locus-tag	class	description
DD548_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
DD548_00015	ENOG410848D	S4 domain protein YaaA
DD548_00030	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DD548_00035	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
DD548_00065	ENOG4105DWV	Homoserine O-trans-acetylase
DD548_00075	ENOG4105BZR	domain protein
DD548_00085	ENOG4105CDU	Replicative dna helicase
DD548_00095	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
DD548_00130	ENOG4105Q2H	domain protein
DD548_00135	ENOG4105CGH	5'-nucleotidase
DD548_00170	ENOG41087NI	Sulfite exporter TauE/SafE
DD548_00175	ENOG4105XTG	Pfam:DUF156
DD548_00180	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
DD548_00185	ENOG4105C5X	domain protein
DD548_00225	ENOG4108WS4	fmn reductase
DD548_00260	ENOG4108NQ3	Phosphatidylinositol-specific phospholipase C
DD548_00265	ENOG4106QP9	(LipO)protein
DD548_00270	ENOG4106QP9	(LipO)protein
DD548_00275	ENOG4106QP9	(LipO)protein
DD548_00285	ENOG41063ZK	Transcriptional Regulator AraC Family
DD548_00295	ENOG4105C57	major facilitator superfamily
DD548_00305	ENOG4105CCI	Myosin-Cross-Reactive Antigen
DD548_00310	ENOG4107Y9U	Membrane
DD548_00345	ENOG4108IHU	transport system permease protein
DD548_00350	ENOG4105DQ5	transport system permease protein
DD548_00355	ENOG4108MES	Periplasmic binding protein
DD548_00365	ENOG4105CIF	Ornithine Cyclodeaminase
DD548_00370	ENOG4105DJU	Siderophore biosynthesis protein
DD548_00375	ENOG4105C6X	Major Facilitator
DD548_00380	ENOG4105DBM	Siderophore biosynthesis protein
DD548_00385	ENOG4105DUU	IucA IucC family protein
DD548_00395	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
DD548_00400	ENOG41067FT	ParB-like nuclease domain
DD548_00430	ENOG4108IAJ	Nad-dependent epimerase dehydratase
DD548_00440	ENOG4105CPK	Glycosyl transferase (Group 1
DD548_00475	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
DD548_00480	ENOG4108J8C	transporter major facilitator family protein
DD548_00485	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
DD548_00520	ENOG4105CGH	5'-nucleotidase
DD548_00555	ENOG4108EKI	Dehydrogenase
DD548_00580	ENOG4105C5E	polysaccharide biosynthesis protein
DD548_00590	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
DD548_00620	ENOG4105D3Q	Sugar transferase
DD548_00635	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
DD548_00645	ENOG4105WD1	Membrane
DD548_00655	ENOG4105PGM	cation diffusion facilitator family transporter
DD548_00685	ENOG4105C1G	acyl-Coa dehydrogenase
DD548_00690	ENOG4108ZSU	Uncharacterized conserved protein (DUF2294)
DD548_00725	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
DD548_00735	ENOG4105C8Y	Acetylornithine aminotransferase
DD548_00740	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
DD548_00745	ENOG4105D3W	isochorismatase
DD548_00750	ENOG4107RA9	decarboxylase
DD548_00780	ENOG4105QEK	Transcriptional regulator
DD548_00790	ENOG4105DZR	Type I site-specific deoxyribonuclease
DD548_00815	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
DD548_00820	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DD548_00830	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
DD548_00865	ENOG4105EG2	ABC transporter, permease
DD548_00875	ENOG4105CK5	oxidoreductase
DD548_00885	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
DD548_00890	ENOG4105CXY	transporter
DD548_00895	ENOG4107VQW	regulatoR
DD548_00900	ENOG4105C2F	Histidine kinase
DD548_00945	ENOG4105CHU	acetyl-coa acetyltransferase
DD548_00950	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
DD548_00955	ENOG4105C1G	acyl-Coa dehydrogenase
DD548_00960	ENOG4105CEY	Amp-dependent synthetase and ligase
DD548_00965	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
DD548_00975	ENOG4107RRN	ABC transporter substrate-binding protein
DD548_00980	ENOG4105K78	MarR family Transcriptional regulator
DD548_01015	ENOG4105CI1	PTS System
DD548_01020	ENOG4105DU0	nucleoside hydrolase
DD548_01040	ENOG4105K18	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
DD548_01045	ENOG4105DT3	PTS system, galactitol-specific IIc component
DD548_01050	ENOG4105CPQ	Dehydrogenase
DD548_01060	ENOG4105CPQ	Dehydrogenase
DD548_01065	ENOG4108QHG	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
DD548_01070	ENOG4105EJJ	Dehydrogenase
DD548_01075	ENOG4107RZX	Teichoic acid biosynthesis protein
DD548_01080	ENOG4107SJB	teichoic acid biosynthesis
DD548_01090	ENOG4105EJJ	Dehydrogenase
DD548_01095	ENOG4107RZX	Teichoic acid biosynthesis protein
DD548_01140	ENOG4105CI1	PTS System
DD548_01145	ENOG4105CS2	ec 3.2.1.21
DD548_01155	ENOG4105DVA	methyltransferase
DD548_01175	ENOG4105EV1	Ribose uptake protein RbsU
DD548_01210	ENOG41061JJ	Peptidase family M23
DD548_01215	ENOG4105DA5	(ABC) transporter
DD548_01245	ENOG4105VRS	hydrolase family 18
DD548_01265	ENOG4106GSS	Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host. Negative regulator of EsaC, which is a secretion substrate of the Ess pathway in many Staphylococcus strains. Not necessary for the production and secretion of EsxA or EsxB (By similarity)
DD548_01275	ENOG4105EC2	ftsk spoIIIe
DD548_01405	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
DD548_01415	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
DD548_01445	ENOG4105D9N	nucleoside
DD548_01450	ENOG4107RJ1	sodium solute
DD548_01460	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
DD548_01465	ENOG4106KNT	transcriptional regulator
DD548_01475	ENOG4105DWD	nucleoside recognition domain protein
DD548_01500	ENOG4105DEN	Luciferase family
DD548_01525	ENOG4105CMR	udp-glucose 4-epimerase
DD548_01530	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
DD548_01540	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
DD548_01545	ENOG4105CID	antiterminator
DD548_01620	ENOG4105M6F	mutator MutT protein
DD548_01635	ENOG4106QP9	(LipO)protein
DD548_01710	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
DD548_01715	ENOG4105CFC	Transporter
DD548_01745	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
DD548_01750	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
DD548_01755	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DD548_01760	ENOG4108RZA	ABC transporter
DD548_01765	ENOG4108S9F	abc transporter, atp-binding protein
DD548_01780	ENOG4105CBC	glutamate synthase
DD548_01785	ENOG4105PQ4	(LipO)protein
DD548_01805	ENOG4105CN9	Peptidase m42 family protein
DD548_01810	ENOG41083J0	(ABC) transporter
DD548_01815	ENOG4105C4B	ABC transporter, permease
DD548_01820	ENOG4105F27	Major Facilitator
DD548_01825	ENOG4105EBR	Carboxylesterase
DD548_01830	ENOG4107QTZ	amino acid
DD548_01840	ENOG4105CZ9	Domain of unknown function (DU1801)
DD548_01860	ENOG4105E90	ABC transporter
DD548_01870	ENOG4105R40	Glycine betaine carnitine choline
DD548_01875	ENOG4105C57	major facilitator superfamily
DD548_01880	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
DD548_01895	ENOG4105ED2	Beta-lactamase
DD548_01905	ENOG4105C0X	amino acid
DD548_01915	ENOG4105EEQ	Na H antiporter
DD548_01920	ENOG4105C85	amino acid
DD548_01940	ENOG4105C2C	drug resistance transporter, Bcr CflA
DD548_01975	ENOG4105BZ1	(ABC) transporter
DD548_01990	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
DD548_01995	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
DD548_02005	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
DD548_02020	ENOG4106XHW	Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity)
DD548_02080	ENOG4105EAB	amino acid AbC transporter
DD548_02085	ENOG4105DRP	amino acid AbC transporter
DD548_02090	ENOG4105CDA	abc transporter atp-binding protein
DD548_02130	ENOG4105DSE	periplasmic solute binding protein
DD548_02145	ENOG4105TMB	Formate nitrite transporter
DD548_02150	ENOG4108XSB	acetyltransferase, (GNAT) family
DD548_02160	ENOG4108IFG	nitrite reductase, (NAD(P)H)
DD548_02165	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
DD548_02170	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
DD548_02180	ENOG4108IUE	nitrate reductase beta subunit
DD548_02210	ENOG4107TXC	Transcriptional regulator
DD548_02250	ENOG410606W	general stress protein
DD548_02280	ENOG4105ECB	domain protein
DD548_02305	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
DD548_02335	ENOG4105DWT	malate dehydrogenase (quinone)
DD548_02380	ENOG41062A4	Transcriptional regulator
DD548_02410	ENOG4105CW7	secretion protein, HlyD family
DD548_02415	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
DD548_02440	ENOG4105D7N	magnesium and cobalt transport protein CorA
DD548_02450	ENOG4105D6U	Sodium Glutamate Symporter
DD548_02465	ENOG4105KAF	membrAne
DD548_02470	ENOG4108IUX	(ABC) transporter
DD548_02475	ENOG4105RHA	ABC transporter, permease
DD548_02495	ENOG4108RPX	mosc domain containing protein
DD548_02500	ENOG4105E66	phosphoriboisomerase A
DD548_02520	ENOG4105C5Q	Transcriptional regulator
DD548_02525	ENOG4105CGP	Urocanate hydratase
DD548_02535	ENOG4105CH2	amidohydrolase
DD548_02540	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
DD548_02560	ENOG4108Q3X	Transcriptional regulator
DD548_02565	ENOG4105CI1	PTS System
DD548_02575	ENOG4105C09	Bile acid
DD548_02580	ENOG4107YBY	Hydrolase
DD548_02655	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
DD548_02690	ENOG4105DFD	Na H antiporter
DD548_02700	ENOG41068JE	domain protein
DD548_02770	ENOG4105FDT	acyl-CoA dehydrogenase
DD548_02790	ENOG4107ZYJ	bioY protein
DD548_02805	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
DD548_02810	ENOG4105E0C	molybdate abc transporter
DD548_02815	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
DD548_02820	ENOG4105D06	uba thif-type nad fad binding protein
DD548_02825	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
DD548_02835	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
DD548_02840	ENOG4108129	molybdopterin-guanine dinucleotide biosynthesis protein
DD548_02845	ENOG4108ZAF	Molybdopterin
DD548_02930	ENOG4105CSC	Glucose uptake protein
DD548_02950	ENOG4105C7N	Xanthine uracil vitamin C permease
DD548_03065	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
DD548_03070	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
DD548_03150	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
DD548_03175	ENOG4107FQX	Alpha-acetolactate decarboxylase
DD548_03195	ENOG4106AM8	polysaccharide lyase family 8
DD548_03205	ENOG4105VUF	Transcriptional regulator
DD548_03230	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
DD548_03235	ENOG4105E98	transcriptional regulator DeoR family
DD548_03260	ENOG4105VCP	PTS System
DD548_03265	ENOG4105CK1	PTS System
DD548_03280	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
DD548_03285	ENOG4105CIS	alcohol dehydrogenase
DD548_03290	ENOG4105C94	Transporter
DD548_03320	ENOG4107SFI	Major Facilitator superfamily
DD548_03330	ENOG4106M28	alanine racemase domain protein
DD548_03340	ENOG4108HUF	Transporter
DD548_03345	ENOG4105DQ5	transport system permease protein
DD548_03350	ENOG4108U1V	ABC transporter, permease
DD548_03355	ENOG4105DWD	nucleoside recognition domain protein
DD548_03365	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
DD548_03375	ENOG4108UT2	hemolysin iii
DD548_03395	ENOG4105D1F	ATP-binding protein
DD548_03465	ENOG4105CYW	agmatinase
DD548_03470	ENOG4105C8B	TIGR00159 family
DD548_03490	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
DD548_03495	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
DD548_03500	ENOG4105ETD	TRANSCRIPTIONal
DD548_03505	ENOG4105CTS	PTS system mannitol-specific
DD548_03510	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
DD548_03515	ENOG4105DKW	ABC transporter
DD548_03555	ENOG4105PGM	cation diffusion facilitator family transporter
DD548_03570	ENOG4105DG6	mannose-6-phosphate isomerase
DD548_03590	ENOG4108RMU	ferritin dps family protein
DD548_03595	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
DD548_03600	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
DD548_03655	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
DD548_03665	ENOG4105D2N	Aldolase
DD548_03685	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
DD548_03710	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
DD548_03715	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DD548_03740	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
DD548_03800	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
DD548_03830	ENOG4105DWF	phosphomethylpyrimidine kinase
DD548_03870	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
DD548_03875	ENOG4105VPX	protein, conserved in bacteria
DD548_03900	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
DD548_03910	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
DD548_03915	ENOG4105C08	Histidine kinase
DD548_03930	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
DD548_03935	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
DD548_03945	ENOG4105CKV	Membrane
DD548_03960	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
DD548_03980	ENOG4107SGM	protein serine threonine phosphatase
DD548_03985	ENOG4105WN5	stage II sporulation protein
DD548_04055	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
DD548_04075	ENOG4105C7K	acetolactate synthase
DD548_04090	ENOG4105K8N	protein family UPF0079, ATPase
DD548_04095	ENOG41072GX	Peptidase M22 Glycoprotease
DD548_04100	ENOG410801F	ribosomal-protein-alanine acetyltransferase
DD548_04110	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
DD548_04120	ENOG4105C5H	ABC transporter
DD548_04130	ENOG4105CUC	YeeE YedE family protein
DD548_04140	ENOG4105BZU	Histidine kinase
DD548_04165	ENOG4108WCX	response regulator
DD548_04190	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
DD548_04220	ENOG4105VTR	Integrase
DD548_04305	ENOG4108TFU	terminase (Small subunit)
DD548_04335	ENOG4105CZN	Potassium uptake protein
DD548_04395	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
DD548_04470	ENOG4106CVF	DNA replication protein
DD548_04585	ENOG4105EFC	phage portal protein HK97 family
DD548_04640	ENOG4105DR5	peptidase
DD548_04685	ENOG4105ZMJ	n-acetylmuramoyl-l-alanine amidase
DD548_04690	ENOG4106Z3D	Potent plasminogen activator that converts plasminogen into plasmin. It forms a 1 1 complex with plasmin, which in turn activates other plasminogen molecules
DD548_04705	ENOG4105ZMJ	n-acetylmuramoyl-l-alanine amidase
DD548_04730	ENOG4108QYW	Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity)
DD548_04755	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
DD548_04770	ENOG4105CJ1	ABC, transporter
DD548_04820	ENOG4108FPN	Integrase
DD548_04825	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DD548_04865	ENOG4105C26	Dehydrogenase
DD548_04890	ENOG4105C8P	)-transporter
DD548_04900	ENOG4105CQC	Prephenate dehydratase
DD548_04905	ENOG4107QN4	Catalyzes the production of nitric oxide (By similarity)
DD548_04910	ENOG4105DAP	Nicotinate phosphoribosyltransferase
DD548_04935	ENOG4107DDB	Cysteine protease able to
DD548_04950	ENOG4105KGF	protein, YerC YecD
DD548_04955	ENOG4108RTE	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity)
DD548_04960	ENOG4105C4R	Atp-dependent dna helicase
DD548_05010	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
DD548_05020	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
DD548_05095	ENOG4105ENE	Histidine kinase
DD548_05100	ENOG4105WH1	Two component transcriptional regulator luxr family
DD548_05105	ENOG4107U9T	Pfam:Ribonuclease_BN
DD548_05130	ENOG4108S4H	thioesterase Superfamily protein
DD548_05140	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DD548_05225	ENOG4106CVF	DNA replication protein
DD548_05275	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
DD548_05420	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
DD548_05440	ENOG4105ZMJ	n-acetylmuramoyl-l-alanine amidase
DD548_05480	ENOG4105EY8	ABC transporter
DD548_05495	ENOG41067AE	Membrane-bound metal-dependent hydrolase
DD548_05520	ENOG4107NBY	Membrane
DD548_05530	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DD548_05535	ENOG4108M3J	Dehydrogenase
DD548_05710	ENOG4105E5Q	amino acid AbC transporter
DD548_05715	ENOG4105CDA	abc transporter atp-binding protein
DD548_05720	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
DD548_05755	ENOG4105C9Q	fumarate hydratase class II
DD548_05760	ENOG4108YBP	pseudouridine synthase
DD548_05765	ENOG4105BZU	Histidine kinase
DD548_05770	ENOG4105WH1	Two component transcriptional regulator luxr family
DD548_05800	ENOG4107VRP	DNA repair exonuclease
DD548_05835	ENOG4105K59	histidine triad (HIT) protein
DD548_05870	ENOG4105C1Q	protoporphyrinogen oxidase
DD548_05990	ENOG4105DA5	(ABC) transporter
DD548_06045	ENOG4108CHM	Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases
DD548_06180	ENOG4108RS6	transposase
DD548_06200	ENOG4105CV8	reductase
DD548_06210	ENOG4106A8V	Protein CrcB homolog
DD548_06215	ENOG4106A8V	Protein CrcB homolog
DD548_06225	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
DD548_06245	ENOG4106FBB	RNA Polymerase
DD548_06255	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
DD548_06265	ENOG4107R3E	Citrate transporter
DD548_06280	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
DD548_06285	ENOG4108R6K	riboflavin synthase, subunit alpha
DD548_06290	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
DD548_06315	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
DD548_06335	ENOG4105N5T	Radical SAM Protein
DD548_06340	ENOG410605W	Major Facilitator
DD548_06360	ENOG4105CBX	hi0933 family
DD548_06390	ENOG4105F0I	Aminotransferase
DD548_06395	ENOG4108V15	phosphotransferase enzyme family
DD548_06405	ENOG4105C8F	Beta-lactamase domain protein
DD548_06430	ENOG4108VDD	TRNA binding domain protein
DD548_06460	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
DD548_06470	ENOG4105ETE	Transcriptional regulator (LacI family
DD548_06475	ENOG4105DGU	Histone deacetylase
DD548_06480	ENOG4105F1V	Acetoin utilization protein
DD548_06490	ENOG4105CKU	formyltetrahydrofolate synthetase
DD548_06520	ENOG4105C0H	protease
DD548_06525	ENOG4105F6E	Acyl-transferase
DD548_06545	ENOG4108JQ1	Dehydrogenase
DD548_06550	ENOG4105C5R	Aminotransferase
DD548_06555	ENOG4108X3M	OsmC Ohr family protein
DD548_06560	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
DD548_06610	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
DD548_06665	ENOG4105SFS	phosphoesterase RecJ domain protein
DD548_06670	ENOG4105C0B	DNA polymerase III (alpha subunit)
DD548_06675	ENOG4105C6K	Malic enzyme
DD548_06705	ENOG4105C85	amino acid
DD548_06710	ENOG4105BZN	citrate synthase
DD548_06715	ENOG4108HMX	isocitrate dehydrogenase (NADP)
DD548_06725	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
DD548_06730	ENOG4105BZU	Histidine kinase
DD548_06740	ENOG4105C2M	dna polymerase I
DD548_06745	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
DD548_06755	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
DD548_06780	ENOG4105C22	threonyL-tRNA synthetase
DD548_06785	ENOG4108IQI	permease
DD548_06810	ENOG4105U6W	MutT NUDIX family protein
DD548_06840	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
DD548_06860	ENOG4105D52	delta-aminolevulinic acid dehydratase
DD548_06880	ENOG4108R3E	Dna-3-methyladenine glycosylase i
DD548_06890	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
DD548_06900	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
DD548_06945	ENOG4105X36	(ribosomal) protein
DD548_06985	ENOG4105VIE	preprotein translocase, subunit YajC
DD548_06990	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
DD548_06995	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
DD548_07025	ENOG4105C9M	aspartyl-trna synthetase
DD548_07040	ENOG4105CUZ	uba thif-type nad fad binding protein
DD548_07045	ENOG4105D1H	recombination factor protein RarA
DD548_07065	ENOG4105DEN	Luciferase family
DD548_07070	ENOG4105C3J	Cysteine desulfurase
DD548_07085	ENOG4105C7H	Helicase, RecD TraA family
DD548_07115	ENOG4105XYU	peptidase (U32 family)
DD548_07120	ENOG4105CFP	Peptidase U32
DD548_07145	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
DD548_07160	ENOG4105C5A	transporter
DD548_07185	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
DD548_07190	ENOG4105CQW	ribosome biogenesis GTPase YqeH
DD548_07200	ENOG410812S	Rna-binding protein
DD548_07210	ENOG4108WF2	Metal Dependent Phosphohydrolase
DD548_07215	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
DD548_07220	ENOG4105DXX	methyltransferase
DD548_07230	ENOG4108UK2	deaminase
DD548_07235	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
DD548_07240	ENOG4105TQK	DNA polymerase iii, delta' subunit
DD548_07260	ENOG4105CSA	Coproporphyrinogen iii oxidase
DD548_07290	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
DD548_07295	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
DD548_07305	ENOG4105F7J	membrane-bound serine protease
DD548_07320	ENOG4105C9A	Phoh family
DD548_07335	ENOG4105KG3	cytidine deaminase
DD548_07340	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
DD548_07365	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
DD548_07370	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DD548_07380	ENOG4105EGD	dinuclear metal center protein, YbgI family
DD548_07385	ENOG4105C1J	atp-dependent rna helicase
DD548_07395	ENOG4105FDK	ABC transporter
DD548_07400	ENOG4105FAV	ABC, transporter
DD548_07405	ENOG4105N80	Ferric uptake regulator, Fur family
DD548_07415	ENOG4107RF6	penicillin-binding protein
DD548_07425	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
DD548_07450	ENOG4105C5X	domain protein
DD548_07460	ENOG4105D7Q	type ii secretion system
DD548_07465	ENOG4106855	Competence protein
DD548_07490	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
DD548_07510	ENOG4105WZW	rhodanese family
DD548_07515	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
DD548_07530	ENOG4105DC7	peptidase M24
DD548_07545	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
DD548_07550	ENOG4108ZSR	alkaline shock protein
DD548_07580	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
DD548_07595	ENOG4105CPP	Dehydrogenase, E1 component
DD548_07600	ENOG4105C7S	Dehydrogenase
DD548_07610	ENOG4108QEG	Membrane
DD548_07620	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
DD548_07625	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
DD548_07655	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
DD548_07665	ENOG4105II7	pyrroline-5-carboxylate reductase
DD548_07670	ENOG4105PDP	Short chain dehydrogenase
DD548_07680	ENOG4105CPC	Aldo Keto reductase
DD548_07685	ENOG4108YZ4	nudix hydrolase
DD548_07690	ENOG4105I3K	Ferric uptake regulator, Fur family
DD548_07695	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DD548_07715	ENOG4105FE9	pseudouridine synthase
DD548_07720	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DD548_07725	ENOG4105BZU	Histidine kinase
DD548_07780	ENOG4105C9U	ATP-dependent DNA helicase RecQ
DD548_07795	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
DD548_07800	ENOG4105HDK	L-asparaginase
DD548_07825	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
DD548_07840	ENOG4105K70	DNA-binding protein
DD548_07860	ENOG4105EAH	synthase
DD548_07880	ENOG4105D49	3-dehydroquinate synthase
DD548_07895	ENOG4105QKB	UPF0302 protein
DD548_07910	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
DD548_07915	ENOG4105CPK	Glycosyl transferase (Group 1
DD548_07920	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DD548_07945	ENOG4105CSM	endonuclease III
DD548_07955	ENOG4105BZ4	penicillin-binding protein
DD548_07995	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
DD548_08010	ENOG410890F	Dynamin family
DD548_08020	ENOG4105DCF	alanine dehydrogenase
DD548_08030	ENOG4107R7I	amino acid
DD548_08070	ENOG4106QQ5	PBS lyase HEAT domain protein repeat-containing protein
DD548_08085	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
DD548_08095	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
DD548_08105	ENOG4105C5Y	PTS System
DD548_08115	ENOG4105CN1	protease
DD548_08125	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
DD548_08130	ENOG410841Q	phosphoesterase PA-phosphatase related protein
DD548_08180	ENOG4107T89	von Willebrand factor, type A
DD548_08230	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
DD548_08235	ENOG4108XFP	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
DD548_08260	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
DD548_08265	ENOG4105CFH	Aspartokinase
DD548_08270	ENOG4105C5H	ABC transporter
DD548_08290	ENOG4105C8U	phosphate abc transporter
DD548_08295	ENOG4105E2Z	phosphate ABC transporter (Permease
DD548_08305	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
DD548_08310	ENOG4105DPN	Oligoendopeptidase f
DD548_08350	ENOG4108KP7	hydrolase
DD548_08360	ENOG4108TV1	Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity)
DD548_08365	ENOG4108RMH	femAB family
DD548_08395	ENOG4105DDQ	anthranilate synthase
DD548_08400	ENOG4105CRQ	synthase (Component I)
DD548_08405	ENOG4105DER	m42 family
DD548_08415	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
DD548_08425	ENOG4108RCF	TRANSCRIPTIONal
DD548_08430	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
DD548_08435	ENOG4105FF5	Membrane
DD548_08465	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DD548_08470	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DD548_08500	ENOG4108I0Z	Aconitate hydratase
DD548_08510	ENOG4105C94	Transporter
DD548_08520	ENOG4105EYH	Exonuclease
DD548_08545	ENOG4105CV1	Transketolase (EC 2.2.1.1)
DD548_08565	ENOG4105K4I	Scp-like extracellular
DD548_08595	ENOG4108IQI	permease
DD548_08620	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
DD548_08625	ENOG4105D6E	homoserine dehydrogenase
DD548_08630	ENOG4105CFH	Aspartokinase
DD548_08655	ENOG4108S01	response regulator
DD548_08670	ENOG4108M15	ABC transporter
DD548_08675	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
DD548_08785	ENOG4105C5F	glutamine synthetase
DD548_08790	ENOG4105KV4	Transcriptional regulator
DD548_08795	ENOG4105CXI	aluminum resistance protein
DD548_08800	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
DD548_08805	ENOG4108V06	Glutathione peroxidase
DD548_08810	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
DD548_08835	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
DD548_08840	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
DD548_08850	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
DD548_08875	ENOG4105DQU	oxidoreductase, subunit beta
DD548_08880	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
DD548_08885	ENOG4105D48	metallophosphoesterase
DD548_08905	ENOG4105CEV	competence damage-inducible protein
DD548_08910	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
DD548_08925	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
DD548_08940	ENOG4105FDP	GntR family transcriptional regulator
DD548_08945	ENOG4105CNU	cell division protein FtsK
DD548_08970	ENOG4105DTN	riboflavin biosynthesis protein ribF
DD548_08995	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
DD548_09000	ENOG4105CHV	Transcription elongation factor NusA
DD548_09025	ENOG4105DZP	Membrane-associated zinc metalloprotease
DD548_09030	ENOG4105KNE	Phosphatidate cytidylyltransferase
DD548_09035	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
DD548_09100	ENOG4105C79	DNA protecting protein DprA
DD548_09110	ENOG41068KG	domain protein
DD548_09115	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
DD548_09130	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
DD548_09170	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DD548_09175	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
DD548_09195	ENOG4105CHR	reductase
DD548_09200	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
DD548_09215	ENOG4105CB5	ATP-dependent DNA helicase recG
DD548_09225	ENOG4108ZAA	Alkaline-shock protein
DD548_09240	ENOG4105DJV	ribulose-phosphate 3-epimerase
DD548_09245	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
DD548_09255	ENOG4108ZF3	Phosphatase
DD548_09265	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
DD548_09275	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
DD548_09280	ENOG4105YB8	TM2 domain containing protein
DD548_09290	ENOG4105C25	Primosomal protein n'
DD548_09295	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
DD548_09310	ENOG4105F23	Fibronectin-binding protein
DD548_09325	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
DD548_09340	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
DD548_09345	ENOG4105CD3	dihydroorotase
DD548_09365	ENOG4105C34	Pseudouridine synthase
DD548_09385	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
DD548_09400	ENOG4105DBK	s4 domain protein
DD548_09405	ENOG41067XK	integral membrane protein
DD548_09415	ENOG4105DFA	alanine racemase domain protein
DD548_09420	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
DD548_09425	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
DD548_09430	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
DD548_09435	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
DD548_09450	ENOG4105CJN	penicillin-binding protein
DD548_09455	ENOG41068DC	Essential cell division protein (By similarity)
DD548_09515	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
DD548_09525	ENOG4105DBV	ornithine carbamoyltransferase
DD548_09555	ENOG4106UK0	Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity
DD548_09620	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
DD548_09630	ENOG4105E33	succinate dehydrogenase
DD548_09640	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
DD548_09665	ENOG4105DCG	PHP domain protein
DD548_09690	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
DD548_09700	ENOG4108RWN	rrna methyltransferase
DD548_09715	ENOG4105KFN	sortase, SrtB family
DD548_09775	ENOG4106H78	methyltransferase
DD548_09825	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
DD548_09830	ENOG4105CNI	cell division protein FtsW
DD548_09850	ENOG4105CI3	gtp-binding protein typa
DD548_09860	ENOG4105ECY	inositol monophosphatase
DD548_09885	ENOG4107RUE	extracellular solute-binding protein family 1
DD548_09890	ENOG4105D38	putrescine abc transporter
DD548_09895	ENOG4105F38	ABC transporter, permease
DD548_09915	ENOG4107QN2	dihydrolipoyl dehydrogenase
DD548_09920	ENOG4105C7S	Dehydrogenase
DD548_09925	ENOG4105CPP	Dehydrogenase, E1 component
DD548_09930	ENOG4107RUY	(E1 component), alpha subunit
DD548_09940	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
DD548_09960	ENOG4107ZYR	domain protein
DD548_09980	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
DD548_09985	ENOG4105KRI	phosphocarrier protein (HPr
DD548_09995	ENOG4105DR4	Methyltransferase
DD548_10020	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
DD548_10025	ENOG4108JJB	ABC transporter
DD548_10030	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
DD548_10035	ENOG4105C12	Phosphoribosylglycinamide synthetase
DD548_10040	ENOG4105DC1	bifunctional purine biosynthesis protein purh
DD548_10045	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
DD548_10055	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
DD548_10070	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
DD548_10080	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
DD548_10085	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
DD548_10125	ENOG4105FQP	Beta-lactamase
DD548_10130	ENOG4108KGH	TRANSCRIPTIONal
DD548_10140	ENOG41082BV	acetyltransferase
DD548_10145	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
DD548_10160	ENOG4108TGC	Acyltransferase
DD548_10165	ENOG4105CHM	Aminotransferase
DD548_10170	ENOG4108CHM	Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases
DD548_10185	ENOG4108IPT	Naphthoate synthase
DD548_10190	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
DD548_10200	ENOG4105E4F	Isochorismate synthase
DD548_10210	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
DD548_10215	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
DD548_10220	ENOG4105YB8	TM2 domain containing protein
DD548_10230	ENOG4108HUF	Transporter
DD548_10255	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
DD548_10305	ENOG4105XVF	Competence transcription factor
DD548_10320	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
DD548_10330	ENOG4105C0H	protease
DD548_10335	ENOG4107TS3	membrane protein, TerC
DD548_10375	ENOG4105BZG	amino acid carrier protein
DD548_10380	ENOG4105C02	permease
DD548_10395	ENOG4105CJW	magnesium transporter
DD548_10400	ENOG4105EMS	pseudouridine synthase
DD548_10415	ENOG4106EFP	UPF0738 protein
DD548_10425	ENOG4108Z18	K06886 hemoglobin
DD548_10430	ENOG4105T58	Dithiol-disulfide isomerase
DD548_10435	ENOG4105DPN	Oligoendopeptidase f
DD548_10450	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
DD548_10455	ENOG4105C31	Tryptophanyl-tRNA synthetase
DD548_10460	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DD548_10470	ENOG4108JQ7	(ABC) transporter
DD548_10480	ENOG4105DEF	Extracellular solute-binding protein, family 5
DD548_10490	ENOG4108JQ7	(ABC) transporter
DD548_10500	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DD548_10505	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
DD548_10515	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
DD548_10535	ENOG4105KIS	phospholipid-binding protein
DD548_10550	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
DD548_10560	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
DD548_10565	ENOG4105EXC	Acyl-transferase
DD548_10575	ENOG4108KP7	hydrolase
DD548_10595	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
DD548_10605	ENOG4105C3F	Signal peptidase i
DD548_10620	ENOG4107QYV	phosphohexose isomerase
DD548_10635	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
DD548_10645	ENOG4105D82	Glutamate dehydrogenase
DD548_10650	ENOG4105C8Y	Acetylornithine aminotransferase
DD548_10655	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
DD548_10660	ENOG41060GV	RNA binding s1 domain protein
DD548_10715	ENOG4105KA0	thioesterase Superfamily protein
DD548_10725	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
DD548_10735	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
DD548_10755	ENOG41083MR	nifu domain-containing protein
DD548_10760	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
DD548_10770	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
DD548_10810	ENOG4105MMD	transcriptional regulator
DD548_10830	ENOG4105I3N	Conserved Protein
DD548_10870	ENOG4108UNV	SUF system FeS assembly protein, NifU family
DD548_10875	ENOG4105C9B	Cysteine desulfurase
DD548_10880	ENOG4105JRK	feS assembly protein SufD
DD548_10885	ENOG4105C3K	feS assembly ATPase SufC
DD548_10900	ENOG4105D01	(LipO)protein
DD548_10905	ENOG4108UMI	ABC transporter, permease
DD548_10930	ENOG4108XI2	Domain of unknown function (DUF1963)
DD548_10945	ENOG41080E8	Transcriptional regulator, Spx MgsR family
DD548_10950	ENOG4105SZ6	Thioredoxin
DD548_10975	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
DD548_10980	ENOG4105CVJ	phosphoglycerate mutase
DD548_11020	ENOG4105VEQ	Cold shock protein
DD548_11025	ENOG4107Y9E	nuclease
DD548_11045	ENOG4106HV3	Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps
DD548_11095	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
DD548_11105	ENOG4105XZU	Preprotein translocase, subunit SecG
DD548_11120	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
DD548_11135	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
DD548_11170	ENOG4105CHW	UPF0052 protein
DD548_11185	ENOG4105C3M	thioredoxin reductase
DD548_11195	ENOG4108S4C	acetyltransferase
DD548_11210	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
DD548_11215	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
DD548_11230	ENOG41068JE	domain protein
DD548_11260	ENOG41081UC	Inherit from COG: Competence protein
DD548_11275	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
DD548_11280	ENOG4105ESV	Glycosyl transferase, family 4
DD548_11340	ENOG4108IPW	abc transporter atp-binding protein
DD548_11345	ENOG4105CM4	permease protein
DD548_11350	ENOG4105DHS	permease protein
DD548_11365	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
DD548_11370	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
DD548_11400	ENOG4105DUX	Transporter
DD548_11420	ENOG4108ZIE	5 nucleotidase deoxy cytosolic type C
DD548_11430	ENOG4105E90	ABC transporter
DD548_11435	ENOG4108IJ8	ABC transporter
DD548_11440	ENOG4105C9U	ATP-dependent DNA helicase RecQ
DD548_11445	ENOG4105C5H	ABC transporter
DD548_11475	ENOG4105CRQ	synthase (Component I)
DD548_11480	ENOG4105DDQ	anthranilate synthase
DD548_11490	ENOG4107ZAE	6-carboxy-5,6,7,8-tetrahydropterin synthase
DD548_11495	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
DD548_11525	ENOG4105CKK	Glycosyl transferase, family 2
DD548_11535	ENOG4105C37	(CBS) domain
DD548_11540	ENOG4105CE4	GlcNAc 6-P deacetylase
DD548_11545	ENOG4105DM4	PTS System
DD548_11550	ENOG4105DE4	1-phosphofructokinase
DD548_11555	ENOG4105E98	transcriptional regulator DeoR family
DD548_11560	ENOG4108Z66	YbaK ebsC protein
DD548_11570	ENOG4105DP8	Major facilitator superfamily MFS_1
DD548_11590	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
DD548_11595	ENOG4107QPK	)-transporter
DD548_11605	ENOG4107QM2	Aldo Keto reductase
DD548_11610	ENOG4105CKI	cobalamin synthesis protein
DD548_11615	ENOG41083AI	transcriptional regulator), MarR family
DD548_11620	ENOG4108JJ8	(ABC) transporter
DD548_11625	ENOG4108JJ9	ABC, transporter
DD548_11645	ENOG4108URH	decarboxylase
DD548_11650	ENOG4108YYQ	gCN5-related N-acetyltransferase
DD548_11675	ENOG4105SXS	Protein of unknown function (DUF456)
DD548_11680	ENOG4105S8Q	sugar efflux transporter
DD548_11715	ENOG4105ID8	Transcriptional regulator, ARAC family
DD548_11730	ENOG4105VRS	hydrolase family 18
DD548_11735	ENOG4105CJ3	phosphate transporter
DD548_11740	ENOG4107GRR	phosphate transport regulator
DD548_11750	ENOG4105C19	ABC transporter
DD548_11790	ENOG4108K88	Membrane
DD548_11800	ENOG4105VDH	Dihydroxyacetone kinase
DD548_11810	ENOG4105CMT	Dihydroxyacetone kinase
DD548_11815	ENOG4105EHG	Permease protein
DD548_11820	ENOG4105DQ5	transport system permease protein
DD548_11825	ENOG4105E0A	ABC, transporter
DD548_11830	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
DD548_11845	ENOG4105BZ1	(ABC) transporter
DD548_11855	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
DD548_11880	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
DD548_11890	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
DD548_11895	ENOG4105DIK	(ABC) transporter
DD548_11900	ENOG4105CC5	ABC transporter
DD548_11905	ENOG4105DSE	periplasmic solute binding protein
DD548_11910	ENOG4105EEQ	Na H antiporter
DD548_11950	ENOG4105E71	FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off
DD548_11990	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
DD548_12000	ENOG4108IU2	vtamin B12-transporter permease
DD548_12005	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
DD548_12040	ENOG4108XFG	YwhD family
DD548_12045	ENOG4105DCI	Phosphohydrolase
DD548_12055	ENOG4108WS4	fmn reductase
DD548_12060	ENOG4105CPC	Aldo Keto reductase
DD548_12150	ENOG4107QN2	dihydrolipoyl dehydrogenase
DD548_12170	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
DD548_12175	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
DD548_12180	ENOG4108IJ2	phosphate acetyltransferase
DD548_12225	ENOG4105DWF	phosphomethylpyrimidine kinase
DD548_12275	ENOG4108VA3	3-hexulose-6-phosphate synthase
DD548_12290	ENOG4107YEI	lmbE family
DD548_12310	ENOG4105DUY	Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein
DD548_12320	ENOG4105DUY	Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein
DD548_12335	ENOG410667J	hydrolase
DD548_12340	ENOG4108Z6B	deaminase
DD548_12350	ENOG4105ZMH	deoxynucleoside kinase
DD548_12355	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
DD548_12365	ENOG4105CM2	brancheD-chain amino acid aminotransferase
DD548_12385	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
DD548_12420	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DD548_12430	ENOG4107Y49	methyltransferase
DD548_12460	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
DD548_12465	ENOG410683Z	Preprotein translocase SecE subunit
DD548_12485	ENOG4105C2N	RNA methyltransferase TrmH family group 3
DD548_12490	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DD548_12515	ENOG4105CTP	PilT protein domain protein
DD548_12520	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
DD548_12535	ENOG4108Z0C	Uvrb UvrC protein
DD548_12545	ENOG4105D9N	nucleoside
DD548_12560	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
DD548_12655	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DD548_12660	ENOG4105KRF	dihydroneopterin aldolase
DD548_12670	ENOG4105C6T	cysteine synthase
DD548_12680	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DD548_12685	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
DD548_12690	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
DD548_12695	ENOG41060GV	RNA binding s1 domain protein
DD548_12705	ENOG41082I2	s4 domain protein
DD548_12710	ENOG4108IY2	MazG family
DD548_12740	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
DD548_12760	ENOG4105KME	endoribonuclease L-psp
DD548_12765	ENOG4105DFT	pur operon repressor
DD548_12775	ENOG4105W42	Veg protein
DD548_12785	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
DD548_12790	ENOG4105F8V	Hydrolase, tatD family
DD548_12795	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
DD548_12800	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
DD548_12810	ENOG41060K3	Methyltransferase
DD548_12820	ENOG4105MA4	psp1 domain protein
DD548_12825	ENOG4105FA2	dna polymerase iii
DD548_12830	ENOG4105X0R	protein from nitrogen regulatory protein P-II
DD548_12840	ENOG4105CXN	decarboxylase
DD548_12870	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
DD548_12875	ENOG4105C6E	dna polymerase iii
DD548_12895	ENOG4107414	GntR family transcriptional regulator
DD548_12900	ENOG4105CG3	alpha amylase, catalytic region
DD548_12905	ENOG4105C5Y	PTS System
DD548_12915	ENOG4105BZ8	glutamate synthase
DD548_12920	ENOG4105CBC	glutamate synthase
DD548_12925	ENOG4105C5Q	Transcriptional regulator
DD548_12960	ENOG4105D01	(LipO)protein
DD548_12965	ENOG4108UMI	ABC transporter, permease
DD548_12975	ENOG4105C28	cystathionine
DD548_12985	ENOG4105C8J	)-transporter
DD548_13010	ENOG4105GPN	Uncharacterized conserved protein (DUF2294)
DD548_13015	ENOG4105EVH	UPF0753 protein
DD548_13020	ENOG4108TWJ	NADH dehydrogenase subunit 5
DD548_13045	ENOG4105CKI	cobalamin synthesis protein
DD548_13205	ENOG4105KA3	membrAne
DD548_13245	ENOG4105C2W	permease
DD548_13280	ENOG4107R6U	sodium dicarboxylate symporter
DD548_13295	ENOG4108JU3	Alkyl hydroperoxide reductase
DD548_13355	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DD548_13370	ENOG4108UUM	single-stranded DNA-binding protein
DD548_13390	ENOG4105C3G	gtp-binding protein
DD548_13395	ENOG4105VDK	protein, conserved in bacteria
DD548_13400	ENOG4105D8X	mechanosensitive ion channel
DD548_13405	ENOG4105FA0	parb-like partition protein
DD548_13415	ENOG4105C28	cystathionine
DD548_13420	ENOG4105C28	cystathionine
DD548_13455	ENOG4105DA5	(ABC) transporter
DD548_13465	ENOG4105VZ8	Transcriptional regulator
DD548_13475	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
DD548_13480	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
DD548_13485	ENOG4107SJW	iron permease, FTR1
DD548_13490	ENOG4105DBE	peroxidase
DD548_13495	ENOG410650H	(LipO)protein
DD548_13510	ENOG4105HMI	Membrane
DD548_13515	ENOG4107V0Z	fmn reductase
DD548_13530	ENOG4105CXY	transporter
DD548_13580	ENOG4106PHI	plasmid recombination enzyme
DD548_13585	ENOG4106PHI	plasmid recombination enzyme
DD548_13590	ENOG4106PHI	plasmid recombination enzyme
DD548_13595	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
DD548_13645	ENOG4105ZX1	Transposase C
DD548_13715	ENOG41078HS	Fibronectin binding protein B
DD548_13735	ENOG4105CMG	Carbohydrate kinase
DD548_13740	ENOG4105G3Z	GntR family transcriptional regulator
DD548_13755	ENOG4105NRR	Uncharacterized protein conserved in bacteria (DUF2188)
DD548_13765	ENOG4105DJB	Major Facilitator Superfamily
DD548_13770	ENOG4107T5V	SNARE associated Golgi
DD548_13800	ENOG4105CJ1	ABC, transporter
DD548_13820	ENOG4105FBA	Phospholipase Carboxylesterase
DD548_13830	ENOG41090MY	MarR family Transcriptional regulator
DD548_13840	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
DD548_13850	ENOG4105C5I	Dehydrogenase
DD548_13855	ENOG4108AZI	Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity)
DD548_13860	ENOG4108Z15	abc transporter atp-binding protein
DD548_13865	ENOG4106KKU	
DD548_13870	ENOG4108Z6X	(sortase) family
DD548_13875	ENOG4108Z7F	N-acetyltransferase
DD548_13890	ENOG4105EJQ	L-serine dehydratase
DD548_13910	ENOG4108UZ3	Transporter
DD548_13945	ENOG41067MG	lrgb family
DD548_13955	ENOG4105CMU	LysR family (Transcriptional regulator
DD548_13965	ENOG41068JE	domain protein
DD548_13990	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
DD548_13995	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
DD548_14010	ENOG4105CE1	Ferrous iron transport protein b
DD548_14020	ENOG4105EYF	MMPL domain protein
DD548_14040	ENOG4108UW5	maltose o-acetyltransferase
DD548_14050	ENOG4105C59	p-type ATPase
DD548_14095	ENOG41068JE	domain protein
DD548_14100	ENOG4105EXC	Acyl-transferase
DD548_14160	ENOG4105CHR	reductase
DD548_14170	ENOG4108SXP	alpha beta
DD548_14185	ENOG4107T5J	pyridine nucleotide-disulfide oxidoreductase
DD548_14210	ENOG4105FGM	Fructosamine kinase
DD548_14215	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
DD548_14255	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
DD548_14265	ENOG4108NKJ	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
DD548_14270	ENOG4107FQX	Alpha-acetolactate decarboxylase
DD548_14285	ENOG4105CUB	amino acid
DD548_14290	ENOG4108JPW	Aminotransferase
DD548_14305	ENOG4105DWT	malate dehydrogenase (quinone)
DD548_14315	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DD548_14335	ENOG4105C26	Dehydrogenase
DD548_14345	ENOG4105TRT	Transcriptional regulator
DD548_14355	ENOG4105C94	Transporter
DD548_14370	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
DD548_14375	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
DD548_14380	ENOG4105D4T	Citrate transporter
DD548_14390	ENOG4108Z73	Siroheme synthase
DD548_14395	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
DD548_14450	ENOG4105G6Z	alkaline phosphatase
DD548_14460	ENOG4108U05	Transcriptional regulator
DD548_14470	ENOG4105T6C	Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps
DD548_14490	ENOG4105DBV	ornithine carbamoyltransferase
DD548_14495	ENOG4105CEU	Arginine dihydrolase
DD548_14530	ENOG4105DM4	PTS System
DD548_14535	ENOG4105DG6	mannose-6-phosphate isomerase
DD548_14545	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
DD548_14550	ENOG4105WQI	isochorismatase
DD548_14575	ENOG4106E62	Accessory Sec system protein Asp3
DD548_14580	ENOG41089G2	accessory Sec system protein Asp2
DD548_14585	ENOG4108XJK	accessory Sec system protein Asp1
DD548_14590	ENOG4106YAG	Part of the accessory SecA2 SecY2 system specifically required for export of
DD548_14600	ENOG4105EW6	flavin reductase domain protein, FMN-binding
DD548_14620	ENOG4107XC4	flavin reductase domain protein, FMN-binding
DD548_14625	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
DD548_14645	ENOG4105HTX	biosynthesis protein
DD548_14650	ENOG4108IG5	Transcriptional regulator
DD548_14655	ENOG4107QJZ	Glycosyl transferase, family 2
DD548_14665	ENOG4107UVV	polysaccharide deacetylase
DD548_14675	ENOG4105J1V	Triacylglycerol lipase
DD548_14685	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
DD548_14700	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
DD548_14710	ENOG4105CIH	Imidazole acetol-phosphate transaminase
DD548_14715	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
DD548_14745	ENOG4108JJB	ABC transporter
DD548_14795	ENOG4107QPK	)-transporter
DD548_14800	ENOG4105FR1	rard protein
DD548_14810	ENOG4105D9G	High-affinity
DD548_14825	ENOG4105C19	ABC transporter
DD548_14885	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)