase CXL13_02095 ENOG4105VYH CXL13_02110 ENOG4107V9H nitrite transporter CXL13_02115 ENOG4105WZK nitrite reductase NADPH small subunit CXL13_02120 ENOG4107QZF nitrite reductase NADPH large subunit CXL13_02130 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) CXL13_02135 ENOG4106195 uncharacterized protein yhfG CXL13_02140 ENOG4105MZU cell filamentation protein CXL13_02145 ENOG4105DDQ anthranilate synthase CXL13_02150 ENOG4105C8Y Acetylornithine aminotransferase CXL13_02155 ENOG410613R integral membrane protein, YccS YhfK family CXL13_02165 ENOG4108UKZ OsmC family CXL13_02170 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) CXL13_02180 ENOG4105DNZ Alpha Beta Hydrolase CXL13_02185 ENOG4105N0V mono-oxygenase ydhR CXL13_02190 ENOG4108K70 Transcriptional regulator CXL13_02195 ENOG4105C5H ABC transporter CXL13_02210 ENOG4105VKU nucleicacid-binding protein CXL13_02215 ENOG4108YZY peptidylprolyl cis-trans isomerase CXL13_02230 ENOG4108V1T peptidylprolyl cis-trans isomerase CXL13_02235 ENOG4105WWK YheO domain protein CXL13_02250 ENOG4105YKK Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) CXL13_02270 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) CXL13_02285 ENOG4105W53 bacterioferritin-associated ferredoxin CXL13_02290 ENOG4108UQY Iron-storage protein CXL13_02295 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) CXL13_02315 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) CXL13_02330 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) CXL13_02335 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) CXL13_02340 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) CXL13_02350 ENOG41083MP 50s ribosomal protein l29 CXL13_02360 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) CXL13_02380 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) CXL13_02390 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) CXL13_02395 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) CXL13_02400 ENOG4105VPB 50S ribosomal protein L30 CXL13_02405 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) CXL13_02410 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) CXL13_02415 ENOG41067V7 50S ribosomal protein L36 CXL13_02435 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) CXL13_02445 ENOG4105VTS DnaJ-like, subfamily C CXL13_02450 ENOG4105W1Y Transcriptional regulator CXL13_02455 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system CXL13_02465 ENOG4105C1A potassium transporter peripheral membrane CXL13_02485 ENOG4105C79 DNA protecting protein DprA CXL13_02495 ENOG4108WI1 Dna topoisomerase CXL13_02510 ENOG4105SG3 Protein of unknown function (DUF1488) CXL13_02515 ENOG4108Z0R Transferase CXL13_02555 ENOG4105XCM membrane LIPOPROTEIN CXL13_02560 ENOG4105BZS acriflavin resistance protein CXL13_02565 ENOG4105C1P efflux transporter, rnd family, mfp subunit CXL13_02570 ENOG4108XG4 DNA-binding transcriptional regulator CXL13_02575 ENOG4105BZU Histidine kinase CXL13_02580 ENOG41061ME transport protein CXL13_02585 ENOG4105CEC DNA methylase N-4 N-6 CXL13_02590 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) CXL13_02595 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) CXL13_02610 ENOG4108IA2 Sodium pantothenate symporter CXL13_02615 ENOG4105RG0 Membrane CXL13_02620 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase CXL13_02625 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein CXL13_02640 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family CXL13_02645 ENOG41062P1 Diguanylate cyclase phosphodiesterase CXL13_02660 ENOG4105DFF Rod shape-determining protein mreb CXL13_02665 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) CXL13_02670 ENOG4105VQ7 Rod shape-determining protein MreD CXL13_02680 ENOG4105C03 ribonuclease CXL13_02685 ENOG4105QD6 exported protein CXL13_02690 ENOG4105D1U peptidase U62 modulator of DNA gyrase CXL13_02695 ENOG4105CR8 Transcriptional regulator CXL13_02700 ENOG4105ZQC membrane protein AaeX CXL13_02715 ENOG4105UNR (Barnase) inhibitor CXL13_02720 ENOG4105RID UPF0379 protein yhcN CXL13_02725 ENOG4105RID UPF0379 protein yhcN CXL13_02740 ENOG4105FDP GntR family transcriptional regulator CXL13_02750 ENOG4105C8P )-transporter CXL13_02755 ENOG4106DSS Tartrate dehydratase subunit alpha CXL13_02760 ENOG4107GFK fumarate CXL13_02770 ENOG4107QSA Oxaloacetate decarboxylase CXL13_02775 ENOG4105D9Q decarboxylase (Beta subunit) CXL13_02790 ENOG4105C0H protease CXL13_02795 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III CXL13_02800 ENOG4105D6Z AFG1 family ATPase CXL13_02815 ENOG4107MKT Stringent starvation protein a CXL13_02820 ENOG4105KB2 stringent starvation protein b CXL13_02850 ENOG4108R66 Conserved Protein CXL13_02855 ENOG4105DZC cytosine deaminase CXL13_02860 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin CXL13_02865 ENOG4105DFS Conserved Protein CXL13_02870 ENOG4105BZ8 glutamate synthase CXL13_02875 ENOG4105CBC glutamate synthase CXL13_02885 ENOG4105N5T Radical SAM Protein CXL13_02890 ENOG4105BZU Histidine kinase CXL13_02895 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain CXL13_02905 ENOG4108NIH transferase activity, transferring phosphorus-containing groups CXL13_02915 ENOG41080Z8 PHOSPHOCARRIER protein CXL13_02925 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN CXL13_02930 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA CXL13_02935 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CXL13_02940 ENOG4108IUZ ABC transporter CXL13_02945 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA CXL13_02950 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) CXL13_02955 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase CXL13_02960 ENOG4105C2X Arabinose 5-phosphate isomerase CXL13_02965 ENOG4105FEU K -dependent Na -Ca exchanger CXL13_02970 ENOG4105DHJ ABC, transporter CXL13_02975 ENOG4105CY3 ABC transporter, permease CXL13_02980 ENOG4107PE3 Mammalian cell entry related domain protein CXL13_02985 ENOG4105E3I toluene tolerance CXL13_02990 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane CXL13_02995 ENOG4105VFK BolA family CXL13_03005 ENOG4105HVQ Regulatory factor of maltose metabolism CXL13_03010 ENOG4105EAH synthase CXL13_03025 ENOG4105QYV Membrane CXL13_03035 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase CXL13_03040 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) CXL13_03045 ENOG4105HBR Rna-binding protein CXL13_03050 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) CXL13_03060 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) CXL13_03065 ENOG4105EEI dihydropteroate synthase CXL13_03105 ENOG4105CHV Transcription elongation factor NusA CXL13_03140 ENOG4105C1J atp-dependent rna helicase CXL13_03145 ENOG4105CIC tryptophan-specific transport protein CXL13_03150 ENOG4105DEN Luciferase family CXL13_03155 ENOG4106RZ4 Peptidase U32 CXL13_03160 ENOG4105CFP Peptidase U32 CXL13_03165 ENOG4105XPQ lipid carrier protein CXL13_03170 ENOG4108YYD acetyltransferase CXL13_03185 ENOG4107R7Y intracellular protease Pfpi family CXL13_03190 ENOG4105K4T epimerase CXL13_03195 ENOG4105W4M Transport-associated protein CXL13_03210 ENOG4105E1C Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity) CXL13_03215 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) CXL13_03225 ENOG4107WTH Galactitol-1-phosphate dehydrogenase CXL13_03230 ENOG4105DT3 PTS system, galactitol-specific IIc component CXL13_03235 ENOG41090UW PTS System CXL13_03240 ENOG41082GB PTS system galactitol-specific transporter subunit IIA CXL13_03255 ENOG4105CTX dehydratase CXL13_03265 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase CXL13_03270 ENOG4105BZW Glycerate kinase CXL13_03295 ENOG410811B TRANSCRIPTIONal CXL13_03300 ENOG4105C7B Threonine dehydratase CXL13_03315 ENOG4105C6N Formate acetyltransferase CXL13_03320 ENOG4105EJQ L-serine dehydratase CXL13_03325 ENOG4105C44 Serine transporter CXL13_03335 ENOG4106D80 Uncharacterized protein YhaL CXL13_03340 ENOG4108CNN domain protein CXL13_03345 ENOG4105CWB LysR family transcriptional Regulator CXL13_03350 ENOG4105KAF membrAne CXL13_03355 ENOG4105CHF Glutathione S-transferase CXL13_03360 ENOG4108VBZ doxx family CXL13_03365 ENOG4105YJD CXL13_03370 ENOG41090KG Inner membrane protein YqjE CXL13_03375 ENOG4105NE1 Conserved Protein CXL13_03380 ENOG4105WAY exported protein CXL13_03390 ENOG4106W5V Membrane CXL13_03405 ENOG4105DU1 integral membrane protein, terc CXL13_03410 ENOG4105EE0 oxidoreductase CXL13_03415 ENOG4108UB4 uncharacterized protein ygjQ CXL13_03420 ENOG4108VKG metal-dependent hydrolase CXL13_03430 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase CXL13_03445 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor CXL13_03450 ENOG4105C8Q Methyl-accepting chemotaxis CXL13_03455 ENOG4105NTW Transcriptional regulator CXL13_03460 ENOG4105Q26 Siderophore-interacting protein CXL13_03465 ENOG4108KU3 Integrase CXL13_03505 ENOG4105KSC Transcriptional regulator, TraR DksA family CXL13_03510 ENOG4105UMD exodeoxyribonuclease X CXL13_03515 ENOG4105DFE Dna adenine methylase CXL13_03550 ENOG4105ED4 portal protein CXL13_03640 ENOG4105UZW Tail fiber assembly protein CXL13_03695 ENOG4105ZTC transcriptional activator, Ogr delta CXL13_03710 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CXL13_03715 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) CXL13_03720 ENOG4105VCC 30S ribosomal protein S21 CXL13_03740 ENOG4107ZVW dihydroneopterin aldolase CXL13_03755 ENOG4106MWK domain protein CXL13_03765 ENOG4105I7R Adenylate cyclase CXL13_03785 ENOG4107S78 Band 7 protein CXL13_03790 ENOG4105PV3 Inner membrane protein yqiJ CXL13_03800 ENOG4105W0Z cytoplasmic protein CXL13_03820 ENOG4108MR7 Arylsulfotransferase CXL13_03835 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b CXL13_03840 ENOG4106032 Glutathionylspermidine synthase CXL13_03860 ENOG41087AY ADP-Ribose pyrophosphatase CXL13_03865 ENOG4108SX3 cytoplasmic protein CXL13_03870 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) CXL13_03875 ENOG4105IPS esterase CXL13_03880 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CXL13_03885 ENOG4105VRH Antibiotic biosynthesis monooxygenase CXL13_03890 ENOG4105NF4 modulator of drug activity CXL13_03895 ENOG4105DHQ Histidine kinase CXL13_03900 ENOG4105XJC Two component transcriptional regulator (Winged helix family CXL13_03905 ENOG4105H4F exported protein CXL13_03910 ENOG4105F4I Transcriptional regulator CXL13_03915 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CXL13_03920 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase CXL13_03925 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) CXL13_03930 ENOG4105CG6 trap dicarboxylate transporter dctm subunit CXL13_03940 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit CXL13_03945 ENOG4105CCT upf0313 protein CXL13_03960 ENOG4107QPK )-transporter CXL13_03965 ENOG4105CV8 reductase CXL13_03970 ENOG4108I6A alcohol dehydrogenase CXL13_03975 ENOG4105CF7 AraC family transcriptional regulator CXL13_03980 ENOG4108K81 inner membrane protein YghB CXL13_03985 ENOG4105C28 cystathionine CXL13_03995 ENOG4105CWK Biopolymer transport protein, ExbB CXL13_04000 ENOG4108ZZF transport protein (ExbD) CXL13_04005 ENOG4105CYX Short-chain dehydrogenase reductase Sdr CXL13_04030 ENOG4105C8Q Methyl-accepting chemotaxis CXL13_04035 ENOG410900S Protein of unknown function (DUF2623) CXL13_04045 ENOG4105E3S small subunit CXL13_04050 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein CXL13_04055 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit CXL13_04060 ENOG4105DPX Hydrogenase, large subunit CXL13_04065 ENOG4108USZ hydrogenase CXL13_04070 ENOG4108WGS hydrogenase 2-specific chaperone CXL13_04075 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) CXL13_04080 ENOG41082MF Hydrogenase assembly chaperone hypC hupF CXL13_04085 ENOG4105S10 periplasmic binding protein CXL13_04090 ENOG4108VJC ABC transporter, periplasmic molybdate-binding protein CXL13_04095 ENOG4105CYM Glutathione S-transferase CXL13_04100 ENOG4106032 Glutathionylspermidine synthase CXL13_04115 ENOG4105DEI Mannitol dehydrogenase CXL13_04125 ENOG4105DPW Major facilitator superfamily MFS_1 CXL13_04155 ENOG4105C26 Dehydrogenase CXL13_04160 ENOG4105CJP fad dependent oxidoreductase CXL13_04170 ENOG4105CUB amino acid CXL13_04180 ENOG4108UAJ Transcriptional regulator CXL13_04265 ENOG4108UQV Membrane CXL13_04275 ENOG4105CXN decarboxylase CXL13_04280 ENOG4105EAA nucleoside CXL13_04295 ENOG4105CEN a g-specific adenine glycosylase CXL13_04310 ENOG41090ED Protein with unknown function (DUF469) CXL13_04315 ENOG4105K33 Periplasmic Protein CXL13_04320 ENOG4105HDK L-asparaginase CXL13_04325 ENOG4106MH3 alpha helix chain CXL13_04330 ENOG4105CSA Coproporphyrinogen iii oxidase CXL13_04345 ENOG4108VIA integral membrane protein CXL13_04350 ENOG4105DFA alanine racemase domain protein CXL13_04355 ENOG4105CZX twitching motility protein CXL13_04375 ENOG4105D7Z glutathione synthase CXL13_04380 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) CXL13_04385 ENOG4105RWS endonuclease I CXL13_04395 ENOG4107QNK )-transporter CXL13_04420 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) CXL13_04430 ENOG4107YCY Transcriptional regulator CXL13_04440 ENOG4105DEI Mannitol dehydrogenase CXL13_04445 ENOG4105CPQ Dehydrogenase CXL13_04450 ENOG4105DG4 malate L-lactate dehydrogenase CXL13_04455 ENOG4108R66 Conserved Protein CXL13_04460 ENOG4108MXF Alpha Beta Hydrolase CXL13_04475 ENOG4108K0D peptidase, M48 CXL13_04480 ENOG4105CV1 Transketolase (EC 2.2.1.1) CXL13_04485 ENOG4108JJB ABC transporter CXL13_04490 ENOG4108JJB ABC transporter CXL13_04525 ENOG4105D2N Aldolase CXL13_04530 ENOG4105D64 Mechanosensitive ion channel CXL13_04540 ENOG4105MPN Membrane CXL13_04560 ENOG4108JQ1 Dehydrogenase CXL13_04565 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase CXL13_04590 ENOG4107RAQ aminopeptidase CXL13_04595 ENOG4105D0A hydroxylase CXL13_04600 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family CXL13_04630 ENOG4105CS2 ec 3.2.1.21 CXL13_04640 ENOG4108UT2 hemolysin iii CXL13_04665 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB CXL13_04670 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) CXL13_04675 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CXL13_04680 ENOG4105T95 Thiol disulfide interChange protein CXL13_04685 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) CXL13_04695 ENOG4105CRK lysyL-tRNA synthetase CXL13_04710 ENOG4108K5P (LipO)protein CXL13_04720 ENOG4105DFP Integrase CXL13_04845 ENOG4108T1M outer membrane protein x CXL13_04865 ENOG4106P2F Pfam:Pili_assembly_C CXL13_04895 ENOG4108MHD transport protein CXL13_04905 ENOG4105C5Q Transcriptional regulator CXL13_04910 ENOG4105CHU acetyl-coa acetyltransferase CXL13_04925 ENOG4105CHR reductase CXL13_04930 ENOG4107QNK )-transporter CXL13_04940 ENOG4105RQF LysR family Transcriptional regulator CXL13_04945 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) CXL13_04950 ENOG4105DDV Transcriptional regulator (LacI family CXL13_04980 ENOG4105CPC Aldo Keto reductase CXL13_04985 ENOG4105SUV lipoprotein YgdR CXL13_04990 ENOG4105EE5 Membrane protein terC CXL13_05005 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase CXL13_05025 ENOG4105IPU prepilin peptidase dependent protein A CXL13_05030 ENOG4105JCS prepilin peptidase dependent protein CXL13_05035 ENOG4105RVB Prepilin peptidase dependent protein c CXL13_05040 ENOG4105DSY exodeoxyribonuclease V, gamma CXL13_05045 ENOG4107QXK peptidase CXL13_05050 ENOG4107QKA exodeoxyribonuclease V beta CXL13_05055 ENOG4107QYX exodeoxyribonuclease v alpha CXL13_05060 ENOG4108EKC n-acetylglutamate synthase CXL13_05065 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase CXL13_05080 ENOG4105CA3 membrane-bound lytic murein transglycosylase CXL13_05085 ENOG4105CUZ uba thif-type nad fad binding protein CXL13_05090 ENOG4105FR1 rard protein CXL13_05095 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) CXL13_05100 ENOG4105C9B Cysteine desulfurase CXL13_05105 ENOG4105M5B (LipO)protein CXL13_05110 ENOG4105ETT transcriptional Regulator, LysR family CXL13_05115 ENOG4105M08 Membrane CXL13_05125 ENOG4107EDW L-fucose operon activator CXL13_05135 ENOG4105CMG Carbohydrate kinase CXL13_05145 ENOG4105EDR glucose galactose transporter CXL13_05150 ENOG4107W7X Aldolase CXL13_05155 ENOG4105C0A alcohol dehydrogenase CXL13_05170 ENOG4105EJQ L-serine dehydratase CXL13_05175 ENOG4105C44 Serine transporter CXL13_05180 ENOG4105EWT decarboxylase family CXL13_05200 ENOG4105WP7 tRNA pseudouridine synthase C CXL13_05205 ENOG4105DR9 pseudouridine synthase CXL13_05210 ENOG4105QDK Flavodoxin CXL13_05220 ENOG4105DJB Major Facilitator Superfamily CXL13_05225 ENOG4105EQX glucarate dehydratase CXL13_05230 ENOG4105EQX glucarate dehydratase CXL13_05235 ENOG4105BZW Glycerate kinase CXL13_05240 ENOG4105BZU Histidine kinase CXL13_05245 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) CXL13_05250 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) CXL13_05275 ENOG4105NEV Fimbrial CXL13_05280 ENOG4108FZ9 Chaperone CXL13_05285 ENOG4106PG1 outer membrane usher protein CXL13_05295 ENOG4105DXN mazG family CXL13_05310 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) CXL13_05315 ENOG4108H5C Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) CXL13_05320 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase CXL13_05330 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) CXL13_05340 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) CXL13_05350 ENOG4105DTT CRISPR-associated helicase, cas3 CXL13_05365 ENOG41060M0 Crispr-associated protein, cse4 family CXL13_05370 ENOG4108VWQ crispr-associated protein CXL13_05380 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) CXL13_05385 ENOG4105PWE CRISPR-associated protein cas2 CXL13_05390 ENOG4108MXK alkaline phosphatase isozyme conversion CXL13_05410 ENOG4105N0Z inner membrane protein ygbE CXL13_05445 ENOG4108K5P (LipO)protein CXL13_05455 ENOG4105KZM cytoplasmic protein CXL13_05460 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) CXL13_05465 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase CXL13_05475 ENOG4105MVE transcriptional regulator CXL13_05485 ENOG4105G63 Type III effector Hrp-dependent CXL13_05495 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) CXL13_05500 ENOG4105EXW epimerase dehydratase CXL13_05505 ENOG4105C6Z Gluconate CXL13_05510 ENOG4105JQN Transcriptional regulator CXL13_05550 ENOG4105MEW serine threonine protein phosphatase CXL13_05595 ENOG41090HZ type iii secretion CXL13_05600 ENOG4105K44 type iii secretion CXL13_05605 ENOG4108N8R Invasion protein CXL13_05610 ENOG4108HR8 type iii secretion CXL13_05615 ENOG4105REY Chaperone specialized in the storage of effectors within the bacterial cytoplasm, maintaining them in a secretion-competent state, and allowing their immediate delivery to target cells upon contact of the bacterium with the host cells. Has been shown to chaperone CXL13_05620 ENOG4108JIR Flagellum-specific ATP synthase CXL13_05625 ENOG41077MC Secretory protein (Associated with virulence) CXL13_05630 ENOG41078G4 surface presentation of CXL13_05635 ENOG4105T85 surface presentation of antigens protein CXL13_05640 ENOG41075IY surface presentation of antigens protein SpaP CXL13_05650 ENOG4108TN6 type iii secretion CXL13_05655 ENOG4108M6W surface presentation of antigens protein SpaS CXL13_05665 ENOG4106H1J Required for entry into the host cell through presentation or delivery of SipC at the host cell plasma membrane. Along with SipC, is necessary for the transfer of other effector proteins into the host cell. Induces macrophage apoptosis either by binding and activating the proapoptotic enzyme caspase-1 (caspase-1 dependent), resulting in the release of interleukin-1 beta active form, or by disrupting mitochondria and inducing autophagy (caspase-1 independent). The former is dependent of its membrane-fusion activity. The SipBC complex, in association with its chaperone SicA, is regulated by binding of InvE CXL13_05675 ENOG4105IBT Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of SipA, SipB, and SipC CXL13_05685 ENOG41079WB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) CXL13_05700 ENOG410641W Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities. After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE. This function is independent of its tyrosine phosphatase activity, which remains unclear CXL13_05710 ENOG4108YAB Invasion protein CXL13_05720 ENOG4108RC9 Type III secretion system protein CXL13_05725 ENOG4105Y7Q type iii secretion CXL13_05730 ENOG4106BTR CXL13_05735 ENOG4108RBT type iii secretion CXL13_05775 ENOG4105CC5 ABC transporter CXL13_05780 ENOG4105CC5 ABC transporter CXL13_05785 ENOG4105DIK (ABC) transporter CXL13_05795 ENOG4105VXR cytoplasmic protein CXL13_05805 ENOG4105C45 hydrogenase expression formation protein (HypE) CXL13_05810 ENOG4105CQS hydrogenase expression formation protein HypD CXL13_05815 ENOG41083WG hydrogenase assembly chaperone CXL13_05820 ENOG4107RSS Hydrogenase accessory protein HypB CXL13_05825 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) CXL13_05835 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA CXL13_05840 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) CXL13_05845 ENOG4107R30 NADH dehydrogenase CXL13_05850 ENOG4107TDF Formate hydrogenlyase subunit 4 CXL13_05855 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) CXL13_05860 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit CXL13_05865 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit CXL13_05870 ENOG4105I6X formate hydrogenlyase maturation CXL13_05875 ENOG4108MG9 hydrogenase 3 maturation protease CXL13_05885 ENOG4108RC0 Electron transport protein CXL13_05890 ENOG4105C8H hydrogenase maturation protein Hypf CXL13_05910 ENOG4105C2X Arabinose 5-phosphate isomerase CXL13_05915 ENOG410804X Transcriptional regulator CXL13_05920 ENOG4105J92 DNA-binding transcriptional activator GutM CXL13_05925 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase CXL13_05930 ENOG4105VI0 Pts system, glucitol sorbitol-specific CXL13_05935 ENOG4105DZY Pts system, glucitol sorbitol-specific CXL13_05940 ENOG410787A Pts system, glucitol sorbitol-specific CXL13_05945 ENOG4105CVE Lytic murein transglycosylase CXL13_05955 ENOG4107TH8 cina domain protein CXL13_05975 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) CXL13_05980 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) CXL13_06015 ENOG4107VXZ Hydrolase CXL13_06020 ENOG4105W39 Membrane CXL13_06040 ENOG4105C0R drug resistance transporter emrb qaca subfamily CXL13_06045 ENOG4105CW7 secretion protein, HlyD family CXL13_06050 ENOG4105NTK Transcriptional repressor Mpra CXL13_06060 ENOG4105GIJ Glycine betaine CXL13_06065 ENOG4108HQS Glycine betaine CXL13_06070 ENOG4108IJ7 Glycine betaine CXL13_06080 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CXL13_06085 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CXL13_06095 ENOG4105WAZ (Glutaredoxin-like protein) NrdH CXL13_06105 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) CXL13_06115 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) CXL13_06120 ENOG4108WMJ Protein of unknown function (DUF2002) CXL13_06125 ENOG4108RNS Exports L-alanine (By similarity) CXL13_06135 ENOG4108X73 DNA- binding protein CXL13_06145 ENOG4108V62 Rhodanese domain protein CXL13_06150 ENOG41080HT Transcriptional regulator, arsr family CXL13_06155 ENOG4105VPI YqaE family transport protein CXL13_06165 ENOG4109066 lysm domain bon superfamily protein CXL13_06170 ENOG4108PVQ transcriptional regulator CXL13_06175 ENOG4105C85 amino acid CXL13_06180 ENOG4108JPW Aminotransferase CXL13_06185 ENOG4105C26 Dehydrogenase CXL13_06190 ENOG4105D5U fad dependent oxidoreductase CXL13_06220 ENOG4105DHQ Histidine kinase CXL13_06240 ENOG4108MJ5 VirK protein CXL13_06255 ENOG4107RNH Outer membrane receptor FepA CXL13_06260 ENOG4105NIV Esterase CXL13_06290 ENOG4105XDF Protein of unknown function (DUF1272) CXL13_06300 ENOG4105F9F transposase CXL13_06340 ENOG4105BZ1 (ABC) transporter CXL13_06360 ENOG4108Z1B Cyclase dehydrase CXL13_06370 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) CXL13_06375 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) CXL13_06400 ENOG4108JU6 CBS domain protein CXL13_06405 ENOG4106KVJ cytochrome C assembly protein CXL13_06415 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY CXL13_06440 ENOG4108KHX Diguanylate cyclase CXL13_06445 ENOG4108WS1 CXL13_06450 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) CXL13_06455 ENOG4105EHE chorismate mutase- prephenate dehydrogenase CXL13_06465 ENOG4105CQC Prephenate dehydratase CXL13_06475 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA CXL13_06480 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane CXL13_06485 ENOG4105C34 Pseudouridine synthase CXL13_06490 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase CXL13_06495 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CXL13_06530 ENOG4105CSH Transporter CXL13_06535 ENOG4105T42 (LipO)protein CXL13_06540 ENOG4105JIM Phosphatidylserine synthase CXL13_06545 ENOG4105CD5 CoA-binding domain protein CXL13_06550 ENOG4106IUH DTW domain containing protein CXL13_06555 ENOG4105K63 Thioredoxin CXL13_06560 ENOG4105EIB trna rrna methyltransferase CXL13_06580 ENOG41090KR LysR family transcriptional Regulator CXL13_06585 ENOG4105C1J atp-dependent rna helicase CXL13_06595 ENOG4108IYU L-aspartate oxidase CXL13_06620 ENOG4105WMJ Positive regulator of sigma E, RseC MucC CXL13_06635 ENOG4105C3F Signal peptidase i CXL13_06670 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding CXL13_06675 ENOG4105DND Transcriptional regulator CXL13_06680 ENOG4105FCD Major Facilitator CXL13_06685 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) CXL13_06690 ENOG4106G6Q Transcriptional regulator CXL13_06705 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB CXL13_06710 ENOG4108Z6B deaminase CXL13_06715 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) CXL13_06725 ENOG4108ETH Formylglycinamide ribotide synthetase CXL13_06730 ENOG4107WP9 Histidine kinase CXL13_06735 ENOG4108SKK alpha helix protein CXL13_06740 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CXL13_06745 ENOG4108YZA Nitrogen regulatory protein pii CXL13_06750 ENOG4105DUX Transporter CXL13_06755 ENOG4105CXN decarboxylase CXL13_06760 ENOG4105D5Q Arginine ornithine antiporter CXL13_06765 ENOG4108M3R transcriptional activator CadC CXL13_06770 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) CXL13_06775 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) CXL13_06780 ENOG4105D8G Major Facilitator superfamily CXL13_06785 ENOG4108MN2 Stationary phase inducible protein CsiE CXL13_06795 ENOG4105D7X high-affinity nickel-transporter CXL13_06800 ENOG410810Y Sulfite reductase CXL13_06805 ENOG4107SHJ sulfite reductase subunit b CXL13_06810 ENOG4105D5B Sulfite reductase, subunit A CXL13_06815 ENOG4107XM9 (LipO)protein CXL13_06820 ENOG4105ECY inositol monophosphatase CXL13_06840 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins CXL13_06860 ENOG4108ZIT Ferredoxin, 2FE-2S CXL13_06865 ENOG4105WVQ Fe-S assembly protein IscX CXL13_06880 ENOG4105YYA enhanced serine sensitivity protein SseB CXL13_06900 ENOG4105KHC sulfurtransferase CXL13_06905 ENOG4105DN3 alpha-2-macroglobulin domain protein CXL13_06910 ENOG4108JQB penicillin-binding protein 1C CXL13_06915 ENOG4107QY8 reductase CXL13_06920 ENOG4105QAX Iron-sulfur CXL13_06965 ENOG4105N21 Membrane CXL13_06970 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) CXL13_06980 ENOG4105VPD cellular component movement CXL13_07015 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) CXL13_07040 ENOG41062G3 Protein of unknown function (DUF2633) CXL13_07050 ENOG4105BZU Histidine kinase CXL13_07055 ENOG4105C9X ppx gppa phosphatase CXL13_07060 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) CXL13_07065 ENOG4108V3E phosphoribosylglycinamide formyltransferase CXL13_07080 ENOG4105C2W permease CXL13_07090 ENOG4105K89 arsenate reductase CXL13_07095 ENOG4105ERG peptidase m48, ste24p CXL13_07100 ENOG4105C02 permease CXL13_07105 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR CXL13_07110 ENOG4107QQ0 gntp family CXL13_07115 ENOG4105BZW Glycerate kinase CXL13_07120 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen CXL13_07125 ENOG4105RH4 Glycine cleavage system transcriptional repressor CXL13_07135 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) CXL13_07145 ENOG4105CGZ zinc metallopeptidase CXL13_07150 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) CXL13_07165 ENOG4105KUZ arsenate reductase CXL13_07175 ENOG4105BZS acriflavin resistance protein CXL13_07180 ENOG4105BZU Histidine kinase CXL13_07185 ENOG4105BZ8 glutamate synthase CXL13_07205 ENOG4108PVD exported protein CXL13_07215 ENOG4105CV1 Transketolase (EC 2.2.1.1) CXL13_07230 ENOG4105C6K Malic enzyme CXL13_07235 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place CXL13_07240 ENOG4106S4J ethanolamine utilization protein EutP CXL13_07245 ENOG4105NDK ethanolamine utilization protein CXL13_07250 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase CXL13_07255 ENOG4108IJ2 phosphate acetyltransferase CXL13_07260 ENOG4105KNY Microcompartments protein CXL13_07265 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml CXL13_07270 ENOG4108EKI Dehydrogenase CXL13_07275 ENOG4107RWI ethanolamine utilization protein eutJ CXL13_07280 ENOG4105C0A alcohol dehydrogenase CXL13_07285 ENOG4105ENY Ethanolamine utilization protein eutH CXL13_07290 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase CXL13_07295 ENOG4105CPD ethanolamine ammonia-lyase CXL13_07305 ENOG4106D67 ethanolamine utilization protein CXL13_07310 ENOG4108X49 Ethanolamine utilization protein EutK CXL13_07315 ENOG4108K3Z AraC family transcriptional regulator CXL13_07320 ENOG4107H8F CXL13_07335 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase CXL13_07345 ENOG4105QZU Inner membrane protein YfeZ CXL13_07350 ENOG4105E7K (LipO)protein CXL13_07355 ENOG4105EZR dyp-type peroxidase family protein CXL13_07360 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr CXL13_07365 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein CXL13_07370 ENOG4108I5D sulfate abc transporter CXL13_07375 ENOG4105ECW sulfate abc transporter CXL13_07380 ENOG4108IJ6 ABC transporter CXL13_07385 ENOG4105C6T cysteine synthase CXL13_07405 ENOG4105M0Y CXL13_07410 ENOG41089BK Glutamine amido-transferase CXL13_07415 ENOG4105CSW GntR family transcriptional regulator CXL13_07430 ENOG4105C5Y PTS System CXL13_07440 ENOG4105KZ7 phosphocarrier protein hpr CXL13_07445 ENOG4105C6T cysteine synthase CXL13_07465 ENOG4105VRT cytoplasmic protein CXL13_07470 ENOG4105DHU Bile acid CXL13_07475 ENOG4108M0I Transcriptional regulator CXL13_07480 ENOG4108NFH Sugar hydrolase CXL13_07485 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) CXL13_07490 ENOG4105EAA nucleoside CXL13_07500 ENOG4105CN8 Transcriptional regulator CXL13_07530 ENOG4105GXM Putative transcription regulator (DUF1323) CXL13_07535 ENOG4105HZG regulatoR CXL13_07555 ENOG4108KMM Diguanylate cyclase CXL13_07560 ENOG4105D9N nucleoside CXL13_07570 ENOG4109076 Conserved Protein CXL13_07575 ENOG4105CPC Aldo Keto reductase CXL13_07585 ENOG4107RA9 decarboxylase CXL13_07605 ENOG4105CHM Aminotransferase CXL13_07615 ENOG4105D1S lipid A biosynthesis CXL13_07620 ENOG4105W9M Membrane CXL13_07625 ENOG4105CXY transporter CXL13_07635 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC CXL13_07645 ENOG4107TXD phosphoglycerate transport system transcriptional regulatory protein pgta CXL13_07650 ENOG4108NC2 Outer membrane protease CXL13_07660 ENOG41065VV Transcription inhibitory protein for the torCAD operon. Also acts as an excisionase and plays an essential role in the defective prophage CPS53 excision CXL13_07720 ENOG4108PNI recT protein CXL13_07830 ENOG4105RWQ Protein of unknown function (DUF1364) CXL13_07990 ENOG4105CKK Glycosyl transferase, family 2 CXL13_07995 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) CXL13_08000 ENOG4105DFP Integrase CXL13_08010 ENOG4105S64 Formate nitrite transporter CXL13_08015 ENOG410903C (LipO)protein CXL13_08020 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation CXL13_08030 ENOG4105KZW UPF0381 protein CXL13_08045 ENOG4108BY2 phosphohistidine phosphatase CXL13_08055 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) CXL13_08070 ENOG4105EJ9 Membrane CXL13_08075 ENOG4108BPE -transporting atpase CXL13_08080 ENOG4105MH2 YfcL protein CXL13_08085 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) CXL13_08090 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CXL13_08110 ENOG4105R8V Transcriptional regulator CXL13_08125 ENOG4106WZ1 flagella biosynthesis regulator CXL13_08135 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) CXL13_08145 ENOG4105DQR SNARE associated Golgi CXL13_08155 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase CXL13_08160 ENOG4108S3P Sporulation domain protein CXL13_08165 ENOG4105E96 Colicin v production protein CXL13_08170 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase CXL13_08175 ENOG4108JUB Transcriptional regulator CXL13_08185 ENOG4105E5D amino acid CXL13_08190 ENOG4106M28 alanine racemase domain protein CXL13_08200 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase CXL13_08210 ENOG4105E89 ABC transporter CXL13_08215 ENOG4105E89 ABC transporter CXL13_08220 ENOG4105DSP amino acid AbC transporter CXL13_08225 ENOG4106YG3 ABC transporter CXL13_08230 ENOG4108JEH abc transporter atp-binding protein CXL13_08235 ENOG4105ECP epimerase CXL13_08240 ENOG4105CYM Glutathione S-transferase CXL13_08245 ENOG4108SHQ Glutathione S-transferase CXL13_08250 ENOG4108RE9 Phosphodiesterase CXL13_08255 ENOG4105PTV Nudix Hydrolase CXL13_08260 ENOG4105K2J Transcriptional regulator CXL13_08270 ENOG4106ETB IIa component CXL13_08280 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC CXL13_08285 ENOG4108HHA Transketolase CXL13_08290 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) CXL13_08295 ENOG4105CSX c4-dicarboxylate anaerobic carrier CXL13_08300 ENOG4105C6K Malic enzyme CXL13_08305 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) CXL13_08320 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 CXL13_08325 ENOG4107QWE )-transporter CXL13_08335 ENOG4105CHM Aminotransferase CXL13_08345 ENOG4107NQ8 LysR family Transcriptional regulator CXL13_08370 ENOG4105GKE subunit e CXL13_08375 ENOG4107QIZ NADH dehydrogenase CXL13_08380 ENOG4107R0R NADH dehydrogenase subunit g CXL13_08395 ENOG4107UFS subunit j CXL13_08405 ENOG4105D65 subunit l CXL13_08410 ENOG4105C8S subunit m CXL13_08425 ENOG4105CP2 von willebrand factor, type a CXL13_08430 ENOG4107R88 Chemotaxis protein (CheV) CXL13_08440 ENOG4107YB6 acetyltransferase, (GNAT) family CXL13_08445 ENOG4105TNS Conserved Protein CXL13_08450 ENOG4105E4F Isochorismate synthase CXL13_08465 ENOG4108IPT Naphthoate synthase CXL13_08475 ENOG4105CEY Amp-dependent synthetase and ligase CXL13_08480 ENOG4106GZG polymyxin resistance protein B CXL13_08515 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase CXL13_08530 ENOG4108UII YfaZ family CXL13_08540 ENOG4107258 Transcriptional regulator CXL13_08550 ENOG4105CSP Major Facilitator Superfamily CXL13_08565 ENOG4105Z6G Protease that can act as an efficient and specific deubiquitinating enzyme in vitro. Does not possess desumoylating and deneddylating activities. The physiological substrate is CXL13_08575 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) CXL13_08585 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A CXL13_08590 ENOG4105CXY transporter CXL13_08595 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase CXL13_08600 ENOG4105GZI Transcriptional regulator CXL13_08605 ENOG4105CZM Major Facilitator CXL13_08610 ENOG4105XPH Ferredoxin CXL13_08615 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CXL13_08620 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CXL13_08625 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) CXL13_08630 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CXL13_08635 ENOG4105BZU Histidine kinase CXL13_08640 ENOG41068CG regulatoR CXL13_08645 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC CXL13_08655 ENOG4105FCK Membrane CXL13_08660 ENOG4105CJ2 (LipO)protein CXL13_08665 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) CXL13_08670 ENOG4105CF1 Alkylated DNA repair protein CXL13_08675 ENOG4105IBP Cyclic peptide transporter CXL13_08685 ENOG4108ZNS ferredoxin-type protein NapF CXL13_08690 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase CXL13_08700 ENOG4108BGM Quinol dehydrogenase periplasmic component CXL13_08705 ENOG4105GXZ Ferredoxin-type protein NapH CXL13_08715 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) CXL13_08720 ENOG4105CUW cytochrome C-TYPE protein CXL13_08730 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) CXL13_08735 ENOG41060IM Heme exporter protein CXL13_08740 ENOG4105X3C heme exporter protein CXL13_08745 ENOG4108ZKK Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity) CXL13_08750 ENOG4105DA4 cytochrome c-type biogenesis protein CXL13_08755 ENOG4107QX9 Thiol disulfide interChange protein CXL13_08760 ENOG4105KWW Biogenesis protein CXL13_08765 ENOG4105WH1 Two component transcriptional regulator luxr family CXL13_08790 ENOG4105E68 Sulfatase CXL13_08815 ENOG4105CFI type iii restriction protein res subunit CXL13_08820 ENOG4105I08 Pseudouridine synthase CXL13_08825 ENOG4105C2C drug resistance transporter, Bcr CflA CXL13_08835 ENOG4105HG6 CXL13_08840 ENOG4108JQ5 ABC transporter CXL13_08845 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component CXL13_08850 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component CXL13_08855 ENOG4105E43 Extracellular solute-binding protein, family 5 CXL13_08860 ENOG4105CXC rtn protein CXL13_08870 ENOG4107TT5 NLP P60 protein CXL13_08880 ENOG41076MN Phosphoesterase, PA-phosphatase related CXL13_08885 ENOG4105CKI cobalamin synthesis protein CXL13_08890 ENOG4105FUQ Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) CXL13_08895 ENOG4105KRS Proteinase inhibitor CXL13_08910 ENOG4105S8Q sugar efflux transporter CXL13_08915 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein CXL13_08920 ENOG4105DE4 1-phosphofructokinase CXL13_08925 ENOG4105DM4 PTS System CXL13_08935 ENOG4105HMI Membrane CXL13_08940 ENOG4105DUM transcriptional regulator, lysR family CXL13_08945 ENOG4108IQI permease CXL13_08955 ENOG4105D05 Receptor CXL13_08960 ENOG4105CXY transporter CXL13_08965 ENOG4105EAC phosphoserine phosphatase CXL13_08970 ENOG4105EJQ L-serine dehydratase CXL13_08995 ENOG4105DHF Membrane CXL13_09000 ENOG41060NJ transcriptional regulator CXL13_09005 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator CXL13_09010 ENOG4105C2J ABC transporter CXL13_09015 ENOG4107SDZ Galactoside transport system permease protein mglC CXL13_09020 ENOG4107SJI Dehydrogenase CXL13_09025 ENOG4105BZ8 glutamate synthase CXL13_09030 ENOG4105Y9N Membrane CXL13_09035 ENOG4107GZ4 SanA protein CXL13_09045 ENOG41067MG lrgb family CXL13_09075 ENOG4108RXX maleylacetoacetate isomerase CXL13_09080 ENOG4105MSY salicylate hydroxylase CXL13_09085 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) CXL13_09095 ENOG4105ETP RND efflux system, outer membrane lipoprotein CXL13_09100 ENOG4105H9W Short-chain dehydrogenase reductase Sdr CXL13_09105 ENOG4105KHU inner membrane protein YohD CXL13_09110 ENOG41069YE inner membrane protein yohC CXL13_09120 ENOG41061WM D-Alanyl-D-Alanine CXL13_09125 ENOG4105CXG d-lactate dehydrogenase CXL13_09130 ENOG4107QK4 glycoside hydrolase, family 3 domain protein CXL13_09135 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system CXL13_09140 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component CXL13_09145 ENOG4108IJ8 ABC transporter CXL13_09150 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component CXL13_09165 ENOG4108HRK Histidine kinase CXL13_09170 ENOG4108NEV two component transcriptional regulator, LytTR family CXL13_09175 ENOG4108W15 Protein of unknown function (DUF1456) CXL13_09185 ENOG4108YCW (LipO)protein CXL13_09195 ENOG4105D1F ATP-binding protein CXL13_09210 ENOG4108MQF Chaperone CXL13_09215 ENOG4105CW0 outer membrane usher protein CXL13_09220 ENOG410662B Type-1 fimbrial protein CXL13_09225 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly CXL13_09235 ENOG4105DWF phosphomethylpyrimidine kinase CXL13_09240 ENOG4105FDP GntR family transcriptional regulator CXL13_09245 ENOG4108TFM Kinase, PfkB family CXL13_09250 ENOG4108KD5 ADP-ribosylation crystallin J1 CXL13_09255 ENOG4105EAA nucleoside CXL13_09260 ENOG4105EIE fructose-bisphosphate aldolase CXL13_09275 ENOG41090V3 Tir chaperone protein (CesT) family CXL13_09285 ENOG4105CFP Peptidase U32 CXL13_09315 ENOG41079JQ Membrane CXL13_09335 ENOG4105CNA YD repeat protein CXL13_09340 ENOG4105NUP lyase containing HEAT-repeat CXL13_09395 ENOG4105E3W Two component transcriptional regulator (Winged helix family CXL13_09400 ENOG4105EB3 Histidine kinase CXL13_09430 ENOG4105R8A Heat shock protein CXL13_09440 ENOG4105D03 DNA-3-methyladenine glycosylase II CXL13_09445 ENOG4105BZU Histidine kinase CXL13_09460 ENOG4108GAE asmA family CXL13_09465 ENOG4105EE5 Membrane protein terC CXL13_09475 ENOG4105DAY polysaccharide export protein CXL13_09480 ENOG4105KJF protein tyrosine phosphatase CXL13_09485 ENOG4105D75 Capsular exopolysaccharide family CXL13_09490 ENOG41090RK glycosyl transferase CXL13_09495 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB CXL13_09500 ENOG4107RXY Glycosyl transferase CXL13_09505 ENOG4108NYJ Colanic acid CXL13_09510 ENOG4105ECJ Glycosyl Transferase CXL13_09515 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF CXL13_09520 ENOG4105C0K Gdp-mannose 4,6-dehydratase CXL13_09525 ENOG4105C30 Nad-dependent epimerase dehydratase CXL13_09530 ENOG4105FGF GDP-mannose mannosyl hydrolase CXL13_09535 ENOG4106CD9 glycosyl transferase group 1 CXL13_09540 ENOG4105CJT Mannose-1-phosphate guanylyltransferase CXL13_09545 ENOG4107QKV phosphomannomutase CXL13_09550 ENOG4105D3Q Sugar transferase CXL13_09555 ENOG4105PSV Polysaccharide Biosynthesis Protein CXL13_09560 ENOG4105C74 pyruvyl transferase CXL13_09565 ENOG4107T8Q Glycosyl transferase (Group 1 CXL13_09570 ENOG4105G1A colanic acid biosynthesis protein CXL13_09575 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase CXL13_09615 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) CXL13_09625 ENOG4105C6Y Udp-glucose 6-dehydrogenase CXL13_09630 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) CXL13_09635 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase CXL13_09665 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) CXL13_09680 ENOG4108535 NAD dependent epimerase/dehydratase family CXL13_09685 ENOG4105EQ1 Transcriptional regulator CXL13_09695 ENOG4105CUB amino acid CXL13_09700 ENOG4105CJB Exodeoxyribonuclease I CXL13_09720 ENOG4108J2R molybdopterin oxidoreductase CXL13_09725 ENOG4105QAX Iron-sulfur CXL13_09730 ENOG4108NWD Cytochrome CXL13_09735 ENOG4105DZ1 carboxypeptidase CXL13_09740 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) CXL13_09745 ENOG4105DR8 Membrane CXL13_09755 ENOG4105JZC GHMP kinase CXL13_09760 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) CXL13_09765 ENOG4105KTW ethanolamine utilization protein CXL13_09770 ENOG4105M3W utilization protein CXL13_09780 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) CXL13_09785 ENOG4108EKI Dehydrogenase CXL13_09790 ENOG4108EKI Dehydrogenase CXL13_09800 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml CXL13_09810 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) CXL13_09815 ENOG4105S3V Carbon dioxide concentrating mechanism protein CXL13_09820 ENOG4105KNY Microcompartments protein CXL13_09830 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit CXL13_09835 ENOG4108ZFT Dehydratase small subunit CXL13_09840 ENOG4105YCI dehydratase medium subunit CXL13_09845 ENOG4105DMB glycerol dehydratase CXL13_09850 ENOG4105EHR propanediol utilization protein pduB CXL13_09855 ENOG4105KNY Microcompartments protein CXL13_09860 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) CXL13_09865 ENOG4107XVH Transcriptional regulator CXL13_09870 ENOG4105C0Y Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) CXL13_09880 ENOG41081F0 Precorrin-8x methylmutase CXL13_09890 ENOG4108DR9 Cobalt-precorrin-6Y C(5)-methyltransferase CXL13_09895 ENOG4107XSI cobalt-precorrin-6y C15-methyltransferase CXL13_09900 ENOG4105CIA precorrin-4 C(11)-methyltransferase CXL13_09905 ENOG4108P62 biosynthesis protein (CbiG) CXL13_09910 ENOG4105E4R Precorrin-3B C17-methyltransferase CXL13_09915 ENOG4105QUC reductase CXL13_09920 ENOG4107PPM cobalt chelatase CXL13_09925 ENOG4105DVK Precorrin-2 c20-methyltransferase CXL13_09930 ENOG4105CFT Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) CXL13_09940 ENOG4108V4M Cobalt abc transporter CXL13_09945 ENOG4108JJB ABC transporter CXL13_09955 ENOG4108YZT Adenosylcobinamide kinase CXL13_09970 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein CXL13_09985 ENOG4105CXN decarboxylase CXL13_10000 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase CXL13_10015 ENOG41085FC arsR family transcriptional regulator CXL13_10020 ENOG4108UXE Protein tyrosine phosphatase CXL13_10035 ENOG4105D6J arsenicaL-resistance protein CXL13_10055 ENOG4105UQX Mate efflux family protein CXL13_10085 ENOG4105FYV Amp nucleosidase CXL13_10165 ENOG4105HVQ Regulatory factor of maltose metabolism CXL13_10225 ENOG4105KT5 UmuD protein CXL13_10230 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) CXL13_10245 ENOG4105FCK Membrane CXL13_10250 ENOG4105Y0K Inner membrane protein YedR CXL13_10255 ENOG4105EST Metal Dependent Phosphohydrolase CXL13_10260 ENOG4105DVF Cytosine-specific methyltransferase CXL13_10265 ENOG41090BB DNA mismatch endonuclease (vsr) CXL13_10270 ENOG4105FDR Membrane CXL13_10275 ENOG4105CKW Inner membrane protein yedI CXL13_10280 ENOG4105VNZ cytoplasmic protein CXL13_10295 ENOG4105YX3 cellular response to acidity CXL13_10305 ENOG4107TKS colanic acid capsular biosynthesis activation protein A CXL13_10310 ENOG4105D19 Role in flagellar biosynthesis (By similarity) CXL13_10315 ENOG4105VS8 Flagellar biosynthetic protein fliq CXL13_10320 ENOG4105CN7 Flagellar biosynthetic protein FliP CXL13_10325 ENOG4105K0P flagellar biosynthesis protein CXL13_10330 ENOG4105DD5 Flagellar motor switch protein CXL13_10335 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) CXL13_10340 ENOG4107ZI8 flagellar basal body-associated protein flil CXL13_10345 ENOG4105WF4 Flagellar hook-length control protein CXL13_10350 ENOG4105GSA Flagellar export protein flij CXL13_10355 ENOG4108JIR Flagellum-specific ATP synthase CXL13_10360 ENOG41090PJ Flagellar assembly protein CXL13_10365 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) CXL13_10370 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) CXL13_10385 ENOG4105KSU Redox protein CXL13_10390 ENOG41066VF YeeE YedE family protein CXL13_10395 ENOG4105JCU Inherit from NOG: (Lipo)protein CXL13_10400 ENOG4105E5K Alpha-amylase CXL13_10410 ENOG4105MQ3 flagellar protein FliS CXL13_10415 ENOG4105DTS flagellar hook-associated CXL13_10430 ENOG4108C80 FliB family CXL13_10435 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CXL13_10440 ENOG4108M9K flagella biosynthesis protein FliZ CXL13_10445 ENOG4105EAB amino acid AbC transporter CXL13_10455 ENOG4105E5Q amino acid AbC transporter CXL13_10460 ENOG4105CDA abc transporter atp-binding protein CXL13_10465 ENOG4105VJY transcriptional regulator CXL13_10470 ENOG4105XVG cytoplasmic protein CXL13_10480 ENOG4105WH1 Two component transcriptional regulator luxr family CXL13_10525 ENOG4106RHG Yeca family CXL13_10530 ENOG4105E0U tyrosine-specific transport protein CXL13_10535 ENOG4105VVZ metal-binding protein CXL13_10540 ENOG41090A1 ferritin CXL13_10545 ENOG4105P23 (LipO)protein CXL13_10555 ENOG4108UEC Ferritin-like protein CXL13_10565 ENOG4105CNN ABC, transporter CXL13_10570 ENOG4108K4C ec 3.1.3.12 CXL13_10580 ENOG4108VA4 Universal stress protein CXL13_10590 ENOG4105GEH Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity) CXL13_10595 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region CXL13_10600 ENOG4107RD7 Flagellar Motor Protein, MotA CXL13_10605 ENOG4105ER2 Ompa motb domain protein CXL13_10610 ENOG4105CBS Chea signal transduction histidine kinase CXL13_10615 ENOG4108V3W Chemotaxis protein, CheW CXL13_10620 ENOG4105C8Q Methyl-accepting chemotaxis CXL13_10625 ENOG4105BZU Histidine kinase CXL13_10635 ENOG4108VYJ response regulator receiver protein CXL13_10640 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) CXL13_10645 ENOG4105D00 flagellar biosynthetic protein flhB CXL13_10650 ENOG4105D7B Flagellar biosynthesis protein flha CXL13_10655 ENOG4105IRD Flagellar protein FlhE CXL13_10660 ENOG4105F5H Glycosyl Hydrolase Family 88 CXL13_10675 ENOG4106ZCM YecM protein CXL13_10700 ENOG4105WJG Glutathione CXL13_10705 ENOG41081XQ Conserved Protein CXL13_10710 ENOG4105D3W isochorismatase CXL13_10720 ENOG4108TIT dATP pyrophosphohydrolase CXL13_10735 ENOG4107S01 Repressor protein MetJ CXL13_10755 ENOG4105FAV ABC, transporter CXL13_10765 ENOG4105NXV High-affinity zinc uptake system protein CXL13_10770 ENOG4105DR5 peptidase CXL13_10780 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase CXL13_10785 ENOG4105CA9 Pyruvate kinase CXL13_10790 ENOG4106KNT transcriptional regulator CXL13_10800 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase CXL13_10805 ENOG4105C01 Dihydroxy-acid dehydratase CXL13_10810 ENOG4108UHU Aldolase CXL13_10820 ENOG4105X2V dna damage-inducible protein CXL13_10830 ENOG4108Q2J Inner membrane protein YebE CXL13_10835 ENOG4105CUG Oligopeptidase b CXL13_10840 ENOG4105UMD exodeoxyribonuclease X CXL13_10845 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase CXL13_10850 ENOG4105MPK DNA polymerase III subunit theta CXL13_10855 ENOG4105FXM Copper resistance protein CXL13_10860 ENOG4108PNC copper resistance CXL13_10865 ENOG4105NKT exported protein CXL13_10910 ENOG4105C22 threonyL-tRNA synthetase CXL13_10930 ENOG41064WM Uncharacterized protein YcgX CXL13_10940 ENOG4106EWC guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling CXL13_10950 ENOG4108R1E Serine threonine protein phosphatase 1 CXL13_10955 ENOG4105UVW uncharacterized protein yebW CXL13_10960 ENOG4105WT8 Protein of unknown function (DUF1480) CXL13_10970 ENOG4105DY2 Paraquat-inducible protein b CXL13_10975 ENOG4105H2K paraquat-inducible protein a CXL13_10980 ENOG4108ZGC gaf domain protein CXL13_10990 ENOG4105CN1 protease CXL13_11000 ENOG4105C0R drug resistance transporter emrb qaca subfamily CXL13_11005 ENOG4105J4Q Transcriptional regulator CXL13_11020 ENOG4105Q3Y exported protein CXL13_11025 ENOG410610J Protein of unknown function (DUF2627) CXL13_11030 ENOG4105VEQ Cold shock protein CXL13_11035 ENOG4105CJN penicillin-binding protein CXL13_11040 ENOG4105DHI Methyltransferase CXL13_11060 ENOG4105F3R pts system mannose fructose sorbose family iid CXL13_11065 ENOG4105ETZ PTS System CXL13_11070 ENOG4108EQA pts system CXL13_11080 ENOG4105EE5 Membrane protein terC CXL13_11085 ENOG4107XTP (EAL) domain protein CXL13_11090 ENOG4105EJQ L-serine dehydratase CXL13_11100 ENOG4105CRQ synthase (Component I) CXL13_11110 ENOG4105M4H endoribonuclease L-psp CXL13_11115 ENOG4105DVT helicase CXL13_11120 ENOG41072GX Peptidase M22 Glycoprotease CXL13_11125 ENOG4105Y4Z Outer Membrane Lipoprotein CXL13_11135 ENOG4105CEY Amp-dependent synthetase and ligase CXL13_11140 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) CXL13_11150 ENOG4107QMS site-determining protein CXL13_11165 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase CXL13_11180 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation CXL13_11205 ENOG4105ED1 spovr family CXL13_11215 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) CXL13_11225 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A CXL13_11235 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) CXL13_11250 ENOG4105D82 Glutamate dehydrogenase CXL13_11260 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii CXL13_11265 ENOG4105C4M (Ubiquinol oxidase) subunit I CXL13_11270 ENOG4105MVP hydrogenase-1 operon protein HyaF CXL13_11275 ENOG4108VXY Hydrogenase-1 operon protein HyaE CXL13_11280 ENOG4108USZ hydrogenase CXL13_11285 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit CXL13_11295 ENOG4105E3S small subunit CXL13_11315 ENOG4105C3G gtp-binding protein CXL13_11325 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria CXL13_11330 ENOG4105CHH sulfate transporter CXL13_11335 ENOG4105C5T Phosphoribosyl pyrophosphate synthase CXL13_11360 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) CXL13_11365 ENOG4108YY7 Invasion gene expression up-regulator SirB CXL13_11370 ENOG41063JG Transcriptional regulator CXL13_11380 ENOG4105EWV Sodium calcium exchanger membrane region CXL13_11385 ENOG4105WS7 Cation transport regulator CXL13_11390 ENOG41090EX DsrE family CXL13_11395 ENOG4105ID0 Putative invasin CXL13_11400 ENOG4105WH1 Two component transcriptional regulator luxr family CXL13_11405 ENOG4105BZU Histidine kinase CXL13_11415 ENOG4105DQQ Major facilitator superfamily MFS_1 CXL13_11420 ENOG4105CRU nitrate reductase, alpha subunit CXL13_11425 ENOG4108IUE nitrate reductase beta subunit CXL13_11430 ENOG4105R3A Nitrate reductase CXL13_11435 ENOG41076YT nitrate reductase, gamma subunit CXL13_11480 ENOG4105CIY formyltetrahydrofolate deformylase CXL13_11485 ENOG4105K5B UPF0225 protein CXL13_11490 ENOG4105D78 K07001 NTE family protein CXL13_11495 ENOG4105I93 response regulator CXL13_11500 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase CXL13_11515 ENOG4108EKI Dehydrogenase CXL13_11520 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein CXL13_11530 ENOG4107QSI ABC, transporter CXL13_11535 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CXL13_11540 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CXL13_11545 ENOG4105C3U ABC transporter CXL13_11550 ENOG4108JQ7 (ABC) transporter CXL13_11555 ENOG4105EYW Ion transport protein CXL13_11570 ENOG4105K9H YciI-like protein CXL13_11575 ENOG410822N TonB family CXL13_11580 ENOG4105NAU thioesterase Superfamily protein CXL13_11595 ENOG4105PI0 Ferredoxin CXL13_11600 ENOG4105EIF outer membrane protein W CXL13_11605 ENOG4105WEF catalase CXL13_11610 ENOG4108N8X transition metal ion binding CXL13_11615 ENOG4108Z9Z response to DNA damage stimulus CXL13_11635 ENOG4105DK0 Indole-3-glycerol phosphate synthase CXL13_11640 ENOG4108EFP Anthranilate synthase component II CXL13_11645 ENOG4105CRQ synthase (Component I) CXL13_11655 ENOG4105DB7 PHP domain protein CXL13_11660 ENOG4107RTD sua5 ycio yrdc ywlc family protein CXL13_11665 ENOG4105FE9 pseudouridine synthase CXL13_11670 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase CXL13_11675 ENOG4105UBK short-chain dehydrogenase reductase CXL13_11680 ENOG4105ERU peptidase CXL13_11685 ENOG4105RKX Protein of unknown function (DUF2498) CXL13_11695 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) CXL13_11700 ENOG4107R11 Transcriptional regulator CXL13_11715 ENOG4107QM5 aconitate hydratase CXL13_11725 ENOG4105EYK Phosphatidylglycerophosphatase B CXL13_11735 ENOG4105Q4A inner membrane protein yciS CXL13_11740 ENOG4105CFV Tetratricopeptide repeat protein CXL13_11750 ENOG4108ZJT translation initiation factor, Sui1 CXL13_11755 ENOG41061RM osmotically inducible lipoprotein CXL13_11760 ENOG4105N2W Transcriptional regulator CXL13_11770 ENOG4105BZU Histidine kinase CXL13_11785 ENOG4105Q4T oxidoreductase CXL13_11790 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH CXL13_11815 ENOG4108JQ2 peptide transport system atp-binding protein CXL13_11820 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein CXL13_11825 ENOG4108EU3 peptide transport system, permease CXL13_11830 ENOG4108I5W peptide transport system, permease protein CXL13_11835 ENOG4108J59 Extracellular solute-binding protein, family 5 CXL13_11840 ENOG4105E51 psp operon transcriptional activator CXL13_11845 ENOG41087YS Phage shock protein A CXL13_11850 ENOG4105YYT phage shock protein B CXL13_11855 ENOG4105FM1 phage shock protein C CXL13_11860 ENOG4105NNG Peripheral inner membrane phage-shock protein CXL13_11865 ENOG4105K8Z Phage shock protein CXL13_11870 ENOG4105CM6 amino acid regulated cytosolic protein CXL13_11880 ENOG4108JU8 Transcriptional regulator CXL13_11885 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) CXL13_11890 ENOG4107S8C mandelate racemase muconate lactonizing CXL13_11895 ENOG4105KXI murein peptide amidase A CXL13_11900 ENOG4107QSI ABC, transporter CXL13_11925 ENOG4105EJC lysr family transcriptional regulator CXL13_11935 ENOG4105C44 Serine transporter CXL13_11940 ENOG4105C28 cystathionine CXL13_11950 ENOG4105HEI LysR family (Transcriptional regulator CXL13_11955 ENOG4105CV8 reductase CXL13_11960 ENOG4105F6U Short-chain dehydrogenase reductase Sdr CXL13_11965 ENOG4108XFH Transcriptional regulator CXL13_11980 ENOG4106PHM regulatory protein CXL13_12000 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) CXL13_12020 ENOG4105D64 Mechanosensitive ion channel CXL13_12025 ENOG4105S5I Membrane CXL13_12030 ENOG4105Q9Y Universal stress protein CXL13_12040 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) CXL13_12045 ENOG4108DG9 Smr protein MutS2 CXL13_12050 ENOG4105C8Q Methyl-accepting chemotaxis CXL13_12065 ENOG4105C1J atp-dependent rna helicase CXL13_12085 ENOG410814C multidrug resistance protein CXL13_12090 ENOG4108RW8 Universal stress protein F CXL13_12100 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) CXL13_12115 ENOG41090X5 Heat shock protein hslJ CXL13_12120 ENOG4105C5I Dehydrogenase CXL13_12125 ENOG4107H52 Dicarboxylate transport CXL13_12130 ENOG410689M (LipO)protein CXL13_12135 ENOG4105WXT Conserved Protein CXL13_12150 ENOG4105CQ7 ATP-dependent helicase CXL13_12155 ENOG4107DB1 DUF218 domain CXL13_12160 ENOG4105CPW cytochrome b561 CXL13_12165 ENOG4108WF3 methyltransferase CXL13_12175 ENOG4105E5Q amino acid AbC transporter CXL13_12185 ENOG4105E5Q amino acid AbC transporter CXL13_12190 ENOG4107R0W ABC transporter CXL13_12200 ENOG4107ZUJ lipid metabolic process CXL13_12230 ENOG4105C8Q Methyl-accepting chemotaxis CXL13_12235 ENOG4105DDW LysR family Transcriptional regulator CXL13_12240 ENOG4105E32 cytoplasmic protein CXL13_12245 ENOG4105EBR Carboxylesterase CXL13_12270 ENOG4108PQ7 sgc region transcriptional regulator CXL13_12275 ENOG4108RK0 3-epimerase CXL13_12280 ENOG4108XBJ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) CXL13_12285 ENOG4106P19 photosystem i assembly btpa CXL13_12290 ENOG4105DT3 PTS system, galactitol-specific IIc component CXL13_12295 ENOG4105K18 The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) CXL13_12300 ENOG4105CN9 Peptidase m42 family protein CXL13_12305 ENOG4108Z9I -acetyltransferase CXL13_12310 ENOG4107WE3 acetyltransferase YdcK CXL13_12315 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein CXL13_12320 ENOG41088CC tellurite resistance protein tehB CXL13_12325 ENOG4108KKZ (LipO)protein CXL13_12330 ENOG4105DKK Benzoate CXL13_12335 ENOG4108JCI Transcriptional regulator CXL13_12340 ENOG4105CFP Peptidase U32 CXL13_12345 ENOG4105RR0 Protein of unknown function (DUF2554) CXL13_12365 ENOG4108UQS dipeptidase CXL13_12370 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family CXL13_12385 ENOG410654E Membrane CXL13_12405 ENOG4105R71 cytoplasmic protein CXL13_12410 ENOG4108T9Y Inner membrane protein ydcZ CXL13_12415 ENOG4108Z7F N-acetyltransferase CXL13_12420 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein CXL13_12430 ENOG4105CHB tonB-dependent Receptor CXL13_12435 ENOG4108NS2 receptor CXL13_12440 ENOG4105SUV lipoprotein YgdR CXL13_12445 ENOG4105C85 amino acid CXL13_12460 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase CXL13_12465 ENOG4105JAB phenazine biosynthesis protein, phzf family CXL13_12470 ENOG4105D0D Nitrate reductase 2, gamma subunit CXL13_12475 ENOG4108NZN Respiratory nitrate reductase 2 delta chain CXL13_12480 ENOG4108IUE nitrate reductase beta subunit CXL13_12485 ENOG4105CRU nitrate reductase, alpha subunit CXL13_12490 ENOG4107QND Nitrite extrusion protein CXL13_12525 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CXL13_12530 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CXL13_12535 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein CXL13_12540 ENOG4108MG3 formate dehydrogenase CXL13_12545 ENOG4105DQ4 alcohol dehydrogenase CXL13_12560 ENOG4105TPS biofilm-dependent modulation protein CXL13_12565 ENOG4108Z9K Osmotically inducible protein CXL13_12570 ENOG4105XXV Acid-resistance protein CXL13_12580 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) CXL13_12595 ENOG4105C87 Aminotransferase class I and II CXL13_12600 ENOG4105DFD Na H antiporter CXL13_12605 ENOG41060NJ transcriptional regulator CXL13_12665 ENOG4108UQ8 endoribonuclease L-psp CXL13_12670 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) CXL13_12680 ENOG4107SCK Monooxygenase CXL13_12695 ENOG4108I5G Major Facilitator superfamily CXL13_12700 ENOG4105CPQ Dehydrogenase CXL13_12705 ENOG4105C6F GntR Family Transcriptional Regulator CXL13_12720 ENOG4105DPX Hydrogenase, large subunit CXL13_12725 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit CXL13_12745 ENOG4105MVP hydrogenase-1 operon protein HyaF CXL13_12770 ENOG4105FFC UPF0187 protein CXL13_12775 ENOG4105M0C cytoplasmic protein CXL13_12785 ENOG4105C26 Dehydrogenase CXL13_12790 ENOG4105EGI Transcriptional regulator CXL13_12810 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes CXL13_12820 ENOG4106DNR multiple antibiotic resistance protein CXL13_12825 ENOG4108594 Permease of the drug metabolite transporter CXL13_12830 ENOG4105E5W Transporter CXL13_12845 ENOG4108YDI single-species biofilm formation on inanimate substrate CXL13_12850 ENOG4108WTK competence damage-inducible protein CXL13_12865 ENOG4105DGW oligopeptidase A CXL13_12870 ENOG4105EMU Dehydrogenase CXL13_12875 ENOG4107XBN GntR Family Transcriptional Regulator CXL13_12880 ENOG41061EV selenium-binding protein YdfZ CXL13_12885 ENOG4105DEI Mannitol dehydrogenase CXL13_12895 ENOG4105CPQ Dehydrogenase CXL13_12915 ENOG4108MK9 spermidine N(1)-acetyltransferase CXL13_12925 ENOG4105KBG Protein of unknown function (DUF1161) CXL13_12930 ENOG4107QY8 reductase CXL13_12935 ENOG4105C3J Cysteine desulfurase CXL13_12940 ENOG4105QAX Iron-sulfur CXL13_12945 ENOG4107KGK dmso reductase anchor subunit CXL13_12950 ENOG4108NEM leader-binding protein dmsD CXL13_12955 ENOG4108U0I binding-protein-dependent transport systems inner membrane Component CXL13_12960 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system CXL13_12965 ENOG4105E90 ABC transporter CXL13_12970 ENOG4108IJ8 ABC transporter CXL13_12975 ENOG4105CMQ Chloride channel CXL13_12980 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) CXL13_12985 ENOG4105DAG ROK family CXL13_12995 ENOG4106NZI LysR family Transcriptional regulator CXL13_13000 ENOG4105D94 Major Facilitator Superfamily CXL13_13010 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap CXL13_13030 ENOG4105DSF transport protein CXL13_13035 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) CXL13_13040 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) CXL13_13045 ENOG4105C5D exported protein CXL13_13050 ENOG4105D5Q Arginine ornithine antiporter CXL13_13055 ENOG4105RA2 Membrane CXL13_13060 ENOG4107EXC regulatoR CXL13_13070 ENOG4105FCK Membrane CXL13_13075 ENOG4105CPN adenine deaminase CXL13_13080 ENOG4105JJR Histidine kinase CXL13_13090 ENOG4105C9Q fumarate hydratase class II CXL13_13095 ENOG4107GFK fumarate CXL13_13100 ENOG4105EIP mannose-6-phosphate isomerase CXL13_13105 ENOG4106J39 exported protein CXL13_13115 ENOG4105C87 Aminotransferase class I and II CXL13_13125 ENOG4105D9R oxidoreductase CXL13_13130 ENOG4106C6R beta-lactam resistance protein CXL13_13140 ENOG4105M9B inner membrane protein ydgK CXL13_13165 ENOG4108UQQ Electron transport complex CXL13_13175 ENOG4105CSM endonuclease III CXL13_13180 ENOG4105DUX Transporter CXL13_13185 ENOG4108K3A Glutathione S-transferase CXL13_13205 ENOG410642K Lysozyme inhibitor CXL13_13215 ENOG4108XTF Outer Membrane Lipoprotein CXL13_13230 ENOG4105Y49 secretion protein, HlyD family CXL13_13235 ENOG4105DSW Fusaric acid resistance protein CXL13_13240 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CXL13_13245 ENOG4107RGM aldo keto reductase CXL13_13250 ENOG4105XZD Fe-S protein CXL13_13255 ENOG4108WUH Transcriptional regulator, TetR family CXL13_13260 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase CXL13_13265 ENOG4108UYE Lactoylglutathione lyase CXL13_13280 ENOG4105M2J Glutaredoxin CXL13_13285 ENOG4105K4H Nlp p60 protein CXL13_13290 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CXL13_13310 ENOG4105F52 Transcriptional regulator CXL13_13315 ENOG4105CZQ inner membrane transport protein YdhC CXL13_13320 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase CXL13_13325 ENOG4108R6K riboflavin synthase, subunit alpha CXL13_13345 ENOG4108IUF type iii secretion CXL13_13350 ENOG4108TN6 type iii secretion CXL13_13355 ENOG41083GP type iii secretion CXL13_13360 ENOG4108HHI Type III secretion system protein CXL13_13365 ENOG41063Q7 Type III secretion system protein CXL13_13380 ENOG4108JIR Flagellum-specific ATP synthase CXL13_13390 ENOG4106H1D secretion system apparatus protein CXL13_13395 ENOG4105UQF type iii secretion CXL13_13400 ENOG4106563 type III secretion system apparatus protein CXL13_13450 ENOG4106FZW pathogenicity island effector protein CXL13_13455 ENOG4108SZ7 secretion system effector CXL13_13465 ENOG4105ZQI secreted protein CXL13_13495 ENOG4105BZU Histidine kinase CXL13_13505 ENOG4108XDN Transcriptional regulator CXL13_13510 ENOG4107SEY Conserved Protein CXL13_13515 ENOG4105RFR Protein of unknown function (DUF2767) CXL13_13520 ENOG4108ZXC Two component transcriptional regulator, luxr family CXL13_13525 ENOG4106AFQ Histidine kinase CXL13_13530 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein CXL13_13535 ENOG4106WHD Tetrathionate reductase CXL13_13540 ENOG4105DB1 molybdopterin oxidoreductase CXL13_13545 ENOG4108RVA ribokinase CXL13_13555 ENOG4107RCM Releases the N-terminal proline from various substrates (By similarity) CXL13_13560 ENOG4105CUB amino acid CXL13_13570 ENOG4105CA9 Pyruvate kinase CXL13_13595 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein CXL13_13610 ENOG4105JRK feS assembly protein SufD CXL13_13615 ENOG4105C3K feS assembly ATPase SufC CXL13_13620 ENOG4105DIW FeS assembly protein SUFB CXL13_13625 ENOG4108Z4V iron-sulfur cluster assembly CXL13_13630 ENOG4108ETY sodium dicarboxylate symporter CXL13_13635 ENOG410671Z uncharacterized protein ydiH CXL13_13640 ENOG4105KA0 thioesterase Superfamily protein CXL13_13645 ENOG4105CQB FAD linked oxidase domain protein CXL13_13650 ENOG4105IPI Membrane CXL13_13660 ENOG4105SUA Ydil protein CXL13_13665 ENOG4105EMV Major Facilitator CXL13_13670 ENOG4105EMV Major Facilitator CXL13_13685 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) CXL13_13690 ENOG4105C1G acyl-Coa dehydrogenase CXL13_13695 ENOG4105W4W Transcriptional regulator CXL13_13700 ENOG4105CV7 Electron transfer flavoprotein CXL13_13705 ENOG4105C10 Electron transfer flavoprotein CXL13_13710 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase CXL13_13715 ENOG41090P5 ferredoxin-like protein CXL13_13720 ENOG4105CEY Amp-dependent synthetase and ligase CXL13_13725 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) CXL13_13735 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) CXL13_13740 ENOG4106EDX Hemin uptake protein CXL13_13755 ENOG4108QBX (LipO)protein CXL13_13765 ENOG4108V06 Glutathione peroxidase CXL13_13775 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) CXL13_13780 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) CXL13_13795 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) CXL13_13800 ENOG41082NX 50s ribosomal protein l35 CXL13_13805 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) CXL13_13830 ENOG4108NE3 Salt-induced outer membrane protein CXL13_13835 ENOG4105DE4 1-phosphofructokinase CXL13_13840 ENOG4105P10 Uncharacterized protein ydiZ CXL13_13845 ENOG4105FGM Fructosamine kinase CXL13_13850 ENOG4107PN8 YfeABCD locus regulator CXL13_13855 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 CXL13_13860 ENOG4107K5X Membrane-bound metal-dependent hydrolase CXL13_13865 ENOG4108ETY sodium dicarboxylate symporter CXL13_13875 ENOG4105CH6 catalase CXL13_13885 ENOG4105F8D glycoside hydrolase family 4 CXL13_13890 ENOG4105EZV Transcriptional regulator CXL13_13895 ENOG4105VCP PTS System CXL13_13900 ENOG4105CK1 PTS System CXL13_13905 ENOG4105VZJ PTS System CXL13_13915 ENOG4105KKI DNA-binding transcriptional activator OsmE CXL13_13925 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) CXL13_13930 ENOG4108SPG Periplasmic Protein CXL13_13945 ENOG4105EY2 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity) CXL13_13950 ENOG4105C26 Dehydrogenase CXL13_13970 ENOG4105CGK Exodeoxyribonuclease III CXL13_13975 ENOG4105M6F mutator MutT protein CXL13_13980 ENOG4105MTM Protein of unknown function (DUF1496) CXL13_13985 ENOG4105D82 Glutamate dehydrogenase CXL13_13990 ENOG4108IYH Dna topoisomerase CXL13_13995 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) CXL13_14000 ENOG41069NU Nitroreductase CXL13_14005 ENOG4105D07 Signal peptide peptidase, SppA CXL13_14010 ENOG4105HDK L-asparaginase CXL13_14015 ENOG4108RWI nicotinamidase CXL13_14020 ENOG4105VUT cytoplasmic protein CXL13_14030 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase CXL13_14040 ENOG4105DSB aldose 1-epimerase CXL13_14045 ENOG4105CV8 reductase CXL13_14050 ENOG4105C4X radical SAM domain protein CXL13_14055 ENOG4105GNX MltA-interacting MipA family protein CXL13_14060 ENOG4105CYN Serine protein kinase CXL13_14075 ENOG4108KHP Diguanylate cyclase CXL13_14080 ENOG4108KXH Ybak prolyl-tRNA synthetase associated CXL13_14095 ENOG4105R1U AraC Family Transcriptional Regulator CXL13_14100 ENOG4105DJ2 Major Facilitator Superfamily CXL13_14105 ENOG4105K78 MarR family Transcriptional regulator CXL13_14115 ENOG4105UCG Domain of unknown function (DUF333) CXL13_14120 ENOG4106G4W CXL13_14125 ENOG4105Y3U Transglycosylase-associated protein CXL13_14140 ENOG4105YP6 Domain of unknown function (DUF1869) CXL13_14145 ENOG4108YS1 cytoplasmic protein CXL13_14160 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) CXL13_14175 ENOG4108Z6Z Transcriptional regulator CXL13_14190 ENOG4108MEK Metal-binding protein YodA CXL13_14205 ENOG4105D64 Mechanosensitive ion channel CXL13_14210 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) CXL13_14215 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) CXL13_14240 ENOG4108VKM cytochrome b561 CXL13_14250 ENOG4108ZNX Heat shock protein CXL13_14280 ENOG4105H38 Membrane CXL13_14300 ENOG41060EU Cold shock-like protein CXL13_14305 ENOG4106F2Y RICIN CXL13_14310 ENOG4105Y50 Virulence Protein CXL13_14350 ENOG4108HMX isocitrate dehydrogenase (NADP) CXL13_14355 ENOG4108R99 pseudouridine synthase CXL13_14380 ENOG4107QTF adenylosuccinate lyase CXL13_14395 ENOG4105EZE Cupin 4 family protein CXL13_14415 ENOG4105F38 ABC transporter, permease CXL13_14425 ENOG4105D38 putrescine abc transporter CXL13_14430 ENOG4107RUE extracellular solute-binding protein family 1 CXL13_14435 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) CXL13_14445 ENOG4105D60 lipoprotein releasing system transmembrane protein CXL13_14455 ENOG4105D60 lipoprotein releasing system transmembrane protein CXL13_14460 ENOG4108JA2 transcriptioN-repair coupling factor CXL13_14465 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein CXL13_14470 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction CXL13_14475 ENOG4108IND Tetr family transcriptional regulator CXL13_14480 ENOG4107MBR 17 kDa surface antigen CXL13_14485 ENOG4105CEP NADH dehydrogenase CXL13_14505 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) CXL13_14510 ENOG41090DQ Lipoprotein CXL13_14515 ENOG4105K59 histidine triad (HIT) protein CXL13_14520 ENOG4105CNM Receptor CXL13_14525 ENOG4105CI1 PTS System CXL13_14530 ENOG4105F8V Hydrolase, tatD family CXL13_14535 ENOG4107QRG dna polymerase iii CXL13_14545 ENOG4105HHA aminodeoxychorismate lyase CXL13_14550 ENOG4105YAZ 4-amino-4-deoxychorismate lyase CXL13_14555 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CXL13_14560 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) CXL13_14565 ENOG4105CHR reductase CXL13_14570 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase CXL13_14590 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein CXL13_14595 ENOG4108UHJ MAF-like protein CXL13_14610 ENOG4105EI2 Pseudouridine synthase CXL13_14615 ENOG41071G1 Uncharacterized protein YceQ CXL13_14620 ENOG4107QQB Ribonuclease E CXL13_14630 ENOG4105DTJ flagellar hook-associated protein CXL13_14635 ENOG4105E1Q flagellar hook-associated protein CXL13_14640 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj CXL13_14655 ENOG4105CGA flagellar basal-body rod protein FlgG CXL13_14660 ENOG4108KPB Flagellar basal-body rod protein FlgF CXL13_14665 ENOG4105BZE flagellar hook protein, FlgE CXL13_14670 ENOG4105W00 Flagellar hook capping protein CXL13_14675 ENOG4108ZC9 flagellar basal-body rod protein flgc CXL13_14680 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) CXL13_14690 ENOG4105CKS Flagella basal body P-ring formation protein flgA CXL13_14695 ENOG4105M9M anti-sigma28 factor FlgM CXL13_14700 ENOG4105QVD Flagella synthesis protein FlgN CXL13_14705 ENOG4105CJR Integral membrane protein (MviN CXL13_14710 ENOG4105EP9 oxidoreductase CXL13_14720 ENOG4105D9U N-acetyltransferase CXL13_14730 ENOG4105E9S glutaredoxin 2 CXL13_14735 ENOG4105F3T (LipO)protein CXL13_14745 ENOG4105MEA DNA damage-inducible protein i CXL13_14750 ENOG4105PVA Biofilm formation regulatory protein BssS CXL13_14760 ENOG4106974 biofilm formation CXL13_14770 ENOG4105DS1 cytochrome b561 CXL13_14775 ENOG4108YYC ycei family CXL13_14785 ENOG4105D1S lipid A biosynthesis CXL13_14800 ENOG4108W47 Acidic protein msyB CXL13_14805 ENOG4105NAC (LipO)protein CXL13_14810 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) CXL13_14825 ENOG4107RZC phospholipase d CXL13_14860 ENOG41086KC Transcriptional regulator CXL13_14865 ENOG4108XDW curli assembly protein CsgE CXL13_14870 ENOG4108WYR Curli production assembly transport component, CsgF CXL13_14875 ENOG4105P8Q Curli production assembly transport component CsgG CXL13_14880 ENOG4108UQ5 membrane protein YcdZ CXL13_14885 ENOG4107XHZ cytoplasmic chaperone TorD family protein CXL13_14945 ENOG4105D5M phosphate starvation-inducible protein CXL13_14955 ENOG4105CK7 Sodium proline symporter CXL13_14975 ENOG4108R86 Transcriptional regulator CXL13_14980 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 CXL13_14990 ENOG4105XH3 CXL13_14995 ENOG4105D6F Phosphatase CXL13_15000 ENOG4105N2G alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen CXL13_15005 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) CXL13_15010 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) CXL13_15080 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase CXL13_15085 ENOG4105C26 Dehydrogenase CXL13_15095 ENOG4108V8F Transcriptional regulator, MarR family CXL13_15100 ENOG4105EFA 4-hydroxyphenylacetate CXL13_15105 ENOG4107UWN reductase CXL13_15120 ENOG4105VT2 5-hydroxyisourate hydrolase CXL13_15125 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CXL13_15130 ENOG4107ZY3 Histidine kinase CXL13_15145 ENOG4106YSC CXL13_15150 ENOG4108N4M Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns 3-P and prevents the transition of PtdIns 3-P to PtdIns 3,5-P2. It is one of the known effectors injected by Salmonella into the host cell and is required for invasion and for an efficient generation and maintenance of Salmonella-containing vacuole (SVC). Alteration of the phosphoinositide composition of the plasma membrane causes membrane ruffling and actin cytoskeleton rearrangements. The persistence of PtdIns 3-P diverts the SCV from the endocytic pathway resulting in enlarged vesicles, which are essential to create a favorable environment where Salmonella can replicate and avoid immune defenses of the host cell CXL13_15160 ENOG41084BJ Pentapeptide repeat protein CXL13_15175 ENOG4108MN8 Membrane CXL13_15185 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 CXL13_15195 ENOG4108V1U phospholipid-binding protein CXL13_15210 ENOG4105K4P CoA-binding domain protein CXL13_15225 ENOG41088T4 Helicase IV CXL13_15230 ENOG410901E Membrane CXL13_15235 ENOG4105EM2 membrane CXL13_15240 ENOG4108RZ1 DNA transformation protein CXL13_15250 ENOG4105UYK outer membrane protein a CXL13_15260 ENOG4105DAN ATP-dependent protease CXL13_15270 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) CXL13_15275 ENOG4108Q2G (LipO)protein CXL13_15280 ENOG4105DY2 Paraquat-inducible protein b CXL13_15285 ENOG4105F1S paraquat-inducible protein a CXL13_15290 ENOG4105C5H ABC transporter CXL13_15300 ENOG4105QVC MOSC domain-containing protein CXL13_15305 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) CXL13_15315 ENOG4105CD8 aminopeptidase N CXL13_15330 ENOG4107RCH Diaminopropionate ammonia-lyase CXL13_15350 ENOG4105FCK Membrane CXL13_15355 ENOG4105CGF Aromatic amino acid aminotransferase CXL13_15360 ENOG4105C5X domain protein CXL13_15365 ENOG4105EAQ (twin-arginine translocation) pathway signal CXL13_15375 ENOG4105DIT ErfK YbiS YcfS YnhG family protein CXL13_15385 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) CXL13_15395 ENOG4106371 Methyltransferase CXL13_15400 ENOG4107S90 membrAne CXL13_15405 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups CXL13_15420 ENOG4105T0Z Conserved Protein CXL13_15435 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 CXL13_15440 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) CXL13_15445 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) CXL13_15455 ENOG4108K0D peptidase, M48 CXL13_15470 ENOG4107VMU Membrane CXL13_15475 ENOG4105DDY UPF0142 protein ycaO CXL13_15480 ENOG4105TMB Formate nitrite transporter CXL13_15485 ENOG4105C6N Formate acetyltransferase CXL13_15490 ENOG4105GUS CXL13_15495 ENOG4105F1A Pyruvate formate-lyase CXL13_15500 ENOG4105E5D amino acid CXL13_15510 ENOG4107KGK dmso reductase anchor subunit CXL13_15515 ENOG4105QAX Iron-sulfur CXL13_15520 ENOG4107QY8 reductase CXL13_15530 ENOG4105D1H recombination factor protein RarA CXL13_15540 ENOG4105CNU cell division protein FtsK CXL13_15545 ENOG4105EW9 transcriptional regulator AsnC family CXL13_15555 ENOG4105C3M thioredoxin reductase CXL13_15560 ENOG4108JJ9 ABC, transporter CXL13_15565 ENOG4108JJ8 (ABC) transporter CXL13_15580 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) CXL13_15585 ENOG4105HEI LysR family (Transcriptional regulator CXL13_15590 ENOG4105EUB pirin domain protein CXL13_15595 ENOG4105CHJ isochorismatase hydrolase CXL13_15610 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CXL13_15620 ENOG4105VEQ Cold shock protein CXL13_15630 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) CXL13_15635 ENOG4105DJY efflux transporter, rnd family, mfp subunit CXL13_15640 ENOG4108MJ5 VirK protein CXL13_15645 ENOG4105CPB ATP-dependent endonuclease of the OLD family CXL13_15655 ENOG4105DWU Membrane CXL13_15665 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) CXL13_15670 ENOG4105C7K acetolactate synthase CXL13_15675 ENOG4105C5W Aldolase CXL13_15680 ENOG4105CGD Nad-dependent epimerase dehydratase CXL13_15685 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase CXL13_15690 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase CXL13_15700 ENOG41064MM (LipO)protein CXL13_15705 ENOG4105E5Z arginine transporter ATP-binding subunit CXL13_15710 ENOG4106PMH Extracellular solute-binding protein family 3 CXL13_15715 ENOG4105GBT ABC transporter CXL13_15720 ENOG4105DMR ABC, transporter CXL13_15725 ENOG4106TNF Periplasmic binding protein CXL13_15755 ENOG4105RBQ inner membrane protein ybjO CXL13_15760 ENOG4105D38 putrescine abc transporter CXL13_15765 ENOG4105F38 ABC transporter, permease CXL13_15770 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CXL13_15775 ENOG4107RUE extracellular solute-binding protein family 1 CXL13_15780 ENOG4108RMJ sensory transduction regulator CXL13_15790 ENOG4108DBC nitroreductase CXL13_15795 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress CXL13_15800 ENOG41090BQ Glutaredoxin CXL13_15805 ENOG4105GWF inner membrane protein YbjM CXL13_15825 ENOG4108RFG Tetr family transcriptional regulator CXL13_15830 ENOG4106UW1 Major Facilitator superfamily CXL13_15835 ENOG4108HCJ Hydrolase CXL13_15840 ENOG4107QF7 multi-drug CXL13_15845 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase CXL13_15850 ENOG4107FB0 transcriptional regulator DeoR family CXL13_15855 ENOG4105DZ1 carboxypeptidase CXL13_15860 ENOG4108TGY Glutathione S-transferase CXL13_15865 ENOG4105D8V Glucose sorbosone dehydrogenase CXL13_15870 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway CXL13_15890 ENOG4105DEF Extracellular solute-binding protein, family 5 CXL13_15895 ENOG4108JQ6 ABC transporter CXL13_15900 ENOG4105D44 asparaginase CXL13_15905 ENOG4105CVM Molybdenum cofactor synthesis domain protein CXL13_15910 ENOG4105D06 uba thif-type nad fad binding protein CXL13_15915 ENOG4105F1A Pyruvate formate-lyase CXL13_15920 ENOG4105C6N Formate acetyltransferase CXL13_15925 ENOG4108HCJ Hydrolase CXL13_15930 ENOG41072TH Protein of unknown function (DUF1479) CXL13_15955 ENOG4105C5H ABC transporter CXL13_15960 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein CXL13_15965 ENOG4105F4P )-transporter CXL13_15970 ENOG4105KST dependent repressor CXL13_15980 ENOG4108I6E Sulfatase CXL13_15985 ENOG4108T1M outer membrane protein x CXL13_16005 ENOG4107R0W ABC transporter CXL13_16010 ENOG4105E5Q amino acid AbC transporter CXL13_16015 ENOG4105CDA abc transporter atp-binding protein CXL13_16020 ENOG4105D8X mechanosensitive ion channel CXL13_16030 ENOG4105KSC Transcriptional regulator, TraR DksA family CXL13_16035 ENOG4105VR4 UPF0379 protein ybiJ CXL13_16040 ENOG4108MTB glycosyl transferase family CXL13_16045 ENOG4105DVT helicase CXL13_16050 ENOG4105C1J atp-dependent rna helicase CXL13_16055 ENOG4108EKI Dehydrogenase CXL13_16075 ENOG4105DJB Major Facilitator Superfamily CXL13_16080 ENOG4108PZW LysR family Transcriptional regulator CXL13_16085 ENOG4107MVR Transcriptional regulator CXL13_16095 ENOG4105CJ1 ABC, transporter CXL13_16100 ENOG4107QWP ABC-2 type transporter CXL13_16105 ENOG4107QWP ABC-2 type transporter CXL13_16110 ENOG4105I9U inner membrane protein ybhQ CXL13_16115 ENOG4105X23 Endonuclease Exonuclease phosphatase CXL13_16120 ENOG4105DZQ phospholipase D Transphosphatidylase CXL13_16125 ENOG4107UXM Membrane CXL13_16150 ENOG4105HFZ Membrane CXL13_16155 ENOG4108ZAF Molybdopterin CXL13_16160 ENOG4105M00 molybdopterin converting factor, subunit 1 CXL13_16170 ENOG4108RIR Molybdenum cofactor biosynthesis protein CXL13_16180 ENOG4105CHW UPF0052 protein CXL13_16200 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) CXL13_16205 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) CXL13_16220 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) CXL13_16225 ENOG4108V1U phospholipid-binding protein CXL13_16255 ENOG4105NBR Pectinesterase CXL13_16265 ENOG4108K4B hydrolase CXL13_16275 ENOG4105E0C molybdate abc transporter CXL13_16280 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein CXL13_16285 ENOG410680R Protein of unknown function (DUF2592) CXL13_16290 ENOG4105F4R Transcriptional regulator mode CXL13_16295 ENOG4105DKW ABC transporter CXL13_16305 ENOG4105CMR udp-glucose 4-epimerase CXL13_16310 ENOG4105F0Z galactose-1-phosphate uridylyltransferase CXL13_16320 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) CXL13_16335 ENOG4105E0A ABC, transporter CXL13_16340 ENOG4105EHG Permease protein CXL13_16345 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase CXL13_16350 ENOG4105D9Q decarboxylase (Beta subunit) CXL13_16355 ENOG4107QSA Oxaloacetate decarboxylase CXL13_16365 ENOG4107QWE )-transporter CXL13_16380 ENOG4106DSS Tartrate dehydratase subunit alpha CXL13_16385 ENOG4107GFK fumarate CXL13_16390 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) CXL13_16395 ENOG4105JND homeobox protein CXL13_16400 ENOG4105PGM cation diffusion facilitator family transporter CXL13_16405 ENOG4106Z1T Nicotinamide Mononucleotide Transporter CXL13_16440 ENOG4105UFD tol-pal system protein YbgF CXL13_16445 ENOG4105KCK Peptidoglycan-associated lipoprotein CXL13_16455 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA CXL13_16460 ENOG4105M8F Biopolymer transport protein exbD tolR CXL13_16465 ENOG4105E02 MotA TolQ exbB proton channel CXL13_16470 ENOG4107YD3 Thioesterase CXL13_16475 ENOG4105KJB cyd operon protein YbgE CXL13_16490 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii CXL13_16495 ENOG4105C4M (Ubiquinol oxidase) subunit I CXL13_16510 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha CXL13_16520 ENOG4105C7S Dehydrogenase CXL13_16525 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 CXL13_16530 ENOG4105E33 succinate dehydrogenase CXL13_16535 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) CXL13_16540 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein CXL13_16545 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit CXL13_16560 ENOG4105BZN citrate synthase CXL13_16565 ENOG4108KK1 membrane protein AbrB duplication CXL13_16575 ENOG4105E7W lamb ycsf family protein CXL13_16580 ENOG4107R7A Allophanate hydrolase subunit 2 CXL13_16585 ENOG4105P4J Allophanate hydrolase, subunit 1 CXL13_16590 ENOG4107QNR UPF0135 protein CXL13_16605 ENOG4105CVP deoxyribo-dipyrimidine photolyase CXL13_16610 ENOG4105XIQ Protein of unknown function (DUF2517) CXL13_16635 ENOG4105C08 Histidine kinase CXL13_16640 ENOG4105EEX Two component transcriptional regulator (Winged helix family CXL13_16645 ENOG4105CXN decarboxylase CXL13_16650 ENOG4105D5Q Arginine ornithine antiporter CXL13_16660 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 CXL13_16665 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) CXL13_16670 ENOG4105EV9 Alpha Beta Hydrolase CXL13_16675 ENOG4105NNH LexA regulated protein CXL13_16680 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) CXL13_16685 ENOG41090R7 Ferric uptake CXL13_16690 ENOG4106P55 Transcriptional regulator CXL13_16695 ENOG4107EFR Flavocytochrome c CXL13_16700 ENOG41079YP Citrate utilization protein b CXL13_16705 ENOG4105CSH Transporter CXL13_16710 ENOG4105GX6 (LipO)protein CXL13_16715 ENOG4105J5J Outer membrane porin CXL13_16730 ENOG4105CI1 PTS System CXL13_16740 ENOG4105CE4 GlcNAc 6-P deacetylase CXL13_16745 ENOG4105E2R ROK family CXL13_16750 ENOG4105D4U had-superfamily hydrolase, subfamily iia CXL13_16755 ENOG4105CAQ asparagine synthetase CXL13_16800 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family CXL13_16810 ENOG4105C9A Phoh family CXL13_16820 ENOG4108JU5 Magnesium and cobalt efflux protein CXL13_16825 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) CXL13_16830 ENOG4107RP9 extracellular solute-binding protein, family 3 CXL13_16835 ENOG4105EAD ABC transporter CXL13_16840 ENOG4105DRP amino acid AbC transporter CXL13_16845 ENOG4105CDA abc transporter atp-binding protein CXL13_16860 ENOG4105F7F Chaperone CXL13_16865 ENOG4105QFC Hsc56 co-chaperone of HscC CXL13_16870 ENOG41069CF Protein of unknown function (DUF1266) CXL13_16875 ENOG4105QFC Hsc56 co-chaperone of HscC CXL13_16880 ENOG41069CF Protein of unknown function (DUF1266) CXL13_16890 ENOG4107PAI alpha helical protein CXL13_16895 ENOG4108JUB Transcriptional regulator CXL13_16900 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) CXL13_16925 ENOG4105DJF DNA polymerase III, delta' subunit CXL13_16930 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) CXL13_16935 ENOG4107QZB decarboxylase CXL13_16940 ENOG4108TGR phosphatase CXL13_16945 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) CXL13_16955 ENOG4105CJN penicillin-binding protein CXL13_16960 ENOG4105CNI cell division protein FtsW CXL13_16965 ENOG4105K6T rare lipoprotein A CXL13_16970 ENOG4105DZ1 carboxypeptidase CXL13_16975 ENOG4108Z43 UPF0250 protein CXL13_16985 ENOG41064T2 transcriptional regulator, lysR family CXL13_17000 ENOG4107QPI nitrilase cyanide hydratase and apolipoprotein n-acyltransferase CXL13_17010 ENOG4105VEQ Cold shock protein CXL13_17020 ENOG4105CEE C4-dicarboxylate transporter CXL13_17025 ENOG4106YYS transcriptional regulatory protein CXL13_17030 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism CXL13_17035 ENOG4105DUA (citrate (pro-3S)-lyase ligase CXL13_17040 ENOG4105XGS Covalent carrier of the coenzyme of citrate lyase (By similarity) CXL13_17045 ENOG4105CI0 Citrate lyase CXL13_17050 ENOG4105CHY citrate lyase, alpha CXL13_17055 ENOG4105YGP holo-ACP synthase CitX CXL13_17065 ENOG4107QPK )-transporter CXL13_17070 ENOG4105KTS ribonuclease CXL13_17080 ENOG4105NXH GreA GreB family elongation factor CXL13_17085 ENOG4105E2A Dehydrogenase CXL13_17090 ENOG4108U51 Universal stress protein CXL13_17100 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein CXL13_17105 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CXL13_17115 ENOG4108JU3 Alkyl hydroperoxide reductase CXL13_17120 ENOG4105D3R alkyl hydroperoxide reductase CXL13_17125 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase CXL13_17135 ENOG4105DQS Transcriptional regulator CXL13_17140 ENOG4105BZV Phosphoadenosine phosphosulfate reductase CXL13_17145 ENOG4105GTN ParB Domain Protein Nuclease CXL13_17150 ENOG4105CHM Aminotransferase CXL13_17155 ENOG4107SCQ Iron-containing alcohol dehydrogenase CXL13_17160 ENOG4105VCD cytoplasmic protein CXL13_17165 ENOG4105D22 carbon starvation protein CXL13_17175 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase CXL13_17180 ENOG4105WQI isochorismatase CXL13_17185 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase CXL13_17190 ENOG4105E4F Isochorismate synthase CXL13_17195 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein CXL13_17200 ENOG4105E8G Major facilitator Superfamily CXL13_17205 ENOG4105DQ5 transport system permease protein CXL13_17210 ENOG4105TVJ transport system, permease CXL13_17215 ENOG4105E0A ABC, transporter CXL13_17220 ENOG4108QY5 Ferric enterobactin transport protein CXL13_17225 ENOG4105C0W non-ribosomal peptide synthetase CXL13_17230 ENOG41085A6 mbth domain-containing protein CXL13_17235 ENOG4105E93 esterase CXL13_17240 ENOG4107RNH Outer membrane receptor FepA CXL13_17245 ENOG4108TSE Transferase CXL13_17255 ENOG4105WQ6 Membrane CXL13_17260 ENOG4105HFT AraC family transcriptional regulator CXL13_17265 ENOG41067SE Tetr family transcriptional regulator CXL13_17270 ENOG4105MSB protein, conserved in bacteria CXL13_17275 ENOG4108RCM Nitroreductase CXL13_17295 ENOG4105F3R pts system mannose fructose sorbose family iid CXL13_17305 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine CXL13_17310 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CXL13_17325 ENOG4105CUY Mechanosensitive ion channel CXL13_17330 ENOG4105C85 amino acid CXL13_17340 ENOG4108KBJ Inner membrane protein YkgB CXL13_17345 ENOG41066GK UPF0379 protein ykgI CXL13_17350 ENOG4107QN2 dihydrolipoyl dehydrogenase CXL13_17355 ENOG4108K01 transcriptional regulator CXL13_17375 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) CXL13_17380 ENOG4105CKK Glycosyl transferase, family 2 CXL13_17405 ENOG4105CKK Glycosyl transferase, family 2 CXL13_17410 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) CXL13_17425 ENOG4108KU3 Integrase CXL13_17440 ENOG4106KCD HTH_LUXR CXL13_17450 ENOG4106721 fimbriae Y protein CXL13_17455 ENOG4108Q9V regulatoR CXL13_17460 ENOG4108ZI2 Fimbrial protein CXL13_17465 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) CXL13_17470 ENOG4105CW0 outer membrane usher protein CXL13_17475 ENOG4108AF8 Chaperone CXL13_17485 ENOG4108WDE Fimbrial protein CXL13_17500 ENOG4105WQ3 Rna-binding protein CXL13_17505 ENOG4105S2T inner membrane protein YbcI CXL13_17525 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) CXL13_17540 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) CXL13_17545 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit CXL13_17550 ENOG4105C5B carbamate kinase CXL13_17555 ENOG4105G5A Protein of unknown function (DUF2877) CXL13_17560 ENOG4107REC cytoplasmic protein CXL13_17565 ENOG4107R1Q Membrane protein FdrA CXL13_17570 ENOG4105DG4 malate L-lactate dehydrogenase CXL13_17575 ENOG4105CE7 Amidase, hydantoinase carbamoylase family CXL13_17580 ENOG4105S0E allantoin catabolism protein CXL13_17585 ENOG4105BZW Glycerate kinase CXL13_17590 ENOG4105DTE Xanthine uracil vitamin C permease CXL13_17600 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease CXL13_17610 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase CXL13_17615 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) CXL13_17620 ENOG41060W2 glyoxylate carboligase CXL13_17645 ENOG4108UMI ABC transporter, permease CXL13_17655 ENOG4105D01 (LipO)protein CXL13_17665 ENOG4105CV6 ABC transporter, permease CXL13_17670 ENOG4108I0Y (ABC) transporter CXL13_17675 ENOG4108UJV acyl-CoA thioesterase i CXL13_17680 ENOG4105E1F short-chain dehydrogenase reductase CXL13_17685 ENOG4107QR8 Thioredoxin CXL13_17690 ENOG4105C4B ABC transporter, permease CXL13_17695 ENOG41083J0 (ABC) transporter CXL13_17700 ENOG4107QX8 SPFH domain, Band 7 family protein CXL13_17705 ENOG4105G5H Membrane CXL13_17710 ENOG4108Z6Z Transcriptional regulator CXL13_17715 ENOG4105C59 p-type ATPase CXL13_17725 ENOG4105MBR gumn family CXL13_17730 ENOG4108Z66 YbaK ebsC protein CXL13_17735 ENOG4105CGH 5'-nucleotidase CXL13_17740 ENOG4105EU0 Major facilitator Superfamily CXL13_17745 ENOG4105CKD glutathione-regulated potassium-efflux system protein CXL13_17750 ENOG4107RE1 Inosine-guanosine kinase CXL13_17755 ENOG4105F2M alpha beta hydrolase fold-3 domain protein CXL13_17790 ENOG4107QMP dna polymerase iii subunits gamma and tau CXL13_17805 ENOG4105WD1 Membrane CXL13_17810 ENOG4108URS primosomal replication protein n'' CXL13_17815 ENOG4106428 Protein of unknown function (DUF2496) CXL13_17820 ENOG4105DNE Transposase CXL13_17825 ENOG4105EGS Mechanosensitive ion channel CXL13_17830 ENOG4108IG5 Transcriptional regulator CXL13_17835 ENOG4105C1P efflux transporter, rnd family, mfp subunit CXL13_17840 ENOG4105BZS acriflavin resistance protein CXL13_17845 ENOG4108UKR Biofilm formation regulator YbaJ CXL13_17855 ENOG4108UW5 maltose o-acetyltransferase CXL13_17860 ENOG4105GSJ Inner membrane protein ylaC CXL13_17875 ENOG41066DG (EAL) domain protein CXL13_17885 ENOG41080UX Methyltransferase CXL13_17890 ENOG4108MNP Glycoprotein polysaccharide metabolism CXL13_17895 ENOG4105C29 acyl-CoA thioesterase CXL13_17900 ENOG4105BZU Histidine kinase CXL13_17905 ENOG4108YZA Nitrogen regulatory protein pii CXL13_17910 ENOG4105BZ1 (ABC) transporter CXL13_17915 ENOG4105BZ1 (ABC) transporter CXL13_17920 ENOG4108XM1 transcriptional regulator AsnC family CXL13_17935 ENOG4108NFA extracellular solute-binding protein CXL13_17945 ENOG4108TGP Thioesterase superfamily protein CXL13_17950 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein CXL13_17955 ENOG4105EIN peptidylprolyl cis-trans isomerase CXL13_17960 ENOG4105K70 DNA-binding protein CXL13_17965 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) CXL13_17990 ENOG4105M85 Bola protein CXL13_18000 ENOG4105IEY (LipO)protein CXL13_18005 ENOG4105EYM Major Facilitator superfamily CXL13_18010 ENOG4105E2S oxidase) subunit II CXL13_18015 ENOG4105BZ9 Cytochrome C oxidase, subunit I CXL13_18020 ENOG4105CCU oxidase (Subunit III) CXL13_18025 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) CXL13_18045 ENOG4107RDB Major Facilitator CXL13_18055 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) CXL13_18060 ENOG4107S0N DJ-1 family CXL13_18075 ENOG4106S9K Transcriptional regulator CXL13_18085 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CXL13_18090 ENOG4108MP3 ABC transporter, permease CXL13_18095 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component CXL13_18110 ENOG4105CTB Polyprenyl synthetase CXL13_18120 ENOG4105CPC Aldo Keto reductase CXL13_18125 ENOG4108ZAI phosphatidylglycerophosphatase a CXL13_18130 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) CXL13_18135 ENOG4107YIM Involved in the transcription termination process (By similarity) CXL13_18145 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) CXL13_18155 ENOG4108KIC (LipO)protein CXL13_18160 ENOG4105DRB nucleoside-specific channel-forming protein CXL13_18175 ENOG4105N1F Hnh endonuclease CXL13_18180 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) CXL13_18190 ENOG4105VIE preprotein translocase, subunit YajC CXL13_18215 ENOG4105D3R alkyl hydroperoxide reductase CXL13_18225 ENOG4107R28 alpha amylase, catalytic region CXL13_18230 ENOG4105C85 amino acid CXL13_18235 ENOG4105CWM branched-chain amino acid transport system II carrier protein CXL13_18240 ENOG4105BZU Histidine kinase CXL13_18245 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CXL13_18250 ENOG4107RH8 nuclease SbcCD subunit D CXL13_18255 ENOG4105EYH Exonuclease CXL13_18260 ENOG4105F27 Major Facilitator CXL13_18265 ENOG4105DKQ ROK family CXL13_18280 ENOG4105HBA AroM protein CXL13_18285 ENOG4105SS3 CXL13_18300 ENOG4105II7 pyrroline-5-carboxylate reductase CXL13_18305 ENOG4105BZU Histidine kinase CXL13_18310 ENOG4105VIF phosphate starvation-inducible protein CXL13_18330 ENOG4105CPF Cell wall formation (By similarity) CXL13_18335 ENOG4105UNH Membrane CXL13_18340 ENOG4105FR5 inner membrane protein YaiY CXL13_18345 ENOG4107QS8 (LipO)protein CXL13_18350 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 CXL13_18360 ENOG4107R6D beta-lactam binding protein AmpH CXL13_18365 ENOG4108PNB DNA-binding transcriptional regulator CXL13_18370 ENOG4108NSE outer membrane autotransporter barrel CXL13_18375 ENOG4105D52 delta-aminolevulinic acid dehydratase CXL13_18380 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) CXL13_18385 ENOG4105DXD 2-methylcitrate dehydratase CXL13_18390 ENOG4105BZN citrate synthase CXL13_18395 ENOG4105CR4 methylisocitrate lyase CXL13_18400 ENOG4108JU7 Transcriptional regulator CXL13_18405 ENOG4105TDT uncharacterized protein yahO CXL13_18410 ENOG4105E82 cytochrome subunit of dehydrogenase CXL13_18430 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii CXL13_18435 ENOG4105C4M (Ubiquinol oxidase) subunit I CXL13_18445 ENOG4105D8D Type III CXL13_18450 ENOG4107QMH DNA methylase CXL13_18455 ENOG4105JHE Major Facilitator Superfamily CXL13_18475 ENOG4105C1P efflux transporter, rnd family, mfp subunit CXL13_18485 ENOG4105ENJ RND efflux system, outer membrane lipoprotein CXL13_18505 ENOG4108T1M outer membrane protein x CXL13_18520 ENOG4105CXC rtn protein CXL13_18545 ENOG4105X0I Fimbrial CXL13_18550 ENOG4108VEV chaperone CXL13_18555 ENOG4105CW0 outer membrane usher protein CXL13_18590 ENOG4105FCK Membrane CXL13_18610 ENOG4105CIN aminoacyl-histidine dipeptidase CXL13_18615 ENOG4108S2Y peptide Chain Release factor CXL13_18630 ENOG4105F7V ErfK ybiS ycfS ynhG family protein CXL13_18635 ENOG4105E7A Glutamine amidotransferase CXL13_18645 ENOG4107QPN acyl-Coa dehydrogenase CXL13_18650 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase CXL13_18660 ENOG4105T40 surface antigen msp4 family protein CXL13_18670 ENOG4105W7K Transcriptional regulator CXL13_18765 ENOG4105CNA YD repeat protein CXL13_18805 ENOG4105CNA YD repeat protein CXL13_18815 ENOG4105CS6 Rhs element vgr protein CXL13_18945 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CXL13_18990 ENOG4108JDX DNA polymerase iii, epsilon subunit CXL13_19000 ENOG4105D1A Methyltransferase CXL13_19010 ENOG4105E9H Lytic Murein transglycosylase CXL13_19015 ENOG4105F2W methyltransferase CXL13_19025 ENOG4105F27 Major Facilitator CXL13_19030 ENOG4105HEI LysR family (Transcriptional regulator CXL13_19035 ENOG4105CV8 reductase CXL13_19070 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase CXL13_19075 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) CXL13_19080 ENOG4108UMI ABC transporter, permease CXL13_19085 ENOG4105D01 (LipO)protein CXL13_19090 ENOG4108R8X outer membrane lipoprotein CXL13_19095 ENOG4108R96 Methyltransferase, YaeB family CXL13_19105 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion CXL13_19110 ENOG4108YZN class I peptide chain release factor CXL13_19115 ENOG4108VWS Yaeq family CXL13_19125 ENOG4105M1T rho-binding antiterminator CXL13_19135 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase CXL13_19140 ENOG4105CXN decarboxylase CXL13_19145 ENOG4108M1A Chitin-binding protein CXL13_19155 ENOG4105C0B DNA polymerase III (alpha subunit) CXL13_19200 ENOG4105KNE Phosphatidate cytidylyltransferase CXL13_19245 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) CXL13_19265 ENOG4105CSH Transporter CXL13_19275 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR CXL13_19280 ENOG4105C0H protease CXL13_19295 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) CXL13_19300 ENOG4105EN6 Membrane CXL13_19320 ENOG4106RDH Protein of unknown function (DUF2544) CXL13_19330 ENOG4105UGQ Fimbrial CXL13_19335 ENOG4105NEV Fimbrial CXL13_19340 ENOG4108FZ9 Chaperone CXL13_19345 ENOG4106PG1 outer membrane usher protein CXL13_19360 ENOG4105S6R Iron-hydroxamate transporter permease subunit CXL13_19365 ENOG4105J76 Periplasmic binding protein CXL13_19370 ENOG4105E0A ABC, transporter CXL13_19375 ENOG4105E0K tonB-dependent siderophore receptor CXL13_19380 ENOG4105BZ4 penicillin-binding protein CXL13_19385 ENOG4105CQ7 ATP-dependent helicase CXL13_19390 ENOG4107XID 2'-5' rna ligase CXL13_19400 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters CXL13_19410 ENOG4105DJ0 Poly(A) Polymerase CXL13_19415 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase CXL13_19440 ENOG4108VEV chaperone CXL13_19445 ENOG4105CW0 outer membrane usher protein CXL13_19450 ENOG4108XEY fimbrial-like adhesin protein CXL13_19470 ENOG4107BJW polysaccharide deacetylase CXL13_19475 ENOG4108YTN IIa component CXL13_19485 ENOG4108UIF Chaperone CXL13_19490 ENOG4105CW0 outer membrane usher protein CXL13_19495 ENOG4108MDY Fimbrial CXL13_19500 ENOG4105E3A (ABC) transporter CXL13_19505 ENOG4105DA5 (ABC) transporter CXL13_19510 ENOG41077A9 carbonic anhydrase CXL13_19515 ENOG4108UGV hypoxanthine phosphoribosyltransferase CXL13_19520 ENOG4105DZG Dehydrogenase CXL13_19525 ENOG4105E3B Multicopper oxidase CXL13_19530 ENOG4108ZRK uncharacterized protein yacC CXL13_19545 ENOG4105MVE transcriptional regulator CXL13_19550 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) CXL13_19555 ENOG4107S2N Type III effector Hrp-dependent CXL13_19560 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) CXL13_19575 ENOG4106HGK Inner membrane protein yieI CXL13_19580 ENOG4107QIJ Aconitate hydratase 2 CXL13_19590 ENOG4108NST exported protein CXL13_19605 ENOG4107QN2 dihydrolipoyl dehydrogenase CXL13_19610 ENOG4107QSN dihydrolipoamide acetyltransferase CXL13_19615 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) CXL13_19620 ENOG41073TP transcriptional regulator CXL13_19625 ENOG4105C85 amino acid CXL13_19630 ENOG4105CT4 transporter CXL13_19635 ENOG4105CUK Alpha-N-arabinofuranosidase (EC 3.2.1.55) CXL13_19640 ENOG4106A72 regulatory protein AmpE CXL13_19650 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase CXL13_19660 ENOG4108ZUW Major pilin subunit CXL13_19665 ENOG4107QHF type ii secretion system protein e CXL13_19670 ENOG4105D7Q type ii secretion system CXL13_19680 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) CXL13_19700 ENOG4105M6F mutator MutT protein CXL13_19720 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) CXL13_19725 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) CXL13_19730 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) CXL13_19735 ENOG4105CPF Cell wall formation (By similarity) CXL13_19750 ENOG4105CNI cell division protein FtsW CXL13_19765 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) CXL13_19770 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) CXL13_19775 ENOG4105CJN penicillin-binding protein CXL13_19780 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) CXL13_19795 ENOG4107B7Y DNA-binding transcriptional regulator FruR CXL13_19800 ENOG4108ZP8 Acetolactate synthase small subunit CXL13_19805 ENOG4105C7K acetolactate synthase CXL13_19810 ENOG41064T2 transcriptional regulator, lysR family CXL13_19835 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) CXL13_19850 ENOG4105DP9 ABC transporter CXL13_19855 ENOG4106SMU thiamine transporter membrane protein CXL13_19860 ENOG4107T0D ABC, transporter CXL13_19865 ENOG4108KF1 Membrane CXL13_19870 ENOG41063TF transcriptional regulator (AraC CXL13_19875 ENOG4105EF1 ribulokinase CXL13_19885 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase CXL13_19905 ENOG4105CQ2 DNA polymerase CXL13_19920 ENOG4105D3G Pseudouridine synthase CXL13_19930 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) CXL13_19940 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) CXL13_20010 ENOG4105M5B (LipO)protein CXL13_20015 ENOG4105C54 Major Facilitator superfamily CXL13_20020 ENOG4105WQV ferredoxin-like protein CXL13_20025 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase CXL13_20055 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F CXL13_20075 ENOG4108XNW Transcriptional activatory protein CaiF CXL13_20080 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain CXL13_20085 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain CXL13_20115 ENOG4105CHY citrate lyase, alpha CXL13_20120 ENOG4105CI0 Citrate lyase CXL13_20130 ENOG4105DUA (citrate (pro-3S)-lyase ligase CXL13_20145 ENOG4107QSA Oxaloacetate decarboxylase CXL13_20150 ENOG4105D9Q decarboxylase (Beta subunit) CXL13_20155 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism CXL13_20160 ENOG4106YYS transcriptional regulatory protein CXL13_20180 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase CXL13_20190 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) CXL13_20195 ENOG4105DTN riboflavin biosynthesis protein ribF CXL13_20200 ENOG410647N response to DNA damage stimulus CXL13_20220 ENOG41063Z6 transcriptional regulator, lysR family CXL13_20245 ENOG4105C4X radical SAM domain protein CXL13_20250 ENOG41061MV Arylsulfatase CXL13_20285 ENOG4106PH7 chaperone CXL13_20300 ENOG4105MHR Fimbrial protein CXL13_20305 ENOG4105CW0 outer membrane usher protein CXL13_20310 ENOG4108AF8 Chaperone CXL13_20370 ENOG4108QUJ UPF0174 protein YaaW CXL13_20375 ENOG4106HK8 GPR1 FUN34 yaaH family protein CXL13_20380 ENOG4108RIR Molybdenum cofactor biosynthesis protein CXL13_20390 ENOG4105BZG amino acid carrier protein CXL13_20400 ENOG4105D98 threonine synthase CXL13_20410 ENOG4105CFH Aspartokinase CXL13_20420 ENOG4106FVC RNA methyltransferase CXL13_20425 ENOG410759A CXL13_20430 ENOG41065U4 response regulator CXL13_20440 ENOG4108PNB DNA-binding transcriptional regulator CXL13_20450 ENOG4108VCD Chaperone CXL13_20455 ENOG4105CW0 outer membrane usher protein CXL13_20470 ENOG4105CT7 inner membrane cred family protein CXL13_20475 ENOG4105EB3 Histidine kinase CXL13_20480 ENOG4105E3W Two component transcriptional regulator (Winged helix family CXL13_20485 ENOG4108RH0 Crea protein CXL13_20490 ENOG4105UEI Transcriptional Regulator AraC Family CXL13_20515 ENOG4107SC1 transglycosylase CXL13_20525 ENOG4105C5H ABC transporter CXL13_20530 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase CXL13_20535 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) CXL13_20540 ENOG4105EAC phosphoserine phosphatase CXL13_20550 ENOG41062Z9 Membrane CXL13_20565 ENOG4105UMR response to DNA damage stimulus CXL13_20570 ENOG4108S1B Periplasmic chaperone protein CXL13_20575 ENOG4105E6S usher protein( CXL13_20605 ENOG4105G0K glycine radical enzyme YjjI family CXL13_20610 ENOG41076CZ activating enzyme CXL13_20615 ENOG4105EYA deoxyribonuclease CXL13_20620 ENOG4108NRW Phospholipase, patatin family CXL13_20630 ENOG4105K3G Periplasmic Protein CXL13_20640 ENOG4105PAD Hydrolase CXL13_20645 ENOG4105KEG ribosomal-protein-alanine acetyltransferase CXL13_20650 ENOG4108WPU DNA polymerase III subunit psi CXL13_20675 ENOG4105YBH Protein of unknown function (DUF1435) CXL13_20680 ENOG4105BZU Histidine kinase CXL13_20685 ENOG4108819 ferric iron reductase CXL13_20690 ENOG4108UIN ybak prolyl-trna synthetase associated region CXL13_20695 ENOG4108T94 DNA-binding transcriptional activator BglJ CXL13_20700 ENOG4108N8T regulatoR CXL13_20705 ENOG4105DWK Membrane CXL13_20720 ENOG4106CVF DNA replication protein CXL13_20725 ENOG4105RI1 glycoprotein receptor CXL13_20735 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) CXL13_20740 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) CXL13_20745 ENOG4105F3R pts system mannose fructose sorbose family iid CXL13_20750 ENOG4105ETZ PTS System CXL13_20755 ENOG4108IQ3 PTS system CXL13_20770 ENOG4105C8Q Methyl-accepting chemotaxis CXL13_20775 ENOG4105D22 carbon starvation protein CXL13_20780 ENOG4105VCD cytoplasmic protein CXL13_20785 ENOG4105CKI cobalamin synthesis protein CXL13_20795 ENOG4108F3G Type I restriction-modification system, R subunit CXL13_20805 ENOG4107QTH restriction modification system DNA specificity domain CXL13_20820 ENOG4108HFV CXL13_20835 ENOG4105C26 Dehydrogenase CXL13_20840 ENOG4105DNE Transposase CXL13_20845 ENOG41083G8 Multidrug resistance protein MdtM CXL13_20850 ENOG4106BRA Membrane CXL13_20855 ENOG4105CBP Major Facilitator CXL13_20860 ENOG41074DU domain protein CXL13_20865 ENOG4108P2H Inner membrane protein YjiG CXL13_20870 ENOG4105DYB Isoaspartyl dipeptidase CXL13_20875 ENOG4107YNJ LysR family Transcriptional regulator CXL13_20900 ENOG4105C6F GntR Family Transcriptional Regulator CXL13_20925 ENOG4105KZM cytoplasmic protein CXL13_20945 ENOG4105DTA methyltransferase CXL13_20965 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase CXL13_21000 ENOG4105C9U ATP-dependent DNA helicase RecQ CXL13_21005 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) CXL13_21065 ENOG4105DQ4 alcohol dehydrogenase CXL13_21070 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family CXL13_21075 ENOG4105CPQ Dehydrogenase CXL13_21080 ENOG4105CHR reductase CXL13_21085 ENOG4105C6Z Gluconate CXL13_21090 ENOG4105K2J Transcriptional regulator CXL13_21095 ENOG4108K5H permease YjgP YjgQ family protein CXL13_21100 ENOG4108M8S permease YjgP YjgQ family protein CXL13_21120 ENOG4105MYG DNA polymerase iii, chi subunit CXL13_21125 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) CXL13_21130 ENOG4108M3P Membrane CXL13_21135 ENOG4108MJ3 acetyltransferase CXL13_21145 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase CXL13_21150 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) CXL13_21155 ENOG4105DBV ornithine carbamoyltransferase CXL13_21160 ENOG4105XEP YhcH YjgK YiaL family protein CXL13_21175 ENOG4105C5B carbamate kinase CXL13_21180 ENOG4105DBV ornithine carbamoyltransferase CXL13_21185 ENOG4105CSX c4-dicarboxylate anaerobic carrier CXL13_21190 ENOG410682Y Regulates arginine biosynthesis genes (By similarity) CXL13_21200 ENOG41077AM PyrBI operon attenuator CXL13_21215 ENOG4105KME endoribonuclease L-psp CXL13_21230 ENOG4105D4X repressor CXL13_21235 ENOG4105C5Y PTS System CXL13_21240 ENOG4105CG3 alpha amylase, catalytic region CXL13_21245 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase CXL13_21250 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) CXL13_21255 ENOG4105K4U addiction module toxin, RelE StbE family CXL13_21265 ENOG4105EMD TRANSCRIPTIONal CXL13_21280 ENOG41069H0 dihydroorotase EC 3.5.2.3 CXL13_21310 ENOG4108XVM Cytochrome b(562) CXL13_21315 ENOG4105CMS peptidase U62, modulator of DNA gyrase CXL13_21325 ENOG4105F0H myo-inositol catabolism protein CXL13_21335 ENOG4105IE8 Alpha-ketoglutarate permease CXL13_21340 ENOG4105CK5 oxidoreductase CXL13_21345 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) CXL13_21350 ENOG4105D7K pfkb domain protein CXL13_21360 ENOG4107VG4 Xylose isomerase domain protein TIM barrel CXL13_21365 ENOG4108MYR Secreted protein CXL13_21390 ENOG4105C26 Dehydrogenase CXL13_21395 ENOG4105DH8 myo-inositol catabolism CXL13_21400 ENOG4107QNK )-transporter CXL13_21410 ENOG4107QNK )-transporter CXL13_21415 ENOG4105CHC glucokinase (EC 2.7.1.2) CXL13_21425 ENOG4105DFU Cell wall formation (By similarity) CXL13_21435 ENOG4105F0N pyrophosphate phospho-hydrolase CXL13_21440 ENOG41069H0 dihydroorotase EC 3.5.2.3 CXL13_21445 ENOG4105DJB Major Facilitator Superfamily CXL13_21450 ENOG4108ZHD aig2 family CXL13_21470 ENOG4105C37 (CBS) domain CXL13_21475 ENOG41061GZ Protein of unknown function (DUF1107) CXL13_21485 ENOG4108UUE Transcriptional regulator CXL13_21490 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase CXL13_21500 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic CXL13_21505 ENOG4105KVH Transcriptional regulator CXL13_21510 ENOG4105ECR NmrA family CXL13_21515 ENOG4105DXC membrane CXL13_21530 ENOG4108V1T peptidylprolyl cis-trans isomerase CXL13_21540 ENOG4105FHY Opacity-associated protein A CXL13_21555 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) CXL13_21565 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) CXL13_21580 ENOG4105KIT UPF0379 protein yjfY CXL13_21610 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC CXL13_21625 ENOG4108MXZ Esterase CXL13_21630 ENOG4105WSB biofilm stress and motility protein A CXL13_21635 ENOG4105S17 UPF0379 protein yjfN CXL13_21640 ENOG4105CSU acyl-Coa dehydrogenase CXL13_21645 ENOG4106032 Glutathionylspermidine synthase CXL13_21650 ENOG4108KXT Conserved Protein CXL13_21655 ENOG4105Z6B inner membrane protein yjfl CXL13_21660 ENOG4107VNS Protein of unknown function (DUF2491) CXL13_21670 ENOG4108P9J Phage shock protein A CXL13_21675 ENOG4105FUX Conserved Protein CXL13_21680 ENOG4105C2N RNA methyltransferase TrmH family group 3 CXL13_21685 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) CXL13_21710 ENOG4105EPW hflc protein CXL13_21715 ENOG4107QJR hflk protein CXL13_21720 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) CXL13_21740 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase CXL13_21745 ENOG4105K8N protein family UPF0079, ATPase CXL13_21750 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) CXL13_21755 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) CXL13_21775 ENOG4106TNF Periplasmic binding protein CXL13_21795 ENOG4105EGS Mechanosensitive ion channel CXL13_21800 ENOG4106CG8 Inner membrane protein YjeO CXL13_21805 ENOG4107SC7 Inner membrane transporter yjeM CXL13_21815 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) CXL13_21820 ENOG4105E33 succinate dehydrogenase CXL13_21840 ENOG4105KPY Small multidrug resistance protein CXL13_21850 ENOG4106BSU Entericidin B CXL13_21870 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein CXL13_21875 ENOG4105MTB Uncharacterized protein YjeJ CXL13_21880 ENOG4108ZVF (LipO)protein CXL13_21895 ENOG4105DVH amino acid CXL13_21900 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 CXL13_21905 ENOG4108IJ0 Aspartate ammonia-lyase CXL13_21910 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CXL13_21925 ENOG4108SIC Transcriptional regulator CXL13_21955 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CXL13_21990 ENOG4108QDQ Ubiquinol-cytochrome C chaperone CXL13_21995 ENOG4108KZE transcriptional regulator CXL13_22035 ENOG4105SBG acid phosphatase CXL13_22055 ENOG4108Z33 Thiol disulfide Interchange Protein CXL13_22120 ENOG41068CG regulatoR CXL13_22125 ENOG41080WI Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity) CXL13_22135 ENOG4108ZK4 sdia-regulated domain-containing protein CXL13_22145 ENOG4108NEM leader-binding protein dmsD CXL13_22150 ENOG4107KGK dmso reductase anchor subunit CXL13_22155 ENOG4105QAX Iron-sulfur CXL13_22160 ENOG4107QY8 reductase CXL13_22165 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism CXL13_22170 ENOG4108MRH transcriptional regulatory protein CXL13_22180 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CXL13_22185 ENOG4107GFK fumarate CXL13_22190 ENOG4105CT4 transporter CXL13_22195 ENOG4105F8D glycoside hydrolase family 4 CXL13_22200 ENOG4108K2B transcriptional regulator CXL13_22205 ENOG4105CXN decarboxylase CXL13_22210 ENOG4106ZGR Transcriptional regulator CXL13_22215 ENOG4105D5Q Arginine ornithine antiporter CXL13_22220 ENOG4105DIJ Phosphoethanolamine transferase CXL13_22225 ENOG4105XJC Two component transcriptional regulator (Winged helix family CXL13_22230 ENOG4105ECM Sensor protein basS pmrB CXL13_22240 ENOG4105CSH Transporter CXL13_22245 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA CXL13_22250 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase CXL13_22255 ENOG410870W N-acetyltransferase CXL13_22270 ENOG41082ND Uncharacterized protein yjcO CXL13_22275 ENOG4105CK2 sodium dicarboxylate symporter CXL13_22280 ENOG4108W0S formate-dependent nitrite reductase complex CXL13_22285 ENOG4108QKW cytochrome c-type biogenesis protein CXL13_22290 ENOG4105DVI reductase, NrfD CXL13_22295 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein CXL13_22300 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit CXL13_22315 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) CXL13_22320 ENOG41062QD Membrane CXL13_22330 ENOG41067MG lrgb family CXL13_22340 ENOG4105CMU LysR family (Transcriptional regulator CXL13_22345 ENOG4105EEQ Na H antiporter CXL13_22355 ENOG4105C7N Xanthine uracil vitamin C permease CXL13_22370 ENOG4108Z4X TRANSCRIPTIONal CXL13_22375 ENOG4108W3Q Transcriptional regulator CXL13_22380 ENOG4108M8H domain protein CXL13_22385 ENOG4105PMV Membrane CXL13_22420 ENOG4108UUM single-stranded DNA-binding protein CXL13_22430 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) CXL13_22445 ENOG4105MSB protein, conserved in bacteria CXL13_22450 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme CXL13_22455 ENOG4105F0S class B acid phosphatase CXL13_22465 ENOG4105CGF Aromatic amino acid aminotransferase CXL13_22470 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) CXL13_22475 ENOG4105CDU Replicative dna helicase CXL13_22480 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein CXL13_22485 ENOG4105P4Z Phage shock protein G CXL13_22490 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) CXL13_22500 ENOG4105MYN Zinc uptake regulation protein CXL13_22505 ENOG4105VDW Csbd family CXL13_22515 ENOG4107R73 Mate efflux family protein CXL13_22525 ENOG41080IJ Diacylglycerol kinase CXL13_22545 ENOG4107W52 maltose operon periplasmic protein CXL13_22560 ENOG4107FKK extracellular solute-binding protein family 1 CXL13_22565 ENOG4105D56 permease protein CXL13_22570 ENOG4105EG2 ABC transporter, permease CXL13_22580 ENOG4105E3R (LipO)protein CXL13_22585 ENOG4108Q9C Periplasmic Protein CXL13_22590 ENOG4108MDC (LipO)protein CXL13_22605 ENOG4105CFH Aspartokinase CXL13_22690 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) CXL13_22695 ENOG4105CKK Glycosyl transferase, family 2 CXL13_22720 ENOG4108X9F tail fiber protein CXL13_22745 ENOG4105C09 Bile acid CXL13_22750 ENOG4108ZR5 Conserved Protein CXL13_22755 ENOG4105FE9 pseudouridine synthase CXL13_22760 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme CXL13_22775 ENOG4105EAM Na Pi-cotransporter CXL13_22780 ENOG4105C3R Methionine synthase CXL13_22785 ENOG41069M3 Transcriptional regulator CXL13_22800 ENOG4108I9X Isocitrate lyase CXL13_22805 ENOG4107QP3 malate synthase g CXL13_22815 ENOG4105K5X acetyltransferase CXL13_22845 ENOG4105C12 Phosphoribosylglycinamide synthetase CXL13_22850 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CXL13_22855 ENOG4105BZU Histidine kinase CXL13_22865 ENOG4108T8B Protein of unknown function (DUF1481) CXL13_22870 ENOG4105K70 DNA-binding protein CXL13_22875 ENOG4105R2J Conserved Protein CXL13_22910 ENOG4105D06 uba thif-type nad fad binding protein CXL13_22915 ENOG4105WHD thiamine biosynthesis protein ThiS CXL13_22925 ENOG4105D41 biosynthesis protein thiH CXL13_22960 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) CXL13_22985 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) CXL13_22990 ENOG4105PM1 preprotein translocase subunit SecE CXL13_22995 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) CXL13_23035 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase CXL13_23040 ENOG4105D4A Cell wall formation (By similarity) CXL13_23085 ENOG4108Y73 Membrane CXL13_23105 ENOG4105C5Q Transcriptional regulator CXL13_23145 ENOG4105DIJ Phosphoethanolamine transferase CXL13_23150 ENOG4106R3P AraC family transcriptional regulator CXL13_23160 ENOG4105DCT glycerol dehydrogenase CXL13_23165 ENOG4108XC3 NADH ubiquinone oxidoreductase CXL13_23175 ENOG4105SYT Methylenetetrahydrofolate reductase CXL13_23180 ENOG4105CGH 5'-nucleotidase CXL13_23195 ENOG4105D64 Mechanosensitive ion channel CXL13_23200 ENOG4105CFH Aspartokinase CXL13_23205 ENOG4105C28 cystathionine CXL13_23215 ENOG4108MR7 Arylsulfotransferase CXL13_23230 ENOG4105C25 Primosomal protein n' CXL13_23235 ENOG4105ETE Transcriptional regulator (LacI family CXL13_23240 ENOG41063M6 Cell Division Protein CXL13_23255 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase CXL13_23265 ENOG4105N4M Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity) CXL13_23270 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) CXL13_23280 ENOG4105CBT Fructose-1,6-bisphosphatase CXL13_23285 ENOG4105DP0 ferredoxin-NADP reductase CXL13_23290 ENOG4108VTS Membrane CXL13_23295 ENOG4105EBK exported protein CXL13_23320 ENOG4105D4B ABC, transporter CXL13_23345 ENOG4107RYS Autoinducer-2 (AI-2) kinase CXL13_23355 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) CXL13_23375 ENOG4105D7K pfkb domain protein CXL13_23380 ENOG4105CT4 transporter CXL13_23390 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein CXL13_23405 ENOG4105FMW periplasmic CXL13_23410 ENOG4105E3W Two component transcriptional regulator (Winged helix family CXL13_23415 ENOG4105E0F Histidine kinase CXL13_23425 ENOG4108RPX mosc domain containing protein CXL13_23430 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CXL13_23435 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit CXL13_23440 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter CXL13_23445 ENOG4105CG6 trap dicarboxylate transporter dctm subunit CXL13_23450 ENOG4108QGT oligogalacturonate-specific porin CXL13_23480 ENOG4105DKG l-rhamnose isomerase CXL13_23490 ENOG4105C0A alcohol dehydrogenase CXL13_23505 ENOG4108UMN azlc family CXL13_23515 ENOG4108V87 frv operon regulatory protein CXL13_23520 ENOG4108V87 frv operon regulatory protein CXL13_23530 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CXL13_23535 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CXL13_23540 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein CXL13_23545 ENOG4108MG3 formate dehydrogenase CXL13_23560 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system CXL13_23570 ENOG4105RVE Uncharacterized protein conserved in bacteria (DUF2136) CXL13_23575 ENOG4108Z3N Transcriptional regulator CXL13_23580 ENOG4105SUU thioesterase domain CXL13_23595 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 CXL13_23600 ENOG4105E98 transcriptional regulator DeoR family CXL13_23605 ENOG4108MGF sugar kinase CXL13_23610 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase CXL13_23615 ENOG4105D2M Aldolase CXL13_23620 ENOG4107QKS N-acylglucosamine 2-epimerase CXL13_23625 ENOG4107WI4 Aldose-1-epimerase CXL13_23630 ENOG4105CJQ hydrolase, family 31 CXL13_23635 ENOG4105CT4 transporter CXL13_23640 ENOG4105CT4 transporter CXL13_23645 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is CXL13_23675 ENOG4108K4B hydrolase CXL13_23690 ENOG4105C5F glutamine synthetase CXL13_23695 ENOG4105CUX Signal transduction histidine kinase CXL13_23700 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CXL13_23705 ENOG4106FIY CXL13_23710 ENOG4105D4P Coproporphyrinogen iii oxidase CXL13_23730 ENOG4105C2M dna polymerase I CXL13_23740 ENOG4106HNH Acyl-transferase CXL13_23755 ENOG4105PC1 Conserved Protein CXL13_23760 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) CXL13_23765 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b CXL13_23795 ENOG4108RR8 protoporphyrinogen oxidase CXL13_23800 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) CXL13_23805 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein CXL13_23825 ENOG4108MR7 Arylsulfotransferase CXL13_23830 ENOG4107QK7 reductase CXL13_23835 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) CXL13_23840 ENOG4105MDZ Transcriptional activator rfaH CXL13_23845 ENOG4105F8V Hydrolase, tatD family CXL13_23850 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) CXL13_23860 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) CXL13_23870 ENOG4105JC1 sterol-binding domain protein CXL13_23880 ENOG4105CGY Dna recombination protein CXL13_23885 ENOG4108I5U Uridine phosphorylase CXL13_23890 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) CXL13_23895 ENOG4105C4X radical SAM domain protein CXL13_23905 ENOG4105DZ2 Transcriptional regulator CXL13_23910 ENOG4105EMK carboxylate amino acid amine transporter CXL13_23915 ENOG4105DQF Hydrolase CXL13_23920 ENOG4108EUD Lysophospholipase CXL13_23925 ENOG410829K Lysine exporter protein (Lyse ygga) CXL13_23930 ENOG4105CCF Lysine exporter protein (Lyse ygga) CXL13_23935 ENOG4105C9U ATP-dependent DNA helicase RecQ CXL13_23940 ENOG4105HDD phospholipase CXL13_23945 ENOG4108VUY thioesterase Superfamily protein CXL13_23950 ENOG4105FR1 rard protein CXL13_23955 ENOG4106WR8 Inner membrane protein YigG CXL13_23960 ENOG4105NRM Membrane CXL13_23975 ENOG4105C4R Atp-dependent dna helicase CXL13_23980 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant CXL13_23985 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CXL13_23990 ENOG4105CT0 Protein of unknown function, DUF484 CXL13_24000 ENOG4105S7Z (LipO)protein CXL13_24025 ENOG4107T0K Adenylate cyclase CXL13_24035 ENOG41076E6 Uroporphyrinogen-III Synthase CXL13_24040 ENOG4105ECF c-methyltransferase CXL13_24045 ENOG410601J HemY protein CXL13_24070 ENOG4105C85 amino acid CXL13_24085 ENOG4105F18 Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity) CXL13_24090 ENOG4105EGZ biosynthesis protein CXL13_24095 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase CXL13_24100 ENOG4108WJ1 acetyltransferase CXL13_24105 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) CXL13_24110 ENOG4105C1B dTDP-glucose 4-6-dehydratase CXL13_24115 ENOG4108IJ1 Dehydrogenase CXL13_24120 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase CXL13_24125 ENOG4105SFE lipopolysaccharide biosynthesis protein CXL13_24130 ENOG4105ESV Glycosyl transferase, family 4 CXL13_24140 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) CXL13_24150 ENOG4105K63 Thioredoxin CXL13_24170 ENOG4105C4R Atp-dependent dna helicase CXL13_24175 ENOG4106Z1T Nicotinamide Mononucleotide Transporter CXL13_24180 ENOG4107SXA Phosphorylase CXL13_24190 ENOG4105KQ5 peptidylprolyl cis-trans isomerase CXL13_24195 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase CXL13_24200 ENOG4105EMY transcriptional regulator CXL13_24215 ENOG4105C7B Threonine dehydratase CXL13_24225 ENOG4105CM2 brancheD-chain amino acid aminotransferase CXL13_24230 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit CXL13_24245 ENOG4105C0P Mg chelatase subunit ChlI CXL13_24290 ENOG4107EJG GntR family transcriptional regulator CXL13_24295 ENOG4105C0R drug resistance transporter emrb qaca subfamily CXL13_24300 ENOG4105ETE Transcriptional regulator (LacI family CXL13_24305 ENOG4108RVA ribokinase CXL13_24310 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CXL13_24315 ENOG4105CNN ABC, transporter CXL13_24350 ENOG4108VVK transcriptional Regulator, AsnC CXL13_24355 ENOG4105QTB Flavodoxin CXL13_24375 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation CXL13_24385 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) CXL13_24415 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) CXL13_24435 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) CXL13_24440 ENOG4105F9E Shikimate 5-dehydrogenase CXL13_24445 ENOG4105DM4 PTS System CXL13_24450 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) CXL13_24455 ENOG4105C8U phosphate abc transporter CXL13_24460 ENOG4105E2Z phosphate ABC transporter (Permease CXL13_24475 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 CXL13_24485 ENOG4105C7N Xanthine uracil vitamin C permease CXL13_24490 ENOG4108YYH Nadph-dependent fmn reductase CXL13_24495 ENOG4105E8Q phosphopantetheinyl transferase CXL13_24530 ENOG4105DFP Integrase