locus-tag	class	description
RK93_000060	COG0860	N-Acetylmuramoyl-L-alanine amidase
RK93_000060	COG1388	LysM domain
RK93_000110	COG1141	Ferredoxin
RK93_000120	COG0514	ATP-dependent DNA helicase (RecQ)
RK93_000135	COG0492	ferredoxin-NADP+ reductase activity
RK93_000200	COG0142	geranyltranstransferase activity
RK93_000240	COG4347	Protein of unknown function (DUF1405)
RK93_000245	COG2738	Putative neutral zinc metallopeptidase
RK93_000250	COG1694	Mazg nucleotide pyrophosphohydrolase
RK93_000255	COG0438	transferase activity, transferring glycosyl groups
RK93_000280	COG3935	DnaD domain protein
RK93_000285	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RK93_000295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RK93_000295	COG4499	WXG100 protein secretion system (Wss), protein YukC
RK93_000335	COG0116	Belongs to the methyltransferase superfamily
RK93_000350	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
RK93_000355	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RK93_000370	COG0531	amino acid
RK93_000395	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RK93_000410	COG1413	lyase activity
RK93_000435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RK93_000465	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RK93_000470	COG0671	phosphoesterase, PA-phosphatase related
RK93_000475	COG1943	Transposase
RK93_000525	COG4548	von Willebrand factor, type A
RK93_000575	COG3328	transposase activity
RK93_000590	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RK93_000615	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RK93_000620	COG0527	aspartate kinase activity
RK93_000625	COG0488	(ABC) transporter
RK93_000645	COG0573	inorganic phosphate transmembrane transporter activity
RK93_000650	COG0581	inorganic phosphate transmembrane transporter activity
RK93_000660	COG0704	Plays a role in the regulation of phosphate uptake
RK93_000705	COG0561	phosphatase activity
RK93_000710	COG2348	transferase activity, transferring amino-acyl groups
RK93_000715	COG2348	transferase activity, transferring amino-acyl groups
RK93_000745	COG0512	Glutamine amidotransferase of anthranilate synthase
RK93_000750	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RK93_000755	COG1363	Peptidase, m42
RK93_000765	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RK93_000775	COG1316	TRANSCRIPTIONal
RK93_000780	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RK93_000785	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
RK93_000785	COG0392	lysyltransferase activity
RK93_000790	COG0628	permease
RK93_000805	COG1115	amino acid carrier protein
RK93_000820	COG0187	DNA topoisomerase II activity
RK93_000845	COG0824	Thioesterase
RK93_000860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RK93_000880	COG4846	Membrane protein involved in cytochrome C biogenesis
RK93_000915	COG2340	Cysteine-rich secretory protein family
RK93_000945	COG0833	amino acid
RK93_000970	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RK93_000975	COG0460	homoserine dehydrogenase
RK93_000980	COG0527	aspartate kinase activity
RK93_000995	COG1525	nuclease
RK93_001005	COG2197	response regulator
RK93_001020	COG1131	(ABC) transporter
RK93_001110	COG1674	ftsk spoiiie
RK93_001120	COG0433	COG0433 Predicted ATPase
RK93_001140	COG2946	Replication initiation factor
RK93_001215	COG0789	Transcriptional regulator
RK93_001220	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
RK93_001235	COG1923	regulation of RNA biosynthetic process
RK93_001260	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RK93_001265	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
RK93_001300	COG1013	pyruvate-flavodoxin oxidoreductase activity
RK93_001305	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
RK93_001305	COG0674	pyruvate-flavodoxin oxidoreductase activity
RK93_001310	COG1692	metallophosphoesterase
RK93_001330	COG1058	Belongs to the CinA family
RK93_001330	COG1546	Belongs to the CinA family
RK93_001350	COG0300	oxidoreductase activity
RK93_001355	COG0612	Peptidase, M16
RK93_001360	COG0612	Peptidase, M16
RK93_001365	COG2188	Transcriptional regulator
RK93_001395	COG0196	riboflavin kinase activity
RK93_001420	COG2740	Nucleic-acid-binding protein implicated in transcription termination
RK93_001425	COG0195	Participates in both transcription termination and antitermination
RK93_001525	COG0758	DNA mediated transformation
RK93_001530	COG2348	transferase activity, transferring amino-acyl groups
RK93_001535	COG3328	transposase activity
RK93_001545	COG1388	LysM domain
RK93_001595	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RK93_001605	COG0552	protein localization to endoplasmic reticulum
RK93_001610	COG1196	nuclear chromosome segregation
RK93_001650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RK93_001660	COG1302	Protein conserved in bacteria
RK93_001675	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RK93_001690	COG0631	protein serine/threonine phosphatase activity
RK93_001700	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RK93_001700	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RK93_001715	COG2314	TM2 domain
RK93_001725	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RK93_001730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RK93_001790	COG2233	PERMEase
RK93_001800	COG0564	pseudouridine synthase activity
RK93_001820	COG2514	catechol 2,3-dioxygenase activity
RK93_001830	COG3599	regulation of cell shape
RK93_001835	COG2302	S4 RNA-binding domain
RK93_001840	COG0762	integral membrane protein
RK93_001850	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RK93_001860	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RK93_001865	COG0849	cell division
RK93_001870	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RK93_001890	COG4839	cell division protein FtsL
RK93_001915	COG1011	Hydrolase
RK93_001950	COG1288	antiporter activity
RK93_002070	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RK93_002075	COG1053	succinate dehydrogenase
RK93_002080	COG2009	succinate dehydrogenase
RK93_002105	COG1796	DNA polymerase
RK93_002105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RK93_002140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RK93_002155	COG4509	Sortase family
RK93_002190	COG5632	N-Acetylmuramoyl-L-alanine amidase
RK93_002190	COG1388	LysM domain
RK93_002320	COG1783	phage Terminase large subunit
RK93_002515	COG0742	ribosomal rna small subunit methyltransferase
RK93_002535	COG3679	Belongs to the UPF0342 family
RK93_002565	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
RK93_002570	COG0772	Belongs to the SEDS family
RK93_002580	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RK93_002600	COG0483	inositol monophosphate 1-phosphatase activity
RK93_002625	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RK93_002630	COG1177	transmembrane transport
RK93_002635	COG1176	ABC-type spermidine putrescine transport system, permease component I
RK93_002700	COG0569	domain protein
RK93_002705	COG1294	oxidase, subunit
RK93_002710	COG1271	oxidase subunit
RK93_002735	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
RK93_002760	COG4721	ABC-type cobalt transport system, permease component
RK93_002765	COG4172	Belongs to the ABC transporter superfamily
RK93_002770	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RK93_002780	COG0138	bifunctional purine biosynthesis protein purh
RK93_002810	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RK93_002825	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RK93_002870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RK93_002875	COG1316	TRANSCRIPTIONal
RK93_002885	COG2153	protein acetylation
RK93_002905	COG3594	Acyltransferase
RK93_002910	COG0436	Aminotransferase
RK93_002915	COG3591	Belongs to the peptidase S1B family
RK93_002935	COG2267	carboxylic ester hydrolase activity
RK93_002945	COG1169	isochorismate synthase
RK93_002955	COG1575	Belongs to the MenA family. Type 1 subfamily
RK93_002960	COG0456	acetyltransferase
RK93_002965	COG2314	TM2 domain
RK93_002975	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RK93_003005	COG3328	transposase activity
RK93_003010	COG3842	ATPase activity
RK93_003045	COG4873	Protein conserved in bacteria
RK93_003060	COG4903	ComK protein
RK93_003075	COG0737	Belongs to the 5'-nucleotidase family
RK93_003080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RK93_003090	COG0861	Integral membrane protein TerC family
RK93_003130	COG1115	amino acid carrier protein
RK93_003135	COG0628	permease
RK93_003145	COG0475	glutathione-regulated potassium exporter activity
RK93_003145	COG0569	domain protein
RK93_003150	COG2239	Acts as a magnesium transporter
RK93_003155	COG0564	pseudouridine synthase activity
RK93_003165	COG2357	RelA SpoT domain protein
RK93_003180	COG2346	COG2346, Truncated hemoglobins
RK93_003190	COG1164	Oligoendopeptidase f
RK93_003220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK93_003225	COG0601	transmembrane transport
RK93_003230	COG4608	Belongs to the ABC transporter superfamily
RK93_003235	COG0444	Belongs to the ABC transporter superfamily
RK93_003240	COG0747	negative chemotaxis
RK93_003245	COG4166	transmembrane transport
RK93_003250	COG4608	Belongs to the ABC transporter superfamily
RK93_003255	COG0444	Belongs to the ABC transporter superfamily
RK93_003260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK93_003265	COG0601	transmembrane transport
RK93_003295	COG1881	PFAM PEBP family protein
RK93_003335	COG0561	phosphatase activity
RK93_003355	COG1074	ATP-dependent DNA helicase activity
RK93_003375	COG0398	Pfam SNARE associated Golgi protein
RK93_003395	COG0584	glycerophosphoryl diester phosphodiesterase
RK93_003415	COG1902	pentaerythritol trinitrate reductase activity
RK93_003420	COG1098	S1 RNA binding domain
RK93_003475	COG2050	protein possibly involved in aromatic compounds catabolism
RK93_003480	COG2056	Na+-H+ antiporter family
RK93_003485	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RK93_003495	COG0316	Belongs to the HesB IscA family
RK93_003505	COG1252	NADH dehydrogenase
RK93_003510	COG4837	Protein of unknown function (DUF1462)
RK93_003515	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RK93_003520	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
RK93_003530	COG1696	Membrane protein involved in D-alanine export
RK93_003560	COG2445	Protein of unknown function DUF86
RK93_003570	COG4470	Protein conserved in bacteria
RK93_003585	COG0730	response to heat
RK93_003590	COG1801	Protein of unknown function DUF72
RK93_003605	COG1253	flavin adenine dinucleotide binding
RK93_003630	COG0822	iron-sulfur transferase activity
RK93_003640	COG0719	Fe-S assembly protein
RK93_003645	COG0396	ATPase activity
RK93_003685	COG5484	DNA packaging
RK93_003685	COG3728	DNA packaging
RK93_003790	COG0582	viral genome integration into host DNA
RK93_003795	COG1464	Belongs to the NlpA lipoprotein family
RK93_003800	COG2011	ABC-type metal ion transport system permease component
RK93_003815	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RK93_003825	COG3878	Protein conserved in bacteria
RK93_003840	COG1393	Belongs to the ArsC family
RK93_003845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RK93_003870	COG1279	arginine transmembrane transporter activity
RK93_003875	COG0406	alpha-ribazole phosphatase activity
RK93_003915	COG1278	Cold shock
RK93_003980	COG1943	Transposase
RK93_003995	COG0557	exoribonuclease II activity
RK93_004000	COG1647	Serine aminopeptidase, S33
RK93_004005	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RK93_004075	COG0391	Required for morphogenesis under gluconeogenic growth conditions
RK93_004135	COG3942	CHAP domain
RK93_004135	COG1388	LysM domain
RK93_004165	COG1040	competence protein
RK93_004170	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
RK93_004180	COG1739	Uncharacterized protein family UPF0029
RK93_004185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RK93_004240	COG4607	ABC-type enterochelin transport system periplasmic component
RK93_004245	COG4604	ABC transporter, ATP-binding protein
RK93_004250	COG4605	iron ion homeostasis
RK93_004255	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK93_004270	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RK93_004275	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RK93_004305	COG3104	oligopeptide transport
RK93_004335	COG1174	glycine betaine transport
RK93_004340	COG1125	glycine betaine transport
RK93_004340	COG0517	IMP dehydrogenase activity
RK93_004350	COG0488	(ABC) transporter
RK93_004380	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RK93_004385	COG0512	Glutamine amidotransferase of anthranilate synthase
RK93_004385	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RK93_004395	COG0720	synthase
RK93_004430	COG0463	Glycosyl transferase, family 2
RK93_004435	COG0656	L-ascorbic acid biosynthetic process
RK93_004440	COG1253	flavin adenine dinucleotide binding
RK93_004445	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RK93_004450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK93_004450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK93_004450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK93_004455	COG1105	Belongs to the carbohydrate kinase PfkB family
RK93_004460	COG1349	DNA-binding transcription factor activity
RK93_004465	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RK93_004500	COG0471	metal ion transport
RK93_004510	COG4989	oxidoreductase activity
RK93_004515	COG0523	cobalamin synthesis protein
RK93_004520	COG1846	Transcriptional regulator
RK93_004525	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
RK93_004530	COG4988	ABC transporter
RK93_004550	COG1611	Belongs to the LOG family
RK93_004580	COG2839	Protein conserved in bacteria
RK93_004585	COG2814	Major facilitator Superfamily
RK93_004595	COG0583	DNA-binding transcription factor activity
RK93_004625	COG4977	sequence-specific DNA binding
RK93_004625	COG1917	Cupin 2, conserved barrel domain protein
RK93_004635	COG3942	CHAP domain
RK93_004635	COG1388	LysM domain
RK93_004640	COG0306	phosphate transporter
RK93_004645	COG1392	Phosphate transport regulator
RK93_004650	COG0577	efflux transmembrane transporter activity
RK93_004655	COG1136	(ABC) transporter
RK93_004695	COG3949	Membrane
RK93_004705	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
RK93_004715	COG2376	Dihydroxyacetone kinase
RK93_004720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK93_004725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK93_004730	COG1120	ATPase activity
RK93_004735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RK93_004745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RK93_004750	COG1132	(ABC) transporter
RK93_004755	COG1686	Belongs to the peptidase S11 family
RK93_004760	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RK93_004765	COG1216	Glycosyl transferase, family 2
RK93_004770	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK93_004775	COG1682	transport, permease protein
RK93_004785	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
RK93_004795	COG1321	iron dependent repressor
RK93_004800	COG1121	(ABC) transporter
RK93_004805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RK93_004810	COG0803	Belongs to the bacterial solute-binding protein 9 family
RK93_004855	COG4974	Belongs to the 'phage' integrase family
RK93_004880	COG2267	carboxylic ester hydrolase activity
RK93_004910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RK93_004950	COG1078	dGTPase activity
RK93_004960	COG0655	NAD(P)H dehydrogenase (quinone) activity
RK93_004965	COG0667	Aldo Keto reductase
RK93_004990	COG3328	transposase activity
RK93_005065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RK93_005085	COG0083	homoserine kinase activity
RK93_005090	COG0095	Lipoate-protein ligase
RK93_005190	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
RK93_005205	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RK93_005250	COG0561	phosphatase activity
RK93_005260	COG1428	Deoxynucleoside kinase
RK93_005265	COG1428	Deoxynucleoside kinase
RK93_005270	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RK93_005305	COG1473	amidohydrolase
RK93_005335	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RK93_005345	COG2813	Specifically methylates the guanine in position
RK93_005375	COG0250	Participates in transcription elongation, termination and antitermination
RK93_005405	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
RK93_005430	COG4956	integral membrane protein (PIN domain superfamily)
RK93_005435	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RK93_005450	COG3880	PFAM UvrB UvrC protein
RK93_005460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RK93_005475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RK93_005550	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RK93_005575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RK93_005590	COG1098	S1 RNA binding domain
RK93_005600	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RK93_005605	COG3956	TIGRFAM MazG family protein
RK93_005610	COG2244	polysaccharide biosynthetic process
RK93_005655	COG0251	oxidation-reduction process
RK93_005660	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RK93_005670	COG4466	Protein conserved in bacteria
RK93_005680	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RK93_005685	COG0084	hydrolase, TatD family'
RK93_005695	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RK93_005705	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
RK93_005715	COG1774	PSP1 C-terminal conserved region
RK93_005720	COG0470	DNA polymerase III
RK93_005725	COG3870	Protein conserved in bacteria
RK93_005735	COG1982	Orn Lys Arg decarboxylase major
RK93_005770	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RK93_005775	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RK93_005795	COG2188	Transcriptional regulator
RK93_005800	COG0366	Alpha amylase catalytic
RK93_005805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK93_005805	COG1263	PTS System
RK93_005815	COG0493	'glutamate synthase
RK93_005820	COG0070	glutamate synthase
RK93_005820	COG0069	glutamate synthase activity
RK93_005820	COG0067	glutamate synthase
RK93_005825	COG0583	DNA-binding transcription factor activity
RK93_005860	COG1464	Belongs to the NlpA lipoprotein family
RK93_005865	COG2011	ABC-type metal ion transport system permease component
RK93_005875	COG0626	cystathionine gamma-synthase activity
RK93_005880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RK93_005885	COG0733	neurotransmitter:sodium symporter activity
RK93_005895	COG1647	Serine aminopeptidase, S33
RK93_005910	COG5609	conserved protein (DUF2294)
RK93_005915	COG3002	Belongs to the UPF0753 family
RK93_005920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RK93_005945	COG0523	cobalamin synthesis protein
RK93_006085	COG3328	transposase activity
RK93_006115	COG3759	membrane
RK93_006160	COG3328	transposase activity
RK93_006190	COG1674	ftsk spoiiie
RK93_006195	COG2946	Replication initiation factor
RK93_006240	COG0741	lytic transglycosylase activity
RK93_006240	COG0791	NLP P60 protein
RK93_006300	COG0582	viral genome integration into host DNA
RK93_006315	COG2233	PERMEase
RK93_006350	COG1823	symporter activity
RK93_006365	COG3634	alkyl hydroperoxide reductase activity
RK93_006425	COG4974	Belongs to the 'phage' integrase family
RK93_006450	COG3728	DNA packaging
RK93_006450	COG5484	DNA packaging
RK93_006560	COG0012	GTP binding
RK93_006565	COG4481	Protein conserved in bacteria
RK93_006570	COG0668	transmembrane transport
RK93_006575	COG1475	DNA binding
RK93_006585	COG0626	cystathionine gamma-synthase activity
RK93_006590	COG0626	cystathionine gamma-synthase activity
RK93_006595	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RK93_006595	COG0646	methionine synthase
RK93_006635	COG1476	TRANSCRIPTIONal
RK93_006645	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RK93_006650	COG0805	protein transport
RK93_006655	COG0672	)-iron permease
RK93_006660	COG2837	iron assimilation
RK93_006665	COG2822	iron ion transport
RK93_006670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RK93_006685	COG0431	NADPH-dependent FMN reductase
RK93_006690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RK93_006695	COG0346	lactoylglutathione lyase activity
RK93_006700	COG2271	Major facilitator Superfamily
RK93_006730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK93_006740	COG3037	sugar-specific permease SgaT UlaA
RK93_006770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RK93_006790	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
RK93_006790	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RK93_006820	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RK93_006825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RK93_006855	COG0577	efflux transmembrane transporter activity
RK93_006865	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
RK93_006875	COG1114	Component of the transport system for branched-chain amino acids
RK93_006970	COG3328	transposase activity
RK93_007025	COG0842	Transport permease protein
RK93_007025	COG1511	domain protein
RK93_007035	COG3942	CHAP domain
RK93_007035	COG1388	LysM domain
RK93_007070	COG0739	heme binding
RK93_007125	COG2226	methyltransferase
RK93_007135	COG2723	6-phospho-beta-galactosidase activity
RK93_007140	COG1263	PTS System
RK93_007140	COG2190	(PTS) system
RK93_007140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK93_007150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RK93_007185	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK93_007190	COG1063	alcohol dehydrogenase
RK93_007200	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK93_007205	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RK93_007210	COG1063	alcohol dehydrogenase
RK93_007215	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RK93_007230	COG1063	alcohol dehydrogenase
RK93_007235	COG3775	system Galactitol-specific IIC component
RK93_007240	COG3414	Phosphotransferase system galactitol-specific IIB component
RK93_007260	COG1957	nucleoside hydrolase
RK93_007265	COG2190	(PTS) system
RK93_007265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK93_007265	COG1263	PTS System
RK93_007300	COG3189	MarR family transcriptional regulator
RK93_007305	COG0747	negative chemotaxis
RK93_007320	COG0318	PFAM AMP-dependent synthetase and ligase
RK93_007325	COG1960	acyl-CoA dehydrogenase activity
RK93_007335	COG0183	Belongs to the thiolase family
RK93_007395	COG1755	Isoprenylcysteine carboxyl methyltransferase
RK93_007405	COG0673	inositol 2-dehydrogenase activity
RK93_007410	COG0673	inositol 2-dehydrogenase activity
RK93_007415	COG3833	ABC-type maltose transport systems, permease component
RK93_007420	COG1175	transmembrane transport
RK93_007430	COG3842	ATPase activity
RK93_007450	COG0405	Gamma-glutamyltransferase
RK93_007460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK93_007500	COG1737	Transcriptional regulator
RK93_007530	COG3961	Belongs to the TPP enzyme family
RK93_007535	COG1335	isochorismatase
RK93_007540	COG1114	Component of the transport system for branched-chain amino acids
RK93_007590	COG5609	conserved protein (DUF2294)
RK93_007595	COG1960	acyl-CoA dehydrogenase activity
RK93_007600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RK93_007635	COG2832	Protein of unknown function (DUF454)
RK93_007645	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RK93_007650	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
RK93_007660	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RK93_007690	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RK93_007700	COG1086	Polysaccharide biosynthesis protein
RK93_007725	COG1012	belongs to the aldehyde dehydrogenase family
RK93_007725	COG1454	alcohol dehydrogenase
RK93_007765	COG0737	Belongs to the 5'-nucleotidase family
RK93_007785	COG3639	organic phosphonate transmembrane transporter activity
RK93_007805	COG2814	Major facilitator Superfamily
RK93_007810	COG0813	purine-nucleoside phosphorylase activity
RK93_007845	COG0438	transferase activity, transferring glycosyl groups
RK93_007850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RK93_007855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RK93_007885	COG1475	DNA binding
RK93_007890	COG0019	diaminopimelate decarboxylase activity
RK93_007900	COG4264	IucA IucC family
RK93_007905	COG4264	IucA IucC family
RK93_007910	COG2814	Major facilitator Superfamily
RK93_007915	COG4264	IucA IucC family
RK93_007920	COG2423	ornithine cyclodeaminase activity
RK93_007930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RK93_007935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK93_007940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK93_007960	COG1620	l-lactate permease
RK93_007975	COG0697	spore germination
RK93_007980	COG4716	Myosin-crossreactive antigen
RK93_007985	COG1283	sodium-dependent phosphate transmembrane transporter activity
RK93_007995	COG1473	amidohydrolase
RK93_008020	COG0823	Involved in the tonB-independent uptake of proteins
RK93_008040	COG0583	DNA-binding transcription factor activity
RK93_008055	COG0655	NAD(P)H dehydrogenase (quinone) activity
RK93_008135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RK93_008140	COG2210	Belongs to the sulfur carrier protein TusA family
RK93_008145	COG1937	Protein conserved in bacteria
RK93_008150	COG0730	response to heat
RK93_008250	COG2602	Beta-lactamase
RK93_008250	COG4219	Peptidase M56
RK93_008260	COG2030	dehydratase
RK93_008265	COG0584	glycerophosphoryl diester phosphodiesterase
RK93_008270	COG3316	Transposase and inactivated derivatives
RK93_008300	COG3316	Transposase and inactivated derivatives
RK93_008320	COG0737	Belongs to the 5'-nucleotidase family
RK93_008330	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RK93_008340	COG4863	YycH protein
RK93_008375	COG0305	Participates in initiation and elongation during chromosome replication
RK93_008385	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
RK93_008395	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RK93_008425	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RK93_008445	COG2501	S4 domain
RK93_008485	COG1475	DNA binding
RK93_008510	COG1278	Cold shock
RK93_008540	COG0577	efflux transmembrane transporter activity
RK93_008545	COG1136	(ABC) transporter
RK93_008560	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
RK93_008570	COG2962	Rard protein
RK93_008575	COG0471	metal ion transport
RK93_008660	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RK93_008695	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
RK93_008705	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
RK93_008710	COG0726	polysaccharide deacetylase
RK93_008720	COG1215	transferase activity, transferring glycosyl groups
RK93_008725	COG1309	transcriptional regulator
RK93_008755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RK93_008775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RK93_008785	COG0201	protein transport
RK93_008795	COG1073	alpha beta
RK93_008810	COG0438	transferase activity, transferring glycosyl groups
RK93_008825	COG3433	isochorismatase activity
RK93_008825	COG1535	isochorismatase
RK93_008830	COG1705	Flagellar rod assembly protein muramidase FlgJ
RK93_008830	COG3942	CHAP domain
RK93_008840	COG1482	cell wall glycoprotein biosynthetic process
RK93_008845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK93_008845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK93_008845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RK93_008850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RK93_008850	COG3711	transcriptional antiterminator
RK93_008880	COG2235	arginine
RK93_008905	COG4932	domain protein
RK93_008905	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
RK93_008915	COG1846	Transcriptional regulator
RK93_008925	COG1785	Belongs to the alkaline phosphatase family
RK93_008935	COG0745	RESPONSE REGULATOR receiver
RK93_008940	COG2205	protein histidine kinase activity
RK93_008945	COG1136	(ABC) transporter
RK93_008970	COG0386	Belongs to the glutathione peroxidase family
RK93_008980	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RK93_008995	COG2851	Citrate transporter
RK93_009020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RK93_009030	COG1510	regulation of RNA biosynthetic process
RK93_009060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RK93_009090	COG0531	amino acid
RK93_009105	COG3527	Alpha-acetolactate decarboxylase
RK93_009110	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RK93_009160	COG0167	dihydroorotate dehydrogenase activity
RK93_009275	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RK93_009275	COG2755	lipolytic protein G-D-S-L family
RK93_009310	COG0436	Aminotransferase
RK93_009325	COG2217	Heavy metal translocating P-type atpase
RK93_009355	COG2409	Drug exporters of the RND superfamily
RK93_009375	COG0542	response to heat
RK93_009380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RK93_009385	COG3425	synthase
RK93_009410	COG3942	CHAP domain
RK93_009420	COG0583	DNA-binding transcription factor activity
RK93_009430	COG1346	cytolysis
RK93_009435	COG0028	Belongs to the TPP enzyme family
RK93_009455	COG0657	acetylesterase activity
RK93_009460	COG0697	spore germination
RK93_009475	COG1760	l-serine dehydratase
RK93_009480	COG1760	l-serine dehydratase
RK93_009500	COG3764	Sortase (surface protein transpeptidase)
RK93_009510	COG1131	(ABC) transporter
RK93_009515	COG0561	phosphatase activity
RK93_009530	COG2514	catechol 2,3-dioxygenase activity
RK93_009540	COG1846	Transcriptional regulator
RK93_009545	COG0346	lactoylglutathione lyase activity
RK93_009550	COG0400	carboxylic ester hydrolase activity
RK93_009570	COG1131	(ABC) transporter
RK93_009585	COG1846	Transcriptional regulator
RK93_009590	COG2814	Major facilitator Superfamily
RK93_009600	COG0586	Pfam SNARE associated Golgi protein
RK93_009605	COG2271	Major facilitator Superfamily
RK93_009615	COG4876	unkown
RK93_009620	COG2357	RelA SpoT domain protein
RK93_009625	COG0789	Transcriptional regulator
RK93_009630	COG1802	Transcriptional regulator
RK93_009635	COG1070	Carbohydrate kinase
RK93_009670	COG1846	Transcriptional regulator
RK93_009675	COG1846	Transcriptional regulator
RK93_009715	COG0494	nUDIX hydrolase
RK93_009810	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RK93_009815	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
RK93_009845	COG0747	negative chemotaxis
RK93_009850	COG0601	transmembrane transport
RK93_009855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RK93_009860	COG0444	Belongs to the ABC transporter superfamily
RK93_009865	COG1124	(ABC) transporter
RK93_009880	COG0069	glutamate synthase activity
RK93_009885	COG4808	Protein conserved in bacteria
RK93_009905	COG1363	Peptidase, m42
RK93_009910	COG4619	ABC transporter
RK93_009915	COG0390	transport system, permease component
RK93_009920	COG2814	Major facilitator Superfamily
RK93_009925	COG2272	Belongs to the type-B carboxylesterase lipase family
RK93_009930	COG0531	amino acid
RK93_009940	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
RK93_009960	COG1174	glycine betaine transport
RK93_009970	COG1174	glycine betaine transport
RK93_009980	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RK93_010005	COG0531	amino acid
RK93_010020	COG1113	amino acid transport
RK93_010040	COG2814	Major facilitator Superfamily
RK93_010050	COG1929	Belongs to the glycerate kinase type-1 family
RK93_010075	COG1132	(ABC) transporter
RK93_010090	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RK93_010095	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RK93_010105	COG0156	8-amino-7-oxononanoate synthase activity
RK93_010155	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RK93_010175	COG2814	Major facilitator Superfamily
RK93_010180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RK93_010185	COG0765	amino acid transport
RK93_010190	COG1126	abc transporter atp-binding protein
RK93_010230	COG0803	Belongs to the bacterial solute-binding protein 9 family
RK93_010230	COG3443	Belongs to the bacterial solute-binding protein 9 family
RK93_010245	COG2116	formate transmembrane transporter activity
RK93_010250	COG0454	-acetyltransferase
RK93_010260	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RK93_010265	COG2146	nitrite reductase [NAD(P)H] activity
RK93_010275	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
RK93_010280	COG1140	nitrate reductase beta subunit
RK93_010290	COG2181	nitrate reductase activity
RK93_010310	COG0789	Transcriptional regulator
RK93_010350	COG3871	stress protein (general stress protein 26)
RK93_010365	COG1263	PTS System
RK93_010365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK93_010380	COG1511	domain protein
RK93_010405	COG0456	acetyltransferase
RK93_010410	COG0604	alcohol dehydrogenase
RK93_010430	COG1620	l-lactate permease
RK93_010500	COG2814	Major facilitator Superfamily
RK93_010510	COG1566	PFAM secretion protein HlyD family protein
RK93_010515	COG2814	Major facilitator Superfamily
RK93_010525	COG0657	acetylesterase activity
RK93_010540	COG0598	Magnesium transport protein CorA
RK93_010550	COG0786	glutamate:sodium symporter activity
RK93_010565	COG3152	Membrane
RK93_010570	COG4152	abc transporter atp-binding protein
RK93_010575	COG1668	transmembrane transport
RK93_010595	COG2258	MOSC domain
RK93_010620	COG0583	DNA-binding transcription factor activity
RK93_010635	COG1473	amidohydrolase
RK93_010640	COG1028	Short-chain dehydrogenase reductase Sdr
RK93_010660	COG1737	Transcriptional regulator
RK93_010665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK93_010665	COG1263	PTS System
RK93_010675	COG0385	Bile acid
RK93_010680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RK93_010700	COG1113	amino acid transport
RK93_010790	COG1757	Na H antiporter
RK93_010800	COG3942	CHAP domain
RK93_010865	COG4413	Urea transporter
RK93_010870	COG1960	acyl-CoA dehydrogenase activity
RK93_010885	COG1268	BioY protein
RK93_010900	COG0725	ABC transporter, periplasmic molybdate-binding protein
RK93_010905	COG4149	molybdate abc transporter
RK93_010910	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
RK93_010915	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RK93_010935	COG1763	Mo-molybdopterin cofactor biosynthetic process
RK93_011010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RK93_011055	COG2252	PERMEase
RK93_011170	COG0201	protein transport
RK93_011260	COG3328	transposase activity
RK93_011265	COG0542	response to heat
RK93_011285	COG0028	Belongs to the TPP enzyme family
RK93_011290	COG3527	Alpha-acetolactate decarboxylase
RK93_011310	COG5492	domain, Protein
RK93_011320	COG0789	Transcriptional regulator
RK93_011325	COG0656	L-ascorbic acid biosynthetic process
RK93_011345	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RK93_011350	COG1349	DNA-binding transcription factor activity
RK93_011395	COG2130	NADP-dependent
RK93_011405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RK93_011435	COG2814	Major facilitator Superfamily
RK93_011440	COG4264	IucA IucC family
RK93_011455	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RK93_011460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK93_011465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RK93_011480	COG1988	membrane-bound metal-dependent
RK93_011490	COG1272	protein, Hemolysin III
RK93_011505	COG2814	Major facilitator Superfamily
RK93_011510	COG0489	protein tyrosine kinase activity
RK93_011585	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
RK93_011615	COG3711	transcriptional antiterminator
RK93_011630	COG1119	ATPase activity
RK93_011635	COG0561	phosphatase activity
RK93_011670	COG0640	Transcriptional regulator
RK93_011675	COG0702	epimerase
RK93_011680	COG1482	cell wall glycoprotein biosynthetic process
RK93_011700	COG0783	Belongs to the Dps family
RK93_011705	COG0813	purine-nucleoside phosphorylase activity
RK93_011755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RK93_011795	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RK93_011820	COG2890	protein-(glutamine-N5) methyltransferase activity
RK93_011825	COG0009	L-threonylcarbamoyladenylate synthase
RK93_011850	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RK93_011925	COG0629	single-stranded DNA binding
RK93_011975	COG1418	mRNA catabolic process
RK93_011985	COG1937	Protein conserved in bacteria
RK93_012000	COG0772	Belongs to the SEDS family
RK93_012010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RK93_012020	COG0745	RESPONSE REGULATOR receiver
RK93_012025	COG2205	protein histidine kinase activity
RK93_012055	COG3428	Bacterial PH domain
RK93_012070	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RK93_012095	COG1366	Belongs to the anti-sigma-factor antagonist family
RK93_012105	COG1191	sigma factor activity
RK93_012110	COG2183	response to ionizing radiation
RK93_012185	COG0028	Belongs to the TPP enzyme family
RK93_012200	COG0802	atpase or kinase
RK93_012205	COG1214	PFAM Peptidase M22, glycoprotease
RK93_012210	COG0456	acetyltransferase
RK93_012220	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RK93_012230	COG0488	(ABC) transporter
RK93_012240	COG2391	methyltransferase activity
RK93_012245	COG0425	Belongs to the sulfur carrier protein TusA family
RK93_012250	COG0004	ammonium transporteR
RK93_012255	COG1609	Transcriptional regulator
RK93_012260	COG1621	beta-fructofuranosidase activity
RK93_012265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RK93_012340	COG3728	DNA packaging
RK93_012340	COG5484	DNA packaging
RK93_012360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RK93_012370	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RK93_012390	COG3568	Endonuclease Exonuclease Phosphatase
RK93_012505	COG1484	DNA-dependent DNA replication
RK93_012645	COG4695	Portal protein
RK93_012700	COG0739	heme binding
RK93_012750	COG1388	LysM domain
RK93_012750	COG5632	N-Acetylmuramoyl-L-alanine amidase
RK93_012775	COG1388	LysM domain
RK93_012775	COG0860	N-Acetylmuramoyl-L-alanine amidase
RK93_012800	COG3568	Endonuclease Exonuclease Phosphatase
RK93_012830	COG1725	Transcriptional regulator
RK93_012845	COG1131	(ABC) transporter
RK93_012900	COG1012	belongs to the aldehyde dehydrogenase family
RK93_012915	COG1335	isochorismatase
RK93_012925	COG0471	metal ion transport
RK93_012935	COG0077	Prephenate dehydratase
RK93_012945	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RK93_012985	COG4496	protein, YerC YecD
RK93_012990	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
RK93_012995	COG0210	DNA helicase
RK93_013005	COG4851	CamS sex pheromone cAM373 precursor
RK93_013135	COG1295	ribonuclease BN
RK93_013155	COG2309	aminopeptidase activity
RK93_013160	COG1607	acyl-coa hydrolase
RK93_013165	COG0535	radical SAM domain protein
RK93_013195	COG1134	teichoic acid transport
RK93_013195	COG1388	LysM domain
RK93_013210	COG1988	membrane-bound metal-dependent
RK93_013235	COG4129	membrane
RK93_013245	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RK93_013250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RK93_013430	COG0765	amino acid transport
RK93_013435	COG1126	abc transporter atp-binding protein
RK93_013440	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RK93_013480	COG0564	pseudouridine synthase activity
RK93_013485	COG4585	Histidine kinase
RK93_013485	COG2203	Gaf domain
RK93_013490	COG2197	response regulator
RK93_013520	COG0420	3'-5' exonuclease activity
RK93_013555	COG0537	adenosine 5'-monophosphoramidase activity
RK93_013560	COG1131	(ABC) transporter
RK93_013765	COG3591	Belongs to the peptidase S1B family
RK93_013890	COG1506	peptidase
RK93_013895	COG1943	Transposase
RK93_013915	COG0656	L-ascorbic acid biosynthetic process
RK93_013925	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RK93_013930	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RK93_013940	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RK93_013970	COG4193	domain, Protein
RK93_013970	COG3266	domain, Protein
RK93_013970	COG5632	N-Acetylmuramoyl-L-alanine amidase
RK93_013995	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RK93_013995	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RK93_014030	COG2267	carboxylic ester hydrolase activity
RK93_014040	COG3328	transposase activity
RK93_014045	COG1846	Transcriptional regulator
RK93_014050	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
RK93_014055	COG1242	4 iron, 4 sulfur cluster binding
RK93_014060	COG2814	Major facilitator Superfamily
RK93_014080	COG2081	HI0933 family
RK93_014085	COG2244	polysaccharide biosynthetic process
RK93_014090	COG1187	pseudouridine synthase activity
RK93_014110	COG0510	thiamine kinase activity
RK93_014125	COG3328	transposase activity
RK93_014130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RK93_014140	COG1363	Peptidase, m42
RK93_014145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RK93_014155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RK93_014160	COG1674	ftsk spoiiie
RK93_014185	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
RK93_014185	COG1605	Chorismate mutase
RK93_014205	COG0454	-acetyltransferase
RK93_014210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RK93_014245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RK93_014250	COG0204	Acyl-transferase
RK93_014255	COG1263	PTS System
RK93_014255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RK93_014270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RK93_014275	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
RK93_014280	COG1764	response to oxidative stress
RK93_014285	COG0584	glycerophosphoryl diester phosphodiesterase
RK93_014305	COG1956	GAF domain-containing protein
RK93_014320	COG1104	cysteine desulfurase activity
RK93_014340	COG0827	DNA restriction-modification system
RK93_014380	COG4109	DRTGG domain
RK93_014390	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RK93_014400	COG0281	malic enzyme
RK93_014430	COG1113	amino acid transport
RK93_014435	COG0372	Belongs to the citrate synthase family
RK93_014450	COG0745	RESPONSE REGULATOR receiver
RK93_014455	COG5002	protein histidine kinase activity
RK93_014465	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RK93_014465	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RK93_014470	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RK93_014495	COG1484	DNA-dependent DNA replication
RK93_014510	COG0833	amino acid
RK93_014535	COG4112	unkown
RK93_014570	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RK93_014585	COG0113	porphobilinogen synthase activity
RK93_014605	COG2818	Glycosylase
RK93_014615	COG0285	dihydrofolate synthase activity
RK93_014625	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RK93_014670	COG2868	ribosomal protein
RK93_014710	COG1862	Preprotein translocase
RK93_014715	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RK93_014715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RK93_014720	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
RK93_014720	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RK93_014765	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RK93_014770	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RK93_014775	COG1959	2 iron, 2 sulfur cluster binding
RK93_014790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RK93_014795	COG1104	cysteine desulfurase activity
RK93_014810	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RK93_014860	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RK93_014865	COG1984	allophanate hydrolase subunit 2
RK93_014870	COG0511	ligase activity, forming carbon-carbon bonds
RK93_014875	COG0439	Biotin carboxylase
RK93_014885	COG1914	H( )-stimulated, divalent metal cation uptake system
RK93_014890	COG3177	Filamentation induced by cAMP protein fic
RK93_014910	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
RK93_014915	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RK93_014925	COG1534	Rna-binding protein
RK93_014935	COG1713	HD superfamily hydrolase involved in NAD metabolism
RK93_014940	COG0799	negative regulation of ribosome biogenesis
RK93_014945	COG2226	methyltransferase
RK93_014955	COG2131	deaminase
RK93_014960	COG2333	competence protein COMEC
RK93_014960	COG0658	competence protein
RK93_014965	COG1466	dna polymerase III delta subunit
RK93_014985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RK93_015015	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RK93_015020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RK93_015030	COG1030	water channel activity
RK93_015045	COG1702	phosphate starvation-inducible protein PhoH
RK93_015060	COG0295	cytidine deaminase activity
RK93_015080	COG0517	IMP dehydrogenase activity
RK93_015095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RK93_015100	COG2384	SAM-dependent methyltransferase
RK93_015110	COG0513	Belongs to the DEAD box helicase family
RK93_015120	COG1121	(ABC) transporter
RK93_015125	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RK93_015130	COG0735	belongs to the Fur family
RK93_015150	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RK93_015160	COG4483	Protein conserved in bacteria
RK93_015165	COG1940	carbohydrate kinase activity
RK93_015170	COG0011	TIGRFAM Protein of
RK93_015175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RK93_015180	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RK93_015185	COG1459	type II secretion system
RK93_015190	COG4537	Required for transformation and DNA binding
RK93_015215	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RK93_015235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RK93_015240	COG0095	Lipoate-protein ligase
RK93_015255	COG0006	proline dipeptidase activity
RK93_015265	COG0511	ligase activity, forming carbon-carbon bonds
RK93_015270	COG0439	Biotin carboxylase
RK93_015275	COG1302	Protein conserved in bacteria
RK93_015305	COG0497	DNA recombination
RK93_015310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RK93_015315	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RK93_015320	COG0022	dehydrogenase e1 component
RK93_015325	COG0508	dehydrogenase complex catalyzes the overall conversion of
RK93_015335	COG4129	membrane
RK93_015345	COG2195	Cleaves the N-terminal amino acid of tripeptides
RK93_015365	COG1609	Transcriptional regulator
RK93_015370	COG0366	Alpha amylase catalytic
RK93_015380	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RK93_015395	COG4221	oxidoreductase activity
RK93_015405	COG0667	Aldo Keto reductase
RK93_015410	COG0494	nUDIX hydrolase
RK93_015415	COG0735	belongs to the Fur family
RK93_015440	COG1187	pseudouridine synthase activity
RK93_015445	COG0745	RESPONSE REGULATOR receiver
RK93_015450	COG5002	protein histidine kinase activity
RK93_015465	COG0582	viral genome integration into host DNA
