locus-tag class description BZ172_00005 ENOG4105VT2 5-hydroxyisourate hydrolase BZ172_00020 ENOG4108MEK Metal-binding protein YodA BZ172_00025 ENOG4108VKM cytochrome b561 BZ172_00050 ENOG4105TNG K13735 adhesin invasin BZ172_00135 ENOG4107R11 Transcriptional regulator BZ172_00145 ENOG4105UQX Mate efflux family protein BZ172_00165 ENOG4105FYV Amp nucleosidase BZ172_00170 ENOG4105CSH Transporter BZ172_00185 ENOG4106P55 Transcriptional regulator BZ172_00210 ENOG4108YZT Adenosylcobinamide kinase BZ172_00215 ENOG4108P62 biosynthesis protein (CbiG) BZ172_00225 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BZ172_00230 ENOG4105KNY Microcompartments protein BZ172_00235 ENOG4105EHR propanediol utilization protein pduB BZ172_00240 ENOG4105DMB glycerol dehydratase BZ172_00245 ENOG4105YCI dehydratase medium subunit BZ172_00250 ENOG4108ZFT Dehydratase small subunit BZ172_00255 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit BZ172_00265 ENOG4105KNY Microcompartments protein BZ172_00270 ENOG4105KNY Microcompartments protein BZ172_00275 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) BZ172_00285 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml BZ172_00300 ENOG4108EKI Dehydrogenase BZ172_00315 ENOG4105M3W utilization protein BZ172_00320 ENOG4105KTW ethanolamine utilization protein BZ172_00330 ENOG4105DR8 Membrane BZ172_00335 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) BZ172_00340 ENOG4105DZ1 carboxypeptidase BZ172_00345 ENOG4105CJB Exodeoxyribonuclease I BZ172_00355 ENOG4105CUC YeeE YedE family protein BZ172_00360 ENOG4105CUB amino acid BZ172_00365 ENOG4105EQ1 Transcriptional regulator BZ172_00370 ENOG4108535 NAD dependent epimerase/dehydratase family BZ172_00375 ENOG4105KRQ Addiction module toxin, Txe YoeB family BZ172_00380 ENOG4105VTW prevent-host-death family BZ172_00410 ENOG4105ECC imidazole-glycerol-phosphate dehydratase BZ172_00415 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BZ172_00430 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase BZ172_00440 ENOG4105C6Y Udp-glucose 6-dehydrogenase BZ172_00445 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BZ172_00450 ENOG4107QKV phosphomannomutase BZ172_00455 ENOG4105CJT Mannose-1-phosphate guanylyltransferase BZ172_00460 ENOG4106CD9 glycosyl transferase group 1 BZ172_00465 ENOG4105FGF GDP-mannose mannosyl hydrolase BZ172_00470 ENOG4105C30 Nad-dependent epimerase dehydratase BZ172_00475 ENOG4105C0K Gdp-mannose 4,6-dehydratase BZ172_00480 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF BZ172_00485 ENOG4105ECJ Glycosyl Transferase BZ172_00490 ENOG4108NYJ Colanic acid BZ172_00495 ENOG4107RXY Glycosyl transferase BZ172_00500 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB BZ172_00505 ENOG41090RK glycosyl transferase BZ172_00510 ENOG4105D75 Capsular exopolysaccharide family BZ172_00515 ENOG4105KJF protein tyrosine phosphatase BZ172_00520 ENOG4105DAY polysaccharide export protein BZ172_00525 ENOG4105EE5 Membrane protein terC BZ172_00530 ENOG4108GAE asmA family BZ172_00540 ENOG4105DBI uridine monophosphokinase BZ172_00545 ENOG4105BZU Histidine kinase BZ172_00550 ENOG4105D03 DNA-3-methyladenine glycosylase II BZ172_00555 ENOG4105R8A Heat shock protein BZ172_00560 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding BZ172_00565 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase BZ172_00570 ENOG4108M24 von Willebrand factor, type A BZ172_00600 ENOG4105EB3 Histidine kinase BZ172_00605 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ172_00625 ENOG4105KWI UPF0339 protein BZ172_00630 ENOG4105CFP Peptidase U32 BZ172_00640 ENOG41076Z6 Uncharacterized protein yegR BZ172_00655 ENOG4107WTH Galactitol-1-phosphate dehydrogenase BZ172_00660 ENOG4105DT3 PTS system, galactitol-specific IIc component BZ172_00665 ENOG41090UW PTS System BZ172_00670 ENOG41082GB PTS system galactitol-specific transporter subunit IIA BZ172_00685 ENOG41082GB PTS system galactitol-specific transporter subunit IIA BZ172_00705 ENOG4105EIE fructose-bisphosphate aldolase BZ172_00710 ENOG4105EAA nucleoside BZ172_00715 ENOG4108KD5 ADP-ribosylation crystallin J1 BZ172_00720 ENOG4108TFM Kinase, PfkB family BZ172_00725 ENOG4105FDP GntR family transcriptional regulator BZ172_00730 ENOG4108UQ1 hydrolase, family 25 BZ172_00735 ENOG4105DWF phosphomethylpyrimidine kinase BZ172_00755 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly BZ172_00760 ENOG410662B Type-1 fimbrial protein BZ172_00765 ENOG4105CW0 outer membrane usher protein BZ172_00780 ENOG4105CW0 outer membrane usher protein BZ172_00785 ENOG4108MQF Chaperone BZ172_00790 ENOG41063W2 Fimbrial protein BZ172_00795 ENOG41067AK Protein of unknown function (DUF2574) BZ172_00800 ENOG4105D1F ATP-binding protein BZ172_00835 ENOG4105DEG Vwa containing coxe family protein BZ172_00840 ENOG410903U zinc ion binding BZ172_00845 ENOG4108YCW (LipO)protein BZ172_00850 ENOG4108W15 Protein of unknown function (DUF1456) BZ172_00855 ENOG4108NEV two component transcriptional regulator, LytTR family BZ172_00860 ENOG4108HRK Histidine kinase BZ172_00865 ENOG4106FE3 DNA repair BZ172_00900 ENOG4108WF3 methyltransferase BZ172_00935 ENOG4108XDN Transcriptional regulator BZ172_00945 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component BZ172_00950 ENOG4108IJ8 ABC transporter BZ172_00955 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component BZ172_00960 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system BZ172_00965 ENOG4107QK4 glycoside hydrolase, family 3 domain protein BZ172_00970 ENOG4105CXG d-lactate dehydrogenase BZ172_00975 ENOG41061WM D-Alanyl-D-Alanine BZ172_00980 ENOG41069YE inner membrane protein yohC BZ172_00985 ENOG4105KHU inner membrane protein YohD BZ172_00990 ENOG4105H9W Short-chain dehydrogenase reductase Sdr BZ172_00995 ENOG4105ETP RND efflux system, outer membrane lipoprotein BZ172_01010 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) BZ172_01020 ENOG41067MG lrgb family BZ172_01030 ENOG4107GZ4 SanA protein BZ172_01035 ENOG4105Y9N Membrane BZ172_01045 ENOG4107SJI Dehydrogenase BZ172_01050 ENOG4108HWV )-transporter BZ172_01055 ENOG4105C2J ABC transporter BZ172_01060 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator BZ172_01065 ENOG41060NJ transcriptional regulator BZ172_01075 ENOG4105DHF Membrane BZ172_01095 ENOG4105D05 Receptor BZ172_01100 ENOG4108IQI permease BZ172_01110 ENOG4105DUM transcriptional regulator, lysR family BZ172_01115 ENOG4105HMI Membrane BZ172_01125 ENOG4105DD7 kinase (PfkB family BZ172_01130 ENOG4105D9N nucleoside BZ172_01140 ENOG4108Y4K DNA-binding transcriptional activator BZ172_01145 ENOG4105D9N nucleoside BZ172_01150 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) BZ172_01155 ENOG4105DD7 kinase (PfkB family BZ172_01160 ENOG4105DM4 PTS System BZ172_01165 ENOG4105DE4 1-phosphofructokinase BZ172_01170 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein BZ172_01175 ENOG4105S8Q sugar efflux transporter BZ172_01180 ENOG4105KRS Proteinase inhibitor BZ172_01190 ENOG4105DEI Mannitol dehydrogenase BZ172_01195 ENOG4105CKI cobalamin synthesis protein BZ172_01200 ENOG41076MN Phosphoesterase, PA-phosphatase related BZ172_01205 ENOG4107TT5 NLP P60 protein BZ172_01210 ENOG4105CXC rtn protein BZ172_01215 ENOG4105E43 Extracellular solute-binding protein, family 5 BZ172_01220 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component BZ172_01225 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component BZ172_01230 ENOG4108JQ5 ABC transporter BZ172_01235 ENOG4105HG6 BZ172_01250 ENOG4105I08 Pseudouridine synthase BZ172_01260 ENOG4105CFI type iii restriction protein res subunit BZ172_01280 ENOG4105E68 Sulfatase BZ172_01290 ENOG4108MGN ATP-binding component of a transport system BZ172_01295 ENOG4108MGN ATP-binding component of a transport system BZ172_01300 ENOG4108MVM Transposase BZ172_01320 ENOG4108ZQS transposase BZ172_01340 ENOG4105WH1 Two component transcriptional regulator luxr family BZ172_01345 ENOG4105KWW Biogenesis protein BZ172_01350 ENOG4107QX9 Thiol disulfide interChange protein BZ172_01355 ENOG4105DA4 cytochrome c-type biogenesis protein BZ172_01365 ENOG4105X3C heme exporter protein BZ172_01370 ENOG41060IM Heme exporter protein BZ172_01375 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) BZ172_01385 ENOG4105CUW cytochrome C-TYPE protein BZ172_01390 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) BZ172_01395 ENOG4105GXZ Ferredoxin-type protein NapH BZ172_01400 ENOG4108BGM Quinol dehydrogenase periplasmic component BZ172_01410 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase BZ172_01415 ENOG4108ZNS ferredoxin-type protein NapF BZ172_01435 ENOG4105IBP Cyclic peptide transporter BZ172_01440 ENOG4105CF1 Alkylated DNA repair protein BZ172_01445 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BZ172_01450 ENOG4105CJ2 (LipO)protein BZ172_01455 ENOG4105FCK Membrane BZ172_01485 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC BZ172_01490 ENOG41068CG regulatoR BZ172_01500 ENOG4105BZU Histidine kinase BZ172_01505 ENOG4105BZU Histidine kinase BZ172_01510 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BZ172_01515 ENOG4107QP7 CoA-transferase subunit A BZ172_01520 ENOG4107QNJ CoA-transferase subunit B BZ172_01525 ENOG4105CRW Short chain fatty acid transporter BZ172_01530 ENOG4105CHU acetyl-coa acetyltransferase BZ172_01535 ENOG4105EDV vault protein BZ172_01540 ENOG41081SK signal peptide protein BZ172_01545 ENOG4107S52 alpha-2-macroglobulin domain protein BZ172_01565 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) BZ172_01570 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ172_01580 ENOG4107GHC outer membrane autotransporter BZ172_01585 ENOG4108ZQS transposase BZ172_01595 ENOG4108MVM Transposase BZ172_01610 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BZ172_01620 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BZ172_01625 ENOG4105XPH Ferredoxin BZ172_01665 ENOG4107R11 Transcriptional regulator BZ172_01670 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase BZ172_01675 ENOG4105CXY transporter BZ172_01680 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A BZ172_01690 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BZ172_01695 ENOG4105DNE Transposase BZ172_01705 ENOG4105CSP Major Facilitator Superfamily BZ172_01715 ENOG4107258 Transcriptional regulator BZ172_01725 ENOG4108UII YfaZ family BZ172_01755 ENOG4105F73 Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) BZ172_01770 ENOG4105U65 Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity) BZ172_01775 ENOG4106GZG polymyxin resistance protein B BZ172_01785 ENOG4105CEY Amp-dependent synthetase and ligase BZ172_01795 ENOG4108IPT Naphthoate synthase BZ172_01810 ENOG4105E4F Isochorismate synthase BZ172_01815 ENOG4105TNS Conserved Protein BZ172_01855 ENOG4105GDX Domain of unknown function (DUF1877) BZ172_01865 ENOG4105C8S subunit m BZ172_01870 ENOG4105D65 subunit l BZ172_01880 ENOG4107UFS subunit j BZ172_01895 ENOG4108IEH NADH dehydrogenase subunit g BZ172_01900 ENOG4107QIZ NADH dehydrogenase BZ172_01905 ENOG4105GKE subunit e BZ172_01930 ENOG4107NQ8 LysR family Transcriptional regulator BZ172_01940 ENOG4105CHM Aminotransferase BZ172_01950 ENOG4107QWE )-transporter BZ172_01975 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BZ172_01980 ENOG4105C6K Malic enzyme BZ172_01985 ENOG4105CSX c4-dicarboxylate anaerobic carrier BZ172_01990 ENOG4105PTV Nudix Hydrolase BZ172_01995 ENOG4108RE9 Phosphodiesterase BZ172_02000 ENOG4108SHQ Glutathione S-transferase BZ172_02005 ENOG4105CYM Glutathione S-transferase BZ172_02010 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase BZ172_02015 ENOG4105ECP epimerase BZ172_02020 ENOG4105DNE Transposase BZ172_02045 ENOG4108JEH abc transporter atp-binding protein BZ172_02050 ENOG4106YG3 ABC transporter BZ172_02055 ENOG4105DSP amino acid AbC transporter BZ172_02060 ENOG4105E89 ABC transporter BZ172_02065 ENOG4105E89 ABC transporter BZ172_02070 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase BZ172_02075 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase BZ172_02080 ENOG4105E96 Colicin v production protein BZ172_02090 ENOG4108S3P Sporulation domain protein BZ172_02095 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BZ172_02105 ENOG4105DQR SNARE associated Golgi BZ172_02115 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BZ172_02125 ENOG4106WZ1 flagella biosynthesis regulator BZ172_02130 ENOG4105F9N Major Facilitator Superfamily BZ172_02140 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ172_02150 ENOG4105MH2 YfcL protein BZ172_02155 ENOG4108BPE -transporting atpase BZ172_02160 ENOG4105EJ9 Membrane BZ172_02190 ENOG4105US4 fimbrial-like protein yfcP BZ172_02195 ENOG4105UGQ Fimbrial BZ172_02200 ENOG4105NEV Fimbrial BZ172_02210 ENOG4106PG1 outer membrane usher protein BZ172_02220 ENOG4108BY2 phosphohistidine phosphatase BZ172_02225 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BZ172_02235 ENOG4105KZW UPF0381 protein BZ172_02245 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation BZ172_02250 ENOG410836F Transposase BZ172_02285 ENOG410903C (LipO)protein BZ172_02290 ENOG4105S64 Formate nitrite transporter BZ172_02300 ENOG4105DFP Integrase BZ172_02310 ENOG4108MVM Transposase BZ172_02335 ENOG4105UZW Tail fiber assembly protein BZ172_02340 ENOG410685N tail fiber protein BZ172_02415 ENOG4105IM0 capsid protein BZ172_02425 ENOG4105F7J membrane-bound serine protease BZ172_02435 ENOG4107DE1 head-to-tail joining protein BZ172_02440 ENOG4105UZW Tail fiber assembly protein BZ172_02445 ENOG4105FKG DNA packaging protein BZ172_02450 ENOG4106YSC BZ172_02460 ENOG41064WM Uncharacterized protein YcgX BZ172_02470 ENOG4108MVM Transposase BZ172_02480 ENOG4108ZQS transposase BZ172_02505 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 BZ172_02510 ENOG4105KUS lysozyme BZ172_02515 ENOG4105QFS Lysis protein S homolog from lambdoid prophage BZ172_02535 ENOG4105HRS Antitermination protein BZ172_02550 ENOG4105RWQ Protein of unknown function (DUF1364) BZ172_02555 ENOG410757E Protein NinE homolog from lambdoid prophage DLP12 BZ172_02560 ENOG4108V2F protein ybcN in lambdoid DLP12 prophage regi BZ172_02595 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) BZ172_02605 ENOG41065VV Transcription inhibitory protein for the torCAD operon. Also acts as an excisionase and plays an essential role in the defective prophage CPS53 excision BZ172_02635 ENOG4105D7K pfkb domain protein BZ172_02655 ENOG4105VNT transposase (IS4 family) protein BZ172_02660 ENOG4108HKT sucrose-6-phosphate hydrolase BZ172_02665 ENOG4106NDP Transcriptional regulator BZ172_02680 ENOG4105C0R drug resistance transporter emrb qaca subfamily BZ172_02685 ENOG4105CW7 secretion protein, HlyD family BZ172_02690 ENOG4108WQH regulatoR BZ172_02695 ENOG4105BZU Histidine kinase BZ172_02700 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F BZ172_02705 ENOG4108N2Y auxin Efflux BZ172_02710 ENOG4105CFN oxalyl-CoA decarboxylase BZ172_02720 ENOG4108V08 YfdX protein BZ172_02735 ENOG4105W9M Membrane BZ172_02740 ENOG4105D1S lipid A biosynthesis BZ172_02750 ENOG4105CHM Aminotransferase BZ172_02770 ENOG4108HRK Histidine kinase BZ172_02775 ENOG4105DY9 regulatoR BZ172_02780 ENOG4108CIP transcriptional regulator BZ172_02790 ENOG4105CN9 Peptidase m42 family protein BZ172_02800 ENOG410863U PTS System BZ172_02805 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) BZ172_02820 ENOG4109076 Conserved Protein BZ172_02830 ENOG4105D9N nucleoside BZ172_02850 ENOG4105HZG regulatoR BZ172_02855 ENOG4105GXM Putative transcription regulator (DUF1323) BZ172_02895 ENOG4108M0I Transcriptional regulator BZ172_02900 ENOG4105DHU Bile acid BZ172_02905 ENOG4105VRT cytoplasmic protein BZ172_02930 ENOG4105C6T cysteine synthase BZ172_02935 ENOG4105KZ7 phosphocarrier protein hpr BZ172_02940 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BZ172_02945 ENOG4105C5Y PTS System BZ172_02950 ENOG4105VNT transposase (IS4 family) protein BZ172_02960 ENOG4105M0Y BZ172_02965 ENOG4105C6T cysteine synthase BZ172_02970 ENOG4108IJ6 ABC transporter BZ172_02975 ENOG4105ECW sulfate abc transporter BZ172_02980 ENOG4108I5D sulfate abc transporter BZ172_02985 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein BZ172_02990 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr BZ172_03005 ENOG4105C5Y PTS System BZ172_03015 ENOG4107S1E Beta-lactamase BZ172_03020 ENOG4105EZR dyp-type peroxidase family protein BZ172_03025 ENOG4105E7K (LipO)protein BZ172_03030 ENOG4105QZU Inner membrane protein YfeZ BZ172_03035 ENOG4108R6G acetyltransferase BZ172_03040 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase BZ172_03050 ENOG4108K3Z AraC family transcriptional regulator BZ172_03055 ENOG4108X49 Ethanolamine utilization protein EutK BZ172_03060 ENOG4106D67 ethanolamine utilization protein BZ172_03075 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase BZ172_03080 ENOG4105ENY Ethanolamine utilization protein eutH BZ172_03085 ENOG4105C0A alcohol dehydrogenase BZ172_03090 ENOG4107RWI ethanolamine utilization protein eutJ BZ172_03095 ENOG4108EKI Dehydrogenase BZ172_03100 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml BZ172_03105 ENOG4105KNY Microcompartments protein BZ172_03110 ENOG4107WUY phosphate acetyltransferase BZ172_03115 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase BZ172_03120 ENOG4105NDK ethanolamine utilization protein BZ172_03125 ENOG4106S4J ethanolamine utilization protein EutP BZ172_03130 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place BZ172_03135 ENOG4105C6K Malic enzyme BZ172_03145 ENOG4105CV1 Transketolase (EC 2.2.1.1) BZ172_03150 ENOG4108PVD exported protein BZ172_03160 ENOG4105BZ8 glutamate synthase BZ172_03165 ENOG4105BZU Histidine kinase BZ172_03170 ENOG4105BZS acriflavin resistance protein BZ172_03180 ENOG4105KUZ arsenate reductase BZ172_03195 ENOG4106KED esterase YpfH BZ172_03205 ENOG4105CGZ zinc metallopeptidase BZ172_03220 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BZ172_03230 ENOG4105RH4 Glycine cleavage system transcriptional repressor BZ172_03235 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BZ172_03240 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) BZ172_03245 ENOG4108JPZ Monovalent cation H antiporter subunit D BZ172_03250 ENOG4107TDF Formate hydrogenlyase subunit 4 BZ172_03255 ENOG4105D65 subunit l BZ172_03260 ENOG4105D65 subunit l BZ172_03265 ENOG4107WQX hydrogenase 4 membrane subunit BZ172_03270 ENOG4108JPZ Monovalent cation H antiporter subunit D BZ172_03275 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BZ172_03285 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit BZ172_03290 ENOG4105I6X formate hydrogenlyase maturation BZ172_03295 ENOG4108JUA Transcriptional regulator BZ172_03300 ENOG4105TMB Formate nitrite transporter BZ172_03305 ENOG410836F Transposase BZ172_03310 ENOG4105TMB Formate nitrite transporter BZ172_03315 ENOG4105C02 permease BZ172_03320 ENOG4105ERG peptidase m48, ste24p BZ172_03325 ENOG4105K89 arsenate reductase BZ172_03335 ENOG4105C2W permease BZ172_03355 ENOG4108V3E phosphoribosylglycinamide formyltransferase BZ172_03360 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BZ172_03365 ENOG4105C9X ppx gppa phosphatase BZ172_03370 ENOG4105BZU Histidine kinase BZ172_03380 ENOG41062G3 Protein of unknown function (DUF2633) BZ172_03390 ENOG4108ZMA Outer membrane lipoprotein BZ172_03395 ENOG41066DY Membrane BZ172_03405 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BZ172_03415 ENOG4105VPD cellular component movement BZ172_03430 ENOG4105N21 Membrane BZ172_03460 ENOG4108JQB penicillin-binding protein 1C BZ172_03465 ENOG4105DN3 alpha-2-macroglobulin domain protein BZ172_03470 ENOG4105KHC sulfurtransferase BZ172_03475 ENOG4105YYA enhanced serine sensitivity protein SseB BZ172_03485 ENOG4105WVQ Fe-S assembly protein IscX BZ172_03490 ENOG4108ZIT Ferredoxin, 2FE-2S BZ172_03510 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins BZ172_03525 ENOG4105CVS RNA methyltransferase TrmH family, group 1 BZ172_03535 ENOG4107XM9 (LipO)protein BZ172_03540 ENOG4108MN2 Stationary phase inducible protein CsiE BZ172_03545 ENOG4105D8G Major Facilitator superfamily BZ172_03555 ENOG4105FUY alpha subunit BZ172_03595 ENOG4108SB3 DoxX Family BZ172_03600 ENOG4108ZKT aldose 1-epimerase BZ172_03605 ENOG4105CPQ Dehydrogenase BZ172_03610 ENOG4105CNN ABC, transporter BZ172_03615 ENOG4108F37 ATP-binding component of a transport system BZ172_03620 ENOG4105FCA ABC transporter periplasmic-binding protein YphF BZ172_03645 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BZ172_03650 ENOG4108YZA Nitrogen regulatory protein pii BZ172_03655 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BZ172_03660 ENOG4108SKK alpha helix protein BZ172_03665 ENOG4107WP9 Histidine kinase BZ172_03685 ENOG4108Z6B deaminase BZ172_03690 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB BZ172_03695 ENOG4106G6Q Transcriptional regulator BZ172_03705 ENOG4108C33 Resolvase BZ172_03735 ENOG4108YXQ IS66 Orf2 family protein BZ172_03820 ENOG4108ZQS transposase BZ172_03830 ENOG4108MVM Transposase BZ172_03850 ENOG41063SR receptor BZ172_03870 ENOG4105E5H Transposase BZ172_03875 ENOG4108YXQ IS66 Orf2 family protein BZ172_03920 ENOG4107CBI conjugal transfer fertility inhibition protein BZ172_04000 ENOG410607W Transposase BZ172_04010 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding BZ172_04050 ENOG4105C3F Signal peptidase i BZ172_04060 ENOG4105WMJ Positive regulator of sigma E, RseC MucC BZ172_04065 ENOG4105VQK sigma E regulatory protein, MucB RseB BZ172_04070 ENOG41069PW sigma-e factor negative regulatory protein BZ172_04075 ENOG4105EMN RNA polymerase sigma factor BZ172_04085 ENOG4108IYU L-aspartate oxidase BZ172_04100 ENOG4108IYU L-aspartate oxidase BZ172_04110 ENOG4105C1J atp-dependent rna helicase BZ172_04115 ENOG41090KR LysR family transcriptional Regulator BZ172_04135 ENOG4105EIB trna rrna methyltransferase BZ172_04140 ENOG4105K63 Thioredoxin BZ172_04145 ENOG4106IUH DTW domain containing protein BZ172_04150 ENOG4105CD5 CoA-binding domain protein BZ172_04155 ENOG4105JIM Phosphatidylserine synthase BZ172_04160 ENOG4105T42 (LipO)protein BZ172_04165 ENOG4105CSH Transporter BZ172_04200 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ172_04205 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BZ172_04210 ENOG4105C34 Pseudouridine synthase BZ172_04215 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane BZ172_04220 ENOG4105VNT transposase (IS4 family) protein BZ172_04245 ENOG4105TKZ Tail Sheath BZ172_04325 ENOG4108T86 baseplate J family protein BZ172_04330 ENOG4105Y0G tail protein BZ172_04350 ENOG4108X9F tail fiber protein BZ172_04370 ENOG4108Z1B Cyclase dehydrase BZ172_04375 ENOG4105VDB UPF0125 protein BZ172_04380 ENOG4105VNT transposase (IS4 family) protein BZ172_04390 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA BZ172_04395 ENOG4105CQC Prephenate dehydratase BZ172_04400 ENOG4105EHE chorismate mutase- prephenate dehydrogenase BZ172_04405 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BZ172_04410 ENOG4105QP9 Protein of unknown function (DUF2799) BZ172_04430 ENOG4108WS1 BZ172_04450 ENOG4108KHX Diguanylate cyclase BZ172_04465 ENOG4108KHX Diguanylate cyclase BZ172_04470 ENOG41090EK ompa motb domain protein BZ172_04495 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY BZ172_04500 ENOG4106KVJ cytochrome C assembly protein BZ172_04505 ENOG4108JU6 CBS domain protein BZ172_04525 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BZ172_04530 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BZ172_04535 ENOG4105VNT transposase (IS4 family) protein BZ172_04545 ENOG4108ZQS transposase BZ172_04560 ENOG4105VNT transposase (IS4 family) protein BZ172_04565 ENOG4105EFC phage portal protein HK97 family BZ172_04575 ENOG4105CAR Terminase, large subunit BZ172_04590 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 BZ172_04595 ENOG4105KUS lysozyme BZ172_04600 ENOG4105QFS Lysis protein S homolog from lambdoid prophage BZ172_04640 ENOG4105HRS Antitermination protein BZ172_04645 ENOG4105KSK (crossover) junction endodeoxyribonuclease BZ172_04655 ENOG4105CDU Replicative dna helicase BZ172_04665 ENOG4108MVM Transposase BZ172_04670 ENOG4108ZQS transposase BZ172_04680 ENOG4108MGN ATP-binding component of a transport system BZ172_04750 ENOG4105E54 alpha-amylase BZ172_04755 ENOG4105EK3 May be involved in the control of utilization of gamma- aminobutyric acid (By similarity) BZ172_04760 ENOG4105D5U fad dependent oxidoreductase BZ172_04765 ENOG4105C26 Dehydrogenase BZ172_04770 ENOG4108JPW Aminotransferase BZ172_04775 ENOG4105C85 amino acid BZ172_04780 ENOG4108PVQ transcriptional regulator BZ172_04785 ENOG4109066 lysm domain bon superfamily protein BZ172_04790 ENOG4105VPI YqaE family transport protein BZ172_04795 ENOG41080HT Transcriptional regulator, arsr family BZ172_04800 ENOG4108V62 Rhodanese domain protein BZ172_04805 ENOG4108X73 DNA- binding protein BZ172_04810 ENOG410836F Transposase BZ172_04815 ENOG4108RNS Exports L-alanine (By similarity) BZ172_04820 ENOG4108WMJ Protein of unknown function (DUF2002) BZ172_04825 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) BZ172_04830 ENOG4105WAZ (Glutaredoxin-like protein) NrdH BZ172_04840 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BZ172_04845 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BZ172_04855 ENOG4108IJ7 Glycine betaine BZ172_04860 ENOG4108HQS Glycine betaine BZ172_04865 ENOG4105GIJ Glycine betaine BZ172_04875 ENOG4108UMN azlc family BZ172_04880 ENOG4105ZED uncharacterized protein ygaH BZ172_04885 ENOG4105NTK Transcriptional repressor Mpra BZ172_04890 ENOG4105CW7 secretion protein, HlyD family BZ172_04895 ENOG4105C0R drug resistance transporter emrb qaca subfamily BZ172_04910 ENOG4105W39 Membrane BZ172_04915 ENOG4107VXZ Hydrolase BZ172_04945 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) BZ172_04970 ENOG4107TH8 cina domain protein BZ172_04975 ENOG4105CVE Lytic murein transglycosylase BZ172_04980 ENOG410787A Pts system, glucitol sorbitol-specific BZ172_04985 ENOG4105DZY Pts system, glucitol sorbitol-specific BZ172_04990 ENOG4105VI0 Pts system, glucitol sorbitol-specific BZ172_05000 ENOG4105J92 DNA-binding transcriptional activator GutM BZ172_05005 ENOG410804X Transcriptional regulator BZ172_05035 ENOG4105C8H hydrogenase maturation protein Hypf BZ172_05040 ENOG4108RC0 Electron transport protein BZ172_05045 ENOG4105DDV Transcriptional regulator (LacI family BZ172_05050 ENOG4105C5Y PTS System BZ172_05055 ENOG4105CS2 ec 3.2.1.21 BZ172_05060 ENOG4108Z3N Transcriptional regulator BZ172_05065 ENOG4105RVE Uncharacterized protein conserved in bacteria (DUF2136) BZ172_05075 ENOG4108MG9 hydrogenase 3 maturation protease BZ172_05080 ENOG4105I6X formate hydrogenlyase maturation BZ172_05085 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit BZ172_05090 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit BZ172_05095 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BZ172_05100 ENOG4107TDF Formate hydrogenlyase subunit 4 BZ172_05105 ENOG4107R30 NADH dehydrogenase BZ172_05110 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) BZ172_05120 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA BZ172_05125 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) BZ172_05130 ENOG4107RSS Hydrogenase accessory protein HypB BZ172_05135 ENOG41083WG hydrogenase assembly chaperone BZ172_05140 ENOG4105CQS hydrogenase expression formation protein HypD BZ172_05145 ENOG4105C45 hydrogenase expression formation protein (HypE) BZ172_05160 ENOG4105VXR cytoplasmic protein BZ172_05190 ENOG4105MVE transcriptional regulator BZ172_05195 ENOG4105ZXK Dehydrogenase BZ172_05200 ENOG4105G63 Type III effector Hrp-dependent BZ172_05205 ENOG4105FB2 class II Aldolase BZ172_05210 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) BZ172_05215 ENOG4105C6Z Gluconate BZ172_05225 ENOG4108K5P (LipO)protein BZ172_05265 ENOG4105N0Z inner membrane protein ygbE BZ172_05285 ENOG4108MXK alkaline phosphatase isozyme conversion BZ172_05290 ENOG4105PWE CRISPR-associated protein cas2 BZ172_05305 ENOG410836F Transposase BZ172_05315 ENOG4108VWQ crispr-associated protein BZ172_05320 ENOG41060M0 Crispr-associated protein, cse4 family BZ172_05350 ENOG4105DTT CRISPR-associated helicase, cas3 BZ172_05355 ENOG4107635 Hok Gef family protein BZ172_05375 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BZ172_05380 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase BZ172_05385 ENOG4105WQV ferredoxin-like protein BZ172_05390 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BZ172_05395 ENOG4105YBM electron transfer flavoprotein subunit ygcQ BZ172_05400 ENOG4106IKH Electron transfer flavoprotein BZ172_05405 ENOG4105C54 Major Facilitator superfamily BZ172_05410 ENOG4107R3A FAD linked oxidase domain protein BZ172_05415 ENOG4105CHR reductase BZ172_05420 ENOG4105CHR reductase BZ172_05425 ENOG4108ITV Inner membrane protein yqcE BZ172_05450 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BZ172_05465 ENOG4105HA9 of methanol dehydrogenase type BZ172_05490 ENOG4105VNT transposase (IS4 family) protein BZ172_05505 ENOG4105DXN mazG family BZ172_05510 ENOG4105MZG transcriptional modulator of maze toxin, mazf BZ172_05515 ENOG4106A2Z transcriptional regulator antitoxin, MazE BZ172_05520 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BZ172_05530 ENOG4105BZU Histidine kinase BZ172_05535 ENOG4105EQX glucarate dehydratase BZ172_05540 ENOG4105EQX glucarate dehydratase BZ172_05545 ENOG4105DJB Major Facilitator Superfamily BZ172_05550 ENOG4105QDK Flavodoxin BZ172_05555 ENOG4105DR9 pseudouridine synthase BZ172_05560 ENOG4105WP7 tRNA pseudouridine synthase C BZ172_05580 ENOG4105EWT decarboxylase family BZ172_05585 ENOG4105C44 Serine transporter BZ172_05590 ENOG4105EJQ L-serine dehydratase BZ172_05600 ENOG4105C0A alcohol dehydrogenase BZ172_05605 ENOG4107W7X Aldolase BZ172_05610 ENOG4105EDR glucose galactose transporter BZ172_05620 ENOG4105CMG Carbohydrate kinase BZ172_05630 ENOG4107EDW L-fucose operon activator BZ172_05640 ENOG4105M08 Membrane BZ172_05645 ENOG4105ETT transcriptional Regulator, LysR family BZ172_05650 ENOG4105M5B (LipO)protein BZ172_05655 ENOG4105C9B Cysteine desulfurase BZ172_05660 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) BZ172_05665 ENOG4105CUZ uba thif-type nad fad binding protein BZ172_05670 ENOG4105CA3 membrane-bound lytic murein transglycosylase BZ172_05695 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BZ172_05700 ENOG4107QZM n-acetylglutamate synthase BZ172_05705 ENOG4107QYX exodeoxyribonuclease v alpha BZ172_05710 ENOG4107QKA exodeoxyribonuclease V beta BZ172_05715 ENOG4107QXK peptidase BZ172_05720 ENOG4105DSY exodeoxyribonuclease V, gamma BZ172_05725 ENOG4105RVB Prepilin peptidase dependent protein c BZ172_05730 ENOG4105SEN Protein of unknown function (DUF2509) BZ172_05735 ENOG4105JCS prepilin peptidase dependent protein BZ172_05740 ENOG4105IPU prepilin peptidase dependent protein A BZ172_05755 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase BZ172_05780 ENOG4105EE5 Membrane protein terC BZ172_05785 ENOG4105SUV lipoprotein YgdR BZ172_05800 ENOG4105VNT transposase (IS4 family) protein BZ172_05805 ENOG4105CPC Aldo Keto reductase BZ172_05825 ENOG41060NJ transcriptional regulator BZ172_05830 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BZ172_05835 ENOG4105RQF LysR family Transcriptional regulator BZ172_05850 ENOG4107QNK )-transporter BZ172_05855 ENOG4105CHR reductase BZ172_05865 ENOG4105CHU acetyl-coa acetyltransferase BZ172_05870 ENOG4108MHD transport protein BZ172_05875 ENOG4105ISV protein with bipartite regulator domain BZ172_05905 ENOG4108TC1 Transcriptional regulator BZ172_05910 ENOG4105FV3 BZ172_05940 ENOG4108YAB Invasion protein BZ172_05950 ENOG4108ZQS transposase BZ172_05955 ENOG4108MVM Transposase BZ172_05960 ENOG4108T88 BZ172_05970 ENOG4108K5P (LipO)protein BZ172_05980 ENOG4105C7W Xanthine dehydrogenase BZ172_05985 ENOG4108HR6 Dehydrogenase BZ172_05990 ENOG4108UTP (2Fe-2S)-binding domain protein BZ172_05995 ENOG4108JUB Transcriptional regulator BZ172_06000 ENOG4105IW6 Carbamoyltransferase BZ172_06005 ENOG4107RCH Diaminopropionate ammonia-lyase BZ172_06010 ENOG4107S4Y M20 DapE family protein YgeY BZ172_06020 ENOG4105C5B carbamate kinase BZ172_06025 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family BZ172_06030 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC BZ172_06035 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase BZ172_06040 ENOG4105BZ8 glutamate synthase BZ172_06045 ENOG4105VNT transposase (IS4 family) protein BZ172_06065 ENOG4107UUR Chlorohydrolase aminohydrolase BZ172_06070 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase BZ172_06075 ENOG4105C7W Xanthine dehydrogenase BZ172_06080 ENOG4107QUY Guanine deaminase BZ172_06085 ENOG4105C7N Xanthine uracil vitamin C permease BZ172_06090 ENOG4108R8B oxidoreductase Fe-S subunit BZ172_06095 ENOG4105BZ8 glutamate synthase BZ172_06115 ENOG4105C2W permease BZ172_06130 ENOG4105CRK lysyL-tRNA synthetase BZ172_06140 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BZ172_06145 ENOG4105T95 Thiol disulfide interChange protein BZ172_06150 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BZ172_06155 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) BZ172_06160 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB BZ172_06165 ENOG4105Y75 tpr repeat protein BZ172_06175 ENOG4108UT2 hemolysin iii BZ172_06185 ENOG4105CS2 ec 3.2.1.21 BZ172_06190 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BZ172_06210 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BZ172_06215 ENOG4105D0A hydroxylase BZ172_06220 ENOG4107RAQ aminopeptidase BZ172_06245 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BZ172_06265 ENOG4108JQ1 Dehydrogenase BZ172_06290 ENOG4105D5P Methylmalonyl-coA mutase BZ172_06295 ENOG4105DJT lAO AO transport system ATPase BZ172_06300 ENOG4108M7F enoyl-CoA hydratase isomerase BZ172_06305 ENOG4105CYC Transferase BZ172_06310 ENOG4105DEQ transcriptional regulator BZ172_06330 ENOG4105MPN Membrane BZ172_06335 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BZ172_06340 ENOG4105D64 Mechanosensitive ion channel BZ172_06350 ENOG4105D2N Aldolase BZ172_06385 ENOG4108JJB ABC transporter BZ172_06390 ENOG4108JJB ABC transporter BZ172_06395 ENOG4107Z1W Fructose transport system kinase BZ172_06415 ENOG4105CTS PTS system mannitol-specific BZ172_06420 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia BZ172_06425 ENOG4105CV1 Transketolase (EC 2.2.1.1) BZ172_06430 ENOG4108K0D peptidase, M48 BZ172_06440 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) BZ172_06470 ENOG4107QNK )-transporter BZ172_06480 ENOG4105RWS endonuclease I BZ172_06485 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BZ172_06490 ENOG4105D7Z glutathione synthase BZ172_06505 ENOG4105CZX twitching motility protein BZ172_06510 ENOG4105DFA alanine racemase domain protein BZ172_06515 ENOG4108VIA integral membrane protein BZ172_06525 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BZ172_06530 ENOG4105CSA Coproporphyrinogen iii oxidase BZ172_06540 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit BZ172_06545 ENOG41069H7 transport system small permease component BZ172_06595 ENOG4105DU1 integral membrane protein, terc BZ172_06605 ENOG4108UB4 uncharacterized protein ygjQ BZ172_06610 ENOG4108VKG metal-dependent hydrolase BZ172_06625 ENOG4105R48 this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase BZ172_06630 ENOG4108Z3N Transcriptional regulator BZ172_06635 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BZ172_06640 ENOG4107WCA isomerase BZ172_06650 ENOG4105E5D amino acid BZ172_06690 ENOG4108GH0 ATP-binding protein yghT BZ172_06695 ENOG4105CJ3 phosphate transporter BZ172_06700 ENOG4106032 Glutathionylspermidine synthase BZ172_06705 ENOG4105CYM Glutathione S-transferase BZ172_06710 ENOG41082MF Hydrogenase assembly chaperone hypC hupF BZ172_06715 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) BZ172_06720 ENOG4108WGS hydrogenase 2-specific chaperone BZ172_06725 ENOG4108USZ hydrogenase BZ172_06730 ENOG4105DPX Hydrogenase, large subunit BZ172_06735 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit BZ172_06740 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein BZ172_06745 ENOG4105E3S small subunit BZ172_06755 ENOG410900S Protein of unknown function (DUF2623) BZ172_06765 ENOG4105CPC Aldo Keto reductase BZ172_06775 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BZ172_06780 ENOG4108ZZF transport protein (ExbD) BZ172_06785 ENOG4105CWK Biopolymer transport protein, ExbB BZ172_06795 ENOG4105C28 cystathionine BZ172_06800 ENOG4108K81 inner membrane protein YghB BZ172_06805 ENOG4105CF7 AraC family transcriptional regulator BZ172_06815 ENOG4108I6A alcohol dehydrogenase BZ172_06820 ENOG4105CV8 reductase BZ172_06825 ENOG4105ZKC Conserved Protein BZ172_06835 ENOG4105CCT upf0313 protein BZ172_06840 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) BZ172_06845 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase BZ172_06855 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ172_06865 ENOG4105F4I Transcriptional regulator BZ172_06870 ENOG4105H4F exported protein BZ172_06875 ENOG4105XJC Two component transcriptional regulator (Winged helix family BZ172_06880 ENOG4105DHQ Histidine kinase BZ172_06885 ENOG4105NF4 modulator of drug activity BZ172_06890 ENOG4105VRH Antibiotic biosynthesis monooxygenase BZ172_06895 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ172_06900 ENOG4105IPS esterase BZ172_06905 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) BZ172_06910 ENOG4108SX3 cytoplasmic protein BZ172_06915 ENOG41087AY ADP-Ribose pyrophosphatase BZ172_06920 ENOG4105DFG type I secretion outer membrane protein BZ172_06935 ENOG4106032 Glutathionylspermidine synthase BZ172_06940 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BZ172_06960 ENOG4105W0Z cytoplasmic protein BZ172_06965 ENOG4105H8W Fimbrial protein BZ172_06975 ENOG4108MVM Transposase BZ172_06985 ENOG4108ZQS transposase BZ172_06995 ENOG4108TTM chaperone BZ172_07000 ENOG4108MY7 Fimbrial BZ172_07015 ENOG4105PV3 Inner membrane protein yqiJ BZ172_07020 ENOG4107S78 Band 7 protein BZ172_07040 ENOG4105I7R Adenylate cyclase BZ172_07050 ENOG4106MWK domain protein BZ172_07065 ENOG4107ZVW dihydroneopterin aldolase BZ172_07085 ENOG4106DSS Tartrate dehydratase subunit alpha BZ172_07105 ENOG4105VCC 30S ribosomal protein S21 BZ172_07110 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BZ172_07120 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ172_07125 ENOG4105VNT transposase (IS4 family) protein BZ172_07140 ENOG4105Q26 Siderophore-interacting protein BZ172_07150 ENOG4105NTW Transcriptional regulator BZ172_07155 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor BZ172_07170 ENOG4108Y51 tRNA-binding protein BZ172_07180 ENOG4105CQ4 Transcriptional regulator BZ172_07185 ENOG4105VNT transposase (IS4 family) protein BZ172_07190 ENOG4105CNT hydrolase family 2 BZ172_07195 ENOG4105CNT hydrolase family 2 BZ172_07200 ENOG4105FK9 beta-D-galactosidase beta subunit BZ172_07205 ENOG4105E5D amino acid BZ172_07215 ENOG4108GH0 ATP-binding protein yghT BZ172_07220 ENOG4108NDC ATP-binding protein yghS BZ172_07225 ENOG4106FPV ATP-binding protein YghR BZ172_07230 ENOG4108S55 polysaccharide biosynthesis protein BZ172_07260 ENOG4105I1J Autotransporter BZ172_07305 ENOG4105EQR Transposase IS116 IS110 IS902 BZ172_07320 ENOG4108UQV Membrane BZ172_07330 ENOG4105CXN decarboxylase BZ172_07345 ENOG4105EAA nucleoside BZ172_07360 ENOG4105CEN a g-specific adenine glycosylase BZ172_07375 ENOG41090ED Protein with unknown function (DUF469) BZ172_07380 ENOG4105K33 Periplasmic Protein BZ172_07385 ENOG4105HDK L-asparaginase BZ172_07390 ENOG4106MH3 alpha helix chain BZ172_07410 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) BZ172_07415 ENOG4105P66 Membrane BZ172_07420 ENOG4105CTX dehydratase BZ172_07430 ENOG4105DPW Major facilitator superfamily MFS_1 BZ172_07435 ENOG4105DPW Major facilitator superfamily MFS_1 BZ172_07495 ENOG4107YCY Transcriptional regulator BZ172_07500 ENOG4106W5V Membrane BZ172_07505 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) BZ172_07510 ENOG4105WAY exported protein BZ172_07515 ENOG4105NE1 Conserved Protein BZ172_07520 ENOG41090KG Inner membrane protein YqjE BZ172_07525 ENOG4105YJD BZ172_07530 ENOG4108VBZ doxx family BZ172_07540 ENOG4105KAF membrAne BZ172_07545 ENOG4105KAF membrAne BZ172_07555 ENOG4108CNN domain protein BZ172_07560 ENOG4106D80 Uncharacterized protein YhaL BZ172_07570 ENOG4105C44 Serine transporter BZ172_07575 ENOG4105EJQ L-serine dehydratase BZ172_07580 ENOG4105KME endoribonuclease L-psp BZ172_07585 ENOG4105C6N Formate acetyltransferase BZ172_07590 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BZ172_07600 ENOG4105C7B Threonine dehydratase BZ172_07605 ENOG410811B TRANSCRIPTIONal BZ172_07635 ENOG4105BZW Glycerate kinase BZ172_07640 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BZ172_07650 ENOG4105DJB Major Facilitator Superfamily BZ172_07655 ENOG4105CTX dehydratase BZ172_07675 ENOG4105ZEG Suppressor protein BZ172_07700 ENOG4105CW0 outer membrane usher protein BZ172_07715 ENOG4108ZQS transposase BZ172_07720 ENOG4108MVM Transposase BZ172_07730 ENOG4105I74 Fimbrial protein BZ172_07735 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BZ172_07750 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) BZ172_07755 ENOG4105W4M Transport-associated protein BZ172_07760 ENOG4107S21 permease BZ172_07765 ENOG4105K4T epimerase BZ172_07770 ENOG4107R7Y intracellular protease Pfpi family BZ172_07785 ENOG4108YYD acetyltransferase BZ172_07790 ENOG4105XPQ lipid carrier protein BZ172_07795 ENOG4105CFP Peptidase U32 BZ172_07800 ENOG4106RZ4 Peptidase U32 BZ172_07805 ENOG4105DEN Luciferase family BZ172_07810 ENOG4105CIC tryptophan-specific transport protein BZ172_07820 ENOG4105C1J atp-dependent rna helicase BZ172_07830 ENOG4105RT1 May be involved in cell division (By similarity) BZ172_07845 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BZ172_07860 ENOG4105CHV Transcription elongation factor NusA BZ172_07890 ENOG4105DIJ Phosphoethanolamine transferase BZ172_07910 ENOG4105EEI dihydropteroate synthase BZ172_07915 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BZ172_07920 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) BZ172_07925 ENOG4105HBR Rna-binding protein BZ172_07930 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BZ172_07935 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase BZ172_07945 ENOG4105QYV Membrane BZ172_07960 ENOG4105EAH synthase BZ172_07965 ENOG4105HVQ Regulatory factor of maltose metabolism BZ172_07975 ENOG4105VFK BolA family BZ172_07980 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane BZ172_07985 ENOG4105E3I toluene tolerance BZ172_07990 ENOG4107PE3 Mammalian cell entry related domain protein BZ172_07995 ENOG4105CY3 ABC transporter, permease BZ172_08000 ENOG4105DHJ ABC, transporter BZ172_08005 ENOG4105FEU K -dependent Na -Ca exchanger BZ172_08010 ENOG4105C2X Arabinose 5-phosphate isomerase BZ172_08015 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase BZ172_08020 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) BZ172_08025 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA BZ172_08030 ENOG4108IUZ ABC transporter BZ172_08035 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ172_08040 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA BZ172_08045 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN BZ172_08055 ENOG41080Z8 PHOSPHOCARRIER protein BZ172_08060 ENOG4108NIH transferase activity, transferring phosphorus-containing groups BZ172_08070 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain BZ172_08075 ENOG4105BZU Histidine kinase BZ172_08080 ENOG4105N5T Radical SAM Protein BZ172_08095 ENOG4105CBC glutamate synthase BZ172_08100 ENOG4105BZ8 glutamate synthase BZ172_08105 ENOG4105DFS Conserved Protein BZ172_08115 ENOG4108R66 Conserved Protein BZ172_08150 ENOG4105CEE C4-dicarboxylate transporter BZ172_08155 ENOG4105KB2 stringent starvation protein b BZ172_08160 ENOG4107MKT Stringent starvation protein a BZ172_08180 ENOG4105D6Z AFG1 family ATPase BZ172_08185 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III BZ172_08190 ENOG4105C0H protease BZ172_08195 ENOG4105C0H protease BZ172_08200 ENOG4105VNT transposase (IS4 family) protein BZ172_08215 ENOG4105RID UPF0379 protein yhcN BZ172_08220 ENOG4105UNR (Barnase) inhibitor BZ172_08245 ENOG4105D1U peptidase U62 modulator of DNA gyrase BZ172_08250 ENOG4105QD6 exported protein BZ172_08255 ENOG4105C03 ribonuclease BZ172_08265 ENOG4105VQ7 Rod shape-determining protein MreD BZ172_08270 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BZ172_08275 ENOG4105DFF Rod shape-determining protein mreb BZ172_08290 ENOG41062P1 Diguanylate cyclase phosphodiesterase BZ172_08295 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family BZ172_08310 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein BZ172_08315 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BZ172_08320 ENOG4105RG0 Membrane BZ172_08325 ENOG4108IA2 Sodium pantothenate symporter BZ172_08335 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BZ172_08340 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) BZ172_08345 ENOG4105CEC DNA methylase N-4 N-6 BZ172_08350 ENOG41061ME transport protein BZ172_08355 ENOG4108XG4 DNA-binding transcriptional regulator BZ172_08365 ENOG4105C1P efflux transporter, rnd family, mfp subunit BZ172_08370 ENOG4105BZS acriflavin resistance protein BZ172_08375 ENOG4105BZS acriflavin resistance protein BZ172_08410 ENOG4105EZ7 amino acid ABC transporter BZ172_08415 ENOG4105EZ7 amino acid ABC transporter BZ172_08420 ENOG4105DRP amino acid AbC transporter BZ172_08425 ENOG4105CDA abc transporter atp-binding protein BZ172_08465 ENOG4108Z0R Transferase BZ172_08470 ENOG4105SG3 Protein of unknown function (DUF1488) BZ172_08485 ENOG4108WI1 Dna topoisomerase BZ172_08495 ENOG4105C79 DNA protecting protein DprA BZ172_08515 ENOG4105C1A potassium transporter peripheral membrane BZ172_08525 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system BZ172_08530 ENOG4105W1Y Transcriptional regulator BZ172_08535 ENOG4105VTS DnaJ-like, subfamily C BZ172_08545 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BZ172_08550 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) BZ172_08560 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits BZ172_08565 ENOG41067V7 50S ribosomal protein L36 BZ172_08570 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BZ172_08575 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) BZ172_08585 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) BZ172_08600 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) BZ172_08615 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) BZ172_08625 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal BZ172_08635 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) BZ172_08640 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) BZ172_08645 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) BZ172_08650 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) BZ172_08660 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) BZ172_08665 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) BZ172_08680 ENOG4107ACA Calcium-binding protein required for initiation of chromosome replication BZ172_08685 ENOG410899B May play a regulatory role under conditions of derepressed gsp gene expression BZ172_08700 ENOG410899B May play a regulatory role under conditions of derepressed gsp gene expression BZ172_08765 ENOG4105WWK YheO domain protein BZ172_08770 ENOG4108V1T peptidylprolyl cis-trans isomerase BZ172_08780 ENOG4108YZY peptidylprolyl cis-trans isomerase BZ172_08785 ENOG4105VKU nucleicacid-binding protein BZ172_08805 ENOG4105C5H ABC transporter BZ172_08810 ENOG4105DNZ Alpha Beta Hydrolase BZ172_08820 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) BZ172_08825 ENOG4108UKZ OsmC family BZ172_08835 ENOG4107RYR Transcriptional regulator, Crp Fnr family BZ172_08840 ENOG410613R integral membrane protein, YccS YhfK family BZ172_08845 ENOG4105C8Y Acetylornithine aminotransferase BZ172_08850 ENOG4105DDQ anthranilate synthase BZ172_08855 ENOG4105MZU cell filamentation protein BZ172_08860 ENOG4106195 uncharacterized protein yhfG BZ172_08865 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BZ172_08880 ENOG4107QZF nitrite reductase NADPH large subunit BZ172_08885 ENOG4105WZK nitrite reductase NADPH small subunit BZ172_08890 ENOG4107V9H nitrite transporter BZ172_08900 ENOG4105VYH BZ172_08925 ENOG4107QHQ amino acid BZ172_08930 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine BZ172_08945 ENOG4108KPW sugar kinase BZ172_08950 ENOG4105FDP GntR family transcriptional regulator BZ172_08955 ENOG4106PKC pyridoxal phosphate binding BZ172_08960 ENOG4106M0N transport system permease protein BZ172_08965 ENOG4105MUZ Protein of unknown function DUF2620 BZ172_08970 ENOG41080QX K07048 phosphotriesterase-related protein BZ172_08985 ENOG4105RMW regulation of transcription, DNA-dependent BZ172_08990 ENOG4108M21 BZ172_08995 ENOG4105C31 Tryptophanyl-tRNA synthetase BZ172_09005 ENOG4105DJV ribulose-phosphate 3-epimerase BZ172_09010 ENOG4105DFE Dna adenine methylase BZ172_09015 ENOG4105EGB membrane protein DamX BZ172_09030 ENOG4105E4G Type IV pilus BZ172_09035 ENOG4105ITY Required for the use of extracellular DNA as a nutrient BZ172_09040 ENOG4105XPX DNA utilization protein HofO BZ172_09045 ENOG41065NF Fimbrial assembly family protein BZ172_09050 ENOG4108U1Q Pilus assembly protein BZ172_09055 ENOG4108JQC penicillin-binding protein 1A BZ172_09060 ENOG4107RK2 ADP-ribose diphosphatase NudE BZ172_09065 ENOG4105DQY intracellular growth attenuator BZ172_09070 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 BZ172_09075 ENOG4105VEJ Heat shock protein BZ172_09085 ENOG4108MAJ Membrane BZ172_09100 ENOG4105E0F Histidine kinase BZ172_09105 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BZ172_09115 ENOG4108RRZ Transcription elongation factor GreB BZ172_09120 ENOG4105BZM domain protein BZ172_09130 ENOG4105XFK Ferrous iron transport protein A BZ172_09135 ENOG4105CE1 Ferrous iron transport protein b BZ172_09150 ENOG4105DNE Transposase BZ172_09170 ENOG4105DNE Transposase BZ172_09180 ENOG4105MJ2 Competence protein BZ172_09190 ENOG4105C6Z Gluconate BZ172_09195 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) BZ172_09200 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) BZ172_09215 ENOG4105E0Y RtcB Protein BZ172_09245 ENOG4105E8Q phosphopantetheinyl transferase BZ172_09255 ENOG4105C7N Xanthine uracil vitamin C permease BZ172_09260 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 BZ172_09285 ENOG4107VKM 6-phosphogluconolactonase BZ172_09290 ENOG4106611 bacteriocin immunity BZ172_09310 ENOG4107VKM 6-phosphogluconolactonase BZ172_09315 ENOG4105DYC esterase BZ172_09325 ENOG4105VNT transposase (IS4 family) protein BZ172_09335 ENOG4105CA0 peroxidase BZ172_09340 ENOG4105CVK Glutamate decarboxylase BZ172_09345 ENOG4108NKV transcriptional regulator BZ172_09350 ENOG4105D3F AraC Family Transcriptional Regulator BZ172_09360 ENOG4105BZS acriflavin resistance protein BZ172_09365 ENOG4105C1P efflux transporter, rnd family, mfp subunit BZ172_09375 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci BZ172_09380 ENOG4108YK4 Acid-resistance membrane protein BZ172_09385 ENOG41060V2 Acid-resistance protein BZ172_09390 ENOG4105XXV Acid-resistance protein BZ172_09395 ENOG4105KT7 mgtC SapB transporter BZ172_09410 ENOG4105Y4Z Outer Membrane Lipoprotein BZ172_09435 ENOG4108MVM Transposase BZ172_09445 ENOG4108ZQS transposase BZ172_09480 ENOG4108MVM Transposase BZ172_09485 ENOG4108ZQS transposase BZ172_09565 ENOG4105DUU IucA IucC family protein BZ172_09570 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) BZ172_09630 ENOG4105DQ6 Transposase BZ172_09660 ENOG4105D01 (LipO)protein BZ172_09675 ENOG4105T8A Uncharacterized protein YicS BZ172_09690 ENOG4108SAJ Protein of unknown function (DUF1198) BZ172_09715 ENOG4105C7N Xanthine uracil vitamin C permease BZ172_09725 ENOG4105CXY transporter BZ172_09730 ENOG4105CXY transporter BZ172_09735 ENOG4105BZU Histidine kinase BZ172_09740 ENOG4108KX4 response regulator BZ172_09745 ENOG4105M71 acetolactate synthase 1 regulatory subunit BZ172_09750 ENOG4105C7K acetolactate synthase BZ172_09780 ENOG4105E5M Multidrug resistance protein D BZ172_09785 ENOG4105J13 transcriptional regulator BZ172_09790 ENOG4105JP4 Inner membrane protein yidG BZ172_09795 ENOG4105VG5 Membrane BZ172_09800 ENOG4106DRA Inner membrane protein YidI BZ172_09815 ENOG4105D7V transposase BZ172_09830 ENOG4105F8D glycoside hydrolase family 4 BZ172_09835 ENOG4105F8D glycoside hydrolase family 4 BZ172_09840 ENOG4105CI1 PTS System BZ172_09845 ENOG4105FDP GntR family transcriptional regulator BZ172_09870 ENOG4105R2A (LipO)protein BZ172_09875 ENOG4105D99 atp gtp-binding protein BZ172_09885 ENOG4105DJB Major Facilitator Superfamily BZ172_09895 ENOG4108RTU Aldolase BZ172_09900 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 BZ172_09905 ENOG4105EMF GntR family transcriptional regulator BZ172_09915 ENOG410667J hydrolase BZ172_09920 ENOG4105VP5 Bacterial protein of unknown function (DUF937) BZ172_09925 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ172_09935 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BZ172_09985 ENOG4105CYB regulatoR BZ172_09995 ENOG4105E98 transcriptional regulator DeoR family BZ172_10000 ENOG4105EBW Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity) BZ172_10010 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BZ172_10035 ENOG4105VNT transposase (IS4 family) protein BZ172_10040 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) BZ172_10065 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BZ172_10070 ENOG41076UM multiple antibiotic resistance (MarC)-related protein BZ172_10100 ENOG4105C6Z Gluconate BZ172_10105 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family BZ172_10110 ENOG4105DIQ Transcriptional regulator BZ172_10115 ENOG4105C2I pirin domain protein BZ172_10120 ENOG4105D9R oxidoreductase BZ172_10125 ENOG4105WCN acetyltransferase BZ172_10145 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BZ172_10150 ENOG4105WC8 Conserved Protein BZ172_10155 ENOG4107T6V glycerophosphoryl diester phosphodiesterase BZ172_10165 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BZ172_10170 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component BZ172_10175 ENOG4105BZ7 extracellular solute-binding protein family 1 BZ172_10180 ENOG4108IV0 ABC, transporter BZ172_10185 ENOG4105C0Z ABC transporter BZ172_10190 ENOG4105CF8 branched-chain amino acid ABC transporter, permease BZ172_10195 ENOG4105C32 Amino acid ABC transporter (Permease) BZ172_10200 ENOG4105CP9 extracellular ligand-binding receptor BZ172_10210 ENOG4105U59 -acetyltransferase BZ172_10215 ENOG4105CP9 extracellular ligand-binding receptor BZ172_10220 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ172_10225 ENOG4105CRP Part of the ABC transporter FtsEX involved in BZ172_10230 ENOG4105CAK Cell division ATP-binding protein ftsE BZ172_10235 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BZ172_10240 ENOG4106H78 methyltransferase BZ172_10245 ENOG4105MG3 Membrane BZ172_10255 ENOG4107FS9 Membrane BZ172_10270 ENOG4105EX9 Membrane BZ172_10275 ENOG4108W1V Lipoprotein BZ172_10280 ENOG4105F9N Major Facilitator Superfamily BZ172_10285 ENOG4105DSF transport protein BZ172_10290 ENOG4107YAK holo-(acyl carrier protein) synthase 2 BZ172_10295 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BZ172_10300 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BZ172_10305 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ172_10335 ENOG4105CMI transporter BZ172_10340 ENOG4105CJ1 ABC, transporter BZ172_10345 ENOG4105D0S secretion protein (HlyD BZ172_10370 ENOG4107UNS conserved inner membrane protein BZ172_10375 ENOG4105CBX hi0933 family BZ172_10380 ENOG4105CJ3 phosphate transporter BZ172_10390 ENOG4108M6U Universal stress protein A BZ172_10400 ENOG4105DUX Transporter BZ172_10410 ENOG4105DGW oligopeptidase A BZ172_10415 ENOG4105D6S protein involved in catabolism of external DNA BZ172_10420 ENOG4105DC8 reductase BZ172_10435 ENOG4105KBH arsR family transcriptional regulator BZ172_10440 ENOG4107R5R arsenical pump membrane protein BZ172_10445 ENOG4105K89 arsenate reductase BZ172_10470 ENOG4108MVM Transposase BZ172_10485 ENOG4105DFP Integrase BZ172_10495 ENOG4105CT4 transporter BZ172_10515 ENOG4105CT4 transporter BZ172_10520 ENOG4105CJQ hydrolase, family 31 BZ172_10525 ENOG4105VNT transposase (IS4 family) protein BZ172_10545 ENOG4105JV1 AsmA family BZ172_10550 ENOG4105C2W permease BZ172_10555 ENOG4105D6U Sodium Glutamate Symporter BZ172_10560 ENOG4105CB5 ATP-dependent DNA helicase recG BZ172_10565 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase BZ172_10570 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BZ172_10575 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) BZ172_10580 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) BZ172_10590 ENOG4105EN6 Membrane BZ172_10595 ENOG4105F5P DNA-damage-inducible protein d BZ172_10600 ENOG4105DSJ YicC domain protein BZ172_10630 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BZ172_10665 ENOG4105W0E 50S ribosomal protein L33 BZ172_10680 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase BZ172_10685 ENOG4105DKP glycosyl transferase, family 9 BZ172_10690 ENOG4107RJ7 Glycosyl transferase (Group 1 BZ172_10695 ENOG4107543 (lipo)polysaccharide BZ172_10700 ENOG4106AH0 Glycosyl Transferase BZ172_10705 ENOG4105X1N Glycosyl transferase family 8 BZ172_10715 ENOG4105X1N Glycosyl transferase family 8 BZ172_10720 ENOG4105K64 Glycosyl transferase, family 2 BZ172_10725 ENOG41068PG O-Antigen polymerase BZ172_10730 ENOG4105D16 lipopolysaccharide heptosyltransferase i BZ172_10735 ENOG4105XA0 heptosyltransferase ii BZ172_10745 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BZ172_10755 ENOG4105K64 Glycosyl transferase, family 2 BZ172_10780 ENOG4105PXI polysaccharide deacetylase BZ172_10785 ENOG41063SB peptidase BZ172_10800 ENOG4107YZP Rhodanese domain protein BZ172_10805 ENOG4105VW4 glutaredoxin 3 BZ172_10820 ENOG4105D7W serine acetyltransferase BZ172_10825 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BZ172_10835 ENOG41073TP transcriptional regulator BZ172_10840 ENOG4105DAA L-lactate BZ172_10850 ENOG4105EUR Domain-Containing protein BZ172_10855 ENOG4108WY4 inner membrane lipoprotein BZ172_10865 ENOG4108YYI Protein of unknown function (DUF2810) BZ172_10875 ENOG4105E61 Mannitol repressor protein BZ172_10885 ENOG4105CTS PTS system mannitol-specific BZ172_10890 ENOG4105FP6 Protein of unknown function (DUF3302) BZ172_10895 ENOG4105F5W AtP-binding protein BZ172_10900 ENOG4105D70 Integrase catalytic subunit BZ172_10905 ENOG4105EFX secretion protein, HlyD family BZ172_10920 ENOG4108U78 Glutathione S-transferase BZ172_10930 ENOG4105EM7 Selenocysteine-specific translation elongation factor BZ172_10960 ENOG410688U Inner membrane protein yiaB BZ172_10965 ENOG4108Z12 YiaAB two helix domain-containing protein BZ172_10970 ENOG4108MVM Transposase BZ172_10980 ENOG4108ZQS transposase BZ172_11000 ENOG4108Z12 YiaAB two helix domain-containing protein BZ172_11005 ENOG4105MEV Acyl-transferase BZ172_11015 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit BZ172_11025 ENOG41060TC Hok gef cell toxic protein BZ172_11030 ENOG4105VEQ Cold shock protein BZ172_11035 ENOG4105MVF Transcriptional regulator BZ172_11040 ENOG4106JH6 (LipO)protein BZ172_11050 ENOG4108ZG0 Ompa motb domain protein BZ172_11065 ENOG4107QY8 reductase BZ172_11070 ENOG4105HNP -acetyltransferase BZ172_11075 ENOG4108R3E Dna-3-methyladenine glycosylase i BZ172_11080 ENOG4105EAX Putative lipase BZ172_11090 ENOG4105FCD Major Facilitator BZ172_11095 ENOG4105DIJ Phosphoethanolamine transferase BZ172_11120 ENOG4105DEF Extracellular solute-binding protein, family 5 BZ172_11130 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BZ172_11135 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ172_11140 ENOG4105C3U ABC transporter BZ172_11145 ENOG4108JQ7 (ABC) transporter BZ172_11150 ENOG4105C44 Serine transporter BZ172_11215 ENOG4105D1V cellulose synthase operon protein YhjU BZ172_11220 ENOG4105WQA Cellulose biosynthesis protein BcsF BZ172_11225 ENOG4105U74 cellulose biosynthesis protein BcsE BZ172_11245 ENOG410661M cytoplasmic protein BZ172_11255 ENOG4107QZ7 Cellulose synthase catalytic subunit BZ172_11260 ENOG4107QZ7 Cellulose synthase catalytic subunit BZ172_11265 ENOG4107EEX Cellulose synthase regulator protein BZ172_11270 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) BZ172_11280 ENOG4105BZU Histidine kinase BZ172_11300 ENOG4105CS0 peptidase BZ172_11315 ENOG4105CMB EAL domain-containing protein BZ172_11320 ENOG41066T0 asmA family BZ172_11325 ENOG4105CSH Transporter BZ172_11330 ENOG4107H3J ribonuclease BZ172_11335 ENOG4105CBN LysR family transcriptional regulator BZ172_11340 ENOG4106S2D Transcriptional regulator BZ172_11345 ENOG4105VNT transposase (IS4 family) protein BZ172_11355 ENOG4105EV2 VWA domain protein interacting with AAA ATPase BZ172_11365 ENOG4108VVK transcriptional Regulator, AsnC BZ172_11370 ENOG4105QTB Flavodoxin BZ172_11385 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation BZ172_11395 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BZ172_11440 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BZ172_11520 ENOG4105VNT transposase (IS4 family) protein BZ172_11525 ENOG4108RQP Major type 1 subunit fimbrin BZ172_11545 ENOG4108NAE Fimbrial chaperone protein BZ172_11565 ENOG4105CW0 outer membrane usher protein BZ172_11575 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) BZ172_11580 ENOG4105C8U phosphate abc transporter BZ172_11585 ENOG4105E2Z phosphate ABC transporter (Permease BZ172_11590 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BZ172_11595 ENOG4108UTW Plays a role in the regulation of phosphate uptake BZ172_11600 ENOG4105CID antiterminator BZ172_11605 ENOG4105C5Y PTS System BZ172_11625 ENOG4105CS2 ec 3.2.1.21 BZ172_11635 ENOG4105DYC esterase BZ172_11640 ENOG4105VNT transposase (IS4 family) protein BZ172_11660 ENOG4105CNN ABC, transporter BZ172_11670 ENOG4108RVA ribokinase BZ172_11675 ENOG4105ETE Transcriptional regulator (LacI family BZ172_11680 ENOG4105C0R drug resistance transporter emrb qaca subfamily BZ172_11685 ENOG4107EJG GntR family transcriptional regulator BZ172_11725 ENOG4108WFC UPF0438 protein yifE BZ172_11745 ENOG4105C0P Mg chelatase subunit ChlI BZ172_11780 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit BZ172_11785 ENOG4105CM2 brancheD-chain amino acid aminotransferase BZ172_11795 ENOG4105C7B Threonine dehydratase BZ172_11800 ENOG4105EMY transcriptional regulator BZ172_11810 ENOG4105KQ5 peptidylprolyl cis-trans isomerase BZ172_11820 ENOG4108MVM Transposase BZ172_11830 ENOG4108ZQS transposase BZ172_11845 ENOG4105C4R Atp-dependent dna helicase BZ172_11865 ENOG4105K63 Thioredoxin BZ172_11885 ENOG4105ESV Glycosyl transferase, family 4 BZ172_11890 ENOG4105SFE lipopolysaccharide biosynthesis protein BZ172_11895 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BZ172_11900 ENOG4108IJ1 Dehydrogenase BZ172_11905 ENOG4105C1B dTDP-glucose 4-6-dehydratase BZ172_11910 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BZ172_11915 ENOG4108WJ1 acetyltransferase BZ172_11920 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BZ172_11925 ENOG4105EGZ biosynthesis protein BZ172_11945 ENOG4105C85 amino acid BZ172_11970 ENOG4105C4X radical SAM domain protein BZ172_11975 ENOG4105ENH Sulfatase BZ172_11980 ENOG410601J HemY protein BZ172_11990 ENOG41076E6 Uroporphyrinogen-III Synthase BZ172_12005 ENOG4107T0K Adenylate cyclase BZ172_12020 ENOG4105S7Z (LipO)protein BZ172_12030 ENOG4105CT0 Protein of unknown function, DUF484 BZ172_12040 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant BZ172_12045 ENOG4105C4R Atp-dependent dna helicase BZ172_12050 ENOG4107V4F S-adenosyl-l-methionine hydroxide adenosyltransferase BZ172_12055 ENOG4108T58 Mg2 transport protein CorA BZ172_12060 ENOG4105VNT transposase (IS4 family) protein BZ172_12075 ENOG4108T58 Mg2 transport protein CorA BZ172_12085 ENOG4107QUT magnesium and cobalt transport protein CorA BZ172_12120 ENOG4107QUT magnesium and cobalt transport protein CorA BZ172_12135 ENOG4105FR1 rard protein BZ172_12140 ENOG4108VUY thioesterase Superfamily protein BZ172_12145 ENOG4105HDD phospholipase BZ172_12150 ENOG4105C9U ATP-dependent DNA helicase RecQ BZ172_12165 ENOG4108EUD Lysophospholipase BZ172_12170 ENOG4105DQF Hydrolase BZ172_12175 ENOG4105EMK carboxylate amino acid amine transporter BZ172_12180 ENOG4105DZ2 Transcriptional regulator BZ172_12200 ENOG4108ZQS transposase BZ172_12225 ENOG4105GMB type VI secretion system effector, hcp1 family BZ172_12230 ENOG4105GMB type VI secretion system effector, hcp1 family BZ172_12235 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) BZ172_12240 ENOG4108I5U Uridine phosphorylase BZ172_12250 ENOG4105CGY Dna recombination protein BZ172_12260 ENOG4105JC1 sterol-binding domain protein BZ172_12270 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BZ172_12275 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) BZ172_12280 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BZ172_12285 ENOG4105F8V Hydrolase, tatD family BZ172_12290 ENOG4105MDZ Transcriptional activator rfaH BZ172_12295 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) BZ172_12300 ENOG4107QK7 reductase BZ172_12320 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BZ172_12325 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) BZ172_12330 ENOG4108RR8 protoporphyrinogen oxidase BZ172_12360 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b BZ172_12365 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) BZ172_12370 ENOG4105PC1 Conserved Protein BZ172_12375 ENOG4105E27 serine threonine protein kinase BZ172_12380 ENOG4108Z33 Thiol disulfide Interchange Protein BZ172_12405 ENOG4106HNH Acyl-transferase BZ172_12415 ENOG4105C2M dna polymerase I BZ172_12430 ENOG4105ZR3 A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity) BZ172_12435 ENOG4105D4P Coproporphyrinogen iii oxidase BZ172_12440 ENOG4106FIY BZ172_12445 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BZ172_12450 ENOG4105CUX Signal transduction histidine kinase BZ172_12455 ENOG4105C5F glutamine synthetase BZ172_12470 ENOG4105VNT transposase (IS4 family) protein BZ172_12475 ENOG4105E98 transcriptional regulator DeoR family BZ172_12480 ENOG4108MGF sugar kinase BZ172_12485 ENOG4105VNT transposase (IS4 family) protein BZ172_12490 ENOG4108MGF sugar kinase BZ172_12495 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BZ172_12500 ENOG4105D2M Aldolase BZ172_12505 ENOG4105CPQ Dehydrogenase BZ172_12515 ENOG4105CSH Transporter BZ172_12525 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 BZ172_12540 ENOG4105SUU thioesterase domain BZ172_12555 ENOG41068KX affects formate dehydrogenase-N BZ172_12570 ENOG4108MG3 formate dehydrogenase BZ172_12575 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein BZ172_12595 ENOG4108V87 frv operon regulatory protein BZ172_12610 ENOG4108V87 frv operon regulatory protein BZ172_12615 ENOG4106C3V frv operon regulatory protein BZ172_12620 ENOG4105CN9 Peptidase m42 family protein BZ172_12625 ENOG4105DM4 PTS System BZ172_12630 ENOG41064BA PTS system, fructose-specific, IIA component BZ172_12675 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BZ172_12695 ENOG4108RPX mosc domain containing protein BZ172_12700 ENOG4105E0F Histidine kinase BZ172_12705 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ172_12710 ENOG4105FMW periplasmic BZ172_12725 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein BZ172_12745 ENOG4105EBK exported protein BZ172_12750 ENOG4108VTS Membrane BZ172_12755 ENOG41065TG regulatoR BZ172_12765 ENOG4105DP0 ferredoxin-NADP reductase BZ172_12770 ENOG4105CBT Fructose-1,6-bisphosphatase BZ172_12780 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BZ172_12795 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BZ172_12800 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) BZ172_12810 ENOG41063M6 Cell Division Protein BZ172_12815 ENOG4105ETE Transcriptional regulator (LacI family BZ172_12820 ENOG4105C25 Primosomal protein n' BZ172_12835 ENOG4105CNA YD repeat protein BZ172_12855 ENOG4105CNA YD repeat protein BZ172_12855 ENOG4105CNA YD repeat protein BZ172_12880 ENOG4107S01 Repressor protein MetJ BZ172_12895 ENOG4105C28 cystathionine BZ172_12900 ENOG4105CFH Aspartokinase BZ172_12910 ENOG4105SYT Methylenetetrahydrofolate reductase BZ172_12920 ENOG4108Q5Y Membrane BZ172_12925 ENOG4108XC3 NADH ubiquinone oxidoreductase BZ172_12930 ENOG4105DCT glycerol dehydrogenase BZ172_12935 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BZ172_12940 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BZ172_12945 ENOG4105DM4 PTS System BZ172_12960 ENOG4108AHH pyruvate formate lyase II activase BZ172_12965 ENOG4108XCZ PTS System BZ172_12970 ENOG4106R3P AraC family transcriptional regulator BZ172_12975 ENOG4105DIJ Phosphoethanolamine transferase BZ172_12990 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase BZ172_13005 ENOG4105C5Q Transcriptional regulator BZ172_13015 ENOG4105EJ2 Transcriptional regulator BZ172_13020 ENOG4108Y73 Membrane BZ172_13035 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BZ172_13060 ENOG4105D4A Cell wall formation (By similarity) BZ172_13065 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase BZ172_13110 ENOG4105PM1 preprotein translocase subunit SecE BZ172_13115 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BZ172_13155 ENOG4105D41 biosynthesis protein thiH BZ172_13165 ENOG4105WHD thiamine biosynthesis protein ThiS BZ172_13170 ENOG4105D06 uba thif-type nad fad binding protein BZ172_13205 ENOG4105R2J Conserved Protein BZ172_13210 ENOG4105K70 DNA-binding protein BZ172_13215 ENOG4108T8B Protein of unknown function (DUF1481) BZ172_13220 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism BZ172_13230 ENOG4105BZU Histidine kinase BZ172_13235 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BZ172_13240 ENOG4105C12 Phosphoribosylglycinamide synthetase BZ172_13270 ENOG4105K5X acetyltransferase BZ172_13280 ENOG4107QP3 malate synthase g BZ172_13285 ENOG4107QP3 malate synthase g BZ172_13290 ENOG4108I9X Isocitrate lyase BZ172_13315 ENOG41069M3 Transcriptional regulator BZ172_13320 ENOG4105C3R Methionine synthase BZ172_13325 ENOG4105EAM Na Pi-cotransporter BZ172_13340 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein BZ172_13345 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein BZ172_13350 ENOG4105F3R pts system mannose fructose sorbose family iid BZ172_13355 ENOG4105ETZ PTS System BZ172_13365 ENOG4108XCU pts system BZ172_13370 ENOG4105CHR reductase BZ172_13375 ENOG4105DKT Transcriptional regulator BZ172_13380 ENOG4105DKT Transcriptional regulator BZ172_13385 ENOG4105DKT Transcriptional regulator BZ172_13390 ENOG4105FE9 pseudouridine synthase BZ172_13395 ENOG4108ZR5 Conserved Protein BZ172_13400 ENOG4105CFH Aspartokinase BZ172_13420 ENOG4108MDC (LipO)protein BZ172_13425 ENOG4108Q9C Periplasmic Protein BZ172_13430 ENOG4105E3R (LipO)protein BZ172_13450 ENOG4107QNK )-transporter BZ172_13455 ENOG4105EG2 ABC transporter, permease BZ172_13460 ENOG4105D56 permease protein BZ172_13465 ENOG4107FKK extracellular solute-binding protein family 1 BZ172_13475 ENOG4108IJ9 (ABC) transporter BZ172_13485 ENOG4107W52 maltose operon periplasmic protein BZ172_13500 ENOG4105EQR Transposase IS116 IS110 IS902 BZ172_13545 ENOG41080IJ Diacylglycerol kinase BZ172_13555 ENOG4107R73 Mate efflux family protein BZ172_13560 ENOG4105VDW Csbd family BZ172_13565 ENOG4105MYN Zinc uptake regulation protein BZ172_13580 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BZ172_13585 ENOG4105P4Z Phage shock protein G BZ172_13590 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BZ172_13595 ENOG4105CDU Replicative dna helicase BZ172_13605 ENOG4105CGF Aromatic amino acid aminotransferase BZ172_13615 ENOG4105F0S class B acid phosphatase BZ172_13620 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme BZ172_13625 ENOG4105MSB protein, conserved in bacteria BZ172_13630 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BZ172_13640 ENOG4108UUM single-stranded DNA-binding protein BZ172_13655 ENOG4108M8H domain protein BZ172_13660 ENOG4108W3Q Transcriptional regulator BZ172_13685 ENOG4105EEQ Na H antiporter BZ172_13690 ENOG4105C7N Xanthine uracil vitamin C permease BZ172_13710 ENOG4108Z4X TRANSCRIPTIONal BZ172_13735 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BZ172_13750 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit BZ172_13755 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein BZ172_13760 ENOG4105DVI reductase, NrfD BZ172_13765 ENOG4108QKW cytochrome c-type biogenesis protein BZ172_13775 ENOG4108W0S formate-dependent nitrite reductase complex BZ172_13785 ENOG4105CK2 sodium dicarboxylate symporter BZ172_13790 ENOG41082ND Uncharacterized protein yjcO BZ172_13800 ENOG4105ETP RND efflux system, outer membrane lipoprotein BZ172_13805 ENOG4108MI0 Resistance protein BZ172_13810 ENOG4105J12 Multidrug resistance protein mdtN BZ172_13820 ENOG4105EUZ Beta-lactamase domain protein BZ172_13825 ENOG4108YZG isomerase BZ172_13830 ENOG4106ZVZ Escherichia coli IMT2125 genomic chromosome, IMT2125 BZ172_13835 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein BZ172_13840 ENOG410849A acetyltransferase, (GNAT) family BZ172_13845 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) BZ172_13850 ENOG4105FD8 phosphonate metabolism protein PhnM BZ172_13855 ENOG4105HRV phosphonate c-p lyase system protein phnl BZ172_13860 ENOG4105ENV phosphonate C-P lyase system protein PhnK BZ172_13865 ENOG4105FT8 Phosphonate metabolism BZ172_13870 ENOG4105EKV Phosphonate metabolism protein BZ172_13875 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH BZ172_13880 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG BZ172_13885 ENOG4107RJJ Transcriptional regulator BZ172_13900 ENOG4105EHI Phosphonate ABC transporter, periplasmic BZ172_13910 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase BZ172_13915 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BZ172_13925 ENOG4108F5E vimentin BZ172_13930 ENOG4108YIV BZ172_13935 ENOG4105CSH Transporter BZ172_13945 ENOG4105ECM Sensor protein basS pmrB BZ172_13950 ENOG4105XJC Two component transcriptional regulator (Winged helix family BZ172_13955 ENOG4105DIJ Phosphoethanolamine transferase BZ172_13960 ENOG4105D5Q Arginine ornithine antiporter BZ172_13965 ENOG4106ZGR Transcriptional regulator BZ172_13970 ENOG4105CXN decarboxylase BZ172_13975 ENOG4108K2B transcriptional regulator BZ172_13985 ENOG4105F8D glycoside hydrolase family 4 BZ172_13990 ENOG4105CT4 transporter BZ172_14000 ENOG4108ZQS transposase BZ172_14010 ENOG4108MVM Transposase BZ172_14030 ENOG4108R5S membrane BZ172_14035 ENOG4107GFK fumarate BZ172_14040 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BZ172_14050 ENOG4108MRH transcriptional regulatory protein BZ172_14055 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BZ172_14060 ENOG4105VR1 Pfam:DUF1271 BZ172_14065 ENOG410830R acetyltransferase BZ172_14085 ENOG4105CRK lysyL-tRNA synthetase BZ172_14090 ENOG4105DUX Transporter BZ172_14095 ENOG4105CXN decarboxylase BZ172_14115 ENOG4108MVM Transposase BZ172_14125 ENOG4108ZQS transposase BZ172_14140 ENOG4105D5Q Arginine ornithine antiporter BZ172_14155 ENOG4105VNT transposase (IS4 family) protein BZ172_14160 ENOG4105D5Q Arginine ornithine antiporter BZ172_14180 ENOG4108SIC Transcriptional regulator BZ172_14195 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BZ172_14200 ENOG4108IJ0 Aspartate ammonia-lyase BZ172_14205 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 BZ172_14210 ENOG4105DVH amino acid BZ172_14225 ENOG4108ZVF (LipO)protein BZ172_14230 ENOG4105MTB Uncharacterized protein YjeJ BZ172_14245 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BZ172_14255 ENOG4106HKS Entericidin EcnA/B family BZ172_14260 ENOG4106BSU Entericidin B BZ172_14265 ENOG4105KPY Small multidrug resistance protein BZ172_14270 ENOG4105QNF Outer membrane lipoprotein BZ172_14275 ENOG41066YJ Beta-lactamase BZ172_14290 ENOG4105E33 succinate dehydrogenase BZ172_14295 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) BZ172_14305 ENOG4107SC7 Inner membrane transporter yjeM BZ172_14325 ENOG4107SC7 Inner membrane transporter yjeM BZ172_14330 ENOG4105EGS Mechanosensitive ion channel BZ172_14370 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) BZ172_14375 ENOG4105K8N protein family UPF0079, ATPase BZ172_14380 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BZ172_14395 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BZ172_14400 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BZ172_14405 ENOG4107QJR hflk protein BZ172_14410 ENOG4105EPW hflc protein BZ172_14430 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BZ172_14435 ENOG4105C2N RNA methyltransferase TrmH family group 3 BZ172_14455 ENOG4108KXT Conserved Protein BZ172_14460 ENOG4106032 Glutathionylspermidine synthase BZ172_14465 ENOG4105CSU acyl-Coa dehydrogenase BZ172_14470 ENOG4105S17 UPF0379 protein yjfN BZ172_14475 ENOG4105WSB biofilm stress and motility protein A BZ172_14480 ENOG4108MXZ Esterase BZ172_14525 ENOG4105R3P Inner membrane protein yagU BZ172_14550 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) BZ172_14560 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit BZ172_14565 ENOG4105CG6 trap dicarboxylate transporter dctm subunit BZ172_14590 ENOG4105FHY Opacity-associated protein A BZ172_14600 ENOG4108V1T peptidylprolyl cis-trans isomerase BZ172_14605 ENOG4105C85 amino acid BZ172_14615 ENOG4105DXC membrane BZ172_14620 ENOG4105ECR NmrA family BZ172_14625 ENOG4105KVH Transcriptional regulator BZ172_14630 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic BZ172_14635 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase BZ172_14650 ENOG4108UUE Transcriptional regulator BZ172_14655 ENOG41061GZ Protein of unknown function (DUF1107) BZ172_14660 ENOG4105C37 (CBS) domain BZ172_14675 ENOG4105CFU surface antigen BZ172_14680 ENOG4105MA0 exported protein BZ172_14685 ENOG4108ZHD aig2 family BZ172_14690 ENOG4105F0N pyrophosphate phospho-hydrolase BZ172_14695 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator BZ172_14700 ENOG4105C2J ABC transporter BZ172_14705 ENOG4107R9N ABC transporter BZ172_14710 ENOG41062B0 ABC transporter, permease BZ172_14720 ENOG4105DFU Cell wall formation (By similarity) BZ172_14730 ENOG4105CMS peptidase U62, modulator of DNA gyrase BZ172_14740 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) BZ172_14745 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BZ172_14750 ENOG4105CG3 alpha amylase, catalytic region BZ172_14755 ENOG4105C5Y PTS System BZ172_14760 ENOG4105D4X repressor BZ172_14765 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic BZ172_14770 ENOG4105KME endoribonuclease L-psp BZ172_14785 ENOG41077AM PyrBI operon attenuator BZ172_14795 ENOG4108UQ8 endoribonuclease L-psp BZ172_14800 ENOG4105F6U Short-chain dehydrogenase reductase Sdr BZ172_14805 ENOG4108XFH Transcriptional regulator BZ172_14810 ENOG4105XEP YhcH YjgK YiaL family protein BZ172_14830 ENOG4105XEP YhcH YjgK YiaL family protein BZ172_14860 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) BZ172_14865 ENOG4108MJ3 acetyltransferase BZ172_14895 ENOG4108M3P Membrane BZ172_14900 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BZ172_14905 ENOG4105MYG DNA polymerase iii, chi subunit BZ172_14915 ENOG4108M8S permease YjgP YjgQ family protein BZ172_14920 ENOG4108K5H permease YjgP YjgQ family protein BZ172_14925 ENOG4105D7A ATP-binding protein BZ172_14930 ENOG4105K2J Transcriptional regulator BZ172_14935 ENOG4105C6Z Gluconate BZ172_14940 ENOG4105CHR reductase BZ172_14945 ENOG4105CPQ Dehydrogenase BZ172_14955 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family BZ172_14960 ENOG4105DQ4 alcohol dehydrogenase BZ172_15000 ENOG4105E0A ABC, transporter BZ172_15005 ENOG4108IHU transport system permease protein BZ172_15010 ENOG4105DQ5 transport system permease protein BZ172_15015 ENOG4108HUF Transporter BZ172_15020 ENOG4105GAV receptor BZ172_15025 ENOG4108S3W Anti-feci sigma factor, fecr BZ172_15030 ENOG4108SF5 RNA Polymerase BZ172_15035 ENOG4108MBK is1 orf2 BZ172_15090 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria BZ172_15120 ENOG4107EFN gluconate transport system permease 3 BZ172_15135 ENOG4105DEI Mannitol dehydrogenase BZ172_15145 ENOG4105C6F GntR Family Transcriptional Regulator BZ172_15180 ENOG410836F Transposase BZ172_15190 ENOG4105CKI cobalamin synthesis protein BZ172_15195 ENOG4105VCD cytoplasmic protein BZ172_15200 ENOG4105D22 carbon starvation protein BZ172_15205 ENOG4107UWN reductase BZ172_15210 ENOG4105EFA 4-hydroxyphenylacetate BZ172_15255 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase BZ172_15260 ENOG4105C26 Dehydrogenase BZ172_15265 ENOG4105ERH Fumarylacetoacetate hydrolase BZ172_15270 ENOG4108V8F Transcriptional regulator, MarR family BZ172_15285 ENOG410617M Transcriptional regulator BZ172_15290 ENOG4105CPQ Dehydrogenase BZ172_15300 ENOG4105RI1 glycoprotein receptor BZ172_15305 ENOG4106CVF DNA replication protein BZ172_15315 ENOG4107XM3 UPF0442 protein BZ172_15320 ENOG4105DWK Membrane BZ172_15345 ENOG4108T94 DNA-binding transcriptional activator BglJ BZ172_15350 ENOG4108819 ferric iron reductase BZ172_15355 ENOG4105YBH Protein of unknown function (DUF1435) BZ172_15380 ENOG4108WPU DNA polymerase III subunit psi BZ172_15385 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BZ172_15390 ENOG4105PAD Hydrolase BZ172_15400 ENOG4105K3G Periplasmic Protein BZ172_15410 ENOG4108NRW Phospholipase, patatin family BZ172_15415 ENOG4105EYA deoxyribonuclease BZ172_15425 ENOG41076CZ activating enzyme BZ172_15430 ENOG4105G0K glycine radical enzyme YjjI family BZ172_15470 ENOG4105EAC phosphoserine phosphatase BZ172_15475 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BZ172_15480 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase BZ172_15490 ENOG4105C5H ABC transporter BZ172_15500 ENOG4107SC1 transglycosylase BZ172_15510 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BZ172_15520 ENOG4105UEI Transcriptional Regulator AraC Family BZ172_15525 ENOG4108RH0 Crea protein BZ172_15530 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ172_15535 ENOG4105EB3 Histidine kinase BZ172_15540 ENOG4105CT7 inner membrane cred family protein BZ172_15545 ENOG41065U4 response regulator BZ172_15550 ENOG410759A BZ172_15555 ENOG4106FVC RNA methyltransferase BZ172_15565 ENOG4105CFH Aspartokinase BZ172_15575 ENOG4105D98 threonine synthase BZ172_15585 ENOG41062C6 Protein of unknown function (DUF2502) BZ172_15595 ENOG4105BZG amino acid carrier protein BZ172_15625 ENOG4108RIR Molybdenum cofactor biosynthesis protein BZ172_15630 ENOG4106HK8 GPR1 FUN34 yaaH family protein BZ172_15635 ENOG4108QUJ UPF0174 protein YaaW BZ172_15655 ENOG4105WI6 cell killing protein encoded within cryptic prophage BZ172_15685 ENOG41063Z6 transcriptional regulator, lysR family BZ172_15700 ENOG4105CW0 outer membrane usher protein BZ172_15735 ENOG410647N response to DNA damage stimulus BZ172_15740 ENOG4105DTN riboflavin biosynthesis protein ribF BZ172_15755 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase BZ172_15775 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BZ172_15780 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BZ172_15805 ENOG4108XNW Transcriptional activatory protein CaiF BZ172_15815 ENOG4106YT9 Enoyl-CoA hydratase BZ172_15860 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase BZ172_15865 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein BZ172_15885 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) BZ172_15910 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) BZ172_15920 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) BZ172_15925 ENOG4105D3G Pseudouridine synthase BZ172_15935 ENOG4105CQ2 DNA polymerase BZ172_15940 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BZ172_15960 ENOG41063TF transcriptional regulator (AraC BZ172_15965 ENOG4108KF1 Membrane BZ172_15975 ENOG4106SMU thiamine transporter membrane protein BZ172_15980 ENOG4105DP9 ABC transporter BZ172_15995 ENOG4105S8Q sugar efflux transporter BZ172_16040 ENOG41064T2 transcriptional regulator, lysR family BZ172_16045 ENOG4105C7K acetolactate synthase BZ172_16050 ENOG4108ZP8 Acetolactate synthase small subunit BZ172_16060 ENOG4107B7Y DNA-binding transcriptional regulator FruR BZ172_16095 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) BZ172_16100 ENOG4105CJN penicillin-binding protein BZ172_16105 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BZ172_16110 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) BZ172_16125 ENOG4105CNI cell division protein FtsW BZ172_16140 ENOG4105CPF Cell wall formation (By similarity) BZ172_16145 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) BZ172_16150 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BZ172_16155 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BZ172_16175 ENOG4105M6F mutator MutT protein BZ172_16190 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BZ172_16205 ENOG4107QHF type ii secretion system protein e BZ172_16210 ENOG4107QHF type ii secretion system protein e BZ172_16215 ENOG4108ZUW Major pilin subunit BZ172_16225 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BZ172_16230 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BZ172_16235 ENOG4106A72 regulatory protein AmpE BZ172_16240 ENOG4105C85 amino acid BZ172_16245 ENOG41073TP transcriptional regulator BZ172_16255 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) BZ172_16260 ENOG4107QSN dihydrolipoamide acetyltransferase BZ172_16265 ENOG4107QN2 dihydrolipoyl dehydrogenase BZ172_16270 ENOG4108NST exported protein BZ172_16280 ENOG4107QIJ Aconitate hydratase 2 BZ172_16300 ENOG4108ZRK uncharacterized protein yacC BZ172_16305 ENOG4105E3B Multicopper oxidase BZ172_16310 ENOG4105DZG Dehydrogenase BZ172_16315 ENOG4108UGV hypoxanthine phosphoribosyltransferase BZ172_16320 ENOG41077A9 carbonic anhydrase BZ172_16325 ENOG4105DA5 (ABC) transporter BZ172_16330 ENOG4105E3A (ABC) transporter BZ172_16335 ENOG4108YTN IIa component BZ172_16340 ENOG4107BJW polysaccharide deacetylase BZ172_16355 ENOG4108A32 Transposase BZ172_16375 ENOG4105P0Q fimbrial-like protein YadC BZ172_16405 ENOG4108ZQS transposase BZ172_16415 ENOG4108MVM Transposase BZ172_16425 ENOG4105SN2 fimbrial-like adhesin protein BZ172_16430 ENOG4105SYG Fimbrial protein BZ172_16435 ENOG4108XEY fimbrial-like adhesin protein BZ172_16440 ENOG4108MVM Transposase BZ172_16450 ENOG4108ZQS transposase BZ172_16465 ENOG4105CW0 outer membrane usher protein BZ172_16485 ENOG4108VEV chaperone BZ172_16495 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BZ172_16500 ENOG4105DJ0 Poly(A) Polymerase BZ172_16510 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters BZ172_16520 ENOG4107XID 2'-5' rna ligase BZ172_16525 ENOG4105CQ7 ATP-dependent helicase BZ172_16535 ENOG4105BZ4 penicillin-binding protein BZ172_16540 ENOG4105E0K tonB-dependent siderophore receptor BZ172_16545 ENOG4105E0A ABC, transporter BZ172_16550 ENOG4105J76 Periplasmic binding protein BZ172_16555 ENOG4105S6R Iron-hydroxamate transporter permease subunit BZ172_16575 ENOG4105EN6 Membrane BZ172_16580 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) BZ172_16615 ENOG4105C0H protease BZ172_16620 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR BZ172_16630 ENOG4105DIN metallophosphoesterase BZ172_16645 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BZ172_16680 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BZ172_16685 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BZ172_16690 ENOG4105KNE Phosphatidate cytidylyltransferase BZ172_16695 ENOG4105DZP Membrane-associated zinc metalloprotease BZ172_16705 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) BZ172_16710 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) BZ172_16735 ENOG4105C0B DNA polymerase III (alpha subunit) BZ172_16745 ENOG4105VNT transposase (IS4 family) protein BZ172_16750 ENOG4105CXN decarboxylase BZ172_16755 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BZ172_16760 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BZ172_16765 ENOG4105M1T rho-binding antiterminator BZ172_16775 ENOG4108VWS Yaeq family BZ172_16785 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion BZ172_16790 ENOG4108UY0 (LipO)protein BZ172_16800 ENOG4108R96 Methyltransferase, YaeB family BZ172_16805 ENOG4108R8X outer membrane lipoprotein BZ172_16810 ENOG4105D01 (LipO)protein BZ172_16815 ENOG4108UMI ABC transporter, permease BZ172_16820 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BZ172_16825 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BZ172_16860 ENOG4105CV8 reductase BZ172_16865 ENOG4105HEI LysR family (Transcriptional regulator BZ172_16875 ENOG4105F2W methyltransferase BZ172_16880 ENOG4105E9H Lytic Murein transglycosylase BZ172_16890 ENOG4105D1A Methyltransferase BZ172_16900 ENOG4107RZZ dna polymerase iii epsilon subunit BZ172_16910 ENOG410600K aminopeptidase BZ172_16925 ENOG4105GMB type VI secretion system effector, hcp1 family BZ172_16940 ENOG4108MVM Transposase BZ172_16950 ENOG4108ZQS transposase BZ172_17030 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ172_17040 ENOG4105CS6 Rhs element vgr protein BZ172_17045 ENOG4105CNA YD repeat protein BZ172_17055 ENOG410600T transposase BZ172_17060 ENOG410600T transposase BZ172_17075 ENOG410600T transposase BZ172_17080 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BZ172_17085 ENOG4108WN0 inhibitor of vertebrate lysozyme BZ172_17090 ENOG4107QPN acyl-Coa dehydrogenase BZ172_17100 ENOG4105E7A Glutamine amidotransferase BZ172_17105 ENOG4105F7V ErfK ybiS ycfS ynhG family protein BZ172_17110 ENOG4105VXN addiction module toxin, RelE StbE family BZ172_17120 ENOG4108YS0 lipoprotein YafL BZ172_17140 ENOG4108UK5 Transposase BZ172_17160 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BZ172_17165 ENOG4108HYG acetyltransferase BZ172_17180 ENOG410836F Transposase BZ172_17195 ENOG4108S2Y peptide Chain Release factor BZ172_17200 ENOG4105CIN aminoacyl-histidine dipeptidase BZ172_17220 ENOG4105FCK Membrane BZ172_17305 ENOG4105MI0 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity) BZ172_17315 ENOG4108K2P TRANSCRIPTIONal BZ172_17320 ENOG4108K2P TRANSCRIPTIONal BZ172_17325 ENOG4105ETE Transcriptional regulator (LacI family BZ172_17340 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) BZ172_17355 ENOG4105E82 cytochrome subunit of dehydrogenase BZ172_17400 ENOG4105DQ4 alcohol dehydrogenase BZ172_17405 ENOG4105DZC cytosine deaminase BZ172_17410 ENOG4105C5B carbamate kinase BZ172_17415 ENOG4107REC cytoplasmic protein BZ172_17420 ENOG4107R1Q Membrane protein FdrA BZ172_17425 ENOG4105N16 Protein of unknown function (DUF2877) BZ172_17430 ENOG4107SNB ankyrin repeat protein YahD BZ172_17450 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) BZ172_17455 ENOG4107QR9 Iron-sulfur cluster binding protein BZ172_17460 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BZ172_17465 ENOG4108K01 transcriptional regulator BZ172_17470 ENOG4107QN2 dihydrolipoyl dehydrogenase BZ172_17475 ENOG41066GK UPF0379 protein ykgI BZ172_17480 ENOG4108KBJ Inner membrane protein YkgB BZ172_17485 ENOG4105CV8 reductase BZ172_17490 ENOG4108MVM Transposase BZ172_17500 ENOG4108ZQS transposase BZ172_17535 ENOG4108SC4 )-transporter BZ172_17540 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme BZ172_17560 ENOG4105SRB Uncharacterized protein yaiO BZ172_17575 ENOG4107W19 lmbE family BZ172_17580 ENOG4108MVM Transposase BZ172_17590 ENOG4108ZQS transposase BZ172_17600 ENOG4106FTQ Taurine ABC transporter, periplasmic BZ172_17605 ENOG4108IY8 ABC, transporter BZ172_17610 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BZ172_17615 ENOG4105E2B Taurine dioxygenase BZ172_17620 ENOG4105D52 delta-aminolevulinic acid dehydratase BZ172_17635 ENOG4108PNB DNA-binding transcriptional regulator BZ172_17640 ENOG4107R6D beta-lactam binding protein AmpH BZ172_17650 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 BZ172_17655 ENOG4107QS8 (LipO)protein BZ172_17660 ENOG4105FR5 inner membrane protein YaiY BZ172_17665 ENOG4105UNH Membrane BZ172_17670 ENOG4105CPF Cell wall formation (By similarity) BZ172_17685 ENOG4105G6Z alkaline phosphatase BZ172_17690 ENOG4105VIF phosphate starvation-inducible protein BZ172_17695 ENOG4105BZU Histidine kinase BZ172_17715 ENOG4105II7 pyrroline-5-carboxylate reductase BZ172_17730 ENOG4105SS3 BZ172_17740 ENOG4105HBA AroM protein BZ172_17750 ENOG4105VNT transposase (IS4 family) protein BZ172_17775 ENOG4105DKQ ROK family BZ172_17780 ENOG4105F27 Major Facilitator BZ172_17785 ENOG4105EYH Exonuclease BZ172_17790 ENOG4107RH8 nuclease SbcCD subunit D BZ172_17795 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BZ172_17800 ENOG4105BZU Histidine kinase BZ172_17805 ENOG4105CWM branched-chain amino acid transport system II carrier protein BZ172_17810 ENOG4105C85 amino acid BZ172_17815 ENOG4107R28 alpha amylase, catalytic region BZ172_17835 ENOG4105VIE preprotein translocase, subunit YajC BZ172_17840 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BZ172_17845 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BZ172_17850 ENOG4105N1F Hnh endonuclease BZ172_17855 ENOG4105DRB nucleoside-specific channel-forming protein BZ172_17860 ENOG4108KIC (LipO)protein BZ172_17870 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BZ172_17875 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) BZ172_17885 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) BZ172_17890 ENOG4108ZAI phosphatidylglycerophosphatase a BZ172_17895 ENOG4105CPC Aldo Keto reductase BZ172_17905 ENOG4105CTB Polyprenyl synthetase BZ172_17920 ENOG4107S0N DJ-1 family BZ172_17925 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BZ172_17935 ENOG4107RDB Major Facilitator BZ172_17995 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) BZ172_18000 ENOG4105CCU oxidase (Subunit III) BZ172_18005 ENOG4105BZ9 Cytochrome C oxidase, subunit I BZ172_18010 ENOG4105E2S oxidase) subunit II BZ172_18015 ENOG4105EYM Major Facilitator superfamily BZ172_18020 ENOG4105IEY (LipO)protein BZ172_18025 ENOG4105M85 Bola protein BZ172_18050 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) BZ172_18055 ENOG4105K70 DNA-binding protein BZ172_18060 ENOG4105EIN peptidylprolyl cis-trans isomerase BZ172_18085 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein BZ172_18090 ENOG4108TGP Thioesterase superfamily protein BZ172_18100 ENOG4108NFA extracellular solute-binding protein BZ172_18110 ENOG4108XM1 transcriptional regulator AsnC family BZ172_18115 ENOG4105BZ1 (ABC) transporter BZ172_18120 ENOG4105BZ1 (ABC) transporter BZ172_18125 ENOG4108YZA Nitrogen regulatory protein pii BZ172_18130 ENOG4105BZU Histidine kinase BZ172_18135 ENOG4105C29 acyl-CoA thioesterase BZ172_18140 ENOG4108MNP Glycoprotein polysaccharide metabolism BZ172_18145 ENOG41080UX Methyltransferase BZ172_18155 ENOG4105KCV RNA signal recognition particle 4.5S RNA BZ172_18165 ENOG4105GSJ Inner membrane protein ylaC BZ172_18170 ENOG4108UW5 maltose o-acetyltransferase BZ172_18175 ENOG4105KF5 hemolysin expression-modulating protein BZ172_18180 ENOG4108UKR Biofilm formation regulator YbaJ BZ172_18185 ENOG4105BZS acriflavin resistance protein BZ172_18190 ENOG4105C1P efflux transporter, rnd family, mfp subunit BZ172_18195 ENOG4108IG5 Transcriptional regulator BZ172_18205 ENOG4105EGS Mechanosensitive ion channel BZ172_18215 ENOG4106428 Protein of unknown function (DUF2496) BZ172_18220 ENOG4108URS primosomal replication protein n'' BZ172_18225 ENOG4105WD1 Membrane BZ172_18240 ENOG4107QMP dna polymerase iii subunits gamma and tau BZ172_18255 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) BZ172_18275 ENOG4107RE1 Inosine-guanosine kinase BZ172_18280 ENOG4105CKD glutathione-regulated potassium-efflux system protein BZ172_18295 ENOG4105EU0 Major facilitator Superfamily BZ172_18305 ENOG4105CGH 5'-nucleotidase BZ172_18310 ENOG4108Z66 YbaK ebsC protein BZ172_18315 ENOG4105MBR gumn family BZ172_18320 ENOG41081XE plasmid maintenance system antidote protein, xre family BZ172_18330 ENOG4105C59 p-type ATPase BZ172_18335 ENOG4105CSV Glutaminase BZ172_18340 ENOG4107RY6 amino acid BZ172_18350 ENOG4108Z6Z Transcriptional regulator BZ172_18355 ENOG4105G5H Membrane BZ172_18360 ENOG4107QX8 SPFH domain, Band 7 family protein BZ172_18365 ENOG41083J0 (ABC) transporter BZ172_18370 ENOG4105C4B ABC transporter, permease BZ172_18375 ENOG4107QR8 Thioredoxin BZ172_18380 ENOG4105E1F short-chain dehydrogenase reductase BZ172_18385 ENOG4108UJV acyl-CoA thioesterase i BZ172_18390 ENOG4108I0Y (ABC) transporter BZ172_18395 ENOG4105CV6 ABC transporter, permease BZ172_18440 ENOG4105WQ3 Rna-binding protein BZ172_18455 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BZ172_18470 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BZ172_18475 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BZ172_18480 ENOG4105C5B carbamate kinase BZ172_18485 ENOG4105G5A Protein of unknown function (DUF2877) BZ172_18490 ENOG4107REC cytoplasmic protein BZ172_18505 ENOG4105DTE Xanthine uracil vitamin C permease BZ172_18515 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) BZ172_18545 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) BZ172_18550 ENOG4108ZI2 Fimbrial protein BZ172_18555 ENOG4108Q9V regulatoR BZ172_18560 ENOG4108ZQS transposase BZ172_18570 ENOG4108MVM Transposase BZ172_18605 ENOG4105QUW BZ172_18610 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit BZ172_18635 ENOG4105CNA YD repeat protein BZ172_18650 ENOG4105CS6 Rhs element vgr protein BZ172_18660 ENOG4105GR3 Histidine kinase BZ172_18665 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BZ172_18675 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BZ172_18680 ENOG410624V efflux system protein BZ172_18685 ENOG4105EP1 Efflux transporter rnd family, mfp subunit BZ172_18690 ENOG4108IJF Heavy metal efflux pump, CzcA BZ172_18695 ENOG4105C85 amino acid BZ172_18700 ENOG4105CUY Mechanosensitive ion channel BZ172_18705 ENOG4108RCM Nitroreductase BZ172_18710 ENOG4105MSB protein, conserved in bacteria BZ172_18735 ENOG4107635 Hok Gef family protein BZ172_18745 ENOG4107635 Hok Gef family protein BZ172_18750 ENOG4108TSE Transferase BZ172_18755 ENOG4107RNH Outer membrane receptor FepA BZ172_18765 ENOG4105E93 esterase BZ172_18770 ENOG41085A6 mbth domain-containing protein BZ172_18775 ENOG4105C0W non-ribosomal peptide synthetase BZ172_18780 ENOG4108QY5 Ferric enterobactin transport protein BZ172_18785 ENOG4105E0A ABC, transporter BZ172_18790 ENOG4105TVJ transport system, permease BZ172_18795 ENOG4105DQ5 transport system permease protein BZ172_18805 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein BZ172_18815 ENOG4105E4F Isochorismate synthase BZ172_18820 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BZ172_18825 ENOG4105WQI isochorismatase BZ172_18830 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BZ172_18840 ENOG4105D22 carbon starvation protein BZ172_18845 ENOG4105VCD cytoplasmic protein BZ172_18850 ENOG4107SCQ Iron-containing alcohol dehydrogenase BZ172_18855 ENOG4105CHM Aminotransferase BZ172_18860 ENOG4105GTN ParB Domain Protein Nuclease BZ172_18885 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase BZ172_18890 ENOG4105D3R alkyl hydroperoxide reductase BZ172_18895 ENOG4108JU3 Alkyl hydroperoxide reductase BZ172_18900 ENOG4108U51 Universal stress protein BZ172_18905 ENOG4105E2A Dehydrogenase BZ172_18915 ENOG4105NXH GreA GreB family elongation factor BZ172_18925 ENOG4105KTS ribonuclease BZ172_18930 ENOG4107QPK )-transporter BZ172_18945 ENOG4105CHY citrate lyase, alpha BZ172_18950 ENOG4105CI0 Citrate lyase BZ172_18960 ENOG4105DUA (citrate (pro-3S)-lyase ligase BZ172_18980 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BZ172_18985 ENOG4106YYS transcriptional regulatory protein BZ172_18990 ENOG4105CEE C4-dicarboxylate transporter BZ172_19010 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) BZ172_19015 ENOG4105VEQ Cold shock protein BZ172_19025 ENOG4107QPI nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BZ172_19030 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) BZ172_19035 ENOG4105VNT transposase (IS4 family) protein BZ172_19050 ENOG41064T2 transcriptional regulator, lysR family BZ172_19070 ENOG4105DZ1 carboxypeptidase BZ172_19075 ENOG4105K6T rare lipoprotein A BZ172_19080 ENOG4105CNI cell division protein FtsW BZ172_19085 ENOG4105CJN penicillin-binding protein BZ172_19095 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) BZ172_19100 ENOG4108TGR phosphatase BZ172_19110 ENOG4105DJF DNA polymerase III, delta' subunit BZ172_19125 ENOG4107PAI alpha helical protein BZ172_19130 ENOG4105EUU Sel1 domain protein repeat-containing protein BZ172_19135 ENOG41069CF Protein of unknown function (DUF1266) BZ172_19140 ENOG4105QFC Hsc56 co-chaperone of HscC BZ172_19145 ENOG4107JFD Sel1 repeat BZ172_19150 ENOG41069CF Protein of unknown function (DUF1266) BZ172_19155 ENOG4105QFC Hsc56 co-chaperone of HscC BZ172_19160 ENOG4105F7F Chaperone BZ172_19170 ENOG4105CDA abc transporter atp-binding protein BZ172_19175 ENOG4105DRP amino acid AbC transporter BZ172_19180 ENOG4105EAD ABC transporter BZ172_19185 ENOG4107RP9 extracellular solute-binding protein, family 3 BZ172_19200 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) BZ172_19205 ENOG4108JU5 Magnesium and cobalt efflux protein BZ172_19215 ENOG4105C9A Phoh family BZ172_19225 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BZ172_19275 ENOG4105CAQ asparagine synthetase BZ172_19295 ENOG4105D4U had-superfamily hydrolase, subfamily iia BZ172_19300 ENOG4105E2R ROK family BZ172_19305 ENOG4105CE4 GlcNAc 6-P deacetylase BZ172_19315 ENOG4105CI1 PTS System BZ172_19335 ENOG4105GX6 (LipO)protein BZ172_19340 ENOG41090R7 Ferric uptake BZ172_19355 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) BZ172_19360 ENOG4105NNH LexA regulated protein BZ172_19365 ENOG4105EV9 Alpha Beta Hydrolase BZ172_19370 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) BZ172_19375 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 BZ172_19380 ENOG4105D5Q Arginine ornithine antiporter BZ172_19385 ENOG4105CXN decarboxylase BZ172_19395 ENOG4105EEX Two component transcriptional regulator (Winged helix family BZ172_19400 ENOG4105C08 Histidine kinase BZ172_19425 ENOG4105XIQ Protein of unknown function (DUF2517) BZ172_19430 ENOG4105CNA YD repeat protein BZ172_19435 ENOG4105D70 Integrase catalytic subunit BZ172_19440 ENOG4105F5W AtP-binding protein BZ172_19465 ENOG4105CVP deoxyribo-dipyrimidine photolyase BZ172_19470 ENOG4107SEY Conserved Protein BZ172_19490 ENOG4105DUX Transporter BZ172_19495 ENOG4107QNR UPF0135 protein BZ172_19500 ENOG4105P4J Allophanate hydrolase, subunit 1 BZ172_19505 ENOG4107R7A Allophanate hydrolase subunit 2 BZ172_19520 ENOG4108KK1 membrane protein AbrB duplication BZ172_19525 ENOG4108MY7 Fimbrial BZ172_19530 ENOG4108TTM chaperone BZ172_19540 ENOG4106UBK fimbrial-like adhesin protein BZ172_19545 ENOG4105BZN citrate synthase BZ172_19565 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit BZ172_19570 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein BZ172_19575 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) BZ172_19580 ENOG4105E33 succinate dehydrogenase BZ172_19585 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 BZ172_19590 ENOG4105C7S Dehydrogenase BZ172_19600 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BZ172_19605 ENOG4105FDP GntR family transcriptional regulator BZ172_19610 ENOG4105DM4 PTS System BZ172_19625 ENOG4105C4M (Ubiquinol oxidase) subunit I BZ172_19630 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BZ172_19640 ENOG4105KJB cyd operon protein YbgE BZ172_19645 ENOG4107YD3 Thioesterase BZ172_19650 ENOG4105E02 MotA TolQ exbB proton channel BZ172_19655 ENOG4105M8F Biopolymer transport protein exbD tolR BZ172_19660 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA BZ172_19670 ENOG4105KCK Peptidoglycan-associated lipoprotein BZ172_19675 ENOG4105UFD tol-pal system protein YbgF BZ172_19730 ENOG4106Z1T Nicotinamide Mononucleotide Transporter BZ172_19735 ENOG4105PGM cation diffusion facilitator family transporter BZ172_19740 ENOG4105JND homeobox protein BZ172_19750 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BZ172_19760 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) BZ172_19765 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) BZ172_19770 ENOG4105F0Z galactose-1-phosphate uridylyltransferase BZ172_19775 ENOG4105CMR udp-glucose 4-epimerase BZ172_19780 ENOG4105DKW ABC transporter BZ172_19785 ENOG4105F4R Transcriptional regulator mode BZ172_19790 ENOG410680R Protein of unknown function (DUF2592) BZ172_19800 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BZ172_19805 ENOG4105E0C molybdate abc transporter BZ172_19810 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) BZ172_19815 ENOG4108K4B hydrolase BZ172_19820 ENOG4108I1J Integrase BZ172_19845 ENOG4105WI6 cell killing protein encoded within cryptic prophage BZ172_19850 ENOG4105WPN DNA integration recombination invertion protein BZ172_19865 ENOG4105JBR DNA replication protein BZ172_19895 ENOG41087BU transcriptional repressor DicA BZ172_19925 ENOG410836F Transposase BZ172_19935 ENOG4108MVM Transposase BZ172_19945 ENOG4108ZQS transposase BZ172_19950 ENOG4105KUS lysozyme BZ172_19955 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 BZ172_19970 ENOG4108N0N Phage Terminase Large Subunit BZ172_20015 ENOG4108C33 Resolvase BZ172_20025 ENOG4105F04 LysR family Transcriptional regulator BZ172_20045 ENOG4107QM5 aconitate hydratase BZ172_20050 ENOG4105NBR Pectinesterase BZ172_20055 ENOG4108I1J Integrase BZ172_20070 ENOG4108X9F tail fiber protein BZ172_20085 ENOG4108QHK Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway BZ172_20100 ENOG4108V1U phospholipid-binding protein BZ172_20105 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BZ172_20120 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BZ172_20125 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BZ172_20140 ENOG4105CHW UPF0052 protein BZ172_20150 ENOG4108RIR Molybdenum cofactor biosynthesis protein BZ172_20160 ENOG4105M00 molybdopterin converting factor, subunit 1 BZ172_20165 ENOG4108ZAF Molybdopterin BZ172_20170 ENOG4105HFZ Membrane BZ172_20185 ENOG4105DZQ phospholipase D Transphosphatidylase BZ172_20190 ENOG4105X23 Endonuclease Exonuclease phosphatase BZ172_20195 ENOG4105I9U inner membrane protein ybhQ BZ172_20200 ENOG4107QWP ABC-2 type transporter BZ172_20205 ENOG4107QWP ABC-2 type transporter BZ172_20210 ENOG4105CJ1 ABC, transporter BZ172_20220 ENOG4107MVR Transcriptional regulator BZ172_20225 ENOG4105C1J atp-dependent rna helicase BZ172_20245 ENOG4105DVT helicase BZ172_20250 ENOG4108MTB glycosyl transferase family BZ172_20255 ENOG4105DG4 malate L-lactate dehydrogenase BZ172_20260 ENOG4105VR4 UPF0379 protein ybiJ BZ172_20265 ENOG4105KSC Transcriptional regulator, TraR DksA family BZ172_20280 ENOG4105VNT transposase (IS4 family) protein BZ172_20285 ENOG4108ESX Receptor BZ172_20290 ENOG4105ZY9 UPF0379 protein ybiM BZ172_20300 ENOG4105D8X mechanosensitive ion channel BZ172_20310 ENOG4105CDA abc transporter atp-binding protein BZ172_20315 ENOG4105E5Q amino acid AbC transporter BZ172_20320 ENOG4107R0W ABC transporter BZ172_20340 ENOG4107AQZ Membrane BZ172_20345 ENOG4108T1M outer membrane protein x BZ172_20350 ENOG4108I6E Sulfatase BZ172_20360 ENOG4105KST dependent repressor BZ172_20365 ENOG4105F4P )-transporter BZ172_20370 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BZ172_20375 ENOG4105C5H ABC transporter BZ172_20385 ENOG4105DPW Major facilitator superfamily MFS_1 BZ172_20390 ENOG4105ETE Transcriptional regulator (LacI family BZ172_20395 ENOG41072TH Protein of unknown function (DUF1479) BZ172_20400 ENOG4108HCJ Hydrolase BZ172_20405 ENOG4105C6N Formate acetyltransferase BZ172_20410 ENOG4105F1A Pyruvate formate-lyase BZ172_20415 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BZ172_20420 ENOG4105D06 uba thif-type nad fad binding protein BZ172_20425 ENOG4105CVM Molybdenum cofactor synthesis domain protein BZ172_20430 ENOG4105D44 asparaginase BZ172_20450 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ172_20455 ENOG4105BZU Histidine kinase BZ172_20470 ENOG4105BZU Histidine kinase BZ172_20485 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway BZ172_20490 ENOG4105D8V Glucose sorbosone dehydrogenase BZ172_20495 ENOG4108TGY Glutathione S-transferase BZ172_20515 ENOG4107FB0 transcriptional regulator DeoR family BZ172_20520 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BZ172_20535 ENOG4108HCJ Hydrolase BZ172_20540 ENOG4106UW1 Major Facilitator superfamily BZ172_20545 ENOG4108RFG Tetr family transcriptional regulator BZ172_20555 ENOG4105GWF inner membrane protein YbjM BZ172_20560 ENOG41090BQ Glutaredoxin BZ172_20565 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress BZ172_20570 ENOG4108DBC nitroreductase BZ172_20580 ENOG4108RMJ sensory transduction regulator BZ172_20590 ENOG4107RUE extracellular solute-binding protein family 1 BZ172_20595 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BZ172_20600 ENOG4105F38 ABC transporter, permease BZ172_20605 ENOG4105D38 putrescine abc transporter BZ172_20610 ENOG4105RBQ inner membrane protein ybjO BZ172_20625 ENOG4106TNF Periplasmic binding protein BZ172_20630 ENOG4105DMR ABC, transporter BZ172_20635 ENOG4105GBT ABC transporter BZ172_20640 ENOG4106PMH Extracellular solute-binding protein family 3 BZ172_20645 ENOG4105E5Z arginine transporter ATP-binding subunit BZ172_20650 ENOG41064MM (LipO)protein BZ172_20675 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BZ172_20680 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BZ172_20685 ENOG4105CGD Nad-dependent epimerase dehydratase BZ172_20690 ENOG4105C5W Aldolase BZ172_20695 ENOG4105C7K acetolactate synthase BZ172_20700 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BZ172_20710 ENOG4105DWU Membrane BZ172_20720 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BZ172_20745 ENOG4105CPB ATP-dependent endonuclease of the OLD family BZ172_20750 ENOG4108MJ5 VirK protein BZ172_20755 ENOG4105DJY efflux transporter, rnd family, mfp subunit BZ172_20765 ENOG4105VEQ Cold shock protein BZ172_20880 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ172_20895 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) BZ172_20910 ENOG4108JJ8 (ABC) transporter BZ172_20915 ENOG4108JJ9 ABC, transporter BZ172_20920 ENOG4105C3M thioredoxin reductase BZ172_20930 ENOG4105EW9 transcriptional regulator AsnC family BZ172_20935 ENOG4105CNU cell division protein FtsK BZ172_20945 ENOG4105D1H recombination factor protein RarA BZ172_20955 ENOG4107QY8 reductase BZ172_20960 ENOG4105QAX Iron-sulfur BZ172_20965 ENOG4107KGK dmso reductase anchor subunit BZ172_20970 ENOG4105CHJ isochorismatase hydrolase BZ172_20985 ENOG410642W LysR family Transcriptional regulator BZ172_21005 ENOG410642W LysR family Transcriptional regulator BZ172_21010 ENOG4108X0B nad(p)h dehydrogenase (quinone) BZ172_21015 ENOG4105F1A Pyruvate formate-lyase BZ172_21025 ENOG4105DDY UPF0142 protein ycaO BZ172_21030 ENOG4107VMU Membrane BZ172_21045 ENOG4105VNT transposase (IS4 family) protein BZ172_21050 ENOG4108K0D peptidase, M48 BZ172_21060 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) BZ172_21070 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 BZ172_21085 ENOG4105T0Z Conserved Protein BZ172_21100 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups BZ172_21105 ENOG4107S90 membrAne BZ172_21110 ENOG4106371 Methyltransferase BZ172_21120 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) BZ172_21130 ENOG4105VNT transposase (IS4 family) protein BZ172_21135 ENOG4105DIT ErfK YbiS YcfS YnhG family protein BZ172_21145 ENOG4105EAQ (twin-arginine translocation) pathway signal BZ172_21150 ENOG4105C5X domain protein BZ172_21155 ENOG4105CGF Aromatic amino acid aminotransferase BZ172_21165 ENOG4105FCK Membrane BZ172_21180 ENOG4105CD8 aminopeptidase N BZ172_21195 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BZ172_21210 ENOG4105GVF (ABC) transporter BZ172_21215 ENOG4108UZX fmn reductase BZ172_21240 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon BZ172_21245 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae BZ172_21255 ENOG4105CW0 outer membrane usher protein BZ172_21265 ENOG4108MDY Fimbrial BZ172_21270 ENOG4105Q7J Fimbrial BZ172_21275 ENOG4105MX3 Fimbrial BZ172_21280 ENOG4106PH7 chaperone BZ172_21290 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) BZ172_21295 ENOG4105QVC MOSC domain-containing protein BZ172_21305 ENOG4105C5H ABC transporter BZ172_21310 ENOG4105F1S paraquat-inducible protein a BZ172_21315 ENOG4105DY2 Paraquat-inducible protein b BZ172_21320 ENOG4108Q2G (LipO)protein BZ172_21325 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) BZ172_21335 ENOG4105DAN ATP-dependent protease BZ172_21345 ENOG4105UYK outer membrane protein a BZ172_21360 ENOG4108RZ1 DNA transformation protein BZ172_21365 ENOG4105EM2 membrane BZ172_21370 ENOG410901E Membrane BZ172_21375 ENOG41088T4 Helicase IV BZ172_21410 ENOG4105K4P CoA-binding domain protein BZ172_21425 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 BZ172_21430 ENOG4108Z0T Part of a sulfur-relay system (By similarity) BZ172_21435 ENOG4108MN8 Membrane BZ172_21460 ENOG4105E3S small subunit BZ172_21465 ENOG4105DPX Hydrogenase, large subunit BZ172_21475 ENOG4108USZ hydrogenase BZ172_21480 ENOG4108VXY Hydrogenase-1 operon protein HyaE BZ172_21485 ENOG4105MVP hydrogenase-1 operon protein HyaF BZ172_21490 ENOG4105C4M (Ubiquinol oxidase) subunit I BZ172_21495 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BZ172_21505 ENOG4105D6F Phosphatase BZ172_21510 ENOG4105D75 Capsular exopolysaccharide family BZ172_21515 ENOG4107ZF2 Phosphatase BZ172_21520 ENOG4105DAY polysaccharide export protein BZ172_21525 ENOG4105E3R (LipO)protein BZ172_21530 ENOG4108W78 Pfam:DUF1017 BZ172_21535 ENOG4108Y9B (LipO)protein BZ172_21545 ENOG41060EU Cold shock-like protein BZ172_21565 ENOG4105VEQ Cold shock protein BZ172_21580 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation BZ172_21590 ENOG4105BZU Histidine kinase BZ172_21595 ENOG4108SV3 Tmao reductase system periplasmic protein tort BZ172_21600 ENOG4106WF9 DNA-binding transcriptional regulator TorR BZ172_21605 ENOG4105CUW cytochrome C-TYPE protein BZ172_21610 ENOG4107QY8 reductase BZ172_21615 ENOG4108J2R molybdopterin oxidoreductase BZ172_21640 ENOG4105D6F Phosphatase BZ172_21645 ENOG4105XH3 BZ172_21665 ENOG4108ZQS transposase BZ172_21675 ENOG4108MVM Transposase BZ172_21680 ENOG4107TII Recombinase BZ172_21685 ENOG4105F5W AtP-binding protein BZ172_21690 ENOG4105D70 Integrase catalytic subunit BZ172_21760 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 BZ172_21770 ENOG4105C2W permease BZ172_21850 ENOG4108R86 Transcriptional regulator BZ172_21855 ENOG4105C26 Dehydrogenase BZ172_21865 ENOG4105CK7 Sodium proline symporter BZ172_21880 ENOG4105EKT )-iron permease BZ172_21885 ENOG410650H (LipO)protein BZ172_21900 ENOG4105D5M phosphate starvation-inducible protein BZ172_21935 ENOG4107XHZ cytoplasmic chaperone TorD family protein BZ172_21940 ENOG4108UQ5 membrane protein YcdZ BZ172_21945 ENOG4105P8Q Curli production assembly transport component CsgG BZ172_21950 ENOG4108WYR Curli production assembly transport component, CsgF BZ172_21955 ENOG4108XDW curli assembly protein CsgE BZ172_21960 ENOG41086KC Transcriptional regulator BZ172_21980 ENOG41086KC Transcriptional regulator BZ172_22005 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers BZ172_22010 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin BZ172_22035 ENOG4108UVJ appr-1-p processing domain protein BZ172_22040 ENOG4107RZC phospholipase d BZ172_22055 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) BZ172_22060 ENOG4105VNT transposase (IS4 family) protein BZ172_22065 ENOG4105NAC (LipO)protein BZ172_22070 ENOG4108W47 Acidic protein msyB BZ172_22090 ENOG410836F Transposase BZ172_22095 ENOG4105F5W AtP-binding protein BZ172_22100 ENOG4105D70 Integrase catalytic subunit BZ172_22105 ENOG4108MVM Transposase BZ172_22115 ENOG4108ZQS transposase BZ172_22140 ENOG4105D1S lipid A biosynthesis BZ172_22150 ENOG4108YYC ycei family BZ172_22155 ENOG4105DS1 cytochrome b561 BZ172_22180 ENOG4105PVA Biofilm formation regulatory protein BssS BZ172_22185 ENOG4105MEA DNA damage-inducible protein i BZ172_22195 ENOG4105F3T (LipO)protein BZ172_22200 ENOG4105E9S glutaredoxin 2 BZ172_22210 ENOG4105D9U N-acetyltransferase BZ172_22220 ENOG4105EP9 oxidoreductase BZ172_22225 ENOG4105CJR Integral membrane protein (MviN BZ172_22230 ENOG4105QVD Flagella synthesis protein FlgN BZ172_22235 ENOG4105M9M anti-sigma28 factor FlgM BZ172_22240 ENOG4105CKS Flagella basal body P-ring formation protein flgA BZ172_22245 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BZ172_22250 ENOG4108ZC9 flagellar basal-body rod protein flgc BZ172_22255 ENOG4105W00 Flagellar hook capping protein BZ172_22260 ENOG4105BZE flagellar hook protein, FlgE BZ172_22265 ENOG4108KPB Flagellar basal-body rod protein FlgF BZ172_22285 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BZ172_22290 ENOG4105E1Q flagellar hook-associated protein BZ172_22295 ENOG4105DTJ flagellar hook-associated protein BZ172_22300 ENOG4107QQB Ribonuclease E BZ172_22305 ENOG41071G1 Uncharacterized protein YceQ BZ172_22310 ENOG4105EI2 Pseudouridine synthase BZ172_22315 ENOG4108UHJ MAF-like protein BZ172_22320 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein BZ172_22340 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BZ172_22345 ENOG4105CHR reductase BZ172_22350 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) BZ172_22355 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ172_22360 ENOG4105YAZ 4-amino-4-deoxychorismate lyase BZ172_22365 ENOG4105HHA aminodeoxychorismate lyase BZ172_22375 ENOG4107QRG dna polymerase iii BZ172_22380 ENOG4105F8V Hydrolase, tatD family BZ172_22385 ENOG4105CI1 PTS System BZ172_22395 ENOG4105K59 histidine triad (HIT) protein BZ172_22400 ENOG41090DQ Lipoprotein BZ172_22405 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) BZ172_22425 ENOG4105CEP NADH dehydrogenase BZ172_22435 ENOG4107MBR 17 kDa surface antigen BZ172_22440 ENOG4108IND Tetr family transcriptional regulator BZ172_22445 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction BZ172_22455 ENOG4108JA2 transcriptioN-repair coupling factor BZ172_22460 ENOG4105IQC Inner membrane protein YcfT BZ172_22465 ENOG4105D60 lipoprotein releasing system transmembrane protein BZ172_22470 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BZ172_22475 ENOG4105D60 lipoprotein releasing system transmembrane protein BZ172_22485 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BZ172_22490 ENOG4107RUE extracellular solute-binding protein family 1 BZ172_22495 ENOG4105D38 putrescine abc transporter BZ172_22500 ENOG4105F38 ABC transporter, permease BZ172_22520 ENOG4105EZE Cupin 4 family protein BZ172_22525 ENOG4105IFJ Histidine kinase BZ172_22530 ENOG4105XJC Two component transcriptional regulator (Winged helix family BZ172_22535 ENOG4107QTF adenylosuccinate lyase BZ172_22555 ENOG4108R99 pseudouridine synthase BZ172_22560 ENOG4108HMX isocitrate dehydrogenase (NADP) BZ172_22575 ENOG41064WM Uncharacterized protein YcgX BZ172_22580 ENOG4108XDN Transcriptional regulator BZ172_22615 ENOG4108ZQS transposase BZ172_22620 ENOG4108MVM Transposase BZ172_22625 ENOG410658X BZ172_22660 ENOG4107QMS site-determining protein BZ172_22675 ENOG4105S66 prophage protein BZ172_22680 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium BZ172_22690 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase BZ172_22700 ENOG4106PXS Toxin, which has some hemolytic activity towards mammalian cells. Acts by forming a pore-like structure upon contact with mammalian cells BZ172_22735 ENOG4105KT5 UmuD protein BZ172_22740 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BZ172_22755 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BZ172_22775 ENOG4105ED1 spovr family BZ172_22785 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BZ172_22795 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BZ172_22810 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) BZ172_22860 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ172_22865 ENOG4108M9K flagella biosynthesis protein FliZ BZ172_22885 ENOG4108M9K flagella biosynthesis protein FliZ BZ172_22890 ENOG4105EAB amino acid AbC transporter BZ172_22905 ENOG4105E5Q amino acid AbC transporter BZ172_22910 ENOG4105CDA abc transporter atp-binding protein BZ172_22915 ENOG4105VJY transcriptional regulator BZ172_22920 ENOG4105XVG cytoplasmic protein BZ172_22930 ENOG4105WH1 Two component transcriptional regulator luxr family BZ172_22940 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BZ172_22960 ENOG4106RHG Yeca family BZ172_22965 ENOG4105E0U tyrosine-specific transport protein BZ172_22970 ENOG4105VVZ metal-binding protein BZ172_22975 ENOG41090A1 ferritin BZ172_22980 ENOG4105P23 (LipO)protein BZ172_22990 ENOG4105N4N Protein of unknown function (DUF2766) BZ172_22995 ENOG4108UEC Ferritin-like protein BZ172_23005 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator BZ172_23015 ENOG4105CNN ABC, transporter BZ172_23020 ENOG4108K4C ec 3.1.3.12 BZ172_23030 ENOG4108VA4 Universal stress protein BZ172_23050 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region BZ172_23055 ENOG4107RD7 Flagellar Motor Protein, MotA BZ172_23060 ENOG4105ER2 Ompa motb domain protein BZ172_23065 ENOG4105CBS Chea signal transduction histidine kinase BZ172_23070 ENOG4108V3W Chemotaxis protein, CheW BZ172_23080 ENOG4105C8Q Methyl-accepting chemotaxis BZ172_23085 ENOG4105BZU Histidine kinase BZ172_23090 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) BZ172_23095 ENOG4108VYJ response regulator receiver protein BZ172_23135 ENOG4105D00 flagellar biosynthetic protein flhB BZ172_23160 ENOG4106ZCM YecM protein BZ172_23170 ENOG4105CUW cytochrome C-TYPE protein BZ172_23175 ENOG4108J2R molybdopterin oxidoreductase BZ172_23185 ENOG4107QY8 reductase BZ172_23200 ENOG4105WJG Glutathione BZ172_23205 ENOG41081XQ Conserved Protein BZ172_23210 ENOG4108C33 Resolvase BZ172_23290 ENOG4105HGD Antitermination protein BZ172_23295 ENOG4105KSK (crossover) junction endodeoxyribonuclease BZ172_23320 ENOG4108ZQS transposase BZ172_23330 ENOG4108MVM Transposase BZ172_23385 ENOG4106FE3 DNA repair BZ172_23395 ENOG4105D3W isochorismatase BZ172_23405 ENOG4108TIT dATP pyrophosphohydrolase BZ172_23410 ENOG4105CDY transcriptional regulatory protein BZ172_23420 ENOG4107S01 Repressor protein MetJ BZ172_23440 ENOG4105FAV ABC, transporter BZ172_23445 ENOG4105FDK ABC transporter BZ172_23450 ENOG4105NXV High-affinity zinc uptake system protein BZ172_23455 ENOG4105DR5 peptidase BZ172_23460 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase BZ172_23515 ENOG4105CA9 Pyruvate kinase BZ172_23520 ENOG4106KNT transcriptional regulator BZ172_23535 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BZ172_23540 ENOG4105C01 Dihydroxy-acid dehydratase BZ172_23545 ENOG4108UHU Aldolase BZ172_23555 ENOG4105X2V dna damage-inducible protein BZ172_23560 ENOG4105RSZ secreted protein BZ172_23575 ENOG4108Q2J Inner membrane protein YebE BZ172_23585 ENOG4105CUG Oligopeptidase b BZ172_23590 ENOG4105UMD exodeoxyribonuclease X BZ172_23595 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BZ172_23600 ENOG4105MPK DNA polymerase III subunit theta BZ172_23605 ENOG4105FXM Copper resistance protein BZ172_23610 ENOG4108PNC copper resistance BZ172_23615 ENOG4105NKT exported protein BZ172_23625 ENOG4108I1J Integrase BZ172_23635 ENOG4108MVM Transposase BZ172_23640 ENOG4108ZQS transposase BZ172_23655 ENOG4105QYW Excisionase-like protein from lambdoid prophage 14 BZ172_23670 ENOG4108QHK Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway BZ172_23685 ENOG4108R1E Serine threonine protein phosphatase 1 BZ172_23715 ENOG4105UVW uncharacterized protein yebW BZ172_23740 ENOG4105DY2 Paraquat-inducible protein b BZ172_23745 ENOG4105H2K paraquat-inducible protein a BZ172_23750 ENOG4108ZGC gaf domain protein BZ172_23760 ENOG4105CN1 protease BZ172_23775 ENOG4105J4Q Transcriptional regulator BZ172_23780 ENOG4105TIK BZ172_23790 ENOG4105Q3Y exported protein BZ172_23800 ENOG410610J Protein of unknown function (DUF2627) BZ172_23805 ENOG4105VEQ Cold shock protein BZ172_23810 ENOG4105DHI Methyltransferase BZ172_23830 ENOG4105F3R pts system mannose fructose sorbose family iid BZ172_23835 ENOG4105ETZ PTS System BZ172_23840 ENOG4108EQA pts system BZ172_23855 ENOG4105EE5 Membrane protein terC BZ172_23860 ENOG4107XTP (EAL) domain protein BZ172_23865 ENOG4105EJQ L-serine dehydratase BZ172_23875 ENOG4105CRQ synthase (Component I) BZ172_23885 ENOG4105V2F Uncharacterized protein yoac BZ172_23910 ENOG4105M4H endoribonuclease L-psp BZ172_23915 ENOG4105DVT helicase BZ172_23920 ENOG41072GX Peptidase M22 Glycoprotease BZ172_23925 ENOG4105Y4Z Outer Membrane Lipoprotein BZ172_23930 ENOG4105CEY Amp-dependent synthetase and ligase BZ172_23935 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) BZ172_23940 ENOG4105E3J oxidoreductase BZ172_23945 ENOG4105DVW rieske (2Fe-2S) BZ172_23950 ENOG4105C94 Transporter BZ172_23955 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BZ172_23960 ENOG4105EJC lysr family transcriptional regulator BZ172_23970 ENOG4108YS1 cytoplasmic protein BZ172_23975 ENOG4105YP6 Domain of unknown function (DUF1869) BZ172_23980 ENOG4105Y3U Transglycosylase-associated protein BZ172_23990 ENOG4106G4W BZ172_23995 ENOG410620I Diguanylate cyclase BZ172_24000 ENOG4105UCG Domain of unknown function (DUF333) BZ172_24005 ENOG4105K78 MarR family Transcriptional regulator BZ172_24010 ENOG4105DJ2 Major Facilitator Superfamily BZ172_24015 ENOG4105R1U AraC Family Transcriptional Regulator BZ172_24030 ENOG4108KXH Ybak prolyl-tRNA synthetase associated BZ172_24035 ENOG4108KHP Diguanylate cyclase BZ172_24055 ENOG4106KTS Inner membrane protein yeaI BZ172_24065 ENOG4105CYN Serine protein kinase BZ172_24070 ENOG4105GNX MltA-interacting MipA family protein BZ172_24075 ENOG4105CV8 reductase BZ172_24080 ENOG4105DSB aldose 1-epimerase BZ172_24085 ENOG4105VNT transposase (IS4 family) protein BZ172_24090 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BZ172_24100 ENOG4105VUT cytoplasmic protein BZ172_24105 ENOG4108RWI nicotinamidase BZ172_24110 ENOG4105HDK L-asparaginase BZ172_24115 ENOG4105D07 Signal peptide peptidase, SppA BZ172_24120 ENOG41069NU Nitroreductase BZ172_24135 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BZ172_24160 ENOG41065FB inner membrane protein ynji BZ172_24165 ENOG41065FB inner membrane protein ynji BZ172_24170 ENOG4105D82 Glutamate dehydrogenase BZ172_24175 ENOG4105MTM Protein of unknown function (DUF1496) BZ172_24180 ENOG4105M6F mutator MutT protein BZ172_24185 ENOG4108T9J Cdp-alcohol phosphatidyltransferase BZ172_24205 ENOG4108T9J Cdp-alcohol phosphatidyltransferase BZ172_24210 ENOG4107RM6 sulfurtransferase BZ172_24215 ENOG4108VGW abc transporter atp-binding protein BZ172_24225 ENOG4105VNH ABC transporter solute-binding protein BZ172_24230 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) BZ172_24235 ENOG4108N5C SNARE associated Golgi protein-related protein BZ172_24240 ENOG4108KCW iron-sulfur cluster binding BZ172_24245 ENOG4108RSN SNARE associated Golgi BZ172_24250 ENOG4105CGK Exodeoxyribonuclease III BZ172_24290 ENOG4108SPG Periplasmic Protein BZ172_24310 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) BZ172_24325 ENOG4105KKI DNA-binding transcriptional activator OsmE BZ172_24335 ENOG4105VZJ PTS System BZ172_24340 ENOG4105CK1 PTS System BZ172_24345 ENOG4105VCP PTS System BZ172_24350 ENOG4105EZV Transcriptional regulator BZ172_24355 ENOG4105F8D glycoside hydrolase family 4 BZ172_24370 ENOG4105CH6 catalase BZ172_24390 ENOG4108ETY sodium dicarboxylate symporter BZ172_24395 ENOG4107K5X Membrane-bound metal-dependent hydrolase BZ172_24400 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 BZ172_24405 ENOG4107PN8 YfeABCD locus regulator BZ172_24410 ENOG4105FGM Fructosamine kinase BZ172_24415 ENOG4105P10 Uncharacterized protein ydiZ BZ172_24420 ENOG4105DE4 1-phosphofructokinase BZ172_24425 ENOG4108NE3 Salt-induced outer membrane protein BZ172_24475 ENOG41082NX 50s ribosomal protein l35 BZ172_24480 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) BZ172_24510 ENOG4108V06 Glutathione peroxidase BZ172_24520 ENOG4108QBX (LipO)protein BZ172_24530 ENOG4108TC0 Diguanylate phosphodiesterase BZ172_24540 ENOG4106EDX Hemin uptake protein BZ172_24545 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BZ172_24555 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BZ172_24580 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) BZ172_24595 ENOG4105EMV Major Facilitator BZ172_24620 ENOG4105EMV Major Facilitator BZ172_24625 ENOG4105SUA Ydil protein BZ172_24650 ENOG4105IPI Membrane BZ172_24660 ENOG4105CQB FAD linked oxidase domain protein BZ172_24665 ENOG4105KA0 thioesterase Superfamily protein BZ172_24670 ENOG410671Z uncharacterized protein ydiH BZ172_24675 ENOG4108Z4V iron-sulfur cluster assembly BZ172_24680 ENOG4105DIW FeS assembly protein SUFB BZ172_24685 ENOG4105C3K feS assembly ATPase SufC BZ172_24690 ENOG4105JRK feS assembly protein SufD BZ172_24705 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BZ172_24710 ENOG4105KMX major outer membrane lipoprotein BZ172_24715 ENOG4105CA9 Pyruvate kinase BZ172_24720 ENOG4105RFR Protein of unknown function (DUF2767) BZ172_24725 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein BZ172_24730 ENOG4105WE2 aldehyde ferredoxin oxidoreductase BZ172_24735 ENOG4105JVW BZ172_24740 ENOG4108393 oxidoreductase Fe-S subunit BZ172_24745 ENOG4108NWD Cytochrome BZ172_24750 ENOG4108Y7C Conserved Protein BZ172_24755 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain BZ172_24760 ENOG4105N0V mono-oxygenase ydhR BZ172_24785 ENOG4108R6K riboflavin synthase, subunit alpha BZ172_24790 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BZ172_24795 ENOG4105CZQ inner membrane transport protein YdhC BZ172_24800 ENOG4105F52 Transcriptional regulator BZ172_24820 ENOG4105F27 Major Facilitator BZ172_24825 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BZ172_24830 ENOG4105K4H Nlp p60 protein BZ172_24835 ENOG4105M2J Glutaredoxin BZ172_24850 ENOG4108UYE Lactoylglutathione lyase BZ172_24855 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BZ172_24860 ENOG4108WUH Transcriptional regulator, TetR family BZ172_24865 ENOG4105XZD Fe-S protein BZ172_24870 ENOG4107RGM aldo keto reductase BZ172_24875 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BZ172_24880 ENOG4105DSW Fusaric acid resistance protein BZ172_24885 ENOG4105Y49 secretion protein, HlyD family BZ172_24900 ENOG4108XTF Outer Membrane Lipoprotein BZ172_24910 ENOG410642K Lysozyme inhibitor BZ172_24930 ENOG4108K3A Glutathione S-transferase BZ172_24935 ENOG4105VNT transposase (IS4 family) protein BZ172_24940 ENOG4108K3A Glutathione S-transferase BZ172_24945 ENOG4105DUX Transporter BZ172_24955 ENOG4105CSM endonuclease III BZ172_24965 ENOG4108UQQ Electron transport complex BZ172_24990 ENOG4105M9B inner membrane protein ydgK BZ172_24995 ENOG4105QZ5 OriC-binding nucleoid-associated protein BZ172_25005 ENOG4106C6R beta-lactam resistance protein BZ172_25010 ENOG4105D9R oxidoreductase BZ172_25020 ENOG4105C87 Aminotransferase class I and II BZ172_25025 ENOG4105CI1 PTS System BZ172_25030 ENOG4107P2S Transcriptional regulator BZ172_25040 ENOG4107ZQV short-chain dehydrogenase reductase BZ172_25045 ENOG4105XEA Tetr family transcriptional regulator BZ172_25050 ENOG4105CNT hydrolase family 2 BZ172_25055 ENOG4105CT4 transporter BZ172_25060 ENOG4108QNI outer membrane porin protein BZ172_25065 ENOG4106J39 exported protein BZ172_25070 ENOG4105EIP mannose-6-phosphate isomerase BZ172_25075 ENOG4107GFK fumarate BZ172_25080 ENOG4105C9Q fumarate hydratase class II BZ172_25090 ENOG4105JJR Histidine kinase BZ172_25095 ENOG4107EXC regulatoR BZ172_25100 ENOG4105RA2 Membrane BZ172_25110 ENOG4105D5Q Arginine ornithine antiporter BZ172_25120 ENOG4105C5D exported protein BZ172_25125 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BZ172_25130 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BZ172_25135 ENOG4105DSF transport protein BZ172_25150 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap BZ172_25165 ENOG4108MVM Transposase BZ172_25185 ENOG4108ZQS transposase BZ172_25200 ENOG4105D94 Major Facilitator Superfamily BZ172_25205 ENOG4106NZI LysR family Transcriptional regulator BZ172_25210 ENOG4105DAG ROK family BZ172_25215 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BZ172_25220 ENOG4105CMQ Chloride channel BZ172_25225 ENOG4108NEM leader-binding protein dmsD BZ172_25230 ENOG4107KGK dmso reductase anchor subunit BZ172_25235 ENOG4105QAX Iron-sulfur BZ172_25240 ENOG4108KU3 Integrase BZ172_25270 ENOG41076J9 exonuclease VIII BZ172_25330 ENOG4105JBR DNA replication protein BZ172_25360 ENOG4105MRD Phage derived protein Gp49-like (DUF891) BZ172_25385 ENOG4105NY2 NinB protein BZ172_25395 ENOG4105RWQ Protein of unknown function (DUF1364) BZ172_25410 ENOG4105HRS Antitermination protein BZ172_25450 ENOG4105QFS Lysis protein S homolog from lambdoid prophage BZ172_25470 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 BZ172_25475 ENOG4105QYK bacteriophage lambda Bor protein homolog BZ172_25560 ENOG4108T1M outer membrane protein x BZ172_25635 ENOG4105XB7 anti-repressor protein BZ172_25640 ENOG4105XB7 anti-repressor protein BZ172_25650 ENOG4105QAX Iron-sulfur BZ172_25710 ENOG4105JBR DNA replication protein BZ172_25755 ENOG4105DEI Mannitol dehydrogenase BZ172_25760 ENOG41061EV selenium-binding protein YdfZ BZ172_25765 ENOG4107XBN GntR Family Transcriptional Regulator BZ172_25770 ENOG4105EMU Dehydrogenase BZ172_25780 ENOG4105DGW oligopeptidase A BZ172_25790 ENOG4108WTK competence damage-inducible protein BZ172_25795 ENOG4108YDI single-species biofilm formation on inanimate substrate BZ172_25800 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria BZ172_25820 ENOG4105CS2 ec 3.2.1.21 BZ172_25825 ENOG4106DNR multiple antibiotic resistance protein BZ172_25830 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF BZ172_25835 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes BZ172_25855 ENOG4105EGI Transcriptional regulator BZ172_25860 ENOG4105C26 Dehydrogenase BZ172_25865 ENOG4105CSV Glutaminase BZ172_25870 ENOG4105M0C cytoplasmic protein BZ172_25890 ENOG4105BZU Histidine kinase BZ172_25955 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein BZ172_25970 ENOG4108MVM Transposase BZ172_26005 ENOG4108MVM Transposase BZ172_26010 ENOG4106318 fimbrial-like protein YdeR BZ172_26015 ENOG4106PIH fimbrial-like protein ydeQ BZ172_26020 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit BZ172_26030 ENOG4105Z68 AraC Family Transcriptional Regulator BZ172_26035 ENOG4105ENH Sulfatase BZ172_26040 ENOG4105C4X radical SAM domain protein BZ172_26045 ENOG4105CQ0 ABC transporter BZ172_26050 ENOG4105VNT transposase (IS4 family) protein BZ172_26055 ENOG4105PE1 Receptor BZ172_26060 ENOG4107RAN Peptidase, M16 BZ172_26075 ENOG4105CVK Glutamate decarboxylase BZ172_26080 ENOG4105E5D amino acid BZ172_26085 ENOG4105F32 YngK protein BZ172_26095 ENOG4105BZU Histidine kinase BZ172_26100 ENOG4108UQS dipeptidase BZ172_26105 ENOG4105DEF Extracellular solute-binding protein, family 5 BZ172_26110 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BZ172_26115 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ172_26120 ENOG4105C3U ABC transporter BZ172_26125 ENOG4107H6U ABC transporter BZ172_26130 ENOG4108Z9K Osmotically inducible protein BZ172_26155 ENOG4105TPS biofilm-dependent modulation protein BZ172_26160 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein BZ172_26175 ENOG41084S7 Plasmid maintenance system antidote protein BZ172_26180 ENOG4108MG3 formate dehydrogenase BZ172_26185 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein BZ172_26195 ENOG4105RPH Inner membrane protein YddG BZ172_26225 ENOG4108MVM Transposase BZ172_26235 ENOG4108ZQS transposase BZ172_26240 ENOG4107QND Nitrite extrusion protein BZ172_26245 ENOG4105CRU nitrate reductase, alpha subunit BZ172_26250 ENOG4108IUE nitrate reductase beta subunit BZ172_26255 ENOG4108NZN Respiratory nitrate reductase 2 delta chain BZ172_26260 ENOG4105D0D Nitrate reductase 2, gamma subunit BZ172_26265 ENOG4105JAB phenazine biosynthesis protein, phzf family BZ172_26270 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BZ172_26275 ENOG4108MEJ flavin reductase domain protein BZ172_26290 ENOG410600T transposase BZ172_26315 ENOG4105F5W AtP-binding protein BZ172_26320 ENOG4105D70 Integrase catalytic subunit BZ172_26340 ENOG410600T transposase BZ172_26345 ENOG4105CNA YD repeat protein BZ172_26355 ENOG4105CS6 Rhs element vgr protein BZ172_26365 ENOG4108N27 Glutathione S-transferase BZ172_26370 ENOG4105C85 amino acid BZ172_26375 ENOG4108NS2 receptor BZ172_26390 ENOG4105CHB tonB-dependent Receptor BZ172_26395 ENOG4108WYP Transcriptional regulator BZ172_26410 ENOG4108WYP Transcriptional regulator BZ172_26430 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein BZ172_26440 ENOG4108Z7F N-acetyltransferase BZ172_26445 ENOG4108T9Y Inner membrane protein ydcZ BZ172_26450 ENOG4105R71 cytoplasmic protein BZ172_26455 ENOG410654E Membrane BZ172_26490 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component BZ172_26500 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BZ172_26505 ENOG4107TYH extracellular solute-binding protein family 1 BZ172_26510 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BZ172_26515 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin BZ172_26535 ENOG4105RR0 Protein of unknown function (DUF2554) BZ172_26540 ENOG4105CFP Peptidase U32 BZ172_26545 ENOG4108JCI Transcriptional regulator BZ172_26550 ENOG4105DKK Benzoate BZ172_26580 ENOG4105DKK Benzoate BZ172_26585 ENOG4105D7V transposase BZ172_26620 ENOG41088CC tellurite resistance protein tehB BZ172_26625 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein BZ172_26630 ENOG4107WE3 acetyltransferase YdcK BZ172_26635 ENOG4108Z9I -acetyltransferase BZ172_26640 ENOG4105Z2P Protein of unknown function (DUF465) BZ172_26660 ENOG4105E32 cytoplasmic protein BZ172_26665 ENOG4105DDW LysR family Transcriptional regulator BZ172_26670 ENOG4105C8Q Methyl-accepting chemotaxis BZ172_26675 ENOG4107NK6 Hok/gef family BZ172_26680 ENOG4105UPP uncharacterized protein ydcA BZ172_26685 ENOG4105CPW cytochrome b561 BZ172_26690 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BZ172_26695 ENOG4105C26 Dehydrogenase BZ172_26700 ENOG4105C26 Dehydrogenase BZ172_26735 ENOG4107DB1 DUF218 domain BZ172_26740 ENOG4105CQ7 ATP-dependent helicase BZ172_26750 ENOG41077RS Phosphatase BZ172_26755 ENOG4105E8V Alpha Beta Hydrolase Fold protein BZ172_26760 ENOG4108HPI phosphatidate Cytidylyltransferase BZ172_26775 ENOG4108WFR AraC Family Transcriptional Regulator BZ172_26785 ENOG4108ZQS transposase BZ172_26790 ENOG4108MVM Transposase BZ172_26795 ENOG4108WFR AraC Family Transcriptional Regulator BZ172_26800 ENOG4105WXT Conserved Protein BZ172_26805 ENOG410689M (LipO)protein BZ172_26810 ENOG4107H52 Dicarboxylate transport BZ172_26815 ENOG4105C5I Dehydrogenase BZ172_26820 ENOG41090X5 Heat shock protein hslJ BZ172_26830 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) BZ172_26840 ENOG4105FCK Membrane BZ172_26845 ENOG4108RW8 Universal stress protein F BZ172_26855 ENOG4105DIK (ABC) transporter BZ172_26860 ENOG4105CC5 ABC transporter BZ172_26865 ENOG4105CC5 ABC transporter BZ172_27065 ENOG4105RWQ Protein of unknown function (DUF1364) BZ172_27090 ENOG4105WI6 cell killing protein encoded within cryptic prophage BZ172_27150 ENOG4107R08 Integrase BZ172_27155 ENOG4105CB3 Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity) BZ172_27160 ENOG4105C1J atp-dependent rna helicase BZ172_27175 ENOG4105BZU Histidine kinase BZ172_27180 ENOG4108DG9 Smr protein MutS2 BZ172_27190 ENOG4106KR7 LysR family Transcriptional regulator BZ172_27195 ENOG4105CH2 amidohydrolase BZ172_27200 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B BZ172_27210 ENOG4105CFC Transporter BZ172_27225 ENOG4105CFC Transporter BZ172_27230 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BZ172_27235 ENOG4105DS0 Transcriptional regulator, Crp Fnr family BZ172_27240 ENOG4105Q9Y Universal stress protein BZ172_27245 ENOG4105S5I Membrane BZ172_27270 ENOG4105D64 Mechanosensitive ion channel BZ172_27275 ENOG4107QSI ABC, transporter BZ172_27280 ENOG4105WPN DNA integration recombination invertion protein BZ172_27285 ENOG4105EQ2 LysR family Transcriptional regulator BZ172_27290 ENOG4105ENX hydrolase BZ172_27295 ENOG4105ENX hydrolase BZ172_27335 ENOG4105KXI murein peptide amidase A BZ172_27340 ENOG4107S8C mandelate racemase muconate lactonizing BZ172_27345 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BZ172_27350 ENOG4108JU8 Transcriptional regulator BZ172_27375 ENOG4105CM6 amino acid regulated cytosolic protein BZ172_27380 ENOG4105FKQ transcriptional regulator BZ172_27385 ENOG4107EFV Outer membrane protein G BZ172_27400 ENOG4108IJ9 (ABC) transporter BZ172_27405 ENOG4107URF beta-phospho-glucomutase BZ172_27410 ENOG4105C71 hydrolase family 65, central catalytic BZ172_27415 ENOG4105CK5 oxidoreductase BZ172_27420 ENOG4107TYA transient receptor potential locus BZ172_27425 ENOG4107RRD Dehydrogenase BZ172_27435 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component BZ172_27440 ENOG4105WEM extracellular solute-binding protein BZ172_27450 ENOG4105K8Z Phage shock protein BZ172_27455 ENOG4105NNG Peripheral inner membrane phage-shock protein BZ172_27460 ENOG4105FM1 phage shock protein C BZ172_27465 ENOG4105YYT phage shock protein B BZ172_27470 ENOG41087YS Phage shock protein A BZ172_27475 ENOG4105E51 psp operon transcriptional activator BZ172_27485 ENOG4105CJP fad dependent oxidoreductase BZ172_27490 ENOG4105C26 Dehydrogenase BZ172_27495 ENOG4105C26 Dehydrogenase BZ172_27500 ENOG4107VRI Transcriptional regulator BZ172_27505 ENOG4108Z86 Glutamine amidotransferase BZ172_27510 ENOG4105CFQ glutamine synthetase BZ172_27515 ENOG4105CUB amino acid BZ172_27520 ENOG4105N0E Protein of unknown function (DUF2543) BZ172_27530 ENOG4108HIY periplasmic BZ172_27535 ENOG4108I5W peptide transport system, permease protein BZ172_27540 ENOG4108EU3 peptide transport system, permease BZ172_27545 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein BZ172_27550 ENOG4108JQ2 peptide transport system atp-binding protein BZ172_27555 ENOG4105WDY DNA (cytosine-5-)-methyltransferase BZ172_27560 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH BZ172_27590 ENOG4105N2W Transcriptional regulator BZ172_27595 ENOG41061RM osmotically inducible lipoprotein BZ172_27600 ENOG4108ZJT translation initiation factor, Sui1 BZ172_27610 ENOG4105CFV Tetratricopeptide repeat protein BZ172_27615 ENOG4105Q4A inner membrane protein yciS BZ172_27620 ENOG4105EYK Phosphatidylglycerophosphatase B BZ172_27630 ENOG4107QM5 aconitate hydratase BZ172_27665 ENOG4107R11 Transcriptional regulator BZ172_27675 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BZ172_27680 ENOG4105RKX Protein of unknown function (DUF2498) BZ172_27685 ENOG4105ERU peptidase BZ172_27695 ENOG4105UBK short-chain dehydrogenase reductase BZ172_27700 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase BZ172_27705 ENOG4105FE9 pseudouridine synthase BZ172_27710 ENOG4105EG3 transmembrane signal peptide protein BZ172_27715 ENOG4105EG3 transmembrane signal peptide protein BZ172_27720 ENOG4107RTD sua5 ycio yrdc ywlc family protein BZ172_27725 ENOG4105DB7 PHP domain protein BZ172_27730 ENOG4105CRQ synthase (Component I) BZ172_27735 ENOG4108EFP Anthranilate synthase component II BZ172_27740 ENOG4105DK0 Indole-3-glycerol phosphate synthase BZ172_27745 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) BZ172_27770 ENOG4105EIF outer membrane protein W BZ172_27795 ENOG4108WF3 methyltransferase BZ172_27810 ENOG4108C33 Resolvase BZ172_27830 ENOG4105UZW Tail fiber assembly protein BZ172_27855 ENOG4105QFS Lysis protein S homolog from lambdoid prophage BZ172_27900 ENOG4105HGD Antitermination protein BZ172_27905 ENOG4105KSK (crossover) junction endodeoxyribonuclease BZ172_27910 ENOG4108MXB Protein of unknown function (DUF968) BZ172_27925 ENOG4105WI6 cell killing protein encoded within cryptic prophage BZ172_27975 ENOG4108I1J Integrase BZ172_27980 ENOG4105EIF outer membrane protein W BZ172_28000 ENOG4105NAU thioesterase Superfamily protein BZ172_28005 ENOG410822N TonB family BZ172_28020 ENOG4108ZQS transposase BZ172_28030 ENOG4108MVM Transposase BZ172_28115 ENOG4108C33 Resolvase BZ172_28120 ENOG4105K9H YciI-like protein BZ172_28135 ENOG4107SVH Potassium channel protein BZ172_28155 ENOG4108JQ7 (ABC) transporter BZ172_28160 ENOG4105C3U ABC transporter BZ172_28165 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ172_28175 ENOG4108J59 Extracellular solute-binding protein, family 5 BZ172_28185 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein BZ172_28190 ENOG4108EKI Dehydrogenase BZ172_28195 ENOG4105VNT transposase (IS4 family) protein BZ172_28205 ENOG4107104 thymidine kinase BZ172_28210 ENOG4108SAU DNA-binding protein H-ns BZ172_28215 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BZ172_28220 ENOG4105I93 response regulator BZ172_28225 ENOG4105D78 K07001 NTE family protein BZ172_28235 ENOG4105CIY formyltetrahydrofolate deformylase BZ172_28250 ENOG41076YT nitrate reductase, gamma subunit BZ172_28255 ENOG4105R3A Nitrate reductase BZ172_28260 ENOG4108IUE nitrate reductase beta subunit BZ172_28265 ENOG4105CRU nitrate reductase, alpha subunit BZ172_28270 ENOG4105DQQ Major facilitator superfamily MFS_1 BZ172_28280 ENOG4105BZU Histidine kinase BZ172_28285 ENOG4105WH1 Two component transcriptional regulator luxr family BZ172_28290 ENOG4105ID0 Putative invasin BZ172_28295 ENOG41090EX DsrE family BZ172_28300 ENOG4108NH8 Cation transport protein BZ172_28305 ENOG4105WS7 Cation transport regulator BZ172_28310 ENOG4105EWV Sodium calcium exchanger membrane region BZ172_28350 ENOG4108YY7 Invasion gene expression up-regulator SirB BZ172_28355 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BZ172_28380 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BZ172_28385 ENOG4105CHH sulfate transporter BZ172_28390 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria BZ172_28400 ENOG4105C3G gtp-binding protein BZ172_28445 ENOG4105MQ3 flagellar protein FliS BZ172_28455 ENOG4105E5K Alpha-amylase BZ172_28460 ENOG4108W9D (LipO)protein BZ172_28470 ENOG41066VF YeeE YedE family protein BZ172_28475 ENOG4105KSU Redox protein BZ172_28480 ENOG4108RAV Conserved protein BZ172_28485 ENOG4105D7V transposase BZ172_28515 ENOG4108ZQS transposase BZ172_28520 ENOG4108MVM Transposase BZ172_28525 ENOG4108UQN AraC family transcriptional regulator BZ172_28530 ENOG4108V1U phospholipid-binding protein BZ172_28535 ENOG410814C multidrug resistance protein BZ172_28550 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BZ172_28555 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BZ172_28560 ENOG41090PJ Flagellar assembly protein BZ172_28565 ENOG4108JIR Flagellum-specific ATP synthase BZ172_28570 ENOG4105GSA Flagellar export protein flij BZ172_28575 ENOG4105WF4 Flagellar hook-length control protein BZ172_28580 ENOG4107ZI8 flagellar basal body-associated protein flil BZ172_28585 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BZ172_28590 ENOG4105DD5 Flagellar motor switch protein BZ172_28595 ENOG4105K0P flagellar biosynthesis protein BZ172_28600 ENOG4105CN7 Flagellar biosynthetic protein FliP BZ172_28605 ENOG4105VS8 Flagellar biosynthetic protein fliq BZ172_28610 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BZ172_28615 ENOG4107TKS colanic acid capsular biosynthesis activation protein A BZ172_28630 ENOG4105YX3 cellular response to acidity BZ172_28650 ENOG4105VNZ cytoplasmic protein BZ172_28655 ENOG4105CKW Inner membrane protein yedI BZ172_28665 ENOG41090BB DNA mismatch endonuclease (vsr) BZ172_28670 ENOG4105DVF Cytosine-specific methyltransferase BZ172_28675 ENOG4105EST Metal Dependent Phosphohydrolase BZ172_28680 ENOG4105Y0K Inner membrane protein YedR BZ172_28705 ENOG4105FCK Membrane BZ172_28720 ENOG4108ZQS transposase BZ172_28730 ENOG4108MVM Transposase BZ172_28735 ENOG4107ZY3 Histidine kinase BZ172_28740 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BZ172_28870 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BZ172_28890 ENOG4105KK6 nuclease BZ172_28945 ENOG4107QHF type ii secretion system protein e BZ172_28975 ENOG4108EHY type IV secretion system BZ172_29000 ENOG4105EJX conjugal transfer ATPase BZ172_29100 ENOG4107QX8 SPFH domain, Band 7 family protein BZ172_29140 ENOG41074AV Hok/gef family BZ172_29220 ENOG4105CZX twitching motility protein BZ172_29465 ENOG410607W Transposase BZ172_29585 ENOG410607W Transposase BZ172_29625 ENOG410607W Transposase BZ172_29675 ENOG4105EKQ RNA-directed DNA polymerase BZ172_29730 ENOG410836F Transposase BZ172_29750 ENOG41090WB Transposase is3 is911 BZ172_29810 ENOG4105E5H Transposase BZ172_29815 ENOG4108YXQ IS66 Orf2 family protein BZ172_29915 ENOG4105SBG acid phosphatase BZ172_29940 ENOG4108MVM Transposase BZ172_29985 ENOG410607W Transposase BZ172_30030 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BZ172_30035 ENOG4107VDP teichoic acid biosynthesis BZ172_30070 ENOG4107QQG Dehydrogenase BZ172_30090 ENOG410607W Transposase BZ172_30115 ENOG410607W Transposase BZ172_30130 ENOG4108QHK Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway BZ172_30150 ENOG410607W Transposase BZ172_30170 ENOG4106CQM replication BZ172_30215 ENOG4105KF5 hemolysin expression-modulating protein BZ172_30220 ENOG4105KK6 nuclease BZ172_30230 ENOG4107CBI conjugal transfer fertility inhibition protein BZ172_30260 ENOG4105VGJ Virulence-associated protein BZ172_30265 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A BZ172_30300 ENOG4108SER Transposase BZ172_30310 ENOG4108ZQS transposase BZ172_30320 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase BZ172_30325 ENOG4108MJ5 VirK protein BZ172_30330 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) BZ172_30335 ENOG4107BJW polysaccharide deacetylase BZ172_30370 ENOG4105VNT transposase (IS4 family) protein BZ172_30490 ENOG4108ZQS transposase BZ172_30500 ENOG4108MVM Transposase BZ172_30535 ENOG4105CGH 5'-nucleotidase BZ172_30565 ENOG4106AS2 Outer membrane autotransporter BZ172_30595 ENOG4105EKQ RNA-directed DNA polymerase BZ172_30680 ENOG41090WB Transposase is3 is911 BZ172_30700 ENOG4105F5W AtP-binding protein BZ172_30705 ENOG4105D70 Integrase catalytic subunit BZ172_30730 ENOG4108M6W surface presentation of antigens protein SpaS BZ172_30740 ENOG4105U07 type iii secretion BZ172_30745 ENOG41075IY surface presentation of antigens protein SpaP BZ172_30750 ENOG4105T85 surface presentation of antigens protein BZ172_30765 ENOG4108JIR Flagellum-specific ATP synthase BZ172_30775 ENOG4108HR8 type iii secretion BZ172_30780 ENOG4105X27 type iii secretion BZ172_30790 ENOG4105YY8 Transcriptional regulator BZ172_30825 ENOG4105Y7Q type iii secretion BZ172_30830 ENOG4108RC9 Type III secretion system protein BZ172_30855 ENOG4106SB2 Plays a role in mediating bacterial evasion from the host autophagic pathway BZ172_30885 ENOG4105IBT Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of SipA, SipB, and SipC BZ172_30900 ENOG4106RMF ParB family BZ172_30930 ENOG410836F Transposase BZ172_30940 ENOG4108ZQS transposase BZ172_30950 ENOG4108MVM Transposase BZ172_31045 ENOG410607W Transposase BZ172_31080 ENOG4108QHK Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway