locus-tag	class	description
BVG89_00025	COG3022	response to hydroperoxide
BVG89_00030	COG1115	amino acid carrier protein
BVG89_00035	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BVG89_00040	COG0521	Mo-molybdopterin cofactor biosynthetic process
BVG89_00050	COG1584	GPR1 FUN34 yaaH family protein
BVG89_00055	COG0443	Heat shock 70 kDa protein
BVG89_00060	COG0484	heat shock protein binding
BVG89_00065	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BVG89_00070	COG0583	DNA-binding transcription factor activity
BVG89_00075	COG0268	Binds directly to 16S ribosomal RNA
BVG89_00085	COG0196	riboflavin kinase activity
BVG89_00090	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BVG89_00095	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BVG89_00100	COG1047	Peptidyl-prolyl cis-trans
BVG89_00105	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BVG89_00110	COG0583	DNA-binding transcription factor activity
BVG89_00130	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BVG89_00135	COG0505	Belongs to the CarA family
BVG89_00140	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BVG89_00160	COG2966	Psort location CytoplasmicMembrane, score
BVG89_00170	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BVG89_00180	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BVG89_00185	COG2967	ApaG domain
BVG89_00190	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BVG89_00195	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BVG89_00200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BVG89_00205	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BVG89_00215	COG0564	pseudouridine synthase activity
BVG89_00220	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BVG89_00225	COG0417	DNA replication proofreading
BVG89_00230	COG0586	Pfam SNARE associated Golgi protein
BVG89_00235	COG0440	acetolactate synthase activity
BVG89_00240	COG0028	Belongs to the TPP enzyme family
BVG89_00255	COG1178	ABC-type Fe3 transport system permease component
BVG89_00260	COG4143	(ABC) transporter
BVG89_00275	COG2814	Major facilitator Superfamily
BVG89_00280	COG0471	metal ion transport
BVG89_00285	COG0066	3-isopropylmalate dehydratase activity
BVG89_00290	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BVG89_00295	COG0473	3-isopropylmalate dehydrogenase activity
BVG89_00300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BVG89_00305	COG0583	DNA-binding transcription factor activity
BVG89_00310	COG1022	Amp-dependent synthetase and ligase
BVG89_00315	COG0028	Belongs to the TPP enzyme family
BVG89_00325	COG1609	Transcriptional regulator
BVG89_00335	COG2001	Belongs to the MraZ family
BVG89_00340	COG0275	rRNA processing
BVG89_00345	COG3116	cell division
BVG89_00350	COG0768	penicillin binding
BVG89_00355	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BVG89_00360	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BVG89_00365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BVG89_00375	COG0772	Belongs to the SEDS family
BVG89_00380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BVG89_00385	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BVG89_00395	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BVG89_00400	COG0849	cell division
BVG89_00405	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BVG89_00425	COG0653	protein targeting
BVG89_00430	COG0494	nUDIX hydrolase
BVG89_00435	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BVG89_00440	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BVG89_00445	COG0237	dephospho-CoA kinase activity
BVG89_00450	COG0516	GMP reductase activity
BVG89_00455	COG1459	type II secretion system
BVG89_00460	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BVG89_00465	COG4969	Belongs to the N-Me-Phe pilin family
BVG89_00475	COG3023	N-Acetylmuramoyl-L-alanine amidase
BVG89_00480	COG3725	Membrane protein required for beta-lactamase induction
BVG89_00485	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BVG89_00495	COG0316	Belongs to the HesB IscA family
BVG89_00505	COG2860	membrane
BVG89_00515	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BVG89_00520	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BVG89_00525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVG89_00535	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BVG89_00540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BVG89_00545	COG3956	TIGRFAM MazG family protein
BVG89_00550	COG0504	CTP synthase activity
BVG89_00580	COG2986	histidine ammonia-lyase
BVG89_00590	COG2271	Major facilitator Superfamily
BVG89_00595	COG0602	queuosine metabolic process
BVG89_00605	COG0720	synthase
BVG89_00610	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BVG89_00615	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BVG89_00620	COG0175	sulfate reduction
BVG89_00625	COG2234	aminopeptidase activity
BVG89_00630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BVG89_00630	COG1648	precorrin-2 dehydrogenase activity
BVG89_00635	COG0175	sulfate reduction
BVG89_00640	COG2895	sulfate adenylyltransferase (ATP) activity
BVG89_00660	COG0765	amino acid transport
BVG89_00670	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BVG89_00675	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BVG89_00680	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BVG89_00685	COG0585	pseudouridine synthase activity
BVG89_00690	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BVG89_00695	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BVG89_00700	COG1388	LysM domain
BVG89_00700	COG4942	peptidase
BVG89_00705	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BVG89_00710	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BVG89_00730	COG0667	Aldo Keto reductase
BVG89_00745	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BVG89_00750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BVG89_00755	COG2723	6-phospho-beta-galactosidase activity
BVG89_00760	COG1917	Cupin 2, conserved barrel domain protein
BVG89_00760	COG2169	Transcriptional regulator
BVG89_00785	COG2137	regulation of response to DNA damage stimulus
BVG89_00790	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BVG89_00795	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BVG89_00825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BVG89_00830	COG1238	metal cluster binding
BVG89_00835	COG2918	glutathione biosynthetic process
BVG89_00845	COG4536	flavin adenine dinucleotide binding
BVG89_00850	COG4137	Cytochrome C assembly protein
BVG89_00855	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BVG89_00860	COG0228	four-way junction DNA binding
BVG89_00865	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BVG89_00875	COG0335	large ribosomal subunit rRNA binding
BVG89_00895	COG3137	Salt-induced outer membrane protein
BVG89_00900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BVG89_00905	COG0287	Prephenate dehydrogenase
BVG89_00905	COG1605	Chorismate mutase
BVG89_00910	COG0077	Prephenate dehydratase
BVG89_00910	COG1605	Chorismate mutase
BVG89_00915	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BVG89_00920	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BVG89_00930	COG0564	pseudouridine synthase activity
BVG89_00940	COG0542	response to heat
BVG89_00970	COG0656	L-ascorbic acid biosynthetic process
BVG89_00975	COG0583	DNA-binding transcription factor activity
BVG89_00980	COG2814	Major facilitator Superfamily
BVG89_00990	COG1388	LysM domain
BVG89_00990	COG0741	lytic transglycosylase activity
BVG89_00995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVG89_01000	COG2226	methyltransferase
BVG89_01005	COG0328	RNA-DNA hybrid ribonuclease activity
BVG89_01010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BVG89_01035	COG0436	Aminotransferase
BVG89_01040	COG0235	Class ii aldolase
BVG89_01045	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
BVG89_01050	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BVG89_01055	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BVG89_01060	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BVG89_01070	COG1960	acyl-CoA dehydrogenase activity
BVG89_01075	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BVG89_01080	COG0121	glutamine amidotransferase
BVG89_01085	COG3034	peptidoglycan biosynthetic process
BVG89_01090	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BVG89_01095	COG1805	sodium ion transport
BVG89_01100	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BVG89_01105	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BVG89_01110	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BVG89_01115	COG2871	sodium ion transport
BVG89_01120	COG1477	protein flavinylation
BVG89_01125	COG2991	Protein conserved in bacteria
BVG89_01130	COG0584	glycerophosphoryl diester phosphodiesterase
BVG89_01135	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BVG89_01140	COG2195	Cleaves the N-terminal amino acid of tripeptides
BVG89_01145	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BVG89_01175	COG3423	Transcriptional regulator
BVG89_01185	COG2314	TM2 domain
BVG89_01215	COG3038	cytochrome b561
BVG89_01220	COG0747	negative chemotaxis
BVG89_01225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVG89_01230	COG1733	regulation of RNA biosynthetic process
BVG89_01235	COG2249	NAD(P)H dehydrogenase (quinone) activity
BVG89_01250	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BVG89_01260	COG2207	Transcriptional regulator
BVG89_01265	COG1012	belongs to the aldehyde dehydrogenase family
BVG89_01275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BVG89_01275	COG2169	Transcriptional regulator
BVG89_01300	COG3961	Belongs to the TPP enzyme family
BVG89_01335	COG1349	DNA-binding transcription factor activity
BVG89_01340	COG0346	lactoylglutathione lyase activity
BVG89_01355	COG1335	isochorismatase
BVG89_01365	COG3011	Protein conserved in bacteria
BVG89_01375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVG89_01380	COG3416	Protein conserved in bacteria
BVG89_01390	COG2226	methyltransferase
BVG89_01395	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BVG89_01440	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BVG89_01460	COG1595	DNA-templated transcription, initiation
BVG89_01495	COG1414	Transcriptional regulator
BVG89_01510	COG4126	flavin adenine dinucleotide binding
BVG89_01515	COG3123	guanosine phosphorylase activity
BVG89_01520	COG2974	May be involved in recombination
BVG89_01525	COG1940	carbohydrate kinase activity
BVG89_01545	COG0419	ATPase involved in DNA repair
BVG89_01550	COG0420	3'-5' exonuclease activity
BVG89_01555	COG0745	RESPONSE REGULATOR receiver
BVG89_01560	COG5002	protein histidine kinase activity
BVG89_01570	COG1114	Component of the transport system for branched-chain amino acids
BVG89_01585	COG0668	transmembrane transport
BVG89_01590	COG0366	Alpha amylase catalytic
BVG89_01600	COG0450	alkyl hydroperoxide reductase
BVG89_01605	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
BVG89_01610	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BVG89_01615	COG0343	queuine tRNA-ribosyltransferase activity
BVG89_01620	COG1862	Preprotein translocase
BVG89_01630	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BVG89_01635	COG4238	major outer membrane lipoprotein
BVG89_01640	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BVG89_01645	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BVG89_01645	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BVG89_01650	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BVG89_01655	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BVG89_01660	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BVG89_01665	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BVG89_01670	COG0667	Aldo Keto reductase
BVG89_01675	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BVG89_01680	COG0142	geranyltranstransferase activity
BVG89_01685	COG1722	exodeoxyribonuclease VII activity
BVG89_01690	COG0301	tRNA thio-modification
BVG89_01690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BVG89_01695	COG0693	protein deglycase activity
BVG89_01700	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BVG89_01705	COG1666	GTP binding
BVG89_01710	COG2814	Major facilitator Superfamily
BVG89_01715	COG0109	protoheme IX farnesyltransferase activity
BVG89_01720	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BVG89_01725	COG1845	cytochrome c oxidase, subunit III
BVG89_01730	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BVG89_01735	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BVG89_01740	COG2223	nitrite transmembrane transporter activity
BVG89_01745	COG3056	Lipoprotein
BVG89_01750	COG0271	Belongs to the BolA IbaG family
BVG89_01755	COG0544	peptidyl-prolyl cis-trans isomerase activity
BVG89_01765	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BVG89_01770	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BVG89_01780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BVG89_01785	COG1555	photosystem II stabilization
BVG89_01790	COG0824	Thioesterase
BVG89_01795	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BVG89_01800	COG4533	DNA binding
BVG89_01805	COG0561	phosphatase activity
BVG89_01815	COG1522	sequence-specific DNA binding
BVG89_01820	COG1132	(ABC) transporter
BVG89_01825	COG1132	(ABC) transporter
BVG89_01830	COG0347	Belongs to the P(II) protein family
BVG89_01835	COG0004	ammonium transporteR
BVG89_01840	COG1946	Acyl-CoA thioesterase
BVG89_01845	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BVG89_01850	COG3695	enzyme binding
BVG89_01880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BVG89_01885	COG0803	Belongs to the bacterial solute-binding protein 9 family
BVG89_01890	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BVG89_01895	COG0254	rRNA binding
BVG89_01900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVG89_01905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVG89_01910	COG1309	transcriptional regulator
BVG89_01915	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BVG89_01920	COG3264	Mechanosensitive ion channel
BVG89_01920	COG1196	nuclear chromosome segregation
BVG89_01935	COG2832	Protein of unknown function (DUF454)
BVG89_01940	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BVG89_01945	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BVG89_01955	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BVG89_01960	COG0326	Molecular chaperone. Has ATPase activity
BVG89_01965	COG0563	adenylate kinase activity
BVG89_01970	COG3835	regulator
BVG89_01975	COG2610	gluconate transmembrane transporter activity
BVG89_01980	COG1929	Belongs to the glycerate kinase type-1 family
BVG89_01985	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BVG89_01990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVG89_01995	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BVG89_01995	COG4651	solute:proton antiporter activity
BVG89_02000	COG2223	nitrite transmembrane transporter activity
BVG89_02005	COG0737	Belongs to the 5'-nucleotidase family
BVG89_02015	COG2814	Major facilitator Superfamily
BVG89_02020	COG2027	D-alanyl-D-alanine carboxypeptidase
BVG89_02025	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BVG89_02030	COG3735	TraB family
BVG89_02035	COG2217	Heavy metal translocating P-type atpase
BVG89_02040	COG0789	Transcriptional regulator
BVG89_02045	COG1585	Membrane protein implicated in regulation of membrane protease activity
BVG89_02050	COG0330	HflC and HflK could
BVG89_02055	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BVG89_02060	COG3118	belongs to the thioredoxin family
BVG89_02065	COG0300	oxidoreductase activity
BVG89_02070	COG2755	lipolytic protein G-D-S-L family
BVG89_02075	COG4181	ATPase activity
BVG89_02080	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BVG89_02085	COG2814	Major facilitator Superfamily
BVG89_02090	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BVG89_02095	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BVG89_02100	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVG89_02105	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BVG89_02110	COG0215	cysteine-tRNA ligase activity
BVG89_02115	COG2501	S4 domain
BVG89_02120	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BVG89_02155	COG2199	diguanylate cyclase activity
BVG89_02160	COG1278	Cold shock
BVG89_02175	COG0765	amino acid transport
BVG89_02190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVG89_02200	COG1278	Cold shock
BVG89_02205	COG2814	Major facilitator Superfamily
BVG89_02215	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BVG89_02225	COG3706	GGDEF domain
BVG89_02235	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BVG89_02240	COG0321	lipoyl(octanoyl) transferase activity
BVG89_02250	COG1686	Belongs to the peptidase S11 family
BVG89_02255	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BVG89_02260	COG0772	Belongs to the SEDS family
BVG89_02265	COG0768	penicillin binding
BVG89_02270	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BVG89_02275	COG0799	negative regulation of ribosome biogenesis
BVG89_02280	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BVG89_02285	COG1466	dna polymerase III delta subunit
BVG89_02290	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BVG89_02295	COG0495	leucyl-tRNA aminoacylation
BVG89_02300	COG2888	peptidyl-tyrosine sulfation
BVG89_02310	COG1957	nucleoside hydrolase
BVG89_02315	COG1126	abc transporter atp-binding protein
BVG89_02320	COG0765	amino acid transport
BVG89_02325	COG0765	amino acid transport
BVG89_02335	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BVG89_02340	COG4535	Mg2 and Co2 transporter CorC
BVG89_02345	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BVG89_02350	COG1702	phosphate starvation-inducible protein PhoH
BVG89_02355	COG2824	Alkylphosphonate utilization operon protein PhnA
BVG89_02360	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BVG89_02365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVG89_02400	COG0367	asparagine synthase
BVG89_02405	COG3469	chitinase activity
BVG89_02410	COG0647	UMP catabolic process
BVG89_02415	COG1940	carbohydrate kinase activity
BVG89_02415	COG1846	Transcriptional regulator
BVG89_02420	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BVG89_02425	COG0363	glucosamine-6-phosphate deaminase activity
BVG89_02430	COG1263	PTS System
BVG89_02430	COG2190	(PTS) system
BVG89_02430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVG89_02435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BVG89_02455	COG0735	belongs to the Fur family
BVG89_02470	COG0596	Alpha beta hydrolase
BVG89_02475	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BVG89_02480	COG0033	Phosphoglucomutase
BVG89_02485	COG1695	Transcriptional regulator
BVG89_02495	COG0745	RESPONSE REGULATOR receiver
BVG89_02500	COG2205	protein histidine kinase activity
BVG89_02505	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BVG89_02510	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BVG89_02515	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BVG89_02530	COG3272	Protein of unknown function (DUF1722)
BVG89_02535	COG0415	Belongs to the DNA photolyase family
BVG89_02540	COG5212	phosphodiesterase
BVG89_02545	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BVG89_02550	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BVG89_02555	COG1984	allophanate hydrolase subunit 2
BVG89_02560	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BVG89_02590	COG2009	succinate dehydrogenase
BVG89_02595	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BVG89_02600	COG1053	succinate dehydrogenase
BVG89_02605	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BVG89_02610	COG0567	Dehydrogenase, E1 component
BVG89_02615	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVG89_02620	COG0045	succinate-CoA ligase (ADP-forming) activity
BVG89_02625	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BVG89_02630	COG0737	Belongs to the 5'-nucleotidase family
BVG89_02635	COG1271	oxidase subunit
BVG89_02640	COG1294	oxidase, subunit
BVG89_02645	COG4890	Cyd operon protein YbgT
BVG89_02650	COG3790	cyd operon protein YbgE
BVG89_02655	COG0824	Thioesterase
BVG89_02660	COG0811	peptide transport
BVG89_02665	COG0848	biopolymer transport protein
BVG89_02670	COG3064	Membrane
BVG89_02675	COG0823	Involved in the tonB-independent uptake of proteins
BVG89_02680	COG2885	chlorophyll binding
BVG89_02685	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BVG89_02730	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BVG89_02740	COG1230	cation diffusion facilitator family transporter
BVG89_02745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVG89_02745	COG2205	protein histidine kinase activity
BVG89_02750	COG2197	response regulator
BVG89_02755	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BVG89_02770	COG0588	phosphoglycerate mutase activity
BVG89_02780	COG2017	converts alpha-aldose to the beta-anomer
BVG89_02785	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BVG89_02805	COG1119	ATPase activity
BVG89_02810	COG3585	molybdate ion transport
BVG89_02810	COG2005	Transcriptional regulator
BVG89_02815	COG4774	siderophore transport
BVG89_02825	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BVG89_02830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVG89_02835	COG1120	ATPase activity
BVG89_02845	COG0725	ABC transporter, periplasmic molybdate-binding protein
BVG89_02850	COG4149	molybdate abc transporter
BVG89_02860	COG0561	phosphatase activity
BVG89_02865	COG2706	6-phosphogluconolactonase activity
BVG89_02870	COG1881	PFAM PEBP family protein
BVG89_02930	COG0556	nucleotide-excision repair
BVG89_02935	COG4628	conserved protein (DUF2132)
BVG89_02940	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BVG89_02945	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BVG89_02950	COG0521	Mo-molybdopterin cofactor biosynthetic process
BVG89_02955	COG0315	cyclic pyranopterin monophosphate synthase activity
BVG89_02960	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BVG89_02965	COG0314	molybdopterin synthase activity
BVG89_02970	COG0670	Belongs to the BI1 family
BVG89_02975	COG3209	COG3209 Rhs family protein
BVG89_03025	COG0842	Transport permease protein
BVG89_03030	COG0842	Transport permease protein
BVG89_03035	COG1131	(ABC) transporter
BVG89_03040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVG89_03045	COG1309	transcriptional regulator
BVG89_03050	COG0513	Belongs to the DEAD box helicase family
BVG89_03055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BVG89_03060	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BVG89_03070	COG3842	ATPase activity
BVG89_03080	COG1840	ABC-type Fe3 transport system, periplasmic component
BVG89_03085	COG2271	Major facilitator Superfamily
BVG89_03110	COG0679	Auxin Efflux Carrier
BVG89_03120	COG0469	pyruvate kinase activity
BVG89_03125	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_03135	COG0583	DNA-binding transcription factor activity
BVG89_03155	COG0583	DNA-binding transcription factor activity
BVG89_03160	COG0586	Pfam SNARE associated Golgi protein
BVG89_03170	COG4977	sequence-specific DNA binding
BVG89_03175	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BVG89_03180	COG1686	Belongs to the peptidase S11 family
BVG89_03210	COG2354	Protein conserved in bacteria
BVG89_03225	COG3692	DNA binding
BVG89_03230	COG1464	Belongs to the NlpA lipoprotein family
BVG89_03240	COG0456	acetyltransferase
BVG89_03260	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BVG89_03270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVG89_03280	COG0840	transmembrane signaling receptor activity
BVG89_03285	COG0277	FAD linked oxidase domain protein
BVG89_03290	COG0024	Methionine aminopeptidase
BVG89_03300	COG1181	Belongs to the D-alanine--D-alanine ligase family
BVG89_03310	COG0436	Aminotransferase
BVG89_03320	COG1472	Belongs to the glycosyl hydrolase 3 family
BVG89_03360	COG0596	Alpha beta hydrolase
BVG89_03370	COG1846	Transcriptional regulator
BVG89_03395	COG1192	Involved in chromosome partitioning
BVG89_03400	COG1403	HNH endonuclease
BVG89_03405	COG0583	DNA-binding transcription factor activity
BVG89_03415	COG1070	Carbohydrate kinase
BVG89_03420	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BVG89_03425	COG0697	spore germination
BVG89_03435	COG2207	Transcriptional regulator
BVG89_03480	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BVG89_03495	COG1309	transcriptional regulator
BVG89_03500	COG1464	Belongs to the NlpA lipoprotein family
BVG89_03505	COG2011	ABC-type metal ion transport system permease component
BVG89_03510	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BVG89_03515	COG0519	Catalyzes the synthesis of GMP from XMP
BVG89_03530	COG1335	isochorismatase
BVG89_03535	COG2084	Dehydrogenase
BVG89_03550	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BVG89_03565	COG4807	Protein conserved in bacteria
BVG89_03585	COG1802	Transcriptional regulator
BVG89_03595	COG0559	Belongs to the binding-protein-dependent transport system permease family
BVG89_03605	COG0411	ABC transporter
BVG89_03675	COG0583	DNA-binding transcription factor activity
BVG89_03680	COG2897	thiosulfate sulfurtransferase activity
BVG89_03700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVG89_03710	COG0625	glutathione transferase activity
BVG89_03720	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BVG89_03730	COG1335	isochorismatase
BVG89_03735	COG0583	DNA-binding transcription factor activity
BVG89_03755	COG1732	Glycine betaine
BVG89_03760	COG1174	glycine betaine transport
BVG89_03765	COG1125	glycine betaine transport
BVG89_03770	COG1174	glycine betaine transport
BVG89_03785	COG0583	DNA-binding transcription factor activity
BVG89_03790	COG0697	spore germination
BVG89_03835	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BVG89_03850	COG0625	glutathione transferase activity
BVG89_03860	COG1942	4-Oxalocrotonate Tautomerase
BVG89_03870	COG1522	sequence-specific DNA binding
BVG89_03875	COG0697	spore germination
BVG89_03895	COG2079	MmgE PrpD family protein
BVG89_03900	COG1280	lysine exporter protein (LysE YggA)
BVG89_03910	COG0477	Major facilitator Superfamily
BVG89_03920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BVG89_03940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVG89_03945	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BVG89_03955	COG1309	transcriptional regulator
BVG89_03960	COG0456	acetyltransferase
BVG89_03960	COG1214	PFAM Peptidase M22, glycoprotease
BVG89_03970	COG0668	transmembrane transport
BVG89_03975	COG1126	abc transporter atp-binding protein
BVG89_03980	COG0765	amino acid transport
BVG89_03985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVG89_03990	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BVG89_04005	COG2731	YhcH YjgK YiaL family protein
BVG89_04015	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BVG89_04020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVG89_04035	COG2610	gluconate transmembrane transporter activity
BVG89_04040	COG3622	Belongs to the hyi family
BVG89_04045	COG0235	Class ii aldolase
BVG89_04050	COG3395	kinase activity
BVG89_04055	COG2084	Dehydrogenase
BVG89_04060	COG1349	DNA-binding transcription factor activity
BVG89_04070	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BVG89_04075	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
BVG89_04095	COG5002	protein histidine kinase activity
BVG89_04100	COG0745	RESPONSE REGULATOR receiver
BVG89_04105	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
BVG89_04110	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BVG89_04125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BVG89_04130	COG1309	transcriptional regulator
BVG89_04135	COG1012	belongs to the aldehyde dehydrogenase family
BVG89_04140	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BVG89_04145	COG0069	glutamate synthase activity
BVG89_04155	COG2200	EAL domain
BVG89_04165	COG3121	Chaperone
BVG89_04170	COG3188	usher protein
BVG89_04180	COG3708	Transcriptional regulator
BVG89_04180	COG2207	Transcriptional regulator
BVG89_04185	COG0579	oxidoreductase
BVG89_04195	COG0625	glutathione transferase activity
BVG89_04200	COG0640	Transcriptional regulator
BVG89_04210	COG1335	isochorismatase
BVG89_04215	COG0583	DNA-binding transcription factor activity
BVG89_04230	COG3811	Belongs to the UPF0386 family
BVG89_04235	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
BVG89_04245	COG0583	DNA-binding transcription factor activity
BVG89_04270	COG0488	(ABC) transporter
BVG89_04275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BVG89_04280	COG0303	'Molybdopterin
BVG89_04295	COG4172	Belongs to the ABC transporter superfamily
BVG89_04300	COG0747	negative chemotaxis
BVG89_04305	COG0601	transmembrane transport
BVG89_04310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BVG89_04335	COG0583	DNA-binding transcription factor activity
BVG89_04340	COG0477	Major facilitator Superfamily
BVG89_04345	COG0302	gtp cyclohydrolase
BVG89_04350	COG2311	Membrane
BVG89_04355	COG1609	Transcriptional regulator
BVG89_04380	COG2949	membrane
BVG89_04385	COG0281	malic enzyme
BVG89_04390	COG0295	cytidine deaminase activity
BVG89_04395	COG1346	cytolysis
BVG89_04400	COG1380	Effector of murein hydrolase LrgA
BVG89_04405	COG2814	Major facilitator Superfamily
BVG89_04415	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVG89_04415	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVG89_04420	COG0489	protein tyrosine kinase activity
BVG89_04430	COG0572	uridine kinase
BVG89_04435	COG0717	Belongs to the dCTP deaminase family
BVG89_04440	COG2982	Protein involved in outer membrane biogenesis
BVG89_04445	COG3069	C4-dicarboxylate transmembrane transporter activity
BVG89_04450	COG1253	flavin adenine dinucleotide binding
BVG89_04455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BVG89_04460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BVG89_04495	COG2244	polysaccharide biosynthetic process
BVG89_04500	COG5039	Polysaccharide pyruvyl transferase
BVG89_04505	COG1442	glycosyl transferase family 8
BVG89_04505	COG1216	Glycosyl transferase, family 2
BVG89_04515	COG0297	glycogen (starch) synthase activity
BVG89_04520	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BVG89_04555	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BVG89_04585	COG1091	dTDP-4-dehydrorhamnose reductase activity
BVG89_04625	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BVG89_04630	COG0140	phosphoribosyl-ATP diphosphatase activity
BVG89_04630	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BVG89_04635	COG0107	imidazoleglycerol-phosphate synthase activity
BVG89_04640	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BVG89_04645	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BVG89_04650	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BVG89_04650	COG0131	Imidazoleglycerol-phosphate dehydratase
BVG89_04655	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BVG89_04660	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BVG89_04665	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BVG89_04670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVG89_04675	COG0583	DNA-binding transcription factor activity
BVG89_04680	COG2814	Major facilitator Superfamily
BVG89_04695	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BVG89_04700	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BVG89_04705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVG89_04705	COG3153	acetyltransferase
BVG89_04710	COG0598	Magnesium transport protein CorA
BVG89_04720	COG2133	pyrroloquinoline quinone binding
BVG89_04725	COG0625	glutathione transferase activity
BVG89_04740	COG0626	cystathionine gamma-synthase activity
BVG89_04750	COG1686	Belongs to the peptidase S11 family
BVG89_04780	COG3188	usher protein
BVG89_04785	COG3121	Chaperone
BVG89_04810	COG2197	response regulator
BVG89_04815	COG1760	l-serine dehydratase
BVG89_04820	COG0814	amino acid
BVG89_04825	COG1349	DNA-binding transcription factor activity
BVG89_04830	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BVG89_04840	COG0671	phosphoesterase, PA-phosphatase related
BVG89_04850	COG4574	serine-type endopeptidase inhibitor activity
BVG89_04870	COG1595	DNA-templated transcription, initiation
BVG89_04875	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BVG89_04885	COG0569	domain protein
BVG89_04885	COG2985	domain, Protein
BVG89_04895	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BVG89_04905	COG0189	ligase activity
BVG89_04915	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BVG89_04920	COG3842	ATPase activity
BVG89_04925	COG1176	ABC-type spermidine putrescine transport system, permease component I
BVG89_04930	COG1177	transmembrane transport
BVG89_04940	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BVG89_04945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVG89_04950	COG4160	amino acid transport
BVG89_04955	COG4215	(ABC) transporter
BVG89_04960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVG89_04965	COG1126	abc transporter atp-binding protein
BVG89_04975	COG0393	Putative heavy-metal-binding
BVG89_04985	COG3023	N-Acetylmuramoyl-L-alanine amidase
BVG89_04990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVG89_04995	COG0702	epimerase
BVG89_05005	COG1737	Transcriptional regulator
BVG89_05010	COG2190	(PTS) system
BVG89_05010	COG1263	PTS System
BVG89_05010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVG89_05015	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BVG89_05020	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BVG89_05025	COG0028	Belongs to the TPP enzyme family
BVG89_05030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BVG89_05035	COG1151	hydroxylamine reductase activity
BVG89_05040	COG2431	L-lysine efflux transmembrane transporter activity
BVG89_05045	COG3593	DNA synthesis involved in DNA repair
BVG89_05050	COG2990	Protein conserved in bacteria
BVG89_05055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVG89_05065	COG1278	Cold shock
BVG89_05070	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BVG89_05075	COG0542	response to heat
BVG89_05080	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BVG89_05085	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BVG89_05090	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BVG89_05105	COG0583	DNA-binding transcription factor activity
BVG89_05110	COG0492	ferredoxin-NADP+ reductase activity
BVG89_05120	COG1674	ftsk spoiiie
BVG89_05120	COG3107	peptidoglycan biosynthetic process
BVG89_05125	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BVG89_05130	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BVG89_05135	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BVG89_05145	COG2814	Major facilitator Superfamily
BVG89_05150	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BVG89_05155	COG1882	Formate acetyltransferase
BVG89_05160	COG2116	formate transmembrane transporter activity
BVG89_05165	COG1944	ATP diphosphatase activity
BVG89_05170	COG0252	asparaginase activity
BVG89_05175	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BVG89_05180	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BVG89_05185	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BVG89_05190	COG0539	negative regulation of cytoplasmic translation
BVG89_05200	COG2333	competence protein COMEC
BVG89_05200	COG0658	competence protein
BVG89_05205	COG1132	(ABC) transporter
BVG89_05210	COG1663	tetraacyldisaccharide 4'-kinase activity
BVG89_05215	COG5383	Protein conserved in bacteria
BVG89_05220	COG1278	Cold shock
BVG89_05225	COG1278	Cold shock
BVG89_05230	COG3214	Protein conserved in bacteria
BVG89_05235	COG2835	tetraacyldisaccharide 4'-kinase activity
BVG89_05240	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BVG89_05245	COG3173	Aminoglycoside phosphotransferase
BVG89_05250	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BVG89_05255	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BVG89_05260	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
BVG89_05265	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BVG89_05270	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BVG89_05275	COG2989	Protein conserved in bacteria
BVG89_05280	COG3108	Peptidase M15
BVG89_05285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVG89_05290	COG1448	Aminotransferase
BVG89_05300	COG0017	Asparaginyl-tRNA synthetase
BVG89_05305	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BVG89_05310	COG3706	GGDEF domain
BVG89_05315	COG0308	aminopeptidase N
BVG89_05325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVG89_05330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVG89_05335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVG89_05340	COG0431	NADPH-dependent FMN reductase
BVG89_05345	COG0167	dihydroorotate dehydrogenase activity
BVG89_05355	COG0633	Ferredoxin
BVG89_05355	COG3217	Mosc domain protein beta barrel domain protein
BVG89_05360	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BVG89_05360	COG0116	Belongs to the methyltransferase superfamily
BVG89_05365	COG0488	(ABC) transporter
BVG89_05370	COG2995	paraquat-inducible protein a
BVG89_05375	COG3008	intermembrane lipid transfer
BVG89_05375	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BVG89_05380	COG3009	Protein conserved in bacteria
BVG89_05390	COG3130	regulation of translation
BVG89_05395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BVG89_05405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BVG89_05410	COG1067	ATP-dependent peptidase activity
BVG89_05430	COG3070	regulator of competence-specific genes
BVG89_05435	COG1289	transmembrane transporter activity
BVG89_05440	COG3304	Inner membrane component domain
BVG89_05445	COG0210	DNA helicase
BVG89_05450	COG1803	Methylglyoxal synthase
BVG89_05460	COG1832	CoA-binding protein
BVG89_05465	COG3785	DNA binding
BVG89_05470	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BVG89_05475	COG1254	Belongs to the acylphosphatase family
BVG89_05480	COG2920	part of a sulfur-relay system
BVG89_05485	COG0670	Belongs to the BI1 family
BVG89_05505	COG3121	Chaperone
BVG89_05510	COG3188	usher protein
BVG89_05530	COG0789	Transcriptional regulator
BVG89_05535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVG89_05540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVG89_05555	COG0655	NAD(P)H dehydrogenase (quinone) activity
BVG89_05585	COG1113	amino acid transport
BVG89_05600	COG2271	Major facilitator Superfamily
BVG89_05625	COG2814	Major facilitator Superfamily
BVG89_05630	COG0156	8-amino-7-oxononanoate synthase activity
BVG89_05635	COG0183	Belongs to the thiolase family
BVG89_05640	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVG89_05645	COG2197	response regulator
BVG89_05650	COG0589	response to stress
BVG89_05665	COG0531	amino acid
BVG89_05670	COG1012	belongs to the aldehyde dehydrogenase family
BVG89_05675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVG89_05690	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BVG89_05690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVG89_05715	COG3136	membrane protein required for alginate biosynthesis
BVG89_05725	COG2197	response regulator
BVG89_05730	COG0322	excinuclease ABC activity
BVG89_05750	COG4221	oxidoreductase activity
BVG89_05765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVG89_05780	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BVG89_05815	COG0583	DNA-binding transcription factor activity
BVG89_05825	COG1538	Outer membrane efflux protein
BVG89_05835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVG89_05840	COG0322	excinuclease ABC activity
BVG89_05875	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BVG89_05880	COG2943	transferase activity, transferring hexosyl groups
BVG89_05885	COG5645	(Lipo)protein
BVG89_05900	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BVG89_05910	COG0640	Transcriptional regulator
BVG89_05925	COG0346	lactoylglutathione lyase activity
BVG89_05930	COG3104	oligopeptide transport
BVG89_05935	COG2814	Major facilitator Superfamily
BVG89_05945	COG1560	Kdo2-lipid A biosynthetic process
BVG89_05960	COG2353	YceI-like domain
BVG89_05965	COG3038	cytochrome b561
BVG89_05970	COG0628	permease
BVG89_06010	COG0418	dihydroorotase activity
BVG89_06015	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BVG89_06020	COG1530	ribonuclease E activity
BVG89_06025	COG0564	pseudouridine synthase activity
BVG89_06035	COG1399	metal-binding, possibly nucleic acid-binding protein
BVG89_06040	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BVG89_06045	COG0416	fatty acid biosynthetic process
BVG89_06050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BVG89_06055	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BVG89_06060	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_06065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVG89_06070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BVG89_06075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BVG89_06080	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BVG89_06085	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BVG89_06090	COG0470	DNA polymerase III
BVG89_06095	COG0084	hydrolase, TatD family'
BVG89_06100	COG1263	PTS System
BVG89_06100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVG89_06110	COG1321	iron dependent repressor
BVG89_06115	COG1914	H( )-stimulated, divalent metal cation uptake system
BVG89_06130	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_06135	COG1733	regulation of RNA biosynthetic process
BVG89_06140	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BVG89_06145	COG0537	adenosine 5'-monophosphoramidase activity
BVG89_06150	COG5633	Lipoprotein
BVG89_06155	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
BVG89_06160	COG0510	thiamine kinase activity
BVG89_06170	COG3150	esterase
BVG89_06175	COG1252	NADH dehydrogenase
BVG89_06180	COG3134	Outer membrane lipoprotein
BVG89_06195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVG89_06200	COG3708	Transcriptional regulator
BVG89_06200	COG2207	Transcriptional regulator
BVG89_06240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BVG89_06245	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BVG89_06250	COG3381	protein complex oligomerization
BVG89_06255	COG2979	Protein of unknown function (DUF533)
BVG89_06260	COG1770	oligopeptidase
BVG89_06265	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BVG89_06270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVG89_06275	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BVG89_06280	COG0583	DNA-binding transcription factor activity
BVG89_06300	COG1528	Iron-storage protein
BVG89_06305	COG2372	response to copper ion
BVG89_06310	COG1276	copper resistance
BVG89_06340	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BVG89_06350	COG3655	Transcriptional regulator
BVG89_06375	COG4565	transcriptional regulatory protein
BVG89_06380	COG3290	protein histidine kinase activity
BVG89_06395	COG1129	ABC transporter
BVG89_06400	COG1172	Belongs to the binding-protein-dependent transport system permease family
BVG89_06415	COG1464	Belongs to the NlpA lipoprotein family
BVG89_06425	COG0589	response to stress
BVG89_06430	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BVG89_06430	COG3408	Glycogen debranching enzyme
BVG89_06440	COG1609	Transcriptional regulator
BVG89_06445	COG3250	beta-galactosidase activity
BVG89_06450	COG2731	YhcH YjgK YiaL family protein
BVG89_06455	COG0531	amino acid
BVG89_06460	COG0640	Transcriptional regulator
BVG89_06470	COG0740	serine-type endopeptidase activity
BVG89_06500	COG3121	Chaperone
BVG89_06540	COG0012	GTP binding
BVG89_06545	COG0659	secondary active sulfate transmembrane transporter activity
BVG89_06550	COG0193	aminoacyl-tRNA hydrolase activity
BVG89_06560	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BVG89_06565	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BVG89_06570	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BVG89_06575	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BVG89_06580	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BVG89_06585	COG2890	protein-(glutamine-N5) methyltransferase activity
BVG89_06590	COG3094	Invasion gene expression up-regulator, SirB
BVG89_06595	COG2912	Transglutaminase-like superfamily
BVG89_06600	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BVG89_06605	COG0659	secondary active sulfate transmembrane transporter activity
BVG89_06610	COG4702	Belongs to the UPF0303 family
BVG89_06615	COG3706	GGDEF domain
BVG89_06620	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BVG89_06630	COG4591	ABC-type transport system involved in lipoprotein release permease component
BVG89_06640	COG4591	ABC-type transport system involved in lipoprotein release permease component
BVG89_06650	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BVG89_06655	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BVG89_06665	COG1486	melibiose metabolic process
BVG89_06670	COG1263	PTS System
BVG89_06670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVG89_06675	COG1177	transmembrane transport
BVG89_06680	COG1176	ABC-type spermidine putrescine transport system, permease component I
BVG89_06690	COG2195	Cleaves the N-terminal amino acid of tripeptides
BVG89_06695	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BVG89_06700	COG2850	peptidyl-arginine hydroxylation
BVG89_06710	COG0745	RESPONSE REGULATOR receiver
BVG89_06715	COG1397	ADP-ribosylglycohydrolase
BVG89_06720	COG2188	Transcriptional regulator
BVG89_06750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVG89_06755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BVG89_06760	COG2915	High frequency lysogenization protein hflD homolog
BVG89_06770	COG0482	sulfurtransferase activity
BVG89_06785	COG1187	pseudouridine synthase activity
BVG89_06790	COG0538	isocitrate dehydrogenase activity
BVG89_06800	COG0589	response to stress
BVG89_06815	COG3064	Membrane
BVG89_06860	COG1609	Transcriptional regulator
BVG89_06870	COG0673	inositol 2-dehydrogenase activity
BVG89_06900	COG1278	Cold shock
BVG89_06910	COG1335	isochorismatase
BVG89_06915	COG0589	response to stress
BVG89_06920	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_06925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVG89_06930	COG1012	belongs to the aldehyde dehydrogenase family
BVG89_06935	COG1396	sequence-specific DNA binding
BVG89_06935	COG1917	Cupin 2, conserved barrel domain protein
BVG89_06940	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BVG89_06945	COG0174	glutamine synthetase
BVG89_06955	COG0531	amino acid
BVG89_06970	COG4977	sequence-specific DNA binding
BVG89_06995	COG1605	Chorismate mutase
BVG89_07010	COG1228	amidohydrolase
BVG89_07020	COG0402	S-adenosylhomocysteine deaminase activity
BVG89_07040	COG2211	Major facilitator Superfamily
BVG89_07045	COG0477	Major facilitator Superfamily
BVG89_07065	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BVG89_07070	COG3493	citrate carrier protein
BVG89_07135	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BVG89_07135	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BVG89_07140	COG3008	intermembrane lipid transfer
BVG89_07145	COG2995	paraquat-inducible protein a
BVG89_07150	COG1956	GAF domain-containing protein
BVG89_07155	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
BVG89_07160	COG0793	Belongs to the peptidase S41A family
BVG89_07165	COG0501	Belongs to the peptidase M48B family
BVG89_07175	COG2814	Major facilitator Superfamily
BVG89_07205	COG2188	Transcriptional regulator
BVG89_07225	COG1988	membrane-bound metal-dependent
BVG89_07230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BVG89_07250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BVG89_07255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BVG89_07260	COG1121	(ABC) transporter
BVG89_07265	COG0803	Belongs to the bacterial solute-binding protein 9 family
BVG89_07295	COG0814	amino acid
BVG89_07325	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BVG89_07335	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BVG89_07340	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BVG89_07345	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BVG89_07365	COG4139	cobalamin transport
BVG89_07370	COG0386	Belongs to the glutathione peroxidase family
BVG89_07375	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
BVG89_07380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BVG89_07385	COG1215	transferase activity, transferring glycosyl groups
BVG89_07390	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BVG89_07390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVG89_07395	COG0726	polysaccharide deacetylase
BVG89_07400	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BVG89_07405	COG2076	Multidrug Resistance protein
BVG89_07410	COG2076	Multidrug Resistance protein
BVG89_07415	COG0791	NLP P60 protein
BVG89_07420	COG0095	Lipoate-protein ligase
BVG89_07440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVG89_07445	COG4558	Periplasmic binding protein
BVG89_07450	COG3720	iron ion transport
BVG89_07465	COG0386	Belongs to the glutathione peroxidase family
BVG89_07470	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BVG89_07475	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BVG89_07485	COG0574	Belongs to the PEP-utilizing enzyme family
BVG89_07485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BVG89_07495	COG0628	permease
BVG89_07500	COG0247	lactate metabolic process
BVG89_07500	COG0277	FAD linked oxidase domain protein
BVG89_07505	COG2050	protein possibly involved in aromatic compounds catabolism
BVG89_07515	COG0316	Belongs to the HesB IscA family
BVG89_07520	COG0719	Fe-S assembly protein
BVG89_07525	COG0396	ATPase activity
BVG89_07530	COG0719	Fe-S assembly protein
BVG89_07535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BVG89_07540	COG2166	iron-sulfur cluster assembly
BVG89_07545	COG1376	ErfK ybiS ycfS ynhG family protein
BVG89_07545	COG1388	LysM domain
BVG89_07555	COG0469	pyruvate kinase activity
BVG89_07580	COG0534	Mate efflux family protein
BVG89_07585	COG0307	riboflavin synthase, alpha
BVG89_07595	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BVG89_07600	COG2814	Major facilitator Superfamily
BVG89_07605	COG0583	DNA-binding transcription factor activity
BVG89_07610	COG1609	Transcriptional regulator
BVG89_07615	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BVG89_07620	COG0791	NLP P60 protein
BVG89_07625	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BVG89_07630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BVG89_07635	COG0346	lactoylglutathione lyase activity
BVG89_07640	COG1902	pentaerythritol trinitrate reductase activity
BVG89_07645	COG1309	transcriptional regulator
BVG89_07650	COG2194	sulfuric ester hydrolase activity
BVG89_07660	COG0583	DNA-binding transcription factor activity
BVG89_07665	COG3313	Fe-S protein
BVG89_07670	COG4989	oxidoreductase activity
BVG89_07675	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BVG89_07685	COG1289	transmembrane transporter activity
BVG89_07690	COG1566	PFAM secretion protein HlyD family protein
BVG89_07700	COG1846	Transcriptional regulator
BVG89_07705	COG3133	Outer membrane lipoprotein
BVG89_07710	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BVG89_07720	COG0259	pyridoxamine-phosphate oxidase activity
BVG89_07725	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BVG89_07735	COG0625	glutathione transferase activity
BVG89_07750	COG1418	mRNA catabolic process
BVG89_07785	COG3135	benzoate transporter
BVG89_07790	COG1396	sequence-specific DNA binding
BVG89_07795	COG1505	serine-type exopeptidase activity
BVG89_07800	COG3104	oligopeptide transport
BVG89_07805	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BVG89_07815	COG4659	FMN binding
BVG89_07825	COG3708	Transcriptional regulator
BVG89_07825	COG2207	Transcriptional regulator
BVG89_07830	COG4656	Part of a membrane complex involved in electron transport
BVG89_07835	COG2878	Part of a membrane complex involved in electron transport
BVG89_07840	COG4657	Part of a membrane complex involved in electron transport
BVG89_07850	COG0673	inositol 2-dehydrogenase activity
BVG89_07855	COG0385	Bile acid
BVG89_07865	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BVG89_07870	COG1349	DNA-binding transcription factor activity
BVG89_07875	COG0494	nUDIX hydrolase
BVG89_07885	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BVG89_07890	COG1263	PTS System
BVG89_07890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVG89_07895	COG1609	Transcriptional regulator
BVG89_07910	COG0583	DNA-binding transcription factor activity
BVG89_07920	COG5339	Protein conserved in bacteria
BVG89_07935	COG0114	fumarate hydratase activity
BVG89_07950	COG2378	regulation of single-species biofilm formation
BVG89_07975	COG2814	Major facilitator Superfamily
BVG89_07980	COG0583	DNA-binding transcription factor activity
BVG89_07985	COG1940	carbohydrate kinase activity
BVG89_07990	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BVG89_08000	COG0789	Transcriptional regulator
BVG89_08030	COG0477	Major facilitator Superfamily
BVG89_08045	COG1742	UPF0060 membrane protein
BVG89_08050	COG4221	oxidoreductase activity
BVG89_08060	COG4772	TonB-dependent receptor
BVG89_08065	COG3712	iron ion homeostasis
BVG89_08070	COG1595	DNA-templated transcription, initiation
BVG89_08075	COG0402	S-adenosylhomocysteine deaminase activity
BVG89_08135	COG0339	signal peptide processing
BVG89_08140	COG0583	DNA-binding transcription factor activity
BVG89_08150	COG2271	Major facilitator Superfamily
BVG89_08155	COG1335	isochorismatase
BVG89_08160	COG3473	Maleate cis-trans isomerase
BVG89_08165	COG0596	Alpha beta hydrolase
BVG89_08170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVG89_08175	COG2309	aminopeptidase activity
BVG89_08180	COG1846	Transcriptional regulator
BVG89_08185	COG2080	2 iron, 2 sulfur cluster binding
BVG89_08190	COG2010	Cytochrome c
BVG89_08190	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BVG89_08195	COG0583	DNA-binding transcription factor activity
BVG89_08235	COG2140	Oxalate decarboxylase
BVG89_08240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVG89_08240	COG2190	(PTS) system
BVG89_08240	COG1263	PTS System
BVG89_08245	COG2723	6-phospho-beta-galactosidase activity
BVG89_08250	COG3711	transcriptional antiterminator
BVG89_08290	COG0596	Alpha beta hydrolase
BVG89_08325	COG3209	COG3209 Rhs family protein
BVG89_08370	COG0384	phenazine biosynthesis protein PhzF
BVG89_08380	COG2169	Transcriptional regulator
BVG89_08380	COG1917	Cupin 2, conserved barrel domain protein
BVG89_08400	COG2814	Major facilitator Superfamily
BVG89_08420	COG0768	penicillin binding
BVG89_08435	COG0840	transmembrane signaling receptor activity
BVG89_08460	COG1126	abc transporter atp-binding protein
BVG89_08465	COG0765	amino acid transport
BVG89_08480	COG2079	MmgE PrpD family protein
BVG89_08495	COG2814	Major facilitator Superfamily
BVG89_08505	COG1349	DNA-binding transcription factor activity
BVG89_08510	COG0673	inositol 2-dehydrogenase activity
BVG89_08515	COG2814	Major facilitator Superfamily
BVG89_08540	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BVG89_08545	COG2862	Uncharacterized protein family, UPF0114
BVG89_08550	COG2814	Major facilitator Superfamily
BVG89_08555	COG0583	DNA-binding transcription factor activity
BVG89_08580	COG1064	alcohol dehydrogenase
BVG89_08585	COG1012	belongs to the aldehyde dehydrogenase family
BVG89_08590	COG3284	Transcriptional regulator
BVG89_08605	COG3300	MHYT domain
BVG89_08605	COG5001	Diguanylate cyclase
BVG89_08660	COG0583	DNA-binding transcription factor activity
BVG89_08670	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BVG89_08680	COG0076	glutamate decarboxylase activity
BVG89_08685	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BVG89_08690	COG1902	pentaerythritol trinitrate reductase activity
BVG89_08690	COG0446	pyridine nucleotide-disulphide oxidoreductase
BVG89_08695	COG0789	Transcriptional regulator
BVG89_08700	COG0148	phosphopyruvate hydratase activity
BVG89_08710	COG1227	inorganic diphosphatase activity
BVG89_08715	COG5002	protein histidine kinase activity
BVG89_08715	COG5001	Diguanylate cyclase
BVG89_08715	COG3447	MASE1 domain protein
BVG89_08730	COG0583	DNA-binding transcription factor activity
BVG89_08775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVG89_08780	COG3118	belongs to the thioredoxin family
BVG89_08790	COG0640	Transcriptional regulator
BVG89_08800	COG1063	alcohol dehydrogenase
BVG89_08805	COG1082	Xylose isomerase domain protein TIM barrel
BVG89_08810	COG0673	inositol 2-dehydrogenase activity
BVG89_08835	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BVG89_08835	COG0456	acetyltransferase
BVG89_08845	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BVG89_08875	COG2249	NAD(P)H dehydrogenase (quinone) activity
BVG89_08880	COG1280	lysine exporter protein (LysE YggA)
BVG89_08885	COG2249	NAD(P)H dehydrogenase (quinone) activity
BVG89_08890	COG1733	regulation of RNA biosynthetic process
BVG89_08895	COG0477	Major facilitator Superfamily
BVG89_08900	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BVG89_08900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVG89_08910	COG2382	esterase
BVG89_08915	COG4774	siderophore transport
BVG89_08920	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_08935	COG1113	amino acid transport
BVG89_08940	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BVG89_08950	COG0693	protein deglycase activity
BVG89_08975	COG0789	Transcriptional regulator
BVG89_08995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVG89_09015	COG2957	Belongs to the agmatine deiminase family
BVG89_09030	COG0243	molybdopterin cofactor binding
BVG89_09050	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BVG89_09055	COG3192	ethanolamine utilization protein
BVG89_09080	COG0778	Nitroreductase
BVG89_09085	COG2010	Cytochrome c
BVG89_09085	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BVG89_09090	COG2010	Cytochrome c
BVG89_09090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BVG89_09095	COG2080	2 iron, 2 sulfur cluster binding
BVG89_09110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVG89_09115	COG1737	Transcriptional regulator
BVG89_09120	COG2723	6-phospho-beta-galactosidase activity
BVG89_09125	COG3048	D-serine ammonia-lyase activity
BVG89_09140	COG5507	3-demethylubiquinone-9 3-methyltransferase
BVG89_09145	COG2199	diguanylate cyclase activity
BVG89_09165	COG3264	Mechanosensitive ion channel
BVG89_09165	COG1196	nuclear chromosome segregation
BVG89_09170	COG0488	(ABC) transporter
BVG89_09180	COG0483	inositol monophosphate 1-phosphatase activity
BVG89_09185	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BVG89_09195	COG2239	Acts as a magnesium transporter
BVG89_09230	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BVG89_09235	COG0697	spore germination
BVG89_09290	COG0411	ABC transporter
BVG89_09330	COG0306	phosphate transporter
BVG89_09350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVG89_09370	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BVG89_09375	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BVG89_09410	COG0395	ABC-type sugar transport system, permease component
BVG89_09415	COG3842	ATPase activity
BVG89_09420	COG0673	inositol 2-dehydrogenase activity
BVG89_09425	COG1940	carbohydrate kinase activity
BVG89_09430	COG1349	DNA-binding transcription factor activity
BVG89_09435	COG2222	sugar isomerase
BVG89_09450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BVG89_09460	COG0589	response to stress
BVG89_09465	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BVG89_09470	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BVG89_09480	COG0531	amino acid
BVG89_09500	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_09505	COG0745	RESPONSE REGULATOR receiver
BVG89_09510	COG2205	protein histidine kinase activity
BVG89_09515	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BVG89_09520	COG2267	carboxylic ester hydrolase activity
BVG89_09530	COG3591	Belongs to the peptidase S1B family
BVG89_09535	COG1643	Atp-dependent helicase
BVG89_09540	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BVG89_09545	COG3784	Protein of unknown function (DUF1318)
BVG89_09555	COG2911	Protein conserved in bacteria
BVG89_09560	COG0583	DNA-binding transcription factor activity
BVG89_09570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BVG89_09575	COG3187	Heat shock protein
BVG89_09580	COG3042	response to heat
BVG89_09590	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVG89_09590	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BVG89_09590	COG0674	pyruvate-flavodoxin oxidoreductase activity
BVG89_09590	COG1013	pyruvate-flavodoxin oxidoreductase activity
BVG89_09600	COG0037	tRNA processing
BVG89_09630	COG4166	transmembrane transport
BVG89_09640	COG2866	Carboxypeptidase
BVG89_09645	COG4948	Mandelate Racemase Muconate Lactonizing
BVG89_09650	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BVG89_09660	COG3768	UPF0283 membrane protein
BVG89_09665	COG3106	COG3106 Predicted ATPase
BVG89_09675	COG1983	PspC domain protein
BVG89_09685	COG1842	Phage shock protein A
BVG89_09690	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BVG89_09700	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BVG89_09705	COG1469	GTP cyclohydrolase I activity
BVG89_09715	COG4168	peptide transport system, permease
BVG89_09720	COG4171	peptide transport system, permease
BVG89_09725	COG4172	Belongs to the ABC transporter superfamily
BVG89_09730	COG4172	Belongs to the ABC transporter superfamily
BVG89_09740	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BVG89_09740	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BVG89_09755	COG0243	molybdopterin cofactor binding
BVG89_09760	COG0583	DNA-binding transcription factor activity
BVG89_09770	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
BVG89_09775	COG0477	Major facilitator Superfamily
BVG89_09780	COG1473	amidohydrolase
BVG89_09785	COG1966	Carbon starvation protein
BVG89_09790	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BVG89_09795	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BVG89_09805	COG1349	DNA-binding transcription factor activity
BVG89_09815	COG0023	Translation Initiation Factor
BVG89_09835	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BVG89_09840	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BVG89_09845	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_09850	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BVG89_09855	COG1172	Belongs to the binding-protein-dependent transport system permease family
BVG89_09870	COG1879	ABC-type sugar transport system periplasmic component
BVG89_09875	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_09880	COG3958	Transketolase
BVG89_09885	COG3959	Transketolase, thiamine diphosphate binding domain
BVG89_09890	COG1349	DNA-binding transcription factor activity
BVG89_09895	COG0671	phosphoesterase, PA-phosphatase related
BVG89_09905	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BVG89_09915	COG3501	Rhs element vgr protein
BVG89_09920	COG0583	DNA-binding transcription factor activity
BVG89_09925	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BVG89_09935	COG0616	signal peptide processing
BVG89_09940	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_09945	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BVG89_09950	COG1187	pseudouridine synthase activity
BVG89_09965	COG0009	L-threonylcarbamoyladenylate synthase
BVG89_09970	COG0613	PHP domain protein
BVG89_09985	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BVG89_09990	COG0134	indole-3-glycerol-phosphate synthase activity
BVG89_09990	COG0135	phosphoribosylanthranilate isomerase activity
BVG89_09995	COG0133	tryptophan synthase activity
BVG89_10000	COG0159	tryptophan synthase activity
BVG89_10030	COG2917	probably involved in intracellular septation
BVG89_10035	COG1607	acyl-coa hydrolase
BVG89_10050	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BVG89_10055	COG2350	Protein conserved in bacteria
BVG89_10060	COG0583	DNA-binding transcription factor activity
BVG89_10070	COG1609	Transcriptional regulator
BVG89_10085	COG1070	Carbohydrate kinase
BVG89_10090	COG1129	ABC transporter
BVG89_10095	COG1172	Belongs to the binding-protein-dependent transport system permease family
BVG89_10100	COG1879	ABC-type sugar transport system periplasmic component
BVG89_10115	COG0783	Belongs to the Dps family
BVG89_10125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVG89_10130	COG3099	Belongs to the UPF0263 family
BVG89_10140	COG0444	Belongs to the ABC transporter superfamily
BVG89_10145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BVG89_10160	COG4166	transmembrane transport
BVG89_10165	COG2095	MarC family integral membrane protein
BVG89_10170	COG1012	belongs to the aldehyde dehydrogenase family
BVG89_10170	COG1454	alcohol dehydrogenase
BVG89_10175	COG1435	thymidine kinase activity
BVG89_10195	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BVG89_10200	COG0745	RESPONSE REGULATOR receiver
BVG89_10205	COG1752	Esterase of the alpha-beta hydrolase superfamily
BVG89_10210	COG3012	SEC-C Motif Domain Protein
BVG89_10215	COG0788	formyltetrahydrofolate deformylase activity
BVG89_10240	COG0708	Exodeoxyribonuclease III
BVG89_10245	COG0494	nUDIX hydrolase
BVG89_10255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BVG89_10260	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BVG89_10270	COG0778	Nitroreductase
BVG89_10275	COG0616	signal peptide processing
BVG89_10280	COG0252	asparaginase activity
BVG89_10285	COG1335	isochorismatase
BVG89_10295	COG3139	Protein of unknown function (DUF1315)
BVG89_10300	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BVG89_10310	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BVG89_10320	COG3713	MltA-interacting MipA family protein
BVG89_10330	COG2766	serine protein kinase
BVG89_10335	COG2718	Belongs to the UPF0229 family
BVG89_10380	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BVG89_10385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVG89_10395	COG3443	Belongs to the bacterial solute-binding protein 9 family
BVG89_10400	COG2719	SpoVR family
BVG89_10405	COG2186	Transcriptional regulator
BVG89_10410	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BVG89_10415	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BVG89_10425	COG2983	Belongs to the UPF0260 family
BVG89_10430	COG0179	Fumarylacetoacetate (FAA) hydrolase
BVG89_10435	COG2951	lytic endotransglycosylase activity
BVG89_10440	COG3100	YcgL domain-containing protein
BVG89_10445	COG0850	regulation of cytokinetic process
BVG89_10450	COG2894	cell division
BVG89_10455	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BVG89_10460	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BVG89_10465	COG0318	PFAM AMP-dependent synthetase and ligase
BVG89_10470	COG3065	identical protein binding
BVG89_10480	COG1199	ATP-dependent helicase activity
BVG89_10485	COG0251	oxidation-reduction process
BVG89_10490	COG2076	Multidrug Resistance protein
BVG89_10495	COG2076	Multidrug Resistance protein
BVG89_10500	COG0800	Aldolase
BVG89_10505	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BVG89_10510	COG1737	Transcriptional regulator
BVG89_10525	COG1560	Kdo2-lipid A biosynthetic process
BVG89_10530	COG0739	heme binding
BVG89_10535	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BVG89_10540	COG1121	(ABC) transporter
BVG89_10545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BVG89_10550	COG2255	four-way junction helicase activity
BVG89_10555	COG0632	four-way junction helicase activity
BVG89_10560	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BVG89_10565	COG0217	transcriptional regulatory protein
BVG89_10570	COG0494	nUDIX hydrolase
BVG89_10575	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BVG89_10585	COG1335	isochorismatase
BVG89_10590	COG1801	Protein of unknown function DUF72
BVG89_10595	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BVG89_10600	COG2226	methyltransferase
BVG89_10605	COG0500	methyltransferase
BVG89_10610	COG0545	Peptidyl-prolyl cis-trans isomerase
BVG89_10625	COG3142	Participates in the control of copper homeostasis
BVG89_10630	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BVG89_10635	COG3102	Protein conserved in bacteria
BVG89_10640	COG0018	arginyl-trna synthetase
BVG89_10650	COG0673	inositol 2-dehydrogenase activity
BVG89_10655	COG3132	Protein of unknown function, DUF480
BVG89_10660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVG89_10665	COG0477	Major facilitator Superfamily
BVG89_10675	COG2999	glutathione oxidoreductase activity
BVG89_10700	COG3141	response to X-ray
BVG89_10705	COG0513	Belongs to the DEAD box helicase family
BVG89_10710	COG1278	Cold shock
BVG89_10715	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BVG89_10720	COG3140	Belongs to the UPF0181 family
BVG89_10725	COG1216	Glycosyl transferase, family 2
BVG89_10735	COG0494	nUDIX hydrolase
BVG89_10740	COG1760	l-serine dehydratase
BVG89_10745	COG2200	EAL domain
BVG89_10750	COG1253	flavin adenine dinucleotide binding
BVG89_10755	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVG89_10755	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVG89_10760	COG3715	PTS system
BVG89_10765	COG3716	PTS system mannose fructose sorbose family IID component
BVG89_10770	COG4811	Protein of unknown function (DUF986)
BVG89_10775	COG1971	Probably functions as a manganese efflux pump
BVG89_10780	COG2226	methyltransferase
BVG89_10790	COG1278	Cold shock
BVG89_10810	COG1113	amino acid transport
BVG89_10855	COG2207	Transcriptional regulator
BVG89_10870	COG1652	LysM domain
BVG89_10890	COG2988	succinylglutamate desuccinylase activity
BVG89_10895	COG3724	N-succinylarginine dihydrolase activity
BVG89_10900	COG1012	belongs to the aldehyde dehydrogenase family
BVG89_10905	COG3138	arginine N-succinyltransferase
BVG89_10910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BVG89_10920	COG4608	Belongs to the ABC transporter superfamily
BVG89_10925	COG0444	Belongs to the ABC transporter superfamily
BVG89_10935	COG0601	transmembrane transport
BVG89_10945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVG89_10950	COG1271	oxidase subunit
BVG89_10955	COG1294	oxidase, subunit
BVG89_11005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVG89_11010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BVG89_11015	COG2181	nitrate reductase activity
BVG89_11020	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BVG89_11025	COG1140	nitrate reductase beta subunit
BVG89_11030	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BVG89_11080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BVG89_11085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVG89_11090	COG3710	Transcriptional regulator
BVG89_11095	COG2223	nitrite transmembrane transporter activity
BVG89_11100	COG3850	Histidine kinase
BVG89_11105	COG2197	response regulator
BVG89_11110	COG4932	domain protein
BVG89_11115	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BVG89_11125	COG0747	negative chemotaxis
BVG89_11130	COG4608	Belongs to the ABC transporter superfamily
BVG89_11135	COG0444	Belongs to the ABC transporter superfamily
BVG89_11140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BVG89_11145	COG0601	transmembrane transport
BVG89_11155	COG0583	DNA-binding transcription factor activity
BVG89_11160	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BVG89_11165	COG4572	Cation transport regulator
BVG89_11170	COG2375	cellular response to nickel ion
BVG89_11175	COG0387	Pfam Sodium calcium exchanger
BVG89_11185	COG1702	phosphate starvation-inducible protein PhoH
BVG89_11210	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BVG89_11210	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BVG89_11210	COG0506	proline dehydrogenase activity
BVG89_11230	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BVG89_11240	COG1191	sigma factor activity
BVG89_11275	COG0583	DNA-binding transcription factor activity
BVG89_11290	COG1677	Flagellar hook-basal body complex protein FliE
BVG89_11300	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BVG89_11305	COG1317	bacterial-type flagellum organization
BVG89_11310	COG1157	protein secretion by the type III secretion system
BVG89_11315	COG2882	bacterial-type flagellum organization
BVG89_11350	COG1987	bacterial-type flagellum assembly
BVG89_11365	COG1256	bacterial-type flagellum assembly
BVG89_11390	COG4786	Flagellar basal body rod
BVG89_11400	COG1749	Flagellar hook protein flgE
BVG89_11405	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BVG89_11410	COG1558	bacterial-type flagellum-dependent cell motility
BVG89_11415	COG1815	bacterial-type flagellum-dependent cell motility
BVG89_11425	COG2747	anti-sigma28 factor FlgM
BVG89_11430	COG3418	PFAM FlgN family protein
BVG89_11450	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BVG89_11455	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BVG89_11460	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BVG89_11465	COG0745	RESPONSE REGULATOR receiver
BVG89_11475	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BVG89_11480	COG0840	transmembrane signaling receptor activity
BVG89_11485	COG0840	transmembrane signaling receptor activity
BVG89_11490	COG0835	chemotaxis
BVG89_11495	COG0643	Histidine kinase
BVG89_11495	COG2198	Histidine kinase
BVG89_11525	COG0589	response to stress
BVG89_11530	COG2130	NADP-dependent
BVG89_11535	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BVG89_11545	COG3501	Rhs element vgr protein
BVG89_11710	COG3501	Rhs element vgr protein
BVG89_11740	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BVG89_11745	COG3483	tryptophan 2,3-dioxygenase activity
BVG89_11750	COG1609	Transcriptional regulator
BVG89_11800	COG2814	Major facilitator Superfamily
BVG89_11825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BVG89_11835	COG3712	iron ion homeostasis
BVG89_11840	COG1595	DNA-templated transcription, initiation
BVG89_11845	COG1629	transport
BVG89_11850	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BVG89_11880	COG0583	DNA-binding transcription factor activity
BVG89_11895	COG3781	membrane
BVG89_11900	COG2837	iron assimilation
BVG89_11905	COG1393	Belongs to the ArsC family
BVG89_11910	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BVG89_11920	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BVG89_11945	COG1285	pathogenesis
BVG89_11950	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BVG89_11960	COG0076	glutamate decarboxylase activity
BVG89_11985	COG1278	Cold shock
BVG89_12000	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_12000	COG0604	alcohol dehydrogenase
BVG89_12000	COG3321	synthase
BVG89_12010	COG0583	DNA-binding transcription factor activity
BVG89_12015	COG3753	Protein conserved in bacteria
BVG89_12020	COG2261	transglycosylase associated protein
BVG89_12030	COG1560	Kdo2-lipid A biosynthetic process
BVG89_12035	COG2764	glyoxalase bleomycin resistance protein dioxygenase
BVG89_12045	COG5001	Diguanylate cyclase
BVG89_12045	COG4251	negative regulation of phosphorylation
BVG89_12045	COG3706	GGDEF domain
BVG89_12045	COG2203	Gaf domain
BVG89_12055	COG1012	belongs to the aldehyde dehydrogenase family
BVG89_12055	COG2030	dehydratase
BVG89_12060	COG3396	Phenylacetate-CoA oxygenase
BVG89_12065	COG3460	Phenylacetate-CoA oxygenase
BVG89_12070	COG3396	Phenylacetate-CoA oxygenase
BVG89_12075	COG2151	metal-sulfur cluster biosynthetic enzyme
BVG89_12080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BVG89_12085	COG1024	Enoyl-CoA hydratase
BVG89_12090	COG1024	Enoyl-CoA hydratase
BVG89_12095	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVG89_12100	COG2050	protein possibly involved in aromatic compounds catabolism
BVG89_12105	COG0183	Belongs to the thiolase family
BVG89_12110	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BVG89_12115	COG3327	negative regulation of DNA-templated transcription, initiation
BVG89_12120	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BVG89_12125	COG1113	amino acid transport
BVG89_12130	COG1448	Aminotransferase
BVG89_12145	COG0583	DNA-binding transcription factor activity
BVG89_12150	COG0625	glutathione transferase activity
BVG89_12190	COG0667	Aldo Keto reductase
BVG89_12195	COG4772	TonB-dependent receptor
BVG89_12200	COG4993	Dehydrogenase
BVG89_12215	COG0534	Mate efflux family protein
BVG89_12255	COG3228	Belongs to the MtfA family
BVG89_12265	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BVG89_12270	COG4977	sequence-specific DNA binding
BVG89_12280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVG89_12285	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BVG89_12290	COG1116	anion transmembrane transporter activity
BVG89_12295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVG89_12300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVG89_12315	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BVG89_12330	COG3238	Protein conserved in bacteria
BVG89_12335	COG1247	-acetyltransferase
BVG89_12355	COG0583	DNA-binding transcription factor activity
BVG89_12370	COG2814	Major facilitator Superfamily
BVG89_12380	COG2011	ABC-type metal ion transport system permease component
BVG89_12400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVG89_12405	COG3829	transcription factor binding
BVG89_12410	COG1802	Transcriptional regulator
BVG89_12430	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_12435	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_12455	COG0859	PFAM glycosyl transferase family 9
BVG89_12475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVG89_12480	COG4172	Belongs to the ABC transporter superfamily
BVG89_12495	COG0747	negative chemotaxis
BVG89_12505	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BVG89_12525	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_12530	COG1169	isochorismate synthase
BVG89_12545	COG0471	metal ion transport
BVG89_12550	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BVG89_12560	COG3051	citrate lyase alpha subunit
BVG89_12565	COG2301	Belongs to the HpcH HpaI aldolase family
BVG89_12570	COG3052	prosthetic group binding
BVG89_12575	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
BVG89_12580	COG4565	transcriptional regulatory protein
BVG89_12585	COG3250	beta-galactosidase activity
BVG89_12600	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BVG89_12605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVG89_12610	COG3414	Phosphotransferase system galactitol-specific IIB component
BVG89_12615	COG3775	system Galactitol-specific IIC component
BVG89_12625	COG1349	DNA-binding transcription factor activity
BVG89_12635	COG3414	Phosphotransferase system galactitol-specific IIB component
BVG89_12640	COG3775	system Galactitol-specific IIC component
BVG89_12645	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BVG89_12650	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_12655	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BVG89_12670	COG2197	response regulator
BVG89_12680	COG1121	(ABC) transporter
BVG89_12700	COG2814	Major facilitator Superfamily
BVG89_12705	COG0860	N-Acetylmuramoyl-L-alanine amidase
BVG89_12725	COG1012	belongs to the aldehyde dehydrogenase family
BVG89_12730	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BVG89_12750	COG2070	2-Nitropropane dioxygenase
BVG89_12770	COG2271	Major facilitator Superfamily
BVG89_12795	COG0410	ABC transporter
BVG89_12800	COG0411	ABC transporter
BVG89_12850	COG0583	DNA-binding transcription factor activity
BVG89_12860	COG0456	acetyltransferase
BVG89_12875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVG89_12880	COG0156	8-amino-7-oxononanoate synthase activity
BVG89_12885	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BVG89_12890	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BVG89_12895	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BVG89_12900	COG2244	polysaccharide biosynthetic process
BVG89_12910	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BVG89_12915	COG0795	lipopolysaccharide-transporting ATPase activity
BVG89_12925	COG0463	Glycosyl transferase, family 2
BVG89_12935	COG0583	DNA-binding transcription factor activity
BVG89_12950	COG1609	Transcriptional regulator
BVG89_12960	COG3623	hexulose-6-phosphate isomerase
BVG89_12965	COG1070	Carbohydrate kinase
BVG89_12970	COG1172	Belongs to the binding-protein-dependent transport system permease family
BVG89_12980	COG1879	ABC-type sugar transport system periplasmic component
BVG89_12985	COG1063	alcohol dehydrogenase
BVG89_12990	COG2926	Belongs to the UPF0265 family
BVG89_12995	COG1289	transmembrane transporter activity
BVG89_13000	COG3023	N-Acetylmuramoyl-L-alanine amidase
BVG89_13025	COG2925	Exonuclease
BVG89_13030	COG0531	amino acid
BVG89_13040	COG0174	glutamine synthetase
BVG89_13045	COG1396	sequence-specific DNA binding
BVG89_13045	COG1917	Cupin 2, conserved barrel domain protein
BVG89_13050	COG1129	ABC transporter
BVG89_13055	COG1172	Belongs to the binding-protein-dependent transport system permease family
BVG89_13060	COG4771	TonB-dependent receptor
BVG89_13075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVG89_13080	COG3706	GGDEF domain
BVG89_13085	COG0833	amino acid
BVG89_13090	COG0583	DNA-binding transcription factor activity
BVG89_13100	COG2855	membrane
BVG89_13105	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BVG89_13115	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BVG89_13115	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BVG89_13115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BVG89_13120	COG1105	Belongs to the carbohydrate kinase PfkB family
BVG89_13125	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVG89_13125	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVG89_13130	COG0494	nUDIX hydrolase
BVG89_13135	COG3005	denitrification pathway
BVG89_13140	COG0243	molybdopterin cofactor binding
BVG89_13160	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BVG89_13165	COG1312	Catalyzes the dehydration of D-mannonate
BVG89_13170	COG0246	Mannitol dehydrogenase
BVG89_13180	COG0523	cobalamin synthesis protein
BVG89_13185	COG0671	phosphoesterase, PA-phosphatase related
BVG89_13195	COG0791	NLP P60 protein
BVG89_13200	COG2200	EAL domain
BVG89_13205	COG4166	transmembrane transport
BVG89_13210	COG4174	ABC transporter (Permease)
BVG89_13215	COG4239	(ABC) transporter, permease
BVG89_13220	COG4172	Belongs to the ABC transporter superfamily
BVG89_13230	COG2814	Major facilitator Superfamily
BVG89_13235	COG1187	pseudouridine synthase activity
BVG89_13240	COG1061	Type III restriction enzyme res subunit
BVG89_13245	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BVG89_13250	COG3081	Nucleoid-associated protein
BVG89_13255	COG3082	Protein of unknown function (DUF1414)
BVG89_13260	COG3083	sulfuric ester hydrolase activity
BVG89_13275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVG89_13280	COG0625	glutathione transferase activity
BVG89_13295	COG2271	Major facilitator Superfamily
BVG89_13335	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BVG89_13365	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BVG89_13380	COG0346	lactoylglutathione lyase activity
BVG89_13395	COG2223	nitrite transmembrane transporter activity
BVG89_13400	COG0642	Histidine kinase
BVG89_13400	COG2198	Histidine kinase
BVG89_13405	COG2197	response regulator
BVG89_13410	COG2205	protein histidine kinase activity
BVG89_13410	COG0784	Response regulator, receiver
BVG89_13420	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BVG89_13425	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BVG89_13435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BVG89_13460	COG0814	amino acid
BVG89_13475	COG0318	PFAM AMP-dependent synthetase and ligase
BVG89_13485	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BVG89_13490	COG0596	Alpha beta hydrolase
BVG89_13495	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BVG89_13500	COG4575	ribosome binding
BVG89_13505	COG1063	alcohol dehydrogenase
BVG89_13510	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_13525	COG0583	DNA-binding transcription factor activity
BVG89_13530	COG1007	ATP synthesis coupled electron transport
BVG89_13535	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVG89_13540	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BVG89_13545	COG0713	ATP synthesis coupled electron transport
BVG89_13550	COG0839	Belongs to the complex I subunit 6 family
BVG89_13560	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BVG89_13565	COG1034	ATP synthesis coupled electron transport
BVG89_13575	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BVG89_13580	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVG89_13580	COG0649	NAD binding
BVG89_13585	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVG89_13590	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVG89_13595	COG0583	DNA-binding transcription factor activity
BVG89_13600	COG0436	Aminotransferase
BVG89_13605	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BVG89_13610	COG0490	domain, Protein
BVG89_13610	COG0471	metal ion transport
BVG89_13615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BVG89_13620	COG3013	Belongs to the UPF0304 family
BVG89_13625	COG3092	negative regulation of chromosome organization
BVG89_13630	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BVG89_13635	COG0280	phosphate acetyltransferase
BVG89_13635	COG0857	belongs to the CobB CobQ family
BVG89_13650	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BVG89_13655	COG3959	Transketolase, thiamine diphosphate binding domain
BVG89_13660	COG3037	sugar-specific permease SgaT UlaA
BVG89_13670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVG89_13675	COG1609	Transcriptional regulator
BVG89_13680	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BVG89_13685	COG0622	Phosphoesterase
BVG89_13690	COG0625	glutathione transferase activity
BVG89_13695	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BVG89_13700	COG1090	epimerase
BVG89_13705	COG4598	ABC transporter
BVG89_13710	COG4160	amino acid transport
BVG89_13715	COG4215	(ABC) transporter
BVG89_13720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVG89_13725	COG0163	prenyltransferase activity
BVG89_13730	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BVG89_13735	COG1286	toxin biosynthetic process
BVG89_13740	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BVG89_13745	COG0285	dihydrofolate synthase activity
BVG89_13750	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BVG89_13755	COG0586	Pfam SNARE associated Golgi protein
BVG89_13765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BVG89_13770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BVG89_13780	COG0697	spore germination
BVG89_13785	COG0642	Histidine kinase
BVG89_13825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVG89_13830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVG89_13870	COG2195	Cleaves the N-terminal amino acid of tripeptides
BVG89_13875	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BVG89_13890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BVG89_13895	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BVG89_13895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVG89_13905	COG3101	peptidyl-lysine hydroxylation
BVG89_13910	COG0730	response to heat
BVG89_13920	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BVG89_13925	COG2890	protein-(glutamine-N5) methyltransferase activity
BVG89_13930	COG2840	Smr protein MutS2
BVG89_13935	COG2062	phosphohistidine phosphatase, SixA
BVG89_13940	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVG89_13940	COG1024	Enoyl-CoA hydratase
BVG89_13945	COG0183	Belongs to the thiolase family
BVG89_13950	COG3691	Protein conserved in bacteria
BVG89_13965	COG4235	cytochrome complex assembly
BVG89_13965	COG3088	subunit of a heme lyase
BVG89_13970	COG3088	subunit of a heme lyase
BVG89_13970	COG4235	cytochrome complex assembly
BVG89_13975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVG89_13980	COG1138	Cytochrome C-type biogenesis protein
BVG89_13985	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BVG89_13990	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BVG89_13995	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BVG89_14000	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BVG89_14010	COG2116	formate transmembrane transporter activity
BVG89_14020	COG0582	viral genome integration into host DNA
BVG89_14075	COG2706	6-phosphogluconolactonase activity
BVG89_14080	COG2207	Transcriptional regulator
BVG89_14080	COG3708	Transcriptional regulator
BVG89_14095	COG2197	response regulator
BVG89_14105	COG0583	DNA-binding transcription factor activity
BVG89_14115	COG0697	spore germination
BVG89_14130	COG2951	lytic endotransglycosylase activity
BVG89_14140	COG1598	PFAM Uncharacterised protein family UPF0150
BVG89_14145	COG3038	cytochrome b561
BVG89_14150	COG0436	Aminotransferase
BVG89_14165	COG3275	phosphorelay sensor kinase activity
BVG89_14170	COG3279	Response regulator of the LytR AlgR family
BVG89_14180	COG2223	nitrite transmembrane transporter activity
BVG89_14190	COG0038	chloride channel
BVG89_14195	COG1794	racemase activity, acting on amino acids and derivatives
BVG89_14210	COG3961	Belongs to the TPP enzyme family
BVG89_14215	COG0667	Aldo Keto reductase
BVG89_14225	COG1914	H( )-stimulated, divalent metal cation uptake system
BVG89_14230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BVG89_14245	COG2116	formate transmembrane transporter activity
BVG89_14250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BVG89_14285	COG4592	Periplasmic binding protein
BVG89_14290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVG89_14295	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVG89_14300	COG1120	ATPase activity
BVG89_14305	COG0747	negative chemotaxis
BVG89_14325	COG4302	ethanolamine ammonia-lyase activity
BVG89_14330	COG4303	Ethanolamine ammonia lyase large subunit
BVG89_14345	COG0583	DNA-binding transcription factor activity
BVG89_14350	COG0385	Bile acid
BVG89_14355	COG3530	Putative quorum-sensing-regulated virulence factor
BVG89_14360	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BVG89_14365	COG3115	cell septum assembly
BVG89_14370	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BVG89_14375	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BVG89_14380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVG89_14385	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BVG89_14390	COG2190	(PTS) system
BVG89_14395	COG2205	protein histidine kinase activity
BVG89_14400	COG0745	RESPONSE REGULATOR receiver
BVG89_14415	COG4208	sulfate ABC transporter
BVG89_14420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BVG89_14430	COG2837	iron assimilation
BVG89_14445	COG3111	PFAM Bacterial OB fold (BOF) protein
BVG89_14450	COG0456	acetyltransferase
BVG89_14455	COG0860	N-Acetylmuramoyl-L-alanine amidase
BVG89_14460	COG0408	coproporphyrinogen oxidase activity
BVG89_14465	COG1671	Belongs to the UPF0178 family
BVG89_14480	COG0833	amino acid
BVG89_14495	COG1770	oligopeptidase
BVG89_14510	COG0833	amino acid
BVG89_14515	COG2040	homocysteine
BVG89_14555	COG0583	DNA-binding transcription factor activity
BVG89_14560	COG3397	chitin binding
BVG89_14575	COG2376	Dihydroxyacetone kinase
BVG89_14580	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_14585	COG2814	Major facilitator Superfamily
BVG89_14590	COG1063	alcohol dehydrogenase
BVG89_14595	COG0698	ribose 5-phosphate isomerase
BVG89_14600	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BVG89_14605	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BVG89_14610	COG0494	nUDIX hydrolase
BVG89_14615	COG3850	Histidine kinase
BVG89_14620	COG2197	response regulator
BVG89_14630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVG89_14645	COG0454	-acetyltransferase
BVG89_14655	COG1393	Belongs to the ArsC family
BVG89_14660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BVG89_14665	COG1876	peptidase activity
BVG89_14675	COG0400	carboxylic ester hydrolase activity
BVG89_14680	COG1444	tRNA N-acetyltransferase activity
BVG89_14685	COG2321	neutral zinc metallopeptidase
BVG89_14690	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BVG89_14695	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BVG89_14700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVG89_14705	COG2716	regulation of RNA biosynthetic process
BVG89_14710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BVG89_14715	COG0628	permease
BVG89_14760	COG4783	chaperone-mediated protein folding
BVG89_14765	COG1393	Belongs to the ArsC family
BVG89_14775	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BVG89_14785	COG2261	transglycosylase associated protein
BVG89_14790	COG2233	PERMEase
BVG89_14795	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BVG89_14800	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BVG89_14805	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BVG89_14810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVG89_14870	COG0573	inorganic phosphate transmembrane transporter activity
BVG89_14875	COG0573	inorganic phosphate transmembrane transporter activity
BVG89_14880	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BVG89_14885	COG0248	Ppx GppA phosphatase
BVG89_14895	COG2239	Acts as a magnesium transporter
BVG89_14900	COG5002	protein histidine kinase activity
BVG89_14900	COG5001	Diguanylate cyclase
BVG89_14900	COG3447	MASE1 domain protein
BVG89_14915	COG0443	Heat shock 70 kDa protein
BVG89_14930	COG0667	Aldo Keto reductase
BVG89_14935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVG89_14940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVG89_14945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVG89_14950	COG2814	Major facilitator Superfamily
BVG89_14955	COG2205	protein histidine kinase activity
BVG89_14960	COG0745	RESPONSE REGULATOR receiver
BVG89_14975	COG3422	double-strand break repair
BVG89_14985	COG1597	lipid kinase activity
BVG89_14995	COG1063	alcohol dehydrogenase
BVG89_15000	COG2271	Major facilitator Superfamily
BVG89_15005	COG0246	Mannitol dehydrogenase
BVG89_15015	COG1802	Transcriptional regulator
BVG89_15020	COG1830	Aldolase
BVG89_15030	COG3730	PTS system glucitol sorbitol-specific
BVG89_15045	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_15050	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVG89_15055	COG1349	DNA-binding transcription factor activity
BVG89_15070	COG0351	phosphomethylpyrimidine kinase
BVG89_15075	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BVG89_15095	COG1289	transmembrane transporter activity
BVG89_15105	COG2814	Major facilitator Superfamily
BVG89_15115	COG1187	pseudouridine synthase activity
BVG89_15135	COG2198	Histidine kinase
BVG89_15135	COG0784	Response regulator, receiver
BVG89_15135	COG2205	protein histidine kinase activity
BVG89_15145	COG1733	regulation of RNA biosynthetic process
BVG89_15160	COG0519	Catalyzes the synthesis of GMP from XMP
BVG89_15160	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BVG89_15165	COG0517	IMP dehydrogenase activity
BVG89_15165	COG0516	GMP reductase activity
BVG89_15170	COG1570	exodeoxyribonuclease VII activity
BVG89_15180	COG2271	Major facilitator Superfamily
BVG89_15185	COG1609	Transcriptional regulator
BVG89_15200	COG1645	bacterial-type flagellum-dependent swarming motility
BVG89_15210	COG1160	GTP binding
BVG89_15215	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BVG89_15220	COG2976	Protein conserved in bacteria
BVG89_15225	COG0124	histidyl-tRNA synthetase
BVG89_15230	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BVG89_15235	COG1426	Protein conserved in bacteria
BVG89_15245	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BVG89_15250	COG0105	UTP biosynthetic process
BVG89_15260	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BVG89_15265	COG2975	iron-sulfur cluster assembly
BVG89_15270	COG0633	Ferredoxin
BVG89_15275	COG0443	Heat shock 70 kDa protein
BVG89_15280	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BVG89_15285	COG0316	Belongs to the HesB IscA family
BVG89_15290	COG0822	iron-sulfur transferase activity
BVG89_15295	COG1104	cysteine desulfurase activity
BVG89_15300	COG1959	2 iron, 2 sulfur cluster binding
BVG89_15315	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BVG89_15320	COG3683	transport system, periplasmic component
BVG89_15325	COG3711	transcriptional antiterminator
BVG89_15330	COG2814	Major facilitator Superfamily
BVG89_15335	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BVG89_15340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BVG89_15340	COG1017	nitric oxide dioxygenase activity
BVG89_15350	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BVG89_15355	COG1012	belongs to the aldehyde dehydrogenase family
BVG89_15360	COG1177	transmembrane transport
BVG89_15365	COG1176	ABC-type spermidine putrescine transport system, permease component I
BVG89_15370	COG3842	ATPase activity
BVG89_15375	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BVG89_15385	COG0583	DNA-binding transcription factor activity
BVG89_15390	COG0347	Belongs to the P(II) protein family
BVG89_15395	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BVG89_15395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVG89_15400	COG2204	response regulator
BVG89_15405	COG3170	Tfp pilus assembly protein FimV
BVG89_15410	COG2205	protein histidine kinase activity
BVG89_15420	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BVG89_15425	COG0590	tRNA wobble adenosine to inosine editing
BVG89_15435	COG0560	Phosphoserine phosphatase
BVG89_15440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVG89_15440	COG1263	PTS System
BVG89_15445	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BVG89_15450	COG1737	Transcriptional regulator
BVG89_15455	COG2194	sulfuric ester hydrolase activity
BVG89_15460	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BVG89_15465	COG0736	holo-[acyl-carrier-protein] synthase activity
BVG89_15470	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BVG89_15475	COG1381	Involved in DNA repair and RecF pathway recombination
BVG89_15480	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BVG89_15485	COG0571	ribonuclease III activity
BVG89_15490	COG0681	Belongs to the peptidase S26 family
BVG89_15495	COG0481	GTPase activity
BVG89_15505	COG3086	response to oxidative stress
BVG89_15510	COG3026	antisigma factor binding
BVG89_15525	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BVG89_15530	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BVG89_15535	COG0513	Belongs to the DEAD box helicase family
BVG89_15555	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BVG89_15560	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BVG89_15565	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BVG89_15570	COG0497	DNA recombination
BVG89_15575	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BVG89_15580	COG2914	Belongs to the UPF0125 (RnfH) family
BVG89_15585	COG2867	negative regulation of translational initiation
BVG89_15590	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BVG89_15605	COG3182	Iron-regulated membrane protein
BVG89_15620	COG2264	protein methyltransferase activity
BVG89_15645	COG2388	GCN5-related N-acetyl-transferase
BVG89_15650	COG3592	Divergent 4Fe-4S mono-cluster
BVG89_15655	COG2259	Doxx family
BVG89_15660	COG2840	Smr protein MutS2
BVG89_15680	COG0477	Major facilitator Superfamily
BVG89_15690	COG0477	Major facilitator Superfamily
BVG89_15705	COG4575	ribosome binding
BVG89_15715	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BVG89_15720	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BVG89_15725	COG1780	Probably involved in ribonucleotide reductase function
BVG89_15755	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_15760	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BVG89_15765	COG1752	Esterase of the alpha-beta hydrolase superfamily
BVG89_15770	COG3493	citrate carrier protein
BVG89_15790	COG4176	ABC-type proline glycine betaine transport system permease component
BVG89_15795	COG2113	Glycine betaine
BVG89_15800	COG0583	DNA-binding transcription factor activity
BVG89_15805	COG2814	Major facilitator Superfamily
BVG89_15810	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BVG89_15820	COG1846	Transcriptional regulator
BVG89_15830	COG1566	PFAM secretion protein HlyD family protein
BVG89_15835	COG2814	Major facilitator Superfamily
BVG89_15840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BVG89_15845	COG3118	belongs to the thioredoxin family
BVG89_15855	COG1042	CoA-binding domain protein
BVG89_15855	COG0045	succinate-CoA ligase (ADP-forming) activity
BVG89_15855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVG89_15860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVG89_15865	COG0477	Major facilitator Superfamily
BVG89_15900	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BVG89_15910	COG2011	ABC-type metal ion transport system permease component
BVG89_15925	COG1720	tRNA m6t6A37 methyltransferase activity
BVG89_15930	COG0442	prolyl-tRNA aminoacylation
BVG89_15935	COG3015	lipoprotein NlpE involved in copper resistance
BVG89_15940	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BVG89_15945	COG4681	YaeQ
BVG89_15955	COG4568	rho-dependent transcription termination
BVG89_15965	COG0037	tRNA processing
BVG89_15970	COG3104	oligopeptide transport
BVG89_15975	COG1982	Orn Lys Arg decarboxylase major
BVG89_15980	COG0531	amino acid
BVG89_15985	COG3710	Transcriptional regulator
BVG89_15990	COG0346	lactoylglutathione lyase activity
BVG89_16010	COG0825	malonyl-CoA metabolic process
BVG89_16015	COG0587	DNA-directed DNA polymerase activity
BVG89_16020	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BVG89_16025	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVG89_16030	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVG89_16040	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVG89_16045	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BVG89_16050	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BVG89_16055	COG0750	zinc metalloprotease
BVG89_16060	COG0575	Belongs to the CDS family
BVG89_16065	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BVG89_16070	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BVG89_16075	COG0233	cytoplasmic translational termination
BVG89_16080	COG0528	UMP kinase activity
BVG89_16090	COG0052	Belongs to the universal ribosomal protein uS2 family
BVG89_16095	COG0024	Methionine aminopeptidase
BVG89_16100	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BVG89_16120	COG0564	pseudouridine synthase activity
BVG89_16125	COG4953	penicillin-binding protein 1C
BVG89_16130	COG2373	Large extracellular alpha-helical protein
BVG89_16135	COG3098	single-species biofilm formation
BVG89_16140	COG2814	Major facilitator Superfamily
BVG89_16155	COG1611	Belongs to the LOG family
BVG89_16160	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BVG89_16165	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BVG89_16170	COG2363	Small membrane protein
BVG89_16175	COG0583	DNA-binding transcription factor activity
BVG89_16185	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BVG89_16190	COG2166	iron-sulfur cluster assembly
BVG89_16195	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BVG89_16200	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BVG89_16220	COG0860	N-Acetylmuramoyl-L-alanine amidase
BVG89_16225	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BVG89_16225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BVG89_16230	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BVG89_16235	COG1074	ATP-dependent DNA helicase activity
BVG89_16240	COG1025	Belongs to the peptidase M16 family
BVG89_16245	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BVG89_16265	COG2165	general secretion pathway protein
BVG89_16270	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BVG89_16275	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BVG89_16285	COG0494	nUDIX hydrolase
BVG89_16290	COG3066	DNA modification
BVG89_16295	COG0861	Integral membrane protein TerC family
BVG89_16305	COG0667	Aldo Keto reductase
BVG89_16310	COG0477	Major facilitator Superfamily
BVG89_16315	COG0318	PFAM AMP-dependent synthetase and ligase
BVG89_16315	COG0204	Acyl-transferase
BVG89_16325	COG1609	Transcriptional regulator
BVG89_16340	COG0019	diaminopimelate decarboxylase activity
BVG89_16345	COG0583	DNA-binding transcription factor activity
BVG89_16350	COG0583	DNA-binding transcription factor activity
BVG89_16370	COG4178	(ABC) transporter
BVG89_16380	COG3716	PTS system mannose fructose sorbose family IID component
BVG89_16385	COG3715	PTS system
BVG89_16390	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVG89_16400	COG1349	DNA-binding transcription factor activity
BVG89_16405	COG2807	transmembrane transport
BVG89_16415	COG4615	Cyclic peptide transporter
BVG89_16425	COG1620	l-lactate permease
BVG89_16430	COG1304	FMN binding
BVG89_16455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BVG89_16460	COG1309	transcriptional regulator
BVG89_16465	COG5265	(ABC) transporter
BVG89_16470	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BVG89_16475	COG4942	peptidase
BVG89_16480	COG1335	isochorismatase
BVG89_16485	COG0583	DNA-binding transcription factor activity
BVG89_16490	COG3247	response to pH
BVG89_16515	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BVG89_16520	COG1609	Transcriptional regulator
BVG89_16540	COG2731	YhcH YjgK YiaL family protein
BVG89_16545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BVG89_16550	COG2271	Major facilitator Superfamily
BVG89_16595	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BVG89_16615	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BVG89_16620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BVG89_16625	COG4974	Belongs to the 'phage' integrase family
BVG89_16630	COG0716	FMN binding
BVG89_16635	COG4452	Inner membrane protein CreD
BVG89_16640	COG2205	protein histidine kinase activity
BVG89_16645	COG0745	RESPONSE REGULATOR receiver
BVG89_16655	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BVG89_16660	COG0354	folic acid binding
BVG89_16670	COG1272	protein, Hemolysin III
BVG89_16680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVG89_16685	COG1940	carbohydrate kinase activity
BVG89_16690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BVG89_16700	COG1172	Belongs to the binding-protein-dependent transport system permease family
BVG89_16705	COG1129	ABC transporter
BVG89_16715	COG1349	DNA-binding transcription factor activity
BVG89_16755	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_16785	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BVG89_16785	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BVG89_16790	COG0509	glycine decarboxylation via glycine cleavage system
BVG89_16795	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BVG89_16800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVG89_16805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVG89_16810	COG0006	proline dipeptidase activity
BVG89_16815	COG3079	Belongs to the UPF0149 family
BVG89_16820	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BVG89_16830	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BVG89_16835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BVG89_16840	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BVG89_16845	COG0583	DNA-binding transcription factor activity
BVG89_16855	COG1279	arginine transmembrane transporter activity
BVG89_16860	COG1414	Transcriptional regulator
BVG89_16865	COG1129	ABC transporter
BVG89_16870	COG1172	Belongs to the binding-protein-dependent transport system permease family
BVG89_16890	COG2731	YhcH YjgK YiaL family protein
BVG89_16900	COG1070	Carbohydrate kinase
BVG89_16905	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BVG89_16910	COG3623	hexulose-6-phosphate isomerase
BVG89_16915	COG0235	Class ii aldolase
BVG89_16925	COG3122	Protein conserved in bacteria
BVG89_16940	COG2271	Major facilitator Superfamily
BVG89_16955	COG0191	fructose-bisphosphate aldolase activity
BVG89_16960	COG0126	phosphoglycerate kinase activity
BVG89_16965	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BVG89_16970	COG0583	DNA-binding transcription factor activity
BVG89_16975	COG0473	3-isopropylmalate dehydrogenase activity
BVG89_16980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BVG89_16985	COG4638	Rieske (2fe-2S)
BVG89_16995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BVG89_17000	COG3842	ATPase activity
BVG89_17005	COG1175	transmembrane transport
BVG89_17020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVG89_17030	COG1114	Component of the transport system for branched-chain amino acids
BVG89_17035	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BVG89_17040	COG0501	Belongs to the peptidase M48B family
BVG89_17055	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BVG89_17060	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_17065	COG2267	carboxylic ester hydrolase activity
BVG89_17090	COG1414	Transcriptional regulator
BVG89_17095	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_17110	COG2146	nitrite reductase [NAD(P)H] activity
BVG89_17115	COG2271	Major facilitator Superfamily
BVG89_17125	COG0010	Belongs to the arginase family
BVG89_17180	COG1166	arginine decarboxylase activity
BVG89_17185	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BVG89_17195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVG89_17200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BVG89_17205	COG1120	ATPase activity
BVG89_17210	COG4774	siderophore transport
BVG89_17215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVG89_17220	COG1643	Atp-dependent helicase
BVG89_17225	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BVG89_17230	COG1489	DNA binding
BVG89_17240	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BVG89_17245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BVG89_17250	COG0617	tRNA 3'-terminal CCA addition
BVG89_17255	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BVG89_17260	COG0642	Histidine kinase
BVG89_17265	COG0745	RESPONSE REGULATOR receiver
BVG89_17270	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BVG89_17275	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BVG89_17280	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BVG89_17285	COG0726	polysaccharide deacetylase
BVG89_17290	COG0842	Transport permease protein
BVG89_17295	COG1131	(ABC) transporter
BVG89_17300	COG0288	reversible hydration of carbon dioxide
BVG89_17310	COG2132	Multicopper oxidase
BVG89_17320	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BVG89_17325	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BVG89_17330	COG3112	Uncharacterised protein family (UPF0231)
BVG89_17340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVG89_17345	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVG89_17350	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BVG89_17355	COG2186	Transcriptional regulator
BVG89_17360	COG1113	amino acid transport
BVG89_17365	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BVG89_17365	COG2010	Cytochrome c
BVG89_17375	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BVG89_17375	COG2010	Cytochrome c
BVG89_17385	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BVG89_17390	COG2207	Transcriptional regulator
BVG89_17390	COG3708	Transcriptional regulator
BVG89_17400	COG3091	SprT-like family
BVG89_17405	COG2356	endonuclease I
BVG89_17410	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BVG89_17415	COG0189	ligase activity
BVG89_17420	COG1678	Uncharacterized ACR, COG1678
BVG89_17425	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BVG89_17430	COG2805	Type II/IV secretion system protein
BVG89_17435	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BVG89_17440	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BVG89_17445	COG0762	integral membrane protein
BVG89_17450	COG1872	DUF167
BVG89_17460	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BVG89_17480	COG2066	Belongs to the glutaminase family
BVG89_17485	COG3171	Protein conserved in bacteria
BVG89_17490	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BVG89_17500	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BVG89_17505	COG0741	lytic transglycosylase activity
BVG89_17510	COG1982	Orn Lys Arg decarboxylase major
BVG89_17520	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BVG89_17560	COG4584	PFAM Integrase catalytic
BVG89_17775	COG0629	single-stranded DNA binding
BVG89_17785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BVG89_17810	COG2226	methyltransferase
BVG89_17825	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BVG89_17830	COG0477	Major facilitator Superfamily
BVG89_17865	COG0305	Participates in initiation and elongation during chromosome replication
BVG89_17905	COG2819	hydrolase of the alpha beta superfamily
BVG89_17910	COG0454	-acetyltransferase
BVG89_17935	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BVG89_17935	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BVG89_17950	COG4772	TonB-dependent receptor
BVG89_17955	COG0583	DNA-binding transcription factor activity
BVG89_17960	COG1473	amidohydrolase
BVG89_17965	COG1473	amidohydrolase
BVG89_17970	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BVG89_18000	COG0848	biopolymer transport protein
BVG89_18005	COG0811	peptide transport
BVG89_18015	COG0586	Pfam SNARE associated Golgi protein
BVG89_18025	COG3321	synthase
BVG89_18025	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_18025	COG0604	alcohol dehydrogenase
BVG89_18030	COG2207	Transcriptional regulator
BVG89_18035	COG1979	alcohol dehydrogenase
BVG89_18040	COG0656	L-ascorbic acid biosynthetic process
BVG89_18055	COG2186	Transcriptional regulator
BVG89_18065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVG89_18070	COG2211	Major facilitator Superfamily
BVG89_18075	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BVG89_18080	COG0583	DNA-binding transcription factor activity
BVG89_18085	COG2132	Multicopper oxidase
BVG89_18090	COG0204	Acyl-transferase
BVG89_18095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BVG89_18100	COG2249	NAD(P)H dehydrogenase (quinone) activity
BVG89_18105	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BVG89_18110	COG0583	DNA-binding transcription factor activity
BVG89_18115	COG0187	DNA topoisomerase II activity
BVG89_18120	COG3150	esterase
BVG89_18125	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BVG89_18130	COG3151	Protein conserved in bacteria
BVG89_18135	COG0494	nUDIX hydrolase
BVG89_18140	COG1538	Outer membrane efflux protein
BVG89_18150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BVG89_18150	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BVG89_18150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVG89_18155	COG1461	Dihydroxyacetone kinase
BVG89_18160	COG2376	Dihydroxyacetone kinase
BVG89_18170	COG5463	Belongs to the UPF0441 family
BVG89_18175	COG0754	glutathionylspermidine amidase activity
BVG89_18180	COG3384	dioxygenase
BVG89_18190	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BVG89_18200	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BVG89_18200	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BVG89_18205	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BVG89_18210	COG3025	triphosphatase activity
BVG89_18215	COG4991	sh3 domain protein
BVG89_18220	COG0617	tRNA 3'-terminal CCA addition
BVG89_18225	COG1968	undecaprenyl-diphosphatase activity
BVG89_18230	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BVG89_18235	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BVG89_18240	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BVG89_18250	COG0358	DNA primase activity
BVG89_18255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BVG89_18275	COG1733	regulation of RNA biosynthetic process
BVG89_18280	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BVG89_18310	COG0625	glutathione transferase activity
BVG89_18320	COG1012	belongs to the aldehyde dehydrogenase family
BVG89_18325	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BVG89_18335	COG0488	(ABC) transporter
BVG89_18340	COG1902	pentaerythritol trinitrate reductase activity
BVG89_18340	COG0446	pyridine nucleotide-disulphide oxidoreductase
BVG89_18345	COG2813	Specifically methylates the guanine in position
BVG89_18350	COG1451	nucleotide metabolic process
BVG89_18355	COG0673	inositol 2-dehydrogenase activity
BVG89_18360	COG0519	Catalyzes the synthesis of GMP from XMP
BVG89_18360	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BVG89_18365	COG0861	Integral membrane protein TerC family
BVG89_18370	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BVG89_18375	COG2721	sulfolactate sulfo-lyase activity
BVG89_18380	COG1904	glucuronate isomerase
BVG89_18385	COG2271	Major facilitator Superfamily
BVG89_18400	COG0586	Pfam SNARE associated Golgi protein
BVG89_18405	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BVG89_18415	COG4575	ribosome binding
BVG89_18420	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
BVG89_18430	COG2259	Doxx family
BVG89_18435	COG0435	Glutathione S-transferase
BVG89_18440	COG0583	DNA-binding transcription factor activity
BVG89_18445	COG1741	Belongs to the pirin family
BVG89_18455	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BVG89_18460	COG3107	peptidoglycan biosynthetic process
BVG89_18465	COG0792	nuclease activity
BVG89_18470	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BVG89_18475	COG2823	Periplasmic or secreted lipoprotein
BVG89_18485	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BVG89_18490	COG2198	Histidine kinase
BVG89_18490	COG0784	Response regulator, receiver
BVG89_18490	COG5002	protein histidine kinase activity
BVG89_18495	COG1242	4 iron, 4 sulfur cluster binding
BVG89_18505	COG0067	glutamate synthase
BVG89_18505	COG0070	glutamate synthase
BVG89_18505	COG0069	glutamate synthase activity
BVG89_18510	COG0493	'glutamate synthase
BVG89_18520	COG2969	positive regulation of protein catabolic process
BVG89_18525	COG0625	glutathione transferase activity
BVG89_18530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BVG89_18535	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BVG89_18540	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BVG89_18545	COG3105	Protein conserved in bacteria
BVG89_18550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVG89_18555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVG89_18565	COG3210	domain, Protein
BVG89_18570	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BVG89_18575	COG5007	Belongs to the BolA IbaG family
BVG89_18580	COG3113	response to antibiotic
BVG89_18585	COG2854	intermembrane phospholipid transfer
BVG89_18590	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BVG89_18595	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BVG89_18600	COG1127	ABC transporter
BVG89_18605	COG0530	calcium, potassium:sodium antiporter activity
BVG89_18610	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BVG89_18610	COG0517	IMP dehydrogenase activity
BVG89_18615	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BVG89_18620	COG3117	lipopolysaccharide transmembrane transporter activity
BVG89_18625	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BVG89_18630	COG1137	ATPase activity
BVG89_18635	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BVG89_18645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVG89_18650	COG1660	Displays ATPase and GTPase activities
BVG89_18655	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVG89_18660	COG4680	protein conserved in bacteria
BVG89_18665	COG5499	transcription regulator containing HTH domain
BVG89_18670	COG3711	transcriptional antiterminator
BVG89_18670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVG89_18690	COG3964	amidohydrolase
BVG89_18720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BVG89_18730	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BVG89_18740	COG2207	Transcriptional regulator
BVG89_18745	COG3783	Cytochrome b(562)
BVG89_18750	COG0312	modulator of DNA gyrase
BVG89_18755	COG3028	Belongs to the UPF0307 family
BVG89_18760	COG2732	(Barnase) inhibitor
BVG89_18770	COG1289	transmembrane transporter activity
BVG89_18775	COG1566	PFAM secretion protein HlyD family protein
BVG89_18785	COG0583	DNA-binding transcription factor activity
BVG89_18800	COG1957	nucleoside hydrolase
BVG89_18810	COG2134	cdp-diacylglycerol pyrophosphatase
BVG89_18815	COG0312	modulator of DNA gyrase
BVG89_18820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVG89_18825	COG3164	Protein of unknown function
BVG89_18830	COG1530	ribonuclease E activity
BVG89_18840	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BVG89_18845	COG1792	Involved in formation and maintenance of cell shape
BVG89_18850	COG1077	Cell shape determining protein MreB Mrl
BVG89_18855	COG2200	EAL domain
BVG89_18855	COG2199	diguanylate cyclase activity
BVG89_18860	COG0604	alcohol dehydrogenase
BVG89_18865	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BVG89_18870	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BVG89_18875	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BVG89_18880	COG0511	ligase activity, forming carbon-carbon bonds
BVG89_18885	COG0439	Biotin carboxylase
BVG89_18890	COG3924	membrane
BVG89_18895	COG4145	pantothenate transmembrane transporter activity
BVG89_18900	COG2264	protein methyltransferase activity
BVG89_18925	COG1560	Kdo2-lipid A biosynthetic process
BVG89_18950	COG1380	Effector of murein hydrolase LrgA
BVG89_18955	COG0583	DNA-binding transcription factor activity
BVG89_18960	COG0025	NhaP-type Na H and K H
BVG89_18965	COG2252	PERMEase
BVG89_18975	COG0625	glutathione transferase activity
BVG89_18990	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_19010	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BVG89_19015	COG1064	alcohol dehydrogenase
BVG89_19020	COG0110	maltose O-acetyltransferase activity
BVG89_19025	COG2315	Protein conserved in bacteria
BVG89_19030	COG0432	Pfam Uncharacterised protein family UPF0047
BVG89_19035	COG1448	Aminotransferase
BVG89_19040	COG1522	sequence-specific DNA binding
BVG89_19050	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BVG89_19055	COG0305	Participates in initiation and elongation during chromosome replication
BVG89_19060	COG0604	alcohol dehydrogenase
BVG89_19070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BVG89_19090	COG0735	belongs to the Fur family
BVG89_19095	COG3237	CsbD-like
BVG89_19100	COG0534	Mate efflux family protein
BVG89_19105	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BVG89_19110	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BVG89_19115	COG2937	Belongs to the GPAT DAPAT family
BVG89_19120	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BVG89_19125	COG3161	chorismate lyase activity
BVG89_19130	COG0477	Major facilitator Superfamily
BVG89_19135	COG1609	Transcriptional regulator
BVG89_19150	COG4580	involved in the transport of maltose and maltodextrins
BVG89_19160	COG0366	Alpha amylase catalytic
BVG89_19165	COG2182	Extracellular solute-binding protein
BVG89_19170	COG1175	transmembrane transport
BVG89_19175	COG3833	ABC-type maltose transport systems, permease component
BVG89_19180	COG3223	Belongs to the PsiE family
BVG89_19190	COG0166	Belongs to the GPI family
BVG89_19200	COG0527	aspartate kinase activity
BVG89_19220	COG1283	sodium-dependent phosphate transmembrane transporter activity
BVG89_19225	COG3842	ATPase activity
BVG89_19240	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BVG89_19250	COG2188	Transcriptional regulator
BVG89_19255	COG0646	methionine synthase
BVG89_19255	COG1410	methionine synthase
BVG89_19260	COG1414	Transcriptional regulator
BVG89_19265	COG3265	gluconokinase activity
BVG89_19270	COG2610	gluconate transmembrane transporter activity
BVG89_19275	COG0129	dihydroxy-acid dehydratase activity
BVG89_19280	COG0800	Aldolase
BVG89_19285	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BVG89_19295	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BVG89_19300	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BVG89_19335	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BVG89_19340	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BVG89_19345	COG0009	L-threonylcarbamoyladenylate synthase
BVG89_19350	COG0551	DNA topoisomerase type I activity
BVG89_19355	COG2922	Belongs to the Smg family
BVG89_19360	COG0758	DNA mediated transformation
BVG89_19365	COG0242	peptide deformylase activity
BVG89_19370	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BVG89_19375	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BVG89_19375	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BVG89_19380	COG0569	domain protein
BVG89_19385	COG1970	mechanosensitive ion channel activity
BVG89_19390	COG3036	rescue of stalled ribosome
BVG89_19395	COG0789	Transcriptional regulator
BVG89_19405	COG0203	ribosomal protein L17
BVG89_19410	COG0202	RNA polymerase activity
BVG89_19415	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BVG89_19420	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BVG89_19425	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BVG89_19430	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BVG89_19435	COG0201	protein transport
BVG89_19445	COG1841	ribosomal large subunit assembly
BVG89_19450	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BVG89_19455	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BVG89_19460	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BVG89_19485	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BVG89_19500	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BVG89_19505	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BVG89_19515	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BVG89_19525	COG0089	rRNA binding
BVG89_19530	COG0088	Forms part of the polypeptide exit tunnel
BVG89_19535	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BVG89_19540	COG0051	transcription antitermination factor activity, RNA binding
BVG89_19555	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BVG89_19565	COG0049	tRNA binding
BVG89_19570	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BVG89_19575	COG2168	tRNA wobble position uridine thiolation
BVG89_19580	COG2923	Belongs to the DsrF TusC family
BVG89_19585	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BVG89_19590	COG2964	Protein conserved in bacteria
BVG89_19595	COG0545	Peptidyl-prolyl cis-trans isomerase
BVG89_19605	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BVG89_19610	COG1757	Na H antiporter
BVG89_19615	COG1609	Transcriptional regulator
BVG89_19620	COG1047	Peptidyl-prolyl cis-trans
BVG89_19625	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BVG89_19635	COG2249	NAD(P)H dehydrogenase (quinone) activity
BVG89_19640	COG0488	(ABC) transporter
BVG89_19645	COG2175	clavaminate synthase activity
BVG89_19650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVG89_19660	COG4521	taurine ABC transporter
BVG89_19675	COG0429	hydrolase of the alpha beta-hydrolase fold
BVG89_19680	COG3089	Belongs to the UPF0270 family
BVG89_19685	COG3954	Phosphoribulokinase
BVG89_19690	COG1765	OsmC-like protein
BVG89_19695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BVG89_19700	COG1289	transmembrane transporter activity
BVG89_19715	COG0433	COG0433 Predicted ATPase
BVG89_19725	COG3275	phosphorelay sensor kinase activity
BVG89_19730	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BVG89_19740	COG1447	Phosphotransferase system cellobiose-specific component IIA
BVG89_19745	COG1486	melibiose metabolic process
BVG89_19750	COG1609	Transcriptional regulator
BVG89_19755	COG0738	Major facilitator superfamily
BVG89_19760	COG0402	S-adenosylhomocysteine deaminase activity
BVG89_19765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BVG89_19770	COG2146	nitrite reductase [NAD(P)H] activity
BVG89_19775	COG2116	formate transmembrane transporter activity
BVG89_19780	COG1648	precorrin-2 dehydrogenase activity
BVG89_19780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BVG89_19785	COG0180	Tryptophanyl-tRNA synthetase
BVG89_19790	COG0546	phosphoglycolate phosphatase activity
BVG89_19810	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BVG89_19815	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BVG89_19820	COG4796	Type ii and iii secretion system protein
BVG89_19845	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BVG89_19850	COG0494	nUDIX hydrolase
BVG89_19860	COG1011	Hydrolase
BVG89_19865	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BVG89_19870	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BVG89_19895	COG0745	RESPONSE REGULATOR receiver
BVG89_19905	COG0484	heat shock protein binding
BVG89_19910	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BVG89_19915	COG2183	response to ionizing radiation
BVG89_19920	COG1918	ferrous iron import across plasma membrane
BVG89_19945	COG1040	competence protein
BVG89_19950	COG0316	Belongs to the HesB IscA family
BVG89_19950	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BVG89_19955	COG1640	4-alpha-glucanotransferase
BVG89_19960	COG0058	SHG alpha-glucan phosphorylase activity
BVG89_19970	COG2909	trisaccharide binding
BVG89_19975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BVG89_19980	COG0705	Rhomboid family
BVG89_19985	COG1349	DNA-binding transcription factor activity
BVG89_19990	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BVG89_19995	COG0058	SHG alpha-glucan phosphorylase activity
BVG89_20000	COG0297	glycogen (starch) synthase activity
BVG89_20005	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BVG89_20010	COG1523	belongs to the glycosyl hydrolase 13 family
BVG89_20015	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BVG89_20020	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BVG89_20025	COG2095	MarC family integral membrane protein
BVG89_20030	COG3265	gluconokinase activity
BVG89_20035	COG2610	gluconate transmembrane transporter activity
BVG89_20040	COG1609	Transcriptional regulator
BVG89_20045	COG1741	Belongs to the pirin family
BVG89_20050	COG1247	-acetyltransferase
BVG89_20055	COG3191	aminopeptidase activity
BVG89_20060	COG1082	Xylose isomerase domain protein TIM barrel
BVG89_20065	COG1082	Xylose isomerase domain protein TIM barrel
BVG89_20070	COG0673	inositol 2-dehydrogenase activity
BVG89_20075	COG3962	Belongs to the TPP enzyme family
BVG89_20080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVG89_20090	COG3718	enzyme involved in inositol metabolism
BVG89_20100	COG0477	Major facilitator Superfamily
BVG89_20100	COG2814	Major facilitator Superfamily
BVG89_20110	COG0390	transport system, permease component
BVG89_20115	COG4619	ABC transporter
BVG89_20145	COG3188	usher protein
BVG89_20170	COG2197	response regulator
BVG89_20180	COG0697	spore germination
BVG89_20200	COG0583	DNA-binding transcription factor activity
BVG89_20210	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_20220	COG0346	lactoylglutathione lyase activity
BVG89_20230	COG2081	HI0933 family
BVG89_20235	COG0306	phosphate transporter
BVG89_20250	COG0583	DNA-binding transcription factor activity
BVG89_20255	COG0589	response to stress
BVG89_20270	COG1129	ABC transporter
BVG89_20275	COG1172	Belongs to the binding-protein-dependent transport system permease family
BVG89_20280	COG1172	Belongs to the binding-protein-dependent transport system permease family
BVG89_20295	COG0742	ribosomal rna small subunit methyltransferase
BVG89_20300	COG0339	signal peptide processing
BVG89_20315	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BVG89_20320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVG89_20325	COG2318	DinB family
BVG89_20340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVG89_20350	COG0784	Response regulator, receiver
BVG89_20350	COG2205	protein histidine kinase activity
BVG89_20375	COG5441	Belongs to the UPF0261 family
BVG89_20380	COG5564	TIM-barrel signal transduction protein
BVG89_20385	COG3678	ATP-independent chaperone mediated protein folding
BVG89_20390	COG5001	Diguanylate cyclase
BVG89_20395	COG1024	Enoyl-CoA hydratase
BVG89_20400	COG1295	ribonuclease BN
BVG89_20405	COG0477	Major facilitator Superfamily
BVG89_20410	COG2134	cdp-diacylglycerol pyrophosphatase
BVG89_20415	COG2982	Protein involved in outer membrane biogenesis
BVG89_20420	COG2200	EAL domain
BVG89_20425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVG89_20435	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BVG89_20440	COG0583	DNA-binding transcription factor activity
BVG89_20460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BVG89_20465	COG0129	dihydroxy-acid dehydratase activity
BVG89_20470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BVG89_20475	COG3978	acetolactate synthase activity
BVG89_20500	COG3085	chromosome segregation
BVG89_20505	COG0583	DNA-binding transcription factor activity
BVG89_20545	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BVG89_20550	COG4206	TonB-dependent receptor
BVG89_20555	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BVG89_20570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVG89_20580	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BVG89_20580	COG0678	peroxiredoxin activity
BVG89_20585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVG89_20600	COG0165	Argininosuccinate lyase
BVG89_20605	COG0137	argininosuccinate synthase activity
BVG89_20610	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BVG89_20615	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BVG89_20625	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BVG89_20635	COG0527	aspartate kinase activity
BVG89_20635	COG0460	homoserine dehydrogenase
BVG89_20640	COG0626	cystathionine gamma-synthase activity
BVG89_20645	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
BVG89_20650	COG0254	rRNA binding
BVG89_20655	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BVG89_20660	COG1609	Transcriptional regulator
BVG89_20665	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BVG89_20670	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BVG89_20675	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BVG89_20680	COG1575	Belongs to the MenA family. Type 1 subfamily
BVG89_20685	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BVG89_20690	COG3074	FtsZ-dependent cytokinesis
BVG89_20705	COG1494	fructose-1,6-bisphosphatase
BVG89_20710	COG2814	Major facilitator Superfamily
BVG89_20725	COG3152	Membrane
BVG89_20735	COG0149	triose-phosphate isomerase activity
BVG89_20740	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BVG89_20745	COG0205	6-phosphofructokinase activity
BVG89_20750	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BVG89_20755	COG3678	ATP-independent chaperone mediated protein folding
BVG89_20760	COG0745	RESPONSE REGULATOR receiver
BVG89_20765	COG2205	protein histidine kinase activity
BVG89_20770	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BVG89_20785	COG1045	serine acetyltransferase
BVG89_20800	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BVG89_20805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BVG89_20810	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BVG89_20815	COG4942	peptidase
BVG89_20820	COG2861	carbohydrate metabolic process
BVG89_20825	COG1063	alcohol dehydrogenase
BVG89_20830	COG0156	8-amino-7-oxononanoate synthase activity
BVG89_20835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVG89_20840	COG0859	PFAM glycosyl transferase family 9
BVG89_20845	COG0859	PFAM glycosyl transferase family 9
BVG89_20850	COG0438	transferase activity, transferring glycosyl groups
BVG89_20855	COG3307	-O-antigen
BVG89_20860	COG1442	glycosyl transferase family 8
BVG89_20860	COG1216	Glycosyl transferase, family 2
BVG89_20875	COG0859	PFAM glycosyl transferase family 9
BVG89_20880	COG0438	transferase activity, transferring glycosyl groups
BVG89_20885	COG0438	transferase activity, transferring glycosyl groups
BVG89_20895	COG1519	Transferase
BVG89_20915	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BVG89_20920	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BVG89_20925	COG2003	Belongs to the UPF0758 family
BVG89_20930	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BVG89_20935	COG0756	dUTP diphosphatase activity
BVG89_20940	COG1309	transcriptional regulator
BVG89_20945	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BVG89_20950	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BVG89_20955	COG1561	YicC-like family, N-terminal region
BVG89_20965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BVG89_20975	COG2860	membrane
BVG89_20980	COG0194	GDP metabolic process
BVG89_20985	COG1758	RNA polymerase activity
BVG89_20990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BVG89_20995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BVG89_21000	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BVG89_21005	COG0786	glutamate:sodium symporter activity
BVG89_21010	COG2233	PERMEase
BVG89_21015	COG2982	Protein involved in outer membrane biogenesis
BVG89_21020	COG0456	acetyltransferase
BVG89_21025	COG1490	D-aminoacyl-tRNA deacylase activity
BVG89_21030	COG1295	ribonuclease BN
BVG89_21035	COG1011	Hydrolase
BVG89_21050	COG0174	glutamine synthetase
BVG89_21055	COG3852	Histidine kinase
BVG89_21065	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BVG89_21075	COG3078	GTPase activator activity
BVG89_21085	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BVG89_21090	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BVG89_21090	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BVG89_21095	COG0204	Acyl-transferase
BVG89_21100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BVG89_21105	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BVG89_21110	COG3084	Protein conserved in bacteria
BVG89_21115	COG0746	molybdenum cofactor guanylyltransferase activity
BVG89_21120	COG1763	Mo-molybdopterin cofactor biosynthetic process
BVG89_21145	COG2186	Transcriptional regulator
BVG89_21150	COG0477	Major facilitator Superfamily
BVG89_21155	COG1609	Transcriptional regulator
BVG89_21160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVG89_21165	COG1879	ABC-type sugar transport system periplasmic component
BVG89_21170	COG1172	Belongs to the binding-protein-dependent transport system permease family
BVG89_21175	COG1129	ABC transporter
BVG89_21180	COG1869	D-ribose catabolic process
BVG89_21185	COG3158	transport of potassium into the cell
BVG89_21190	COG0714	Associated with various cellular activities
BVG89_21195	COG2425	protein containing a von Willebrand factor type A (vWA) domain
BVG89_21200	COG2502	aspartate--ammonia ligase
BVG89_21205	COG1522	sequence-specific DNA binding
BVG89_21210	COG0716	FMN binding
BVG89_21215	COG0445	tRNA wobble uridine modification
BVG89_21220	COG0357	Ribosomal RNA small subunit methyltransferase G
BVG89_21225	COG3312	ion transport
BVG89_21240	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BVG89_21245	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BVG89_21250	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BVG89_21255	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BVG89_21260	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BVG89_21265	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BVG89_21270	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BVG89_21275	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BVG89_21280	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BVG89_21285	COG0573	inorganic phosphate transmembrane transporter activity
BVG89_21290	COG0581	inorganic phosphate transmembrane transporter activity
BVG89_21300	COG0704	Plays a role in the regulation of phosphate uptake
BVG89_21305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVG89_21310	COG0765	amino acid transport
BVG89_21315	COG0765	amino acid transport
BVG89_21320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BVG89_21325	COG0494	nUDIX hydrolase
BVG89_21330	COG2252	PERMEase
BVG89_21340	COG0431	NADPH-dependent FMN reductase
BVG89_21345	COG2091	lysine biosynthetic process via aminoadipic acid
BVG89_21355	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BVG89_21360	COG0706	membrane insertase activity
BVG89_21365	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BVG89_21370	COG0594	ribonuclease P activity
BVG89_21380	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BVG89_21385	COG0592	DNA-directed DNA polymerase activity
BVG89_21390	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BVG89_21395	COG0187	DNA topoisomerase II activity
BVG89_21400	COG0561	phosphatase activity
BVG89_21405	COG2423	ornithine cyclodeaminase activity
BVG89_21420	COG0823	Involved in the tonB-independent uptake of proteins
BVG89_21425	COG5645	(Lipo)protein
BVG89_21430	COG0071	Belongs to the small heat shock protein (HSP20) family
BVG89_21435	COG0071	Belongs to the small heat shock protein (HSP20) family
BVG89_21440	COG2985	domain, Protein
BVG89_21450	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BVG89_21455	COG3977	Valine--pyruvate aminotransferase
BVG89_21460	COG0366	Alpha amylase catalytic
BVG89_21465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BVG89_21470	COG2814	Major facilitator Superfamily
BVG89_21475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVG89_21485	COG1609	Transcriptional regulator
BVG89_21490	COG2885	chlorophyll binding
BVG89_21500	COG2818	Glycosylase
BVG89_21510	COG0752	glycyl-tRNA synthetase alpha subunit
BVG89_21515	COG0751	glycine-tRNA ligase activity
BVG89_21525	COG2213	PTS system mannitol-specific
BVG89_21525	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVG89_21530	COG0246	Mannitol dehydrogenase
BVG89_21535	COG3722	fumarate hydratase activity
BVG89_21545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVG89_21560	COG2258	MOSC domain
BVG89_21565	COG0840	transmembrane signaling receptor activity
BVG89_21570	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BVG89_21575	COG3383	formate dehydrogenase (NAD+) activity
BVG89_21575	COG0243	molybdopterin cofactor binding
BVG89_21580	COG0243	molybdopterin cofactor binding
BVG89_21580	COG3383	formate dehydrogenase (NAD+) activity
BVG89_21585	COG0437	4 iron, 4 sulfur cluster binding
BVG89_21590	COG2864	formate dehydrogenase
BVG89_21595	COG3058	Necessary for formate dehydrogenase activity
BVG89_21605	COG0625	glutathione transferase activity
BVG89_21610	COG1921	L-seryl-tRNASec selenium transferase activity
BVG89_21615	COG3276	selenocysteine insertion sequence binding
BVG89_21635	COG3274	enterobacterial common antigen metabolic process
BVG89_21650	COG0402	S-adenosylhomocysteine deaminase activity
BVG89_21655	COG0582	viral genome integration into host DNA
BVG89_21690	COG0582	viral genome integration into host DNA
BVG89_21695	COG5295	Hep Hag repeat protein
BVG89_21700	COG0740	serine-type endopeptidase activity
BVG89_21720	COG3501	Rhs element vgr protein
BVG89_21730	COG0582	viral genome integration into host DNA
BVG89_21770	COG0583	DNA-binding transcription factor activity
BVG89_21775	COG2807	transmembrane transport
BVG89_21785	COG0582	viral genome integration into host DNA
BVG89_21855	COG0745	RESPONSE REGULATOR receiver
BVG89_21860	COG2205	protein histidine kinase activity
BVG89_21905	COG1902	pentaerythritol trinitrate reductase activity
BVG89_21910	COG2814	Major facilitator Superfamily
BVG89_21950	COG1846	Transcriptional regulator
BVG89_21955	COG1764	response to oxidative stress
BVG89_21960	COG2194	sulfuric ester hydrolase activity
BVG89_21965	COG2197	response regulator
BVG89_21975	COG2271	Major facilitator Superfamily
BVG89_21995	COG0747	negative chemotaxis
BVG89_22000	COG0601	transmembrane transport
BVG89_22005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BVG89_22010	COG0444	Belongs to the ABC transporter superfamily
BVG89_22015	COG4608	Belongs to the ABC transporter superfamily
BVG89_22020	COG2194	sulfuric ester hydrolase activity
BVG89_22045	COG1215	transferase activity, transferring glycosyl groups
BVG89_22050	COG1215	transferase activity, transferring glycosyl groups
BVG89_22055	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BVG89_22060	COG0457	Tetratricopeptide repeat
BVG89_22060	COG3118	belongs to the thioredoxin family
BVG89_22065	COG2200	EAL domain
BVG89_22065	COG2199	diguanylate cyclase activity
BVG89_22070	COG1301	dicarboxylic acid transport
BVG89_22075	COG0612	Peptidase, M16
BVG89_22080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BVG89_22090	COG0248	Ppx GppA phosphatase
BVG89_22100	COG3118	belongs to the thioredoxin family
BVG89_22105	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BVG89_22110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BVG89_22120	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BVG89_22125	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BVG89_22130	COG1088	dTDP-glucose 4,6-dehydratase activity
BVG89_22135	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BVG89_22140	COG0456	acetyltransferase
BVG89_22145	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BVG89_22150	COG2244	polysaccharide biosynthetic process
BVG89_22155	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BVG89_22165	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BVG89_22170	COG1113	amino acid transport
BVG89_22195	COG3071	HemY protein
BVG89_22200	COG2959	enzyme of heme biosynthesis
BVG89_22210	COG0181	hydroxymethylbilane synthase activity
BVG89_22215	COG3072	Adenylate cyclase
BVG89_22220	COG1965	Belongs to the frataxin family
BVG89_22225	COG5567	small periplasmic lipoprotein
BVG89_22230	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BVG89_22235	COG3159	Protein conserved in bacteria
BVG89_22245	COG1011	Hydrolase
BVG89_22250	COG0210	DNA helicase
BVG89_22260	COG0598	Magnesium transport protein CorA
BVG89_22270	COG2050	protein possibly involved in aromatic compounds catabolism
BVG89_22275	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
BVG89_22280	COG0514	ATP-dependent DNA helicase (RecQ)
BVG89_22285	COG1280	lysine exporter protein (LysE YggA)
BVG89_22290	COG1280	lysine exporter protein (LysE YggA)
BVG89_22295	COG2267	carboxylic ester hydrolase activity
BVG89_22300	COG0561	phosphatase activity
BVG89_22305	COG0584	glycerophosphoryl diester phosphodiesterase
BVG89_22310	COG2271	Major facilitator Superfamily
BVG89_22320	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BVG89_22330	COG0247	lactate metabolic process
BVG89_22345	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BVG89_22350	COG0425	Belongs to the sulfur carrier protein TusA family
BVG89_22355	COG2217	Heavy metal translocating P-type atpase
BVG89_22370	COG3714	YhhN family
BVG89_22380	COG3776	membrane
BVG89_22385	COG0742	ribosomal rna small subunit methyltransferase
BVG89_22390	COG0552	protein localization to endoplasmic reticulum
BVG89_22390	COG0552	protein localization to endoplasmic reticulum
BVG89_22395	COG2884	Cell division ATP-binding protein ftsE
BVG89_22400	COG2177	Part of the ABC transporter FtsEX involved in
BVG89_22420	COG0456	acetyltransferase
BVG89_22430	COG0559	Belongs to the binding-protein-dependent transport system permease family
BVG89_22435	COG4177	L-phenylalanine transmembrane transporter activity
BVG89_22440	COG0411	ABC transporter
BVG89_22445	COG0410	ABC transporter
BVG89_22450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVG89_22455	COG1653	transport
BVG89_22460	COG1175	transmembrane transport
BVG89_22470	COG3842	ATPase activity
BVG89_22475	COG0584	glycerophosphoryl diester phosphodiesterase
BVG89_22495	COG0583	DNA-binding transcription factor activity
BVG89_22500	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BVG89_22505	COG0412	Dienelactone hydrolase
BVG89_22510	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BVG89_22520	COG0586	Pfam SNARE associated Golgi protein
BVG89_22525	COG1322	Protein conserved in bacteria
BVG89_22530	COG2226	methyltransferase
BVG89_22535	COG3165	ubiquinone biosynthetic process from chorismate
BVG89_22540	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BVG89_22545	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BVG89_22555	COG0805	protein transport
BVG89_22560	COG0084	hydrolase, TatD family'
BVG89_22590	COG0183	Belongs to the thiolase family
BVG89_22595	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVG89_22595	COG1024	Enoyl-CoA hydratase
BVG89_22605	COG0006	proline dipeptidase activity
BVG89_22610	COG1739	Uncharacterized protein family UPF0029
BVG89_22615	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BVG89_22650	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BVG89_22650	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BVG89_22655	COG1072	(Pantothenic acid kinase))
BVG89_22690	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BVG89_22695	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BVG89_22700	COG0250	Participates in transcription elongation, termination and antitermination
BVG89_22715	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BVG89_22725	COG0085	RNA polymerase activity
BVG89_22730	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BVG89_22745	COG5002	protein histidine kinase activity
BVG89_22745	COG3850	Histidine kinase
BVG89_22760	COG2022	thiamine diphosphate biosynthetic process
BVG89_22765	COG2104	thiamine diphosphate biosynthetic process
BVG89_22770	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BVG89_22775	COG0352	thiamine-phosphate diphosphorylase activity
BVG89_22780	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BVG89_22785	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BVG89_22790	COG2816	NAD+ diphosphatase activity
BVG89_22795	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BVG89_22800	COG1515	deoxyribonuclease V activity
BVG89_22805	COG3068	Protein conserved in bacteria
BVG89_22820	COG0151	Belongs to the GarS family
BVG89_22825	COG0138	bifunctional purine biosynthesis protein purh
BVG89_22860	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BVG89_22865	COG3162	membrane
BVG89_22870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BVG89_22875	COG1301	dicarboxylic acid transport
BVG89_22880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVG89_22880	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BVG89_22885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVG89_22885	COG2226	methyltransferase
BVG89_22885	COG3433	isochorismatase activity
BVG89_22890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVG89_22895	COG1629	transport
BVG89_22895	COG4774	siderophore transport
BVG89_22900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVG89_22905	COG3391	amine dehydrogenase activity
BVG89_22910	COG4771	TonB-dependent receptor
BVG89_22915	COG2382	esterase
BVG89_22925	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BVG89_22925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVG89_22935	COG1169	isochorismate synthase
BVG89_22940	COG1021	2,3-dihydroxybenzoate-AMP ligase
BVG89_22945	COG1535	isochorismatase
BVG89_22945	COG3433	isochorismatase activity
BVG89_22955	COG3647	Membrane
BVG89_22985	COG3188	usher protein
BVG89_22990	COG3121	Chaperone
BVG89_22995	COG3539	Fimbrial protein
BVG89_23010	COG3539	Fimbrial protein
BVG89_23030	COG1309	transcriptional regulator
BVG89_23035	COG4232	protein-disulfide reductase activity
BVG89_23045	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BVG89_23060	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BVG89_23070	COG0840	transmembrane signaling receptor activity
BVG89_23080	COG1509	lysine 2,3-aminomutase activity
BVG89_23085	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BVG89_23090	COG5510	response to toxic substance
BVG89_23095	COG5510	response to toxic substance
BVG89_23110	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BVG89_23115	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BVG89_23120	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BVG89_23125	COG1053	succinate dehydrogenase
BVG89_23130	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BVG89_23135	COG1511	domain protein
BVG89_23135	COG3264	Mechanosensitive ion channel
BVG89_23145	COG1162	GTPase activity
BVG89_23150	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BVG89_23170	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BVG89_23175	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BVG89_23175	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BVG89_23180	COG0802	atpase or kinase
BVG89_23190	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BVG89_23195	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BVG89_23205	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BVG89_23210	COG0330	HflC and HflK could
BVG89_23215	COG0330	HflC and HflK could
BVG89_23220	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BVG89_23225	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BVG89_23230	COG1959	2 iron, 2 sulfur cluster binding
BVG89_23235	COG0557	exoribonuclease II activity
BVG89_23240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BVG89_23245	COG1960	acyl-CoA dehydrogenase activity
BVG89_23250	COG3766	membrane
BVG89_23260	COG3650	response to hydrogen peroxide
BVG89_23265	COG1073	alpha beta
BVG89_23280	COG0360	Binds together with S18 to 16S ribosomal RNA
BVG89_23295	COG0359	binds to the 23S rRNA
BVG89_23305	COG3061	Opacity-associated protein A
BVG89_23310	COG0545	Peptidyl-prolyl cis-trans isomerase
BVG89_23320	COG0737	Belongs to the 5'-nucleotidase family
BVG89_23330	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BVG89_23340	COG1253	flavin adenine dinucleotide binding
BVG89_23345	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BVG89_23350	COG0729	surface antigen
BVG89_23355	COG2911	Protein conserved in bacteria
BVG89_23360	COG2105	PFAM AIG2 family protein
BVG89_23365	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BVG89_23375	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BVG89_23380	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BVG89_23395	COG1438	arginine binding
BVG89_23400	COG0039	L-malate dehydrogenase activity
BVG89_23405	COG3423	Transcriptional regulator
BVG89_23415	COG0142	geranyltranstransferase activity
BVG89_23420	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BVG89_23425	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BVG89_23430	COG0697	spore germination
BVG89_23435	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BVG89_23440	COG0642	Histidine kinase
BVG89_23445	COG0745	RESPONSE REGULATOR receiver
BVG89_23450	COG2027	D-alanyl-D-alanine carboxypeptidase
BVG89_23455	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BVG89_23460	COG1534	Rna-binding protein
BVG89_23465	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BVG89_23470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BVG89_23475	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BVG89_23480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BVG89_23485	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BVG89_23500	COG0779	Required for maturation of 30S ribosomal subunits
BVG89_23505	COG0195	Participates in both transcription termination and antitermination
BVG89_23510	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BVG89_23515	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BVG89_23520	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BVG89_23525	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BVG89_23530	COG1185	polyribonucleotide nucleotidyltransferase activity
BVG89_23540	COG0513	Belongs to the DEAD box helicase family
BVG89_23545	COG2391	methyltransferase activity
BVG89_23550	COG0425	Belongs to the sulfur carrier protein TusA family
BVG89_23555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVG89_23590	COG3153	acetyltransferase
BVG89_23595	COG2827	Endonuclease containing a URI domain
BVG89_23600	COG0531	amino acid
BVG89_23605	COG1982	Orn Lys Arg decarboxylase major
BVG89_23615	COG3787	Belongs to the UPF0306 family
BVG89_23620	COG0702	epimerase
BVG89_23625	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BVG89_23635	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BVG89_23640	COG3454	Phosphonate metabolism
BVG89_23645	COG4778	phosphonate C-P lyase system protein PhnL
BVG89_23650	COG4107	phosphonate C-P lyase system protein PhnK
BVG89_23655	COG3627	carbon phosphorus lyase activity
BVG89_23660	COG3626	phosphonate metabolism
BVG89_23665	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
BVG89_23670	COG3624	Phosphonate C-P lyase system protein PhnG
BVG89_23675	COG2188	Transcriptional regulator
BVG89_23680	COG0701	Predicted permease
BVG89_23710	COG0602	queuosine metabolic process
BVG89_23725	COG0583	DNA-binding transcription factor activity
BVG89_23730	COG2249	NAD(P)H dehydrogenase (quinone) activity
BVG89_23735	COG0366	Alpha amylase catalytic
BVG89_23740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVG89_23740	COG1263	PTS System
BVG89_23755	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BVG89_23775	COG0540	Belongs to the ATCase OTCase family
BVG89_23785	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BVG89_23790	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BVG89_23800	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BVG89_23805	COG0456	acetyltransferase
BVG89_23815	COG2927	DNA polymerase III (CHI subunit)
BVG89_23820	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BVG89_23825	COG0795	lipopolysaccharide-transporting ATPase activity
BVG89_23830	COG0795	lipopolysaccharide-transporting ATPase activity
BVG89_23855	COG0738	Major facilitator superfamily
BVG89_23875	COG0582	viral genome integration into host DNA
BVG89_23955	COG2815	serine threonine protein kinase
BVG89_23955	COG0515	serine threonine protein kinase
BVG89_23975	COG3550	peptidyl-serine autophosphorylation
BVG89_23980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVG89_23980	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BVG89_23995	COG1401	restriction endodeoxyribonuclease activity
BVG89_24045	COG2723	6-phospho-beta-galactosidase activity
BVG89_24050	COG1263	PTS System
BVG89_24050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVG89_24055	COG1609	Transcriptional regulator
BVG89_24065	COG1132	(ABC) transporter
BVG89_24070	COG1132	(ABC) transporter
BVG89_24095	COG0523	cobalamin synthesis protein
BVG89_24100	COG2879	small protein
BVG89_24105	COG1966	Carbon starvation protein
BVG89_24135	COG1116	anion transmembrane transporter activity
BVG89_24145	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BVG89_24155	COG0174	glutamine synthetase
BVG89_24175	COG0583	DNA-binding transcription factor activity
BVG89_24180	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BVG89_24195	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVG89_24200	COG2610	gluconate transmembrane transporter activity
BVG89_24205	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_24215	COG2207	Transcriptional regulator
BVG89_24225	COG2207	Transcriptional regulator
BVG89_24225	COG3708	Transcriptional regulator
BVG89_24230	COG1376	ErfK ybiS ycfS ynhG family protein
BVG89_24260	COG0811	peptide transport
BVG89_24295	COG1454	alcohol dehydrogenase
BVG89_24305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVG89_24315	COG2267	carboxylic ester hydrolase activity
BVG89_24345	COG1113	amino acid transport
BVG89_24370	COG1846	Transcriptional regulator
BVG89_24380	COG0179	Fumarylacetoacetate (FAA) hydrolase
BVG89_24385	COG1012	belongs to the aldehyde dehydrogenase family
BVG89_24400	COG3971	2-oxopent-4-enoate hydratase activity
BVG89_24420	COG2368	4-hydroxyphenylacetate
BVG89_24425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVG89_24430	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BVG89_24440	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_24445	COG0179	Fumarylacetoacetate (FAA) hydrolase
BVG89_24450	COG4948	Mandelate Racemase Muconate Lactonizing
BVG89_24455	COG3618	amidohydrolase
BVG89_24460	COG1028	Short-chain dehydrogenase reductase Sdr
BVG89_24465	COG3254	rhamnose metabolic process
BVG89_24470	COG0738	Major facilitator superfamily
BVG89_24490	COG1309	transcriptional regulator
BVG89_24495	COG3706	GGDEF domain
BVG89_24525	COG0667	Aldo Keto reductase
BVG89_24530	COG2813	Specifically methylates the guanine in position
BVG89_24535	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
BVG89_24545	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BVG89_24550	COG2823	Periplasmic or secreted lipoprotein
BVG89_24555	COG5487	UPF0391 membrane protein
BVG89_24560	COG3237	CsbD-like
BVG89_24565	COG4667	esterase of the alpha-beta hydrolase superfamily
BVG89_24570	COG0084	hydrolase, TatD family'
BVG89_24575	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BVG89_24580	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BVG89_24585	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BVG89_24590	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BVG89_24595	COG0813	purine-nucleoside phosphorylase activity
BVG89_24600	COG3726	membrane protein affecting hemolysin expression
BVG89_24605	COG0560	Phosphoserine phosphatase
BVG89_24625	COG0604	alcohol dehydrogenase
BVG89_24635	COG2130	NADP-dependent
BVG89_24650	COG0488	(ABC) transporter
BVG89_24655	COG2885	chlorophyll binding
BVG89_24660	COG2199	diguanylate cyclase activity
BVG89_24670	COG0741	lytic transglycosylase activity
BVG89_24675	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
BVG89_24680	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BVG89_24685	COG0406	alpha-ribazole phosphatase activity
BVG89_24690	COG2207	Transcriptional regulator
BVG89_24690	COG3708	Transcriptional regulator
BVG89_24695	COG3045	CreA protein
BVG89_24700	COG0745	RESPONSE REGULATOR receiver