locus-tag class description DQU53_00090 ENOG4108U7W acetyltransferase DQU53_00105 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) DQU53_00120 ENOG4105EWM Histidine kinase DQU53_00175 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) DQU53_00180 ENOG410848D S4 domain protein YaaA DQU53_00190 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DQU53_00195 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DQU53_00200 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) DQU53_00230 ENOG4105DWV Homoserine O-trans-acetylase DQU53_00240 ENOG4105BZR domain protein DQU53_00250 ENOG4105CDU Replicative dna helicase DQU53_00260 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis DQU53_00295 ENOG4105Q2H domain protein DQU53_00300 ENOG4105CGH 5'-nucleotidase DQU53_00310 ENOG4105DZR Type I site-specific deoxyribonuclease DQU53_00325 ENOG4108HK0 -acetyltransferase DQU53_00360 ENOG4107Y5K Resolvase DQU53_00385 ENOG4105KTU Transcriptional regulator, arsr family DQU53_00395 ENOG4105C59 p-type ATPase DQU53_00455 ENOG4105C2M dna polymerase I DQU53_00495 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase DQU53_00505 ENOG4108QXE glycerophosphoryl diester phosphodiesterase DQU53_00510 ENOG4108ZMQ domain protein DQU53_00515 ENOG4107RVG penicillin-binding protein DQU53_00520 ENOG4105CCN Peptidase M56 DQU53_00545 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) DQU53_00550 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase DQU53_00555 ENOG4105XTG Pfam:DUF156 DQU53_00560 ENOG41087NI Sulfite exporter TauE/SafE DQU53_00570 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) DQU53_00585 ENOG41071EZ rRNA adenine N-6-methyltransferase DQU53_00590 ENOG4106JUT Streptomycin 3''-adenylyltransferase DQU53_00595 ENOG4105ZX1 Transposase C DQU53_00600 ENOG4108KU9 integrase family DQU53_00605 ENOG4108FPN Integrase DQU53_00610 ENOG410826E Dna repair protein radc DQU53_00665 ENOG4105EEX Two component transcriptional regulator (Winged helix family DQU53_00670 ENOG4105C08 Histidine kinase DQU53_00680 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) DQU53_00685 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) DQU53_00690 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) DQU53_00745 ENOG41087NI Sulfite exporter TauE/SafE DQU53_00750 ENOG4105XTG Pfam:DUF156 DQU53_00755 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase DQU53_00760 ENOG4105C5X domain protein DQU53_00780 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) DQU53_00855 ENOG4105C57 major facilitator superfamily DQU53_00865 ENOG4105CCI Myosin-Cross-Reactive Antigen DQU53_00870 ENOG4107Y9U Membrane DQU53_00905 ENOG4108IHU transport system permease protein DQU53_00910 ENOG4105DQ5 transport system permease protein DQU53_00915 ENOG4108MES Periplasmic binding protein DQU53_00925 ENOG4105CIF Ornithine Cyclodeaminase DQU53_00930 ENOG4105DJU Siderophore biosynthesis protein DQU53_00935 ENOG4105C6X Major Facilitator DQU53_00940 ENOG4105DBM Siderophore biosynthesis protein DQU53_00945 ENOG4105DUU IucA IucC family protein DQU53_00955 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) DQU53_00960 ENOG41067FT ParB-like nuclease domain DQU53_00975 ENOG4105CHR reductase DQU53_00985 ENOG4108IAJ Nad-dependent epimerase dehydratase DQU53_00995 ENOG4105CPK Glycosyl transferase (Group 1 DQU53_01030 ENOG4105D3A purine nucleoside phosphorylase DeoD-type DQU53_01035 ENOG4108J8C transporter major facilitator family protein DQU53_01040 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) DQU53_01075 ENOG4105CGH 5'-nucleotidase DQU53_01090 ENOG4108EKI Dehydrogenase DQU53_01115 ENOG4105C5E polysaccharide biosynthesis protein DQU53_01125 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase DQU53_01155 ENOG4105D3Q Sugar transferase DQU53_01170 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase DQU53_01180 ENOG4105WD1 Membrane DQU53_01185 ENOG4105C26 Dehydrogenase DQU53_01190 ENOG4105PGM cation diffusion facilitator family transporter DQU53_01220 ENOG4105C1G acyl-Coa dehydrogenase DQU53_01225 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) DQU53_01260 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) DQU53_01270 ENOG4105C8Y Acetylornithine aminotransferase DQU53_01275 ENOG4105CWM branched-chain amino acid transport system II carrier protein DQU53_01280 ENOG4105D3W isochorismatase DQU53_01285 ENOG4107RA9 decarboxylase DQU53_01315 ENOG4105QEK Transcriptional regulator DQU53_01325 ENOG4105DZR Type I site-specific deoxyribonuclease DQU53_01340 ENOG4105C19 ABC transporter DQU53_01345 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) DQU53_01365 ENOG4105DA5 (ABC) transporter DQU53_01380 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component DQU53_01385 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DQU53_01395 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) DQU53_01430 ENOG4105EG2 ABC transporter, permease DQU53_01440 ENOG4105CK5 oxidoreductase DQU53_01450 ENOG4108WWS isoprenylcysteine carboxyl methyltransferase DQU53_01455 ENOG4105CXY transporter DQU53_01505 ENOG4105CHU acetyl-coa acetyltransferase DQU53_01510 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase DQU53_01515 ENOG4105C1G acyl-Coa dehydrogenase DQU53_01520 ENOG4105CEY Amp-dependent synthetase and ligase DQU53_01525 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) DQU53_01535 ENOG4107RRN ABC transporter substrate-binding protein DQU53_01540 ENOG4105K78 MarR family Transcriptional regulator DQU53_01575 ENOG4105CI1 PTS System DQU53_01580 ENOG4105DU0 nucleoside hydrolase DQU53_01600 ENOG4105K18 The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) DQU53_01605 ENOG4105DT3 PTS system, galactitol-specific IIc component DQU53_01610 ENOG4105CPQ Dehydrogenase DQU53_01620 ENOG4105CPQ Dehydrogenase DQU53_01625 ENOG4108QHG Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) DQU53_01630 ENOG4105EJJ Dehydrogenase DQU53_01635 ENOG4107RZX Teichoic acid biosynthesis protein DQU53_01640 ENOG4107SJB teichoic acid biosynthesis DQU53_01650 ENOG4105EJJ Dehydrogenase DQU53_01655 ENOG4107RZX Teichoic acid biosynthesis protein DQU53_01700 ENOG4105CI1 PTS System DQU53_01705 ENOG4105CS2 ec 3.2.1.21 DQU53_01715 ENOG4105DVA methyltransferase DQU53_01735 ENOG4105EV1 Ribose uptake protein RbsU DQU53_01765 ENOG4105DR5 peptidase DQU53_01770 ENOG4105DA5 (ABC) transporter DQU53_01790 ENOG4105VRS hydrolase family 18 DQU53_01800 ENOG4106PAW secretion accessory protein EsaA YueB DQU53_01810 ENOG4106GSS Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host. Negative regulator of EsaC, which is a secretion substrate of the Ess pathway in many Staphylococcus strains. Not necessary for the production and secretion of EsxA or EsxB (By similarity) DQU53_01820 ENOG4105EC2 ftsk spoIIIe DQU53_01920 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family DQU53_01930 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) DQU53_01960 ENOG4105D9N nucleoside DQU53_01965 ENOG4107RJ1 sodium solute DQU53_01975 ENOG41061DF Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity) DQU53_01980 ENOG4106KNT transcriptional regulator DQU53_01990 ENOG4105DWD nucleoside recognition domain protein DQU53_01995 ENOG4105J1V Triacylglycerol lipase DQU53_02015 ENOG4105DEN Luciferase family DQU53_02025 ENOG4108UVJ appr-1-p processing domain protein DQU53_02040 ENOG4105CMR udp-glucose 4-epimerase DQU53_02045 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC DQU53_02055 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia DQU53_02060 ENOG4105CID antiterminator DQU53_02075 ENOG4105C3S Mate efflux family protein DQU53_02085 ENOG4105CXY transporter DQU53_02100 ENOG4107V0Z fmn reductase DQU53_02120 ENOG410650H (LipO)protein DQU53_02125 ENOG4105DBE peroxidase DQU53_02130 ENOG4107SJW iron permease, FTR1 DQU53_02135 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) DQU53_02140 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) DQU53_02150 ENOG4105VZ8 Transcriptional regulator DQU53_02160 ENOG4105CJ1 ABC, transporter DQU53_02175 ENOG4105CHU acetyl-coa acetyltransferase DQU53_02195 ENOG4105C28 cystathionine DQU53_02200 ENOG4105C28 cystathionine DQU53_02210 ENOG4105FA0 parb-like partition protein DQU53_02215 ENOG4105D8X mechanosensitive ion channel DQU53_02220 ENOG4105VDK protein, conserved in bacteria DQU53_02225 ENOG4105C3G gtp-binding protein DQU53_02245 ENOG4108UUM single-stranded DNA-binding protein DQU53_02315 ENOG4108JU3 Alkyl hydroperoxide reductase DQU53_02325 ENOG4108DBC nitroreductase DQU53_02330 ENOG4107R6U sodium dicarboxylate symporter DQU53_02365 ENOG4105C2W permease DQU53_02405 ENOG4105KA3 membrAne DQU53_02565 ENOG4105CKI cobalamin synthesis protein DQU53_02590 ENOG4108TWJ NADH dehydrogenase subunit 5 DQU53_02600 ENOG4105GPN Uncharacterized conserved protein (DUF2294) DQU53_02620 ENOG4105C8J )-transporter DQU53_02630 ENOG4105C28 cystathionine DQU53_02635 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) DQU53_02640 ENOG4108UMI ABC transporter, permease DQU53_02645 ENOG4105D01 (LipO)protein DQU53_02680 ENOG4105C5Q Transcriptional regulator DQU53_02685 ENOG4105CBC glutamate synthase DQU53_02690 ENOG4105BZ8 glutamate synthase DQU53_02700 ENOG4105C5Y PTS System DQU53_02705 ENOG4105CG3 alpha amylase, catalytic region DQU53_02710 ENOG4107414 GntR family transcriptional regulator DQU53_02730 ENOG4105C6E dna polymerase iii DQU53_02735 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) DQU53_02770 ENOG4105CXN decarboxylase DQU53_02780 ENOG4105X0R protein from nitrogen regulatory protein P-II DQU53_02785 ENOG4105FA2 dna polymerase iii DQU53_02790 ENOG4105MA4 psp1 domain protein DQU53_02800 ENOG41060K3 Methyltransferase DQU53_02810 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) DQU53_02815 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) DQU53_02820 ENOG4105F8V Hydrolase, tatD family DQU53_02825 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) DQU53_02835 ENOG4105W42 Veg protein DQU53_02845 ENOG4105DFT pur operon repressor DQU53_02850 ENOG4105KME endoribonuclease L-psp DQU53_02865 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) DQU53_02870 ENOG4105C5T Phosphoribosyl pyrophosphate synthase DQU53_02890 ENOG4108JA2 transcriptioN-repair coupling factor DQU53_02900 ENOG4108IY2 MazG family DQU53_02905 ENOG41082I2 s4 domain protein DQU53_02915 ENOG41060GV RNA binding s1 domain protein DQU53_02920 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) DQU53_02925 ENOG4108UGV hypoxanthine phosphoribosyltransferase DQU53_02930 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) DQU53_02940 ENOG4105C6T cysteine synthase DQU53_02945 ENOG4105EEI dihydropteroate synthase DQU53_02950 ENOG4105KRF dihydroneopterin aldolase DQU53_02955 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase DQU53_03045 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DQU53_03060 ENOG4105D9N nucleoside DQU53_03070 ENOG4108Z0C Uvrb UvrC protein DQU53_03085 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) DQU53_03090 ENOG4105CTP PilT protein domain protein DQU53_03115 ENOG4105KEB Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) DQU53_03120 ENOG4105C2N RNA methyltransferase TrmH family group 3 DQU53_03140 ENOG410683Z Preprotein translocase SecE subunit DQU53_03145 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) DQU53_03175 ENOG4107Y49 methyltransferase DQU53_03185 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) DQU53_03220 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) DQU53_03240 ENOG4105CM2 brancheD-chain amino acid aminotransferase DQU53_03245 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase DQU53_03250 ENOG4105ZMH deoxynucleoside kinase DQU53_03260 ENOG4108Z6B deaminase DQU53_03265 ENOG410667J hydrolase DQU53_03280 ENOG4105DUY Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein DQU53_03285 ENOG4105DUY Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein DQU53_03310 ENOG4107YEI lmbE family DQU53_03325 ENOG4108VA3 3-hexulose-6-phosphate synthase DQU53_03375 ENOG4105DWF phosphomethylpyrimidine kinase DQU53_03420 ENOG4108IJ2 phosphate acetyltransferase DQU53_03425 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) DQU53_03430 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) DQU53_03450 ENOG4107QN2 dihydrolipoyl dehydrogenase DQU53_03485 ENOG4105CPC Aldo Keto reductase DQU53_03495 ENOG4108WS4 fmn reductase DQU53_03505 ENOG4105DCI Phosphohydrolase DQU53_03510 ENOG4108XFG YwhD family DQU53_03540 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) DQU53_03545 ENOG4108IU2 vtamin B12-transporter permease DQU53_03555 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) DQU53_03595 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off DQU53_03635 ENOG4105EEQ Na H antiporter DQU53_03650 ENOG4105DSE periplasmic solute binding protein DQU53_03655 ENOG4105CC5 ABC transporter DQU53_03660 ENOG4105DIK (ABC) transporter DQU53_03665 ENOG4107R5H iron (metal) dependent repressor, dtxr family DQU53_03675 ENOG4108UHC Glycosyl transferase, wecb taga cpsf family DQU53_03680 ENOG4105EY8 ABC transporter DQU53_03700 ENOG4107YSK Glycerol-3-phosphate cytidylyltransferase DQU53_03710 ENOG4105BZ1 (ABC) transporter DQU53_03725 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) DQU53_03730 ENOG4105E0A ABC, transporter DQU53_03735 ENOG4105DQ5 transport system permease protein DQU53_03740 ENOG4105EHG Permease protein DQU53_03745 ENOG4105CMT Dihydroxyacetone kinase DQU53_03755 ENOG4105VDH Dihydroxyacetone kinase DQU53_03765 ENOG4108K88 Membrane DQU53_03805 ENOG4105C19 ABC transporter DQU53_03820 ENOG4107GRR phosphate transport regulator DQU53_03825 ENOG4105CJ3 phosphate transporter DQU53_03830 ENOG4105VRS hydrolase family 18 DQU53_03840 ENOG4105ID8 Transcriptional regulator, ARAC family DQU53_03875 ENOG4105S8Q sugar efflux transporter DQU53_03880 ENOG4105SXS Protein of unknown function (DUF456) DQU53_03905 ENOG4108YYQ gCN5-related N-acetyltransferase DQU53_03910 ENOG4108URH decarboxylase DQU53_03930 ENOG4108JJ9 ABC, transporter DQU53_03935 ENOG4108JJ8 (ABC) transporter DQU53_03940 ENOG41083AI transcriptional regulator), MarR family DQU53_03945 ENOG4105CKI cobalamin synthesis protein DQU53_03950 ENOG4107QM2 Aldo Keto reductase DQU53_03960 ENOG4107QPK )-transporter DQU53_03965 ENOG4105CVP deoxyribo-dipyrimidine photolyase DQU53_03985 ENOG4105DP8 Major facilitator superfamily MFS_1 DQU53_03995 ENOG4108Z66 YbaK ebsC protein DQU53_04000 ENOG4105E98 transcriptional regulator DeoR family DQU53_04005 ENOG4105DE4 1-phosphofructokinase DQU53_04010 ENOG4105DM4 PTS System DQU53_04015 ENOG4105CE4 GlcNAc 6-P deacetylase DQU53_04020 ENOG4105C37 (CBS) domain DQU53_04030 ENOG4105CKK Glycosyl transferase, family 2 DQU53_04060 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) DQU53_04065 ENOG4107ZAE 6-carboxy-5,6,7,8-tetrahydropterin synthase DQU53_04075 ENOG4105DDQ anthranilate synthase DQU53_04080 ENOG4105CRQ synthase (Component I) DQU53_04110 ENOG4105C5H ABC transporter DQU53_04115 ENOG4105C9U ATP-dependent DNA helicase RecQ DQU53_04120 ENOG4108IJ8 ABC transporter DQU53_04125 ENOG4105E90 ABC transporter DQU53_04135 ENOG4108ZIE 5 nucleotidase deoxy cytosolic type C DQU53_04160 ENOG4105DUX Transporter DQU53_04190 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) DQU53_04195 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) DQU53_04205 ENOG4105DHS permease protein DQU53_04210 ENOG4105CM4 permease protein DQU53_04215 ENOG4108IPW abc transporter atp-binding protein DQU53_04275 ENOG4105ESV Glycosyl transferase, family 4 DQU53_04280 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein DQU53_04295 ENOG41081UC Inherit from COG: Competence protein DQU53_04325 ENOG41068JE domain protein DQU53_04340 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) DQU53_04345 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) DQU53_04360 ENOG4108S4C acetyltransferase DQU53_04370 ENOG4105C3M thioredoxin reductase DQU53_04385 ENOG4105CHW UPF0052 protein DQU53_04430 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase DQU53_04445 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) DQU53_04460 ENOG4105XZU Preprotein translocase, subunit SecG DQU53_04470 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) DQU53_04520 ENOG4106HV3 Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps DQU53_04520 ENOG4106HV3 Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps DQU53_04540 ENOG4107Y9E nuclease DQU53_04545 ENOG4105VEQ Cold shock protein DQU53_04585 ENOG4105CVJ phosphoglycerate mutase DQU53_04590 ENOG4108ZUB Lysine exporter protein (Lyse ygga) DQU53_04615 ENOG4105SZ6 Thioredoxin DQU53_04620 ENOG41080E8 Transcriptional regulator, Spx MgsR family DQU53_04635 ENOG4108XI2 Domain of unknown function (DUF1963) DQU53_04655 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) DQU53_04660 ENOG4108UMI ABC transporter, permease DQU53_04665 ENOG4105D01 (LipO)protein DQU53_04680 ENOG4105C3K feS assembly ATPase SufC DQU53_04685 ENOG4105JRK feS assembly protein SufD DQU53_04690 ENOG4105C9B Cysteine desulfurase DQU53_04695 ENOG4108UNV SUF system FeS assembly protein, NifU family DQU53_04785 ENOG4108UUM single-stranded DNA-binding protein DQU53_04805 ENOG4106CVF DNA replication protein DQU53_04860 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) DQU53_05015 ENOG4108FQ0 the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis DQU53_05035 ENOG4105ZMJ n-acetylmuramoyl-l-alanine amidase DQU53_05090 ENOG4105I3N Conserved Protein DQU53_05110 ENOG4105MMD transcriptional regulator DQU53_05160 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein DQU53_05170 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD DQU53_05175 ENOG41083MR nifu domain-containing protein DQU53_05195 ENOG4108YX9 iron--sulfur cluster insertion protein erpA DQU53_05205 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) DQU53_05215 ENOG4105KA0 thioesterase Superfamily protein DQU53_05270 ENOG41060GV RNA binding s1 domain protein DQU53_05275 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DQU53_05280 ENOG4105C8Y Acetylornithine aminotransferase DQU53_05285 ENOG4105D82 Glutamate dehydrogenase DQU53_05290 ENOG4107VXM glycerophosphoryl diester phosphodiesterase DQU53_05320 ENOG4105C3F Signal peptidase i DQU53_05350 ENOG4108KP7 hydrolase DQU53_05360 ENOG4105EXC Acyl-transferase DQU53_05365 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit DQU53_05375 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) DQU53_05390 ENOG4105KIS phospholipid-binding protein DQU53_05410 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) DQU53_05420 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component DQU53_05425 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DQU53_05435 ENOG4108JQ7 (ABC) transporter DQU53_05445 ENOG4105DEF Extracellular solute-binding protein, family 5 DQU53_05455 ENOG4108JQ7 (ABC) transporter DQU53_05465 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DQU53_05470 ENOG4105C31 Tryptophanyl-tRNA synthetase DQU53_05475 ENOG41090SU Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity) DQU53_05490 ENOG4105DPN Oligoendopeptidase f DQU53_05495 ENOG4105T58 Dithiol-disulfide isomerase DQU53_05500 ENOG4108Z18 K06886 hemoglobin DQU53_05525 ENOG4105EMS pseudouridine synthase DQU53_05530 ENOG4105CJW magnesium transporter DQU53_05545 ENOG4105C02 permease DQU53_05550 ENOG4105BZG amino acid carrier protein DQU53_05565 ENOG4108PK2 permease that is required for glycolipid anchoring of LTA. May facilitate the transport of diglucosyl- diacylglycerol (Glc2-DAG) from the inner to the outer leaflet of the cytoplasmic membrane, delivering Glc2-DAG as a substrate for LTA synthesis, thereby generating glycolipid-anchored LTA. Appears to play an important role in virulence DQU53_05590 ENOG4107TS3 membrane protein, TerC DQU53_05595 ENOG4105C0H protease DQU53_05605 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic DQU53_05620 ENOG4105XVF Competence transcription factor DQU53_05670 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) DQU53_05690 ENOG4108HUF Transporter DQU53_05700 ENOG4105YB8 TM2 domain containing protein DQU53_05705 ENOG41080E2 ribosomal-protein-alanine acetyltransferase DQU53_05710 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase DQU53_05720 ENOG4105E4F Isochorismate synthase DQU53_05730 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) DQU53_05735 ENOG4108IPT Naphthoate synthase DQU53_05750 ENOG4108CHM Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases DQU53_05755 ENOG4105CHM Aminotransferase DQU53_05760 ENOG4108TGC Acyltransferase DQU53_05780 ENOG41082BV acetyltransferase DQU53_05790 ENOG4108KGH TRANSCRIPTIONal DQU53_05795 ENOG4108A04 Beta-lactamase DQU53_05835 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) DQU53_05840 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit DQU53_05850 ENOG4105VR9 phosphoribosylformylglycinamidine synthase DQU53_05855 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I DQU53_05865 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase DQU53_05875 ENOG4108V3E phosphoribosylglycinamide formyltransferase DQU53_05885 ENOG4105C12 Phosphoribosylglycinamide synthetase DQU53_05890 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) DQU53_05895 ENOG4108JJB ABC transporter DQU53_05900 ENOG4105NSK ABC superfamily ATP binding cassette transporter membrane protein DQU53_05925 ENOG4105DR4 Methyltransferase DQU53_05935 ENOG4105KRI phosphocarrier protein (HPr DQU53_05945 ENOG41067VN Glutaredoxin DQU53_05960 ENOG4107ZYR domain protein DQU53_05980 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) DQU53_05990 ENOG4107RUY (E1 component), alpha subunit DQU53_05995 ENOG4105CPP Dehydrogenase, E1 component DQU53_06000 ENOG4105C7S Dehydrogenase DQU53_06005 ENOG4107QN2 dihydrolipoyl dehydrogenase DQU53_06025 ENOG4105F38 ABC transporter, permease DQU53_06030 ENOG4105D38 putrescine abc transporter DQU53_06035 ENOG4107RUE extracellular solute-binding protein family 1 DQU53_06060 ENOG4105ECY inositol monophosphatase DQU53_06070 ENOG4105CI3 gtp-binding protein typa DQU53_06090 ENOG4105CNI cell division protein FtsW DQU53_06095 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) DQU53_06145 ENOG4106H78 methyltransferase DQU53_06240 ENOG4108UUM single-stranded DNA-binding protein DQU53_06450 ENOG4108FQ0 the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis DQU53_06470 ENOG4105ZMJ n-acetylmuramoyl-l-alanine amidase DQU53_06515 ENOG4105KFN sortase, SrtB family DQU53_06530 ENOG4108RWN rrna methyltransferase DQU53_06540 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) DQU53_06580 ENOG4105DCG PHP domain protein DQU53_06605 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit DQU53_06615 ENOG4105E33 succinate dehydrogenase DQU53_06625 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) DQU53_06700 ENOG4106UK0 Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity DQU53_06735 ENOG4105DBV ornithine carbamoyltransferase DQU53_06745 ENOG4105CSX c4-dicarboxylate anaerobic carrier DQU53_06805 ENOG41068DC Essential cell division protein (By similarity) DQU53_06810 ENOG4105CJN penicillin-binding protein DQU53_06825 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) DQU53_06830 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) DQU53_06835 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) DQU53_06840 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase DQU53_06845 ENOG4105DFA alanine racemase domain protein DQU53_06855 ENOG41067XK integral membrane protein DQU53_06860 ENOG4105DBK s4 domain protein DQU53_06875 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase DQU53_06895 ENOG4105C34 Pseudouridine synthase DQU53_06915 ENOG4105CD3 dihydroorotase DQU53_06920 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain DQU53_06935 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) DQU53_06950 ENOG4105F23 Fibronectin-binding protein DQU53_06955 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) DQU53_06965 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase DQU53_06970 ENOG4105C25 Primosomal protein n' DQU53_06980 ENOG4105YB8 TM2 domain containing protein DQU53_06985 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) DQU53_06995 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B DQU53_07005 ENOG4108ZF3 Phosphatase DQU53_07015 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) DQU53_07020 ENOG4105DJV ribulose-phosphate 3-epimerase DQU53_07035 ENOG4108ZAA Alkaline-shock protein DQU53_07045 ENOG4105CB5 ATP-dependent DNA helicase recG DQU53_07060 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase DQU53_07065 ENOG4105CHR reductase DQU53_07085 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) DQU53_07090 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) DQU53_07130 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) DQU53_07145 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha DQU53_07155 ENOG4108RMH femAB family DQU53_07160 ENOG4105C79 DNA protecting protein DprA DQU53_07165 ENOG4105C79 DNA protecting protein DprA DQU53_07170 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) DQU53_07230 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) DQU53_07235 ENOG4105KNE Phosphatidate cytidylyltransferase DQU53_07265 ENOG4105CHV Transcription elongation factor NusA DQU53_07270 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination DQU53_07295 ENOG4105DTN riboflavin biosynthesis protein ribF DQU53_07320 ENOG4105CNU cell division protein FtsK DQU53_07325 ENOG4105FDP GntR family transcriptional regulator DQU53_07340 ENOG4108RKS Short-chain dehydrogenase reductase Sdr DQU53_07355 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase DQU53_07360 ENOG4105CEV competence damage-inducible protein DQU53_07380 ENOG4105D48 metallophosphoesterase DQU53_07385 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein DQU53_07390 ENOG4105DQU oxidoreductase, subunit beta DQU53_07425 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator DQU53_07430 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) DQU53_07455 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) DQU53_07460 ENOG4108V06 Glutathione peroxidase DQU53_07465 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) DQU53_07470 ENOG4105CXI aluminum resistance protein DQU53_07475 ENOG4105KV4 Transcriptional regulator DQU53_07480 ENOG4105C5F glutamine synthetase DQU53_07555 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) DQU53_07560 ENOG4108M15 ABC transporter DQU53_07575 ENOG4108S01 response regulator DQU53_07600 ENOG4105CFH Aspartokinase DQU53_07605 ENOG4105D6E homoserine dehydrogenase DQU53_07610 ENOG4108IYI Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) DQU53_07635 ENOG4108IQI permease DQU53_07665 ENOG4105K4I Scp-like extracellular DQU53_07685 ENOG4105CV1 Transketolase (EC 2.2.1.1) DQU53_07720 ENOG4105C94 Transporter DQU53_07730 ENOG4108I0Z Aconitate hydratase DQU53_07760 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DQU53_07765 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DQU53_07795 ENOG4105FF5 Membrane DQU53_07800 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) DQU53_07805 ENOG4108RCF TRANSCRIPTIONal DQU53_07815 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) DQU53_07820 ENOG4105EVN Prephenate dehydrogenase DQU53_07825 ENOG4105DER m42 family DQU53_07830 ENOG4105CRQ synthase (Component I) DQU53_07835 ENOG4105DDQ anthranilate synthase DQU53_07865 ENOG4108RMH femAB family DQU53_07870 ENOG4108TV1 Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity) DQU53_07880 ENOG4108KP7 hydrolase DQU53_07890 ENOG4108JMM (ABC) transporter DQU53_07900 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DQU53_07905 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component DQU53_07920 ENOG4105DPN Oligoendopeptidase f DQU53_07925 ENOG4108UTW Plays a role in the regulation of phosphate uptake DQU53_07935 ENOG4105E2Z phosphate ABC transporter (Permease DQU53_07940 ENOG4105C8U phosphate abc transporter DQU53_07960 ENOG4105C5H ABC transporter DQU53_07970 ENOG4105CFH Aspartokinase DQU53_07975 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) DQU53_08000 ENOG4108XFP Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) DQU53_08005 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) DQU53_08050 ENOG4107T89 von Willebrand factor, type A DQU53_08070 ENOG4105C7S Dehydrogenase DQU53_08100 ENOG410841Q phosphoesterase PA-phosphatase related protein DQU53_08115 ENOG4105CN1 protease DQU53_08125 ENOG4105C5Y PTS System DQU53_08135 ENOG4108FKN Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) DQU53_08145 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) DQU53_08195 ENOG4107R7I amino acid DQU53_08200 ENOG4105C7B Threonine dehydratase DQU53_08215 ENOG410890F Dynamin family DQU53_08230 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) DQU53_08270 ENOG4105BZ4 penicillin-binding protein DQU53_08280 ENOG4105CSM endonuclease III DQU53_08310 ENOG4105CPK Glycosyl transferase (Group 1 DQU53_08315 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase DQU53_08365 ENOG4105EAH synthase DQU53_08385 ENOG4105K70 DNA-binding protein DQU53_08400 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) DQU53_08425 ENOG4105HDK L-asparaginase DQU53_08430 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase DQU53_08440 ENOG4106BU8 elastin-binding protein ebpS DQU53_08445 ENOG4105C9U ATP-dependent DNA helicase RecQ DQU53_08500 ENOG4105ZMJ n-acetylmuramoyl-l-alanine amidase DQU53_08550 ENOG4108FKH Transglycosylase SLT domain DQU53_08600 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) DQU53_08820 ENOG4105BZU Histidine kinase DQU53_08825 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DQU53_08830 ENOG4105FE9 pseudouridine synthase DQU53_08850 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DQU53_08855 ENOG4105I3K Ferric uptake regulator, Fur family DQU53_08860 ENOG4108YZ4 nudix hydrolase DQU53_08865 ENOG4105CPC Aldo Keto reductase DQU53_08875 ENOG4105PDP Short chain dehydrogenase DQU53_08880 ENOG4105II7 pyrroline-5-carboxylate reductase DQU53_08890 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase DQU53_08925 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) DQU53_08930 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) DQU53_08940 ENOG4108QEG Membrane DQU53_08950 ENOG4105C7S Dehydrogenase DQU53_08955 ENOG4105CPP Dehydrogenase, E1 component DQU53_08970 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) DQU53_09000 ENOG4108ZSR alkaline shock protein DQU53_09005 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase DQU53_09020 ENOG4105DC7 peptidase M24 DQU53_09035 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) DQU53_09040 ENOG4105WZW rhodanese family DQU53_09085 ENOG4106855 Competence protein DQU53_09090 ENOG4105D7Q type ii secretion system DQU53_09100 ENOG4105C5X domain protein DQU53_09125 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase DQU53_09135 ENOG4107RF6 penicillin-binding protein DQU53_09145 ENOG4105N80 Ferric uptake regulator, Fur family DQU53_09150 ENOG4105FAV ABC, transporter DQU53_09155 ENOG4105FDK ABC transporter DQU53_09165 ENOG4105C1J atp-dependent rna helicase DQU53_09170 ENOG4105EGD dinuclear metal center protein, YbgI family DQU53_09180 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DQU53_09185 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) DQU53_09215 ENOG4105KG3 cytidine deaminase DQU53_09230 ENOG4105C9A Phoh family DQU53_09245 ENOG4105F7J membrane-bound serine protease DQU53_09255 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) DQU53_09260 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) DQU53_09290 ENOG4105CSA Coproporphyrinogen iii oxidase DQU53_09305 ENOG4105TQK DNA polymerase iii, delta' subunit DQU53_09310 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 DQU53_09315 ENOG4108UK2 deaminase DQU53_09320 ENOG4105BZM domain protein DQU53_09325 ENOG4105DXX methyltransferase DQU53_09330 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) DQU53_09335 ENOG4108WF2 Metal Dependent Phosphohydrolase DQU53_09345 ENOG410812S Rna-binding protein DQU53_09355 ENOG4105CQW ribosome biogenesis GTPase YqeH DQU53_09360 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase DQU53_09400 ENOG4105C5A transporter DQU53_09410 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase DQU53_09415 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein DQU53_09425 ENOG4105P4J Allophanate hydrolase, subunit 1 DQU53_09440 ENOG4105CFP Peptidase U32 DQU53_09445 ENOG4105XYU peptidase (U32 family) DQU53_09475 ENOG4105C7H Helicase, RecD TraA family DQU53_09500 ENOG4105C3J Cysteine desulfurase DQU53_09505 ENOG4105DEN Luciferase family DQU53_09525 ENOG4105D1H recombination factor protein RarA DQU53_09530 ENOG4105CUZ uba thif-type nad fad binding protein DQU53_09575 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) DQU53_09580 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) DQU53_09585 ENOG4105VIE preprotein translocase, subunit YajC DQU53_09625 ENOG4105X36 (ribosomal) protein DQU53_09670 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) DQU53_09685 ENOG41071EZ rRNA adenine N-6-methyltransferase DQU53_09690 ENOG4106JUT Streptomycin 3''-adenylyltransferase DQU53_09695 ENOG4105ZX1 Transposase C DQU53_09700 ENOG4108KU9 integrase family DQU53_09705 ENOG4108FPN Integrase DQU53_09715 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) DQU53_09725 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase DQU53_09735 ENOG4108R3E Dna-3-methyladenine glycosylase i DQU53_09755 ENOG4105D52 delta-aminolevulinic acid dehydratase DQU53_09805 ENOG4105U6W MutT NUDIX family protein DQU53_09830 ENOG4108IQI permease DQU53_09860 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase DQU53_09870 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) DQU53_09875 ENOG4105C2M dna polymerase I DQU53_09885 ENOG4105BZU Histidine kinase DQU53_09890 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DQU53_09900 ENOG4108HMX isocitrate dehydrogenase (NADP) DQU53_09905 ENOG4105BZN citrate synthase DQU53_09910 ENOG4105C85 amino acid DQU53_09935 ENOG4105C6K Malic enzyme DQU53_09940 ENOG4105C0B DNA polymerase III (alpha subunit) DQU53_09945 ENOG4105SFS phosphoesterase RecJ domain protein DQU53_09995 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) DQU53_10000 ENOG4105EJ9 Membrane DQU53_10045 ENOG4108QXE glycerophosphoryl diester phosphodiesterase DQU53_10050 ENOG4108X3M OsmC Ohr family protein DQU53_10055 ENOG4105C5R Aminotransferase DQU53_10060 ENOG4108JQ1 Dehydrogenase DQU53_10080 ENOG4105F6E Acyl-transferase DQU53_10085 ENOG4105C0H protease DQU53_10125 ENOG4105F1V Acetoin utilization protein DQU53_10130 ENOG4105DGU Histone deacetylase DQU53_10135 ENOG4105ETE Transcriptional regulator (LacI family DQU53_10145 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase DQU53_10175 ENOG4108VDD TRNA binding domain protein DQU53_10200 ENOG4105C8F Beta-lactamase domain protein DQU53_10210 ENOG4108V15 phosphotransferase enzyme family DQU53_10215 ENOG4105F0I Aminotransferase DQU53_10240 ENOG4105CBX hi0933 family DQU53_10260 ENOG410605W Major Facilitator DQU53_10265 ENOG4105N5T Radical SAM Protein DQU53_10280 ENOG4105E8V Alpha Beta Hydrolase Fold protein DQU53_10305 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) DQU53_10310 ENOG4108R6K riboflavin synthase, subunit alpha DQU53_10315 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) DQU53_10330 ENOG4107R3E Citrate transporter DQU53_10335 ENOG4108FQ0 the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis DQU53_10365 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) DQU53_10375 ENOG4106A8V Protein CrcB homolog DQU53_10380 ENOG4105WMR Protein CrcB homolog DQU53_10390 ENOG4105CV8 reductase DQU53_10415 ENOG4105E09 nadh pyrophosphatase DQU53_10670 ENOG4105C1Q protoporphyrinogen oxidase DQU53_10705 ENOG4105K59 histidine triad (HIT) protein DQU53_10735 ENOG4107VRP DNA repair exonuclease DQU53_10765 ENOG4105WH1 Two component transcriptional regulator luxr family DQU53_10770 ENOG4105BZU Histidine kinase DQU53_10775 ENOG4108YBP pseudouridine synthase DQU53_10780 ENOG4105C9Q fumarate hydratase class II DQU53_10805 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) DQU53_10810 ENOG4105CDA abc transporter atp-binding protein DQU53_10815 ENOG4105E5Q amino acid AbC transporter DQU53_10980 ENOG4105G5W regulator Fur family DQU53_10985 ENOG4108M3J Dehydrogenase DQU53_10990 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen DQU53_11000 ENOG4107NBY Membrane DQU53_11025 ENOG41067AE Membrane-bound metal-dependent hydrolase DQU53_11040 ENOG4105EY8 ABC transporter DQU53_11075 ENOG4108S4H thioesterase Superfamily protein DQU53_11100 ENOG4107U9T Pfam:Ribonuclease_BN DQU53_11110 ENOG4105ENE Histidine kinase DQU53_11230 ENOG4105C4R Atp-dependent dna helicase DQU53_11240 ENOG4105KGF protein, YerC YecD DQU53_11255 ENOG4107DDB Cysteine protease able to DQU53_11280 ENOG4105DAP Nicotinate phosphoribosyltransferase DQU53_11285 ENOG4107QN4 Catalyzes the production of nitric oxide (By similarity) DQU53_11290 ENOG4105CQC Prephenate dehydratase DQU53_11300 ENOG4105C8P )-transporter DQU53_11325 ENOG4105C26 Dehydrogenase DQU53_11380 ENOG4105CJ1 ABC, transporter DQU53_11395 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family DQU53_11425 ENOG4108QYW Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity) DQU53_11445 ENOG4105CZN Potassium uptake protein DQU53_11505 ENOG4108WCX response regulator DQU53_11530 ENOG4105BZU Histidine kinase DQU53_11540 ENOG4105CUC YeeE YedE family protein DQU53_11550 ENOG4105C5H ABC transporter DQU53_11560 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) DQU53_11570 ENOG410801F ribosomal-protein-alanine acetyltransferase DQU53_11575 ENOG41072GX Peptidase M22 Glycoprotease DQU53_11580 ENOG4105K8N protein family UPF0079, ATPase DQU53_11595 ENOG4105C7K acetolactate synthase DQU53_11615 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) DQU53_11695 ENOG4105WN5 stage II sporulation protein DQU53_11700 ENOG4107SGM protein serine threonine phosphatase DQU53_11720 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) DQU53_11735 ENOG4105CKV Membrane DQU53_11745 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) DQU53_11750 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) DQU53_11755 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) DQU53_11765 ENOG4105C08 Histidine kinase DQU53_11770 ENOG4105EEX Two component transcriptional regulator (Winged helix family DQU53_11790 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) DQU53_11815 ENOG4105VPX protein, conserved in bacteria DQU53_11820 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) DQU53_11865 ENOG4105DWF phosphomethylpyrimidine kinase DQU53_11895 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) DQU53_11955 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase DQU53_11980 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) DQU53_11985 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) DQU53_11995 ENOG4107104 thymidine kinase DQU53_12010 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) DQU53_12030 ENOG4105D2N Aldolase DQU53_12055 ENOG4105HNY Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) DQU53_12085 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) DQU53_12095 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) DQU53_12100 ENOG4105D3A purine nucleoside phosphorylase DeoD-type DQU53_12105 ENOG4108RMU ferritin dps family protein DQU53_12140 ENOG4105PGM cation diffusion facilitator family transporter DQU53_12175 ENOG4105DKW ABC transporter DQU53_12180 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) DQU53_12185 ENOG4105CTS PTS system mannitol-specific DQU53_12190 ENOG4105ETD TRANSCRIPTIONal DQU53_12195 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein DQU53_12220 ENOG4105C8B TIGR00159 family DQU53_12225 ENOG4105CYW agmatinase DQU53_12280 ENOG4105D1F ATP-binding protein DQU53_12300 ENOG4108UT2 hemolysin iii DQU53_12305 ENOG4108MYC UTP-glucose-1-phosphate uridylyltransferase DQU53_12310 ENOG4107K5X Membrane-bound metal-dependent hydrolase DQU53_12320 ENOG4105DWD nucleoside recognition domain protein DQU53_12325 ENOG4108U1V ABC transporter, permease DQU53_12330 ENOG4105DQ5 transport system permease protein DQU53_12335 ENOG4108HUF Transporter DQU53_12345 ENOG4106M28 alanine racemase domain protein DQU53_12355 ENOG4107SFI Major Facilitator superfamily DQU53_12380 ENOG4105C94 Transporter DQU53_12385 ENOG4105CIS alcohol dehydrogenase DQU53_12390 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein DQU53_12405 ENOG4105CK1 PTS System DQU53_12410 ENOG4105VCP PTS System DQU53_12435 ENOG4105E98 transcriptional regulator DeoR family DQU53_12440 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) DQU53_12460 ENOG4105VUF Transcriptional regulator DQU53_12470 ENOG4106AM8 polysaccharide lyase family 8 DQU53_12490 ENOG4107FQX Alpha-acetolactate decarboxylase DQU53_12505 ENOG4107RRE RNA-directed DNA polymerase DQU53_12570 ENOG4108JJB ABC transporter DQU53_12605 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) DQU53_12610 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) DQU53_12725 ENOG4105C7N Xanthine uracil vitamin C permease DQU53_12745 ENOG4105CSC Glucose uptake protein DQU53_12780 ENOG4108TV1 Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity) DQU53_12840 ENOG4108ZAF Molybdopterin DQU53_12845 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein DQU53_12850 ENOG4105CVM Molybdenum cofactor synthesis domain protein DQU53_12860 ENOG4105EPU Molybdenum cofactor synthesis domain protein DQU53_12865 ENOG4105D06 uba thif-type nad fad binding protein DQU53_12870 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) DQU53_12875 ENOG4105E0C molybdate abc transporter DQU53_12880 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein DQU53_12895 ENOG4107ZYJ bioY protein DQU53_12910 ENOG4105FDT acyl-CoA dehydrogenase DQU53_12995 ENOG41068JE domain protein DQU53_13005 ENOG4105DFD Na H antiporter DQU53_13040 ENOG4108FQ0 the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis DQU53_13110 ENOG4107YBY Hydrolase DQU53_13115 ENOG4105C09 Bile acid DQU53_13125 ENOG4105CI1 PTS System DQU53_13130 ENOG4108Q3X Transcriptional regulator DQU53_13150 ENOG4105CYX Short-chain dehydrogenase reductase Sdr DQU53_13155 ENOG4105CH2 amidohydrolase DQU53_13165 ENOG4105CGP Urocanate hydratase DQU53_13170 ENOG4105C5Q Transcriptional regulator DQU53_13190 ENOG4105E66 phosphoriboisomerase A DQU53_13195 ENOG4108RPX mosc domain containing protein DQU53_13215 ENOG4105RHA ABC transporter, permease DQU53_13220 ENOG4108IUX (ABC) transporter DQU53_13225 ENOG4105KAF membrAne DQU53_13245 ENOG4105D6U Sodium Glutamate Symporter DQU53_13255 ENOG4105D7N magnesium and cobalt transport protein CorA DQU53_13280 ENOG4105C0R drug resistance transporter emrb qaca subfamily DQU53_13285 ENOG4105CW7 secretion protein, HlyD family DQU53_13315 ENOG41062A4 Transcriptional regulator DQU53_13325 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) DQU53_13355 ENOG4105DWT malate dehydrogenase (quinone) DQU53_13410 ENOG4105ECB domain protein DQU53_13440 ENOG410606W general stress protein DQU53_13480 ENOG4107TXC Transcriptional regulator DQU53_13510 ENOG4108IUE nitrate reductase beta subunit DQU53_13520 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) DQU53_13525 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit DQU53_13530 ENOG4108IFG nitrite reductase, (NAD(P)H) DQU53_13540 ENOG4108XSB acetyltransferase, (GNAT) family DQU53_13545 ENOG4105TMB Formate nitrite transporter DQU53_13560 ENOG4105DSE periplasmic solute binding protein DQU53_13600 ENOG4105CDA abc transporter atp-binding protein DQU53_13605 ENOG4105DRP amino acid AbC transporter DQU53_13610 ENOG4105EAB amino acid AbC transporter DQU53_13670 ENOG4106XHW Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity) DQU53_13685 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) DQU53_13695 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DQU53_13700 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) DQU53_13715 ENOG4105BZ1 (ABC) transporter DQU53_13740 ENOG4105BZW Glycerate kinase DQU53_13750 ENOG4105C2C drug resistance transporter, Bcr CflA DQU53_13770 ENOG4105C85 amino acid DQU53_13775 ENOG4105EEQ Na H antiporter DQU53_13785 ENOG4105C0X amino acid DQU53_13795 ENOG4105ED2 Beta-lactamase DQU53_13810 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) DQU53_13815 ENOG4105C57 major facilitator superfamily DQU53_13820 ENOG4105R40 Glycine betaine carnitine choline DQU53_13830 ENOG4105E90 ABC transporter DQU53_13850 ENOG4105CZ9 Domain of unknown function (DU1801) DQU53_13860 ENOG4107QTZ amino acid DQU53_13865 ENOG4105EBR Carboxylesterase DQU53_13870 ENOG4105F27 Major Facilitator DQU53_13875 ENOG4105C4B ABC transporter, permease DQU53_13880 ENOG41083J0 (ABC) transporter DQU53_13885 ENOG4105CN9 Peptidase m42 family protein DQU53_13905 ENOG4105PQ4 (LipO)protein DQU53_13910 ENOG4105CBC glutamate synthase DQU53_13965 ENOG4105IGJ Zn-dependent Hydrolase of the beta-lactamase fold protein DQU53_13970 ENOG41061TZ Short-chain dehydrogenase reductase Sdr DQU53_13975 ENOG4105CFC Transporter DQU53_13980 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) DQU53_14075 ENOG4105M6F mutator MutT protein DQU53_14080 ENOG4107QSU Phosphoglucomutase phosphomannomutase alpha beta alpha domain DQU53_14155 ENOG4105CMG Carbohydrate kinase DQU53_14160 ENOG4105G3Z GntR family transcriptional regulator DQU53_14175 ENOG4105NRR Uncharacterized protein conserved in bacteria (DUF2188) DQU53_14185 ENOG4105DJB Major Facilitator Superfamily DQU53_14190 ENOG4107T5V SNARE associated Golgi DQU53_14210 ENOG4105CJ1 ABC, transporter DQU53_14230 ENOG4105FBA Phospholipase Carboxylesterase DQU53_14240 ENOG41090MY MarR family Transcriptional regulator DQU53_14250 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase DQU53_14260 ENOG4105C5I Dehydrogenase DQU53_14265 ENOG4108AZI Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity) DQU53_14270 ENOG4108Z15 abc transporter atp-binding protein DQU53_14275 ENOG4106KKU DQU53_14280 ENOG4108Z6X (sortase) family DQU53_14285 ENOG4108Z7F N-acetyltransferase DQU53_14300 ENOG4105EJQ L-serine dehydratase DQU53_14320 ENOG4108UZ3 Transporter DQU53_14350 ENOG41067MG lrgb family DQU53_14360 ENOG4105CMU LysR family (Transcriptional regulator DQU53_14370 ENOG41068JE domain protein DQU53_14380 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase DQU53_14385 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) DQU53_14390 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit DQU53_14400 ENOG4105CE1 Ferrous iron transport protein b DQU53_14410 ENOG4105EYF MMPL domain protein DQU53_14465 ENOG4105FE1 phytoene synthase DQU53_14470 ENOG41076QQ Glycosyl transferase, family 2 DQU53_14475 ENOG4105EWK phytoene DQU53_14485 ENOG41068JE domain protein DQU53_14490 ENOG4105EXC Acyl-transferase DQU53_14550 ENOG4105CHR reductase DQU53_14575 ENOG4107T5J pyridine nucleotide-disulfide oxidoreductase DQU53_14600 ENOG4105FGM Fructosamine kinase DQU53_14605 ENOG4107QYT Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity) DQU53_14660 ENOG4108NKJ Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) DQU53_14665 ENOG4107FQX Alpha-acetolactate decarboxylase DQU53_14680 ENOG4105CUB amino acid DQU53_14685 ENOG4108JPW Aminotransferase DQU53_14700 ENOG4105DWT malate dehydrogenase (quinone) DQU53_14710 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) DQU53_14730 ENOG4105C26 Dehydrogenase DQU53_14740 ENOG4105TRT Transcriptional regulator DQU53_14745 ENOG4105C94 Transporter DQU53_14760 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) DQU53_14765 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase DQU53_14770 ENOG4105D4T Citrate transporter DQU53_14780 ENOG4108Z73 Siroheme synthase DQU53_14785 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) DQU53_14840 ENOG4105G6Z alkaline phosphatase DQU53_14850 ENOG4108U05 Transcriptional regulator DQU53_14860 ENOG4105T6C Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps DQU53_14870 ENOG4105C5B carbamate kinase DQU53_14880 ENOG4105DBV ornithine carbamoyltransferase DQU53_14920 ENOG4105DM4 PTS System DQU53_14925 ENOG4105DG6 mannose-6-phosphate isomerase DQU53_14935 ENOG4108S4A n-acetylmuramoyl-l-alanine amidase DQU53_14940 ENOG4105WQI isochorismatase DQU53_14965 ENOG4106E62 Accessory Sec system protein Asp3 DQU53_14970 ENOG41089G2 accessory Sec system protein Asp2 DQU53_14975 ENOG4108XJK accessory Sec system protein Asp1 DQU53_14990 ENOG4105EW6 flavin reductase domain protein, FMN-binding DQU53_15010 ENOG4107XC4 flavin reductase domain protein, FMN-binding DQU53_15015 ENOG4108F19 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) DQU53_15035 ENOG4105HTX biosynthesis protein DQU53_15040 ENOG4108IG5 Transcriptional regulator DQU53_15045 ENOG4107QJZ Glycosyl transferase, family 2 DQU53_15055 ENOG4107UVV polysaccharide deacetylase DQU53_15070 ENOG4105J1V Triacylglycerol lipase DQU53_15080 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase DQU53_15095 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) DQU53_15105 ENOG4105CIH Imidazole acetol-phosphate transaminase DQU53_15110 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) DQU53_15190 ENOG4107QPK )-transporter DQU53_15195 ENOG4105FR1 rard protein DQU53_15205 ENOG4105D9G High-affinity DQU53_15220 ENOG4105C19 ABC transporter DQU53_15255 ENOG410636K Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity) DQU53_15305 ENOG4108BUD transposase DQU53_15310 ENOG4108S3A nucleotidyltransferase DQU53_15320 ENOG4108BUD transposase DQU53_15360 ENOG4108S4A n-acetylmuramoyl-l-alanine amidase DQU53_15370 ENOG4105C9U ATP-dependent DNA helicase RecQ DQU53_15390 ENOG4108UUM single-stranded DNA-binding protein DQU53_15435 ENOG4105KEG ribosomal-protein-alanine acetyltransferase