locus-tag class description G6O64_00005 ENOG4108TTM chaperone G6O64_00010 ENOG4108MY7 Fimbrial G6O64_00015 ENOG4108KK1 membrane protein AbrB duplication G6O64_00030 ENOG4107R7A Allophanate hydrolase subunit 2 G6O64_00035 ENOG4105P4J Allophanate hydrolase, subunit 1 G6O64_00040 ENOG4107QNR UPF0135 protein G6O64_00045 ENOG4105DUX Transporter G6O64_00055 ENOG4107SEY Conserved Protein G6O64_00060 ENOG4105CVP deoxyribo-dipyrimidine photolyase G6O64_00090 ENOG4105XIQ Protein of unknown function (DUF2517) G6O64_00115 ENOG4105C08 Histidine kinase G6O64_00120 ENOG4105EEX Two component transcriptional regulator (Winged helix family G6O64_00130 ENOG4105CXN decarboxylase G6O64_00135 ENOG4105D5Q Arginine ornithine antiporter G6O64_00140 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 G6O64_00145 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) G6O64_00150 ENOG4105EV9 Alpha Beta Hydrolase G6O64_00155 ENOG4105NNH LexA regulated protein G6O64_00160 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) G6O64_00170 ENOG41090R7 Ferric uptake G6O64_00175 ENOG4105GX6 (LipO)protein G6O64_00190 ENOG4105CI1 PTS System G6O64_00200 ENOG4105CE4 GlcNAc 6-P deacetylase G6O64_00205 ENOG4105E2R ROK family G6O64_00210 ENOG4105D4U had-superfamily hydrolase, subfamily iia G6O64_00220 ENOG4105CAQ asparagine synthetase G6O64_00260 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family G6O64_00270 ENOG4105C9A Phoh family G6O64_00280 ENOG4108JU5 Magnesium and cobalt efflux protein G6O64_00285 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) G6O64_00295 ENOG4107RP9 extracellular solute-binding protein, family 3 G6O64_00300 ENOG4105EAD ABC transporter G6O64_00305 ENOG4105DRP amino acid AbC transporter G6O64_00310 ENOG4105CDA abc transporter atp-binding protein G6O64_00320 ENOG4105F7F Chaperone G6O64_00325 ENOG4105QFC Hsc56 co-chaperone of HscC G6O64_00330 ENOG41069CF Protein of unknown function (DUF1266) G6O64_00335 ENOG4107JFD Sel1 repeat G6O64_00340 ENOG4105QFC Hsc56 co-chaperone of HscC G6O64_00345 ENOG41069CF Protein of unknown function (DUF1266) G6O64_00350 ENOG4105EUU Sel1 domain protein repeat-containing protein G6O64_00355 ENOG4107PAI alpha helical protein G6O64_00370 ENOG4105DJF DNA polymerase III, delta' subunit G6O64_00385 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) G6O64_00395 ENOG4105CJN penicillin-binding protein G6O64_00400 ENOG4105CNI cell division protein FtsW G6O64_00405 ENOG4105K6T rare lipoprotein A G6O64_00410 ENOG4105DZ1 carboxypeptidase G6O64_00425 ENOG41064T2 transcriptional regulator, lysR family G6O64_00435 ENOG4105VNT transposase (IS4 family) protein G6O64_00440 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) G6O64_00470 ENOG4105CEE C4-dicarboxylate transporter G6O64_00475 ENOG4106YYS transcriptional regulatory protein G6O64_00480 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism G6O64_00505 ENOG4105CI0 Citrate lyase G6O64_00510 ENOG4105CHY citrate lyase, alpha G6O64_00525 ENOG4107QPK )-transporter G6O64_00530 ENOG4105KTS ribonuclease G6O64_00535 ENOG4105NXH GreA GreB family elongation factor G6O64_00540 ENOG4105E2A Dehydrogenase G6O64_00545 ENOG4108U51 Universal stress protein G6O64_00550 ENOG4108JU3 Alkyl hydroperoxide reductase G6O64_00555 ENOG4105D3R alkyl hydroperoxide reductase G6O64_00560 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase G6O64_00575 ENOG4105GTN ParB Domain Protein Nuclease G6O64_00580 ENOG4105CHM Aminotransferase G6O64_00585 ENOG4107SCQ Iron-containing alcohol dehydrogenase G6O64_00590 ENOG4105VCD cytoplasmic protein G6O64_00595 ENOG4105D22 carbon starvation protein G6O64_00605 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase G6O64_00610 ENOG4105WQI isochorismatase G6O64_00615 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase G6O64_00620 ENOG4105E4F Isochorismate synthase G6O64_00625 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein G6O64_00635 ENOG4105DQ5 transport system permease protein G6O64_00640 ENOG4105TVJ transport system, permease G6O64_00645 ENOG4105E0A ABC, transporter G6O64_00650 ENOG4108QY5 Ferric enterobactin transport protein G6O64_00655 ENOG4105C0W non-ribosomal peptide synthetase G6O64_00660 ENOG41085A6 mbth domain-containing protein G6O64_00665 ENOG4105E93 esterase G6O64_00670 ENOG4107RNH Outer membrane receptor FepA G6O64_00675 ENOG4108TSE Transferase G6O64_00685 ENOG4107635 Hok Gef family protein G6O64_00700 ENOG4105MSB protein, conserved in bacteria G6O64_00705 ENOG4108RCM Nitroreductase G6O64_00710 ENOG4105CUY Mechanosensitive ion channel G6O64_00715 ENOG4105C85 amino acid G6O64_00720 ENOG4108IJF Heavy metal efflux pump, CzcA G6O64_00725 ENOG4105EP1 Efflux transporter rnd family, mfp subunit G6O64_00730 ENOG410624V efflux system protein G6O64_00735 ENOG4105ENJ RND efflux system, outer membrane lipoprotein G6O64_00740 ENOG4105CK6 Two component transcriptional regulator (Winged helix family G6O64_00745 ENOG4105GR3 Histidine kinase G6O64_00750 ENOG4105CS6 Rhs element vgr protein G6O64_00765 ENOG4105CNA YD repeat protein G6O64_00780 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit G6O64_00785 ENOG4105QUW G6O64_00820 ENOG4108ZI2 Fimbrial protein G6O64_00825 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) G6O64_00840 ENOG41060W2 glyoxylate carboligase G6O64_00845 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) G6O64_00865 ENOG4107REC cytoplasmic protein G6O64_00870 ENOG4105G5A Protein of unknown function (DUF2877) G6O64_00875 ENOG4105C5B carbamate kinase G6O64_00880 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit G6O64_00885 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) G6O64_00895 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) G6O64_00910 ENOG4105WQ3 Rna-binding protein G6O64_00935 ENOG4105CV6 ABC transporter, permease G6O64_00940 ENOG4108I0Y (ABC) transporter G6O64_00945 ENOG4108UJV acyl-CoA thioesterase i G6O64_00950 ENOG4105E1F short-chain dehydrogenase reductase G6O64_00955 ENOG4107QR8 Thioredoxin G6O64_00960 ENOG4105C4B ABC transporter, permease G6O64_00965 ENOG41083J0 (ABC) transporter G6O64_00970 ENOG4107QX8 SPFH domain, Band 7 family protein G6O64_00975 ENOG4105G5H Membrane G6O64_00980 ENOG4108Z6Z Transcriptional regulator G6O64_00985 ENOG4107RY6 amino acid G6O64_00990 ENOG4105CSV Glutaminase G6O64_00995 ENOG4105C59 p-type ATPase G6O64_01000 ENOG41081XE plasmid maintenance system antidote protein, xre family G6O64_01005 ENOG4105MBR gumn family G6O64_01010 ENOG4108Z66 YbaK ebsC protein G6O64_01015 ENOG4105CGH 5'-nucleotidase G6O64_01030 ENOG4105CKD glutathione-regulated potassium-efflux system protein G6O64_01035 ENOG4107RE1 Inosine-guanosine kinase G6O64_01070 ENOG4107QMP dna polymerase iii subunits gamma and tau G6O64_01080 ENOG4105WD1 Membrane G6O64_01085 ENOG4108URS primosomal replication protein n'' G6O64_01090 ENOG4106428 Protein of unknown function (DUF2496) G6O64_01095 ENOG4105EGS Mechanosensitive ion channel G6O64_01100 ENOG4107XI7 Tetr family transcriptional regulator G6O64_01105 ENOG4105C1P efflux transporter, rnd family, mfp subunit G6O64_01110 ENOG4105BZS acriflavin resistance protein G6O64_01115 ENOG4108UKR Biofilm formation regulator YbaJ G6O64_01120 ENOG4105KF5 hemolysin expression-modulating protein G6O64_01125 ENOG4108UW5 maltose o-acetyltransferase G6O64_01130 ENOG4105GSJ Inner membrane protein ylaC G6O64_01140 ENOG4105KCV RNA signal recognition particle 4.5S RNA G6O64_01150 ENOG41080UX Methyltransferase G6O64_01155 ENOG4108MNP Glycoprotein polysaccharide metabolism G6O64_01160 ENOG4105C29 acyl-CoA thioesterase G6O64_01165 ENOG4105BZU Histidine kinase G6O64_01170 ENOG4108YZA Nitrogen regulatory protein pii G6O64_01175 ENOG4105BZ1 (ABC) transporter G6O64_01180 ENOG4105BZ1 (ABC) transporter G6O64_01185 ENOG4108XM1 transcriptional regulator AsnC family G6O64_01195 ENOG4108NFA extracellular solute-binding protein G6O64_01205 ENOG4108TGP Thioesterase superfamily protein G6O64_01235 ENOG4105EIN peptidylprolyl cis-trans isomerase G6O64_01240 ENOG4105K70 DNA-binding protein G6O64_01245 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) G6O64_01265 ENOG4105M85 Bola protein G6O64_01270 ENOG4105IEY (LipO)protein G6O64_01275 ENOG4105EYM Major Facilitator superfamily G6O64_01280 ENOG4105E2S oxidase) subunit II G6O64_01285 ENOG4105BZ9 Cytochrome C oxidase, subunit I G6O64_01290 ENOG4105CCU oxidase (Subunit III) G6O64_01295 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) G6O64_01335 ENOG4107RDB Major Facilitator G6O64_01345 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) G6O64_01350 ENOG4107S0N DJ-1 family G6O64_01365 ENOG4105CTB Polyprenyl synthetase G6O64_01375 ENOG4105CPC Aldo Keto reductase G6O64_01380 ENOG4108ZAI phosphatidylglycerophosphatase a G6O64_01385 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) G6O64_01395 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) G6O64_01400 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) G6O64_01410 ENOG4108KIC (LipO)protein G6O64_01415 ENOG4105DRB nucleoside-specific channel-forming protein G6O64_01420 ENOG4105N1F Hnh endonuclease G6O64_01425 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) G6O64_01430 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) G6O64_01435 ENOG4105VIE preprotein translocase, subunit YajC G6O64_01455 ENOG4107R28 alpha amylase, catalytic region G6O64_01460 ENOG4105C85 amino acid G6O64_01465 ENOG4105CWM branched-chain amino acid transport system II carrier protein G6O64_01470 ENOG4105BZU Histidine kinase G6O64_01475 ENOG4105CK6 Two component transcriptional regulator (Winged helix family G6O64_01480 ENOG4107RH8 nuclease SbcCD subunit D G6O64_01485 ENOG4105EYH Exonuclease G6O64_01490 ENOG4105F27 Major Facilitator G6O64_01495 ENOG4105DKQ ROK family G6O64_01515 ENOG4105VNT transposase (IS4 family) protein G6O64_01525 ENOG4105HBA AroM protein G6O64_01530 ENOG4105SS3 G6O64_01545 ENOG4105II7 pyrroline-5-carboxylate reductase G6O64_01560 ENOG4105VIF phosphate starvation-inducible protein G6O64_01565 ENOG4105G6Z alkaline phosphatase G6O64_01580 ENOG4105CPF Cell wall formation (By similarity) G6O64_01585 ENOG4105UNH Membrane G6O64_01590 ENOG4105FR5 inner membrane protein YaiY G6O64_01595 ENOG4107QS8 (LipO)protein G6O64_01600 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 G6O64_01605 ENOG4107R6D beta-lactam binding protein AmpH G6O64_01610 ENOG4108PNB DNA-binding transcriptional regulator G6O64_01620 ENOG4105D52 delta-aminolevulinic acid dehydratase G6O64_01625 ENOG4105E2B Taurine dioxygenase G6O64_01630 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component G6O64_01640 ENOG4106FTQ Taurine ABC transporter, periplasmic G6O64_01650 ENOG4107W19 lmbE family G6O64_01665 ENOG4105SRB Uncharacterized protein yaiO G6O64_01685 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme G6O64_01690 ENOG4108SC4 )-transporter G6O64_01725 ENOG4105CV8 reductase G6O64_01730 ENOG4108KBJ Inner membrane protein YkgB G6O64_01735 ENOG41066GK UPF0379 protein ykgI G6O64_01740 ENOG4107QN2 dihydrolipoyl dehydrogenase G6O64_01745 ENOG4108K01 transcriptional regulator G6O64_01750 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) G6O64_01755 ENOG4107QR9 Iron-sulfur cluster binding protein G6O64_01760 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) G6O64_01775 ENOG4105N16 Protein of unknown function (DUF2877) G6O64_01780 ENOG4107R1Q Membrane protein FdrA G6O64_01785 ENOG4107REC cytoplasmic protein G6O64_01790 ENOG4105C5B carbamate kinase G6O64_01795 ENOG4105DZC cytosine deaminase G6O64_01800 ENOG4105DQ4 alcohol dehydrogenase G6O64_01825 ENOG4105E82 cytochrome subunit of dehydrogenase G6O64_01845 ENOG4105ETE Transcriptional regulator (LacI family G6O64_01905 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) G6O64_01915 ENOG4105FCK Membrane G6O64_01935 ENOG4105CIN aminoacyl-histidine dipeptidase G6O64_01940 ENOG4108S2Y peptide Chain Release factor G6O64_01950 ENOG410836F Transposase G6O64_01960 ENOG4108HYG acetyltransferase G6O64_01965 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) G6O64_01980 ENOG4108UK5 Transposase G6O64_01995 ENOG4108YS0 lipoprotein YafL G6O64_02005 ENOG4105VXN addiction module toxin, RelE StbE family G6O64_02010 ENOG4105F7V ErfK ybiS ycfS ynhG family protein G6O64_02015 ENOG4105E7A Glutamine amidotransferase G6O64_02025 ENOG4107QPN acyl-Coa dehydrogenase G6O64_02030 ENOG4108WN0 inhibitor of vertebrate lysozyme G6O64_02035 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase G6O64_02040 ENOG410600T transposase G6O64_02070 ENOG4105CS6 Rhs element vgr protein G6O64_02080 ENOG4108WC9 type VI secretion system effector, hcp1 family G6O64_02170 ENOG4105GMB type VI secretion system effector, hcp1 family G6O64_02185 ENOG410600K aminopeptidase G6O64_02195 ENOG4107RZZ dna polymerase iii epsilon subunit G6O64_02205 ENOG4105D1A Methyltransferase G6O64_02215 ENOG4105E9H Lytic Murein transglycosylase G6O64_02230 ENOG4105HEI LysR family (Transcriptional regulator G6O64_02235 ENOG4105CV8 reductase G6O64_02270 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase G6O64_02275 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) G6O64_02280 ENOG4108UMI ABC transporter, permease G6O64_02285 ENOG4105D01 (LipO)protein G6O64_02290 ENOG4108R8X outer membrane lipoprotein G6O64_02295 ENOG4108R96 Methyltransferase, YaeB family G6O64_02305 ENOG4108UY0 (LipO)protein G6O64_02310 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion G6O64_02320 ENOG4108VWS Yaeq family G6O64_02330 ENOG4105M1T rho-binding antiterminator G6O64_02335 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) G6O64_02340 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase G6O64_02345 ENOG4105CXN decarboxylase G6O64_02350 ENOG4105VNT transposase (IS4 family) protein G6O64_02360 ENOG4105C0B DNA polymerase III (alpha subunit) G6O64_02385 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) G6O64_02390 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) G6O64_02400 ENOG4105DZP Membrane-associated zinc metalloprotease G6O64_02405 ENOG4105KNE Phosphatidate cytidylyltransferase G6O64_02410 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) G6O64_02415 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) G6O64_02440 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) G6O64_02455 ENOG4105DIN metallophosphoesterase G6O64_02465 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR G6O64_02470 ENOG4105C0H protease G6O64_02495 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) G6O64_02500 ENOG4105EN6 Membrane G6O64_02525 ENOG4105S6R Iron-hydroxamate transporter permease subunit G6O64_02530 ENOG4105J76 Periplasmic binding protein G6O64_02535 ENOG4105E0A ABC, transporter G6O64_02555 ENOG4105BZ4 penicillin-binding protein G6O64_02560 ENOG4105CQ7 ATP-dependent helicase G6O64_02565 ENOG4107XID 2'-5' rna ligase G6O64_02585 ENOG4105DJ0 Poly(A) Polymerase G6O64_02590 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase G6O64_02600 ENOG4108VEV chaperone G6O64_02640 ENOG4105SYG Fimbrial protein G6O64_02645 ENOG4105SN2 fimbrial-like adhesin protein G6O64_02680 ENOG4108A32 Transposase G6O64_02690 ENOG4107BJW polysaccharide deacetylase G6O64_02695 ENOG4108YTN IIa component G6O64_02700 ENOG4105E3A (ABC) transporter G6O64_02705 ENOG4105DA5 (ABC) transporter G6O64_02710 ENOG41077A9 carbonic anhydrase G6O64_02715 ENOG4108UGV hypoxanthine phosphoribosyltransferase G6O64_02720 ENOG4105DZG Dehydrogenase G6O64_02725 ENOG4105E3B Multicopper oxidase G6O64_02730 ENOG4108ZRK uncharacterized protein yacC G6O64_02750 ENOG4107QIJ Aconitate hydratase 2 G6O64_02755 ENOG4108NST exported protein G6O64_02760 ENOG4107QN2 dihydrolipoyl dehydrogenase G6O64_02765 ENOG4107QSN dihydrolipoamide acetyltransferase G6O64_02770 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) G6O64_02775 ENOG41073TP transcriptional regulator G6O64_02780 ENOG4105C85 amino acid G6O64_02785 ENOG4106A72 regulatory protein AmpE G6O64_02790 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase G6O64_02795 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase G6O64_02800 ENOG4108ZUW Major pilin subunit G6O64_02820 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) G6O64_02835 ENOG4105M6F mutator MutT protein G6O64_02845 ENOG4108SR7 Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity) G6O64_02855 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) G6O64_02860 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) G6O64_02865 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) G6O64_02870 ENOG4105CPF Cell wall formation (By similarity) G6O64_02885 ENOG4105CNI cell division protein FtsW G6O64_02900 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) G6O64_02905 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) G6O64_02910 ENOG4105CJN penicillin-binding protein G6O64_02915 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) G6O64_02935 ENOG4107B7Y DNA-binding transcriptional regulator FruR G6O64_02945 ENOG4108ZP8 Acetolactate synthase small subunit G6O64_02950 ENOG4105C7K acetolactate synthase G6O64_02955 ENOG41064T2 transcriptional regulator, lysR family G6O64_03005 ENOG4105DP9 ABC transporter G6O64_03010 ENOG4106SMU thiamine transporter membrane protein G6O64_03020 ENOG4108KF1 Membrane G6O64_03025 ENOG41063TF transcriptional regulator (AraC G6O64_03040 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase G6O64_03045 ENOG4105CQ2 DNA polymerase G6O64_03055 ENOG4105D3G Pseudouridine synthase G6O64_03060 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) G6O64_03070 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) G6O64_03090 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) G6O64_03095 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) G6O64_03115 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein G6O64_03120 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase G6O64_03125 ENOG4105C10 Electron transfer flavoprotein G6O64_03160 ENOG4106YT9 Enoyl-CoA hydratase G6O64_03170 ENOG4108XNW Transcriptional activatory protein CaiF G6O64_03180 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain G6O64_03185 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain G6O64_03205 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase G6O64_03210 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) G6O64_03215 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) G6O64_03220 ENOG4105DTN riboflavin biosynthesis protein ribF G6O64_03225 ENOG410647N response to DNA damage stimulus G6O64_03260 ENOG41063Z6 transcriptional regulator, lysR family G6O64_03290 ENOG4105WI6 cell killing protein encoded within cryptic prophage G6O64_03310 ENOG4108QUJ UPF0174 protein YaaW G6O64_03315 ENOG4106HK8 GPR1 FUN34 yaaH family protein G6O64_03320 ENOG4108RIR Molybdenum cofactor biosynthesis protein G6O64_03325 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) G6O64_03350 ENOG41062C6 Protein of unknown function (DUF2502) G6O64_03355 ENOG4105D98 threonine synthase G6O64_03365 ENOG4105CFH Aspartokinase G6O64_03375 ENOG4106FVC RNA methyltransferase G6O64_03380 ENOG410759A G6O64_03385 ENOG41065U4 response regulator G6O64_03390 ENOG4105CT7 inner membrane cred family protein G6O64_03395 ENOG4105EB3 Histidine kinase G6O64_03400 ENOG4105E3W Two component transcriptional regulator (Winged helix family G6O64_03405 ENOG4108RH0 Crea protein G6O64_03410 ENOG4105UEI Transcriptional Regulator AraC Family G6O64_03420 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) G6O64_03430 ENOG4107SC1 transglycosylase G6O64_03435 ENOG4105C5H ABC transporter G6O64_03440 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase G6O64_03445 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) G6O64_03450 ENOG4105EAC phosphoserine phosphatase G6O64_03455 ENOG41062Z9 Membrane G6O64_03490 ENOG4105G0K glycine radical enzyme YjjI family G6O64_03495 ENOG41076CZ activating enzyme G6O64_03500 ENOG4105EYA deoxyribonuclease G6O64_03505 ENOG4108NRW Phospholipase, patatin family G6O64_03515 ENOG4105K3G Periplasmic Protein G6O64_03525 ENOG4105PAD Hydrolase G6O64_03530 ENOG4105KEG ribosomal-protein-alanine acetyltransferase G6O64_03535 ENOG4108WPU DNA polymerase III subunit psi G6O64_03570 ENOG4105YBH Protein of unknown function (DUF1435) G6O64_03575 ENOG4108819 ferric iron reductase G6O64_03580 ENOG4108T94 DNA-binding transcriptional activator BglJ G6O64_03605 ENOG4105DWK Membrane G6O64_03610 ENOG4107XM3 UPF0442 protein G6O64_03620 ENOG4106CVF DNA replication protein G6O64_03625 ENOG4105RI1 glycoprotein receptor G6O64_03635 ENOG4105CPQ Dehydrogenase G6O64_03640 ENOG410617M Transcriptional regulator G6O64_03655 ENOG4108V8F Transcriptional regulator, MarR family G6O64_03660 ENOG4105ERH Fumarylacetoacetate hydrolase G6O64_03665 ENOG4105C26 Dehydrogenase G6O64_03670 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase G6O64_03710 ENOG4105EFA 4-hydroxyphenylacetate G6O64_03715 ENOG4107UWN reductase G6O64_03720 ENOG4105D22 carbon starvation protein G6O64_03725 ENOG4105VCD cytoplasmic protein G6O64_03730 ENOG4105CKI cobalamin synthesis protein G6O64_03740 ENOG410836F Transposase G6O64_03760 ENOG4105C6F GntR Family Transcriptional Regulator G6O64_03765 ENOG4105DEI Mannitol dehydrogenase G6O64_03790 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria G6O64_03830 ENOG4108SF5 RNA Polymerase G6O64_03835 ENOG4108S3W Anti-feci sigma factor, fecr G6O64_03840 ENOG4105GAV receptor G6O64_03845 ENOG4108HUF Transporter G6O64_03850 ENOG4105DQ5 transport system permease protein G6O64_03855 ENOG4108IHU transport system permease protein G6O64_03860 ENOG4105E0A ABC, transporter G6O64_03885 ENOG4105DQ4 alcohol dehydrogenase G6O64_03890 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family G6O64_03895 ENOG4105CPQ Dehydrogenase G6O64_03900 ENOG4105CHR reductase G6O64_03905 ENOG4105C6Z Gluconate G6O64_03910 ENOG4105K2J Transcriptional regulator G6O64_03915 ENOG4105D7A ATP-binding protein G6O64_03920 ENOG4108K5H permease YjgP YjgQ family protein G6O64_03925 ENOG4108M8S permease YjgP YjgQ family protein G6O64_03935 ENOG4105MYG DNA polymerase iii, chi subunit G6O64_03945 ENOG4108M3P Membrane G6O64_03970 ENOG4108MJ3 acetyltransferase G6O64_03975 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) G6O64_04015 ENOG4108XFH Transcriptional regulator G6O64_04020 ENOG4105F6U Short-chain dehydrogenase reductase Sdr G6O64_04025 ENOG4108UQ8 endoribonuclease L-psp G6O64_04030 ENOG4107C93 pyrBI operon leader peptide G6O64_04045 ENOG4105KME endoribonuclease L-psp G6O64_04050 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic G6O64_04060 ENOG4105D4X repressor G6O64_04065 ENOG4105C5Y PTS System G6O64_04070 ENOG4105CG3 alpha amylase, catalytic region G6O64_04075 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase G6O64_04080 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) G6O64_04090 ENOG4105CMS peptidase U62, modulator of DNA gyrase G6O64_04100 ENOG4105DFU Cell wall formation (By similarity) G6O64_04110 ENOG41062B0 ABC transporter, permease G6O64_04115 ENOG4107R9N ABC transporter G6O64_04120 ENOG4105C2J ABC transporter G6O64_04125 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator G6O64_04130 ENOG4105F0N pyrophosphate phospho-hydrolase G6O64_04135 ENOG4108ZHD aig2 family G6O64_04140 ENOG4105MA0 exported protein G6O64_04145 ENOG4105CFU surface antigen G6O64_04155 ENOG4105C37 (CBS) domain G6O64_04160 ENOG41061GZ Protein of unknown function (DUF1107) G6O64_04165 ENOG4108UUE Transcriptional regulator G6O64_04175 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase G6O64_04180 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic G6O64_04185 ENOG4105KVH Transcriptional regulator G6O64_04190 ENOG4105ECR NmrA family G6O64_04195 ENOG4105DXC membrane G6O64_04205 ENOG4105C85 amino acid G6O64_04210 ENOG4108V1T peptidylprolyl cis-trans isomerase G6O64_04215 ENOG4105FHY Opacity-associated protein A G6O64_04235 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit G6O64_04245 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) G6O64_04265 ENOG4105R3P Inner membrane protein yagU G6O64_04310 ENOG4108MXZ Esterase G6O64_04315 ENOG4105WSB biofilm stress and motility protein A G6O64_04320 ENOG4105S17 UPF0379 protein yjfN G6O64_04325 ENOG4105CSU acyl-Coa dehydrogenase G6O64_04330 ENOG4106032 Glutathionylspermidine synthase G6O64_04335 ENOG4108KXT Conserved Protein G6O64_04345 ENOG4105C2N RNA methyltransferase TrmH family group 3 G6O64_04350 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) G6O64_04370 ENOG4105EPW hflc protein G6O64_04375 ENOG4107QJR hflk protein G6O64_04380 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) G6O64_04400 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase G6O64_04405 ENOG4105K8N protein family UPF0079, ATPase G6O64_04410 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) G6O64_04455 ENOG4105EGS Mechanosensitive ion channel G6O64_04470 ENOG4107SC7 Inner membrane transporter yjeM G6O64_04480 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) G6O64_04485 ENOG4105E33 succinate dehydrogenase G6O64_04500 ENOG41066YJ Beta-lactamase G6O64_04505 ENOG4105QNF Outer membrane lipoprotein G6O64_04510 ENOG4105KPY Small multidrug resistance protein G6O64_04515 ENOG4106BSU Entericidin B G6O64_04520 ENOG4107PEH Entericidin EcnA/B family G6O64_04530 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein G6O64_04550 ENOG4108ZVF (LipO)protein G6O64_04565 ENOG4105DVH amino acid G6O64_04570 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 G6O64_04575 ENOG4108IJ0 Aspartate ammonia-lyase G6O64_04580 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter G6O64_04595 ENOG4108SIC Transcriptional regulator G6O64_04615 ENOG4105VNT transposase (IS4 family) protein G6O64_04625 ENOG4105D5Q Arginine ornithine antiporter G6O64_04655 ENOG4105DUX Transporter G6O64_04660 ENOG4105CRK lysyL-tRNA synthetase G6O64_04675 ENOG410830R acetyltransferase G6O64_04680 ENOG4105VR1 Pfam:DUF1271 G6O64_04685 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism G6O64_04690 ENOG4108MRH transcriptional regulatory protein G6O64_04695 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter G6O64_04700 ENOG4107GFK fumarate G6O64_04730 ENOG4105F8D glycoside hydrolase family 4 G6O64_04735 ENOG4108K2B transcriptional regulator G6O64_04740 ENOG4105CXN decarboxylase G6O64_04745 ENOG4106ZGR Transcriptional regulator G6O64_04750 ENOG4105D5Q Arginine ornithine antiporter G6O64_04755 ENOG4105DIJ Phosphoethanolamine transferase G6O64_04760 ENOG4105XJC Two component transcriptional regulator (Winged helix family G6O64_04765 ENOG4105ECM Sensor protein basS pmrB G6O64_04775 ENOG4105CSH Transporter G6O64_04780 ENOG4108YIV G6O64_04785 ENOG4108F5E vimentin G6O64_04790 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA G6O64_04805 ENOG4105EHI Phosphonate ABC transporter, periplasmic G6O64_04815 ENOG4107RJJ Transcriptional regulator G6O64_04820 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG G6O64_04825 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH G6O64_04830 ENOG4105EKV Phosphonate metabolism protein G6O64_04835 ENOG4105FT8 Phosphonate metabolism G6O64_04840 ENOG4105ENV phosphonate C-P lyase system protein PhnK G6O64_04845 ENOG4105HRV phosphonate c-p lyase system protein phnl G6O64_04850 ENOG4105FD8 phosphonate metabolism protein PhnM G6O64_04855 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) G6O64_04860 ENOG410849A acetyltransferase, (GNAT) family G6O64_04865 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein G6O64_04875 ENOG4108YZG isomerase G6O64_04880 ENOG4105EUZ Beta-lactamase domain protein G6O64_04890 ENOG4105J12 Multidrug resistance protein mdtN G6O64_04895 ENOG4108MI0 Resistance protein G6O64_04900 ENOG4105ETP RND efflux system, outer membrane lipoprotein G6O64_04910 ENOG41082ND Uncharacterized protein yjcO G6O64_04915 ENOG4105CK2 sodium dicarboxylate symporter G6O64_04920 ENOG4108W0S formate-dependent nitrite reductase complex G6O64_04930 ENOG4108QKW cytochrome c-type biogenesis protein G6O64_04935 ENOG4105DVI reductase, NrfD G6O64_04940 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein G6O64_04945 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit G6O64_04955 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) G6O64_04975 ENOG4108Z4X TRANSCRIPTIONal G6O64_04980 ENOG4105C7N Xanthine uracil vitamin C permease G6O64_04985 ENOG4105EEQ Na H antiporter G6O64_05000 ENOG4108W3Q Transcriptional regulator G6O64_05005 ENOG4108M8H domain protein G6O64_05015 ENOG4108UUM single-stranded DNA-binding protein G6O64_05020 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) G6O64_05025 ENOG4105MSB protein, conserved in bacteria G6O64_05030 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme G6O64_05035 ENOG4105F0S class B acid phosphatase G6O64_05045 ENOG4105CGF Aromatic amino acid aminotransferase G6O64_05055 ENOG4105CDU Replicative dna helicase G6O64_05060 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein G6O64_05065 ENOG4105P4Z Phage shock protein G G6O64_05070 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) G6O64_05080 ENOG4105MYN Zinc uptake regulation protein G6O64_05085 ENOG4105VDW Csbd family G6O64_05090 ENOG4107R73 Mate efflux family protein G6O64_05100 ENOG41080IJ Diacylglycerol kinase G6O64_05135 ENOG4105EQR Transposase IS116 IS110 IS902 G6O64_05150 ENOG4107W52 maltose operon periplasmic protein G6O64_05160 ENOG4108IJ9 (ABC) transporter G6O64_05165 ENOG4107FKK extracellular solute-binding protein family 1 G6O64_05170 ENOG4105D56 permease protein G6O64_05175 ENOG4105EG2 ABC transporter, permease G6O64_05180 ENOG4107QNK )-transporter G6O64_05195 ENOG4105E3R (LipO)protein G6O64_05200 ENOG4108Q9C Periplasmic Protein G6O64_05205 ENOG4108MDC (LipO)protein G6O64_05215 ENOG4107QP8 phosphohexose isomerase G6O64_05220 ENOG4105CFH Aspartokinase G6O64_05225 ENOG4108ZR5 Conserved Protein G6O64_05230 ENOG4105FE9 pseudouridine synthase G6O64_05240 ENOG4105CHR reductase G6O64_05245 ENOG4108XCU pts system G6O64_05255 ENOG4105ETZ PTS System G6O64_05260 ENOG4105F3R pts system mannose fructose sorbose family iid G6O64_05275 ENOG4105EAM Na Pi-cotransporter G6O64_05280 ENOG4105C3R Methionine synthase G6O64_05285 ENOG41069M3 Transcriptional regulator G6O64_05315 ENOG4105K5X acetyltransferase G6O64_05345 ENOG4105C12 Phosphoribosylglycinamide synthetase G6O64_05350 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family G6O64_05355 ENOG4105BZU Histidine kinase G6O64_05360 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism G6O64_05365 ENOG4108T8B Protein of unknown function (DUF1481) G6O64_05375 ENOG4105R2J Conserved Protein G6O64_05410 ENOG4105D06 uba thif-type nad fad binding protein G6O64_05415 ENOG4105WHD thiamine biosynthesis protein ThiS G6O64_05425 ENOG4105D41 biosynthesis protein thiH G6O64_05460 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) G6O64_05465 ENOG4105PM1 preprotein translocase subunit SecE G6O64_05500 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase G6O64_05530 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) G6O64_05535 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) G6O64_05545 ENOG4108Y73 Membrane G6O64_05550 ENOG4105EJ2 Transcriptional regulator G6O64_05560 ENOG4105C5Q Transcriptional regulator G6O64_05575 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase G6O64_05590 ENOG4105DIJ Phosphoethanolamine transferase G6O64_05595 ENOG4106R3P AraC family transcriptional regulator G6O64_05600 ENOG4108XCZ PTS System G6O64_05605 ENOG4108AHH pyruvate formate lyase II activase G6O64_05620 ENOG4105DM4 PTS System G6O64_05625 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) G6O64_05630 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) G6O64_05635 ENOG4105DCT glycerol dehydrogenase G6O64_05640 ENOG4108XC3 NADH ubiquinone oxidoreductase G6O64_05645 ENOG4108Q5Y Membrane G6O64_05655 ENOG4105SYT Methylenetetrahydrofolate reductase G6O64_05660 ENOG4105CFH Aspartokinase G6O64_05665 ENOG4105C28 cystathionine G6O64_05675 ENOG4107S01 Repressor protein MetJ G6O64_05690 ENOG4105CNA YD repeat protein G6O64_05690 ENOG4105CNA YD repeat protein G6O64_05705 ENOG4105CNA YD repeat protein G6O64_05720 ENOG4105C25 Primosomal protein n' G6O64_05725 ENOG4105ETE Transcriptional regulator (LacI family G6O64_05730 ENOG41063M6 Cell Division Protein G6O64_05745 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase G6O64_05760 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) G6O64_05770 ENOG4105CBT Fructose-1,6-bisphosphatase G6O64_05775 ENOG4105DP0 ferredoxin-NADP reductase G6O64_05785 ENOG41065TG regulatoR G6O64_05790 ENOG4108VTS Membrane G6O64_05795 ENOG4105EBK exported protein G6O64_05810 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein G6O64_05825 ENOG4105FMW periplasmic G6O64_05830 ENOG4105E3W Two component transcriptional regulator (Winged helix family G6O64_05835 ENOG4105E0F Histidine kinase G6O64_05840 ENOG4108RPX mosc domain containing protein G6O64_05850 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) G6O64_05890 ENOG41064BA PTS system, fructose-specific, IIA component G6O64_05895 ENOG4105DM4 PTS System G6O64_05900 ENOG4105CN9 Peptidase m42 family protein G6O64_05905 ENOG4106C3V frv operon regulatory protein G6O64_05925 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) G6O64_05935 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein G6O64_05940 ENOG4108MG3 formate dehydrogenase G6O64_05950 ENOG41068KX affects formate dehydrogenase-N G6O64_05960 ENOG4105SUU thioesterase domain G6O64_05975 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 G6O64_05985 ENOG4105CSH Transporter G6O64_05995 ENOG4105CPQ Dehydrogenase G6O64_06000 ENOG4105D2M Aldolase G6O64_06005 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase G6O64_06015 ENOG4105VNT transposase (IS4 family) protein G6O64_06025 ENOG4105E98 transcriptional regulator DeoR family G6O64_06030 ENOG4105VNT transposase (IS4 family) protein G6O64_06035 ENOG4105CI3 gtp-binding protein typa G6O64_06040 ENOG4105C5F glutamine synthetase G6O64_06045 ENOG4105CUX Signal transduction histidine kinase G6O64_06050 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family G6O64_06055 ENOG4106FIY G6O64_06060 ENOG4105D4P Coproporphyrinogen iii oxidase G6O64_06065 ENOG4105ZR3 A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity) G6O64_06075 ENOG4105C2M dna polymerase I G6O64_06080 ENOG4106HNH Acyl-transferase G6O64_06095 ENOG4108Z33 Thiol disulfide Interchange Protein G6O64_06100 ENOG4105E27 serine threonine protein kinase G6O64_06105 ENOG4105PC1 Conserved Protein G6O64_06110 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) G6O64_06115 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b G6O64_06145 ENOG4108RR8 protoporphyrinogen oxidase G6O64_06150 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) G6O64_06155 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein G6O64_06165 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase G6O64_06175 ENOG4108EX3 reductase G6O64_06180 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) G6O64_06185 ENOG4105MDZ Transcriptional activator rfaH G6O64_06190 ENOG4105F8V Hydrolase, tatD family G6O64_06195 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) G6O64_06200 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) G6O64_06205 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) G6O64_06215 ENOG4105JC1 sterol-binding domain protein G6O64_06225 ENOG4105CGY Dna recombination protein G6O64_06230 ENOG4108I5U Uridine phosphorylase G6O64_06235 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) G6O64_06260 ENOG4105DZ2 Transcriptional regulator G6O64_06265 ENOG4105EMK carboxylate amino acid amine transporter G6O64_06270 ENOG4105DQF Hydrolase G6O64_06275 ENOG4108EUD Lysophospholipase G6O64_06280 ENOG410829K Lysine exporter protein (Lyse ygga) G6O64_06285 ENOG4105CCF Lysine exporter protein (Lyse ygga) G6O64_06290 ENOG4105C9U ATP-dependent DNA helicase RecQ G6O64_06295 ENOG4105HDD phospholipase G6O64_06300 ENOG4108VUY thioesterase Superfamily protein G6O64_06305 ENOG4105FR1 rard protein G6O64_06315 ENOG4107QUT magnesium and cobalt transport protein CorA G6O64_06340 ENOG4107QUT magnesium and cobalt transport protein CorA G6O64_06345 ENOG4108T58 Mg2 transport protein CorA G6O64_06355 ENOG4108T58 Mg2 transport protein CorA G6O64_06360 ENOG4107V4F S-adenosyl-l-methionine hydroxide adenosyltransferase G6O64_06365 ENOG4105C4R Atp-dependent dna helicase G6O64_06370 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant G6O64_06380 ENOG4105CT0 Protein of unknown function, DUF484 G6O64_06390 ENOG4105S7Z (LipO)protein G6O64_06400 ENOG4107T0K Adenylate cyclase G6O64_06410 ENOG41076E6 Uroporphyrinogen-III Synthase G6O64_06415 ENOG4105ECF c-methyltransferase G6O64_06420 ENOG410601J HemY protein G6O64_06425 ENOG4105ENH Sulfatase G6O64_06430 ENOG4105C4X radical SAM domain protein G6O64_06455 ENOG4105C85 amino acid G6O64_06465 ENOG4105DAD Could be involved in ECA polysaccharide chain elongation (By similarity) G6O64_06475 ENOG4105EGZ biosynthesis protein G6O64_06480 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase G6O64_06485 ENOG4108WJ1 acetyltransferase G6O64_06490 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) G6O64_06495 ENOG4105C1B dTDP-glucose 4-6-dehydratase G6O64_06500 ENOG4107QQG Dehydrogenase G6O64_06505 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase G6O64_06510 ENOG4105SFE lipopolysaccharide biosynthesis protein G6O64_06515 ENOG4105ESV Glycosyl transferase, family 4 G6O64_06520 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) G6O64_06545 ENOG4105C4R Atp-dependent dna helicase G6O64_06565 ENOG4105KQ5 peptidylprolyl cis-trans isomerase G6O64_06575 ENOG4105EMY transcriptional regulator G6O64_06580 ENOG4105C7B Threonine dehydratase G6O64_06590 ENOG4105CM2 brancheD-chain amino acid aminotransferase G6O64_06595 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit G6O64_06625 ENOG4105C0P Mg chelatase subunit ChlI G6O64_06645 ENOG4108WFC UPF0438 protein yifE G6O64_06685 ENOG4107EJG GntR family transcriptional regulator G6O64_06690 ENOG4105C0R drug resistance transporter emrb qaca subfamily G6O64_06695 ENOG4105ETE Transcriptional regulator (LacI family G6O64_06700 ENOG4108RVA ribokinase G6O64_06710 ENOG4105CNN ABC, transporter G6O64_06730 ENOG4105VNT transposase (IS4 family) protein G6O64_06735 ENOG4105DYC esterase G6O64_06745 ENOG4105CS2 ec 3.2.1.21 G6O64_06760 ENOG4105C5Y PTS System G6O64_06765 ENOG4105CID antiterminator G6O64_06770 ENOG4108UTW Plays a role in the regulation of phosphate uptake G6O64_06775 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) G6O64_06780 ENOG4105E2Z phosphate ABC transporter (Permease G6O64_06785 ENOG4105C8U phosphate abc transporter G6O64_06790 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) G6O64_06815 ENOG4108NAE Fimbrial chaperone protein G6O64_06835 ENOG4105VNT transposase (IS4 family) protein G6O64_06910 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) G6O64_06960 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation G6O64_06975 ENOG4105QTB Flavodoxin G6O64_06980 ENOG4108VVK transcriptional Regulator, AsnC G6O64_06990 ENOG4105EV2 VWA domain protein interacting with AAA ATPase G6O64_07005 ENOG4106S2D Transcriptional regulator G6O64_07010 ENOG4105CBN LysR family transcriptional regulator G6O64_07015 ENOG4107H3J ribonuclease G6O64_07020 ENOG4105CSH Transporter G6O64_07025 ENOG41066T0 asmA family G6O64_07030 ENOG4105CMB EAL domain-containing protein G6O64_07040 ENOG4105CS0 peptidase G6O64_07050 ENOG4105BZU Histidine kinase G6O64_07060 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) G6O64_07065 ENOG4107EEX Cellulose synthase regulator protein G6O64_07070 ENOG4107QZ7 Cellulose synthase catalytic subunit G6O64_07075 ENOG4107QZ7 Cellulose synthase catalytic subunit G6O64_07085 ENOG410661M cytoplasmic protein G6O64_07095 ENOG4105U74 cellulose biosynthesis protein BcsE G6O64_07100 ENOG4105WQA Cellulose biosynthesis protein BcsF G6O64_07105 ENOG4105D1V cellulose synthase operon protein YhjU G6O64_07140 ENOG4105C44 Serine transporter G6O64_07145 ENOG4108JQ7 (ABC) transporter G6O64_07150 ENOG4105C3U ABC transporter G6O64_07155 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component G6O64_07160 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component G6O64_07165 ENOG4105DEF Extracellular solute-binding protein, family 5 G6O64_07185 ENOG4105DIJ Phosphoethanolamine transferase G6O64_07190 ENOG4105FCD Major Facilitator G6O64_07195 ENOG4105EAX Putative lipase G6O64_07200 ENOG4108R3E Dna-3-methyladenine glycosylase i G6O64_07205 ENOG4105HNP -acetyltransferase G6O64_07210 ENOG4107QY8 reductase G6O64_07220 ENOG4108ZG0 Ompa motb domain protein G6O64_07230 ENOG4106JH6 (LipO)protein G6O64_07235 ENOG4105MVF Transcriptional regulator G6O64_07245 ENOG41060TC Hok gef cell toxic protein G6O64_07265 ENOG4105MEV Acyl-transferase G6O64_07270 ENOG4108Z12 YiaAB two helix domain-containing protein G6O64_07285 ENOG4108Z12 YiaAB two helix domain-containing protein G6O64_07290 ENOG410688U Inner membrane protein yiaB G6O64_07295 ENOG4105CMG Carbohydrate kinase G6O64_07300 ENOG4105CMG Carbohydrate kinase G6O64_07315 ENOG4105EM7 Selenocysteine-specific translation elongation factor G6O64_07325 ENOG4108U78 Glutathione S-transferase G6O64_07340 ENOG4105CNA YD repeat protein G6O64_07350 ENOG4105EFX secretion protein, HlyD family G6O64_07355 ENOG4105D70 Integrase catalytic subunit G6O64_07360 ENOG4105F5W AtP-binding protein G6O64_07365 ENOG4105FP6 Protein of unknown function (DUF3302) G6O64_07370 ENOG4105CTS PTS system mannitol-specific G6O64_07380 ENOG4105E61 Mannitol repressor protein G6O64_07390 ENOG4108YYI Protein of unknown function (DUF2810) G6O64_07400 ENOG4105EUR Domain-Containing protein G6O64_07405 ENOG4105DAA L-lactate G6O64_07410 ENOG41073TP transcriptional regulator G6O64_07420 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) G6O64_07425 ENOG4105D7W serine acetyltransferase G6O64_07440 ENOG4105VW4 glutaredoxin 3 G6O64_07445 ENOG4107YZP Rhodanese domain protein G6O64_07455 ENOG41063SB peptidase G6O64_07460 ENOG4105PXI polysaccharide deacetylase G6O64_07470 ENOG4105K64 Glycosyl transferase, family 2 G6O64_07480 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) G6O64_07490 ENOG4105XA0 heptosyltransferase ii G6O64_07495 ENOG4105D16 lipopolysaccharide heptosyltransferase i G6O64_07500 ENOG41068PG O-Antigen polymerase G6O64_07505 ENOG4105K64 Glycosyl transferase, family 2 G6O64_07510 ENOG4105X1N Glycosyl transferase family 8 G6O64_07520 ENOG4105X1N Glycosyl transferase family 8 G6O64_07525 ENOG4106AH0 Glycosyl Transferase G6O64_07530 ENOG4107543 (lipo)polysaccharide G6O64_07535 ENOG4107RJ7 Glycosyl transferase (Group 1 G6O64_07540 ENOG4105DKP glycosyl transferase, family 9 G6O64_07545 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase G6O64_07565 ENOG4105KDC 50s ribosomal protein l28 G6O64_07585 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase G6O64_07590 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) G6O64_07610 ENOG4105DSJ YicC domain protein G6O64_07615 ENOG4105F5P DNA-damage-inducible protein d G6O64_07620 ENOG4105EN6 Membrane G6O64_07630 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) G6O64_07640 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) G6O64_07645 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase G6O64_07650 ENOG4105CB5 ATP-dependent DNA helicase recG G6O64_07655 ENOG4105D6U Sodium Glutamate Symporter G6O64_07660 ENOG4105C2W permease G6O64_07665 ENOG4105JV1 AsmA family G6O64_07675 ENOG4105VNT transposase (IS4 family) protein G6O64_07705 ENOG4105DFP Integrase G6O64_07740 ENOG4105K89 arsenate reductase G6O64_07745 ENOG4107R5R arsenical pump membrane protein G6O64_07750 ENOG4105KBH arsR family transcriptional regulator G6O64_07765 ENOG4105DC8 reductase G6O64_07770 ENOG4105D6S protein involved in catabolism of external DNA G6O64_07775 ENOG4105DGW oligopeptidase A G6O64_07785 ENOG4105DUX Transporter G6O64_07800 ENOG4105CJ3 phosphate transporter G6O64_07805 ENOG4105CBX hi0933 family G6O64_07810 ENOG4107UNS conserved inner membrane protein G6O64_07825 ENOG4105D0S secretion protein (HlyD G6O64_07830 ENOG4105CJ1 ABC, transporter G6O64_07835 ENOG4105CMI transporter G6O64_07865 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component G6O64_07870 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component G6O64_07875 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein G6O64_07880 ENOG4107YAK holo-(acyl carrier protein) synthase 2 G6O64_07885 ENOG4105DSF transport protein G6O64_07890 ENOG4105F9N Major Facilitator Superfamily G6O64_07895 ENOG4108W1V Lipoprotein G6O64_07900 ENOG4105EX9 Membrane G6O64_07915 ENOG4107FS9 Membrane G6O64_07925 ENOG4105MG3 Membrane G6O64_07930 ENOG4106H78 methyltransferase G6O64_07935 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) G6O64_07940 ENOG4105CAK Cell division ATP-binding protein ftsE G6O64_07945 ENOG4105CRP Part of the ABC transporter FtsEX involved in G6O64_07950 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) G6O64_07955 ENOG4105CP9 extracellular ligand-binding receptor G6O64_07960 ENOG4105U59 -acetyltransferase G6O64_07965 ENOG4105CP9 extracellular ligand-binding receptor G6O64_07970 ENOG4105C32 Amino acid ABC transporter (Permease) G6O64_07975 ENOG4105CF8 branched-chain amino acid ABC transporter, permease G6O64_07980 ENOG4105C0Z ABC transporter G6O64_07985 ENOG4108IV0 ABC, transporter G6O64_07995 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component G6O64_08000 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component G6O64_08010 ENOG4107T6V glycerophosphoryl diester phosphodiesterase G6O64_08015 ENOG4105WC8 Conserved Protein G6O64_08030 ENOG4105WCN acetyltransferase G6O64_08035 ENOG4105D9R oxidoreductase G6O64_08040 ENOG4105C2I pirin domain protein G6O64_08045 ENOG4105DIQ Transcriptional regulator G6O64_08050 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family G6O64_08055 ENOG4105C6Z Gluconate G6O64_08060 ENOG4105C9U ATP-dependent DNA helicase RecQ G6O64_08080 ENOG41076UM multiple antibiotic resistance (MarC)-related protein G6O64_08085 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) G6O64_08110 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) G6O64_08140 ENOG4105C6V Glycerol-3-phosphate dehydrogenase G6O64_08155 ENOG4105E98 transcriptional regulator DeoR family G6O64_08190 ENOG4105VG0 50S ribosomal protein l34 G6O64_08205 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) G6O64_08215 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) G6O64_08220 ENOG4105VP5 Bacterial protein of unknown function (DUF937) G6O64_08225 ENOG410667J hydrolase G6O64_08235 ENOG4105EMF GntR family transcriptional regulator G6O64_08240 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 G6O64_08245 ENOG4108RTU Aldolase G6O64_08255 ENOG4105DJB Major Facilitator Superfamily G6O64_08265 ENOG4105D99 atp gtp-binding protein G6O64_08270 ENOG4105R2A (LipO)protein G6O64_08290 ENOG4105FDP GntR family transcriptional regulator G6O64_08295 ENOG4105CI1 PTS System G6O64_08310 ENOG4105D7V transposase G6O64_08315 ENOG4106DRA Inner membrane protein YidI G6O64_08320 ENOG4105VG5 Membrane G6O64_08325 ENOG4105JP4 Inner membrane protein yidG G6O64_08330 ENOG4105J13 transcriptional regulator G6O64_08335 ENOG4105E5M Multidrug resistance protein D G6O64_08350 ENOG4105C7K acetolactate synthase G6O64_08355 ENOG4105M71 acetolactate synthase 1 regulatory subunit G6O64_08360 ENOG4108KX4 response regulator G6O64_08365 ENOG4105BZU Histidine kinase G6O64_08370 ENOG4105CXY transporter G6O64_08375 ENOG4105CXY transporter G6O64_08395 ENOG4108SAJ Protein of unknown function (DUF1198) G6O64_08405 ENOG4105T8A Uncharacterized protein YicS G6O64_08410 ENOG4105D01 (LipO)protein G6O64_08430 ENOG4105D4K integrase catalytic G6O64_08435 ENOG4105MP0 transposase G6O64_08440 ENOG4105DQ6 Transposase G6O64_08475 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) G6O64_08480 ENOG4105DUU IucA IucC family protein G6O64_08585 ENOG4105Y4Z Outer Membrane Lipoprotein G6O64_08595 ENOG4105KT7 mgtC SapB transporter G6O64_08600 ENOG4105XXV Acid-resistance protein G6O64_08605 ENOG41060V2 Acid-resistance protein G6O64_08610 ENOG4108YK4 Acid-resistance membrane protein G6O64_08615 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci G6O64_08625 ENOG4105C1P efflux transporter, rnd family, mfp subunit G6O64_08630 ENOG4105BZS acriflavin resistance protein G6O64_08640 ENOG4108NKV transcriptional regulator G6O64_08645 ENOG4105CVK Glutamate decarboxylase G6O64_08650 ENOG4105CA0 peroxidase G6O64_08665 ENOG4105DYC esterase G6O64_08680 ENOG4106611 bacteriocin immunity G6O64_08700 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 G6O64_08705 ENOG4105C7N Xanthine uracil vitamin C permease G6O64_08715 ENOG4105E8Q phosphopantetheinyl transferase G6O64_08735 ENOG4105E0Y RtcB Protein G6O64_08750 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) G6O64_08755 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) G6O64_08760 ENOG4105C6Z Gluconate G6O64_08770 ENOG4105MJ2 Competence protein G6O64_08800 ENOG4105CE1 Ferrous iron transport protein b G6O64_08805 ENOG4105XFK Ferrous iron transport protein A G6O64_08810 ENOG4105BZM domain protein G6O64_08815 ENOG4108RRZ Transcription elongation factor GreB G6O64_08825 ENOG4105E0F Histidine kinase G6O64_08835 ENOG4108MAJ Membrane G6O64_08840 ENOG4108MAJ Membrane G6O64_08850 ENOG4105VEJ Heat shock protein G6O64_08855 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 G6O64_08860 ENOG4105DQY intracellular growth attenuator G6O64_08865 ENOG4107RK2 ADP-ribose diphosphatase NudE G6O64_08870 ENOG4108JQC penicillin-binding protein 1A G6O64_08875 ENOG4108U1Q Pilus assembly protein G6O64_08880 ENOG41065NF Fimbrial assembly family protein G6O64_08885 ENOG4105XPX DNA utilization protein HofO G6O64_08890 ENOG4105ITY Required for the use of extracellular DNA as a nutrient G6O64_08895 ENOG4105E4G Type IV pilus G6O64_08910 ENOG4105EGB membrane protein DamX G6O64_08915 ENOG4105DFE Dna adenine methylase G6O64_08920 ENOG4105DJV ribulose-phosphate 3-epimerase G6O64_08930 ENOG4105C31 Tryptophanyl-tRNA synthetase G6O64_08935 ENOG4108M21 G6O64_08940 ENOG4105RMW regulation of transcription, DNA-dependent G6O64_08955 ENOG41080QX K07048 phosphotriesterase-related protein G6O64_08960 ENOG4105MUZ Protein of unknown function DUF2620 G6O64_08965 ENOG4106M0N transport system permease protein G6O64_08970 ENOG4106PKC pyridoxal phosphate binding G6O64_08975 ENOG4105FDP GntR family transcriptional regulator G6O64_08980 ENOG4108KPW sugar kinase G6O64_08990 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine G6O64_08995 ENOG4107QHQ amino acid G6O64_09005 ENOG4105VYH G6O64_09015 ENOG4107V9H nitrite transporter G6O64_09020 ENOG4105WZK nitrite reductase NADPH small subunit G6O64_09025 ENOG4107QZF nitrite reductase NADPH large subunit G6O64_09035 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) G6O64_09045 ENOG4105MZU cell filamentation protein G6O64_09050 ENOG4105DDQ anthranilate synthase G6O64_09055 ENOG4105C8Y Acetylornithine aminotransferase G6O64_09060 ENOG410613R integral membrane protein, YccS YhfK family G6O64_09070 ENOG4108UKZ OsmC family G6O64_09075 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) G6O64_09085 ENOG4105DNZ Alpha Beta Hydrolase G6O64_09090 ENOG4105C5H ABC transporter G6O64_09105 ENOG4105VKU nucleicacid-binding protein G6O64_09110 ENOG4108YZY peptidylprolyl cis-trans isomerase G6O64_09120 ENOG4108V1T peptidylprolyl cis-trans isomerase G6O64_09125 ENOG4105WWK YheO domain protein G6O64_09135 ENOG4108ZKU Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) G6O64_09175 ENOG410899B May play a regulatory role under conditions of derepressed gsp gene expression G6O64_09190 ENOG410899B May play a regulatory role under conditions of derepressed gsp gene expression G6O64_09195 ENOG4107ACA Calcium-binding protein required for initiation of chromosome replication G6O64_09215 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) G6O64_09260 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) G6O64_09305 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) G6O64_09310 ENOG41067V7 50S ribosomal protein L36 G6O64_09340 ENOG4105VTS DnaJ-like, subfamily C G6O64_09345 ENOG4105W1Y Transcriptional regulator G6O64_09350 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system G6O64_09360 ENOG4105C1A potassium transporter peripheral membrane G6O64_09380 ENOG4105C79 DNA protecting protein DprA G6O64_09390 ENOG4108WI1 Dna topoisomerase G6O64_09405 ENOG4105SG3 Protein of unknown function (DUF1488) G6O64_09410 ENOG4108Z0R Transferase G6O64_09450 ENOG4105CDA abc transporter atp-binding protein G6O64_09455 ENOG4105DRP amino acid AbC transporter G6O64_09485 ENOG4105C1P efflux transporter, rnd family, mfp subunit G6O64_09490 ENOG4108XG4 DNA-binding transcriptional regulator G6O64_09495 ENOG41061ME transport protein G6O64_09500 ENOG4105CEC DNA methylase N-4 N-6 G6O64_09510 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) G6O64_09520 ENOG4108IA2 Sodium pantothenate symporter G6O64_09525 ENOG4105RG0 Membrane G6O64_09530 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase G6O64_09535 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein G6O64_09540 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family G6O64_09545 ENOG41062P1 Diguanylate cyclase phosphodiesterase G6O64_09555 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) G6O64_09560 ENOG4105VQ7 Rod shape-determining protein MreD G6O64_09570 ENOG4105C03 ribonuclease G6O64_09575 ENOG4105QD6 exported protein G6O64_09580 ENOG4105D1U peptidase U62 modulator of DNA gyrase G6O64_09590 ENOG4105ZQC membrane protein AaeX G6O64_09605 ENOG4105UNR (Barnase) inhibitor G6O64_09610 ENOG4105RID UPF0379 protein yhcN G6O64_09625 ENOG4105VNT transposase (IS4 family) protein G6O64_09630 ENOG4105C0H protease G6O64_09635 ENOG4105C0H protease G6O64_09640 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III G6O64_09645 ENOG4105D6Z AFG1 family ATPase G6O64_09660 ENOG4107MKT Stringent starvation protein a G6O64_09665 ENOG4105KB2 stringent starvation protein b G6O64_09670 ENOG4105CEE C4-dicarboxylate transporter G6O64_09685 ENOG4105JHE Major Facilitator Superfamily G6O64_09700 ENOG4108R66 Conserved Protein G6O64_09710 ENOG4105DFS Conserved Protein G6O64_09715 ENOG4105BZ8 glutamate synthase G6O64_09720 ENOG4105CBC glutamate synthase G6O64_09725 ENOG4105N5T Radical SAM Protein G6O64_09730 ENOG4105BZU Histidine kinase G6O64_09735 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain G6O64_09745 ENOG4108NIH transferase activity, transferring phosphorus-containing groups G6O64_09750 ENOG41080Z8 PHOSPHOCARRIER protein G6O64_09760 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN G6O64_09765 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA G6O64_09770 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) G6O64_09775 ENOG4108IUZ ABC transporter G6O64_09780 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA G6O64_09785 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) G6O64_09790 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase G6O64_09795 ENOG4105C2X Arabinose 5-phosphate isomerase G6O64_09800 ENOG4105FEU K -dependent Na -Ca exchanger G6O64_09805 ENOG4105DHJ ABC, transporter G6O64_09810 ENOG4105CY3 ABC transporter, permease G6O64_09815 ENOG4107PE3 Mammalian cell entry related domain protein G6O64_09820 ENOG4105E3I toluene tolerance G6O64_09825 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane G6O64_09830 ENOG4105VFK BolA family G6O64_09840 ENOG4105HVQ Regulatory factor of maltose metabolism G6O64_09845 ENOG4105EAH synthase G6O64_09860 ENOG4105QYV Membrane G6O64_09870 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase G6O64_09875 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) G6O64_09880 ENOG4105HBR Rna-binding protein G6O64_09890 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) G6O64_09895 ENOG4105EEI dihydropteroate synthase G6O64_09905 ENOG4105NTZ Preprotein translocase subunit SecG G6O64_09915 ENOG4105DIJ Phosphoethanolamine transferase G6O64_09945 ENOG4105CHV Transcription elongation factor NusA G6O64_09985 ENOG4105C1J atp-dependent rna helicase G6O64_09990 ENOG4105CIC tryptophan-specific transport protein G6O64_09995 ENOG4105DEN Luciferase family G6O64_10015 ENOG4108YYD acetyltransferase G6O64_10030 ENOG4107R7Y intracellular protease Pfpi family G6O64_10035 ENOG4105K4T epimerase G6O64_10040 ENOG4107S21 permease G6O64_10045 ENOG4105W4M Transport-associated protein G6O64_10065 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) G6O64_10085 ENOG4105CW0 outer membrane usher protein G6O64_10100 ENOG4105ZEG Suppressor protein G6O64_10115 ENOG4105CTX dehydratase G6O64_10120 ENOG4105DJB Major Facilitator Superfamily G6O64_10130 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase G6O64_10135 ENOG4105BZW Glycerate kinase G6O64_10160 ENOG410811B TRANSCRIPTIONal G6O64_10165 ENOG4105C7B Threonine dehydratase G6O64_10175 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) G6O64_10180 ENOG4105C6N Formate acetyltransferase G6O64_10185 ENOG4105KME endoribonuclease L-psp G6O64_10190 ENOG4105EJQ L-serine dehydratase G6O64_10195 ENOG4105C44 Serine transporter G6O64_10205 ENOG4106D80 Uncharacterized protein YhaL G6O64_10210 ENOG4108CNN domain protein G6O64_10220 ENOG4105KAF membrAne G6O64_10225 ENOG4105KAF membrAne G6O64_10230 ENOG4105CHF Glutathione S-transferase G6O64_10235 ENOG4108VBZ doxx family G6O64_10240 ENOG4105YJD G6O64_10245 ENOG41090KG Inner membrane protein YqjE G6O64_10250 ENOG4105NE1 Conserved Protein G6O64_10255 ENOG4105WAY exported protein G6O64_10260 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) G6O64_10265 ENOG4106W5V Membrane G6O64_10270 ENOG4107YCY Transcriptional regulator G6O64_10330 ENOG4105CTX dehydratase G6O64_10335 ENOG4105P66 Membrane G6O64_10340 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) G6O64_10355 ENOG4105HDK L-asparaginase G6O64_10360 ENOG4105K33 Periplasmic Protein G6O64_10365 ENOG41090ED Protein with unknown function (DUF469) G6O64_10375 ENOG4105CEN a g-specific adenine glycosylase G6O64_10390 ENOG4105EAA nucleoside G6O64_10405 ENOG4105CXN decarboxylase G6O64_10410 ENOG4108UQV Membrane G6O64_10470 ENOG4105I1J Autotransporter G6O64_10490 ENOG4108S55 polysaccharide biosynthesis protein G6O64_10495 ENOG4106FPV ATP-binding protein YghR G6O64_10500 ENOG4108NDC ATP-binding protein yghS G6O64_10505 ENOG4108GH0 ATP-binding protein yghT G6O64_10520 ENOG4105FK9 beta-D-galactosidase beta subunit G6O64_10530 ENOG4105VNT transposase (IS4 family) protein G6O64_10535 ENOG4105CQ4 Transcriptional regulator G6O64_10540 ENOG4108Y51 tRNA-binding protein G6O64_10550 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor G6O64_10555 ENOG4105NTW Transcriptional regulator G6O64_10560 ENOG4105Q26 Siderophore-interacting protein G6O64_10580 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) G6O64_10585 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) G6O64_10610 ENOG4106DSS Tartrate dehydratase subunit alpha G6O64_10625 ENOG4107ZVW dihydroneopterin aldolase G6O64_10640 ENOG4106MWK domain protein G6O64_10645 ENOG4105I7R Adenylate cyclase G6O64_10670 ENOG4107S78 Band 7 protein G6O64_10675 ENOG4105PV3 Inner membrane protein yqiJ G6O64_10690 ENOG4108MY7 Fimbrial G6O64_10695 ENOG4108TTM chaperone G6O64_10715 ENOG4105H8W Fimbrial protein G6O64_10720 ENOG4105W0Z cytoplasmic protein G6O64_10740 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b G6O64_10745 ENOG4106032 Glutathionylspermidine synthase G6O64_10755 ENOG4105DFG type I secretion outer membrane protein G6O64_10760 ENOG41087AY ADP-Ribose pyrophosphatase G6O64_10765 ENOG4108SX3 cytoplasmic protein G6O64_10770 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) G6O64_10775 ENOG4105IPS esterase G6O64_10780 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) G6O64_10785 ENOG4105VRH Antibiotic biosynthesis monooxygenase G6O64_10790 ENOG4105NF4 modulator of drug activity G6O64_10795 ENOG4105DHQ Histidine kinase G6O64_10800 ENOG4105XJC Two component transcriptional regulator (Winged helix family G6O64_10805 ENOG4105H4F exported protein G6O64_10810 ENOG4105F4I Transcriptional regulator G6O64_10815 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) G6O64_10820 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase G6O64_10825 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) G6O64_10830 ENOG4105CCT upf0313 protein G6O64_10840 ENOG4105ZKC Conserved Protein G6O64_10850 ENOG4105CV8 reductase G6O64_10855 ENOG4108I6A alcohol dehydrogenase G6O64_10860 ENOG4105CF7 AraC family transcriptional regulator G6O64_10865 ENOG4108K81 inner membrane protein YghB G6O64_10870 ENOG4105C28 cystathionine G6O64_10875 ENOG4105CWK Biopolymer transport protein, ExbB G6O64_10880 ENOG4108ZZF transport protein (ExbD) G6O64_10885 ENOG4105CYX Short-chain dehydrogenase reductase Sdr G6O64_10895 ENOG4105CPC Aldo Keto reductase G6O64_10905 ENOG410900S Protein of unknown function (DUF2623) G6O64_10910 ENOG4105E3S small subunit G6O64_10915 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein G6O64_10920 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit G6O64_10925 ENOG4105DPX Hydrogenase, large subunit G6O64_10930 ENOG4108USZ hydrogenase G6O64_10935 ENOG4108WGS hydrogenase 2-specific chaperone G6O64_10945 ENOG41082MF Hydrogenase assembly chaperone hypC hupF G6O64_10950 ENOG4105CYM Glutathione S-transferase G6O64_10955 ENOG4106032 Glutathionylspermidine synthase G6O64_10965 ENOG4105CJ3 phosphate transporter G6O64_10970 ENOG4108GH0 ATP-binding protein yghT G6O64_11010 ENOG4107WCA isomerase G6O64_11015 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase G6O64_11020 ENOG4108Z3N Transcriptional regulator G6O64_11025 ENOG4105R48 this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase G6O64_11035 ENOG4108VKG metal-dependent hydrolase G6O64_11040 ENOG4108UB4 uncharacterized protein ygjQ G6O64_11045 ENOG4105EE0 oxidoreductase G6O64_11050 ENOG4105DU1 integral membrane protein, terc G6O64_11090 ENOG4105CSA Coproporphyrinogen iii oxidase G6O64_11095 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) G6O64_11105 ENOG4108VIA integral membrane protein G6O64_11110 ENOG4105DFA alanine racemase domain protein G6O64_11115 ENOG4105CZX twitching motility protein G6O64_11130 ENOG4105D7Z glutathione synthase G6O64_11135 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) G6O64_11140 ENOG4105RWS endonuclease I G6O64_11150 ENOG4107QNK )-transporter G6O64_11170 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) G6O64_11180 ENOG4108K0D peptidase, M48 G6O64_11185 ENOG4105CV1 Transketolase (EC 2.2.1.1) G6O64_11190 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia G6O64_11210 ENOG4107Z1W Fructose transport system kinase G6O64_11215 ENOG4108JJB ABC transporter G6O64_11220 ENOG4108JJB ABC transporter G6O64_11250 ENOG4105D2N Aldolase G6O64_11255 ENOG4105D64 Mechanosensitive ion channel G6O64_11260 ENOG4108ZUB Lysine exporter protein (Lyse ygga) G6O64_11265 ENOG4105MPN Membrane G6O64_11285 ENOG4105CYC Transferase G6O64_11290 ENOG4108M7F enoyl-CoA hydratase isomerase G6O64_11295 ENOG4105DJT lAO AO transport system ATPase G6O64_11300 ENOG4105D5P Methylmalonyl-coA mutase G6O64_11315 ENOG4108JQ1 Dehydrogenase G6O64_11330 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase G6O64_11350 ENOG4107RAQ aminopeptidase G6O64_11355 ENOG4105D0A hydroxylase G6O64_11360 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family G6O64_11385 ENOG4105CYX Short-chain dehydrogenase reductase Sdr G6O64_11390 ENOG4105CS2 ec 3.2.1.21 G6O64_11400 ENOG4108UT2 hemolysin iii G6O64_11410 ENOG4105Y75 tpr repeat protein G6O64_11415 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB G6O64_11420 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) G6O64_11425 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) G6O64_11430 ENOG4105T95 Thiol disulfide interChange protein G6O64_11435 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) G6O64_11465 ENOG4105C2W permease G6O64_11475 ENOG4105BZ8 glutamate synthase G6O64_11480 ENOG4108R8B oxidoreductase Fe-S subunit G6O64_11490 ENOG4107QUY Guanine deaminase G6O64_11495 ENOG4105C7W Xanthine dehydrogenase G6O64_11500 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase G6O64_11505 ENOG4107UUR Chlorohydrolase aminohydrolase G6O64_11530 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase G6O64_11535 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC G6O64_11540 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family G6O64_11545 ENOG4105C5B carbamate kinase G6O64_11555 ENOG4107S4Y M20 DapE family protein YgeY G6O64_11560 ENOG4107RCH Diaminopropionate ammonia-lyase G6O64_11565 ENOG4105IW6 Carbamoyltransferase G6O64_11570 ENOG4108JUB Transcriptional regulator G6O64_11575 ENOG4108UTP (2Fe-2S)-binding domain protein G6O64_11580 ENOG4108HR6 Dehydrogenase G6O64_11585 ENOG4105C7W Xanthine dehydrogenase G6O64_11590 ENOG4108K5P (LipO)protein G6O64_11610 ENOG4108YAB Invasion protein G6O64_11630 ENOG4105FV3 G6O64_11635 ENOG4108TC1 Transcriptional regulator G6O64_11650 ENOG4105ISV protein with bipartite regulator domain G6O64_11655 ENOG4108MHD transport protein G6O64_11660 ENOG4105CHU acetyl-coa acetyltransferase G6O64_11670 ENOG4105CHR reductase G6O64_11675 ENOG4107QNK )-transporter G6O64_11685 ENOG4105RQF LysR family Transcriptional regulator G6O64_11695 ENOG41060NJ transcriptional regulator G6O64_11710 ENOG4105CPC Aldo Keto reductase G6O64_11725 ENOG4105SUV lipoprotein YgdR G6O64_11730 ENOG4105EE5 Membrane protein terC G6O64_11745 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase G6O64_11760 ENOG4105IPU prepilin peptidase dependent protein A G6O64_11765 ENOG4105JCS prepilin peptidase dependent protein G6O64_11770 ENOG4105SEN Protein of unknown function (DUF2509) G6O64_11775 ENOG4105RVB Prepilin peptidase dependent protein c G6O64_11780 ENOG4105DSY exodeoxyribonuclease V, gamma G6O64_11785 ENOG4107QXK peptidase G6O64_11790 ENOG4107QKA exodeoxyribonuclease V beta G6O64_11795 ENOG4107QYX exodeoxyribonuclease v alpha G6O64_11800 ENOG4108EKC n-acetylglutamate synthase G6O64_11805 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase G6O64_11825 ENOG4105CA3 membrane-bound lytic murein transglycosylase G6O64_11830 ENOG4105CUZ uba thif-type nad fad binding protein G6O64_11835 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) G6O64_11840 ENOG4105C9B Cysteine desulfurase G6O64_11845 ENOG4105M5B (LipO)protein G6O64_11850 ENOG4105ETT transcriptional Regulator, LysR family G6O64_11855 ENOG4105M08 Membrane G6O64_11865 ENOG4107EDW L-fucose operon activator G6O64_11875 ENOG4105CMG Carbohydrate kinase G6O64_11885 ENOG4105EDR glucose galactose transporter G6O64_11890 ENOG4107W7X Aldolase G6O64_11895 ENOG4105C0A alcohol dehydrogenase G6O64_11905 ENOG4105EJQ L-serine dehydratase G6O64_11910 ENOG4105C44 Serine transporter G6O64_11915 ENOG4105EWT decarboxylase family G6O64_11930 ENOG4105WP7 tRNA pseudouridine synthase C G6O64_11935 ENOG4105DR9 pseudouridine synthase G6O64_11940 ENOG4105QDK Flavodoxin G6O64_11945 ENOG4105DJB Major Facilitator Superfamily G6O64_11950 ENOG4105EQX glucarate dehydratase G6O64_11955 ENOG4105EQX glucarate dehydratase G6O64_11960 ENOG4105BZU Histidine kinase G6O64_11970 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) G6O64_11975 ENOG4106A2Z transcriptional regulator antitoxin, MazE G6O64_11980 ENOG4105MZG transcriptional modulator of maze toxin, mazf G6O64_11985 ENOG4105DXN mazG family G6O64_12000 ENOG4105VNT transposase (IS4 family) protein G6O64_12010 ENOG4105HA9 of methanol dehydrogenase type G6O64_12025 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) G6O64_12040 ENOG4108ITV Inner membrane protein yqcE G6O64_12050 ENOG4107R3A FAD linked oxidase domain protein G6O64_12055 ENOG4105C54 Major Facilitator superfamily G6O64_12060 ENOG4106IKH Electron transfer flavoprotein G6O64_12065 ENOG4105YBM electron transfer flavoprotein subunit ygcQ G6O64_12070 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator G6O64_12075 ENOG4105WQV ferredoxin-like protein G6O64_12080 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase G6O64_12085 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase G6O64_12105 ENOG4107635 Hok Gef family protein G6O64_12135 ENOG41060M0 Crispr-associated protein, cse4 family G6O64_12140 ENOG4108VWQ crispr-associated protein G6O64_12150 ENOG410836F Transposase G6O64_12165 ENOG4105PWE CRISPR-associated protein cas2 G6O64_12170 ENOG4108MXK alkaline phosphatase isozyme conversion G6O64_12175 ENOG4105C11 sulfate adenylyltransferase), subunit 2 G6O64_12190 ENOG4105N0Z inner membrane protein ygbE G6O64_12225 ENOG4108K5P (LipO)protein G6O64_12230 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) G6O64_12235 ENOG4105C6Z Gluconate G6O64_12240 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) G6O64_12245 ENOG4105FB2 class II Aldolase G6O64_12250 ENOG4105G63 Type III effector Hrp-dependent G6O64_12255 ENOG4105ZXK Dehydrogenase G6O64_12260 ENOG4105MVE transcriptional regulator G6O64_12290 ENOG4105VXR cytoplasmic protein G6O64_12300 ENOG4105C45 hydrogenase expression formation protein (HypE) G6O64_12305 ENOG4105CQS hydrogenase expression formation protein HypD G6O64_12310 ENOG41083WG hydrogenase assembly chaperone G6O64_12315 ENOG4107RSS Hydrogenase accessory protein HypB G6O64_12320 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) G6O64_12325 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA G6O64_12330 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) G6O64_12335 ENOG4107R30 NADH dehydrogenase G6O64_12340 ENOG4107TDF Formate hydrogenlyase subunit 4 G6O64_12345 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) G6O64_12350 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit G6O64_12355 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit G6O64_12360 ENOG4105I6X formate hydrogenlyase maturation G6O64_12365 ENOG4108MG9 hydrogenase 3 maturation protease G6O64_12375 ENOG4105RVE Uncharacterized protein conserved in bacteria (DUF2136) G6O64_12380 ENOG4108Z3N Transcriptional regulator G6O64_12385 ENOG4105CS2 ec 3.2.1.21 G6O64_12390 ENOG4105C5Y PTS System G6O64_12395 ENOG4105DDV Transcriptional regulator (LacI family G6O64_12400 ENOG4108RC0 Electron transport protein G6O64_12405 ENOG4105C8H hydrogenase maturation protein Hypf G6O64_12430 ENOG410804X Transcriptional regulator G6O64_12435 ENOG4105J92 DNA-binding transcriptional activator GutM G6O64_12445 ENOG4105VI0 Pts system, glucitol sorbitol-specific G6O64_12450 ENOG4105DZY Pts system, glucitol sorbitol-specific G6O64_12455 ENOG410787A Pts system, glucitol sorbitol-specific G6O64_12460 ENOG4105CVE Lytic murein transglycosylase G6O64_12465 ENOG4107TH8 cina domain protein G6O64_12485 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) G6O64_12515 ENOG4107VXZ Hydrolase G6O64_12520 ENOG4105W39 Membrane G6O64_12535 ENOG4105C0R drug resistance transporter emrb qaca subfamily G6O64_12540 ENOG4105CW7 secretion protein, HlyD family G6O64_12545 ENOG4105NTK Transcriptional repressor Mpra G6O64_12555 ENOG4105ZED uncharacterized protein ygaH G6O64_12560 ENOG4108UMN azlc family G6O64_12570 ENOG4105GIJ Glycine betaine G6O64_12575 ENOG4108HQS Glycine betaine G6O64_12580 ENOG4108IJ7 Glycine betaine G6O64_12585 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) G6O64_12590 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) G6O64_12600 ENOG4105WAZ (Glutaredoxin-like protein) NrdH G6O64_12605 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) G6O64_12610 ENOG4108WMJ Protein of unknown function (DUF2002) G6O64_12615 ENOG4108RNS Exports L-alanine (By similarity) G6O64_12625 ENOG4108X73 DNA- binding protein G6O64_12630 ENOG4108V62 Rhodanese domain protein G6O64_12635 ENOG41080HT Transcriptional regulator, arsr family G6O64_12640 ENOG4105VPI YqaE family transport protein G6O64_12645 ENOG4109066 lysm domain bon superfamily protein G6O64_12650 ENOG4108PVQ transcriptional regulator G6O64_12655 ENOG4105C85 amino acid G6O64_12660 ENOG4108JPW Aminotransferase G6O64_12665 ENOG4105C26 Dehydrogenase G6O64_12670 ENOG4105D5U fad dependent oxidoreductase G6O64_12675 ENOG4105EK3 May be involved in the control of utilization of gamma- aminobutyric acid (By similarity) G6O64_12680 ENOG4105E54 alpha-amylase G6O64_12735 ENOG4105CDU Replicative dna helicase G6O64_12745 ENOG4105KSK (crossover) junction endodeoxyribonuclease G6O64_12750 ENOG4105HRS Antitermination protein G6O64_12780 ENOG4105QFS Lysis protein S homolog from lambdoid prophage G6O64_12785 ENOG4105KUS lysozyme G6O64_12790 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 G6O64_12805 ENOG4105CAR Terminase, large subunit G6O64_12835 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) G6O64_12840 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) G6O64_12855 ENOG4108JU6 CBS domain protein G6O64_12860 ENOG4106KVJ cytochrome C assembly protein G6O64_12865 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY G6O64_12890 ENOG41090EK ompa motb domain protein G6O64_12910 ENOG4108KHX Diguanylate cyclase G6O64_12925 ENOG4108WS1 G6O64_12935 ENOG4105QP9 Protein of unknown function (DUF2799) G6O64_12940 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) G6O64_12945 ENOG4105EHE chorismate mutase- prephenate dehydrogenase G6O64_12950 ENOG4105CQC Prephenate dehydratase G6O64_12960 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA G6O64_12965 ENOG4105VNT transposase (IS4 family) protein G6O64_12970 ENOG4105VDB UPF0125 protein G6O64_12975 ENOG4108Z1B Cyclase dehydrase G6O64_12995 ENOG4108X9F tail fiber protein G6O64_13005 ENOG4105Y9F tail fiber protein G6O64_13010 ENOG4105Y0G tail protein G6O64_13015 ENOG4108T86 baseplate J family protein G6O64_13075 ENOG4105TKZ Tail Sheath G6O64_13090 ENOG4105VNT transposase (IS4 family) protein G6O64_13095 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane G6O64_13100 ENOG4105C34 Pseudouridine synthase G6O64_13105 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase G6O64_13110 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit G6O64_13135 ENOG4105CSH Transporter G6O64_13140 ENOG4105T42 (LipO)protein G6O64_13145 ENOG4105JIM Phosphatidylserine synthase G6O64_13150 ENOG4105CD5 CoA-binding domain protein G6O64_13155 ENOG4106IUH DTW domain containing protein G6O64_13160 ENOG4105K63 Thioredoxin G6O64_13165 ENOG4105EIB trna rrna methyltransferase G6O64_13185 ENOG41090KR LysR family transcriptional Regulator G6O64_13190 ENOG4105C1J atp-dependent rna helicase G6O64_13220 ENOG4105EMN RNA polymerase sigma factor G6O64_13225 ENOG41069PW sigma-e factor negative regulatory protein G6O64_13230 ENOG4105VQK sigma E regulatory protein, MucB RseB G6O64_13235 ENOG4105WMJ Positive regulator of sigma E, RseC MucC G6O64_13245 ENOG4105C3F Signal peptidase i G6O64_13280 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding G6O64_13290 ENOG410607W Transposase G6O64_13355 ENOG4107CBI conjugal transfer fertility inhibition protein G6O64_13385 ENOG4108YXQ IS66 Orf2 family protein G6O64_13390 ENOG4105E5H Transposase G6O64_13405 ENOG41063SR receptor G6O64_13475 ENOG4108YXQ IS66 Orf2 family protein G6O64_13505 ENOG4106G6Q Transcriptional regulator G6O64_13510 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB G6O64_13515 ENOG4108Z6B deaminase G6O64_13530 ENOG4107WP9 Histidine kinase G6O64_13535 ENOG4108SKK alpha helix protein G6O64_13540 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family G6O64_13550 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) G6O64_13570 ENOG4105FCA ABC transporter periplasmic-binding protein YphF G6O64_13575 ENOG4108F37 ATP-binding component of a transport system G6O64_13580 ENOG4105CNN ABC, transporter G6O64_13585 ENOG4105CPQ Dehydrogenase G6O64_13590 ENOG4108ZKT aldose 1-epimerase G6O64_13595 ENOG4108SB3 DoxX Family G6O64_13625 ENOG4105FUY alpha subunit G6O64_13635 ENOG4105D8G Major Facilitator superfamily G6O64_13640 ENOG4108MN2 Stationary phase inducible protein CsiE G6O64_13645 ENOG4107XM9 (LipO)protein G6O64_13650 ENOG4105ECY inositol monophosphatase G6O64_13670 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins G6O64_13690 ENOG4108ZIT Ferredoxin, 2FE-2S G6O64_13695 ENOG4105WVQ Fe-S assembly protein IscX G6O64_13705 ENOG4105YYA enhanced serine sensitivity protein SseB G6O64_13710 ENOG4105KHC sulfurtransferase G6O64_13715 ENOG4105DN3 alpha-2-macroglobulin domain protein G6O64_13720 ENOG4108JQB penicillin-binding protein 1C G6O64_13750 ENOG4105N21 Membrane G6O64_13765 ENOG4105VPD cellular component movement G6O64_13775 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) G6O64_13785 ENOG41066DY Membrane G6O64_13790 ENOG4108ZMA Outer membrane lipoprotein G6O64_13795 ENOG41062G3 Protein of unknown function (DUF2633) G6O64_13805 ENOG4105BZU Histidine kinase G6O64_13810 ENOG4105C9X ppx gppa phosphatase G6O64_13815 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) G6O64_13820 ENOG4108V3E phosphoribosylglycinamide formyltransferase G6O64_13835 ENOG4105C2W permease G6O64_13840 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) G6O64_13845 ENOG4105K89 arsenate reductase G6O64_13850 ENOG4105ERG peptidase m48, ste24p G6O64_13855 ENOG4105C02 permease G6O64_13865 ENOG410836F Transposase G6O64_13870 ENOG4105TMB Formate nitrite transporter G6O64_13875 ENOG4108JUA Transcriptional regulator G6O64_13880 ENOG4105I6X formate hydrogenlyase maturation G6O64_13885 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit G6O64_13895 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) G6O64_13900 ENOG4108JPZ Monovalent cation H antiporter subunit D G6O64_13905 ENOG4107WQX hydrogenase 4 membrane subunit G6O64_13910 ENOG4105D65 subunit l G6O64_13915 ENOG4105D65 subunit l G6O64_13920 ENOG4107TDF Formate hydrogenlyase subunit 4 G6O64_13925 ENOG4108JPZ Monovalent cation H antiporter subunit D G6O64_13930 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) G6O64_13935 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen G6O64_13940 ENOG4105RH4 Glycine cleavage system transcriptional repressor G6O64_13950 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) G6O64_13960 ENOG4105CGZ zinc metallopeptidase G6O64_13970 ENOG4106KED esterase YpfH G6O64_13985 ENOG4105KUZ arsenate reductase G6O64_13995 ENOG4105BZS acriflavin resistance protein G6O64_14000 ENOG4105BZU Histidine kinase G6O64_14005 ENOG4105BZ8 glutamate synthase G6O64_14015 ENOG4108PVD exported protein G6O64_14020 ENOG4105CV1 Transketolase (EC 2.2.1.1) G6O64_14030 ENOG4105C6K Malic enzyme G6O64_14035 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place G6O64_14040 ENOG4106S4J ethanolamine utilization protein EutP G6O64_14045 ENOG4105NDK ethanolamine utilization protein G6O64_14050 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase G6O64_14055 ENOG4107WUY phosphate acetyltransferase G6O64_14060 ENOG4105KNY Microcompartments protein G6O64_14065 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml G6O64_14070 ENOG4108EKI Dehydrogenase G6O64_14075 ENOG4107RWI ethanolamine utilization protein eutJ G6O64_14080 ENOG4105C0A alcohol dehydrogenase G6O64_14085 ENOG4105ENY Ethanolamine utilization protein eutH G6O64_14090 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase G6O64_14105 ENOG4106D67 ethanolamine utilization protein G6O64_14110 ENOG4108X49 Ethanolamine utilization protein EutK G6O64_14115 ENOG4108K3Z AraC family transcriptional regulator G6O64_14125 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase G6O64_14135 ENOG4105QZU Inner membrane protein YfeZ G6O64_14140 ENOG4105E7K (LipO)protein G6O64_14145 ENOG4105EZR dyp-type peroxidase family protein G6O64_14150 ENOG4107S1E Beta-lactamase G6O64_14155 ENOG4105C5Y PTS System G6O64_14175 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr G6O64_14180 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein G6O64_14185 ENOG4108I5D sulfate abc transporter G6O64_14190 ENOG4105ECW sulfate abc transporter G6O64_14195 ENOG4108IJ6 ABC transporter G6O64_14200 ENOG4105C6T cysteine synthase G6O64_14205 ENOG4105M0Y G6O64_14220 ENOG4105C5Y PTS System G6O64_14225 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) G6O64_14235 ENOG4105C6T cysteine synthase G6O64_14255 ENOG4105VRT cytoplasmic protein G6O64_14260 ENOG4105DHU Bile acid G6O64_14265 ENOG4108M0I Transcriptional regulator G6O64_14300 ENOG4105GXM Putative transcription regulator (DUF1323) G6O64_14305 ENOG4105HZG regulatoR G6O64_14325 ENOG4105D9N nucleoside G6O64_14335 ENOG4109076 Conserved Protein G6O64_14350 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) G6O64_14355 ENOG410863U PTS System G6O64_14365 ENOG4105CN9 Peptidase m42 family protein G6O64_14375 ENOG4108CIP transcriptional regulator G6O64_14380 ENOG4105DY9 regulatoR G6O64_14400 ENOG4105CHM Aminotransferase G6O64_14410 ENOG4105D1S lipid A biosynthesis G6O64_14415 ENOG4105W9M Membrane G6O64_14425 ENOG4108V08 YfdX protein G6O64_14435 ENOG4105CFN oxalyl-CoA decarboxylase G6O64_14440 ENOG4108N2Y auxin Efflux G6O64_14445 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F G6O64_14450 ENOG4105BZU Histidine kinase G6O64_14455 ENOG4108WQH regulatoR G6O64_14460 ENOG4105CW7 secretion protein, HlyD family G6O64_14465 ENOG4105C0R drug resistance transporter emrb qaca subfamily G6O64_14480 ENOG4106NDP Transcriptional regulator G6O64_14490 ENOG4105VNT transposase (IS4 family) protein G6O64_14505 ENOG4105D7K pfkb domain protein G6O64_14530 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) G6O64_14560 ENOG4108V2F protein ybcN in lambdoid DLP12 prophage regi G6O64_14565 ENOG410757E Protein NinE homolog from lambdoid prophage DLP12 G6O64_14570 ENOG4105RWQ Protein of unknown function (DUF1364) G6O64_14585 ENOG4105HRS Antitermination protein G6O64_14600 ENOG4105QFS Lysis protein S homolog from lambdoid prophage G6O64_14605 ENOG4105KUS lysozyme G6O64_14610 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 G6O64_14630 ENOG41064WM Uncharacterized protein YcgX G6O64_14635 ENOG4106YSC G6O64_14640 ENOG4105FKG DNA packaging protein G6O64_14645 ENOG4105UZW Tail fiber assembly protein G6O64_14650 ENOG4107DE1 head-to-tail joining protein G6O64_14660 ENOG4105F7J membrane-bound serine protease G6O64_14670 ENOG4105IM0 capsid protein G6O64_14745 ENOG410685N tail fiber protein G6O64_14750 ENOG4105UZW Tail fiber assembly protein G6O64_14775 ENOG4105DFP Integrase G6O64_14785 ENOG4105S64 Formate nitrite transporter G6O64_14790 ENOG410903C (LipO)protein G6O64_14810 ENOG410836F Transposase G6O64_14815 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation G6O64_14820 ENOG4105KZW UPF0381 protein G6O64_14835 ENOG4108BY2 phosphohistidine phosphatase G6O64_14845 ENOG4106PG1 outer membrane usher protein G6O64_14855 ENOG4105NEV Fimbrial G6O64_14860 ENOG4105UGQ Fimbrial G6O64_14865 ENOG4105US4 fimbrial-like protein yfcP G6O64_14895 ENOG4105EJ9 Membrane G6O64_14900 ENOG4108BPE -transporting atpase G6O64_14905 ENOG4105MH2 YfcL protein G6O64_14915 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) G6O64_14920 ENOG4105F9N Major Facilitator Superfamily G6O64_14925 ENOG4106WZ1 flagella biosynthesis regulator G6O64_14935 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) G6O64_14945 ENOG4105DQR SNARE associated Golgi G6O64_14955 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase G6O64_14960 ENOG4108S3P Sporulation domain protein G6O64_14965 ENOG4105E96 Colicin v production protein G6O64_14970 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase G6O64_14975 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase G6O64_14980 ENOG4105E89 ABC transporter G6O64_14985 ENOG4105E89 ABC transporter G6O64_14990 ENOG4105DSP amino acid AbC transporter G6O64_14995 ENOG4106YG3 ABC transporter G6O64_15000 ENOG4108JEH abc transporter atp-binding protein G6O64_15010 ENOG4105DNE Transposase G6O64_15015 ENOG4105ECP epimerase G6O64_15020 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase G6O64_15025 ENOG4105CYM Glutathione S-transferase G6O64_15030 ENOG4108SHQ Glutathione S-transferase G6O64_15035 ENOG4108RE9 Phosphodiesterase G6O64_15040 ENOG4105PTV Nudix Hydrolase G6O64_15045 ENOG4105CSX c4-dicarboxylate anaerobic carrier G6O64_15050 ENOG4105C6K Malic enzyme G6O64_15055 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) G6O64_15065 ENOG4105XWI UPF0304 protein G6O64_15075 ENOG4107QWE )-transporter G6O64_15085 ENOG4105CHM Aminotransferase G6O64_15090 ENOG4107NQ8 LysR family Transcriptional regulator G6O64_15110 ENOG4105GKE subunit e G6O64_15115 ENOG4107QIZ NADH dehydrogenase G6O64_15120 ENOG4108IEH NADH dehydrogenase subunit g G6O64_15135 ENOG4107UFS subunit j G6O64_15145 ENOG4105D65 subunit l G6O64_15150 ENOG4105C8S subunit m G6O64_15190 ENOG4105TNS Conserved Protein G6O64_15195 ENOG4105E4F Isochorismate synthase G6O64_15210 ENOG4108IPT Naphthoate synthase G6O64_15220 ENOG4105CEY Amp-dependent synthetase and ligase G6O64_15225 ENOG4106GZG polymyxin resistance protein B G6O64_15230 ENOG4105U65 Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity) G6O64_15275 ENOG4108UII YfaZ family G6O64_15280 ENOG4108EWA cinA-like protein G6O64_15285 ENOG4107258 Transcriptional regulator G6O64_15300 ENOG4105CSP Major Facilitator Superfamily G6O64_15310 ENOG4105DNE Transposase G6O64_15315 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) G6O64_15325 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A G6O64_15330 ENOG4105CXY transporter G6O64_15335 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase G6O64_15365 ENOG4105FQR PH-inducible protein involved in stress response G6O64_15370 ENOG4105XPH Ferredoxin G6O64_15375 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) G6O64_15380 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) G6O64_15405 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) G6O64_15410 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) G6O64_15425 ENOG41081SK signal peptide protein G6O64_15430 ENOG4105EDV vault protein G6O64_15435 ENOG4105CHU acetyl-coa acetyltransferase G6O64_15440 ENOG4105CRW Short chain fatty acid transporter G6O64_15445 ENOG4107QNJ CoA-transferase subunit B G6O64_15450 ENOG4107QP7 CoA-transferase subunit A G6O64_15455 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family G6O64_15460 ENOG4105BZU Histidine kinase G6O64_15465 ENOG4105BZU Histidine kinase G6O64_15470 ENOG41068CG regulatoR G6O64_15475 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC G6O64_15485 ENOG4105FCK Membrane G6O64_15490 ENOG4105CJ2 (LipO)protein G6O64_15495 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) G6O64_15500 ENOG4105CF1 Alkylated DNA repair protein G6O64_15505 ENOG4105IBP Cyclic peptide transporter G6O64_15520 ENOG4108ZNS ferredoxin-type protein NapF G6O64_15525 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase G6O64_15535 ENOG4108BGM Quinol dehydrogenase periplasmic component G6O64_15540 ENOG4105GXZ Ferredoxin-type protein NapH G6O64_15545 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) G6O64_15550 ENOG4105CUW cytochrome C-TYPE protein G6O64_15560 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) G6O64_15565 ENOG41060IM Heme exporter protein G6O64_15570 ENOG4105X3C heme exporter protein G6O64_15580 ENOG4105DA4 cytochrome c-type biogenesis protein G6O64_15585 ENOG4107QX9 Thiol disulfide interChange protein G6O64_15590 ENOG4105KWW Biogenesis protein G6O64_15595 ENOG4105WH1 Two component transcriptional regulator luxr family G6O64_15635 ENOG4105E68 Sulfatase G6O64_15655 ENOG4105CFI type iii restriction protein res subunit G6O64_15660 ENOG4105I08 Pseudouridine synthase G6O64_15670 ENOG4105HG6 G6O64_15675 ENOG4108JQ5 ABC transporter G6O64_15680 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component G6O64_15685 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component G6O64_15690 ENOG4105E43 Extracellular solute-binding protein, family 5 G6O64_15695 ENOG4105CXC rtn protein G6O64_15700 ENOG4107TT5 NLP P60 protein G6O64_15705 ENOG41076MN Phosphoesterase, PA-phosphatase related G6O64_15710 ENOG4105CKI cobalamin synthesis protein G6O64_15715 ENOG4105DEI Mannitol dehydrogenase G6O64_15725 ENOG4105KRS Proteinase inhibitor G6O64_15730 ENOG4105S8Q sugar efflux transporter G6O64_15735 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein G6O64_15740 ENOG4105DE4 1-phosphofructokinase G6O64_15745 ENOG4105DM4 PTS System G6O64_15755 ENOG4105DD7 kinase (PfkB family G6O64_15760 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) G6O64_15765 ENOG4105D9N nucleoside G6O64_15770 ENOG4108Y4K DNA-binding transcriptional activator G6O64_15780 ENOG4105D9N nucleoside G6O64_15785 ENOG4105DD7 kinase (PfkB family G6O64_15795 ENOG4105HMI Membrane G6O64_15800 ENOG4105DUM transcriptional regulator, lysR family G6O64_15805 ENOG4108IQI permease G6O64_15810 ENOG4105D05 Receptor G6O64_15825 ENOG4105DHF Membrane G6O64_15835 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator G6O64_15840 ENOG4105C2J ABC transporter G6O64_15845 ENOG4108HWV )-transporter G6O64_15850 ENOG4107SJI Dehydrogenase G6O64_15860 ENOG4105Y9N Membrane G6O64_15865 ENOG4107GZ4 SanA protein G6O64_15875 ENOG41067MG lrgb family G6O64_15885 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) G6O64_15895 ENOG4105ETP RND efflux system, outer membrane lipoprotein G6O64_15900 ENOG4105H9W Short-chain dehydrogenase reductase Sdr G6O64_15905 ENOG4105KHU inner membrane protein YohD G6O64_15910 ENOG41069YE inner membrane protein yohC G6O64_15915 ENOG41061WM D-Alanyl-D-Alanine G6O64_15920 ENOG4105CXG d-lactate dehydrogenase G6O64_15925 ENOG4107QK4 glycoside hydrolase, family 3 domain protein G6O64_15930 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system G6O64_15935 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component G6O64_15940 ENOG4108IJ8 ABC transporter G6O64_15945 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component G6O64_15955 ENOG4108XDN Transcriptional regulator G6O64_15985 ENOG4108WF3 methyltransferase G6O64_16005 ENOG4106FE3 DNA repair G6O64_16010 ENOG4108HRK Histidine kinase G6O64_16015 ENOG4108NEV two component transcriptional regulator, LytTR family G6O64_16020 ENOG4108W15 Protein of unknown function (DUF1456) G6O64_16025 ENOG4108YCW (LipO)protein G6O64_16030 ENOG410903U zinc ion binding G6O64_16035 ENOG4105DEG Vwa containing coxe family protein G6O64_16060 ENOG4105D1F ATP-binding protein G6O64_16065 ENOG41067AK Protein of unknown function (DUF2574) G6O64_16070 ENOG41063W2 Fimbrial protein G6O64_16075 ENOG4108MQF Chaperone G6O64_16095 ENOG410662B Type-1 fimbrial protein G6O64_16100 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly G6O64_16120 ENOG4105DWF phosphomethylpyrimidine kinase G6O64_16125 ENOG4108UQ1 hydrolase, family 25 G6O64_16130 ENOG4105FDP GntR family transcriptional regulator G6O64_16135 ENOG4108TFM Kinase, PfkB family G6O64_16140 ENOG4108KD5 ADP-ribosylation crystallin J1 G6O64_16145 ENOG4105EAA nucleoside G6O64_16150 ENOG4105EIE fructose-bisphosphate aldolase G6O64_16165 ENOG41082GB PTS system galactitol-specific transporter subunit IIA G6O64_16180 ENOG41090UW PTS System G6O64_16185 ENOG4105DT3 PTS system, galactitol-specific IIc component G6O64_16190 ENOG4107WTH Galactitol-1-phosphate dehydrogenase G6O64_16205 ENOG41076Z6 Uncharacterized protein yegR G6O64_16210 ENOG4105CFP Peptidase U32 G6O64_16215 ENOG4105KWI UPF0339 protein G6O64_16225 ENOG4105E3W Two component transcriptional regulator (Winged helix family G6O64_16230 ENOG4105EB3 Histidine kinase G6O64_16270 ENOG4108M24 von Willebrand factor, type A G6O64_16275 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase G6O64_16280 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding G6O64_16285 ENOG4105R8A Heat shock protein G6O64_16290 ENOG4105D03 DNA-3-methyladenine glycosylase II G6O64_16295 ENOG4105BZU Histidine kinase G6O64_16300 ENOG4105DBI uridine monophosphokinase G6O64_16310 ENOG4108GAE asmA family G6O64_16315 ENOG4105EE5 Membrane protein terC G6O64_16325 ENOG4105DAY polysaccharide export protein G6O64_16330 ENOG4105KJF protein tyrosine phosphatase G6O64_16335 ENOG4105D75 Capsular exopolysaccharide family G6O64_16340 ENOG41090RK glycosyl transferase G6O64_16345 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB G6O64_16350 ENOG4107RXY Glycosyl transferase G6O64_16355 ENOG4108NYJ Colanic acid G6O64_16360 ENOG4105ECJ Glycosyl Transferase G6O64_16365 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF G6O64_16370 ENOG4105C0K Gdp-mannose 4,6-dehydratase G6O64_16375 ENOG4105C30 Nad-dependent epimerase dehydratase G6O64_16380 ENOG4105FGF GDP-mannose mannosyl hydrolase G6O64_16385 ENOG4106CD9 glycosyl transferase group 1 G6O64_16390 ENOG4105CJT Mannose-1-phosphate guanylyltransferase G6O64_16395 ENOG4107QKV phosphomannomutase G6O64_16400 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) G6O64_16405 ENOG4105C6Y Udp-glucose 6-dehydrogenase G6O64_16430 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) G6O64_16435 ENOG4105ECC imidazole-glycerol-phosphate dehydratase G6O64_16460 ENOG4105VTW prevent-host-death family G6O64_16465 ENOG4105KRQ Addiction module toxin, Txe YoeB family G6O64_16470 ENOG4107SRH Nad-dependent epimerase dehydratase G6O64_16475 ENOG4105EQ1 Transcriptional regulator G6O64_16485 ENOG4105CUB amino acid G6O64_16490 ENOG4105CUC YeeE YedE family protein G6O64_16500 ENOG4105CJB Exodeoxyribonuclease I G6O64_16505 ENOG4105DZ1 carboxypeptidase G6O64_16515 ENOG4105DR8 Membrane G6O64_16525 ENOG4105KTW ethanolamine utilization protein G6O64_16530 ENOG4105M3W utilization protein G6O64_16545 ENOG4105C0A alcohol dehydrogenase G6O64_16560 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml G6O64_16570 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) G6O64_16575 ENOG4105KNY Microcompartments protein G6O64_16580 ENOG4105KNY Microcompartments protein G6O64_16590 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit G6O64_16595 ENOG4108ZFT Dehydratase small subunit G6O64_16600 ENOG4105YCI dehydratase medium subunit G6O64_16605 ENOG4105DMB glycerol dehydratase G6O64_16610 ENOG4105EHR propanediol utilization protein pduB G6O64_16615 ENOG4105KNY Microcompartments protein G6O64_16620 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) G6O64_16630 ENOG4108P62 biosynthesis protein (CbiG) G6O64_16635 ENOG4108YZT Adenosylcobinamide kinase G6O64_16660 ENOG4106P55 Transcriptional regulator G6O64_16670 ENOG4105CSH Transporter G6O64_16675 ENOG4105FYV Amp nucleosidase G6O64_16690 ENOG4105UQX Mate efflux family protein G6O64_16700 ENOG4107R11 Transcriptional regulator G6O64_16760 ENOG4108MEK Metal-binding protein YodA G6O64_16775 ENOG4105VT2 5-hydroxyisourate hydrolase G6O64_16780 ENOG4105CK6 Two component transcriptional regulator (Winged helix family G6O64_16785 ENOG4107ZY3 Histidine kinase G6O64_16815 ENOG4105FCK Membrane G6O64_16820 ENOG4105Y0K Inner membrane protein YedR G6O64_16825 ENOG4105EST Metal Dependent Phosphohydrolase G6O64_16830 ENOG4105DVF Cytosine-specific methyltransferase G6O64_16835 ENOG41090BB DNA mismatch endonuclease (vsr) G6O64_16845 ENOG4105CKW Inner membrane protein yedI G6O64_16850 ENOG4105VNZ cytoplasmic protein G6O64_16865 ENOG4105YX3 cellular response to acidity G6O64_16875 ENOG4107TKS colanic acid capsular biosynthesis activation protein A G6O64_16880 ENOG4105D19 Role in flagellar biosynthesis (By similarity) G6O64_16890 ENOG4105CN7 Flagellar biosynthetic protein FliP G6O64_16895 ENOG4105K0P flagellar biosynthesis protein G6O64_16900 ENOG4105DD5 Flagellar motor switch protein G6O64_16905 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) G6O64_16910 ENOG4107ZI8 flagellar basal body-associated protein flil G6O64_16915 ENOG4105WF4 Flagellar hook-length control protein G6O64_16920 ENOG4105GSA Flagellar export protein flij G6O64_16925 ENOG4108JIR Flagellum-specific ATP synthase G6O64_16930 ENOG41090PJ Flagellar assembly protein G6O64_16935 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) G6O64_16940 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) G6O64_16945 ENOG4105VQ0 flagellar hook-basal body complex protein fliE G6O64_16950 ENOG410814C multidrug resistance protein G6O64_16955 ENOG4108V1U phospholipid-binding protein G6O64_16960 ENOG4108UQN AraC family transcriptional regulator G6O64_16980 ENOG4105D7V transposase G6O64_16985 ENOG4108RAV Conserved protein G6O64_16995 ENOG41066VF YeeE YedE family protein G6O64_17000 ENOG4108W9D (LipO)protein G6O64_17005 ENOG4105E5K Alpha-amylase G6O64_17015 ENOG4105MQ3 flagellar protein FliS G6O64_17035 ENOG4105C3G gtp-binding protein G6O64_17045 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria G6O64_17050 ENOG4105CHH sulfate transporter G6O64_17055 ENOG4105C5T Phosphoribosyl pyrophosphate synthase G6O64_17080 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) G6O64_17085 ENOG4108YY7 Invasion gene expression up-regulator SirB G6O64_17115 ENOG4105EWV Sodium calcium exchanger membrane region G6O64_17120 ENOG4105WS7 Cation transport regulator G6O64_17125 ENOG4108NH8 Cation transport protein G6O64_17130 ENOG41090EX DsrE family G6O64_17135 ENOG4105ID0 Putative invasin G6O64_17140 ENOG4105WH1 Two component transcriptional regulator luxr family G6O64_17145 ENOG4105BZU Histidine kinase G6O64_17150 ENOG4105DQQ Major facilitator superfamily MFS_1 G6O64_17155 ENOG4105CRU nitrate reductase, alpha subunit G6O64_17160 ENOG4108IUE nitrate reductase beta subunit G6O64_17165 ENOG4105R3A Nitrate reductase G6O64_17170 ENOG41076YT nitrate reductase, gamma subunit G6O64_17185 ENOG4105CIY formyltetrahydrofolate deformylase G6O64_17190 ENOG4105K5B UPF0225 protein G6O64_17195 ENOG4105D78 K07001 NTE family protein G6O64_17200 ENOG4105I93 response regulator G6O64_17205 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase G6O64_17210 ENOG4108SAU DNA-binding protein H-ns G6O64_17215 ENOG4107104 thymidine kinase G6O64_17220 ENOG4105VNT transposase (IS4 family) protein G6O64_17225 ENOG4105C0A alcohol dehydrogenase G6O64_17230 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein G6O64_17235 ENOG4108J59 Extracellular solute-binding protein, family 5 G6O64_17240 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component G6O64_17245 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component G6O64_17250 ENOG4105C3U ABC transporter G6O64_17255 ENOG4108JQ7 (ABC) transporter G6O64_17275 ENOG4107SVH Potassium channel protein G6O64_17285 ENOG4105K9H YciI-like protein G6O64_17290 ENOG4108C33 Resolvase G6O64_17375 ENOG410822N TonB family G6O64_17380 ENOG4105NAU thioesterase Superfamily protein G6O64_17400 ENOG4105EIF outer membrane protein W G6O64_17405 ENOG4108I1J Integrase G6O64_17420 ENOG4106G8A Qin prophage G6O64_17435 ENOG4107712 G6O64_17445 ENOG41087BU transcriptional repressor DicA G6O64_17525 ENOG4108MXB Protein of unknown function (DUF968) G6O64_17530 ENOG4105KSK (crossover) junction endodeoxyribonuclease G6O64_17535 ENOG4105HGD Antitermination protein G6O64_17575 ENOG4105QFS Lysis protein S homolog from lambdoid prophage G6O64_17600 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 G6O64_17610 ENOG4105UZW Tail fiber assembly protein G6O64_17635 ENOG4105IM0 capsid protein G6O64_17710 ENOG4108X9F tail fiber protein G6O64_17715 ENOG4105UZW Tail fiber assembly protein G6O64_17720 ENOG4108WF3 methyltransferase G6O64_17795 ENOG4108MXB Protein of unknown function (DUF968) G6O64_17800 ENOG4105KSK (crossover) junction endodeoxyribonuclease G6O64_17805 ENOG4105HGD Antitermination protein G6O64_17845 ENOG4105QFS Lysis protein S homolog from lambdoid prophage G6O64_17870 ENOG4105UZW Tail fiber assembly protein G6O64_17885 ENOG4108C33 Resolvase G6O64_17895 ENOG4108WF3 methyltransferase G6O64_17940 ENOG4105DK0 Indole-3-glycerol phosphate synthase G6O64_17945 ENOG4108EFP Anthranilate synthase component II G6O64_17950 ENOG4105CRQ synthase (Component I) G6O64_17960 ENOG4105DB7 PHP domain protein G6O64_17965 ENOG4107RTD sua5 ycio yrdc ywlc family protein G6O64_17975 ENOG4105FE9 pseudouridine synthase G6O64_17980 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase G6O64_17985 ENOG4105UBK short-chain dehydrogenase reductase G6O64_17990 ENOG4105ERU peptidase G6O64_17995 ENOG4105RKX Protein of unknown function (DUF2498) G6O64_18000 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) G6O64_18005 ENOG4107R11 Transcriptional regulator G6O64_18030 ENOG4107QM5 aconitate hydratase G6O64_18045 ENOG4105Q4A inner membrane protein yciS G6O64_18050 ENOG4105CFV Tetratricopeptide repeat protein G6O64_18060 ENOG4108ZJT translation initiation factor, Sui1 G6O64_18070 ENOG4105N2W Transcriptional regulator G6O64_18075 ENOG410643D UPF0509 protein G6O64_18100 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH G6O64_18105 ENOG4105WDY DNA (cytosine-5-)-methyltransferase G6O64_18110 ENOG4108JQ2 peptide transport system atp-binding protein G6O64_18115 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein G6O64_18120 ENOG4108EU3 peptide transport system, permease G6O64_18125 ENOG4108I5W peptide transport system, permease protein G6O64_18130 ENOG4108HIY periplasmic G6O64_18135 ENOG4105N0E Protein of unknown function (DUF2543) G6O64_18140 ENOG4105CUB amino acid G6O64_18150 ENOG4105CFQ glutamine synthetase G6O64_18155 ENOG4108Z86 Glutamine amidotransferase G6O64_18160 ENOG4107VRI Transcriptional regulator G6O64_18170 ENOG4105CJP fad dependent oxidoreductase G6O64_18180 ENOG4105E51 psp operon transcriptional activator G6O64_18185 ENOG41087YS Phage shock protein A G6O64_18190 ENOG4105YYT phage shock protein B G6O64_18195 ENOG4105FM1 phage shock protein C G6O64_18200 ENOG4105NNG Peripheral inner membrane phage-shock protein G6O64_18205 ENOG4105K8Z Phage shock protein G6O64_18215 ENOG4105WEM extracellular solute-binding protein G6O64_18220 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component G6O64_18230 ENOG4107RRD Dehydrogenase G6O64_18235 ENOG4107TYA transient receptor potential locus G6O64_18240 ENOG4105CK5 oxidoreductase G6O64_18245 ENOG4105C71 hydrolase family 65, central catalytic G6O64_18250 ENOG4107URF beta-phospho-glucomutase G6O64_18270 ENOG4105FKQ transcriptional regulator G6O64_18275 ENOG4105CM6 amino acid regulated cytosolic protein G6O64_18290 ENOG4108JU8 Transcriptional regulator G6O64_18295 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) G6O64_18300 ENOG4107S8C mandelate racemase muconate lactonizing G6O64_18305 ENOG4105KXI murein peptide amidase A G6O64_18335 ENOG4105ENX hydrolase G6O64_18340 ENOG4105EQ2 LysR family Transcriptional regulator G6O64_18345 ENOG4107QSI ABC, transporter G6O64_18365 ENOG4105S5I Membrane G6O64_18370 ENOG4105Q9Y Universal stress protein G6O64_18375 ENOG4105DS0 Transcriptional regulator, Crp Fnr family G6O64_18380 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) G6O64_18400 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B G6O64_18405 ENOG4105CH2 amidohydrolase G6O64_18410 ENOG4106KR7 LysR family Transcriptional regulator G6O64_18415 ENOG4108DG9 Smr protein MutS2 G6O64_18420 ENOG4105BZU Histidine kinase G6O64_18430 ENOG4105C1J atp-dependent rna helicase G6O64_18480 ENOG4105WI6 cell killing protein encoded within cryptic prophage G6O64_18500 ENOG4105RWQ Protein of unknown function (DUF1364) G6O64_18610 ENOG4105CC5 ABC transporter G6O64_18615 ENOG4105CC5 ABC transporter G6O64_18620 ENOG4105DIK (ABC) transporter G6O64_18630 ENOG4108RW8 Universal stress protein F G6O64_18635 ENOG4105FCK Membrane G6O64_18640 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) G6O64_18645 ENOG4105IKK cytoplasmic protein G6O64_18650 ENOG41090X5 Heat shock protein hslJ G6O64_18655 ENOG4105C5I Dehydrogenase G6O64_18660 ENOG4107H52 Dicarboxylate transport G6O64_18665 ENOG410689M (LipO)protein G6O64_18670 ENOG4105WXT Conserved Protein G6O64_18675 ENOG4108WFR AraC Family Transcriptional Regulator G6O64_18695 ENOG4108HPI phosphatidate Cytidylyltransferase G6O64_18700 ENOG4108HPI phosphatidate Cytidylyltransferase G6O64_18705 ENOG4105E8V Alpha Beta Hydrolase Fold protein G6O64_18710 ENOG41077RS Phosphatase G6O64_18720 ENOG4105CQ7 ATP-dependent helicase G6O64_18725 ENOG4107DB1 DUF218 domain G6O64_18755 ENOG4105C26 Dehydrogenase G6O64_18770 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase G6O64_18775 ENOG4105CPW cytochrome b561 G6O64_18780 ENOG4105UPP uncharacterized protein ydcA G6O64_18785 ENOG4107NK6 Hok/gef family G6O64_18790 ENOG4105C8Q Methyl-accepting chemotaxis G6O64_18795 ENOG4105DDW LysR family Transcriptional regulator G6O64_18800 ENOG4105E32 cytoplasmic protein G6O64_18810 ENOG4105Z2P Protein of unknown function (DUF465) G6O64_18815 ENOG4108Z9I -acetyltransferase G6O64_18820 ENOG4107WE3 acetyltransferase YdcK G6O64_18825 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein G6O64_18830 ENOG41088CC tellurite resistance protein tehB G6O64_18850 ENOG4105D7V transposase G6O64_18880 ENOG4108JCI Transcriptional regulator G6O64_18885 ENOG4105CFP Peptidase U32 G6O64_18890 ENOG4105RR0 Protein of unknown function (DUF2554) G6O64_18905 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin G6O64_18910 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family G6O64_18915 ENOG4107TYH extracellular solute-binding protein family 1 G6O64_18920 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) G6O64_18930 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component G6O64_18955 ENOG410654E Membrane G6O64_18960 ENOG4105R71 cytoplasmic protein G6O64_18965 ENOG4108T9Y Inner membrane protein ydcZ G6O64_18970 ENOG4108Z7F N-acetyltransferase G6O64_19000 ENOG4105CHB tonB-dependent Receptor G6O64_19005 ENOG4108NS2 receptor G6O64_19010 ENOG4105C85 amino acid G6O64_19015 ENOG4108N27 Glutathione S-transferase G6O64_19025 ENOG4105CS6 Rhs element vgr protein G6O64_19085 ENOG410600T transposase G6O64_19100 ENOG4108MEJ flavin reductase domain protein G6O64_19105 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase G6O64_19110 ENOG4105JAB phenazine biosynthesis protein, phzf family G6O64_19115 ENOG4105D0D Nitrate reductase 2, gamma subunit G6O64_19120 ENOG4108NZN Respiratory nitrate reductase 2 delta chain G6O64_19125 ENOG4108IUE nitrate reductase beta subunit G6O64_19130 ENOG4105CRU nitrate reductase, alpha subunit G6O64_19150 ENOG4108UI3 Leucine Rich repeat G6O64_19175 ENOG4105RPH Inner membrane protein YddG G6O64_19185 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein G6O64_19190 ENOG4108MG3 formate dehydrogenase G6O64_19195 ENOG41084S7 Plasmid maintenance system antidote protein G6O64_19210 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein G6O64_19215 ENOG4105TPS biofilm-dependent modulation protein G6O64_19225 ENOG4108Z9K Osmotically inducible protein G6O64_19230 ENOG4107H6U ABC transporter G6O64_19235 ENOG4105C3U ABC transporter G6O64_19240 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component G6O64_19245 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component G6O64_19250 ENOG4105DEF Extracellular solute-binding protein, family 5 G6O64_19255 ENOG4108UQS dipeptidase G6O64_19260 ENOG4105BZU Histidine kinase G6O64_19270 ENOG4105F32 YngK protein G6O64_19275 ENOG4105E5D amino acid G6O64_19280 ENOG4105CVK Glutamate decarboxylase G6O64_19285 ENOG4107RAN Peptidase, M16 G6O64_19290 ENOG4105PE1 Receptor G6O64_19295 ENOG4105VNT transposase (IS4 family) protein G6O64_19300 ENOG4105CQ0 ABC transporter G6O64_19310 ENOG4105C4X radical SAM domain protein G6O64_19315 ENOG4105ENH Sulfatase G6O64_19320 ENOG4105Z68 AraC Family Transcriptional Regulator G6O64_19330 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit G6O64_19335 ENOG4106PIH fimbrial-like protein ydeQ G6O64_19385 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein G6O64_19430 ENOG4105BZU Histidine kinase G6O64_19450 ENOG4105CSV Glutaminase G6O64_19455 ENOG4105C26 Dehydrogenase G6O64_19460 ENOG4105EGI Transcriptional regulator G6O64_19480 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes G6O64_19485 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF G6O64_19490 ENOG4106DNR multiple antibiotic resistance protein G6O64_19495 ENOG4105CS2 ec 3.2.1.21 G6O64_19505 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria G6O64_19510 ENOG4108YDI single-species biofilm formation on inanimate substrate G6O64_19515 ENOG4108WTK competence damage-inducible protein G6O64_19520 ENOG4105DGW oligopeptidase A G6O64_19525 ENOG4105EMU Dehydrogenase G6O64_19530 ENOG4107XBN GntR Family Transcriptional Regulator G6O64_19535 ENOG41061EV selenium-binding protein YdfZ G6O64_19540 ENOG4105DEI Mannitol dehydrogenase G6O64_19575 ENOG4105JBR DNA replication protein G6O64_19630 ENOG4105QAX Iron-sulfur G6O64_19635 ENOG4107KGK dmso reductase anchor subunit G6O64_19640 ENOG4108NEM leader-binding protein dmsD G6O64_19650 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) G6O64_19655 ENOG4105DAG ROK family G6O64_19660 ENOG4106NZI LysR family Transcriptional regulator G6O64_19665 ENOG4105D94 Major Facilitator Superfamily G6O64_19700 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap G6O64_19715 ENOG4105DSF transport protein G6O64_19720 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) G6O64_19725 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) G6O64_19730 ENOG4105C5D exported protein G6O64_19735 ENOG4105D5Q Arginine ornithine antiporter G6O64_19745 ENOG4105RA2 Membrane G6O64_19750 ENOG4107EXC regulatoR G6O64_19755 ENOG4105JJR Histidine kinase G6O64_19765 ENOG4105C9Q fumarate hydratase class II G6O64_19770 ENOG4107GFK fumarate G6O64_19775 ENOG4105EIP mannose-6-phosphate isomerase G6O64_19780 ENOG4106J39 exported protein G6O64_19785 ENOG4108QNI outer membrane porin protein G6O64_19790 ENOG4105CT4 transporter G6O64_19795 ENOG4105CNT hydrolase family 2 G6O64_19800 ENOG4105XEA Tetr family transcriptional regulator G6O64_19805 ENOG4107ZQV short-chain dehydrogenase reductase G6O64_19815 ENOG4107P2S Transcriptional regulator G6O64_19820 ENOG4105CI1 PTS System G6O64_19825 ENOG4105C87 Aminotransferase class I and II G6O64_19835 ENOG4105D9R oxidoreductase G6O64_19840 ENOG4106C6R beta-lactam resistance protein G6O64_19845 ENOG4105QZ5 OriC-binding nucleoid-associated protein G6O64_19855 ENOG4106C6R beta-lactam resistance protein G6O64_19860 ENOG4105QZ5 OriC-binding nucleoid-associated protein G6O64_19870 ENOG4106C6R beta-lactam resistance protein G6O64_19875 ENOG4105QZ5 OriC-binding nucleoid-associated protein G6O64_19885 ENOG4106C6R beta-lactam resistance protein G6O64_19890 ENOG4105QZ5 OriC-binding nucleoid-associated protein G6O64_19895 ENOG4105M9B inner membrane protein ydgK G6O64_19920 ENOG4108UQQ Electron transport complex G6O64_19930 ENOG4105CSM endonuclease III G6O64_19935 ENOG4105DUX Transporter G6O64_19945 ENOG4105VNT transposase (IS4 family) protein G6O64_19970 ENOG410642K Lysozyme inhibitor G6O64_19980 ENOG4108XTF Outer Membrane Lipoprotein G6O64_19995 ENOG4105Y49 secretion protein, HlyD family G6O64_20000 ENOG4105DSW Fusaric acid resistance protein G6O64_20005 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) G6O64_20010 ENOG4107RGM aldo keto reductase G6O64_20015 ENOG4105XZD Fe-S protein G6O64_20020 ENOG4108WUH Transcriptional regulator, TetR family G6O64_20025 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase G6O64_20030 ENOG4108UYE Lactoylglutathione lyase G6O64_20045 ENOG4105M2J Glutaredoxin G6O64_20055 ENOG4105K4H Nlp p60 protein G6O64_20060 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) G6O64_20065 ENOG4105F27 Major Facilitator G6O64_20080 ENOG4105F52 Transcriptional regulator G6O64_20085 ENOG4105CZQ inner membrane transport protein YdhC G6O64_20090 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase G6O64_20095 ENOG4108R6K riboflavin synthase, subunit alpha G6O64_20120 ENOG4105N0V mono-oxygenase ydhR G6O64_20125 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain G6O64_20130 ENOG4108Y7C Conserved Protein G6O64_20135 ENOG4108NWD Cytochrome G6O64_20140 ENOG4108393 oxidoreductase Fe-S subunit G6O64_20145 ENOG4105JVW G6O64_20150 ENOG4105WE2 aldehyde ferredoxin oxidoreductase G6O64_20155 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein G6O64_20160 ENOG4105RFR Protein of unknown function (DUF2767) G6O64_20165 ENOG4105CA9 Pyruvate kinase G6O64_20170 ENOG4105KMX major outer membrane lipoprotein G6O64_20175 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein G6O64_20190 ENOG4105JRK feS assembly protein SufD G6O64_20195 ENOG4105C3K feS assembly ATPase SufC G6O64_20200 ENOG4105DIW FeS assembly protein SUFB G6O64_20205 ENOG4108Z4V iron-sulfur cluster assembly G6O64_20210 ENOG410671Z uncharacterized protein ydiH G6O64_20215 ENOG4105KA0 thioesterase Superfamily protein G6O64_20220 ENOG4105CQB FAD linked oxidase domain protein G6O64_20225 ENOG4105IPI Membrane G6O64_20240 ENOG4105SUA Ydil protein G6O64_20260 ENOG4105EMV Major Facilitator G6O64_20290 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) G6O64_20300 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) G6O64_20315 ENOG4108TC0 Diguanylate phosphodiesterase G6O64_20325 ENOG4108QBX (LipO)protein G6O64_20335 ENOG4108V06 Glutathione peroxidase G6O64_20370 ENOG41082NX 50s ribosomal protein l35 G6O64_20375 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) G6O64_20405 ENOG4108NE3 Salt-induced outer membrane protein G6O64_20410 ENOG4105DE4 1-phosphofructokinase G6O64_20415 ENOG4105P10 Uncharacterized protein ydiZ G6O64_20425 ENOG4107PN8 YfeABCD locus regulator G6O64_20430 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 G6O64_20435 ENOG4107K5X Membrane-bound metal-dependent hydrolase G6O64_20440 ENOG4108ETY sodium dicarboxylate symporter G6O64_20455 ENOG4105CH6 catalase G6O64_20465 ENOG4105F8D glycoside hydrolase family 4 G6O64_20470 ENOG4105EZV Transcriptional regulator G6O64_20475 ENOG4105VCP PTS System G6O64_20480 ENOG4105CK1 PTS System G6O64_20485 ENOG4105VZJ PTS System G6O64_20490 ENOG4105KKI DNA-binding transcriptional activator OsmE G6O64_20500 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) G6O64_20515 ENOG4108SPG Periplasmic Protein G6O64_20545 ENOG4105CGK Exodeoxyribonuclease III G6O64_20550 ENOG4108RSN SNARE associated Golgi G6O64_20555 ENOG4108KCW iron-sulfur cluster binding G6O64_20560 ENOG4108N5C SNARE associated Golgi protein-related protein G6O64_20565 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) G6O64_20570 ENOG4105VNH ABC transporter solute-binding protein G6O64_20575 ENOG4105CXZ ABC transporter, permease G6O64_20585 ENOG4105CXZ ABC transporter, permease G6O64_20590 ENOG4108VGW abc transporter atp-binding protein G6O64_20595 ENOG4107RM6 sulfurtransferase G6O64_20615 ENOG4105M6F mutator MutT protein G6O64_20620 ENOG4105MTM Protein of unknown function (DUF1496) G6O64_20625 ENOG4105D82 Glutamate dehydrogenase G6O64_20640 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) G6O64_20650 ENOG41069NU Nitroreductase G6O64_20655 ENOG4105D07 Signal peptide peptidase, SppA G6O64_20660 ENOG4105HDK L-asparaginase G6O64_20665 ENOG4108RWI nicotinamidase G6O64_20670 ENOG4105VUT cytoplasmic protein G6O64_20680 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase G6O64_20685 ENOG4105VNT transposase (IS4 family) protein G6O64_20690 ENOG4105DSB aldose 1-epimerase G6O64_20695 ENOG4105CV8 reductase G6O64_20700 ENOG4105GNX MltA-interacting MipA family protein G6O64_20705 ENOG4105CYN Serine protein kinase G6O64_20715 ENOG4106KTS Inner membrane protein yeaI G6O64_20725 ENOG4108KHP Diguanylate cyclase G6O64_20730 ENOG4108KXH Ybak prolyl-tRNA synthetase associated G6O64_20745 ENOG4105R1U AraC Family Transcriptional Regulator G6O64_20750 ENOG4105DJ2 Major Facilitator Superfamily G6O64_20755 ENOG4105K78 MarR family Transcriptional regulator G6O64_20760 ENOG4105UCG Domain of unknown function (DUF333) G6O64_20765 ENOG410620I Diguanylate cyclase G6O64_20770 ENOG4106G4W G6O64_20780 ENOG4105Y3U Transglycosylase-associated protein G6O64_20785 ENOG4105YP6 Domain of unknown function (DUF1869) G6O64_20790 ENOG4108YS1 cytoplasmic protein G6O64_20800 ENOG4105EJC lysr family transcriptional regulator G6O64_20805 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) G6O64_20810 ENOG4105C94 Transporter G6O64_20815 ENOG4105DVW rieske (2Fe-2S) G6O64_20820 ENOG4105E3J oxidoreductase G6O64_20825 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) G6O64_20830 ENOG4105CEY Amp-dependent synthetase and ligase G6O64_20835 ENOG4105Y4Z Outer Membrane Lipoprotein G6O64_20840 ENOG41072GX Peptidase M22 Glycoprotease G6O64_20845 ENOG4105DVT helicase G6O64_20850 ENOG4105M4H endoribonuclease L-psp G6O64_20860 ENOG4105V2F Uncharacterized protein yoac G6O64_20870 ENOG4105CRQ synthase (Component I) G6O64_20880 ENOG4105EJQ L-serine dehydratase G6O64_20885 ENOG4107XTP (EAL) domain protein G6O64_20890 ENOG4105EE5 Membrane protein terC G6O64_20895 ENOG4105DAS pts system G6O64_20900 ENOG4105ETZ PTS System G6O64_20905 ENOG4105F3R pts system mannose fructose sorbose family iid G6O64_20920 ENOG4105DHI Methyltransferase G6O64_20935 ENOG4105Q3Y exported protein G6O64_20945 ENOG4105TIK G6O64_20950 ENOG4105J4Q Transcriptional regulator G6O64_20965 ENOG4105CN1 protease G6O64_20975 ENOG4108ZGC gaf domain protein G6O64_20980 ENOG4105H2K paraquat-inducible protein a G6O64_20985 ENOG4105DY2 Paraquat-inducible protein b G6O64_21010 ENOG4105UVW uncharacterized protein yebW G6O64_21045 ENOG4108QHK Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway G6O64_21055 ENOG4105QYW Excisionase-like protein from lambdoid prophage 14 G6O64_21075 ENOG4108I1J Integrase G6O64_21080 ENOG4105NKT exported protein G6O64_21085 ENOG4108PNC copper resistance G6O64_21090 ENOG4105FXM Copper resistance protein G6O64_21095 ENOG4105MPK DNA polymerase III subunit theta G6O64_21100 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase G6O64_21105 ENOG4105UMD exodeoxyribonuclease X G6O64_21110 ENOG4105CUG Oligopeptidase b G6O64_21115 ENOG4108Q2J Inner membrane protein YebE G6O64_21125 ENOG4105X2V dna damage-inducible protein G6O64_21130 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR G6O64_21135 ENOG4108UHU Aldolase G6O64_21140 ENOG4105C01 Dihydroxy-acid dehydratase G6O64_21145 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase G6O64_21150 ENOG4106KNT transcriptional regulator G6O64_21155 ENOG4105CA9 Pyruvate kinase G6O64_21195 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase G6O64_21200 ENOG4105DR5 peptidase G6O64_21205 ENOG4105NXV High-affinity zinc uptake system protein G6O64_21215 ENOG4105FAV ABC, transporter G6O64_21235 ENOG4107S01 Repressor protein MetJ G6O64_21245 ENOG4105CDY transcriptional regulatory protein G6O64_21250 ENOG4108TIT dATP pyrophosphohydrolase G6O64_21260 ENOG4105D3W isochorismatase G6O64_21265 ENOG4106FE3 DNA repair G6O64_21320 ENOG4105KSK (crossover) junction endodeoxyribonuclease G6O64_21325 ENOG4105HGD Antitermination protein G6O64_21395 ENOG4108C33 Resolvase G6O64_21400 ENOG41081XQ Conserved Protein G6O64_21405 ENOG4105WJG Glutathione G6O64_21420 ENOG4107QY8 reductase G6O64_21430 ENOG4107QY8 reductase G6O64_21435 ENOG4105CUW cytochrome C-TYPE protein G6O64_21445 ENOG4106ZCM YecM protein G6O64_21495 ENOG4108VYJ response regulator receiver protein G6O64_21505 ENOG4105BZU Histidine kinase G6O64_21510 ENOG4105C8Q Methyl-accepting chemotaxis G6O64_21515 ENOG4105C8Q Methyl-accepting chemotaxis G6O64_21520 ENOG4108V3W Chemotaxis protein, CheW G6O64_21525 ENOG4105CBS Chea signal transduction histidine kinase G6O64_21530 ENOG4105ER2 Ompa motb domain protein G6O64_21535 ENOG4107RD7 Flagellar Motor Protein, MotA G6O64_21540 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region G6O64_21555 ENOG4108VA4 Universal stress protein G6O64_21565 ENOG4108K4C ec 3.1.3.12 G6O64_21570 ENOG4105CNN ABC, transporter G6O64_21580 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator G6O64_21585 ENOG4108UEC Ferritin-like protein G6O64_21590 ENOG4105N4N Protein of unknown function (DUF2766) G6O64_21600 ENOG4105P23 (LipO)protein G6O64_21605 ENOG41090A1 ferritin G6O64_21610 ENOG4105VVZ metal-binding protein G6O64_21615 ENOG4105E0U tyrosine-specific transport protein G6O64_21620 ENOG4106RHG Yeca family G6O64_21650 ENOG4105WH1 Two component transcriptional regulator luxr family G6O64_21660 ENOG4105XVG cytoplasmic protein G6O64_21665 ENOG4105VJY transcriptional regulator G6O64_21670 ENOG4105CDA abc transporter atp-binding protein G6O64_21675 ENOG4105E5Q amino acid AbC transporter G6O64_21690 ENOG4105EAB amino acid AbC transporter G6O64_21710 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) G6O64_21745 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) G6O64_21750 ENOG4106S48 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division G6O64_21755 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A G6O64_21765 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) G6O64_21775 ENOG4105ED1 spovr family G6O64_21810 ENOG4105KT5 UmuD protein G6O64_21845 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase G6O64_21855 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium G6O64_21860 ENOG4105S66 prophage protein G6O64_21870 ENOG4107QMS site-determining protein G6O64_21900 ENOG410658X G6O64_21925 ENOG4108XDN Transcriptional regulator G6O64_21930 ENOG41064WM Uncharacterized protein YcgX G6O64_21945 ENOG4108HMX isocitrate dehydrogenase (NADP) G6O64_21950 ENOG4108R99 pseudouridine synthase G6O64_21970 ENOG4107QTF adenylosuccinate lyase G6O64_21975 ENOG4105XJC Two component transcriptional regulator (Winged helix family G6O64_21980 ENOG4105IFJ Histidine kinase G6O64_21985 ENOG4105EZE Cupin 4 family protein G6O64_22005 ENOG4105D38 putrescine abc transporter G6O64_22010 ENOG4107RUE extracellular solute-binding protein family 1 G6O64_22015 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) G6O64_22025 ENOG4105D60 lipoprotein releasing system transmembrane protein G6O64_22030 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) G6O64_22035 ENOG4105D60 lipoprotein releasing system transmembrane protein G6O64_22040 ENOG4105IQC Inner membrane protein YcfT G6O64_22045 ENOG4108JA2 transcriptioN-repair coupling factor G6O64_22055 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction G6O64_22060 ENOG4108IND Tetr family transcriptional regulator G6O64_22065 ENOG4107MBR 17 kDa surface antigen G6O64_22070 ENOG4105CEP NADH dehydrogenase G6O64_22090 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) G6O64_22095 ENOG41090DQ Lipoprotein G6O64_22100 ENOG4105K59 histidine triad (HIT) protein G6O64_22105 ENOG4105CNM Receptor G6O64_22110 ENOG4105CI1 PTS System G6O64_22115 ENOG4105F8V Hydrolase, tatD family G6O64_22120 ENOG4107QRG dna polymerase iii G6O64_22130 ENOG4105HHA aminodeoxychorismate lyase G6O64_22135 ENOG4105YAZ 4-amino-4-deoxychorismate lyase G6O64_22140 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) G6O64_22145 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) G6O64_22150 ENOG4105CHR reductase G6O64_22155 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase G6O64_22175 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein G6O64_22180 ENOG4108UHJ MAF-like protein G6O64_22185 ENOG4105EI2 Pseudouridine synthase G6O64_22190 ENOG4107QQB Ribonuclease E G6O64_22195 ENOG4105DTJ flagellar hook-associated protein G6O64_22200 ENOG4105E1Q flagellar hook-associated protein G6O64_22205 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj G6O64_22225 ENOG4108KPB Flagellar basal-body rod protein FlgF G6O64_22230 ENOG4105BZE flagellar hook protein, FlgE G6O64_22235 ENOG4105W00 Flagellar hook capping protein G6O64_22240 ENOG4108ZC9 flagellar basal-body rod protein flgc G6O64_22245 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) G6O64_22250 ENOG4105CKS Flagella basal body P-ring formation protein flgA G6O64_22255 ENOG4105M9M anti-sigma28 factor FlgM G6O64_22260 ENOG4105QVD Flagella synthesis protein FlgN G6O64_22265 ENOG4105CJR Integral membrane protein (MviN G6O64_22270 ENOG4105EP9 oxidoreductase G6O64_22280 ENOG4105D9U N-acetyltransferase G6O64_22290 ENOG4105E9S glutaredoxin 2 G6O64_22295 ENOG4105F3T (LipO)protein G6O64_22300 ENOG4105EKE dihydroorotase G6O64_22305 ENOG4105MEA DNA damage-inducible protein i G6O64_22310 ENOG4105PVA Biofilm formation regulatory protein BssS G6O64_22325 ENOG4105DS1 cytochrome b561 G6O64_22330 ENOG4108YYC ycei family G6O64_22340 ENOG4105D1S lipid A biosynthesis G6O64_22360 ENOG4105D70 Integrase catalytic subunit G6O64_22365 ENOG4105F5W AtP-binding protein G6O64_22385 ENOG4108W47 Acidic protein msyB G6O64_22390 ENOG4105NAC (LipO)protein G6O64_22395 ENOG4105VNT transposase (IS4 family) protein G6O64_22400 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) G6O64_22415 ENOG4107RZC phospholipase d G6O64_22420 ENOG4108UVJ appr-1-p processing domain protein G6O64_22445 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin G6O64_22450 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers G6O64_22475 ENOG4108XDW curli assembly protein CsgE G6O64_22480 ENOG4108WYR Curli production assembly transport component, CsgF G6O64_22485 ENOG4105P8Q Curli production assembly transport component CsgG G6O64_22490 ENOG4108UQ5 membrane protein YcdZ G6O64_22495 ENOG4107XHZ cytoplasmic chaperone TorD family protein G6O64_22505 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase G6O64_22525 ENOG4105D5M phosphate starvation-inducible protein G6O64_22535 ENOG410650H (LipO)protein G6O64_22545 ENOG4105CK7 Sodium proline symporter G6O64_22550 ENOG4105C26 Dehydrogenase G6O64_22555 ENOG4108R86 Transcriptional regulator G6O64_22610 ENOG4105C2W permease G6O64_22615 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 G6O64_22680 ENOG4105F5W AtP-binding protein G6O64_22705 ENOG4105XH3 G6O64_22710 ENOG4105D6F Phosphatase G6O64_22740 ENOG4107QY8 reductase G6O64_22745 ENOG4105CUW cytochrome C-TYPE protein G6O64_22750 ENOG4106WF9 DNA-binding transcriptional regulator TorR G6O64_22755 ENOG4108SV3 Tmao reductase system periplasmic protein tort G6O64_22760 ENOG4105BZU Histidine kinase G6O64_22770 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation G6O64_22785 ENOG4105VEQ Cold shock protein G6O64_22795 ENOG41060EU Cold shock-like protein G6O64_22805 ENOG4108Y9B (LipO)protein G6O64_22810 ENOG4108W78 Pfam:DUF1017 G6O64_22815 ENOG4105E3R (LipO)protein G6O64_22820 ENOG4105DAY polysaccharide export protein G6O64_22825 ENOG4107ZF2 Phosphatase G6O64_22830 ENOG4105D75 Capsular exopolysaccharide family G6O64_22835 ENOG4105D6F Phosphatase G6O64_22845 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii G6O64_22850 ENOG4105C4M (Ubiquinol oxidase) subunit I G6O64_22855 ENOG4105MVP hydrogenase-1 operon protein HyaF G6O64_22860 ENOG4108VXY Hydrogenase-1 operon protein HyaE G6O64_22865 ENOG4108USZ hydrogenase G6O64_22875 ENOG4105DPX Hydrogenase, large subunit G6O64_22880 ENOG4105E3S small subunit G6O64_22895 ENOG4108MN8 Membrane G6O64_22900 ENOG4108Z0T Part of a sulfur-relay system (By similarity) G6O64_22905 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 G6O64_22920 ENOG4105K4P CoA-binding domain protein G6O64_22940 ENOG41088T4 Helicase IV G6O64_22945 ENOG410901E Membrane G6O64_22950 ENOG4105EM2 membrane G6O64_22955 ENOG4108RZ1 DNA transformation protein G6O64_22965 ENOG4105UYK outer membrane protein a G6O64_22975 ENOG4105DAN ATP-dependent protease G6O64_22985 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) G6O64_22990 ENOG4108Q2G (LipO)protein G6O64_22995 ENOG4105DY2 Paraquat-inducible protein b G6O64_23000 ENOG4105F1S paraquat-inducible protein a G6O64_23005 ENOG4105C5H ABC transporter G6O64_23015 ENOG4105QVC MOSC domain-containing protein G6O64_23020 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) G6O64_23030 ENOG4106PH7 chaperone G6O64_23035 ENOG4105MX3 Fimbrial G6O64_23040 ENOG4105Q7J Fimbrial G6O64_23045 ENOG4108MDY Fimbrial G6O64_23055 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae G6O64_23060 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon G6O64_23070 ENOG4108UZX fmn reductase G6O64_23075 ENOG4105GVF (ABC) transporter G6O64_23085 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component G6O64_23095 ENOG4105CD8 aminopeptidase N G6O64_23110 ENOG4105FCK Membrane G6O64_23115 ENOG4105CGF Aromatic amino acid aminotransferase G6O64_23120 ENOG4105C5X domain protein G6O64_23125 ENOG4105EAQ (twin-arginine translocation) pathway signal G6O64_23130 ENOG4105DIT ErfK YbiS YcfS YnhG family protein G6O64_23135 ENOG4105VNT transposase (IS4 family) protein G6O64_23145 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) G6O64_23155 ENOG4106371 Methyltransferase G6O64_23160 ENOG4107S90 membrAne G6O64_23165 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups G6O64_23180 ENOG4105T0Z Conserved Protein G6O64_23195 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 G6O64_23205 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) G6O64_23215 ENOG4108K0D peptidase, M48 G6O64_23235 ENOG4107VMU Membrane G6O64_23240 ENOG4105DDY UPF0142 protein ycaO G6O64_23245 ENOG4105TMB Formate nitrite transporter G6O64_23250 ENOG4105C6N Formate acetyltransferase G6O64_23255 ENOG4105F1A Pyruvate formate-lyase G6O64_23260 ENOG4108X0B nad(p)h dehydrogenase (quinone) G6O64_23290 ENOG4105CHJ isochorismatase hydrolase G6O64_23295 ENOG4107KGK dmso reductase anchor subunit G6O64_23300 ENOG4105QAX Iron-sulfur G6O64_23305 ENOG4107QY8 reductase G6O64_23315 ENOG4105D1H recombination factor protein RarA G6O64_23325 ENOG4105CNU cell division protein FtsK G6O64_23335 ENOG4105C3M thioredoxin reductase G6O64_23340 ENOG4108JJ9 ABC, transporter G6O64_23345 ENOG4108JJ8 (ABC) transporter G6O64_23355 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) G6O64_23365 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit G6O64_23445 ENOG4105VEQ Cold shock protein G6O64_23455 ENOG4105DJY efflux transporter, rnd family, mfp subunit G6O64_23460 ENOG4108MJ5 VirK protein G6O64_23465 ENOG4105CPB ATP-dependent endonuclease of the OLD family G6O64_23480 ENOG4105DWU Membrane G6O64_23490 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) G6O64_23495 ENOG4105C7K acetolactate synthase G6O64_23500 ENOG4105C5W Aldolase G6O64_23505 ENOG4105CGD Nad-dependent epimerase dehydratase G6O64_23510 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase G6O64_23515 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase G6O64_23530 ENOG41064MM (LipO)protein G6O64_23535 ENOG4105E5Z arginine transporter ATP-binding subunit G6O64_23540 ENOG4106PMH Extracellular solute-binding protein family 3 G6O64_23545 ENOG4105GBT ABC transporter G6O64_23550 ENOG4105DMR ABC, transporter G6O64_23555 ENOG4106TNF Periplasmic binding protein G6O64_23565 ENOG4105RBQ inner membrane protein ybjO G6O64_23570 ENOG4105D38 putrescine abc transporter G6O64_23575 ENOG4105F38 ABC transporter, permease G6O64_23580 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) G6O64_23585 ENOG4107RUE extracellular solute-binding protein family 1 G6O64_23590 ENOG4108RMJ sensory transduction regulator G6O64_23600 ENOG4108DBC nitroreductase G6O64_23605 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress G6O64_23610 ENOG41090BQ Glutaredoxin G6O64_23615 ENOG4105GWF inner membrane protein YbjM G6O64_23625 ENOG4108RFG Tetr family transcriptional regulator G6O64_23630 ENOG4106UW1 Major Facilitator superfamily G6O64_23635 ENOG4108HCJ Hydrolase G6O64_23650 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase G6O64_23655 ENOG4107FB0 transcriptional regulator DeoR family G6O64_23675 ENOG4105D8V Glucose sorbosone dehydrogenase G6O64_23680 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway G6O64_23705 ENOG4105BZU Histidine kinase G6O64_23730 ENOG4105D44 asparaginase G6O64_23735 ENOG4105CVM Molybdenum cofactor synthesis domain protein G6O64_23740 ENOG4105D06 uba thif-type nad fad binding protein G6O64_23745 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) G6O64_23750 ENOG4105F1A Pyruvate formate-lyase G6O64_23760 ENOG4108HCJ Hydrolase G6O64_23765 ENOG41072TH Protein of unknown function (DUF1479) G6O64_23770 ENOG4105ETE Transcriptional regulator (LacI family G6O64_23780 ENOG4105DPW Major facilitator superfamily MFS_1 G6O64_23790 ENOG4105C5H ABC transporter G6O64_23795 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein G6O64_23800 ENOG4105F4P )-transporter G6O64_23805 ENOG4105KST dependent repressor G6O64_23815 ENOG4108I6E Sulfatase G6O64_23820 ENOG4108T1M outer membrane protein x G6O64_23830 ENOG4107AQZ Membrane G6O64_23840 ENOG4107R0W ABC transporter G6O64_23845 ENOG4105E5Q amino acid AbC transporter G6O64_23850 ENOG4105CDA abc transporter atp-binding protein G6O64_23855 ENOG4105D8X mechanosensitive ion channel G6O64_23865 ENOG4105ZY9 UPF0379 protein ybiM G6O64_23870 ENOG4108IU3 tonb-dependent siderophore receptor G6O64_23875 ENOG4105VNT transposase (IS4 family) protein G6O64_23890 ENOG4105KSC Transcriptional regulator, TraR DksA family G6O64_23895 ENOG4105VR4 UPF0379 protein ybiJ G6O64_23900 ENOG4105DG4 malate L-lactate dehydrogenase G6O64_23905 ENOG4108MTB glycosyl transferase family G6O64_23910 ENOG4105DVT helicase G6O64_23920 ENOG4105C1J atp-dependent rna helicase G6O64_23925 ENOG4107MVR Transcriptional regulator G6O64_23935 ENOG4105CJ1 ABC, transporter G6O64_23940 ENOG4107QWP ABC-2 type transporter G6O64_23945 ENOG4107QWP ABC-2 type transporter G6O64_23950 ENOG4105I9U inner membrane protein ybhQ G6O64_23955 ENOG4105X23 Endonuclease Exonuclease phosphatase G6O64_23960 ENOG4105DZQ phospholipase D Transphosphatidylase G6O64_23975 ENOG4105HFZ Membrane G6O64_23980 ENOG4108ZAF Molybdopterin G6O64_23985 ENOG4105M00 molybdopterin converting factor, subunit 1 G6O64_23995 ENOG4108RIR Molybdenum cofactor biosynthesis protein G6O64_24005 ENOG4105CHW UPF0052 protein G6O64_24015 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) G6O64_24020 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) G6O64_24035 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) G6O64_24040 ENOG4108V1U phospholipid-binding protein G6O64_24055 ENOG4108QHK Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway G6O64_24075 ENOG4108I1J Integrase G6O64_24080 ENOG4105NBR Pectinesterase G6O64_24085 ENOG4107QM5 aconitate hydratase G6O64_24095 ENOG4105F04 LysR family Transcriptional regulator G6O64_24105 ENOG4108C33 Resolvase G6O64_24135 ENOG4108N0N Phage Terminase Large Subunit G6O64_24150 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 G6O64_24155 ENOG4105KUS lysozyme G6O64_24170 ENOG410836F Transposase G6O64_24190 ENOG41087BU transcriptional repressor DicA G6O64_24215 ENOG4105JBR DNA replication protein G6O64_24230 ENOG4105WPN DNA integration recombination invertion protein G6O64_24235 ENOG4105WI6 cell killing protein encoded within cryptic prophage G6O64_24255 ENOG4108I1J Integrase G6O64_24265 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) G6O64_24270 ENOG4105E0C molybdate abc transporter G6O64_24275 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein G6O64_24285 ENOG4105F4R Transcriptional regulator mode G6O64_24290 ENOG4105DKW ABC transporter G6O64_24295 ENOG4105CMR udp-glucose 4-epimerase G6O64_24300 ENOG4105F0Z galactose-1-phosphate uridylyltransferase G6O64_24310 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) G6O64_24320 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) G6O64_24325 ENOG4105JND homeobox protein G6O64_24330 ENOG4105PGM cation diffusion facilitator family transporter G6O64_24335 ENOG4106Z1T Nicotinamide Mononucleotide Transporter G6O64_24390 ENOG4105UFD tol-pal system protein YbgF G6O64_24395 ENOG4105KCK Peptidoglycan-associated lipoprotein G6O64_24405 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA G6O64_24415 ENOG4105E02 MotA TolQ exbB proton channel G6O64_24420 ENOG4107YD3 Thioesterase G6O64_24425 ENOG4105KJB cyd operon protein YbgE G6O64_24435 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii G6O64_24440 ENOG4105C4M (Ubiquinol oxidase) subunit I G6O64_24455 ENOG4105DM4 PTS System G6O64_24460 ENOG4105FDP GntR family transcriptional regulator G6O64_24465 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha G6O64_24475 ENOG4105C7S Dehydrogenase G6O64_24480 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 G6O64_24485 ENOG4105E33 succinate dehydrogenase G6O64_24490 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) G6O64_24495 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein G6O64_24500 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit G6O64_24510 ENOG4105BZN citrate synthase G6O64_24515 ENOG4106UBK fimbrial-like adhesin protein G6O64_24735 ENOG41073YN Protein of unknown function (DUF1380) G6O64_24790 ENOG4107SKI cobyrinic Acid a,c-diamide synthase G6O64_24905 ENOG4107QHF type ii secretion system protein e G6O64_24920 ENOG4105K5T PilT protein G6O64_24980 ENOG4105CZX twitching motility protein