locus-tag	class	description
K663_00005	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
K663_00010	ENOG4108UHJ	MAF-like protein
K663_00015	ENOG4105E2X	shikimate dehydrogenase
K663_00020	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
K663_00030	ENOG4107TNS	sigma 54 modulation protein ribosomal protein S30ea
K663_00035	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
K663_00070	ENOG4108ZZ3	UPF0260 protein
K663_00080	ENOG4105C72	UPF0176 protein
K663_00090	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
K663_00095	ENOG4105DFA	alanine racemase domain protein
K663_00110	ENOG4105TXM	Domain of unknown function (DUF3576)
K663_00115	ENOG4105C8T	Leucyl-tRNA synthetase
K663_00130	ENOG4105E0X	reductase
K663_00135	ENOG4108JQC	penicillin-binding protein 1A
K663_00145	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
K663_00150	ENOG4108ZCF	integral membrane protein
K663_00155	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
K663_00170	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
K663_00175	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
K663_00180	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
K663_00185	ENOG4107QJE	Chromosome Partitioning Protein
K663_00190	ENOG4105FA0	parb-like partition protein
K663_00195	ENOG4105CD8	aminopeptidase N
K663_00210	ENOG4105DHJ	ABC, transporter
K663_00225	ENOG4105C5I	Dehydrogenase
K663_00235	ENOG4107QRT	dEAD DEAH box helicase
K663_00260	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
K663_00270	ENOG4105CIH	Imidazole acetol-phosphate transaminase
K663_00275	ENOG4105F0N	pyrophosphate phospho-hydrolase
K663_00285	ENOG4105CUT	histidyl-tRNA synthetase
K663_00290	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
K663_00295	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
K663_00310	ENOG4105NAU	thioesterase Superfamily protein
K663_00320	ENOG4108IJ8	ABC transporter
K663_00335	ENOG4107QPD	alcohol dehydrogenase
K663_00345	ENOG4105C4W	S-formylglutathione hydrolase
K663_00350	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
K663_00355	ENOG4105CUB	amino acid
K663_00360	ENOG4105C2C	drug resistance transporter, Bcr CflA
K663_00395	ENOG4108UXN	response regulator
K663_00405	ENOG4105W0E	50S ribosomal protein L33
K663_00425	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
K663_00455	ENOG4105EUB	pirin domain protein
K663_00465	ENOG4105CAK	Cell division ATP-binding protein ftsE
K663_00490	ENOG4105CIH	Imidazole acetol-phosphate transaminase
K663_00500	ENOG4105DWV	Homoserine O-trans-acetylase
K663_00510	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
K663_00520	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
K663_00525	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
K663_00530	ENOG410829K	Lysine exporter protein (Lyse ygga)
K663_00535	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
K663_00540	ENOG41082BR	50S ribosomal protein L35
K663_00570	ENOG4105C4K	Nad synthetase
K663_00575	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
K663_00595	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
K663_00600	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
K663_00605	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
K663_00630	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
K663_00635	ENOG4108IUX	(ABC) transporter
K663_00645	ENOG4105E0X	reductase
K663_00670	ENOG4105DC1	bifunctional purine biosynthesis protein purh
K663_00680	ENOG4105DJV	ribulose-phosphate 3-epimerase
K663_00690	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
K663_00695	ENOG4105D0M	Protease HtpX homolog
K663_00715	ENOG4108UUM	single-stranded DNA-binding protein
K663_00720	ENOG4105CE1	Ferrous iron transport protein b
K663_00745	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
K663_00755	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
K663_00760	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
K663_00765	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
K663_00770	ENOG4106BRA	Membrane
K663_00785	ENOG4105Y3U	Transglycosylase-associated protein
K663_00790	ENOG4105Y3U	Transglycosylase-associated protein
K663_00805	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
K663_00825	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
K663_00830	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
K663_00845	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
K663_00850	ENOG4105C9K	Endothelin-converting enzyme 1
K663_00860	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
K663_00865	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
K663_00870	ENOG4108Z03	MAF-like protein
K663_00935	ENOG4105EMU	Dehydrogenase
K663_00950	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
K663_00975	ENOG4105DEI	Mannitol dehydrogenase
K663_00980	ENOG4105D2H	Uronic isomerase
K663_00985	ENOG4105DPW	Major facilitator superfamily MFS_1
K663_00990	ENOG4105CXK	mandelate racemase muconate lactonizing
K663_00995	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
K663_01000	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
K663_01005	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
K663_01010	ENOG4105ETE	Transcriptional regulator (LacI family
K663_01050	ENOG4105C01	Dihydroxy-acid dehydratase
K663_01100	ENOG4105K63	Thioredoxin
K663_01105	ENOG4105D3R	alkyl hydroperoxide reductase
K663_01110	ENOG41080HT	Transcriptional regulator, arsr family
K663_01115	ENOG4108JJ8	(ABC) transporter
K663_01120	ENOG4108JJ9	ABC, transporter
K663_01125	ENOG4105C4M	(Ubiquinol oxidase) subunit I
K663_01130	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
K663_01140	ENOG4107QX9	Thiol disulfide interChange protein
K663_01160	ENOG41080HT	Transcriptional regulator, arsr family
K663_01165	ENOG4105BZS	acriflavin resistance protein
K663_01180	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
K663_01195	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
K663_01200	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
K663_01205	ENOG4105C7W	Xanthine dehydrogenase
K663_01225	ENOG4105DC7	peptidase M24
K663_01250	ENOG4108JJ7	ABC transporter
K663_01255	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
K663_01275	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
K663_01285	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
K663_01290	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
K663_01295	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
K663_01320	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
K663_01325	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
K663_01330	ENOG4107U9T	Pfam:Ribonuclease_BN
K663_01335	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
K663_01350	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
K663_01355	ENOG4105JAB	phenazine biosynthesis protein, phzf family
K663_01370	ENOG4105C9U	ATP-dependent DNA helicase RecQ
K663_01380	ENOG4105CBX	hi0933 family
K663_01385	ENOG4105PGM	cation diffusion facilitator family transporter
K663_01405	ENOG4108URH	decarboxylase
K663_01415	ENOG4105BZU	Histidine kinase
K663_01420	ENOG4108YZA	Nitrogen regulatory protein pii
K663_01430	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
K663_01460	ENOG4105ED4	portal protein
K663_01660	ENOG4105Y2X	UPF0335 protein
K663_01685	ENOG4108KU3	Integrase
K663_01695	ENOG4105F0I	Aminotransferase
K663_01700	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
K663_01715	ENOG4105MP9	class II Aldolase
K663_01725	ENOG4108V1T	peptidylprolyl cis-trans isomerase
K663_01730	ENOG4105C02	permease
K663_01735	ENOG4105C3F	Signal peptidase i
K663_01740	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
K663_01750	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
K663_01760	ENOG4105BZ9	Cytochrome C oxidase, subunit I
K663_01765	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
K663_01775	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
K663_01780	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
K663_01790	ENOG4105D98	threonine synthase
K663_01805	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
K663_01815	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
K663_01820	ENOG4105IJY	hydroxylase
K663_01825	ENOG4105C28	cystathionine
K663_01830	ENOG4105KHC	sulfurtransferase
K663_01840	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
K663_01860	ENOG4105EPD	Oligopeptide transporter, Opt family
K663_01870	ENOG4105GSS	Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress (By similarity)
K663_01875	ENOG4105DFP	Integrase
K663_01965	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
K663_01975	ENOG4105C0D	helicase
K663_01980	ENOG4105EYH	Exonuclease
K663_01995	ENOG4105EYH	Exonuclease
K663_02000	ENOG4107RH8	nuclease SbcCD subunit D
K663_02085	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
K663_02110	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
K663_02290	ENOG4107QRT	dEAD DEAH box helicase
K663_02320	ENOG4105C0D	helicase
K663_02340	ENOG4107ZSV	Receptor
K663_02350	ENOG4105ES1	acyl-CoA reductase
K663_02360	ENOG4105CHR	reductase
K663_02375	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
K663_02385	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
K663_02390	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
K663_02400	ENOG4107EFR	Flavocytochrome c
K663_02405	ENOG4105CC0	LysR family Transcriptional regulator
K663_02450	ENOG4105CYM	Glutathione S-transferase
K663_02460	ENOG4107ZSV	Receptor
K663_02500	ENOG4107ZSV	Receptor
K663_02525	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
K663_02545	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
K663_02550	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K663_02560	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
K663_02595	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
K663_02600	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
K663_02625	ENOG4107GFK	fumarate
K663_02635	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
K663_02645	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
K663_02670	ENOG4105KUZ	arsenate reductase
K663_02675	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
K663_02680	ENOG4105C5X	domain protein
K663_02690	ENOG41082R8	50S ribosomal protein l32
K663_02695	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
K663_02700	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
K663_02705	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
K663_02710	ENOG4105WJX	transcriptional regulator MERR family
K663_02725	ENOG4105DVT	helicase
K663_02730	ENOG4105DK7	lysyl-tRNA synthetase
K663_02755	ENOG4105BZU	Histidine kinase
K663_02760	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
K663_02775	ENOG4105CHM	Aminotransferase
K663_02780	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
K663_02790	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
K663_02795	ENOG4105BZU	Histidine kinase
K663_02805	ENOG4105CBT	Fructose-1,6-bisphosphatase
K663_02815	ENOG4105D6E	homoserine dehydrogenase
K663_02835	ENOG4105M8F	Biopolymer transport protein exbD tolR
K663_02850	ENOG4105BZ1	(ABC) transporter
K663_02860	ENOG4107S8C	mandelate racemase muconate lactonizing
K663_02895	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
K663_02915	ENOG4105M7P	phage repressor
K663_02925	ENOG4105VCD	cytoplasmic protein
K663_02930	ENOG4105D22	carbon starvation protein
K663_02940	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
K663_02950	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
K663_02955	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
K663_02960	ENOG4105VG0	50S ribosomal protein l34
K663_02975	ENOG4105C03	ribonuclease
K663_02980	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
K663_02985	ENOG4108JQC	penicillin-binding protein 1A
K663_02990	ENOG4107EFR	Flavocytochrome c
K663_02995	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
K663_03035	ENOG41067HS	methyltransferase
K663_03040	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
K663_03055	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
K663_03070	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
K663_03075	ENOG410903D	sensor protein
K663_03105	ENOG4105C2N	RNA methyltransferase TrmH family group 3
K663_03110	ENOG4105KPY	Small multidrug resistance protein
K663_03115	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
K663_03120	ENOG4105C5H	ABC transporter
K663_03135	ENOG4105BZU	Histidine kinase
K663_03140	ENOG4105FG0	Nitroreductase
K663_03150	ENOG4105F1J	Homogentisate 1,2-dioxygenase
K663_03175	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
K663_03190	ENOG4105CSH	Transporter
K663_03205	ENOG4105D6J	arsenicaL-resistance protein
K663_03265	ENOG4105C7W	Xanthine dehydrogenase
K663_03270	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
K663_03275	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
K663_03300	ENOG4105E2Y	ABC, transporter
K663_03305	ENOG4105MRR	Transcriptional regulator (By similarity)
K663_03345	ENOG4107RDJ	Sulfotransferase
K663_03390	ENOG4105CHU	acetyl-coa acetyltransferase
K663_03395	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
K663_03410	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
K663_03420	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
K663_03445	ENOG4105CQB	FAD linked oxidase domain protein
K663_03470	ENOG4105CHR	reductase
K663_03485	ENOG4105HSS	phospholipase C
K663_03495	ENOG4105D5T	phosphonate abc transporter
K663_03510	ENOG4106KNT	transcriptional regulator
K663_03520	ENOG4105EQR	Transposase IS116 IS110 IS902
K663_03555	ENOG4105D82	Glutamate dehydrogenase
K663_03580	ENOG4105E5H	Transposase
K663_03620	ENOG4105E0K	tonB-dependent siderophore receptor
K663_03625	ENOG4105NIV	Esterase
K663_03645	ENOG4105DFP	Integrase
K663_03650	ENOG4105DCF	alanine dehydrogenase
K663_03655	ENOG4105HF0	Membrane
K663_03660	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
K663_03665	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
K663_03680	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
K663_03715	ENOG4105C2X	Arabinose 5-phosphate isomerase
K663_03720	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
K663_03780	ENOG4107Y80	Major Facilitator superfamily
K663_03790	ENOG4105D7A	ATP-binding protein
K663_03800	ENOG4105EPW	hflc protein
K663_03805	ENOG4107QJR	hflk protein
K663_03815	ENOG4105K4P	CoA-binding domain protein
K663_03830	ENOG4105CHR	reductase
K663_03840	ENOG4108ESX	Receptor
K663_03850	ENOG4107E2E	PKHD-type hydroxylase
K663_03855	ENOG41081YB	ApbE family
K663_03875	ENOG4105C7I	Dehydrogenase
K663_03890	ENOG4108KPJ	rna polymerase sigma factor
K663_03905	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
K663_03920	ENOG4105D05	Receptor
K663_03935	ENOG4105F4R	Transcriptional regulator mode
K663_03940	ENOG4105BZU	Histidine kinase
K663_03945	ENOG4105HEI	LysR family (Transcriptional regulator
K663_03950	ENOG4105F27	Major Facilitator
K663_03975	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
K663_03980	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
K663_03985	ENOG4107QXV	Phosphate transporter
K663_03990	ENOG4107GRR	phosphate transport regulator
K663_04015	ENOG4105CDH	Citrulline--aspartate ligase
K663_04025	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
K663_04030	ENOG41062D9	Histidine kinase
K663_04035	ENOG4105CSH	Transporter
K663_04040	ENOG4108RWN	rrna methyltransferase
K663_04050	ENOG4108EQA	pts system
K663_04055	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
K663_04060	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
K663_04065	ENOG4105EB3	Histidine kinase
K663_04070	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
K663_04075	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
K663_04085	ENOG4105DP0	ferredoxin-NADP reductase
K663_04100	ENOG4107QX8	SPFH domain, Band 7 family protein
K663_04105	ENOG4105CI0	Citrate lyase
K663_04115	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
K663_04125	ENOG4105CFH	Aspartokinase
K663_04140	ENOG4107YPT	transcriptional regulator
K663_04150	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
K663_04170	ENOG4105CIH	Imidazole acetol-phosphate transaminase
K663_04175	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
K663_04220	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
K663_04240	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
K663_04250	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
K663_04260	ENOG4107TSN	permease
K663_04270	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
K663_04275	ENOG4105Y49	secretion protein, HlyD family
K663_04295	ENOG4105C7W	Xanthine dehydrogenase
K663_04300	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
K663_04305	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
K663_04335	ENOG4107RH7	Nicotinate phosphoribosyltransferase
K663_04355	ENOG4105E3J	oxidoreductase
K663_04375	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
K663_04390	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
K663_04395	ENOG4107QJQ	Mate efflux family protein
K663_04410	ENOG4105DEN	Luciferase family
K663_04425	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
K663_04440	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
K663_04445	ENOG4107ZSV	Receptor
K663_04465	ENOG4108Z9K	Osmotically inducible protein
K663_04470	ENOG4105DFI	Membrane
K663_04485	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
K663_04490	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
K663_04495	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
K663_04500	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
K663_04505	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
K663_04515	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
K663_04525	ENOG4105C25	Primosomal protein n'
K663_04535	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
K663_04550	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
K663_04555	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
K663_04560	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
K663_04565	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
K663_04570	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
K663_04580	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
K663_04590	ENOG4105C8U	phosphate abc transporter
K663_04600	ENOG4105BZU	Histidine kinase
K663_04615	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
K663_04625	ENOG4105CH2	amidohydrolase
K663_04645	ENOG4105CGZ	zinc metallopeptidase
K663_04660	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
K663_04670	ENOG4105ED9	Protein of unknown function (DUF455)
K663_04675	ENOG4105DR5	peptidase
K663_04680	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
K663_04735	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
K663_04745	ENOG4105VW4	glutaredoxin 3
K663_04780	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
K663_04805	ENOG4105DZG	Dehydrogenase
K663_04810	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
K663_04840	ENOG41076PI	Short-chain dehydrogenase reductase Sdr
K663_04860	ENOG4105CK5	oxidoreductase
K663_04865	ENOG4107QPD	alcohol dehydrogenase
K663_04870	ENOG4105CZA	synthase
K663_04880	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
K663_04885	ENOG4108TGR	phosphatase
K663_04900	ENOG4108IAJ	Nad-dependent epimerase dehydratase
K663_04925	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
K663_04940	ENOG4105EMU	Dehydrogenase
K663_04970	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
K663_05005	ENOG4105CD5	CoA-binding domain protein
K663_05020	ENOG4105BZU	Histidine kinase
K663_05025	ENOG4108ZXC	Two component transcriptional regulator, luxr family
K663_05030	ENOG4108ZXC	Two component transcriptional regulator, luxr family
K663_05065	ENOG4105W87	Cbs domain
K663_05070	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
K663_05075	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
K663_05080	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
K663_05085	ENOG4105CY0	Metallo-Beta-Lactamase
K663_05095	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
K663_05120	ENOG4105VN1	Heat shock protein
K663_05145	ENOG4105E2K	Glycosyl transferase (Group 1
K663_05155	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
K663_05160	ENOG4107B2H	carbonic anhydrase
K663_05165	ENOG4105CHH	sulfate transporter
K663_05175	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
K663_05180	ENOG4105E0F	Histidine kinase
K663_05185	ENOG4105D7W	serine acetyltransferase
K663_05200	ENOG4105DX0	Hemolysin A
K663_05205	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
K663_05210	ENOG4105BZS	acriflavin resistance protein
K663_05215	ENOG4105KAV	tspo and mbr like protein
K663_05230	ENOG4105II7	pyrroline-5-carboxylate reductase
K663_05235	ENOG4105HDK	L-asparaginase
K663_05245	ENOG4108VJ1	Transcriptional regulator (CarD family
K663_05250	ENOG4108Z4U	Ferredoxin
K663_05255	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
K663_05265	ENOG4105DR5	peptidase
K663_05285	ENOG4108S55	polysaccharide biosynthesis protein
K663_05290	ENOG4107Z36	nucleotidyl transferase
K663_05325	ENOG4105D6Z	AFG1 family ATPase
K663_05330	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
K663_05340	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
K663_05345	ENOG4105C7S	Dehydrogenase
K663_05350	ENOG4107QN2	dihydrolipoyl dehydrogenase
K663_05355	ENOG4105BZU	Histidine kinase
K663_05360	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
K663_05370	ENOG4105DIN	metallophosphoesterase
K663_05380	ENOG4105CRK	lysyL-tRNA synthetase
K663_05385	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
K663_05395	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
K663_05400	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
K663_05410	ENOG4105CE9	30S ribosomal protein S2
K663_05415	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
K663_05420	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
K663_05425	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
K663_05435	ENOG4105KNE	Phosphatidate cytidylyltransferase
K663_05445	ENOG4105DZP	Membrane-associated zinc metalloprotease
K663_05460	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
K663_05465	ENOG41082FS	50S ribosomal protein L31
K663_05475	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
K663_05490	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
K663_05495	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
K663_05515	ENOG4105M6F	mutator MutT protein
K663_05520	ENOG4108UQY	Iron-storage protein
K663_05535	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
K663_05540	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
K663_05545	ENOG4105KAF	membrAne
K663_05560	ENOG4105CTB	Polyprenyl synthetase
K663_05565	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
K663_05570	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
K663_05575	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
K663_05580	ENOG4105C5Q	Transcriptional regulator
K663_05585	ENOG4105C1G	acyl-Coa dehydrogenase
K663_05595	ENOG4107QX3	carboxylase
K663_05620	ENOG4105CRQ	synthase (Component I)
K663_05630	ENOG4105CP7	Triose-phosphate isomerase
K663_05640	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
K663_05650	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
K663_05660	ENOG4108F90	4-oxalocrotonate tautomerase
K663_05670	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
K663_05675	ENOG4107ZGG	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
K663_05680	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
K663_05690	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
K663_05700	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K663_05710	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
K663_05715	ENOG4105CYM	Glutathione S-transferase
K663_05720	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
K663_05725	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
K663_05730	ENOG4105BZU	Histidine kinase
K663_05745	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
K663_05760	ENOG41074H6	response regulator
K663_05790	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
K663_05795	ENOG4105FDP	GntR family transcriptional regulator
K663_05805	ENOG4105DUX	Transporter
K663_05845	ENOG4105E3B	Multicopper oxidase
K663_05865	ENOG4105CH2	amidohydrolase
K663_05870	ENOG4108RYR	transcriptional regulator AsnC family
K663_05875	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
K663_05880	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
K663_05920	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
K663_05935	ENOG4105CJP	fad dependent oxidoreductase
K663_05945	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
K663_06000	ENOG4107QM5	aconitate hydratase
K663_06010	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
K663_06025	ENOG4105WD1	Membrane
K663_06030	ENOG4105IFJ	Histidine kinase
K663_06035	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
K663_06050	ENOG4105C5H	ABC transporter
K663_06060	ENOG4108V06	Glutathione peroxidase
K663_06065	ENOG4105EN6	Membrane
K663_06070	ENOG4105D07	Signal peptide peptidase, SppA
K663_06075	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
K663_06085	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
K663_06095	ENOG4105DTN	riboflavin biosynthesis protein ribF
K663_06105	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
K663_06115	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
K663_06125	ENOG4105M08	Membrane
K663_06130	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
K663_06140	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
K663_06170	ENOG4108ZAF	Molybdopterin
K663_06175	ENOG4105C5Q	Transcriptional regulator
K663_06180	ENOG410635A	Membrane
K663_06185	ENOG4105D7W	serine acetyltransferase
K663_06200	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
K663_06255	ENOG4105DU6	RNA polymerase
K663_06260	ENOG4107E2E	PKHD-type hydroxylase
K663_06290	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
K663_06295	ENOG4105BZS	acriflavin resistance protein
K663_06300	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
K663_06305	ENOG4105ETT	transcriptional Regulator, LysR family
K663_06330	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
K663_06335	ENOG4108UYB	regulatoR
K663_06350	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
K663_06355	ENOG4105CCU	oxidase (Subunit III)
K663_06360	ENOG4105BZ9	Cytochrome C oxidase, subunit I
K663_06365	ENOG4105E2S	oxidase) subunit II
K663_06370	ENOG4105CSH	Transporter
K663_06380	ENOG4105BZU	Histidine kinase
K663_06395	ENOG4105DFH	Transport of potassium into the cell (By similarity)
K663_06420	ENOG4105C3M	thioredoxin reductase
K663_06435	ENOG4105CEY	Amp-dependent synthetase and ligase
K663_06490	ENOG4105CAQ	asparagine synthetase
K663_06495	ENOG4105D3Q	Sugar transferase
K663_06515	ENOG4107Y2G	Glycosyl transferase (Group 1
K663_06535	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
K663_06540	ENOG4105C7B	Threonine dehydratase
K663_06545	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
K663_06560	ENOG4108YZN	class I peptide chain release factor
K663_06575	ENOG4105CS1	NAD(P)H quinone oxidoreductase
K663_06580	ENOG4105C2I	pirin domain protein
K663_06590	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
K663_06605	ENOG4105EMN	RNA polymerase sigma factor
K663_06615	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
K663_06620	ENOG4105DHP	deoxycytidine triphosphate deaminase
K663_06625	ENOG4105KG3	cytidine deaminase
K663_06635	ENOG4108ZTZ	UPF0262 protein
K663_06640	ENOG4105CDU	Replicative dna helicase
K663_06650	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
K663_06670	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
K663_06675	ENOG4105C26	Dehydrogenase
K663_06720	ENOG4107QJE	Chromosome Partitioning Protein
K663_06735	ENOG4105C5I	Dehydrogenase
K663_06745	ENOG4105DNH	Major Facilitator
K663_06750	ENOG4105MP9	class II Aldolase
K663_06755	ENOG4105DFP	Integrase
K663_06760	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
K663_06765	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
K663_06770	ENOG4105BZU	Histidine kinase
K663_06785	ENOG4108JA2	transcriptioN-repair coupling factor
K663_06795	ENOG4105CB5	ATP-dependent DNA helicase recG
K663_06805	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
K663_06810	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
K663_06825	ENOG4108NVR	Methyl-accepting chemotaxis
K663_06840	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
K663_06850	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
K663_06855	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
K663_06880	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
K663_06915	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
K663_06960	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
K663_06965	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
K663_06980	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
K663_06985	ENOG4108ZP8	Acetolactate synthase small subunit
K663_06995	ENOG4105C7K	acetolactate synthase
K663_07000	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
K663_07005	ENOG4105EAC	phosphoserine phosphatase
K663_07015	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
K663_07030	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
K663_07040	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
K663_07045	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
K663_07050	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
K663_07085	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
K663_07090	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
K663_07095	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
K663_07100	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
K663_07105	ENOG4108ESZ	Glycogen debranching enzyme
K663_07115	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K663_07120	ENOG4105E50	uracil-dna glycosylase
K663_07150	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
K663_07165	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
K663_07170	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
K663_07175	ENOG4108YZG	isomerase
K663_07190	ENOG4105DHZ	alpha beta
K663_07215	ENOG4107QMP	dna polymerase iii subunits gamma and tau
K663_07220	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
K663_07225	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
K663_07235	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
K663_07250	ENOG4105C6K	Malic enzyme
K663_07255	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
K663_07265	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
K663_07270	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
K663_07275	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
K663_07280	ENOG4105CAT	Cytidine monophosphate kinase
K663_07290	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
K663_07305	ENOG4105C4R	Atp-dependent dna helicase
K663_07320	ENOG4105KPV	Transcriptional regulator
K663_07330	ENOG4106H78	methyltransferase
K663_07360	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
K663_07365	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
K663_07370	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
K663_07375	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
K663_07380	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
K663_07420	ENOG4105F7P	transcriptional regulator AsnC family
K663_07425	ENOG4105BZU	Histidine kinase
K663_07435	ENOG4105I5W	Transporter
K663_07445	ENOG4105D7T	ABC transporter
K663_07455	ENOG4105C8Q	Methyl-accepting chemotaxis
K663_07470	ENOG4105IIU	Aminopeptidase
K663_07480	ENOG41084X4	Acylphosphatase (EC 3.6.1.7)
K663_07490	ENOG4108V9Q	carbonic anhydrase
K663_07495	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
K663_07500	ENOG4108Z1B	Cyclase dehydrase
K663_07510	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
K663_07535	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
K663_07540	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
K663_07545	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
K663_07550	ENOG4105DXN	mazG family
K663_07555	ENOG4105CSH	Transporter
K663_07570	ENOG4105F8V	Hydrolase, tatD family
K663_07580	ENOG4107QRG	dna polymerase iii
K663_07585	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
K663_07590	ENOG4105DZ1	carboxypeptidase
K663_07595	ENOG4105CVE	Lytic murein transglycosylase
K663_07610	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
K663_07620	ENOG4108MWI	inositol mono-phosphatase
K663_07625	ENOG4105K63	Thioredoxin
K663_07630	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
K663_07640	ENOG4108S0S	Nucleotidyl transferase
K663_07645	ENOG4105EHM	Aminoglycoside phosphotransferase
K663_07650	ENOG4108097	ATP-binding protein
K663_07655	ENOG4105I8F	Histidine kinase
K663_07660	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
K663_07665	ENOG4108UJU	UPF0301 protein
K663_07675	ENOG4105FYV	Amp nucleosidase
K663_07690	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
K663_07715	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
K663_07725	ENOG4108NVM	synthesis repressor PhaR
K663_07740	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
K663_07745	ENOG4105CSH	Transporter
K663_07755	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
K663_07770	ENOG4107QX3	carboxylase
K663_07775	ENOG4105CFF	transcriptional regulator
K663_07790	ENOG4107QP8	phosphohexose isomerase
K663_07795	ENOG4105C3F	Signal peptidase i
K663_07805	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
K663_07815	ENOG4105C79	DNA protecting protein DprA
K663_07830	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
K663_07835	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
K663_07865	ENOG4105E3Q	saccharopine dehydrogenase
K663_07885	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
K663_07895	ENOG4105C01	Dihydroxy-acid dehydratase
K663_07905	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
K663_07915	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
K663_07925	ENOG4107SC1	transglycosylase
K663_07930	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
K663_07940	ENOG4105C0B	DNA polymerase III (alpha subunit)
K663_07945	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
K663_07950	ENOG4105D60	lipoprotein releasing system transmembrane protein
K663_07955	ENOG4108ZNX	Heat shock protein
K663_07960	ENOG4105DFH	Transport of potassium into the cell (By similarity)
K663_07970	ENOG4105KWW	Biogenesis protein
K663_07975	ENOG4107QX9	Thiol disulfide interChange protein
K663_07980	ENOG4105DA4	cytochrome c-type biogenesis protein
K663_07985	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
K663_07995	ENOG41060IM	Heme exporter protein
K663_08000	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
K663_08005	ENOG4105PDP	Short chain dehydrogenase
K663_08010	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
K663_08015	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
K663_08020	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
K663_08035	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
K663_08045	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
K663_08055	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
K663_08060	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
K663_08065	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
K663_08080	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
K663_08085	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
K663_08090	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
K663_08095	ENOG4105MH3	Protein of unknown function (DUF2490)
K663_08100	ENOG4105C3G	gtp-binding protein
K663_08110	ENOG4108ZMQ	domain protein
K663_08120	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
K663_08160	ENOG4105CJ1	ABC, transporter
K663_08165	ENOG4107QWP	ABC-2 type transporter
K663_08170	ENOG4107QWP	ABC-2 type transporter
K663_08175	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
K663_08330	ENOG4105VJY	transcriptional regulator
K663_08335	ENOG4105CMI	transporter
K663_08340	ENOG4105CJ1	ABC, transporter
K663_08345	ENOG4105D0S	secretion protein (HlyD
K663_08360	ENOG4108IUZ	ABC transporter
K663_08365	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
K663_08380	ENOG4105HDD	phospholipase
K663_08400	ENOG4107RZC	phospholipase d
K663_08460	ENOG4105ECM	Sensor protein basS pmrB
K663_08505	ENOG41089UC	methyltransferase, type 11
K663_08510	ENOG4108VCT	Sulfite exporter TauE/SafE
K663_08520	ENOG4105D3R	alkyl hydroperoxide reductase
K663_08525	ENOG4105K63	Thioredoxin
K663_08530	ENOG4105D3R	alkyl hydroperoxide reductase
K663_08535	ENOG41080HT	Transcriptional regulator, arsr family
K663_08545	ENOG4105CY0	Metallo-Beta-Lactamase
K663_08560	ENOG4108JJ8	(ABC) transporter
K663_08565	ENOG4108JJ9	ABC, transporter
K663_08570	ENOG4105C4M	(Ubiquinol oxidase) subunit I
K663_08575	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
K663_08600	ENOG4105D6Z	AFG1 family ATPase
K663_08610	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
K663_08620	ENOG4105CHH	sulfate transporter
K663_08625	ENOG4105CHU	acetyl-coa acetyltransferase
K663_08635	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
K663_08640	ENOG4108VKM	cytochrome b561
K663_08650	ENOG41080HT	Transcriptional regulator, arsr family
K663_08655	ENOG4105BZS	acriflavin resistance protein
K663_08670	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
K663_08715	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
K663_08720	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
K663_08750	ENOG4108ZXC	Two component transcriptional regulator, luxr family
K663_08755	ENOG4105BZU	Histidine kinase
K663_08760	ENOG4105VN1	Heat shock protein
K663_08770	ENOG4105NHS	Transcriptional regulator, TraR DksA family
K663_08780	ENOG4105E2V	Glycosyltransferase 36
K663_08790	ENOG4105D5G	Transposase
K663_08955	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
K663_09020	ENOG4105YAJ	CopG Arc MetJ
K663_09025	ENOG4105KRP	Plasmid stabilization system
K663_09085	ENOG4105FA0	parb-like partition protein
K663_09145	ENOG4105CNM	Receptor
K663_09160	ENOG4105DFH	Transport of potassium into the cell (By similarity)
K663_09170	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
K663_09175	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
K663_09180	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
K663_09185	ENOG4105C08	Histidine kinase
K663_09270	ENOG4105K64	Glycosyl transferase, family 2
K663_09275	ENOG4105JEU	Glycosyl transferase, family 2
K663_09305	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
K663_09310	ENOG4108I62	cina-like protein
K663_09315	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
K663_09320	ENOG4108YZA	Nitrogen regulatory protein pii
K663_09325	ENOG4105C5F	glutamine synthetase
K663_09350	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
K663_09355	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
K663_09360	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
K663_09365	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
K663_09370	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
K663_09390	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
K663_09400	ENOG4105CSM	endonuclease III
K663_09425	ENOG4105D9P	serine threonine protein kinase
K663_09430	ENOG4105D9P	serine threonine protein kinase
K663_09440	ENOG4105F9F	transposase
K663_09535	ENOG4105E4C	Lytic transglycosylase catalytic
K663_09625	ENOG4107ZSV	Receptor
K663_09720	ENOG4106NZI	LysR family Transcriptional regulator
K663_09725	ENOG4105C01	Dihydroxy-acid dehydratase
K663_09740	ENOG4107RAN	Peptidase, M16
K663_09745	ENOG4105C1J	atp-dependent rna helicase
K663_09755	ENOG41083MR	nifu domain-containing protein
K663_09760	ENOG41072GX	Peptidase M22 Glycoprotease
K663_09765	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
K663_09770	ENOG4108YXV	Transcriptional regulator
K663_09775	ENOG41090R7	Ferric uptake
K663_09785	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
K663_09795	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
K663_09800	ENOG4107RCQ	(CBS) domain
K663_09820	ENOG410841Q	phosphoesterase PA-phosphatase related protein
K663_09845	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
K663_09850	ENOG4108RPX	mosc domain containing protein
K663_09860	ENOG4105BZF	Glycosyl transferase (Group 1
K663_09865	ENOG4105D1H	recombination factor protein RarA
K663_09875	ENOG4105E39	Enoyl-CoA hydratase
K663_09880	ENOG410642E	Short chain dehydrogenase
K663_09885	ENOG4105EUJ	GTP cyclohydrolase i
K663_09895	ENOG4107SFI	Major Facilitator superfamily
K663_09900	ENOG4105CHU	acetyl-coa acetyltransferase
K663_09905	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
K663_09915	ENOG4108UIN	ybak prolyl-trna synthetase associated region
K663_09920	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
K663_09930	ENOG4105CIH	Imidazole acetol-phosphate transaminase
K663_09960	ENOG4108Z0R	Transferase
K663_09965	ENOG4105D52	delta-aminolevulinic acid dehydratase
K663_09985	ENOG4105HHA	aminodeoxychorismate lyase
K663_09990	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
K663_10000	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
K663_10010	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
K663_10025	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
K663_10030	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
K663_10040	ENOG4105BZU	Histidine kinase
K663_10045	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
K663_10065	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
K663_10075	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
K663_10080	ENOG4108VRQ	UPF0314 protein
K663_10090	ENOG4105C9Q	fumarate hydratase class II
K663_10100	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
K663_10110	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
K663_10115	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
K663_10120	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
K663_10130	ENOG4105DGU	Histone deacetylase
K663_10135	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
K663_10160	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
K663_10170	ENOG41082CG	Protein CrcB homolog
K663_10190	ENOG4105CD3	dihydroorotase
K663_10195	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
K663_10220	ENOG4105CKW	Inner membrane protein yedI
K663_10225	ENOG4107QI1	Mate efflux family protein
K663_10235	ENOG4105E3A	(ABC) transporter
K663_10240	ENOG4105DA5	(ABC) transporter
K663_10290	ENOG4105P8F	nudix hydrolase
K663_10295	ENOG4105DJ0	Poly(A) Polymerase
K663_10305	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
K663_10315	ENOG4105BZP	glycoside hydrolase 15-related
K663_10330	ENOG4107QPR	SAICAR synthetase
K663_10340	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
K663_10345	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
K663_10430	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
K663_10435	ENOG4105DQ4	alcohol dehydrogenase
K663_10440	ENOG4105DQ4	alcohol dehydrogenase
K663_10445	ENOG4108733	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
K663_10450	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
K663_10455	ENOG4105VD1	ATP synthase subunit C
K663_10460	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
K663_10475	ENOG410689M	(LipO)protein
K663_10485	ENOG4105W5Q	DNA repair protein (RadC
K663_10500	ENOG4105CQB	FAD linked oxidase domain protein
K663_10515	ENOG4107ZSV	Receptor
K663_10530	ENOG4105CHR	reductase
K663_10550	ENOG4105D64	Mechanosensitive ion channel
K663_10575	ENOG4108RTD	type II secretion system protein K
K663_10580	ENOG4108WWZ	General secretion pathway protein J
K663_10585	ENOG4105X5Z	General secretion pathway protein I
K663_10595	ENOG4108VAU	general secretion pathway protein G
K663_10600	ENOG4105D7Q	type ii secretion system
K663_10605	ENOG4107QHF	type ii secretion system protein e
K663_10650	ENOG4105DDQ	anthranilate synthase
K663_10655	ENOG4108I0Q	anthranilate phosphoribosyltransferase
K663_10660	ENOG4105DK0	Indole-3-glycerol phosphate synthase
K663_10665	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
K663_10670	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
K663_10675	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
K663_10680	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
K663_10685	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
K663_10690	ENOG4105BZN	citrate synthase
K663_10695	ENOG4105BZU	Histidine kinase
K663_10725	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
K663_10750	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
K663_10755	ENOG4105E3A	(ABC) transporter
K663_10765	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
K663_10775	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
K663_10785	ENOG4108JJA	ABC, transporter
K663_10790	ENOG4105DFG	type I secretion outer membrane protein
K663_10815	ENOG4105NWN	ApaG protein
K663_10825	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
K663_10830	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
K663_10840	ENOG4105WH1	Two component transcriptional regulator luxr family
K663_10855	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
K663_10860	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
K663_10865	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
K663_10870	ENOG4105C8S	subunit m
K663_10875	ENOG4105D65	subunit l
K663_10880	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
K663_10885	ENOG4105DF2	NADH dehydrogenase subunit j
K663_10890	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
K663_10895	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
K663_10900	ENOG4107R0R	NADH dehydrogenase subunit g
K663_10905	ENOG4107QIZ	NADH dehydrogenase
K663_10915	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
K663_10920	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
K663_10925	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
K663_10930	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
K663_10935	ENOG4105ECY	inositol monophosphatase
K663_10940	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
K663_10945	ENOG4108K5P	(LipO)protein
K663_10950	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
K663_10955	ENOG4106HMZ	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
K663_10970	ENOG4105WYW	fructose-bisphosphate aldolase
K663_10975	ENOG4105BZA	Phosphoglycerate kinase
K663_10985	ENOG4105CV1	Transketolase (EC 2.2.1.1)
K663_11000	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
K663_11010	ENOG4105DSF	transport protein
K663_11020	ENOG4107QSN	dihydrolipoamide acetyltransferase
K663_11025	ENOG4105CPP	Dehydrogenase, E1 component
K663_11035	ENOG4107R0V	Pyruvate dehydrogenase
K663_11040	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
K663_11050	ENOG4105C83	adenylosuccinate lyase
K663_11060	ENOG4105DQE	DNA ligase
K663_11065	ENOG4105FDF	Could be involved in DNA repair (By similarity)
K663_11075	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
K663_11090	ENOG4105CFU	surface antigen
K663_11115	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K663_11130	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
K663_11135	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
K663_11140	ENOG4107SVH	Potassium channel protein
K663_11145	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
K663_11160	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
K663_11175	ENOG4107SQ0	N-acetyl-gamma-glutamyl-phosphate reductase
K663_11200	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
K663_11210	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
K663_11215	ENOG4105CEY	Amp-dependent synthetase and ligase
K663_11255	ENOG4105HFZ	Membrane
K663_11260	ENOG41081HM	2'-5' rna ligase
K663_11265	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
K663_11370	ENOG4105K5X	acetyltransferase
K663_11400	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
K663_11405	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
K663_11410	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
K663_11415	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
K663_11490	ENOG4105C10	Electron transfer flavoprotein
K663_11495	ENOG4105BZJ	Electron transfer flavoprotein
K663_11500	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
K663_11515	ENOG410802X	bacteriophage n4 adsorption protein b
K663_11675	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
K663_11700	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
K663_11810	ENOG410802X	bacteriophage n4 adsorption protein b
K663_11835	ENOG4105CXT	aspartate transcarbamylase
K663_11840	ENOG4105CD3	dihydroorotase
K663_11850	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
K663_11855	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
K663_11860	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
K663_11870	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
K663_11875	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
K663_11880	ENOG4105K46	50S ribosomal protein l27
K663_11890	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
K663_11895	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
K663_11940	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
K663_11945	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
K663_11955	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
K663_11960	ENOG4105EAH	synthase
K663_11970	ENOG4105CQ7	ATP-dependent helicase
K663_11985	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
K663_12005	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K663_12010	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K663_12015	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
K663_12020	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
K663_12035	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
K663_12040	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
K663_12045	ENOG4108UFP	Essential cell division protein (By similarity)
K663_12050	ENOG4105CPF	Cell wall formation (By similarity)
K663_12055	ENOG4105D4A	Cell wall formation (By similarity)
K663_12060	ENOG4105DFU	Cell wall formation (By similarity)
K663_12075	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
K663_12080	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
K663_12105	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
K663_12125	ENOG4105C6T	cysteine synthase
K663_12140	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
K663_12145	ENOG41081BE	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
K663_12150	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
K663_12155	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
K663_12160	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
K663_12175	ENOG4105C75	arginyL-tRNA synthetase
K663_12185	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
K663_12195	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
K663_12265	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
K663_12275	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
K663_12285	ENOG4105EEI	dihydropteroate synthase
K663_12290	ENOG4105CEC	DNA methylase N-4 N-6
K663_12295	ENOG41082SX	arsR family transcriptional regulator
K663_12300	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
K663_12305	ENOG4105D3R	alkyl hydroperoxide reductase
K663_12310	ENOG4108JU3	Alkyl hydroperoxide reductase
K663_12320	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
K663_12325	ENOG4105DWF	phosphomethylpyrimidine kinase
K663_12330	ENOG4105XDF	Protein of unknown function (DUF1272)
K663_12335	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
K663_12340	ENOG4105BZG	amino acid carrier protein
K663_12350	ENOG4108UJD	30S ribosomal protein S9
K663_12355	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
K663_12360	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
K663_12365	ENOG4105BZU	Histidine kinase
K663_12385	ENOG4107T65	Integrase
K663_12390	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
K663_12445	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
K663_12450	ENOG4105FAW	cDP-glucose 4,6-dehydratase
K663_12455	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
K663_12465	ENOG4105C7K	acetolactate synthase
K663_12470	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
K663_12480	ENOG4105CKK	Glycosyl transferase, family 2
K663_12530	ENOG4105FA0	parb-like partition protein
K663_12570	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
K663_12640	ENOG4105EUJ	GTP cyclohydrolase i
K663_12730	ENOG4105C2X	Arabinose 5-phosphate isomerase
K663_12735	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
K663_12740	ENOG4105C2X	Arabinose 5-phosphate isomerase
K663_12750	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
K663_12785	ENOG4105KAK	Plasmid pRiA4b ORF-3 family protein
K663_12790	ENOG4105E5H	Transposase
K663_12795	ENOG4108YXQ	IS66 Orf2 family protein
K663_12805	ENOG4105CMM	transposase
K663_12915	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
K663_12945	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
K663_12950	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
K663_12960	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
K663_12965	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
K663_12975	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
K663_12980	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
K663_12995	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
K663_13010	ENOG4107RJX	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
K663_13015	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
K663_13025	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
K663_13030	ENOG4105DBV	ornithine carbamoyltransferase
K663_13035	ENOG4105C8Y	Acetylornithine aminotransferase
K663_13045	ENOG4105DTS	flagellar hook-associated
K663_13055	ENOG4105D00	flagellar biosynthetic protein flhB
K663_13060	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
K663_13065	ENOG4105VS8	Flagellar biosynthetic protein fliq
K663_13070	ENOG4105CN7	Flagellar biosynthetic protein FliP
K663_13080	ENOG4105DD5	Flagellar motor switch protein
K663_13105	ENOG4108JIR	Flagellum-specific ATP synthase
K663_13115	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
K663_13120	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
K663_13125	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
K663_13130	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
K663_13145	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
K663_13150	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
K663_13155	ENOG4105D7B	Flagellar biosynthesis protein flha
K663_13185	ENOG4105E14	MotA TolQ exbB proton channel
K663_13190	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
K663_13195	ENOG4108ZC9	flagellar basal-body rod protein flgc
K663_13200	ENOG410822I	Flagellar hook capping protein
K663_13205	ENOG4105CGA	flagellar basal-body rod protein FlgG
K663_13210	ENOG4108KPB	Flagellar basal-body rod protein FlgF
K663_13215	ENOG4105CGA	flagellar basal-body rod protein FlgG
K663_13225	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
K663_13245	ENOG4107RD7	Flagellar Motor Protein, MotA
K663_13250	ENOG4105ER2	Ompa motb domain protein
K663_13265	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
K663_13280	ENOG4105C8Q	Methyl-accepting chemotaxis
K663_13310	ENOG4105YK5	50S ribosomal protein L36
K663_13320	ENOG4105CA9	Pyruvate kinase
K663_13340	ENOG4105K8R	UPF0145 protein
K663_13345	ENOG4105CDY	transcriptional regulatory protein
K663_13350	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
K663_13370	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
K663_13375	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
K663_13385	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
K663_13390	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
K663_13400	ENOG4105CSA	Coproporphyrinogen iii oxidase
K663_13420	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
K663_13425	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
K663_13460	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
K663_13465	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
K663_13480	ENOG4107T5V	SNARE associated Golgi
K663_13485	ENOG4105D7Z	glutathione synthase
K663_13495	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
K663_13505	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
K663_13510	ENOG4105EHG	Permease protein
K663_13525	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
K663_13530	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
K663_13545	ENOG4108IFG	nitrite reductase, (NAD(P)H)
K663_13555	ENOG4105I5W	Transporter
K663_13570	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
K663_13575	ENOG4105CW7	secretion protein, HlyD family
K663_13580	ENOG4105ETP	RND efflux system, outer membrane lipoprotein
K663_13590	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
K663_13600	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
K663_13615	ENOG4105CH7	arginosuccinase
K663_13620	ENOG4107ZT5	Thiol disulfide interchange protein
K663_13630	ENOG4105W49	UPF0434 protein
K663_13635	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
K663_13640	ENOG4105K63	Thioredoxin
K663_13660	ENOG4105CQC	Prephenate dehydratase
K663_13665	ENOG4105G9V	cytochrome C
K663_13675	ENOG4105CDV	Ompa motb domain protein
K663_13690	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
K663_13700	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
K663_13705	ENOG410856B	UPF0235 protein
K663_13715	ENOG4105CAS	nag kinase
K663_13720	ENOG4105C9X	ppx gppa phosphatase
K663_13725	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
K663_13740	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
K663_13745	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
K663_13750	ENOG4105DA5	(ABC) transporter
K663_13760	ENOG4108IYU	L-aspartate oxidase
K663_13765	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
K663_13775	ENOG4105C3R	Methionine synthase
K663_13780	ENOG4105C3R	Methionine synthase
K663_13785	ENOG4105SYT	Methylenetetrahydrofolate reductase
K663_13810	ENOG4105KDC	50s ribosomal protein l28
K663_13820	ENOG4108Z6B	deaminase
K663_13835	ENOG4108NEV	two component transcriptional regulator, LytTR family
K663_13840	ENOG4108HRK	Histidine kinase
K663_13845	ENOG4105KVH	Transcriptional regulator
K663_13855	ENOG4108VZM	50s ribosomal protein L10
K663_13860	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
K663_13865	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
K663_13880	ENOG4105DZ0	fad dependent oxidoreductase
K663_13900	ENOG4105CSU	acyl-Coa dehydrogenase
K663_13905	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
K663_13910	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
K663_13920	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
K663_13925	ENOG4105K5M	30s ribosomal protein S16
K663_13930	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K663_13945	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
K663_13950	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
K663_13955	ENOG4107835	probably involved in intracellular septation (By similarity)
K663_13980	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
K663_13985	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
K663_13990	ENOG4105BZU	Histidine kinase
K663_13995	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
K663_14010	ENOG4105CBS	Chea signal transduction histidine kinase
K663_14020	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
K663_14030	ENOG4105HA9	of methanol dehydrogenase type
K663_14040	ENOG4108YZ4	nudix hydrolase
K663_14075	ENOG41084CK	capsule polysaccharide
K663_14080	ENOG4105E12	capsule polysaccharide
K663_14090	ENOG4105K59	histidine triad (HIT) protein
K663_14105	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
K663_14110	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
K663_14115	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
K663_14120	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
K663_14145	ENOG4105C2M	dna polymerase I
K663_14150	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
K663_14160	ENOG4105HFZ	Membrane
K663_14165	ENOG4105C8N	cysteinyl-tRNA synthetase
K663_14175	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
K663_14195	ENOG4107RCI	amp-dependent synthetase and ligase
K663_14220	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
K663_14230	ENOG4105CFG	Acts as a chaperone (By similarity)
K663_14250	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
K663_14260	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
K663_14265	ENOG4105BZU	Histidine kinase
K663_14275	ENOG4105CA3	membrane-bound lytic murein transglycosylase
K663_14285	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
K663_14295	ENOG4105C31	Tryptophanyl-tRNA synthetase
K663_14305	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
K663_14310	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
K663_14315	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
K663_14320	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
K663_14330	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
K663_14335	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
K663_14340	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
K663_14345	ENOG4105D06	uba thif-type nad fad binding protein
K663_14355	ENOG4105C22	threonyL-tRNA synthetase
K663_14375	ENOG4105CHM	Aminotransferase
K663_14380	ENOG4105CM2	brancheD-chain amino acid aminotransferase
K663_14405	ENOG4105F4G	Membrane
K663_14425	ENOG4105D3Q	Sugar transferase
K663_14430	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
K663_14460	ENOG4107STW	synthase
K663_14470	ENOG4108KMV	Glycosyl transferase (Group 1
K663_14475	ENOG4107TAE	Glycosyl transferase (Group 1
K663_14505	ENOG4105WH1	Two component transcriptional regulator luxr family
K663_14545	ENOG4105Z4T	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
K663_14550	ENOG4105BZ9	Cytochrome C oxidase, subunit I
K663_14560	ENOG4105CCU	oxidase (Subunit III)
K663_14570	ENOG4105G9V	cytochrome C
K663_14580	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
K663_14665	ENOG4105BZU	Histidine kinase
K663_14670	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
K663_14680	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
K663_14685	ENOG4108302	MgtC SapB transporter
K663_14690	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
K663_14695	ENOG4105CVJ	phosphoglycerate mutase
K663_14835	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
K663_14845	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
K663_14915	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
K663_14955	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
K663_14975	ENOG4105C0B	DNA polymerase III (alpha subunit)
K663_14980	ENOG4107F83	nucleotidyltransferase DNA polymerase involved in DNA
K663_15015	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
K663_15020	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
K663_15025	ENOG4105E4C	Lytic transglycosylase catalytic
K663_15030	ENOG4108RRZ	Transcription elongation factor GreB
K663_15035	ENOG4105CN1	protease
K663_15045	ENOG4105C8Q	Methyl-accepting chemotaxis
K663_15050	ENOG4105CSR	polyphosphate kinase 2
K663_15060	ENOG4105C9M	aspartyl-trna synthetase
K663_15065	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
K663_15085	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
K663_15100	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
K663_15105	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
K663_15110	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
K663_15115	ENOG41084HQ	50S ribosomal protein L30
K663_15120	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
K663_15125	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
K663_15130	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
K663_15135	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
K663_15140	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
K663_15145	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
K663_15150	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
K663_15155	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
K663_15160	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
K663_15170	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
K663_15175	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
K663_15180	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
K663_15185	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
K663_15190	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
K663_15195	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
K663_15200	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
K663_15205	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
K663_15210	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
K663_15215	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
K663_15220	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
K663_15225	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
K663_15230	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
K663_15235	ENOG4105BZU	Histidine kinase
K663_15240	ENOG4105DR5	peptidase
K663_15245	ENOG4105C0P	Mg chelatase subunit ChlI
K663_15250	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
K663_15265	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
K663_15290	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
K663_15295	ENOG4105CHH	sulfate transporter
K663_15320	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
K663_15340	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
K663_15350	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
K663_15355	ENOG4108ZT0	50S ribosomal protein l17
K663_15400	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
K663_15450	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
K663_15465	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
K663_15485	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
K663_15490	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
K663_15500	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
K663_15510	ENOG4105BZU	Histidine kinase
K663_15520	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
K663_15525	ENOG4105D0A	hydroxylase
K663_15530	ENOG4105CM2	brancheD-chain amino acid aminotransferase
K663_15555	ENOG4108Z4V	iron-sulfur cluster assembly
K663_15560	ENOG4105VG1	fes assembly suf system protein
K663_15565	ENOG4105C9B	Cysteine desulfurase
K663_15570	ENOG4105JRK	feS assembly protein SufD
K663_15575	ENOG4105C3K	feS assembly ATPase SufC
K663_15600	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
K663_15605	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
K663_15635	ENOG41087YS	Phage shock protein A
K663_15640	ENOG4105E51	psp operon transcriptional activator
K663_15645	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
K663_15650	ENOG4107YD3	Thioesterase
K663_15655	ENOG4105E02	MotA TolQ exbB proton channel
K663_15660	ENOG4105SG9	biopolymer transport protein, ExbD
K663_15670	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
K663_15675	ENOG4105KCK	Peptidoglycan-associated lipoprotein
K663_15680	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
K663_15700	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
K663_15705	ENOG4105D05	Receptor
K663_15715	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
K663_15720	ENOG4105C12	Phosphoribosylglycinamide synthetase
K663_15725	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
K663_15735	ENOG4105ECY	inositol monophosphatase
K663_15740	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
K663_15750	ENOG4105CEN	a g-specific adenine glycosylase
K663_15770	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
K663_15775	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
K663_15790	ENOG4105D1K	glutamate--cysteine ligase
K663_15800	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
K663_15805	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
K663_15820	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
K663_15825	ENOG4105C0F	tryptophanase EC 4.1.99.1
K663_15840	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
K663_15925	ENOG4105KAK	Plasmid pRiA4b ORF-3 family protein
K663_15930	ENOG4105E5H	Transposase
K663_15935	ENOG4108YXQ	IS66 Orf2 family protein
K663_15950	ENOG4105CMM	transposase
K663_15955	ENOG4107ZSV	Receptor
K663_15985	ENOG4105CHR	reductase
K663_15990	ENOG4105ERH	Fumarylacetoacetate hydrolase
K663_16000	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
K663_16015	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
K663_16020	ENOG4105CHR	reductase
K663_16050	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
K663_16055	ENOG4105CHR	reductase
K663_16060	ENOG410846T	CoA-transferase family III
K663_16065	ENOG4105C1G	acyl-Coa dehydrogenase
K663_16070	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
K663_16075	ENOG4105CHU	acetyl-coa acetyltransferase
K663_16095	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
K663_16115	ENOG4105NNS	Autoinducer synthesis protein
K663_16150	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
K663_16200	ENOG4105FA0	parb-like partition protein
K663_16235	ENOG4105E4C	Lytic transglycosylase catalytic
K663_16270	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
K663_16295	ENOG4105DDW	LysR family Transcriptional regulator
K663_16300	ENOG4105EXG	Transcriptional regulator
K663_16315	ENOG4107ZSV	Receptor
K663_16325	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
K663_16330	ENOG4105E6M	Sulphatase-modifying factor protein
K663_16345	ENOG4107ZSV	Receptor
K663_16350	ENOG4105M2Z	protein tyrosine serine phosphatase
K663_16360	ENOG4105WH1	Two component transcriptional regulator luxr family
K663_16400	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
K663_16405	ENOG4105EIH	LPPG Fo 2-phospho-L-lactate transferase
K663_16410	ENOG4105ME0	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor (By similarity)
K663_16415	ENOG4105C6K	Malic enzyme
K663_16420	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
K663_16425	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
K663_16435	ENOG4107QJN	gtp cyclohydrolase ii
K663_16450	ENOG4105CNU	cell division protein FtsK
K663_16465	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
K663_16480	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
K663_16485	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
K663_16490	ENOG4108YXA	Membrane
K663_16495	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
K663_16606	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
K663_16626	ENOG4105CQZ	Histidine kinase
K663_16641	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
K663_16651	ENOG4108T5G	Adenylate
K663_16716	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
K663_16721	ENOG4106FI7	cytochrome c-type biogenesis protein
K663_16726	ENOG4105VC4	domain protein
K663_16781	ENOG4105CQZ	Histidine kinase
K663_16801	ENOG4105EJC	lysr family transcriptional regulator
K663_16811	ENOG4105KJF	protein tyrosine phosphatase
K663_16821	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
K663_16836	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
K663_16841	ENOG4105CJW	magnesium transporter
K663_16851	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
K663_16856	ENOG4108IUZ	ABC transporter
K663_16861	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
K663_16876	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
K663_16881	ENOG4108UKI	Enoyl-CoA hydratase
K663_16891	ENOG4105CEV	competence damage-inducible protein
K663_16896	ENOG4108DWA	Nad synthetase
K663_16901	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
K663_16906	ENOG4107U9T	Pfam:Ribonuclease_BN
K663_16916	ENOG4105D4P	Coproporphyrinogen iii oxidase
K663_16936	ENOG4105BZU	Histidine kinase
K663_16941	ENOG4108ZXC	Two component transcriptional regulator, luxr family
K663_16946	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
K663_16966	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
K663_17006	ENOG4105DGW	oligopeptidase A
K663_17026	ENOG4105P52	geranylgeranyl reductase
K663_17041	ENOG4105C26	Dehydrogenase
K663_17051	ENOG4108UKI	Enoyl-CoA hydratase
K663_17061	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
K663_17071	ENOG4105CPC	Aldo Keto reductase
K663_17076	ENOG4108J2R	molybdopterin oxidoreductase
K663_17091	ENOG4105CXG	d-lactate dehydrogenase
K663_17146	ENOG4107ZSV	Receptor
K663_17151	ENOG4108UKI	Enoyl-CoA hydratase
K663_17161	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
K663_17166	ENOG4105C7S	Dehydrogenase
K663_17186	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
K663_17191	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
K663_17201	ENOG4105CPQ	Dehydrogenase
K663_17211	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
K663_17236	ENOG4105C1G	acyl-Coa dehydrogenase
K663_17251	ENOG4106A3M	Cytochrome p-450
K663_17256	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
K663_17266	ENOG4105F2C	Acetyl-CoA acetyltransferase
K663_17271	ENOG4105C1G	acyl-Coa dehydrogenase
K663_17286	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
K663_17296	ENOG4108IG5	Transcriptional regulator
K663_17301	ENOG4105Q56	cytochrome P450
K663_17306	ENOG4105FUY	alpha subunit
K663_17326	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
K663_17351	ENOG41060WC	Enoyl-CoA hydratase
K663_17406	ENOG4105DVW	rieske (2Fe-2S)
K663_17411	ENOG4105CHR	reductase
K663_17431	ENOG4105CEY	Amp-dependent synthetase and ligase
K663_17436	ENOG4105CEY	Amp-dependent synthetase and ligase
K663_17501	ENOG4105CC9	acyl-Coa dehydrogenase
K663_17506	ENOG4105C1G	acyl-Coa dehydrogenase
K663_17511	ENOG4105CHR	reductase
K663_17526	ENOG4108X07	Tetr family transcriptional regulator
K663_17536	ENOG4105C7S	Dehydrogenase
K663_17561	ENOG4105M2Z	protein tyrosine serine phosphatase
K663_17576	ENOG4105FUY	alpha subunit
K663_17581	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
K663_17621	ENOG4105CIR	epoxide hydrolase
K663_17636	ENOG4105DVW	rieske (2Fe-2S)
K663_17666	ENOG4105E1F	short-chain dehydrogenase reductase
K663_17676	ENOG4105C1G	acyl-Coa dehydrogenase
K663_17681	ENOG4107RUY	(E1 component), alpha subunit
K663_17686	ENOG4105CPP	Dehydrogenase, E1 component
K663_17691	ENOG4105E39	Enoyl-CoA hydratase
K663_17696	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
K663_17706	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
K663_17716	ENOG4105FUY	alpha subunit
K663_17731	ENOG4105CYM	Glutathione S-transferase
K663_17746	ENOG4105CHR	reductase
K663_17761	ENOG4105CIR	epoxide hydrolase
K663_17771	ENOG4105CK5	oxidoreductase
K663_17781	ENOG4105D05	Receptor
K663_17801	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
K663_17806	ENOG4105CI2	imidazolone-5-propionate hydrolase
K663_17811	ENOG4107ZSV	Receptor
K663_17851	ENOG4105CHR	reductase
K663_17866	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
K663_17896	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
K663_17926	ENOG4105DVW	rieske (2Fe-2S)
K663_17931	ENOG4107EFR	Flavocytochrome c
K663_17961	ENOG4108R85	Short chain dehydrogenase
K663_17971	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
K663_17986	ENOG4107S2E	monooxygenase
K663_17991	ENOG4107ZSV	Receptor
K663_18011	ENOG4107ZSV	Receptor
K663_18016	ENOG4105DVW	rieske (2Fe-2S)
K663_18026	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
K663_18036	ENOG4105CHR	reductase
K663_18046	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
K663_18056	ENOG4106A3M	Cytochrome p-450
K663_18081	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
K663_18091	ENOG4105CHR	reductase
K663_18096	ENOG4107RUY	(E1 component), alpha subunit
K663_18116	ENOG4108R85	Short chain dehydrogenase
K663_18126	ENOG4108KEZ	Dehydrogenase
K663_18146	ENOG4107ZSV	Receptor
K663_18161	ENOG4105D94	Major Facilitator Superfamily
K663_18171	ENOG4105EMU	Dehydrogenase
K663_18201	ENOG4105DU1	integral membrane protein, terc
K663_18206	ENOG4105BZU	Histidine kinase
K663_18211	ENOG4105BZU	Histidine kinase
K663_18216	ENOG410903D	sensor protein
K663_18226	ENOG41063JG	Transcriptional regulator
K663_18236	ENOG41090HR	transcriptional regulator
K663_18246	ENOG4108RM3	Phosphatase with a broad specificity. Its primary physiological function is to dephosphorylate 3'-phosphoadenosine 5'-phosphate (PAP) and 3'-phosphoadenosine 5'-phosphosulfate (PAPS). Thus, plays a role in mycobacterial sulfur metabolism, since it can serve as a key regulator of the sulfate assimilation pathway by controlling the pools of PAP and PAPS in the cell. To a lesser extent, is also able to hydrolyze inositol 1-phosphate (I- 1-P), fructose 1,6-bisphosphate (FBP) (to fructose 6-phosphate (F- 6-P)) and AMP in vitro, but this might has no significance in vivo
K663_18256	ENOG4105C11	sulfate adenylyltransferase), subunit 2
K663_18271	ENOG4105E39	Enoyl-CoA hydratase
K663_18276	ENOG4105DHU	Bile acid
K663_18286	ENOG4105K70	DNA-binding protein
K663_18291	ENOG4108YXV	Transcriptional regulator
K663_18306	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
K663_18311	ENOG4105W8H	transhydrogenase (subunit alpha
K663_18316	ENOG4108YZT	Adenosylcobinamide kinase
K663_18321	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
K663_18331	ENOG4108374	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
K663_18341	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
K663_18351	ENOG4105CG3	alpha amylase, catalytic region
K663_18356	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
K663_18386	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
K663_18411	ENOG4105QUC	reductase
K663_18426	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
K663_18431	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
K663_18446	ENOG4105ED1	spovr family
K663_18451	ENOG4106AKX	UPF0229 protein
K663_18456	ENOG4105CYN	Serine protein kinase
K663_18541	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
K663_18546	ENOG4105MIR	Phenylalanine 4-monooxygenase
K663_18551	ENOG4108XM1	transcriptional regulator AsnC family
K663_18571	ENOG4105EZE	Cupin 4 family protein
K663_18576	ENOG4108R99	pseudouridine synthase
K663_18596	ENOG4105CFG	Acts as a chaperone (By similarity)
K663_18611	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
K663_18676	ENOG4105CFF	transcriptional regulator
K663_18686	ENOG4107RET	Isocitrate lyase
K663_18691	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
K663_18696	ENOG4105E0K	tonB-dependent siderophore receptor
K663_18746	ENOG4105D1Q	UPF0246 protein
K663_18766	ENOG4105K4T	epimerase
K663_18791	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
K663_18796	ENOG4105E0C	molybdate abc transporter
K663_18801	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
K663_18806	ENOG4105E0F	Histidine kinase
K663_18811	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
K663_18816	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
K663_18821	ENOG4105BZS	acriflavin resistance protein
K663_18826	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
K663_18871	ENOG4105C26	Dehydrogenase
K663_18881	ENOG4108I0Y	(ABC) transporter
K663_18886	ENOG4108UJV	acyl-CoA thioesterase i
K663_18891	ENOG4108UPT	UPF0178 protein
K663_18906	ENOG4107QIZ	NADH dehydrogenase
K663_18911	ENOG4108JB9	formate dehydrogenase
K663_18936	ENOG4108JPW	Aminotransferase
K663_18941	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
K663_18946	ENOG4105EV8	ectoine hydroxylase
K663_18951	ENOG4105CZK	Aspartate kinase
K663_18961	ENOG4105CSH	Transporter
K663_18966	ENOG4105CUY	Mechanosensitive ion channel
K663_19001	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
K663_19016	ENOG4105CHH	sulfate transporter
K663_19041	ENOG4108VCT	Sulfite exporter TauE/SafE
K663_19046	ENOG4105C4M	(Ubiquinol oxidase) subunit I
K663_19051	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
K663_19056	ENOG4105D65	subunit l
K663_19061	ENOG4108ZE9	Monovalent cation H antiporter subunit C
K663_19066	ENOG4107R4Z	monovalent cation h antiporter subunit d
K663_19076	ENOG4105W4C	monovalent cation H antiporter subunit F
K663_19086	ENOG4108U51	Universal stress protein
K663_19091	ENOG4105CNI	cell division protein FtsW
K663_19111	ENOG4108U51	Universal stress protein
K663_19131	ENOG4105M2Z	protein tyrosine serine phosphatase
K663_19161	ENOG4107SET	aldo keto reductase
K663_19166	ENOG4108Q9H	CobQ/CobB/MinD/ParA nucleotide binding domain
K663_19171	ENOG4106JGA	Chromosome (Plasmid) partitioning protein, ParB
K663_19253	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
K663_19263	ENOG4107SJW	iron permease, FTR1
K663_19338	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
K663_19383	ENOG4105C26	Dehydrogenase
K663_19393	ENOG4105E3B	Multicopper oxidase
K663_19408	ENOG4108ZXC	Two component transcriptional regulator, luxr family
K663_19413	ENOG4108ZXC	Two component transcriptional regulator, luxr family
K663_19418	ENOG4105BZU	Histidine kinase
K663_19433	ENOG4105E3B	Multicopper oxidase
K663_19468	ENOG4108Z6Z	Transcriptional regulator
K663_19498	ENOG4105CEP	NADH dehydrogenase
K663_19518	ENOG4105BZU	Histidine kinase
K663_19533	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
K663_19583	ENOG41069FQ	Metallo-beta-lactamase superfamily
K663_19613	ENOG4105D1Q	UPF0246 protein
K663_19618	ENOG4108YXV	Transcriptional regulator
K663_19633	ENOG4108R99	pseudouridine synthase
K663_19638	ENOG4105EZE	Cupin 4 family protein
K663_19713	ENOG4107HP6	Transcriptional regulator
K663_19718	ENOG4105CHU	acetyl-coa acetyltransferase
K663_19733	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
K663_19748	ENOG4105EA8	2-Nitropropane dioxygenase
K663_19753	ENOG4107ZSV	Receptor
K663_19788	ENOG4107ZSV	Receptor
K663_19813	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
K663_19848	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
K663_19863	ENOG4105CHF	Glutathione S-transferase
K663_19893	ENOG41064T2	transcriptional regulator, lysR family
K663_19898	ENOG4107RQ0	Maleylacetate reductase
K663_19913	ENOG4108K3A	Glutathione S-transferase
K663_19938	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
K663_19953	ENOG4107ZSV	Receptor
K663_19973	ENOG4108C33	Resolvase
K663_19993	ENOG4107ZSV	Receptor
K663_20003	ENOG4108K3A	Glutathione S-transferase
K663_20018	ENOG4107RQ0	Maleylacetate reductase
K663_20088	ENOG4108C33	Resolvase
K663_20098	ENOG4108KDQ	Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons (By similarity)
K663_20123	ENOG4105C0B	DNA polymerase III (alpha subunit)
K663_20138	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
K663_20143	ENOG4105E39	Enoyl-CoA hydratase
K663_20148	ENOG4108UKI	Enoyl-CoA hydratase
K663_20153	ENOG4105C1G	acyl-Coa dehydrogenase
K663_20158	ENOG4105C26	Dehydrogenase
K663_20163	ENOG4105JQN	Transcriptional regulator
K663_20203	ENOG4105K70	DNA-binding protein
K663_20208	ENOG4105E4C	Lytic transglycosylase catalytic
K663_20418	ENOG4105DVW	rieske (2Fe-2S)
K663_20438	ENOG41076PI	Short-chain dehydrogenase reductase Sdr
K663_20443	ENOG4105CHR	reductase
K663_20453	ENOG4108UKI	Enoyl-CoA hydratase
K663_20463	ENOG4105CEY	Amp-dependent synthetase and ligase
K663_20478	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
K663_20488	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
K663_20493	ENOG4105VQD	rieske 2fe-2S domain-containing protein
K663_20528	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
K663_20533	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
K663_20543	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
K663_20553	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
K663_20558	ENOG4106A3M	Cytochrome p-450
K663_20593	ENOG4107ZSV	Receptor
K663_20613	ENOG4105JBR	DNA replication protein
K663_20638	ENOG4105EE5	Membrane protein terC
K663_20783	ENOG4105D5G	Transposase
K663_20823	ENOG4105ZGE	Toxic component of a toxin-antitoxin (TA) module. A
K663_20838	ENOG4105BZS	acriflavin resistance protein
K663_20863	ENOG4108YXV	Transcriptional regulator
K663_20868	ENOG4105W5Q	DNA repair protein (RadC
K663_20883	ENOG4105PFC	Transcriptional regulator
K663_20888	ENOG4107RBR	Receptor
K663_21078	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
K663_21083	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
K663_21093	ENOG4105P0T	Usg family
K663_21103	ENOG4105VN1	Heat shock protein
K663_21108	ENOG4108ZNX	Heat shock protein
K663_21288	ENOG4105CC0	LysR family Transcriptional regulator
K663_21293	ENOG4105CS1	NAD(P)H quinone oxidoreductase
K663_21303	ENOG4105NN7	muconolactone delta-isomerase
K663_21349	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
K663_21388	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
K663_21428	ENOG4105D6J	arsenicaL-resistance protein
K663_21448	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
K663_21453	ENOG4105D0S	secretion protein (HlyD
K663_21458	ENOG4105CJ1	ABC, transporter
K663_21463	ENOG4107QWP	ABC-2 type transporter
K663_21468	ENOG4107QWP	ABC-2 type transporter
K663_21503	ENOG4105ECM	Sensor protein basS pmrB
K663_21563	ENOG4105EQR	Transposase IS116 IS110 IS902
K663_21608	ENOG4105EKQ	RNA-directed DNA polymerase
K663_21618	ENOG4105C6T	cysteine synthase
K663_21653	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
K663_21698	ENOG4107VRP	DNA repair exonuclease
K663_21703	ENOG4106D4I	domain protein
K663_21778	ENOG4108C33	Resolvase
K663_21783	ENOG4107FW0	short-chain dehydrogenase reductase
K663_21923	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
K663_21958	ENOG4108C33	Resolvase
K663_21968	ENOG4105DC8	reductase
K663_21973	ENOG4108K3A	Glutathione S-transferase
K663_21988	ENOG4105CYM	Glutathione S-transferase
K663_22023	ENOG4107QNJ	CoA-transferase subunit B
K663_22043	ENOG4105CYM	Glutathione S-transferase
K663_22053	ENOG4108XFH	Transcriptional regulator
K663_22058	ENOG4105CYM	Glutathione S-transferase
K663_22078	ENOG4105MP0	transposase
K663_22173	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
K663_22208	ENOG4107XAN	XdhC and CoxI family
K663_22213	ENOG4105CNM	Receptor
K663_22223	ENOG4105CPP	Dehydrogenase, E1 component
K663_22228	ENOG4107RUY	(E1 component), alpha subunit
K663_22233	ENOG4105CEY	Amp-dependent synthetase and ligase
K663_22238	ENOG41082JN	Transcriptional regulator
K663_22243	ENOG4107U2T	alpha beta
K663_22248	ENOG4105CHR	reductase
K663_22408	ENOG4107RQ0	Maleylacetate reductase
K663_22423	ENOG4108K3A	Glutathione S-transferase
K663_22458	ENOG4108C33	Resolvase
K663_22473	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
K663_22553	ENOG4108C33	Resolvase
K663_22598	ENOG4108C33	Resolvase
K663_22613	ENOG4108C33	Resolvase
K663_22623	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
K663_22628	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
K663_22633	ENOG4105ESI	atpase involved in dna repair
K663_22648	ENOG41082AG	Plasmid maintenance system antidote protein
K663_22693	ENOG4108UUM	single-stranded DNA-binding protein
K663_22708	ENOG4107QJE	Chromosome Partitioning Protein
K663_22713	ENOG4105FA0	parb-like partition protein
K663_22743	ENOG4108EHY	type IV secretion system
K663_22748	ENOG4105CMA	conjugation trbi family protein
K663_22753	ENOG4105EGP	transfer protein
K663_22758	ENOG4108V42	Type IV secretion system protein VirB8
K663_22823	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
K663_22968	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
K663_22978	ENOG4107ZSV	Receptor
K663_23003	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)