locus-tag	class	description
E3S85_00020	COG0740	serine-type endopeptidase activity
E3S85_00070	COG0739	heme binding
E3S85_00115	COG5632	N-Acetylmuramoyl-L-alanine amidase
E3S85_00115	COG1388	LysM domain
E3S85_00125	COG1388	LysM domain
E3S85_00125	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3S85_00170	COG1725	Transcriptional regulator
E3S85_00185	COG1131	(ABC) transporter
E3S85_00235	COG1012	belongs to the aldehyde dehydrogenase family
E3S85_00250	COG1335	isochorismatase
E3S85_00270	COG0077	Prephenate dehydratase
E3S85_00280	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
E3S85_00315	COG4496	protein, YerC YecD
E3S85_00335	COG4851	CamS sex pheromone cAM373 precursor
E3S85_00450	COG1295	ribonuclease BN
E3S85_00470	COG2309	aminopeptidase activity
E3S85_00475	COG1607	acyl-coa hydrolase
E3S85_00480	COG0535	radical SAM domain protein
E3S85_00510	COG1134	teichoic acid transport
E3S85_00510	COG1388	LysM domain
E3S85_00520	COG1988	membrane-bound metal-dependent
E3S85_00525	COG1194	a g-specific adenine glycosylase
E3S85_00540	COG4129	membrane
E3S85_00550	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E3S85_00555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E3S85_00720	COG0765	amino acid transport
E3S85_00725	COG1126	abc transporter atp-binding protein
E3S85_00730	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
E3S85_00760	COG0564	pseudouridine synthase activity
E3S85_00765	COG2203	Gaf domain
E3S85_00765	COG4585	Histidine kinase
E3S85_00770	COG2197	response regulator
E3S85_00790	COG0420	3'-5' exonuclease activity
E3S85_00820	COG0537	adenosine 5'-monophosphoramidase activity
E3S85_00825	COG1131	(ABC) transporter
E3S85_01040	COG5492	domain, Protein
E3S85_01130	COG2816	NAD+ diphosphatase activity
E3S85_01135	COG1506	peptidase
E3S85_01155	COG0656	L-ascorbic acid biosynthetic process
E3S85_01175	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E3S85_01210	COG5632	N-Acetylmuramoyl-L-alanine amidase
E3S85_01210	COG3266	domain, Protein
E3S85_01210	COG4193	domain, Protein
E3S85_01230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3S85_01230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3S85_01260	COG2267	carboxylic ester hydrolase activity
E3S85_01270	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
E3S85_01275	COG1242	4 iron, 4 sulfur cluster binding
E3S85_01280	COG2814	Major facilitator Superfamily
E3S85_01300	COG2081	HI0933 family
E3S85_01305	COG2826	transposase and inactivated derivatives, IS30 family
E3S85_01310	COG2244	polysaccharide biosynthetic process
E3S85_01315	COG1187	pseudouridine synthase activity
E3S85_01335	COG0510	thiamine kinase activity
E3S85_01345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3S85_01355	COG1363	Peptidase, m42
E3S85_01360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E3S85_01370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E3S85_01375	COG1674	ftsk spoiiie
E3S85_01400	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
E3S85_01400	COG1605	Chorismate mutase
E3S85_01420	COG0454	-acetyltransferase
E3S85_01425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3S85_01455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E3S85_01460	COG0204	Acyl-transferase
E3S85_01465	COG1263	PTS System
E3S85_01465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S85_01480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E3S85_01485	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
E3S85_01490	COG1764	response to oxidative stress
E3S85_01495	COG0584	glycerophosphoryl diester phosphodiesterase
E3S85_01510	COG1956	GAF domain-containing protein
E3S85_01525	COG1104	cysteine desulfurase activity
E3S85_01535	COG0730	response to heat
E3S85_01545	COG0827	DNA restriction-modification system
E3S85_01585	COG4109	DRTGG domain
E3S85_01590	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
E3S85_01600	COG0281	malic enzyme
E3S85_01625	COG1113	amino acid transport
E3S85_01630	COG0372	Belongs to the citrate synthase family
E3S85_01640	COG0745	RESPONSE REGULATOR receiver
E3S85_01645	COG5002	protein histidine kinase activity
E3S85_01655	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3S85_01655	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3S85_01685	COG1484	DNA-dependent DNA replication
E3S85_01700	COG0833	amino acid
E3S85_01720	COG4112	unkown
E3S85_01755	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E3S85_01790	COG2818	Glycosylase
E3S85_01800	COG0285	dihydrofolate synthase activity
E3S85_01805	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
E3S85_01850	COG2868	ribosomal protein
E3S85_01890	COG1862	Preprotein translocase
E3S85_01895	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3S85_01895	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3S85_01900	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
E3S85_01900	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E3S85_01945	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E3S85_01950	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E3S85_01955	COG1959	2 iron, 2 sulfur cluster binding
E3S85_01960	COG3237	CsbD-like
E3S85_01970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3S85_01975	COG1104	cysteine desulfurase activity
E3S85_01990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E3S85_02040	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E3S85_02045	COG1984	allophanate hydrolase subunit 2
E3S85_02050	COG0511	ligase activity, forming carbon-carbon bonds
E3S85_02055	COG0439	Biotin carboxylase
E3S85_02065	COG1914	H( )-stimulated, divalent metal cation uptake system
E3S85_02070	COG3177	Filamentation induced by cAMP protein fic
E3S85_02090	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
E3S85_02095	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
E3S85_02105	COG1534	Rna-binding protein
E3S85_02115	COG1713	HD superfamily hydrolase involved in NAD metabolism
E3S85_02120	COG0799	negative regulation of ribosome biogenesis
E3S85_02125	COG2226	methyltransferase
E3S85_02135	COG2131	deaminase
E3S85_02140	COG0658	competence protein
E3S85_02140	COG2333	competence protein COMEC
E3S85_02145	COG1466	dna polymerase III delta subunit
E3S85_02160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E3S85_02190	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E3S85_02195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E3S85_02205	COG1030	water channel activity
E3S85_02220	COG1702	phosphate starvation-inducible protein PhoH
E3S85_02235	COG0295	cytidine deaminase activity
E3S85_02255	COG0517	IMP dehydrogenase activity
E3S85_02275	COG2384	SAM-dependent methyltransferase
E3S85_02285	COG0513	Belongs to the DEAD box helicase family
E3S85_02295	COG1121	(ABC) transporter
E3S85_02300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3S85_02325	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E3S85_02335	COG4483	Protein conserved in bacteria
E3S85_02340	COG1940	carbohydrate kinase activity
E3S85_02345	COG0011	TIGRFAM Protein of
E3S85_02350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3S85_02355	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E3S85_02360	COG1459	type II secretion system
E3S85_02365	COG4537	Required for transformation and DNA binding
E3S85_02410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3S85_02415	COG0095	Lipoate-protein ligase
E3S85_02430	COG0006	proline dipeptidase activity
E3S85_02440	COG0511	ligase activity, forming carbon-carbon bonds
E3S85_02445	COG0439	Biotin carboxylase
E3S85_02450	COG1302	Protein conserved in bacteria
E3S85_02480	COG0497	DNA recombination
E3S85_02485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3S85_02490	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
E3S85_02495	COG0022	dehydrogenase e1 component
E3S85_02500	COG0508	dehydrogenase complex catalyzes the overall conversion of
E3S85_02510	COG4129	membrane
E3S85_02520	COG2195	Cleaves the N-terminal amino acid of tripeptides
E3S85_02550	COG1609	Transcriptional regulator
E3S85_02555	COG0366	Alpha amylase catalytic
E3S85_02565	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E3S85_02580	COG4221	oxidoreductase activity
E3S85_02590	COG0667	Aldo Keto reductase
E3S85_02595	COG0494	nUDIX hydrolase
E3S85_02600	COG0735	belongs to the Fur family
E3S85_02625	COG1187	pseudouridine synthase activity
E3S85_02630	COG0745	RESPONSE REGULATOR receiver
E3S85_02650	COG0582	viral genome integration into host DNA
E3S85_02690	COG3645	SOS response
E3S85_02690	COG3646	Phage regulatory protein
E3S85_02855	COG2826	transposase and inactivated derivatives, IS30 family
E3S85_02895	COG5280	Phage tail tape measure protein TP901
E3S85_02895	COG3953	SLT domain
E3S85_02945	COG1388	LysM domain
E3S85_02945	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3S85_02980	COG1141	Ferredoxin
E3S85_02990	COG0514	ATP-dependent DNA helicase (RecQ)
E3S85_03005	COG0492	ferredoxin-NADP+ reductase activity
E3S85_03060	COG0142	geranyltranstransferase activity
E3S85_03095	COG4347	Protein of unknown function (DUF1405)
E3S85_03100	COG2738	Putative neutral zinc metallopeptidase
E3S85_03105	COG1694	Mazg nucleotide pyrophosphohydrolase
E3S85_03110	COG0438	transferase activity, transferring glycosyl groups
E3S85_03135	COG3935	DnaD domain protein
E3S85_03140	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E3S85_03150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E3S85_03150	COG4499	WXG100 protein secretion system (Wss), protein YukC
E3S85_03180	COG0116	Belongs to the methyltransferase superfamily
E3S85_03195	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
E3S85_03200	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E3S85_03215	COG0531	amino acid
E3S85_03235	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E3S85_03295	COG2826	transposase and inactivated derivatives, IS30 family
E3S85_03315	COG0671	phosphoesterase, PA-phosphatase related
E3S85_03360	COG0714	Associated with various cellular activities
E3S85_03365	COG4548	von Willebrand factor, type A
E3S85_03435	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E3S85_03440	COG0527	aspartate kinase activity
E3S85_03445	COG0488	(ABC) transporter
E3S85_03460	COG0573	inorganic phosphate transmembrane transporter activity
E3S85_03465	COG0581	inorganic phosphate transmembrane transporter activity
E3S85_03475	COG0704	Plays a role in the regulation of phosphate uptake
E3S85_03560	COG0512	Glutamine amidotransferase of anthranilate synthase
E3S85_03565	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3S85_03570	COG1363	Peptidase, m42
E3S85_03580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E3S85_03610	COG0628	permease
E3S85_03625	COG1115	amino acid carrier protein
E3S85_03650	COG0824	Thioesterase
E3S85_03660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3S85_03680	COG4846	Membrane protein involved in cytochrome C biogenesis
E3S85_03745	COG0833	amino acid
E3S85_03770	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E3S85_03775	COG0460	homoserine dehydrogenase
E3S85_03780	COG0527	aspartate kinase activity
E3S85_03795	COG1525	nuclease
E3S85_03805	COG2197	response regulator
E3S85_03820	COG1131	(ABC) transporter
E3S85_03925	COG2826	transposase and inactivated derivatives, IS30 family
E3S85_03960	COG0789	Transcriptional regulator
E3S85_03965	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
E3S85_03980	COG1923	regulation of RNA biosynthetic process
E3S85_04005	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E3S85_04010	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
E3S85_04045	COG1013	pyruvate-flavodoxin oxidoreductase activity
E3S85_04050	COG0674	pyruvate-flavodoxin oxidoreductase activity
E3S85_04050	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E3S85_04055	COG1692	metallophosphoesterase
E3S85_04075	COG1546	Belongs to the CinA family
E3S85_04075	COG1058	Belongs to the CinA family
E3S85_04095	COG0300	oxidoreductase activity
E3S85_04100	COG0612	Peptidase, M16
E3S85_04105	COG0612	Peptidase, M16
E3S85_04110	COG2188	Transcriptional regulator
E3S85_04135	COG0196	riboflavin kinase activity
E3S85_04160	COG2740	Nucleic-acid-binding protein implicated in transcription termination
E3S85_04165	COG0195	Participates in both transcription termination and antitermination
E3S85_04260	COG0758	DNA mediated transformation
E3S85_04265	COG2348	transferase activity, transferring amino-acyl groups
E3S85_04320	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E3S85_04330	COG0552	protein localization to endoplasmic reticulum
E3S85_04335	COG1196	nuclear chromosome segregation
E3S85_04380	COG1302	Protein conserved in bacteria
E3S85_04395	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E3S85_04410	COG0631	protein serine/threonine phosphatase activity
E3S85_04420	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
E3S85_04420	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E3S85_04435	COG2314	TM2 domain
E3S85_04445	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E3S85_04450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E3S85_04465	COG1293	RNA-binding protein homologous to eukaryotic snRNP
E3S85_04510	COG2233	PERMEase
E3S85_04520	COG0564	pseudouridine synthase activity
E3S85_04530	COG2514	catechol 2,3-dioxygenase activity
E3S85_04535	COG2826	transposase and inactivated derivatives, IS30 family
E3S85_04545	COG3599	regulation of cell shape
E3S85_04550	COG2302	S4 RNA-binding domain
E3S85_04555	COG0762	integral membrane protein
E3S85_04565	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E3S85_04605	COG4839	cell division protein FtsL
E3S85_04630	COG1011	Hydrolase
E3S85_04660	COG1288	antiporter activity
E3S85_04770	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E3S85_04775	COG1053	succinate dehydrogenase
E3S85_04780	COG2009	succinate dehydrogenase
E3S85_04805	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
E3S85_04805	COG1796	DNA polymerase
E3S85_04835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E3S85_04850	COG4509	Sortase family
E3S85_04905	COG0742	ribosomal rna small subunit methyltransferase
E3S85_04920	COG0584	glycerophosphoryl diester phosphodiesterase
E3S85_04925	COG3679	Belongs to the UPF0342 family
E3S85_04930	COG2340	Cysteine-rich secretory protein family
E3S85_04955	COG0772	Belongs to the SEDS family
E3S85_04965	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
E3S85_04985	COG0483	inositol monophosphate 1-phosphatase activity
E3S85_05010	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E3S85_05015	COG1177	transmembrane transport
E3S85_05020	COG1176	ABC-type spermidine putrescine transport system, permease component I
E3S85_05085	COG0569	domain protein
E3S85_05090	COG1294	oxidase, subunit
E3S85_05095	COG1271	oxidase subunit
E3S85_05120	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
E3S85_05135	COG4721	ABC-type cobalt transport system, permease component
E3S85_05140	COG4172	Belongs to the ABC transporter superfamily
E3S85_05145	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
E3S85_05185	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
E3S85_05200	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E3S85_05245	COG1316	TRANSCRIPTIONal
E3S85_05275	COG3594	Acyltransferase
E3S85_05280	COG0436	Aminotransferase
E3S85_05305	COG2267	carboxylic ester hydrolase activity
E3S85_05315	COG1169	isochorismate synthase
E3S85_05325	COG1575	Belongs to the MenA family. Type 1 subfamily
E3S85_05330	COG0456	acetyltransferase
E3S85_05335	COG2314	TM2 domain
E3S85_05345	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
E3S85_05405	COG4873	Protein conserved in bacteria
E3S85_05420	COG4903	ComK protein
E3S85_05435	COG0737	Belongs to the 5'-nucleotidase family
E3S85_05440	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E3S85_05450	COG0861	Integral membrane protein TerC family
E3S85_05500	COG1115	amino acid carrier protein
E3S85_05505	COG0628	permease
E3S85_05515	COG0569	domain protein
E3S85_05515	COG0475	glutathione-regulated potassium exporter activity
E3S85_05520	COG2239	Acts as a magnesium transporter
E3S85_05525	COG0564	pseudouridine synthase activity
E3S85_05535	COG2357	RelA SpoT domain protein
E3S85_05550	COG2346	COG2346, Truncated hemoglobins
E3S85_05560	COG1164	Oligoendopeptidase f
E3S85_05595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S85_05605	COG4608	Belongs to the ABC transporter superfamily
E3S85_05610	COG0444	Belongs to the ABC transporter superfamily
E3S85_05620	COG2826	transposase and inactivated derivatives, IS30 family
E3S85_05630	COG4166	transmembrane transport
E3S85_05635	COG4608	Belongs to the ABC transporter superfamily
E3S85_05640	COG0444	Belongs to the ABC transporter superfamily
E3S85_05645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S85_05650	COG0601	transmembrane transport
E3S85_05680	COG1881	PFAM PEBP family protein
E3S85_05720	COG0561	phosphatase activity
E3S85_05765	COG0398	Pfam SNARE associated Golgi protein
E3S85_05785	COG0584	glycerophosphoryl diester phosphodiesterase
E3S85_05800	COG1902	pentaerythritol trinitrate reductase activity
E3S85_05805	COG1098	S1 RNA binding domain
E3S85_05860	COG2050	protein possibly involved in aromatic compounds catabolism
E3S85_05865	COG2056	Na+-H+ antiporter family
E3S85_05870	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
E3S85_05880	COG0316	Belongs to the HesB IscA family
E3S85_05890	COG1252	NADH dehydrogenase
E3S85_05895	COG4837	Protein of unknown function (DUF1462)
E3S85_05900	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
E3S85_05905	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
E3S85_05915	COG1696	Membrane protein involved in D-alanine export
E3S85_05945	COG2445	Protein of unknown function DUF86
E3S85_05955	COG4470	Protein conserved in bacteria
E3S85_05970	COG0730	response to heat
E3S85_05975	COG1801	Protein of unknown function DUF72
E3S85_05985	COG1253	flavin adenine dinucleotide binding
E3S85_06005	COG0822	iron-sulfur transferase activity
E3S85_06015	COG0719	Fe-S assembly protein
E3S85_06020	COG0396	ATPase activity
E3S85_06035	COG1464	Belongs to the NlpA lipoprotein family
E3S85_06040	COG2011	ABC-type metal ion transport system permease component
E3S85_06055	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
E3S85_06060	COG3878	Protein conserved in bacteria
E3S85_06075	COG1393	Belongs to the ArsC family
E3S85_06080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E3S85_06105	COG1279	arginine transmembrane transporter activity
E3S85_06110	COG0406	alpha-ribazole phosphatase activity
E3S85_06150	COG1278	Cold shock
E3S85_06230	COG5484	DNA packaging
E3S85_06230	COG3728	DNA packaging
E3S85_06320	COG0557	exoribonuclease II activity
E3S85_06325	COG1647	Serine aminopeptidase, S33
E3S85_06330	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3S85_06380	COG0281	malic enzyme
E3S85_06395	COG0391	Required for morphogenesis under gluconeogenic growth conditions
E3S85_06450	COG3942	CHAP domain
E3S85_06450	COG1388	LysM domain
E3S85_06475	COG1040	competence protein
E3S85_06480	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
E3S85_06490	COG1739	Uncharacterized protein family UPF0029
E3S85_06495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E3S85_06550	COG4607	ABC-type enterochelin transport system periplasmic component
E3S85_06555	COG4604	ABC transporter, ATP-binding protein
E3S85_06560	COG4605	iron ion homeostasis
E3S85_06565	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S85_06570	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3S85_06575	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3S85_06595	COG3104	oligopeptide transport
E3S85_06620	COG1174	glycine betaine transport
E3S85_06625	COG0517	IMP dehydrogenase activity
E3S85_06625	COG1125	glycine betaine transport
E3S85_06630	COG0514	ATP-dependent DNA helicase (RecQ)
E3S85_06635	COG0488	(ABC) transporter
E3S85_06665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3S85_06670	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E3S85_06670	COG0512	Glutamine amidotransferase of anthranilate synthase
E3S85_06680	COG0720	synthase
E3S85_06715	COG0463	Glycosyl transferase, family 2
E3S85_06720	COG0656	L-ascorbic acid biosynthetic process
E3S85_06725	COG1253	flavin adenine dinucleotide binding
E3S85_06730	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E3S85_06735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S85_06735	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S85_06735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S85_06740	COG1105	Belongs to the carbohydrate kinase PfkB family
E3S85_06745	COG1349	DNA-binding transcription factor activity
E3S85_06750	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E3S85_06785	COG0471	metal ion transport
E3S85_06795	COG4989	oxidoreductase activity
E3S85_06800	COG0523	cobalamin synthesis protein
E3S85_06810	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E3S85_06815	COG4988	ABC transporter
E3S85_06835	COG1611	Belongs to the LOG family
E3S85_06870	COG2839	Protein conserved in bacteria
E3S85_06875	COG2814	Major facilitator Superfamily
E3S85_06880	COG0583	DNA-binding transcription factor activity
E3S85_06910	COG4977	sequence-specific DNA binding
E3S85_06910	COG1917	Cupin 2, conserved barrel domain protein
E3S85_06920	COG3942	CHAP domain
E3S85_06920	COG1388	LysM domain
E3S85_06925	COG0306	phosphate transporter
E3S85_06930	COG1392	Phosphate transport regulator
E3S85_06935	COG0577	efflux transmembrane transporter activity
E3S85_06940	COG1136	(ABC) transporter
E3S85_06955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3S85_06975	COG3949	Membrane
E3S85_06995	COG2376	Dihydroxyacetone kinase
E3S85_07000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S85_07005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S85_07010	COG1120	ATPase activity
E3S85_07015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E3S85_07025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3S85_07030	COG1132	(ABC) transporter
E3S85_07035	COG1686	Belongs to the peptidase S11 family
E3S85_07040	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
E3S85_07050	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S85_07055	COG1682	transport, permease protein
E3S85_07075	COG1321	iron dependent repressor
E3S85_07080	COG1121	(ABC) transporter
E3S85_07085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3S85_07090	COG0803	Belongs to the bacterial solute-binding protein 9 family
E3S85_07100	COG2814	Major facilitator Superfamily
E3S85_07195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S85_07200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3S85_07235	COG1078	dGTPase activity
E3S85_07250	COG0667	Aldo Keto reductase
E3S85_07290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3S85_07310	COG0083	homoserine kinase activity
E3S85_07315	COG0095	Lipoate-protein ligase
E3S85_07420	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
E3S85_07445	COG4932	domain protein
E3S85_07460	COG0561	phosphatase activity
E3S85_07470	COG1428	Deoxynucleoside kinase
E3S85_07475	COG1428	Deoxynucleoside kinase
E3S85_07480	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E3S85_07510	COG1473	amidohydrolase
E3S85_07550	COG2813	Specifically methylates the guanine in position
E3S85_07610	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
E3S85_07630	COG4956	integral membrane protein (PIN domain superfamily)
E3S85_07635	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
E3S85_07650	COG3880	PFAM UvrB UvrC protein
E3S85_07660	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3S85_07675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3S85_07770	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E3S85_07795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E3S85_07810	COG1098	S1 RNA binding domain
E3S85_07820	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E3S85_07825	COG3956	TIGRFAM MazG family protein
E3S85_07830	COG2244	polysaccharide biosynthetic process
E3S85_07870	COG0251	oxidation-reduction process
E3S85_07875	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
E3S85_07885	COG4466	Protein conserved in bacteria
E3S85_07895	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
E3S85_07900	COG0084	hydrolase, TatD family'
E3S85_07910	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E3S85_07920	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
E3S85_07930	COG1774	PSP1 C-terminal conserved region
E3S85_07935	COG0470	DNA polymerase III
E3S85_07940	COG3870	Protein conserved in bacteria
E3S85_07950	COG1982	Orn Lys Arg decarboxylase major
E3S85_07985	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
E3S85_08005	COG2188	Transcriptional regulator
E3S85_08010	COG0366	Alpha amylase catalytic
E3S85_08015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S85_08015	COG1263	PTS System
E3S85_08025	COG0493	'glutamate synthase
E3S85_08030	COG0070	glutamate synthase
E3S85_08030	COG0067	glutamate synthase
E3S85_08030	COG0069	glutamate synthase activity
E3S85_08035	COG0583	DNA-binding transcription factor activity
E3S85_08070	COG1464	Belongs to the NlpA lipoprotein family
E3S85_08075	COG2011	ABC-type metal ion transport system permease component
E3S85_08085	COG0626	cystathionine gamma-synthase activity
E3S85_08090	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E3S85_08095	COG0733	neurotransmitter:sodium symporter activity
E3S85_08105	COG1647	Serine aminopeptidase, S33
E3S85_08120	COG5609	conserved protein (DUF2294)
E3S85_08130	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E3S85_08155	COG0523	cobalamin synthesis protein
E3S85_08290	COG3759	membrane
E3S85_08325	COG2233	PERMEase
E3S85_08355	COG1823	symporter activity
E3S85_08450	COG0012	GTP binding
E3S85_08455	COG4481	Protein conserved in bacteria
E3S85_08460	COG0668	transmembrane transport
E3S85_08465	COG1475	DNA binding
E3S85_08470	COG0626	cystathionine gamma-synthase activity
E3S85_08475	COG0626	cystathionine gamma-synthase activity
E3S85_08480	COG0646	methionine synthase
E3S85_08480	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
E3S85_08510	COG1131	(ABC) transporter
E3S85_08520	COG1476	TRANSCRIPTIONal
E3S85_08530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E3S85_08535	COG0805	protein transport
E3S85_08540	COG0672	)-iron permease
E3S85_08550	COG2822	iron ion transport
E3S85_08555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3S85_08570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3S85_08575	COG0346	lactoylglutathione lyase activity
E3S85_08580	COG2271	Major facilitator Superfamily
E3S85_08600	COG3711	transcriptional antiterminator
E3S85_08605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S85_08615	COG3037	sugar-specific permease SgaT UlaA
E3S85_08645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E3S85_08695	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E3S85_08700	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3S85_08730	COG0577	efflux transmembrane transporter activity
E3S85_08735	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
E3S85_08740	COG1114	Component of the transport system for branched-chain amino acids
E3S85_08885	COG1388	LysM domain
E3S85_08885	COG3942	CHAP domain
E3S85_08905	COG1131	(ABC) transporter
E3S85_08960	COG2226	methyltransferase
E3S85_08965	COG2723	6-phospho-beta-galactosidase activity
E3S85_08970	COG1263	PTS System
E3S85_08970	COG2190	(PTS) system
E3S85_08970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S85_08975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3S85_09015	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S85_09020	COG1063	alcohol dehydrogenase
E3S85_09030	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S85_09035	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E3S85_09040	COG1063	alcohol dehydrogenase
E3S85_09050	COG1063	alcohol dehydrogenase
E3S85_09060	COG1063	alcohol dehydrogenase
E3S85_09065	COG3775	system Galactitol-specific IIC component
E3S85_09070	COG3414	Phosphotransferase system galactitol-specific IIB component
E3S85_09090	COG1957	nucleoside hydrolase
E3S85_09095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S85_09095	COG2190	(PTS) system
E3S85_09095	COG1263	PTS System
E3S85_09120	COG3189	MarR family transcriptional regulator
E3S85_09125	COG0747	negative chemotaxis
E3S85_09145	COG0318	PFAM AMP-dependent synthetase and ligase
E3S85_09150	COG1960	acyl-CoA dehydrogenase activity
E3S85_09160	COG0183	Belongs to the thiolase family
E3S85_09215	COG1755	Isoprenylcysteine carboxyl methyltransferase
E3S85_09225	COG0673	inositol 2-dehydrogenase activity
E3S85_09230	COG0673	inositol 2-dehydrogenase activity
E3S85_09235	COG3833	ABC-type maltose transport systems, permease component
E3S85_09240	COG1175	transmembrane transport
E3S85_09250	COG3842	ATPase activity
E3S85_09265	COG0405	Gamma-glutamyltransferase
E3S85_09275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S85_09305	COG1737	Transcriptional regulator
E3S85_09335	COG3961	Belongs to the TPP enzyme family
E3S85_09340	COG1335	isochorismatase
E3S85_09345	COG1114	Component of the transport system for branched-chain amino acids
E3S85_09395	COG5609	conserved protein (DUF2294)
E3S85_09400	COG1960	acyl-CoA dehydrogenase activity
E3S85_09405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E3S85_09440	COG2832	Protein of unknown function (DUF454)
E3S85_09450	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3S85_09455	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E3S85_09465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E3S85_09495	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3S85_09505	COG1086	Polysaccharide biosynthesis protein
E3S85_09530	COG1454	alcohol dehydrogenase
E3S85_09530	COG1012	belongs to the aldehyde dehydrogenase family
E3S85_09545	COG0737	Belongs to the 5'-nucleotidase family
E3S85_09565	COG3639	organic phosphonate transmembrane transporter activity
E3S85_09585	COG2814	Major facilitator Superfamily
E3S85_09590	COG0813	purine-nucleoside phosphorylase activity
E3S85_09620	COG0438	transferase activity, transferring glycosyl groups
E3S85_09625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E3S85_09630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3S85_09650	COG1475	DNA binding
E3S85_09655	COG0019	diaminopimelate decarboxylase activity
E3S85_09665	COG4264	IucA IucC family
E3S85_09670	COG4264	IucA IucC family
E3S85_09675	COG2814	Major facilitator Superfamily
E3S85_09680	COG4264	IucA IucC family
E3S85_09685	COG2423	ornithine cyclodeaminase activity
E3S85_09695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E3S85_09700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S85_09705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S85_09720	COG1620	l-lactate permease
E3S85_09730	COG4716	Myosin-crossreactive antigen
E3S85_09735	COG1283	sodium-dependent phosphate transmembrane transporter activity
E3S85_09745	COG1473	amidohydrolase
E3S85_09760	COG0823	Involved in the tonB-independent uptake of proteins
E3S85_09795	COG0456	acetyltransferase
E3S85_09815	COG2814	Major facilitator Superfamily
E3S85_09835	COG4268	DNA restriction-modification system
E3S85_09840	COG1401	restriction endodeoxyribonuclease activity
E3S85_09850	COG2826	transposase and inactivated derivatives, IS30 family
E3S85_09875	COG0737	Belongs to the 5'-nucleotidase family
E3S85_09880	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E3S85_09890	COG4863	YycH protein
E3S85_09920	COG0305	Participates in initiation and elongation during chromosome replication
E3S85_09930	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
E3S85_09940	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E3S85_09965	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E3S85_09985	COG2501	S4 domain
E3S85_10025	COG1475	DNA binding
E3S85_10045	COG1278	Cold shock
E3S85_10050	COG1404	Belongs to the peptidase S8 family
E3S85_10075	COG0577	efflux transmembrane transporter activity
E3S85_10080	COG1136	(ABC) transporter
E3S85_10095	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
E3S85_10105	COG2962	Rard protein
E3S85_10110	COG0471	metal ion transport
E3S85_10190	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
E3S85_10275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E3S85_10300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E3S85_10320	COG1073	alpha beta
E3S85_10335	COG0438	transferase activity, transferring glycosyl groups
E3S85_10350	COG1535	isochorismatase
E3S85_10350	COG3433	isochorismatase activity
E3S85_10355	COG1705	Flagellar rod assembly protein muramidase FlgJ
E3S85_10355	COG3942	CHAP domain
E3S85_10365	COG1482	cell wall glycoprotein biosynthetic process
E3S85_10370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S85_10370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S85_10370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E3S85_10375	COG3711	transcriptional antiterminator
E3S85_10375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3S85_10395	COG1438	arginine binding
E3S85_10440	COG1846	Transcriptional regulator
E3S85_10450	COG1785	Belongs to the alkaline phosphatase family
E3S85_10460	COG0745	RESPONSE REGULATOR receiver
E3S85_10465	COG2205	protein histidine kinase activity
E3S85_10470	COG1136	(ABC) transporter
E3S85_10490	COG0386	Belongs to the glutathione peroxidase family
E3S85_10500	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
E3S85_10515	COG2851	Citrate transporter
E3S85_10540	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3S85_10545	COG1510	regulation of RNA biosynthetic process
E3S85_10555	COG1012	belongs to the aldehyde dehydrogenase family
E3S85_10575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E3S85_10605	COG0531	amino acid
E3S85_10615	COG3527	Alpha-acetolactate decarboxylase
E3S85_10670	COG0167	dihydroorotate dehydrogenase activity
E3S85_10675	COG3001	Fructosamine kinase
E3S85_10810	COG0436	Aminotransferase
E3S85_10855	COG2409	Drug exporters of the RND superfamily
E3S85_10880	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E3S85_10885	COG3425	synthase
E3S85_10895	COG3942	CHAP domain
E3S85_10905	COG0583	DNA-binding transcription factor activity
E3S85_10920	COG0028	Belongs to the TPP enzyme family
E3S85_10940	COG0657	acetylesterase activity
E3S85_10945	COG0697	spore germination
E3S85_10960	COG1760	l-serine dehydratase
E3S85_10965	COG1760	l-serine dehydratase
E3S85_10985	COG3764	Sortase (surface protein transpeptidase)
E3S85_10990	COG0561	phosphatase activity
E3S85_11010	COG2514	catechol 2,3-dioxygenase activity
E3S85_11020	COG1846	Transcriptional regulator
E3S85_11025	COG0346	lactoylglutathione lyase activity
E3S85_11030	COG0400	carboxylic ester hydrolase activity
E3S85_11050	COG1131	(ABC) transporter
E3S85_11055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E3S85_11065	COG1279	arginine transmembrane transporter activity
E3S85_11070	COG0586	Pfam SNARE associated Golgi protein
E3S85_11075	COG2271	Major facilitator Superfamily
E3S85_11085	COG4876	unkown
E3S85_11090	COG2357	RelA SpoT domain protein
E3S85_11095	COG0789	Transcriptional regulator
E3S85_11100	COG1802	Transcriptional regulator
E3S85_11105	COG1070	Carbohydrate kinase
E3S85_11155	COG0494	nUDIX hydrolase
E3S85_11230	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E3S85_11235	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
E3S85_11240	COG1028	Short-chain dehydrogenase reductase Sdr
E3S85_11245	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
E3S85_11265	COG0747	negative chemotaxis
E3S85_11270	COG0601	transmembrane transport
E3S85_11275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E3S85_11285	COG1124	(ABC) transporter
E3S85_11300	COG0069	glutamate synthase activity
E3S85_11305	COG4808	Protein conserved in bacteria
E3S85_11320	COG1363	Peptidase, m42
E3S85_11325	COG4619	ABC transporter
E3S85_11330	COG0390	transport system, permease component
E3S85_11335	COG2814	Major facilitator Superfamily
E3S85_11340	COG2272	Belongs to the type-B carboxylesterase lipase family
E3S85_11345	COG0531	amino acid
E3S85_11350	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
E3S85_11370	COG1174	glycine betaine transport
E3S85_11380	COG1174	glycine betaine transport
E3S85_11390	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E3S85_11405	COG0531	amino acid
E3S85_11415	COG1113	amino acid transport
E3S85_11435	COG2814	Major facilitator Superfamily
E3S85_11445	COG1929	Belongs to the glycerate kinase type-1 family
E3S85_11465	COG1132	(ABC) transporter
E3S85_11475	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
E3S85_11480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E3S85_11490	COG0156	8-amino-7-oxononanoate synthase activity
E3S85_11530	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
E3S85_11545	COG2814	Major facilitator Superfamily
E3S85_11550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3S85_11555	COG0765	amino acid transport
E3S85_11560	COG1126	abc transporter atp-binding protein
E3S85_11595	COG0803	Belongs to the bacterial solute-binding protein 9 family
E3S85_11595	COG3443	Belongs to the bacterial solute-binding protein 9 family
E3S85_11610	COG2116	formate transmembrane transporter activity
E3S85_11615	COG0454	-acetyltransferase
E3S85_11625	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E3S85_11630	COG2146	nitrite reductase [NAD(P)H] activity
E3S85_11640	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E3S85_11645	COG1140	nitrate reductase beta subunit
E3S85_11655	COG2181	nitrate reductase activity
E3S85_11675	COG0789	Transcriptional regulator
E3S85_11715	COG3871	stress protein (general stress protein 26)
E3S85_11730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S85_11730	COG1263	PTS System
E3S85_11745	COG1511	domain protein
E3S85_11770	COG0604	alcohol dehydrogenase
E3S85_11790	COG1620	l-lactate permease
E3S85_11805	COG1131	(ABC) transporter
E3S85_11865	COG2814	Major facilitator Superfamily
E3S85_11880	COG1566	PFAM secretion protein HlyD family protein
E3S85_11885	COG2814	Major facilitator Superfamily
E3S85_11895	COG0657	acetylesterase activity
E3S85_11910	COG0598	Magnesium transport protein CorA
E3S85_11920	COG0786	glutamate:sodium symporter activity
E3S85_11935	COG4152	abc transporter atp-binding protein
E3S85_11940	COG1668	transmembrane transport
E3S85_11960	COG2258	MOSC domain
E3S85_11985	COG0583	DNA-binding transcription factor activity
E3S85_12000	COG1473	amidohydrolase
E3S85_12005	COG1028	Short-chain dehydrogenase reductase Sdr
E3S85_12025	COG1737	Transcriptional regulator
E3S85_12030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3S85_12030	COG1263	PTS System
E3S85_12040	COG0385	Bile acid
E3S85_12045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3S85_12065	COG1113	amino acid transport
E3S85_12130	COG3942	CHAP domain
E3S85_12145	COG1757	Na H antiporter
E3S85_12215	COG4413	Urea transporter
E3S85_12220	COG1960	acyl-CoA dehydrogenase activity
E3S85_12235	COG1268	BioY protein
E3S85_12250	COG0725	ABC transporter, periplasmic molybdate-binding protein
E3S85_12255	COG4149	molybdate abc transporter
E3S85_12260	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
E3S85_12265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E3S85_12285	COG1763	Mo-molybdopterin cofactor biosynthetic process
E3S85_12345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3S85_12390	COG2252	PERMEase
E3S85_12505	COG0201	protein transport
E3S85_12595	COG0028	Belongs to the TPP enzyme family
E3S85_12600	COG3527	Alpha-acetolactate decarboxylase
E3S85_12620	COG5492	domain, Protein
E3S85_12630	COG0789	Transcriptional regulator
E3S85_12635	COG0656	L-ascorbic acid biosynthetic process
E3S85_12710	COG2130	NADP-dependent
E3S85_12720	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E3S85_12745	COG2814	Major facilitator Superfamily
E3S85_12750	COG4264	IucA IucC family
E3S85_12755	COG3457	Alanine racemase
E3S85_12765	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
E3S85_12770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S85_12775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3S85_12790	COG1988	membrane-bound metal-dependent
E3S85_12800	COG1272	protein, Hemolysin III
E3S85_12815	COG2814	Major facilitator Superfamily
E3S85_12820	COG0489	protein tyrosine kinase activity
E3S85_12880	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
E3S85_12910	COG3711	transcriptional antiterminator
E3S85_12925	COG1119	ATPase activity
E3S85_12930	COG0561	phosphatase activity
E3S85_12955	COG0640	Transcriptional regulator
E3S85_12960	COG0702	epimerase
E3S85_12965	COG1482	cell wall glycoprotein biosynthetic process
E3S85_12985	COG0783	Belongs to the Dps family
E3S85_12990	COG0813	purine-nucleoside phosphorylase activity
E3S85_13035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3S85_13075	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
E3S85_13095	COG2890	protein-(glutamine-N5) methyltransferase activity
E3S85_13100	COG0009	L-threonylcarbamoyladenylate synthase
E3S85_13125	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3S85_13200	COG0629	single-stranded DNA binding
E3S85_13245	COG1418	mRNA catabolic process
E3S85_13255	COG1937	Protein conserved in bacteria
E3S85_13275	COG0772	Belongs to the SEDS family
E3S85_13285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E3S85_13295	COG0745	RESPONSE REGULATOR receiver
E3S85_13300	COG2205	protein histidine kinase activity
E3S85_13330	COG3428	Bacterial PH domain
E3S85_13360	COG2208	phosphoserine phosphatase activity
E3S85_13365	COG1366	Belongs to the anti-sigma-factor antagonist family
E3S85_13375	COG1191	sigma factor activity
E3S85_13380	COG2183	response to ionizing radiation
E3S85_13455	COG0028	Belongs to the TPP enzyme family
E3S85_13470	COG0802	atpase or kinase
E3S85_13475	COG1214	PFAM Peptidase M22, glycoprotease
E3S85_13480	COG0456	acetyltransferase
E3S85_13500	COG0488	(ABC) transporter
E3S85_13510	COG2391	methyltransferase activity
E3S85_13515	COG0425	Belongs to the sulfur carrier protein TusA family
E3S85_13520	COG0004	ammonium transporteR
E3S85_13525	COG1609	Transcriptional regulator
E3S85_13530	COG1621	beta-fructofuranosidase activity
E3S85_13535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E3S85_13610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E3S85_13890	COG3682	Transcriptional regulator
E3S85_13925	COG0577	efflux transmembrane transporter activity
E3S85_13925	COG1136	(ABC) transporter