locus-tag	class	description
CA266_00005	COG0833	amino acid
CA266_00010	COG2040	homocysteine
CA266_00055	COG0583	DNA-binding transcription factor activity
CA266_00060	COG3397	chitin binding
CA266_00075	COG2376	Dihydroxyacetone kinase
CA266_00080	COG1028	Short-chain dehydrogenase reductase Sdr
CA266_00085	COG2814	Major facilitator Superfamily
CA266_00090	COG1063	alcohol dehydrogenase
CA266_00095	COG0698	ribose 5-phosphate isomerase
CA266_00100	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CA266_00105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CA266_00110	COG0494	nUDIX hydrolase
CA266_00115	COG3850	Histidine kinase
CA266_00120	COG2197	response regulator
CA266_00130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CA266_00150	COG0454	-acetyltransferase
CA266_00160	COG1393	Belongs to the ArsC family
CA266_00165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CA266_00170	COG1876	peptidase activity
CA266_00180	COG0400	carboxylic ester hydrolase activity
CA266_00190	COG2321	neutral zinc metallopeptidase
CA266_00195	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CA266_00200	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CA266_00205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CA266_00210	COG2716	regulation of RNA biosynthetic process
CA266_00215	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CA266_00220	COG0628	permease
CA266_00265	COG4783	chaperone-mediated protein folding
CA266_00270	COG1393	Belongs to the ArsC family
CA266_00275	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CA266_00285	COG2261	transglycosylase associated protein
CA266_00290	COG2233	PERMEase
CA266_00295	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CA266_00300	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CA266_00305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CA266_00310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CA266_00330	COG0573	inorganic phosphate transmembrane transporter activity
CA266_00335	COG0573	inorganic phosphate transmembrane transporter activity
CA266_00340	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CA266_00355	COG2239	Acts as a magnesium transporter
CA266_00360	COG3447	MASE1 domain protein
CA266_00360	COG5002	protein histidine kinase activity
CA266_00360	COG5001	Diguanylate cyclase
CA266_00375	COG0443	Heat shock 70 kDa protein
CA266_00390	COG0667	Aldo Keto reductase
CA266_00395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CA266_00400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CA266_00405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CA266_00410	COG2814	Major facilitator Superfamily
CA266_00415	COG2205	protein histidine kinase activity
CA266_00420	COG0745	RESPONSE REGULATOR receiver
CA266_00435	COG3422	double-strand break repair
CA266_00440	COG0826	peptidase U32
CA266_00450	COG1597	lipid kinase activity
CA266_00460	COG1063	alcohol dehydrogenase
CA266_00465	COG2271	Major facilitator Superfamily
CA266_00470	COG0246	Mannitol dehydrogenase
CA266_00480	COG1802	Transcriptional regulator
CA266_00485	COG1830	Aldolase
CA266_00490	COG3730	PTS system glucitol sorbitol-specific
CA266_00505	COG1028	Short-chain dehydrogenase reductase Sdr
CA266_00510	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CA266_00515	COG1349	DNA-binding transcription factor activity
CA266_00530	COG0351	phosphomethylpyrimidine kinase
CA266_00535	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CA266_00555	COG1289	transmembrane transporter activity
CA266_00565	COG2814	Major facilitator Superfamily
CA266_00585	COG1187	pseudouridine synthase activity
CA266_00605	COG5002	protein histidine kinase activity
CA266_00605	COG2205	protein histidine kinase activity
CA266_00605	COG0784	Response regulator, receiver
CA266_00615	COG1733	regulation of RNA biosynthetic process
CA266_00640	COG0519	Catalyzes the synthesis of GMP from XMP
CA266_00640	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CA266_00645	COG0517	IMP dehydrogenase activity
CA266_00645	COG0516	GMP reductase activity
CA266_00650	COG1570	exodeoxyribonuclease VII activity
CA266_00660	COG2271	Major facilitator Superfamily
CA266_00665	COG1609	Transcriptional regulator
CA266_00680	COG1645	bacterial-type flagellum-dependent swarming motility
CA266_00690	COG1160	GTP binding
CA266_00695	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CA266_00700	COG2976	Protein conserved in bacteria
CA266_00705	COG0124	histidyl-tRNA synthetase
CA266_00710	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CA266_00715	COG1426	Protein conserved in bacteria
CA266_00725	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CA266_00730	COG0105	UTP biosynthetic process
CA266_00740	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CA266_00745	COG2975	iron-sulfur cluster assembly
CA266_00750	COG0633	Ferredoxin
CA266_00755	COG0443	Heat shock 70 kDa protein
CA266_00760	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CA266_00765	COG0316	Belongs to the HesB IscA family
CA266_00770	COG0822	iron-sulfur transferase activity
CA266_00775	COG1104	cysteine desulfurase activity
CA266_00780	COG1959	2 iron, 2 sulfur cluster binding
CA266_00795	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CA266_00800	COG3683	transport system, periplasmic component
CA266_00805	COG3711	transcriptional antiterminator
CA266_00810	COG2814	Major facilitator Superfamily
CA266_00815	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CA266_00820	COG1017	nitric oxide dioxygenase activity
CA266_00820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CA266_00830	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CA266_00835	COG1012	belongs to the aldehyde dehydrogenase family
CA266_00840	COG1177	transmembrane transport
CA266_00845	COG1176	ABC-type spermidine putrescine transport system, permease component I
CA266_00850	COG3842	ATPase activity
CA266_00855	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CA266_00865	COG0583	DNA-binding transcription factor activity
CA266_00870	COG0347	Belongs to the P(II) protein family
CA266_00875	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CA266_00875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CA266_00880	COG2204	response regulator
CA266_00885	COG3170	Tfp pilus assembly protein FimV
CA266_00890	COG2205	protein histidine kinase activity
CA266_00900	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CA266_00915	COG0560	Phosphoserine phosphatase
CA266_00920	COG1263	PTS System
CA266_00920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CA266_00925	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CA266_00930	COG1737	Transcriptional regulator
CA266_00935	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CA266_00940	COG0736	holo-[acyl-carrier-protein] synthase activity
CA266_00945	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CA266_00950	COG1381	Involved in DNA repair and RecF pathway recombination
CA266_00955	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CA266_00960	COG0571	ribonuclease III activity
CA266_00970	COG0481	GTPase activity
CA266_00980	COG3086	response to oxidative stress
CA266_00985	COG3026	antisigma factor binding
CA266_01000	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CA266_01005	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CA266_01010	COG0513	Belongs to the DEAD box helicase family
CA266_01030	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CA266_01035	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CA266_01040	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CA266_01045	COG0497	DNA recombination
CA266_01050	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CA266_01055	COG2914	Belongs to the UPF0125 (RnfH) family
CA266_01060	COG2867	negative regulation of translational initiation
CA266_01065	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CA266_01075	COG1566	PFAM secretion protein HlyD family protein
CA266_01090	COG0583	DNA-binding transcription factor activity
CA266_01095	COG3182	Iron-regulated membrane protein
CA266_01105	COG0454	-acetyltransferase
CA266_01130	COG2388	GCN5-related N-acetyl-transferase
CA266_01135	COG3592	Divergent 4Fe-4S mono-cluster
CA266_01140	COG2259	Doxx family
CA266_01145	COG2840	Smr protein MutS2
CA266_01165	COG0477	Major facilitator Superfamily
CA266_01175	COG0477	Major facilitator Superfamily
CA266_01190	COG4575	ribosome binding
CA266_01195	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CA266_01200	COG1780	Probably involved in ribonucleotide reductase function
CA266_01230	COG1028	Short-chain dehydrogenase reductase Sdr
CA266_01240	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CA266_01245	COG1752	Esterase of the alpha-beta hydrolase superfamily
CA266_01250	COG3493	citrate carrier protein
CA266_01275	COG4176	ABC-type proline glycine betaine transport system permease component
CA266_01280	COG2113	Glycine betaine
CA266_01285	COG0583	DNA-binding transcription factor activity
CA266_01290	COG2814	Major facilitator Superfamily
CA266_01295	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CA266_01305	COG1846	Transcriptional regulator
CA266_01315	COG1566	PFAM secretion protein HlyD family protein
CA266_01320	COG2814	Major facilitator Superfamily
CA266_01325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CA266_01330	COG3118	belongs to the thioredoxin family
CA266_01335	COG3148	PFAM DTW domain containing protein
CA266_01345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CA266_01350	COG0477	Major facilitator Superfamily
CA266_01380	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CA266_01390	COG2011	ABC-type metal ion transport system permease component
CA266_01405	COG1720	tRNA m6t6A37 methyltransferase activity
CA266_01410	COG0442	prolyl-tRNA aminoacylation
CA266_01415	COG3015	lipoprotein NlpE involved in copper resistance
CA266_01420	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CA266_01435	COG4568	rho-dependent transcription termination
CA266_01445	COG0037	tRNA processing
CA266_01450	COG3104	oligopeptide transport
CA266_01460	COG0531	amino acid
CA266_01465	COG3710	Transcriptional regulator
CA266_01470	COG0346	lactoylglutathione lyase activity
CA266_01475	COG1982	Orn Lys Arg decarboxylase major
CA266_01480	COG0825	malonyl-CoA metabolic process
CA266_01490	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CA266_01495	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CA266_01500	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CA266_01505	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CA266_01510	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CA266_01515	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CA266_01520	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CA266_01525	COG0750	zinc metalloprotease
CA266_01530	COG0575	Belongs to the CDS family
CA266_01535	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CA266_01540	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CA266_01545	COG0233	cytoplasmic translational termination
CA266_01550	COG0528	UMP kinase activity
CA266_01560	COG0052	Belongs to the universal ribosomal protein uS2 family
CA266_01570	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CA266_01590	COG0564	pseudouridine synthase activity
CA266_01595	COG4953	penicillin-binding protein 1C
CA266_01600	COG2373	Large extracellular alpha-helical protein
CA266_01605	COG3098	single-species biofilm formation
CA266_01610	COG2814	Major facilitator Superfamily
CA266_01625	COG1611	Belongs to the LOG family
CA266_01630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CA266_01635	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CA266_01640	COG2363	Small membrane protein
CA266_01645	COG0583	DNA-binding transcription factor activity
CA266_01655	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CA266_01660	COG2166	iron-sulfur cluster assembly
CA266_01665	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CA266_01670	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CA266_01690	COG0860	N-Acetylmuramoyl-L-alanine amidase
CA266_01695	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CA266_01695	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CA266_01700	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CA266_01705	COG1074	ATP-dependent DNA helicase activity
CA266_01710	COG1025	Belongs to the peptidase M16 family
CA266_01715	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CA266_01735	COG2165	general secretion pathway protein
CA266_01740	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CA266_01745	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CA266_01755	COG0494	nUDIX hydrolase
CA266_01760	COG3066	DNA modification
CA266_01765	COG0861	Integral membrane protein TerC family
CA266_01775	COG0667	Aldo Keto reductase
CA266_01780	COG0477	Major facilitator Superfamily
CA266_01785	COG0204	Acyl-transferase
CA266_01785	COG0318	PFAM AMP-dependent synthetase and ligase
CA266_01795	COG1609	Transcriptional regulator
CA266_01805	COG0583	DNA-binding transcription factor activity
CA266_01810	COG0583	DNA-binding transcription factor activity
CA266_01830	COG4178	(ABC) transporter
CA266_01840	COG3716	PTS system mannose fructose sorbose family IID component
CA266_01845	COG3715	PTS system
CA266_01850	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CA266_01860	COG1349	DNA-binding transcription factor activity
CA266_01865	COG2807	transmembrane transport
CA266_01875	COG4615	Cyclic peptide transporter
CA266_01880	COG0583	DNA-binding transcription factor activity
CA266_01885	COG1620	l-lactate permease
CA266_01890	COG1304	FMN binding
CA266_01900	COG2814	Major facilitator Superfamily
CA266_01915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CA266_01920	COG1309	transcriptional regulator
CA266_01925	COG5265	(ABC) transporter
CA266_01930	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CA266_01935	COG4942	peptidase
CA266_01940	COG1335	isochorismatase
CA266_01945	COG0583	DNA-binding transcription factor activity
CA266_01950	COG3247	response to pH
CA266_01975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CA266_01980	COG1609	Transcriptional regulator
CA266_02000	COG2731	YhcH YjgK YiaL family protein
CA266_02005	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CA266_02010	COG2271	Major facilitator Superfamily
CA266_02020	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CA266_02030	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CA266_02035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CA266_02040	COG4974	Belongs to the 'phage' integrase family
CA266_02045	COG0716	FMN binding
CA266_02050	COG4452	Inner membrane protein CreD
CA266_02055	COG2205	protein histidine kinase activity
CA266_02060	COG0745	RESPONSE REGULATOR receiver
CA266_02070	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CA266_02075	COG0354	folic acid binding
CA266_02085	COG1272	protein, Hemolysin III
CA266_02095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CA266_02100	COG1940	carbohydrate kinase activity
CA266_02105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CA266_02115	COG1172	Belongs to the binding-protein-dependent transport system permease family
CA266_02120	COG1129	ABC transporter
CA266_02130	COG1349	DNA-binding transcription factor activity
CA266_02145	COG0154	amidase activity
CA266_02170	COG1028	Short-chain dehydrogenase reductase Sdr
CA266_02200	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CA266_02200	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CA266_02205	COG0509	glycine decarboxylation via glycine cleavage system
CA266_02210	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CA266_02215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CA266_02220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CA266_02225	COG0006	proline dipeptidase activity
CA266_02230	COG3079	Belongs to the UPF0149 family
CA266_02235	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CA266_02245	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CA266_02250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CA266_02260	COG0583	DNA-binding transcription factor activity
CA266_02270	COG1279	arginine transmembrane transporter activity
CA266_02275	COG1414	Transcriptional regulator
CA266_02280	COG1129	ABC transporter
CA266_02285	COG1172	Belongs to the binding-protein-dependent transport system permease family
CA266_02305	COG2731	YhcH YjgK YiaL family protein
CA266_02315	COG1070	Carbohydrate kinase
CA266_02320	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CA266_02325	COG3623	hexulose-6-phosphate isomerase
CA266_02330	COG0235	Class ii aldolase
CA266_02340	COG3122	Protein conserved in bacteria
CA266_02355	COG2271	Major facilitator Superfamily
CA266_02370	COG0191	fructose-bisphosphate aldolase activity
CA266_02375	COG0126	phosphoglycerate kinase activity
CA266_02380	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CA266_02385	COG3842	ATPase activity
CA266_02390	COG1175	transmembrane transport
CA266_02405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CA266_02420	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CA266_02425	COG0501	Belongs to the peptidase M48B family
CA266_02440	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CA266_02445	COG1028	Short-chain dehydrogenase reductase Sdr
CA266_02450	COG2267	carboxylic ester hydrolase activity
CA266_02475	COG1414	Transcriptional regulator
CA266_02480	COG1028	Short-chain dehydrogenase reductase Sdr
CA266_02495	COG2146	nitrite reductase [NAD(P)H] activity
CA266_02500	COG2271	Major facilitator Superfamily
CA266_02510	COG0010	Belongs to the arginase family
CA266_02515	COG3539	Fimbrial protein
CA266_02530	COG3539	Fimbrial protein
CA266_02535	COG3539	Fimbrial protein
CA266_02550	COG3121	Chaperone
CA266_02560	COG1166	arginine decarboxylase activity
CA266_02570	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CA266_02580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CA266_02585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CA266_02590	COG1120	ATPase activity
CA266_02595	COG4774	siderophore transport
CA266_02600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CA266_02605	COG1643	Atp-dependent helicase
CA266_02610	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CA266_02615	COG1489	DNA binding
CA266_02625	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CA266_02630	COG0617	tRNA 3'-terminal CCA addition
CA266_02635	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CA266_02640	COG0642	Histidine kinase
CA266_02650	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CA266_02655	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CA266_02660	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CA266_02665	COG0726	polysaccharide deacetylase
CA266_02670	COG0842	Transport permease protein
CA266_02675	COG1131	(ABC) transporter
CA266_02680	COG0288	reversible hydration of carbon dioxide
CA266_02700	COG2132	Multicopper oxidase
CA266_02710	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CA266_02715	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CA266_02720	COG3112	Uncharacterised protein family (UPF0231)
CA266_02730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CA266_02735	COG0508	dehydrogenase complex catalyzes the overall conversion of
CA266_02740	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CA266_02745	COG2186	Transcriptional regulator
CA266_02750	COG1113	amino acid transport
CA266_02755	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CA266_02755	COG2010	Cytochrome c
CA266_02765	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CA266_02765	COG2010	Cytochrome c
CA266_02775	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CA266_02780	COG2207	Transcriptional regulator
CA266_02780	COG3708	Transcriptional regulator
CA266_02790	COG3091	SprT-like family
CA266_02795	COG2356	endonuclease I
CA266_02800	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CA266_02805	COG0189	ligase activity
CA266_02810	COG1678	Uncharacterized ACR, COG1678
CA266_02815	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CA266_02820	COG2805	Type II/IV secretion system protein
CA266_02825	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CA266_02830	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CA266_02835	COG0762	integral membrane protein
CA266_02840	COG1872	DUF167
CA266_02850	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CA266_02865	COG2066	Belongs to the glutaminase family
CA266_02870	COG3171	Protein conserved in bacteria
CA266_02875	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CA266_02885	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CA266_02890	COG0741	lytic transglycosylase activity
CA266_02895	COG1982	Orn Lys Arg decarboxylase major
CA266_02930	COG2819	hydrolase of the alpha beta superfamily
CA266_02935	COG0454	-acetyltransferase
CA266_02960	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CA266_02960	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CA266_02975	COG4772	TonB-dependent receptor
CA266_02980	COG0583	DNA-binding transcription factor activity
CA266_02985	COG1473	amidohydrolase
CA266_02990	COG1473	amidohydrolase
CA266_02995	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CA266_03025	COG0848	biopolymer transport protein
CA266_03040	COG0586	Pfam SNARE associated Golgi protein
CA266_03045	COG0583	DNA-binding transcription factor activity
CA266_03050	COG0604	alcohol dehydrogenase
CA266_03050	COG1028	Short-chain dehydrogenase reductase Sdr
CA266_03050	COG3321	synthase
CA266_03055	COG2207	Transcriptional regulator
CA266_03060	COG1979	alcohol dehydrogenase
CA266_03065	COG0656	L-ascorbic acid biosynthetic process
CA266_03090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CA266_03095	COG2211	Major facilitator Superfamily
CA266_03100	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CA266_03105	COG0583	DNA-binding transcription factor activity
CA266_03110	COG2132	Multicopper oxidase
CA266_03115	COG0204	Acyl-transferase
CA266_03120	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CA266_03125	COG2249	NAD(P)H dehydrogenase (quinone) activity
CA266_03130	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CA266_03135	COG0583	DNA-binding transcription factor activity
CA266_03140	COG0187	DNA topoisomerase II activity
CA266_03145	COG3150	esterase
CA266_03150	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CA266_03155	COG3151	Protein conserved in bacteria
CA266_03160	COG0494	nUDIX hydrolase
CA266_03165	COG1538	Outer membrane efflux protein
CA266_03175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CA266_03175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CA266_03175	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CA266_03180	COG1461	Dihydroxyacetone kinase
CA266_03185	COG2376	Dihydroxyacetone kinase
CA266_03195	COG5463	Belongs to the UPF0441 family
CA266_03200	COG0754	glutathionylspermidine amidase activity
CA266_03205	COG3384	dioxygenase
CA266_03210	COG1785	Belongs to the alkaline phosphatase family
CA266_03215	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CA266_03225	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CA266_03225	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CA266_03230	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CA266_03235	COG3025	triphosphatase activity
CA266_03240	COG4991	sh3 domain protein
CA266_03245	COG0617	tRNA 3'-terminal CCA addition
CA266_03250	COG1968	undecaprenyl-diphosphatase activity
CA266_03255	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CA266_03260	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CA266_03265	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CA266_03270	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CA266_03275	COG0358	DNA primase activity
CA266_03330	COG0625	glutathione transferase activity
CA266_03340	COG1012	belongs to the aldehyde dehydrogenase family
CA266_03345	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CA266_03355	COG0488	(ABC) transporter
CA266_03360	COG1902	pentaerythritol trinitrate reductase activity
CA266_03360	COG0446	pyridine nucleotide-disulphide oxidoreductase
CA266_03365	COG2813	Specifically methylates the guanine in position
CA266_03370	COG3549	Plasmid maintenance system killer
CA266_03375	COG3093	addiction module antidote protein HigA
CA266_03380	COG1451	nucleotide metabolic process
CA266_03385	COG0673	inositol 2-dehydrogenase activity
CA266_03390	COG0519	Catalyzes the synthesis of GMP from XMP
CA266_03390	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CA266_03395	COG0861	Integral membrane protein TerC family
CA266_03400	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CA266_03405	COG2721	sulfolactate sulfo-lyase activity
CA266_03410	COG1904	glucuronate isomerase
CA266_03415	COG2271	Major facilitator Superfamily
CA266_03430	COG0586	Pfam SNARE associated Golgi protein
CA266_03435	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CA266_03445	COG4575	ribosome binding
CA266_03450	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CA266_03460	COG2259	Doxx family
CA266_03465	COG0435	Glutathione S-transferase
CA266_03470	COG0583	DNA-binding transcription factor activity
CA266_03475	COG1741	Belongs to the pirin family
CA266_03485	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CA266_03490	COG3107	peptidoglycan biosynthetic process
CA266_03495	COG0792	nuclease activity
CA266_03500	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CA266_03505	COG2823	Periplasmic or secreted lipoprotein
CA266_03515	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CA266_03520	COG2198	Histidine kinase
CA266_03520	COG5002	protein histidine kinase activity
CA266_03520	COG0784	Response regulator, receiver
CA266_03525	COG1242	4 iron, 4 sulfur cluster binding
CA266_03530	COG0070	glutamate synthase
CA266_03530	COG0067	glutamate synthase
CA266_03530	COG0069	glutamate synthase activity
CA266_03535	COG0493	'glutamate synthase
CA266_03545	COG2969	positive regulation of protein catabolic process
CA266_03550	COG0625	glutathione transferase activity
CA266_03555	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CA266_03560	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CA266_03565	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CA266_03570	COG3105	Protein conserved in bacteria
CA266_03575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CA266_03580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CA266_03585	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CA266_03590	COG5007	Belongs to the BolA IbaG family
CA266_03595	COG3113	response to antibiotic
CA266_03600	COG2854	intermembrane phospholipid transfer
CA266_03605	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CA266_03610	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CA266_03615	COG1127	ABC transporter
CA266_03620	COG0530	calcium, potassium:sodium antiporter activity
CA266_03625	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CA266_03625	COG0517	IMP dehydrogenase activity
CA266_03630	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CA266_03635	COG3117	lipopolysaccharide transmembrane transporter activity
CA266_03640	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CA266_03645	COG1137	ATPase activity
CA266_03650	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CA266_03665	COG1660	Displays ATPase and GTPase activities
CA266_03670	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CA266_03675	COG3711	transcriptional antiterminator
CA266_03675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CA266_03695	COG3964	amidohydrolase
CA266_03725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CA266_03735	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CA266_03745	COG2207	Transcriptional regulator
CA266_03750	COG3783	Cytochrome b(562)
CA266_03755	COG0312	modulator of DNA gyrase
CA266_03770	COG3028	Belongs to the UPF0307 family
CA266_03775	COG2732	(Barnase) inhibitor
CA266_03785	COG1289	transmembrane transporter activity
CA266_03790	COG1566	PFAM secretion protein HlyD family protein
CA266_03800	COG0583	DNA-binding transcription factor activity
CA266_03825	COG2134	cdp-diacylglycerol pyrophosphatase
CA266_03830	COG0312	modulator of DNA gyrase
CA266_03835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CA266_03840	COG3164	Protein of unknown function
CA266_03845	COG1530	ribonuclease E activity
CA266_03850	COG0424	maF-like protein
CA266_03855	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CA266_03860	COG1792	Involved in formation and maintenance of cell shape
CA266_03865	COG1077	Cell shape determining protein MreB Mrl
CA266_03870	COG2200	EAL domain
CA266_03870	COG2199	diguanylate cyclase activity
CA266_03875	COG0604	alcohol dehydrogenase
CA266_03880	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CA266_03885	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CA266_03890	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CA266_03895	COG0511	ligase activity, forming carbon-carbon bonds
CA266_03900	COG0439	Biotin carboxylase
CA266_03910	COG0039	L-malate dehydrogenase activity
CA266_03920	COG2211	Major facilitator Superfamily
CA266_03930	COG3924	membrane
CA266_03935	COG4145	pantothenate transmembrane transporter activity
CA266_03940	COG2264	protein methyltransferase activity
CA266_03970	COG1560	Kdo2-lipid A biosynthetic process
CA266_03980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CA266_03990	COG1380	Effector of murein hydrolase LrgA
CA266_03995	COG0583	DNA-binding transcription factor activity
CA266_04000	COG0025	NhaP-type Na H and K H
CA266_04005	COG2252	PERMEase
CA266_04015	COG0625	glutathione transferase activity
CA266_04030	COG0583	DNA-binding transcription factor activity
CA266_04035	COG1028	Short-chain dehydrogenase reductase Sdr
CA266_04060	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CA266_04065	COG1064	alcohol dehydrogenase
CA266_04070	COG0110	maltose O-acetyltransferase activity
CA266_04075	COG2315	Protein conserved in bacteria
CA266_04085	COG1448	Aminotransferase
CA266_04090	COG1522	sequence-specific DNA binding
CA266_04110	COG0604	alcohol dehydrogenase
CA266_04120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CA266_04140	COG0735	belongs to the Fur family
CA266_04145	COG3237	CsbD-like
CA266_04150	COG0534	Mate efflux family protein
CA266_04155	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CA266_04160	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CA266_04165	COG2937	Belongs to the GPAT DAPAT family
CA266_04170	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CA266_04175	COG3161	chorismate lyase activity
CA266_04180	COG0477	Major facilitator Superfamily
CA266_04185	COG1609	Transcriptional regulator
CA266_04200	COG4580	involved in the transport of maltose and maltodextrins
CA266_04210	COG0366	Alpha amylase catalytic
CA266_04215	COG2182	Extracellular solute-binding protein
CA266_04220	COG1175	transmembrane transport
CA266_04225	COG3833	ABC-type maltose transport systems, permease component
CA266_04230	COG3223	Belongs to the PsiE family
CA266_04240	COG0166	Belongs to the GPI family
CA266_04250	COG0527	aspartate kinase activity
CA266_04270	COG1283	sodium-dependent phosphate transmembrane transporter activity
CA266_04285	COG0395	ABC-type sugar transport system, permease component
CA266_04290	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CA266_04300	COG2188	Transcriptional regulator
CA266_04305	COG1410	methionine synthase
CA266_04305	COG0646	methionine synthase
CA266_04310	COG1414	Transcriptional regulator
CA266_04315	COG3265	gluconokinase activity
CA266_04320	COG2610	gluconate transmembrane transporter activity
CA266_04325	COG0129	dihydroxy-acid dehydratase activity
CA266_04330	COG0800	Aldolase
CA266_04335	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CA266_04345	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CA266_04350	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CA266_04385	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CA266_04390	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CA266_04395	COG0009	L-threonylcarbamoyladenylate synthase
CA266_04400	COG0551	DNA topoisomerase type I activity
CA266_04405	COG2922	Belongs to the Smg family
CA266_04410	COG0758	DNA mediated transformation
CA266_04415	COG0242	peptide deformylase activity
CA266_04420	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CA266_04425	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CA266_04425	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CA266_04430	COG0569	domain protein
CA266_04435	COG1970	mechanosensitive ion channel activity
CA266_04440	COG3036	rescue of stalled ribosome
CA266_04445	COG0789	Transcriptional regulator
CA266_04455	COG0203	ribosomal protein L17
CA266_04460	COG0202	RNA polymerase activity
CA266_04465	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CA266_04470	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CA266_04475	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CA266_04480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CA266_04485	COG0201	protein transport
CA266_04495	COG1841	ribosomal large subunit assembly
CA266_04500	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CA266_04505	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CA266_04510	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CA266_04550	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CA266_04555	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CA266_04565	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CA266_04575	COG0089	rRNA binding
CA266_04580	COG0088	Forms part of the polypeptide exit tunnel
CA266_04585	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CA266_04590	COG0051	transcription antitermination factor activity, RNA binding
CA266_04605	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CA266_04615	COG0049	tRNA binding
CA266_04620	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CA266_04625	COG2168	tRNA wobble position uridine thiolation
CA266_04630	COG2923	Belongs to the DsrF TusC family
CA266_04635	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CA266_04640	COG2964	Protein conserved in bacteria
CA266_04645	COG0545	Peptidyl-prolyl cis-trans isomerase
CA266_04650	COG2900	Belongs to the SlyX family
CA266_04655	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CA266_04660	COG1757	Na H antiporter
CA266_04665	COG1609	Transcriptional regulator
CA266_04670	COG1047	Peptidyl-prolyl cis-trans
CA266_04675	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CA266_04685	COG2249	NAD(P)H dehydrogenase (quinone) activity
CA266_04690	COG0488	(ABC) transporter
CA266_04695	COG2175	clavaminate synthase activity
CA266_04700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CA266_04710	COG4521	taurine ABC transporter
CA266_04725	COG0429	hydrolase of the alpha beta-hydrolase fold
CA266_04730	COG3089	Belongs to the UPF0270 family
CA266_04735	COG3954	Phosphoribulokinase
CA266_04740	COG1765	OsmC-like protein
CA266_04745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CA266_04750	COG1289	transmembrane transporter activity
CA266_04765	COG0433	COG0433 Predicted ATPase
CA266_04775	COG3275	phosphorelay sensor kinase activity
CA266_04780	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CA266_04785	COG1447	Phosphotransferase system cellobiose-specific component IIA
CA266_04790	COG1486	melibiose metabolic process
CA266_04795	COG1609	Transcriptional regulator
CA266_04800	COG0738	Major facilitator superfamily
CA266_04805	COG2336	PFAM SpoVT AbrB
CA266_04810	COG2337	Toxic component of a toxin-antitoxin (TA) module
CA266_04815	COG0402	S-adenosylhomocysteine deaminase activity
CA266_04820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CA266_04830	COG2116	formate transmembrane transporter activity
CA266_04835	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CA266_04835	COG1648	precorrin-2 dehydrogenase activity
CA266_04840	COG0180	Tryptophanyl-tRNA synthetase
CA266_04845	COG0546	phosphoglycolate phosphatase activity
CA266_04865	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CA266_04870	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CA266_04875	COG4796	Type ii and iii secretion system protein
CA266_04900	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CA266_04905	COG0494	nUDIX hydrolase
CA266_04915	COG1011	Hydrolase
CA266_04920	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CA266_04925	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CA266_04960	COG0484	heat shock protein binding
CA266_04965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CA266_04970	COG2183	response to ionizing radiation
CA266_04975	COG1918	ferrous iron import across plasma membrane
CA266_05000	COG1040	competence protein
CA266_05005	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CA266_05005	COG0316	Belongs to the HesB IscA family
CA266_05010	COG1640	4-alpha-glucanotransferase
CA266_05020	COG2909	trisaccharide binding
CA266_05025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CA266_05030	COG0705	Rhomboid family
CA266_05035	COG1349	DNA-binding transcription factor activity
CA266_05040	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CA266_05045	COG0058	SHG alpha-glucan phosphorylase activity
CA266_05050	COG0297	glycogen (starch) synthase activity
CA266_05055	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CA266_05060	COG1523	belongs to the glycosyl hydrolase 13 family
CA266_05065	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CA266_05070	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CA266_05075	COG2095	MarC family integral membrane protein
CA266_05080	COG3265	gluconokinase activity
CA266_05085	COG2610	gluconate transmembrane transporter activity
CA266_05090	COG1609	Transcriptional regulator
CA266_05095	COG1741	Belongs to the pirin family
CA266_05100	COG1247	-acetyltransferase
CA266_05105	COG3191	aminopeptidase activity
CA266_05110	COG1082	Xylose isomerase domain protein TIM barrel
CA266_05115	COG1082	Xylose isomerase domain protein TIM barrel
CA266_05120	COG0673	inositol 2-dehydrogenase activity
CA266_05125	COG3962	Belongs to the TPP enzyme family
CA266_05130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CA266_05150	COG3718	enzyme involved in inositol metabolism
CA266_05160	COG0477	Major facilitator Superfamily
CA266_05160	COG2814	Major facilitator Superfamily
CA266_05170	COG0390	transport system, permease component
CA266_05175	COG4619	ABC transporter
CA266_05205	COG3188	usher protein
CA266_05230	COG2197	response regulator
CA266_05240	COG0697	spore germination
CA266_05260	COG0583	DNA-binding transcription factor activity
CA266_05270	COG1028	Short-chain dehydrogenase reductase Sdr
CA266_05300	COG2081	HI0933 family
CA266_05305	COG0306	phosphate transporter
CA266_05320	COG0583	DNA-binding transcription factor activity
CA266_05325	COG0589	response to stress
CA266_05340	COG1129	ABC transporter
CA266_05345	COG1172	Belongs to the binding-protein-dependent transport system permease family
CA266_05350	COG1172	Belongs to the binding-protein-dependent transport system permease family
CA266_05365	COG0742	ribosomal rna small subunit methyltransferase
CA266_05370	COG0339	signal peptide processing
CA266_05385	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CA266_05390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CA266_05395	COG2318	DinB family
CA266_05410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CA266_05420	COG0784	Response regulator, receiver
CA266_05420	COG2205	protein histidine kinase activity
CA266_05445	COG5441	Belongs to the UPF0261 family
CA266_05450	COG3678	ATP-independent chaperone mediated protein folding
CA266_05455	COG5001	Diguanylate cyclase
CA266_05460	COG1024	Enoyl-CoA hydratase
CA266_05465	COG1295	ribonuclease BN
CA266_05470	COG0477	Major facilitator Superfamily
CA266_05475	COG2134	cdp-diacylglycerol pyrophosphatase
CA266_05480	COG2982	Protein involved in outer membrane biogenesis
CA266_05485	COG2200	EAL domain
CA266_05490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CA266_05500	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CA266_05525	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CA266_05530	COG0129	dihydroxy-acid dehydratase activity
CA266_05535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CA266_05540	COG3978	acetolactate synthase activity
CA266_05555	COG2814	Major facilitator Superfamily
CA266_05565	COG3085	chromosome segregation
CA266_05570	COG0583	DNA-binding transcription factor activity
CA266_05610	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CA266_05615	COG4206	TonB-dependent receptor
CA266_05620	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CA266_05635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CA266_05645	COG0678	peroxiredoxin activity
CA266_05645	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CA266_05650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CA266_05660	COG0165	Argininosuccinate lyase
CA266_05665	COG0137	argininosuccinate synthase activity
CA266_05670	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CA266_05685	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CA266_05695	COG0527	aspartate kinase activity
CA266_05695	COG0460	homoserine dehydrogenase
CA266_05700	COG0626	cystathionine gamma-synthase activity
CA266_05705	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
CA266_05710	COG0254	rRNA binding
CA266_05715	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CA266_05720	COG1609	Transcriptional regulator
CA266_05725	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CA266_05730	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CA266_05735	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CA266_05740	COG1575	Belongs to the MenA family. Type 1 subfamily
CA266_05745	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CA266_05750	COG3074	FtsZ-dependent cytokinesis
CA266_05765	COG1494	fructose-1,6-bisphosphatase
CA266_05770	COG2814	Major facilitator Superfamily
CA266_05785	COG3152	Membrane
CA266_05795	COG0149	triose-phosphate isomerase activity
CA266_05800	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CA266_05805	COG0205	6-phosphofructokinase activity
CA266_05810	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CA266_05815	COG3678	ATP-independent chaperone mediated protein folding
CA266_05820	COG0745	RESPONSE REGULATOR receiver
CA266_05825	COG2205	protein histidine kinase activity
CA266_05830	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CA266_05845	COG1045	serine acetyltransferase
CA266_05860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CA266_05865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CA266_05870	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CA266_05875	COG4942	peptidase
CA266_05880	COG2861	carbohydrate metabolic process
CA266_05885	COG1063	alcohol dehydrogenase
CA266_05890	COG0156	8-amino-7-oxononanoate synthase activity
CA266_05895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CA266_05900	COG0859	PFAM glycosyl transferase family 9
CA266_05905	COG0859	PFAM glycosyl transferase family 9
CA266_05920	COG0859	PFAM glycosyl transferase family 9
CA266_05930	COG0859	PFAM glycosyl transferase family 9
CA266_05935	COG0438	transferase activity, transferring glycosyl groups
CA266_05940	COG0438	transferase activity, transferring glycosyl groups
CA266_05950	COG1519	Transferase
CA266_05970	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CA266_05975	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CA266_05980	COG2003	Belongs to the UPF0758 family
CA266_05985	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CA266_05990	COG0756	dUTP diphosphatase activity
CA266_05995	COG1309	transcriptional regulator
CA266_06000	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CA266_06005	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CA266_06010	COG1561	YicC-like family, N-terminal region
CA266_06020	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CA266_06030	COG2860	membrane
CA266_06035	COG0194	GDP metabolic process
CA266_06040	COG1758	RNA polymerase activity
CA266_06045	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CA266_06050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CA266_06055	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CA266_06060	COG0786	glutamate:sodium symporter activity
CA266_06065	COG2233	PERMEase
CA266_06070	COG2982	Protein involved in outer membrane biogenesis
CA266_06075	COG0456	acetyltransferase
CA266_06080	COG1490	D-aminoacyl-tRNA deacylase activity
CA266_06085	COG1295	ribonuclease BN
CA266_06090	COG1011	Hydrolase
CA266_06095	COG1217	gtp-binding protein TYPA
CA266_06105	COG3852	Histidine kinase
CA266_06120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CA266_06125	COG3078	GTPase activator activity
CA266_06130	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CA266_06135	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CA266_06135	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CA266_06140	COG0204	Acyl-transferase
CA266_06145	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CA266_06150	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CA266_06155	COG3084	Protein conserved in bacteria
CA266_06160	COG0746	molybdenum cofactor guanylyltransferase activity
CA266_06165	COG1763	Mo-molybdopterin cofactor biosynthetic process
CA266_06190	COG2186	Transcriptional regulator
CA266_06195	COG0477	Major facilitator Superfamily
CA266_06200	COG1609	Transcriptional regulator
CA266_06205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CA266_06215	COG1172	Belongs to the binding-protein-dependent transport system permease family
CA266_06220	COG1129	ABC transporter
CA266_06225	COG1869	D-ribose catabolic process
CA266_06230	COG3158	transport of potassium into the cell
CA266_06235	COG0714	Associated with various cellular activities
CA266_06240	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CA266_06245	COG2502	aspartate--ammonia ligase
CA266_06250	COG1522	sequence-specific DNA binding
CA266_06255	COG0716	FMN binding
CA266_06260	COG0445	tRNA wobble uridine modification
CA266_06265	COG0357	Ribosomal RNA small subunit methyltransferase G
CA266_06270	COG3312	ion transport
CA266_06285	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CA266_06290	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CA266_06295	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CA266_06300	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CA266_06305	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CA266_06310	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CA266_06315	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CA266_06325	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CA266_06330	COG0573	inorganic phosphate transmembrane transporter activity
CA266_06335	COG0581	inorganic phosphate transmembrane transporter activity
CA266_06345	COG0704	Plays a role in the regulation of phosphate uptake
CA266_06350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CA266_06355	COG0765	amino acid transport
CA266_06360	COG0765	amino acid transport
CA266_06365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CA266_06370	COG0494	nUDIX hydrolase
CA266_06375	COG2252	PERMEase
CA266_06385	COG0431	NADPH-dependent FMN reductase
CA266_06390	COG2091	lysine biosynthetic process via aminoadipic acid
CA266_06415	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CA266_06420	COG0706	membrane insertase activity
CA266_06425	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CA266_06430	COG0594	ribonuclease P activity
CA266_06445	COG0592	DNA-directed DNA polymerase activity
CA266_06450	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CA266_06455	COG0187	DNA topoisomerase II activity
CA266_06460	COG0561	phosphatase activity
CA266_06465	COG2423	ornithine cyclodeaminase activity
CA266_06470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CA266_06475	COG0823	Involved in the tonB-independent uptake of proteins
CA266_06480	COG5645	(Lipo)protein
CA266_06485	COG0071	Belongs to the small heat shock protein (HSP20) family
CA266_06490	COG0071	Belongs to the small heat shock protein (HSP20) family
CA266_06495	COG2985	domain, Protein
CA266_06500	COG3977	Valine--pyruvate aminotransferase
CA266_06505	COG0366	Alpha amylase catalytic
CA266_06515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CA266_06520	COG2814	Major facilitator Superfamily
CA266_06525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CA266_06535	COG1609	Transcriptional regulator
CA266_06540	COG2885	chlorophyll binding
CA266_06550	COG2818	Glycosylase
CA266_06560	COG0752	glycyl-tRNA synthetase alpha subunit
CA266_06565	COG0751	glycine-tRNA ligase activity
CA266_06575	COG2213	PTS system mannitol-specific
CA266_06575	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CA266_06580	COG0246	Mannitol dehydrogenase
CA266_06585	COG3722	fumarate hydratase activity
CA266_06595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CA266_06610	COG2258	MOSC domain
CA266_06620	COG0840	transmembrane signaling receptor activity
CA266_06625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CA266_06635	COG0437	4 iron, 4 sulfur cluster binding
CA266_06640	COG2864	formate dehydrogenase
CA266_06645	COG3058	Necessary for formate dehydrogenase activity
CA266_06655	COG0625	glutathione transferase activity
CA266_06660	COG1921	L-seryl-tRNASec selenium transferase activity
CA266_06665	COG3276	selenocysteine insertion sequence binding
CA266_06685	COG3274	enterobacterial common antigen metabolic process
CA266_06700	COG0402	S-adenosylhomocysteine deaminase activity
CA266_06715	COG0583	DNA-binding transcription factor activity
CA266_06720	COG2807	transmembrane transport
CA266_06800	COG1902	pentaerythritol trinitrate reductase activity
CA266_06805	COG2814	Major facilitator Superfamily
CA266_06835	COG1846	Transcriptional regulator
CA266_06840	COG1764	response to oxidative stress
CA266_06845	COG2194	sulfuric ester hydrolase activity
CA266_06850	COG2197	response regulator
CA266_06860	COG2271	Major facilitator Superfamily
CA266_06890	COG0747	negative chemotaxis
CA266_06895	COG0601	transmembrane transport
CA266_06900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CA266_06905	COG0444	Belongs to the ABC transporter superfamily
CA266_06910	COG4608	Belongs to the ABC transporter superfamily
CA266_06915	COG2194	sulfuric ester hydrolase activity
CA266_06940	COG1215	transferase activity, transferring glycosyl groups
CA266_06945	COG1215	transferase activity, transferring glycosyl groups
CA266_06950	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CA266_06955	COG0457	Tetratricopeptide repeat
CA266_06955	COG3118	belongs to the thioredoxin family
CA266_06960	COG2199	diguanylate cyclase activity
CA266_06960	COG2200	EAL domain
CA266_06965	COG1301	dicarboxylic acid transport
CA266_06970	COG0612	Peptidase, M16
CA266_06975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CA266_06985	COG0248	Ppx GppA phosphatase
CA266_06995	COG3118	belongs to the thioredoxin family
CA266_07000	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CA266_07005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CA266_07015	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CA266_07020	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CA266_07025	COG1088	dTDP-glucose 4,6-dehydratase activity
CA266_07030	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CA266_07035	COG0456	acetyltransferase
CA266_07040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CA266_07045	COG2244	polysaccharide biosynthetic process
CA266_07050	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CA266_07060	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CA266_07090	COG3071	HemY protein
CA266_07095	COG2959	enzyme of heme biosynthesis
CA266_07105	COG0181	hydroxymethylbilane synthase activity
CA266_07110	COG3072	Adenylate cyclase
CA266_07115	COG1965	Belongs to the frataxin family
CA266_07120	COG5567	small periplasmic lipoprotein
CA266_07125	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CA266_07130	COG3159	Protein conserved in bacteria
CA266_07140	COG1011	Hydrolase
CA266_07145	COG0210	DNA helicase
CA266_07165	COG2050	protein possibly involved in aromatic compounds catabolism
CA266_07180	COG1280	lysine exporter protein (LysE YggA)
CA266_07185	COG1280	lysine exporter protein (LysE YggA)
CA266_07190	COG2267	carboxylic ester hydrolase activity
CA266_07195	COG0561	phosphatase activity
CA266_07200	COG0584	glycerophosphoryl diester phosphodiesterase
CA266_07205	COG2271	Major facilitator Superfamily
CA266_07210	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CA266_07220	COG0247	lactate metabolic process
CA266_07235	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CA266_07240	COG0425	Belongs to the sulfur carrier protein TusA family
CA266_07245	COG2217	Heavy metal translocating P-type atpase
CA266_07260	COG3714	YhhN family
CA266_07270	COG3776	membrane
CA266_07275	COG0742	ribosomal rna small subunit methyltransferase
CA266_07280	COG0552	protein localization to endoplasmic reticulum
CA266_07280	COG0552	protein localization to endoplasmic reticulum
CA266_07285	COG2884	Cell division ATP-binding protein ftsE
CA266_07290	COG2177	Part of the ABC transporter FtsEX involved in
CA266_07310	COG0456	acetyltransferase
CA266_07320	COG0559	Belongs to the binding-protein-dependent transport system permease family
CA266_07325	COG4177	L-phenylalanine transmembrane transporter activity
CA266_07340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CA266_07345	COG1653	transport
CA266_07350	COG1175	transmembrane transport
CA266_07360	COG3842	ATPase activity
CA266_07365	COG0584	glycerophosphoryl diester phosphodiesterase
CA266_07380	COG0697	spore germination
CA266_07390	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CA266_07395	COG0412	Dienelactone hydrolase
CA266_07410	COG0586	Pfam SNARE associated Golgi protein
CA266_07415	COG1322	Protein conserved in bacteria
CA266_07420	COG2226	methyltransferase
CA266_07425	COG3165	ubiquinone biosynthetic process from chorismate
CA266_07430	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CA266_07435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CA266_07445	COG0805	protein transport
CA266_07450	COG0084	hydrolase, TatD family'
CA266_07480	COG0183	Belongs to the thiolase family
CA266_07485	COG1024	Enoyl-CoA hydratase
CA266_07485	COG1250	3-hydroxyacyl-CoA dehydrogenase
CA266_07495	COG0006	proline dipeptidase activity
CA266_07500	COG1739	Uncharacterized protein family UPF0029
CA266_07505	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CA266_07535	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CA266_07540	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CA266_07540	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CA266_07545	COG1072	(Pantothenic acid kinase))
CA266_07580	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CA266_07590	COG0250	Participates in transcription elongation, termination and antitermination
CA266_07605	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CA266_07615	COG0085	RNA polymerase activity
CA266_07620	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CA266_07635	COG5002	protein histidine kinase activity
CA266_07635	COG3850	Histidine kinase
CA266_07650	COG2022	thiamine diphosphate biosynthetic process
CA266_07655	COG2104	thiamine diphosphate biosynthetic process
CA266_07660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CA266_07665	COG0352	thiamine-phosphate diphosphorylase activity
CA266_07670	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CA266_07675	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CA266_07680	COG2816	NAD+ diphosphatase activity
CA266_07685	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CA266_07690	COG1515	deoxyribonuclease V activity
CA266_07710	COG0151	Belongs to the GarS family
CA266_07715	COG0138	bifunctional purine biosynthesis protein purh
CA266_07745	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CA266_07750	COG3162	membrane
CA266_07755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CA266_07760	COG1301	dicarboxylic acid transport
CA266_07765	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CA266_07765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CA266_07770	COG3433	isochorismatase activity
CA266_07770	COG2226	methyltransferase
CA266_07770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CA266_07775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CA266_07780	COG4774	siderophore transport
CA266_07780	COG1629	transport
CA266_07785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CA266_07790	COG3391	amine dehydrogenase activity
CA266_07795	COG4771	TonB-dependent receptor
CA266_07800	COG2382	esterase
CA266_07810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CA266_07810	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CA266_07820	COG1169	isochorismate synthase
CA266_07825	COG1021	2,3-dihydroxybenzoate-AMP ligase
CA266_07830	COG1535	isochorismatase
CA266_07830	COG3433	isochorismatase activity
CA266_07840	COG3647	Membrane
CA266_07845	COG0745	RESPONSE REGULATOR receiver
CA266_07870	COG3188	usher protein
CA266_07875	COG3121	Chaperone
CA266_07920	COG1309	transcriptional regulator
CA266_07925	COG4232	protein-disulfide reductase activity
CA266_07935	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CA266_07950	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CA266_07965	COG1509	lysine 2,3-aminomutase activity
CA266_07970	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CA266_07975	COG5510	response to toxic substance
CA266_07980	COG5510	response to toxic substance
CA266_07995	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CA266_08000	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CA266_08005	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CA266_08010	COG1053	succinate dehydrogenase
CA266_08015	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CA266_08020	COG3264	Mechanosensitive ion channel
CA266_08020	COG1511	domain protein
CA266_08030	COG1162	GTPase activity
CA266_08035	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CA266_08055	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CA266_08060	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CA266_08060	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CA266_08065	COG0802	atpase or kinase
CA266_08070	COG0860	N-Acetylmuramoyl-L-alanine amidase
CA266_08075	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CA266_08080	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CA266_08090	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CA266_08095	COG0330	HflC and HflK could
CA266_08100	COG0330	HflC and HflK could
CA266_08105	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CA266_08110	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CA266_08115	COG1959	2 iron, 2 sulfur cluster binding
CA266_08120	COG0557	exoribonuclease II activity
CA266_08125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CA266_08130	COG1960	acyl-CoA dehydrogenase activity
CA266_08135	COG3766	membrane
CA266_08145	COG3650	response to hydrogen peroxide
CA266_08150	COG1073	alpha beta
CA266_08170	COG0360	Binds together with S18 to 16S ribosomal RNA
CA266_08180	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CA266_08185	COG0359	binds to the 23S rRNA
CA266_08195	COG3061	Opacity-associated protein A
CA266_08200	COG0545	Peptidyl-prolyl cis-trans isomerase
CA266_08205	COG0737	Belongs to the 5'-nucleotidase family
CA266_08215	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CA266_08225	COG1253	flavin adenine dinucleotide binding
CA266_08230	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CA266_08235	COG0729	surface antigen
CA266_08240	COG2911	Protein conserved in bacteria
CA266_08245	COG2105	PFAM AIG2 family protein
CA266_08250	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CA266_08255	COG0840	transmembrane signaling receptor activity
CA266_08260	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CA266_08265	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CA266_08280	COG1438	arginine binding
CA266_08285	COG0039	L-malate dehydrogenase activity
CA266_08290	COG3423	Transcriptional regulator
CA266_08300	COG0142	geranyltranstransferase activity
CA266_08305	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CA266_08310	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CA266_08315	COG0697	spore germination
CA266_08320	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CA266_08325	COG0642	Histidine kinase
CA266_08330	COG0745	RESPONSE REGULATOR receiver
CA266_08335	COG2027	D-alanyl-D-alanine carboxypeptidase
CA266_08345	COG1534	Rna-binding protein
CA266_08350	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CA266_08360	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CA266_08365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CA266_08370	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CA266_08385	COG0779	Required for maturation of 30S ribosomal subunits
CA266_08390	COG0195	Participates in both transcription termination and antitermination
CA266_08395	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CA266_08400	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CA266_08405	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CA266_08410	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CA266_08415	COG1185	polyribonucleotide nucleotidyltransferase activity
CA266_08430	COG0513	Belongs to the DEAD box helicase family
CA266_08435	COG2391	methyltransferase activity
CA266_08440	COG0425	Belongs to the sulfur carrier protein TusA family
CA266_08445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CA266_08465	COG0826	peptidase U32
CA266_08470	COG0826	peptidase U32
CA266_08475	COG3154	lipid carrier protein
CA266_08480	COG3153	acetyltransferase
CA266_08485	COG2827	Endonuclease containing a URI domain
CA266_08495	COG0531	amino acid
CA266_08500	COG1982	Orn Lys Arg decarboxylase major
CA266_08510	COG3787	Belongs to the UPF0306 family
CA266_08515	COG0702	epimerase
CA266_08520	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CA266_08530	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CA266_08535	COG3454	Phosphonate metabolism
CA266_08540	COG4778	phosphonate C-P lyase system protein PhnL
CA266_08545	COG4107	phosphonate C-P lyase system protein PhnK
CA266_08550	COG3627	carbon phosphorus lyase activity
CA266_08555	COG3626	phosphonate metabolism
CA266_08560	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CA266_08565	COG3624	Phosphonate C-P lyase system protein PhnG
CA266_08570	COG2188	Transcriptional regulator
CA266_08575	COG0701	Predicted permease
CA266_08590	COG0602	queuosine metabolic process
CA266_08600	COG0583	DNA-binding transcription factor activity
CA266_08605	COG2249	NAD(P)H dehydrogenase (quinone) activity
CA266_08610	COG0366	Alpha amylase catalytic
CA266_08615	COG1263	PTS System
CA266_08615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CA266_08625	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CA266_08630	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CA266_08650	COG0540	Belongs to the ATCase OTCase family
CA266_08660	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CA266_08675	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CA266_08680	COG0456	acetyltransferase
CA266_08690	COG2927	DNA polymerase III (CHI subunit)
CA266_08695	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CA266_08700	COG0795	lipopolysaccharide-transporting ATPase activity
CA266_08705	COG0795	lipopolysaccharide-transporting ATPase activity
CA266_08730	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CA266_08740	COG0732	type I restriction modification DNA specificity domain
CA266_08745	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CA266_08765	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CA266_08810	COG2723	6-phospho-beta-galactosidase activity
CA266_08815	COG1263	PTS System
CA266_08815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CA266_08820	COG1609	Transcriptional regulator
CA266_08830	COG0523	cobalamin synthesis protein
CA266_08835	COG2879	small protein
CA266_08840	COG1966	Carbon starvation protein
CA266_08850	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CA266_08860	COG0174	glutamine synthetase
CA266_08885	COG0583	DNA-binding transcription factor activity
CA266_08890	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CA266_08905	COG1250	3-hydroxyacyl-CoA dehydrogenase
CA266_08910	COG2610	gluconate transmembrane transporter activity
CA266_08915	COG1028	Short-chain dehydrogenase reductase Sdr
CA266_08925	COG2207	Transcriptional regulator
CA266_08935	COG2207	Transcriptional regulator
CA266_08935	COG3708	Transcriptional regulator
CA266_08940	COG1376	ErfK ybiS ycfS ynhG family protein
CA266_08970	COG0811	peptide transport
CA266_09005	COG1454	alcohol dehydrogenase
CA266_09015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CA266_09055	COG1113	amino acid transport
CA266_09075	COG1028	Short-chain dehydrogenase reductase Sdr
CA266_09080	COG1846	Transcriptional regulator
CA266_09095	COG1012	belongs to the aldehyde dehydrogenase family
CA266_09110	COG3971	2-oxopent-4-enoate hydratase activity
CA266_09130	COG2368	4-hydroxyphenylacetate
CA266_09135	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CA266_09140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CA266_09150	COG1028	Short-chain dehydrogenase reductase Sdr
CA266_09155	COG0179	Fumarylacetoacetate (FAA) hydrolase
CA266_09160	COG4948	Mandelate Racemase Muconate Lactonizing
CA266_09165	COG3618	amidohydrolase
CA266_09170	COG1028	Short-chain dehydrogenase reductase Sdr
CA266_09175	COG3254	rhamnose metabolic process
CA266_09180	COG0738	Major facilitator superfamily
CA266_09200	COG1309	transcriptional regulator
CA266_09205	COG3706	GGDEF domain
CA266_09235	COG0667	Aldo Keto reductase
CA266_09240	COG2813	Specifically methylates the guanine in position
CA266_09245	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CA266_09255	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CA266_09260	COG2823	Periplasmic or secreted lipoprotein
CA266_09265	COG5487	UPF0391 membrane protein
CA266_09270	COG3237	CsbD-like
CA266_09275	COG4667	esterase of the alpha-beta hydrolase superfamily
CA266_09280	COG0084	hydrolase, TatD family'
CA266_09285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CA266_09290	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CA266_09295	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CA266_09300	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CA266_09305	COG0813	purine-nucleoside phosphorylase activity
CA266_09310	COG3726	membrane protein affecting hemolysin expression
CA266_09315	COG0560	Phosphoserine phosphatase
CA266_09335	COG0604	alcohol dehydrogenase
CA266_09345	COG0488	(ABC) transporter
CA266_09350	COG2885	chlorophyll binding
CA266_09355	COG2199	diguanylate cyclase activity
CA266_09365	COG0741	lytic transglycosylase activity
CA266_09370	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CA266_09375	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CA266_09380	COG0406	alpha-ribazole phosphatase activity
CA266_09385	COG2207	Transcriptional regulator
CA266_09385	COG3708	Transcriptional regulator
CA266_09390	COG3045	CreA protein
CA266_09395	COG0745	RESPONSE REGULATOR receiver
CA266_09425	COG3022	response to hydroperoxide
CA266_09430	COG1115	amino acid carrier protein
CA266_09435	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CA266_09440	COG0521	Mo-molybdopterin cofactor biosynthetic process
CA266_09450	COG1584	GPR1 FUN34 yaaH family protein
CA266_09455	COG0443	Heat shock 70 kDa protein
CA266_09460	COG0484	heat shock protein binding
CA266_09465	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CA266_09470	COG0583	DNA-binding transcription factor activity
CA266_09475	COG0268	Binds directly to 16S ribosomal RNA
CA266_09480	COG0196	riboflavin kinase activity
CA266_09485	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CA266_09490	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CA266_09495	COG1047	Peptidyl-prolyl cis-trans
CA266_09500	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CA266_09525	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CA266_09530	COG0505	Belongs to the CarA family
CA266_09540	COG2249	NAD(P)H dehydrogenase (quinone) activity
CA266_09555	COG2966	Psort location CytoplasmicMembrane, score
CA266_09565	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CA266_09575	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CA266_09580	COG2967	ApaG domain
CA266_09585	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CA266_09590	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CA266_09600	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CA266_09610	COG0564	pseudouridine synthase activity
CA266_09615	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CA266_09620	COG0417	DNA replication proofreading
CA266_09625	COG0586	Pfam SNARE associated Golgi protein
CA266_09630	COG0440	acetolactate synthase activity
CA266_09635	COG0028	Belongs to the TPP enzyme family
CA266_09650	COG1178	ABC-type Fe3 transport system permease component
CA266_09655	COG4143	(ABC) transporter
CA266_09670	COG2814	Major facilitator Superfamily
CA266_09675	COG0471	metal ion transport
CA266_09680	COG0066	3-isopropylmalate dehydratase activity
CA266_09685	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CA266_09690	COG0473	3-isopropylmalate dehydrogenase activity
CA266_09695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CA266_09705	COG0583	DNA-binding transcription factor activity
CA266_09710	COG1022	Amp-dependent synthetase and ligase
CA266_09715	COG0028	Belongs to the TPP enzyme family
CA266_09735	COG2001	Belongs to the MraZ family
CA266_09740	COG0275	rRNA processing
CA266_09745	COG3116	cell division
CA266_09750	COG0768	penicillin binding
CA266_09755	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CA266_09760	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CA266_09765	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CA266_09775	COG0772	Belongs to the SEDS family
CA266_09780	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CA266_09785	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CA266_09795	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CA266_09800	COG0849	cell division
CA266_09805	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CA266_09825	COG0653	protein targeting
CA266_09830	COG0494	nUDIX hydrolase
CA266_09835	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CA266_09840	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CA266_09850	COG0516	GMP reductase activity
CA266_09855	COG1459	type II secretion system
CA266_09860	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CA266_09865	COG4969	Belongs to the N-Me-Phe pilin family
CA266_09875	COG3023	N-Acetylmuramoyl-L-alanine amidase
CA266_09880	COG3725	Membrane protein required for beta-lactamase induction
CA266_09885	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CA266_09895	COG0316	Belongs to the HesB IscA family
CA266_09900	COG2860	membrane
CA266_09910	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CA266_09915	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CA266_09920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CA266_09930	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CA266_09935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CA266_09940	COG3956	TIGRFAM MazG family protein
CA266_09950	COG0504	CTP synthase activity
CA266_09980	COG2986	histidine ammonia-lyase
CA266_09990	COG2271	Major facilitator Superfamily
CA266_09995	COG0602	queuosine metabolic process
CA266_10000	COG0720	synthase
CA266_10005	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CA266_10010	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CA266_10015	COG0175	sulfate reduction
CA266_10020	COG2234	aminopeptidase activity
CA266_10025	COG1648	precorrin-2 dehydrogenase activity
CA266_10025	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CA266_10030	COG0175	sulfate reduction
CA266_10035	COG2895	sulfate adenylyltransferase (ATP) activity
CA266_10050	COG1126	abc transporter atp-binding protein
CA266_10055	COG0765	amino acid transport
CA266_10065	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CA266_10070	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CA266_10075	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CA266_10080	COG0585	pseudouridine synthase activity
CA266_10085	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CA266_10090	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CA266_10095	COG1388	LysM domain
CA266_10095	COG4942	peptidase
CA266_10100	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CA266_10105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CA266_10115	COG0667	Aldo Keto reductase
CA266_10125	COG0583	DNA-binding transcription factor activity
CA266_10130	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CA266_10135	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CA266_10140	COG2723	6-phospho-beta-galactosidase activity
CA266_10145	COG2169	Transcriptional regulator
CA266_10145	COG1917	Cupin 2, conserved barrel domain protein
CA266_10170	COG2137	regulation of response to DNA damage stimulus
CA266_10180	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CA266_10185	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CA266_10215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CA266_10220	COG1238	metal cluster binding
CA266_10225	COG2918	glutathione biosynthetic process
CA266_10235	COG4536	flavin adenine dinucleotide binding
CA266_10240	COG4137	Cytochrome C assembly protein
CA266_10245	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CA266_10250	COG0228	four-way junction DNA binding
CA266_10255	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CA266_10260	COG0336	Belongs to the RNA methyltransferase TrmD family
CA266_10265	COG0335	large ribosomal subunit rRNA binding
CA266_10285	COG3137	Salt-induced outer membrane protein
CA266_10290	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CA266_10295	COG0287	Prephenate dehydrogenase
CA266_10295	COG1605	Chorismate mutase
CA266_10300	COG1605	Chorismate mutase
CA266_10300	COG0077	Prephenate dehydratase
CA266_10310	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CA266_10315	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CA266_10320	COG0564	pseudouridine synthase activity
CA266_10330	COG0542	response to heat
CA266_10360	COG0656	L-ascorbic acid biosynthetic process
CA266_10365	COG0583	DNA-binding transcription factor activity
CA266_10370	COG2814	Major facilitator Superfamily
CA266_10375	COG3021	interspecies interaction between organisms
CA266_10380	COG0741	lytic transglycosylase activity
CA266_10380	COG1388	LysM domain
CA266_10385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CA266_10390	COG2226	methyltransferase
CA266_10395	COG0328	RNA-DNA hybrid ribonuclease activity
CA266_10400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CA266_10425	COG0436	Aminotransferase
CA266_10430	COG0235	Class ii aldolase
CA266_10435	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CA266_10440	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CA266_10445	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CA266_10450	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CA266_10460	COG1960	acyl-CoA dehydrogenase activity
CA266_10465	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CA266_10470	COG0121	glutamine amidotransferase
CA266_10475	COG3034	peptidoglycan biosynthetic process
CA266_10480	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CA266_10485	COG1805	sodium ion transport
CA266_10490	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CA266_10495	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CA266_10500	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CA266_10505	COG2871	sodium ion transport
CA266_10510	COG1477	protein flavinylation
CA266_10515	COG2991	Protein conserved in bacteria
CA266_10530	COG0584	glycerophosphoryl diester phosphodiesterase
CA266_10535	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CA266_10540	COG2195	Cleaves the N-terminal amino acid of tripeptides
CA266_10545	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CA266_10550	COG1073	alpha beta
CA266_10575	COG1560	Kdo2-lipid A biosynthetic process
CA266_10585	COG3459	Glycosyltransferase 36 associated
CA266_10600	COG2314	TM2 domain
CA266_10630	COG3038	cytochrome b561
CA266_10635	COG0747	negative chemotaxis
CA266_10640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CA266_10645	COG1733	regulation of RNA biosynthetic process
CA266_10650	COG2249	NAD(P)H dehydrogenase (quinone) activity
CA266_10665	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CA266_10670	COG2207	Transcriptional regulator
CA266_10675	COG1012	belongs to the aldehyde dehydrogenase family
CA266_10685	COG2169	Transcriptional regulator
CA266_10685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CA266_10710	COG3961	Belongs to the TPP enzyme family
CA266_10740	COG1349	DNA-binding transcription factor activity
CA266_10745	COG0346	lactoylglutathione lyase activity
CA266_10760	COG1335	isochorismatase
CA266_10775	COG3011	Protein conserved in bacteria
CA266_10785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CA266_10790	COG3416	Protein conserved in bacteria
CA266_10800	COG2226	methyltransferase
CA266_10850	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CA266_10870	COG1595	DNA-templated transcription, initiation
CA266_10905	COG3123	guanosine phosphorylase activity
CA266_10910	COG2974	May be involved in recombination
CA266_10915	COG1940	carbohydrate kinase activity
CA266_10935	COG0419	ATPase involved in DNA repair
CA266_10940	COG0420	3'-5' exonuclease activity
CA266_10945	COG0745	RESPONSE REGULATOR receiver
CA266_10950	COG5002	protein histidine kinase activity
CA266_10970	COG3093	addiction module antidote protein HigA
CA266_10985	COG0668	transmembrane transport
CA266_10990	COG0366	Alpha amylase catalytic
CA266_11000	COG0450	alkyl hydroperoxide reductase
CA266_11005	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
CA266_11010	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CA266_11015	COG0343	queuine tRNA-ribosyltransferase activity
CA266_11020	COG1862	Preprotein translocase
CA266_11030	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CA266_11035	COG4238	major outer membrane lipoprotein
CA266_11040	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CA266_11045	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CA266_11045	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CA266_11050	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CA266_11055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CA266_11060	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CA266_11065	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CA266_11070	COG0667	Aldo Keto reductase
CA266_11075	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CA266_11080	COG0142	geranyltranstransferase activity
CA266_11085	COG1722	exodeoxyribonuclease VII activity
CA266_11090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CA266_11090	COG0301	tRNA thio-modification
CA266_11095	COG0693	protein deglycase activity
CA266_11100	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CA266_11105	COG1666	GTP binding
CA266_11110	COG2814	Major facilitator Superfamily
CA266_11115	COG0109	protoheme IX farnesyltransferase activity
CA266_11120	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CA266_11125	COG1845	cytochrome c oxidase, subunit III
CA266_11130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CA266_11135	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CA266_11140	COG2223	nitrite transmembrane transporter activity
CA266_11145	COG3056	Lipoprotein
CA266_11150	COG0271	Belongs to the BolA IbaG family
CA266_11155	COG0544	peptidyl-prolyl cis-trans isomerase activity
CA266_11165	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CA266_11170	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CA266_11180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CA266_11185	COG1555	photosystem II stabilization
CA266_11190	COG0824	Thioesterase
CA266_11195	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CA266_11200	COG4533	DNA binding
CA266_11205	COG0561	phosphatase activity
CA266_11215	COG1522	sequence-specific DNA binding
CA266_11220	COG1132	(ABC) transporter
CA266_11225	COG1132	(ABC) transporter
CA266_11230	COG0347	Belongs to the P(II) protein family
CA266_11235	COG0004	ammonium transporteR
CA266_11240	COG1946	Acyl-CoA thioesterase
CA266_11245	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CA266_11250	COG3695	enzyme binding
CA266_11275	COG1121	(ABC) transporter
CA266_11280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CA266_11285	COG0803	Belongs to the bacterial solute-binding protein 9 family
CA266_11290	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CA266_11295	COG0254	rRNA binding
CA266_11300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CA266_11305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CA266_11310	COG1309	transcriptional regulator
CA266_11315	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CA266_11320	COG1196	nuclear chromosome segregation
CA266_11320	COG3264	Mechanosensitive ion channel
CA266_11335	COG2832	Protein of unknown function (DUF454)
CA266_11340	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CA266_11345	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CA266_11355	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CA266_11360	COG0326	Molecular chaperone. Has ATPase activity
CA266_11365	COG0563	adenylate kinase activity
CA266_11370	COG3835	regulator
CA266_11375	COG2610	gluconate transmembrane transporter activity
CA266_11380	COG1929	Belongs to the glycerate kinase type-1 family
CA266_11385	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CA266_11390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CA266_11395	COG4651	solute:proton antiporter activity
CA266_11395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CA266_11400	COG2223	nitrite transmembrane transporter activity
CA266_11405	COG0737	Belongs to the 5'-nucleotidase family
CA266_11410	COG2027	D-alanyl-D-alanine carboxypeptidase
CA266_11415	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CA266_11420	COG3735	TraB family
CA266_11425	COG2217	Heavy metal translocating P-type atpase
CA266_11435	COG0778	Nitroreductase
CA266_11450	COG3321	synthase
CA266_11455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CA266_11460	COG0156	8-amino-7-oxononanoate synthase activity
CA266_11465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CA266_11470	COG1414	Transcriptional regulator
CA266_11470	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CA266_11490	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CA266_11495	COG1960	acyl-CoA dehydrogenase activity
CA266_11500	COG0789	Transcriptional regulator
CA266_11505	COG1585	Membrane protein implicated in regulation of membrane protease activity
CA266_11510	COG0330	HflC and HflK could
CA266_11515	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CA266_11520	COG3118	belongs to the thioredoxin family
CA266_11525	COG0300	oxidoreductase activity
CA266_11530	COG2755	lipolytic protein G-D-S-L family
CA266_11535	COG4181	ATPase activity
CA266_11540	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CA266_11550	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CA266_11555	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CA266_11560	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CA266_11565	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CA266_11570	COG0215	cysteine-tRNA ligase activity
CA266_11575	COG2501	S4 domain
CA266_11580	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CA266_11595	COG0582	viral genome integration into host DNA
CA266_11650	COG2199	diguanylate cyclase activity
CA266_11655	COG1278	Cold shock
CA266_11665	COG1126	abc transporter atp-binding protein
CA266_11670	COG0765	amino acid transport
CA266_11680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CA266_11685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CA266_11690	COG1473	amidohydrolase
CA266_11700	COG2814	Major facilitator Superfamily
CA266_11705	COG1309	transcriptional regulator
CA266_11710	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CA266_11720	COG3706	GGDEF domain
CA266_11730	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CA266_11735	COG0321	lipoyl(octanoyl) transferase activity
CA266_11745	COG1686	Belongs to the peptidase S11 family
CA266_11750	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CA266_11755	COG0772	Belongs to the SEDS family
CA266_11760	COG0768	penicillin binding
CA266_11765	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CA266_11770	COG0799	negative regulation of ribosome biogenesis
CA266_11775	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CA266_11780	COG1466	dna polymerase III delta subunit
CA266_11785	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CA266_11790	COG0495	leucyl-tRNA aminoacylation
CA266_11795	COG2888	peptidyl-tyrosine sulfation
CA266_11805	COG1957	nucleoside hydrolase
CA266_11810	COG1126	abc transporter atp-binding protein
CA266_11815	COG0765	amino acid transport
CA266_11820	COG0765	amino acid transport
CA266_11830	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CA266_11835	COG4535	Mg2 and Co2 transporter CorC
CA266_11840	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CA266_11845	COG1702	phosphate starvation-inducible protein PhoH
CA266_11850	COG2824	Alkylphosphonate utilization operon protein PhnA
CA266_11855	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CA266_11860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CA266_11895	COG0367	asparagine synthase
CA266_11900	COG3469	chitinase activity
CA266_11905	COG0647	UMP catabolic process
CA266_11910	COG1940	carbohydrate kinase activity
CA266_11910	COG1846	Transcriptional regulator
CA266_11915	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CA266_11920	COG0363	glucosamine-6-phosphate deaminase activity
CA266_11925	COG1263	PTS System
CA266_11925	COG2190	(PTS) system
CA266_11925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CA266_11930	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CA266_11950	COG0735	belongs to the Fur family
CA266_11965	COG0596	Alpha beta hydrolase
CA266_11970	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CA266_11975	COG0033	Phosphoglucomutase
CA266_11980	COG1695	Transcriptional regulator
CA266_11990	COG0745	RESPONSE REGULATOR receiver
CA266_11995	COG2205	protein histidine kinase activity
CA266_12000	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CA266_12005	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CA266_12010	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CA266_12025	COG3272	Protein of unknown function (DUF1722)
CA266_12035	COG5212	phosphodiesterase
CA266_12040	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CA266_12045	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CA266_12050	COG1984	allophanate hydrolase subunit 2
CA266_12055	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CA266_12090	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CA266_12095	COG1053	succinate dehydrogenase
CA266_12100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CA266_12105	COG0567	Dehydrogenase, E1 component
CA266_12110	COG0508	dehydrogenase complex catalyzes the overall conversion of
CA266_12115	COG0045	succinate-CoA ligase (ADP-forming) activity
CA266_12120	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CA266_12125	COG0737	Belongs to the 5'-nucleotidase family
CA266_12130	COG1271	oxidase subunit
CA266_12135	COG1294	oxidase, subunit
CA266_12140	COG4890	Cyd operon protein YbgT
CA266_12145	COG3790	cyd operon protein YbgE
CA266_12150	COG0824	Thioesterase
CA266_12155	COG0811	peptide transport
CA266_12160	COG0848	biopolymer transport protein
CA266_12165	COG3064	Membrane
CA266_12170	COG0823	Involved in the tonB-independent uptake of proteins
CA266_12175	COG2885	chlorophyll binding
CA266_12180	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CA266_12230	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CA266_12240	COG1230	cation diffusion facilitator family transporter
CA266_12245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CA266_12245	COG2205	protein histidine kinase activity
CA266_12250	COG2197	response regulator
CA266_12255	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CA266_12270	COG0588	phosphoglycerate mutase activity
CA266_12280	COG2017	converts alpha-aldose to the beta-anomer
CA266_12285	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CA266_12290	COG1085	galactose-1-phosphate uridylyltransferase
CA266_12305	COG1119	ATPase activity
CA266_12310	COG3585	molybdate ion transport
CA266_12310	COG2005	Transcriptional regulator
CA266_12315	COG4774	siderophore transport
CA266_12325	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CA266_12330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CA266_12335	COG1120	ATPase activity
CA266_12345	COG0725	ABC transporter, periplasmic molybdate-binding protein
CA266_12350	COG4149	molybdate abc transporter
CA266_12360	COG0561	phosphatase activity
CA266_12365	COG2706	6-phosphogluconolactonase activity
CA266_12370	COG1881	PFAM PEBP family protein
CA266_12425	COG0556	nucleotide-excision repair
CA266_12430	COG4628	conserved protein (DUF2132)
CA266_12435	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CA266_12440	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CA266_12445	COG0521	Mo-molybdopterin cofactor biosynthetic process
CA266_12450	COG0315	cyclic pyranopterin monophosphate synthase activity
CA266_12455	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CA266_12460	COG0314	molybdopterin synthase activity
CA266_12465	COG0670	Belongs to the BI1 family
CA266_12470	COG0842	Transport permease protein
CA266_12475	COG0842	Transport permease protein
CA266_12480	COG1131	(ABC) transporter
CA266_12485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CA266_12490	COG1309	transcriptional regulator
CA266_12495	COG0513	Belongs to the DEAD box helicase family
CA266_12500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CA266_12505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CA266_12515	COG3842	ATPase activity
CA266_12525	COG1840	ABC-type Fe3 transport system, periplasmic component
CA266_12530	COG2271	Major facilitator Superfamily
CA266_12545	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CA266_12565	COG0469	pyruvate kinase activity
CA266_12570	COG1028	Short-chain dehydrogenase reductase Sdr
CA266_12575	COG0583	DNA-binding transcription factor activity
CA266_12595	COG0583	DNA-binding transcription factor activity
CA266_12600	COG0586	Pfam SNARE associated Golgi protein
CA266_12610	COG4977	sequence-specific DNA binding
CA266_12615	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CA266_12620	COG1686	Belongs to the peptidase S11 family
CA266_12640	COG2354	Protein conserved in bacteria
CA266_12650	COG1464	Belongs to the NlpA lipoprotein family
CA266_12660	COG0456	acetyltransferase
CA266_12680	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CA266_12690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CA266_12695	COG0277	FAD linked oxidase domain protein
CA266_12710	COG1181	Belongs to the D-alanine--D-alanine ligase family
CA266_12720	COG0436	Aminotransferase
CA266_12730	COG1472	Belongs to the glycosyl hydrolase 3 family
CA266_12740	COG2345	Transcriptional regulator
CA266_12760	COG1846	Transcriptional regulator
CA266_12785	COG1192	Involved in chromosome partitioning
CA266_12800	COG0583	DNA-binding transcription factor activity
CA266_12810	COG1070	Carbohydrate kinase
CA266_12815	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CA266_12820	COG0697	spore germination
CA266_12865	COG1846	Transcriptional regulator
CA266_12875	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CA266_12890	COG1309	transcriptional regulator
CA266_12895	COG1464	Belongs to the NlpA lipoprotein family
CA266_12900	COG2011	ABC-type metal ion transport system permease component
CA266_12905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CA266_12910	COG0519	Catalyzes the synthesis of GMP from XMP
CA266_12930	COG2084	Dehydrogenase
CA266_12945	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CA266_12960	COG4807	Protein conserved in bacteria
CA266_12980	COG1802	Transcriptional regulator
CA266_13000	COG0411	ABC transporter
CA266_13050	COG0583	DNA-binding transcription factor activity
CA266_13055	COG2897	thiosulfate sulfurtransferase activity
CA266_13060	COG0494	nUDIX hydrolase
CA266_13075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CA266_13085	COG0625	glutathione transferase activity
CA266_13095	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CA266_13105	COG1335	isochorismatase
CA266_13110	COG0583	DNA-binding transcription factor activity
CA266_13130	COG1732	Glycine betaine
CA266_13135	COG1174	glycine betaine transport
CA266_13140	COG1125	glycine betaine transport
CA266_13145	COG1174	glycine betaine transport
CA266_13160	COG0583	DNA-binding transcription factor activity
CA266_13170	COG0697	spore germination
CA266_13205	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CA266_13220	COG0625	glutathione transferase activity
CA266_13230	COG1942	4-Oxalocrotonate Tautomerase
CA266_13240	COG1522	sequence-specific DNA binding
CA266_13245	COG0697	spore germination
CA266_13265	COG2079	MmgE PrpD family protein
CA266_13270	COG1280	lysine exporter protein (LysE YggA)
CA266_13280	COG0477	Major facilitator Superfamily
CA266_13290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CA266_13315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CA266_13320	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CA266_13335	COG1309	transcriptional regulator
CA266_13340	COG0456	acetyltransferase
CA266_13340	COG1214	PFAM Peptidase M22, glycoprotease
CA266_13350	COG0668	transmembrane transport
CA266_13355	COG1126	abc transporter atp-binding protein
CA266_13360	COG0765	amino acid transport
CA266_13365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CA266_13370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CA266_13380	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CA266_13385	COG2731	YhcH YjgK YiaL family protein
CA266_13395	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CA266_13400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CA266_13415	COG2610	gluconate transmembrane transporter activity
CA266_13420	COG3622	Belongs to the hyi family
CA266_13425	COG0235	Class ii aldolase
CA266_13430	COG3395	kinase activity
CA266_13435	COG2084	Dehydrogenase
CA266_13440	COG1349	DNA-binding transcription factor activity
CA266_13450	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CA266_13455	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CA266_13475	COG5002	protein histidine kinase activity
CA266_13480	COG0745	RESPONSE REGULATOR receiver
CA266_13485	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CA266_13490	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CA266_13505	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CA266_13510	COG1309	transcriptional regulator
CA266_13515	COG1012	belongs to the aldehyde dehydrogenase family
CA266_13520	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CA266_13525	COG0069	glutamate synthase activity
CA266_13535	COG2200	EAL domain
CA266_13545	COG3121	Chaperone
CA266_13550	COG3188	usher protein
CA266_13560	COG3708	Transcriptional regulator
CA266_13560	COG2207	Transcriptional regulator
CA266_13565	COG0579	oxidoreductase
CA266_13575	COG0625	glutathione transferase activity
CA266_13580	COG0640	Transcriptional regulator
CA266_13590	COG1335	isochorismatase
CA266_13595	COG0583	DNA-binding transcription factor activity
CA266_13610	COG3811	Belongs to the UPF0386 family
CA266_13615	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CA266_13625	COG0583	DNA-binding transcription factor activity
CA266_13645	COG0488	(ABC) transporter
CA266_13650	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CA266_13655	COG0303	'Molybdopterin
CA266_13670	COG4172	Belongs to the ABC transporter superfamily
CA266_13675	COG0747	negative chemotaxis
CA266_13680	COG0601	transmembrane transport
CA266_13685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CA266_13710	COG0583	DNA-binding transcription factor activity
CA266_13715	COG0477	Major facilitator Superfamily
CA266_13720	COG0302	gtp cyclohydrolase
CA266_13725	COG2311	Membrane
CA266_13730	COG1609	Transcriptional regulator
CA266_13755	COG2949	membrane
CA266_13760	COG0281	malic enzyme
CA266_13765	COG0295	cytidine deaminase activity
CA266_13770	COG1346	cytolysis
CA266_13775	COG1380	Effector of murein hydrolase LrgA
CA266_13780	COG2814	Major facilitator Superfamily
CA266_13790	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CA266_13790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CA266_13795	COG0489	protein tyrosine kinase activity
CA266_13805	COG0572	uridine kinase
CA266_13810	COG0717	Belongs to the dCTP deaminase family
CA266_13815	COG2982	Protein involved in outer membrane biogenesis
CA266_13820	COG3069	C4-dicarboxylate transmembrane transporter activity
CA266_13825	COG1253	flavin adenine dinucleotide binding
CA266_13830	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CA266_13835	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CA266_13845	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CA266_13850	COG3206	protein involved in exopolysaccharide biosynthesis
CA266_13850	COG0489	protein tyrosine kinase activity
CA266_13855	COG1083	cytidylyl-transferase
CA266_13860	COG2089	acid synthase
CA266_13865	COG2244	polysaccharide biosynthetic process
CA266_13870	COG0110	maltose O-acetyltransferase activity
CA266_13950	COG0438	transferase activity, transferring glycosyl groups
CA266_13970	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CA266_13975	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CA266_13975	COG0140	phosphoribosyl-ATP diphosphatase activity
CA266_13980	COG0107	imidazoleglycerol-phosphate synthase activity
CA266_13985	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CA266_13995	COG0131	Imidazoleglycerol-phosphate dehydratase
CA266_13995	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CA266_14000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CA266_14005	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CA266_14010	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CA266_14020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CA266_14025	COG0583	DNA-binding transcription factor activity
CA266_14030	COG2814	Major facilitator Superfamily
CA266_14045	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CA266_14050	COG3153	acetyltransferase
CA266_14050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CA266_14055	COG0598	Magnesium transport protein CorA
CA266_14065	COG2133	pyrroloquinoline quinone binding
CA266_14070	COG0625	glutathione transferase activity
CA266_14090	COG0626	cystathionine gamma-synthase activity
CA266_14100	COG1686	Belongs to the peptidase S11 family
CA266_14125	COG3539	Fimbrial protein
CA266_14130	COG3188	usher protein
CA266_14135	COG3121	Chaperone
CA266_14155	COG0545	Peptidyl-prolyl cis-trans isomerase
CA266_14160	COG2197	response regulator
CA266_14165	COG1760	l-serine dehydratase
CA266_14170	COG0814	amino acid
CA266_14175	COG1349	DNA-binding transcription factor activity
CA266_14180	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CA266_14190	COG0671	phosphoesterase, PA-phosphatase related
CA266_14200	COG4574	serine-type endopeptidase inhibitor activity
CA266_14210	COG0569	domain protein
CA266_14210	COG2985	domain, Protein
CA266_14230	COG0189	ligase activity
CA266_14240	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CA266_14245	COG3842	ATPase activity
CA266_14250	COG1176	ABC-type spermidine putrescine transport system, permease component I
CA266_14255	COG1177	transmembrane transport
CA266_14265	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CA266_14270	COG2026	Addiction module toxin, RelE StbE family
CA266_14280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CA266_14285	COG4160	amino acid transport
CA266_14290	COG4215	(ABC) transporter
CA266_14295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CA266_14300	COG1126	abc transporter atp-binding protein
CA266_14310	COG0393	Putative heavy-metal-binding
CA266_14320	COG3023	N-Acetylmuramoyl-L-alanine amidase
CA266_14325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CA266_14330	COG0702	epimerase
CA266_14340	COG1737	Transcriptional regulator
CA266_14345	COG2190	(PTS) system
CA266_14345	COG1263	PTS System
CA266_14345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CA266_14350	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CA266_14355	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CA266_14360	COG0028	Belongs to the TPP enzyme family
CA266_14365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CA266_14370	COG1151	hydroxylamine reductase activity
CA266_14375	COG2431	L-lysine efflux transmembrane transporter activity
CA266_14380	COG3593	DNA synthesis involved in DNA repair
CA266_14385	COG2990	Protein conserved in bacteria
CA266_14390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CA266_14400	COG1278	Cold shock
CA266_14405	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CA266_14410	COG0542	response to heat
CA266_14415	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CA266_14420	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CA266_14425	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CA266_14435	COG0492	ferredoxin-NADP+ reductase activity
CA266_14445	COG3107	peptidoglycan biosynthetic process
CA266_14445	COG1674	ftsk spoiiie
CA266_14450	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CA266_14455	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CA266_14460	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CA266_14470	COG2814	Major facilitator Superfamily
CA266_14475	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CA266_14480	COG1882	Formate acetyltransferase
CA266_14485	COG2116	formate transmembrane transporter activity
CA266_14490	COG1944	ATP diphosphatase activity
CA266_14495	COG0252	asparaginase activity
CA266_14500	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CA266_14505	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CA266_14510	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CA266_14515	COG0539	negative regulation of cytoplasmic translation
CA266_14525	COG2333	competence protein COMEC
CA266_14525	COG0658	competence protein
CA266_14530	COG1132	(ABC) transporter
CA266_14535	COG1663	tetraacyldisaccharide 4'-kinase activity
CA266_14540	COG5383	Protein conserved in bacteria
CA266_14550	COG1278	Cold shock
CA266_14555	COG3214	Protein conserved in bacteria
CA266_14560	COG2835	tetraacyldisaccharide 4'-kinase activity
CA266_14565	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CA266_14570	COG3173	Aminoglycoside phosphotransferase
CA266_14575	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CA266_14580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CA266_14585	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
CA266_14595	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CA266_14600	COG2989	Protein conserved in bacteria
CA266_14605	COG3108	Peptidase M15
CA266_14610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CA266_14615	COG1448	Aminotransferase
CA266_14625	COG0017	Asparaginyl-tRNA synthetase
CA266_14630	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CA266_14635	COG3706	GGDEF domain
CA266_14640	COG0308	aminopeptidase N
CA266_14650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CA266_14655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CA266_14660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CA266_14665	COG0431	NADPH-dependent FMN reductase
CA266_14670	COG0167	dihydroorotate dehydrogenase activity
CA266_14680	COG3217	Mosc domain protein beta barrel domain protein
CA266_14680	COG0633	Ferredoxin
CA266_14685	COG0116	Belongs to the methyltransferase superfamily
CA266_14685	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CA266_14690	COG0488	(ABC) transporter
CA266_14695	COG2995	paraquat-inducible protein a
CA266_14700	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CA266_14700	COG3008	intermembrane lipid transfer
CA266_14705	COG3009	Protein conserved in bacteria
CA266_14710	COG3130	regulation of translation
CA266_14715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CA266_14725	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CA266_14730	COG1067	ATP-dependent peptidase activity
CA266_14750	COG3070	regulator of competence-specific genes
CA266_14755	COG1289	transmembrane transporter activity
CA266_14760	COG3304	Inner membrane component domain
CA266_14765	COG0210	DNA helicase
CA266_14770	COG1803	Methylglyoxal synthase
CA266_14780	COG1832	CoA-binding protein
CA266_14785	COG3785	DNA binding
CA266_14790	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CA266_14800	COG3594	Acyltransferase
CA266_14805	COG1254	Belongs to the acylphosphatase family
CA266_14810	COG2920	part of a sulfur-relay system
CA266_14815	COG0670	Belongs to the BI1 family
CA266_14840	COG2197	response regulator
CA266_14850	COG3121	Chaperone
CA266_14855	COG3188	usher protein
CA266_14865	COG0789	Transcriptional regulator
CA266_14870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CA266_14875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CA266_14890	COG0655	NAD(P)H dehydrogenase (quinone) activity
CA266_14895	COG1280	lysine exporter protein (LysE YggA)
CA266_14920	COG1113	amino acid transport
CA266_14935	COG2271	Major facilitator Superfamily
CA266_14960	COG2814	Major facilitator Superfamily
CA266_14965	COG0156	8-amino-7-oxononanoate synthase activity
CA266_14970	COG0183	Belongs to the thiolase family
CA266_14975	COG1250	3-hydroxyacyl-CoA dehydrogenase
CA266_14980	COG2197	response regulator
CA266_14985	COG0589	response to stress
CA266_15000	COG0531	amino acid
CA266_15005	COG1012	belongs to the aldehyde dehydrogenase family
CA266_15010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CA266_15060	COG3136	membrane protein required for alginate biosynthesis
CA266_15070	COG2197	response regulator
CA266_15075	COG0322	excinuclease ABC activity
CA266_15125	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CA266_15160	COG1538	Outer membrane efflux protein
CA266_15170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CA266_15175	COG0322	excinuclease ABC activity
CA266_15215	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CA266_15220	COG2943	transferase activity, transferring hexosyl groups
CA266_15225	COG5645	(Lipo)protein
CA266_15240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CA266_15250	COG0640	Transcriptional regulator
CA266_15265	COG0346	lactoylglutathione lyase activity
CA266_15275	COG2814	Major facilitator Superfamily
CA266_15285	COG1560	Kdo2-lipid A biosynthetic process
CA266_15295	COG1054	Belongs to the UPF0176 family
CA266_15300	COG2353	YceI-like domain
CA266_15305	COG3038	cytochrome b561
CA266_15310	COG0628	permease
CA266_15350	COG0418	dihydroorotase activity
CA266_15355	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CA266_15360	COG1530	ribonuclease E activity
CA266_15365	COG0564	pseudouridine synthase activity
CA266_15375	COG1399	metal-binding, possibly nucleic acid-binding protein
CA266_15380	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CA266_15385	COG0416	fatty acid biosynthetic process
CA266_15390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CA266_15395	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CA266_15405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CA266_15410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CA266_15415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CA266_15420	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CA266_15425	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CA266_15430	COG0470	DNA polymerase III
CA266_15435	COG0084	hydrolase, TatD family'
CA266_15440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CA266_15440	COG1263	PTS System
CA266_15450	COG1321	iron dependent repressor
CA266_15455	COG1914	H( )-stimulated, divalent metal cation uptake system
CA266_15465	COG1028	Short-chain dehydrogenase reductase Sdr
CA266_15470	COG1733	regulation of RNA biosynthetic process
CA266_15475	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CA266_15480	COG0537	adenosine 5'-monophosphoramidase activity
CA266_15485	COG5633	Lipoprotein
CA266_15490	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
CA266_15495	COG0510	thiamine kinase activity
CA266_15505	COG3150	esterase
CA266_15510	COG1252	NADH dehydrogenase
CA266_15515	COG3134	Outer membrane lipoprotein
CA266_15530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CA266_15535	COG2207	Transcriptional regulator
CA266_15535	COG3708	Transcriptional regulator
CA266_15565	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CA266_15570	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CA266_15575	COG3381	protein complex oligomerization
CA266_15580	COG2979	Protein of unknown function (DUF533)
CA266_15585	COG1770	oligopeptidase
CA266_15590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CA266_15595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CA266_15625	COG1528	Iron-storage protein
CA266_15630	COG2372	response to copper ion
CA266_15635	COG1276	copper resistance
CA266_15670	COG2249	NAD(P)H dehydrogenase (quinone) activity
CA266_15700	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CA266_15720	COG4565	transcriptional regulatory protein
CA266_15725	COG3290	protein histidine kinase activity
CA266_15740	COG1129	ABC transporter
CA266_15745	COG1172	Belongs to the binding-protein-dependent transport system permease family
CA266_15760	COG1464	Belongs to the NlpA lipoprotein family
CA266_15770	COG0589	response to stress
CA266_15775	COG0640	Transcriptional regulator
CA266_15785	COG0740	serine-type endopeptidase activity
CA266_15810	COG3121	Chaperone
CA266_15845	COG0012	GTP binding
CA266_15850	COG0659	secondary active sulfate transmembrane transporter activity
CA266_15855	COG0193	aminoacyl-tRNA hydrolase activity
CA266_15865	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CA266_15870	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CA266_15875	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CA266_15880	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CA266_15885	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CA266_15890	COG2890	protein-(glutamine-N5) methyltransferase activity
CA266_15895	COG3094	Invasion gene expression up-regulator, SirB
CA266_15900	COG2912	Transglutaminase-like superfamily
CA266_15905	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CA266_15910	COG0659	secondary active sulfate transmembrane transporter activity
CA266_15915	COG4702	Belongs to the UPF0303 family
CA266_15920	COG3706	GGDEF domain
CA266_15925	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CA266_15935	COG4591	ABC-type transport system involved in lipoprotein release permease component
CA266_15945	COG4591	ABC-type transport system involved in lipoprotein release permease component
CA266_15975	COG1486	melibiose metabolic process
CA266_15980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CA266_15980	COG1263	PTS System
CA266_15985	COG1177	transmembrane transport
CA266_16005	COG2195	Cleaves the N-terminal amino acid of tripeptides
CA266_16025	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CA266_16030	COG2850	peptidyl-arginine hydroxylation
CA266_16040	COG0745	RESPONSE REGULATOR receiver
CA266_16045	COG1397	ADP-ribosylglycohydrolase
CA266_16050	COG2188	Transcriptional regulator
CA266_16065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CA266_16070	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CA266_16075	COG2915	High frequency lysogenization protein hflD homolog
CA266_16085	COG0482	sulfurtransferase activity
CA266_16100	COG1187	pseudouridine synthase activity
CA266_16105	COG0538	isocitrate dehydrogenase activity
CA266_16120	COG3064	Membrane
CA266_16170	COG1609	Transcriptional regulator
CA266_16180	COG0673	inositol 2-dehydrogenase activity
CA266_16210	COG1278	Cold shock
CA266_16220	COG1335	isochorismatase
CA266_16225	COG0589	response to stress
CA266_16230	COG1028	Short-chain dehydrogenase reductase Sdr
CA266_16235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CA266_16240	COG1012	belongs to the aldehyde dehydrogenase family
CA266_16245	COG1917	Cupin 2, conserved barrel domain protein
CA266_16245	COG1396	sequence-specific DNA binding
CA266_16250	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CA266_16255	COG0174	glutamine synthetase
CA266_16260	COG0531	amino acid
CA266_16295	COG1605	Chorismate mutase
CA266_16310	COG1228	amidohydrolase
CA266_16320	COG0402	S-adenosylhomocysteine deaminase activity
CA266_16340	COG2211	Major facilitator Superfamily
CA266_16345	COG0477	Major facilitator Superfamily
CA266_16350	COG0583	DNA-binding transcription factor activity
CA266_16360	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CA266_16365	COG3493	citrate carrier protein
CA266_16430	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CA266_16430	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CA266_16435	COG3008	intermembrane lipid transfer
CA266_16440	COG2995	paraquat-inducible protein a
CA266_16445	COG1956	GAF domain-containing protein
CA266_16450	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CA266_16455	COG0793	Belongs to the peptidase S41A family
CA266_16460	COG0501	Belongs to the peptidase M48B family
CA266_16470	COG2814	Major facilitator Superfamily
CA266_16500	COG2188	Transcriptional regulator
CA266_16515	COG1823	symporter activity
CA266_16520	COG1988	membrane-bound metal-dependent
CA266_16525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CA266_16540	COG3001	Fructosamine kinase
CA266_16545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CA266_16550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CA266_16555	COG1121	(ABC) transporter
CA266_16560	COG0803	Belongs to the bacterial solute-binding protein 9 family
CA266_16590	COG0814	amino acid
CA266_16615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CA266_16625	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CA266_16630	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CA266_16640	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CA266_16660	COG4139	cobalamin transport
CA266_16665	COG0386	Belongs to the glutathione peroxidase family
CA266_16670	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CA266_16675	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CA266_16680	COG1215	transferase activity, transferring glycosyl groups
CA266_16685	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CA266_16685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CA266_16690	COG0726	polysaccharide deacetylase
CA266_16695	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CA266_16700	COG2076	Multidrug Resistance protein
CA266_16705	COG2076	Multidrug Resistance protein
CA266_16710	COG0791	NLP P60 protein
CA266_16715	COG0095	Lipoate-protein ligase
CA266_16735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CA266_16740	COG4558	Periplasmic binding protein
CA266_16745	COG3720	iron ion transport
CA266_16760	COG0386	Belongs to the glutathione peroxidase family
CA266_16765	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CA266_16770	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CA266_16775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CA266_16775	COG0574	Belongs to the PEP-utilizing enzyme family
CA266_16785	COG0628	permease
CA266_16790	COG0247	lactate metabolic process
CA266_16790	COG0277	FAD linked oxidase domain protein
CA266_16795	COG2050	protein possibly involved in aromatic compounds catabolism
CA266_16805	COG0316	Belongs to the HesB IscA family
CA266_16810	COG0719	Fe-S assembly protein
CA266_16815	COG0396	ATPase activity
CA266_16820	COG0719	Fe-S assembly protein
CA266_16825	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CA266_16830	COG2166	iron-sulfur cluster assembly
CA266_16835	COG1376	ErfK ybiS ycfS ynhG family protein
CA266_16835	COG1388	LysM domain
CA266_16845	COG0469	pyruvate kinase activity
CA266_16870	COG0534	Mate efflux family protein
CA266_16875	COG0307	riboflavin synthase, alpha
CA266_16885	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CA266_16890	COG2814	Major facilitator Superfamily
CA266_16895	COG0583	DNA-binding transcription factor activity
CA266_16900	COG1609	Transcriptional regulator
CA266_16915	COG0791	NLP P60 protein
CA266_16920	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CA266_16930	COG0346	lactoylglutathione lyase activity
CA266_16935	COG1902	pentaerythritol trinitrate reductase activity
CA266_16940	COG1309	transcriptional regulator
CA266_16945	COG2194	sulfuric ester hydrolase activity
CA266_16955	COG0583	DNA-binding transcription factor activity
CA266_16960	COG3313	Fe-S protein
CA266_16965	COG4989	oxidoreductase activity
CA266_16970	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CA266_16980	COG1289	transmembrane transporter activity
CA266_16985	COG1566	PFAM secretion protein HlyD family protein
CA266_16995	COG1846	Transcriptional regulator
CA266_17000	COG3133	Outer membrane lipoprotein
CA266_17005	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CA266_17015	COG0259	pyridoxamine-phosphate oxidase activity
CA266_17020	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CA266_17040	COG0625	glutathione transferase activity
CA266_17055	COG1418	mRNA catabolic process
CA266_17090	COG3135	benzoate transporter
CA266_17095	COG1396	sequence-specific DNA binding
CA266_17100	COG1505	serine-type exopeptidase activity
CA266_17105	COG3104	oligopeptide transport
CA266_17110	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CA266_17120	COG4659	FMN binding
CA266_17130	COG3708	Transcriptional regulator
CA266_17130	COG2207	Transcriptional regulator
CA266_17135	COG4656	Part of a membrane complex involved in electron transport
CA266_17140	COG2878	Part of a membrane complex involved in electron transport
CA266_17145	COG4657	Part of a membrane complex involved in electron transport
CA266_17155	COG0673	inositol 2-dehydrogenase activity
CA266_17160	COG0385	Bile acid
CA266_17170	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CA266_17175	COG1349	DNA-binding transcription factor activity
CA266_17180	COG0494	nUDIX hydrolase
CA266_17190	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CA266_17195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CA266_17195	COG1263	PTS System
CA266_17200	COG1609	Transcriptional regulator
CA266_17215	COG0583	DNA-binding transcription factor activity
CA266_17225	COG5339	Protein conserved in bacteria
CA266_17240	COG0114	fumarate hydratase activity
CA266_17260	COG1472	Belongs to the glycosyl hydrolase 3 family
CA266_17265	COG1649	PFAM Uncharacterised BCR, COG1649
CA266_17270	COG2814	Major facilitator Superfamily
CA266_17275	COG0583	DNA-binding transcription factor activity
CA266_17280	COG1940	carbohydrate kinase activity
CA266_17285	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CA266_17295	COG0789	Transcriptional regulator
CA266_17325	COG0477	Major facilitator Superfamily
CA266_17340	COG1742	UPF0060 membrane protein
CA266_17345	COG4221	oxidoreductase activity
CA266_17355	COG4772	TonB-dependent receptor
CA266_17360	COG3712	iron ion homeostasis
CA266_17365	COG1595	DNA-templated transcription, initiation
CA266_17370	COG0402	S-adenosylhomocysteine deaminase activity
CA266_17435	COG0339	signal peptide processing
CA266_17440	COG2271	Major facilitator Superfamily
CA266_17445	COG1335	isochorismatase
CA266_17450	COG3473	Maleate cis-trans isomerase
CA266_17455	COG0596	Alpha beta hydrolase
CA266_17460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CA266_17465	COG2309	aminopeptidase activity
CA266_17470	COG1846	Transcriptional regulator
CA266_17475	COG2080	2 iron, 2 sulfur cluster binding
CA266_17480	COG2010	Cytochrome c
CA266_17480	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CA266_17540	COG2140	Oxalate decarboxylase
CA266_17545	COG2190	(PTS) system
CA266_17545	COG1263	PTS System
CA266_17545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CA266_17550	COG2723	6-phospho-beta-galactosidase activity
CA266_17555	COG3711	transcriptional antiterminator
CA266_17590	COG0596	Alpha beta hydrolase
CA266_17640	COG1917	Cupin 2, conserved barrel domain protein
CA266_17640	COG2169	Transcriptional regulator
CA266_17660	COG2814	Major facilitator Superfamily
CA266_17665	COG1335	isochorismatase
CA266_17690	COG0768	penicillin binding
CA266_17705	COG0840	transmembrane signaling receptor activity
CA266_17730	COG1126	abc transporter atp-binding protein
CA266_17735	COG0765	amino acid transport
CA266_17745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CA266_17750	COG2079	MmgE PrpD family protein
CA266_17765	COG2814	Major facilitator Superfamily
CA266_17775	COG1349	DNA-binding transcription factor activity
CA266_17780	COG0673	inositol 2-dehydrogenase activity
CA266_17785	COG2814	Major facilitator Superfamily
CA266_17810	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CA266_17815	COG2862	Uncharacterized protein family, UPF0114
CA266_17820	COG2814	Major facilitator Superfamily
CA266_17825	COG0583	DNA-binding transcription factor activity
CA266_17835	COG0446	pyridine nucleotide-disulphide oxidoreductase
CA266_17850	COG1064	alcohol dehydrogenase
CA266_17860	COG3284	Transcriptional regulator
CA266_17870	COG2814	Major facilitator Superfamily
CA266_17875	COG5001	Diguanylate cyclase
CA266_17875	COG3300	MHYT domain
CA266_17930	COG0583	DNA-binding transcription factor activity
CA266_17940	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CA266_17950	COG0076	glutamate decarboxylase activity
CA266_17955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CA266_17965	COG0789	Transcriptional regulator
CA266_17970	COG0148	phosphopyruvate hydratase activity
CA266_17980	COG1227	inorganic diphosphatase activity
CA266_17985	COG5002	protein histidine kinase activity
CA266_17985	COG3447	MASE1 domain protein
CA266_17985	COG5001	Diguanylate cyclase
CA266_18000	COG0583	DNA-binding transcription factor activity
CA266_18025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CA266_18030	COG0702	epimerase
CA266_18035	COG0583	DNA-binding transcription factor activity
CA266_18060	COG4221	oxidoreductase activity
CA266_18065	COG4221	oxidoreductase activity
CA266_18080	COG1082	Xylose isomerase domain protein TIM barrel
CA266_18085	COG0673	inositol 2-dehydrogenase activity
CA266_18130	COG0300	oxidoreductase activity
CA266_18135	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CA266_18145	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CA266_18150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CA266_18155	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CA266_18195	COG2249	NAD(P)H dehydrogenase (quinone) activity
CA266_18205	COG2249	NAD(P)H dehydrogenase (quinone) activity
CA266_18210	COG1733	regulation of RNA biosynthetic process
CA266_18215	COG0477	Major facilitator Superfamily
CA266_18230	COG2382	esterase
CA266_18235	COG4774	siderophore transport
CA266_18245	COG1113	amino acid transport
CA266_18250	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CA266_18255	COG0318	PFAM AMP-dependent synthetase and ligase
CA266_18260	COG0693	protein deglycase activity
CA266_18275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CA266_18300	COG2957	Belongs to the agmatine deiminase family
CA266_18305	COG0583	DNA-binding transcription factor activity
CA266_18315	COG0243	molybdopterin cofactor binding
CA266_18335	COG0778	Nitroreductase
CA266_18340	COG2010	Cytochrome c
CA266_18340	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CA266_18345	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CA266_18345	COG2010	Cytochrome c
CA266_18350	COG2080	2 iron, 2 sulfur cluster binding
CA266_18365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CA266_18370	COG1737	Transcriptional regulator
CA266_18375	COG2723	6-phospho-beta-galactosidase activity
CA266_18380	COG3048	D-serine ammonia-lyase activity
CA266_18395	COG5507	3-demethylubiquinone-9 3-methyltransferase
CA266_18400	COG2199	diguanylate cyclase activity
CA266_18420	COG3264	Mechanosensitive ion channel
CA266_18420	COG1196	nuclear chromosome segregation
CA266_18425	COG0488	(ABC) transporter
CA266_18440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CA266_18450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CA266_18465	COG2239	Acts as a magnesium transporter
CA266_18505	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CA266_18510	COG0697	spore germination
CA266_18545	COG0583	DNA-binding transcription factor activity
CA266_18615	COG0306	phosphate transporter
CA266_18635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CA266_18655	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CA266_18660	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CA266_18690	COG1175	transmembrane transport
CA266_18695	COG0395	ABC-type sugar transport system, permease component
CA266_18700	COG3842	ATPase activity
CA266_18705	COG0673	inositol 2-dehydrogenase activity
CA266_18710	COG1940	carbohydrate kinase activity
CA266_18715	COG1349	DNA-binding transcription factor activity
CA266_18720	COG2222	sugar isomerase
CA266_18735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CA266_18745	COG0589	response to stress
CA266_18750	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CA266_18755	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CA266_18765	COG0531	amino acid
CA266_18780	COG1028	Short-chain dehydrogenase reductase Sdr
CA266_18785	COG0745	RESPONSE REGULATOR receiver
CA266_18790	COG2205	protein histidine kinase activity
CA266_18795	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CA266_18800	COG2267	carboxylic ester hydrolase activity
CA266_18810	COG3591	Belongs to the peptidase S1B family
CA266_18820	COG2814	Major facilitator Superfamily
CA266_18825	COG1643	Atp-dependent helicase
CA266_18830	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CA266_18835	COG3784	Protein of unknown function (DUF1318)
CA266_18845	COG2911	Protein conserved in bacteria
CA266_18850	COG0583	DNA-binding transcription factor activity
CA266_18860	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CA266_18865	COG3187	Heat shock protein
CA266_18870	COG3042	response to heat
CA266_18880	COG0674	pyruvate-flavodoxin oxidoreductase activity
CA266_18880	COG1013	pyruvate-flavodoxin oxidoreductase activity
CA266_18880	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CA266_18880	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA266_18885	COG0037	tRNA processing
CA266_18915	COG4166	transmembrane transport
CA266_18925	COG2866	Carboxypeptidase
CA266_18930	COG4948	Mandelate Racemase Muconate Lactonizing
CA266_18935	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CA266_18945	COG3768	UPF0283 membrane protein
CA266_18950	COG3106	COG3106 Predicted ATPase
CA266_18960	COG1983	PspC domain protein
CA266_18970	COG1842	Phage shock protein A
CA266_18975	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CA266_18990	COG1469	GTP cyclohydrolase I activity
CA266_19005	COG4171	peptide transport system, permease
CA266_19010	COG4172	Belongs to the ABC transporter superfamily
CA266_19015	COG4172	Belongs to the ABC transporter superfamily
CA266_19025	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CA266_19025	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CA266_19045	COG0243	molybdopterin cofactor binding
CA266_19050	COG0583	DNA-binding transcription factor activity
CA266_19060	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CA266_19065	COG0477	Major facilitator Superfamily
CA266_19070	COG1473	amidohydrolase
CA266_19075	COG1966	Carbon starvation protein
CA266_19080	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CA266_19085	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CA266_19090	COG1882	Formate acetyltransferase
CA266_19095	COG1349	DNA-binding transcription factor activity
CA266_19105	COG0023	Translation Initiation Factor
CA266_19125	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CA266_19130	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CA266_19135	COG0671	phosphoesterase, PA-phosphatase related
CA266_19145	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CA266_19160	COG0583	DNA-binding transcription factor activity
CA266_19175	COG0616	signal peptide processing
CA266_19180	COG1028	Short-chain dehydrogenase reductase Sdr
CA266_19185	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CA266_19190	COG1187	pseudouridine synthase activity
CA266_19205	COG0009	L-threonylcarbamoyladenylate synthase
CA266_19210	COG0613	PHP domain protein
CA266_19225	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CA266_19235	COG0133	tryptophan synthase activity
CA266_19240	COG0159	tryptophan synthase activity
CA266_19255	COG0727	PFAM Uncharacterised protein family (UPF0153)
CA266_19270	COG2917	probably involved in intracellular septation
CA266_19275	COG1607	acyl-coa hydrolase
CA266_19285	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CA266_19290	COG2350	Protein conserved in bacteria
CA266_19295	COG0583	DNA-binding transcription factor activity
CA266_19305	COG1609	Transcriptional regulator
CA266_19320	COG1070	Carbohydrate kinase
CA266_19325	COG1129	ABC transporter
CA266_19330	COG1172	Belongs to the binding-protein-dependent transport system permease family
CA266_19335	COG1879	ABC-type sugar transport system periplasmic component
CA266_19350	COG0783	Belongs to the Dps family
CA266_19360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CA266_19365	COG3099	Belongs to the UPF0263 family
CA266_19375	COG0444	Belongs to the ABC transporter superfamily
CA266_19380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CA266_19395	COG4166	transmembrane transport
CA266_19400	COG2095	MarC family integral membrane protein
CA266_19405	COG1454	alcohol dehydrogenase
CA266_19405	COG1012	belongs to the aldehyde dehydrogenase family
CA266_19430	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CA266_19435	COG0745	RESPONSE REGULATOR receiver
CA266_19440	COG1752	Esterase of the alpha-beta hydrolase superfamily
CA266_19445	COG3012	SEC-C Motif Domain Protein
CA266_19450	COG0788	formyltetrahydrofolate deformylase activity
CA266_19470	COG0708	Exodeoxyribonuclease III
CA266_19475	COG0494	nUDIX hydrolase
CA266_19485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CA266_19490	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CA266_19500	COG0778	Nitroreductase
CA266_19505	COG0616	signal peptide processing
CA266_19510	COG0252	asparaginase activity
CA266_19515	COG1335	isochorismatase
CA266_19525	COG3139	Protein of unknown function (DUF1315)
CA266_19530	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CA266_19545	COG3713	MltA-interacting MipA family protein
CA266_19555	COG2766	serine protein kinase
CA266_19560	COG2718	Belongs to the UPF0229 family
CA266_19600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CA266_19605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CA266_19615	COG3443	Belongs to the bacterial solute-binding protein 9 family
CA266_19620	COG2719	SpoVR family
CA266_19625	COG2186	Transcriptional regulator
CA266_19630	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CA266_19635	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CA266_19645	COG2983	Belongs to the UPF0260 family
CA266_19650	COG0179	Fumarylacetoacetate (FAA) hydrolase
CA266_19655	COG2951	lytic endotransglycosylase activity
CA266_19660	COG3100	YcgL domain-containing protein
CA266_19665	COG0850	regulation of cytokinetic process
CA266_19670	COG2894	cell division
CA266_19675	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CA266_19680	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CA266_19685	COG0318	PFAM AMP-dependent synthetase and ligase
CA266_19690	COG3065	identical protein binding
CA266_19700	COG1199	ATP-dependent helicase activity
CA266_19705	COG0251	oxidation-reduction process
CA266_19710	COG2076	Multidrug Resistance protein
CA266_19715	COG2076	Multidrug Resistance protein
CA266_19720	COG0800	Aldolase
CA266_19725	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CA266_19730	COG1737	Transcriptional regulator
CA266_19745	COG1560	Kdo2-lipid A biosynthetic process
CA266_19750	COG0739	heme binding
CA266_19755	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CA266_19760	COG1121	(ABC) transporter
CA266_19765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CA266_19770	COG2255	four-way junction helicase activity
CA266_19775	COG0632	four-way junction helicase activity
CA266_19780	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CA266_19785	COG0217	transcriptional regulatory protein
CA266_19790	COG0494	nUDIX hydrolase
CA266_19795	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CA266_19805	COG1335	isochorismatase
CA266_19810	COG1801	Protein of unknown function DUF72
CA266_19815	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CA266_19820	COG2226	methyltransferase
CA266_19825	COG0500	methyltransferase
CA266_19830	COG0545	Peptidyl-prolyl cis-trans isomerase
CA266_19840	COG3142	Participates in the control of copper homeostasis
CA266_19845	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CA266_19850	COG3102	Protein conserved in bacteria
CA266_19855	COG0018	arginyl-trna synthetase
CA266_19865	COG0673	inositol 2-dehydrogenase activity
CA266_19870	COG3132	Protein of unknown function, DUF480
CA266_19875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CA266_19880	COG0477	Major facilitator Superfamily
CA266_19890	COG2999	glutathione oxidoreductase activity
CA266_19910	COG3097	Belongs to the UPF0267 family
CA266_19915	COG3141	response to X-ray
CA266_19920	COG0513	Belongs to the DEAD box helicase family
CA266_19930	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CA266_19935	COG3140	Belongs to the UPF0181 family
CA266_19940	COG1216	Glycosyl transferase, family 2
CA266_19950	COG0494	nUDIX hydrolase
CA266_19955	COG1760	l-serine dehydratase
CA266_19960	COG2200	EAL domain
CA266_19965	COG1253	flavin adenine dinucleotide binding
CA266_19970	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CA266_19970	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CA266_19975	COG3715	PTS system
CA266_19980	COG3716	PTS system mannose fructose sorbose family IID component
CA266_19985	COG4811	Protein of unknown function (DUF986)
CA266_19990	COG1971	Probably functions as a manganese efflux pump
CA266_19995	COG2226	methyltransferase
CA266_20000	COG1496	oxidoreductase activity
CA266_20030	COG1113	amino acid transport
CA266_20075	COG2207	Transcriptional regulator
CA266_20100	COG1652	LysM domain
CA266_20120	COG2988	succinylglutamate desuccinylase activity
CA266_20125	COG3724	N-succinylarginine dihydrolase activity
CA266_20130	COG1012	belongs to the aldehyde dehydrogenase family
CA266_20135	COG3138	arginine N-succinyltransferase
CA266_20140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CA266_20150	COG4608	Belongs to the ABC transporter superfamily
CA266_20155	COG0444	Belongs to the ABC transporter superfamily
CA266_20165	COG0601	transmembrane transport
CA266_20175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CA266_20180	COG1271	oxidase subunit
CA266_20185	COG1294	oxidase, subunit
CA266_20235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CA266_20240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CA266_20245	COG2181	nitrate reductase activity
CA266_20250	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CA266_20255	COG1140	nitrate reductase beta subunit
CA266_20260	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CA266_20310	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CA266_20315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CA266_20320	COG3710	Transcriptional regulator
CA266_20325	COG2223	nitrite transmembrane transporter activity
CA266_20330	COG3850	Histidine kinase
CA266_20335	COG2197	response regulator
CA266_20340	COG4932	domain protein
CA266_20345	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CA266_20355	COG0747	negative chemotaxis
CA266_20360	COG4608	Belongs to the ABC transporter superfamily
CA266_20365	COG0444	Belongs to the ABC transporter superfamily
CA266_20370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CA266_20375	COG0601	transmembrane transport
CA266_20385	COG0583	DNA-binding transcription factor activity
CA266_20390	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CA266_20395	COG4572	Cation transport regulator
CA266_20400	COG2375	cellular response to nickel ion
CA266_20405	COG0387	Pfam Sodium calcium exchanger
CA266_20415	COG1702	phosphate starvation-inducible protein PhoH
CA266_20425	COG2822	iron ion transport
CA266_20430	COG0672	)-iron permease
CA266_20440	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CA266_20440	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CA266_20440	COG0506	proline dehydrogenase activity
CA266_20445	COG1126	abc transporter atp-binding protein
CA266_20450	COG0765	amino acid transport
CA266_20455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CA266_20460	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CA266_20470	COG1191	sigma factor activity
CA266_20480	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CA266_20505	COG0583	DNA-binding transcription factor activity
CA266_20515	COG1677	Flagellar hook-basal body complex protein FliE
CA266_20525	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CA266_20530	COG1317	bacterial-type flagellum organization
CA266_20535	COG1157	protein secretion by the type III secretion system
CA266_20540	COG2882	bacterial-type flagellum organization
CA266_20595	COG1256	bacterial-type flagellum assembly
CA266_20630	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CA266_20635	COG1558	bacterial-type flagellum-dependent cell motility
CA266_20640	COG1815	bacterial-type flagellum-dependent cell motility
CA266_20650	COG2747	anti-sigma28 factor FlgM
CA266_20655	COG3418	PFAM FlgN family protein
CA266_20675	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CA266_20680	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CA266_20685	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CA266_20690	COG0745	RESPONSE REGULATOR receiver
CA266_20700	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CA266_20705	COG0840	transmembrane signaling receptor activity
CA266_20710	COG0840	transmembrane signaling receptor activity
CA266_20715	COG0835	chemotaxis
CA266_20720	COG0643	Histidine kinase
CA266_20720	COG2198	Histidine kinase
CA266_20750	COG0589	response to stress
CA266_20755	COG2130	NADP-dependent
CA266_20760	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CA266_20935	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CA266_20940	COG3483	tryptophan 2,3-dioxygenase activity
CA266_20945	COG1609	Transcriptional regulator
CA266_20985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CA266_20990	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CA266_21015	COG3781	membrane
CA266_21020	COG2837	iron assimilation
CA266_21025	COG1393	Belongs to the ArsC family
CA266_21030	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CA266_21040	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CA266_21065	COG1285	pathogenesis
CA266_21075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CA266_21085	COG0076	glutamate decarboxylase activity
CA266_21120	COG1028	Short-chain dehydrogenase reductase Sdr
CA266_21120	COG0604	alcohol dehydrogenase
CA266_21120	COG3321	synthase
CA266_21135	COG3753	Protein conserved in bacteria
CA266_21140	COG2261	transglycosylase associated protein
CA266_21145	COG1560	Kdo2-lipid A biosynthetic process
CA266_21150	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CA266_21160	COG5001	Diguanylate cyclase
CA266_21160	COG4251	negative regulation of phosphorylation
CA266_21160	COG3706	GGDEF domain
CA266_21160	COG2203	Gaf domain
CA266_21170	COG2030	dehydratase
CA266_21170	COG1012	belongs to the aldehyde dehydrogenase family
CA266_21175	COG3396	Phenylacetate-CoA oxygenase
CA266_21180	COG3460	Phenylacetate-CoA oxygenase
CA266_21185	COG3396	Phenylacetate-CoA oxygenase
CA266_21190	COG2151	metal-sulfur cluster biosynthetic enzyme
CA266_21195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CA266_21200	COG1024	Enoyl-CoA hydratase
CA266_21205	COG1024	Enoyl-CoA hydratase
CA266_21210	COG1250	3-hydroxyacyl-CoA dehydrogenase
CA266_21215	COG2050	protein possibly involved in aromatic compounds catabolism
CA266_21220	COG0183	Belongs to the thiolase family
CA266_21225	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CA266_21230	COG3327	negative regulation of DNA-templated transcription, initiation
CA266_21235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CA266_21240	COG1113	amino acid transport
CA266_21245	COG1448	Aminotransferase
CA266_21260	COG0583	DNA-binding transcription factor activity
CA266_21265	COG0625	glutathione transferase activity
CA266_21290	COG4772	TonB-dependent receptor
CA266_21295	COG4993	Dehydrogenase
CA266_21305	COG0534	Mate efflux family protein
CA266_21350	COG3228	Belongs to the MtfA family
CA266_21360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CA266_21365	COG4977	sequence-specific DNA binding
CA266_21375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CA266_21380	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CA266_21385	COG1116	anion transmembrane transporter activity
CA266_21390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CA266_21395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CA266_21410	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CA266_21450	COG3238	Protein conserved in bacteria
CA266_21455	COG1247	-acetyltransferase
CA266_21475	COG0583	DNA-binding transcription factor activity
CA266_21490	COG2814	Major facilitator Superfamily
CA266_21500	COG2011	ABC-type metal ion transport system permease component
CA266_21520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CA266_21535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CA266_21540	COG4172	Belongs to the ABC transporter superfamily
CA266_21545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CA266_21555	COG0747	negative chemotaxis
CA266_21565	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CA266_21585	COG1028	Short-chain dehydrogenase reductase Sdr
CA266_21590	COG1169	isochorismate synthase
CA266_21605	COG0471	metal ion transport
CA266_21610	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CA266_21620	COG3051	citrate lyase alpha subunit
CA266_21625	COG2301	Belongs to the HpcH HpaI aldolase family
CA266_21630	COG3052	prosthetic group binding
CA266_21635	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CA266_21640	COG4565	transcriptional regulatory protein
CA266_21645	COG3250	beta-galactosidase activity
CA266_21655	COG0300	oxidoreductase activity
CA266_21660	COG2207	Transcriptional regulator
CA266_21675	COG2197	response regulator
CA266_21695	COG1012	belongs to the aldehyde dehydrogenase family
CA266_21700	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CA266_21735	COG2070	2-Nitropropane dioxygenase
CA266_21755	COG2271	Major facilitator Superfamily
CA266_21785	COG0411	ABC transporter
CA266_21835	COG0583	DNA-binding transcription factor activity
CA266_21845	COG0456	acetyltransferase
CA266_21860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CA266_21865	COG0156	8-amino-7-oxononanoate synthase activity
CA266_21870	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CA266_21875	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CA266_21880	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CA266_21885	COG2244	polysaccharide biosynthetic process
CA266_21895	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CA266_21900	COG0795	lipopolysaccharide-transporting ATPase activity
CA266_21925	COG0583	DNA-binding transcription factor activity
CA266_21940	COG1609	Transcriptional regulator
CA266_21950	COG3623	hexulose-6-phosphate isomerase
CA266_21955	COG1070	Carbohydrate kinase
CA266_21960	COG1172	Belongs to the binding-protein-dependent transport system permease family
CA266_21970	COG1879	ABC-type sugar transport system periplasmic component
CA266_21975	COG1063	alcohol dehydrogenase
CA266_21985	COG1473	amidohydrolase
CA266_21990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CA266_21995	COG2926	Belongs to the UPF0265 family
CA266_22000	COG1289	transmembrane transporter activity
CA266_22005	COG3023	N-Acetylmuramoyl-L-alanine amidase
CA266_22045	COG5301	cellulose 1,4-beta-cellobiosidase activity
CA266_22120	COG0740	serine-type endopeptidase activity
CA266_22160	COG3179	chitinase
CA266_22200	COG1061	Type III restriction enzyme res subunit
CA266_22290	COG2925	Exonuclease
CA266_22295	COG0531	amino acid
CA266_22300	COG0174	glutamine synthetase
CA266_22305	COG1396	sequence-specific DNA binding
CA266_22305	COG1917	Cupin 2, conserved barrel domain protein
CA266_22310	COG1129	ABC transporter
CA266_22315	COG1172	Belongs to the binding-protein-dependent transport system permease family
CA266_22320	COG4771	TonB-dependent receptor
CA266_22335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CA266_22345	COG0833	amino acid
CA266_22350	COG0583	DNA-binding transcription factor activity
CA266_22360	COG2855	membrane
CA266_22365	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CA266_22370	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CA266_22370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CA266_22370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CA266_22375	COG1105	Belongs to the carbohydrate kinase PfkB family
CA266_22385	COG0494	nUDIX hydrolase
CA266_22390	COG3005	denitrification pathway
CA266_22395	COG0243	molybdopterin cofactor binding
CA266_22415	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CA266_22420	COG1312	Catalyzes the dehydration of D-mannonate
CA266_22425	COG0246	Mannitol dehydrogenase
CA266_22435	COG0523	cobalamin synthesis protein
CA266_22440	COG0671	phosphoesterase, PA-phosphatase related
CA266_22525	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CA266_22530	COG0791	NLP P60 protein
CA266_22535	COG2200	EAL domain
CA266_22540	COG4166	transmembrane transport
CA266_22545	COG4174	ABC transporter (Permease)
CA266_22550	COG4239	(ABC) transporter, permease
CA266_22555	COG4172	Belongs to the ABC transporter superfamily
CA266_22565	COG2814	Major facilitator Superfamily
CA266_22570	COG1187	pseudouridine synthase activity
CA266_22575	COG1061	Type III restriction enzyme res subunit
CA266_22580	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CA266_22585	COG3081	Nucleoid-associated protein
CA266_22590	COG3082	Protein of unknown function (DUF1414)
CA266_22595	COG3083	sulfuric ester hydrolase activity
CA266_22610	COG0625	glutathione transferase activity
CA266_22625	COG2271	Major facilitator Superfamily
CA266_22665	COG5301	cellulose 1,4-beta-cellobiosidase activity
CA266_22765	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CA266_22780	COG0346	lactoylglutathione lyase activity
CA266_22795	COG2223	nitrite transmembrane transporter activity
CA266_22800	COG2198	Histidine kinase
CA266_22800	COG0642	Histidine kinase
CA266_22805	COG2197	response regulator
CA266_22810	COG2205	protein histidine kinase activity
CA266_22810	COG0784	Response regulator, receiver
CA266_22820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CA266_22825	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CA266_22835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CA266_22855	COG0814	amino acid
CA266_22870	COG0318	PFAM AMP-dependent synthetase and ligase
CA266_22880	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CA266_22885	COG0596	Alpha beta hydrolase
CA266_22890	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CA266_22895	COG4575	ribosome binding
CA266_22900	COG1063	alcohol dehydrogenase
CA266_22905	COG1028	Short-chain dehydrogenase reductase Sdr
CA266_22935	COG0028	Belongs to the TPP enzyme family
CA266_22940	COG0583	DNA-binding transcription factor activity
CA266_22945	COG1007	ATP synthesis coupled electron transport
CA266_22950	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA266_22955	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CA266_22960	COG0713	ATP synthesis coupled electron transport
CA266_22965	COG0839	Belongs to the complex I subunit 6 family
CA266_22975	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CA266_22980	COG1034	ATP synthesis coupled electron transport
CA266_22995	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA266_22995	COG0649	NAD binding
CA266_23000	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA266_23005	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA266_23010	COG0583	DNA-binding transcription factor activity
CA266_23015	COG0436	Aminotransferase
CA266_23020	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CA266_23025	COG0471	metal ion transport
CA266_23025	COG0490	domain, Protein
CA266_23030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CA266_23035	COG3013	Belongs to the UPF0304 family
CA266_23040	COG3092	negative regulation of chromosome organization
CA266_23045	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CA266_23050	COG0280	phosphate acetyltransferase
CA266_23050	COG0857	belongs to the CobB CobQ family
CA266_23065	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CA266_23070	COG3959	Transketolase, thiamine diphosphate binding domain
CA266_23075	COG3037	sugar-specific permease SgaT UlaA
CA266_23085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CA266_23090	COG1609	Transcriptional regulator
CA266_23095	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CA266_23100	COG0622	Phosphoesterase
CA266_23105	COG0625	glutathione transferase activity
CA266_23110	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CA266_23115	COG1090	epimerase
CA266_23120	COG4598	ABC transporter
CA266_23130	COG4215	(ABC) transporter
CA266_23135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CA266_23140	COG0163	prenyltransferase activity
CA266_23145	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CA266_23150	COG1286	toxin biosynthetic process
CA266_23155	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CA266_23160	COG0285	dihydrofolate synthase activity
CA266_23165	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CA266_23170	COG0586	Pfam SNARE associated Golgi protein
CA266_23180	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CA266_23185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CA266_23195	COG0697	spore germination
CA266_23200	COG0642	Histidine kinase
CA266_23240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CA266_23245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CA266_23285	COG2195	Cleaves the N-terminal amino acid of tripeptides
CA266_23290	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CA266_23305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CA266_23310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CA266_23310	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CA266_23320	COG3101	peptidyl-lysine hydroxylation
CA266_23325	COG0730	response to heat
CA266_23330	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CA266_23335	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CA266_23340	COG2890	protein-(glutamine-N5) methyltransferase activity
CA266_23345	COG2840	Smr protein MutS2
CA266_23350	COG2062	phosphohistidine phosphatase, SixA
CA266_23355	COG1024	Enoyl-CoA hydratase
CA266_23355	COG1250	3-hydroxyacyl-CoA dehydrogenase
CA266_23360	COG0183	Belongs to the thiolase family
CA266_23365	COG3691	Protein conserved in bacteria
CA266_23380	COG3088	subunit of a heme lyase
CA266_23380	COG4235	cytochrome complex assembly
CA266_23385	COG4235	cytochrome complex assembly
CA266_23385	COG3088	subunit of a heme lyase
CA266_23390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CA266_23395	COG1138	Cytochrome C-type biogenesis protein
CA266_23400	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CA266_23405	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CA266_23410	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CA266_23415	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CA266_23425	COG2116	formate transmembrane transporter activity
CA266_23435	COG2706	6-phosphogluconolactonase activity
CA266_23440	COG3708	Transcriptional regulator
CA266_23440	COG2207	Transcriptional regulator
CA266_23455	COG2197	response regulator
CA266_23465	COG0583	DNA-binding transcription factor activity
CA266_23475	COG0697	spore germination
CA266_23490	COG2951	lytic endotransglycosylase activity
CA266_23500	COG1598	PFAM Uncharacterised protein family UPF0150
CA266_23510	COG3038	cytochrome b561
CA266_23515	COG0436	Aminotransferase
CA266_23530	COG3275	phosphorelay sensor kinase activity
CA266_23535	COG3279	Response regulator of the LytR AlgR family
CA266_23545	COG2223	nitrite transmembrane transporter activity
CA266_23560	COG1794	racemase activity, acting on amino acids and derivatives
CA266_23575	COG3961	Belongs to the TPP enzyme family
CA266_23580	COG0667	Aldo Keto reductase
CA266_23590	COG1914	H( )-stimulated, divalent metal cation uptake system
CA266_23595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CA266_23610	COG2116	formate transmembrane transporter activity
CA266_23615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CA266_23645	COG4592	Periplasmic binding protein
CA266_23650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CA266_23655	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CA266_23660	COG1120	ATPase activity
CA266_23665	COG0747	negative chemotaxis
CA266_23685	COG4302	ethanolamine ammonia-lyase activity
CA266_23690	COG4303	Ethanolamine ammonia lyase large subunit
CA266_23705	COG0583	DNA-binding transcription factor activity
CA266_23710	COG0385	Bile acid
CA266_23715	COG3530	Putative quorum-sensing-regulated virulence factor
CA266_23720	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CA266_23725	COG3115	cell septum assembly
CA266_23730	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CA266_23740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CA266_23745	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CA266_23755	COG2205	protein histidine kinase activity
CA266_23760	COG0745	RESPONSE REGULATOR receiver
CA266_23775	COG4208	sulfate ABC transporter
CA266_23780	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CA266_23790	COG2837	iron assimilation
CA266_23805	COG3111	PFAM Bacterial OB fold (BOF) protein
CA266_23810	COG0456	acetyltransferase
CA266_23815	COG0860	N-Acetylmuramoyl-L-alanine amidase
CA266_23820	COG0408	coproporphyrinogen oxidase activity
CA266_23825	COG1671	Belongs to the UPF0178 family
CA266_23835	COG1770	oligopeptidase
CA266_24060	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CA266_24075	COG0741	lytic transglycosylase activity