locus-tag	class	description
HJH97_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HJH97_00010	COG0592	DNA-directed DNA polymerase activity
HJH97_00015	COG2501	S4 domain
HJH97_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HJH97_00025	COG0187	DNA topoisomerase II activity
HJH97_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HJH97_00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HJH97_00040	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HJH97_00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HJH97_00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
HJH97_00075	COG0359	binds to the 23S rRNA
HJH97_00080	COG0305	Participates in initiation and elongation during chromosome replication
HJH97_00085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HJH97_00100	COG0745	RESPONSE REGULATOR receiver
HJH97_00105	COG5002	protein histidine kinase activity
HJH97_00110	COG4863	YycH protein
HJH97_00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HJH97_00125	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HJH97_00130	COG2070	2-Nitropropane dioxygenase
HJH97_00140	COG0477	Major facilitator Superfamily
HJH97_00155	COG1914	H( )-stimulated, divalent metal cation uptake system
HJH97_00225	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HJH97_00235	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HJH97_00250	COG0456	acetyltransferase
HJH97_00295	COG0584	glycerophosphoryl diester phosphodiesterase
HJH97_00300	COG2030	dehydratase
HJH97_00375	COG2210	Belongs to the sulfur carrier protein TusA family
HJH97_00380	COG1937	Protein conserved in bacteria
HJH97_00385	COG0730	response to heat
HJH97_00390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HJH97_00395	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HJH97_00415	COG0640	Transcriptional regulator
HJH97_00430	COG0668	transmembrane transport
HJH97_00435	COG0561	phosphatase activity
HJH97_00465	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HJH97_00470	COG0579	oxidoreductase
HJH97_00475	COG1028	Short-chain dehydrogenase reductase Sdr
HJH97_00485	COG1755	Isoprenylcysteine carboxyl methyltransferase
HJH97_00495	COG2207	Transcriptional regulator
HJH97_00495	COG4753	response regulator
HJH97_00500	COG2972	Histidine kinase
HJH97_00555	COG4932	domain protein
HJH97_00555	COG3583	domain protein
HJH97_00555	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HJH97_00565	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HJH97_00570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HJH97_00575	COG0156	8-amino-7-oxononanoate synthase activity
HJH97_00580	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HJH97_00610	COG0523	cobalamin synthesis protein
HJH97_00635	COG3976	FMN-binding domain protein
HJH97_00635	COG1053	succinate dehydrogenase
HJH97_00635	COG0431	NADPH-dependent FMN reductase
HJH97_00645	COG1028	Short-chain dehydrogenase reductase Sdr
HJH97_00650	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HJH97_00680	COG0601	transmembrane transport
HJH97_00690	COG0444	Belongs to the ABC transporter superfamily
HJH97_00695	COG1124	(ABC) transporter
HJH97_00705	COG1882	Formate acetyltransferase
HJH97_00710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HJH97_00715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HJH97_00720	COG1114	Component of the transport system for branched-chain amino acids
HJH97_00725	COG1309	transcriptional regulator
HJH97_00730	COG3246	L-lysine catabolic process to acetate
HJH97_00735	COG1250	3-hydroxyacyl-CoA dehydrogenase
HJH97_00770	COG1288	antiporter activity
HJH97_00775	COG0549	Belongs to the carbamate kinase family
HJH97_00780	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HJH97_00790	COG0346	lactoylglutathione lyase activity
HJH97_00795	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
HJH97_00800	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HJH97_00810	COG2376	Dihydroxyacetone kinase
HJH97_00815	COG1461	Dihydroxyacetone kinase
HJH97_00820	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
HJH97_00835	COG2814	Major facilitator Superfamily
HJH97_00865	COG2814	Major facilitator Superfamily
HJH97_00880	COG2962	Rard protein
HJH97_00885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HJH97_00890	COG0471	metal ion transport
HJH97_00895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HJH97_00900	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HJH97_00905	COG0022	dehydrogenase e1 component
HJH97_00910	COG0508	dehydrogenase complex catalyzes the overall conversion of
HJH97_00935	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HJH97_00940	COG1054	Belongs to the UPF0176 family
HJH97_00945	COG3386	PFAM SMP-30 Gluconolaconase
HJH97_00950	COG2353	YceI-like domain
HJH97_00955	COG0579	oxidoreductase
HJH97_00980	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HJH97_00985	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HJH97_00990	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HJH97_00995	COG0131	Imidazoleglycerol-phosphate dehydratase
HJH97_01000	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HJH97_01005	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HJH97_01010	COG0107	imidazoleglycerol-phosphate synthase activity
HJH97_01015	COG0140	phosphoribosyl-ATP diphosphatase activity
HJH97_01015	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HJH97_01020	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HJH97_01025	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HJH97_01035	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HJH97_01040	COG4463	regulation of RNA biosynthetic process
HJH97_01045	COG3880	PFAM UvrB UvrC protein
HJH97_01050	COG3869	Catalyzes the specific phosphorylation of arginine residues in
HJH97_01055	COG0542	response to heat
HJH97_01060	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HJH97_01065	COG4956	integral membrane protein (PIN domain superfamily)
HJH97_01070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HJH97_01075	COG1045	serine acetyltransferase
HJH97_01080	COG0215	cysteine-tRNA ligase activity
HJH97_01085	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HJH97_01090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HJH97_01095	COG3688	RNA-binding protein containing a PIN domain
HJH97_01105	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HJH97_01110	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HJH97_01115	COG0250	Participates in transcription elongation, termination and antitermination
HJH97_01120	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HJH97_01125	COG0081	regulation of translation
HJH97_01130	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HJH97_01135	COG0222	ribosome binding
HJH97_01140	COG2813	Specifically methylates the guanine in position
HJH97_01145	COG0085	RNA polymerase activity
HJH97_01150	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HJH97_01160	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HJH97_01170	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HJH97_01175	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HJH97_01180	COG1473	amidohydrolase
HJH97_01200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HJH97_01205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HJH97_01210	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HJH97_01215	COG1063	alcohol dehydrogenase
HJH97_01220	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HJH97_01225	COG0546	phosphoglycolate phosphatase activity
HJH97_01230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HJH97_01235	COG1028	Short-chain dehydrogenase reductase Sdr
HJH97_01240	COG1428	Deoxynucleoside kinase
HJH97_01245	COG1428	Deoxynucleoside kinase
HJH97_01255	COG0561	phosphatase activity
HJH97_01260	COG0431	NADPH-dependent FMN reductase
HJH97_01290	COG1469	GTP cyclohydrolase I activity
HJH97_01295	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HJH97_01310	COG0363	glucosamine-6-phosphate deaminase activity
HJH97_01315	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HJH97_01320	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HJH97_01330	COG0318	PFAM AMP-dependent synthetase and ligase
HJH97_01335	COG0183	Belongs to the thiolase family
HJH97_01355	COG0351	phosphomethylpyrimidine kinase
HJH97_01365	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HJH97_01375	COG2363	Small membrane protein
HJH97_01380	COG0531	amino acid
HJH97_01400	COG3253	May function as heme-dependent peroxidase
HJH97_01405	COG0280	phosphate acetyltransferase
HJH97_01410	COG0095	Lipoate-protein ligase
HJH97_01430	COG4844	belongs to the
HJH97_01435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HJH97_01445	COG0667	Aldo Keto reductase
HJH97_01450	COG2409	Drug exporters of the RND superfamily
HJH97_01455	COG2113	Glycine betaine
HJH97_01475	COG1078	dGTPase activity
HJH97_01485	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HJH97_01490	COG1691	(AIR) carboxylase
HJH97_01495	COG1606	tRNA processing
HJH97_01500	COG3875	lactate racemase activity
HJH97_01505	COG1064	alcohol dehydrogenase
HJH97_01520	COG0018	arginyl-trna synthetase
HJH97_01525	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HJH97_01535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HJH97_01540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HJH97_01545	COG0546	phosphoglycolate phosphatase activity
HJH97_01565	COG0596	Alpha beta hydrolase
HJH97_01595	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HJH97_01595	COG2111	Na H antiporter
HJH97_01600	COG2111	Na H antiporter
HJH97_01605	COG1006	Multisubunit Na H antiporter MnhC subunit
HJH97_01610	COG0651	ATP synthesis coupled electron transport
HJH97_01615	COG1863	multisubunit Na H antiporter MnhE subunit
HJH97_01620	COG2212	antiporter activity
HJH97_01625	COG1320	monovalent cation:proton antiporter activity
HJH97_01635	COG0803	Belongs to the bacterial solute-binding protein 9 family
HJH97_01640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HJH97_01645	COG1121	(ABC) transporter
HJH97_01650	COG1321	iron dependent repressor
HJH97_01660	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HJH97_01665	COG1134	teichoic acid transport
HJH97_01670	COG1682	transport, permease protein
HJH97_01675	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HJH97_01685	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HJH97_01690	COG1132	(ABC) transporter
HJH97_01695	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HJH97_01705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HJH97_01710	COG1120	ATPase activity
HJH97_01720	COG3949	Membrane
HJH97_01735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HJH97_01740	COG0745	RESPONSE REGULATOR receiver
HJH97_01745	COG2205	protein histidine kinase activity
HJH97_01750	COG1136	(ABC) transporter
HJH97_01755	COG0577	efflux transmembrane transporter activity
HJH97_01760	COG1392	Phosphate transport regulator
HJH97_01765	COG0306	phosphate transporter
HJH97_01770	COG3942	CHAP domain
HJH97_01770	COG1388	LysM domain
HJH97_01790	COG0217	transcriptional regulatory protein
HJH97_01800	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
HJH97_01820	COG0583	DNA-binding transcription factor activity
HJH97_01825	COG2814	Major facilitator Superfamily
HJH97_01830	COG2839	Protein conserved in bacteria
HJH97_01855	COG1611	Belongs to the LOG family
HJH97_01860	COG1671	Belongs to the UPF0178 family
HJH97_01875	COG1968	undecaprenyl-diphosphatase activity
HJH97_01880	COG4988	ABC transporter
HJH97_01885	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HJH97_01905	COG0039	L-malate dehydrogenase activity
HJH97_01910	COG0471	metal ion transport
HJH97_01915	COG0415	Belongs to the DNA photolyase family
HJH97_01940	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HJH97_01945	COG1349	DNA-binding transcription factor activity
HJH97_01950	COG1105	Belongs to the carbohydrate kinase PfkB family
HJH97_01955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJH97_01955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HJH97_01955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HJH97_01960	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HJH97_01965	COG1253	flavin adenine dinucleotide binding
HJH97_01970	COG0656	L-ascorbic acid biosynthetic process
HJH97_01975	COG0463	Glycosyl transferase, family 2
HJH97_01980	COG5002	protein histidine kinase activity
HJH97_01985	COG0745	RESPONSE REGULATOR receiver
HJH97_02010	COG0602	queuosine metabolic process
HJH97_02015	COG0720	synthase
HJH97_02020	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HJH97_02030	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HJH97_02045	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HJH97_02055	COG1368	sulfuric ester hydrolase activity
HJH97_02075	COG0488	(ABC) transporter
HJH97_02080	COG0514	ATP-dependent DNA helicase (RecQ)
HJH97_02090	COG1174	glycine betaine transport
HJH97_02095	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HJH97_02100	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
HJH97_02105	COG1454	alcohol dehydrogenase
HJH97_02105	COG1012	belongs to the aldehyde dehydrogenase family
HJH97_02110	COG1597	lipid kinase activity
HJH97_02120	COG3104	oligopeptide transport
HJH97_02125	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HJH97_02135	COG1780	Probably involved in ribonucleotide reductase function
HJH97_02140	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HJH97_02145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HJH97_02155	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HJH97_02160	COG4605	iron ion homeostasis
HJH97_02165	COG4604	ABC transporter, ATP-binding protein
HJH97_02180	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HJH97_02200	COG1929	Belongs to the glycerate kinase type-1 family
HJH97_02205	COG2195	Cleaves the N-terminal amino acid of tripeptides
HJH97_02220	COG2199	diguanylate cyclase activity
HJH97_02225	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HJH97_02230	COG1739	Uncharacterized protein family UPF0029
HJH97_02240	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HJH97_02245	COG1040	competence protein
HJH97_02250	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HJH97_02255	COG0653	protein targeting
HJH97_02265	COG3942	CHAP domain
HJH97_02265	COG1388	LysM domain
HJH97_02280	COG0556	nucleotide-excision repair
HJH97_02285	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HJH97_02290	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HJH97_02295	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HJH97_02310	COG0492	ferredoxin-NADP+ reductase activity
HJH97_02315	COG1660	Displays ATPase and GTPase activities
HJH97_02320	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HJH97_02325	COG1481	regulation of sporulation
HJH97_02335	COG0740	serine-type endopeptidase activity
HJH97_02345	COG1090	epimerase
HJH97_02365	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HJH97_02370	COG0126	phosphoglycerate kinase activity
HJH97_02375	COG0149	triose-phosphate isomerase activity
HJH97_02380	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HJH97_02385	COG0148	phosphopyruvate hydratase activity
HJH97_02395	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HJH97_02400	COG1647	Serine aminopeptidase, S33
HJH97_02405	COG0557	exoribonuclease II activity
HJH97_02410	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HJH97_02450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HJH97_02500	COG1278	Cold shock
HJH97_02515	COG4195	phage-related replication protein
HJH97_02570	COG1764	response to oxidative stress
HJH97_02575	COG0710	3-dehydroquinate dehydratase activity
HJH97_02585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HJH97_02590	COG1393	Belongs to the ArsC family
HJH97_02595	COG0509	glycine decarboxylation via glycine cleavage system
HJH97_02600	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HJH97_02610	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HJH97_02615	COG2011	ABC-type metal ion transport system permease component
HJH97_02620	COG1464	Belongs to the NlpA lipoprotein family
HJH97_02630	COG3237	CsbD-like
HJH97_02640	COG0396	ATPase activity
HJH97_02645	COG0719	Fe-S assembly protein
HJH97_02650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HJH97_02655	COG0822	iron-sulfur transferase activity
HJH97_02660	COG0719	Fe-S assembly protein
HJH97_02675	COG1253	flavin adenine dinucleotide binding
HJH97_02680	COG1801	Protein of unknown function DUF72
HJH97_02685	COG0730	response to heat
HJH97_02690	COG0737	Belongs to the 5'-nucleotidase family
HJH97_02695	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HJH97_02700	COG4470	Protein conserved in bacteria
HJH97_02710	COG2445	Protein of unknown function DUF86
HJH97_02715	COG0647	UMP catabolic process
HJH97_02720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HJH97_02730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HJH97_02735	COG1696	Membrane protein involved in D-alanine export
HJH97_02740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HJH97_02745	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HJH97_02750	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HJH97_02755	COG4837	Protein of unknown function (DUF1462)
HJH97_02760	COG1252	NADH dehydrogenase
HJH97_02765	COG4844	belongs to the
HJH97_02770	COG0316	Belongs to the HesB IscA family
HJH97_02775	COG1252	NADH dehydrogenase
HJH97_02780	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HJH97_02785	COG2056	Na+-H+ antiporter family
HJH97_02790	COG2050	protein possibly involved in aromatic compounds catabolism
HJH97_02800	COG1320	monovalent cation:proton antiporter activity
HJH97_02805	COG2212	antiporter activity
HJH97_02810	COG1863	multisubunit Na H antiporter MnhE subunit
HJH97_02815	COG0651	ATP synthesis coupled electron transport
HJH97_02820	COG1006	Multisubunit Na H antiporter MnhC subunit
HJH97_02825	COG2111	Na H antiporter
HJH97_02830	COG2111	Na H antiporter
HJH97_02830	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HJH97_02840	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HJH97_02845	COG1098	S1 RNA binding domain
HJH97_02850	COG1902	pentaerythritol trinitrate reductase activity
HJH97_02865	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HJH97_02875	COG0584	glycerophosphoryl diester phosphodiesterase
HJH97_02880	COG0165	Argininosuccinate lyase
HJH97_02885	COG0137	argininosuccinate synthase activity
HJH97_02890	COG0166	Belongs to the GPI family
HJH97_02895	COG0398	Pfam SNARE associated Golgi protein
HJH97_02910	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HJH97_02915	COG1074	ATP-dependent DNA helicase activity
HJH97_02920	COG0179	Fumarylacetoacetate (FAA) hydrolase
HJH97_02930	COG0446	pyridine nucleotide-disulphide oxidoreductase
HJH97_02935	COG0561	phosphatase activity
HJH97_02950	COG0542	response to heat
HJH97_02965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HJH97_02980	COG0601	transmembrane transport
HJH97_02985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HJH97_02990	COG0444	Belongs to the ABC transporter superfamily
HJH97_02995	COG4608	Belongs to the ABC transporter superfamily
HJH97_03000	COG4166	transmembrane transport
HJH97_03005	COG0180	Tryptophanyl-tRNA synthetase
HJH97_03010	COG1393	Belongs to the ArsC family
HJH97_03020	COG4862	establishment of competence for transformation
HJH97_03030	COG1164	Oligoendopeptidase f
HJH97_03035	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HJH97_03040	COG2346	COG2346, Truncated hemoglobins
HJH97_03055	COG2357	RelA SpoT domain protein
HJH97_03060	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HJH97_03065	COG0564	pseudouridine synthase activity
HJH97_03070	COG2239	Acts as a magnesium transporter
HJH97_03075	COG0475	glutathione-regulated potassium exporter activity
HJH97_03075	COG0569	domain protein
HJH97_03130	COG0628	permease
HJH97_03135	COG2382	esterase
HJH97_03140	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HJH97_03145	COG2814	Major facilitator Superfamily
HJH97_03150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HJH97_03155	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HJH97_03165	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HJH97_03170	COG0861	Integral membrane protein TerC family
HJH97_03175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HJH97_03180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HJH97_03185	COG0737	Belongs to the 5'-nucleotidase family
HJH97_03195	COG4873	Protein conserved in bacteria
HJH97_03250	COG2314	TM2 domain
HJH97_03255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HJH97_03260	COG1575	Belongs to the MenA family. Type 1 subfamily
HJH97_03265	COG1169	isochorismate synthase
HJH97_03270	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HJH97_03280	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HJH97_03285	COG0436	Aminotransferase
HJH97_03290	COG3594	Acyltransferase
HJH97_03320	COG1316	TRANSCRIPTIONal
HJH97_03335	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HJH97_03340	COG1845	cytochrome c oxidase, subunit III
HJH97_03345	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HJH97_03350	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HJH97_03360	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HJH97_03365	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HJH97_03370	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HJH97_03375	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HJH97_03380	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HJH97_03385	COG0047	phosphoribosylformylglycinamidine synthase activity
HJH97_03390	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HJH97_03395	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HJH97_03400	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HJH97_03405	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HJH97_03410	COG0138	bifunctional purine biosynthesis protein purh
HJH97_03415	COG0151	Belongs to the GarS family
HJH97_03420	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HJH97_03425	COG4172	Belongs to the ABC transporter superfamily
HJH97_03435	COG4716	Myosin-crossreactive antigen
HJH97_03445	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HJH97_03455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJH97_03460	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HJH97_03470	COG1271	oxidase subunit
HJH97_03475	COG1294	oxidase, subunit
HJH97_03480	COG0569	domain protein
HJH97_03485	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HJH97_03490	COG5503	Protein of unknown function (DUF1447)
HJH97_03495	COG0242	peptide deformylase activity
HJH97_03505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HJH97_03510	COG0022	dehydrogenase e1 component
HJH97_03515	COG0508	dehydrogenase complex catalyzes the overall conversion of
HJH97_03525	COG4476	Belongs to the UPF0223 family
HJH97_03540	COG3842	ATPase activity
HJH97_03545	COG1176	ABC-type spermidine putrescine transport system, permease component I
HJH97_03570	COG1914	H( )-stimulated, divalent metal cation uptake system
HJH97_03575	COG4493	Belongs to the UPF0637 family
HJH97_03580	COG0483	inositol monophosphate 1-phosphatase activity
HJH97_03590	COG1217	gtp-binding protein TYPA
HJH97_03605	COG4896	Protein conserved in bacteria
HJH97_03610	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HJH97_03615	COG4838	Belongs to the UPF0358 family
HJH97_03620	COG0772	Belongs to the SEDS family
HJH97_03630	COG1612	heme a metabolic process
HJH97_03635	COG0109	protoheme IX farnesyltransferase activity
HJH97_03645	COG2340	Cysteine-rich secretory protein family
HJH97_03650	COG3679	Belongs to the UPF0342 family
HJH97_03655	COG0584	glycerophosphoryl diester phosphodiesterase
HJH97_03660	COG4471	UPF0298 protein
HJH97_03670	COG0742	ribosomal rna small subunit methyltransferase
HJH97_03675	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HJH97_03680	COG1323	Belongs to the UPF0348 family
HJH97_03690	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HJH97_03700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HJH97_03705	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HJH97_03710	COG0072	phenylalanine-tRNA ligase activity
HJH97_03710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HJH97_03715	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HJH97_03720	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HJH97_03730	COG1796	DNA polymerase
HJH97_03730	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HJH97_03735	COG1193	negative regulation of DNA recombination
HJH97_03740	COG3118	belongs to the thioredoxin family
HJH97_03745	COG0322	excinuclease ABC activity
HJH97_03750	COG2009	succinate dehydrogenase
HJH97_03755	COG1053	succinate dehydrogenase
HJH97_03760	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HJH97_03765	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HJH97_03770	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HJH97_03815	COG1011	Hydrolase
HJH97_03820	COG0454	-acetyltransferase
HJH97_03825	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HJH97_03830	COG2001	Belongs to the MraZ family
HJH97_03835	COG0275	rRNA processing
HJH97_03840	COG4839	cell division protein FtsL
HJH97_03845	COG0768	penicillin binding
HJH97_03850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HJH97_03855	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HJH97_03860	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HJH97_03865	COG0849	cell division
HJH97_03870	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HJH97_03875	COG1496	oxidoreductase activity
HJH97_03880	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HJH97_03885	COG1799	cell septum assembly
HJH97_03890	COG0762	integral membrane protein
HJH97_03900	COG3599	regulation of cell shape
HJH97_03905	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HJH97_03915	COG1388	LysM domain
HJH97_03915	COG3942	CHAP domain
HJH97_03920	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HJH97_03925	COG0564	pseudouridine synthase activity
HJH97_03930	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HJH97_03935	COG2233	PERMEase
HJH97_03940	COG0540	Belongs to the ATCase OTCase family
HJH97_03945	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HJH97_03950	COG0505	Belongs to the CarA family
HJH97_03955	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HJH97_03960	COG0284	orotidine-5'-phosphate decarboxylase activity
HJH97_03965	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HJH97_03985	COG0194	GDP metabolic process
HJH97_03990	COG1758	RNA polymerase activity
HJH97_03995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HJH97_04000	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HJH97_04010	COG0242	peptide deformylase activity
HJH97_04015	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HJH97_04020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HJH97_04020	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HJH97_04025	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HJH97_04030	COG0631	protein serine/threonine phosphatase activity
HJH97_04040	COG1162	GTPase activity
HJH97_04045	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HJH97_04055	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HJH97_04060	COG1302	Protein conserved in bacteria
HJH97_04065	COG1461	Dihydroxyacetone kinase
HJH97_04070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HJH97_04075	COG1349	DNA-binding transcription factor activity
HJH97_04080	COG0416	fatty acid biosynthetic process
HJH97_04090	COG1028	Short-chain dehydrogenase reductase Sdr
HJH97_04095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HJH97_04100	COG0571	ribonuclease III activity
HJH97_04105	COG1196	nuclear chromosome segregation
HJH97_04110	COG0552	protein localization to endoplasmic reticulum
HJH97_04115	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HJH97_04120	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HJH97_04125	COG0228	four-way junction DNA binding
HJH97_04130	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HJH97_04135	COG0336	Belongs to the RNA methyltransferase TrmD family
HJH97_04140	COG0335	large ribosomal subunit rRNA binding
HJH97_04150	COG4485	Bacterial membrane protein, YfhO
HJH97_04160	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HJH97_04165	COG0045	succinate-CoA ligase (ADP-forming) activity
HJH97_04170	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HJH97_04175	COG0758	DNA mediated transformation
HJH97_04180	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HJH97_04185	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HJH97_04190	COG4974	Belongs to the 'phage' integrase family
HJH97_04195	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HJH97_04200	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HJH97_04205	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HJH97_04210	COG0052	Belongs to the universal ribosomal protein uS2 family
HJH97_04215	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HJH97_04220	COG0528	UMP kinase activity
HJH97_04225	COG0233	cytoplasmic translational termination
HJH97_04230	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HJH97_04235	COG4589	Belongs to the CDS family
HJH97_04245	COG0442	prolyl-tRNA aminoacylation
HJH97_04250	COG2176	DNA-directed DNA polymerase activity
HJH97_04255	COG0779	Required for maturation of 30S ribosomal subunits
HJH97_04260	COG0195	Participates in both transcription termination and antitermination
HJH97_04265	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HJH97_04270	COG1358	cellular component organization or biogenesis
HJH97_04275	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HJH97_04280	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HJH97_04285	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HJH97_04290	COG0196	riboflavin kinase activity
HJH97_04295	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HJH97_04300	COG1185	polyribonucleotide nucleotidyltransferase activity
HJH97_04305	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HJH97_04310	COG1674	ftsk spoiiie
HJH97_04315	COG2188	Transcriptional regulator
HJH97_04320	COG0612	Peptidase, M16
HJH97_04325	COG0612	Peptidase, M16
HJH97_04330	COG0300	oxidoreductase activity
HJH97_04345	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HJH97_04355	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HJH97_04360	COG1418	mRNA catabolic process
HJH97_04370	COG1692	metallophosphoesterase
HJH97_04375	COG0674	pyruvate-flavodoxin oxidoreductase activity
HJH97_04375	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HJH97_04380	COG1013	pyruvate-flavodoxin oxidoreductase activity
HJH97_04385	COG4195	phage-related replication protein
HJH97_04395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HJH97_04400	COG4550	Control of competence regulator ComK, YlbF/YmcA
HJH97_04410	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HJH97_04415	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HJH97_04420	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HJH97_04425	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HJH97_04430	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HJH97_04435	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HJH97_04445	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HJH97_04450	COG1923	regulation of RNA biosynthetic process
HJH97_04455	COG0386	Belongs to the glutathione peroxidase family
HJH97_04460	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HJH97_04465	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
HJH97_04470	COG0789	Transcriptional regulator
HJH97_04475	COG0174	glutamine synthetase
HJH97_04520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HJH97_04525	COG1131	(ABC) transporter
HJH97_04535	COG4585	Histidine kinase
HJH97_04540	COG2197	response regulator
HJH97_04550	COG1525	nuclease
HJH97_04575	COG0527	aspartate kinase activity
HJH97_04580	COG0460	homoserine dehydrogenase
HJH97_04585	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HJH97_04590	COG0083	homoserine kinase activity
HJH97_04605	COG0833	amino acid
HJH97_04610	COG0753	catalase activity
HJH97_04620	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HJH97_04625	COG0516	GMP reductase activity
HJH97_04630	COG2340	Cysteine-rich secretory protein family
HJH97_04635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HJH97_04645	COG4224	UPF0291 protein
HJH97_04650	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HJH97_04660	COG4846	Membrane protein involved in cytochrome C biogenesis
HJH97_04665	COG0420	3'-5' exonuclease activity
HJH97_04670	COG0419	ATPase involved in DNA repair
HJH97_04675	COG1970	mechanosensitive ion channel activity
HJH97_04680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HJH97_04685	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HJH97_04690	COG0824	Thioesterase
HJH97_04695	COG4841	protein insertion into membrane
HJH97_04700	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HJH97_04705	COG0187	DNA topoisomerase II activity
HJH97_04710	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HJH97_04715	COG1115	amino acid carrier protein
HJH97_04720	COG3711	transcriptional antiterminator
HJH97_04725	COG0628	permease
HJH97_04730	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HJH97_04730	COG0392	lysyltransferase activity
HJH97_04750	COG1942	4-Oxalocrotonate Tautomerase
HJH97_04755	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HJH97_04760	COG0287	Prephenate dehydrogenase
HJH97_04765	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HJH97_04770	COG0512	Glutamine amidotransferase of anthranilate synthase
HJH97_04770	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HJH97_04775	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HJH97_04780	COG0134	indole-3-glycerol-phosphate synthase activity
HJH97_04785	COG0135	phosphoribosylanthranilate isomerase activity
HJH97_04790	COG0133	tryptophan synthase activity
HJH97_04795	COG0159	tryptophan synthase activity
HJH97_04805	COG2348	transferase activity, transferring amino-acyl groups
HJH97_04810	COG2348	transferase activity, transferring amino-acyl groups
HJH97_04850	COG0704	Plays a role in the regulation of phosphate uptake
HJH97_04855	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HJH97_04860	COG0581	inorganic phosphate transmembrane transporter activity
HJH97_04865	COG0573	inorganic phosphate transmembrane transporter activity
HJH97_04870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HJH97_04875	COG2996	Protein conserved in bacteria
HJH97_04880	COG0488	(ABC) transporter
HJH97_04885	COG0527	aspartate kinase activity
HJH97_04890	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HJH97_04895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HJH97_04900	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HJH97_04905	COG2171	N-acyltransferase activity
HJH97_04910	COG1473	amidohydrolase
HJH97_04930	COG1131	(ABC) transporter
HJH97_04945	COG1278	Cold shock
HJH97_04955	COG1254	Belongs to the acylphosphatase family
HJH97_04965	COG3853	Toxic anion resistance protein (TelA)
HJH97_04970	COG1114	Component of the transport system for branched-chain amino acids
HJH97_04975	COG4548	von Willebrand factor, type A
HJH97_04980	COG0714	Associated with various cellular activities
HJH97_05000	COG0508	dehydrogenase complex catalyzes the overall conversion of
HJH97_05005	COG0567	Dehydrogenase, E1 component
HJH97_05010	COG5002	protein histidine kinase activity
HJH97_05015	COG0745	RESPONSE REGULATOR receiver
HJH97_05020	COG1349	DNA-binding transcription factor activity
HJH97_05025	COG0534	Mate efflux family protein
HJH97_05035	COG0395	ABC-type sugar transport system, permease component
HJH97_05045	COG4209	transmembrane transport
HJH97_05050	COG3842	ATPase activity
HJH97_05055	COG0671	phosphoesterase, PA-phosphatase related
HJH97_05060	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HJH97_05070	COG0793	Belongs to the peptidase S41A family
HJH97_05075	COG4479	Belongs to the UPF0346 family
HJH97_05080	COG2190	(PTS) system
HJH97_05085	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HJH97_05110	COG1136	(ABC) transporter
HJH97_05125	COG1413	lyase activity
HJH97_05135	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HJH97_05150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HJH97_05155	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HJH97_05165	COG0116	Belongs to the methyltransferase superfamily
HJH97_05175	COG3599	regulation of cell shape
HJH97_05180	COG4474	Belongs to the UPF0398 family
HJH97_05190	COG3331	DNA recombination
HJH97_05195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HJH97_05195	COG4499	WXG100 protein secretion system (Wss), protein YukC
HJH97_05205	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HJH97_05210	COG3935	DnaD domain protein
HJH97_05215	COG0017	Asparaginyl-tRNA synthetase
HJH97_05220	COG1199	ATP-dependent helicase activity
HJH97_05220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HJH97_05225	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HJH97_05225	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HJH97_05230	COG0617	tRNA 3'-terminal CCA addition
HJH97_05235	COG0438	transferase activity, transferring glycosyl groups
HJH97_05240	COG1694	Mazg nucleotide pyrophosphohydrolase
HJH97_05245	COG2738	Putative neutral zinc metallopeptidase
HJH97_05250	COG4347	Protein of unknown function (DUF1405)
HJH97_05255	COG5582	Belongs to the UPF0302 family
HJH97_05265	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HJH97_05270	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HJH97_05275	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HJH97_05280	COG0105	UTP biosynthetic process
HJH97_05290	COG2226	methyltransferase
HJH97_05305	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HJH97_05310	COG1160	GTP binding
HJH97_05315	COG0539	negative regulation of cytoplasmic translation
HJH97_05320	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HJH97_05325	COG0252	asparaginase activity
HJH97_05330	COG0492	ferredoxin-NADP+ reductase activity
HJH97_05335	COG1388	LysM domain
HJH97_05340	COG0514	ATP-dependent DNA helicase (RecQ)
HJH97_05350	COG1141	Ferredoxin
HJH97_05365	COG0745	RESPONSE REGULATOR receiver
HJH97_05370	COG1187	pseudouridine synthase activity
HJH97_05375	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HJH97_05380	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HJH97_05385	COG1547	Domain of unknown function (DUF309)
HJH97_05390	COG4974	Belongs to the 'phage' integrase family
HJH97_05395	COG0735	belongs to the Fur family
HJH97_05400	COG0494	nUDIX hydrolase
HJH97_05405	COG0667	Aldo Keto reductase
HJH97_05410	COG1028	Short-chain dehydrogenase reductase Sdr
HJH97_05415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HJH97_05420	COG1234	tRNA 3'-trailer cleavage
HJH97_05425	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HJH97_05435	COG0366	Alpha amylase catalytic
HJH97_05440	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HJH97_05445	COG2195	Cleaves the N-terminal amino acid of tripeptides
HJH97_05455	COG4129	membrane
HJH97_05465	COG0508	dehydrogenase complex catalyzes the overall conversion of
HJH97_05470	COG0022	dehydrogenase e1 component
HJH97_05475	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HJH97_05480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HJH97_05485	COG0497	DNA recombination
HJH97_05490	COG1438	arginine binding
HJH97_05500	COG1722	exodeoxyribonuclease VII activity
HJH97_05505	COG1570	exodeoxyribonuclease VII activity
HJH97_05510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HJH97_05515	COG1302	Protein conserved in bacteria
HJH97_05520	COG0439	Biotin carboxylase
HJH97_05525	COG0511	ligase activity, forming carbon-carbon bonds
HJH97_05530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HJH97_05535	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HJH97_05540	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HJH97_05545	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HJH97_05550	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HJH97_05555	COG0006	proline dipeptidase activity
HJH97_05575	COG0095	Lipoate-protein ligase
HJH97_05580	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HJH97_05590	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HJH97_05595	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HJH97_05600	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HJH97_05605	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HJH97_05625	COG4537	Required for transformation and DNA binding
HJH97_05630	COG1459	type II secretion system
HJH97_05635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HJH97_05645	COG0011	TIGRFAM Protein of
HJH97_05650	COG1940	carbohydrate kinase activity
HJH97_05655	COG4483	Protein conserved in bacteria
HJH97_05665	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HJH97_05670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HJH97_05675	COG0768	penicillin binding
HJH97_05680	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HJH97_05685	COG0735	belongs to the Fur family
HJH97_05690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HJH97_05695	COG1121	(ABC) transporter
HJH97_05700	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HJH97_05705	COG0513	Belongs to the DEAD box helicase family
HJH97_05710	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HJH97_05715	COG2384	SAM-dependent methyltransferase
HJH97_05720	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HJH97_05725	COG0358	DNA primase activity
HJH97_05730	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
HJH97_05735	COG0517	IMP dehydrogenase activity
HJH97_05740	COG0423	glycine-tRNA ligase activity
HJH97_05745	COG1381	Involved in DNA repair and RecF pathway recombination
HJH97_05750	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HJH97_05760	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HJH97_05765	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HJH97_05770	COG1702	phosphate starvation-inducible protein PhoH
HJH97_05780	COG4864	UPF0365 protein
HJH97_05785	COG1030	water channel activity
HJH97_05795	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HJH97_05800	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HJH97_05805	COG2264	protein methyltransferase activity
HJH97_05810	COG0484	heat shock protein binding
HJH97_05815	COG0443	Heat shock 70 kDa protein
HJH97_05820	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HJH97_05825	COG1420	regulation of RNA biosynthetic process
HJH97_05830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HJH97_05835	COG0481	GTPase activity
HJH97_05840	COG0268	Binds directly to 16S ribosomal RNA
HJH97_05845	COG1466	dna polymerase III delta subunit
HJH97_05850	COG2333	competence protein COMEC
HJH97_05850	COG0658	competence protein
HJH97_05855	COG2131	deaminase
HJH97_05865	COG2226	methyltransferase
HJH97_05870	COG0799	negative regulation of ribosome biogenesis
HJH97_05875	COG1713	HD superfamily hydrolase involved in NAD metabolism
HJH97_05880	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HJH97_05885	COG1534	Rna-binding protein
HJH97_05890	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HJH97_05895	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HJH97_05900	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HJH97_05905	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HJH97_05910	COG1914	H( )-stimulated, divalent metal cation uptake system
HJH97_05915	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
HJH97_05920	COG0439	Biotin carboxylase
HJH97_05925	COG0511	ligase activity, forming carbon-carbon bonds
HJH97_05930	COG1984	allophanate hydrolase subunit 2
HJH97_05935	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HJH97_05945	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HJH97_05950	COG0572	uridine kinase
HJH97_05955	COG0826	peptidase U32
HJH97_05960	COG0826	peptidase U32
HJH97_05970	COG3906	Belongs to the UPF0473 family
HJH97_05975	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HJH97_05980	COG4472	Bacterial protein of unknown function (DUF965)
HJH97_05985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HJH97_05990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HJH97_06000	COG0482	sulfurtransferase activity
HJH97_06005	COG1104	cysteine desulfurase activity
HJH97_06010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HJH97_06020	COG1959	2 iron, 2 sulfur cluster binding
HJH97_06025	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HJH97_06030	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HJH97_06040	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HJH97_06045	COG0124	histidyl-tRNA synthetase
HJH97_06050	COG0860	N-Acetylmuramoyl-L-alanine amidase
HJH97_06055	COG1490	D-aminoacyl-tRNA deacylase activity
HJH97_06060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HJH97_06065	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HJH97_06070	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HJH97_06070	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HJH97_06080	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HJH97_06080	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HJH97_06085	COG1862	Preprotein translocase
HJH97_06090	COG0343	queuine tRNA-ribosyltransferase activity
HJH97_06095	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HJH97_06100	COG2255	four-way junction helicase activity
HJH97_06105	COG0632	four-way junction helicase activity
HJH97_06110	COG4492	Belongs to the UPF0735 family
HJH97_06115	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HJH97_06120	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HJH97_06125	COG2868	ribosomal protein
HJH97_06130	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HJH97_06160	COG2003	Belongs to the UPF0758 family
HJH97_06170	COG0285	dihydrofolate synthase activity
HJH97_06175	COG0525	valine-tRNA ligase activity
HJH97_06180	COG2818	Glycosylase
HJH97_06190	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HJH97_06195	COG0113	porphobilinogen synthase activity
HJH97_06205	COG0181	hydroxymethylbilane synthase activity
HJH97_06215	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HJH97_06220	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HJH97_06225	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HJH97_06230	COG0544	peptidyl-prolyl cis-trans isomerase activity
HJH97_06240	COG4112	unkown
HJH97_06245	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HJH97_06250	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HJH97_06255	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HJH97_06260	COG0833	amino acid
HJH97_06265	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HJH97_06270	COG1484	DNA-dependent DNA replication
HJH97_06275	COG3611	Membrane attachment protein
HJH97_06280	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HJH97_06290	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HJH97_06300	COG0237	dephospho-CoA kinase activity
HJH97_06305	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HJH97_06310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HJH97_06310	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HJH97_06315	COG5002	protein histidine kinase activity
HJH97_06320	COG0745	RESPONSE REGULATOR receiver
HJH97_06325	COG0538	isocitrate dehydrogenase activity
HJH97_06330	COG0372	Belongs to the citrate synthase family
HJH97_06335	COG1113	amino acid transport
HJH97_06340	COG0469	pyruvate kinase activity
HJH97_06345	COG0205	6-phosphofructokinase activity
HJH97_06350	COG0825	malonyl-CoA metabolic process
HJH97_06355	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HJH97_06360	COG0281	malic enzyme
HJH97_06365	COG0587	DNA-directed DNA polymerase activity
HJH97_06370	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HJH97_06375	COG4109	DRTGG domain
HJH97_06385	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HJH97_06390	COG0006	proline dipeptidase activity
HJH97_06395	COG0686	Belongs to the AlaDH PNT family
HJH97_06400	COG0589	response to stress
HJH97_06405	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HJH97_06410	COG0827	DNA restriction-modification system
HJH97_06415	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HJH97_06425	COG0301	tRNA thio-modification
HJH97_06435	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HJH97_06440	COG1956	GAF domain-containing protein
HJH97_06445	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HJH97_06450	COG0584	glycerophosphoryl diester phosphodiesterase
HJH97_06455	COG1764	response to oxidative stress
HJH97_06460	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HJH97_06465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HJH97_06475	COG1263	PTS System
HJH97_06475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HJH97_06480	COG0204	Acyl-transferase
HJH97_06485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HJH97_06490	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HJH97_06500	COG2759	Belongs to the formate--tetrahydrofolate ligase family
HJH97_06505	COG1609	Transcriptional regulator
HJH97_06510	COG1605	Chorismate mutase
HJH97_06510	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HJH97_06525	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HJH97_06530	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HJH97_06535	COG1674	ftsk spoiiie
HJH97_06540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HJH97_06545	COG4848	Belongs to the UPF0354 family
HJH97_06550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HJH97_06555	COG1363	Peptidase, m42
HJH97_06565	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HJH97_06570	COG0510	thiamine kinase activity
HJH97_06575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HJH97_06580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HJH97_06590	COG1187	pseudouridine synthase activity
HJH97_06595	COG2244	polysaccharide biosynthetic process
HJH97_06600	COG2081	HI0933 family
HJH97_06615	COG0495	leucyl-tRNA aminoacylation
HJH97_06620	COG2814	Major facilitator Superfamily
HJH97_06625	COG1242	4 iron, 4 sulfur cluster binding
HJH97_06630	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HJH97_06640	COG2267	carboxylic ester hydrolase activity
HJH97_06645	COG0506	proline dehydrogenase activity
HJH97_06650	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HJH97_06655	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HJH97_06655	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HJH97_06665	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HJH97_06665	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HJH97_06675	COG4193	domain, Protein
HJH97_06675	COG3266	domain, Protein
HJH97_06675	COG5632	N-Acetylmuramoyl-L-alanine amidase
HJH97_06700	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HJH97_06710	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HJH97_06715	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HJH97_06730	COG0656	L-ascorbic acid biosynthetic process
HJH97_06740	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HJH97_06745	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HJH97_06750	COG1506	peptidase
HJH97_06755	COG0494	nUDIX hydrolase
HJH97_06760	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HJH97_06770	COG0318	PFAM AMP-dependent synthetase and ligase
HJH97_06845	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HJH97_06850	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HJH97_06855	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HJH97_06860	COG2329	Antibiotic biosynthesis monooxygenase
HJH97_06870	COG4473	ABC transporter
HJH97_06875	COG1131	(ABC) transporter
HJH97_06880	COG0537	adenosine 5'-monophosphoramidase activity
HJH97_06895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HJH97_06905	COG3481	metal-dependent phosphohydrolase, HD sub domain
HJH97_06915	COG0420	3'-5' exonuclease activity
HJH97_06920	COG3679	Belongs to the UPF0342 family
HJH97_06925	COG4399	Belongs to the UPF0754 family
HJH97_06935	COG2197	response regulator
HJH97_06940	COG2203	Gaf domain
HJH97_06940	COG4585	Histidine kinase
HJH97_06945	COG0564	pseudouridine synthase activity
HJH97_06950	COG0114	fumarate hydratase activity
HJH97_06975	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HJH97_06985	COG1126	abc transporter atp-binding protein
HJH97_06990	COG0765	amino acid transport
HJH97_07160	COG0735	belongs to the Fur family
HJH97_07165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HJH97_07170	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HJH97_07175	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HJH97_07180	COG4129	membrane
HJH97_07190	COG3557	Belongs to the UPF0374 family
HJH97_07200	COG1988	membrane-bound metal-dependent
HJH97_07210	COG1134	teichoic acid transport
HJH97_07210	COG1388	LysM domain
HJH97_07220	COG2137	regulation of response to DNA damage stimulus
HJH97_07225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HJH97_07230	COG0693	protein deglycase activity
HJH97_07240	COG0535	radical SAM domain protein
HJH97_07245	COG1607	acyl-coa hydrolase
HJH97_07250	COG2309	aminopeptidase activity
HJH97_07255	COG4840	Belongs to the UPF0435 family
HJH97_07260	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HJH97_07270	COG1295	ribonuclease BN
HJH97_07275	COG2197	response regulator
HJH97_07280	COG4585	Histidine kinase
HJH97_07295	COG0024	Methionine aminopeptidase
HJH97_07300	COG4129	membrane
HJH97_07320	COG1528	Iron-storage protein
HJH97_07330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HJH97_07340	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HJH97_07345	COG1597	lipid kinase activity
HJH97_07350	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HJH97_07355	COG0154	amidase activity
HJH97_07360	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HJH97_07365	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HJH97_07370	COG4851	CamS sex pheromone cAM373 precursor
HJH97_07375	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HJH97_07380	COG0210	DNA helicase
HJH97_07385	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HJH97_07390	COG4496	protein, YerC YecD
HJH97_07395	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HJH97_07405	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
HJH97_07410	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HJH97_07415	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HJH97_07425	COG0077	Prephenate dehydratase
HJH97_07435	COG1335	isochorismatase
HJH97_07440	COG1227	inorganic diphosphatase activity
HJH97_07445	COG1012	belongs to the aldehyde dehydrogenase family
HJH97_07450	COG2706	6-phosphogluconolactonase activity
HJH97_07455	COG3682	Transcriptional regulator
HJH97_07535	COG1131	(ABC) transporter
HJH97_07545	COG1131	(ABC) transporter
HJH97_07550	COG1725	Transcriptional regulator
HJH97_07570	COG0459	protein refolding
HJH97_07575	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HJH97_07610	COG3290	protein histidine kinase activity
HJH97_07615	COG3279	Response regulator of the LytR AlgR family
HJH97_07620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HJH97_07625	COG1621	beta-fructofuranosidase activity
HJH97_07630	COG1609	Transcriptional regulator
HJH97_07635	COG0004	ammonium transporteR
HJH97_07640	COG0425	Belongs to the sulfur carrier protein TusA family
HJH97_07645	COG2391	methyltransferase activity
HJH97_07655	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HJH97_07660	COG0488	(ABC) transporter
HJH97_07665	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HJH97_07670	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HJH97_07675	COG0456	acetyltransferase
HJH97_07680	COG1214	PFAM Peptidase M22, glycoprotease
HJH97_07685	COG0802	atpase or kinase
HJH97_07690	COG0129	dihydroxy-acid dehydratase activity
HJH97_07695	COG0028	Belongs to the TPP enzyme family
HJH97_07705	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HJH97_07710	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HJH97_07715	COG0473	3-isopropylmalate dehydrogenase activity
HJH97_07720	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HJH97_07725	COG0066	3-isopropylmalate dehydratase activity
HJH97_07730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HJH97_07760	COG3091	SprT-like family
HJH97_07765	COG2183	response to ionizing radiation
HJH97_07770	COG1191	sigma factor activity
HJH97_07785	COG2208	phosphoserine phosphatase activity
HJH97_07790	COG2337	Toxic component of a toxin-antitoxin (TA) module
HJH97_07800	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HJH97_07805	COG0736	holo-[acyl-carrier-protein] synthase activity
HJH97_07810	COG3402	PFAM membrane-flanked domain
HJH97_07815	COG3428	Bacterial PH domain
HJH97_07825	COG0513	Belongs to the DEAD box helicase family
HJH97_07830	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HJH97_07835	COG1181	Belongs to the D-alanine--D-alanine ligase family
HJH97_07840	COG0772	Belongs to the SEDS family
HJH97_07855	COG1937	Protein conserved in bacteria
HJH97_07860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HJH97_07865	COG1418	mRNA catabolic process
HJH97_07870	COG0706	membrane insertase activity
HJH97_07875	COG0352	thiamine-phosphate diphosphorylase activity
HJH97_07880	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HJH97_07890	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HJH97_07895	COG1388	LysM domain
HJH97_07900	COG0629	single-stranded DNA binding
HJH97_07910	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HJH97_07915	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HJH97_07925	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HJH97_07930	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HJH97_07935	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HJH97_07940	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HJH97_07945	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HJH97_07950	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HJH97_07960	COG0356	it plays a direct role in the translocation of protons across the membrane
HJH97_07970	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HJH97_07975	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HJH97_07980	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HJH97_07985	COG4475	Protein of unknown function (DUF436)
HJH97_07990	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HJH97_07995	COG0009	L-threonylcarbamoyladenylate synthase
HJH97_08000	COG2890	protein-(glutamine-N5) methyltransferase activity
HJH97_08005	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HJH97_08010	COG1435	thymidine kinase activity
HJH97_08015	COG0254	rRNA binding
HJH97_08020	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HJH97_08025	COG1012	belongs to the aldehyde dehydrogenase family
HJH97_08030	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HJH97_08035	COG0191	fructose-bisphosphate aldolase activity
HJH97_08045	COG0504	CTP synthase activity
HJH97_08050	COG3343	RNA polymerase activity
HJH97_08060	COG5146	pantothenate kinase activity
HJH97_08080	COG1854	S-ribosylhomocysteine lyase activity
HJH97_08090	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HJH97_08095	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HJH97_08100	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HJH97_08105	COG0813	purine-nucleoside phosphorylase activity
HJH97_08110	COG0783	Belongs to the Dps family
HJH97_08130	COG1482	cell wall glycoprotein biosynthetic process
HJH97_08135	COG0702	epimerase
HJH97_08140	COG0640	Transcriptional regulator
HJH97_08160	COG0561	phosphatase activity
HJH97_08165	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HJH97_08170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HJH97_08180	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HJH97_08230	COG0489	protein tyrosine kinase activity
HJH97_08235	COG2814	Major facilitator Superfamily
HJH97_08255	COG4284	Utp--glucose-1-phosphate uridylyltransferase
HJH97_08260	COG1988	membrane-bound metal-dependent
HJH97_08270	COG2329	Antibiotic biosynthesis monooxygenase
HJH97_08275	COG3314	Sporulation integral membrane protein YlbJ
HJH97_08280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HJH97_08285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HJH97_08290	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HJH97_08295	COG3457	Alanine racemase
HJH97_08300	COG4264	IucA IucC family
HJH97_08305	COG2814	Major facilitator Superfamily
HJH97_08310	COG4264	IucA IucC family
HJH97_08315	COG1302	Protein conserved in bacteria
HJH97_08330	COG0604	alcohol dehydrogenase
HJH97_08335	COG2130	NADP-dependent
HJH97_08340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HJH97_08350	COG2723	6-phospho-beta-galactosidase activity
HJH97_08355	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJH97_08355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJH97_08360	COG1447	Phosphotransferase system cellobiose-specific component IIA
HJH97_08365	COG3684	Belongs to the aldolase LacD family
HJH97_08370	COG1105	Belongs to the carbohydrate kinase PfkB family
HJH97_08375	COG0698	ribose 5-phosphate isomerase
HJH97_08380	COG0698	ribose 5-phosphate isomerase
HJH97_08385	COG1349	DNA-binding transcription factor activity
HJH97_08390	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HJH97_08395	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HJH97_08400	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HJH97_08405	COG0101	tRNA pseudouridine synthase activity
HJH97_08415	COG1122	ATPase activity
HJH97_08420	COG1122	ATPase activity
HJH97_08425	COG0203	ribosomal protein L17
HJH97_08430	COG0202	RNA polymerase activity
HJH97_08435	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HJH97_08440	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HJH97_08445	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HJH97_08450	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HJH97_08455	COG0563	adenylate kinase activity
HJH97_08460	COG0201	protein transport
HJH97_08465	COG0200	Binds to the 23S rRNA
HJH97_08470	COG1841	ribosomal large subunit assembly
HJH97_08475	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HJH97_08480	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HJH97_08485	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HJH97_08490	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HJH97_08495	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HJH97_08500	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HJH97_08505	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HJH97_08510	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HJH97_08515	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HJH97_08525	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HJH97_08530	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HJH97_08535	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HJH97_08540	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HJH97_08545	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HJH97_08550	COG0089	rRNA binding
HJH97_08555	COG0088	Forms part of the polypeptide exit tunnel
HJH97_08560	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HJH97_08575	COG2252	PERMEase
HJH97_08580	COG0551	DNA topoisomerase type I activity
HJH97_08580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HJH97_08585	COG4975	Glucose uptake
HJH97_08590	COG1028	Short-chain dehydrogenase reductase Sdr
HJH97_08610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HJH97_08615	COG2348	transferase activity, transferring amino-acyl groups
HJH97_08650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HJH97_08655	COG0746	molybdenum cofactor guanylyltransferase activity
HJH97_08665	COG0314	molybdopterin synthase activity
HJH97_08675	COG0303	'Molybdopterin
HJH97_08680	COG0315	cyclic pyranopterin monophosphate synthase activity
HJH97_08685	COG0521	Mo-molybdopterin cofactor biosynthetic process
HJH97_08690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HJH97_08695	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HJH97_08700	COG4149	molybdate abc transporter
HJH97_08705	COG0725	ABC transporter, periplasmic molybdate-binding protein
HJH97_08720	COG1268	BioY protein
HJH97_08725	COG1957	nucleoside hydrolase
HJH97_08730	COG1960	acyl-CoA dehydrogenase activity
HJH97_08740	COG0831	urea catabolic process
HJH97_08745	COG0832	Belongs to the urease beta subunit family
HJH97_08750	COG0804	urea catabolic process
HJH97_08755	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HJH97_08760	COG0830	nickel cation binding
HJH97_08765	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HJH97_08770	COG0829	nickel cation binding
HJH97_08795	COG3942	CHAP domain
HJH97_08800	COG1757	Na H antiporter
HJH97_08815	COG3942	CHAP domain
HJH97_08820	COG2076	Multidrug Resistance protein
HJH97_08825	COG2076	Multidrug Resistance protein
HJH97_08830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HJH97_08850	COG1316	TRANSCRIPTIONal
HJH97_08855	COG0483	inositol monophosphate 1-phosphatase activity
HJH97_08860	COG2378	regulation of single-species biofilm formation
HJH97_08865	COG1266	CAAX protease self-immunity
HJH97_08880	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HJH97_08885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HJH97_08885	COG1263	PTS System
HJH97_08895	COG1113	amino acid transport
HJH97_08920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HJH97_08930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HJH97_08930	COG1263	PTS System
HJH97_08935	COG1737	Transcriptional regulator
HJH97_08970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HJH97_08975	COG1028	Short-chain dehydrogenase reductase Sdr
HJH97_08980	COG1473	amidohydrolase
HJH97_08985	COG0010	Belongs to the arginase family
HJH97_08990	COG1266	CAAX protease self-immunity
HJH97_09000	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HJH97_09005	COG2258	MOSC domain
HJH97_09010	COG2017	converts alpha-aldose to the beta-anomer
HJH97_09015	COG1069	ribulokinase activity
HJH97_09025	COG2094	Belongs to the DNA glycosylase MPG family
HJH97_09045	COG0786	glutamate:sodium symporter activity
HJH97_09050	COG1304	FMN binding
HJH97_09055	COG0598	Magnesium transport protein CorA
HJH97_09070	COG0657	acetylesterase activity
HJH97_09080	COG2814	Major facilitator Superfamily
HJH97_09085	COG1566	PFAM secretion protein HlyD family protein
HJH97_09095	COG2814	Major facilitator Superfamily
HJH97_09100	COG4640	response to antibiotic
HJH97_09115	COG1136	(ABC) transporter
HJH97_09120	COG0577	efflux transmembrane transporter activity
HJH97_09125	COG0745	RESPONSE REGULATOR receiver
HJH97_09130	COG3850	Histidine kinase
HJH97_09130	COG5002	protein histidine kinase activity
HJH97_09135	COG0579	oxidoreductase
HJH97_09140	COG0438	transferase activity, transferring glycosyl groups
HJH97_09145	COG1620	l-lactate permease
HJH97_09150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HJH97_09150	COG0463	Glycosyl transferase, family 2
HJH97_09160	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HJH97_09160	COG0463	Glycosyl transferase, family 2
HJH97_09165	COG0456	acetyltransferase
HJH97_09170	COG0604	alcohol dehydrogenase
HJH97_09205	COG1263	PTS System
HJH97_09205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HJH97_09220	COG3871	stress protein (general stress protein 26)
HJH97_09240	COG0778	Nitroreductase
HJH97_09245	COG1846	Transcriptional regulator
HJH97_09250	COG2223	nitrite transmembrane transporter activity
HJH97_09255	COG2197	response regulator
HJH97_09260	COG4585	Histidine kinase
HJH97_09270	COG2181	nitrate reductase activity
HJH97_09280	COG1140	nitrate reductase beta subunit
HJH97_09285	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HJH97_09295	COG2146	nitrite reductase [NAD(P)H] activity
HJH97_09300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HJH97_09310	COG0747	negative chemotaxis
HJH97_09320	COG0454	-acetyltransferase
HJH97_09325	COG2116	formate transmembrane transporter activity
HJH97_09345	COG2348	transferase activity, transferring amino-acyl groups
HJH97_09350	COG1126	abc transporter atp-binding protein
HJH97_09355	COG0765	amino acid transport
HJH97_09360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HJH97_09370	COG0588	phosphoglycerate mutase activity
HJH97_09375	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HJH97_09390	COG1929	Belongs to the glycerate kinase type-1 family
HJH97_09415	COG1113	amino acid transport
HJH97_09420	COG0531	amino acid
HJH97_09430	COG0706	membrane insertase activity
HJH97_09435	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HJH97_09445	COG3275	phosphorelay sensor kinase activity
HJH97_09450	COG3279	Response regulator of the LytR AlgR family
HJH97_09455	COG1380	Effector of murein hydrolase LrgA
HJH97_09460	COG1346	cytolysis
HJH97_09465	COG1174	glycine betaine transport
HJH97_09485	COG1063	alcohol dehydrogenase
HJH97_09495	COG0531	amino acid
HJH97_09500	COG2272	Belongs to the type-B carboxylesterase lipase family
HJH97_09505	COG2814	Major facilitator Superfamily
HJH97_09510	COG0390	transport system, permease component
HJH97_09515	COG4619	ABC transporter
HJH97_09530	COG0069	glutamate synthase activity
HJH97_09540	COG1363	Peptidase, m42
HJH97_09550	COG1028	Short-chain dehydrogenase reductase Sdr
HJH97_09560	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HJH97_09565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HJH97_09570	COG4221	oxidoreductase activity
HJH97_09580	COG0556	nucleotide-excision repair
HJH97_09585	COG0494	nUDIX hydrolase
HJH97_09590	COG0438	transferase activity, transferring glycosyl groups
HJH97_09595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HJH97_09600	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HJH97_09605	COG2610	gluconate transmembrane transporter activity
HJH97_09615	COG1802	Transcriptional regulator
HJH97_09620	COG2271	Major facilitator Superfamily
HJH97_09625	COG0789	Transcriptional regulator
HJH97_09640	COG2357	RelA SpoT domain protein
HJH97_09645	COG4876	unkown
HJH97_09660	COG2271	Major facilitator Superfamily
HJH97_09670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HJH97_09680	COG2022	thiamine diphosphate biosynthetic process
HJH97_09685	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HJH97_09690	COG0586	Pfam SNARE associated Golgi protein
HJH97_09695	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
HJH97_09705	COG3949	Membrane
HJH97_09710	COG1012	belongs to the aldehyde dehydrogenase family
HJH97_09725	COG2514	catechol 2,3-dioxygenase activity
HJH97_09735	COG1012	belongs to the aldehyde dehydrogenase family
HJH97_09740	COG0778	Nitroreductase
HJH97_09745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HJH97_09755	COG3764	Sortase (surface protein transpeptidase)
HJH97_09780	COG1760	l-serine dehydratase
HJH97_09785	COG1760	l-serine dehydratase
HJH97_09800	COG1070	Carbohydrate kinase
HJH97_09815	COG1869	D-ribose catabolic process
HJH97_09820	COG4975	Glucose uptake
HJH97_09835	COG2843	Capsule synthesis protein
HJH97_09845	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HJH97_09860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HJH97_09870	COG1063	alcohol dehydrogenase
HJH97_09885	COG2190	(PTS) system
HJH97_09885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HJH97_09885	COG1263	PTS System
HJH97_09890	COG0028	Belongs to the TPP enzyme family
HJH97_09895	COG1346	cytolysis
HJH97_09900	COG1380	Effector of murein hydrolase LrgA
HJH97_09905	COG0583	DNA-binding transcription factor activity
HJH97_09925	COG3425	synthase
HJH97_09930	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HJH97_09955	COG1012	belongs to the aldehyde dehydrogenase family
HJH97_09960	COG1028	Short-chain dehydrogenase reductase Sdr
HJH97_09970	COG2217	Heavy metal translocating P-type atpase
HJH97_09975	COG2608	mercury ion transmembrane transporter activity
HJH97_09985	COG0436	Aminotransferase
HJH97_09990	COG3942	CHAP domain
HJH97_10000	COG0741	lytic transglycosylase activity
HJH97_10015	COG1113	amino acid transport
HJH97_10020	COG3001	Fructosamine kinase
HJH97_10025	COG0167	dihydroorotate dehydrogenase activity
HJH97_10040	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HJH97_10055	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HJH97_10060	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HJH97_10065	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HJH97_10075	COG3527	Alpha-acetolactate decarboxylase
HJH97_10080	COG0028	Belongs to the TPP enzyme family
HJH97_10085	COG0039	L-malate dehydrogenase activity
HJH97_10090	COG0583	DNA-binding transcription factor activity
HJH97_10095	COG0531	amino acid
HJH97_10125	COG0446	pyridine nucleotide-disulphide oxidoreductase
HJH97_10130	COG3588	fructose-bisphosphate aldolase
HJH97_10140	COG0579	oxidoreductase
HJH97_10145	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
HJH97_10150	COG0574	Belongs to the PEP-utilizing enzyme family
HJH97_10150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HJH97_10155	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HJH97_10170	COG1473	amidohydrolase
HJH97_10175	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HJH97_10180	COG1012	belongs to the aldehyde dehydrogenase family
HJH97_10185	COG1510	regulation of RNA biosynthetic process
HJH97_10195	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HJH97_10200	COG0602	queuosine metabolic process
HJH97_10205	COG1328	CTP reductase activity
HJH97_10215	COG0529	Catalyzes the synthesis of activated sulfate
HJH97_10220	COG2046	Belongs to the sulfate adenylyltransferase family
HJH97_10225	COG0730	response to heat
HJH97_10240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HJH97_10245	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HJH97_10250	COG0175	sulfate reduction
HJH97_10255	COG0386	Belongs to the glutathione peroxidase family
HJH97_10265	COG1846	Transcriptional regulator
HJH97_10290	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HJH97_10305	COG1136	(ABC) transporter
HJH97_10325	COG1785	Belongs to the alkaline phosphatase family
HJH97_10330	COG0702	epimerase
HJH97_10335	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HJH97_10345	COG4195	phage-related replication protein
HJH97_10370	COG1397	ADP-ribosylglycohydrolase
HJH97_10405	COG0640	Transcriptional regulator
HJH97_10450	COG0583	DNA-binding transcription factor activity
HJH97_10475	COG0659	secondary active sulfate transmembrane transporter activity
HJH97_10510	COG3961	Belongs to the TPP enzyme family
HJH97_10515	COG2843	Capsule synthesis protein
HJH97_10525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HJH97_10535	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HJH97_10545	COG1438	arginine binding
HJH97_10550	COG3227	Zinc metalloprotease (Elastase)
HJH97_10555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HJH97_10590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJH97_10590	COG3711	transcriptional antiterminator
HJH97_10595	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HJH97_10595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HJH97_10595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJH97_10600	COG1482	cell wall glycoprotein biosynthetic process
HJH97_10610	COG1705	Flagellar rod assembly protein muramidase FlgJ
HJH97_10610	COG3942	CHAP domain
HJH97_10620	COG1764	response to oxidative stress
HJH97_10635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HJH97_10640	COG2814	Major facilitator Superfamily
HJH97_10665	COG0438	transferase activity, transferring glycosyl groups
HJH97_10670	COG0653	protein targeting
HJH97_10680	COG1073	alpha beta
HJH97_10690	COG0201	protein transport
HJH97_10710	COG3639	organic phosphonate transmembrane transporter activity
HJH97_10715	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HJH97_10730	COG0737	Belongs to the 5'-nucleotidase family
HJH97_10735	COG2814	Major facilitator Superfamily
HJH97_10750	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HJH97_10755	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HJH97_10760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HJH97_10830	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HJH97_10835	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HJH97_10840	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HJH97_10845	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HJH97_10850	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HJH97_10855	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HJH97_10860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HJH97_10865	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HJH97_10870	COG0037	tRNA processing
HJH97_10875	COG1098	S1 RNA binding domain
HJH97_10885	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HJH97_10890	COG3956	TIGRFAM MazG family protein
HJH97_10895	COG2244	polysaccharide biosynthetic process
HJH97_10900	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HJH97_10905	COG0193	aminoacyl-tRNA hydrolase activity
HJH97_10910	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HJH97_10915	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HJH97_10920	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HJH97_10925	COG2088	sporulation resulting in formation of a cellular spore
HJH97_10930	COG0251	oxidation-reduction process
HJH97_10935	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HJH97_10940	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HJH97_10945	COG4466	Protein conserved in bacteria
HJH97_10950	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HJH97_10955	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HJH97_10960	COG0084	hydrolase, TatD family'
HJH97_10965	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HJH97_10965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HJH97_10970	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HJH97_10975	COG2827	Endonuclease containing a URI domain
HJH97_10980	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HJH97_10985	COG4467	Involved in initiation control of chromosome replication
HJH97_10990	COG1774	PSP1 C-terminal conserved region
HJH97_10995	COG0470	DNA polymerase III
HJH97_11000	COG3870	Protein conserved in bacteria
HJH97_11005	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HJH97_11010	COG1982	Orn Lys Arg decarboxylase major
HJH97_11035	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HJH97_11040	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HJH97_11045	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HJH97_11065	COG2855	membrane
HJH97_11070	COG0583	DNA-binding transcription factor activity
HJH97_11080	COG0493	'glutamate synthase
HJH97_11085	COG0067	glutamate synthase
HJH97_11085	COG0069	glutamate synthase activity
HJH97_11085	COG0070	glutamate synthase
HJH97_11090	COG0583	DNA-binding transcription factor activity
HJH97_11115	COG0438	transferase activity, transferring glycosyl groups
HJH97_11120	COG3942	CHAP domain
HJH97_11120	COG1388	LysM domain
HJH97_11130	COG2011	ABC-type metal ion transport system permease component
HJH97_11135	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HJH97_11140	COG0626	cystathionine gamma-synthase activity
HJH97_11145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HJH97_11155	COG0733	neurotransmitter:sodium symporter activity
HJH97_11165	COG1647	Serine aminopeptidase, S33
HJH97_11180	COG5609	conserved protein (DUF2294)
HJH97_11185	COG3002	Belongs to the UPF0753 family
HJH97_11190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HJH97_11210	COG0523	cobalamin synthesis protein
HJH97_11250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HJH97_11250	COG0519	Catalyzes the synthesis of GMP from XMP
HJH97_11255	COG0516	GMP reductase activity
HJH97_11255	COG0517	IMP dehydrogenase activity
HJH97_11260	COG2233	PERMEase
HJH97_11265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HJH97_11280	COG5183	chlorophyll binding
HJH97_11285	COG1823	symporter activity
HJH97_11290	COG0778	Nitroreductase
HJH97_11300	COG0450	alkyl hydroperoxide reductase
HJH97_11305	COG3634	alkyl hydroperoxide reductase activity
HJH97_11325	COG1280	lysine exporter protein (LysE YggA)
HJH97_11340	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HJH97_11350	COG0360	Binds together with S18 to 16S ribosomal RNA
HJH97_11365	COG0012	GTP binding
HJH97_11370	COG4481	Protein conserved in bacteria
HJH97_11375	COG0668	transmembrane transport
HJH97_11380	COG1475	DNA binding
HJH97_11385	COG0626	cystathionine gamma-synthase activity
HJH97_11390	COG0626	cystathionine gamma-synthase activity
HJH97_11395	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HJH97_11395	COG0646	methionine synthase
HJH97_11400	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HJH97_11410	COG0183	Belongs to the thiolase family
HJH97_11425	COG1476	TRANSCRIPTIONal
HJH97_11435	COG4555	ABC transporter
HJH97_11455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HJH97_11500	COG1136	(ABC) transporter
HJH97_11505	COG0577	efflux transmembrane transporter activity
HJH97_11525	COG0577	efflux transmembrane transporter activity
HJH97_11530	COG1136	(ABC) transporter
HJH97_11565	COG1475	DNA binding
HJH97_11570	COG0357	Ribosomal RNA small subunit methyltransferase G
HJH97_11575	COG0445	tRNA wobble uridine modification
HJH97_11580	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HJH97_11585	COG0594	ribonuclease P activity
HJH97_11605	COG1230	cation diffusion facilitator family transporter
HJH97_11615	COG1937	Protein conserved in bacteria
HJH97_11620	COG2217	Heavy metal translocating P-type atpase
HJH97_11715	COG0659	secondary active sulfate transmembrane transporter activity
HJH97_11725	COG3173	Aminoglycoside phosphotransferase