locus-tag class description ASL17_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) ASL17_00015 ENOG410848D S4 domain protein YaaA ASL17_00035 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) ASL17_00060 ENOG4105DWV Homoserine O-trans-acetylase ASL17_00070 ENOG4105BZR domain protein ASL17_00080 ENOG4105CDU Replicative dna helicase ASL17_00085 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis ASL17_00120 ENOG4105Q2H domain protein ASL17_00125 ENOG4105CGH 5'-nucleotidase ASL17_00150 ENOG4105C2M dna polymerase I ASL17_00170 ENOG4108RS6 transposase ASL17_00190 ENOG410826E Dna repair protein radc ASL17_00195 ENOG4108FPN Integrase ASL17_00205 ENOG4108KU9 integrase family ASL17_00210 ENOG4105ZX1 Transposase C ASL17_00215 ENOG4106JUT Streptomycin 3''-adenylyltransferase ASL17_00220 ENOG41071EZ rRNA adenine N-6-methyltransferase ASL17_00225 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) ASL17_00320 ENOG4108PCX Major Facilitator ASL17_00325 ENOG4106PHI plasmid recombination enzyme ASL17_00350 ENOG4108QXE glycerophosphoryl diester phosphodiesterase ASL17_00355 ENOG4108ZMQ domain protein ASL17_00360 ENOG4107RVG penicillin-binding protein ASL17_00365 ENOG4105CCN Peptidase M56 ASL17_00385 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) ASL17_00390 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase ASL17_00395 ENOG4105XTG Pfam:DUF156 ASL17_00400 ENOG41087NI Sulfite exporter TauE/SafE ASL17_00420 ENOG4105ZX1 Transposase C ASL17_00430 ENOG410826E Dna repair protein radc ASL17_00490 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 ASL17_00495 ENOG4107SQC 5-methylcytosine-specific restriction enzyme subunit McrC ASL17_00535 ENOG4108YM7 Gcn5-related n-acetyltransferase ASL17_00570 ENOG4108NQ3 Phosphatidylinositol-specific phospholipase C ASL17_00590 ENOG4105C57 major facilitator superfamily ASL17_00600 ENOG4105CCI Myosin-Cross-Reactive Antigen ASL17_00615 ENOG4106I9N Immunoglobulin G binding protein A ASL17_00625 ENOG4108IHU transport system permease protein ASL17_00630 ENOG4105DQ5 transport system permease protein ASL17_00635 ENOG4108MES Periplasmic binding protein ASL17_00645 ENOG4105CIF Ornithine Cyclodeaminase ASL17_00650 ENOG4105DJU Siderophore biosynthesis protein ASL17_00655 ENOG4105C6X Major Facilitator ASL17_00660 ENOG4105DBM Siderophore biosynthesis protein ASL17_00665 ENOG4105DUU IucA IucC family protein ASL17_00675 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) ASL17_00680 ENOG41067FT ParB-like nuclease domain ASL17_00695 ENOG4105CHR reductase ASL17_00705 ENOG4108IAJ Nad-dependent epimerase dehydratase ASL17_00715 ENOG4105CPK Glycosyl transferase (Group 1 ASL17_00750 ENOG4105D3A purine nucleoside phosphorylase DeoD-type ASL17_00755 ENOG4108J8C transporter major facilitator family protein ASL17_00795 ENOG4105CGH 5'-nucleotidase ASL17_00810 ENOG4108EKI Dehydrogenase ASL17_00835 ENOG4105C5E polysaccharide biosynthesis protein ASL17_00845 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase ASL17_00875 ENOG4105D3Q Sugar transferase ASL17_00890 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase ASL17_00900 ENOG4105WD1 Membrane ASL17_00910 ENOG4105PGM cation diffusion facilitator family transporter ASL17_00940 ENOG4105C1G acyl-Coa dehydrogenase ASL17_00945 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) ASL17_00995 ENOG4105CWM branched-chain amino acid transport system II carrier protein ASL17_01000 ENOG4105D3W isochorismatase ASL17_01005 ENOG4107RA9 decarboxylase ASL17_01035 ENOG4105QEK Transcriptional regulator ASL17_01060 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component ASL17_01065 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component ASL17_01075 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) ASL17_01105 ENOG4105EG2 ABC transporter, permease ASL17_01115 ENOG4105CK5 oxidoreductase ASL17_01125 ENOG4108WWS isoprenylcysteine carboxyl methyltransferase ASL17_01130 ENOG4105CXY transporter ASL17_01190 ENOG4105CHU acetyl-coa acetyltransferase ASL17_01195 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase ASL17_01200 ENOG4105C1G acyl-Coa dehydrogenase ASL17_01210 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) ASL17_01225 ENOG4107RRN ABC transporter substrate-binding protein ASL17_01230 ENOG4105K78 MarR family Transcriptional regulator ASL17_01260 ENOG4105CI1 PTS System ASL17_01265 ENOG4105DU0 nucleoside hydrolase ASL17_01285 ENOG4105K18 The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) ASL17_01290 ENOG4105DT3 PTS system, galactitol-specific IIc component ASL17_01295 ENOG4105CPQ Dehydrogenase ASL17_01305 ENOG4105CPQ Dehydrogenase ASL17_01315 ENOG4105EJJ Dehydrogenase ASL17_01320 ENOG4107RZX Teichoic acid biosynthesis protein ASL17_01330 ENOG4107SJB teichoic acid biosynthesis ASL17_01340 ENOG4105EJJ Dehydrogenase ASL17_01345 ENOG4107RZX Teichoic acid biosynthesis protein ASL17_01380 ENOG4105DSQ Nitric oxide reductase ASL17_01390 ENOG4105CI1 PTS System ASL17_01395 ENOG4105CS2 ec 3.2.1.21 ASL17_01405 ENOG4105DVA methyltransferase ASL17_01425 ENOG4105EV1 Ribose uptake protein RbsU ASL17_01460 ENOG4105DA5 (ABC) transporter ASL17_01480 ENOG4105VRS hydrolase family 18 ASL17_01500 ENOG4106GSS Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host. Negative regulator of EsaC, which is a secretion substrate of the Ess pathway in many Staphylococcus strains. Not necessary for the production and secretion of EsxA or EsxB (By similarity) ASL17_01625 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family ASL17_01635 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) ASL17_01660 ENOG4105D9N nucleoside ASL17_01665 ENOG4107RJ1 sodium solute ASL17_01675 ENOG41061DF Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity) ASL17_01680 ENOG4106KNT transcriptional regulator ASL17_01690 ENOG4105DWD nucleoside recognition domain protein ASL17_01990 ENOG4108FQ0 the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis ASL17_02010 ENOG4105ZMJ n-acetylmuramoyl-l-alanine amidase ASL17_02030 ENOG4105DEN Luciferase family ASL17_02055 ENOG4105CMR udp-glucose 4-epimerase ASL17_02060 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC ASL17_02070 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia ASL17_02075 ENOG4105CID antiterminator ASL17_02095 ENOG4105CXY transporter ASL17_02110 ENOG4107V0Z fmn reductase ASL17_02115 ENOG4105HMI Membrane ASL17_02135 ENOG4105DBE peroxidase ASL17_02140 ENOG4107SJW iron permease, FTR1 ASL17_02145 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) ASL17_02150 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) ASL17_02160 ENOG4105VZ8 Transcriptional regulator ASL17_02170 ENOG4105DA5 (ABC) transporter ASL17_02210 ENOG4105C28 cystathionine ASL17_02215 ENOG4105C28 cystathionine ASL17_02220 ENOG4105FA0 parb-like partition protein ASL17_02225 ENOG4105D8X mechanosensitive ion channel ASL17_02230 ENOG4105VDK protein, conserved in bacteria ASL17_02235 ENOG4105C3G gtp-binding protein ASL17_02250 ENOG4108UUM single-stranded DNA-binding protein ASL17_02330 ENOG4108JU3 Alkyl hydroperoxide reductase ASL17_02345 ENOG4107R6U sodium dicarboxylate symporter ASL17_02375 ENOG4105C2W permease ASL17_02390 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) ASL17_02415 ENOG4105D59 Tetracycline resistance protein ASL17_02425 ENOG4105K4H Nlp p60 protein ASL17_02495 ENOG4106128 DNA-binding helix-turn-helix protein ASL17_02500 ENOG4106BHR ftsk SpoIIIE family protein ASL17_02555 ENOG4105KA3 membrAne ASL17_02695 ENOG4105CKI cobalamin synthesis protein ASL17_02705 ENOG4108TWJ NADH dehydrogenase subunit 5 ASL17_02710 ENOG4105EVH UPF0753 protein ASL17_02715 ENOG4105GPN Uncharacterized conserved protein (DUF2294) ASL17_02740 ENOG4105C8J )-transporter ASL17_02750 ENOG4105C28 cystathionine ASL17_02760 ENOG4108UMI ABC transporter, permease ASL17_02765 ENOG4105D01 (LipO)protein ASL17_02805 ENOG4105CBC glutamate synthase ASL17_02810 ENOG4105BZ8 glutamate synthase ASL17_02820 ENOG4105C5Y PTS System ASL17_02825 ENOG4105CG3 alpha amylase, catalytic region ASL17_02830 ENOG4107414 GntR family transcriptional regulator ASL17_02855 ENOG4105C6E dna polymerase iii ASL17_02860 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) ASL17_02890 ENOG4105CXN decarboxylase ASL17_02900 ENOG4105X0R protein from nitrogen regulatory protein P-II ASL17_02910 ENOG4105FA2 dna polymerase iii ASL17_02915 ENOG4105MA4 psp1 domain protein ASL17_02925 ENOG41060K3 Methyltransferase ASL17_02935 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) ASL17_02945 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) ASL17_02950 ENOG4105F8V Hydrolase, tatD family ASL17_02955 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) ASL17_02965 ENOG4105W42 Veg protein ASL17_02975 ENOG4105DFT pur operon repressor ASL17_02980 ENOG4105KME endoribonuclease L-psp ASL17_03000 ENOG4105C5T Phosphoribosyl pyrophosphate synthase ASL17_03030 ENOG4108IY2 MazG family ASL17_03035 ENOG41082I2 s4 domain protein ASL17_03045 ENOG41060GV RNA binding s1 domain protein ASL17_03050 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) ASL17_03055 ENOG4108UGV hypoxanthine phosphoribosyltransferase ASL17_03060 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) ASL17_03070 ENOG4105C6T cysteine synthase ASL17_03080 ENOG4105KRF dihydroneopterin aldolase ASL17_03085 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase ASL17_03165 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family ASL17_03180 ENOG4105D9N nucleoside ASL17_03190 ENOG4108Z0C Uvrb UvrC protein ASL17_03210 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) ASL17_03215 ENOG4105CTP PilT protein domain protein ASL17_03235 ENOG4105KEB Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) ASL17_03240 ENOG4105C2N RNA methyltransferase TrmH family group 3 ASL17_03255 ENOG410683Z Preprotein translocase SecE subunit ASL17_03260 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) ASL17_03285 ENOG4107Y49 methyltransferase ASL17_03295 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) ASL17_03330 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) ASL17_03350 ENOG4105CM2 brancheD-chain amino acid aminotransferase ASL17_03355 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase ASL17_03360 ENOG4105ZMH deoxynucleoside kinase ASL17_03370 ENOG4108Z6B deaminase ASL17_03375 ENOG410667J hydrolase ASL17_03385 ENOG4105DUY Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein ASL17_03415 ENOG4107YEI lmbE family ASL17_03430 ENOG4108VA3 3-hexulose-6-phosphate synthase ASL17_03515 ENOG4108IJ2 phosphate acetyltransferase ASL17_03520 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) ASL17_03525 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) ASL17_03545 ENOG4107QN2 dihydrolipoyl dehydrogenase ASL17_03630 ENOG4105CPC Aldo Keto reductase ASL17_03635 ENOG4108WS4 fmn reductase ASL17_03645 ENOG4105DCI Phosphohydrolase ASL17_03650 ENOG4108XFG YwhD family ASL17_03680 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) ASL17_03685 ENOG4108IU2 vtamin B12-transporter permease ASL17_03710 ENOG4108MEZ Alpha beta hydrolase ASL17_03735 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off ASL17_03775 ENOG4105EEQ Na H antiporter ASL17_03780 ENOG4105DSE periplasmic solute binding protein ASL17_03785 ENOG4105CC5 ABC transporter ASL17_03790 ENOG4105DIK (ABC) transporter ASL17_03795 ENOG4107R5H iron (metal) dependent repressor, dtxr family ASL17_03805 ENOG4108UHC Glycosyl transferase, wecb taga cpsf family ASL17_03830 ENOG4107YSK Glycerol-3-phosphate cytidylyltransferase ASL17_03840 ENOG4105BZ1 (ABC) transporter ASL17_03855 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) ASL17_03860 ENOG4105E0A ABC, transporter ASL17_03865 ENOG4105DQ5 transport system permease protein ASL17_03870 ENOG4105EHG Permease protein ASL17_03875 ENOG4105CMT Dihydroxyacetone kinase ASL17_03885 ENOG4105VDH Dihydroxyacetone kinase ASL17_03895 ENOG4108K88 Membrane ASL17_03935 ENOG4105C19 ABC transporter ASL17_03945 ENOG4107GRR phosphate transport regulator ASL17_03950 ENOG4105CJ3 phosphate transporter ASL17_03955 ENOG4105VRS hydrolase family 18 ASL17_03965 ENOG4105ID8 Transcriptional regulator, ARAC family ASL17_04005 ENOG4105S8Q sugar efflux transporter ASL17_04010 ENOG4105SXS Protein of unknown function (DUF456) ASL17_04035 ENOG4108YYQ gCN5-related N-acetyltransferase ASL17_04040 ENOG4108URH decarboxylase ASL17_04060 ENOG4108JJ9 ABC, transporter ASL17_04065 ENOG4108JJ8 (ABC) transporter ASL17_04070 ENOG41083AI transcriptional regulator), MarR family ASL17_04075 ENOG4105CKI cobalamin synthesis protein ASL17_04080 ENOG4107QM2 Aldo Keto reductase ASL17_04090 ENOG4107QPK )-transporter ASL17_04095 ENOG4105CVP deoxyribo-dipyrimidine photolyase ASL17_04115 ENOG4105DP8 Major facilitator superfamily MFS_1 ASL17_04125 ENOG4108Z66 YbaK ebsC protein ASL17_04130 ENOG4105E98 transcriptional regulator DeoR family ASL17_04135 ENOG4105DE4 1-phosphofructokinase ASL17_04140 ENOG4105DM4 PTS System ASL17_04150 ENOG4105CE4 GlcNAc 6-P deacetylase ASL17_04155 ENOG4105C37 (CBS) domain ASL17_04165 ENOG4105CKK Glycosyl transferase, family 2 ASL17_04195 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) ASL17_04200 ENOG4107ZAE 6-carboxy-5,6,7,8-tetrahydropterin synthase ASL17_04210 ENOG4105DDQ anthranilate synthase ASL17_04215 ENOG4105CRQ synthase (Component I) ASL17_04250 ENOG4105C5H ABC transporter ASL17_04255 ENOG4105C9U ATP-dependent DNA helicase RecQ ASL17_04260 ENOG4108IJ8 ABC transporter ASL17_04265 ENOG4105E90 ABC transporter ASL17_04275 ENOG4108ZIE 5 nucleotidase deoxy cytosolic type C ASL17_04295 ENOG4105DUX Transporter ASL17_04315 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) ASL17_04320 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) ASL17_04335 ENOG4105DHS permease protein ASL17_04340 ENOG4105CM4 permease protein ASL17_04345 ENOG4108IPW abc transporter atp-binding protein ASL17_04405 ENOG4105ESV Glycosyl transferase, family 4 ASL17_04410 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein ASL17_04425 ENOG41081UC Inherit from COG: Competence protein ASL17_04455 ENOG41068JE domain protein ASL17_04470 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) ASL17_04475 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) ASL17_04490 ENOG4108S4C acetyltransferase ASL17_04500 ENOG4105C3M thioredoxin reductase ASL17_04515 ENOG4105CHW UPF0052 protein ASL17_04550 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase ASL17_04565 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) ASL17_04580 ENOG4105XZU Preprotein translocase, subunit SecG ASL17_04590 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) ASL17_04645 ENOG4106HV3 Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps ASL17_04645 ENOG4106HV3 Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps ASL17_04665 ENOG4107Y9E nuclease ASL17_04670 ENOG4105VEQ Cold shock protein ASL17_04710 ENOG4105CVJ phosphoglycerate mutase ASL17_04715 ENOG4108ZUB Lysine exporter protein (Lyse ygga) ASL17_04740 ENOG4105SZ6 Thioredoxin ASL17_04745 ENOG41080E8 Transcriptional regulator, Spx MgsR family ASL17_04760 ENOG4108XI2 Domain of unknown function (DUF1963) ASL17_04785 ENOG4108UMI ABC transporter, permease ASL17_04790 ENOG4105D01 (LipO)protein ASL17_04890 ENOG4108TFU terminase (Small subunit) ASL17_04920 ENOG4105C3K feS assembly ATPase SufC ASL17_04925 ENOG4105JRK feS assembly protein SufD ASL17_04930 ENOG4105C9B Cysteine desulfurase ASL17_04935 ENOG4108UNV SUF system FeS assembly protein, NifU family ASL17_04990 ENOG4105MMD transcriptional regulator ASL17_05030 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein ASL17_05040 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD ASL17_05045 ENOG41083MR nifu domain-containing protein ASL17_05065 ENOG4108YX9 iron--sulfur cluster insertion protein erpA ASL17_05075 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) ASL17_05085 ENOG4105KA0 thioesterase Superfamily protein ASL17_05140 ENOG41060GV RNA binding s1 domain protein ASL17_05145 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase ASL17_05150 ENOG4105C8Y Acetylornithine aminotransferase ASL17_05155 ENOG4105D82 Glutamate dehydrogenase ASL17_05165 ENOG4107VXM glycerophosphoryl diester phosphodiesterase ASL17_05195 ENOG4105C3F Signal peptidase i ASL17_05205 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation ASL17_05225 ENOG4108KP7 hydrolase ASL17_05235 ENOG4105EXC Acyl-transferase ASL17_05240 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit ASL17_05250 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) ASL17_05265 ENOG4105KIS phospholipid-binding protein ASL17_05290 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) ASL17_05300 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component ASL17_05305 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component ASL17_05315 ENOG4108JQ7 (ABC) transporter ASL17_05325 ENOG4105DEF Extracellular solute-binding protein, family 5 ASL17_05335 ENOG4108JQ7 (ABC) transporter ASL17_05345 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component ASL17_05350 ENOG4105C31 Tryptophanyl-tRNA synthetase ASL17_05355 ENOG41090SU Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity) ASL17_05370 ENOG4105DPN Oligoendopeptidase f ASL17_05375 ENOG4105T58 Dithiol-disulfide isomerase ASL17_05380 ENOG4108Z18 K06886 hemoglobin ASL17_05390 ENOG4106EFP UPF0738 protein ASL17_05405 ENOG4105EMS pseudouridine synthase ASL17_05410 ENOG4105CJW magnesium transporter ASL17_05425 ENOG4105C02 permease ASL17_05430 ENOG4105BZG amino acid carrier protein ASL17_05470 ENOG4107TS3 membrane protein, TerC ASL17_05475 ENOG4105C0H protease ASL17_05485 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic ASL17_05500 ENOG4105XVF Competence transcription factor ASL17_05545 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) ASL17_05570 ENOG4108HUF Transporter ASL17_05580 ENOG4105YB8 TM2 domain containing protein ASL17_05585 ENOG41080E2 ribosomal-protein-alanine acetyltransferase ASL17_05590 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase ASL17_05595 ENOG4105E4F Isochorismate synthase ASL17_05605 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) ASL17_05610 ENOG4108IPT Naphthoate synthase ASL17_05625 ENOG4108CHM Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases ASL17_05630 ENOG4105CHM Aminotransferase ASL17_05655 ENOG41082BV acetyltransferase ASL17_05665 ENOG4108KGH TRANSCRIPTIONal ASL17_05670 ENOG4105FQP Beta-lactamase ASL17_05710 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) ASL17_05715 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit ASL17_05725 ENOG4105VR9 phosphoribosylformylglycinamidine synthase ASL17_05740 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase ASL17_05750 ENOG4108V3E phosphoribosylglycinamide formyltransferase ASL17_05755 ENOG4105DC1 bifunctional purine biosynthesis protein purh ASL17_05760 ENOG4105C12 Phosphoribosylglycinamide synthetase ASL17_05765 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) ASL17_05770 ENOG4108JJB ABC transporter ASL17_05775 ENOG4105NSK ABC superfamily ATP binding cassette transporter membrane protein ASL17_05795 ENOG4105DR4 Methyltransferase ASL17_05805 ENOG4105KRI phosphocarrier protein (HPr ASL17_05810 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) ASL17_05830 ENOG4107ZYR domain protein ASL17_05855 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) ASL17_05865 ENOG4107RUY (E1 component), alpha subunit ASL17_05870 ENOG4105CPP Dehydrogenase, E1 component ASL17_05875 ENOG4105C7S Dehydrogenase ASL17_05880 ENOG4107QN2 dihydrolipoyl dehydrogenase ASL17_05900 ENOG4105F38 ABC transporter, permease ASL17_05905 ENOG4105D38 putrescine abc transporter ASL17_05910 ENOG4107RUE extracellular solute-binding protein family 1 ASL17_05935 ENOG4105ECY inositol monophosphatase ASL17_05945 ENOG4105CI3 gtp-binding protein typa ASL17_05965 ENOG4105CNI cell division protein FtsW ASL17_05970 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) ASL17_06020 ENOG4106H78 methyltransferase ASL17_06080 ENOG4105KFN sortase, SrtB family ASL17_06095 ENOG4108RWN rrna methyltransferase ASL17_06105 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) ASL17_06125 ENOG4105DCG PHP domain protein ASL17_06150 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit ASL17_06160 ENOG4105E33 succinate dehydrogenase ASL17_06170 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) ASL17_06240 ENOG4106UK0 Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity ASL17_06275 ENOG4105DBV ornithine carbamoyltransferase ASL17_06285 ENOG4105CSX c4-dicarboxylate anaerobic carrier ASL17_06345 ENOG41068DC Essential cell division protein (By similarity) ASL17_06350 ENOG4105CJN penicillin-binding protein ASL17_06365 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) ASL17_06370 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) ASL17_06375 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) ASL17_06380 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase ASL17_06385 ENOG4105DFA alanine racemase domain protein ASL17_06395 ENOG41067XK integral membrane protein ASL17_06415 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase ASL17_06430 ENOG4105C34 Pseudouridine synthase ASL17_06450 ENOG4105CD3 dihydroorotase ASL17_06455 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain ASL17_06470 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) ASL17_06485 ENOG4105F23 Fibronectin-binding protein ASL17_06500 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase ASL17_06505 ENOG4105C25 Primosomal protein n' ASL17_06515 ENOG4105YB8 TM2 domain containing protein ASL17_06520 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) ASL17_06530 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B ASL17_06540 ENOG4108ZF3 Phosphatase ASL17_06550 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) ASL17_06555 ENOG4105DJV ribulose-phosphate 3-epimerase ASL17_06570 ENOG4108ZAA Alkaline-shock protein ASL17_06580 ENOG4105CB5 ATP-dependent DNA helicase recG ASL17_06595 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase ASL17_06600 ENOG4105CHR reductase ASL17_06620 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) ASL17_06625 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ASL17_06670 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) ASL17_06685 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha ASL17_06690 ENOG41068KG domain protein ASL17_06700 ENOG4105C79 DNA protecting protein DprA ASL17_06765 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) ASL17_06770 ENOG4105KNE Phosphatidate cytidylyltransferase ASL17_06775 ENOG4105DZP Membrane-associated zinc metalloprotease ASL17_06785 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) ASL17_06795 ENOG4105CHV Transcription elongation factor NusA ASL17_06800 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination ASL17_06825 ENOG4105DTN riboflavin biosynthesis protein ribF ASL17_06845 ENOG4105CNU cell division protein FtsK ASL17_06850 ENOG4105FDP GntR family transcriptional regulator ASL17_06865 ENOG4108RKS Short-chain dehydrogenase reductase Sdr ASL17_06880 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase ASL17_06885 ENOG4105CEV competence damage-inducible protein ASL17_06905 ENOG4105D48 metallophosphoesterase ASL17_06910 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein ASL17_06915 ENOG4105DQU oxidoreductase, subunit beta ASL17_06950 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator ASL17_06955 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) ASL17_06980 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) ASL17_06985 ENOG4108V06 Glutathione peroxidase ASL17_06990 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) ASL17_06995 ENOG4105CXI aluminum resistance protein ASL17_07000 ENOG4105KV4 Transcriptional regulator ASL17_07005 ENOG4105C5F glutamine synthetase ASL17_07085 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) ASL17_07090 ENOG4108M15 ABC transporter ASL17_07105 ENOG4108S01 response regulator ASL17_07130 ENOG4105CFH Aspartokinase ASL17_07135 ENOG4105D6E homoserine dehydrogenase ASL17_07140 ENOG4108IYI Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) ASL17_07165 ENOG4108IQI permease ASL17_07195 ENOG4105K4I Scp-like extracellular ASL17_07215 ENOG4105CV1 Transketolase (EC 2.2.1.1) ASL17_07240 ENOG4105EYH Exonuclease ASL17_07250 ENOG4105C94 Transporter ASL17_07255 ENOG4108I0Z Aconitate hydratase ASL17_07275 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ASL17_07280 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ASL17_07315 ENOG4105FF5 Membrane ASL17_07320 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) ASL17_07325 ENOG4108RCF TRANSCRIPTIONal ASL17_07335 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) ASL17_07345 ENOG4105DER m42 family ASL17_07350 ENOG4105CRQ synthase (Component I) ASL17_07355 ENOG4105DDQ anthranilate synthase ASL17_07385 ENOG4108RMH femAB family ASL17_07390 ENOG4108TV1 Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity) ASL17_07395 ENOG4108KP7 hydrolase ASL17_07440 ENOG4105DPN Oligoendopeptidase f ASL17_07445 ENOG4108UTW Plays a role in the regulation of phosphate uptake ASL17_07455 ENOG4105E2Z phosphate ABC transporter (Permease ASL17_07460 ENOG4105C8U phosphate abc transporter ASL17_07480 ENOG4105C5H ABC transporter ASL17_07485 ENOG4105CFH Aspartokinase ASL17_07490 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) ASL17_07515 ENOG4108XFP Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) ASL17_07520 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) ASL17_07575 ENOG4107T89 von Willebrand factor, type A ASL17_07625 ENOG4108RS6 transposase ASL17_07630 ENOG410841Q phosphoesterase PA-phosphatase related protein ASL17_07635 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) ASL17_07645 ENOG4105CN1 protease ASL17_07660 ENOG4105C5Y PTS System ASL17_07670 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) ASL17_07680 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) ASL17_07695 ENOG4106QQ5 PBS lyase HEAT domain protein repeat-containing protein ASL17_07730 ENOG41063K0 cell wall associated fibronectin-binding protein ASL17_07740 ENOG4107R7I amino acid ASL17_07760 ENOG410890F Dynamin family ASL17_07780 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) ASL17_07815 ENOG4105BZ4 penicillin-binding protein ASL17_07825 ENOG4105CSM endonuclease III ASL17_07850 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate ASL17_07855 ENOG4105CPK Glycosyl transferase (Group 1 ASL17_07860 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase ASL17_07910 ENOG4105EAH synthase ASL17_07930 ENOG4105K70 DNA-binding protein ASL17_07945 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) ASL17_07970 ENOG4105HDK L-asparaginase ASL17_07975 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase ASL17_07990 ENOG4105C9U ATP-dependent DNA helicase RecQ ASL17_08045 ENOG4105BZU Histidine kinase ASL17_08050 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ASL17_08055 ENOG4105FE9 pseudouridine synthase ASL17_08075 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) ASL17_08080 ENOG4105I3K Ferric uptake regulator, Fur family ASL17_08085 ENOG4108YZ4 nudix hydrolase ASL17_08090 ENOG4105CPC Aldo Keto reductase ASL17_08100 ENOG4105PDP Short chain dehydrogenase ASL17_08105 ENOG4105II7 pyrroline-5-carboxylate reductase ASL17_08115 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase ASL17_08145 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) ASL17_08150 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) ASL17_08160 ENOG4108QEG Membrane ASL17_08170 ENOG4105C7S Dehydrogenase ASL17_08175 ENOG4105CPP Dehydrogenase, E1 component ASL17_08190 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) ASL17_08220 ENOG4108ZSR alkaline shock protein ASL17_08225 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase ASL17_08240 ENOG4105DC7 peptidase M24 ASL17_08255 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) ASL17_08260 ENOG4105WZW rhodanese family ASL17_08280 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) ASL17_08305 ENOG4106855 Competence protein ASL17_08310 ENOG4105D7Q type ii secretion system ASL17_08320 ENOG4105C5X domain protein ASL17_08345 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase ASL17_08355 ENOG4107RF6 penicillin-binding protein ASL17_08365 ENOG4105N80 Ferric uptake regulator, Fur family ASL17_08370 ENOG4105FAV ABC, transporter ASL17_08375 ENOG4105FDK ABC transporter ASL17_08385 ENOG4105C1J atp-dependent rna helicase ASL17_08390 ENOG4105EGD dinuclear metal center protein, YbgI family ASL17_08400 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ASL17_08405 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) ASL17_08435 ENOG4105KG3 cytidine deaminase ASL17_08450 ENOG4105C9A Phoh family ASL17_08465 ENOG4105F7J membrane-bound serine protease ASL17_08475 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) ASL17_08480 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) ASL17_08510 ENOG4105CSA Coproporphyrinogen iii oxidase ASL17_08530 ENOG4105TQK DNA polymerase iii, delta' subunit ASL17_08535 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 ASL17_08540 ENOG4108UK2 deaminase ASL17_08550 ENOG4105DXX methyltransferase ASL17_08555 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) ASL17_08560 ENOG4108WF2 Metal Dependent Phosphohydrolase ASL17_08570 ENOG410812S Rna-binding protein ASL17_08580 ENOG4105CQW ribosome biogenesis GTPase YqeH ASL17_08585 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase ASL17_08620 ENOG4105C5A transporter ASL17_08635 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein ASL17_08645 ENOG4105P4J Allophanate hydrolase, subunit 1 ASL17_08660 ENOG4105CFP Peptidase U32 ASL17_08665 ENOG4105XYU peptidase (U32 family) ASL17_08695 ENOG4105C7H Helicase, RecD TraA family ASL17_08710 ENOG4105C3J Cysteine desulfurase ASL17_08715 ENOG4105DEN Luciferase family ASL17_08735 ENOG4105D1H recombination factor protein RarA ASL17_08740 ENOG4105CUZ uba thif-type nad fad binding protein ASL17_08785 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) ASL17_08790 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) ASL17_08795 ENOG4105VIE preprotein translocase, subunit YajC ASL17_08835 ENOG4105X36 (ribosomal) protein ASL17_08875 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) ASL17_08880 ENOG41071EZ rRNA adenine N-6-methyltransferase ASL17_08885 ENOG4106JUT Streptomycin 3''-adenylyltransferase ASL17_08890 ENOG4105ZX1 Transposase C ASL17_08895 ENOG4108KU9 integrase family ASL17_08905 ENOG4108FPN Integrase ASL17_08915 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) ASL17_08925 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase ASL17_08935 ENOG4108R3E Dna-3-methyladenine glycosylase i ASL17_08955 ENOG4105D52 delta-aminolevulinic acid dehydratase ASL17_09005 ENOG4105U6W MutT NUDIX family protein ASL17_09030 ENOG4108IQI permease ASL17_09060 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase ASL17_09070 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) ASL17_09075 ENOG4105C2M dna polymerase I ASL17_09085 ENOG4105BZU Histidine kinase ASL17_09090 ENOG4105DPZ Two component transcriptional regulator (Winged helix family ASL17_09100 ENOG4108HMX isocitrate dehydrogenase (NADP) ASL17_09105 ENOG4105BZN citrate synthase ASL17_09110 ENOG4105C85 amino acid ASL17_09145 ENOG4105C6K Malic enzyme ASL17_09155 ENOG4105SFS phosphoesterase RecJ domain protein ASL17_09205 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) ASL17_09250 ENOG4108QXE glycerophosphoryl diester phosphodiesterase ASL17_09255 ENOG4108X3M OsmC Ohr family protein ASL17_09260 ENOG4105C5R Aminotransferase ASL17_09265 ENOG4108JQ1 Dehydrogenase ASL17_09285 ENOG4105F6E Acyl-transferase ASL17_09290 ENOG4105C0H protease ASL17_09330 ENOG4105F1V Acetoin utilization protein ASL17_09335 ENOG4105DGU Histone deacetylase ASL17_09340 ENOG4105ETE Transcriptional regulator (LacI family ASL17_09350 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase ASL17_09380 ENOG4108VDD TRNA binding domain protein ASL17_09405 ENOG4105C8F Beta-lactamase domain protein ASL17_09415 ENOG4108V15 phosphotransferase enzyme family ASL17_09420 ENOG4105F0I Aminotransferase ASL17_09445 ENOG4105CBX hi0933 family ASL17_09465 ENOG410605W Major Facilitator ASL17_09470 ENOG4105N5T Radical SAM Protein ASL17_09495 ENOG4105E8V Alpha Beta Hydrolase Fold protein ASL17_09515 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) ASL17_09520 ENOG4108R6K riboflavin synthase, subunit alpha ASL17_09525 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) ASL17_09540 ENOG4107R3E Citrate transporter ASL17_09550 ENOG4108FQ0 the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis ASL17_09580 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) ASL17_09590 ENOG4106A8V Protein CrcB homolog ASL17_09595 ENOG4106A8V Protein CrcB homolog ASL17_09610 ENOG4105CV8 reductase ASL17_09630 ENOG4108RS6 transposase ASL17_09750 ENOG4108CHM Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases ASL17_09800 ENOG4105DA5 (ABC) transporter ASL17_09905 ENOG4105C1Q protoporphyrinogen oxidase ASL17_09940 ENOG4105K59 histidine triad (HIT) protein ASL17_09970 ENOG4107VRP DNA repair exonuclease ASL17_09995 ENOG4105WH1 Two component transcriptional regulator luxr family ASL17_10000 ENOG4105BZU Histidine kinase ASL17_10005 ENOG4105C34 Pseudouridine synthase ASL17_10010 ENOG4105C9Q fumarate hydratase class II ASL17_10040 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) ASL17_10045 ENOG4105CDA abc transporter atp-binding protein ASL17_10050 ENOG4105E5Q amino acid AbC transporter ASL17_10225 ENOG4108M3J Dehydrogenase ASL17_10230 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen ASL17_10240 ENOG4107NBY Membrane ASL17_10265 ENOG41067AE Membrane-bound metal-dependent hydrolase ASL17_10280 ENOG4105EY8 ABC transporter ASL17_10325 ENOG4105ZMJ n-acetylmuramoyl-l-alanine amidase ASL17_10345 ENOG4108FQ0 the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis ASL17_10630 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) ASL17_10640 ENOG4108S4H thioesterase Superfamily protein ASL17_10665 ENOG4107U9T Pfam:Ribonuclease_BN ASL17_10670 ENOG4105WH1 Two component transcriptional regulator luxr family ASL17_10675 ENOG4105ENE Histidine kinase ASL17_10740 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) ASL17_10750 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) ASL17_10795 ENOG4105C4R Atp-dependent dna helicase ASL17_10800 ENOG4108RTE 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity) ASL17_10805 ENOG4105KGF protein, YerC YecD ASL17_10815 ENOG4107DDB Cysteine protease able to ASL17_10840 ENOG4105DAP Nicotinate phosphoribosyltransferase ASL17_10845 ENOG4107QN4 Catalyzes the production of nitric oxide (By similarity) ASL17_10850 ENOG4105CQC Prephenate dehydratase ASL17_10860 ENOG4105C8P )-transporter ASL17_10885 ENOG4105C26 Dehydrogenase ASL17_10935 ENOG4105CJ1 ABC, transporter ASL17_10950 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family ASL17_10980 ENOG4108QYW Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity) ASL17_11005 ENOG4105ZMJ n-acetylmuramoyl-l-alanine amidase ASL17_11010 ENOG4106Z3D Potent plasminogen activator that converts plasminogen into plasmin. It forms a 1 1 complex with plasmin, which in turn activates other plasminogen molecules ASL17_11015 ENOG4105ZMJ n-acetylmuramoyl-l-alanine amidase ASL17_11060 ENOG4105DR5 peptidase ASL17_11105 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) ASL17_11295 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) ASL17_11325 ENOG4108QYW Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity) ASL17_11355 ENOG4105CZN Potassium uptake protein ASL17_11370 ENOG4108TFU terminase (Small subunit) ASL17_11410 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase ASL17_11435 ENOG4108WCX response regulator ASL17_11460 ENOG4105BZU Histidine kinase ASL17_11515 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) ASL17_11525 ENOG4107S45 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) ASL17_11535 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) ASL17_11570 ENOG4105DVF Cytosine-specific methyltransferase ASL17_11575 ENOG410812X Methyltransferase ASL17_11635 ENOG4106J9J DNA polymerase ASL17_11640 ENOG4106J9J DNA polymerase ASL17_11670 ENOG4105KEG ribosomal-protein-alanine acetyltransferase ASL17_11690 ENOG4105D29 Helix-turn-helix type 11 domain protein ASL17_11765 ENOG4105MEW serine threonine protein phosphatase ASL17_11910 ENOG41088HM ASL17_12020 ENOG4105C7H Helicase, RecD TraA family ASL17_12175 ENOG4105ZMJ n-acetylmuramoyl-l-alanine amidase ASL17_12195 ENOG4105CUC YeeE YedE family protein ASL17_12205 ENOG4105C5H ABC transporter ASL17_12215 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) ASL17_12225 ENOG410801F ribosomal-protein-alanine acetyltransferase ASL17_12230 ENOG41072GX Peptidase M22 Glycoprotease ASL17_12235 ENOG4105K8N protein family UPF0079, ATPase ASL17_12250 ENOG4105C7K acetolactate synthase ASL17_12340 ENOG4105WN5 stage II sporulation protein ASL17_12345 ENOG4107SGM protein serine threonine phosphatase ASL17_12365 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) ASL17_12380 ENOG4105CKV Membrane ASL17_12390 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) ASL17_12395 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) ASL17_12410 ENOG4105C08 Histidine kinase ASL17_12415 ENOG4105EEX Two component transcriptional regulator (Winged helix family ASL17_12425 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) ASL17_12450 ENOG4105VPX protein, conserved in bacteria ASL17_12455 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) ASL17_12490 ENOG4105DWF phosphomethylpyrimidine kinase ASL17_12520 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) ASL17_12580 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase ASL17_12605 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) ASL17_12610 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) ASL17_12630 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) ASL17_12650 ENOG4105D2N Aldolase ASL17_12720 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) ASL17_12725 ENOG4105D3A purine nucleoside phosphorylase DeoD-type ASL17_12730 ENOG4108RMU ferritin dps family protein ASL17_12750 ENOG4105DG6 mannose-6-phosphate isomerase ASL17_12765 ENOG4105PGM cation diffusion facilitator family transporter ASL17_12800 ENOG4105DKW ABC transporter ASL17_12805 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) ASL17_12810 ENOG4105CTS PTS system mannitol-specific ASL17_12815 ENOG4105ETD TRANSCRIPTIONal ASL17_12820 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein ASL17_12845 ENOG4105C8B TIGR00159 family ASL17_12850 ENOG4105CYW agmatinase ASL17_12915 ENOG4105D1F ATP-binding protein ASL17_12935 ENOG4108UT2 hemolysin iii ASL17_12945 ENOG4107K5X Membrane-bound metal-dependent hydrolase ASL17_12955 ENOG4105DWD nucleoside recognition domain protein ASL17_12960 ENOG4108U1V ABC transporter, permease ASL17_12965 ENOG4105DQ5 transport system permease protein ASL17_12970 ENOG4108HUF Transporter ASL17_12980 ENOG4106M28 alanine racemase domain protein ASL17_12990 ENOG4107SFI Major Facilitator superfamily ASL17_13030 ENOG4105C94 Transporter ASL17_13035 ENOG4105CIS alcohol dehydrogenase ASL17_13040 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein ASL17_13055 ENOG4105CK1 PTS System ASL17_13060 ENOG4105VCP PTS System ASL17_13085 ENOG4105E98 transcriptional regulator DeoR family ASL17_13090 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) ASL17_13115 ENOG4105VUF Transcriptional regulator ASL17_13125 ENOG4106AM8 polysaccharide lyase family 8 ASL17_13145 ENOG4107FQX Alpha-acetolactate decarboxylase ASL17_13170 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit ASL17_13255 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) ASL17_13260 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) ASL17_13375 ENOG4105C7N Xanthine uracil vitamin C permease ASL17_13395 ENOG4105CSC Glucose uptake protein ASL17_13485 ENOG4108ZAF Molybdopterin ASL17_13490 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein ASL17_13495 ENOG4105CVM Molybdenum cofactor synthesis domain protein ASL17_13505 ENOG4105EPU Molybdenum cofactor synthesis domain protein ASL17_13510 ENOG4105D06 uba thif-type nad fad binding protein ASL17_13515 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) ASL17_13520 ENOG4105E0C molybdate abc transporter ASL17_13525 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein ASL17_13540 ENOG4107ZYJ bioY protein ASL17_13555 ENOG4105FDT acyl-CoA dehydrogenase ASL17_13625 ENOG41068JE domain protein ASL17_13635 ENOG4105DFD Na H antiporter ASL17_13670 ENOG4108FQ0 the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis ASL17_13745 ENOG4107YBY Hydrolase ASL17_13750 ENOG4105C09 Bile acid ASL17_13760 ENOG4105CI1 PTS System ASL17_13765 ENOG4108Q3X Transcriptional regulator ASL17_13785 ENOG4105CYX Short-chain dehydrogenase reductase Sdr ASL17_13790 ENOG4105CH2 amidohydrolase ASL17_13800 ENOG4105CGP Urocanate hydratase ASL17_13805 ENOG4105C5Q Transcriptional regulator ASL17_13825 ENOG4105E66 phosphoriboisomerase A ASL17_13830 ENOG4108RPX mosc domain containing protein ASL17_13850 ENOG4105RHA ABC transporter, permease ASL17_13855 ENOG4108IUX (ABC) transporter ASL17_13860 ENOG4105KAF membrAne ASL17_13870 ENOG4105D6U Sodium Glutamate Symporter ASL17_13880 ENOG4105D7N magnesium and cobalt transport protein CorA ASL17_13905 ENOG4105C0R drug resistance transporter emrb qaca subfamily ASL17_13910 ENOG4105CW7 secretion protein, HlyD family ASL17_13940 ENOG41062A4 Transcriptional regulator ASL17_13985 ENOG4105DWT malate dehydrogenase (quinone) ASL17_14015 ENOG4105KEG ribosomal-protein-alanine acetyltransferase ASL17_14040 ENOG4105ECB domain protein ASL17_14070 ENOG410606W general stress protein ASL17_14110 ENOG4107TXC Transcriptional regulator ASL17_14140 ENOG4108IUE nitrate reductase beta subunit ASL17_14150 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) ASL17_14155 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit ASL17_14160 ENOG4108IFG nitrite reductase, (NAD(P)H) ASL17_14170 ENOG4108XSB acetyltransferase, (GNAT) family ASL17_14175 ENOG4105TMB Formate nitrite transporter ASL17_14190 ENOG4105DSE periplasmic solute binding protein ASL17_14225 ENOG4105CDA abc transporter atp-binding protein ASL17_14230 ENOG4105DRP amino acid AbC transporter ASL17_14235 ENOG4105EAB amino acid AbC transporter ASL17_14290 ENOG4106XHW Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity) ASL17_14305 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) ASL17_14315 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) ASL17_14320 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) ASL17_14335 ENOG4105BZ1 (ABC) transporter ASL17_14360 ENOG4105BZW Glycerate kinase ASL17_14370 ENOG4105C2C drug resistance transporter, Bcr CflA ASL17_14395 ENOG4105EEQ Na H antiporter ASL17_14405 ENOG4105C0X amino acid ASL17_14415 ENOG4105ED2 Beta-lactamase ASL17_14430 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) ASL17_14435 ENOG4105C57 major facilitator superfamily ASL17_14440 ENOG4105R40 Glycine betaine carnitine choline ASL17_14450 ENOG4105E90 ABC transporter ASL17_14470 ENOG4105CZ9 Domain of unknown function (DU1801) ASL17_14475 ENOG4107QTZ amino acid ASL17_14480 ENOG4105EBR Carboxylesterase ASL17_14485 ENOG4105F27 Major Facilitator ASL17_14490 ENOG4105C4B ABC transporter, permease ASL17_14495 ENOG41083J0 (ABC) transporter ASL17_14500 ENOG4105CN9 Peptidase m42 family protein ASL17_14520 ENOG4105PQ4 (LipO)protein ASL17_14525 ENOG4105CBC glutamate synthase ASL17_14540 ENOG4108S9F abc transporter, atp-binding protein ASL17_14545 ENOG4108RZA ABC transporter ASL17_14550 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component ASL17_14555 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component ASL17_14560 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein ASL17_14590 ENOG4105CFC Transporter ASL17_14595 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) ASL17_14645 ENOG4105M6F mutator MutT protein ASL17_14720 ENOG4105CMG Carbohydrate kinase ASL17_14725 ENOG4105G3Z GntR family transcriptional regulator ASL17_14740 ENOG4105NRR Uncharacterized protein conserved in bacteria (DUF2188) ASL17_14750 ENOG4105DJB Major Facilitator Superfamily ASL17_14755 ENOG4107T5V SNARE associated Golgi ASL17_14775 ENOG4105CJ1 ABC, transporter ASL17_14795 ENOG4108K88 Membrane ASL17_14800 ENOG4105FBA Phospholipase Carboxylesterase ASL17_14810 ENOG41090MY MarR family Transcriptional regulator ASL17_14820 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase ASL17_14830 ENOG4105C5I Dehydrogenase ASL17_14835 ENOG4108AZI Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity) ASL17_14840 ENOG4108Z15 abc transporter atp-binding protein ASL17_14845 ENOG4106KKU ASL17_14850 ENOG4108Z6X (sortase) family ASL17_14855 ENOG4108Z7F N-acetyltransferase ASL17_14870 ENOG4105EJQ L-serine dehydratase ASL17_14890 ENOG4108UZ3 Transporter ASL17_14920 ENOG41067MG lrgb family ASL17_14930 ENOG4105CMU LysR family (Transcriptional regulator ASL17_14940 ENOG41068JE domain protein ASL17_14965 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase ASL17_14970 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) ASL17_14985 ENOG4105CE1 Ferrous iron transport protein b ASL17_14995 ENOG4105EYF MMPL domain protein ASL17_15050 ENOG4105FE1 phytoene synthase ASL17_15130 ENOG4105CHR reductase ASL17_15155 ENOG4107T5J pyridine nucleotide-disulfide oxidoreductase ASL17_15160 ENOG4105F9F transposase ASL17_15220 ENOG4106BHR ftsk SpoIIIE family protein ASL17_15245 ENOG4106128 DNA-binding helix-turn-helix protein ASL17_15280 ENOG4105FGM Fructosamine kinase ASL17_15285 ENOG4107QYT Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity) ASL17_15340 ENOG4107FQX Alpha-acetolactate decarboxylase ASL17_15355 ENOG4105CUB amino acid ASL17_15360 ENOG4108JPW Aminotransferase ASL17_15375 ENOG4105DWT malate dehydrogenase (quinone) ASL17_15385 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) ASL17_15405 ENOG4105C26 Dehydrogenase ASL17_15415 ENOG4105TRT Transcriptional regulator ASL17_15420 ENOG4105C94 Transporter ASL17_15435 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) ASL17_15440 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase ASL17_15445 ENOG4105D4T Citrate transporter ASL17_15455 ENOG4108Z73 Siroheme synthase ASL17_15460 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) ASL17_15520 ENOG4105G6Z alkaline phosphatase ASL17_15525 ENOG4108U05 Transcriptional regulator ASL17_15570 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) ASL17_15595 ENOG4105DM4 PTS System ASL17_15600 ENOG4105DG6 mannose-6-phosphate isomerase ASL17_15610 ENOG4108S4A n-acetylmuramoyl-l-alanine amidase ASL17_15615 ENOG4105WQI isochorismatase ASL17_15640 ENOG4106E62 Accessory Sec system protein Asp3 ASL17_15645 ENOG41089G2 accessory Sec system protein Asp2 ASL17_15650 ENOG4108XJK accessory Sec system protein Asp1 ASL17_15655 ENOG4106YAG Part of the accessory SecA2 SecY2 system specifically required for export of ASL17_15665 ENOG4107XWI flavin reductase domain protein, FMN-binding ASL17_15690 ENOG4107XC4 flavin reductase domain protein, FMN-binding ASL17_15695 ENOG4108F19 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) ASL17_15720 ENOG4108IG5 Transcriptional regulator ASL17_15725 ENOG4107QJZ Glycosyl transferase, family 2 ASL17_15755 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase ASL17_15780 ENOG4105CIH Imidazole acetol-phosphate transaminase ASL17_15860 ENOG4107QPK )-transporter ASL17_15865 ENOG4105FR1 rard protein ASL17_15875 ENOG4105D9G High-affinity ASL17_15890 ENOG4105C19 ABC transporter ASL17_15945 ENOG4108RS6 transposase ASL17_15950 ENOG410636K Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity) ASL17_15985 ENOG41081XE plasmid maintenance system antidote protein, xre family