locus-tag	class	description
HUX90_00010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUX90_00110	COG2200	EAL domain
HUX90_00135	COG2200	EAL domain
HUX90_00140	COG0789	Transcriptional regulator
HUX90_00145	COG5562	phage envelope protein
HUX90_00160	COG0538	isocitrate dehydrogenase activity
HUX90_00165	COG1403	HNH endonuclease
HUX90_00170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HUX90_00180	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HUX90_00195	COG3778	Protein conserved in bacteria
HUX90_00200	COG3299	homolog of phage Mu protein gp47
HUX90_00220	COG4228	DNA circulation
HUX90_00240	COG4386	tail sheath protein
HUX90_00285	COG4695	Portal protein
HUX90_00295	COG1802	Transcriptional regulator
HUX90_00295	COG4626	Terminase
HUX90_00345	COG1403	HNH endonuclease
HUX90_00355	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HUX90_00370	COG1846	Transcriptional regulator
HUX90_00415	COG5532	Uncharacterized conserved protein (DUF2303)
HUX90_00420	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HUX90_00430	COG0582	viral genome integration into host DNA
HUX90_00450	COG0538	isocitrate dehydrogenase activity
HUX90_00455	COG1187	pseudouridine synthase activity
HUX90_00475	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUX90_00485	COG2205	protein histidine kinase activity
HUX90_00490	COG2850	peptidyl-arginine hydroxylation
HUX90_00500	COG3842	ATPase activity
HUX90_00510	COG1177	transmembrane transport
HUX90_00515	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HUX90_00525	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HUX90_00530	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HUX90_00535	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUX90_00545	COG4591	ABC-type transport system involved in lipoprotein release permease component
HUX90_00550	COG1136	(ABC) transporter
HUX90_00555	COG4591	ABC-type transport system involved in lipoprotein release permease component
HUX90_00560	COG4763	Acyl-transferase
HUX90_00565	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HUX90_00570	COG1388	LysM domain
HUX90_00570	COG1376	ErfK ybiS ycfS ynhG family protein
HUX90_00580	COG1309	transcriptional regulator
HUX90_00585	COG3134	Outer membrane lipoprotein
HUX90_00590	COG1252	NADH dehydrogenase
HUX90_00610	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
HUX90_00615	COG5633	Lipoprotein
HUX90_00620	COG0537	adenosine 5'-monophosphoramidase activity
HUX90_00625	COG4773	Receptor
HUX90_00630	COG1263	PTS System
HUX90_00630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUX90_00635	COG0084	hydrolase, TatD family'
HUX90_00640	COG0470	DNA polymerase III
HUX90_00650	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HUX90_00655	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUX90_00660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUX90_00670	COG1028	Short-chain dehydrogenase reductase Sdr
HUX90_00675	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HUX90_00695	COG1399	metal-binding, possibly nucleic acid-binding protein
HUX90_00700	COG0424	maF-like protein
HUX90_00705	COG0564	pseudouridine synthase activity
HUX90_00710	COG1530	ribonuclease E activity
HUX90_00715	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HUX90_00720	COG1256	bacterial-type flagellum assembly
HUX90_00725	COG3951	Flagellar rod assembly protein muramidase FlgJ
HUX90_00725	COG1705	Flagellar rod assembly protein muramidase FlgJ
HUX90_00740	COG4786	Flagellar basal body rod
HUX90_00745	COG4787	bacterial-type flagellum-dependent cell motility
HUX90_00750	COG1749	Flagellar hook protein flgE
HUX90_00755	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HUX90_00760	COG1558	bacterial-type flagellum-dependent cell motility
HUX90_00765	COG1815	bacterial-type flagellum-dependent cell motility
HUX90_00770	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
HUX90_00775	COG2747	anti-sigma28 factor FlgM
HUX90_00780	COG3418	PFAM FlgN family protein
HUX90_00785	COG0728	peptidoglycan biosynthetic process
HUX90_00790	COG0673	inositol 2-dehydrogenase activity
HUX90_00800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUX90_00810	COG2999	glutathione oxidoreductase activity
HUX90_00845	COG3038	cytochrome b561
HUX90_00850	COG2353	YceI-like domain
HUX90_00860	COG1560	Kdo2-lipid A biosynthetic process
HUX90_00875	COG5645	(Lipo)protein
HUX90_00880	COG2943	transferase activity, transferring hexosyl groups
HUX90_00895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUX90_00900	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HUX90_00925	COG2197	response regulator
HUX90_00940	COG1462	curli production assembly transport component CsgG
HUX90_00950	COG3381	protein complex oligomerization
HUX90_00975	COG1702	phosphate starvation-inducible protein PhoH
HUX90_00985	COG2822	iron ion transport
HUX90_00995	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUX90_01005	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HUX90_01005	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HUX90_01005	COG0506	proline dehydrogenase activity
HUX90_01010	COG1309	transcriptional regulator
HUX90_01045	COG2233	PERMEase
HUX90_01050	COG3729	General stress protein
HUX90_01090	COG0243	molybdopterin cofactor binding
HUX90_01095	COG3005	denitrification pathway
HUX90_01100	COG0745	RESPONSE REGULATOR receiver
HUX90_01105	COG1879	ABC-type sugar transport system periplasmic component
HUX90_01110	COG2205	protein histidine kinase activity
HUX90_01110	COG2198	Histidine kinase
HUX90_01110	COG0784	Response regulator, receiver
HUX90_01115	COG0348	domain, Protein
HUX90_01135	COG1278	Cold shock
HUX90_01140	COG1278	Cold shock
HUX90_01160	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUX90_01165	COG1596	polysaccharide export
HUX90_01170	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUX90_01175	COG3206	protein involved in exopolysaccharide biosynthesis
HUX90_01175	COG0489	protein tyrosine kinase activity
HUX90_01190	COG1294	oxidase, subunit
HUX90_01195	COG1271	oxidase subunit
HUX90_01200	COG1773	rubredoxin
HUX90_01205	COG1999	signal sequence binding
HUX90_01210	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HUX90_01215	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
HUX90_01220	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HUX90_01225	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HUX90_01235	COG0670	Belongs to the BI1 family
HUX90_01240	COG2920	part of a sulfur-relay system
HUX90_01245	COG1254	Belongs to the acylphosphatase family
HUX90_01260	COG1832	CoA-binding protein
HUX90_01275	COG0210	DNA helicase
HUX90_01280	COG3304	Inner membrane component domain
HUX90_01285	COG1289	transmembrane transporter activity
HUX90_01290	COG3070	regulator of competence-specific genes
HUX90_01310	COG1067	ATP-dependent peptidase activity
HUX90_01320	COG3130	regulation of translation
HUX90_01325	COG3009	Protein conserved in bacteria
HUX90_01330	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HUX90_01330	COG3008	intermembrane lipid transfer
HUX90_01335	COG2995	paraquat-inducible protein a
HUX90_01340	COG0488	(ABC) transporter
HUX90_01350	COG0633	Ferredoxin
HUX90_01350	COG3217	Mosc domain protein beta barrel domain protein
HUX90_01365	COG3121	Chaperone
HUX90_01370	COG3539	Fimbrial protein
HUX90_01375	COG3539	Fimbrial protein
HUX90_01380	COG3539	Fimbrial protein
HUX90_01390	COG3121	Chaperone
HUX90_01395	COG3539	Fimbrial protein
HUX90_01400	COG0431	NADPH-dependent FMN reductase
HUX90_01405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUX90_01415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUX90_01425	COG0308	aminopeptidase N
HUX90_01440	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HUX90_01445	COG1448	Aminotransferase
HUX90_01450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUX90_01455	COG3108	Peptidase M15
HUX90_01460	COG2989	Protein conserved in bacteria
HUX90_01470	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HUX90_01480	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUX90_01485	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HUX90_01490	COG3173	Aminoglycoside phosphotransferase
HUX90_01505	COG3214	Protein conserved in bacteria
HUX90_01515	COG1132	(ABC) transporter
HUX90_01520	COG0658	competence protein
HUX90_01520	COG2333	competence protein COMEC
HUX90_01530	COG0539	negative regulation of cytoplasmic translation
HUX90_01540	COG0501	Belongs to the peptidase M48B family
HUX90_01555	COG2323	membrane
HUX90_01560	COG1944	ATP diphosphatase activity
HUX90_01565	COG2116	formate transmembrane transporter activity
HUX90_01570	COG1882	Formate acetyltransferase
HUX90_01575	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HUX90_01595	COG0583	DNA-binding transcription factor activity
HUX90_01600	COG0531	amino acid
HUX90_01610	COG1335	isochorismatase
HUX90_01615	COG3302	dmso reductase anchor subunit
HUX90_01620	COG0437	4 iron, 4 sulfur cluster binding
HUX90_01625	COG0243	molybdopterin cofactor binding
HUX90_01635	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HUX90_01650	COG1522	sequence-specific DNA binding
HUX90_01655	COG0492	ferredoxin-NADP+ reductase activity
HUX90_01660	COG4988	ABC transporter
HUX90_01665	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HUX90_01685	COG0542	response to heat
HUX90_01695	COG1278	Cold shock
HUX90_01700	COG1136	(ABC) transporter
HUX90_01700	COG0577	efflux transmembrane transporter activity
HUX90_01705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUX90_01710	COG2990	Protein conserved in bacteria
HUX90_01715	COG3593	DNA synthesis involved in DNA repair
HUX90_01725	COG2431	L-lysine efflux transmembrane transporter activity
HUX90_01735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUX90_01740	COG0028	Belongs to the TPP enzyme family
HUX90_01745	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HUX90_01750	COG0702	epimerase
HUX90_01755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUX90_01760	COG3023	N-Acetylmuramoyl-L-alanine amidase
HUX90_01775	COG1126	abc transporter atp-binding protein
HUX90_01780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUX90_01785	COG4215	(ABC) transporter
HUX90_01790	COG4160	amino acid transport
HUX90_01795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUX90_01810	COG1177	transmembrane transport
HUX90_01815	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUX90_01820	COG3842	ATPase activity
HUX90_01825	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HUX90_01840	COG0778	Nitroreductase
HUX90_01850	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HUX90_01865	COG3226	Transcriptional regulator
HUX90_01870	COG0738	Major facilitator superfamily
HUX90_01875	COG0561	phosphatase activity
HUX90_01885	COG2814	Major facilitator Superfamily
HUX90_01890	COG0671	phosphoesterase, PA-phosphatase related
HUX90_01895	COG1349	DNA-binding transcription factor activity
HUX90_01900	COG1686	Belongs to the peptidase S11 family
HUX90_01905	COG0625	glutathione transferase activity
HUX90_01910	COG2133	pyrroloquinoline quinone binding
HUX90_01925	COG2199	diguanylate cyclase activity
HUX90_01930	COG2200	EAL domain
HUX90_01955	COG1446	asparaginase
HUX90_01960	COG0303	'Molybdopterin
HUX90_01965	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HUX90_01970	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUX90_01975	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HUX90_01980	COG1882	Formate acetyltransferase
HUX90_01985	COG0561	phosphatase activity
HUX90_01995	COG3547	Transposase (IS116 IS110 IS902 family)
HUX90_02000	COG0488	(ABC) transporter
HUX90_02005	COG1376	ErfK ybiS ycfS ynhG family protein
HUX90_02010	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HUX90_02015	COG1321	iron dependent repressor
HUX90_02025	COG2194	sulfuric ester hydrolase activity
HUX90_02030	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HUX90_02040	COG5006	permease, DMT superfamily
HUX90_02050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUX90_02055	COG0765	amino acid transport
HUX90_02060	COG1126	abc transporter atp-binding protein
HUX90_02065	COG0668	transmembrane transport
HUX90_02080	COG4774	siderophore transport
HUX90_02090	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HUX90_02100	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HUX90_02105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HUX90_02110	COG1199	ATP-dependent helicase activity
HUX90_02115	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
HUX90_02120	COG0513	Belongs to the DEAD box helicase family
HUX90_02125	COG1309	transcriptional regulator
HUX90_02135	COG1131	(ABC) transporter
HUX90_02140	COG0842	Transport permease protein
HUX90_02145	COG0842	Transport permease protein
HUX90_02155	COG3568	Endonuclease Exonuclease Phosphatase
HUX90_02160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUX90_02165	COG0392	lysyltransferase activity
HUX90_02170	COG0670	Belongs to the BI1 family
HUX90_02180	COG0670	Belongs to the BI1 family
HUX90_02185	COG0314	molybdopterin synthase activity
HUX90_02190	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HUX90_02200	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUX90_02210	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HUX90_02220	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HUX90_02225	COG2226	methyltransferase
HUX90_02240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUX90_02245	COG1881	PFAM PEBP family protein
HUX90_02250	COG4677	pectinesterase activity
HUX90_02255	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HUX90_02265	COG2828	Protein conserved in bacteria
HUX90_02270	COG0583	DNA-binding transcription factor activity
HUX90_02280	COG0561	phosphatase activity
HUX90_02290	COG4149	molybdate abc transporter
HUX90_02295	COG0725	ABC transporter, periplasmic molybdate-binding protein
HUX90_02305	COG3585	molybdate ion transport
HUX90_02305	COG2005	Transcriptional regulator
HUX90_02310	COG1119	ATPase activity
HUX90_02315	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUX90_02320	COG1085	galactose-1-phosphate uridylyltransferase
HUX90_02330	COG2017	converts alpha-aldose to the beta-anomer
HUX90_02340	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HUX90_02350	COG1230	cation diffusion facilitator family transporter
HUX90_02355	COG3201	nicotinamide mononucleotide transporter
HUX90_02405	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HUX90_02410	COG2885	chlorophyll binding
HUX90_02420	COG3064	Membrane
HUX90_02425	COG0848	biopolymer transport protein
HUX90_02430	COG0811	peptide transport
HUX90_02435	COG0824	Thioesterase
HUX90_02440	COG3790	cyd operon protein YbgE
HUX90_02445	COG4890	Cyd operon protein YbgT
HUX90_02450	COG1294	oxidase, subunit
HUX90_02455	COG1271	oxidase subunit
HUX90_02460	COG0383	alpha-mannosidase activity
HUX90_02465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUX90_02465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUX90_02465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUX90_02470	COG2188	Transcriptional regulator
HUX90_02475	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HUX90_02485	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUX90_02490	COG0567	Dehydrogenase, E1 component
HUX90_02495	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUX90_02500	COG1053	succinate dehydrogenase
HUX90_02505	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HUX90_02510	COG2009	succinate dehydrogenase
HUX90_02520	COG0372	Belongs to the citrate synthase family
HUX90_02525	COG3539	Fimbrial protein
HUX90_02530	COG3188	usher protein
HUX90_02535	COG3121	Chaperone
HUX90_02540	COG3539	Fimbrial protein
HUX90_02545	COG3180	Ammonia monooxygenase
HUX90_02560	COG1984	allophanate hydrolase subunit 2
HUX90_02565	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HUX90_02570	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HUX90_02580	COG0415	Belongs to the DNA photolyase family
HUX90_02585	COG3272	Protein of unknown function (DUF1722)
HUX90_02605	COG3209	COG3209 Rhs family protein
HUX90_02615	COG3209	COG3209 Rhs family protein
HUX90_02645	COG2205	protein histidine kinase activity
HUX90_02650	COG0745	RESPONSE REGULATOR receiver
HUX90_02660	COG1982	Orn Lys Arg decarboxylase major
HUX90_02665	COG0531	amino acid
HUX90_02670	COG0033	Phosphoglucomutase
HUX90_02675	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HUX90_02680	COG0596	Alpha beta hydrolase
HUX90_02690	COG0716	FMN binding
HUX90_02700	COG0735	belongs to the Fur family
HUX90_02720	COG2190	(PTS) system
HUX90_02720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUX90_02720	COG1263	PTS System
HUX90_02730	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HUX90_02735	COG1846	Transcriptional regulator
HUX90_02735	COG1940	carbohydrate kinase activity
HUX90_02740	COG0647	UMP catabolic process
HUX90_02745	COG0367	asparagine synthase
HUX90_02785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUX90_02795	COG1702	phosphate starvation-inducible protein PhoH
HUX90_02805	COG4535	Mg2 and Co2 transporter CorC
HUX90_02810	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HUX90_02820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUX90_02825	COG0765	amino acid transport
HUX90_02830	COG0765	amino acid transport
HUX90_02835	COG1126	abc transporter atp-binding protein
HUX90_02845	COG0443	Heat shock 70 kDa protein
HUX90_02850	COG2214	Heat shock protein DnaJ domain protein
HUX90_02860	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HUX90_02865	COG2214	Heat shock protein DnaJ domain protein
HUX90_02875	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HUX90_02880	COG2888	peptidyl-tyrosine sulfation
HUX90_02895	COG1466	dna polymerase III delta subunit
HUX90_02910	COG0799	negative regulation of ribosome biogenesis
HUX90_02920	COG0768	penicillin binding
HUX90_02930	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HUX90_02935	COG1686	Belongs to the peptidase S11 family
HUX90_02950	COG0583	DNA-binding transcription factor activity
HUX90_02960	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUX90_02965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUX90_02985	COG3069	C4-dicarboxylate transmembrane transporter activity
HUX90_02990	COG4565	transcriptional regulatory protein
HUX90_02995	COG3290	protein histidine kinase activity
HUX90_03000	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HUX90_03010	COG2301	Belongs to the HpcH HpaI aldolase family
HUX90_03015	COG3051	citrate lyase alpha subunit
HUX90_03030	COG0471	metal ion transport
HUX90_03035	COG3719	Belongs to the RNase T2 family
HUX90_03040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUX90_03045	COG1063	alcohol dehydrogenase
HUX90_03050	COG0589	response to stress
HUX90_03055	COG3634	alkyl hydroperoxide reductase activity
HUX90_03060	COG0450	alkyl hydroperoxide reductase
HUX90_03065	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUX90_03070	COG0583	DNA-binding transcription factor activity
HUX90_03075	COG3969	phosphoadenosine phosphosulfate
HUX90_03080	COG1475	DNA binding
HUX90_03085	COG0436	Aminotransferase
HUX90_03090	COG0371	Dehydrogenase
HUX90_03095	COG2879	small protein
HUX90_03100	COG1966	Carbon starvation protein
HUX90_03105	COG2050	protein possibly involved in aromatic compounds catabolism
HUX90_03110	COG1028	Short-chain dehydrogenase reductase Sdr
HUX90_03115	COG3433	isochorismatase activity
HUX90_03115	COG1535	isochorismatase
HUX90_03120	COG1021	2,3-dihydroxybenzoate-AMP ligase
HUX90_03125	COG1169	isochorismate synthase
HUX90_03130	COG4592	Periplasmic binding protein
HUX90_03140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUX90_03145	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUX90_03150	COG1120	ATPase activity
HUX90_03155	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HUX90_03160	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HUX90_03160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUX90_03165	COG3251	PFAM MbtH domain protein
HUX90_03170	COG2382	esterase
HUX90_03175	COG4771	TonB-dependent receptor
HUX90_03180	COG2977	Belongs to the P-Pant transferase superfamily
HUX90_03205	COG2315	Protein conserved in bacteria
HUX90_03210	COG0778	Nitroreductase
HUX90_03215	COG0668	transmembrane transport
HUX90_03220	COG1113	amino acid transport
HUX90_03225	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUX90_03230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUX90_03235	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUX90_03240	COG1538	Outer membrane efflux protein
HUX90_03245	COG0745	RESPONSE REGULATOR receiver
HUX90_03250	COG5002	protein histidine kinase activity
HUX90_03255	COG3501	Rhs element vgr protein
HUX90_03265	COG4104	PAAR repeat-containing protein
HUX90_03265	COG3209	COG3209 Rhs family protein
HUX90_03295	COG5433	transposase activity
HUX90_03300	COG1215	transferase activity, transferring glycosyl groups
HUX90_03305	COG4783	chaperone-mediated protein folding
HUX90_03315	COG2207	Transcriptional regulator
HUX90_03325	COG2197	response regulator
HUX90_03330	COG3539	Fimbrial protein
HUX90_03335	COG3539	Fimbrial protein
HUX90_03345	COG3121	Chaperone
HUX90_03350	COG3539	Fimbrial protein
HUX90_03360	COG2501	S4 domain
HUX90_03365	COG1988	membrane-bound metal-dependent
HUX90_03375	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUX90_03385	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HUX90_03390	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HUX90_03395	COG0549	Belongs to the carbamate kinase family
HUX90_03405	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HUX90_03410	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HUX90_03415	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HUX90_03420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUX90_03425	COG3257	ureidoglycine aminohydrolase activity
HUX90_03430	COG1929	Belongs to the glycerate kinase type-1 family
HUX90_03435	COG2233	PERMEase
HUX90_03445	COG1953	Uracil, thiamine, allantoin
HUX90_03450	COG2084	Dehydrogenase
HUX90_03455	COG3622	Belongs to the hyi family
HUX90_03460	COG3960	tartronate-semialdehyde synthase activity
HUX90_03465	COG1414	Transcriptional regulator
HUX90_03475	COG0583	DNA-binding transcription factor activity
HUX90_03485	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HUX90_03490	COG4181	ATPase activity
HUX90_03495	COG2755	lipolytic protein G-D-S-L family
HUX90_03500	COG0300	oxidoreductase activity
HUX90_03505	COG3118	belongs to the thioredoxin family
HUX90_03510	COG0390	transport system, permease component
HUX90_03515	COG4619	ABC transporter
HUX90_03520	COG0330	HflC and HflK could
HUX90_03525	COG1585	Membrane protein implicated in regulation of membrane protease activity
HUX90_03530	COG0789	Transcriptional regulator
HUX90_03535	COG0531	amino acid
HUX90_03540	COG2066	Belongs to the glutaminase family
HUX90_03545	COG2217	Heavy metal translocating P-type atpase
HUX90_03550	COG3093	addiction module antidote protein HigA
HUX90_03555	COG3735	TraB family
HUX90_03560	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HUX90_03565	COG0737	Belongs to the 5'-nucleotidase family
HUX90_03570	COG2223	nitrite transmembrane transporter activity
HUX90_03575	COG4651	solute:proton antiporter activity
HUX90_03575	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HUX90_03580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUX90_03615	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HUX90_03625	COG2832	Protein of unknown function (DUF454)
HUX90_03630	COG3923	Primosomal replication protein n
HUX90_03640	COG1196	nuclear chromosome segregation
HUX90_03640	COG3264	Mechanosensitive ion channel
HUX90_03645	COG1309	transcriptional regulator
HUX90_03650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUX90_03655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUX90_03670	COG0110	maltose O-acetyltransferase activity
HUX90_03680	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HUX90_03685	COG5507	3-demethylubiquinone-9 3-methyltransferase
HUX90_03695	COG3695	enzyme binding
HUX90_03700	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HUX90_03705	COG1946	Acyl-CoA thioesterase
HUX90_03710	COG0004	ammonium transporteR
HUX90_03715	COG0347	Belongs to the P(II) protein family
HUX90_03720	COG1132	(ABC) transporter
HUX90_03725	COG1132	(ABC) transporter
HUX90_03730	COG1522	sequence-specific DNA binding
HUX90_03740	COG4533	DNA binding
HUX90_03750	COG0824	Thioesterase
HUX90_03755	COG1555	photosystem II stabilization
HUX90_03760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUX90_03765	COG0776	regulation of translation
HUX90_03770	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HUX90_03790	COG0271	Belongs to the BolA IbaG family
HUX90_03795	COG3056	Lipoprotein
HUX90_03800	COG2223	nitrite transmembrane transporter activity
HUX90_03805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HUX90_03810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUX90_03815	COG1845	cytochrome c oxidase, subunit III
HUX90_03820	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HUX90_03845	COG2814	Major facilitator Superfamily
HUX90_03855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HUX90_03860	COG0693	protein deglycase activity
HUX90_03875	COG0142	geranyltranstransferase activity
HUX90_03885	COG0667	Aldo Keto reductase
HUX90_03890	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HUX90_03895	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HUX90_03910	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUX90_03910	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUX90_03920	COG4238	major outer membrane lipoprotein
HUX90_03925	COG3248	Nucleoside-binding outer membrane protein
HUX90_03930	COG1403	HNH endonuclease
HUX90_03935	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUX90_03940	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUX90_03945	COG1862	Preprotein translocase
HUX90_03965	COG0366	Alpha amylase catalytic
HUX90_03970	COG1113	amino acid transport
HUX90_03975	COG1114	Component of the transport system for branched-chain amino acids
HUX90_03980	COG5002	protein histidine kinase activity
HUX90_03985	COG0745	RESPONSE REGULATOR receiver
HUX90_03990	COG0420	3'-5' exonuclease activity
HUX90_03995	COG0419	ATPase involved in DNA repair
HUX90_04000	COG2814	Major facilitator Superfamily
HUX90_04005	COG1940	carbohydrate kinase activity
HUX90_04030	COG4126	flavin adenine dinucleotide binding
HUX90_04050	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HUX90_04055	COG3706	GGDEF domain
HUX90_04065	COG1785	Belongs to the alkaline phosphatase family
HUX90_04080	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUX90_04100	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HUX90_04105	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUX90_04110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUX90_04115	COG3468	outer membrane autotransporter barrel domain protein
HUX90_04120	COG0113	porphobilinogen synthase activity
HUX90_04125	COG2175	clavaminate synthase activity
HUX90_04130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUX90_04140	COG4521	taurine ABC transporter
HUX90_04145	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUX90_04150	COG1215	transferase activity, transferring glycosyl groups
HUX90_04180	COG3547	Transposase (IS116 IS110 IS902 family)
HUX90_04185	COG3122	Protein conserved in bacteria
HUX90_04190	COG2814	Major facilitator Superfamily
HUX90_04225	COG1414	Transcriptional regulator
HUX90_04230	COG1609	Transcriptional regulator
HUX90_04240	COG2223	nitrite transmembrane transporter activity
HUX90_04245	COG0110	maltose O-acetyltransferase activity
HUX90_04250	COG2807	transmembrane transport
HUX90_04260	COG0288	reversible hydration of carbon dioxide
HUX90_04265	COG0583	DNA-binding transcription factor activity
HUX90_04270	COG0402	S-adenosylhomocysteine deaminase activity
HUX90_04275	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HUX90_04280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUX90_04285	COG2079	MmgE PrpD family protein
HUX90_04290	COG0372	Belongs to the citrate synthase family
HUX90_04295	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HUX90_04300	COG3829	transcription factor binding
HUX90_04310	COG1280	lysine exporter protein (LysE YggA)
HUX90_04325	COG1064	alcohol dehydrogenase
HUX90_04335	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUX90_04340	COG1129	ABC transporter
HUX90_04345	COG1879	ABC-type sugar transport system periplasmic component
HUX90_04355	COG0402	S-adenosylhomocysteine deaminase activity
HUX90_04360	COG0549	Belongs to the carbamate kinase family
HUX90_04365	COG1304	FMN binding
HUX90_04370	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HUX90_04380	COG0666	response to abiotic stimulus
HUX90_04390	COG0583	DNA-binding transcription factor activity
HUX90_04395	COG2200	EAL domain
HUX90_04395	COG2771	luxR family
HUX90_04405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUX90_04430	COG0582	viral genome integration into host DNA
HUX90_04435	COG2771	luxR family
HUX90_04435	COG2200	EAL domain
HUX90_04450	COG3468	outer membrane autotransporter barrel domain protein
HUX90_04460	COG1556	Lactate utilization protein
HUX90_04465	COG1139	Iron-sulfur cluster binding protein
HUX90_04470	COG0247	lactate metabolic process
HUX90_04475	COG2207	Transcriptional regulator
HUX90_04480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUX90_04490	COG3059	membrane
HUX90_04495	COG0656	L-ascorbic acid biosynthetic process
HUX90_04500	COG2207	Transcriptional regulator
HUX90_04500	COG3708	Transcriptional regulator
HUX90_04505	COG1388	LysM domain
HUX90_04545	COG3188	usher protein
HUX90_04555	COG3121	Chaperone
HUX90_04560	COG0727	PFAM Uncharacterised protein family (UPF0153)
HUX90_04565	COG3477	response to acidic pH
HUX90_04570	COG2080	2 iron, 2 sulfur cluster binding
HUX90_04575	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUX90_04580	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUX90_04585	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HUX90_04590	COG0583	DNA-binding transcription factor activity
HUX90_04600	COG0464	growth
HUX90_04660	COG0582	viral genome integration into host DNA
HUX90_04680	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HUX90_04700	COG2195	Cleaves the N-terminal amino acid of tripeptides
HUX90_04705	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUX90_04710	COG1690	Belongs to the RtcB family
HUX90_04715	COG0454	-acetyltransferase
HUX90_04745	COG0791	NLP P60 protein
HUX90_04750	COG3077	Addiction module antitoxin, RelB DinJ family
HUX90_04755	COG3041	Addiction module toxin RelE StbE family
HUX90_04760	COG3034	peptidoglycan biosynthetic process
HUX90_04765	COG0121	glutamine amidotransferase
HUX90_04775	COG1960	acyl-CoA dehydrogenase activity
HUX90_04785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUX90_04835	COG3209	COG3209 Rhs family protein
HUX90_04840	COG3501	Rhs element vgr protein
HUX90_04925	COG3157	Type VI secretion system effector, Hcp
HUX90_04930	COG4104	PAAR repeat-containing protein
HUX90_04950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUX90_04960	COG2226	methyltransferase
HUX90_04970	COG0741	lytic transglycosylase activity
HUX90_04970	COG1388	LysM domain
HUX90_04975	COG2226	methyltransferase
HUX90_04985	COG0583	DNA-binding transcription factor activity
HUX90_04990	COG0656	L-ascorbic acid biosynthetic process
HUX90_05025	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HUX90_05030	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUX90_05035	COG2011	ABC-type metal ion transport system permease component
HUX90_05040	COG1464	Belongs to the NlpA lipoprotein family
HUX90_05050	COG1720	tRNA m6t6A37 methyltransferase activity
HUX90_05065	COG3547	Transposase (IS116 IS110 IS902 family)
HUX90_05070	COG3015	lipoprotein NlpE involved in copper resistance
HUX90_05075	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUX90_05080	COG4681	YaeQ
HUX90_05090	COG4568	rho-dependent transcription termination
HUX90_05100	COG0346	lactoylglutathione lyase activity
HUX90_05115	COG0587	DNA-directed DNA polymerase activity
HUX90_05140	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUX90_05145	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HUX90_05155	COG0750	zinc metalloprotease
HUX90_05160	COG0575	Belongs to the CDS family
HUX90_05165	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUX90_05170	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HUX90_05195	COG0024	Methionine aminopeptidase
HUX90_05215	COG3835	regulator
HUX90_05220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUX90_05235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUX90_05240	COG2860	membrane
HUX90_05265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUX90_05270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUX90_05275	COG1120	ATPase activity
HUX90_05280	COG4774	siderophore transport
HUX90_05285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUX90_05290	COG1643	Atp-dependent helicase
HUX90_05295	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HUX90_05305	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HUX90_05315	COG0617	tRNA 3'-terminal CCA addition
HUX90_05320	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HUX90_05325	COG3539	Fimbrial protein
HUX90_05330	COG3121	Chaperone
HUX90_05335	COG3188	usher protein
HUX90_05340	COG3539	Fimbrial protein
HUX90_05345	COG3539	Fimbrial protein
HUX90_05350	COG3539	Fimbrial protein
HUX90_05355	COG3539	Fimbrial protein
HUX90_05370	COG5464	transposase or invertase
HUX90_05380	COG0726	polysaccharide deacetylase
HUX90_05385	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUX90_05390	COG0842	Transport permease protein
HUX90_05395	COG1131	(ABC) transporter
HUX90_05400	COG0288	reversible hydration of carbon dioxide
HUX90_05405	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HUX90_05410	COG4993	Dehydrogenase
HUX90_05415	COG3547	Transposase (IS116 IS110 IS902 family)
HUX90_05420	COG2132	Multicopper oxidase
HUX90_05445	COG1049	propionate catabolic process, 2-methylcitrate cycle
HUX90_05450	COG3064	Membrane
HUX90_05455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUX90_05460	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUX90_05465	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HUX90_05470	COG2186	Transcriptional regulator
HUX90_05475	COG1113	amino acid transport
HUX90_05480	COG3725	Membrane protein required for beta-lactamase induction
HUX90_05485	COG3023	N-Acetylmuramoyl-L-alanine amidase
HUX90_05490	COG0157	Belongs to the NadC ModD family
HUX90_05495	COG4969	Belongs to the N-Me-Phe pilin family
HUX90_05500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HUX90_05505	COG1459	type II secretion system
HUX90_05515	COG0237	dephospho-CoA kinase activity
HUX90_05530	COG0494	nUDIX hydrolase
HUX90_05550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HUX90_05555	COG0849	cell division
HUX90_05560	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HUX90_05565	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUX90_05580	COG0772	Belongs to the SEDS family
HUX90_05595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HUX90_05600	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HUX90_05605	COG0768	penicillin binding
HUX90_05610	COG3116	cell division
HUX90_05625	COG1609	Transcriptional regulator
HUX90_05635	COG0440	acetolactate synthase activity
HUX90_05640	COG0028	Belongs to the TPP enzyme family
HUX90_05645	COG0583	DNA-binding transcription factor activity
HUX90_05660	COG0473	3-isopropylmalate dehydrogenase activity
HUX90_05675	COG2814	Major facilitator Superfamily
HUX90_05690	COG4143	(ABC) transporter
HUX90_05695	COG1178	ABC-type Fe3 transport system permease component
HUX90_05705	COG0586	Pfam SNARE associated Golgi protein
HUX90_05710	COG4977	sequence-specific DNA binding
HUX90_05725	COG0235	Class ii aldolase
HUX90_05730	COG0417	DNA replication proofreading
HUX90_05740	COG0564	pseudouridine synthase activity
HUX90_05745	COG3547	Transposase (IS116 IS110 IS902 family)
HUX90_05750	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HUX90_05755	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HUX90_05760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUX90_05785	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HUX90_05800	COG2271	Major facilitator Superfamily
HUX90_05805	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HUX90_05810	COG0644	oxidoreductase
HUX90_05860	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUX90_05865	COG0505	Belongs to the CarA family
HUX90_05885	COG1047	Peptidyl-prolyl cis-trans
HUX90_05900	COG0196	riboflavin kinase activity
HUX90_05930	COG0583	DNA-binding transcription factor activity
HUX90_05960	COG4735	regulation of single-species biofilm formation
HUX90_05965	COG1584	GPR1 FUN34 yaaH family protein
HUX90_05970	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUX90_05975	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUX90_05980	COG1115	amino acid carrier protein
HUX90_05990	COG3547	Transposase (IS116 IS110 IS902 family)
HUX90_06000	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUX90_06010	COG0527	aspartate kinase activity
HUX90_06010	COG0460	homoserine dehydrogenase
HUX90_06020	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HUX90_06030	COG0745	RESPONSE REGULATOR receiver
HUX90_06035	COG4452	Inner membrane protein CreD
HUX90_06040	COG2205	protein histidine kinase activity
HUX90_06045	COG0745	RESPONSE REGULATOR receiver
HUX90_06050	COG3045	CreA protein
HUX90_06055	COG2207	Transcriptional regulator
HUX90_06055	COG3708	Transcriptional regulator
HUX90_06075	COG0741	lytic transglycosylase activity
HUX90_06080	COG0488	(ABC) transporter
HUX90_06085	COG1056	cytidyltransferase-related domain
HUX90_06085	COG3172	ATPase kinase involved in NAD metabolism
HUX90_06090	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HUX90_06095	COG0560	Phosphoserine phosphatase
HUX90_06100	COG3726	membrane protein affecting hemolysin expression
HUX90_06135	COG1328	CTP reductase activity
HUX90_06140	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HUX90_06145	COG0084	hydrolase, TatD family'
HUX90_06150	COG4667	esterase of the alpha-beta hydrolase superfamily
HUX90_06160	COG2823	Periplasmic or secreted lipoprotein
HUX90_06170	COG1011	Hydrolase
HUX90_06175	COG0456	acetyltransferase
HUX90_06180	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HUX90_06210	COG4114	ferric iron reductase
HUX90_06215	COG2197	response regulator
HUX90_06220	COG2197	response regulator
HUX90_06225	COG2966	Psort location CytoplasmicMembrane, score
HUX90_06240	COG1484	DNA-dependent DNA replication
HUX90_06255	COG1063	alcohol dehydrogenase
HUX90_06260	COG1802	Transcriptional regulator
HUX90_06265	COG2271	Major facilitator Superfamily
HUX90_06270	COG0840	transmembrane signaling receptor activity
HUX90_06275	COG1846	Transcriptional regulator
HUX90_06280	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUX90_06285	COG1012	belongs to the aldehyde dehydrogenase family
HUX90_06290	COG3384	dioxygenase
HUX90_06300	COG3971	2-oxopent-4-enoate hydratase activity
HUX90_06320	COG2368	4-hydroxyphenylacetate
HUX90_06325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUX90_06330	COG1966	Carbon starvation protein
HUX90_06335	COG2879	small protein
HUX90_06340	COG0523	cobalamin synthesis protein
HUX90_06350	COG5457	Domain of unknown function (DUF1127)
HUX90_06355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUX90_06365	COG2814	Major facilitator Superfamily
HUX90_06370	COG2733	membrane
HUX90_06375	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HUX90_06380	COG1924	4 iron, 4 sulfur cluster binding
HUX90_06395	COG0477	Major facilitator Superfamily
HUX90_06405	COG3366	ferrous iron transmembrane transporter activity
HUX90_06410	COG0700	Nucleoside recognition
HUX90_06415	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HUX90_06420	COG0583	DNA-binding transcription factor activity
HUX90_06440	COG2186	Transcriptional regulator
HUX90_06445	COG0246	Mannitol dehydrogenase
HUX90_06455	COG2610	gluconate transmembrane transporter activity
HUX90_06460	COG3539	Fimbrial protein
HUX90_06465	COG3539	Fimbrial protein
HUX90_06470	COG3539	Fimbrial protein
HUX90_06475	COG3188	usher protein
HUX90_06480	COG3121	Chaperone
HUX90_06485	COG3539	Fimbrial protein
HUX90_06490	COG3539	Fimbrial protein
HUX90_06495	COG4974	Belongs to the 'phage' integrase family
HUX90_06500	COG0582	viral genome integration into host DNA
HUX90_06505	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HUX90_06560	COG1064	alcohol dehydrogenase
HUX90_06565	COG0433	COG0433 Predicted ATPase
HUX90_06570	COG0795	lipopolysaccharide-transporting ATPase activity
HUX90_06575	COG0795	lipopolysaccharide-transporting ATPase activity
HUX90_06585	COG2927	DNA polymerase III (CHI subunit)
HUX90_06590	COG0525	valine-tRNA ligase activity
HUX90_06595	COG4269	membrane
HUX90_06600	COG0456	acetyltransferase
HUX90_06605	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
HUX90_06630	COG2731	YhcH YjgK YiaL family protein
HUX90_06640	COG1028	Short-chain dehydrogenase reductase Sdr
HUX90_06645	COG0251	oxidation-reduction process
HUX90_06665	COG0251	oxidation-reduction process
HUX90_06675	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUX90_06685	COG1609	Transcriptional regulator
HUX90_06690	COG1263	PTS System
HUX90_06690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUX90_06695	COG0366	Alpha amylase catalytic
HUX90_06700	COG1328	CTP reductase activity
HUX90_06705	COG0602	queuosine metabolic process
HUX90_06710	COG3783	Cytochrome b(562)
HUX90_06715	COG0312	modulator of DNA gyrase
HUX90_06725	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUX90_06735	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUX90_06740	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUX90_06745	COG1129	ABC transporter
HUX90_06750	COG1879	ABC-type sugar transport system periplasmic component
HUX90_06755	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HUX90_06760	COG2337	Toxic component of a toxin-antitoxin (TA) module
HUX90_06765	COG2336	PFAM SpoVT AbrB
HUX90_06770	COG2105	PFAM AIG2 family protein
HUX90_06775	COG2911	Protein conserved in bacteria
HUX90_06780	COG0729	surface antigen
HUX90_06790	COG1253	flavin adenine dinucleotide binding
HUX90_06800	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HUX90_06805	COG1218	3'(2'),5'-bisphosphate nucleotidase
HUX90_06810	COG0737	Belongs to the 5'-nucleotidase family
HUX90_06815	COG1733	regulation of RNA biosynthetic process
HUX90_06820	COG0702	epimerase
HUX90_06825	COG0697	spore germination
HUX90_06835	COG1113	amino acid transport
HUX90_06840	COG0545	Peptidyl-prolyl cis-trans isomerase
HUX90_06845	COG3061	Opacity-associated protein A
HUX90_06850	COG1309	transcriptional regulator
HUX90_06865	COG1024	Enoyl-CoA hydratase
HUX90_06870	COG4670	ketone body catabolic process
HUX90_06875	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HUX90_06880	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HUX90_06890	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HUX90_06900	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUX90_06935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUX90_06940	COG3414	Phosphotransferase system galactitol-specific IIB component
HUX90_06945	COG3037	sugar-specific permease SgaT UlaA
HUX90_06960	COG1073	alpha beta
HUX90_06965	COG3650	response to hydrogen peroxide
HUX90_06975	COG1960	acyl-CoA dehydrogenase activity
HUX90_06980	COG0754	glutathionylspermidine amidase activity
HUX90_06985	COG5463	Belongs to the UPF0441 family
HUX90_06990	COG3766	membrane
HUX90_07000	COG1842	Phage shock protein A
HUX90_07005	COG3789	protein conserved in bacteria
HUX90_07010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUX90_07015	COG0557	exoribonuclease II activity
HUX90_07030	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HUX90_07035	COG0330	HflC and HflK could
HUX90_07040	COG0330	HflC and HflK could
HUX90_07045	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUX90_07065	COG0860	N-Acetylmuramoyl-L-alanine amidase
HUX90_07070	COG0802	atpase or kinase
HUX90_07075	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HUX90_07075	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HUX90_07080	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HUX90_07120	COG3264	Mechanosensitive ion channel
HUX90_07120	COG1511	domain protein
HUX90_07125	COG0531	amino acid
HUX90_07135	COG1053	succinate dehydrogenase
HUX90_07140	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUX90_07155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUX90_07160	COG3040	lipid binding
HUX90_07165	COG2076	Multidrug Resistance protein
HUX90_07170	COG5510	response to toxic substance
HUX90_07175	COG5510	response to toxic substance
HUX90_07185	COG1509	lysine 2,3-aminomutase activity
HUX90_07210	COG0531	amino acid
HUX90_07215	COG3030	protein affecting phage T7 exclusion by the F plasmid
HUX90_07220	COG1027	Aspartate ammonia-lyase
HUX90_07225	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HUX90_07240	COG1309	transcriptional regulator
HUX90_07250	COG3710	Transcriptional regulator
HUX90_07255	COG0531	amino acid
HUX90_07260	COG1982	Orn Lys Arg decarboxylase major
HUX90_07265	COG3104	oligopeptide transport
HUX90_07270	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUX90_07285	COG2388	GCN5-related N-acetyl-transferase
HUX90_07290	COG3592	Divergent 4Fe-4S mono-cluster
HUX90_07295	COG3290	protein histidine kinase activity
HUX90_07300	COG4565	transcriptional regulatory protein
HUX90_07305	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HUX90_07310	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HUX90_07310	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HUX90_07315	COG3647	Membrane
HUX90_07320	COG2211	Major facilitator Superfamily
HUX90_07325	COG1486	melibiose metabolic process
HUX90_07330	COG2169	Transcriptional regulator
HUX90_07335	COG1982	Orn Lys Arg decarboxylase major
HUX90_07340	COG2207	Transcriptional regulator
HUX90_07345	COG0531	amino acid
HUX90_07350	COG2194	sulfuric ester hydrolase activity
HUX90_07355	COG0745	RESPONSE REGULATOR receiver
HUX90_07360	COG0642	Histidine kinase
HUX90_07370	COG0477	Major facilitator Superfamily
HUX90_07385	COG2824	Alkylphosphonate utilization operon protein PhnA
HUX90_07390	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HUX90_07400	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HUX90_07405	COG3639	organic phosphonate transmembrane transporter activity
HUX90_07410	COG2188	Transcriptional regulator
HUX90_07415	COG3624	Phosphonate C-P lyase system protein PhnG
HUX90_07420	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HUX90_07425	COG3626	phosphonate metabolism
HUX90_07430	COG3627	carbon phosphorus lyase activity
HUX90_07435	COG4107	phosphonate C-P lyase system protein PhnK
HUX90_07440	COG4778	phosphonate C-P lyase system protein PhnL
HUX90_07445	COG3454	Phosphonate metabolism
HUX90_07450	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
HUX90_07455	COG0456	acetyltransferase
HUX90_07460	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HUX90_07470	COG0698	ribose 5-phosphate isomerase
HUX90_07475	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HUX90_07485	COG1566	PFAM secretion protein HlyD family protein
HUX90_07505	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HUX90_07510	COG1301	dicarboxylic acid transport
HUX90_07515	COG4235	cytochrome complex assembly
HUX90_07520	COG3088	subunit of a heme lyase
HUX90_07525	COG1138	Cytochrome C-type biogenesis protein
HUX90_07530	COG3301	Polysulphide reductase, NrfD
HUX90_07535	COG0437	4 iron, 4 sulfur cluster binding
HUX90_07540	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HUX90_07550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUX90_07555	COG3162	membrane
HUX90_07565	COG1357	PFAM Pentapeptide repeats (8 copies)
HUX90_07570	COG0025	NhaP-type Na H and K H
HUX90_07575	COG2252	PERMEase
HUX90_07580	COG0789	Transcriptional regulator
HUX90_07585	COG2207	Transcriptional regulator
HUX90_07590	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HUX90_07600	COG0629	single-stranded DNA binding
HUX90_07605	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUX90_07610	COG2315	Protein conserved in bacteria
HUX90_07615	COG0432	Pfam Uncharacterised protein family UPF0047
HUX90_07620	COG3700	Belongs to the class B bacterial acid phosphatase family
HUX90_07635	COG1448	Aminotransferase
HUX90_07640	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUX90_07645	COG0305	Participates in initiation and elongation during chromosome replication
HUX90_07650	COG0604	alcohol dehydrogenase
HUX90_07660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HUX90_07670	COG0735	belongs to the Fur family
HUX90_07675	COG3237	CsbD-like
HUX90_07680	COG0534	Mate efflux family protein
HUX90_07690	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HUX90_07725	COG3842	ATPase activity
HUX90_07730	COG2182	Extracellular solute-binding protein
HUX90_07735	COG1175	transmembrane transport
HUX90_07740	COG3833	ABC-type maltose transport systems, permease component
HUX90_07745	COG2814	Major facilitator Superfamily
HUX90_07745	COG0477	Major facilitator Superfamily
HUX90_07760	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUX90_07785	COG0527	aspartate kinase activity
HUX90_07790	COG0542	response to heat
HUX90_07795	COG3541	Predicted nucleotidyltransferase
HUX90_07810	COG1187	pseudouridine synthase activity
HUX90_07820	COG1283	sodium-dependent phosphate transmembrane transporter activity
HUX90_07825	COG1410	methionine synthase
HUX90_07825	COG0646	methionine synthase
HUX90_07830	COG1414	Transcriptional regulator
HUX90_07845	COG2224	Isocitrate lyase
HUX90_07850	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HUX90_07860	COG0456	acetyltransferase
HUX90_07890	COG0151	Belongs to the GarS family
HUX90_07895	COG2204	response regulator
HUX90_07900	COG4191	Histidine kinase
HUX90_07905	COG3678	ATP-independent chaperone mediated protein folding
HUX90_07920	COG3068	Protein conserved in bacteria
HUX90_07955	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HUX90_07960	COG2104	thiamine diphosphate biosynthetic process
HUX90_07970	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HUX90_08010	COG0250	Participates in transcription elongation, termination and antitermination
HUX90_08015	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HUX90_08050	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HUX90_08050	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HUX90_08100	COG1309	transcriptional regulator
HUX90_08110	COG0583	DNA-binding transcription factor activity
HUX90_08115	COG2271	Major facilitator Superfamily
HUX90_08120	COG4948	Mandelate Racemase Muconate Lactonizing
HUX90_08135	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HUX90_08150	COG2194	sulfuric ester hydrolase activity
HUX90_08155	COG2207	Transcriptional regulator
HUX90_08160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUX90_08165	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HUX90_08170	COG1882	Formate acetyltransferase
HUX90_08175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUX90_08180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUX90_08185	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUX90_08185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUX90_08185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUX90_08190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUX90_08195	COG0371	Dehydrogenase
HUX90_08200	COG3738	Protein conserved in bacteria
HUX90_08205	COG0697	spore germination
HUX90_08215	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HUX90_08220	COG0527	aspartate kinase activity
HUX90_08220	COG0460	homoserine dehydrogenase
HUX90_08225	COG0626	cystathionine gamma-synthase activity
HUX90_08235	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HUX90_08250	COG3209	COG3209 Rhs family protein
HUX90_08260	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HUX90_08265	COG1609	Transcriptional regulator
HUX90_08270	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HUX90_08285	COG1575	Belongs to the MenA family. Type 1 subfamily
HUX90_08300	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUX90_08310	COG1494	fructose-1,6-bisphosphatase
HUX90_08320	COG0589	response to stress
HUX90_08325	COG3691	Protein conserved in bacteria
HUX90_08330	COG3152	Membrane
HUX90_08350	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HUX90_08365	COG3678	ATP-independent chaperone mediated protein folding
HUX90_08370	COG0745	RESPONSE REGULATOR receiver
HUX90_08375	COG2205	protein histidine kinase activity
HUX90_08380	COG2258	MOSC domain
HUX90_08390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HUX90_08430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUX90_08435	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUX90_08435	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUX90_08440	COG1363	Peptidase, m42
HUX90_08445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUX90_08445	COG3711	transcriptional antiterminator
HUX90_08465	COG0437	4 iron, 4 sulfur cluster binding
HUX90_08470	COG2864	formate dehydrogenase
HUX90_08480	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HUX90_08485	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HUX90_08495	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
HUX90_08505	COG0456	acetyltransferase
HUX90_08520	COG1011	Hydrolase
HUX90_08525	COG1349	DNA-binding transcription factor activity
HUX90_08530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUX90_08535	COG2084	Dehydrogenase
HUX90_08540	COG3684	Belongs to the aldolase LacD family
HUX90_08545	COG2942	2-epimerase
HUX90_08550	COG2017	converts alpha-aldose to the beta-anomer
HUX90_08555	COG1501	Belongs to the glycosyl hydrolase 31 family
HUX90_08560	COG2211	Major facilitator Superfamily
HUX90_08565	COG2211	Major facilitator Superfamily
HUX90_08570	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HUX90_08575	COG2271	Major facilitator Superfamily
HUX90_08580	COG1082	Xylose isomerase domain protein TIM barrel
HUX90_08595	COG0174	glutamine synthetase
HUX90_08600	COG3852	Histidine kinase
HUX90_08605	COG2204	response regulator
HUX90_08615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUX90_08630	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUX90_08630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUX90_08635	COG0204	Acyl-transferase
HUX90_08640	COG5339	Protein conserved in bacteria
HUX90_08645	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUX90_08650	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HUX90_08655	COG3084	Protein conserved in bacteria
HUX90_08660	COG0746	molybdenum cofactor guanylyltransferase activity
HUX90_08665	COG1763	Mo-molybdopterin cofactor biosynthetic process
HUX90_08695	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HUX90_08700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HUX90_08705	COG1739	Uncharacterized protein family UPF0029
HUX90_08725	COG0543	2 iron, 2 sulfur cluster binding
HUX90_08730	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HUX90_08735	COG0250	Participates in transcription elongation, termination and antitermination
HUX90_08745	COG0805	protein transport
HUX90_08750	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUX90_08755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUX90_08765	COG3165	ubiquinone biosynthetic process from chorismate
HUX90_08775	COG1322	Protein conserved in bacteria
HUX90_08780	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HUX90_08785	COG0412	Dienelactone hydrolase
HUX90_08795	COG0583	DNA-binding transcription factor activity
HUX90_08800	COG0697	spore germination
HUX90_08805	COG0561	phosphatase activity
HUX90_08810	COG2267	carboxylic ester hydrolase activity
HUX90_08815	COG1280	lysine exporter protein (LysE YggA)
HUX90_08820	COG1280	lysine exporter protein (LysE YggA)
HUX90_08825	COG0514	ATP-dependent DNA helicase (RecQ)
HUX90_08830	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
HUX90_08835	COG2050	protein possibly involved in aromatic compounds catabolism
HUX90_08840	COG2962	Rard protein
HUX90_08865	COG0598	Magnesium transport protein CorA
HUX90_08870	COG3698	Phosphodiester glycosidase
HUX90_08875	COG0210	DNA helicase
HUX90_08880	COG1011	Hydrolase
HUX90_08890	COG3159	Protein conserved in bacteria
HUX90_08900	COG5567	small periplasmic lipoprotein
HUX90_08925	COG3072	Adenylate cyclase
HUX90_08935	COG1587	Uroporphyrinogen-III synthase
HUX90_08940	COG2959	enzyme of heme biosynthesis
HUX90_08945	COG3071	HemY protein
HUX90_08950	COG3119	arylsulfatase activity
HUX90_08955	COG0641	radical SAM
HUX90_08980	COG1113	amino acid transport
HUX90_09000	COG2244	polysaccharide biosynthetic process
HUX90_09005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HUX90_09010	COG0456	acetyltransferase
HUX90_09015	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HUX90_09020	COG1088	dTDP-glucose 4,6-dehydratase activity
HUX90_09025	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HUX90_09030	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HUX90_09035	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HUX90_09040	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUX90_09045	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HUX90_09055	COG3118	belongs to the thioredoxin family
HUX90_09070	COG0210	DNA helicase
HUX90_09075	COG3692	DNA binding
HUX90_09080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUX90_09090	COG0583	DNA-binding transcription factor activity
HUX90_09095	COG3547	Transposase (IS116 IS110 IS902 family)
HUX90_09100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUX90_09110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUX90_09115	COG3978	acetolactate synthase activity
HUX90_09135	COG0606	chelatase, subunit chli
HUX90_09140	COG3085	chromosome segregation
HUX90_09180	COG2186	Transcriptional regulator
HUX90_09185	COG0477	Major facilitator Superfamily
HUX90_09190	COG1609	Transcriptional regulator
HUX90_09195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUX90_09200	COG1879	ABC-type sugar transport system periplasmic component
HUX90_09205	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUX90_09210	COG1129	ABC transporter
HUX90_09240	COG1522	sequence-specific DNA binding
HUX90_09245	COG0716	FMN binding
HUX90_09260	COG3312	ion transport
HUX90_09310	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUX90_09315	COG3539	Fimbrial protein
HUX90_09325	COG3188	usher protein
HUX90_09335	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HUX90_09340	COG0573	inorganic phosphate transmembrane transporter activity
HUX90_09345	COG0581	inorganic phosphate transmembrane transporter activity
HUX90_09350	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUX90_09355	COG0704	Plays a role in the regulation of phosphate uptake
HUX90_09360	COG3711	transcriptional antiterminator
HUX90_09365	COG1263	PTS System
HUX90_09365	COG2190	(PTS) system
HUX90_09365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUX90_09370	COG2723	6-phospho-beta-galactosidase activity
HUX90_09380	COG2382	esterase
HUX90_09385	COG0363	glucosamine-6-phosphate deaminase activity
HUX90_09390	COG3196	Protein conserved in bacteria
HUX90_09400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUX90_09405	COG2252	PERMEase
HUX90_09410	COG0431	NADPH-dependent FMN reductase
HUX90_09415	COG2091	lysine biosynthetic process via aminoadipic acid
HUX90_09430	COG0814	amino acid
HUX90_09480	COG0592	DNA-directed DNA polymerase activity
HUX90_09490	COG0187	DNA topoisomerase II activity
HUX90_09495	COG3753	Protein conserved in bacteria
HUX90_09500	COG0561	phosphatase activity
HUX90_09510	COG2186	Transcriptional regulator
HUX90_09515	COG3734	2-keto-3-deoxy-galactonokinase
HUX90_09520	COG0800	Aldolase
HUX90_09530	COG2271	Major facilitator Superfamily
HUX90_09540	COG0823	Involved in the tonB-independent uptake of proteins
HUX90_09545	COG5645	(Lipo)protein
HUX90_09565	COG2188	Transcriptional regulator
HUX90_09585	COG2207	Transcriptional regulator
HUX90_09590	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUX90_09595	COG3119	arylsulfatase activity
HUX90_09605	COG2149	membrane
HUX90_09615	COG0641	radical SAM
HUX90_09620	COG2814	Major facilitator Superfamily
HUX90_09635	COG0028	Belongs to the TPP enzyme family
HUX90_09640	COG0440	acetolactate synthase activity
HUX90_09645	COG2197	response regulator
HUX90_09650	COG3851	Histidine kinase
HUX90_09655	COG2271	Major facilitator Superfamily
HUX90_09660	COG2271	Major facilitator Superfamily
HUX90_09670	COG2252	PERMEase
HUX90_09690	COG1464	Belongs to the NlpA lipoprotein family
HUX90_09695	COG0697	spore germination
HUX90_09700	COG2814	Major facilitator Superfamily
HUX90_09715	COG2211	Major facilitator Superfamily
HUX90_09720	COG1501	Belongs to the glycosyl hydrolase 31 family
HUX90_09725	COG2982	Protein involved in outer membrane biogenesis
HUX90_09730	COG2233	PERMEase
HUX90_09735	COG0786	glutamate:sodium symporter activity
HUX90_09745	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HUX90_09750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUX90_09755	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUX90_09765	COG0194	GDP metabolic process
HUX90_09775	COG2860	membrane
HUX90_09780	COG3645	SOS response
HUX90_09785	COG1561	YicC-like family, N-terminal region
HUX90_09810	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HUX90_09840	COG1519	Transferase
HUX90_09845	COG0859	PFAM glycosyl transferase family 9
HUX90_09850	COG0438	transferase activity, transferring glycosyl groups
HUX90_09855	COG0515	serine threonine protein kinase
HUX90_09870	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HUX90_09875	COG1442	glycosyl transferase family 8
HUX90_09880	COG1216	Glycosyl transferase, family 2
HUX90_09885	COG3307	-O-antigen
HUX90_09890	COG0859	PFAM glycosyl transferase family 9
HUX90_09895	COG0859	PFAM glycosyl transferase family 9
HUX90_09905	COG0156	8-amino-7-oxononanoate synthase activity
HUX90_09915	COG1216	Glycosyl transferase, family 2
HUX90_09920	COG2861	carbohydrate metabolic process
HUX90_09925	COG4942	peptidase
HUX90_09935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUX90_09940	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HUX90_09955	COG1045	serine acetyltransferase
HUX90_09960	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HUX90_09970	COG2186	Transcriptional regulator
HUX90_09975	COG1620	l-lactate permease
HUX90_09980	COG5295	Hep Hag repeat protein
HUX90_10010	COG2213	PTS system mannitol-specific
HUX90_10010	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUX90_10020	COG1566	PFAM secretion protein HlyD family protein
HUX90_10030	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HUX90_10035	COG3209	COG3209 Rhs family protein
HUX90_10045	COG1413	lyase activity
HUX90_10055	COG3209	COG3209 Rhs family protein
HUX90_10060	COG0625	glutathione transferase activity
HUX90_10070	COG3276	selenocysteine insertion sequence binding
HUX90_10080	COG1012	belongs to the aldehyde dehydrogenase family
HUX90_10095	COG1566	PFAM secretion protein HlyD family protein
HUX90_10100	COG0583	DNA-binding transcription factor activity
HUX90_10105	COG3713	MltA-interacting MipA family protein
HUX90_10115	COG2211	Major facilitator Superfamily
HUX90_10125	COG0235	Class ii aldolase
HUX90_10130	COG3623	hexulose-6-phosphate isomerase
HUX90_10135	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HUX90_10140	COG1070	Carbohydrate kinase
HUX90_10145	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HUX90_10150	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HUX90_10155	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HUX90_10160	COG2731	YhcH YjgK YiaL family protein
HUX90_10170	COG1414	Transcriptional regulator
HUX90_10175	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUX90_10180	COG3977	Valine--pyruvate aminotransferase
HUX90_10185	COG0366	Alpha amylase catalytic
HUX90_10190	COG2992	FlgJ-related protein
HUX90_10195	COG1609	Transcriptional regulator
HUX90_10195	COG2207	Transcriptional regulator
HUX90_10200	COG4214	carbohydrate transport
HUX90_10205	COG1129	ABC transporter
HUX90_10210	COG4213	ABC transporter substrate-binding protein
HUX90_10220	COG1070	Carbohydrate kinase
HUX90_10225	COG4682	membrane
HUX90_10230	COG4682	membrane
HUX90_10235	COG3274	enterobacterial common antigen metabolic process
HUX90_10260	COG1278	Cold shock
HUX90_10265	COG2944	sequence-specific DNA binding
HUX90_10280	COG2885	chlorophyll binding
HUX90_10285	COG0243	molybdopterin cofactor binding
HUX90_10290	COG0456	acetyltransferase
HUX90_10295	COG2818	Glycosylase
HUX90_10300	COG5571	outer membrane autotransporter
HUX90_10305	COG2223	nitrite transmembrane transporter activity
HUX90_10310	COG2194	sulfuric ester hydrolase activity
HUX90_10325	COG0747	negative chemotaxis
HUX90_10330	COG0601	transmembrane transport
HUX90_10335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUX90_10340	COG0444	Belongs to the ABC transporter superfamily
HUX90_10345	COG4608	Belongs to the ABC transporter superfamily
HUX90_10350	COG0814	amino acid
HUX90_10370	COG2194	sulfuric ester hydrolase activity
HUX90_10395	COG1215	transferase activity, transferring glycosyl groups
HUX90_10400	COG1215	transferase activity, transferring glycosyl groups
HUX90_10405	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HUX90_10410	COG0457	Tetratricopeptide repeat
HUX90_10410	COG3118	belongs to the thioredoxin family
HUX90_10415	COG2200	EAL domain
HUX90_10415	COG2199	diguanylate cyclase activity
HUX90_10425	COG0612	Peptidase, M16
HUX90_10435	COG2200	EAL domain
HUX90_10440	COG2982	Protein involved in outer membrane biogenesis
HUX90_10445	COG0477	Major facilitator Superfamily
HUX90_10450	COG1295	ribonuclease BN
HUX90_10455	COG0583	DNA-binding transcription factor activity
HUX90_10460	COG2197	response regulator
HUX90_10475	COG0076	glutamate decarboxylase activity
HUX90_10485	COG2207	Transcriptional regulator
HUX90_10490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUX90_10495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUX90_10505	COG2771	luxR family
HUX90_10510	COG3247	response to pH
HUX90_10525	COG1285	pathogenesis
HUX90_10530	COG2197	response regulator
HUX90_10535	COG3065	identical protein binding
HUX90_10555	COG1393	Belongs to the ArsC family
HUX90_10560	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HUX90_10565	COG0640	Transcriptional regulator
HUX90_10575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUX90_10580	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HUX90_10585	COG0339	signal peptide processing
HUX90_10595	COG3104	oligopeptide transport
HUX90_10600	COG0589	response to stress
HUX90_10610	COG0306	phosphate transporter
HUX90_10615	COG2081	HI0933 family
HUX90_10635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUX90_10640	COG1129	ABC transporter
HUX90_10640	COG0842	Transport permease protein
HUX90_10645	COG0842	Transport permease protein
HUX90_10670	COG0444	Belongs to the ABC transporter superfamily
HUX90_10675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUX90_10680	COG0601	transmembrane transport
HUX90_10685	COG0747	negative chemotaxis
HUX90_10690	COG2091	lysine biosynthetic process via aminoadipic acid
HUX90_10695	COG0628	permease
HUX90_10710	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HUX90_10725	COG3714	YhhN family
HUX90_10735	COG3776	membrane
HUX90_10740	COG0742	ribosomal rna small subunit methyltransferase
HUX90_10745	COG0552	protein localization to endoplasmic reticulum
HUX90_10750	COG2884	Cell division ATP-binding protein ftsE
HUX90_10755	COG2177	Part of the ABC transporter FtsEX involved in
HUX90_10760	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUX90_10765	COG0683	leucine binding
HUX90_10780	COG0456	acetyltransferase
HUX90_10785	COG0683	leucine binding
HUX90_10790	COG0559	Belongs to the binding-protein-dependent transport system permease family
HUX90_10795	COG4177	L-phenylalanine transmembrane transporter activity
HUX90_10800	COG0411	ABC transporter
HUX90_10805	COG0410	ABC transporter
HUX90_10810	COG1653	transport
HUX90_10815	COG1175	transmembrane transport
HUX90_10825	COG3842	ATPase activity
HUX90_10830	COG0584	glycerophosphoryl diester phosphodiesterase
HUX90_10840	COG0405	Gamma-glutamyltransferase
HUX90_10860	COG3157	Type VI secretion system effector, Hcp
HUX90_10865	COG1247	-acetyltransferase
HUX90_10870	COG0673	inositol 2-dehydrogenase activity
HUX90_10875	COG1741	Belongs to the pirin family
HUX90_10880	COG1609	Transcriptional regulator
HUX90_10885	COG3265	gluconokinase activity
HUX90_10890	COG2610	gluconate transmembrane transporter activity
HUX90_10895	COG2095	MarC family integral membrane protein
HUX90_10900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HUX90_10925	COG0058	SHG alpha-glucan phosphorylase activity
HUX90_10930	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HUX90_10950	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUX90_10965	COG1349	DNA-binding transcription factor activity
HUX90_10970	COG4650	regulator
HUX90_10975	COG1690	Belongs to the RtcB family
HUX90_10990	COG0058	SHG alpha-glucan phosphorylase activity
HUX90_10995	COG1640	4-alpha-glucanotransferase
HUX90_11000	COG2610	gluconate transmembrane transporter activity
HUX90_11020	COG5464	transposase or invertase
HUX90_11030	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HUX90_11035	COG1918	ferrous iron import across plasma membrane
HUX90_11040	COG2183	response to ionizing radiation
HUX90_11045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUX90_11050	COG0745	RESPONSE REGULATOR receiver
HUX90_11055	COG2205	protein histidine kinase activity
HUX90_11075	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HUX90_11085	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HUX90_11090	COG1011	Hydrolase
HUX90_11100	COG0494	nUDIX hydrolase
HUX90_11105	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HUX90_11110	COG4972	Pilus assembly protein
HUX90_11115	COG3166	PFAM Fimbrial assembly family protein
HUX90_11130	COG4796	Type ii and iii secretion system protein
HUX90_11145	COG3266	domain, Protein
HUX90_11150	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HUX90_11155	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HUX90_11160	COG0546	phosphoglycolate phosphatase activity
HUX90_11165	COG0180	Tryptophanyl-tRNA synthetase
HUX90_11170	COG2188	Transcriptional regulator
HUX90_11180	COG3457	Alanine racemase
HUX90_11185	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HUX90_11190	COG1735	metal-dependent hydrolase with the TIM-barrel fold
HUX90_11205	COG0626	cystathionine gamma-synthase activity
HUX90_11210	COG2188	Transcriptional regulator
HUX90_11220	COG1082	Xylose isomerase domain protein TIM barrel
HUX90_11225	COG2222	sugar isomerase
HUX90_11230	COG0531	amino acid
HUX90_11245	COG2116	formate transmembrane transporter activity
HUX90_11250	COG2146	nitrite reductase [NAD(P)H] activity
HUX90_11255	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUX90_11265	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUX90_11275	COG2184	nucleotidyltransferase activity
HUX90_11280	COG0512	Glutamine amidotransferase of anthranilate synthase
HUX90_11285	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUX90_11290	COG1289	transmembrane transporter activity
HUX90_11295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUX90_11300	COG1765	OsmC-like protein
HUX90_11305	COG3954	Phosphoribulokinase
HUX90_11315	COG0429	hydrolase of the alpha beta-hydrolase fold
HUX90_11320	COG0488	(ABC) transporter
HUX90_11335	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HUX90_11340	COG1047	Peptidyl-prolyl cis-trans
HUX90_11350	COG0545	Peptidyl-prolyl cis-trans isomerase
HUX90_11355	COG2964	Protein conserved in bacteria
HUX90_11425	COG0089	rRNA binding
HUX90_11515	COG0201	protein transport
HUX90_11555	COG0789	Transcriptional regulator
HUX90_11560	COG3036	rescue of stalled ribosome
HUX90_11570	COG0569	domain protein
HUX90_11590	COG0758	DNA mediated transformation
HUX90_11600	COG0551	DNA topoisomerase type I activity
HUX90_11620	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HUX90_11660	COG1126	abc transporter atp-binding protein
HUX90_11665	COG0765	amino acid transport
HUX90_11670	COG4597	amino acid ABC transporter
HUX90_11675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUX90_11685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUX90_11690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUX90_11695	COG1309	transcriptional regulator
HUX90_11705	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HUX90_11715	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HUX90_11725	COG4145	pantothenate transmembrane transporter activity
HUX90_11730	COG3924	membrane
HUX90_11735	COG0439	Biotin carboxylase
HUX90_11740	COG0511	ligase activity, forming carbon-carbon bonds
HUX90_11745	COG0604	alcohol dehydrogenase
HUX90_11750	COG2199	diguanylate cyclase activity
HUX90_11750	COG2200	EAL domain
HUX90_11755	COG1077	Cell shape determining protein MreB Mrl
HUX90_11760	COG1792	Involved in formation and maintenance of cell shape
HUX90_11765	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HUX90_11775	COG1530	ribonuclease E activity
HUX90_11780	COG3164	Protein of unknown function
HUX90_11785	COG0312	modulator of DNA gyrase
HUX90_11790	COG0583	DNA-binding transcription factor activity
HUX90_11810	COG2732	(Barnase) inhibitor
HUX90_11830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUX90_11835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUX90_11840	COG3105	Protein conserved in bacteria
HUX90_11845	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HUX90_11860	COG0625	glutathione transferase activity
HUX90_11865	COG2969	positive regulation of protein catabolic process
HUX90_11870	COG3069	C4-dicarboxylate transmembrane transporter activity
HUX90_11900	COG2731	YhcH YjgK YiaL family protein
HUX90_11905	COG4804	nuclease activity
HUX90_11910	COG0493	'glutamate synthase
HUX90_11915	COG0067	glutamate synthase
HUX90_11915	COG0069	glutamate synthase activity
HUX90_11915	COG0070	glutamate synthase
HUX90_11920	COG1242	4 iron, 4 sulfur cluster binding
HUX90_11925	COG5002	protein histidine kinase activity
HUX90_11925	COG0784	Response regulator, receiver
HUX90_11925	COG2198	Histidine kinase
HUX90_11930	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HUX90_11940	COG0515	serine threonine protein kinase
HUX90_11945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUX90_11960	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HUX90_11965	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HUX90_11970	COG1137	ATPase activity
HUX90_11975	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HUX90_11980	COG3117	lipopolysaccharide transmembrane transporter activity
HUX90_11985	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HUX90_11990	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HUX90_11990	COG0517	IMP dehydrogenase activity
HUX90_11995	COG0530	calcium, potassium:sodium antiporter activity
HUX90_12000	COG1127	ABC transporter
HUX90_12005	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUX90_12010	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HUX90_12015	COG2854	intermembrane phospholipid transfer
HUX90_12025	COG5007	Belongs to the BolA IbaG family
HUX90_12035	COG3423	Transcriptional regulator
HUX90_12040	COG0142	geranyltranstransferase activity
HUX90_12055	COG0697	spore germination
HUX90_12065	COG2027	D-alanyl-D-alanine carboxypeptidase
HUX90_12070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUX90_12075	COG1534	Rna-binding protein
HUX90_12085	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUX90_12090	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HUX90_12100	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HUX90_12110	COG2194	sulfuric ester hydrolase activity
HUX90_12130	COG0195	Participates in both transcription termination and antitermination
HUX90_12170	COG0513	Belongs to the DEAD box helicase family
HUX90_12175	COG0814	amino acid
HUX90_12180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUX90_12185	COG0826	peptidase U32
HUX90_12190	COG0826	peptidase U32
HUX90_12195	COG3154	lipid carrier protein
HUX90_12200	COG3153	acetyltransferase
HUX90_12215	COG0693	protein deglycase activity
HUX90_12220	COG0702	epimerase
HUX90_12225	COG0701	Predicted permease
HUX90_12230	COG2823	Periplasmic or secreted lipoprotein
HUX90_12250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HUX90_12255	COG3539	Fimbrial protein
HUX90_12260	COG3188	usher protein
HUX90_12265	COG3121	Chaperone
HUX90_12270	COG3539	Fimbrial protein
HUX90_12275	COG0363	glucosamine-6-phosphate deaminase activity
HUX90_12280	COG3716	PTS system mannose fructose sorbose family IID component
HUX90_12285	COG3715	PTS system
HUX90_12290	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUX90_12300	COG2222	sugar isomerase
HUX90_12305	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HUX90_12310	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUX90_12315	COG3716	PTS system mannose fructose sorbose family IID component
HUX90_12325	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUX90_12335	COG1349	DNA-binding transcription factor activity
HUX90_12345	COG2002	toxin-antitoxin pair type II binding
HUX90_12350	COG2721	sulfolactate sulfo-lyase activity
HUX90_12355	COG2271	Major facilitator Superfamily
HUX90_12365	COG2084	Dehydrogenase
HUX90_12370	COG1929	Belongs to the glycerate kinase type-1 family
HUX90_12395	COG0583	DNA-binding transcription factor activity
HUX90_12400	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUX90_12410	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HUX90_12415	COG1882	Formate acetyltransferase
HUX90_12420	COG0251	oxidation-reduction process
HUX90_12425	COG1760	l-serine dehydratase
HUX90_12430	COG0814	amino acid
HUX90_12445	COG1741	Belongs to the pirin family
HUX90_12450	COG0583	DNA-binding transcription factor activity
HUX90_12455	COG3152	Membrane
HUX90_12460	COG3152	Membrane
HUX90_12465	COG0435	Glutathione S-transferase
HUX90_12470	COG2259	Doxx family
HUX90_12480	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HUX90_12485	COG4575	ribosome binding
HUX90_12490	COG1422	Protein of unknown function (DUF1090)
HUX90_12500	COG0586	Pfam SNARE associated Golgi protein
HUX90_12505	COG2186	Transcriptional regulator
HUX90_12530	COG2271	Major facilitator Superfamily
HUX90_12540	COG2721	sulfolactate sulfo-lyase activity
HUX90_12550	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HUX90_12555	COG0861	Integral membrane protein TerC family
HUX90_12560	COG0673	inositol 2-dehydrogenase activity
HUX90_12565	COG2949	membrane
HUX90_12570	COG1451	nucleotide metabolic process
HUX90_12585	COG5499	transcription regulator containing HTH domain
HUX90_12590	COG1902	pentaerythritol trinitrate reductase activity
HUX90_12590	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUX90_12595	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HUX90_12595	COG3408	Glycogen debranching enzyme
HUX90_12605	COG0531	amino acid
HUX90_12610	COG2731	YhcH YjgK YiaL family protein
HUX90_12615	COG3250	beta-galactosidase activity
HUX90_12620	COG1609	Transcriptional regulator
HUX90_12625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUX90_12635	COG0840	transmembrane signaling receptor activity
HUX90_12640	COG1695	Transcriptional regulator
HUX90_12645	COG2375	cellular response to nickel ion
HUX90_12660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUX90_12665	COG0358	DNA primase activity
HUX90_12670	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HUX90_12680	COG0471	metal ion transport
HUX90_12685	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HUX90_12690	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HUX90_12695	COG0583	DNA-binding transcription factor activity
HUX90_12705	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HUX90_12720	COG4991	sh3 domain protein
HUX90_12725	COG3025	triphosphatase activity
HUX90_12750	COG2268	Band 7 protein
HUX90_12755	COG1585	Membrane protein implicated in regulation of membrane protease activity
HUX90_12765	COG3539	Fimbrial protein
HUX90_12770	COG3121	Chaperone
HUX90_12775	COG3188	usher protein
HUX90_12780	COG3539	Fimbrial protein
HUX90_12785	COG2960	long-chain fatty acid transporting porin activity
HUX90_12805	COG3384	dioxygenase
HUX90_12810	COG0754	glutathionylspermidine amidase activity
HUX90_12820	COG1538	Outer membrane efflux protein
HUX90_12825	COG0494	nUDIX hydrolase
HUX90_12830	COG3151	Protein conserved in bacteria
HUX90_12835	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HUX90_12840	COG3150	esterase
HUX90_12845	COG0187	DNA topoisomerase II activity
HUX90_12865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUX90_12885	COG2211	Major facilitator Superfamily
HUX90_12890	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HUX90_12895	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUX90_12905	COG0642	Histidine kinase
HUX90_12910	COG0745	RESPONSE REGULATOR receiver
HUX90_12915	COG3111	PFAM Bacterial OB fold (BOF) protein
HUX90_12920	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HUX90_12925	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUX90_12930	COG0204	Acyl-transferase
HUX90_12935	COG2132	Multicopper oxidase
HUX90_12940	COG1032	radical SAM domain protein
HUX90_12945	COG4238	major outer membrane lipoprotein
HUX90_12955	COG0656	L-ascorbic acid biosynthetic process
HUX90_12960	COG1979	alcohol dehydrogenase
HUX90_12965	COG2207	Transcriptional regulator
HUX90_12970	COG0586	Pfam SNARE associated Golgi protein
HUX90_12975	COG0626	cystathionine gamma-synthase activity
HUX90_12980	COG0811	peptide transport
HUX90_12985	COG0848	biopolymer transport protein
HUX90_12990	COG1028	Short-chain dehydrogenase reductase Sdr
HUX90_13000	COG0667	Aldo Keto reductase
HUX90_13015	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HUX90_13020	COG0437	4 iron, 4 sulfur cluster binding
HUX90_13025	COG5557	Pfam Polysulphide reductase, NrfD
HUX90_13030	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HUX90_13035	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HUX90_13040	COG1773	rubredoxin
HUX90_13045	COG0375	protein maturation
HUX90_13050	COG0298	carbon dioxide binding
HUX90_13055	COG3547	Transposase (IS116 IS110 IS902 family)
HUX90_13060	COG0625	glutathione transferase activity
HUX90_13065	COG0754	glutathionylspermidine amidase activity
HUX90_13070	COG0306	phosphate transporter
HUX90_13075	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HUX90_13080	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HUX90_13085	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HUX90_13090	COG2244	polysaccharide biosynthetic process
HUX90_13100	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HUX90_13115	COG0156	8-amino-7-oxononanoate synthase activity
HUX90_13120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUX90_13130	COG0318	PFAM AMP-dependent synthetase and ligase
HUX90_13135	COG0456	acetyltransferase
HUX90_13140	COG2186	Transcriptional regulator
HUX90_13145	COG0277	FAD linked oxidase domain protein
HUX90_13150	COG0277	FAD linked oxidase domain protein
HUX90_13155	COG0247	lactate metabolic process
HUX90_13160	COG3193	protein, possibly involved in utilization of glycolate and propanediol
HUX90_13165	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HUX90_13170	COG1620	l-lactate permease
HUX90_13175	COG3064	Membrane
HUX90_13200	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HUX90_13205	COG1459	type II secretion system
HUX90_13210	COG2165	general secretion pathway protein
HUX90_13225	COG4795	General secretion pathway protein
HUX90_13240	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HUX90_13250	COG1811	Na channel or pump
HUX90_13255	COG1982	Orn Lys Arg decarboxylase major
HUX90_13260	COG2211	Major facilitator Superfamily
HUX90_13275	COG1194	a g-specific adenine glycosylase
HUX90_13285	COG3171	Protein conserved in bacteria
HUX90_13295	COG0252	asparaginase activity
HUX90_13305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUX90_13320	COG0762	integral membrane protein
HUX90_13325	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HUX90_13330	COG2805	Type II/IV secretion system protein
HUX90_13335	COG3547	Transposase (IS116 IS110 IS902 family)
HUX90_13350	COG0189	ligase activity
HUX90_13355	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HUX90_13360	COG2356	endonuclease I
HUX90_13370	COG2814	Major facilitator Superfamily
HUX90_13390	COG1166	arginine decarboxylase activity
HUX90_13405	COG0501	Belongs to the peptidase M48B family
HUX90_13410	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HUX90_13415	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUX90_13420	COG2213	PTS system mannitol-specific
HUX90_13425	COG1063	alcohol dehydrogenase
HUX90_13430	COG1494	fructose-1,6-bisphosphatase
HUX90_13440	COG1072	(Pantothenic acid kinase))
HUX90_13445	COG1122	ATPase activity
HUX90_13450	COG1122	ATPase activity
HUX90_13480	COG0191	fructose-bisphosphate aldolase activity
HUX90_13485	COG0668	transmembrane transport
HUX90_13495	COG2968	Membrane
HUX90_13500	COG0583	DNA-binding transcription factor activity
HUX90_13505	COG0427	acetyl-CoA hydrolase
HUX90_13510	COG1024	Enoyl-CoA hydratase
HUX90_13515	COG1703	isobutyryl-CoA mutase activity
HUX90_13520	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUX90_13520	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUX90_13540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUX90_13555	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HUX90_13575	COG0006	proline dipeptidase activity
HUX90_13580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUX90_13585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUX90_13610	COG1028	Short-chain dehydrogenase reductase Sdr
HUX90_13615	COG2723	6-phospho-beta-galactosidase activity
HUX90_13625	COG1272	protein, Hemolysin III
HUX90_13635	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HUX90_13645	COG0716	FMN binding
HUX90_13650	COG4974	Belongs to the 'phage' integrase family
HUX90_13655	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUX90_13660	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HUX90_13690	COG2233	PERMEase
HUX90_13700	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUX90_13705	COG2252	PERMEase
HUX90_13710	COG0402	S-adenosylhomocysteine deaminase activity
HUX90_13715	COG2233	PERMEase
HUX90_13720	COG2080	2 iron, 2 sulfur cluster binding
HUX90_13720	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUX90_13725	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUX90_13730	COG0402	S-adenosylhomocysteine deaminase activity
HUX90_13735	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUX90_13735	COG0493	'glutamate synthase
HUX90_13740	COG2068	MobA-Related Protein
HUX90_13745	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HUX90_13750	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HUX90_13750	COG3608	succinylglutamate desuccinylase aspartoacylase
HUX90_13755	COG0549	Belongs to the carbamate kinase family
HUX90_13765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUX90_13770	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUX90_13775	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUX90_13785	COG2080	2 iron, 2 sulfur cluster binding
HUX90_13790	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUX90_13810	COG3387	PFAM Glycoside hydrolase 15-related
HUX90_13900	COG3710	Transcriptional regulator
HUX90_13900	COG0457	Tetratricopeptide repeat
HUX90_13905	COG0457	Tetratricopeptide repeat
HUX90_13925	COG3710	Transcriptional regulator
HUX90_13930	COG2771	luxR family
HUX90_13935	COG0814	amino acid
HUX90_13940	COG0183	Belongs to the thiolase family
HUX90_13950	COG1028	Short-chain dehydrogenase reductase Sdr
HUX90_13955	COG2814	Major facilitator Superfamily
HUX90_13960	COG1794	racemase activity, acting on amino acids and derivatives
HUX90_13965	COG0583	DNA-binding transcription factor activity
HUX90_13975	COG1609	Transcriptional regulator
HUX90_13990	COG0667	Aldo Keto reductase
HUX90_14000	COG0861	Integral membrane protein TerC family
HUX90_14015	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
HUX90_14030	COG2165	general secretion pathway protein
HUX90_14035	COG4795	General secretion pathway protein
HUX90_14045	COG4967	type IV pilus modification protein PilV
HUX90_14050	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HUX90_14055	COG1025	Belongs to the peptidase M16 family
HUX90_14060	COG1074	ATP-dependent DNA helicase activity
HUX90_14065	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUX90_14070	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HUX90_14070	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HUX90_14075	COG0860	N-Acetylmuramoyl-L-alanine amidase
HUX90_14095	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HUX90_14100	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HUX90_14105	COG2166	iron-sulfur cluster assembly
HUX90_14110	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUX90_14120	COG0583	DNA-binding transcription factor activity
HUX90_14125	COG2363	Small membrane protein
HUX90_14135	COG1349	DNA-binding transcription factor activity
HUX90_14145	COG1070	Carbohydrate kinase
HUX90_14155	COG0738	Major facilitator superfamily
HUX90_14160	COG0235	Class ii aldolase
HUX90_14165	COG1454	alcohol dehydrogenase
HUX90_14175	COG1760	l-serine dehydratase
HUX90_14180	COG0814	amino acid
HUX90_14185	COG1611	Belongs to the LOG family
HUX90_14200	COG3098	single-species biofilm formation
HUX90_14205	COG0564	pseudouridine synthase activity
HUX90_14210	COG0716	FMN binding
HUX90_14215	COG2271	Major facilitator Superfamily
HUX90_14220	COG4948	Mandelate Racemase Muconate Lactonizing
HUX90_14225	COG4948	Mandelate Racemase Muconate Lactonizing
HUX90_14230	COG4999	Histidine kinase
HUX90_14230	COG3850	Histidine kinase
HUX90_14230	COG2205	protein histidine kinase activity
HUX90_14230	COG3437	response regulator, receiver
HUX90_14240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUX90_14245	COG2336	PFAM SpoVT AbrB
HUX90_14250	COG2337	Toxic component of a toxin-antitoxin (TA) module
HUX90_14255	COG3956	TIGRFAM MazG family protein
HUX90_14275	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HUX90_14285	COG0602	queuosine metabolic process
HUX90_14290	COG1070	Carbohydrate kinase
HUX90_14295	COG0720	synthase
HUX90_14320	COG1203	CRISPR-associated helicase, Cas3
HUX90_14335	COG1857	crispr-associated protein
HUX90_14350	COG1518	maintenance of DNA repeat elements
HUX90_14355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUX90_14360	COG2234	aminopeptidase activity
HUX90_14415	COG1388	LysM domain
HUX90_14415	COG4942	peptidase
HUX90_14420	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUX90_14435	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HUX90_14445	COG2610	gluconate transmembrane transporter activity
HUX90_14450	COG3622	Belongs to the hyi family
HUX90_14455	COG0235	Class ii aldolase
HUX90_14460	COG3395	kinase activity
HUX90_14465	COG2084	Dehydrogenase
HUX90_14470	COG1349	DNA-binding transcription factor activity
HUX90_14475	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUX90_14495	COG3604	Transcriptional regulator
HUX90_14500	COG0309	Hydrogenase expression formation protein (HypE)
HUX90_14505	COG0409	Hydrogenase expression formation protein
HUX90_14510	COG0298	carbon dioxide binding
HUX90_14515	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HUX90_14520	COG0375	protein maturation
HUX90_14530	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUX90_14535	COG0651	ATP synthesis coupled electron transport
HUX90_14540	COG0650	Formate hydrogenlyase subunit 4
HUX90_14545	COG3261	NADH dehydrogenase
HUX90_14545	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HUX90_14550	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUX90_14555	COG3260	NADH ubiquinone oxidoreductase 20
HUX90_14565	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HUX90_14570	COG2723	6-phospho-beta-galactosidase activity
HUX90_14575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUX90_14575	COG1263	PTS System
HUX90_14580	COG1609	Transcriptional regulator
HUX90_14585	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUX90_14590	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HUX90_14615	COG1349	DNA-binding transcription factor activity
HUX90_14620	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUX90_14625	COG1028	Short-chain dehydrogenase reductase Sdr
HUX90_14635	COG3732	PTS system glucitol sorbitol-specific
HUX90_14640	COG3730	PTS system glucitol sorbitol-specific
HUX90_14645	COG2951	lytic endotransglycosylase activity
HUX90_14650	COG1546	Belongs to the CinA family
HUX90_14670	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HUX90_14700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUX90_14705	COG1238	metal cluster binding
HUX90_14720	COG2814	Major facilitator Superfamily
HUX90_14725	COG1566	PFAM secretion protein HlyD family protein
HUX90_14730	COG1846	Transcriptional regulator
HUX90_14740	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HUX90_14745	COG2814	Major facilitator Superfamily
HUX90_14750	COG2113	Glycine betaine
HUX90_14755	COG4176	ABC-type proline glycine betaine transport system permease component
HUX90_14760	COG4175	Glycine betaine
HUX90_14765	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUX90_14770	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUX90_14780	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HUX90_14785	COG4575	ribosome binding
HUX90_14800	COG2916	Histone family protein nucleoid-structuring protein H-NS
HUX90_14805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUX90_14810	COG0640	Transcriptional regulator
HUX90_14815	COG0401	homolog of Blt101
HUX90_14820	COG1652	LysM domain
HUX90_14825	COG1802	Transcriptional regulator
HUX90_14830	COG1113	amino acid transport
HUX90_14835	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HUX90_14840	COG1012	belongs to the aldehyde dehydrogenase family
HUX90_14845	COG0579	oxidoreductase
HUX90_14895	COG3311	Transcriptional regulator
HUX90_14945	COG0582	viral genome integration into host DNA
HUX90_14960	COG2867	negative regulation of translational initiation
HUX90_14970	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUX90_14975	COG0497	DNA recombination
HUX90_14990	COG4536	flavin adenine dinucleotide binding
HUX90_14995	COG4137	Cytochrome C assembly protein
HUX90_15000	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HUX90_15025	COG2885	chlorophyll binding
HUX90_15030	COG2199	diguanylate cyclase activity
HUX90_15045	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HUX90_15050	COG0287	Prephenate dehydrogenase
HUX90_15050	COG1605	Chorismate mutase
HUX90_15055	COG1605	Chorismate mutase
HUX90_15055	COG0077	Prephenate dehydratase
HUX90_15065	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HUX90_15070	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUX90_15075	COG0564	pseudouridine synthase activity
HUX90_15085	COG0542	response to heat
HUX90_15110	COG0477	Major facilitator Superfamily
HUX90_15115	COG5544	Lipoprotein
HUX90_15120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUX90_15125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUX90_15125	COG0045	succinate-CoA ligase (ADP-forming) activity
HUX90_15125	COG1042	CoA-binding domain protein
HUX90_15135	COG3118	belongs to the thioredoxin family
HUX90_15140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUX90_15160	COG0583	DNA-binding transcription factor activity
HUX90_15165	COG0513	Belongs to the DEAD box helicase family
HUX90_15175	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HUX90_15185	COG1595	DNA-templated transcription, initiation
HUX90_15190	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HUX90_15195	COG3026	antisigma factor binding
HUX90_15200	COG3086	response to oxidative stress
HUX90_15210	COG0681	Belongs to the peptidase S26 family
HUX90_15230	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HUX90_15245	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUX90_15250	COG1737	Transcriptional regulator
HUX90_15255	COG0560	Phosphoserine phosphatase
HUX90_15275	COG2205	protein histidine kinase activity
HUX90_15280	COG3170	Tfp pilus assembly protein FimV
HUX90_15285	COG2204	response regulator
HUX90_15290	COG0347	Belongs to the P(II) protein family
HUX90_15295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUX90_15295	COG1017	nitric oxide dioxygenase activity
HUX90_15305	COG1940	carbohydrate kinase activity
HUX90_15310	COG0457	Tetratricopeptide repeat
HUX90_15315	COG1879	ABC-type sugar transport system periplasmic component
HUX90_15320	COG1129	ABC transporter
HUX90_15325	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUX90_15330	COG1063	alcohol dehydrogenase
HUX90_15335	COG2017	converts alpha-aldose to the beta-anomer
HUX90_15340	COG2259	Doxx family
HUX90_15365	COG4638	Rieske (2fe-2S)
HUX90_15370	COG0583	DNA-binding transcription factor activity
HUX90_15375	COG2814	Major facilitator Superfamily
HUX90_15380	COG3711	transcriptional antiterminator
HUX90_15385	COG1073	alpha beta
HUX90_15390	COG0483	inositol monophosphate 1-phosphatase activity
HUX90_15410	COG0822	iron-sulfur transferase activity
HUX90_15430	COG0633	Ferredoxin
HUX90_15435	COG2975	iron-sulfur cluster assembly
HUX90_15450	COG2897	thiosulfate sulfurtransferase activity
HUX90_15455	COG2373	Large extracellular alpha-helical protein
HUX90_15460	COG4953	penicillin-binding protein 1C
HUX90_15490	COG2976	Protein conserved in bacteria
HUX90_15505	COG1645	bacterial-type flagellum-dependent swarming motility
HUX90_15515	COG0517	IMP dehydrogenase activity
HUX90_15515	COG0516	GMP reductase activity
HUX90_15525	COG0582	viral genome integration into host DNA
HUX90_15570	COG3846	protein secretion by the type IV secretion system
HUX90_15640	COG3133	Outer membrane lipoprotein
HUX90_15655	COG2200	EAL domain
HUX90_15660	COG0248	Ppx GppA phosphatase
HUX90_15665	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HUX90_15670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HUX90_15685	COG2233	PERMEase
HUX90_15695	COG1393	Belongs to the ArsC family
HUX90_15700	COG4783	chaperone-mediated protein folding
HUX90_15705	COG0628	permease
HUX90_15730	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUX90_15735	COG3261	NADH dehydrogenase
HUX90_15735	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HUX90_15740	COG0651	ATP synthesis coupled electron transport
HUX90_15745	COG4237	Hydrogenase 4 membrane
HUX90_15755	COG0650	Formate hydrogenlyase subunit 4
HUX90_15760	COG0651	ATP synthesis coupled electron transport
HUX90_15765	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUX90_15770	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HUX90_15775	COG2716	regulation of RNA biosynthetic process
HUX90_15785	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HUX90_15805	COG2321	neutral zinc metallopeptidase
HUX90_15815	COG0400	carboxylic ester hydrolase activity
HUX90_15830	COG1393	Belongs to the ArsC family
HUX90_15840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUX90_15845	COG3850	Histidine kinase
HUX90_15850	COG0493	'glutamate synthase
HUX90_15850	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUX90_15860	COG5342	invasion associated locus B
HUX90_15865	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HUX90_15870	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUX90_15875	COG0280	phosphate acetyltransferase
HUX90_15875	COG0281	malic enzyme
HUX90_15880	COG4810	utilization protein
HUX90_15885	COG4917	ethanolamine utilization protein
HUX90_15890	COG4766	ethanolamine catabolic process
HUX90_15895	COG4812	Cobalamin adenosyltransferase
HUX90_15900	COG0280	phosphate acetyltransferase
HUX90_15905	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HUX90_15910	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
HUX90_15915	COG1012	belongs to the aldehyde dehydrogenase family
HUX90_15920	COG4820	ethanolamine utilization protein (EutJ)
HUX90_15925	COG1454	alcohol dehydrogenase
HUX90_15930	COG3192	ethanolamine utilization protein
HUX90_15935	COG4819	ethanolamine utilization protein
HUX90_15940	COG4303	Ethanolamine ammonia lyase large subunit
HUX90_15950	COG4816	utilization protein
HUX90_15955	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HUX90_15960	COG2207	Transcriptional regulator
HUX90_15970	COG0860	N-Acetylmuramoyl-L-alanine amidase
HUX90_15990	COG2837	iron assimilation
HUX90_15995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUX90_16000	COG1263	PTS System
HUX90_16000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUX90_16015	COG1028	Short-chain dehydrogenase reductase Sdr
HUX90_16020	COG4150	thiosulfate binding
HUX90_16025	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HUX90_16030	COG4208	sulfate ABC transporter
HUX90_16035	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HUX90_16040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUX90_16055	COG2190	(PTS) system
HUX90_16060	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUX90_16065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUX90_16070	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUX90_16090	COG3530	Putative quorum-sensing-regulated virulence factor
HUX90_16095	COG0385	Bile acid
HUX90_16100	COG0583	DNA-binding transcription factor activity
HUX90_16110	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HUX90_16115	COG2211	Major facilitator Superfamily
HUX90_16125	COG0583	DNA-binding transcription factor activity
HUX90_16155	COG3415	Transposase
HUX90_16160	COG3415	Transposase
HUX90_16175	COG2200	EAL domain
HUX90_16175	COG2199	diguanylate cyclase activity
HUX90_16180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HUX90_16205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUX90_16210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUX90_16215	COG0006	proline dipeptidase activity
HUX90_16220	COG1363	Peptidase, m42
HUX90_16230	COG2207	Transcriptional regulator
HUX90_16235	COG3279	Response regulator of the LytR AlgR family
HUX90_16240	COG3275	phosphorelay sensor kinase activity
HUX90_16245	COG0436	Aminotransferase
HUX90_16255	COG1560	Kdo2-lipid A biosynthetic process
HUX90_16280	COG0028	Belongs to the TPP enzyme family
HUX90_16285	COG0679	Auxin Efflux Carrier
HUX90_16290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUX90_16295	COG0784	Response regulator, receiver
HUX90_16295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUX90_16295	COG2198	Histidine kinase
HUX90_16295	COG2205	protein histidine kinase activity
HUX90_16300	COG2197	response regulator
HUX90_16305	COG1566	PFAM secretion protein HlyD family protein
HUX90_16310	COG0477	Major facilitator Superfamily
HUX90_16350	COG2116	formate transmembrane transporter activity
HUX90_16355	COG2853	Lipoprotein
HUX90_16365	COG2067	long-chain fatty acid transport protein
HUX90_16370	COG3691	Protein conserved in bacteria
HUX90_16385	COG2062	phosphohistidine phosphatase, SixA
HUX90_16390	COG3539	Fimbrial protein
HUX90_16395	COG3188	usher protein
HUX90_16400	COG3121	Chaperone
HUX90_16405	COG3539	Fimbrial protein
HUX90_16410	COG3539	Fimbrial protein
HUX90_16415	COG3539	Fimbrial protein
HUX90_16445	COG0730	response to heat
HUX90_16450	COG3101	peptidyl-lysine hydroxylation
HUX90_16465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUX90_16470	COG2814	Major facilitator Superfamily
HUX90_16485	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HUX90_16495	COG0586	Pfam SNARE associated Golgi protein
HUX90_16505	COG0285	dihydrofolate synthase activity
HUX90_16510	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HUX90_16515	COG1286	toxin biosynthetic process
HUX90_16520	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HUX90_16525	COG0163	prenyltransferase activity
HUX90_16530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUX90_16535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUX90_16540	COG4215	(ABC) transporter
HUX90_16545	COG4160	amino acid transport
HUX90_16550	COG4598	ABC transporter
HUX90_16555	COG5464	transposase or invertase
HUX90_16560	COG1090	epimerase
HUX90_16565	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HUX90_16570	COG0625	glutathione transferase activity
HUX90_16575	COG0625	glutathione transferase activity
HUX90_16585	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HUX90_16590	COG1288	antiporter activity
HUX90_16595	COG0857	belongs to the CobB CobQ family
HUX90_16595	COG0280	phosphate acetyltransferase
HUX90_16600	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HUX90_16615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUX90_16620	COG0490	domain, Protein
HUX90_16620	COG0471	metal ion transport
HUX90_16630	COG0436	Aminotransferase
HUX90_16635	COG0583	DNA-binding transcription factor activity
HUX90_16655	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HUX90_16660	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HUX90_16665	COG1034	ATP synthesis coupled electron transport
HUX90_16680	COG0839	Belongs to the complex I subunit 6 family
HUX90_16690	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUX90_16695	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUX90_16725	COG2153	protein acetylation
HUX90_16730	COG4575	ribosome binding
HUX90_16735	COG1169	isochorismate synthase
HUX90_16750	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HUX90_16760	COG0318	PFAM AMP-dependent synthetase and ligase
HUX90_16830	COG5464	transposase or invertase
HUX90_16835	COG0247	lactate metabolic process
HUX90_16845	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUX90_16850	COG2271	Major facilitator Superfamily
HUX90_16855	COG0584	glycerophosphoryl diester phosphodiesterase
HUX90_16865	COG3642	lipopolysaccharide core region biosynthetic process
HUX90_16870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUX90_16875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUX90_16880	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUX90_16885	COG3468	outer membrane autotransporter barrel domain protein
HUX90_16895	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUX90_16900	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
HUX90_16905	COG3234	Protein of unknown function (DUF1175)
HUX90_16910	COG2373	Large extracellular alpha-helical protein
HUX90_16915	COG5445	Predicted secreted protein (DUF2300)
HUX90_16920	COG4676	Protein conserved in bacteria
HUX90_16925	COG2205	protein histidine kinase activity
HUX90_16925	COG0784	Response regulator, receiver
HUX90_16930	COG2197	response regulator
HUX90_16935	COG2198	Histidine kinase
HUX90_16935	COG0642	Histidine kinase
HUX90_16945	COG1477	protein flavinylation
HUX90_16950	COG2169	Transcriptional regulator
HUX90_16950	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUX90_16960	COG4615	Cyclic peptide transporter
HUX90_16980	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUX90_16980	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUX90_16985	COG3062	negative regulation of establishment of protein localization
HUX90_16995	COG0437	4 iron, 4 sulfur cluster binding
HUX90_17000	COG0348	domain, Protein
HUX90_17005	COG3043	anaerobic respiration
HUX90_17010	COG3005	denitrification pathway
HUX90_17015	COG4133	protoheme IX ABC transporter activity
HUX90_17020	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUX90_17025	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUX90_17030	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUX90_17040	COG1138	Cytochrome C-type biogenesis protein
HUX90_17045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUX90_17050	COG3088	subunit of a heme lyase
HUX90_17050	COG4235	cytochrome complex assembly
HUX90_17055	COG2197	response regulator
HUX90_17070	COG3083	sulfuric ester hydrolase activity
HUX90_17090	COG1061	Type III restriction enzyme res subunit
HUX90_17095	COG1187	pseudouridine synthase activity
HUX90_17100	COG2814	Major facilitator Superfamily
HUX90_17110	COG4172	Belongs to the ABC transporter superfamily
HUX90_17115	COG4239	(ABC) transporter, permease
HUX90_17120	COG4174	ABC transporter (Permease)
HUX90_17125	COG4166	transmembrane transport
HUX90_17130	COG2200	EAL domain
HUX90_17135	COG0791	NLP P60 protein
HUX90_17140	COG0671	phosphoesterase, PA-phosphatase related
HUX90_17145	COG0523	cobalamin synthesis protein
HUX90_17150	COG0246	Mannitol dehydrogenase
HUX90_17165	COG2814	Major facilitator Superfamily
HUX90_17170	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUX90_17170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUX90_17175	COG1105	Belongs to the carbohydrate kinase PfkB family
HUX90_17180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUX90_17180	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HUX90_17180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUX90_17185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUX90_17190	COG2313	pseudouridylate synthase activity
HUX90_17195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HUX90_17200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUX90_17210	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HUX90_17215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUX90_17215	COG1522	sequence-specific DNA binding
HUX90_17225	COG2855	membrane
HUX90_17230	COG0583	DNA-binding transcription factor activity
HUX90_17235	COG0833	amino acid
HUX90_17240	COG4771	TonB-dependent receptor
HUX90_17255	COG2311	Membrane
HUX90_17260	COG1609	Transcriptional regulator
HUX90_17265	COG1879	ABC-type sugar transport system periplasmic component
HUX90_17270	COG1129	ABC transporter
HUX90_17275	COG4211	Belongs to the binding-protein-dependent transport system permease family
HUX90_17280	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HUX90_17280	COG0167	dihydroorotate dehydrogenase activity
HUX90_17285	COG0493	'glutamate synthase
HUX90_17295	COG2949	membrane
HUX90_17305	COG1346	cytolysis
HUX90_17315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HUX90_17330	COG1028	Short-chain dehydrogenase reductase Sdr
HUX90_17335	COG0586	Pfam SNARE associated Golgi protein
HUX90_17345	COG1686	Belongs to the peptidase S11 family
HUX90_17350	COG0277	FAD linked oxidase domain protein
HUX90_17355	COG1472	Belongs to the glycosyl hydrolase 3 family
HUX90_17360	COG1732	Glycine betaine
HUX90_17365	COG1174	glycine betaine transport
HUX90_17370	COG1125	glycine betaine transport
HUX90_17375	COG1174	glycine betaine transport
HUX90_17385	COG0789	Transcriptional regulator
HUX90_17390	COG3275	phosphorelay sensor kinase activity
HUX90_17395	COG3279	Response regulator of the LytR AlgR family
HUX90_17400	COG4807	Protein conserved in bacteria
HUX90_17405	COG4808	Protein conserved in bacteria
HUX90_17410	COG4715	Zinc finger, swim domain protein
HUX90_17415	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HUX90_17420	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HUX90_17425	COG0714	Associated with various cellular activities
HUX90_17435	COG3831	ATPase activity
HUX90_17440	COG3831	ATPase activity
HUX90_17450	COG0489	protein tyrosine kinase activity
HUX90_17460	COG3539	Fimbrial protein
HUX90_17465	COG3121	Chaperone
HUX90_17470	COG3188	usher protein
HUX90_17475	COG3539	Fimbrial protein
HUX90_17480	COG5455	response to cobalt ion
HUX90_17500	COG0351	phosphomethylpyrimidine kinase
HUX90_17505	COG3757	hydrolase, family 25
HUX90_17510	COG2188	Transcriptional regulator
HUX90_17515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUX90_17520	COG1397	ADP-ribosylglycohydrolase
HUX90_17525	COG2211	Major facilitator Superfamily
HUX90_17530	COG1830	Aldolase
HUX90_17545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUX90_17550	COG3414	Phosphotransferase system galactitol-specific IIB component
HUX90_17555	COG3775	system Galactitol-specific IIC component
HUX90_17560	COG1063	alcohol dehydrogenase
HUX90_17590	COG3609	addiction module antidote protein, CC2985 family
HUX90_17600	COG0745	RESPONSE REGULATOR receiver
HUX90_17605	COG2205	protein histidine kinase activity
HUX90_17645	COG4245	von Willebrand factor, type A
HUX90_17650	COG0631	protein serine/threonine phosphatase activity
HUX90_17655	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
HUX90_17660	COG0443	Heat shock 70 kDa protein
HUX90_17665	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HUX90_17670	COG5001	Diguanylate cyclase
HUX90_17670	COG5002	protein histidine kinase activity
HUX90_17670	COG3447	MASE1 domain protein
HUX90_17675	COG0572	uridine kinase
HUX90_17685	COG2982	Protein involved in outer membrane biogenesis
HUX90_17695	COG1596	polysaccharide export
HUX90_17700	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUX90_17705	COG3206	protein involved in exopolysaccharide biosynthesis
HUX90_17705	COG0489	protein tyrosine kinase activity
HUX90_17710	COG0463	Glycosyl transferase, family 2
HUX90_17715	COG1045	serine acetyltransferase
HUX90_17720	COG0438	transferase activity, transferring glycosyl groups
HUX90_17730	COG1216	Glycosyl transferase, family 2
HUX90_17735	COG0110	maltose O-acetyltransferase activity
HUX90_17740	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HUX90_17745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUX90_17750	COG1051	belongs to the nudix hydrolase family
HUX90_17755	COG0297	glycogen (starch) synthase activity
HUX90_17760	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HUX90_17760	COG0662	Cupin 2, conserved barrel domain protein
HUX90_17765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUX90_17770	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HUX90_17780	COG2327	Polysaccharide pyruvyl transferase
HUX90_17785	COG0438	transferase activity, transferring glycosyl groups
HUX90_17795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUX90_17800	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HUX90_17825	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HUX90_17845	COG1215	transferase activity, transferring glycosyl groups
HUX90_17860	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HUX90_17865	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUX90_17890	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HUX90_17895	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HUX90_17895	COG0131	Imidazoleglycerol-phosphate dehydratase
HUX90_17905	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HUX90_17920	COG2161	toxin-antitoxin pair type II binding
HUX90_17925	COG4115	mRNA cleavage
HUX90_17930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUX90_17935	COG0583	DNA-binding transcription factor activity
HUX90_17945	COG0531	amino acid
HUX90_17950	COG2391	methyltransferase activity
HUX90_17955	COG0425	Belongs to the sulfur carrier protein TusA family
HUX90_17960	COG2925	Exonuclease
HUX90_17965	COG1686	Belongs to the peptidase S11 family
HUX90_17975	COG1289	transmembrane transporter activity
HUX90_17980	COG3547	Transposase (IS116 IS110 IS902 family)
HUX90_18030	COG2003	Belongs to the UPF0758 family
HUX90_18075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUX90_18085	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
HUX90_18100	COG1376	ErfK ybiS ycfS ynhG family protein
HUX90_18110	COG0583	DNA-binding transcription factor activity
HUX90_18115	COG0583	DNA-binding transcription factor activity
HUX90_18125	COG0534	Mate efflux family protein
HUX90_18135	COG0217	transcriptional regulatory protein
HUX90_18140	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HUX90_18145	COG0477	Major facilitator Superfamily
HUX90_18175	COG3038	cytochrome b561
HUX90_18180	COG3443	Belongs to the bacterial solute-binding protein 9 family
HUX90_18195	COG2351	hydroxyisourate hydrolase activity
HUX90_18200	COG0745	RESPONSE REGULATOR receiver
HUX90_18205	COG2205	protein histidine kinase activity
HUX90_18220	COG2826	transposase and inactivated derivatives, IS30 family
HUX90_18240	COG1418	mRNA catabolic process
HUX90_18245	COG0270	DNA (cytosine-5-)-methyltransferase activity
HUX90_18250	COG3727	T/G mismatch-specific endonuclease activity
HUX90_18255	COG0697	spore germination
HUX90_18260	COG2354	Protein conserved in bacteria
HUX90_18265	COG5475	Uncharacterized small protein (DUF2158)
HUX90_18270	COG3706	GGDEF domain
HUX90_18290	COG2197	response regulator
HUX90_18295	COG1684	flagellar biosynthetic protein fliR
HUX90_18300	COG1987	bacterial-type flagellum assembly
HUX90_18305	COG1338	Plays a role in the flagellum-specific transport system
HUX90_18310	COG3190	flagellar
HUX90_18315	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HUX90_18320	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HUX90_18325	COG1580	Controls the rotational direction of flagella during chemotaxis
HUX90_18330	COG3144	bacterial-type flagellum assembly
HUX90_18335	COG2882	bacterial-type flagellum organization
HUX90_18340	COG1157	protein secretion by the type III secretion system
HUX90_18345	COG1317	bacterial-type flagellum organization
HUX90_18350	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HUX90_18355	COG1766	The M ring may be actively involved in energy transduction
HUX90_18365	COG2076	Multidrug Resistance protein
HUX90_18370	COG1881	PFAM PEBP family protein
HUX90_18375	COG2207	Transcriptional regulator
HUX90_18390	COG2135	peptidase activity
HUX90_18395	COG0425	Belongs to the sulfur carrier protein TusA family
HUX90_18400	COG2391	methyltransferase activity
HUX90_18410	COG0366	Alpha amylase catalytic
HUX90_18420	COG1516	flagellar protein fliS
HUX90_18425	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HUX90_18430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HUX90_18435	COG1191	sigma factor activity
HUX90_18465	COG2197	response regulator
HUX90_18480	COG2197	response regulator
HUX90_18510	COG3012	SEC-C Motif Domain Protein
HUX90_18510	COG3318	Belongs to the UPF0149 family
HUX90_18515	COG0814	amino acid
HUX90_18525	COG1528	Iron-storage protein
HUX90_18545	COG1528	Iron-storage protein
HUX90_18550	COG1879	ABC-type sugar transport system periplasmic component
HUX90_18555	COG1129	ABC transporter
HUX90_18560	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUX90_18565	COG1877	trehalose-phosphatase activity
HUX90_18575	COG0589	response to stress
HUX90_18590	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HUX90_18595	COG1360	Flagellar Motor Protein
HUX90_18600	COG2198	Histidine kinase
HUX90_18600	COG0643	Histidine kinase
HUX90_18605	COG0835	chemotaxis
HUX90_18610	COG0840	transmembrane signaling receptor activity
HUX90_18615	COG0840	transmembrane signaling receptor activity
HUX90_18620	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HUX90_18625	COG2201	protein-glutamate methylesterase activity
HUX90_18630	COG0745	RESPONSE REGULATOR receiver
HUX90_18635	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HUX90_18640	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HUX90_18645	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HUX90_18655	COG3755	Protein conserved in bacteria
HUX90_18665	COG3102	Protein conserved in bacteria
HUX90_18675	COG3005	denitrification pathway
HUX90_18680	COG0243	molybdopterin cofactor binding
HUX90_18695	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HUX90_18700	COG1801	Protein of unknown function DUF72
HUX90_18705	COG1335	isochorismatase
HUX90_18715	COG0494	nUDIX hydrolase
HUX90_18720	COG0217	transcriptional regulatory protein
HUX90_18750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUX90_18760	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HUX90_18765	COG0739	heme binding
HUX90_18770	COG1560	Kdo2-lipid A biosynthetic process
HUX90_18775	COG0469	pyruvate kinase activity
HUX90_18780	COG1737	Transcriptional regulator
HUX90_18785	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HUX90_18790	COG0129	dihydroxy-acid dehydratase activity
HUX90_18795	COG0800	Aldolase
HUX90_18805	COG3141	response to X-ray
HUX90_18815	COG2979	Protein of unknown function (DUF533)
HUX90_18820	COG1770	oligopeptidase
HUX90_18825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUX90_18830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUX90_18840	COG2372	response to copper ion
HUX90_18845	COG1276	copper resistance
HUX90_18855	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUX90_18875	COG3008	intermembrane lipid transfer
HUX90_18880	COG2995	paraquat-inducible protein a
HUX90_18885	COG1956	GAF domain-containing protein
HUX90_18895	COG0793	Belongs to the peptidase S41A family
HUX90_18905	COG2814	Major facilitator Superfamily
HUX90_18910	COG1414	Transcriptional regulator
HUX90_18940	COG2226	methyltransferase
HUX90_18955	COG3716	PTS system mannose fructose sorbose family IID component
HUX90_18960	COG3715	PTS system
HUX90_18965	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUX90_18965	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUX90_18970	COG1253	flavin adenine dinucleotide binding
HUX90_18975	COG2200	EAL domain
HUX90_18980	COG1760	l-serine dehydratase
HUX90_18990	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUX90_19005	COG0251	oxidation-reduction process
HUX90_19010	COG1199	ATP-dependent helicase activity
HUX90_19015	COG1214	PFAM Peptidase M22, glycoprotease
HUX90_19020	COG3065	identical protein binding
HUX90_19025	COG0318	PFAM AMP-dependent synthetase and ligase
HUX90_19030	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HUX90_19035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUX90_19040	COG4638	Rieske (2fe-2S)
HUX90_19045	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUX90_19050	COG0473	3-isopropylmalate dehydrogenase activity
HUX90_19055	COG0583	DNA-binding transcription factor activity
HUX90_19075	COG2261	transglycosylase associated protein
HUX90_19090	COG2203	Gaf domain
HUX90_19090	COG2199	diguanylate cyclase activity
HUX90_19095	COG3042	response to heat
HUX90_19100	COG3189	MarR family transcriptional regulator
HUX90_19105	COG2807	transmembrane transport
HUX90_19110	COG2207	Transcriptional regulator
HUX90_19125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HUX90_19130	COG2199	diguanylate cyclase activity
HUX90_19135	COG2199	diguanylate cyclase activity
HUX90_19145	COG2766	serine protein kinase
HUX90_19150	COG3713	MltA-interacting MipA family protein
HUX90_19155	COG0656	L-ascorbic acid biosynthetic process
HUX90_19160	COG0676	glucose-6-phosphate 1-epimerase activity
HUX90_19165	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HUX90_19175	COG3139	Protein of unknown function (DUF1315)
HUX90_19180	COG1335	isochorismatase
HUX90_19185	COG0252	asparaginase activity
HUX90_19190	COG0616	signal peptide processing
HUX90_19195	COG0778	Nitroreductase
HUX90_19205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HUX90_19215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUX90_19225	COG0494	nUDIX hydrolase
HUX90_19230	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HUX90_19235	COG2897	thiosulfate sulfurtransferase activity
HUX90_19240	COG4136	ATPase activity
HUX90_19245	COG4135	transport system, permease component
HUX90_19250	COG4134	Bacterial extracellular solute-binding protein
HUX90_19255	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUX90_19260	COG0398	Pfam SNARE associated Golgi protein
HUX90_19270	COG0398	Pfam SNARE associated Golgi protein
HUX90_19275	COG0708	Exodeoxyribonuclease III
HUX90_19305	COG3678	ATP-independent chaperone mediated protein folding
HUX90_19315	COG0322	excinuclease ABC activity
HUX90_19325	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUX90_19330	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUX90_19335	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUX90_19340	COG1447	Phosphotransferase system cellobiose-specific component IIA
HUX90_19345	COG2169	Transcriptional regulator
HUX90_19345	COG1917	Cupin 2, conserved barrel domain protein
HUX90_19350	COG1486	melibiose metabolic process
HUX90_19360	COG0753	catalase activity
HUX90_19385	COG1988	membrane-bound metal-dependent
HUX90_19390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUX90_19400	COG3001	Fructosamine kinase
HUX90_19410	COG1105	Belongs to the carbohydrate kinase PfkB family
HUX90_19415	COG3137	Salt-induced outer membrane protein
HUX90_19475	COG0386	Belongs to the glutathione peroxidase family
HUX90_19485	COG0791	NLP P60 protein
HUX90_19490	COG2200	EAL domain
HUX90_19500	COG4256	Hemin uptake protein
HUX90_19505	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HUX90_19515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUX90_19515	COG0574	Belongs to the PEP-utilizing enzyme family
HUX90_19520	COG0318	PFAM AMP-dependent synthetase and ligase
HUX90_19525	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HUX90_19530	COG0644	oxidoreductase
HUX90_19535	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HUX90_19540	COG2086	electron transfer activity
HUX90_19545	COG1917	Cupin 2, conserved barrel domain protein
HUX90_19545	COG2207	Transcriptional regulator
HUX90_19550	COG1960	acyl-CoA dehydrogenase activity
HUX90_19555	COG4670	ketone body catabolic process
HUX90_19570	COG2271	Major facilitator Superfamily
HUX90_19575	COG0738	Major facilitator superfamily
HUX90_19590	COG0628	permease
HUX90_19595	COG0277	FAD linked oxidase domain protein
HUX90_19595	COG0247	lactate metabolic process
HUX90_19600	COG2050	protein possibly involved in aromatic compounds catabolism
HUX90_19610	COG0316	Belongs to the HesB IscA family
HUX90_19615	COG0719	Fe-S assembly protein
HUX90_19620	COG0396	ATPase activity
HUX90_19625	COG0719	Fe-S assembly protein
HUX90_19640	COG1376	ErfK ybiS ycfS ynhG family protein
HUX90_19645	COG4238	major outer membrane lipoprotein
HUX90_19650	COG0469	pyruvate kinase activity
HUX90_19660	COG0437	4 iron, 4 sulfur cluster binding
HUX90_19665	COG2414	aldehyde ferredoxin oxidoreductase
HUX90_19675	COG0437	4 iron, 4 sulfur cluster binding
HUX90_19680	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HUX90_19690	COG4529	Protein conserved in bacteria
HUX90_19710	COG3468	outer membrane autotransporter barrel domain protein
HUX90_19720	COG0307	riboflavin synthase, alpha
HUX90_19725	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUX90_19730	COG2814	Major facilitator Superfamily
HUX90_19735	COG0583	DNA-binding transcription factor activity
HUX90_19750	COG2814	Major facilitator Superfamily
HUX90_19755	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HUX90_19760	COG0791	NLP P60 protein
HUX90_19765	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HUX90_19770	COG1201	RNA secondary structure unwinding
HUX90_19780	COG0346	lactoylglutathione lyase activity
HUX90_19785	COG1902	pentaerythritol trinitrate reductase activity
HUX90_19790	COG1309	transcriptional regulator
HUX90_19795	COG3313	Fe-S protein
HUX90_19800	COG4989	oxidoreductase activity
HUX90_19805	COG2032	superoxide dismutase activity
HUX90_19810	COG1289	transmembrane transporter activity
HUX90_19815	COG1566	PFAM secretion protein HlyD family protein
HUX90_19830	COG3133	Outer membrane lipoprotein
HUX90_19840	COG3895	Periplasmic Protein
HUX90_19855	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HUX90_19860	COG0625	glutathione transferase activity
HUX90_19865	COG3104	oligopeptide transport
HUX90_19870	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HUX90_19880	COG4659	FMN binding
HUX90_19920	COG0673	inositol 2-dehydrogenase activity
HUX90_19930	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HUX90_19935	COG1263	PTS System
HUX90_19935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUX90_19940	COG1609	Transcriptional regulator
HUX90_19945	COG1028	Short-chain dehydrogenase reductase Sdr
HUX90_19950	COG1309	transcriptional regulator
HUX90_19955	COG3250	beta-galactosidase activity
HUX90_19970	COG5339	Protein conserved in bacteria
HUX90_19975	COG1482	cell wall glycoprotein biosynthetic process
HUX90_19980	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HUX90_19980	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HUX90_19985	COG0114	fumarate hydratase activity
HUX90_19995	COG2205	protein histidine kinase activity
HUX90_20000	COG0745	RESPONSE REGULATOR receiver
HUX90_20005	COG3136	membrane protein required for alginate biosynthesis
HUX90_20015	COG0531	amino acid
HUX90_20025	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HUX90_20030	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HUX90_20050	COG3591	Belongs to the peptidase S1B family
HUX90_20065	COG2814	Major facilitator Superfamily
HUX90_20070	COG0583	DNA-binding transcription factor activity
HUX90_20075	COG1940	carbohydrate kinase activity
HUX90_20080	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HUX90_20090	COG3381	protein complex oligomerization
HUX90_20095	COG3302	dmso reductase anchor subunit
HUX90_20100	COG0437	4 iron, 4 sulfur cluster binding
HUX90_20105	COG0243	molybdopterin cofactor binding
HUX90_20110	COG0243	molybdopterin cofactor binding
HUX90_20125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUX90_20140	COG4948	Mandelate Racemase Muconate Lactonizing
HUX90_20145	COG1063	alcohol dehydrogenase
HUX90_20155	COG0582	viral genome integration into host DNA
HUX90_20165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUX90_20190	COG1396	sequence-specific DNA binding
HUX90_20205	COG1846	Transcriptional regulator
HUX90_20230	COG2801	Transposase and inactivated derivatives
HUX90_20245	COG3077	Addiction module antitoxin, RelB DinJ family
HUX90_20250	COG2026	Addiction module toxin, RelE StbE family
HUX90_20270	COG1403	HNH endonuclease
HUX90_20275	COG0484	heat shock protein binding
HUX90_20285	COG1278	Cold shock
HUX90_20290	COG1278	Cold shock
HUX90_20305	COG3772	lysozyme
HUX90_20315	COG1278	Cold shock
HUX90_20340	COG5562	phage envelope protein
HUX90_20350	COG4220	transposase activity
HUX90_20370	COG1030	water channel activity
HUX90_20420	COG1196	nuclear chromosome segregation
HUX90_20455	COG5301	cellulose 1,4-beta-cellobiosidase activity
HUX90_20460	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HUX90_20465	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HUX90_20485	COG0246	Mannitol dehydrogenase
HUX90_20495	COG1802	Transcriptional regulator
HUX90_20500	COG4221	oxidoreductase activity
HUX90_20505	COG0339	signal peptide processing
HUX90_20510	COG1546	Belongs to the CinA family
HUX90_20515	COG3111	PFAM Bacterial OB fold (BOF) protein
HUX90_20520	COG3706	GGDEF domain
HUX90_20530	COG2814	Major facilitator Superfamily
HUX90_20535	COG0697	spore germination
HUX90_20540	COG2188	Transcriptional regulator
HUX90_20550	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUX90_20555	COG1447	Phosphotransferase system cellobiose-specific component IIA
HUX90_20565	COG2723	6-phospho-beta-galactosidase activity
HUX90_20575	COG4977	sequence-specific DNA binding
HUX90_20580	COG1846	Transcriptional regulator
HUX90_20600	COG0583	DNA-binding transcription factor activity
HUX90_20605	COG1012	belongs to the aldehyde dehydrogenase family
HUX90_20610	COG2066	Belongs to the glutaminase family
HUX90_20620	COG2199	diguanylate cyclase activity
HUX90_20630	COG3781	membrane
HUX90_20680	COG3210	domain, Protein
HUX90_20680	COG2911	Protein conserved in bacteria
HUX90_20685	COG1396	sequence-specific DNA binding
HUX90_20690	COG3550	peptidyl-serine autophosphorylation
HUX90_20700	COG3539	Fimbrial protein
HUX90_20710	COG3188	usher protein
HUX90_20715	COG3539	Fimbrial protein
HUX90_20720	COG3539	Fimbrial protein
HUX90_20725	COG3539	Fimbrial protein
HUX90_20730	COG0243	molybdopterin cofactor binding
HUX90_20745	COG3119	arylsulfatase activity
HUX90_20750	COG0641	radical SAM
HUX90_20760	COG4178	(ABC) transporter
HUX90_20765	COG4771	TonB-dependent receptor
HUX90_20770	COG0612	Peptidase, M16
HUX90_20775	COG0076	glutamate decarboxylase activity
HUX90_20780	COG0531	amino acid
HUX90_20795	COG2202	Pas domain
HUX90_20795	COG2199	diguanylate cyclase activity
HUX90_20795	COG2200	EAL domain
HUX90_20800	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HUX90_20805	COG0747	negative chemotaxis
HUX90_20810	COG0601	transmembrane transport
HUX90_20815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUX90_20820	COG0444	Belongs to the ABC transporter superfamily
HUX90_20825	COG4608	Belongs to the ABC transporter superfamily
HUX90_20830	COG1764	response to oxidative stress
HUX90_20850	COG1064	alcohol dehydrogenase
HUX90_20855	COG3093	addiction module antidote protein HigA
HUX90_20860	COG2864	formate dehydrogenase
HUX90_20865	COG0437	4 iron, 4 sulfur cluster binding
HUX90_20875	COG0697	spore germination
HUX90_20880	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HUX90_20885	COG4886	Leucine-rich repeat (LRR) protein
HUX90_20890	COG2223	nitrite transmembrane transporter activity
HUX90_20895	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HUX90_20900	COG1140	nitrate reductase beta subunit
HUX90_20905	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HUX90_20910	COG2181	nitrate reductase activity
HUX90_20915	COG0384	phenazine biosynthesis protein PhzF
HUX90_20920	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HUX90_20925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUX90_20955	COG3209	COG3209 Rhs family protein
HUX90_20970	COG0625	glutathione transferase activity
HUX90_20975	COG1113	amino acid transport
HUX90_20980	COG3391	amine dehydrogenase activity
HUX90_20985	COG4772	TonB-dependent receptor
HUX90_20990	COG1802	Transcriptional regulator
HUX90_20995	COG2130	NADP-dependent
HUX90_21000	COG1247	-acetyltransferase
HUX90_21005	COG3238	Protein conserved in bacteria
HUX90_21030	COG1177	transmembrane transport
HUX90_21035	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUX90_21040	COG3842	ATPase activity
HUX90_21045	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HUX90_21050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUX90_21055	COG1598	PFAM Uncharacterised protein family UPF0150
HUX90_21060	COG1724	mRNA binding
HUX90_21070	COG0826	peptidase U32
HUX90_21075	COG1396	sequence-specific DNA binding
HUX90_21080	COG3135	benzoate transporter
HUX90_21085	COG0675	Transposase, IS605 OrfB family
HUX90_21100	COG0500	methyltransferase
HUX90_21105	COG1275	C4-dicarboxylate transporter malic acid transport protein
HUX90_21110	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HUX90_21115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUX90_21120	COG2841	Protein conserved in bacteria
HUX90_21130	COG5383	Protein conserved in bacteria
HUX90_21135	COG0583	DNA-binding transcription factor activity
HUX90_21140	COG0840	transmembrane signaling receptor activity
HUX90_21155	COG3038	cytochrome b561
HUX90_21160	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HUX90_21165	COG1012	belongs to the aldehyde dehydrogenase family
HUX90_21170	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HUX90_21175	COG1643	Atp-dependent helicase
HUX90_21185	COG0671	phosphoesterase, PA-phosphatase related
HUX90_21185	COG2453	phosphatase
HUX90_21195	COG4589	Belongs to the CDS family
HUX90_21200	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HUX90_21210	COG0667	Aldo Keto reductase
HUX90_21215	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HUX90_21220	COG3327	negative regulation of DNA-templated transcription, initiation
HUX90_21225	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HUX90_21230	COG0183	Belongs to the thiolase family
HUX90_21235	COG2050	protein possibly involved in aromatic compounds catabolism
HUX90_21240	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUX90_21245	COG1024	Enoyl-CoA hydratase
HUX90_21250	COG1024	Enoyl-CoA hydratase
HUX90_21255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUX90_21260	COG2151	metal-sulfur cluster biosynthetic enzyme
HUX90_21265	COG3396	Phenylacetate-CoA oxygenase
HUX90_21270	COG3460	Phenylacetate-CoA oxygenase
HUX90_21275	COG3396	Phenylacetate-CoA oxygenase
HUX90_21280	COG1012	belongs to the aldehyde dehydrogenase family
HUX90_21280	COG2030	dehydratase
HUX90_21285	COG3733	amine oxidase
HUX90_21290	COG1012	belongs to the aldehyde dehydrogenase family
HUX90_21295	COG2207	Transcriptional regulator
HUX90_21300	COG3784	Protein of unknown function (DUF1318)
HUX90_21310	COG2911	Protein conserved in bacteria
HUX90_21315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUX90_21320	COG3187	Heat shock protein
HUX90_21325	COG3042	response to heat
HUX90_21330	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HUX90_21330	COG0674	pyruvate-flavodoxin oxidoreductase activity
HUX90_21330	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUX90_21330	COG1013	pyruvate-flavodoxin oxidoreductase activity
HUX90_21335	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HUX90_21340	COG0589	response to stress
HUX90_21355	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HUX90_21360	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HUX90_21365	COG5301	cellulose 1,4-beta-cellobiosidase activity
HUX90_21400	COG1196	nuclear chromosome segregation
HUX90_21480	COG1475	DNA binding
HUX90_21485	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HUX90_21495	COG3772	lysozyme
HUX90_21510	COG3064	Membrane
HUX90_21540	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HUX90_21555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUX90_21610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUX90_21615	COG3723	Recombinational DNA repair protein, rece pathway
HUX90_21635	COG0582	viral genome integration into host DNA
HUX90_21645	COG0513	Belongs to the DEAD box helicase family
HUX90_21655	COG3706	GGDEF domain
HUX90_21660	COG2840	Smr protein MutS2
HUX90_21665	COG0583	DNA-binding transcription factor activity
HUX90_21670	COG1473	amidohydrolase
HUX90_21675	COG1473	amidohydrolase
HUX90_21680	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HUX90_21685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUX90_21690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUX90_21695	COG0589	response to stress
HUX90_21700	COG3182	Iron-regulated membrane protein
HUX90_21705	COG0668	transmembrane transport
HUX90_21710	COG4166	transmembrane transport
HUX90_21715	COG0583	DNA-binding transcription factor activity
HUX90_21720	COG1073	alpha beta
HUX90_21735	COG2866	Carboxypeptidase
HUX90_21740	COG4948	Mandelate Racemase Muconate Lactonizing
HUX90_21745	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HUX90_21750	COG3283	Transcriptional regulator of aromatic amino acids metabolism
HUX90_21760	COG3106	COG3106 Predicted ATPase
HUX90_21765	COG1609	Transcriptional regulator
HUX90_21775	COG3842	ATPase activity
HUX90_21780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUX90_21785	COG1554	hydrolase, family 65, central catalytic
HUX90_21790	COG0673	inositol 2-dehydrogenase activity
HUX90_21795	COG1082	Xylose isomerase domain protein TIM barrel
HUX90_21800	COG1063	alcohol dehydrogenase
HUX90_21805	COG0395	ABC-type sugar transport system, permease component
HUX90_21810	COG1175	transmembrane transport
HUX90_21815	COG1653	transport
HUX90_21820	COG0366	Alpha amylase catalytic
HUX90_21825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUX90_21835	COG1983	PspC domain protein
HUX90_21845	COG1842	Phage shock protein A
HUX90_21850	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HUX90_21855	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HUX90_21860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUX90_21865	COG1012	belongs to the aldehyde dehydrogenase family
HUX90_21870	COG1396	sequence-specific DNA binding
HUX90_21870	COG1917	Cupin 2, conserved barrel domain protein
HUX90_21880	COG0174	glutamine synthetase
HUX90_21890	COG0531	amino acid
HUX90_21900	COG4166	transmembrane transport
HUX90_21905	COG4168	peptide transport system, permease
HUX90_21910	COG4171	peptide transport system, permease
HUX90_21915	COG4172	Belongs to the ABC transporter superfamily
HUX90_21920	COG4172	Belongs to the ABC transporter superfamily
HUX90_21925	COG2852	Protein conserved in bacteria
HUX90_21930	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HUX90_21935	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUX90_21935	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUX90_21950	COG5001	Diguanylate cyclase
HUX90_21960	COG1349	DNA-binding transcription factor activity
HUX90_21970	COG0023	Translation Initiation Factor
HUX90_21980	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HUX90_21985	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HUX90_21990	COG0671	phosphoesterase, PA-phosphatase related
HUX90_22000	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HUX90_22020	COG0583	DNA-binding transcription factor activity
HUX90_22025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HUX90_22035	COG0616	signal peptide processing
HUX90_22040	COG1028	Short-chain dehydrogenase reductase Sdr
HUX90_22045	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HUX90_22050	COG1187	pseudouridine synthase activity
HUX90_22055	COG0009	L-threonylcarbamoyladenylate synthase
HUX90_22060	COG0613	PHP domain protein
HUX90_22070	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUX90_22075	COG0512	Glutamine amidotransferase of anthranilate synthase
HUX90_22075	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HUX90_22080	COG0135	phosphoribosylanthranilate isomerase activity
HUX90_22080	COG0134	indole-3-glycerol-phosphate synthase activity
HUX90_22095	COG3729	General stress protein
HUX90_22100	COG3685	Protein conserved in bacteria
HUX90_22105	COG3685	Protein conserved in bacteria
HUX90_22110	COG3047	cAMP biosynthetic process
HUX90_22130	COG1607	acyl-coa hydrolase
HUX90_22135	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HUX90_22140	COG2350	Protein conserved in bacteria
HUX90_22145	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HUX90_22165	COG4608	Belongs to the ABC transporter superfamily
HUX90_22170	COG0444	Belongs to the ABC transporter superfamily
HUX90_22175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUX90_22180	COG0601	transmembrane transport
HUX90_22185	COG4166	transmembrane transport
HUX90_22195	COG2095	MarC family integral membrane protein
HUX90_22200	COG1454	alcohol dehydrogenase
HUX90_22200	COG1012	belongs to the aldehyde dehydrogenase family
HUX90_22205	COG1435	thymidine kinase activity
HUX90_22215	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HUX90_22220	COG0745	RESPONSE REGULATOR receiver
HUX90_22225	COG1752	Esterase of the alpha-beta hydrolase superfamily
HUX90_22235	COG0788	formyltetrahydrofolate deformylase activity
HUX90_22255	COG2181	nitrate reductase activity
HUX90_22260	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HUX90_22265	COG1140	nitrate reductase beta subunit
HUX90_22270	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HUX90_22275	COG2223	nitrite transmembrane transporter activity
HUX90_22280	COG3850	Histidine kinase
HUX90_22285	COG2197	response regulator
HUX90_22290	COG4932	domain protein
HUX90_22295	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HUX90_22300	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HUX90_22305	COG4572	Cation transport regulator
HUX90_22310	COG0387	Pfam Sodium calcium exchanger
HUX90_22335	COG2912	Transglutaminase-like superfamily
HUX90_22340	COG3094	Invasion gene expression up-regulator, SirB
HUX90_22345	COG2890	protein-(glutamine-N5) methyltransferase activity
HUX90_22370	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUX90_22375	COG0659	secondary active sulfate transmembrane transporter activity
HUX90_22390	COG0012	GTP binding
HUX90_22395	COG3468	outer membrane autotransporter barrel domain protein
HUX90_22400	COG3284	Transcriptional regulator
HUX90_22405	COG2376	Dihydroxyacetone kinase
HUX90_22410	COG1461	Dihydroxyacetone kinase
HUX90_22415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUX90_22415	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
HUX90_22415	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUX90_22435	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HUX90_22445	COG1619	proteins homologs of microcin C7 resistance protein MccF
HUX90_22455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUX90_22465	COG2719	SpoVR family
HUX90_22480	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HUX90_22485	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUX90_22490	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUX90_22505	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUX90_22530	COG2894	cell division
HUX90_22585	COG2200	EAL domain
HUX90_22610	COG2200	EAL domain
HUX90_22615	COG0789	Transcriptional regulator
HUX90_22620	COG5562	phage envelope protein
HUX90_22635	COG0538	isocitrate dehydrogenase activity
HUX90_22640	COG1403	HNH endonuclease
HUX90_22645	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HUX90_22660	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HUX90_22670	COG3778	Protein conserved in bacteria
HUX90_22675	COG3299	homolog of phage Mu protein gp47
HUX90_22695	COG4228	DNA circulation
HUX90_22715	COG4386	tail sheath protein
HUX90_22760	COG4695	Portal protein
HUX90_22770	COG1802	Transcriptional regulator
HUX90_22770	COG4626	Terminase