locus-tag	class	description
EQW00_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
EQW00_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
EQW00_00015	ENOG410848D	S4 domain protein YaaA
EQW00_00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
EQW00_00025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EQW00_00030	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EQW00_00035	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
EQW00_00040	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
EQW00_00045	ENOG4108QYW	Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity)
EQW00_00060	ENOG4105DWV	Homoserine O-trans-acetylase
EQW00_00070	ENOG4105BZR	domain protein
EQW00_00075	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
EQW00_00080	ENOG4105CDU	Replicative dna helicase
EQW00_00085	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
EQW00_00105	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EQW00_00110	ENOG4105BZU	Histidine kinase
EQW00_00125	ENOG4105Q2H	domain protein
EQW00_00130	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
EQW00_00240	ENOG4105DZR	Type I site-specific deoxyribonuclease
EQW00_00245	ENOG4105EKX	Restriction modification system DNA (Specificity
EQW00_00250	ENOG4105CVR	type I restriction-modification system
EQW00_00270	ENOG4105DUY	Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein
EQW00_00275	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
EQW00_00345	ENOG4105DZR	Type I site-specific deoxyribonuclease
EQW00_00360	ENOG4108HK0	-acetyltransferase
EQW00_00395	ENOG4107Y5K	Resolvase
EQW00_00420	ENOG4105KTU	Transcriptional regulator, arsr family
EQW00_00430	ENOG4105C59	p-type ATPase
EQW00_00460	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
EQW00_00530	ENOG4105UD4	alkylmercury lyase
EQW00_00570	ENOG4105DQ6	Transposase
EQW00_00575	ENOG4105C5B	carbamate kinase
EQW00_00580	ENOG4105DBV	ornithine carbamoyltransferase
EQW00_00585	ENOG4105IJS	Transcriptional regulator
EQW00_00595	ENOG4105CEU	Arginine dihydrolase
EQW00_00600	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
EQW00_00635	ENOG4106QP9	(LipO)protein
EQW00_00645	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EQW00_00655	ENOG4105DA5	(ABC) transporter
EQW00_00670	ENOG4108WZ2	response regulator
EQW00_00675	ENOG4105BZU	Histidine kinase
EQW00_00700	ENOG4105C59	p-type ATPase
EQW00_00705	ENOG4107STQ	Multicopper oxidase
EQW00_00710	ENOG41090UD	(LipO)protein
EQW00_00715	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
EQW00_00720	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
EQW00_00725	ENOG4105XTG	Pfam:DUF156
EQW00_00730	ENOG41087NI	Sulfite exporter TauE/SafE
EQW00_00735	ENOG4108UXE	Protein tyrosine phosphatase
EQW00_00740	ENOG4107R5R	arsenical pump membrane protein
EQW00_00760	ENOG41085FC	arsR family transcriptional regulator
EQW00_00765	ENOG4108PJD	permease
EQW00_00775	ENOG4106QP9	(LipO)protein
EQW00_00780	ENOG4106QP9	(LipO)protein
EQW00_00785	ENOG4106QP9	(LipO)protein
EQW00_00790	ENOG4105D8X	mechanosensitive ion channel
EQW00_00795	ENOG4105TRI	Hydrolase
EQW00_00835	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
EQW00_00840	ENOG4105DWT	malate dehydrogenase (quinone)
EQW00_00855	ENOG4105CHR	reductase
EQW00_00865	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
EQW00_00870	ENOG4105CXY	transporter
EQW00_00875	ENOG4107VQW	regulatoR
EQW00_00880	ENOG4105C2F	Histidine kinase
EQW00_00920	ENOG4108M1Z	surface protein
EQW00_00935	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
EQW00_00940	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
EQW00_00945	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
EQW00_00950	ENOG4108W8G	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP (By similarity)
EQW00_00960	ENOG4107DDB	Cysteine protease able to
EQW00_00975	ENOG4105CKI	cobalamin synthesis protein
EQW00_00985	ENOG4107T5J	pyridine nucleotide-disulfide oxidoreductase
EQW00_01000	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
EQW00_01010	ENOG4105CHR	reductase
EQW00_01015	ENOG4108IJ6	ABC transporter
EQW00_01050	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EQW00_01060	ENOG4108RZA	ABC transporter
EQW00_01065	ENOG4108S9F	abc transporter, atp-binding protein
EQW00_01075	ENOG4105C6N	Formate acetyltransferase
EQW00_01080	ENOG4105F1A	Pyruvate formate-lyase
EQW00_01085	ENOG4107PP3	Acetylornithine deacetylase
EQW00_01090	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
EQW00_01095	ENOG4108RZE	Tetr family transcriptional regulator
EQW00_01105	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
EQW00_01140	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
EQW00_01145	ENOG4105C5B	carbamate kinase
EQW00_01150	ENOG4105DBV	ornithine carbamoyltransferase
EQW00_01160	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
EQW00_01165	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
EQW00_01170	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
EQW00_01180	ENOG4105CMT	Dihydroxyacetone kinase
EQW00_01185	ENOG4108UTZ	Dihydroxyacetone kinase
EQW00_01190	ENOG4105VDH	Dihydroxyacetone kinase
EQW00_01230	ENOG4105J1V	Triacylglycerol lipase
EQW00_01240	ENOG4107QNK	)-transporter
EQW00_01255	ENOG4105FR1	rard protein
EQW00_01260	ENOG4107Z6I	Thiamine biosynthesis protein
EQW00_01265	ENOG4107QPK	)-transporter
EQW00_01275	ENOG4107RUY	(E1 component), alpha subunit
EQW00_01285	ENOG4107QKR	Dehydrogenase
EQW00_01305	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
EQW00_01310	ENOG4105C72	UPF0176 protein
EQW00_01315	ENOG4108TY5	Exhibits lactonase activity. Acts in cells with perturbed membrane integrity and is possibly related to the membrane homeostasis
EQW00_01320	ENOG4108YYC	ycei family
EQW00_01330	ENOG4105DWT	malate dehydrogenase (quinone)
EQW00_01340	ENOG4105G7B	Protein of unknown function (DUF2992)
EQW00_01355	ENOG41071FY	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
EQW00_01360	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
EQW00_01365	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
EQW00_01370	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
EQW00_01375	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
EQW00_01380	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
EQW00_01385	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
EQW00_01390	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
EQW00_01395	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
EQW00_01405	ENOG4105J1V	Triacylglycerol lipase
EQW00_01425	ENOG4105F27	Major Facilitator
EQW00_01430	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
EQW00_01445	ENOG4105D5T	phosphonate abc transporter
EQW00_01465	ENOG4106432	Mediates binding to human platelets, possibly through a receptor-ligand interaction. Probably associated with virulence in endovascular infection (By similarity)
EQW00_01470	ENOG4106YAG	Part of the accessory SecA2 SecY2 system specifically required for export of
EQW00_01475	ENOG4108XJK	accessory Sec system protein Asp1
EQW00_01480	ENOG41089G2	accessory Sec system protein Asp2
EQW00_01490	ENOG4108MGR	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane (By similarity)
EQW00_01500	ENOG4105EDE	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1 (By similarity)
EQW00_01510	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
EQW00_01520	ENOG4105E5M	Multidrug resistance protein D
EQW00_01540	ENOG4108ZHJ	Organic hydroperoxide resistance protein
EQW00_01550	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
EQW00_01560	ENOG4105DG6	mannose-6-phosphate isomerase
EQW00_01565	ENOG4105DM4	PTS System
EQW00_01570	ENOG4105EMD	TRANSCRIPTIONal
EQW00_01580	ENOG4105CHR	reductase
EQW00_01605	ENOG4107PP3	Acetylornithine deacetylase
EQW00_01610	ENOG4105D4Y	metalloprotease
EQW00_01615	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
EQW00_01620	ENOG4105CEU	Arginine dihydrolase
EQW00_01625	ENOG4105DBV	ornithine carbamoyltransferase
EQW00_01635	ENOG4105IJS	Transcriptional regulator
EQW00_01645	ENOG4105PNM	synthesis protein
EQW00_01655	ENOG4107RA9	decarboxylase
EQW00_01665	ENOG4108RS6	transposase
EQW00_01695	ENOG4105K7W	phage-related replication protein
EQW00_01705	ENOG4107SJB	teichoic acid biosynthesis
EQW00_01710	ENOG4105CGD	Nad-dependent epimerase dehydratase
EQW00_01715	ENOG4105G6Z	alkaline phosphatase
EQW00_01730	ENOG4105EWM	Histidine kinase
EQW00_01750	ENOG4107RUZ	Sss sodium solute transporter superfamily
EQW00_01775	ENOG4105K56	Transcriptional regulator
EQW00_01780	ENOG4105DC8	reductase
EQW00_01795	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
EQW00_01800	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
EQW00_01805	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
EQW00_01810	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
EQW00_01815	ENOG4108Z73	Siroheme synthase
EQW00_01820	ENOG410635A	Membrane
EQW00_01825	ENOG4107RIQ	Sulfate adenylate transferase
EQW00_01830	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
EQW00_01840	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
EQW00_01845	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
EQW00_01850	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
EQW00_01860	ENOG4105C94	Transporter
EQW00_01865	ENOG4105TRT	Transcriptional regulator
EQW00_01870	ENOG4105C26	Dehydrogenase
EQW00_01875	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
EQW00_01895	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EQW00_01900	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
EQW00_01905	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
EQW00_01910	ENOG4105DWT	malate dehydrogenase (quinone)
EQW00_01920	ENOG4105WYW	fructose-bisphosphate aldolase
EQW00_01930	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
EQW00_01960	ENOG4108JPW	Aminotransferase
EQW00_01965	ENOG4105CUB	amino acid
EQW00_01970	ENOG4105CMU	LysR family (Transcriptional regulator
EQW00_01975	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
EQW00_01985	ENOG4107FQX	Alpha-acetolactate decarboxylase
EQW00_01995	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
EQW00_02000	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
EQW00_02005	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
EQW00_02030	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
EQW00_02035	ENOG4105FGM	Fructosamine kinase
EQW00_02040	ENOG4105C85	amino acid
EQW00_02050	ENOG4105CSR	polyphosphate kinase 2
EQW00_02060	ENOG4106770	Is able to cleave peptidoglycan (By similarity)
EQW00_02090	ENOG410681U	heavy metal transport detoxification protein
EQW00_02095	ENOG4105C59	p-type ATPase
EQW00_02105	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
EQW00_02110	ENOG4105C26	Dehydrogenase
EQW00_02135	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
EQW00_02140	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
EQW00_02160	ENOG4105DND	Transcriptional regulator
EQW00_02165	ENOG4105VAW	lrga family
EQW00_02170	ENOG41067MG	lrgb family
EQW00_02180	ENOG4105CI1	PTS System
EQW00_02195	ENOG4105E2A	Dehydrogenase
EQW00_02205	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
EQW00_02220	ENOG4105N98	Capsule biosynthesis protein capB
EQW00_02230	ENOG4105PNM	synthesis protein
EQW00_02245	ENOG4105EV1	Ribose uptake protein RbsU
EQW00_02250	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
EQW00_02260	ENOG4105CMG	Carbohydrate kinase
EQW00_02285	ENOG4105EJQ	L-serine dehydratase
EQW00_02295	ENOG4108Z7F	N-acetyltransferase
EQW00_02300	ENOG4108Z6X	(sortase) family
EQW00_02305	ENOG4108AZI	Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity)
EQW00_02310	ENOG4105C5I	Dehydrogenase
EQW00_02315	ENOG4108RCM	Nitroreductase
EQW00_02325	ENOG4105C26	Dehydrogenase
EQW00_02335	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
EQW00_02350	ENOG4105C26	Dehydrogenase
EQW00_02355	ENOG4108K88	Membrane
EQW00_02370	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
EQW00_02375	ENOG4107T5V	SNARE associated Golgi
EQW00_02380	ENOG4105D06	uba thif-type nad fad binding protein
EQW00_02385	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
EQW00_02395	ENOG41080HI	glycine oxidase
EQW00_02405	ENOG4105DJB	Major Facilitator Superfamily
EQW00_02420	ENOG4105NRR	Uncharacterized protein conserved in bacteria (DUF2188)
EQW00_02450	ENOG4105CXY	transporter
EQW00_02455	ENOG4105G3Z	GntR family transcriptional regulator
EQW00_02460	ENOG4105CMG	Carbohydrate kinase
EQW00_02465	ENOG4105C6Z	Gluconate
EQW00_02470	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
EQW00_02475	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
EQW00_02480	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
EQW00_02500	ENOG4105EMU	Dehydrogenase
EQW00_02510	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
EQW00_02520	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
EQW00_02530	ENOG4105CN9	Peptidase m42 family protein
EQW00_02540	ENOG4105CBC	glutamate synthase
EQW00_02560	ENOG41083J0	(ABC) transporter
EQW00_02565	ENOG4105C4B	ABC transporter, permease
EQW00_02570	ENOG4105F27	Major Facilitator
EQW00_02575	ENOG4105EBR	Carboxylesterase
EQW00_02580	ENOG4107QTZ	amino acid
EQW00_02610	ENOG4105R40	Glycine betaine carnitine choline
EQW00_02615	ENOG41067MG	lrgb family
EQW00_02620	ENOG4105Z9F	murein hydrolase regulator LrgA
EQW00_02625	ENOG4105DY9	regulatoR
EQW00_02630	ENOG4108HRK	Histidine kinase
EQW00_02635	ENOG4105C57	major facilitator superfamily
EQW00_02640	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
EQW00_02645	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EQW00_02655	ENOG4105C0X	amino acid
EQW00_02660	ENOG4105C85	amino acid
EQW00_02685	ENOG4105BZW	Glycerate kinase
EQW00_02705	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
EQW00_02715	ENOG4105EAB	amino acid AbC transporter
EQW00_02720	ENOG4105DRP	amino acid AbC transporter
EQW00_02725	ENOG4105CDA	abc transporter atp-binding protein
EQW00_02730	ENOG4108RMH	femAB family
EQW00_02750	ENOG4105TMB	Formate nitrite transporter
EQW00_02755	ENOG4108XSB	acetyltransferase, (GNAT) family
EQW00_02760	ENOG4107RRN	ABC transporter substrate-binding protein
EQW00_02775	ENOG4108IFG	nitrite reductase, (NAD(P)H)
EQW00_02780	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
EQW00_02785	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
EQW00_02795	ENOG4108IUE	nitrate reductase beta subunit
EQW00_02815	ENOG4105BZU	Histidine kinase
EQW00_02820	ENOG4105WH1	Two component transcriptional regulator luxr family
EQW00_02825	ENOG4105DQQ	Major facilitator superfamily MFS_1
EQW00_02830	ENOG4105K56	Transcriptional regulator
EQW00_02835	ENOG4108TVJ	Nitroreductase
EQW00_02855	ENOG410606W	general stress protein
EQW00_02910	ENOG41090PH	Protease synthase and sporulation negative regulatory protein pai 1
EQW00_02915	ENOG4107SJB	teichoic acid biosynthesis
EQW00_02925	ENOG4107SJB	teichoic acid biosynthesis
EQW00_02935	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
EQW00_02940	ENOG4105DWT	malate dehydrogenase (quinone)
EQW00_02945	ENOG4105BZU	Histidine kinase
EQW00_02950	ENOG4105EFI	regulatoR
EQW00_02955	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
EQW00_02960	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
EQW00_02970	ENOG41062A4	Transcriptional regulator
EQW00_02975	ENOG4105T65	Membrane-associated protein
EQW00_02980	ENOG4105C2C	drug resistance transporter, Bcr CflA
EQW00_02990	ENOG4105CW7	secretion protein, HlyD family
EQW00_02995	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
EQW00_03025	ENOG4105D7N	magnesium and cobalt transport protein CorA
EQW00_03030	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
EQW00_03035	ENOG4105D6U	Sodium Glutamate Symporter
EQW00_03055	ENOG4108VX5	3-methyladenine DNA glycosylase
EQW00_03080	ENOG4105EF1	ribulokinase
EQW00_03085	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
EQW00_03095	ENOG4105E66	phosphoriboisomerase A
EQW00_03110	ENOG4106E7R	Lysostaphin resistance protein A
EQW00_03115	ENOG41088SP	formiminoglutamate hydrolase
EQW00_03120	ENOG4105CH2	amidohydrolase
EQW00_03125	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
EQW00_03130	ENOG4107XC4	flavin reductase domain protein, FMN-binding
EQW00_03155	ENOG4108Q3X	Transcriptional regulator
EQW00_03160	ENOG4105CI1	PTS System
EQW00_03170	ENOG4107YBY	Hydrolase
EQW00_03205	ENOG4105C5Y	PTS System
EQW00_03210	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EQW00_03225	ENOG4108TYN	CAAX amino terminal protease family protein
EQW00_03230	ENOG4105D29	Helix-turn-helix type 11 domain protein
EQW00_03235	ENOG4105ECY	inositol monophosphatase
EQW00_03240	ENOG4108KGH	TRANSCRIPTIONal
EQW00_03260	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
EQW00_03270	ENOG4105C5I	Dehydrogenase
EQW00_03275	ENOG41080TC	multidrug resistance protein
EQW00_03280	ENOG4105KPY	Small multidrug resistance protein
EQW00_03300	ENOG4105DFD	Na H antiporter
EQW00_03330	ENOG4105ICD	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
EQW00_03335	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
EQW00_03340	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
EQW00_03345	ENOG4105HFU	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
EQW00_03350	ENOG4105CQM	Urea amidohydrolase subunit alpha
EQW00_03355	ENOG4105KI2	Urea amidohydrolase subunit beta
EQW00_03360	ENOG4108YZ9	Urea amidohydrolase subunit gamma
EQW00_03375	ENOG4105FDT	acyl-CoA dehydrogenase
EQW00_03380	ENOG4105DU0	nucleoside hydrolase
EQW00_03385	ENOG4107ZYJ	bioY protein
EQW00_03395	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
EQW00_03405	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
EQW00_03410	ENOG4105E0C	molybdate abc transporter
EQW00_03415	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
EQW00_03420	ENOG4105D06	uba thif-type nad fad binding protein
EQW00_03425	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
EQW00_03430	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EQW00_03435	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
EQW00_03445	ENOG4108ZAF	Molybdopterin
EQW00_03455	ENOG41082CS	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
EQW00_03460	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EQW00_03495	ENOG4108TV1	Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity)
EQW00_03520	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
EQW00_03525	ENOG4105CSC	Glucose uptake protein
EQW00_03530	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EQW00_03535	ENOG4105C7N	Xanthine uracil vitamin C permease
EQW00_03550	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
EQW00_03555	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
EQW00_03560	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
EQW00_03565	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EQW00_03570	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
EQW00_03575	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
EQW00_03580	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
EQW00_03585	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
EQW00_03595	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
EQW00_03600	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
EQW00_03605	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
EQW00_03610	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EQW00_03615	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
EQW00_03620	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
EQW00_03625	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
EQW00_03630	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
EQW00_03635	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
EQW00_03640	ENOG4105VPB	50S ribosomal protein L30
EQW00_03645	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
EQW00_03650	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
EQW00_03655	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
EQW00_03660	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
EQW00_03665	ENOG41067V7	50S ribosomal protein L36
EQW00_03670	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EQW00_03675	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
EQW00_03680	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EQW00_03685	ENOG4108ZT0	50S ribosomal protein l17
EQW00_03690	ENOG4108JJB	ABC transporter
EQW00_03695	ENOG4108JJB	ABC transporter
EQW00_03705	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
EQW00_03710	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
EQW00_03715	ENOG4108UJD	30S ribosomal protein S9
EQW00_03720	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
EQW00_03725	ENOG4105E98	transcriptional regulator DeoR family
EQW00_03730	ENOG4105RSI	Galactose-6-phosphate isomerase subunit LacA
EQW00_03740	ENOG4106VEM	tagatose-6-phosphate kinase
EQW00_03745	ENOG4105D2M	Aldolase
EQW00_03750	ENOG4105VCP	PTS System
EQW00_03755	ENOG4105CK1	PTS System
EQW00_03760	ENOG4105CS2	ec 3.2.1.21
EQW00_03770	ENOG4105DEN	Luciferase family
EQW00_03775	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
EQW00_03780	ENOG4105CIS	alcohol dehydrogenase
EQW00_03795	ENOG4105VBF	alkaline shock protein
EQW00_03800	ENOG4105DBM	Siderophore biosynthesis protein
EQW00_03805	ENOG4107SFI	Major Facilitator superfamily
EQW00_03815	ENOG4106M28	alanine racemase domain protein
EQW00_03820	ENOG4108HUF	Transporter
EQW00_03825	ENOG4105DQ5	transport system permease protein
EQW00_03830	ENOG4108U1V	ABC transporter, permease
EQW00_03835	ENOG4105DWD	nucleoside recognition domain protein
EQW00_03840	ENOG4106EQQ	Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity)
EQW00_03845	ENOG4107DUR	UPF0457 protein
EQW00_03850	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
EQW00_03855	ENOG4108MYC	UTP-glucose-1-phosphate uridylyltransferase
EQW00_03880	ENOG4105D1F	ATP-binding protein
EQW00_03930	ENOG4105C8B	TIGR00159 family
EQW00_03940	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
EQW00_03945	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
EQW00_03965	ENOG4105PGM	cation diffusion facilitator family transporter
EQW00_03985	ENOG4105DG6	mannose-6-phosphate isomerase
EQW00_04010	ENOG4108RMU	ferritin dps family protein
EQW00_04015	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
EQW00_04020	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
EQW00_04025	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
EQW00_04030	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
EQW00_04040	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
EQW00_04060	ENOG4105HNY	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
EQW00_04070	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
EQW00_04075	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
EQW00_04085	ENOG4105D2N	Aldolase
EQW00_04090	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
EQW00_04095	ENOG4105C26	Dehydrogenase
EQW00_04100	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
EQW00_04105	ENOG41082DI	50s ribosomal protein l31
EQW00_04115	ENOG4107104	thymidine kinase
EQW00_04120	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
EQW00_04125	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
EQW00_04135	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EQW00_04140	ENOG4107WAU	Protein tyrosine phosphatase
EQW00_04145	ENOG4108UIC	UPF0340 protein
EQW00_04150	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
EQW00_04155	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
EQW00_04160	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
EQW00_04170	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
EQW00_04180	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
EQW00_04190	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
EQW00_04195	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
EQW00_04200	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
EQW00_04205	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
EQW00_04215	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
EQW00_04220	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
EQW00_04240	ENOG4105JH5	thiaminase II
EQW00_04250	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
EQW00_04255	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
EQW00_04260	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
EQW00_04270	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
EQW00_04275	ENOG4105VPX	protein, conserved in bacteria
EQW00_04295	ENOG4105CPF	Cell wall formation (By similarity)
EQW00_04300	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
EQW00_04305	ENOG4105C1J	atp-dependent rna helicase
EQW00_04315	ENOG4105CKV	Membrane
EQW00_04320	ENOG410905X	membrane-flanked domain protein
EQW00_04325	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
EQW00_04330	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
EQW00_04340	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
EQW00_04345	ENOG4107SGM	protein serine threonine phosphatase
EQW00_04350	ENOG4105WN5	stage II sporulation protein
EQW00_04355	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
EQW00_04370	ENOG410906U	SprT-like
EQW00_04410	ENOG4105C7B	Threonine dehydratase
EQW00_04415	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EQW00_04420	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EQW00_04425	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EQW00_04430	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
EQW00_04435	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
EQW00_04445	ENOG4105C7K	acetolactate synthase
EQW00_04450	ENOG4105C01	Dihydroxy-acid dehydratase
EQW00_04455	ENOG4105K8N	protein family UPF0079, ATPase
EQW00_04460	ENOG41072GX	Peptidase M22 Glycoprotease
EQW00_04465	ENOG410801F	ribosomal-protein-alanine acetyltransferase
EQW00_04470	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EQW00_04475	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
EQW00_04480	ENOG4105C5H	ABC transporter
EQW00_04485	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
EQW00_04495	ENOG4105CUC	YeeE YedE family protein
EQW00_04505	ENOG4105BZU	Histidine kinase
EQW00_04530	ENOG4108WCX	response regulator
EQW00_04545	ENOG410695V	Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of AgrD, the precursor of AIP (By similarity)
EQW00_04555	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
EQW00_04570	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
EQW00_04575	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
EQW00_04595	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
EQW00_04600	ENOG4105DA5	(ABC) transporter
EQW00_04610	ENOG4105CJ1	ABC, transporter
EQW00_04655	ENOG4108FPN	Integrase
EQW00_04660	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EQW00_04700	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
EQW00_04705	ENOG4105C26	Dehydrogenase
EQW00_04710	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
EQW00_04725	ENOG4105CQC	Prephenate dehydratase
EQW00_04735	ENOG4105DAP	Nicotinate phosphoribosyltransferase
EQW00_04740	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
EQW00_04745	ENOG4108U5N	UPF0316 protein
EQW00_04755	ENOG4105C83	adenylosuccinate lyase
EQW00_04760	ENOG4105KGF	protein, YerC YecD
EQW00_04765	ENOG4108RTE	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity)
EQW00_04770	ENOG4105C4R	Atp-dependent dna helicase
EQW00_04775	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
EQW00_04785	ENOG4105CK7	Sodium proline symporter
EQW00_04790	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
EQW00_04795	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
EQW00_04800	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
EQW00_04805	ENOG4105CBD	Diacylglycerol kinase
EQW00_04810	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
EQW00_04820	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
EQW00_04830	ENOG41090A1	ferritin
EQW00_04850	ENOG4108V3A	UPF0421 protein
EQW00_04855	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
EQW00_04870	ENOG4105ENE	Histidine kinase
EQW00_04875	ENOG4105WH1	Two component transcriptional regulator luxr family
EQW00_04880	ENOG4107U9T	Pfam:Ribonuclease_BN
EQW00_04890	ENOG4107ZCW	Low molecular weight phosphotyrosine protein phosphatase
EQW00_04895	ENOG41068PA	UPF0435 protein
EQW00_04905	ENOG4108S4H	thioesterase Superfamily protein
EQW00_04925	ENOG4108Z0Z	intracellular protease Pfpi family
EQW00_04930	ENOG4105BZ4	penicillin-binding protein
EQW00_04935	ENOG410902V	Modulates RecA activity (By similarity)
EQW00_04945	ENOG4105EY8	ABC transporter
EQW00_04955	ENOG41067AE	Membrane-bound metal-dependent hydrolase
EQW00_04965	ENOG4105EVI	UPF0374 protein
EQW00_04975	ENOG4107NBY	Membrane
EQW00_04980	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
EQW00_04985	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EQW00_04990	ENOG4105C5I	Dehydrogenase
EQW00_04995	ENOG4105G5W	regulator Fur family
EQW00_05145	ENOG4108CHM	Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases
EQW00_05155	ENOG4105E5Q	amino acid AbC transporter
EQW00_05160	ENOG4105CDA	abc transporter atp-binding protein
EQW00_05165	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
EQW00_05190	ENOG4105C9Q	fumarate hydratase class II
EQW00_05195	ENOG4108YBP	pseudouridine synthase
EQW00_05200	ENOG4105BZU	Histidine kinase
EQW00_05205	ENOG4105WH1	Two component transcriptional regulator luxr family
EQW00_05215	ENOG4108UH6	UPF0754 membrane protein
EQW00_05220	ENOG4105WZB	UPF0342 protein
EQW00_05225	ENOG4107VRP	DNA repair exonuclease
EQW00_05235	ENOG4105EQI	Metal Dependent Phosphohydrolase
EQW00_05245	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
EQW00_05260	ENOG4105K59	histidine triad (HIT) protein
EQW00_05280	ENOG4105Q24	Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation
EQW00_05285	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
EQW00_05290	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
EQW00_05295	ENOG4105C1Q	protoporphyrinogen oxidase
EQW00_05395	ENOG4105CEY	Amp-dependent synthetase and ligase
EQW00_05405	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
EQW00_05420	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
EQW00_05425	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
EQW00_05445	ENOG4106A8V	Protein CrcB homolog
EQW00_05450	ENOG4106A8V	Protein CrcB homolog
EQW00_05460	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
EQW00_05490	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
EQW00_05500	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
EQW00_05505	ENOG4108R6K	riboflavin synthase, subunit alpha
EQW00_05510	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
EQW00_05515	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
EQW00_05525	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
EQW00_05540	ENOG4105N5T	Radical SAM Protein
EQW00_05545	ENOG410605W	Major Facilitator
EQW00_05550	ENOG4105C8T	Leucyl-tRNA synthetase
EQW00_05565	ENOG4105CBX	hi0933 family
EQW00_05585	ENOG4107QSE	Dipeptidase
EQW00_05590	ENOG4105F0I	Aminotransferase
EQW00_05595	ENOG4108V15	phosphotransferase enzyme family
EQW00_05600	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
EQW00_05620	ENOG4108NKM	UPF0354 protein
EQW00_05625	ENOG4108VDD	TRNA binding domain protein
EQW00_05635	ENOG4105DFU	Cell wall formation (By similarity)
EQW00_05640	ENOG4105MQN	general stress protein
EQW00_05650	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
EQW00_05655	ENOG4105ETE	Transcriptional regulator (LacI family
EQW00_05660	ENOG4105CKU	formyltetrahydrofolate synthetase
EQW00_05670	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
EQW00_05675	ENOG4105C0H	protease
EQW00_05680	ENOG4105F6E	Acyl-transferase
EQW00_05695	ENOG4108JQ1	Dehydrogenase
EQW00_05700	ENOG4105C5R	Aminotransferase
EQW00_05705	ENOG4108X3M	OsmC Ohr family protein
EQW00_05710	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
EQW00_05715	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
EQW00_05730	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
EQW00_05740	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
EQW00_05750	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
EQW00_05760	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
EQW00_05765	ENOG4107YZX	Universal stress protein
EQW00_05770	ENOG4105DCF	alanine dehydrogenase
EQW00_05775	ENOG4105DC7	peptidase M24
EQW00_05780	ENOG4105E8R	UPF0173 metal-dependent hydrolase
EQW00_05795	ENOG4105SFS	phosphoesterase RecJ domain protein
EQW00_05800	ENOG4105C0B	DNA polymerase III (alpha subunit)
EQW00_05805	ENOG4105C6K	Malic enzyme
EQW00_05810	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
EQW00_05815	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
EQW00_05820	ENOG4105CTQ	phosphohexokinase
EQW00_05825	ENOG4105CA9	Pyruvate kinase
EQW00_05830	ENOG4105C85	amino acid
EQW00_05835	ENOG4105BZN	citrate synthase
EQW00_05840	ENOG4108HMX	isocitrate dehydrogenase (NADP)
EQW00_05845	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
EQW00_05850	ENOG4105BZU	Histidine kinase
EQW00_05855	ENOG4105C2M	dna polymerase I
EQW00_05860	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
EQW00_05865	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
EQW00_05875	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
EQW00_05885	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
EQW00_05900	ENOG4105C22	threonyL-tRNA synthetase
EQW00_05905	ENOG4108IQI	permease
EQW00_05910	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
EQW00_05915	ENOG4105VJV	50s ribosomal protein L35
EQW00_05920	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
EQW00_05925	ENOG4105U6W	MutT NUDIX family protein
EQW00_05935	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
EQW00_05940	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
EQW00_05945	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
EQW00_05950	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
EQW00_05960	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
EQW00_05970	ENOG4105D52	delta-aminolevulinic acid dehydratase
EQW00_05975	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
EQW00_05985	ENOG4108R3E	Dna-3-methyladenine glycosylase i
EQW00_05990	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
EQW00_05995	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
EQW00_06005	ENOG4105W5Q	DNA repair protein (RadC
EQW00_06025	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
EQW00_06035	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
EQW00_06040	ENOG4105X36	(ribosomal) protein
EQW00_06045	ENOG4105K46	50S ribosomal protein l27
EQW00_06050	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EQW00_06055	ENOG41090I5	UPF0735 ACT domain-containing protein
EQW00_06060	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
EQW00_06065	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
EQW00_06070	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
EQW00_06075	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
EQW00_06080	ENOG4105VIE	preprotein translocase, subunit YajC
EQW00_06085	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
EQW00_06090	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
EQW00_06095	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
EQW00_06105	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
EQW00_06110	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
EQW00_06115	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
EQW00_06120	ENOG4105CUT	histidyl-tRNA synthetase
EQW00_06125	ENOG4105C9M	aspartyl-trna synthetase
EQW00_06135	ENOG4105CUZ	uba thif-type nad fad binding protein
EQW00_06140	ENOG4105D1H	recombination factor protein RarA
EQW00_06155	ENOG4105DEN	Luciferase family
EQW00_06160	ENOG4105C3J	Cysteine desulfurase
EQW00_06165	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
EQW00_06175	ENOG4105C7H	Helicase, RecD TraA family
EQW00_06180	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
EQW00_06185	ENOG4105VBH	UPF0297 protein
EQW00_06190	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
EQW00_06195	ENOG4105VPH	UPF0473 protein
EQW00_06205	ENOG4105XYU	peptidase (U32 family)
EQW00_06210	ENOG4105CFP	Peptidase U32
EQW00_06215	ENOG4105DBI	uridine monophosphokinase
EQW00_06220	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
EQW00_06225	ENOG4108RS6	transposase
EQW00_06230	ENOG4105P4J	Allophanate hydrolase, subunit 1
EQW00_06240	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
EQW00_06245	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
EQW00_06250	ENOG4105E7W	lamb ycsf family protein
EQW00_06255	ENOG4105C5A	transporter
EQW00_06260	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
EQW00_06265	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
EQW00_06270	ENOG4105CQW	ribosome biogenesis GTPase YqeH
EQW00_06275	ENOG4105E2X	shikimate dehydrogenase
EQW00_06280	ENOG410812S	Rna-binding protein
EQW00_06285	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
EQW00_06290	ENOG4108WF2	Metal Dependent Phosphohydrolase
EQW00_06295	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
EQW00_06300	ENOG4108D32	Methyltransferase
EQW00_06310	ENOG4108UK2	deaminase
EQW00_06315	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
EQW00_06320	ENOG4105TQK	DNA polymerase iii, delta' subunit
EQW00_06325	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
EQW00_06330	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
EQW00_06335	ENOG4105CSA	Coproporphyrinogen iii oxidase
EQW00_06340	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
EQW00_06345	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EQW00_06350	ENOG4105CFG	Acts as a chaperone (By similarity)
EQW00_06355	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EQW00_06360	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
EQW00_06365	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
EQW00_06370	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
EQW00_06380	ENOG4105F7J	membrane-bound serine protease
EQW00_06385	ENOG4105DI5	UPF0365 protein
EQW00_06395	ENOG4105C9A	Phoh family
EQW00_06400	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
EQW00_06405	ENOG41080IJ	Diacylglycerol kinase
EQW00_06410	ENOG4105KG3	cytidine deaminase
EQW00_06415	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
EQW00_06420	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
EQW00_06425	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
EQW00_06435	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
EQW00_06440	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
EQW00_06445	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EQW00_06455	ENOG4105EGD	dinuclear metal center protein, YbgI family
EQW00_06460	ENOG4105C1J	atp-dependent rna helicase
EQW00_06465	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
EQW00_06470	ENOG4105FDK	ABC transporter
EQW00_06475	ENOG4105FAV	ABC, transporter
EQW00_06480	ENOG4105N80	Ferric uptake regulator, Fur family
EQW00_06485	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
EQW00_06495	ENOG4107RF6	penicillin-binding protein
EQW00_06500	ENOG4105WDJ	50S ribosomal protein L33
EQW00_06505	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
EQW00_06510	ENOG4107U91	Rhomboid family
EQW00_06540	ENOG4105D7Q	type ii secretion system
EQW00_06545	ENOG4106855	Competence protein
EQW00_06570	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
EQW00_06575	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
EQW00_06580	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EQW00_06585	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EQW00_06595	ENOG4105WZW	rhodanese family
EQW00_06600	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
EQW00_06615	ENOG4105DC7	peptidase M24
EQW00_06620	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
EQW00_06625	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
EQW00_06630	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
EQW00_06635	ENOG4105CAS	nag kinase
EQW00_06640	ENOG4105C8Y	Acetylornithine aminotransferase
EQW00_06650	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
EQW00_06655	ENOG4108ZSR	alkaline shock protein
EQW00_06660	ENOG4105M7K	Involved in the transcription termination process (By similarity)
EQW00_06665	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
EQW00_06670	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
EQW00_06680	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
EQW00_06685	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
EQW00_06700	ENOG4105CPP	Dehydrogenase, E1 component
EQW00_06705	ENOG4105C7S	Dehydrogenase
EQW00_06710	ENOG4108Y6J	UPF0403 protein
EQW00_06715	ENOG4108QEG	Membrane
EQW00_06720	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
EQW00_06725	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
EQW00_06745	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
EQW00_06750	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
EQW00_06755	ENOG4105II7	pyrroline-5-carboxylate reductase
EQW00_06765	ENOG4105CPC	Aldo Keto reductase
EQW00_06770	ENOG4108YZ4	nudix hydrolase
EQW00_06775	ENOG4105I3K	Ferric uptake regulator, Fur family
EQW00_06780	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EQW00_06790	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
EQW00_06795	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
EQW00_06800	ENOG4105FE9	pseudouridine synthase
EQW00_06805	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EQW00_06810	ENOG4105BZU	Histidine kinase
EQW00_06835	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EQW00_06840	ENOG4106BU8	elastin-binding protein ebpS
EQW00_06845	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
EQW00_06850	ENOG4107RB3	L-asparaginase
EQW00_06855	ENOG4105CAT	Cytidine monophosphate kinase
EQW00_06860	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
EQW00_06865	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
EQW00_06870	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
EQW00_06875	ENOG4105K70	DNA-binding protein
EQW00_06885	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EQW00_06895	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
EQW00_06900	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
EQW00_06905	ENOG4105D49	3-dehydroquinate synthase
EQW00_06910	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
EQW00_06920	ENOG4105QKB	UPF0302 protein
EQW00_06935	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
EQW00_06940	ENOG4105CPK	Glycosyl transferase (Group 1
EQW00_06945	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EQW00_06950	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
EQW00_06955	ENOG4105DVT	helicase
EQW00_06960	ENOG4105C5S	asparaginyl-tRNA synthetase
EQW00_06970	ENOG4105CSM	endonuclease III
EQW00_06980	ENOG4105BZ4	penicillin-binding protein
EQW00_06985	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
EQW00_06995	ENOG4108UKS	UPF0398 protein
EQW00_07000	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
EQW00_07010	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
EQW00_07020	ENOG410890F	Dynamin family
EQW00_07030	ENOG41063K0	cell wall associated fibronectin-binding protein
EQW00_07050	ENOG4106QQ5	PBS lyase HEAT domain protein repeat-containing protein
EQW00_07055	ENOG4108Y6J	UPF0403 protein
EQW00_07065	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
EQW00_07075	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
EQW00_07085	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
EQW00_07090	ENOG4105E0X	reductase
EQW00_07095	ENOG4105C5Y	PTS System
EQW00_07100	ENOG4106E6V	UPF0346 protein
EQW00_07105	ENOG4105CN1	protease
EQW00_07120	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
EQW00_07125	ENOG410841Q	phosphoesterase PA-phosphatase related protein
EQW00_07130	ENOG4108IJ9	(ABC) transporter
EQW00_07145	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
EQW00_07155	ENOG4105UQX	Mate efflux family protein
EQW00_07160	ENOG4105E98	transcriptional regulator DeoR family
EQW00_07170	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EQW00_07175	ENOG4105GR3	Histidine kinase
EQW00_07185	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
EQW00_07190	ENOG4105C7S	Dehydrogenase
EQW00_07210	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
EQW00_07215	ENOG4107T89	von Willebrand factor, type A
EQW00_07220	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
EQW00_07225	ENOG4105CDW	Resistance protein
EQW00_07235	ENOG410855V	Acylphosphatase
EQW00_07245	ENOG4105VEQ	Cold shock protein
EQW00_07260	ENOG4105CJ1	ABC, transporter
EQW00_07270	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
EQW00_07275	ENOG4108XFP	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
EQW00_07280	ENOG4105CH2	amidohydrolase
EQW00_07285	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
EQW00_07290	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
EQW00_07295	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EQW00_07300	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
EQW00_07305	ENOG4105CFH	Aspartokinase
EQW00_07310	ENOG4105C5H	ABC transporter
EQW00_07315	ENOG4105QNR	S1 RNA binding domain protein
EQW00_07320	ENOG4105CVA	phosphate
EQW00_07325	ENOG4105C8U	phosphate abc transporter
EQW00_07330	ENOG4105E2Z	phosphate ABC transporter (Permease
EQW00_07335	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
EQW00_07340	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
EQW00_07360	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EQW00_07380	ENOG4108TV1	Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity)
EQW00_07385	ENOG4108RMH	femAB family
EQW00_07400	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
EQW00_07405	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
EQW00_07410	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
EQW00_07415	ENOG4105DK0	Indole-3-glycerol phosphate synthase
EQW00_07420	ENOG4108I0Q	anthranilate phosphoribosyltransferase
EQW00_07425	ENOG4105DDQ	anthranilate synthase
EQW00_07430	ENOG4105CRQ	synthase (Component I)
EQW00_07435	ENOG4105EVN	Prephenate dehydrogenase
EQW00_07440	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
EQW00_07445	ENOG41069HH	4-oxalocrotonate tautomerase
EQW00_07455	ENOG4108RCF	TRANSCRIPTIONal
EQW00_07460	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
EQW00_07465	ENOG4105FF5	Membrane
EQW00_07475	ENOG4105CID	antiterminator
EQW00_07485	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EQW00_07490	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EQW00_07495	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
EQW00_07510	ENOG4108I0Z	Aconitate hydratase
EQW00_07515	ENOG4105C94	Transporter
EQW00_07520	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
EQW00_07525	ENOG4105EYH	Exonuclease
EQW00_07530	ENOG4107RFY	SbcCD D subunit
EQW00_07545	ENOG4105CV1	Transketolase (EC 2.2.1.1)
EQW00_07550	ENOG4105VPS	UPF0291 protein
EQW00_07560	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
EQW00_07570	ENOG4106UY4	Inherit from COG: Scp-like extracellular
EQW00_07575	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
EQW00_07580	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
EQW00_07590	ENOG4105CH6	catalase
EQW00_07595	ENOG4108IQI	permease
EQW00_07610	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
EQW00_07615	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
EQW00_07620	ENOG4105D6E	homoserine dehydrogenase
EQW00_07625	ENOG4105CFH	Aspartokinase
EQW00_07655	ENOG4108ZGX	Histidine kinase
EQW00_07665	ENOG4105CJ1	ABC, transporter
EQW00_07670	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
EQW00_07705	ENOG4105C5F	glutamine synthetase
EQW00_07710	ENOG4105KV4	Transcriptional regulator
EQW00_07715	ENOG4105CXI	aluminum resistance protein
EQW00_07720	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
EQW00_07725	ENOG4108V06	Glutathione peroxidase
EQW00_07730	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
EQW00_07735	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
EQW00_07745	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
EQW00_07750	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
EQW00_07760	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
EQW00_07765	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
EQW00_07770	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
EQW00_07785	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
EQW00_07795	ENOG4105K7W	phage-related replication protein
EQW00_07800	ENOG4105DQU	oxidoreductase, subunit beta
EQW00_07805	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
EQW00_07810	ENOG4105D48	metallophosphoesterase
EQW00_07820	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
EQW00_07825	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
EQW00_07835	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
EQW00_07850	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
EQW00_07865	ENOG4105FDP	GntR family transcriptional regulator
EQW00_07870	ENOG4105CNU	cell division protein FtsK
EQW00_07875	ENOG4105CN5	Metallo-Beta-Lactamase
EQW00_07880	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
EQW00_07885	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
EQW00_07890	ENOG4105DTN	riboflavin biosynthesis protein ribF
EQW00_07895	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
EQW00_07900	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
EQW00_07905	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
EQW00_07910	ENOG4105VHM	ribosomal protein
EQW00_07915	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
EQW00_07920	ENOG4105CHV	Transcription elongation factor NusA
EQW00_07925	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
EQW00_07930	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
EQW00_07935	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
EQW00_07945	ENOG4105KNE	Phosphatidate cytidylyltransferase
EQW00_07950	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
EQW00_07955	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
EQW00_07960	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
EQW00_07965	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
EQW00_07970	ENOG4105CE9	30S ribosomal protein S2
EQW00_07975	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
EQW00_07980	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
EQW00_07985	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
EQW00_07990	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EQW00_07995	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
EQW00_08000	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
EQW00_08005	ENOG4105C79	DNA protecting protein DprA
EQW00_08010	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
EQW00_08015	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
EQW00_08020	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EQW00_08035	ENOG4105EJV	Membrane
EQW00_08045	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
EQW00_08050	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
EQW00_08055	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
EQW00_08060	ENOG4105K5M	30s ribosomal protein S16
EQW00_08070	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
EQW00_08075	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EQW00_08080	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
EQW00_08085	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
EQW00_08090	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
EQW00_08095	ENOG4105CHR	reductase
EQW00_08105	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
EQW00_08110	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
EQW00_08115	ENOG4105CB5	ATP-dependent DNA helicase recG
EQW00_08120	ENOG4105DP4	dak2 domain fusion protein ylov
EQW00_08125	ENOG4108ZAA	Alkaline-shock protein
EQW00_08130	ENOG4105VB9	50S ribosomal protein l28
EQW00_08140	ENOG4105DJV	ribulose-phosphate 3-epimerase
EQW00_08145	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
EQW00_08155	ENOG4108ZF3	Phosphatase
EQW00_08160	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EQW00_08165	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
EQW00_08170	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
EQW00_08175	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
EQW00_08185	ENOG4105C25	Primosomal protein n'
EQW00_08190	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
EQW00_08195	ENOG41067UH	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
EQW00_08200	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
EQW00_08205	ENOG4105F23	Fibronectin-binding protein
EQW00_08220	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
EQW00_08225	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
EQW00_08230	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
EQW00_08235	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
EQW00_08240	ENOG4105CD3	dihydroorotase
EQW00_08245	ENOG4105CXT	aspartate transcarbamylase
EQW00_08255	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
EQW00_08260	ENOG4105C34	Pseudouridine synthase
EQW00_08265	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
EQW00_08280	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
EQW00_08295	ENOG41067XK	integral membrane protein
EQW00_08300	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
EQW00_08305	ENOG4105DFA	alanine racemase domain protein
EQW00_08310	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
EQW00_08315	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
EQW00_08320	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
EQW00_08325	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
EQW00_08330	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
EQW00_08335	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
EQW00_08340	ENOG4105CJN	penicillin-binding protein
EQW00_08345	ENOG41068DC	Essential cell division protein (By similarity)
EQW00_08350	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
EQW00_08355	ENOG4108V6E	Cell division protein mraZ
EQW00_08360	ENOG41074B2	UPF0747 protein
EQW00_08365	ENOG4108YG3	N-acetyltransferase
EQW00_08405	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
EQW00_08410	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
EQW00_08415	ENOG4105E33	succinate dehydrogenase
EQW00_08425	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
EQW00_08435	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
EQW00_08440	ENOG4105K63	Thioredoxin
EQW00_08445	ENOG4105C98	muts2 protein
EQW00_08450	ENOG4105DCG	PHP domain protein
EQW00_08460	ENOG410687F	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
EQW00_08465	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EQW00_08470	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
EQW00_08475	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
EQW00_08480	ENOG4108RWN	rrna methyltransferase
EQW00_08490	ENOG4108M1Z	surface protein
EQW00_08495	ENOG41067VY	50S ribosomal protein L32
EQW00_08510	ENOG4105CDE	UPF0348 protein
EQW00_08515	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
EQW00_08520	ENOG4106H78	methyltransferase
EQW00_08530	ENOG4105WUC	UPF0298 protein
EQW00_08540	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
EQW00_08550	ENOG4106UY4	Inherit from COG: Scp-like extracellular
EQW00_08560	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
EQW00_08565	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
EQW00_08570	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
EQW00_08575	ENOG4105CNI	cell division protein FtsW
EQW00_08580	ENOG4105ZPI	UPF0358 protein
EQW00_08605	ENOG4105CI3	gtp-binding protein typa
EQW00_08615	ENOG4105ECY	inositol monophosphatase
EQW00_08620	ENOG4108WQ8	UPF0637 protein
EQW00_08625	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
EQW00_08650	ENOG4105F38	ABC transporter, permease
EQW00_08655	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EQW00_08665	ENOG4105WBI	UPF0223 protein
EQW00_08670	ENOG4107QN2	dihydrolipoyl dehydrogenase
EQW00_08675	ENOG4105C7S	Dehydrogenase
EQW00_08680	ENOG4105CPP	Dehydrogenase, E1 component
EQW00_08685	ENOG4107RUY	(E1 component), alpha subunit
EQW00_08695	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
EQW00_08700	ENOG4106148	UPF0356 protein
EQW00_08705	ENOG4105CN5	Metallo-Beta-Lactamase
EQW00_08710	ENOG4107ZYR	domain protein
EQW00_08730	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
EQW00_08745	ENOG4105DR4	Methyltransferase
EQW00_08760	ENOG4105CCI	Myosin-Cross-Reactive Antigen
EQW00_08770	ENOG4108JJB	ABC transporter
EQW00_08775	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
EQW00_08780	ENOG4105C12	Phosphoribosylglycinamide synthetase
EQW00_08785	ENOG4105DC1	bifunctional purine biosynthesis protein purh
EQW00_08790	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
EQW00_08795	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
EQW00_08800	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
EQW00_08805	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
EQW00_08810	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
EQW00_08815	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
EQW00_08820	ENOG4105C8V	SAICAR synthetase
EQW00_08825	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
EQW00_08830	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
EQW00_08835	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
EQW00_08845	ENOG4105E2S	oxidase) subunit II
EQW00_08850	ENOG4105BZ9	Cytochrome C oxidase, subunit I
EQW00_08855	ENOG4105CCU	oxidase (Subunit III)
EQW00_08860	ENOG41060D1	Quinol oxidase
EQW00_08870	ENOG4108A04	Beta-lactamase
EQW00_08875	ENOG4108KGH	TRANSCRIPTIONal
EQW00_08885	ENOG41082BV	acetyltransferase
EQW00_08890	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
EQW00_08900	ENOG4108TGC	Acyltransferase
EQW00_08905	ENOG4105CHM	Aminotransferase
EQW00_08910	ENOG4108IPT	Naphthoate synthase
EQW00_08920	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
EQW00_08925	ENOG4105E4F	Isochorismate synthase
EQW00_08935	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
EQW00_08945	ENOG4108MK9	spermidine N(1)-acetyltransferase
EQW00_08955	ENOG4105YB8	TM2 domain containing protein
EQW00_08985	ENOG4106PHI	plasmid recombination enzyme
EQW00_09040	ENOG4105CGH	5'-nucleotidase
EQW00_09055	ENOG4107TS3	membrane protein, TerC
EQW00_09060	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
EQW00_09070	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
EQW00_09075	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
EQW00_09080	ENOG4108PK2	permease that is required for glycolipid anchoring of LTA. May facilitate the transport of diglucosyl- diacylglycerol (Glc2-DAG) from the inner to the outer leaflet of the cytoplasmic membrane, delivering Glc2-DAG as a substrate for LTA synthesis, thereby generating glycolipid-anchored LTA. Appears to play an important role in virulence
EQW00_09095	ENOG4105C02	permease
EQW00_09105	ENOG4108RS6	transposase
EQW00_09125	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
EQW00_09125	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
EQW00_09135	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
EQW00_09140	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
EQW00_09145	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
EQW00_09150	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
EQW00_09185	ENOG4105CJW	magnesium transporter
EQW00_09190	ENOG4105EMS	pseudouridine synthase
EQW00_09195	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
EQW00_09205	ENOG4106EFP	UPF0738 protein
EQW00_09215	ENOG4108Z18	K06886 hemoglobin
EQW00_09220	ENOG4105T58	Dithiol-disulfide isomerase
EQW00_09225	ENOG4105DPN	Oligoendopeptidase f
EQW00_09235	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
EQW00_09240	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
EQW00_09245	ENOG4105C31	Tryptophanyl-tRNA synthetase
EQW00_09255	ENOG4108JQ7	(ABC) transporter
EQW00_09265	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EQW00_09270	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EQW00_09280	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
EQW00_09285	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
EQW00_09295	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EQW00_09310	ENOG4108KP7	hydrolase
EQW00_09315	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
EQW00_09320	ENOG4106BKT	UPF0344 protein
EQW00_09325	ENOG4105ERH	Fumarylacetoacetate hydrolase
EQW00_09330	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
EQW00_09335	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EQW00_09340	ENOG4105C3F	Signal peptidase i
EQW00_09355	ENOG4107QYV	phosphohexose isomerase
EQW00_09360	ENOG4105CDH	Citrulline--aspartate ligase
EQW00_09365	ENOG4105CH7	arginosuccinase
EQW00_09370	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
EQW00_09375	ENOG4105D82	Glutamate dehydrogenase
EQW00_09380	ENOG4105C8Y	Acetylornithine aminotransferase
EQW00_09390	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EQW00_09395	ENOG41060GV	RNA binding s1 domain protein
EQW00_09400	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
EQW00_09410	ENOG4105D65	subunit l
EQW00_09420	ENOG4105MKQ	Monovalent cation H antiporter subunit C
EQW00_09425	ENOG4108JPZ	Monovalent cation H antiporter subunit D
EQW00_09430	ENOG4105SC1	monovalent cation H antiporter subunit E
EQW00_09435	ENOG4105W4C	monovalent cation H antiporter subunit F
EQW00_09440	ENOG4105KJM	monovalent cation h antiporter subunit g
EQW00_09450	ENOG4105KA0	thioesterase Superfamily protein
EQW00_09460	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
EQW00_09470	ENOG4105CEP	NADH dehydrogenase
EQW00_09475	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
EQW00_09480	ENOG4105ZKE	UPF0349 protein
EQW00_09495	ENOG41083MR	nifu domain-containing protein
EQW00_09500	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
EQW00_09505	ENOG4106C1H	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
EQW00_09510	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
EQW00_09515	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
EQW00_09525	ENOG4105C5I	Dehydrogenase
EQW00_09530	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
EQW00_09545	ENOG4105MMD	transcriptional regulator
EQW00_09550	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
EQW00_09555	ENOG4107R8B	5'-nucleotidase
EQW00_09565	ENOG4105I3N	Conserved Protein
EQW00_09585	ENOG4105DIW	FeS assembly protein SUFB
EQW00_09590	ENOG4108UNV	SUF system FeS assembly protein, NifU family
EQW00_09595	ENOG4105C9B	Cysteine desulfurase
EQW00_09600	ENOG4105JRK	feS assembly protein SufD
EQW00_09605	ENOG4105C3K	feS assembly ATPase SufC
EQW00_09615	ENOG41061M1	UPF0337 protein
EQW00_09625	ENOG4105D01	(LipO)protein
EQW00_09630	ENOG4108UMI	ABC transporter, permease
EQW00_09635	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
EQW00_09655	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
EQW00_09660	ENOG41080E8	Transcriptional regulator, Spx MgsR family
EQW00_09665	ENOG4105SZ6	Thioredoxin
EQW00_09675	ENOG4105FF2	Type I DHQase
EQW00_09680	ENOG4108ZHJ	Organic hydroperoxide resistance protein
EQW00_09735	ENOG4105K7W	phage-related replication protein
EQW00_09750	ENOG4105VEQ	Cold shock protein
EQW00_09760	ENOG4105PGM	cation diffusion facilitator family transporter
EQW00_09790	ENOG4105CZN	Potassium uptake protein
EQW00_09825	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
EQW00_09830	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
EQW00_09840	ENOG4105XZU	Preprotein translocase, subunit SecG
EQW00_09850	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
EQW00_09855	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
EQW00_09860	ENOG4105CP7	Triose-phosphate isomerase
EQW00_09865	ENOG4105BZA	Phosphoglycerate kinase
EQW00_09870	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
EQW00_09890	ENOG4105ECP	epimerase
EQW00_09900	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
EQW00_09910	ENOG4105CIE	May be required for sporulation (By similarity)
EQW00_09915	ENOG4105CHW	UPF0052 protein
EQW00_09920	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
EQW00_09925	ENOG4105C3M	thioredoxin reductase
EQW00_09940	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
EQW00_09945	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
EQW00_09950	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
EQW00_09955	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
EQW00_09975	ENOG41068JE	domain protein
EQW00_09985	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
EQW00_09990	ENOG4105MS2	ribosomal subunit Interface protein
EQW00_09995	ENOG41081UC	Inherit from COG: Competence protein
EQW00_10010	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
EQW00_10015	ENOG4105ESV	Glycosyl transferase, family 4
EQW00_10020	ENOG4105BZU	Histidine kinase
EQW00_10035	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
EQW00_10040	ENOG4105BZW	Glycerate kinase
EQW00_10060	ENOG4105D4A	Cell wall formation (By similarity)
EQW00_10075	ENOG4108IPW	abc transporter atp-binding protein
EQW00_10080	ENOG4105CM4	permease protein
EQW00_10085	ENOG4105DHS	permease protein
EQW00_10095	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
EQW00_10100	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
EQW00_10105	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
EQW00_10115	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
EQW00_10120	ENOG4105DUX	Transporter
EQW00_10125	ENOG4109050	May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG)
EQW00_10130	ENOG4108EKI	Dehydrogenase
EQW00_10135	ENOG4108ZIE	5 nucleotidase deoxy cytosolic type C
EQW00_10140	ENOG4105CIH	Imidazole acetol-phosphate transaminase
EQW00_10145	ENOG4105E90	ABC transporter
EQW00_10150	ENOG4108IJ8	ABC transporter
EQW00_10155	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EQW00_10160	ENOG4105C5H	ABC transporter
EQW00_10175	ENOG4105E0M	Sulfatase
EQW00_10185	ENOG4105P4J	Allophanate hydrolase, subunit 1
EQW00_10200	ENOG4105CRQ	synthase (Component I)
EQW00_10205	ENOG4105DDQ	anthranilate synthase
EQW00_10210	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
EQW00_10215	ENOG4107ZAE	6-carboxy-5,6,7,8-tetrahydropterin synthase
EQW00_10220	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
EQW00_10245	ENOG4108WZ2	response regulator
EQW00_10250	ENOG4108YBA	Histidine kinase
EQW00_10255	ENOG4105CKK	Glycosyl transferase, family 2
EQW00_10270	ENOG4105C37	(CBS) domain
EQW00_10275	ENOG4105CE4	GlcNAc 6-P deacetylase
EQW00_10280	ENOG4105DM4	PTS System
EQW00_10285	ENOG4105DE4	1-phosphofructokinase
EQW00_10290	ENOG4105E98	transcriptional regulator DeoR family
EQW00_10300	ENOG4108Z66	YbaK ebsC protein
EQW00_10310	ENOG4105DP8	Major facilitator superfamily MFS_1
EQW00_10325	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
EQW00_10330	ENOG4107QPK	)-transporter
EQW00_10335	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
EQW00_10355	ENOG41083AI	transcriptional regulator), MarR family
EQW00_10360	ENOG4108JJ8	(ABC) transporter
EQW00_10365	ENOG4108JJ9	ABC, transporter
EQW00_10370	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
EQW00_10385	ENOG4107XJU	UPF0178 protein
EQW00_10390	ENOG4108URH	decarboxylase
EQW00_10415	ENOG4105SXS	Protein of unknown function (DUF456)
EQW00_10420	ENOG4105S8Q	sugar efflux transporter
EQW00_10445	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
EQW00_10455	ENOG4105CDY	transcriptional regulatory protein
EQW00_10475	ENOG4105VRS	hydrolase family 18
EQW00_10480	ENOG4105CJ3	phosphate transporter
EQW00_10485	ENOG4107GRR	phosphate transport regulator
EQW00_10495	ENOG4105C19	ABC transporter
EQW00_10500	ENOG4105EWM	Histidine kinase
EQW00_10505	ENOG4105CJZ	response regulator
EQW00_10525	ENOG4108K88	Membrane
EQW00_10535	ENOG4105E0A	ABC, transporter
EQW00_10540	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
EQW00_10555	ENOG4105BZ1	(ABC) transporter
EQW00_10570	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
EQW00_10590	ENOG4105EY8	ABC transporter
EQW00_10595	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
EQW00_10605	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
EQW00_10610	ENOG4105DIK	(ABC) transporter
EQW00_10615	ENOG4105CC5	ABC transporter
EQW00_10620	ENOG4105DSE	periplasmic solute binding protein
EQW00_10625	ENOG4105EEQ	Na H antiporter
EQW00_10635	ENOG410684G	monovalent cation H antiporter subunit F
EQW00_10640	ENOG4105IMY	monovalent cation H antiporter subunit E
EQW00_10645	ENOG4108JPZ	Monovalent cation H antiporter subunit D
EQW00_10650	ENOG4105MKQ	Monovalent cation H antiporter subunit C
EQW00_10655	ENOG4108PMQ	Na H antiporter MnhB subunit-related protein
EQW00_10660	ENOG4105C8S	subunit m
EQW00_10700	ENOG4105F2Z	3-oxoadipate enol-lactonase
EQW00_10720	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
EQW00_10725	ENOG4105EHG	Permease protein
EQW00_10730	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
EQW00_10740	ENOG4107TXC	Transcriptional regulator
EQW00_10745	ENOG4105CSM	endonuclease III
EQW00_10750	ENOG4105C75	arginyL-tRNA synthetase
EQW00_10775	ENOG4105DQ4	alcohol dehydrogenase
EQW00_10780	ENOG4105QUH	Domain of unknown function (DUF2088)
EQW00_10785	ENOG4105DVM	PP-loop domain protein
EQW00_10790	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
EQW00_10795	ENOG4105C8M	UPF0272 protein
EQW00_10800	ENOG4108XFG	YwhD family
EQW00_10805	ENOG4105DCI	Phosphohydrolase
EQW00_10815	ENOG4105CPC	Aldo Keto reductase
EQW00_10825	ENOG4107QN2	dihydrolipoyl dehydrogenase
EQW00_10830	ENOG4105QAT	UPF0741 protein
EQW00_10850	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
EQW00_10855	ENOG4108IJ2	phosphate acetyltransferase
EQW00_10860	ENOG4107JTW	chlorite dismutase
EQW00_10875	ENOG4105CUB	amino acid
EQW00_10880	ENOG4105M08	Membrane
EQW00_10890	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
EQW00_10900	ENOG4105DWF	phosphomethylpyrimidine kinase
EQW00_10920	ENOG4105CHU	acetyl-coa acetyltransferase
EQW00_10925	ENOG4107F3J	Amp-dependent synthetase and ligase
EQW00_10935	ENOG41080HJ	6-phospho 3-hexuloisomerase
EQW00_10940	ENOG4108VA3	3-hexulose-6-phosphate synthase
EQW00_10945	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
EQW00_10955	ENOG4107YEI	lmbE family
EQW00_10960	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
EQW00_10970	ENOG4108KUF	arsenical pump membrane protein
EQW00_10975	ENOG4108KUF	arsenical pump membrane protein
EQW00_10980	ENOG4108UXE	Protein tyrosine phosphatase
EQW00_10990	ENOG4105DUY	Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein
EQW00_10990	ENOG4105DUY	Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein
EQW00_10995	ENOG4107YFT	Nadph-dependent fmn reductase
EQW00_11000	ENOG410667J	hydrolase
EQW00_11010	ENOG4108Z6B	deaminase
EQW00_11020	ENOG4105ZMH	deoxynucleoside kinase
EQW00_11025	ENOG4105CHR	reductase
EQW00_11030	ENOG4105CPU	Monooxygenase
EQW00_11035	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
EQW00_11040	ENOG4107RZX	Teichoic acid biosynthesis protein
EQW00_11045	ENOG4105EJJ	Dehydrogenase
EQW00_11050	ENOG4108QHG	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
EQW00_11055	ENOG4105CM2	brancheD-chain amino acid aminotransferase
EQW00_11085	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
EQW00_11090	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
EQW00_11100	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
EQW00_11110	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EQW00_11115	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EQW00_11120	ENOG4107Y49	methyltransferase
EQW00_11125	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
EQW00_11130	ENOG4108VZM	50s ribosomal protein L10
EQW00_11140	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
EQW00_11145	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
EQW00_11150	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
EQW00_11155	ENOG410683Z	Preprotein translocase SecE subunit
EQW00_11160	ENOG4107FTN	50S ribosomal protein L33
EQW00_11170	ENOG4105M0M	Tetracycline resistance protein
EQW00_11175	ENOG4105C2N	RNA methyltransferase TrmH family group 3
EQW00_11180	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EQW00_11185	ENOG4105C8N	cysteinyl-tRNA synthetase
EQW00_11190	ENOG4105D7W	serine acetyltransferase
EQW00_11195	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
EQW00_11200	ENOG4105CTP	PilT protein domain protein
EQW00_11205	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
EQW00_11210	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EQW00_11215	ENOG41066A3	ATP guanido phosphotransferase
EQW00_11220	ENOG4108Z0C	Uvrb UvrC protein
EQW00_11225	ENOG4105KEX	transcriptional regulator, ctsr
EQW00_11230	ENOG4105D9N	nucleoside
EQW00_11240	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
EQW00_11245	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
EQW00_11250	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
EQW00_11335	ENOG4105CRK	lysyL-tRNA synthetase
EQW00_11340	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EQW00_11345	ENOG4105KRF	dihydroneopterin aldolase
EQW00_11350	ENOG4105EEI	dihydropteroate synthase
EQW00_11355	ENOG4105C6T	cysteine synthase
EQW00_11360	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
EQW00_11365	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EQW00_11370	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
EQW00_11375	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
EQW00_11380	ENOG41060GV	RNA binding s1 domain protein
EQW00_11390	ENOG41082I2	s4 domain protein
EQW00_11395	ENOG4108IY2	MazG family
EQW00_11405	ENOG4108JA2	transcriptioN-repair coupling factor
EQW00_11410	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
EQW00_11415	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
EQW00_11420	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
EQW00_11425	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
EQW00_11430	ENOG4105K4W	Could be involved in septation (By similarity)
EQW00_11435	ENOG4105KME	endoribonuclease L-psp
EQW00_11440	ENOG4105DFT	pur operon repressor
EQW00_11445	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
EQW00_11450	ENOG4105W42	Veg protein
EQW00_11455	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
EQW00_11460	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
EQW00_11465	ENOG4105F8V	Hydrolase, tatD family
EQW00_11470	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
EQW00_11475	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
EQW00_11480	ENOG4105VC4	domain protein
EQW00_11485	ENOG41060K3	Methyltransferase
EQW00_11490	ENOG4105QD5	Involved in initiation control of chromosome replication (By similarity)
EQW00_11495	ENOG4105MA4	psp1 domain protein
EQW00_11500	ENOG4105FA2	dna polymerase iii
EQW00_11505	ENOG4105X0R	protein from nitrogen regulatory protein P-II
EQW00_11510	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
EQW00_11515	ENOG4105CXN	decarboxylase
EQW00_11540	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
EQW00_11545	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
EQW00_11550	ENOG4105C6E	dna polymerase iii
EQW00_11570	ENOG4105HMI	Membrane
EQW00_11585	ENOG4105BZ8	glutamate synthase
EQW00_11590	ENOG4105CBC	glutamate synthase
EQW00_11595	ENOG4106P55	Transcriptional regulator
EQW00_11625	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
EQW00_11630	ENOG41068JE	domain protein
EQW00_11635	ENOG4105D01	(LipO)protein
EQW00_11640	ENOG4108UMI	ABC transporter, permease
EQW00_11645	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
EQW00_11650	ENOG4105C28	cystathionine
EQW00_11665	ENOG4105C8J	)-transporter
EQW00_11690	ENOG4105GPN	Uncharacterized conserved protein (DUF2294)
EQW00_11700	ENOG4105EVH	UPF0753 protein
EQW00_11705	ENOG4108TWJ	NADH dehydrogenase subunit 5
EQW00_11725	ENOG4105CKI	cobalamin synthesis protein
EQW00_11780	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EQW00_11785	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
EQW00_11790	ENOG4105C2W	permease
EQW00_11795	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
EQW00_11820	ENOG4107R6U	sodium dicarboxylate symporter
EQW00_11825	ENOG4108DBC	nitroreductase
EQW00_11835	ENOG4105D3R	alkyl hydroperoxide reductase
EQW00_11840	ENOG4108JU3	Alkyl hydroperoxide reductase
EQW00_11875	ENOG4105N14	lysine exporter protein LysE YggA
EQW00_11900	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
EQW00_11905	ENOG4108UUM	single-stranded DNA-binding protein
EQW00_11910	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
EQW00_11925	ENOG4105C3G	gtp-binding protein
EQW00_11930	ENOG4105VDK	protein, conserved in bacteria
EQW00_11935	ENOG4105D8X	mechanosensitive ion channel
EQW00_11940	ENOG4105FA0	parb-like partition protein
EQW00_11950	ENOG4105C28	cystathionine
EQW00_11955	ENOG4105C28	cystathionine
EQW00_11965	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
EQW00_11975	ENOG4105CHU	acetyl-coa acetyltransferase
EQW00_11990	ENOG4105VZ8	Transcriptional regulator
EQW00_12000	ENOG4108IUW	ABC transporter
EQW00_12035	ENOG4105DUY	Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein
EQW00_12035	ENOG4105DUY	Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein
EQW00_12045	ENOG4105C3F	Signal peptidase i
EQW00_12060	ENOG4105C19	ABC transporter
EQW00_12085	ENOG4107RBB	ABC transporter, permease
EQW00_12090	ENOG4105C19	ABC transporter
EQW00_12130	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
EQW00_12135	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
EQW00_12140	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
EQW00_12145	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
EQW00_12150	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
EQW00_12205	ENOG4105KTU	Transcriptional regulator, arsr family
EQW00_12250	ENOG4105CHH	sulfate transporter
EQW00_12255	ENOG4107YZX	Universal stress protein
EQW00_12275	ENOG4108PCX	Major Facilitator
EQW00_12285	ENOG4106PHI	plasmid recombination enzyme