locus-tag	class	description
AD867_00010	COG0527	aspartate kinase activity
AD867_00010	COG0460	homoserine dehydrogenase
AD867_00020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AD867_00050	COG0521	Mo-molybdopterin cofactor biosynthetic process
AD867_00055	COG1584	GPR1 FUN34 yaaH family protein
AD867_00060	COG4735	regulation of single-species biofilm formation
AD867_00090	COG0583	DNA-binding transcription factor activity
AD867_00100	COG1662	PFAM IS1 transposase
AD867_00115	COG0196	riboflavin kinase activity
AD867_00130	COG1047	Peptidyl-prolyl cis-trans
AD867_00160	COG0505	Belongs to the CarA family
AD867_00165	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AD867_00230	COG2271	Major facilitator Superfamily
AD867_00250	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AD867_00275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AD867_00285	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AD867_00290	COG0564	pseudouridine synthase activity
AD867_00300	COG0417	DNA replication proofreading
AD867_00305	COG0235	Class ii aldolase
AD867_00320	COG4977	sequence-specific DNA binding
AD867_00325	COG0586	Pfam SNARE associated Golgi protein
AD867_00335	COG1178	ABC-type Fe3 transport system permease component
AD867_00340	COG4143	(ABC) transporter
AD867_00355	COG2814	Major facilitator Superfamily
AD867_00385	COG0583	DNA-binding transcription factor activity
AD867_00390	COG0028	Belongs to the TPP enzyme family
AD867_00395	COG0440	acetolactate synthase activity
AD867_00405	COG1609	Transcriptional regulator
AD867_00410	COG3677	Transposase
AD867_00415	COG1662	PFAM IS1 transposase
AD867_00430	COG3116	cell division
AD867_00435	COG0768	penicillin binding
AD867_00445	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AD867_00460	COG0772	Belongs to the SEDS family
AD867_00480	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AD867_00485	COG0849	cell division
AD867_00490	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AD867_00510	COG0494	nUDIX hydrolase
AD867_00540	COG1459	type II secretion system
AD867_00545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AD867_00550	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AD867_00555	COG4969	Belongs to the N-Me-Phe pilin family
AD867_00565	COG0157	Belongs to the NadC ModD family
AD867_00570	COG3023	N-Acetylmuramoyl-L-alanine amidase
AD867_00575	COG3725	Membrane protein required for beta-lactamase induction
AD867_00585	COG2186	Transcriptional regulator
AD867_00590	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AD867_00595	COG0508	dehydrogenase complex catalyzes the overall conversion of
AD867_00600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AD867_00610	COG1049	propionate catabolic process, 2-methylcitrate cycle
AD867_00635	COG2132	Multicopper oxidase
AD867_00640	COG4993	Dehydrogenase
AD867_00645	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AD867_00650	COG0288	reversible hydration of carbon dioxide
AD867_00655	COG1131	(ABC) transporter
AD867_00660	COG0842	Transport permease protein
AD867_00665	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AD867_00670	COG0726	polysaccharide deacetylase
AD867_00680	COG5464	transposase or invertase
AD867_00695	COG3539	Fimbrial protein
AD867_00700	COG3677	Transposase
AD867_00710	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AD867_00715	COG0617	tRNA 3'-terminal CCA addition
AD867_00725	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AD867_00735	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AD867_00740	COG1643	Atp-dependent helicase
AD867_00750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AD867_00755	COG4774	siderophore transport
AD867_00760	COG1120	ATPase activity
AD867_00765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AD867_00770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AD867_00790	COG2860	membrane
AD867_00810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AD867_00835	COG0024	Methionine aminopeptidase
AD867_00865	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AD867_00870	COG0575	Belongs to the CDS family
AD867_00875	COG0750	zinc metalloprotease
AD867_00885	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AD867_00890	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AD867_00915	COG0587	DNA-directed DNA polymerase activity
AD867_00930	COG0346	lactoylglutathione lyase activity
AD867_00940	COG4568	rho-dependent transcription termination
AD867_00950	COG4681	YaeQ
AD867_00955	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AD867_00960	COG3015	lipoprotein NlpE involved in copper resistance
AD867_00965	COG0791	NLP P60 protein
AD867_00975	COG1720	tRNA m6t6A37 methyltransferase activity
AD867_00985	COG1464	Belongs to the NlpA lipoprotein family
AD867_00990	COG2011	ABC-type metal ion transport system permease component
AD867_00995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AD867_01000	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AD867_01035	COG0656	L-ascorbic acid biosynthetic process
AD867_01040	COG3385	transposase activity
AD867_01045	COG0583	DNA-binding transcription factor activity
AD867_01055	COG2226	methyltransferase
AD867_01060	COG0741	lytic transglycosylase activity
AD867_01060	COG1388	LysM domain
AD867_01070	COG2226	methyltransferase
AD867_01080	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AD867_01230	COG1785	Belongs to the alkaline phosphatase family
AD867_01245	COG1181	Belongs to the D-alanine--D-alanine ligase family
AD867_01265	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AD867_01275	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AD867_01280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AD867_01285	COG3468	outer membrane autotransporter barrel domain protein
AD867_01290	COG2801	Transposase and inactivated derivatives
AD867_01310	COG3468	outer membrane autotransporter barrel domain protein
AD867_01320	COG2963	transposase activity
AD867_01325	COG3677	Transposase
AD867_01330	COG1662	PFAM IS1 transposase
AD867_01340	COG0113	porphobilinogen synthase activity
AD867_01345	COG2175	clavaminate synthase activity
AD867_01350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AD867_01360	COG4521	taurine ABC transporter
AD867_01385	COG1556	Lactate utilization protein
AD867_01390	COG1139	Iron-sulfur cluster binding protein
AD867_01395	COG0247	lactate metabolic process
AD867_01400	COG1662	PFAM IS1 transposase
AD867_01415	COG3501	Rhs element vgr protein
AD867_01435	COG3209	COG3209 Rhs family protein
AD867_01445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AD867_01455	COG1960	acyl-CoA dehydrogenase activity
AD867_01465	COG0121	glutamine amidotransferase
AD867_01470	COG3034	peptidoglycan biosynthetic process
AD867_01475	COG0791	NLP P60 protein
AD867_01480	COG1943	Transposase
AD867_01500	COG2161	toxin-antitoxin pair type II binding
AD867_01510	COG0454	-acetyltransferase
AD867_01525	COG2195	Cleaves the N-terminal amino acid of tripeptides
AD867_01545	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AD867_01550	COG3677	Transposase
AD867_01555	COG1662	PFAM IS1 transposase
AD867_01575	COG0582	viral genome integration into host DNA
AD867_01630	COG0582	viral genome integration into host DNA
AD867_01635	COG2246	polysaccharide biosynthetic process
AD867_01680	COG0582	viral genome integration into host DNA
AD867_01720	COG3706	GGDEF domain
AD867_01725	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AD867_01750	COG4126	flavin adenine dinucleotide binding
AD867_01775	COG1940	carbohydrate kinase activity
AD867_01780	COG2814	Major facilitator Superfamily
AD867_01785	COG0419	ATPase involved in DNA repair
AD867_01790	COG0420	3'-5' exonuclease activity
AD867_01800	COG5002	protein histidine kinase activity
AD867_01805	COG1114	Component of the transport system for branched-chain amino acids
AD867_01810	COG1113	amino acid transport
AD867_01815	COG0366	Alpha amylase catalytic
AD867_01835	COG1862	Preprotein translocase
AD867_01840	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AD867_01845	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AD867_01850	COG1403	HNH endonuclease
AD867_01860	COG3248	Nucleoside-binding outer membrane protein
AD867_01865	COG4238	major outer membrane lipoprotein
AD867_01875	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AD867_01875	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AD867_01890	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AD867_01895	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AD867_01900	COG0667	Aldo Keto reductase
AD867_01910	COG0142	geranyltranstransferase activity
AD867_01925	COG0693	protein deglycase activity
AD867_01930	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AD867_01950	COG3677	Transposase
AD867_01955	COG1662	PFAM IS1 transposase
AD867_01980	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AD867_01985	COG1845	cytochrome c oxidase, subunit III
AD867_02005	COG3436	PFAM IS66 Orf2 family protein
AD867_02015	COG2223	nitrite transmembrane transporter activity
AD867_02020	COG3056	Lipoprotein
AD867_02025	COG0271	Belongs to the BolA IbaG family
AD867_02055	COG0776	regulation of translation
AD867_02060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AD867_02065	COG1555	photosystem II stabilization
AD867_02070	COG0824	Thioesterase
AD867_02080	COG4533	DNA binding
AD867_02090	COG1522	sequence-specific DNA binding
AD867_02095	COG1132	(ABC) transporter
AD867_02100	COG1132	(ABC) transporter
AD867_02105	COG0347	Belongs to the P(II) protein family
AD867_02110	COG0004	ammonium transporteR
AD867_02115	COG1946	Acyl-CoA thioesterase
AD867_02120	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AD867_02125	COG3385	transposase activity
AD867_02130	COG3695	enzyme binding
AD867_02135	COG5507	3-demethylubiquinone-9 3-methyltransferase
AD867_02140	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AD867_02170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AD867_02175	COG1309	transcriptional regulator
AD867_02180	COG3264	Mechanosensitive ion channel
AD867_02180	COG1196	nuclear chromosome segregation
AD867_02195	COG3923	Primosomal replication protein n
AD867_02200	COG2832	Protein of unknown function (DUF454)
AD867_02210	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AD867_02245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AD867_02250	COG4651	solute:proton antiporter activity
AD867_02250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AD867_02255	COG2223	nitrite transmembrane transporter activity
AD867_02260	COG0737	Belongs to the 5'-nucleotidase family
AD867_02265	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AD867_02270	COG3735	TraB family
AD867_02275	COG3093	addiction module antidote protein HigA
AD867_02280	COG2217	Heavy metal translocating P-type atpase
AD867_02290	COG0531	amino acid
AD867_02295	COG0789	Transcriptional regulator
AD867_02300	COG1585	Membrane protein implicated in regulation of membrane protease activity
AD867_02305	COG0330	HflC and HflK could
AD867_02310	COG4619	ABC transporter
AD867_02315	COG0390	transport system, permease component
AD867_02320	COG3118	belongs to the thioredoxin family
AD867_02325	COG0300	oxidoreductase activity
AD867_02335	COG4181	ATPase activity
AD867_02340	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AD867_02350	COG0583	DNA-binding transcription factor activity
AD867_02355	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AD867_02360	COG1414	Transcriptional regulator
AD867_02365	COG3960	tartronate-semialdehyde synthase activity
AD867_02370	COG3622	Belongs to the hyi family
AD867_02380	COG3677	Transposase
AD867_02390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AD867_02400	COG0549	Belongs to the carbamate kinase family
AD867_02405	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AD867_02410	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AD867_02420	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AD867_02430	COG1988	membrane-bound metal-dependent
AD867_02435	COG2501	S4 domain
AD867_02445	COG3539	Fimbrial protein
AD867_02450	COG3121	Chaperone
AD867_02455	COG3188	usher protein
AD867_02460	COG1662	PFAM IS1 transposase
AD867_02465	COG3677	Transposase
AD867_02480	COG2207	Transcriptional regulator
AD867_02495	COG1215	transferase activity, transferring glycosyl groups
AD867_02500	COG5002	protein histidine kinase activity
AD867_02505	COG0745	RESPONSE REGULATOR receiver
AD867_02510	COG1538	Outer membrane efflux protein
AD867_02515	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AD867_02520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AD867_02560	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AD867_02565	COG1113	amino acid transport
AD867_02570	COG0668	transmembrane transport
AD867_02575	COG0778	Nitroreductase
AD867_02580	COG2315	Protein conserved in bacteria
AD867_02595	COG2963	transposase activity
AD867_02625	COG2801	Transposase and inactivated derivatives
AD867_02640	COG2977	Belongs to the P-Pant transferase superfamily
AD867_02645	COG4771	TonB-dependent receptor
AD867_02650	COG2382	esterase
AD867_02655	COG3251	PFAM MbtH domain protein
AD867_02665	COG3677	Transposase
AD867_02670	COG1662	PFAM IS1 transposase
AD867_02675	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AD867_02680	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AD867_02685	COG1120	ATPase activity
AD867_02690	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AD867_02695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AD867_02705	COG4592	Periplasmic binding protein
AD867_02715	COG1021	2,3-dihydroxybenzoate-AMP ligase
AD867_02720	COG3433	isochorismatase activity
AD867_02720	COG1535	isochorismatase
AD867_02725	COG1028	Short-chain dehydrogenase reductase Sdr
AD867_02735	COG1966	Carbon starvation protein
AD867_02740	COG2879	small protein
AD867_02745	COG0371	Dehydrogenase
AD867_02750	COG0436	Aminotransferase
AD867_02755	COG1475	DNA binding
AD867_02775	COG3969	phosphoadenosine phosphosulfate
AD867_02780	COG3969	phosphoadenosine phosphosulfate
AD867_02785	COG2963	transposase activity
AD867_02790	COG2801	Transposase and inactivated derivatives
AD867_02795	COG0583	DNA-binding transcription factor activity
AD867_02800	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AD867_02805	COG0450	alkyl hydroperoxide reductase
AD867_02810	COG3634	alkyl hydroperoxide reductase activity
AD867_02820	COG1063	alcohol dehydrogenase
AD867_02830	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AD867_02835	COG3719	Belongs to the RNase T2 family
AD867_02855	COG3051	citrate lyase alpha subunit
AD867_02860	COG2301	Belongs to the HpcH HpaI aldolase family
AD867_02870	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AD867_02875	COG1662	PFAM IS1 transposase
AD867_02880	COG0582	viral genome integration into host DNA
AD867_02885	COG0561	phosphatase activity
AD867_02895	COG4149	molybdate abc transporter
AD867_02900	COG0725	ABC transporter, periplasmic molybdate-binding protein
AD867_02910	COG2005	Transcriptional regulator
AD867_02910	COG3585	molybdate ion transport
AD867_02915	COG1119	ATPase activity
AD867_02920	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AD867_02925	COG1085	galactose-1-phosphate uridylyltransferase
AD867_02935	COG2017	converts alpha-aldose to the beta-anomer
AD867_02945	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AD867_02965	COG3201	nicotinamide mononucleotide transporter
AD867_03000	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AD867_03005	COG2885	chlorophyll binding
AD867_03015	COG3064	Membrane
AD867_03020	COG0848	biopolymer transport protein
AD867_03025	COG0811	peptide transport
AD867_03030	COG0824	Thioesterase
AD867_03035	COG3790	cyd operon protein YbgE
AD867_03040	COG4890	Cyd operon protein YbgT
AD867_03045	COG1294	oxidase, subunit
AD867_03050	COG1271	oxidase subunit
AD867_03060	COG0383	alpha-mannosidase activity
AD867_03065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AD867_03065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AD867_03065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AD867_03070	COG2188	Transcriptional regulator
AD867_03075	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AD867_03085	COG0508	dehydrogenase complex catalyzes the overall conversion of
AD867_03090	COG0567	Dehydrogenase, E1 component
AD867_03100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AD867_03105	COG1053	succinate dehydrogenase
AD867_03110	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AD867_03115	COG2009	succinate dehydrogenase
AD867_03125	COG0372	Belongs to the citrate synthase family
AD867_03130	COG3539	Fimbrial protein
AD867_03135	COG3188	usher protein
AD867_03140	COG3121	Chaperone
AD867_03145	COG3539	Fimbrial protein
AD867_03155	COG3180	Ammonia monooxygenase
AD867_03175	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AD867_03180	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AD867_03190	COG0415	Belongs to the DNA photolyase family
AD867_03195	COG3272	Protein of unknown function (DUF1722)
AD867_03210	COG3209	COG3209 Rhs family protein
AD867_03220	COG1662	PFAM IS1 transposase
AD867_03225	COG3677	Transposase
AD867_03275	COG0531	amino acid
AD867_03280	COG0033	Phosphoglucomutase
AD867_03285	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AD867_03290	COG0596	Alpha beta hydrolase
AD867_03300	COG0716	FMN binding
AD867_03315	COG0735	belongs to the Fur family
AD867_03335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AD867_03335	COG2190	(PTS) system
AD867_03335	COG1263	PTS System
AD867_03345	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AD867_03350	COG1846	Transcriptional regulator
AD867_03350	COG1940	carbohydrate kinase activity
AD867_03355	COG0647	UMP catabolic process
AD867_03360	COG0647	UMP catabolic process
AD867_03365	COG0367	asparagine synthase
AD867_03405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AD867_03415	COG1702	phosphate starvation-inducible protein PhoH
AD867_03425	COG4535	Mg2 and Co2 transporter CorC
AD867_03435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AD867_03440	COG0765	amino acid transport
AD867_03445	COG0765	amino acid transport
AD867_03450	COG1126	abc transporter atp-binding protein
AD867_03465	COG2214	Heat shock protein DnaJ domain protein
AD867_03475	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AD867_03480	COG2214	Heat shock protein DnaJ domain protein
AD867_03490	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AD867_03495	COG2888	peptidyl-tyrosine sulfation
AD867_03510	COG1466	dna polymerase III delta subunit
AD867_03520	COG0406	alpha-ribazole phosphatase activity
AD867_03525	COG0799	negative regulation of ribosome biogenesis
AD867_03535	COG0768	penicillin binding
AD867_03540	COG0772	Belongs to the SEDS family
AD867_03545	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AD867_03550	COG1686	Belongs to the peptidase S11 family
AD867_03570	COG0583	DNA-binding transcription factor activity
AD867_03580	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AD867_03585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AD867_03595	COG1278	Cold shock
AD867_03605	COG3069	C4-dicarboxylate transmembrane transporter activity
AD867_03620	COG2801	Transposase and inactivated derivatives
AD867_03665	COG1783	phage Terminase large subunit
AD867_03680	COG2963	transposase activity
AD867_03770	COG1484	DNA-dependent DNA replication
AD867_03775	COG0305	Participates in initiation and elongation during chromosome replication
AD867_03825	COG3772	lysozyme
AD867_03980	COG1881	PFAM PEBP family protein
AD867_03985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AD867_04000	COG2226	methyltransferase
AD867_04005	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AD867_04015	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AD867_04030	COG0521	Mo-molybdopterin cofactor biosynthetic process
AD867_04040	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AD867_04045	COG0314	molybdopterin synthase activity
AD867_04050	COG0670	Belongs to the BI1 family
AD867_04055	COG0670	Belongs to the BI1 family
AD867_04060	COG0392	lysyltransferase activity
AD867_04070	COG3568	Endonuclease Exonuclease Phosphatase
AD867_04080	COG0842	Transport permease protein
AD867_04085	COG0842	Transport permease protein
AD867_04090	COG1131	(ABC) transporter
AD867_04100	COG1309	transcriptional regulator
AD867_04105	COG0513	Belongs to the DEAD box helicase family
AD867_04125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AD867_04130	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AD867_04140	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AD867_04155	COG3385	transposase activity
AD867_04160	COG4774	siderophore transport
AD867_04175	COG0668	transmembrane transport
AD867_04185	COG1126	abc transporter atp-binding protein
AD867_04190	COG0765	amino acid transport
AD867_04195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AD867_04210	COG5006	permease, DMT superfamily
AD867_04215	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AD867_04220	COG2194	sulfuric ester hydrolase activity
AD867_04230	COG1321	iron dependent repressor
AD867_04235	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AD867_04240	COG1376	ErfK ybiS ycfS ynhG family protein
AD867_04245	COG0488	(ABC) transporter
AD867_04255	COG0561	phosphatase activity
AD867_04265	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AD867_04270	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AD867_04275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AD867_04280	COG0303	'Molybdopterin
AD867_04285	COG1446	asparaginase
AD867_04310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AD867_04315	COG2200	EAL domain
AD867_04320	COG2200	EAL domain
AD867_04325	COG2199	diguanylate cyclase activity
AD867_04340	COG2133	pyrroloquinoline quinone binding
AD867_04345	COG2133	pyrroloquinoline quinone binding
AD867_04350	COG0625	glutathione transferase activity
AD867_04355	COG1686	Belongs to the peptidase S11 family
AD867_04370	COG1686	Belongs to the peptidase S11 family
AD867_04375	COG1349	DNA-binding transcription factor activity
AD867_04380	COG0671	phosphoesterase, PA-phosphatase related
AD867_04385	COG2814	Major facilitator Superfamily
AD867_04395	COG0561	phosphatase activity
AD867_04400	COG0738	Major facilitator superfamily
AD867_04405	COG3226	Transcriptional regulator
AD867_04420	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AD867_04430	COG0778	Nitroreductase
AD867_04450	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AD867_04455	COG3842	ATPase activity
AD867_04460	COG1176	ABC-type spermidine putrescine transport system, permease component I
AD867_04465	COG1177	transmembrane transport
AD867_04480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AD867_04485	COG4160	amino acid transport
AD867_04490	COG4215	(ABC) transporter
AD867_04495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AD867_04500	COG1126	abc transporter atp-binding protein
AD867_04530	COG3023	N-Acetylmuramoyl-L-alanine amidase
AD867_04535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AD867_04540	COG0702	epimerase
AD867_04545	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AD867_04550	COG0028	Belongs to the TPP enzyme family
AD867_04555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AD867_04565	COG2431	L-lysine efflux transmembrane transporter activity
AD867_04575	COG2963	transposase activity
AD867_04580	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AD867_04590	COG3677	Transposase
AD867_04600	COG3593	DNA synthesis involved in DNA repair
AD867_04605	COG2990	Protein conserved in bacteria
AD867_04610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AD867_04620	COG1278	Cold shock
AD867_04630	COG0542	response to heat
AD867_04650	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AD867_04655	COG4988	ABC transporter
AD867_04660	COG0492	ferredoxin-NADP+ reductase activity
AD867_04665	COG1522	sequence-specific DNA binding
AD867_04680	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AD867_04695	COG0243	molybdopterin cofactor binding
AD867_04700	COG0437	4 iron, 4 sulfur cluster binding
AD867_04705	COG3302	dmso reductase anchor subunit
AD867_04710	COG1335	isochorismatase
AD867_04725	COG3436	PFAM IS66 Orf2 family protein
AD867_04730	COG4372	Transposase
AD867_04755	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AD867_04790	COG1396	sequence-specific DNA binding
AD867_04810	COG2963	transposase activity
AD867_04815	COG3646	Phage regulatory protein
AD867_04875	COG2828	Protein conserved in bacteria
AD867_04880	COG0471	metal ion transport
AD867_04885	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AD867_04890	COG4677	pectinesterase activity
AD867_04895	COG0582	viral genome integration into host DNA
AD867_04910	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AD867_04915	COG1882	Formate acetyltransferase
AD867_04920	COG2116	formate transmembrane transporter activity
AD867_04925	COG1944	ATP diphosphatase activity
AD867_04945	COG3385	transposase activity
AD867_04950	COG0501	Belongs to the peptidase M48B family
AD867_04960	COG0539	negative regulation of cytoplasmic translation
AD867_04985	COG3214	Protein conserved in bacteria
AD867_05000	COG3173	Aminoglycoside phosphotransferase
AD867_05005	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AD867_05010	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AD867_05020	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AD867_05030	COG3385	transposase activity
AD867_05035	COG2989	Protein conserved in bacteria
AD867_05040	COG3108	Peptidase M15
AD867_05045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AD867_05050	COG1448	Aminotransferase
AD867_05060	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AD867_05075	COG0308	aminopeptidase N
AD867_05085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AD867_05095	COG2963	transposase activity
AD867_05100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AD867_05110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AD867_05115	COG0431	NADPH-dependent FMN reductase
AD867_05120	COG3677	Transposase
AD867_05130	COG3539	Fimbrial protein
AD867_05140	COG3677	Transposase
AD867_05145	COG3188	usher protein
AD867_05150	COG3539	Fimbrial protein
AD867_05160	COG3539	Fimbrial protein
AD867_05165	COG3121	Chaperone
AD867_05180	COG3217	Mosc domain protein beta barrel domain protein
AD867_05180	COG0633	Ferredoxin
AD867_05190	COG0488	(ABC) transporter
AD867_05195	COG2995	paraquat-inducible protein a
AD867_05200	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AD867_05200	COG3008	intermembrane lipid transfer
AD867_05205	COG3009	Protein conserved in bacteria
AD867_05210	COG3130	regulation of translation
AD867_05220	COG1067	ATP-dependent peptidase activity
AD867_05240	COG3070	regulator of competence-specific genes
AD867_05245	COG2963	transposase activity
AD867_05255	COG1289	transmembrane transporter activity
AD867_05260	COG3304	Inner membrane component domain
AD867_05265	COG0210	DNA helicase
AD867_05285	COG1832	CoA-binding protein
AD867_05305	COG2920	part of a sulfur-relay system
AD867_05310	COG0670	Belongs to the BI1 family
AD867_05320	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AD867_05325	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AD867_05330	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AD867_05335	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AD867_05340	COG1999	signal sequence binding
AD867_05345	COG1773	rubredoxin
AD867_05350	COG1271	oxidase subunit
AD867_05355	COG1294	oxidase, subunit
AD867_05370	COG0489	protein tyrosine kinase activity
AD867_05370	COG3206	protein involved in exopolysaccharide biosynthesis
AD867_05380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AD867_05385	COG1596	polysaccharide export
AD867_05390	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AD867_05410	COG1278	Cold shock
AD867_05415	COG1662	PFAM IS1 transposase
AD867_05420	COG1278	Cold shock
AD867_05435	COG0348	domain, Protein
AD867_05440	COG2205	protein histidine kinase activity
AD867_05440	COG0784	Response regulator, receiver
AD867_05440	COG2198	Histidine kinase
AD867_05445	COG2205	protein histidine kinase activity
AD867_05445	COG2198	Histidine kinase
AD867_05445	COG0784	Response regulator, receiver
AD867_05450	COG1879	ABC-type sugar transport system periplasmic component
AD867_05455	COG0745	RESPONSE REGULATOR receiver
AD867_05460	COG3005	denitrification pathway
AD867_05475	COG1662	PFAM IS1 transposase
AD867_05480	COG3677	Transposase
AD867_05520	COG2233	PERMEase
AD867_05555	COG1309	transcriptional regulator
AD867_05575	COG2822	iron ion transport
AD867_05585	COG1702	phosphate starvation-inducible protein PhoH
AD867_05590	COG2801	Transposase and inactivated derivatives
AD867_05595	COG2963	transposase activity
AD867_05610	COG0582	viral genome integration into host DNA
AD867_05655	COG3344	reverse transcriptase
AD867_05685	COG1309	transcriptional regulator
AD867_05690	COG2963	transposase activity
AD867_05695	COG2801	Transposase and inactivated derivatives
AD867_05700	COG4325	translation initiation factor activity
AD867_05705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AD867_05720	COG2990	Protein conserved in bacteria
AD867_05725	COG0438	transferase activity, transferring glycosyl groups
AD867_05730	COG1662	PFAM IS1 transposase
AD867_05735	COG3677	Transposase
AD867_05760	COG1662	PFAM IS1 transposase
AD867_05815	COG1662	PFAM IS1 transposase
AD867_05840	COG1662	PFAM IS1 transposase
AD867_05860	COG2003	Belongs to the UPF0758 family
AD867_05925	COG3381	protein complex oligomerization
AD867_05950	COG2197	response regulator
AD867_06010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AD867_06035	COG2943	transferase activity, transferring hexosyl groups
AD867_06105	COG2963	transposase activity
AD867_06140	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AD867_06150	COG1560	Kdo2-lipid A biosynthetic process
AD867_06165	COG3038	cytochrome b561
AD867_06200	COG2999	glutathione oxidoreductase activity
AD867_06210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AD867_06220	COG0673	inositol 2-dehydrogenase activity
AD867_06225	COG0728	peptidoglycan biosynthetic process
AD867_06230	COG3418	PFAM FlgN family protein
AD867_06235	COG2747	anti-sigma28 factor FlgM
AD867_06240	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AD867_06245	COG1815	bacterial-type flagellum-dependent cell motility
AD867_06255	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AD867_06260	COG1749	Flagellar hook protein flgE
AD867_06270	COG4786	Flagellar basal body rod
AD867_06285	COG1705	Flagellar rod assembly protein muramidase FlgJ
AD867_06285	COG3951	Flagellar rod assembly protein muramidase FlgJ
AD867_06300	COG1530	ribonuclease E activity
AD867_06310	COG0564	pseudouridine synthase activity
AD867_06320	COG1399	metal-binding, possibly nucleic acid-binding protein
AD867_06340	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AD867_06345	COG1028	Short-chain dehydrogenase reductase Sdr
AD867_06355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AD867_06360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AD867_06365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AD867_06375	COG0470	DNA polymerase III
AD867_06380	COG0084	hydrolase, TatD family'
AD867_06385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AD867_06385	COG1263	PTS System
AD867_06395	COG0537	adenosine 5'-monophosphoramidase activity
AD867_06400	COG5633	Lipoprotein
AD867_06405	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AD867_06425	COG1252	NADH dehydrogenase
AD867_06430	COG3134	Outer membrane lipoprotein
AD867_06435	COG1309	transcriptional regulator
AD867_06445	COG1376	ErfK ybiS ycfS ynhG family protein
AD867_06445	COG1388	LysM domain
AD867_06450	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AD867_06455	COG4763	Acyl-transferase
AD867_06460	COG4591	ABC-type transport system involved in lipoprotein release permease component
AD867_06470	COG4591	ABC-type transport system involved in lipoprotein release permease component
AD867_06485	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AD867_06490	COG1177	transmembrane transport
AD867_06495	COG1176	ABC-type spermidine putrescine transport system, permease component I
AD867_06500	COG3842	ATPase activity
AD867_06515	COG2850	peptidyl-arginine hydroxylation
AD867_06615	COG1802	Transcriptional regulator
AD867_06615	COG4626	Terminase
AD867_06635	COG0745	RESPONSE REGULATOR receiver
AD867_06640	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AD867_06665	COG0538	isocitrate dehydrogenase activity
AD867_06670	COG3677	Transposase
AD867_06670	COG1662	PFAM IS1 transposase
AD867_06675	COG3677	Transposase
AD867_06680	COG2200	EAL domain
AD867_06730	COG2894	cell division
AD867_06750	COG2963	transposase activity
AD867_06765	COG2963	transposase activity
AD867_06770	COG2801	Transposase and inactivated derivatives
AD867_06785	COG0179	Fumarylacetoacetate (FAA) hydrolase
AD867_06805	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AD867_06810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AD867_06830	COG2719	SpoVR family
AD867_06840	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AD867_06855	COG1619	proteins homologs of microcin C7 resistance protein MccF
AD867_06865	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AD867_06880	COG0157	Belongs to the NadC ModD family
AD867_06885	COG0500	methyltransferase
AD867_06890	COG1120	ATPase activity
AD867_06910	COG1662	PFAM IS1 transposase
AD867_06925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AD867_06925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AD867_06925	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AD867_06930	COG1461	Dihydroxyacetone kinase
AD867_06935	COG2376	Dihydroxyacetone kinase
AD867_06940	COG3284	Transcriptional regulator
AD867_06945	COG3468	outer membrane autotransporter barrel domain protein
AD867_06955	COG0012	GTP binding
AD867_06970	COG0659	secondary active sulfate transmembrane transporter activity
AD867_06975	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AD867_07000	COG2890	protein-(glutamine-N5) methyltransferase activity
AD867_07005	COG3094	Invasion gene expression up-regulator, SirB
AD867_07010	COG2912	Transglutaminase-like superfamily
AD867_07025	COG0387	Pfam Sodium calcium exchanger
AD867_07030	COG4572	Cation transport regulator
AD867_07035	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AD867_07040	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AD867_07045	COG4932	domain protein
AD867_07050	COG2197	response regulator
AD867_07055	COG3850	Histidine kinase
AD867_07065	COG2223	nitrite transmembrane transporter activity
AD867_07070	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AD867_07075	COG1140	nitrate reductase beta subunit
AD867_07080	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AD867_07085	COG2181	nitrate reductase activity
AD867_07095	COG0788	formyltetrahydrofolate deformylase activity
AD867_07105	COG1752	Esterase of the alpha-beta hydrolase superfamily
AD867_07110	COG0745	RESPONSE REGULATOR receiver
AD867_07115	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AD867_07120	COG2916	Histone family protein nucleoid-structuring protein H-NS
AD867_07125	COG1435	thymidine kinase activity
AD867_07130	COG3385	transposase activity
AD867_07135	COG1454	alcohol dehydrogenase
AD867_07135	COG1012	belongs to the aldehyde dehydrogenase family
AD867_07140	COG2095	MarC family integral membrane protein
AD867_07145	COG1662	PFAM IS1 transposase
AD867_07150	COG3677	Transposase
AD867_07155	COG4166	transmembrane transport
AD867_07160	COG0601	transmembrane transport
AD867_07165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AD867_07170	COG0444	Belongs to the ABC transporter superfamily
AD867_07175	COG4608	Belongs to the ABC transporter superfamily
AD867_07195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AD867_07210	COG2350	Protein conserved in bacteria
AD867_07215	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AD867_07220	COG1607	acyl-coa hydrolase
AD867_07235	COG3047	cAMP biosynthetic process
AD867_07240	COG3685	Protein conserved in bacteria
AD867_07245	COG3685	Protein conserved in bacteria
AD867_07250	COG3729	General stress protein
AD867_07265	COG0134	indole-3-glycerol-phosphate synthase activity
AD867_07265	COG0135	phosphoribosylanthranilate isomerase activity
AD867_07270	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AD867_07270	COG0512	Glutamine amidotransferase of anthranilate synthase
AD867_07275	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AD867_07280	COG0613	PHP domain protein
AD867_07285	COG0009	L-threonylcarbamoyladenylate synthase
AD867_07295	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AD867_07300	COG1028	Short-chain dehydrogenase reductase Sdr
AD867_07310	COG0616	signal peptide processing
AD867_07325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AD867_07330	COG0583	DNA-binding transcription factor activity
AD867_07350	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AD867_07360	COG0671	phosphoesterase, PA-phosphatase related
AD867_07365	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AD867_07370	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AD867_07380	COG0023	Translation Initiation Factor
AD867_07390	COG1349	DNA-binding transcription factor activity
AD867_07400	COG5001	Diguanylate cyclase
AD867_07405	COG5001	Diguanylate cyclase
AD867_07410	COG5001	Diguanylate cyclase
AD867_07425	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AD867_07425	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AD867_07430	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AD867_07440	COG2852	Protein conserved in bacteria
AD867_07445	COG4172	Belongs to the ABC transporter superfamily
AD867_07450	COG4172	Belongs to the ABC transporter superfamily
AD867_07455	COG4171	peptide transport system, permease
AD867_07460	COG4168	peptide transport system, permease
AD867_07465	COG4166	transmembrane transport
AD867_07480	COG0531	amino acid
AD867_07485	COG0174	glutamine synthetase
AD867_07495	COG1396	sequence-specific DNA binding
AD867_07495	COG1917	Cupin 2, conserved barrel domain protein
AD867_07500	COG1012	belongs to the aldehyde dehydrogenase family
AD867_07505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AD867_07510	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AD867_07515	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AD867_07520	COG1842	Phage shock protein A
AD867_07530	COG1983	PspC domain protein
AD867_07540	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AD867_07550	COG3677	Transposase
AD867_07555	COG1662	PFAM IS1 transposase
AD867_07565	COG1653	transport
AD867_07570	COG1653	transport
AD867_07575	COG1175	transmembrane transport
AD867_07580	COG0395	ABC-type sugar transport system, permease component
AD867_07585	COG1063	alcohol dehydrogenase
AD867_07600	COG1554	hydrolase, family 65, central catalytic
AD867_07605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AD867_07625	COG1609	Transcriptional regulator
AD867_07630	COG3106	COG3106 Predicted ATPase
AD867_07640	COG3283	Transcriptional regulator of aromatic amino acids metabolism
AD867_07645	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AD867_07650	COG4948	Mandelate Racemase Muconate Lactonizing
AD867_07655	COG2866	Carboxypeptidase
AD867_07660	COG0702	epimerase
AD867_07670	COG3547	Transposase (IS116 IS110 IS902 family)
AD867_07680	COG1073	alpha beta
AD867_07705	COG2963	transposase activity
AD867_07710	COG3756	Protein conserved in bacteria
AD867_07715	COG1484	DNA-dependent DNA replication
AD867_07765	COG1662	PFAM IS1 transposase
AD867_07770	COG3677	Transposase
AD867_07825	COG4974	Belongs to the 'phage' integrase family
AD867_07845	COG3677	Transposase
AD867_07850	COG1662	PFAM IS1 transposase
AD867_07870	COG5301	cellulose 1,4-beta-cellobiosidase activity
AD867_07880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AD867_07885	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AD867_07890	COG1121	(ABC) transporter
AD867_07900	COG0582	viral genome integration into host DNA
AD867_07905	COG3677	Transposase
AD867_08015	COG3677	Transposase
AD867_08040	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AD867_08065	COG2995	paraquat-inducible protein a
AD867_08070	COG1956	GAF domain-containing protein
AD867_08080	COG0793	Belongs to the peptidase S41A family
AD867_08090	COG2814	Major facilitator Superfamily
AD867_08095	COG1414	Transcriptional regulator
AD867_08125	COG1278	Cold shock
AD867_08130	COG2226	methyltransferase
AD867_08150	COG3677	Transposase
AD867_08160	COG3716	PTS system mannose fructose sorbose family IID component
AD867_08165	COG3715	PTS system
AD867_08170	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AD867_08170	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AD867_08180	COG1253	flavin adenine dinucleotide binding
AD867_08185	COG2200	EAL domain
AD867_08190	COG1760	l-serine dehydratase
AD867_08200	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AD867_08215	COG0251	oxidation-reduction process
AD867_08220	COG1199	ATP-dependent helicase activity
AD867_08225	COG1214	PFAM Peptidase M22, glycoprotease
AD867_08230	COG3065	identical protein binding
AD867_08235	COG0318	PFAM AMP-dependent synthetase and ligase
AD867_08240	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AD867_08245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AD867_08250	COG4638	Rieske (2fe-2S)
AD867_08280	COG2203	Gaf domain
AD867_08280	COG2199	diguanylate cyclase activity
AD867_08285	COG3042	response to heat
AD867_08290	COG3189	MarR family transcriptional regulator
AD867_08315	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AD867_08320	COG2199	diguanylate cyclase activity
AD867_08335	COG2766	serine protein kinase
AD867_08340	COG3713	MltA-interacting MipA family protein
AD867_08345	COG0656	L-ascorbic acid biosynthetic process
AD867_08350	COG0676	glucose-6-phosphate 1-epimerase activity
AD867_08355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AD867_08365	COG3139	Protein of unknown function (DUF1315)
AD867_08370	COG1063	alcohol dehydrogenase
AD867_08375	COG2271	Major facilitator Superfamily
AD867_08385	COG0191	fructose-bisphosphate aldolase activity
AD867_08390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AD867_08395	COG0667	Aldo Keto reductase
AD867_08400	COG1349	DNA-binding transcription factor activity
AD867_08405	COG2814	Major facilitator Superfamily
AD867_08410	COG1335	isochorismatase
AD867_08415	COG0252	asparaginase activity
AD867_08420	COG0616	signal peptide processing
AD867_08430	COG0778	Nitroreductase
AD867_08445	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AD867_08460	COG2963	transposase activity
AD867_08475	COG0494	nUDIX hydrolase
AD867_08480	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AD867_08485	COG2897	thiosulfate sulfurtransferase activity
AD867_08490	COG2897	thiosulfate sulfurtransferase activity
AD867_08495	COG4136	ATPase activity
AD867_08510	COG3385	transposase activity
AD867_08515	COG4134	Bacterial extracellular solute-binding protein
AD867_08520	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AD867_08525	COG0398	Pfam SNARE associated Golgi protein
AD867_08535	COG0398	Pfam SNARE associated Golgi protein
AD867_08540	COG0708	Exodeoxyribonuclease III
AD867_08570	COG3678	ATP-independent chaperone mediated protein folding
AD867_08595	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AD867_08600	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AD867_08610	COG1447	Phosphotransferase system cellobiose-specific component IIA
AD867_08615	COG2169	Transcriptional regulator
AD867_08615	COG1917	Cupin 2, conserved barrel domain protein
AD867_08620	COG2169	Transcriptional regulator
AD867_08620	COG1917	Cupin 2, conserved barrel domain protein
AD867_08625	COG1662	PFAM IS1 transposase
AD867_08630	COG3677	Transposase
AD867_08640	COG1486	melibiose metabolic process
AD867_08650	COG0753	catalase activity
AD867_08665	COG1662	PFAM IS1 transposase
AD867_08670	COG3677	Transposase
AD867_08680	COG1988	membrane-bound metal-dependent
AD867_08685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AD867_08705	COG1105	Belongs to the carbohydrate kinase PfkB family
AD867_08710	COG3137	Salt-induced outer membrane protein
AD867_08725	COG1662	PFAM IS1 transposase
AD867_08730	COG3677	Transposase
AD867_08780	COG0386	Belongs to the glutathione peroxidase family
AD867_08790	COG0791	NLP P60 protein
AD867_08795	COG2200	EAL domain
AD867_08805	COG4256	Hemin uptake protein
AD867_08825	COG0574	Belongs to the PEP-utilizing enzyme family
AD867_08825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AD867_08830	COG0318	PFAM AMP-dependent synthetase and ligase
AD867_08835	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AD867_08840	COG0644	oxidoreductase
AD867_08845	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AD867_08850	COG2086	electron transfer activity
AD867_08870	COG3119	arylsulfatase activity
AD867_08895	COG3677	Transposase
AD867_08900	COG1662	PFAM IS1 transposase
AD867_08945	COG0484	heat shock protein binding
AD867_08950	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AD867_08955	COG1403	HNH endonuclease
AD867_08975	COG2026	Addiction module toxin, RelE StbE family
AD867_08980	COG3077	Addiction module antitoxin, RelB DinJ family
AD867_08995	COG0477	Major facilitator Superfamily
AD867_09000	COG0246	Mannitol dehydrogenase
AD867_09010	COG1802	Transcriptional regulator
AD867_09020	COG0339	signal peptide processing
AD867_09025	COG1546	Belongs to the CinA family
AD867_09050	COG2814	Major facilitator Superfamily
AD867_09055	COG0697	spore germination
AD867_09065	COG4977	sequence-specific DNA binding
AD867_09070	COG1846	Transcriptional regulator
AD867_09105	COG2199	diguanylate cyclase activity
AD867_09110	COG0246	Mannitol dehydrogenase
AD867_09140	COG3781	membrane
AD867_09165	COG2963	transposase activity
AD867_09200	COG2963	transposase activity
AD867_09210	COG2801	Transposase and inactivated derivatives
AD867_09215	COG2963	transposase activity
AD867_09220	COG4948	Mandelate Racemase Muconate Lactonizing
AD867_09250	COG0243	molybdopterin cofactor binding
AD867_09335	COG0437	4 iron, 4 sulfur cluster binding
AD867_09340	COG3302	dmso reductase anchor subunit
AD867_09345	COG3381	protein complex oligomerization
AD867_09355	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AD867_09360	COG1940	carbohydrate kinase activity
AD867_09365	COG0583	DNA-binding transcription factor activity
AD867_09385	COG3591	Belongs to the peptidase S1B family
AD867_09400	COG0628	permease
AD867_09405	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AD867_09410	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AD867_09420	COG0531	amino acid
AD867_09430	COG3136	membrane protein required for alginate biosynthesis
AD867_09435	COG0745	RESPONSE REGULATOR receiver
AD867_09445	COG2205	protein histidine kinase activity
AD867_09460	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AD867_09460	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AD867_09470	COG5339	Protein conserved in bacteria
AD867_09485	COG3250	beta-galactosidase activity
AD867_09490	COG1309	transcriptional regulator
AD867_09500	COG3677	Transposase
AD867_09510	COG1609	Transcriptional regulator
AD867_09515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AD867_09515	COG1263	PTS System
AD867_09520	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AD867_09530	COG0673	inositol 2-dehydrogenase activity
AD867_09570	COG4659	FMN binding
AD867_09580	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AD867_09590	COG3104	oligopeptide transport
AD867_09595	COG0625	glutathione transferase activity
AD867_09625	COG2963	transposase activity
AD867_09635	COG3133	Outer membrane lipoprotein
AD867_09650	COG1566	PFAM secretion protein HlyD family protein
AD867_09660	COG2032	superoxide dismutase activity
AD867_09665	COG4989	oxidoreductase activity
AD867_09670	COG3313	Fe-S protein
AD867_09675	COG1309	transcriptional regulator
AD867_09680	COG1902	pentaerythritol trinitrate reductase activity
AD867_09685	COG0346	lactoylglutathione lyase activity
AD867_09700	COG0675	Transposase, IS605 OrfB family
AD867_09705	COG1943	Transposase
AD867_09710	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AD867_09715	COG0791	NLP P60 protein
AD867_09720	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AD867_09725	COG2814	Major facilitator Superfamily
AD867_09740	COG0583	DNA-binding transcription factor activity
AD867_09745	COG2814	Major facilitator Superfamily
AD867_09750	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AD867_09755	COG0307	riboflavin synthase, alpha
AD867_09765	COG3468	outer membrane autotransporter barrel domain protein
AD867_09795	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AD867_09800	COG0437	4 iron, 4 sulfur cluster binding
AD867_09815	COG2414	aldehyde ferredoxin oxidoreductase
AD867_09820	COG0437	4 iron, 4 sulfur cluster binding
AD867_09830	COG3677	Transposase
AD867_09840	COG0469	pyruvate kinase activity
AD867_09845	COG4238	major outer membrane lipoprotein
AD867_09850	COG1376	ErfK ybiS ycfS ynhG family protein
AD867_09865	COG0719	Fe-S assembly protein
AD867_09870	COG0396	ATPase activity
AD867_09875	COG0719	Fe-S assembly protein
AD867_09880	COG0316	Belongs to the HesB IscA family
AD867_09890	COG2050	protein possibly involved in aromatic compounds catabolism
AD867_09895	COG0277	FAD linked oxidase domain protein
AD867_09895	COG0247	lactate metabolic process
AD867_09900	COG0628	permease
AD867_09910	COG0738	Major facilitator superfamily
AD867_09930	COG1662	PFAM IS1 transposase
AD867_09935	COG3119	arylsulfatase activity
AD867_09940	COG0641	radical SAM
AD867_09950	COG4771	TonB-dependent receptor
AD867_09955	COG1662	PFAM IS1 transposase
AD867_09960	COG3677	Transposase
AD867_09965	COG0612	Peptidase, M16
AD867_09970	COG3677	Transposase
AD867_09975	COG1662	PFAM IS1 transposase
AD867_09985	COG0076	glutamate decarboxylase activity
AD867_09990	COG0531	amino acid
AD867_10005	COG2202	Pas domain
AD867_10005	COG2200	EAL domain
AD867_10005	COG2199	diguanylate cyclase activity
AD867_10015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AD867_10020	COG0444	Belongs to the ABC transporter superfamily
AD867_10025	COG4608	Belongs to the ABC transporter superfamily
AD867_10030	COG1764	response to oxidative stress
AD867_10045	COG1064	alcohol dehydrogenase
AD867_10050	COG3093	addiction module antidote protein HigA
AD867_10055	COG2864	formate dehydrogenase
AD867_10060	COG0437	4 iron, 4 sulfur cluster binding
AD867_10065	COG0243	molybdopterin cofactor binding
AD867_10065	COG3383	formate dehydrogenase (NAD+) activity
AD867_10070	COG0243	molybdopterin cofactor binding
AD867_10070	COG3383	formate dehydrogenase (NAD+) activity
AD867_10075	COG0697	spore germination
AD867_10090	COG4886	Leucine-rich repeat (LRR) protein
AD867_10100	COG3677	Transposase
AD867_10110	COG2223	nitrite transmembrane transporter activity
AD867_10135	COG1802	Transcriptional regulator
AD867_10140	COG2130	NADP-dependent
AD867_10150	COG2963	transposase activity
AD867_10155	COG1247	-acetyltransferase
AD867_10160	COG3238	Protein conserved in bacteria
AD867_10190	COG1177	transmembrane transport
AD867_10210	COG0675	Transposase, IS605 OrfB family
AD867_10215	COG0675	Transposase, IS605 OrfB family
AD867_10230	COG0500	methyltransferase
AD867_10235	COG1275	C4-dicarboxylate transporter malic acid transport protein
AD867_10240	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AD867_10245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AD867_10250	COG2841	Protein conserved in bacteria
AD867_10265	COG5383	Protein conserved in bacteria
AD867_10270	COG0583	DNA-binding transcription factor activity
AD867_10275	COG0840	transmembrane signaling receptor activity
AD867_10280	COG2963	transposase activity
AD867_10285	COG2801	Transposase and inactivated derivatives
AD867_10295	COG2963	transposase activity
AD867_10320	COG3038	cytochrome b561
AD867_10325	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AD867_10330	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AD867_10335	COG1012	belongs to the aldehyde dehydrogenase family
AD867_10365	COG1643	Atp-dependent helicase
AD867_10405	COG2267	carboxylic ester hydrolase activity
AD867_10410	COG4589	Belongs to the CDS family
AD867_10415	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AD867_10425	COG1662	PFAM IS1 transposase
AD867_10435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AD867_10440	COG2911	Protein conserved in bacteria
AD867_10450	COG3784	Protein of unknown function (DUF1318)
AD867_10460	COG3677	Transposase
AD867_10470	COG3187	Heat shock protein
AD867_10475	COG3042	response to heat
AD867_10480	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AD867_10480	COG1013	pyruvate-flavodoxin oxidoreductase activity
AD867_10480	COG0674	pyruvate-flavodoxin oxidoreductase activity
AD867_10480	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AD867_10490	COG0589	response to stress
AD867_10500	COG0513	Belongs to the DEAD box helicase family
AD867_10555	COG2207	Transcriptional regulator
AD867_10565	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AD867_10570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AD867_10575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AD867_10580	COG0589	response to stress
AD867_10605	COG0668	transmembrane transport
AD867_10610	COG4166	transmembrane transport
AD867_10615	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AD867_10665	COG1276	copper resistance
AD867_10670	COG1276	copper resistance
AD867_10675	COG2372	response to copper ion
AD867_10690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AD867_10695	COG1770	oligopeptidase
AD867_10700	COG2979	Protein of unknown function (DUF533)
AD867_10725	COG0800	Aldolase
AD867_10730	COG0129	dihydroxy-acid dehydratase activity
AD867_10735	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AD867_10740	COG1737	Transcriptional regulator
AD867_10745	COG0469	pyruvate kinase activity
AD867_10755	COG0739	heme binding
AD867_10760	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AD867_10770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AD867_10795	COG0217	transcriptional regulatory protein
AD867_10800	COG0494	nUDIX hydrolase
AD867_10810	COG1335	isochorismatase
AD867_10815	COG3547	Transposase (IS116 IS110 IS902 family)
AD867_10945	COG3547	Transposase (IS116 IS110 IS902 family)
AD867_10975	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AD867_11045	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AD867_11060	COG0243	molybdopterin cofactor binding
AD867_11065	COG3005	denitrification pathway
AD867_11075	COG3102	Protein conserved in bacteria
AD867_11085	COG3755	Protein conserved in bacteria
AD867_11115	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AD867_11155	COG0745	RESPONSE REGULATOR receiver
AD867_11165	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AD867_11170	COG0840	transmembrane signaling receptor activity
AD867_11175	COG0840	transmembrane signaling receptor activity
AD867_11180	COG0835	chemotaxis
AD867_11185	COG0643	Histidine kinase
AD867_11185	COG2198	Histidine kinase
AD867_11190	COG1360	Flagellar Motor Protein
AD867_11195	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AD867_11210	COG1662	PFAM IS1 transposase
AD867_11225	COG1877	trehalose-phosphatase activity
AD867_11230	COG1172	Belongs to the binding-protein-dependent transport system permease family
AD867_11245	COG1528	Iron-storage protein
AD867_11265	COG1528	Iron-storage protein
AD867_11275	COG0814	amino acid
AD867_11280	COG3318	Belongs to the UPF0149 family
AD867_11280	COG3012	SEC-C Motif Domain Protein
AD867_11310	COG2197	response regulator
AD867_11325	COG2197	response regulator
AD867_11365	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AD867_11370	COG1516	flagellar protein fliS
AD867_11380	COG0366	Alpha amylase catalytic
AD867_11390	COG2391	methyltransferase activity
AD867_11395	COG0425	Belongs to the sulfur carrier protein TusA family
AD867_11405	COG0675	Transposase, IS605 OrfB family
AD867_11410	COG0675	Transposase, IS605 OrfB family
AD867_11415	COG0675	Transposase, IS605 OrfB family
AD867_11420	COG1943	Transposase
AD867_11435	COG2207	Transcriptional regulator
AD867_11440	COG1881	PFAM PEBP family protein
AD867_11445	COG2076	Multidrug Resistance protein
AD867_11470	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AD867_11475	COG1317	bacterial-type flagellum organization
AD867_11480	COG1157	protein secretion by the type III secretion system
AD867_11490	COG3144	bacterial-type flagellum assembly
AD867_11495	COG1580	Controls the rotational direction of flagella during chemotaxis
AD867_11500	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AD867_11505	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AD867_11510	COG3190	flagellar
AD867_11515	COG1338	Plays a role in the flagellum-specific transport system
AD867_11520	COG1987	bacterial-type flagellum assembly
AD867_11525	COG1684	flagellar biosynthetic protein fliR
AD867_11530	COG2197	response regulator
AD867_11560	COG3706	GGDEF domain
AD867_11565	COG5475	Uncharacterized small protein (DUF2158)
AD867_11570	COG2354	Protein conserved in bacteria
AD867_11575	COG0697	spore germination
AD867_11580	COG3727	T/G mismatch-specific endonuclease activity
AD867_11585	COG0270	DNA (cytosine-5-)-methyltransferase activity
AD867_11600	COG2801	Transposase and inactivated derivatives
AD867_11605	COG2963	transposase activity
AD867_11620	COG2963	transposase activity
AD867_11645	COG2205	protein histidine kinase activity
AD867_11650	COG0745	RESPONSE REGULATOR receiver
AD867_11655	COG2351	hydroxyisourate hydrolase activity
AD867_11670	COG3443	Belongs to the bacterial solute-binding protein 9 family
AD867_11685	COG0500	methyltransferase
AD867_11710	COG1662	PFAM IS1 transposase
AD867_11735	COG4386	tail sheath protein
AD867_11775	COG3436	PFAM IS66 Orf2 family protein
AD867_11815	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AD867_11820	COG1403	HNH endonuclease
AD867_11915	COG0477	Major facilitator Superfamily
AD867_11920	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AD867_11935	COG0534	Mate efflux family protein
AD867_11940	COG0534	Mate efflux family protein
AD867_11945	COG0534	Mate efflux family protein
AD867_11955	COG0583	DNA-binding transcription factor activity
AD867_11960	COG0583	DNA-binding transcription factor activity
AD867_11970	COG1376	ErfK ybiS ycfS ynhG family protein
AD867_11985	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
AD867_12020	COG4917	ethanolamine utilization protein
AD867_12030	COG1289	transmembrane transporter activity
AD867_12040	COG3436	PFAM IS66 Orf2 family protein
AD867_12070	COG4372	Transposase
AD867_12085	COG4372	Transposase
AD867_12105	COG2963	transposase activity
AD867_12115	COG3436	PFAM IS66 Orf2 family protein
AD867_12130	COG2925	Exonuclease
AD867_12135	COG0425	Belongs to the sulfur carrier protein TusA family
AD867_12140	COG2391	methyltransferase activity
AD867_12145	COG0531	amino acid
AD867_12150	COG0583	DNA-binding transcription factor activity
AD867_12155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AD867_12160	COG4115	mRNA cleavage
AD867_12165	COG1662	PFAM IS1 transposase
AD867_12310	COG0438	transferase activity, transferring glycosyl groups
AD867_12315	COG2327	Polysaccharide pyruvyl transferase
AD867_12320	COG2244	polysaccharide biosynthetic process
AD867_12325	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AD867_12330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AD867_12335	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AD867_12335	COG0662	Cupin 2, conserved barrel domain protein
AD867_12340	COG0297	glycogen (starch) synthase activity
AD867_12345	COG1051	belongs to the nudix hydrolase family
AD867_12350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AD867_12355	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AD867_12360	COG0110	maltose O-acetyltransferase activity
AD867_12375	COG0438	transferase activity, transferring glycosyl groups
AD867_12380	COG1045	serine acetyltransferase
AD867_12385	COG0463	Glycosyl transferase, family 2
AD867_12390	COG0463	Glycosyl transferase, family 2
AD867_12395	COG0489	protein tyrosine kinase activity
AD867_12395	COG3206	protein involved in exopolysaccharide biosynthesis
AD867_12400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AD867_12405	COG1596	polysaccharide export
AD867_12415	COG2982	Protein involved in outer membrane biogenesis
AD867_12425	COG0572	uridine kinase
AD867_12450	COG2205	protein histidine kinase activity
AD867_12455	COG0745	RESPONSE REGULATOR receiver
AD867_12490	COG1063	alcohol dehydrogenase
AD867_12500	COG3775	system Galactitol-specific IIC component
AD867_12505	COG3414	Phosphotransferase system galactitol-specific IIB component
AD867_12510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AD867_12525	COG1830	Aldolase
AD867_12535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AD867_12540	COG2188	Transcriptional regulator
AD867_12545	COG3757	hydrolase, family 25
AD867_12550	COG0351	phosphomethylpyrimidine kinase
AD867_12570	COG5455	response to cobalt ion
AD867_12580	COG3188	usher protein
AD867_12585	COG3121	Chaperone
AD867_12590	COG3539	Fimbrial protein
AD867_12595	COG1662	PFAM IS1 transposase
AD867_12605	COG0489	protein tyrosine kinase activity
AD867_12635	COG3677	Transposase
AD867_12645	COG3831	ATPase activity
AD867_12650	COG3831	ATPase activity
AD867_12655	COG3831	ATPase activity
AD867_12660	COG3831	ATPase activity
AD867_12675	COG0714	Associated with various cellular activities
AD867_12680	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AD867_12685	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AD867_12690	COG4715	Zinc finger, swim domain protein
AD867_12695	COG1662	PFAM IS1 transposase
AD867_12700	COG4808	Protein conserved in bacteria
AD867_12705	COG1662	PFAM IS1 transposase
AD867_12720	COG3275	phosphorelay sensor kinase activity
AD867_12740	COG0500	methyltransferase
AD867_12760	COG5301	cellulose 1,4-beta-cellobiosidase activity
AD867_12775	COG1662	PFAM IS1 transposase
AD867_12780	COG0582	viral genome integration into host DNA
AD867_12785	COG0789	Transcriptional regulator
AD867_12815	COG1174	glycine betaine transport
AD867_12820	COG1125	glycine betaine transport
AD867_12825	COG1174	glycine betaine transport
AD867_12830	COG1732	Glycine betaine
AD867_12835	COG1472	Belongs to the glycosyl hydrolase 3 family
AD867_12840	COG0277	FAD linked oxidase domain protein
AD867_12845	COG1686	Belongs to the peptidase S11 family
AD867_12855	COG0586	Pfam SNARE associated Golgi protein
AD867_12885	COG1346	cytolysis
AD867_12895	COG2949	membrane
AD867_12905	COG0493	'glutamate synthase
AD867_12915	COG4211	Belongs to the binding-protein-dependent transport system permease family
AD867_12920	COG1129	ABC transporter
AD867_12925	COG1879	ABC-type sugar transport system periplasmic component
AD867_12930	COG1609	Transcriptional regulator
AD867_12940	COG2311	Membrane
AD867_12970	COG0833	amino acid
AD867_12975	COG0583	DNA-binding transcription factor activity
AD867_12980	COG2855	membrane
AD867_12990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AD867_12990	COG1522	sequence-specific DNA binding
AD867_12995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AD867_13005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AD867_13010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AD867_13015	COG2313	pseudouridylate synthase activity
AD867_13020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AD867_13025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AD867_13025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AD867_13025	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AD867_13030	COG1105	Belongs to the carbohydrate kinase PfkB family
AD867_13035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AD867_13035	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AD867_13040	COG2814	Major facilitator Superfamily
AD867_13045	COG1662	PFAM IS1 transposase
AD867_13060	COG0246	Mannitol dehydrogenase
AD867_13065	COG0523	cobalamin synthesis protein
AD867_13070	COG0671	phosphoesterase, PA-phosphatase related
AD867_13075	COG0791	NLP P60 protein
AD867_13080	COG2200	EAL domain
AD867_13085	COG4166	transmembrane transport
AD867_13090	COG4174	ABC transporter (Permease)
AD867_13095	COG4239	(ABC) transporter, permease
AD867_13100	COG4172	Belongs to the ABC transporter superfamily
AD867_13110	COG2814	Major facilitator Superfamily
AD867_13115	COG1187	pseudouridine synthase activity
AD867_13120	COG1061	Type III restriction enzyme res subunit
AD867_13140	COG3083	sulfuric ester hydrolase activity
AD867_13150	COG3468	outer membrane autotransporter barrel domain protein
AD867_13160	COG2197	response regulator
AD867_13165	COG4235	cytochrome complex assembly
AD867_13165	COG3088	subunit of a heme lyase
AD867_13170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AD867_13175	COG1138	Cytochrome C-type biogenesis protein
AD867_13185	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AD867_13190	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AD867_13195	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AD867_13205	COG3005	denitrification pathway
AD867_13210	COG3043	anaerobic respiration
AD867_13215	COG0348	domain, Protein
AD867_13220	COG0437	4 iron, 4 sulfur cluster binding
AD867_13230	COG3062	negative regulation of establishment of protein localization
AD867_13235	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AD867_13235	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
AD867_13260	COG4615	Cyclic peptide transporter
AD867_13265	COG3145	DNA-N1-methyladenine dioxygenase activity
AD867_13270	COG2169	Transcriptional regulator
AD867_13270	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AD867_13275	COG1477	protein flavinylation
AD867_13290	COG2198	Histidine kinase
AD867_13290	COG0642	Histidine kinase
AD867_13295	COG2197	response regulator
AD867_13300	COG2205	protein histidine kinase activity
AD867_13300	COG0784	Response regulator, receiver
AD867_13305	COG4676	Protein conserved in bacteria
AD867_13310	COG5445	Predicted secreted protein (DUF2300)
AD867_13315	COG2373	Large extracellular alpha-helical protein
AD867_13335	COG3234	Protein of unknown function (DUF1175)
AD867_13345	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AD867_13375	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AD867_13380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AD867_13385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AD867_13390	COG3642	lipopolysaccharide core region biosynthetic process
AD867_13395	COG0583	DNA-binding transcription factor activity
AD867_13400	COG0584	glycerophosphoryl diester phosphodiesterase
AD867_13405	COG2271	Major facilitator Superfamily
AD867_13410	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AD867_13420	COG0247	lactate metabolic process
AD867_13425	COG5464	transposase or invertase
AD867_13430	COG3836	Belongs to the HpcH HpaI aldolase family
AD867_13495	COG0318	PFAM AMP-dependent synthetase and ligase
AD867_13505	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AD867_13520	COG1169	isochorismate synthase
AD867_13525	COG4575	ribosome binding
AD867_13530	COG2153	protein acetylation
AD867_13545	COG3677	Transposase
AD867_13555	COG2234	aminopeptidase activity
AD867_13570	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AD867_13575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AD867_13585	COG0839	Belongs to the complex I subunit 6 family
AD867_13590	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AD867_13605	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AD867_13610	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AD867_13630	COG0583	DNA-binding transcription factor activity
AD867_13635	COG0436	Aminotransferase
AD867_13645	COG0471	metal ion transport
AD867_13645	COG0490	domain, Protein
AD867_13650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AD867_13670	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AD867_13675	COG0857	belongs to the CobB CobQ family
AD867_13675	COG0280	phosphate acetyltransferase
AD867_13680	COG1288	antiporter activity
AD867_13690	COG0622	Phosphoesterase
AD867_13695	COG0625	glutathione transferase activity
AD867_13700	COG0625	glutathione transferase activity
AD867_13705	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AD867_13710	COG1090	epimerase
AD867_13715	COG5464	transposase or invertase
AD867_13720	COG4598	ABC transporter
AD867_13725	COG4160	amino acid transport
AD867_13730	COG4215	(ABC) transporter
AD867_13735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AD867_13740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AD867_13745	COG0163	prenyltransferase activity
AD867_13750	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AD867_13755	COG1286	toxin biosynthetic process
AD867_13760	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AD867_13765	COG0285	dihydrofolate synthase activity
AD867_13775	COG0586	Pfam SNARE associated Golgi protein
AD867_13785	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AD867_13805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AD867_13820	COG3101	peptidyl-lysine hydroxylation
AD867_13825	COG0730	response to heat
AD867_13855	COG3539	Fimbrial protein
AD867_13860	COG3539	Fimbrial protein
AD867_13865	COG3539	Fimbrial protein
AD867_13880	COG3539	Fimbrial protein
AD867_13890	COG3677	Transposase
AD867_13895	COG2062	phosphohistidine phosphatase, SixA
AD867_13910	COG3691	Protein conserved in bacteria
AD867_13955	COG3385	transposase activity
AD867_13970	COG2610	gluconate transmembrane transporter activity
AD867_13980	COG0477	Major facilitator Superfamily
AD867_13985	COG1566	PFAM secretion protein HlyD family protein
AD867_13990	COG2197	response regulator
AD867_13995	COG0784	Response regulator, receiver
AD867_13995	COG2198	Histidine kinase
AD867_13995	COG2205	protein histidine kinase activity
AD867_13995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AD867_14000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AD867_14005	COG0679	Auxin Efflux Carrier
AD867_14010	COG0028	Belongs to the TPP enzyme family
AD867_14040	COG1560	Kdo2-lipid A biosynthetic process
AD867_14045	COG0436	Aminotransferase
AD867_14055	COG3279	Response regulator of the LytR AlgR family
AD867_14070	COG1363	Peptidase, m42
AD867_14080	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AD867_14115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AD867_14135	COG3415	Transposase
AD867_14140	COG3415	Transposase
AD867_14170	COG0583	DNA-binding transcription factor activity
AD867_14175	COG0385	Bile acid
AD867_14180	COG3530	Putative quorum-sensing-regulated virulence factor
AD867_14200	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AD867_14205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AD867_14210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AD867_14215	COG2190	(PTS) system
AD867_14235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AD867_14245	COG4208	sulfate ABC transporter
AD867_14250	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AD867_14255	COG4150	thiosulfate binding
AD867_14260	COG1028	Short-chain dehydrogenase reductase Sdr
AD867_14280	COG2837	iron assimilation
AD867_14295	COG0456	acetyltransferase
AD867_14300	COG0860	N-Acetylmuramoyl-L-alanine amidase
AD867_14315	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AD867_14320	COG4816	utilization protein
AD867_14355	COG0076	glutamate decarboxylase activity
AD867_14360	COG0076	glutamate decarboxylase activity
AD867_14365	COG0531	amino acid
AD867_14370	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AD867_14395	COG4819	ethanolamine utilization protein
AD867_14400	COG4917	ethanolamine utilization protein
AD867_14405	COG4810	utilization protein
AD867_14410	COG0280	phosphate acetyltransferase
AD867_14410	COG0281	malic enzyme
AD867_14420	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AD867_14425	COG5342	invasion associated locus B
AD867_14435	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AD867_14435	COG0493	'glutamate synthase
AD867_14445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AD867_14455	COG1393	Belongs to the ArsC family
AD867_14470	COG0400	carboxylic ester hydrolase activity
AD867_14480	COG2321	neutral zinc metallopeptidase
AD867_14495	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AD867_14505	COG2716	regulation of RNA biosynthetic process
AD867_14510	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AD867_14515	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AD867_14520	COG0651	ATP synthesis coupled electron transport
AD867_14525	COG0651	ATP synthesis coupled electron transport
AD867_14530	COG0650	Formate hydrogenlyase subunit 4
AD867_14535	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AD867_14540	COG4237	Hydrogenase 4 membrane
AD867_14545	COG0651	ATP synthesis coupled electron transport
AD867_14555	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AD867_14560	COG3260	NADH ubiquinone oxidoreductase 20
AD867_14570	COG3604	Transcriptional regulator
AD867_14575	COG3604	Transcriptional regulator
AD867_14580	COG2116	formate transmembrane transporter activity
AD867_14590	COG0628	permease
AD867_14595	COG4783	chaperone-mediated protein folding
AD867_14600	COG1393	Belongs to the ArsC family
AD867_14610	COG2233	PERMEase
AD867_14625	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AD867_14630	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AD867_14635	COG0248	Ppx GppA phosphatase
AD867_14670	COG3133	Outer membrane lipoprotein
AD867_14685	COG0517	IMP dehydrogenase activity
AD867_14685	COG0516	GMP reductase activity
AD867_14695	COG1645	bacterial-type flagellum-dependent swarming motility
AD867_14710	COG2976	Protein conserved in bacteria
AD867_14740	COG4953	penicillin-binding protein 1C
AD867_14745	COG3547	Transposase (IS116 IS110 IS902 family)
AD867_14765	COG2975	iron-sulfur cluster assembly
AD867_14770	COG0633	Ferredoxin
AD867_14790	COG0822	iron-sulfur transferase activity
AD867_14810	COG0483	inositol monophosphate 1-phosphatase activity
AD867_14815	COG1073	alpha beta
AD867_14820	COG3711	transcriptional antiterminator
AD867_14825	COG2814	Major facilitator Superfamily
AD867_14830	COG0583	DNA-binding transcription factor activity
AD867_14860	COG2259	Doxx family
AD867_14865	COG2017	converts alpha-aldose to the beta-anomer
AD867_14870	COG1063	alcohol dehydrogenase
AD867_14875	COG1172	Belongs to the binding-protein-dependent transport system permease family
AD867_14880	COG1129	ABC transporter
AD867_14890	COG0457	Tetratricopeptide repeat
AD867_14895	COG1940	carbohydrate kinase activity
AD867_14910	COG0347	Belongs to the P(II) protein family
AD867_14915	COG2204	response regulator
AD867_14920	COG3170	Tfp pilus assembly protein FimV
AD867_14925	COG2205	protein histidine kinase activity
AD867_14930	COG0047	phosphoribosylformylglycinamidine synthase activity
AD867_14930	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AD867_14940	COG0590	tRNA wobble adenosine to inosine editing
AD867_14945	COG0560	Phosphoserine phosphatase
AD867_14950	COG1737	Transcriptional regulator
AD867_14975	COG5301	cellulose 1,4-beta-cellobiosidase activity
AD867_14990	COG2963	transposase activity
AD867_15000	COG4771	TonB-dependent receptor
AD867_15035	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AD867_15080	COG0681	Belongs to the peptidase S26 family
AD867_15090	COG3086	response to oxidative stress
AD867_15095	COG3026	antisigma factor binding
AD867_15100	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AD867_15105	COG1595	DNA-templated transcription, initiation
AD867_15125	COG0513	Belongs to the DEAD box helicase family
AD867_15130	COG0583	DNA-binding transcription factor activity
AD867_15150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AD867_15160	COG3118	belongs to the thioredoxin family
AD867_15170	COG1042	CoA-binding domain protein
AD867_15170	COG0045	succinate-CoA ligase (ADP-forming) activity
AD867_15170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AD867_15175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AD867_15180	COG5544	Lipoprotein
AD867_15185	COG0477	Major facilitator Superfamily
AD867_15210	COG3385	transposase activity
AD867_15215	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AD867_15220	COG0564	pseudouridine synthase activity
AD867_15230	COG0542	response to heat
AD867_15235	COG3385	transposase activity
AD867_15240	COG3385	transposase activity
AD867_15250	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AD867_15255	COG1605	Chorismate mutase
AD867_15255	COG0077	Prephenate dehydratase
AD867_15260	COG0287	Prephenate dehydrogenase
AD867_15260	COG1605	Chorismate mutase
AD867_15265	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AD867_15285	COG2885	chlorophyll binding
AD867_15310	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AD867_15315	COG4137	Cytochrome C assembly protein
AD867_15320	COG4536	flavin adenine dinucleotide binding
AD867_15335	COG0497	DNA recombination
AD867_15340	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AD867_15350	COG2867	negative regulation of translational initiation
AD867_15360	COG0582	viral genome integration into host DNA
AD867_15365	COG3677	Transposase
AD867_15375	COG2963	transposase activity
AD867_15380	COG2801	Transposase and inactivated derivatives
AD867_15395	COG0366	Alpha amylase catalytic
AD867_15405	COG0579	oxidoreductase
AD867_15420	COG1113	amino acid transport
AD867_15425	COG1802	Transcriptional regulator
AD867_15430	COG1652	LysM domain
AD867_15435	COG0401	homolog of Blt101
AD867_15445	COG2963	transposase activity
AD867_15450	COG0640	Transcriptional regulator
AD867_15455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AD867_15460	COG2916	Histone family protein nucleoid-structuring protein H-NS
AD867_15475	COG4575	ribosome binding
AD867_15480	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AD867_15485	COG1780	Probably involved in ribonucleotide reductase function
AD867_15490	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AD867_15495	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AD867_15500	COG4175	Glycine betaine
AD867_15505	COG4176	ABC-type proline glycine betaine transport system permease component
AD867_15510	COG2113	Glycine betaine
AD867_15515	COG2814	Major facilitator Superfamily
AD867_15520	COG2814	Major facilitator Superfamily
AD867_15525	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AD867_15535	COG1846	Transcriptional regulator
AD867_15545	COG2814	Major facilitator Superfamily
AD867_15560	COG1238	metal cluster binding
AD867_15565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AD867_15620	COG1546	Belongs to the CinA family
AD867_15625	COG2951	lytic endotransglycosylase activity
AD867_15635	COG3732	PTS system glucitol sorbitol-specific
AD867_15645	COG1028	Short-chain dehydrogenase reductase Sdr
AD867_15650	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AD867_15655	COG1349	DNA-binding transcription factor activity
AD867_15680	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AD867_15685	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AD867_15690	COG1609	Transcriptional regulator
AD867_15695	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AD867_15700	COG3261	NADH dehydrogenase
AD867_15700	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AD867_15705	COG0650	Formate hydrogenlyase subunit 4
AD867_15710	COG0651	ATP synthesis coupled electron transport
AD867_15715	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AD867_15730	COG0375	protein maturation
AD867_15735	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AD867_15740	COG0298	carbon dioxide binding
AD867_15745	COG0409	Hydrogenase expression formation protein
AD867_15750	COG0309	Hydrogenase expression formation protein (HypE)
AD867_15755	COG3604	Transcriptional regulator
AD867_15770	COG3677	Transposase
AD867_15790	COG1349	DNA-binding transcription factor activity
AD867_15800	COG3395	kinase activity
AD867_15830	COG3423	Transcriptional regulator
AD867_15860	COG4942	peptidase
AD867_15860	COG1388	LysM domain
AD867_15915	COG2234	aminopeptidase activity
AD867_15945	COG0720	synthase
AD867_15950	COG0644	oxidoreductase
AD867_15955	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AD867_15965	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AD867_15970	COG2086	electron transfer activity
AD867_15975	COG0477	Major facilitator Superfamily
AD867_15980	COG0277	FAD linked oxidase domain protein
AD867_15985	COG1662	PFAM IS1 transposase
AD867_15990	COG0602	queuosine metabolic process
AD867_16000	COG3677	Transposase
AD867_16025	COG3956	TIGRFAM MazG family protein
AD867_16030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AD867_16045	COG4948	Mandelate Racemase Muconate Lactonizing
AD867_16050	COG4948	Mandelate Racemase Muconate Lactonizing
AD867_16055	COG2271	Major facilitator Superfamily
AD867_16060	COG0716	FMN binding
AD867_16065	COG0564	pseudouridine synthase activity
AD867_16070	COG3098	single-species biofilm formation
AD867_16090	COG1611	Belongs to the LOG family
AD867_16095	COG3385	transposase activity
AD867_16100	COG0814	amino acid
AD867_16105	COG1760	l-serine dehydratase
AD867_16115	COG1454	alcohol dehydrogenase
AD867_16120	COG0235	Class ii aldolase
AD867_16125	COG0738	Major facilitator superfamily
AD867_16135	COG1070	Carbohydrate kinase
AD867_16150	COG1349	DNA-binding transcription factor activity
AD867_16160	COG2363	Small membrane protein
AD867_16165	COG0583	DNA-binding transcription factor activity
AD867_16175	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AD867_16180	COG2166	iron-sulfur cluster assembly
AD867_16185	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AD867_16190	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AD867_16205	COG0860	N-Acetylmuramoyl-L-alanine amidase
AD867_16215	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AD867_16220	COG1074	ATP-dependent DNA helicase activity
AD867_16230	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AD867_16235	COG4967	type IV pilus modification protein PilV
AD867_16245	COG4795	General secretion pathway protein
AD867_16265	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AD867_16290	COG0861	Integral membrane protein TerC family
AD867_16300	COG0667	Aldo Keto reductase
AD867_16315	COG1609	Transcriptional regulator
AD867_16320	COG0019	diaminopimelate decarboxylase activity
AD867_16325	COG0583	DNA-binding transcription factor activity
AD867_16330	COG1794	racemase activity, acting on amino acids and derivatives
AD867_16335	COG2814	Major facilitator Superfamily
AD867_16340	COG1028	Short-chain dehydrogenase reductase Sdr
AD867_16350	COG0183	Belongs to the thiolase family
AD867_16355	COG0814	amino acid
AD867_16360	COG2963	transposase activity
AD867_16365	COG2801	Transposase and inactivated derivatives
AD867_16370	COG3387	PFAM Glycoside hydrolase 15-related
AD867_16390	COG3344	reverse transcriptase
AD867_16395	COG2801	Transposase and inactivated derivatives
AD867_16425	COG4942	peptidase
AD867_16435	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AD867_16440	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AD867_16445	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AD867_16450	COG2080	2 iron, 2 sulfur cluster binding
AD867_16455	COG3677	Transposase
AD867_16465	COG2963	transposase activity
AD867_16475	COG2233	PERMEase
AD867_16500	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AD867_16505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AD867_16515	COG0716	FMN binding
AD867_16535	COG1272	protein, Hemolysin III
AD867_16545	COG2723	6-phospho-beta-galactosidase activity
AD867_16550	COG1028	Short-chain dehydrogenase reductase Sdr
AD867_16570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AD867_16575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AD867_16580	COG0006	proline dipeptidase activity
AD867_16595	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AD867_16605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AD867_16620	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AD867_16620	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AD867_16625	COG1703	isobutyryl-CoA mutase activity
AD867_16630	COG1024	Enoyl-CoA hydratase
AD867_16640	COG0583	DNA-binding transcription factor activity
AD867_16645	COG2968	Membrane
AD867_16650	COG1279	arginine transmembrane transporter activity
AD867_16655	COG0668	transmembrane transport
AD867_16660	COG0191	fructose-bisphosphate aldolase activity
AD867_16690	COG1122	ATPase activity
AD867_16695	COG1122	ATPase activity
AD867_16700	COG1072	(Pantothenic acid kinase))
AD867_16710	COG1494	fructose-1,6-bisphosphatase
AD867_16715	COG1063	alcohol dehydrogenase
AD867_16725	COG3677	Transposase
AD867_16730	COG0330	HflC and HflK could
AD867_16735	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AD867_16740	COG0501	Belongs to the peptidase M48B family
AD867_16755	COG1662	PFAM IS1 transposase
AD867_16760	COG3677	Transposase
AD867_16790	COG2814	Major facilitator Superfamily
AD867_16800	COG2356	endonuclease I
AD867_16805	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AD867_16825	COG2805	Type II/IV secretion system protein
AD867_16830	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AD867_16835	COG0762	integral membrane protein
AD867_16850	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AD867_16860	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AD867_16870	COG3677	Transposase
AD867_16885	COG0252	asparaginase activity
AD867_16900	COG3171	Protein conserved in bacteria
AD867_16910	COG1194	a g-specific adenine glycosylase
AD867_16925	COG2211	Major facilitator Superfamily
AD867_16930	COG1982	Orn Lys Arg decarboxylase major
AD867_16935	COG1811	Na channel or pump
AD867_16945	COG0582	viral genome integration into host DNA
AD867_16950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AD867_16950	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AD867_16955	COG4372	Transposase
AD867_16970	COG3468	outer membrane autotransporter barrel domain protein
AD867_16980	COG4372	Transposase
AD867_16995	COG3328	transposase activity
AD867_17010	COG3344	reverse transcriptase
AD867_17050	COG2963	transposase activity
AD867_17090	COG3468	outer membrane autotransporter barrel domain protein
AD867_17095	COG2020	methyltransferase activity
AD867_17125	COG2003	Belongs to the UPF0758 family
AD867_17165	COG2963	transposase activity
AD867_17170	COG2801	Transposase and inactivated derivatives
AD867_17200	COG1620	l-lactate permease
AD867_17210	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AD867_17220	COG0277	FAD linked oxidase domain protein
AD867_17225	COG0277	FAD linked oxidase domain protein
AD867_17230	COG0277	FAD linked oxidase domain protein
AD867_17235	COG2186	Transcriptional regulator
AD867_17245	COG0318	PFAM AMP-dependent synthetase and ligase
AD867_17255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AD867_17270	COG0795	lipopolysaccharide-transporting ATPase activity
AD867_17275	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AD867_17285	COG2244	polysaccharide biosynthetic process
AD867_17290	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AD867_17295	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AD867_17300	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AD867_17305	COG0306	phosphate transporter
AD867_17310	COG0754	glutathionylspermidine amidase activity
AD867_17315	COG0625	glutathione transferase activity
AD867_17320	COG0298	carbon dioxide binding
AD867_17325	COG0375	protein maturation
AD867_17330	COG1773	rubredoxin
AD867_17335	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AD867_17340	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AD867_17345	COG5557	Pfam Polysulphide reductase, NrfD
AD867_17350	COG0437	4 iron, 4 sulfur cluster binding
AD867_17355	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AD867_17385	COG1028	Short-chain dehydrogenase reductase Sdr
AD867_17390	COG0848	biopolymer transport protein
AD867_17395	COG0811	peptide transport
AD867_17405	COG0626	cystathionine gamma-synthase activity
AD867_17410	COG0586	Pfam SNARE associated Golgi protein
AD867_17415	COG2207	Transcriptional regulator
AD867_17425	COG1979	alcohol dehydrogenase
AD867_17430	COG0656	L-ascorbic acid biosynthetic process
AD867_17440	COG4238	major outer membrane lipoprotein
AD867_17450	COG2132	Multicopper oxidase
AD867_17455	COG0204	Acyl-transferase
AD867_17460	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AD867_17470	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AD867_17475	COG3111	PFAM Bacterial OB fold (BOF) protein
AD867_17480	COG0745	RESPONSE REGULATOR receiver
AD867_17485	COG0642	Histidine kinase
AD867_17495	COG2249	NAD(P)H dehydrogenase (quinone) activity
AD867_17500	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AD867_17505	COG0187	DNA topoisomerase II activity
AD867_17510	COG3150	esterase
AD867_17515	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AD867_17520	COG3151	Protein conserved in bacteria
AD867_17525	COG0494	nUDIX hydrolase
AD867_17530	COG1538	Outer membrane efflux protein
AD867_17545	COG0754	glutathionylspermidine amidase activity
AD867_17550	COG3384	dioxygenase
AD867_17570	COG2960	long-chain fatty acid transporting porin activity
AD867_17575	COG2963	transposase activity
AD867_17605	COG1662	PFAM IS1 transposase
AD867_17635	COG3025	triphosphatase activity
AD867_17645	COG4991	sh3 domain protein
AD867_17660	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AD867_17670	COG0583	DNA-binding transcription factor activity
AD867_17700	COG0358	DNA primase activity
AD867_17705	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AD867_17710	COG3385	transposase activity
AD867_17730	COG1695	Transcriptional regulator
AD867_17750	COG1609	Transcriptional regulator
AD867_17755	COG3250	beta-galactosidase activity
AD867_17760	COG2731	YhcH YjgK YiaL family protein
AD867_17765	COG0531	amino acid
AD867_17775	COG3408	Glycogen debranching enzyme
AD867_17775	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AD867_17780	COG1902	pentaerythritol trinitrate reductase activity
AD867_17780	COG0446	pyridine nucleotide-disulphide oxidoreductase
AD867_17785	COG5499	transcription regulator containing HTH domain
AD867_17790	COG4680	protein conserved in bacteria
AD867_17805	COG1451	nucleotide metabolic process
AD867_17810	COG2949	membrane
AD867_17815	COG0673	inositol 2-dehydrogenase activity
AD867_17820	COG0861	Integral membrane protein TerC family
AD867_17835	COG2721	sulfolactate sulfo-lyase activity
AD867_17845	COG2271	Major facilitator Superfamily
AD867_17860	COG1662	PFAM IS1 transposase
AD867_17865	COG2186	Transcriptional regulator
AD867_17870	COG0586	Pfam SNARE associated Golgi protein
AD867_17880	COG1422	Protein of unknown function (DUF1090)
AD867_17885	COG4575	ribosome binding
AD867_17890	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AD867_17900	COG2259	Doxx family
AD867_17905	COG0435	Glutathione S-transferase
AD867_17910	COG3152	Membrane
AD867_17915	COG0583	DNA-binding transcription factor activity
AD867_17920	COG1741	Belongs to the pirin family
AD867_17935	COG0814	amino acid
AD867_17940	COG1760	l-serine dehydratase
AD867_17945	COG0251	oxidation-reduction process
AD867_17950	COG1882	Formate acetyltransferase
AD867_17955	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AD867_17965	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AD867_17970	COG0583	DNA-binding transcription factor activity
AD867_17990	COG1929	Belongs to the glycerate kinase type-1 family
AD867_17995	COG2084	Dehydrogenase
AD867_18010	COG2271	Major facilitator Superfamily
AD867_18015	COG2721	sulfolactate sulfo-lyase activity
AD867_18020	COG1349	DNA-binding transcription factor activity
AD867_18030	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AD867_18040	COG3716	PTS system mannose fructose sorbose family IID component
AD867_18045	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AD867_18055	COG1662	PFAM IS1 transposase
AD867_18065	COG3715	PTS system
AD867_18070	COG3716	PTS system mannose fructose sorbose family IID component
AD867_18075	COG0363	glucosamine-6-phosphate deaminase activity
AD867_18090	COG3539	Fimbrial protein
AD867_18095	COG3121	Chaperone
AD867_18115	COG2963	transposase activity
AD867_18125	COG3539	Fimbrial protein
AD867_18130	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AD867_18145	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AD867_18150	COG2823	Periplasmic or secreted lipoprotein
AD867_18155	COG0701	Predicted permease
AD867_18160	COG0702	epimerase
AD867_18165	COG0693	protein deglycase activity
AD867_18180	COG3153	acetyltransferase
AD867_18200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AD867_18205	COG0814	amino acid
AD867_18215	COG0513	Belongs to the DEAD box helicase family
AD867_18220	COG4785	May be involved in cell division
AD867_18250	COG0195	Participates in both transcription termination and antitermination
AD867_18280	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AD867_18290	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AD867_18295	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AD867_18305	COG1534	Rna-binding protein
AD867_18310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AD867_18315	COG2027	D-alanyl-D-alanine carboxypeptidase
AD867_18325	COG0697	spore germination
AD867_18340	COG0142	geranyltranstransferase activity
AD867_18345	COG3423	Transcriptional regulator
AD867_18355	COG5007	Belongs to the BolA IbaG family
AD867_18360	COG3113	response to antibiotic
AD867_18365	COG2854	intermembrane phospholipid transfer
AD867_18370	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AD867_18375	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AD867_18380	COG1127	ABC transporter
AD867_18385	COG0530	calcium, potassium:sodium antiporter activity
AD867_18395	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AD867_18400	COG3117	lipopolysaccharide transmembrane transporter activity
AD867_18405	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AD867_18410	COG1137	ATPase activity
AD867_18415	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AD867_18420	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AD867_18425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AD867_18435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AD867_18440	COG0515	serine threonine protein kinase
AD867_18450	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AD867_18455	COG0784	Response regulator, receiver
AD867_18455	COG2198	Histidine kinase
AD867_18455	COG5002	protein histidine kinase activity
AD867_18460	COG1242	4 iron, 4 sulfur cluster binding
AD867_18465	COG0067	glutamate synthase
AD867_18465	COG0069	glutamate synthase activity
AD867_18465	COG0070	glutamate synthase
AD867_18470	COG0493	'glutamate synthase
AD867_18495	COG2731	YhcH YjgK YiaL family protein
AD867_18530	COG1662	PFAM IS1 transposase
AD867_18535	COG3069	C4-dicarboxylate transmembrane transporter activity
AD867_18540	COG2969	positive regulation of protein catabolic process
AD867_18545	COG0625	glutathione transferase activity
AD867_18560	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AD867_18565	COG3105	Protein conserved in bacteria
AD867_18575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AD867_18595	COG2732	(Barnase) inhibitor
AD867_18615	COG0583	DNA-binding transcription factor activity
AD867_18620	COG0312	modulator of DNA gyrase
AD867_18625	COG3164	Protein of unknown function
AD867_18630	COG1530	ribonuclease E activity
AD867_18640	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AD867_18645	COG1792	Involved in formation and maintenance of cell shape
AD867_18650	COG1077	Cell shape determining protein MreB Mrl
AD867_18660	COG2200	EAL domain
AD867_18660	COG2199	diguanylate cyclase activity
AD867_18665	COG0604	alcohol dehydrogenase
AD867_18685	COG0511	ligase activity, forming carbon-carbon bonds
AD867_18690	COG0439	Biotin carboxylase
AD867_18695	COG3924	membrane
AD867_18700	COG4145	pantothenate transmembrane transporter activity
AD867_18720	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AD867_18730	COG3677	Transposase
AD867_18730	COG1662	PFAM IS1 transposase
AD867_18740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AD867_18755	COG3677	Transposase
AD867_18765	COG0765	amino acid transport
AD867_18770	COG1126	abc transporter atp-binding protein
AD867_18810	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AD867_18830	COG0551	DNA topoisomerase type I activity
AD867_18840	COG0758	DNA mediated transformation
AD867_18860	COG0569	domain protein
AD867_18870	COG3436	PFAM IS66 Orf2 family protein
AD867_18875	COG4372	Transposase
AD867_18905	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AD867_18915	COG0201	protein transport
AD867_19005	COG0089	rRNA binding
AD867_19040	COG2906	2 iron, 2 sulfur cluster binding
AD867_19080	COG2964	Protein conserved in bacteria
AD867_19085	COG0545	Peptidyl-prolyl cis-trans isomerase
AD867_19095	COG1047	Peptidyl-prolyl cis-trans
AD867_19100	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AD867_19115	COG0488	(ABC) transporter
AD867_19120	COG0429	hydrolase of the alpha beta-hydrolase fold
AD867_19130	COG3954	Phosphoribulokinase
AD867_19135	COG1765	OsmC-like protein
AD867_19145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AD867_19150	COG1289	transmembrane transporter activity
AD867_19160	COG0512	Glutamine amidotransferase of anthranilate synthase
AD867_19165	COG2184	nucleotidyltransferase activity
AD867_19175	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AD867_19185	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AD867_19190	COG2146	nitrite reductase [NAD(P)H] activity
AD867_19195	COG2116	formate transmembrane transporter activity
AD867_19215	COG2222	sugar isomerase
AD867_19235	COG0626	cystathionine gamma-synthase activity
AD867_19250	COG1735	metal-dependent hydrolase with the TIM-barrel fold
AD867_19255	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AD867_19260	COG3457	Alanine racemase
AD867_19270	COG2188	Transcriptional regulator
AD867_19285	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AD867_19290	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AD867_19295	COG3266	domain, Protein
AD867_19310	COG4796	Type ii and iii secretion system protein
AD867_19325	COG3166	PFAM Fimbrial assembly family protein
AD867_19330	COG4972	Pilus assembly protein
AD867_19335	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AD867_19340	COG0494	nUDIX hydrolase
AD867_19350	COG1011	Hydrolase
AD867_19355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AD867_19365	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AD867_19380	COG2205	protein histidine kinase activity
AD867_19385	COG0745	RESPONSE REGULATOR receiver
AD867_19390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AD867_19395	COG2183	response to ionizing radiation
AD867_19400	COG1918	ferrous iron import across plasma membrane
AD867_19415	COG5464	transposase or invertase
AD867_19420	COG2963	transposase activity
AD867_19455	COG2610	gluconate transmembrane transporter activity
AD867_19460	COG1640	4-alpha-glucanotransferase
AD867_19465	COG0058	SHG alpha-glucan phosphorylase activity
AD867_19485	COG1690	Belongs to the RtcB family
AD867_19490	COG4650	regulator
AD867_19495	COG1349	DNA-binding transcription factor activity
AD867_19510	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AD867_19515	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AD867_19520	COG3385	transposase activity
AD867_19525	COG0058	SHG alpha-glucan phosphorylase activity
AD867_19550	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AD867_19555	COG2095	MarC family integral membrane protein
AD867_19560	COG2610	gluconate transmembrane transporter activity
AD867_19565	COG3265	gluconokinase activity
AD867_19570	COG1609	Transcriptional regulator
AD867_19575	COG1741	Belongs to the pirin family
AD867_19580	COG0673	inositol 2-dehydrogenase activity
AD867_19585	COG1247	-acetyltransferase
AD867_19590	COG0405	Gamma-glutamyltransferase
AD867_19600	COG0584	glycerophosphoryl diester phosphodiesterase
AD867_19610	COG0395	ABC-type sugar transport system, permease component
AD867_19630	COG0410	ABC transporter
AD867_19635	COG0411	ABC transporter
AD867_19640	COG4177	L-phenylalanine transmembrane transporter activity
AD867_19645	COG0559	Belongs to the binding-protein-dependent transport system permease family
AD867_19650	COG0683	leucine binding
AD867_19655	COG0456	acetyltransferase
AD867_19665	COG0683	leucine binding
AD867_19670	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AD867_19675	COG2177	Part of the ABC transporter FtsEX involved in
AD867_19680	COG2884	Cell division ATP-binding protein ftsE
AD867_19685	COG0552	protein localization to endoplasmic reticulum
AD867_19690	COG0742	ribosomal rna small subunit methyltransferase
AD867_19695	COG3776	membrane
AD867_19705	COG3714	YhhN family
AD867_19720	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AD867_19735	COG0628	permease
AD867_19740	COG2091	lysine biosynthetic process via aminoadipic acid
AD867_19745	COG0747	negative chemotaxis
AD867_19750	COG0601	transmembrane transport
AD867_19755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AD867_19785	COG0842	Transport permease protein
AD867_19790	COG1129	ABC transporter
AD867_19790	COG0842	Transport permease protein
AD867_19795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AD867_19850	COG2963	transposase activity
AD867_19895	COG2081	HI0933 family
AD867_19900	COG0306	phosphate transporter
AD867_19910	COG0589	response to stress
AD867_19925	COG0339	signal peptide processing
AD867_19930	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AD867_19935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AD867_19955	COG3677	Transposase
AD867_19960	COG1393	Belongs to the ArsC family
AD867_19965	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AD867_19970	COG0640	Transcriptional regulator
AD867_19975	COG3677	Transposase
AD867_19995	COG3065	identical protein binding
AD867_20020	COG3247	response to pH
AD867_20025	COG2771	luxR family
AD867_20035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AD867_20045	COG3677	Transposase
AD867_20055	COG3385	transposase activity
AD867_20060	COG2197	response regulator
AD867_20065	COG0583	DNA-binding transcription factor activity
AD867_20070	COG1295	ribonuclease BN
AD867_20075	COG0477	Major facilitator Superfamily
AD867_20080	COG2982	Protein involved in outer membrane biogenesis
AD867_20085	COG2200	EAL domain
AD867_20100	COG0612	Peptidase, M16
AD867_20110	COG2200	EAL domain
AD867_20110	COG2199	diguanylate cyclase activity
AD867_20115	COG3118	belongs to the thioredoxin family
AD867_20115	COG0457	Tetratricopeptide repeat
AD867_20120	COG3118	belongs to the thioredoxin family
AD867_20120	COG0457	Tetratricopeptide repeat
AD867_20125	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AD867_20130	COG1215	transferase activity, transferring glycosyl groups
AD867_20140	COG1215	transferase activity, transferring glycosyl groups
AD867_20165	COG2194	sulfuric ester hydrolase activity
AD867_20195	COG0814	amino acid
AD867_20200	COG4608	Belongs to the ABC transporter superfamily
AD867_20205	COG0444	Belongs to the ABC transporter superfamily
AD867_20210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AD867_20215	COG0601	transmembrane transport
AD867_20225	COG0747	negative chemotaxis
AD867_20235	COG2194	sulfuric ester hydrolase activity
AD867_20240	COG2223	nitrite transmembrane transporter activity
AD867_20245	COG5571	outer membrane autotransporter
AD867_20250	COG2818	Glycosylase
AD867_20255	COG0456	acetyltransferase
AD867_20260	COG0243	molybdopterin cofactor binding
AD867_20265	COG2885	chlorophyll binding
AD867_20285	COG1278	Cold shock
AD867_20295	COG2801	Transposase and inactivated derivatives
AD867_20300	COG2963	transposase activity
AD867_20305	COG1662	PFAM IS1 transposase
AD867_20310	COG1858	cytochrome C peroxidase
AD867_20325	COG2207	Transcriptional regulator
AD867_20335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AD867_20340	COG1662	PFAM IS1 transposase
AD867_20360	COG3274	enterobacterial common antigen metabolic process
AD867_20365	COG4682	membrane
AD867_20370	COG4682	membrane
AD867_20375	COG1070	Carbohydrate kinase
AD867_20385	COG4213	ABC transporter substrate-binding protein
AD867_20395	COG4214	carbohydrate transport
AD867_20405	COG2992	FlgJ-related protein
AD867_20410	COG0366	Alpha amylase catalytic
AD867_20415	COG3977	Valine--pyruvate aminotransferase
AD867_20425	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AD867_20430	COG1414	Transcriptional regulator
AD867_20440	COG2731	YhcH YjgK YiaL family protein
AD867_20445	COG3677	Transposase
AD867_20455	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AD867_20460	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AD867_20465	COG1662	PFAM IS1 transposase
AD867_20480	COG1012	belongs to the aldehyde dehydrogenase family
AD867_20485	COG1454	alcohol dehydrogenase
AD867_20490	COG3276	selenocysteine insertion sequence binding
AD867_20500	COG0625	glutathione transferase activity
AD867_20505	COG1566	PFAM secretion protein HlyD family protein
AD867_20515	COG2213	PTS system mannitol-specific
AD867_20515	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AD867_20525	COG3722	fumarate hydratase activity
AD867_20540	COG1662	PFAM IS1 transposase
AD867_20555	COG1620	l-lactate permease
AD867_20560	COG2186	Transcriptional regulator
AD867_20570	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AD867_20575	COG1045	serine acetyltransferase
AD867_20590	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AD867_20595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AD867_20605	COG4942	peptidase
AD867_20610	COG2861	carbohydrate metabolic process
AD867_20620	COG3677	Transposase
AD867_20630	COG0156	8-amino-7-oxononanoate synthase activity
AD867_20645	COG0859	PFAM glycosyl transferase family 9
AD867_20650	COG0859	PFAM glycosyl transferase family 9
AD867_20670	COG3642	lipopolysaccharide core region biosynthetic process
AD867_20680	COG0515	serine threonine protein kinase
AD867_20685	COG0438	transferase activity, transferring glycosyl groups
AD867_20690	COG0859	PFAM glycosyl transferase family 9
AD867_20700	COG3677	Transposase
AD867_20705	COG1519	Transferase
AD867_20735	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AD867_20760	COG1561	YicC-like family, N-terminal region
AD867_20765	COG3645	SOS response
AD867_20770	COG2860	membrane
AD867_20790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AD867_20795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AD867_20800	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AD867_20805	COG0786	glutamate:sodium symporter activity
AD867_20810	COG2233	PERMEase
AD867_20815	COG2982	Protein involved in outer membrane biogenesis
AD867_20820	COG1501	Belongs to the glycosyl hydrolase 31 family
AD867_20835	COG0582	viral genome integration into host DNA
AD867_20850	COG2801	Transposase and inactivated derivatives
AD867_20860	COG2963	transposase activity
AD867_20895	COG2963	transposase activity
AD867_20910	COG2801	Transposase and inactivated derivatives
AD867_20920	COG1662	PFAM IS1 transposase
AD867_20960	COG3468	outer membrane autotransporter barrel domain protein
AD867_20970	COG2963	transposase activity
AD867_20975	COG3188	usher protein
AD867_20985	COG3677	Transposase
AD867_20995	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AD867_21000	COG0573	inorganic phosphate transmembrane transporter activity
AD867_21005	COG0581	inorganic phosphate transmembrane transporter activity
AD867_21010	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AD867_21015	COG0704	Plays a role in the regulation of phosphate uptake
AD867_21020	COG3711	transcriptional antiterminator
AD867_21025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AD867_21025	COG1263	PTS System
AD867_21025	COG2190	(PTS) system
AD867_21030	COG2723	6-phospho-beta-galactosidase activity
AD867_21035	COG3677	Transposase
AD867_21045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AD867_21050	COG2252	PERMEase
AD867_21055	COG0431	NADPH-dependent FMN reductase
AD867_21060	COG2091	lysine biosynthetic process via aminoadipic acid
AD867_21090	COG0814	amino acid
AD867_21105	COG3677	Transposase
AD867_21145	COG0592	DNA-directed DNA polymerase activity
AD867_21155	COG0187	DNA topoisomerase II activity
AD867_21165	COG3753	Protein conserved in bacteria
AD867_21170	COG0561	phosphatase activity
AD867_21180	COG2186	Transcriptional regulator
AD867_21185	COG3734	2-keto-3-deoxy-galactonokinase
AD867_21190	COG0800	Aldolase
AD867_21205	COG2271	Major facilitator Superfamily
AD867_21215	COG0823	Involved in the tonB-independent uptake of proteins
AD867_21220	COG5645	(Lipo)protein
AD867_21245	COG2188	Transcriptional regulator
AD867_21260	COG2207	Transcriptional regulator
AD867_21265	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AD867_21270	COG3119	arylsulfatase activity
AD867_21275	COG3119	arylsulfatase activity
AD867_21285	COG2149	membrane
AD867_21295	COG0641	radical SAM
AD867_21300	COG2814	Major facilitator Superfamily
AD867_21325	COG0028	Belongs to the TPP enzyme family
AD867_21330	COG0440	acetolactate synthase activity
AD867_21335	COG2197	response regulator
AD867_21340	COG3851	Histidine kinase
AD867_21345	COG2271	Major facilitator Superfamily
AD867_21350	COG2271	Major facilitator Superfamily
AD867_21360	COG2252	PERMEase
AD867_21400	COG2963	transposase activity
AD867_21420	COG3385	transposase activity
AD867_21545	COG3312	ion transport
AD867_21560	COG0716	FMN binding
AD867_21565	COG1522	sequence-specific DNA binding
AD867_21585	COG3385	transposase activity
AD867_21600	COG1129	ABC transporter
AD867_21605	COG1662	PFAM IS1 transposase
AD867_21615	COG1172	Belongs to the binding-protein-dependent transport system permease family
AD867_21625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AD867_21630	COG1609	Transcriptional regulator
AD867_21635	COG0477	Major facilitator Superfamily
AD867_21640	COG2186	Transcriptional regulator
AD867_21680	COG3085	chromosome segregation
AD867_21700	COG3978	acetolactate synthase activity
AD867_21705	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AD867_21715	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AD867_21720	COG0583	DNA-binding transcription factor activity
AD867_21730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AD867_21735	COG0210	DNA helicase
AD867_21750	COG3118	belongs to the thioredoxin family
AD867_21760	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AD867_21770	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AD867_21775	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AD867_21780	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AD867_21785	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AD867_21790	COG1088	dTDP-glucose 4,6-dehydratase activity
AD867_21795	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AD867_21800	COG0456	acetyltransferase
AD867_21805	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AD867_21810	COG2244	polysaccharide biosynthetic process
AD867_21830	COG1113	amino acid transport
AD867_21855	COG0641	radical SAM
AD867_21870	COG3071	HemY protein
AD867_21875	COG2959	enzyme of heme biosynthesis
AD867_21880	COG1587	Uroporphyrinogen-III synthase
AD867_21900	COG3677	Transposase
AD867_21900	COG1662	PFAM IS1 transposase
AD867_21915	COG5567	small periplasmic lipoprotein
AD867_21925	COG3159	Protein conserved in bacteria
AD867_21935	COG1011	Hydrolase
AD867_21940	COG0210	DNA helicase
AD867_21950	COG3385	transposase activity
AD867_21965	COG0598	Magnesium transport protein CorA
AD867_21980	COG2962	Rard protein
AD867_21985	COG2050	protein possibly involved in aromatic compounds catabolism
AD867_21990	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AD867_21995	COG0514	ATP-dependent DNA helicase (RecQ)
AD867_22000	COG1280	lysine exporter protein (LysE YggA)
AD867_22005	COG1280	lysine exporter protein (LysE YggA)
AD867_22010	COG2267	carboxylic ester hydrolase activity
AD867_22015	COG0561	phosphatase activity
AD867_22025	COG0583	DNA-binding transcription factor activity
AD867_22035	COG0412	Dienelactone hydrolase
AD867_22040	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AD867_22045	COG1322	Protein conserved in bacteria
AD867_22055	COG3165	ubiquinone biosynthetic process from chorismate
AD867_22065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AD867_22070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AD867_22075	COG0805	protein transport
AD867_22085	COG0250	Participates in transcription elongation, termination and antitermination
AD867_22095	COG0543	2 iron, 2 sulfur cluster binding
AD867_22115	COG1739	Uncharacterized protein family UPF0029
AD867_22120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AD867_22125	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AD867_22155	COG1763	Mo-molybdopterin cofactor biosynthetic process
AD867_22160	COG0746	molybdenum cofactor guanylyltransferase activity
AD867_22165	COG3084	Protein conserved in bacteria
AD867_22180	COG5339	Protein conserved in bacteria
AD867_22185	COG0204	Acyl-transferase
AD867_22195	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AD867_22195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AD867_22210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AD867_22220	COG2204	response regulator
AD867_22225	COG3852	Histidine kinase
AD867_22230	COG0174	glutamine synthetase
AD867_22245	COG2188	Transcriptional regulator
AD867_22250	COG1082	Xylose isomerase domain protein TIM barrel
AD867_22260	COG3677	Transposase
AD867_22275	COG2211	Major facilitator Superfamily
AD867_22285	COG1501	Belongs to the glycosyl hydrolase 31 family
AD867_22290	COG2017	converts alpha-aldose to the beta-anomer
AD867_22295	COG2942	2-epimerase
AD867_22305	COG2084	Dehydrogenase
AD867_22310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AD867_22315	COG1349	DNA-binding transcription factor activity
AD867_22320	COG1011	Hydrolase
AD867_22335	COG0456	acetyltransferase
AD867_22345	COG3677	Transposase
AD867_22355	COG3677	Transposase
AD867_22365	COG3677	Transposase
AD867_22390	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AD867_22395	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AD867_22410	COG2864	formate dehydrogenase
AD867_22415	COG0437	4 iron, 4 sulfur cluster binding
AD867_22420	COG0243	molybdopterin cofactor binding
AD867_22420	COG3383	formate dehydrogenase (NAD+) activity
AD867_22425	COG3383	formate dehydrogenase (NAD+) activity
AD867_22425	COG0243	molybdopterin cofactor binding
AD867_22440	COG3677	Transposase
AD867_22445	COG3711	transcriptional antiterminator
AD867_22445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AD867_22450	COG1363	Peptidase, m42
AD867_22455	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AD867_22455	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AD867_22460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AD867_22505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AD867_22525	COG2963	transposase activity
AD867_22530	COG2258	MOSC domain
AD867_22535	COG2205	protein histidine kinase activity
AD867_22540	COG0745	RESPONSE REGULATOR receiver
AD867_22545	COG3678	ATP-independent chaperone mediated protein folding
AD867_22560	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AD867_22585	COG3691	Protein conserved in bacteria
AD867_22590	COG0589	response to stress
AD867_22600	COG1494	fructose-1,6-bisphosphatase
AD867_22625	COG1575	Belongs to the MenA family. Type 1 subfamily
AD867_22630	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AD867_22640	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AD867_22645	COG1609	Transcriptional regulator
AD867_22650	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AD867_22660	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AD867_22670	COG0626	cystathionine gamma-synthase activity
AD867_22675	COG0460	homoserine dehydrogenase
AD867_22675	COG0527	aspartate kinase activity
AD867_22685	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AD867_22690	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AD867_22695	COG0697	spore germination
AD867_22715	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AD867_22720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AD867_22730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AD867_22735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AD867_22745	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AD867_22750	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AD867_22755	COG2207	Transcriptional regulator
AD867_22760	COG2194	sulfuric ester hydrolase activity
AD867_22790	COG3385	transposase activity
AD867_22795	COG4948	Mandelate Racemase Muconate Lactonizing
AD867_22800	COG2271	Major facilitator Superfamily
AD867_22805	COG3677	Transposase
AD867_22820	COG0583	DNA-binding transcription factor activity
AD867_22850	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AD867_22880	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AD867_22880	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AD867_22920	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AD867_22925	COG0250	Participates in transcription elongation, termination and antitermination
AD867_22960	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AD867_22970	COG2104	thiamine diphosphate biosynthetic process
AD867_22975	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AD867_23010	COG3068	Protein conserved in bacteria
AD867_23015	COG0776	regulation of translation
AD867_23025	COG3678	ATP-independent chaperone mediated protein folding
AD867_23030	COG4191	Histidine kinase
AD867_23035	COG2204	response regulator
AD867_23040	COG0151	Belongs to the GarS family
AD867_23070	COG0456	acetyltransferase
AD867_23085	COG2224	Isocitrate lyase
AD867_23105	COG1414	Transcriptional regulator
AD867_23110	COG0646	methionine synthase
AD867_23110	COG1410	methionine synthase
AD867_23115	COG1283	sodium-dependent phosphate transmembrane transporter activity
AD867_23180	COG2963	transposase activity
AD867_23200	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AD867_23205	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AD867_23205	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AD867_23210	COG3647	Membrane
AD867_23215	COG2211	Major facilitator Superfamily
AD867_23220	COG1486	melibiose metabolic process
AD867_23235	COG1982	Orn Lys Arg decarboxylase major
AD867_23240	COG2207	Transcriptional regulator
AD867_23245	COG0531	amino acid
AD867_23250	COG2194	sulfuric ester hydrolase activity
AD867_23255	COG0745	RESPONSE REGULATOR receiver
AD867_23260	COG0642	Histidine kinase
AD867_23270	COG0477	Major facilitator Superfamily
AD867_23280	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AD867_23285	COG2824	Alkylphosphonate utilization operon protein PhnA
AD867_23290	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AD867_23300	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AD867_23315	COG3677	Transposase
AD867_23330	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AD867_23335	COG2207	Transcriptional regulator
AD867_23340	COG0789	Transcriptional regulator
AD867_23345	COG2252	PERMEase
AD867_23350	COG0025	NhaP-type Na H and K H
AD867_23355	COG1357	PFAM Pentapeptide repeats (8 copies)
AD867_23365	COG3162	membrane
AD867_23385	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AD867_23390	COG0437	4 iron, 4 sulfur cluster binding
AD867_23395	COG3301	Polysulphide reductase, NrfD
AD867_23400	COG1138	Cytochrome C-type biogenesis protein
AD867_23405	COG3088	subunit of a heme lyase
AD867_23410	COG4235	cytochrome complex assembly
AD867_23415	COG1301	dicarboxylic acid transport
AD867_23420	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AD867_23425	COG3383	formate dehydrogenase (NAD+) activity
AD867_23430	COG3383	formate dehydrogenase (NAD+) activity
AD867_23460	COG3677	Transposase
AD867_23470	COG0629	single-stranded DNA binding
AD867_23475	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AD867_23480	COG2315	Protein conserved in bacteria
AD867_23485	COG0432	Pfam Uncharacterised protein family UPF0047
AD867_23490	COG3700	Belongs to the class B bacterial acid phosphatase family
AD867_23500	COG1448	Aminotransferase
AD867_23505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AD867_23510	COG0305	Participates in initiation and elongation during chromosome replication
AD867_23515	COG0604	alcohol dehydrogenase
AD867_23540	COG0735	belongs to the Fur family
AD867_23545	COG3237	CsbD-like
AD867_23550	COG0534	Mate efflux family protein
AD867_23560	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AD867_23605	COG2182	Extracellular solute-binding protein
AD867_23610	COG1175	transmembrane transport
AD867_23615	COG3833	ABC-type maltose transport systems, permease component
AD867_23620	COG2814	Major facilitator Superfamily
AD867_23620	COG0477	Major facilitator Superfamily
AD867_23640	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AD867_23665	COG0527	aspartate kinase activity
AD867_23670	COG4372	Transposase
AD867_23675	COG3436	PFAM IS66 Orf2 family protein
AD867_23685	COG2963	transposase activity
AD867_23700	COG3366	ferrous iron transmembrane transporter activity
AD867_23705	COG0700	Nucleoside recognition
AD867_23710	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AD867_23715	COG0583	DNA-binding transcription factor activity
AD867_23735	COG3677	Transposase
AD867_23750	COG2186	Transcriptional regulator
AD867_23760	COG0246	Mannitol dehydrogenase
AD867_23775	COG2610	gluconate transmembrane transporter activity
AD867_23780	COG3539	Fimbrial protein
AD867_23785	COG3539	Fimbrial protein
AD867_23790	COG3539	Fimbrial protein
AD867_23805	COG3677	Transposase
AD867_23810	COG3188	usher protein
AD867_23815	COG3121	Chaperone
AD867_23820	COG3539	Fimbrial protein
AD867_23830	COG4974	Belongs to the 'phage' integrase family
AD867_23835	COG0582	viral genome integration into host DNA
AD867_23850	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AD867_23870	COG3677	Transposase
AD867_23880	COG0440	acetolactate synthase activity
AD867_23885	COG0440	acetolactate synthase activity
AD867_23890	COG2963	transposase activity
AD867_23905	COG2801	Transposase and inactivated derivatives
AD867_23910	COG3677	Transposase
AD867_23930	COG0582	viral genome integration into host DNA
AD867_23940	COG1064	alcohol dehydrogenase
AD867_23945	COG0433	COG0433 Predicted ATPase
AD867_23950	COG0795	lipopolysaccharide-transporting ATPase activity
AD867_23955	COG0795	lipopolysaccharide-transporting ATPase activity
AD867_23965	COG2927	DNA polymerase III (CHI subunit)
AD867_23975	COG4269	membrane
AD867_23980	COG0456	acetyltransferase
AD867_23985	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AD867_23995	COG3677	Transposase
AD867_24010	COG2731	YhcH YjgK YiaL family protein
AD867_24015	COG1309	transcriptional regulator
AD867_24020	COG1028	Short-chain dehydrogenase reductase Sdr
AD867_24025	COG0251	oxidation-reduction process
AD867_24050	COG0251	oxidation-reduction process
AD867_24055	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AD867_24060	COG1609	Transcriptional regulator
AD867_24065	COG1263	PTS System
AD867_24065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AD867_24070	COG0366	Alpha amylase catalytic
AD867_24075	COG1328	CTP reductase activity
AD867_24080	COG0602	queuosine metabolic process
AD867_24090	COG0312	modulator of DNA gyrase
AD867_24100	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AD867_24110	COG3385	transposase activity
AD867_24115	COG1172	Belongs to the binding-protein-dependent transport system permease family
AD867_24120	COG1172	Belongs to the binding-protein-dependent transport system permease family
AD867_24125	COG1129	ABC transporter
AD867_24135	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AD867_24140	COG2105	PFAM AIG2 family protein
AD867_24145	COG2911	Protein conserved in bacteria
AD867_24150	COG0729	surface antigen
AD867_24165	COG1253	flavin adenine dinucleotide binding
AD867_24175	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AD867_24190	COG0737	Belongs to the 5'-nucleotidase family
AD867_24195	COG1733	regulation of RNA biosynthetic process
AD867_24200	COG0702	epimerase
AD867_24205	COG0697	spore germination
AD867_24215	COG1113	amino acid transport
AD867_24220	COG0545	Peptidyl-prolyl cis-trans isomerase
AD867_24225	COG3061	Opacity-associated protein A
AD867_24230	COG1309	transcriptional regulator
AD867_24250	COG3677	Transposase
AD867_24265	COG3677	Transposase
AD867_24280	COG1309	transcriptional regulator
AD867_24295	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AD867_24300	COG1027	Aspartate ammonia-lyase
AD867_24305	COG3030	protein affecting phage T7 exclusion by the F plasmid
AD867_24310	COG0531	amino acid
AD867_24335	COG3677	Transposase
AD867_24345	COG1509	lysine 2,3-aminomutase activity
AD867_24355	COG5510	response to toxic substance
AD867_24360	COG5510	response to toxic substance
AD867_24365	COG2076	Multidrug Resistance protein
AD867_24370	COG3040	lipid binding
AD867_24375	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AD867_24390	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AD867_24395	COG1053	succinate dehydrogenase
AD867_24405	COG0531	amino acid
AD867_24410	COG1662	PFAM IS1 transposase
AD867_24415	COG3677	Transposase
AD867_24425	COG3264	Mechanosensitive ion channel
AD867_24425	COG1511	domain protein
AD867_24470	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AD867_24475	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AD867_24475	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AD867_24480	COG0802	atpase or kinase
AD867_24485	COG0860	N-Acetylmuramoyl-L-alanine amidase
AD867_24505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AD867_24510	COG0330	HflC and HflK could
AD867_24515	COG0330	HflC and HflK could
AD867_24520	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AD867_24540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AD867_24545	COG3677	Transposase
AD867_24560	COG5463	Belongs to the UPF0441 family
AD867_24565	COG0754	glutathionylspermidine amidase activity
AD867_24570	COG1960	acyl-CoA dehydrogenase activity
AD867_24580	COG3677	Transposase
AD867_24585	COG1960	acyl-CoA dehydrogenase activity
AD867_24595	COG3650	response to hydrogen peroxide
AD867_24600	COG1073	alpha beta
AD867_24620	COG3414	Phosphotransferase system galactitol-specific IIB component
AD867_24680	COG2963	transposase activity
AD867_24710	COG0732	type I restriction modification DNA specificity domain
AD867_24725	COG3677	Transposase
AD867_24740	COG0523	cobalamin synthesis protein
AD867_24745	COG2879	small protein
AD867_24750	COG1966	Carbon starvation protein
AD867_24760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AD867_24770	COG1234	tRNA 3'-trailer cleavage
AD867_24790	COG3971	2-oxopent-4-enoate hydratase activity
AD867_24800	COG3384	dioxygenase
AD867_24805	COG1012	belongs to the aldehyde dehydrogenase family
AD867_24810	COG0179	Fumarylacetoacetate (FAA) hydrolase
AD867_24815	COG1846	Transcriptional regulator
AD867_24820	COG0840	transmembrane signaling receptor activity
AD867_24825	COG2271	Major facilitator Superfamily
AD867_24830	COG1802	Transcriptional regulator
AD867_24850	COG1484	DNA-dependent DNA replication
AD867_24865	COG2966	Psort location CytoplasmicMembrane, score
AD867_24870	COG3677	Transposase
AD867_24880	COG2197	response regulator
AD867_24885	COG2197	response regulator
AD867_24890	COG4114	ferric iron reductase
AD867_24920	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AD867_24925	COG0456	acetyltransferase
AD867_24930	COG1011	Hydrolase
AD867_24940	COG2823	Periplasmic or secreted lipoprotein
AD867_24950	COG4667	esterase of the alpha-beta hydrolase superfamily
AD867_24955	COG0084	hydrolase, TatD family'
AD867_24960	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AD867_24965	COG1328	CTP reductase activity
AD867_25000	COG0095	Lipoate-protein ligase
AD867_25000	COG3726	membrane protein affecting hemolysin expression
AD867_25015	COG0560	Phosphoserine phosphatase
AD867_25020	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AD867_25025	COG3172	ATPase kinase involved in NAD metabolism
AD867_25025	COG1056	cytidyltransferase-related domain
AD867_25035	COG0488	(ABC) transporter
AD867_25040	COG0741	lytic transglycosylase activity
AD867_25060	COG2207	Transcriptional regulator
AD867_25060	COG3708	Transcriptional regulator
AD867_25065	COG3045	CreA protein
AD867_25070	COG0745	RESPONSE REGULATOR receiver
AD867_25075	COG2205	protein histidine kinase activity
AD867_25080	COG4452	Inner membrane protein CreD
AD867_25085	COG0745	RESPONSE REGULATOR receiver
AD867_25095	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AD867_25225	COG3385	transposase activity
AD867_25235	COG3436	PFAM IS66 Orf2 family protein
AD867_25325	COG3344	reverse transcriptase
AD867_25355	COG2801	Transposase and inactivated derivatives
AD867_25370	COG2801	Transposase and inactivated derivatives
AD867_25375	COG2963	transposase activity
AD867_25405	COG3547	Transposase (IS116 IS110 IS902 family)
AD867_25460	COG1662	PFAM IS1 transposase
AD867_25480	COG4372	Transposase
AD867_25485	COG1484	DNA-dependent DNA replication
AD867_25515	COG2801	Transposase and inactivated derivatives
AD867_25580	COG2801	Transposase and inactivated derivatives
AD867_25635	COG3344	reverse transcriptase
AD867_25730	COG3436	PFAM IS66 Orf2 family protein
AD867_25755	COG2963	transposase activity
AD867_25770	COG3436	PFAM IS66 Orf2 family protein
AD867_25775	COG4372	Transposase
AD867_25825	COG2433	Pfam Transposase IS66
AD867_25830	COG5302	Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid
AD867_25865	COG3385	transposase activity
AD867_25890	COG2801	Transposase and inactivated derivatives
AD867_25910	COG0726	polysaccharide deacetylase
AD867_25915	COG0297	glycogen (starch) synthase activity
AD867_25920	COG2990	Protein conserved in bacteria
AD867_25980	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AD867_26085	COG2963	transposase activity
AD867_26135	COG3328	transposase activity
AD867_26145	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AD867_26150	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AD867_26155	COG0745	RESPONSE REGULATOR receiver
AD867_26165	COG3316	Transposase and inactivated derivatives
AD867_26185	COG0459	protein refolding
AD867_26195	COG3316	Transposase and inactivated derivatives
AD867_26200	COG3316	Transposase and inactivated derivatives
AD867_26205	COG3316	Transposase and inactivated derivatives
AD867_26245	COG3316	Transposase and inactivated derivatives
AD867_26265	COG3316	Transposase and inactivated derivatives
AD867_26540	COG2963	transposase activity