locus-tag	class	description
SHELI_v1c00040	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
SHELI_v1c00080	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
SHELI_v1c00110	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
SHELI_v1c00140	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
SHELI_v1c00230	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
SHELI_v1c00240	ENOG41087V7	Binds to the 23S rRNA (By similarity)
SHELI_v1c00390	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
SHELI_v1c00480	ENOG41082SK	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
SHELI_v1c00580	ENOG4108YZG	isomerase
SHELI_v1c00740	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
SHELI_v1c00800	ENOG4107UZ6	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)
SHELI_v1c00820	ENOG4105C3M	thioredoxin reductase
SHELI_v1c00980	ENOG4107TH2	purine nucleoside phosphorylase
SHELI_v1c00990	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
SHELI_v1c01650	ENOG41072GX	Peptidase M22 Glycoprotease
SHELI_v1c01870	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
SHELI_v1c02040	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
SHELI_v1c02050	ENOG4105VJV	50s ribosomal protein L35
SHELI_v1c02100	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
SHELI_v1c02180	ENOG4107YHV	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
SHELI_v1c02230	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
SHELI_v1c02260	ENOG4105X36	(ribosomal) protein
SHELI_v1c02300	ENOG4105II7	pyrroline-5-carboxylate reductase
SHELI_v1c02360	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
SHELI_v1c02420	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
SHELI_v1c02430	ENOG4105FE9	pseudouridine synthase
SHELI_v1c02450	ENOG4105CDY	transcriptional regulatory protein
SHELI_v1c02540	ENOG4105DFF	Rod shape-determining protein mreb
SHELI_v1c02590	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
SHELI_v1c02600	ENOG410841J	DNA-binding protein Hu
SHELI_v1c02620	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
SHELI_v1c02640	ENOG4105CEV	competence damage-inducible protein
SHELI_v1c02750	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SHELI_v1c02780	ENOG41082VF	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
SHELI_v1c02930	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
SHELI_v1c03070	ENOG4107ZRJ	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SHELI_v1c03290	ENOG4107S0N	DJ-1 family
SHELI_v1c03360	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
SHELI_v1c03520	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
SHELI_v1c04820	ENOG4105DVE	abc transporter atp-binding protein
SHELI_v1c04830	ENOG4105DVE	abc transporter atp-binding protein
SHELI_v1c04930	ENOG4105E98	transcriptional regulator DeoR family
SHELI_v1c05960	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
SHELI_v1c06050	ENOG4105EE0	oxidoreductase
SHELI_v1c06140	ENOG4105DBI	uridine monophosphokinase
SHELI_v1c06330	ENOG4105E98	transcriptional regulator DeoR family
SHELI_v1c06400	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
SHELI_v1c06680	ENOG410687G	Involved in DNA repair and RecF pathway recombination (By similarity)
SHELI_v1c06860	ENOG4107ARW	50S ribosomal protein L33
SHELI_v1c06990	ENOG41068RJ	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
SHELI_v1c07050	ENOG4105C34	Pseudouridine synthase
SHELI_v1c07200	ENOG4108439	Cell division protein mraZ
SHELI_v1c07220	ENOG41082GS	50S ribosomal protein L32
SHELI_v1c07330	ENOG4108RWN	rrna methyltransferase
SHELI_v1c07380	ENOG41060GV	RNA binding s1 domain protein
SHELI_v1c07390	ENOG41083MR	nifu domain-containing protein
SHELI_v1c07440	ENOG4105JRK	feS assembly protein SufD
SHELI_v1c07650	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
SHELI_v1c07830	ENOG4106H78	methyltransferase
SHELI_v1c08120	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
SHELI_v1c08160	ENOG4107IQ5	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
SHELI_v1c08290	ENOG4105C6N	Formate acetyltransferase
SHELI_v1c08320	ENOG4108UJD	30S ribosomal protein S9
SHELI_v1c08510	ENOG41067V7	50S ribosomal protein L36
SHELI_v1c08520	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
SHELI_v1c08570	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
SHELI_v1c08580	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
SHELI_v1c08590	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
SHELI_v1c08620	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SHELI_v1c08690	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
SHELI_v1c08720	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
SHELI_v1c08740	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
SHELI_v1c08750	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
SHELI_v1c08860	ENOG4105DKW	ABC transporter
SHELI_v1c09480	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
SHELI_v1c09560	ENOG4108RVA	ribokinase
SHELI_v1c09590	ENOG4105C2J	ABC transporter
SHELI_v1c09600	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
SHELI_v1c10730	ENOG4108KP7	hydrolase
SHELI_v1c11060	ENOG41082EV	50s ribosomal protein l31
SHELI_v1c11200	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
SHELI_v1c11240	ENOG4105FA0	parb-like partition protein
SHELI_v1c11250	ENOG4107QJE	Chromosome Partitioning Protein
SHELI_v1c11320	ENOG4107XRV	hypoxanthine phosphoribosyltransferase
SHELI_v1c11350	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
SHELI_v1c11360	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
SHELI_v1c11410	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
SHELI_v1c11580	ENOG4108585	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)