locus-tag	class	description
JX000_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JX000_00010	COG0592	DNA-directed DNA polymerase activity
JX000_00015	COG2501	S4 domain
JX000_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JX000_00025	COG0187	DNA topoisomerase II activity
JX000_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JX000_00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JX000_00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JX000_00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JX000_00075	COG0359	binds to the 23S rRNA
JX000_00080	COG0305	Participates in initiation and elongation during chromosome replication
JX000_00100	COG0745	RESPONSE REGULATOR receiver
JX000_00105	COG5002	protein histidine kinase activity
JX000_00110	COG4863	YycH protein
JX000_00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JX000_00135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JX000_00140	COG0556	nucleotide-excision repair
JX000_00185	COG3223	Belongs to the PsiE family
JX000_00190	COG1401	restriction endodeoxyribonuclease activity
JX000_00195	COG4268	DNA restriction-modification system
JX000_00240	COG2851	Citrate transporter
JX000_00245	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JX000_00250	COG2814	Major facilitator Superfamily
JX000_00255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JX000_00290	COG2808	Putative FMN-binding domain
JX000_00295	COG0110	maltose O-acetyltransferase activity
JX000_00300	COG1114	Component of the transport system for branched-chain amino acids
JX000_00305	COG2814	Major facilitator Superfamily
JX000_00330	COG1438	arginine binding
JX000_00335	COG0659	secondary active sulfate transmembrane transporter activity
JX000_00355	COG2814	Major facilitator Superfamily
JX000_00370	COG0438	transferase activity, transferring glycosyl groups
JX000_00375	COG0653	protein targeting
JX000_00385	COG1073	alpha beta
JX000_00395	COG0201	protein transport
JX000_00420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JX000_00425	COG0444	Belongs to the ABC transporter superfamily
JX000_00430	COG1124	(ABC) transporter
JX000_00445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JX000_00450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JX000_00460	COG2259	Doxx family
JX000_00470	COG2910	NAD(P)H-binding
JX000_00475	COG1876	peptidase activity
JX000_00480	COG1882	Formate acetyltransferase
JX000_00485	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JX000_00495	COG1288	antiporter activity
JX000_00510	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JX000_00620	COG1785	Belongs to the alkaline phosphatase family
JX000_00660	COG0745	RESPONSE REGULATOR receiver
JX000_00665	COG1131	(ABC) transporter
JX000_00675	COG2205	protein histidine kinase activity
JX000_00690	COG1136	(ABC) transporter
JX000_00705	COG4221	oxidoreductase activity
JX000_00710	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
JX000_00715	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
JX000_00720	COG2962	Rard protein
JX000_00725	COG0471	metal ion transport
JX000_00740	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JX000_00745	COG1054	Belongs to the UPF0176 family
JX000_00770	COG1288	antiporter activity
JX000_00795	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JX000_00815	COG2814	Major facilitator Superfamily
JX000_00820	COG0737	Belongs to the 5'-nucleotidase family
JX000_00840	COG3639	organic phosphonate transmembrane transporter activity
JX000_00880	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JX000_00880	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JX000_00895	COG0477	Major facilitator Superfamily
JX000_00920	COG2409	Drug exporters of the RND superfamily
JX000_00930	COG1764	response to oxidative stress
JX000_00940	COG1705	Flagellar rod assembly protein muramidase FlgJ
JX000_00940	COG3942	CHAP domain
JX000_00960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JX000_00975	COG3227	Zinc metalloprotease (Elastase)
JX000_00980	COG2843	Capsule synthesis protein
JX000_00995	COG3961	Belongs to the TPP enzyme family
JX000_01005	COG4195	phage-related replication protein
JX000_01015	COG1785	Belongs to the alkaline phosphatase family
JX000_01025	COG0745	RESPONSE REGULATOR receiver
JX000_01030	COG2205	protein histidine kinase activity
JX000_01035	COG1136	(ABC) transporter
JX000_01065	COG0175	sulfate reduction
JX000_01070	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JX000_01075	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JX000_01090	COG0730	response to heat
JX000_01095	COG2046	Belongs to the sulfate adenylyltransferase family
JX000_01100	COG0529	Catalyzes the synthesis of activated sulfate
JX000_01110	COG3942	CHAP domain
JX000_01115	COG1328	CTP reductase activity
JX000_01125	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JX000_01135	COG1510	regulation of RNA biosynthetic process
JX000_01140	COG1012	belongs to the aldehyde dehydrogenase family
JX000_01145	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
JX000_01170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JX000_01175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JX000_01175	COG0574	Belongs to the PEP-utilizing enzyme family
JX000_01180	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JX000_01185	COG0579	oxidoreductase
JX000_01190	COG2188	Transcriptional regulator
JX000_01200	COG2723	6-phospho-beta-galactosidase activity
JX000_01220	COG3588	fructose-bisphosphate aldolase
JX000_01225	COG0563	adenylate kinase activity
JX000_01235	COG0446	pyridine nucleotide-disulphide oxidoreductase
JX000_01260	COG0531	amino acid
JX000_01270	COG0583	DNA-binding transcription factor activity
JX000_01275	COG0039	L-malate dehydrogenase activity
JX000_01280	COG0028	Belongs to the TPP enzyme family
JX000_01285	COG3527	Alpha-acetolactate decarboxylase
JX000_01295	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JX000_01300	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JX000_01345	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JX000_01355	COG0167	dihydroorotate dehydrogenase activity
JX000_01360	COG3001	Fructosamine kinase
JX000_01365	COG0596	Alpha beta hydrolase
JX000_01375	COG4221	oxidoreductase activity
JX000_01410	COG1113	amino acid transport
JX000_01425	COG0741	lytic transglycosylase activity
JX000_01440	COG0436	Aminotransferase
JX000_01450	COG2608	mercury ion transmembrane transporter activity
JX000_01465	COG1028	Short-chain dehydrogenase reductase Sdr
JX000_01475	COG1012	belongs to the aldehyde dehydrogenase family
JX000_01505	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JX000_01510	COG3425	synthase
JX000_01520	COG3942	CHAP domain
JX000_01520	COG1388	LysM domain
JX000_01530	COG0583	DNA-binding transcription factor activity
JX000_01535	COG1380	Effector of murein hydrolase LrgA
JX000_01540	COG1346	cytolysis
JX000_01545	COG0028	Belongs to the TPP enzyme family
JX000_01570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JX000_01575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JX000_01590	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JX000_01600	COG2843	Capsule synthesis protein
JX000_01620	COG1070	Carbohydrate kinase
JX000_01630	COG1760	l-serine dehydratase
JX000_01635	COG1760	l-serine dehydratase
JX000_01650	COG3764	Sortase (surface protein transpeptidase)
JX000_01655	COG0561	phosphatase activity
JX000_01660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JX000_01665	COG0778	Nitroreductase
JX000_01670	COG1012	belongs to the aldehyde dehydrogenase family
JX000_01690	COG2314	TM2 domain
JX000_01695	COG2514	catechol 2,3-dioxygenase activity
JX000_01710	COG0583	DNA-binding transcription factor activity
JX000_01715	COG1012	belongs to the aldehyde dehydrogenase family
JX000_01720	COG3949	Membrane
JX000_01730	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
JX000_01735	COG0586	Pfam SNARE associated Golgi protein
JX000_01740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JX000_01745	COG2022	thiamine diphosphate biosynthetic process
JX000_01755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JX000_01760	COG0352	thiamine-phosphate diphosphorylase activity
JX000_01765	COG2271	Major facilitator Superfamily
JX000_01780	COG4876	unkown
JX000_01785	COG2357	RelA SpoT domain protein
JX000_01795	COG1802	Transcriptional regulator
JX000_01800	COG1070	Carbohydrate kinase
JX000_01805	COG2610	gluconate transmembrane transporter activity
JX000_01810	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JX000_01820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JX000_01825	COG0438	transferase activity, transferring glycosyl groups
JX000_01835	COG0556	nucleotide-excision repair
JX000_01840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JX000_01845	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JX000_01850	COG0022	dehydrogenase e1 component
JX000_01855	COG0508	dehydrogenase complex catalyzes the overall conversion of
JX000_01875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JX000_01880	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JX000_01890	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JX000_01895	COG1028	Short-chain dehydrogenase reductase Sdr
JX000_01905	COG1363	Peptidase, m42
JX000_01910	COG4808	Protein conserved in bacteria
JX000_01930	COG0069	glutamate synthase activity
JX000_01945	COG4619	ABC transporter
JX000_01950	COG0390	transport system, permease component
JX000_01955	COG2205	protein histidine kinase activity
JX000_01960	COG0745	RESPONSE REGULATOR receiver
JX000_01965	COG2814	Major facilitator Superfamily
JX000_01970	COG2272	Belongs to the type-B carboxylesterase lipase family
JX000_01975	COG0531	amino acid
JX000_01980	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
JX000_02005	COG1174	glycine betaine transport
JX000_02010	COG1346	cytolysis
JX000_02015	COG1380	Effector of murein hydrolase LrgA
JX000_02025	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JX000_02045	COG0706	membrane insertase activity
JX000_02055	COG0531	amino acid
JX000_02065	COG1113	amino acid transport
JX000_02070	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JX000_02085	COG2814	Major facilitator Superfamily
JX000_02095	COG1929	Belongs to the glycerate kinase type-1 family
JX000_02110	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JX000_02115	COG0741	lytic transglycosylase activity
JX000_02120	COG0588	phosphoglycerate mutase activity
JX000_02130	COG2814	Major facilitator Superfamily
JX000_02135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JX000_02140	COG0765	amino acid transport
JX000_02145	COG1126	abc transporter atp-binding protein
JX000_02165	COG0803	Belongs to the bacterial solute-binding protein 9 family
JX000_02180	COG0454	-acetyltransferase
JX000_02185	COG0747	negative chemotaxis
JX000_02195	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JX000_02200	COG2146	nitrite reductase [NAD(P)H] activity
JX000_02210	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JX000_02215	COG1140	nitrate reductase beta subunit
JX000_02225	COG2181	nitrate reductase activity
JX000_02235	COG4585	Histidine kinase
JX000_02245	COG2223	nitrite transmembrane transporter activity
JX000_02260	COG0778	Nitroreductase
JX000_02270	COG1301	dicarboxylic acid transport
JX000_02295	COG1263	PTS System
JX000_02295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JX000_02320	COG1028	Short-chain dehydrogenase reductase Sdr
JX000_02335	COG1028	Short-chain dehydrogenase reductase Sdr
JX000_02370	COG0492	ferredoxin-NADP+ reductase activity
JX000_02375	COG0456	acetyltransferase
JX000_02380	COG0604	alcohol dehydrogenase
JX000_02385	COG2822	iron ion transport
JX000_02400	COG0805	protein transport
JX000_02405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JX000_02415	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JX000_02415	COG0463	Glycosyl transferase, family 2
JX000_02425	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JX000_02425	COG0463	Glycosyl transferase, family 2
JX000_02430	COG1620	l-lactate permease
JX000_02435	COG0438	transferase activity, transferring glycosyl groups
JX000_02440	COG0579	oxidoreductase
JX000_02470	COG1136	(ABC) transporter
JX000_02500	COG1566	PFAM secretion protein HlyD family protein
JX000_02505	COG2814	Major facilitator Superfamily
JX000_02530	COG0598	Magnesium transport protein CorA
JX000_02535	COG1304	FMN binding
JX000_02540	COG0786	glutamate:sodium symporter activity
JX000_02545	COG1695	Transcriptional regulator
JX000_02560	COG2094	Belongs to the DNA glycosylase MPG family
JX000_02570	COG3620	sequence-specific DNA binding
JX000_02580	COG1069	ribulokinase activity
JX000_02585	COG4152	abc transporter atp-binding protein
JX000_02590	COG1668	transmembrane transport
JX000_02595	COG1742	UPF0060 membrane protein
JX000_02600	COG2017	converts alpha-aldose to the beta-anomer
JX000_02605	COG2258	MOSC domain
JX000_02610	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JX000_02615	COG1266	CAAX protease self-immunity
JX000_02620	COG0010	Belongs to the arginase family
JX000_02625	COG0583	DNA-binding transcription factor activity
JX000_02640	COG1473	amidohydrolase
JX000_02645	COG1028	Short-chain dehydrogenase reductase Sdr
JX000_02665	COG1737	Transcriptional regulator
JX000_02670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JX000_02670	COG1263	PTS System
JX000_02685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JX000_02705	COG1113	amino acid transport
JX000_02715	COG1263	PTS System
JX000_02715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JX000_02720	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JX000_02735	COG1266	CAAX protease self-immunity
JX000_02740	COG2378	regulation of single-species biofilm formation
JX000_02750	COG1316	TRANSCRIPTIONal
JX000_02780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JX000_02785	COG2076	Multidrug Resistance protein
JX000_02790	COG2076	Multidrug Resistance protein
JX000_02795	COG3942	CHAP domain
JX000_02810	COG1757	Na H antiporter
JX000_02815	COG3942	CHAP domain
JX000_02825	COG1846	Transcriptional regulator
JX000_02840	COG0829	nickel cation binding
JX000_02850	COG0830	nickel cation binding
JX000_02855	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
JX000_02860	COG0804	urea catabolic process
JX000_02870	COG0831	urea catabolic process
JX000_02875	COG4413	Urea transporter
JX000_02880	COG0765	amino acid transport
JX000_02885	COG0765	amino acid transport
JX000_02890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JX000_02895	COG1126	abc transporter atp-binding protein
JX000_02900	COG1960	acyl-CoA dehydrogenase activity
JX000_02905	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JX000_02915	COG1268	BioY protein
JX000_02925	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JX000_02930	COG0725	ABC transporter, periplasmic molybdate-binding protein
JX000_02935	COG4149	molybdate abc transporter
JX000_02945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JX000_02950	COG0521	Mo-molybdopterin cofactor biosynthetic process
JX000_02955	COG0315	cyclic pyranopterin monophosphate synthase activity
JX000_02965	COG1763	Mo-molybdopterin cofactor biosynthetic process
JX000_02995	COG2814	Major facilitator Superfamily
JX000_03010	COG2348	transferase activity, transferring amino-acyl groups
JX000_03015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JX000_03040	COG4975	Glucose uptake
JX000_03055	COG2252	PERMEase
JX000_03070	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JX000_03075	COG0088	Forms part of the polypeptide exit tunnel
JX000_03080	COG0089	rRNA binding
JX000_03085	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JX000_03090	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JX000_03095	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JX000_03100	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JX000_03105	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JX000_03115	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JX000_03120	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JX000_03125	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JX000_03135	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JX000_03140	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JX000_03145	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JX000_03150	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JX000_03155	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JX000_03160	COG1841	ribosomal large subunit assembly
JX000_03170	COG0201	protein transport
JX000_03175	COG0563	adenylate kinase activity
JX000_03180	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JX000_03190	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JX000_03195	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JX000_03200	COG0202	RNA polymerase activity
JX000_03215	COG1122	ATPase activity
JX000_03230	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JX000_03245	COG0789	Transcriptional regulator
JX000_03260	COG0698	ribose 5-phosphate isomerase
JX000_03300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JX000_03305	COG2130	NADP-dependent
JX000_03310	COG0604	alcohol dehydrogenase
JX000_03315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JX000_03330	COG1302	Protein conserved in bacteria
JX000_03335	COG4264	IucA IucC family
JX000_03340	COG2814	Major facilitator Superfamily
JX000_03345	COG4264	IucA IucC family
JX000_03350	COG3457	Alanine racemase
JX000_03355	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JX000_03360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JX000_03365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JX000_03370	COG3314	Sporulation integral membrane protein YlbJ
JX000_03375	COG2329	Antibiotic biosynthesis monooxygenase
JX000_03385	COG1988	membrane-bound metal-dependent
JX000_03390	COG4284	Utp--glucose-1-phosphate uridylyltransferase
JX000_03395	COG1272	protein, Hemolysin III
JX000_03410	COG2814	Major facilitator Superfamily
JX000_03415	COG0489	protein tyrosine kinase activity
JX000_03470	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JX000_03495	COG3711	transcriptional antiterminator
JX000_03510	COG0561	phosphatase activity
JX000_03530	COG0640	Transcriptional regulator
JX000_03535	COG0702	epimerase
JX000_03540	COG1482	cell wall glycoprotein biosynthetic process
JX000_03560	COG0783	Belongs to the Dps family
JX000_03565	COG0813	purine-nucleoside phosphorylase activity
JX000_03570	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JX000_03575	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JX000_03580	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JX000_03590	COG1854	S-ribosylhomocysteine lyase activity
JX000_03610	COG5146	pantothenate kinase activity
JX000_03625	COG0504	CTP synthase activity
JX000_03635	COG0191	fructose-bisphosphate aldolase activity
JX000_03640	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JX000_03650	COG1012	belongs to the aldehyde dehydrogenase family
JX000_03655	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JX000_03660	COG0254	rRNA binding
JX000_03665	COG1435	thymidine kinase activity
JX000_03675	COG2890	protein-(glutamine-N5) methyltransferase activity
JX000_03680	COG0009	L-threonylcarbamoyladenylate synthase
JX000_03685	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JX000_03690	COG4475	Protein of unknown function (DUF436)
JX000_03700	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JX000_03705	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JX000_03730	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JX000_03740	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JX000_03745	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JX000_03750	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JX000_03765	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JX000_03775	COG0629	single-stranded DNA binding
JX000_03785	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JX000_03795	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JX000_03805	COG0706	membrane insertase activity
JX000_03810	COG1418	mRNA catabolic process
JX000_03815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JX000_03820	COG1937	Protein conserved in bacteria
JX000_03835	COG0772	Belongs to the SEDS family
JX000_03840	COG1181	Belongs to the D-alanine--D-alanine ligase family
JX000_03845	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JX000_03850	COG0513	Belongs to the DEAD box helicase family
JX000_03860	COG3428	Bacterial PH domain
JX000_03865	COG3402	PFAM membrane-flanked domain
JX000_03870	COG0736	holo-[acyl-carrier-protein] synthase activity
JX000_03875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JX000_03885	COG2337	Toxic component of a toxin-antitoxin (TA) module
JX000_03890	COG2208	phosphoserine phosphatase activity
JX000_03905	COG1191	sigma factor activity
JX000_03910	COG2183	response to ionizing radiation
JX000_03955	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JX000_03960	COG0473	3-isopropylmalate dehydrogenase activity
JX000_03980	COG0028	Belongs to the TPP enzyme family
JX000_03985	COG0129	dihydroxy-acid dehydratase activity
JX000_03990	COG0802	atpase or kinase
JX000_03995	COG1214	PFAM Peptidase M22, glycoprotease
JX000_04000	COG0456	acetyltransferase
JX000_04005	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JX000_04010	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JX000_04015	COG0488	(ABC) transporter
JX000_04030	COG2391	methyltransferase activity
JX000_04035	COG0425	Belongs to the sulfur carrier protein TusA family
JX000_04040	COG1609	Transcriptional regulator
JX000_04045	COG1621	beta-fructofuranosidase activity
JX000_04050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JX000_04060	COG3290	protein histidine kinase activity
JX000_04105	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JX000_04110	COG0459	protein refolding
JX000_04135	COG1725	Transcriptional regulator
JX000_04150	COG1131	(ABC) transporter
JX000_04220	COG0640	Transcriptional regulator
JX000_04240	COG2706	6-phosphogluconolactonase activity
JX000_04245	COG1012	belongs to the aldehyde dehydrogenase family
JX000_04250	COG1227	inorganic diphosphatase activity
JX000_04255	COG1335	isochorismatase
JX000_04265	COG0077	Prephenate dehydratase
JX000_04275	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JX000_04280	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JX000_04285	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
JX000_04295	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JX000_04300	COG4496	protein, YerC YecD
JX000_04305	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JX000_04310	COG0210	DNA helicase
JX000_04315	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JX000_04325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JX000_04335	COG0154	amidase activity
JX000_04340	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JX000_04345	COG1597	lipid kinase activity
JX000_04350	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JX000_04370	COG1528	Iron-storage protein
JX000_04385	COG4129	membrane
JX000_04390	COG0024	Methionine aminopeptidase
JX000_04410	COG2197	response regulator
JX000_04415	COG1295	ribonuclease BN
JX000_04430	COG4840	Belongs to the UPF0435 family
JX000_04435	COG2309	aminopeptidase activity
JX000_04445	COG0535	radical SAM domain protein
JX000_04455	COG0693	protein deglycase activity
JX000_04460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JX000_04475	COG1388	LysM domain
JX000_04475	COG1134	teichoic acid transport
JX000_04485	COG1988	membrane-bound metal-dependent
JX000_04490	COG1194	a g-specific adenine glycosylase
JX000_04495	COG3557	Belongs to the UPF0374 family
JX000_04505	COG4129	membrane
JX000_04510	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JX000_04515	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JX000_04520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JX000_04525	COG0735	belongs to the Fur family
JX000_04695	COG0765	amino acid transport
JX000_04700	COG1126	abc transporter atp-binding protein
JX000_04705	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JX000_04715	COG0363	glucosamine-6-phosphate deaminase activity
JX000_04735	COG0564	pseudouridine synthase activity
JX000_04740	COG2203	Gaf domain
JX000_04740	COG4585	Histidine kinase
JX000_04745	COG2197	response regulator
JX000_04755	COG4399	Belongs to the UPF0754 family
JX000_04760	COG3679	Belongs to the UPF0342 family
JX000_04765	COG0420	3'-5' exonuclease activity
JX000_04775	COG3481	metal-dependent phosphohydrolase, HD sub domain
JX000_04785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JX000_04800	COG0537	adenosine 5'-monophosphoramidase activity
JX000_04805	COG1131	(ABC) transporter
JX000_04810	COG4473	ABC transporter
JX000_04815	COG2329	Antibiotic biosynthesis monooxygenase
JX000_04825	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JX000_04830	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JX000_04835	COG3545	Serine hydrolase
JX000_04885	COG0318	PFAM AMP-dependent synthetase and ligase
JX000_04900	COG0494	nUDIX hydrolase
JX000_04905	COG1506	peptidase
JX000_04915	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JX000_04925	COG0656	L-ascorbic acid biosynthetic process
JX000_04930	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JX000_04935	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JX000_04945	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JX000_04970	COG4193	domain, Protein
JX000_04970	COG3266	domain, Protein
JX000_04970	COG5632	N-Acetylmuramoyl-L-alanine amidase
JX000_04980	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JX000_04980	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JX000_04985	COG0307	riboflavin synthase, alpha
JX000_04990	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JX000_04990	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JX000_04995	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JX000_05000	COG0506	proline dehydrogenase activity
JX000_05005	COG2267	carboxylic ester hydrolase activity
JX000_05015	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JX000_05020	COG1242	4 iron, 4 sulfur cluster binding
JX000_05025	COG2814	Major facilitator Superfamily
JX000_05030	COG0495	leucyl-tRNA aminoacylation
JX000_05035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JX000_05050	COG2081	HI0933 family
JX000_05055	COG2244	polysaccharide biosynthetic process
JX000_05060	COG1187	pseudouridine synthase activity
JX000_05070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JX000_05075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JX000_05080	COG0510	thiamine kinase activity
JX000_05085	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JX000_05090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JX000_05100	COG1363	Peptidase, m42
JX000_05105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JX000_05110	COG4848	Belongs to the UPF0354 family
JX000_05115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JX000_05120	COG1674	ftsk spoiiie
JX000_05125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JX000_05140	COG1605	Chorismate mutase
JX000_05140	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JX000_05145	COG1609	Transcriptional regulator
JX000_05155	COG0454	-acetyltransferase
JX000_05160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JX000_05195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JX000_05200	COG0204	Acyl-transferase
JX000_05220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JX000_05220	COG1263	PTS System
JX000_05230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JX000_05235	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JX000_05240	COG1764	response to oxidative stress
JX000_05245	COG0584	glycerophosphoryl diester phosphodiesterase
JX000_05250	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JX000_05255	COG1956	GAF domain-containing protein
JX000_05260	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JX000_05265	COG1104	cysteine desulfurase activity
JX000_05270	COG0301	tRNA thio-modification
JX000_05280	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JX000_05285	COG0827	DNA restriction-modification system
JX000_05290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JX000_05295	COG0589	response to stress
JX000_05300	COG0686	Belongs to the AlaDH PNT family
JX000_05305	COG0006	proline dipeptidase activity
JX000_05310	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JX000_05320	COG4109	DRTGG domain
JX000_05325	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JX000_05330	COG0587	DNA-directed DNA polymerase activity
JX000_05335	COG0281	malic enzyme
JX000_05340	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JX000_05350	COG0205	6-phosphofructokinase activity
JX000_05355	COG0469	pyruvate kinase activity
JX000_05360	COG1113	amino acid transport
JX000_05365	COG0372	Belongs to the citrate synthase family
JX000_05370	COG0538	isocitrate dehydrogenase activity
JX000_05375	COG0745	RESPONSE REGULATOR receiver
JX000_05380	COG5002	protein histidine kinase activity
JX000_05385	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JX000_05385	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JX000_05390	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JX000_05400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JX000_05405	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JX000_05410	COG3611	Membrane attachment protein
JX000_05415	COG1484	DNA-dependent DNA replication
JX000_05425	COG0833	amino acid
JX000_05430	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JX000_05435	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JX000_05440	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JX000_05445	COG4112	unkown
JX000_05455	COG0544	peptidyl-prolyl cis-trans isomerase activity
JX000_05460	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JX000_05465	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JX000_05470	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JX000_05475	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JX000_05480	COG0181	hydroxymethylbilane synthase activity
JX000_05490	COG0113	porphobilinogen synthase activity
JX000_05495	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JX000_05505	COG2818	Glycosylase
JX000_05510	COG0525	valine-tRNA ligase activity
JX000_05515	COG0285	dihydrofolate synthase activity
JX000_05525	COG2003	Belongs to the UPF0758 family
JX000_05560	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JX000_05565	COG2868	ribosomal protein
JX000_05570	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JX000_05575	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JX000_05580	COG4492	Belongs to the UPF0735 family
JX000_05585	COG0632	four-way junction helicase activity
JX000_05595	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JX000_05605	COG1862	Preprotein translocase
JX000_05610	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JX000_05610	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JX000_05615	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JX000_05615	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JX000_05625	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JX000_05635	COG0860	N-Acetylmuramoyl-L-alanine amidase
JX000_05645	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JX000_05655	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JX000_05660	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JX000_05665	COG1959	2 iron, 2 sulfur cluster binding
JX000_05675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JX000_05680	COG1104	cysteine desulfurase activity
JX000_05685	COG0482	sulfurtransferase activity
JX000_05695	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JX000_05705	COG4472	Bacterial protein of unknown function (DUF965)
JX000_05710	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JX000_05715	COG3906	Belongs to the UPF0473 family
JX000_05720	COG4122	O-methyltransferase activity
JX000_05725	COG0826	peptidase U32
JX000_05730	COG0826	peptidase U32
JX000_05735	COG0572	uridine kinase
JX000_05740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JX000_05745	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JX000_05750	COG1984	allophanate hydrolase subunit 2
JX000_05755	COG0511	ligase activity, forming carbon-carbon bonds
JX000_05760	COG0439	Biotin carboxylase
JX000_05770	COG1914	H( )-stimulated, divalent metal cation uptake system
JX000_05775	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JX000_05780	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JX000_05785	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JX000_05790	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JX000_05795	COG1534	Rna-binding protein
JX000_05800	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JX000_05805	COG1713	HD superfamily hydrolase involved in NAD metabolism
JX000_05810	COG0799	negative regulation of ribosome biogenesis
JX000_05815	COG2226	methyltransferase
JX000_05825	COG2131	deaminase
JX000_05835	COG1466	dna polymerase III delta subunit
JX000_05840	COG0268	Binds directly to 16S ribosomal RNA
JX000_05845	COG0481	GTPase activity
JX000_05850	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JX000_05860	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JX000_05865	COG0443	Heat shock 70 kDa protein
JX000_05870	COG0484	heat shock protein binding
JX000_05875	COG2264	protein methyltransferase activity
JX000_05880	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JX000_05885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JX000_05895	COG1030	water channel activity
JX000_05900	COG4864	UPF0365 protein
JX000_05910	COG1702	phosphate starvation-inducible protein PhoH
JX000_05920	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JX000_05930	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JX000_05935	COG1381	Involved in DNA repair and RecF pathway recombination
JX000_05940	COG0423	glycine-tRNA ligase activity
JX000_05945	COG0517	IMP dehydrogenase activity
JX000_05950	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JX000_05960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JX000_05965	COG2384	SAM-dependent methyltransferase
JX000_05970	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JX000_05975	COG0513	Belongs to the DEAD box helicase family
JX000_05980	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JX000_05985	COG1121	(ABC) transporter
JX000_05990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JX000_06005	COG0768	penicillin binding
JX000_06010	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JX000_06015	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JX000_06025	COG4483	Protein conserved in bacteria
JX000_06030	COG1940	carbohydrate kinase activity
JX000_06035	COG0011	TIGRFAM Protein of
JX000_06040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JX000_06045	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JX000_06055	COG4537	Required for transformation and DNA binding
JX000_06070	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JX000_06075	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JX000_06080	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JX000_06090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JX000_06095	COG0095	Lipoate-protein ligase
JX000_06110	COG0006	proline dipeptidase activity
JX000_06115	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JX000_06120	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JX000_06130	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JX000_06140	COG0511	ligase activity, forming carbon-carbon bonds
JX000_06145	COG0439	Biotin carboxylase
JX000_06150	COG1302	Protein conserved in bacteria
JX000_06155	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JX000_06165	COG1722	exodeoxyribonuclease VII activity
JX000_06170	COG0142	geranyltranstransferase activity
JX000_06175	COG1438	arginine binding
JX000_06180	COG0497	DNA recombination
JX000_06185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JX000_06190	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JX000_06195	COG0022	dehydrogenase e1 component
JX000_06200	COG0508	dehydrogenase complex catalyzes the overall conversion of
JX000_06210	COG4129	membrane
JX000_06215	COG2195	Cleaves the N-terminal amino acid of tripeptides
JX000_06220	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JX000_06225	COG0366	Alpha amylase catalytic
JX000_06235	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JX000_06245	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JX000_06250	COG1028	Short-chain dehydrogenase reductase Sdr
JX000_06255	COG0667	Aldo Keto reductase
JX000_06260	COG0494	nUDIX hydrolase
JX000_06265	COG0735	belongs to the Fur family
JX000_06270	COG4974	Belongs to the 'phage' integrase family
JX000_06280	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JX000_06285	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JX000_06290	COG1187	pseudouridine synthase activity
JX000_06295	COG0745	RESPONSE REGULATOR receiver
JX000_06310	COG1141	Ferredoxin
JX000_06320	COG0514	ATP-dependent DNA helicase (RecQ)
JX000_06330	COG0492	ferredoxin-NADP+ reductase activity
JX000_06345	COG0539	negative regulation of cytoplasmic translation
JX000_06350	COG1160	GTP binding
JX000_06355	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JX000_06370	COG2226	methyltransferase
JX000_06385	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JX000_06390	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JX000_06395	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JX000_06405	COG5582	Belongs to the UPF0302 family
JX000_06410	COG4347	Protein of unknown function (DUF1405)
JX000_06415	COG2738	Putative neutral zinc metallopeptidase
JX000_06420	COG1694	Mazg nucleotide pyrophosphohydrolase
JX000_06425	COG0438	transferase activity, transferring glycosyl groups
JX000_06430	COG0617	tRNA 3'-terminal CCA addition
JX000_06440	COG1199	ATP-dependent helicase activity
JX000_06440	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JX000_06445	COG0017	Asparaginyl-tRNA synthetase
JX000_06450	COG3935	DnaD domain protein
JX000_06455	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JX000_06465	COG4499	WXG100 protein secretion system (Wss), protein YukC
JX000_06465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JX000_06470	COG3331	DNA recombination
JX000_06485	COG3599	regulation of cell shape
JX000_06495	COG0116	Belongs to the methyltransferase superfamily
JX000_06505	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JX000_06510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JX000_06575	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JX000_06585	COG1413	lyase activity
JX000_06590	COG1413	lyase activity
JX000_06620	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JX000_06625	COG2190	(PTS) system
JX000_06635	COG0793	Belongs to the peptidase S41A family
JX000_06645	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JX000_06650	COG0671	phosphoesterase, PA-phosphatase related
JX000_06655	COG0745	RESPONSE REGULATOR receiver
JX000_06660	COG5002	protein histidine kinase activity
JX000_06665	COG0567	Dehydrogenase, E1 component
JX000_06675	COG1131	(ABC) transporter
JX000_06700	COG0714	Associated with various cellular activities
JX000_06705	COG4548	von Willebrand factor, type A
JX000_06710	COG1114	Component of the transport system for branched-chain amino acids
JX000_06715	COG3853	Toxic anion resistance protein (TelA)
JX000_06725	COG1254	Belongs to the acylphosphatase family
JX000_06735	COG1278	Cold shock
JX000_06750	COG1473	amidohydrolase
JX000_06760	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JX000_06765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JX000_06770	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JX000_06775	COG0527	aspartate kinase activity
JX000_06780	COG0488	(ABC) transporter
JX000_06785	COG2996	Protein conserved in bacteria
JX000_06790	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JX000_06795	COG0573	inorganic phosphate transmembrane transporter activity
JX000_06800	COG0581	inorganic phosphate transmembrane transporter activity
JX000_06805	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JX000_06850	COG0561	phosphatase activity
JX000_06855	COG2348	transferase activity, transferring amino-acyl groups
JX000_06860	COG2348	transferase activity, transferring amino-acyl groups
JX000_06880	COG0134	indole-3-glycerol-phosphate synthase activity
JX000_06890	COG0512	Glutamine amidotransferase of anthranilate synthase
JX000_06900	COG1363	Peptidase, m42
JX000_06905	COG0287	Prephenate dehydrogenase
JX000_06910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JX000_06915	COG1942	4-Oxalocrotonate Tautomerase
JX000_06930	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JX000_06930	COG0392	lysyltransferase activity
JX000_06935	COG0628	permease
JX000_06940	COG3711	transcriptional antiterminator
JX000_06945	COG1115	amino acid carrier protein
JX000_06950	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JX000_06955	COG0187	DNA topoisomerase II activity
JX000_06965	COG4841	protein insertion into membrane
JX000_06970	COG0824	Thioesterase
JX000_06975	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JX000_06980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JX000_06985	COG1970	mechanosensitive ion channel activity
JX000_07000	COG4846	Membrane protein involved in cytochrome C biogenesis
JX000_07010	COG3763	UPF0154 protein
JX000_07020	COG4224	UPF0291 protein
JX000_07045	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JX000_07060	COG0833	amino acid
JX000_07075	COG0083	homoserine kinase activity
JX000_07080	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JX000_07085	COG0460	homoserine dehydrogenase
JX000_07090	COG0527	aspartate kinase activity
JX000_07105	COG1525	nuclease
JX000_07120	COG2197	response regulator
JX000_07125	COG4585	Histidine kinase
JX000_07180	COG0789	Transcriptional regulator
JX000_07185	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JX000_07190	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JX000_07195	COG0386	Belongs to the glutathione peroxidase family
JX000_07200	COG1923	regulation of RNA biosynthetic process
JX000_07205	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JX000_07215	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JX000_07225	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JX000_07230	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JX000_07235	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JX000_07240	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JX000_07250	COG4550	Control of competence regulator ComK, YlbF/YmcA
JX000_07255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JX000_07265	COG4195	phage-related replication protein
JX000_07270	COG1013	pyruvate-flavodoxin oxidoreductase activity
JX000_07275	COG0674	pyruvate-flavodoxin oxidoreductase activity
JX000_07275	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JX000_07280	COG1692	metallophosphoesterase
JX000_07290	COG1418	mRNA catabolic process
JX000_07295	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JX000_07300	COG1058	Belongs to the CinA family
JX000_07300	COG1546	Belongs to the CinA family
JX000_07310	COG1426	Protein conserved in bacteria
JX000_07320	COG0300	oxidoreductase activity
JX000_07325	COG0612	Peptidase, M16
JX000_07330	COG0612	Peptidase, M16
JX000_07335	COG2188	Transcriptional regulator
JX000_07350	COG1185	polyribonucleotide nucleotidyltransferase activity
JX000_07355	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JX000_07360	COG0196	riboflavin kinase activity
JX000_07365	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JX000_07370	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JX000_07375	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JX000_07380	COG1358	cellular component organization or biogenesis
JX000_07385	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JX000_07390	COG0195	Participates in both transcription termination and antitermination
JX000_07395	COG0779	Required for maturation of 30S ribosomal subunits
JX000_07400	COG2176	DNA-directed DNA polymerase activity
JX000_07405	COG0442	prolyl-tRNA aminoacylation
JX000_07415	COG4589	Belongs to the CDS family
JX000_07420	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JX000_07425	COG0233	cytoplasmic translational termination
JX000_07430	COG0528	UMP kinase activity
JX000_07435	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JX000_07440	COG0052	Belongs to the universal ribosomal protein uS2 family
JX000_07455	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JX000_07460	COG4974	Belongs to the 'phage' integrase family
JX000_07465	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JX000_07470	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JX000_07475	COG0758	DNA mediated transformation
JX000_07480	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JX000_07485	COG0045	succinate-CoA ligase (ADP-forming) activity
JX000_07490	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JX000_07500	COG4485	Bacterial membrane protein, YfhO
JX000_07515	COG0336	Belongs to the RNA methyltransferase TrmD family
JX000_07520	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JX000_07525	COG0228	four-way junction DNA binding
JX000_07530	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JX000_07535	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JX000_07540	COG0552	protein localization to endoplasmic reticulum
JX000_07545	COG1196	nuclear chromosome segregation
JX000_07550	COG0571	ribonuclease III activity
JX000_07555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JX000_07570	COG0416	fatty acid biosynthetic process
JX000_07575	COG1349	DNA-binding transcription factor activity
JX000_07580	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JX000_07585	COG1461	Dihydroxyacetone kinase
JX000_07590	COG1302	Protein conserved in bacteria
JX000_07595	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JX000_07605	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JX000_07610	COG1162	GTPase activity
JX000_07620	COG0631	protein serine/threonine phosphatase activity
JX000_07625	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JX000_07630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JX000_07630	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JX000_07635	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JX000_07640	COG0242	peptide deformylase activity
JX000_07650	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JX000_07655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JX000_07660	COG1758	RNA polymerase activity
JX000_07665	COG0194	GDP metabolic process
JX000_07685	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JX000_07690	COG0284	orotidine-5'-phosphate decarboxylase activity
JX000_07695	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JX000_07700	COG0505	Belongs to the CarA family
JX000_07705	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JX000_07710	COG0540	Belongs to the ATCase OTCase family
JX000_07715	COG2233	PERMEase
JX000_07720	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JX000_07730	COG0564	pseudouridine synthase activity
JX000_07740	COG1388	LysM domain
JX000_07740	COG3942	CHAP domain
JX000_07750	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JX000_07755	COG3599	regulation of cell shape
JX000_07765	COG0762	integral membrane protein
JX000_07770	COG1799	cell septum assembly
JX000_07775	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JX000_07780	COG1496	oxidoreductase activity
JX000_07785	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JX000_07790	COG0849	cell division
JX000_07795	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JX000_07805	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JX000_07810	COG0768	penicillin binding
JX000_07815	COG4839	cell division protein FtsL
JX000_07820	COG0275	rRNA processing
JX000_07830	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JX000_07840	COG1011	Hydrolase
JX000_07890	COG5632	N-Acetylmuramoyl-L-alanine amidase
JX000_07890	COG1388	LysM domain
JX000_07990	COG0740	serine-type endopeptidase activity
JX000_08095	COG0556	nucleotide-excision repair
JX000_08170	COG0582	viral genome integration into host DNA
JX000_08180	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JX000_08185	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JX000_08190	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JX000_08195	COG1053	succinate dehydrogenase
JX000_08200	COG2009	succinate dehydrogenase
JX000_08205	COG0322	excinuclease ABC activity
JX000_08210	COG3118	belongs to the thioredoxin family
JX000_08215	COG1193	negative regulation of DNA recombination
JX000_08220	COG1796	DNA polymerase
JX000_08220	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JX000_08230	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JX000_08235	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JX000_08240	COG0072	phenylalanine-tRNA ligase activity
JX000_08240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JX000_08245	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JX000_08250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JX000_08255	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JX000_08270	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JX000_08275	COG0742	ribosomal rna small subunit methyltransferase
JX000_08290	COG0584	glycerophosphoryl diester phosphodiesterase
JX000_08295	COG3679	Belongs to the UPF0342 family
JX000_08310	COG0109	protoheme IX farnesyltransferase activity
JX000_08315	COG1612	heme a metabolic process
JX000_08325	COG0772	Belongs to the SEDS family
JX000_08330	COG4838	Belongs to the UPF0358 family
JX000_08335	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JX000_08340	COG4896	Protein conserved in bacteria
JX000_08345	COG1217	gtp-binding protein TYPA
JX000_08355	COG0483	inositol monophosphate 1-phosphatase activity
JX000_08360	COG4493	Belongs to the UPF0637 family
JX000_08390	COG1176	ABC-type spermidine putrescine transport system, permease component I
JX000_08405	COG4476	Belongs to the UPF0223 family
JX000_08415	COG0508	dehydrogenase complex catalyzes the overall conversion of
JX000_08435	COG0242	peptide deformylase activity
JX000_08440	COG5503	Protein of unknown function (DUF1447)
JX000_08445	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JX000_08450	COG0569	domain protein
JX000_08455	COG1294	oxidase, subunit
JX000_08460	COG1271	oxidase subunit
JX000_08470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JX000_08475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JX000_08485	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JX000_08505	COG4172	Belongs to the ABC transporter superfamily
JX000_08510	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JX000_08515	COG0151	Belongs to the GarS family
JX000_08520	COG0138	bifunctional purine biosynthesis protein purh
JX000_08530	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JX000_08545	COG0047	phosphoribosylformylglycinamidine synthase activity
JX000_08550	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JX000_08555	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JX000_08565	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JX000_08570	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JX000_08575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JX000_08575	COG1017	nitric oxide dioxygenase activity
JX000_08585	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JX000_08600	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JX000_08615	COG1316	TRANSCRIPTIONal
JX000_08640	COG3594	Acyltransferase
JX000_08645	COG0436	Aminotransferase
JX000_08650	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JX000_08660	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JX000_08665	COG1169	isochorismate synthase
JX000_08670	COG1575	Belongs to the MenA family. Type 1 subfamily
JX000_08680	COG2314	TM2 domain
JX000_08715	COG4873	Protein conserved in bacteria
JX000_08730	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JX000_08735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JX000_08740	COG0861	Integral membrane protein TerC family
JX000_08745	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JX000_08755	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JX000_08760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JX000_08765	COG2814	Major facilitator Superfamily
JX000_08770	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JX000_08775	COG2382	esterase
JX000_08780	COG1115	amino acid carrier protein
JX000_08785	COG0628	permease
JX000_08795	COG0475	glutathione-regulated potassium exporter activity
JX000_08795	COG0569	domain protein
JX000_08800	COG2239	Acts as a magnesium transporter
JX000_08805	COG0564	pseudouridine synthase activity
JX000_08810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JX000_08815	COG2357	RelA SpoT domain protein
JX000_08830	COG2346	COG2346, Truncated hemoglobins
JX000_08835	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JX000_08840	COG1164	Oligoendopeptidase f
JX000_08850	COG4862	establishment of competence for transformation
JX000_08855	COG1393	Belongs to the ArsC family
JX000_08860	COG0180	Tryptophanyl-tRNA synthetase
JX000_08865	COG4166	transmembrane transport
JX000_08870	COG4608	Belongs to the ABC transporter superfamily
JX000_08875	COG0444	Belongs to the ABC transporter superfamily
JX000_08880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JX000_08885	COG0601	transmembrane transport
JX000_08900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JX000_08910	COG0542	response to heat
JX000_08925	COG0561	phosphatase activity
JX000_08930	COG0446	pyridine nucleotide-disulphide oxidoreductase
JX000_08945	COG1074	ATP-dependent DNA helicase activity
JX000_08950	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JX000_08965	COG0398	Pfam SNARE associated Golgi protein
JX000_08975	COG0137	argininosuccinate synthase activity
JX000_08980	COG0165	Argininosuccinate lyase
JX000_08985	COG0584	glycerophosphoryl diester phosphodiesterase
JX000_08990	COG0584	glycerophosphoryl diester phosphodiesterase
JX000_09010	COG1902	pentaerythritol trinitrate reductase activity
JX000_09015	COG1098	S1 RNA binding domain
JX000_09030	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JX000_09030	COG2111	Na H antiporter
JX000_09035	COG2111	Na H antiporter
JX000_09040	COG1006	Multisubunit Na H antiporter MnhC subunit
JX000_09045	COG0651	ATP synthesis coupled electron transport
JX000_09055	COG2212	antiporter activity
JX000_09075	COG2050	protein possibly involved in aromatic compounds catabolism
JX000_09080	COG2056	Na+-H+ antiporter family
JX000_09085	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JX000_09095	COG0316	Belongs to the HesB IscA family
JX000_09100	COG4844	belongs to the
JX000_09105	COG1252	NADH dehydrogenase
JX000_09110	COG4837	Protein of unknown function (DUF1462)
JX000_09115	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JX000_09120	COG0583	DNA-binding transcription factor activity
JX000_09130	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JX000_09140	COG1696	Membrane protein involved in D-alanine export
JX000_09145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JX000_09165	COG2445	Protein of unknown function DUF86
JX000_09175	COG4470	Protein conserved in bacteria
JX000_09180	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JX000_09185	COG0737	Belongs to the 5'-nucleotidase family
JX000_09190	COG0730	response to heat
JX000_09195	COG1801	Protein of unknown function DUF72
JX000_09200	COG2070	2-Nitropropane dioxygenase
JX000_09205	COG1253	flavin adenine dinucleotide binding
JX000_09210	COG0719	Fe-S assembly protein
JX000_09215	COG0822	iron-sulfur transferase activity
JX000_09220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JX000_09225	COG0719	Fe-S assembly protein
JX000_09230	COG0396	ATPase activity
JX000_09240	COG3237	CsbD-like
JX000_09245	COG1464	Belongs to the NlpA lipoprotein family
JX000_09250	COG2011	ABC-type metal ion transport system permease component
JX000_09255	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JX000_09265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JX000_09270	COG0509	glycine decarboxylation via glycine cleavage system
JX000_09275	COG1393	Belongs to the ArsC family
JX000_09280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JX000_09290	COG0710	3-dehydroquinate dehydratase activity
JX000_09295	COG1764	response to oxidative stress
JX000_09305	COG0406	alpha-ribazole phosphatase activity
JX000_09340	COG4195	phage-related replication protein
JX000_09365	COG1278	Cold shock
JX000_09390	COG0656	L-ascorbic acid biosynthetic process
JX000_09445	COG0557	exoribonuclease II activity
JX000_09450	COG1647	Serine aminopeptidase, S33
JX000_09455	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JX000_09465	COG0148	phosphopyruvate hydratase activity
JX000_09470	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JX000_09475	COG0149	triose-phosphate isomerase activity
JX000_09480	COG0126	phosphoglycerate kinase activity
JX000_09490	COG2390	Transcriptional regulator
JX000_09515	COG0740	serine-type endopeptidase activity
JX000_09555	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JX000_09570	COG1481	regulation of sporulation
JX000_09575	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JX000_09580	COG1660	Displays ATPase and GTPase activities
JX000_09585	COG0492	ferredoxin-NADP+ reductase activity
JX000_09600	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JX000_09610	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JX000_09615	COG0556	nucleotide-excision repair
JX000_09630	COG3942	CHAP domain
JX000_09630	COG1388	LysM domain
JX000_09640	COG0653	protein targeting
JX000_09645	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JX000_09650	COG1040	competence protein
JX000_09655	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JX000_09665	COG1739	Uncharacterized protein family UPF0029
JX000_09670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JX000_09690	COG2195	Cleaves the N-terminal amino acid of tripeptides
JX000_09695	COG1929	Belongs to the glycerate kinase type-1 family
JX000_09715	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JX000_09730	COG4604	ABC transporter, ATP-binding protein
JX000_09735	COG4605	iron ion homeostasis
JX000_09740	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JX000_09745	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JX000_09750	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JX000_09755	COG1780	Probably involved in ribonucleotide reductase function
JX000_09770	COG3104	oligopeptide transport
JX000_09775	COG1597	lipid kinase activity
JX000_09785	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JX000_09790	COG1174	glycine betaine transport
JX000_09795	COG1125	glycine betaine transport
JX000_09795	COG0517	IMP dehydrogenase activity
JX000_09800	COG0514	ATP-dependent DNA helicase (RecQ)
JX000_09805	COG0488	(ABC) transporter
JX000_09815	COG1368	sulfuric ester hydrolase activity
JX000_09835	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JX000_09840	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JX000_09845	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JX000_09845	COG0512	Glutamine amidotransferase of anthranilate synthase
JX000_09850	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JX000_09855	COG0720	synthase
JX000_09860	COG0602	queuosine metabolic process
JX000_09870	COG0463	Glycosyl transferase, family 2
JX000_09875	COG0656	L-ascorbic acid biosynthetic process
JX000_09880	COG1253	flavin adenine dinucleotide binding
JX000_09885	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JX000_09890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JX000_09890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JX000_09890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JX000_09895	COG1105	Belongs to the carbohydrate kinase PfkB family
JX000_09900	COG1349	DNA-binding transcription factor activity
JX000_09905	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JX000_09930	COG0415	Belongs to the DNA photolyase family
JX000_09935	COG0471	metal ion transport
JX000_09940	COG0039	L-malate dehydrogenase activity
JX000_09950	COG4989	oxidoreductase activity
JX000_09955	COG0523	cobalamin synthesis protein
JX000_09965	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JX000_09970	COG4988	ABC transporter
JX000_09975	COG1968	undecaprenyl-diphosphatase activity
JX000_09985	COG1671	Belongs to the UPF0178 family
JX000_09990	COG1611	Belongs to the LOG family
JX000_10005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JX000_10030	COG2839	Protein conserved in bacteria
JX000_10035	COG2814	Major facilitator Superfamily
JX000_10040	COG0583	DNA-binding transcription factor activity
JX000_10055	COG0217	transcriptional regulatory protein
JX000_10065	COG0662	Cupin 2, conserved barrel domain protein
JX000_10065	COG2207	Transcriptional regulator
JX000_10075	COG1388	LysM domain
JX000_10075	COG3942	CHAP domain
JX000_10080	COG0306	phosphate transporter
JX000_10085	COG1392	Phosphate transport regulator
JX000_10095	COG0577	efflux transmembrane transporter activity
JX000_10100	COG1136	(ABC) transporter
JX000_10105	COG2205	protein histidine kinase activity
JX000_10115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JX000_10125	COG0657	acetylesterase activity
JX000_10130	COG3949	Membrane
JX000_10140	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
JX000_10150	COG2376	Dihydroxyacetone kinase
JX000_10155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JX000_10160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JX000_10165	COG1120	ATPase activity
JX000_10170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JX000_10175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JX000_10180	COG1132	(ABC) transporter
JX000_10185	COG1686	Belongs to the peptidase S11 family
JX000_10190	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JX000_10200	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JX000_10205	COG1682	transport, permease protein
JX000_10210	COG1134	teichoic acid transport
JX000_10215	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JX000_10230	COG1121	(ABC) transporter
JX000_10235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JX000_10240	COG0803	Belongs to the bacterial solute-binding protein 9 family
JX000_10250	COG1320	monovalent cation:proton antiporter activity
JX000_10260	COG1863	multisubunit Na H antiporter MnhE subunit
JX000_10265	COG0651	ATP synthesis coupled electron transport
JX000_10270	COG1006	Multisubunit Na H antiporter MnhC subunit
JX000_10275	COG2111	Na H antiporter
JX000_10280	COG2111	Na H antiporter
JX000_10280	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JX000_10315	COG2267	carboxylic ester hydrolase activity
JX000_10335	COG0546	phosphoglycolate phosphatase activity
JX000_10340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JX000_10345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JX000_10350	COG0534	Mate efflux family protein
JX000_10360	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JX000_10365	COG0018	arginyl-trna synthetase
JX000_10390	COG1078	dGTPase activity
JX000_10395	COG0519	Catalyzes the synthesis of GMP from XMP
JX000_10400	COG0655	NAD(P)H dehydrogenase (quinone) activity
JX000_10405	COG0667	Aldo Keto reductase
JX000_10410	COG4844	belongs to the
JX000_10425	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JX000_10430	COG0095	Lipoate-protein ligase
JX000_10435	COG0280	phosphate acetyltransferase
JX000_10440	COG3253	May function as heme-dependent peroxidase
JX000_10460	COG2363	Small membrane protein
JX000_10475	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
JX000_10500	COG0477	Major facilitator Superfamily
JX000_10515	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JX000_10520	COG0363	glucosamine-6-phosphate deaminase activity
JX000_10530	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JX000_10535	COG1469	GTP cyclohydrolase I activity
JX000_10540	COG2271	Major facilitator Superfamily
JX000_10545	COG0438	transferase activity, transferring glycosyl groups
JX000_10560	COG0431	NADPH-dependent FMN reductase
JX000_10565	COG0561	phosphatase activity
JX000_10575	COG1428	Deoxynucleoside kinase
JX000_10580	COG1428	Deoxynucleoside kinase
JX000_10590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JX000_10600	COG0737	Belongs to the 5'-nucleotidase family
JX000_10615	COG1063	alcohol dehydrogenase
JX000_10620	COG2814	Major facilitator Superfamily
JX000_10625	COG1349	DNA-binding transcription factor activity
JX000_10645	COG1473	amidohydrolase
JX000_10650	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JX000_10655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JX000_10660	COG0049	tRNA binding
JX000_10665	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JX000_10675	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JX000_10680	COG0085	RNA polymerase activity
JX000_10685	COG2813	Specifically methylates the guanine in position
JX000_10690	COG0222	ribosome binding
JX000_10695	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JX000_10700	COG0081	regulation of translation
JX000_10705	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JX000_10710	COG0250	Participates in transcription elongation, termination and antitermination
JX000_10720	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JX000_10730	COG3688	RNA-binding protein containing a PIN domain
JX000_10740	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JX000_10745	COG0215	cysteine-tRNA ligase activity
JX000_10755	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JX000_10760	COG4956	integral membrane protein (PIN domain superfamily)
JX000_10765	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JX000_10770	COG0542	response to heat
JX000_10775	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JX000_10780	COG3880	PFAM UvrB UvrC protein
JX000_10790	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JX000_10795	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JX000_10800	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JX000_10805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JX000_10890	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JX000_10895	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JX000_10900	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JX000_10920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JX000_10935	COG1098	S1 RNA binding domain
JX000_10945	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JX000_10950	COG3956	TIGRFAM MazG family protein
JX000_10955	COG2244	polysaccharide biosynthetic process
JX000_10960	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JX000_10965	COG0193	aminoacyl-tRNA hydrolase activity
JX000_10970	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JX000_10975	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JX000_10980	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JX000_10985	COG2088	sporulation resulting in formation of a cellular spore
JX000_10990	COG0251	oxidation-reduction process
JX000_10995	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JX000_11000	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JX000_11005	COG4466	Protein conserved in bacteria
JX000_11010	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JX000_11015	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JX000_11020	COG0084	hydrolase, TatD family'
JX000_11025	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JX000_11025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JX000_11030	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JX000_11035	COG2827	Endonuclease containing a URI domain
JX000_11040	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JX000_11045	COG4467	Involved in initiation control of chromosome replication
JX000_11050	COG1774	PSP1 C-terminal conserved region
JX000_11055	COG0470	DNA polymerase III
JX000_11060	COG3870	Protein conserved in bacteria
JX000_11070	COG1982	Orn Lys Arg decarboxylase major
JX000_11075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JX000_11095	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JX000_11100	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JX000_11105	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JX000_11120	COG2188	Transcriptional regulator
JX000_11125	COG0366	Alpha amylase catalytic
JX000_11130	COG1263	PTS System
JX000_11130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JX000_11140	COG0493	'glutamate synthase
JX000_11145	COG0069	glutamate synthase activity
JX000_11145	COG0070	glutamate synthase
JX000_11145	COG0067	glutamate synthase
JX000_11150	COG0583	DNA-binding transcription factor activity
JX000_11165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JX000_11180	COG0438	transferase activity, transferring glycosyl groups
JX000_11195	COG1278	Cold shock
JX000_11200	COG3759	membrane
JX000_11225	COG1846	Transcriptional regulator
JX000_11230	COG0626	cystathionine gamma-synthase activity
JX000_11235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JX000_11250	COG1279	arginine transmembrane transporter activity
JX000_11255	COG0733	neurotransmitter:sodium symporter activity
JX000_11265	COG1647	Serine aminopeptidase, S33
JX000_11270	COG0671	phosphoesterase, PA-phosphatase related
JX000_11285	COG5609	conserved protein (DUF2294)
JX000_11290	COG3002	Belongs to the UPF0753 family
JX000_11295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JX000_11310	COG0523	cobalamin synthesis protein
JX000_11320	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JX000_11320	COG0519	Catalyzes the synthesis of GMP from XMP
JX000_11325	COG0516	GMP reductase activity
JX000_11325	COG0517	IMP dehydrogenase activity
JX000_11330	COG2233	PERMEase
JX000_11335	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JX000_11350	COG5183	chlorophyll binding
JX000_11355	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JX000_11360	COG1823	symporter activity
JX000_11365	COG0778	Nitroreductase
JX000_11385	COG0450	alkyl hydroperoxide reductase
JX000_11390	COG3634	alkyl hydroperoxide reductase activity
JX000_11415	COG1280	lysine exporter protein (LysE YggA)
JX000_11435	COG3728	DNA packaging
JX000_11435	COG5484	DNA packaging
JX000_11515	COG0582	viral genome integration into host DNA
JX000_11520	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JX000_11530	COG0360	Binds together with S18 to 16S ribosomal RNA
JX000_11545	COG0012	GTP binding
JX000_11550	COG4481	Protein conserved in bacteria
JX000_11555	COG0668	transmembrane transport
JX000_11560	COG1475	DNA binding
JX000_11565	COG0626	cystathionine gamma-synthase activity
JX000_11570	COG0626	cystathionine gamma-synthase activity
JX000_11575	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JX000_11575	COG0646	methionine synthase
JX000_11580	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JX000_11595	COG3942	CHAP domain
JX000_11600	COG0640	Transcriptional regulator
JX000_11605	COG2814	Major facilitator Superfamily
JX000_11620	COG0210	DNA helicase
JX000_11630	COG0183	Belongs to the thiolase family
JX000_11665	COG1476	TRANSCRIPTIONal
JX000_11675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JX000_11695	COG1136	(ABC) transporter
JX000_11700	COG0577	efflux transmembrane transporter activity
JX000_11735	COG0577	efflux transmembrane transporter activity
JX000_11740	COG1136	(ABC) transporter
JX000_11775	COG1475	DNA binding
JX000_11780	COG0357	Ribosomal RNA small subunit methyltransferase G
JX000_11785	COG0445	tRNA wobble uridine modification
JX000_11790	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JX000_11795	COG0594	ribonuclease P activity
JX000_11815	COG0730	response to heat
JX000_11820	COG1937	Protein conserved in bacteria
JX000_11825	COG2210	Belongs to the sulfur carrier protein TusA family
JX000_11830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JX000_11845	COG1131	(ABC) transporter
JX000_11855	COG1063	alcohol dehydrogenase
JX000_11860	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JX000_11865	COG0693	protein deglycase activity
JX000_11880	COG0028	Belongs to the TPP enzyme family
JX000_11885	COG3527	Alpha-acetolactate decarboxylase
JX000_11890	COG1620	l-lactate permease
JX000_11895	COG0579	oxidoreductase
JX000_11905	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JX000_11940	COG1192	Involved in chromosome partitioning
JX000_12010	COG2217	Heavy metal translocating P-type atpase
JX000_12015	COG1937	Protein conserved in bacteria
JX000_12025	COG1230	cation diffusion facilitator family transporter
JX000_12030	COG0488	(ABC) transporter
JX000_12070	COG1611	Belongs to the LOG family