locus-tag	class	description
AOT14_00010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AOT14_00020	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AOT14_00030	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AOT14_00040	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AOT14_00060	ENOG4108K0D	peptidase, M48
AOT14_00120	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AOT14_00140	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AOT14_00160	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AOT14_00180	ENOG4105CGF	Aromatic amino acid aminotransferase
AOT14_00190	ENOG4105CHB	tonB-dependent Receptor
AOT14_00210	ENOG4108UHU	Aldolase
AOT14_00220	ENOG4105D7K	pfkb domain protein
AOT14_00230	ENOG4105D05	Receptor
AOT14_00270	ENOG4105EBR	Carboxylesterase
AOT14_00300	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AOT14_00320	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AOT14_00330	ENOG4105ETE	Transcriptional regulator (LacI family
AOT14_00340	ENOG4105CHR	reductase
AOT14_00360	ENOG4105EUJ	GTP cyclohydrolase i
AOT14_00410	ENOG4105K5B	UPF0225 protein
AOT14_00420	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
AOT14_00430	ENOG41067HS	methyltransferase
AOT14_00440	ENOG4105DSB	aldose 1-epimerase
AOT14_00450	ENOG4105DKK	Benzoate
AOT14_00530	ENOG41063SB	peptidase
AOT14_00540	ENOG4105CN1	protease
AOT14_00570	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
AOT14_00580	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
AOT14_00590	ENOG4105C26	Dehydrogenase
AOT14_00610	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
AOT14_00640	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
AOT14_00650	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
AOT14_00700	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AOT14_00710	ENOG4105DHU	Bile acid
AOT14_00730	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AOT14_00740	ENOG4107S2Z	UPF0761 membrane protein
AOT14_00750	ENOG4105KTH	gatB Yqey
AOT14_00760	ENOG4105VCC	30S ribosomal protein S21
AOT14_00770	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AOT14_00780	ENOG4107ZVW	dihydroneopterin aldolase
AOT14_00790	ENOG4105CUY	Mechanosensitive ion channel
AOT14_00800	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AOT14_00830	ENOG4107QJT	sodium dicarboxylate symporter
AOT14_00850	ENOG4106G6Q	Transcriptional regulator
AOT14_00870	ENOG4105DTQ	mandelate racemase muconate lactonizing
AOT14_00900	ENOG4108KPZ	tonB-dependent Receptor
AOT14_00900	ENOG4108KPZ	tonB-dependent Receptor
AOT14_00920	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
AOT14_00950	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
AOT14_00960	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AOT14_00970	ENOG4108UQS	dipeptidase
AOT14_01020	ENOG4105E32	cytoplasmic protein
AOT14_01040	ENOG4105BZS	acriflavin resistance protein
AOT14_01050	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AOT14_01060	ENOG4105CH2	amidohydrolase
AOT14_01070	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AOT14_01080	ENOG4109066	lysm domain bon superfamily protein
AOT14_01100	ENOG4105E9K	Isocitrate dehydrogenase
AOT14_01110	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
AOT14_01130	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AOT14_01140	ENOG4105K63	Thioredoxin
AOT14_01150	ENOG4105C1J	atp-dependent rna helicase
AOT14_01160	ENOG4105CAK	Cell division ATP-binding protein ftsE
AOT14_01170	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AOT14_01180	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AOT14_01190	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AOT14_01200	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AOT14_01240	ENOG4108TGY	Glutathione S-transferase
AOT14_01260	ENOG4105CWX	Alpha-1,2-mannosidase
AOT14_01270	ENOG4105ETE	Transcriptional regulator (LacI family
AOT14_01290	ENOG4105D7K	pfkb domain protein
AOT14_01350	ENOG4105ENE	Histidine kinase
AOT14_01380	ENOG4105C25	Primosomal protein n'
AOT14_01410	ENOG4107QI1	Mate efflux family protein
AOT14_01420	ENOG4105D07	Signal peptide peptidase, SppA
AOT14_01440	ENOG4107ZQV	short-chain dehydrogenase reductase
AOT14_01460	ENOG4105ETX	regulatoR
AOT14_01490	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AOT14_01500	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AOT14_01530	ENOG4108RPN	Protein smg homolog
AOT14_01540	ENOG4105C79	DNA protecting protein DprA
AOT14_01560	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AOT14_01570	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AOT14_01580	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AOT14_01600	ENOG4108SHN	Glycosyl transferase, family 2
AOT14_01670	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
AOT14_01690	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AOT14_01700	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AOT14_01710	ENOG4105CWX	Alpha-1,2-mannosidase
AOT14_01740	ENOG4108WUH	Transcriptional regulator, TetR family
AOT14_01770	ENOG4108ZHJ	Organic hydroperoxide resistance protein
AOT14_01800	ENOG4105CCI	Myosin-Cross-Reactive Antigen
AOT14_01810	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AOT14_01840	ENOG41088T4	Helicase IV
AOT14_01870	ENOG41065RQ	ADP-ribosylation crystallin J1
AOT14_01890	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AOT14_01960	ENOG4105C0D	helicase
AOT14_01990	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
AOT14_02040	ENOG4108NF7	phage-type endonuclease
AOT14_02070	ENOG4105W5Q	DNA repair protein (RadC
AOT14_02120	ENOG4108P8R	
AOT14_02210	ENOG4105CMM	transposase
AOT14_02250	ENOG4108VAC	response regulator
AOT14_02260	ENOG4108HRK	Histidine kinase
AOT14_02340	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AOT14_02380	ENOG4105EMN	RNA polymerase sigma factor
AOT14_02410	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
AOT14_02460	ENOG4107XTP	(EAL) domain protein
AOT14_02470	ENOG4105BZU	Histidine kinase
AOT14_02500	ENOG4105BZU	Histidine kinase
AOT14_02560	ENOG4108KPZ	tonB-dependent Receptor
AOT14_02590	ENOG4105GRZ	Ycii-related protein
AOT14_02600	ENOG4105GRZ	Ycii-related protein
AOT14_02630	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
AOT14_02640	ENOG4105CHP	RNA polymerase
AOT14_02660	ENOG4105C2F	Histidine kinase
AOT14_02670	ENOG4108VAC	response regulator
AOT14_02710	ENOG4105C9K	Endothelin-converting enzyme 1
AOT14_02740	ENOG4105CC0	LysR family Transcriptional regulator
AOT14_02750	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AOT14_02760	ENOG4105EEQ	Na H antiporter
AOT14_02810	ENOG4105ER2	Ompa motb domain protein
AOT14_02820	ENOG4107RD7	Flagellar Motor Protein, MotA
AOT14_02850	ENOG4105EW9	transcriptional regulator AsnC family
AOT14_02860	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AOT14_02890	ENOG4105BZU	Histidine kinase
AOT14_02900	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AOT14_02910	ENOG4105I08	Pseudouridine synthase
AOT14_02920	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
AOT14_02940	ENOG4108VPT	UPF0234 protein
AOT14_02960	ENOG4108EHX	EamA-like transporter family
AOT14_02970	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AOT14_02980	ENOG4108UMI	ABC transporter, permease
AOT14_02990	ENOG4105D01	(LipO)protein
AOT14_03030	ENOG4107QSN	dihydrolipoamide acetyltransferase
AOT14_03040	ENOG4107QN2	dihydrolipoyl dehydrogenase
AOT14_03070	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
AOT14_03080	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AOT14_03090	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AOT14_03100	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AOT14_03110	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AOT14_03120	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AOT14_03130	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AOT14_03140	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AOT14_03160	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AOT14_03180	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AOT14_03190	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AOT14_03230	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AOT14_03240	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AOT14_03250	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AOT14_03260	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AOT14_03270	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AOT14_03280	ENOG4105C19	ABC transporter
AOT14_03300	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AOT14_03320	ENOG4108YAB	Invasion protein
AOT14_03350	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AOT14_03420	ENOG4105E3B	Multicopper oxidase
AOT14_03450	ENOG4105DGW	oligopeptidase A
AOT14_03540	ENOG4108Z5K	methylglyoxal synthase
AOT14_03550	ENOG4105BZ8	glutamate synthase
AOT14_03560	ENOG4105CBC	glutamate synthase
AOT14_03630	ENOG4108I5C	dEAD DEAH box helicase
AOT14_03680	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AOT14_03690	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
AOT14_03700	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
AOT14_03760	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AOT14_03870	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AOT14_03890	ENOG4105M4E	phosphohistidine phosphatase, SixA
AOT14_03910	ENOG4107RZC	phospholipase d
AOT14_03940	ENOG4105KA0	thioesterase Superfamily protein
AOT14_03950	ENOG4105BZU	Histidine kinase
AOT14_04010	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AOT14_04020	ENOG4105C5F	glutamine synthetase
AOT14_04030	ENOG4108YZA	Nitrogen regulatory protein pii
AOT14_04040	ENOG4105BZU	Histidine kinase
AOT14_04050	ENOG4105CUX	Signal transduction histidine kinase
AOT14_04060	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AOT14_04070	ENOG4105D9P	serine threonine protein kinase
AOT14_04080	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AOT14_04090	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AOT14_04110	ENOG4105CHU	acetyl-coa acetyltransferase
AOT14_04200	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
AOT14_04210	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
AOT14_04220	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AOT14_04240	ENOG4107ZQV	short-chain dehydrogenase reductase
AOT14_04250	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
AOT14_04290	ENOG4105XUA	cytochrome c
AOT14_04300	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
AOT14_04330	ENOG4108HF7	Gcn5-related n-acetyltransferase
AOT14_04340	ENOG4105KWG	Pfam:DUF1696
AOT14_04400	ENOG4105F2I	Transposase
AOT14_04440	ENOG4105C01	Dihydroxy-acid dehydratase
AOT14_04460	ENOG4106032	Glutathionylspermidine synthase
AOT14_04500	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AOT14_04570	ENOG4108Z0R	Transferase
AOT14_04750	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AOT14_04760	ENOG4105MJ2	Competence protein
AOT14_04800	ENOG4105SUT	Transcriptional Regulator AraC Family
AOT14_04820	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AOT14_04850	ENOG4105C0B	DNA polymerase III (alpha subunit)
AOT14_04880	ENOG4105C0P	Mg chelatase subunit ChlI
AOT14_04910	ENOG4105F2I	Transposase
AOT14_05000	ENOG4108UQ8	endoribonuclease L-psp
AOT14_05010	ENOG4105CMU	LysR family (Transcriptional regulator
AOT14_05020	ENOG4105CX6	glutaminyL-tRNA synthetase
AOT14_05040	ENOG4105F2I	Transposase
AOT14_05050	ENOG4105BZU	Histidine kinase
AOT14_05060	ENOG4105F2I	Transposase
AOT14_05120	ENOG4107RFB	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AOT14_05130	ENOG4105CYM	Glutathione S-transferase
AOT14_05220	ENOG4105CHU	acetyl-coa acetyltransferase
AOT14_05240	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AOT14_05250	ENOG4105CIS	alcohol dehydrogenase
AOT14_05420	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AOT14_05500	ENOG4105C0P	Mg chelatase subunit ChlI
AOT14_05510	ENOG4105W0Z	cytoplasmic protein
AOT14_05520	ENOG4108YZA	Nitrogen regulatory protein pii
AOT14_05560	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AOT14_05570	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
AOT14_05580	ENOG4105EMU	Dehydrogenase
AOT14_05600	ENOG4105C75	arginyL-tRNA synthetase
AOT14_05610	ENOG4105W5Q	DNA repair protein (RadC
AOT14_05620	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AOT14_05630	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AOT14_05660	ENOG4105C08	Histidine kinase
AOT14_05670	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
AOT14_05680	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AOT14_05690	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AOT14_05720	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AOT14_05730	ENOG4105CGK	Exodeoxyribonuclease III
AOT14_05740	ENOG4105EYM	Major Facilitator superfamily
AOT14_05760	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AOT14_05770	ENOG4105DR5	peptidase
AOT14_05780	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AOT14_05860	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
AOT14_05870	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AOT14_05880	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AOT14_05890	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AOT14_05910	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
AOT14_05920	ENOG4108TGR	phosphatase
AOT14_05930	ENOG4108374	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
AOT14_05980	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
AOT14_05990	ENOG4105C1J	atp-dependent rna helicase
AOT14_06010	ENOG4108RXX	maleylacetoacetate isomerase
AOT14_06020	ENOG4105CZX	twitching motility protein
AOT14_06070	ENOG4105C28	cystathionine
AOT14_06090	ENOG4105GVR	general secretion pathway protein D
AOT14_06170	ENOG4108VAU	general secretion pathway protein G
AOT14_06190	ENOG4107QHF	type ii secretion system protein e
AOT14_06200	ENOG4105D7Q	type ii secretion system
AOT14_06220	ENOG4105EY8	ABC transporter
AOT14_06260	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AOT14_06300	ENOG4105CEY	Amp-dependent synthetase and ligase
AOT14_06310	ENOG4105CHR	reductase
AOT14_06350	ENOG4105C10	Electron transfer flavoprotein
AOT14_06360	ENOG4105BZJ	Electron transfer flavoprotein
AOT14_06390	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
AOT14_06400	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
AOT14_06420	ENOG4107QKV	phosphomannomutase
AOT14_06460	ENOG4105EYF	MMPL domain protein
AOT14_06490	ENOG4108NEV	two component transcriptional regulator, LytTR family
AOT14_06500	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AOT14_06530	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
AOT14_06550	ENOG4105CFP	Peptidase U32
AOT14_06560	ENOG4106RZ4	Peptidase U32
AOT14_06570	ENOG4108IYU	L-aspartate oxidase
AOT14_06660	ENOG4105WD1	Membrane
AOT14_06680	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AOT14_06700	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AOT14_06730	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AOT14_06740	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AOT14_06750	ENOG4108IG5	Transcriptional regulator
AOT14_06760	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AOT14_06770	ENOG4105BZS	acriflavin resistance protein
AOT14_06800	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AOT14_06810	ENOG4105CD8	aminopeptidase N
AOT14_06860	ENOG4105DFF	Rod shape-determining protein mreb
AOT14_06870	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AOT14_06890	ENOG4105CJN	penicillin-binding protein
AOT14_06900	ENOG4105CNI	cell division protein FtsW
AOT14_06910	ENOG4105CVE	Lytic murein transglycosylase
AOT14_06930	ENOG4105DZ1	carboxypeptidase
AOT14_06970	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AOT14_06980	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AOT14_06990	ENOG4105CN1	protease
AOT14_07020	ENOG4108J5G	6-phosphogluconate dehydrogenase
AOT14_07040	ENOG4105BZU	Histidine kinase
AOT14_07060	ENOG4105BZU	Histidine kinase
AOT14_07070	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AOT14_07110	ENOG41082W1	Cupin 2, conserved barrel domain protein
AOT14_07120	ENOG4105E2D	ec 3.2.1.52
AOT14_07130	ENOG4105EHZ	conserved protein UCP016719
AOT14_07140	ENOG4105E2D	ec 3.2.1.52
AOT14_07160	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AOT14_07170	ENOG4105E2D	ec 3.2.1.52
AOT14_07200	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AOT14_07210	ENOG4105EDR	glucose galactose transporter
AOT14_07220	ENOG4105ETE	Transcriptional regulator (LacI family
AOT14_07230	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AOT14_07240	ENOG4105CE4	GlcNAc 6-P deacetylase
AOT14_07270	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AOT14_07320	ENOG4108Z33	Thiol disulfide Interchange Protein
AOT14_07340	ENOG4106RE7	Cytochrome
AOT14_07350	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AOT14_07360	ENOG4105CY0	Metallo-Beta-Lactamase
AOT14_07400	ENOG4108RXX	maleylacetoacetate isomerase
AOT14_07460	ENOG4105C4W	S-formylglutathione hydrolase
AOT14_07500	ENOG4108RMV	DegV Family
AOT14_07510	ENOG4105CI2	imidazolone-5-propionate hydrolase
AOT14_07520	ENOG41069H0	dihydroorotase EC 3.5.2.3
AOT14_07560	ENOG4105C1J	atp-dependent rna helicase
AOT14_07600	ENOG4105CHM	Aminotransferase
AOT14_07610	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AOT14_07630	ENOG4105FQP	Beta-lactamase
AOT14_07640	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AOT14_07660	ENOG4106KR7	LysR family Transcriptional regulator
AOT14_07670	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AOT14_07680	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AOT14_07700	ENOG4105ENH	Sulfatase
AOT14_07710	ENOG4105C4X	radical SAM domain protein
AOT14_07720	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AOT14_07730	ENOG4105D6U	Sodium Glutamate Symporter
AOT14_07760	ENOG4106KNT	transcriptional regulator
AOT14_07790	ENOG4105C6K	Malic enzyme
AOT14_07850	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AOT14_07870	ENOG4105D1S	lipid A biosynthesis
AOT14_07880	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AOT14_07890	ENOG4105DFG	type I secretion outer membrane protein
AOT14_07900	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AOT14_07930	ENOG4105BZS	acriflavin resistance protein
AOT14_07940	ENOG4105BZU	Histidine kinase
AOT14_08000	ENOG4105C2M	dna polymerase I
AOT14_08010	ENOG41069NU	Nitroreductase
AOT14_08030	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AOT14_08070	ENOG4105W8H	transhydrogenase (subunit alpha
AOT14_08090	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AOT14_08120	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AOT14_08130	ENOG4108Z66	YbaK ebsC protein
AOT14_08160	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AOT14_08170	ENOG4107S2Z	UPF0761 membrane protein
AOT14_08180	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AOT14_08190	ENOG4105CSR	polyphosphate kinase 2
AOT14_08240	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AOT14_08250	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AOT14_08260	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
AOT14_08280	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AOT14_08300	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AOT14_08320	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AOT14_08330	ENOG4105C3G	gtp-binding protein
AOT14_08340	ENOG4105D05	Receptor
AOT14_08350	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
AOT14_08360	ENOG4105D44	asparaginase
AOT14_08400	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AOT14_08420	ENOG4105PM1	preprotein translocase subunit SecE
AOT14_08430	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AOT14_08440	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AOT14_08450	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AOT14_08460	ENOG4108VZM	50s ribosomal protein L10
AOT14_08470	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AOT14_08480	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AOT14_08490	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AOT14_08500	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AOT14_08510	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AOT14_08520	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AOT14_08530	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AOT14_08550	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AOT14_08560	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AOT14_08570	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AOT14_08580	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AOT14_08590	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AOT14_08600	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AOT14_08610	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AOT14_08620	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AOT14_08630	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AOT14_08650	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AOT14_08660	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AOT14_08670	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AOT14_08680	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AOT14_08690	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AOT14_08700	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AOT14_08710	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AOT14_08720	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AOT14_08730	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AOT14_08740	ENOG41087MT	50S ribosomal protein L30
AOT14_08750	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AOT14_08760	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AOT14_08770	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AOT14_08780	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AOT14_08790	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AOT14_08800	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AOT14_08810	ENOG4108ZT0	50S ribosomal protein l17
AOT14_08820	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
AOT14_08830	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
AOT14_08850	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AOT14_08880	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
AOT14_08890	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AOT14_08900	ENOG4105D3G	Pseudouridine synthase
AOT14_08910	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AOT14_08940	ENOG4105BZU	Histidine kinase
AOT14_08950	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AOT14_08960	ENOG4105E0X	reductase
AOT14_08980	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AOT14_08990	ENOG4108K3A	Glutathione S-transferase
AOT14_09010	ENOG4105F2I	Transposase
AOT14_09020	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AOT14_09040	ENOG4105CDV	Ompa motb domain protein
AOT14_09060	ENOG4105FE9	pseudouridine synthase
AOT14_09080	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AOT14_09100	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
AOT14_09110	ENOG4108I5D	sulfate abc transporter
AOT14_09130	ENOG4108IJ6	ABC transporter
AOT14_09160	ENOG4105CPQ	Dehydrogenase
AOT14_09190	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AOT14_09210	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AOT14_09240	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AOT14_09250	ENOG4105ED9	Protein of unknown function (DUF455)
AOT14_09280	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AOT14_09300	ENOG4105BZF	Glycosyl transferase (Group 1
AOT14_09310	ENOG4105C9X	ppx gppa phosphatase
AOT14_09320	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AOT14_09330	ENOG4105BZU	Histidine kinase
AOT14_09340	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AOT14_09350	ENOG4105ERG	peptidase m48, ste24p
AOT14_09360	ENOG4105VW4	glutaredoxin 3
AOT14_09380	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AOT14_09460	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AOT14_09470	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AOT14_09480	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AOT14_09550	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
AOT14_09560	ENOG41068JE	domain protein
AOT14_09570	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AOT14_09600	ENOG4107RZZ	dna polymerase iii epsilon subunit
AOT14_09610	ENOG4108ZF3	Phosphatase
AOT14_09650	ENOG4105DKP	glycosyl transferase, family 9
AOT14_09660	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
AOT14_09670	ENOG4107UV6	ribonuclease Z
AOT14_09690	ENOG4105DFP	Integrase
AOT14_09730	ENOG4108ZD2	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division (By similarity)
AOT14_09760	ENOG4105C0B	DNA polymerase III (alpha subunit)
AOT14_09850	ENOG4108NF7	phage-type endonuclease
AOT14_09890	ENOG4105F9F	transposase
AOT14_09990	ENOG4105F2I	Transposase
AOT14_10080	ENOG4105F2I	Transposase
AOT14_10110	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AOT14_10120	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AOT14_10140	ENOG4105K59	histidine triad (HIT) protein
AOT14_10190	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AOT14_10210	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
AOT14_10240	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
AOT14_10250	ENOG4105VGS	50s ribosomal protein l32
AOT14_10260	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AOT14_10280	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AOT14_10290	ENOG4105CHR	reductase
AOT14_10310	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AOT14_10330	ENOG4105HHA	aminodeoxychorismate lyase
AOT14_10340	ENOG4107QRG	dna polymerase iii
AOT14_10380	ENOG4105DGI	Alkaline phosphatase
AOT14_10440	ENOG4105II7	pyrroline-5-carboxylate reductase
AOT14_10450	ENOG4105CZX	twitching motility protein
AOT14_10460	ENOG4105CZX	twitching motility protein
AOT14_10500	ENOG4108R3E	Dna-3-methyladenine glycosylase i
AOT14_10510	ENOG4108UJU	UPF0301 protein
AOT14_10520	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AOT14_10530	ENOG4105CXT	aspartate transcarbamylase
AOT14_10560	ENOG4105CJW	magnesium transporter
AOT14_10570	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AOT14_10600	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AOT14_10610	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
AOT14_10620	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
AOT14_10630	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
AOT14_10640	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AOT14_10650	ENOG4108IUZ	ABC transporter
AOT14_10690	ENOG4105C2X	Arabinose 5-phosphate isomerase
AOT14_10710	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AOT14_10730	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOT14_10740	ENOG4105C34	Pseudouridine synthase
AOT14_10770	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
AOT14_10790	ENOG4105BZP	glycoside hydrolase 15-related
AOT14_10800	ENOG4108K4C	ec 3.1.3.12
AOT14_10810	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AOT14_10860	ENOG4105E18	UPF0276 protein
AOT14_10880	ENOG4105CA0	peroxidase
AOT14_10900	ENOG4105PE1	Receptor
AOT14_10920	ENOG4108SF5	RNA Polymerase
AOT14_10930	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AOT14_10960	ENOG4105CR8	Transcriptional regulator
AOT14_10970	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AOT14_10980	ENOG4107RNH	Outer membrane receptor FepA
AOT14_10990	ENOG4105C5H	ABC transporter
AOT14_11000	ENOG4105ETT	transcriptional Regulator, LysR family
AOT14_11030	ENOG4107QPV	Serine Threonine protein kinase
AOT14_11060	ENOG4105C9M	aspartyl-trna synthetase
AOT14_11100	ENOG4105D05	Receptor
AOT14_11120	ENOG4105CDY	transcriptional regulatory protein
AOT14_11130	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AOT14_11140	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AOT14_11150	ENOG4105DFH	Transport of potassium into the cell (By similarity)
AOT14_11160	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AOT14_11170	ENOG4107YD3	Thioesterase
AOT14_11180	ENOG4105E02	MotA TolQ exbB proton channel
AOT14_11190	ENOG4105SG9	biopolymer transport protein, ExbD
AOT14_11220	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AOT14_11240	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AOT14_11280	ENOG4108DT4	serine threonine protein kinase
AOT14_11290	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AOT14_11310	ENOG4105CQ7	ATP-dependent helicase
AOT14_11340	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AOT14_11370	ENOG4105BZ4	penicillin-binding protein
AOT14_11390	ENOG4105DVT	helicase
AOT14_11400	ENOG41072GX	Peptidase M22 Glycoprotease
AOT14_11420	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AOT14_11440	ENOG4105CFH	Aspartokinase
AOT14_11460	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AOT14_11480	ENOG4105EAH	synthase
AOT14_11490	ENOG4105CG3	alpha amylase, catalytic region
AOT14_11520	ENOG4107RBJ	symporter
AOT14_11580	ENOG4108UUM	single-stranded DNA-binding protein
AOT14_11600	ENOG4105CAU	Arsenical resistance protein, ArsH
AOT14_11630	ENOG4105D6J	arsenicaL-resistance protein
AOT14_11650	ENOG4106S2D	Transcriptional regulator
AOT14_11670	ENOG4107S8C	mandelate racemase muconate lactonizing
AOT14_11690	ENOG4105D05	Receptor
AOT14_11710	ENOG4105DUX	Transporter
AOT14_11720	ENOG4105EPD	Oligopeptide transporter, Opt family
AOT14_11730	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AOT14_11760	ENOG4105VCD	cytoplasmic protein
AOT14_11770	ENOG4105D22	carbon starvation protein
AOT14_11780	ENOG4105EUB	pirin domain protein
AOT14_11800	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AOT14_11810	ENOG4105EUB	pirin domain protein
AOT14_11820	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
AOT14_11830	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AOT14_11890	ENOG4105C9K	Endothelin-converting enzyme 1
AOT14_11910	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AOT14_11920	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AOT14_11930	ENOG4108JA2	transcriptioN-repair coupling factor
AOT14_11950	ENOG4105D6S	protein involved in catabolism of external DNA
AOT14_11960	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AOT14_11970	ENOG4105EB3	Histidine kinase
AOT14_11980	ENOG4105BZU	Histidine kinase
AOT14_11990	ENOG4105CT7	inner membrane cred family protein
AOT14_12050	ENOG4108TGP	Thioesterase superfamily protein
AOT14_12060	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AOT14_12070	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AOT14_12080	ENOG4105K46	50S ribosomal protein l27
AOT14_12100	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AOT14_12120	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AOT14_12130	ENOG4105CJR	Integral membrane protein (MviN
AOT14_12160	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AOT14_12170	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AOT14_12180	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AOT14_12210	ENOG4105F2I	Transposase
AOT14_12310	ENOG4105D05	Receptor
AOT14_12350	ENOG4105E2S	oxidase) subunit II
AOT14_12360	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AOT14_12370	ENOG4105CCU	oxidase (Subunit III)
AOT14_12380	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
AOT14_12390	ENOG4105BZU	Histidine kinase
AOT14_12400	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AOT14_12430	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AOT14_12440	ENOG4105EA8	2-Nitropropane dioxygenase
AOT14_12460	ENOG4105K5M	30s ribosomal protein S16
AOT14_12470	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AOT14_12480	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AOT14_12490	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AOT14_12500	ENOG4105E98	transcriptional regulator DeoR family
AOT14_12510	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
AOT14_12520	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
AOT14_12530	ENOG4105E70	isomerase
AOT14_12560	ENOG4105EPC	oxidoreductase
AOT14_12570	ENOG4107QJQ	Mate efflux family protein
AOT14_12590	ENOG4105VEJ	Heat shock protein
AOT14_12610	ENOG4105CH6	catalase
AOT14_12630	ENOG4108Z3G	3H domain protein
AOT14_12680	ENOG4105BZU	Histidine kinase
AOT14_12690	ENOG4107ZT5	Thiol disulfide interchange protein
AOT14_12700	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
AOT14_12750	ENOG4105C59	p-type ATPase
AOT14_12790	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
AOT14_12820	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
AOT14_12830	ENOG41090JD	Blue (Type 1) copper domain protein
AOT14_12840	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AOT14_12850	ENOG4105EMN	RNA polymerase sigma factor
AOT14_12870	ENOG4105C0H	protease
AOT14_12880	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AOT14_12890	ENOG4105C3F	Signal peptidase i
AOT14_12910	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AOT14_12920	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AOT14_12930	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
AOT14_12950	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AOT14_12960	ENOG41080ZE	Adenylate cyclase
AOT14_12970	ENOG4107ZXU	DSBA oxidoreductase
AOT14_12980	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AOT14_12990	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AOT14_13000	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
AOT14_13010	ENOG4105VEQ	Cold shock protein
AOT14_13020	ENOG41061H0	Monooxygenase
AOT14_13070	ENOG4105CMM	transposase
AOT14_13090	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AOT14_13090	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AOT14_13120	ENOG4105CSU	acyl-Coa dehydrogenase
AOT14_13150	ENOG4105CHU	acetyl-coa acetyltransferase
AOT14_13180	ENOG4105D5P	Methylmalonyl-coA mutase
AOT14_13190	ENOG4105BZU	Histidine kinase
AOT14_13200	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
AOT14_13210	ENOG4105CI2	imidazolone-5-propionate hydrolase
AOT14_13220	ENOG4105E2D	ec 3.2.1.52
AOT14_13230	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AOT14_13240	ENOG4105E0F	Histidine kinase
AOT14_13250	ENOG4105BZU	Histidine kinase
AOT14_13260	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
AOT14_13270	ENOG4105BZU	Histidine kinase
AOT14_13280	ENOG4106HNH	Acyl-transferase
AOT14_13330	ENOG4105CZM	Major Facilitator
AOT14_13360	ENOG4107RZC	phospholipase d
AOT14_13370	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
AOT14_13410	ENOG4108VKG	metal-dependent hydrolase
AOT14_13430	ENOG4105KSC	Transcriptional regulator, TraR DksA family
AOT14_13500	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AOT14_13590	ENOG4105M4H	endoribonuclease L-psp
AOT14_13600	ENOG4106BRA	Membrane
AOT14_13640	ENOG4105RA2	Membrane
AOT14_13650	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AOT14_13670	ENOG4105CSH	Transporter
AOT14_13680	ENOG4105W3S	hemerythrin-like, metal-binding protein
AOT14_13690	ENOG4105BZU	Histidine kinase
AOT14_13700	ENOG4105ETX	regulatoR
AOT14_13760	ENOG4105CJP	fad dependent oxidoreductase
AOT14_13780	ENOG4107RUE	extracellular solute-binding protein family 1
AOT14_13790	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AOT14_13800	ENOG4105F38	ABC transporter, permease
AOT14_13810	ENOG4105D38	putrescine abc transporter
AOT14_13820	ENOG4105C26	Dehydrogenase
AOT14_13860	ENOG4108JU5	Magnesium and cobalt efflux protein
AOT14_13890	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AOT14_13910	ENOG4105C9A	Phoh family
AOT14_13920	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
AOT14_13940	ENOG4105CJ1	ABC, transporter
AOT14_13950	ENOG4105CJ1	ABC, transporter
AOT14_13960	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AOT14_13970	ENOG4105E4C	Lytic transglycosylase catalytic
AOT14_13980	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AOT14_13990	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AOT14_14000	ENOG4105EIX	cytochrome c1
AOT14_14010	ENOG4107MKT	Stringent starvation protein a
AOT14_14020	ENOG4105KB2	stringent starvation protein b
AOT14_14050	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AOT14_14070	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AOT14_14080	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AOT14_14090	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AOT14_14100	ENOG4105M2J	Glutaredoxin
AOT14_14110	ENOG4105E1F	short-chain dehydrogenase reductase
AOT14_14120	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
AOT14_14130	ENOG4108KPZ	tonB-dependent Receptor
AOT14_14140	ENOG4105EWT	decarboxylase family
AOT14_14150	ENOG4108HRK	Histidine kinase
AOT14_14240	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AOT14_14260	ENOG4105C22	threonyL-tRNA synthetase
AOT14_14270	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AOT14_14280	ENOG41082NX	50s ribosomal protein l35
AOT14_14290	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AOT14_14300	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AOT14_14310	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AOT14_14320	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AOT14_14360	ENOG4105C58	cytochrome c oxidase accessory protein ccog
AOT14_14390	ENOG4105D4P	Coproporphyrinogen iii oxidase
AOT14_14410	ENOG4107QQG	Dehydrogenase
AOT14_14420	ENOG4105CBC	glutamate synthase
AOT14_14430	ENOG4105BZ8	glutamate synthase
AOT14_14460	ENOG4105C72	UPF0176 protein
AOT14_14470	ENOG4105DEN	Luciferase family
AOT14_14510	ENOG4105CJ3	phosphate transporter
AOT14_14530	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AOT14_14560	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AOT14_14570	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AOT14_14590	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AOT14_14600	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AOT14_14610	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AOT14_14620	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AOT14_14630	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AOT14_14640	ENOG4108DG9	Smr protein MutS2
AOT14_14650	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AOT14_14660	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AOT14_14670	ENOG4108UM1	dedA family
AOT14_14680	ENOG4108K5P	(LipO)protein
AOT14_14710	ENOG4105HBR	Rna-binding protein
AOT14_14720	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AOT14_14730	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AOT14_14750	ENOG4105EEI	dihydropteroate synthase
AOT14_14760	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AOT14_14770	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AOT14_14780	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AOT14_14810	ENOG4105DJ4	phosphatidylserine decarboxylase
AOT14_14830	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AOT14_14850	ENOG4105C5I	Dehydrogenase
AOT14_14860	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AOT14_14890	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AOT14_14900	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AOT14_14940	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AOT14_14950	ENOG4105EXC	Acyl-transferase
AOT14_14960	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AOT14_14970	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AOT14_14980	ENOG4107BJW	polysaccharide deacetylase
AOT14_15020	ENOG4105CP7	Triose-phosphate isomerase
AOT14_15050	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AOT14_15060	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AOT14_15070	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AOT14_15080	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AOT14_15100	ENOG4107QIZ	NADH dehydrogenase
AOT14_15110	ENOG4107R0R	NADH dehydrogenase subunit g
AOT14_15130	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AOT14_15140	ENOG4105DF2	NADH dehydrogenase subunit j
AOT14_15170	ENOG4105C8S	subunit m
AOT14_15180	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AOT14_15200	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AOT14_15210	ENOG4105CHV	Transcription elongation factor NusA
AOT14_15220	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AOT14_15230	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AOT14_15250	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AOT14_15260	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AOT14_15270	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
AOT14_15280	ENOG4108PAU	MotA TolQ exbB proton channel
AOT14_15290	ENOG4105M15	transport protein ExbD
AOT14_15300	ENOG4105BZ1	(ABC) transporter
AOT14_15310	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AOT14_15320	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AOT14_15350	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AOT14_15440	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AOT14_15460	ENOG4105CSU	acyl-Coa dehydrogenase
AOT14_15480	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AOT14_15500	ENOG4108S3W	Anti-feci sigma factor, fecr
AOT14_15510	ENOG4105CI2	imidazolone-5-propionate hydrolase
AOT14_15520	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
AOT14_15530	ENOG4105QNF	Outer membrane lipoprotein
AOT14_15550	ENOG4105BZU	Histidine kinase
AOT14_15560	ENOG4105EQ2	LysR family Transcriptional regulator
AOT14_15570	ENOG4105ENX	hydrolase
AOT14_15600	ENOG4105E6M	Sulphatase-modifying factor protein
AOT14_15620	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AOT14_15630	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AOT14_15640	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AOT14_15650	ENOG4105K8N	protein family UPF0079, ATPase
AOT14_15660	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AOT14_15670	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AOT14_15720	ENOG4105CHR	reductase
AOT14_15730	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AOT14_15740	ENOG4105D0M	Protease HtpX homolog
AOT14_15780	ENOG4105BZU	Histidine kinase
AOT14_15790	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
AOT14_15800	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AOT14_15820	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AOT14_15840	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AOT14_15900	ENOG4105CD3	dihydroorotase
AOT14_15920	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AOT14_15940	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
AOT14_15950	ENOG4105C8N	cysteinyl-tRNA synthetase
AOT14_15980	ENOG4105DBV	ornithine carbamoyltransferase
AOT14_15990	ENOG4105CDH	Citrulline--aspartate ligase
AOT14_16010	ENOG4105CAS	nag kinase
AOT14_16040	ENOG4105CH7	arginosuccinase
AOT14_16120	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AOT14_16130	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AOT14_16140	ENOG4108JJ9	ABC, transporter
AOT14_16150	ENOG4108JJ8	(ABC) transporter
AOT14_16170	ENOG4105DWV	Homoserine O-trans-acetylase
AOT14_16190	ENOG4106FI7	cytochrome c-type biogenesis protein
AOT14_16200	ENOG4105KWW	Biogenesis protein
AOT14_16210	ENOG4107QX9	Thiol disulfide interChange protein
AOT14_16220	ENOG4105DA4	cytochrome c-type biogenesis protein
AOT14_16230	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AOT14_16250	ENOG41060IM	Heme exporter protein
AOT14_16270	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
AOT14_16280	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
AOT14_16290	ENOG4105CHM	Aminotransferase
AOT14_16330	ENOG4105FE9	pseudouridine synthase
AOT14_16340	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AOT14_16350	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AOT14_16360	ENOG4105K9H	YciI-like protein
AOT14_16380	ENOG4105ETE	Transcriptional regulator (LacI family
AOT14_16390	ENOG4108KPZ	tonB-dependent Receptor
AOT14_16430	ENOG4105DRS	transport system, permease
AOT14_16460	ENOG4108UHU	Aldolase
AOT14_16470	ENOG4105C01	Dihydroxy-acid dehydratase
AOT14_16490	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AOT14_16520	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
AOT14_16570	ENOG4105E33	succinate dehydrogenase
AOT14_16580	ENOG410681N	tpr repeat protein
AOT14_16600	ENOG4105D60	lipoprotein releasing system transmembrane protein
AOT14_16630	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
AOT14_16640	ENOG4105CEN	a g-specific adenine glycosylase
AOT14_16650	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AOT14_16670	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AOT14_16680	ENOG4106H78	methyltransferase
AOT14_16690	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AOT14_16710	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AOT14_16720	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AOT14_16740	ENOG4105DKK	Benzoate
AOT14_16750	ENOG4105DFA	alanine racemase domain protein
AOT14_16760	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AOT14_16770	ENOG4105C8F	Beta-lactamase domain protein
AOT14_16800	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AOT14_16810	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AOT14_16850	ENOG4105CC0	LysR family Transcriptional regulator
AOT14_16910	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AOT14_16930	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AOT14_16940	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AOT14_16950	ENOG4105VIE	preprotein translocase, subunit YajC
AOT14_16960	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AOT14_16970	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AOT14_16980	ENOG4105RKW	reductase (By
AOT14_16990	ENOG4105BZU	Histidine kinase
AOT14_17000	ENOG4105CBX	hi0933 family
AOT14_17010	ENOG4108VWS	Yaeq family
AOT14_17020	ENOG4108UPT	UPF0178 protein
AOT14_17040	ENOG4105VEQ	Cold shock protein
AOT14_17050	ENOG4105CNG	UPF0061 protein
AOT14_17060	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AOT14_17070	ENOG4105C1J	atp-dependent rna helicase
AOT14_17080	ENOG4105HMI	Membrane
AOT14_17090	ENOG4105DUM	transcriptional regulator, lysR family
AOT14_17100	ENOG4105C5H	ABC transporter
AOT14_17140	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AOT14_17160	ENOG4105DUX	Transporter
AOT14_17210	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AOT14_17220	ENOG4105DGW	oligopeptidase A
AOT14_17230	ENOG4108V06	Glutathione peroxidase
AOT14_17250	ENOG4105DP0	ferredoxin-NADP reductase
AOT14_17280	ENOG4105EN6	Membrane
AOT14_17290	ENOG4107ZT3	family UPF0126
AOT14_17300	ENOG4107GFK	fumarate
AOT14_17340	ENOG4105K89	arsenate reductase
AOT14_17350	ENOG4105HDD	phospholipase
AOT14_17380	ENOG4105VEQ	Cold shock protein
AOT14_17410	ENOG4105CUZ	uba thif-type nad fad binding protein
AOT14_17420	ENOG4105EYA	deoxyribonuclease
AOT14_17460	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AOT14_17490	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AOT14_17500	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AOT14_17520	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
AOT14_17530	ENOG4105M0Y	
AOT14_17560	ENOG4105BZM	domain protein
AOT14_17670	ENOG4105GTG	Isochorismatase
AOT14_17700	ENOG4105DQE	DNA ligase
AOT14_17710	ENOG4105K3G	Periplasmic Protein
AOT14_17780	ENOG4105EQ2	LysR family Transcriptional regulator
AOT14_17790	ENOG4105DQ4	alcohol dehydrogenase
AOT14_17800	ENOG4105CH2	amidohydrolase
AOT14_17810	ENOG4105NCT	RNA Polymerase
AOT14_17820	ENOG4108ZJD	Protein of unknown function (DUF1109)
AOT14_17920	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT14_17930	ENOG4105BZU	Histidine kinase
AOT14_17940	ENOG4105FQP	Beta-lactamase
AOT14_18120	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AOT14_18230	ENOG41088SP	formiminoglutamate hydrolase
AOT14_18240	ENOG4105C84	Histidine ammonia-lyase
AOT14_18250	ENOG4105CGP	Urocanate hydratase
AOT14_18260	ENOG4105CZE	histidine utilization repressor
AOT14_18270	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AOT14_18290	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
AOT14_18320	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AOT14_18340	ENOG4108IJF	Heavy metal efflux pump, CzcA
AOT14_18350	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
AOT14_18500	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AOT14_18520	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
AOT14_18530	ENOG4105CY0	Metallo-Beta-Lactamase
AOT14_18540	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AOT14_18600	ENOG4105GR3	Histidine kinase
AOT14_18710	ENOG4105YPM	F pilin acetylation protein TraX
AOT14_18750	ENOG4105F2I	Transposase
AOT14_18960	ENOG4108VAC	response regulator
AOT14_19030	ENOG4105F2I	Transposase
AOT14_19080	ENOG4106N3A	copper homeostasis protein cutc
AOT14_19100	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AOT14_19110	ENOG4107Z6W	Protein CrcB homolog
AOT14_19120	ENOG4105D1H	recombination factor protein RarA
AOT14_19130	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
AOT14_19140	ENOG4105CNU	cell division protein FtsK
AOT14_19150	ENOG4105C3M	thioredoxin reductase
AOT14_19160	ENOG4105DIN	metallophosphoesterase
AOT14_19210	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AOT14_19220	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AOT14_19230	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AOT14_19260	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AOT14_19270	ENOG41075W9	High frequency lysogenization protein HflD homolog
AOT14_19300	ENOG4105BZU	Histidine kinase
AOT14_19320	ENOG4105BZU	Histidine kinase
AOT14_19330	ENOG4105BZU	Histidine kinase
AOT14_19370	ENOG4107R88	Chemotaxis protein (CheV)
AOT14_19390	ENOG4108ZC9	flagellar basal-body rod protein flgc
AOT14_19400	ENOG4105W00	Flagellar hook capping protein
AOT14_19410	ENOG4105BZE	flagellar hook protein, FlgE
AOT14_19420	ENOG4108KPB	Flagellar basal-body rod protein FlgF
AOT14_19430	ENOG4105CGA	flagellar basal-body rod protein FlgG
AOT14_19440	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AOT14_19450	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AOT14_19460	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AOT14_19470	ENOG4105E1Q	flagellar hook-associated protein
AOT14_19480	ENOG4105DTJ	flagellar hook-associated protein
AOT14_19510	ENOG4105DTS	flagellar hook-associated
AOT14_19520	ENOG4105MQ3	flagellar protein FliS
AOT14_19560	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AOT14_19570	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AOT14_19580	ENOG4108JUA	Transcriptional regulator
AOT14_19610	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
AOT14_19680	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AOT14_19690	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AOT14_19710	ENOG4108JIR	Flagellum-specific ATP synthase
AOT14_19750	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AOT14_19760	ENOG4105DD5	Flagellar motor switch protein
AOT14_19770	ENOG4105K0P	flagellar biosynthesis protein
AOT14_19780	ENOG4105CN7	Flagellar biosynthetic protein FliP
AOT14_19790	ENOG4105VS8	Flagellar biosynthetic protein fliq
AOT14_19800	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
AOT14_19810	ENOG4105BZU	Histidine kinase
AOT14_19820	ENOG4105D00	flagellar biosynthetic protein flhB
AOT14_19830	ENOG4105D7B	Flagellar biosynthesis protein flha
AOT14_19840	ENOG4105FZW	flagellar biosynthesis regulator FlhF
AOT14_19850	ENOG4107R21	site-determining protein
AOT14_19860	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AOT14_19870	ENOG4108VYJ	response regulator receiver protein
AOT14_19890	ENOG4105CBS	Chea signal transduction histidine kinase
AOT14_19900	ENOG4105E14	MotA TolQ exbB proton channel
AOT14_19910	ENOG4106VK6	Flagellar motor protein
AOT14_19930	ENOG4108V3W	Chemotaxis protein, CheW
AOT14_19950	ENOG4108VYJ	response regulator receiver protein
AOT14_19960	ENOG4105CBS	Chea signal transduction histidine kinase
AOT14_19980	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT14_19990	ENOG4108REP	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity)
AOT14_20000	ENOG4108V3W	Chemotaxis protein, CheW
AOT14_20020	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT14_20030	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT14_20030	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT14_20040	ENOG4105BZU	Histidine kinase
AOT14_20050	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
AOT14_20060	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AOT14_20070	ENOG4105BZU	Histidine kinase
AOT14_20080	ENOG4105DFA	alanine racemase domain protein
AOT14_20130	ENOG4105C84	Histidine ammonia-lyase
AOT14_20230	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
AOT14_20250	ENOG4105BZU	Histidine kinase
AOT14_20300	ENOG4105E39	Enoyl-CoA hydratase
AOT14_20310	ENOG4105BZU	Histidine kinase
AOT14_20320	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AOT14_20330	ENOG4105CRK	lysyL-tRNA synthetase
AOT14_20340	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AOT14_20370	ENOG4105DY0	carbon monoxide dehydrogenase operon C protein
AOT14_20390	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AOT14_20410	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AOT14_20420	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AOT14_20440	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AOT14_20450	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AOT14_20460	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
AOT14_20480	ENOG4105CE1	Ferrous iron transport protein b
AOT14_20510	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
AOT14_20550	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AOT14_20590	ENOG4105CQB	FAD linked oxidase domain protein
AOT14_20600	ENOG4108JQ1	Dehydrogenase
AOT14_20620	ENOG4105CUB	amino acid
AOT14_20630	ENOG4105CUB	amino acid
AOT14_20640	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
AOT14_20650	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
AOT14_20660	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
AOT14_20670	ENOG4108302	MgtC SapB transporter
AOT14_20700	ENOG4105D5Q	Arginine ornithine antiporter
AOT14_20770	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AOT14_20780	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AOT14_20790	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AOT14_20800	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AOT14_20810	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AOT14_20820	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AOT14_20830	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AOT14_20840	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AOT14_20860	ENOG4105CUT	histidyl-tRNA synthetase
AOT14_20870	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
AOT14_20890	ENOG4105D98	threonine synthase
AOT14_20950	ENOG4105C26	Dehydrogenase
AOT14_20980	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AOT14_20990	ENOG4105D4A	Cell wall formation (By similarity)
AOT14_21170	ENOG4106NZI	LysR family Transcriptional regulator
AOT14_21200	ENOG41081QV	Universal stress protein
AOT14_21210	ENOG4105CHR	reductase
AOT14_21230	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
AOT14_21240	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
AOT14_21270	ENOG4105CJ1	ABC, transporter
AOT14_21280	ENOG4107QWP	ABC-2 type transporter
AOT14_21290	ENOG4107QWP	ABC-2 type transporter
AOT14_21320	ENOG4105CY0	Metallo-Beta-Lactamase
AOT14_21330	ENOG4105EWT	decarboxylase family
AOT14_21370	ENOG4107QRI	Phosphoketolase
AOT14_21420	ENOG4107QJE	Chromosome Partitioning Protein
AOT14_21430	ENOG4105F2I	Transposase
AOT14_21590	ENOG4108YGG	dna repair protein
AOT14_21620	ENOG4105DFP	Integrase
AOT14_21630	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AOT14_21640	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AOT14_21650	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AOT14_21660	ENOG4105D06	uba thif-type nad fad binding protein
AOT14_21670	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AOT14_21680	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AOT14_21700	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
AOT14_21720	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AOT14_21730	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AOT14_21760	ENOG4105CHU	acetyl-coa acetyltransferase
AOT14_21770	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AOT14_21790	ENOG4105ESV	Glycosyl transferase, family 4
AOT14_21800	ENOG4105CFV	Tetratricopeptide repeat protein
AOT14_21820	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AOT14_21830	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AOT14_21840	ENOG4105CAT	Cytidine monophosphate kinase
AOT14_21850	ENOG4105YK5	50S ribosomal protein L36
AOT14_21870	ENOG4105DWY	Agmatine deiminase
AOT14_21990	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
AOT14_22000	ENOG41090A4	Pterin carbinolamine dehydratase
AOT14_22020	ENOG4105EI2	Pseudouridine synthase
AOT14_22030	ENOG4105C03	ribonuclease
AOT14_22040	ENOG4105WH1	Two component transcriptional regulator luxr family
AOT14_22050	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AOT14_22060	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AOT14_22080	ENOG4108UYB	regulatoR
AOT14_22090	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
AOT14_22100	ENOG4107QIJ	Aconitate hydratase 2
AOT14_22130	ENOG4107QM5	aconitate hydratase
AOT14_22150	ENOG4105CDU	Replicative dna helicase
AOT14_22170	ENOG4105CAQ	asparagine synthetase
AOT14_22180	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AOT14_22190	ENOG4108TGY	Glutathione S-transferase
AOT14_22220	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AOT14_22230	ENOG4108Z6B	deaminase
AOT14_22260	ENOG4105CC0	LysR family Transcriptional regulator
AOT14_22270	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AOT14_22320	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AOT14_22360	ENOG4107RGH	Aldehyde dehydrogenase
AOT14_22370	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AOT14_22400	ENOG4108ZX5	transcriptional regulator
AOT14_22410	ENOG4107QP8	phosphohexose isomerase
AOT14_22420	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AOT14_22430	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AOT14_22440	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AOT14_22450	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AOT14_22460	ENOG4105DJ0	Poly(A) Polymerase
AOT14_22480	ENOG4108Z4U	Ferredoxin
AOT14_22500	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AOT14_22520	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AOT14_22530	ENOG4108IAB	Phoh family
AOT14_22610	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AOT14_22640	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
AOT14_22660	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AOT14_22670	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
AOT14_22690	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AOT14_22700	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AOT14_22710	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AOT14_22720	ENOG4108Z4V	iron-sulfur cluster assembly
AOT14_22730	ENOG4105C5S	asparaginyl-tRNA synthetase
AOT14_22770	ENOG41077A9	carbonic anhydrase
AOT14_22790	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
AOT14_22800	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
AOT14_22810	ENOG4105CJB	Exodeoxyribonuclease I
AOT14_22900	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AOT14_22910	ENOG4105C7I	Dehydrogenase
AOT14_22930	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AOT14_22940	ENOG4105BZS	acriflavin resistance protein
AOT14_22980	ENOG4105F9F	transposase
AOT14_23000	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
AOT14_23010	ENOG4105C1G	acyl-Coa dehydrogenase
AOT14_23020	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AOT14_23030	ENOG4105C3R	Methionine synthase
AOT14_23040	ENOG4105C3R	Methionine synthase
AOT14_23060	ENOG4105EGI	Transcriptional regulator
AOT14_23070	ENOG4105CPN	adenine deaminase
AOT14_23080	ENOG4105D8G	Major Facilitator superfamily
AOT14_23110	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AOT14_23120	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AOT14_23150	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
AOT14_23160	ENOG4105CJ1	ABC, transporter
AOT14_23220	ENOG4107QTF	adenylosuccinate lyase
AOT14_23230	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT14_23250	ENOG4105BZU	Histidine kinase
AOT14_23260	ENOG4105EZE	Cupin 4 family protein
AOT14_23280	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AOT14_23290	ENOG4105C7S	Dehydrogenase
AOT14_23300	ENOG4107QN2	dihydrolipoyl dehydrogenase
AOT14_23310	ENOG4108URH	decarboxylase
AOT14_23320	ENOG4105BZU	Histidine kinase
AOT14_23330	ENOG4108MMM	RNA Polymerase
AOT14_23360	ENOG4105BZ1	(ABC) transporter
AOT14_23400	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AOT14_23410	ENOG4105CFG	Acts as a chaperone (By similarity)
AOT14_23420	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AOT14_23430	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AOT14_23440	ENOG41090R7	Ferric uptake
AOT14_23450	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AOT14_23480	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AOT14_23500	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AOT14_23530	ENOG4105E6M	Sulphatase-modifying factor protein
AOT14_23540	ENOG4108RVA	ribokinase
AOT14_23570	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
AOT14_23580	ENOG4107RJ1	sodium solute
AOT14_23590	ENOG4105CI0	Citrate lyase
AOT14_23670	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
AOT14_23680	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AOT14_23690	ENOG4105Y3E	Modulates RecA activity (By similarity)
AOT14_23700	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AOT14_23720	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AOT14_23730	ENOG4107TH8	cina domain protein
AOT14_23750	ENOG4105D7A	ATP-binding protein
AOT14_23760	ENOG4108RRZ	Transcription elongation factor GreB
AOT14_23780	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AOT14_23820	ENOG4105DHP	deoxycytidine triphosphate deaminase
AOT14_23840	ENOG4105D05	Receptor
AOT14_23850	ENOG4107RDJ	Sulfotransferase
AOT14_23870	ENOG4105C9K	Endothelin-converting enzyme 1
AOT14_23900	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AOT14_23910	ENOG4106UX7	integral membrane protein
AOT14_23940	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AOT14_23950	ENOG4105K4H	Nlp p60 protein
AOT14_23960	ENOG4105K4H	Nlp p60 protein
AOT14_23990	ENOG4105CK2	sodium dicarboxylate symporter
AOT14_24010	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AOT14_24020	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AOT14_24030	ENOG4105CTB	Polyprenyl synthetase
AOT14_24050	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AOT14_24060	ENOG4105N42	UPF0307 protein
AOT14_24080	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AOT14_24100	ENOG4105C03	ribonuclease
AOT14_24110	ENOG4108Z03	MAF-like protein
AOT14_24120	ENOG4105MPN	Membrane
AOT14_24160	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AOT14_24180	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AOT14_24210	ENOG4105C8T	Leucyl-tRNA synthetase
AOT14_24330	ENOG4105ED2	Beta-lactamase
AOT14_24340	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
AOT14_24350	ENOG4105CJ1	ABC, transporter
AOT14_24380	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AOT14_24400	ENOG4108R3D	Electron transport complex
AOT14_24420	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AOT14_24430	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AOT14_24460	ENOG4105KHC	sulfurtransferase
AOT14_24470	ENOG4105P8F	nudix hydrolase
AOT14_24480	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AOT14_24490	ENOG4105E39	Enoyl-CoA hydratase
AOT14_24510	ENOG4105CSM	endonuclease III
AOT14_24530	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
AOT14_24540	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
AOT14_24550	ENOG4105C8U	phosphate abc transporter
AOT14_24560	ENOG4105E2Z	phosphate ABC transporter (Permease
AOT14_24570	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AOT14_24580	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AOT14_24590	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AOT14_24600	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AOT14_24640	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AOT14_24650	ENOG4105CW7	secretion protein, HlyD family
AOT14_24680	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AOT14_24700	ENOG4105FQ6	thiopurine methyltransferase
AOT14_24710	ENOG4108UWD	Iron-storage protein
AOT14_24740	ENOG4105CAQ	asparagine synthetase
AOT14_24750	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AOT14_24760	ENOG4105KUZ	arsenate reductase
AOT14_24780	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AOT14_24790	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AOT14_24800	ENOG4105CE9	30S ribosomal protein S2
AOT14_24810	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AOT14_24820	ENOG4105BZU	Histidine kinase
AOT14_24830	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AOT14_24850	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AOT14_24860	ENOG4105KNE	Phosphatidate cytidylyltransferase
AOT14_24880	ENOG4105DZP	Membrane-associated zinc metalloprotease
AOT14_24890	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOT14_24900	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AOT14_24910	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AOT14_24920	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AOT14_24930	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AOT14_24940	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AOT14_24960	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AOT14_24970	ENOG4108YXA	Membrane
AOT14_25030	ENOG4108Q5Y	Membrane
AOT14_25100	ENOG4108Z7R	Chaperone CsaA
AOT14_25190	ENOG4105BZ1	(ABC) transporter
AOT14_25210	ENOG4105FQP	Beta-lactamase
AOT14_25250	ENOG4105BZU	Histidine kinase
AOT14_25260	ENOG4105FE9	pseudouridine synthase
AOT14_25270	ENOG4105BZU	Histidine kinase
AOT14_25300	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
AOT14_25380	ENOG4105UGU	tonB-dependent Receptor
AOT14_25430	ENOG4105MYN	Zinc uptake regulation protein
AOT14_25440	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AOT14_25460	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AOT14_25470	ENOG4105C29	acyl-CoA thioesterase
AOT14_25490	ENOG4105GFR	rna polymerase sigma factor
AOT14_25510	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
AOT14_25530	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AOT14_25580	ENOG4105F6J	Alpha beta hydrolase fold
AOT14_25640	ENOG4105WH1	Two component transcriptional regulator luxr family
AOT14_25650	ENOG4105BZU	Histidine kinase
AOT14_25670	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AOT14_25680	ENOG4107QMS	site-determining protein
AOT14_25690	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
AOT14_25710	ENOG4105EB3	Histidine kinase
AOT14_25730	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
AOT14_25750	ENOG4105DIJ	Phosphoethanolamine transferase
AOT14_25800	ENOG4105DTA	methyltransferase
AOT14_25860	ENOG4105C2C	drug resistance transporter, Bcr CflA
AOT14_25880	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AOT14_25910	ENOG4106AXJ	AraC family transcriptional regulator
AOT14_25940	ENOG41082F9	transcriptional regulator
AOT14_26060	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AOT14_26080	ENOG4105EPW	hflc protein
AOT14_26090	ENOG4107QJR	hflk protein
AOT14_26110	ENOG4105M3Z	response regulator
AOT14_26160	ENOG4108JQB	penicillin-binding protein 1C
AOT14_26170	ENOG4105DN3	alpha-2-macroglobulin domain protein
AOT14_26180	ENOG4105C7F	AcnD-accessory protein PrpF
AOT14_26190	ENOG4108I0Z	Aconitate hydratase
AOT14_26200	ENOG4105BZN	citrate synthase
AOT14_26220	ENOG4105CR4	methylisocitrate lyase
AOT14_26230	ENOG4105BZN	citrate synthase
AOT14_26270	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AOT14_26300	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AOT14_26310	ENOG4105D49	3-dehydroquinate synthase
AOT14_26340	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AOT14_26350	ENOG4105BZU	Histidine kinase
AOT14_26370	ENOG4105DS1	cytochrome b561
AOT14_26410	ENOG4105EJQ	L-serine dehydratase
AOT14_26420	ENOG4108KHX	Diguanylate cyclase
AOT14_26440	ENOG4105CFH	Aspartokinase
AOT14_26450	ENOG4105C28	cystathionine
AOT14_26460	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
AOT14_26480	ENOG4105DR5	peptidase
AOT14_26490	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AOT14_26500	ENOG4108UT2	hemolysin iii
AOT14_26510	ENOG41066T0	asmA family
AOT14_26540	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
AOT14_26550	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AOT14_26600	ENOG4107QPN	acyl-Coa dehydrogenase
AOT14_26670	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AOT14_26680	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AOT14_26700	ENOG4107QX8	SPFH domain, Band 7 family protein
AOT14_26720	ENOG4105KK4	UPF0060 membrane protein
AOT14_26730	ENOG4105DXN	mazG family
AOT14_26740	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
AOT14_26750	ENOG4107RK2	ADP-ribose diphosphatase NudE
AOT14_26760	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AOT14_26790	ENOG4105CBS	Chea signal transduction histidine kinase
AOT14_26800	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT14_26810	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
AOT14_26820	ENOG4105M3Z	response regulator
AOT14_26830	ENOG4108UNF	response regulator
AOT14_26840	ENOG4105D7Z	glutathione synthase
AOT14_26870	ENOG4107RNH	Outer membrane receptor FepA
AOT14_26900	ENOG4108Z9K	Osmotically inducible protein
AOT14_26950	ENOG4105KPV	Transcriptional regulator
AOT14_26980	ENOG4105C3K	feS assembly ATPase SufC
AOT14_26990	ENOG4105JRK	feS assembly protein SufD
AOT14_27000	ENOG4105C9B	Cysteine desulfurase
AOT14_27030	ENOG4108ESX	Receptor
AOT14_27050	ENOG4107E2E	PKHD-type hydroxylase
AOT14_27070	ENOG4105D05	Receptor
AOT14_27110	ENOG4105CJ2	(LipO)protein
AOT14_27120	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AOT14_27150	ENOG4106BE1	Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers (By similarity)
AOT14_27220	ENOG41080HT	Transcriptional regulator, arsr family
AOT14_27250	ENOG4105BZU	Histidine kinase
AOT14_27270	ENOG4105CY2	Citrate transporter
AOT14_27280	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
AOT14_27310	ENOG4105EHM	Aminoglycoside phosphotransferase
AOT14_27320	ENOG4108S0S	Nucleotidyl transferase
AOT14_27330	ENOG4105C02	permease
AOT14_27350	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AOT14_27380	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AOT14_27410	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AOT14_27420	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AOT14_27430	ENOG4107TUY	Histidine kinase
AOT14_27440	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AOT14_27470	ENOG4107QHF	type ii secretion system protein e
AOT14_27480	ENOG4105CMR	udp-glucose 4-epimerase
AOT14_27510	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AOT14_27520	ENOG4107SK7	Sarcosine-dimethylglycine methyltransferase
AOT14_27530	ENOG4105D9R	oxidoreductase
AOT14_27560	ENOG4105CVN	desaturase
AOT14_27600	ENOG4105D7Q	type ii secretion system
AOT14_27610	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
AOT14_27620	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AOT14_27630	ENOG4105BZU	Histidine kinase
AOT14_27640	ENOG4105ETX	regulatoR
AOT14_27660	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AOT14_27700	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AOT14_27710	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AOT14_27760	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AOT14_27780	ENOG4105C4K	Nad synthetase
AOT14_27790	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AOT14_27800	ENOG4105BZG	amino acid carrier protein
AOT14_27820	ENOG4105BZS	acriflavin resistance protein
AOT14_27830	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AOT14_27840	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
AOT14_27850	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AOT14_27860	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AOT14_27870	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AOT14_27880	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AOT14_27920	ENOG4107R11	Transcriptional regulator
AOT14_27950	ENOG4108UVJ	appr-1-p processing domain protein
AOT14_27960	ENOG4107R1Y	fructose-bisphosphate aldolase
AOT14_27970	ENOG4105CA9	Pyruvate kinase
AOT14_27990	ENOG4105BZA	Phosphoglycerate kinase
AOT14_28000	ENOG4105D9U	N-acetyltransferase
AOT14_28030	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AOT14_28040	ENOG4105EIF	outer membrane protein W
AOT14_28090	ENOG4105CYC	Transferase
AOT14_28130	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AOT14_28140	ENOG4105CK2	sodium dicarboxylate symporter
AOT14_28200	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AOT14_28210	ENOG4105E4G	Type IV pilus
AOT14_28260	ENOG4108JQC	penicillin-binding protein 1A
AOT14_28280	ENOG4105BZN	citrate synthase
AOT14_28290	ENOG4105NRA	50s ribosomal protein l31 type b
AOT14_28300	ENOG4105DU0	nucleoside hydrolase
AOT14_28310	ENOG4105CB5	ATP-dependent DNA helicase recG
AOT14_28320	ENOG4105KME	endoribonuclease L-psp
AOT14_28330	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AOT14_28340	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AOT14_28350	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AOT14_28370	ENOG4105DSJ	YicC domain protein
AOT14_28380	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AOT14_28390	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
AOT14_28400	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AOT14_28410	ENOG4105CSA	Coproporphyrinogen iii oxidase
AOT14_28440	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
AOT14_28460	ENOG4107RAQ	aminopeptidase
AOT14_28490	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
AOT14_28510	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AOT14_28530	ENOG4105E66	phosphoriboisomerase A
AOT14_28580	ENOG41063JG	Transcriptional regulator
AOT14_28590	ENOG4105VCQ	rubredoxin
AOT14_28600	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AOT14_28620	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AOT14_28640	ENOG4105K59	histidine triad (HIT) protein
AOT14_28650	ENOG4105C8Y	Acetylornithine aminotransferase
AOT14_28660	ENOG4105EYW	Ion transport protein
AOT14_28700	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AOT14_28720	ENOG4105DFU	Cell wall formation (By similarity)
AOT14_28740	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AOT14_28790	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AOT14_28800	ENOG4105F0N	pyrophosphate phospho-hydrolase
AOT14_28850	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AOT14_28870	ENOG4105C94	Transporter
AOT14_28880	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AOT14_28990	ENOG4105D7Q	type ii secretion system
AOT14_29050	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AOT14_29080	ENOG4105C7B	Threonine dehydratase
AOT14_29090	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AOT14_29120	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AOT14_29130	ENOG4105D82	Glutamate dehydrogenase
AOT14_29180	ENOG4105D82	Glutamate dehydrogenase
AOT14_29250	ENOG4105C5Q	Transcriptional regulator
AOT14_29260	ENOG4105NXH	GreA GreB family elongation factor
AOT14_29270	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AOT14_29320	ENOG4105CX6	glutaminyL-tRNA synthetase
AOT14_29340	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
AOT14_29380	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AOT14_29390	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AOT14_29400	ENOG4105D0A	hydroxylase
AOT14_29410	ENOG4108WBT	adenosyltransferase
AOT14_29420	ENOG4105DGU	Histone deacetylase
AOT14_29430	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AOT14_29440	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AOT14_29450	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AOT14_29460	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AOT14_29470	ENOG4105NWN	ApaG protein
AOT14_29480	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AOT14_29510	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AOT14_29520	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AOT14_29560	ENOG4105EE5	Membrane protein terC
AOT14_29570	ENOG41080IJ	Diacylglycerol kinase
AOT14_29580	ENOG4105DHQ	Histidine kinase
AOT14_29590	ENOG4105ETX	regulatoR
AOT14_29620	ENOG4107ENK	receptor
AOT14_29640	ENOG4105CPC	Aldo Keto reductase
AOT14_29650	ENOG4105D9N	nucleoside
AOT14_29670	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AOT14_29720	ENOG4107KET	secretion protein, HlyD family
AOT14_29760	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AOT14_29780	ENOG4105D9P	serine threonine protein kinase
AOT14_29790	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AOT14_29810	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AOT14_29830	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
AOT14_29860	ENOG4105SYT	Methylenetetrahydrofolate reductase
AOT14_29880	ENOG4105M6F	mutator MutT protein
AOT14_29890	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AOT14_29900	ENOG4105DR5	peptidase
AOT14_29920	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AOT14_29940	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AOT14_29950	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AOT14_29960	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
AOT14_29970	ENOG4105DFU	Cell wall formation (By similarity)
AOT14_29980	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AOT14_30000	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AOT14_30010	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
AOT14_30020	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AOT14_30030	ENOG4105CJN	penicillin-binding protein
AOT14_30040	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AOT14_30050	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AOT14_30060	ENOG4108V6E	Cell division protein mraZ
AOT14_30110	ENOG41082RQ	UPF0102 protein
AOT14_30120	ENOG4105S2T	inner membrane protein YbcI
AOT14_30130	ENOG4105CQB	FAD linked oxidase domain protein
AOT14_30140	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AOT14_30150	ENOG4107YIM	Involved in the transcription termination process (By similarity)
AOT14_30160	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AOT14_30170	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AOT14_30190	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AOT14_30210	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AOT14_30220	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AOT14_30240	ENOG4105C5H	ABC transporter
AOT14_30250	ENOG4105C7N	Xanthine uracil vitamin C permease
AOT14_30270	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
AOT14_30280	ENOG4105EJG	cellulose synthase
AOT14_30290	ENOG4107EEX	Cellulose synthase regulator protein
AOT14_30300	ENOG4107QZ7	Cellulose synthase catalytic subunit
AOT14_30330	ENOG4105D1V	cellulose synthase operon protein YhjU
AOT14_30350	ENOG4105U74	cellulose biosynthesis protein BcsE
AOT14_30360	ENOG4107RH7	Nicotinate phosphoribosyltransferase
AOT14_30370	ENOG4105EJG	cellulose synthase
AOT14_30380	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
AOT14_30390	ENOG4107EEX	Cellulose synthase regulator protein
AOT14_30400	ENOG4107QZ7	Cellulose synthase catalytic subunit
AOT14_30450	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AOT14_30470	ENOG4105T95	Thiol disulfide interChange protein
AOT14_30480	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AOT14_30500	ENOG4108K5H	permease YjgP YjgQ family protein
AOT14_30520	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AOT14_30570	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
AOT14_30590	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AOT14_30610	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AOT14_30620	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
AOT14_30650	ENOG4105DHJ	ABC, transporter
AOT14_30660	ENOG4108SNX	Mammalian cell entry related domain protein
AOT14_30690	ENOG4106A4F	Removes the N-terminal methionine from nascent proteins (By similarity)
AOT14_30710	ENOG4107S1E	Beta-lactamase
AOT14_30720	ENOG4105T0Z	Conserved Protein
AOT14_30780	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AOT14_30860	ENOG4105EUP	HipA domain protein
AOT14_30880	ENOG4105F2I	Transposase
AOT14_30960	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AOT14_30980	ENOG4105Q26	Siderophore-interacting protein
AOT14_31020	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
AOT14_31070	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AOT14_31110	ENOG4105KWI	UPF0339 protein
AOT14_31120	ENOG41082IR	Excinuclease ABC C subunit domain protein
AOT14_31140	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AOT14_31160	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AOT14_31170	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AOT14_31180	ENOG4105VF7	tolerance protein
AOT14_31200	ENOG4107QX9	Thiol disulfide interChange protein
AOT14_31210	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AOT14_31220	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AOT14_31230	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AOT14_31240	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AOT14_31260	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
AOT14_31270	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AOT14_31300	ENOG4105C12	Phosphoribosylglycinamide synthetase
AOT14_31310	ENOG4105CPC	Aldo Keto reductase
AOT14_31320	ENOG4105EQ2	LysR family Transcriptional regulator
AOT14_31330	ENOG4105EM2	membrane
AOT14_31360	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
AOT14_31400	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AOT14_31420	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AOT14_31470	ENOG4105BZU	Histidine kinase
AOT14_31480	ENOG4108UQY	Iron-storage protein
AOT14_31500	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AOT14_31540	ENOG4108UJD	30S ribosomal protein S9
AOT14_31550	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AOT14_31560	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
AOT14_31580	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
AOT14_31590	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
AOT14_31600	ENOG410635A	Membrane
AOT14_31620	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AOT14_31630	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AOT14_31650	ENOG4105DDQ	anthranilate synthase
AOT14_31660	ENOG4105F2I	Transposase
AOT14_31690	ENOG4107QJE	Chromosome Partitioning Protein
AOT14_31760	ENOG4107YH6	single-stranded DNA-binding protein
AOT14_31770	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AOT14_32190	ENOG4105W5Q	DNA repair protein (RadC
AOT14_32350	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AOT14_32360	ENOG4105D0S	secretion protein (HlyD
AOT14_32370	ENOG4105CJ1	ABC, transporter
AOT14_32380	ENOG4105CMI	transporter
AOT14_32400	ENOG4105CHR	reductase
AOT14_32430	ENOG4105CHR	reductase
AOT14_32440	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AOT14_32450	ENOG4105D6U	Sodium Glutamate Symporter
AOT14_32460	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
AOT14_32470	ENOG41081QV	Universal stress protein
AOT14_32490	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AOT14_32510	ENOG4105CY0	Metallo-Beta-Lactamase
AOT14_32520	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
AOT14_32530	ENOG4106NZI	LysR family Transcriptional regulator
AOT14_32550	ENOG4105DFP	Integrase
AOT14_32570	ENOG4105CRQ	synthase (Component I)
AOT14_32630	ENOG4105DJV	ribulose-phosphate 3-epimerase
AOT14_32640	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
AOT14_32650	ENOG4105C8V	SAICAR synthetase
AOT14_32680	ENOG4105D65	subunit l
AOT14_32690	ENOG4108ZE9	Monovalent cation H antiporter subunit C
AOT14_32700	ENOG4107R4Z	monovalent cation h antiporter subunit d
AOT14_32720	ENOG4105W4C	monovalent cation H antiporter subunit F
AOT14_32730	ENOG4105KJM	monovalent cation h antiporter subunit g
AOT14_32750	ENOG4105F1J	Homogentisate 1,2-dioxygenase
AOT14_32760	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
AOT14_32800	ENOG4105DUX	Transporter
AOT14_32810	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
AOT14_32820	ENOG4107RUY	(E1 component), alpha subunit
AOT14_32830	ENOG4105CPP	Dehydrogenase, E1 component
AOT14_32850	ENOG4105C7S	Dehydrogenase
AOT14_32900	ENOG4105K4T	epimerase
AOT14_32910	ENOG4105BZU	Histidine kinase
AOT14_32930	ENOG4108JJA	ABC, transporter
AOT14_32950	ENOG4105CKW	Inner membrane protein yedI
AOT14_32960	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AOT14_32970	ENOG4107RES	phosphoglycerol transferase I
AOT14_32980	ENOG4105EGS	Mechanosensitive ion channel
AOT14_33010	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AOT14_33040	ENOG4108W15	Protein of unknown function (DUF1456)
AOT14_33170	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
AOT14_33230	ENOG4105C0H	protease
AOT14_33270	ENOG4105DSF	transport protein
AOT14_33290	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AOT14_33300	ENOG4107VGR	Catalase
AOT14_33320	ENOG4108S01	response regulator
AOT14_33330	ENOG4105BZU	Histidine kinase
AOT14_33340	ENOG4105KCT	ABC transporter
AOT14_33350	ENOG4108M15	ABC transporter
AOT14_33360	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AOT14_33370	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AOT14_33390	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AOT14_33420	ENOG4105FR1	rard protein
AOT14_33430	ENOG4105FDR	Membrane
AOT14_33470	ENOG4105C31	Tryptophanyl-tRNA synthetase
AOT14_33490	ENOG4105VDW	Csbd family
AOT14_33520	ENOG41066UZ	arginase EC 3.5.3.1
AOT14_33530	ENOG4105D4P	Coproporphyrinogen iii oxidase
AOT14_33540	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
AOT14_33560	ENOG4105DSQ	Nitric oxide reductase
AOT14_33640	ENOG4105CPW	cytochrome b561
AOT14_33680	ENOG4108ESX	Receptor
AOT14_33710	ENOG4105VMP	Transcriptional regulator
AOT14_33730	ENOG4105BZU	Histidine kinase
AOT14_33750	ENOG4105BZU	Histidine kinase
AOT14_33760	ENOG41068CG	regulatoR
AOT14_33770	ENOG4106AS2	Outer membrane autotransporter
AOT14_33800	ENOG4105ED4	portal protein
AOT14_34300	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
AOT14_34310	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AOT14_34340	ENOG4105EB3	Histidine kinase
AOT14_34350	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AOT14_34370	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AOT14_34380	ENOG4105CNA	YD repeat protein
AOT14_34400	ENOG410814C	multidrug resistance protein
AOT14_34500	ENOG4105KT7	mgtC SapB transporter
AOT14_34510	ENOG4108RWI	nicotinamidase
AOT14_34530	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AOT14_34540	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AOT14_34560	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AOT14_34570	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AOT14_34620	ENOG4105D6Z	AFG1 family ATPase
AOT14_34640	ENOG4108TZV	Membrane
AOT14_34690	ENOG4105C1G	acyl-Coa dehydrogenase
AOT14_34700	ENOG4107QX3	carboxylase
AOT14_34750	ENOG4105BZU	Histidine kinase
AOT14_34760	ENOG4108I9X	Isocitrate lyase
AOT14_34770	ENOG4107QP3	malate synthase g
AOT14_34780	ENOG4107R11	Transcriptional regulator
AOT14_34800	ENOG4105CXG	d-lactate dehydrogenase
AOT14_34810	ENOG4105DMF	Dehydrogenase
AOT14_34820	ENOG41073TP	transcriptional regulator
AOT14_34830	ENOG4105DAA	L-lactate
AOT14_34840	ENOG4105DY9	regulatoR
AOT14_34870	ENOG4105C3F	Signal peptidase i
AOT14_34900	ENOG4105DGW	oligopeptidase A
AOT14_34910	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AOT14_34930	ENOG4108YZN	class I peptide chain release factor
AOT14_34970	ENOG4107QJZ	Glycosyl transferase, family 2
AOT14_34990	ENOG4105F2I	Transposase
AOT14_35020	ENOG4105DR9	pseudouridine synthase
AOT14_35040	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AOT14_35060	ENOG4105CPF	Cell wall formation (By similarity)
AOT14_35090	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
AOT14_35100	ENOG410680H	amp-dependent synthetase and ligase
AOT14_35120	ENOG4108J2P	Alpha beta hydrolase fold
AOT14_35130	ENOG4108RG0	uracil-dna glycosylase
AOT14_35140	ENOG4106RHG	Yeca family
AOT14_35150	ENOG4105E2T	synthase III
AOT14_35190	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AOT14_35210	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AOT14_35220	ENOG4105C1G	acyl-Coa dehydrogenase
AOT14_35230	ENOG4105C85	amino acid
AOT14_35250	ENOG4105DVT	helicase
AOT14_35270	ENOG4105E2X	shikimate dehydrogenase
AOT14_35300	ENOG4105D52	delta-aminolevulinic acid dehydratase
AOT14_35310	ENOG4105FFC	UPF0187 protein
AOT14_35390	ENOG4105F2I	Transposase
AOT14_35420	ENOG4105CYM	Glutathione S-transferase
AOT14_35450	ENOG4108SDH	ABC, transporter
AOT14_35460	ENOG4108IUW	ABC transporter
AOT14_35510	ENOG4105BZU	Histidine kinase
AOT14_35530	ENOG4105DA5	(ABC) transporter
AOT14_35540	ENOG4105E3A	(ABC) transporter
AOT14_35550	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AOT14_35580	ENOG4105F8V	Hydrolase, tatD family
AOT14_35590	ENOG4105CQ7	ATP-dependent helicase
AOT14_35610	ENOG4108R99	pseudouridine synthase
AOT14_35650	ENOG4105CD5	CoA-binding domain protein
AOT14_35670	ENOG4105CJW	magnesium transporter
AOT14_35680	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AOT14_35710	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AOT14_35730	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
AOT14_35740	ENOG4105C2D	reductase
AOT14_35750	ENOG4105M2Z	protein tyrosine serine phosphatase
AOT14_35760	ENOG4107ZSV	Receptor
AOT14_35820	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AOT14_35900	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AOT14_35910	ENOG4107VMU	Membrane
AOT14_35930	ENOG4105C2M	dna polymerase I
AOT14_35960	ENOG4105C4R	Atp-dependent dna helicase
AOT14_35980	ENOG4105W0E	50S ribosomal protein L33
AOT14_35990	ENOG4105KDC	50s ribosomal protein l28
AOT14_36080	ENOG4105D05	Receptor
AOT14_36090	ENOG4105CTK	cobaltochelatase, cobn subunit
AOT14_36130	ENOG4105CKK	Glycosyl transferase, family 2
AOT14_36160	ENOG4105FA0	parb-like partition protein
AOT14_36170	ENOG4107QJE	Chromosome Partitioning Protein
AOT14_36180	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AOT14_36220	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
AOT14_36240	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AOT14_36260	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AOT14_36270	ENOG41076YT	nitrate reductase, gamma subunit
AOT14_36280	ENOG4105R3A	Nitrate reductase
AOT14_36290	ENOG4108IUE	nitrate reductase beta subunit
AOT14_36300	ENOG4105CRU	nitrate reductase, alpha subunit
AOT14_36310	ENOG4105DQQ	Major facilitator superfamily MFS_1
AOT14_36330	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AOT14_36340	ENOG4108ZAF	Molybdopterin
AOT14_36360	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AOT14_36370	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AOT14_36380	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AOT14_36410	ENOG4105F4R	Transcriptional regulator mode
AOT14_36420	ENOG4105D05	Receptor
AOT14_36440	ENOG4105S10	periplasmic binding protein
AOT14_36450	ENOG4108I9K	permease protein
AOT14_36460	ENOG4105E0A	ABC, transporter
AOT14_36470	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
AOT14_36490	ENOG41062QD	Membrane
AOT14_36510	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AOT14_36530	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT14_36540	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
AOT14_36550	ENOG4105BZU	Histidine kinase
AOT14_36570	ENOG4105BZU	Histidine kinase
AOT14_36610	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AOT14_36620	ENOG4108PYU	two-component system response regulator
AOT14_36660	ENOG4105CFU	surface antigen
AOT14_36690	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AOT14_36700	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
AOT14_36710	ENOG4107QHF	type ii secretion system protein e
AOT14_36720	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AOT14_36740	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AOT14_36750	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AOT14_36780	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AOT14_36790	ENOG4105D74	hydrolase
AOT14_36810	ENOG4105DH7	May be involved in recombination (By similarity)
AOT14_36820	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AOT14_36870	ENOG4105E55	glycerol-3-phosphate acyltransferase
AOT14_36890	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AOT14_36900	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
AOT14_36910	ENOG4108YXG	UPF0502 protein
AOT14_36920	ENOG41068WN	
AOT14_36930	ENOG4105C4R	Atp-dependent dna helicase
AOT14_36940	ENOG4107104	thymidine kinase
AOT14_36960	ENOG4105DJ9	glucan biosynthesis protein
AOT14_36970	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AOT14_37030	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT14_37060	ENOG4105D78	K07001 NTE family protein
AOT14_37100	ENOG4105CTK	cobaltochelatase, cobn subunit
AOT14_37110	ENOG4105D05	Receptor
AOT14_37130	ENOG4105MIR	Phenylalanine 4-monooxygenase
AOT14_37160	ENOG4105WH1	Two component transcriptional regulator luxr family
AOT14_37260	ENOG4105C2I	pirin domain protein
AOT14_37270	ENOG4105HEI	LysR family (Transcriptional regulator
AOT14_37290	ENOG4105C7H	Helicase, RecD TraA family
AOT14_37300	ENOG4107QKA	exodeoxyribonuclease V beta
AOT14_37310	ENOG4105DSY	exodeoxyribonuclease V, gamma
AOT14_37320	ENOG4105DHJ	ABC, transporter
AOT14_37330	ENOG4105CY3	ABC transporter, permease
AOT14_37340	ENOG4107PE3	Mammalian cell entry related domain protein
AOT14_37370	ENOG410903C	(LipO)protein
AOT14_37390	ENOG4108V06	Glutathione peroxidase
AOT14_37410	ENOG4105CGY	Dna recombination protein
AOT14_37420	ENOG4108NIW	Leucine export protein LeuE
AOT14_37440	ENOG4105CUB	amino acid
AOT14_37460	ENOG4105DR4	Methyltransferase
AOT14_37480	ENOG4105DU1	integral membrane protein, terc
AOT14_37500	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
AOT14_37540	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AOT14_37550	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AOT14_37560	ENOG4105VG0	50S ribosomal protein l34