locus-tag	class	description
CEP89_00040	ENOG4108IUW	ABC transporter
CEP89_00055	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CEP89_00060	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CEP89_00065	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
CEP89_00070	ENOG4107S2Z	UPF0761 membrane protein
CEP89_00075	ENOG4107QSV	RmuC domain protein
CEP89_00080	ENOG4108IUJ	4-alpha-glucanotransferase
CEP89_00085	ENOG4105D1H	recombination factor protein RarA
CEP89_00105	ENOG4105K63	Thioredoxin
CEP89_00155	ENOG4105C26	Dehydrogenase
CEP89_00160	ENOG4105DKQ	ROK family
CEP89_00170	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CEP89_00185	ENOG4105CP7	Triose-phosphate isomerase
CEP89_00215	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CEP89_00225	ENOG4105CGK	Exodeoxyribonuclease III
CEP89_00230	ENOG4105TMB	Formate nitrite transporter
CEP89_00235	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CEP89_00260	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CEP89_00265	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CEP89_00270	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CEP89_00280	ENOG4105CDY	transcriptional regulatory protein
CEP89_00285	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
CEP89_00290	ENOG4105CHV	Transcription elongation factor NusA
CEP89_00300	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CEP89_00305	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CEP89_00310	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CEP89_00315	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CEP89_00320	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CEP89_00325	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CEP89_00330	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CEP89_00335	ENOG4105DTN	riboflavin biosynthesis protein ribF
CEP89_00340	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
CEP89_00345	ENOG4105CJR	Integral membrane protein (MviN
CEP89_00355	ENOG4108Z03	MAF-like protein
CEP89_00375	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CEP89_00385	ENOG4105EN6	Membrane
CEP89_00395	ENOG4108YS0	lipoprotein YafL
CEP89_00400	ENOG4107104	thymidine kinase
CEP89_00430	ENOG4105E2X	shikimate dehydrogenase
CEP89_00440	ENOG4107QMP	dna polymerase iii subunits gamma and tau
CEP89_00445	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CEP89_00450	ENOG4105CDU	Replicative dna helicase
CEP89_00455	ENOG4105CFP	Peptidase U32
CEP89_00460	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CEP89_00465	ENOG4105GR3	Histidine kinase
CEP89_00480	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
CEP89_00490	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CEP89_00495	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
CEP89_00505	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
CEP89_00525	ENOG4105CJW	magnesium transporter
CEP89_00535	ENOG4105C5H	ABC transporter
CEP89_00565	ENOG41066VF	YeeE YedE family protein
CEP89_00570	ENOG4105GRF	N-glycosylase DNA lyase
CEP89_00580	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CEP89_00590	ENOG4108WF2	Metal Dependent Phosphohydrolase
CEP89_00595	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CEP89_00600	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CEP89_00605	ENOG4108JU3	Alkyl hydroperoxide reductase
CEP89_00610	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CEP89_00615	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
CEP89_00625	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
CEP89_00630	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
CEP89_00635	ENOG4105CN1	protease
CEP89_00640	ENOG4105DX0	Hemolysin A
CEP89_00655	ENOG4105CFP	Peptidase U32
CEP89_00670	ENOG4107RBB	ABC transporter, permease
CEP89_00675	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CEP89_00695	ENOG4105CI3	gtp-binding protein typa
CEP89_00760	ENOG4108JJB	ABC transporter
CEP89_00775	ENOG4105BZ1	(ABC) transporter
CEP89_00780	ENOG4105BZ1	(ABC) transporter
CEP89_00790	ENOG4105CEE	C4-dicarboxylate transporter
CEP89_00810	ENOG4105ETE	Transcriptional regulator (LacI family
CEP89_00835	ENOG4105EKQ	RNA-directed DNA polymerase
CEP89_00845	ENOG4105CQR	helicase
CEP89_00945	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CEP89_00950	ENOG4105CHM	Aminotransferase
CEP89_00965	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CEP89_00970	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CEP89_00975	ENOG4107QRG	dna polymerase iii
CEP89_00980	ENOG4105DFF	Rod shape-determining protein mreb
CEP89_00985	ENOG4105C8N	cysteinyl-tRNA synthetase
CEP89_00990	ENOG4105C98	muts2 protein
CEP89_01000	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CEP89_01005	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CEP89_01010	ENOG4105JFG	SpoIID LytB domain protein
CEP89_01020	ENOG4108REF	Sporulation integral membrane protein ytvi
CEP89_01025	ENOG4105D01	(LipO)protein
CEP89_01030	ENOG4108UMI	ABC transporter, permease
CEP89_01035	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CEP89_01045	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CEP89_01055	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
CEP89_01060	ENOG4105CTB	Polyprenyl synthetase
CEP89_01070	ENOG4106H78	methyltransferase
CEP89_01075	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CEP89_01080	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CEP89_01085	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CEP89_01090	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CEP89_01095	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
CEP89_01100	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CEP89_01150	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
CEP89_01165	ENOG4105EUR	Domain-Containing protein
CEP89_01175	ENOG4105E5Q	amino acid AbC transporter
CEP89_01180	ENOG4108JQC	penicillin-binding protein 1A
CEP89_01185	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CEP89_01190	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
CEP89_01205	ENOG4105KNE	Phosphatidate cytidylyltransferase
CEP89_01210	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CEP89_01215	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
CEP89_01220	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
CEP89_01230	ENOG4105DXX	methyltransferase
CEP89_01235	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CEP89_01275	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CEP89_01280	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CEP89_01285	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
CEP89_01290	ENOG4108HQR	Glycine betaine
CEP89_01295	ENOG4108IJ8	ABC transporter
CEP89_01310	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CEP89_01325	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
CEP89_01330	ENOG4105F8V	Hydrolase, tatD family
CEP89_01375	ENOG4108RWN	rrna methyltransferase
CEP89_01380	ENOG4105K59	histidine triad (HIT) protein
CEP89_01385	ENOG4108YZG	isomerase
CEP89_01400	ENOG4105DD7	kinase (PfkB family
CEP89_01415	ENOG4108IA2	Sodium pantothenate symporter
CEP89_01430	ENOG4105CHM	Aminotransferase
CEP89_01465	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CEP89_01470	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CEP89_01475	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
CEP89_01480	ENOG4106W3N	
CEP89_01485	ENOG4105CGH	5'-nucleotidase
CEP89_01510	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CEP89_01515	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
CEP89_01520	ENOG4107YR5	Diacylglycerol kinase
CEP89_01525	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CEP89_01530	ENOG4105CTJ	Metal Dependent Phosphohydrolase
CEP89_01535	ENOG4105DVT	helicase
CEP89_01540	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
CEP89_01545	ENOG4105NRA	50s ribosomal protein l31 type b
CEP89_01550	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CEP89_01565	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CEP89_01570	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CEP89_01575	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
CEP89_01590	ENOG41083ND	50S ribosomal protein L33
CEP89_01595	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
CEP89_01600	ENOG4105CIN	aminoacyl-histidine dipeptidase
CEP89_01605	ENOG4105VB6	UPF0109 protein
CEP89_01615	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CEP89_01620	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CEP89_01625	ENOG4105KG3	cytidine deaminase
CEP89_01630	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
CEP89_01635	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
CEP89_01640	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
CEP89_01645	ENOG4105DIH	basic membrane
CEP89_01655	ENOG4105UIB	(ABC) transporter
CEP89_01660	ENOG4108JQ9	ABC transporter
CEP89_01665	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CEP89_01685	ENOG4105K46	50S ribosomal protein l27
CEP89_01695	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CEP89_01700	ENOG4105D6U	Sodium Glutamate Symporter
CEP89_01705	ENOG4105ENA	helicase
CEP89_01715	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CEP89_01720	ENOG410849Z	50s ribosomal protein L35
CEP89_01725	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CEP89_01740	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CEP89_01745	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CEP89_01750	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CEP89_01755	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CEP89_01760	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CEP89_01765	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CEP89_01770	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CEP89_01775	ENOG4107XK9	50S ribosomal protein L10
CEP89_01810	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
CEP89_01815	ENOG4105DUM	transcriptional regulator, lysR family
CEP89_01820	ENOG4105C7N	Xanthine uracil vitamin C permease
CEP89_01825	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
CEP89_01840	ENOG4106N3A	copper homeostasis protein cutc
CEP89_01865	ENOG4108IV0	ABC, transporter
CEP89_01870	ENOG4105C0Z	ABC transporter
CEP89_01875	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
CEP89_01880	ENOG4105C32	Amino acid ABC transporter (Permease)
CEP89_01960	ENOG4105CN1	protease
CEP89_01965	ENOG4107VMB	Beta-lactamase domain protein
CEP89_01975	ENOG4107QN2	dihydrolipoyl dehydrogenase
CEP89_01980	ENOG4105C3G	gtp-binding protein
CEP89_01990	ENOG4105Q2H	domain protein
CEP89_02000	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CEP89_02005	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CEP89_02020	ENOG4105C5S	asparaginyl-tRNA synthetase
CEP89_02050	ENOG4108IJ9	(ABC) transporter
CEP89_02055	ENOG4105EG2	ABC transporter, permease
CEP89_02060	ENOG4105D56	permease protein
CEP89_02075	ENOG4105CJ1	ABC, transporter
CEP89_02095	ENOG4108IUM	Glycogen debranching enzyme
CEP89_02100	ENOG4108IUJ	4-alpha-glucanotransferase
CEP89_02105	ENOG4105FKQ	transcriptional regulator
CEP89_02110	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CEP89_02115	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CEP89_02120	ENOG4107QSI	ABC, transporter
CEP89_02125	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CEP89_02130	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CEP89_02135	ENOG4105CA9	Pyruvate kinase
CEP89_02140	ENOG4105CTQ	phosphohexokinase
CEP89_02165	ENOG4105C5Y	PTS System
CEP89_02175	ENOG4105C31	Tryptophanyl-tRNA synthetase
CEP89_02180	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CEP89_02185	ENOG4105DZ1	carboxypeptidase
CEP89_02205	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
CEP89_02210	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CEP89_02215	ENOG4105DFS	Conserved Protein
CEP89_02235	ENOG4108159	Pfam:UPF0005
CEP89_02240	ENOG4105C22	threonyL-tRNA synthetase
CEP89_02265	ENOG4105D38	putrescine abc transporter
CEP89_02270	ENOG4105F38	ABC transporter, permease
CEP89_02275	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CEP89_02280	ENOG4105DFM	M18 family aminopeptidase
CEP89_02285	ENOG4105CTD	carboxy-peptidase
CEP89_02315	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CEP89_02320	ENOG4105C37	(CBS) domain
CEP89_02330	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
CEP89_02335	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CEP89_02345	ENOG4105C25	Primosomal protein n'
CEP89_02350	ENOG4105CJN	penicillin-binding protein
CEP89_02355	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CEP89_02360	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CEP89_02365	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CEP89_02380	ENOG4105DVE	abc transporter atp-binding protein
CEP89_02395	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CEP89_02410	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CEP89_02415	ENOG4105CBG	Sulfatase
CEP89_02420	ENOG4105CK7	Sodium proline symporter
CEP89_02425	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CEP89_02430	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CEP89_02435	ENOG4107RZZ	dna polymerase iii epsilon subunit
CEP89_02440	ENOG4105BZ1	(ABC) transporter
CEP89_02450	ENOG4105C8T	Leucyl-tRNA synthetase
CEP89_02455	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CEP89_02460	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
CEP89_02485	ENOG4108ZT0	50S ribosomal protein l17
CEP89_02490	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CEP89_02495	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CEP89_02500	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CEP89_02505	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CEP89_02515	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CEP89_02525	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CEP89_02530	ENOG4105C75	arginyL-tRNA synthetase
CEP89_02535	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
CEP89_02545	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CEP89_02550	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CEP89_02570	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CEP89_02575	ENOG4107R6U	sodium dicarboxylate symporter
CEP89_02580	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
CEP89_02590	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
CEP89_02595	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
CEP89_02600	ENOG4108HWV	)-transporter
CEP89_02605	ENOG4105C2J	ABC transporter
CEP89_02610	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
CEP89_02615	ENOG4105E2R	ROK family
CEP89_02620	ENOG4105DBI	uridine monophosphokinase
CEP89_02625	ENOG4105DM4	PTS System
CEP89_02630	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CEP89_02635	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CEP89_02640	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
CEP89_02660	ENOG4105CC5	ABC transporter
CEP89_02665	ENOG4105FDK	ABC transporter
CEP89_02675	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
CEP89_02735	ENOG4105F1A	Pyruvate formate-lyase
CEP89_02745	ENOG4105C3J	Cysteine desulfurase
CEP89_02750	ENOG4107RFW	hydrolase family 57
CEP89_02760	ENOG4105C3F	Signal peptidase i
CEP89_02765	ENOG4105CBT	Fructose-1,6-bisphosphatase
CEP89_02770	ENOG4105VB9	50S ribosomal protein l28
CEP89_02785	ENOG4105CKT	filamentous hemagglutinin
CEP89_02790	ENOG4105D01	(LipO)protein
CEP89_02795	ENOG4108UMI	ABC transporter, permease
CEP89_02800	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CEP89_02805	ENOG4105C4Y	ABC transporter
CEP89_02810	ENOG4107RCV	ABC transporter, permease
CEP89_02815	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CEP89_02840	ENOG4108V0P	LemA family
CEP89_02845	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CEP89_02850	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CEP89_02865	ENOG4105MA4	psp1 domain protein
CEP89_02870	ENOG4108XS9	dna repair protein
CEP89_02875	ENOG4105CKU	formyltetrahydrofolate synthetase
CEP89_02905	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CEP89_02920	ENOG4108IJ9	(ABC) transporter
CEP89_02925	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CEP89_02930	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
CEP89_02935	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
CEP89_02940	ENOG4105KXQ	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CEP89_02950	ENOG41083MH	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CEP89_02970	ENOG4105E0X	reductase
CEP89_03010	ENOG4105D7Q	type ii secretion system
CEP89_03055	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
CEP89_03065	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CEP89_03075	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CEP89_03110	ENOG4105CAH	Chromate
CEP89_03120	ENOG4105C5I	Dehydrogenase
CEP89_03145	ENOG4105CC5	ABC transporter
CEP89_03150	ENOG4107RPQ	ABC transporter
CEP89_03155	ENOG4105DIK	(ABC) transporter
CEP89_03160	ENOG4107SIG	periplasmic solute binding protein
CEP89_03185	ENOG4105DFF	Rod shape-determining protein mreb
CEP89_03190	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CEP89_03195	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CEP89_03200	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CEP89_03205	ENOG4105CE9	30S ribosomal protein S2
CEP89_03215	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CEP89_03235	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CEP89_03240	ENOG4105C7J	ABC transporter, permease
CEP89_03260	ENOG4105CS2	ec 3.2.1.21
CEP89_03270	ENOG4105CK1	PTS System
CEP89_03275	ENOG4105VZJ	PTS System
CEP89_03285	ENOG4105EMD	TRANSCRIPTIONal
CEP89_03290	ENOG4105BZG	amino acid carrier protein
CEP89_03295	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CEP89_03300	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CEP89_03305	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CEP89_03310	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CEP89_03315	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CEP89_03320	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CEP89_03325	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CEP89_03330	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CEP89_03335	ENOG4108BMY	protease
CEP89_03345	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
CEP89_03350	ENOG4105C5B	carbamate kinase
CEP89_03355	ENOG4105DBV	ornithine carbamoyltransferase
CEP89_03360	ENOG4105CEU	Arginine dihydrolase
CEP89_03440	ENOG41067MG	lrgb family
CEP89_03445	ENOG4105VAW	lrga family
CEP89_03450	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CEP89_03455	ENOG4105DQF	Hydrolase
CEP89_03460	ENOG4107QJT	sodium dicarboxylate symporter
CEP89_03465	ENOG4108BMY	protease
CEP89_03470	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
CEP89_03475	ENOG4105ETZ	PTS System
CEP89_03480	ENOG4105F3R	pts system mannose fructose sorbose family iid
CEP89_03500	ENOG4105E70	isomerase
CEP89_03505	ENOG4105CT8	Phosphorylase
CEP89_03515	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
CEP89_03535	ENOG4105D2M	Aldolase
CEP89_03550	ENOG4108IUW	ABC transporter
CEP89_03560	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CEP89_03595	ENOG4105EP8	Glycosyl Hydrolase Family 88
CEP89_03600	ENOG4105CBG	Sulfatase
CEP89_03605	ENOG4106AM8	polysaccharide lyase family 8
CEP89_03615	ENOG4105E0S	extracellular solute-binding protein family 1
CEP89_03620	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
CEP89_03630	ENOG4108IJ9	(ABC) transporter
CEP89_03635	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
CEP89_03640	ENOG4105CHR	reductase
CEP89_03645	ENOG4106AM8	polysaccharide lyase family 8
CEP89_03650	ENOG4108UHU	Aldolase
CEP89_03655	ENOG4105D7K	pfkb domain protein
CEP89_03660	ENOG4108M60	Transcriptional regulator
CEP89_03680	ENOG4105DM4	PTS System
CEP89_03685	ENOG4105DE4	1-phosphofructokinase
CEP89_03690	ENOG4105E98	transcriptional regulator DeoR family
CEP89_03710	ENOG4108URH	decarboxylase
CEP89_03720	ENOG4105EXC	Acyl-transferase
CEP89_03740	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CEP89_03750	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CEP89_03760	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CEP89_03765	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CEP89_03770	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CEP89_03785	ENOG4105D4A	Cell wall formation (By similarity)
CEP89_03790	ENOG4105DFU	Cell wall formation (By similarity)
CEP89_03835	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CEP89_03840	ENOG4107RUE	extracellular solute-binding protein family 1
CEP89_03850	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CEP89_03855	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
CEP89_03865	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CEP89_03870	ENOG4108IJ2	phosphate acetyltransferase
CEP89_03880	ENOG4105K8N	protein family UPF0079, ATPase
CEP89_03905	ENOG4105BZ1	(ABC) transporter
CEP89_03910	ENOG4108J59	Extracellular solute-binding protein, family 5
CEP89_03915	ENOG4108JQ7	(ABC) transporter
CEP89_03925	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CEP89_03930	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CEP89_03935	ENOG41068WN	
CEP89_03960	ENOG4108IUM	Glycogen debranching enzyme
CEP89_03975	ENOG4105C12	Phosphoribosylglycinamide synthetase
CEP89_03980	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CEP89_03985	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CEP89_03990	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CEP89_04000	ENOG4105C8V	SAICAR synthetase
CEP89_04010	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
CEP89_04015	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
CEP89_04025	ENOG4108JA2	transcriptioN-repair coupling factor
CEP89_04035	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CEP89_04040	ENOG410848D	S4 domain protein YaaA
CEP89_04045	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CEP89_04060	ENOG4105DKQ	ROK family
CEP89_04065	ENOG4105CI1	PTS System
CEP89_04070	ENOG4105D2N	Aldolase
CEP89_04090	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
CEP89_04095	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CEP89_04100	ENOG4105CNI	cell division protein FtsW
CEP89_04105	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CEP89_04110	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CEP89_04115	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
CEP89_04120	ENOG4105C5H	ABC transporter
CEP89_04130	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CEP89_04165	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CEP89_04170	ENOG4108UJD	30S ribosomal protein S9
CEP89_04190	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
CEP89_04195	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CEP89_04205	ENOG4105CKT	filamentous hemagglutinin
CEP89_04210	ENOG4105W5A	BNR Asp-box repeat protein
CEP89_04225	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
CEP89_04230	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CEP89_04250	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CEP89_04255	ENOG4105VUC	UPF0237 protein
CEP89_04260	ENOG4105CAG	UPF0210 protein
CEP89_04290	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CEP89_04315	ENOG4105EUR	Domain-Containing protein
CEP89_04330	ENOG4105EUR	Domain-Containing protein
CEP89_04335	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
CEP89_04345	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CEP89_04365	ENOG4105C0B	DNA polymerase III (alpha subunit)
CEP89_04380	ENOG4105M7K	Involved in the transcription termination process (By similarity)
CEP89_04390	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CEP89_04395	ENOG4105CDA	abc transporter atp-binding protein
CEP89_04400	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CEP89_04465	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
CEP89_04480	ENOG4108IQE	Amp-dependent synthetase and ligase
CEP89_04485	ENOG41082B1	30S ribosomal protein S16
CEP89_04500	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CEP89_04510	ENOG4107QHF	type ii secretion system protein e
CEP89_04520	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CEP89_04525	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CEP89_04530	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CEP89_04570	ENOG4105D07	Signal peptide peptidase, SppA
CEP89_04575	ENOG4105PGM	cation diffusion facilitator family transporter
CEP89_04585	ENOG4108YBP	pseudouridine synthase
CEP89_04590	ENOG4105DP4	dak2 domain fusion protein ylov
CEP89_04595	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CEP89_04605	ENOG4108Z4K	mutator MutT protein
CEP89_04615	ENOG4107QIV	Cytochrome c biogenesis protein
CEP89_04620	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEP89_04630	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CEP89_04650	ENOG4107QMH	DNA methylase
CEP89_04680	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CEP89_04700	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CEP89_04705	ENOG4105D4P	Coproporphyrinogen iii oxidase
CEP89_04735	ENOG4105DT3	PTS system, galactitol-specific IIc component
CEP89_04745	ENOG4105BZ1	(ABC) transporter
CEP89_04775	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CEP89_04780	ENOG4105CDE	UPF0348 protein
CEP89_04795	ENOG4105C19	ABC transporter
CEP89_04810	ENOG41086KC	Transcriptional regulator
CEP89_04815	ENOG4105CT4	transporter
CEP89_04820	ENOG4108HHA	Transketolase
CEP89_04825	ENOG4108IUS	Transketolase
CEP89_04845	ENOG4106R49	Methyltransferase
CEP89_04865	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CEP89_04880	ENOG4105DFF	Rod shape-determining protein mreb
CEP89_04885	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
CEP89_04890	ENOG4105FE9	pseudouridine synthase
CEP89_04915	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CEP89_04920	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
CEP89_04925	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CEP89_04930	ENOG4105CFG	Acts as a chaperone (By similarity)
CEP89_04940	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CEP89_04950	ENOG4105CID	antiterminator
CEP89_04955	ENOG4105C5Y	PTS System
CEP89_04965	ENOG4106ETB	IIa component
CEP89_04975	ENOG4105R6B	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
CEP89_04980	ENOG410863U	PTS System
CEP89_04985	ENOG4105C87	Aminotransferase class I and II
CEP89_05000	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CEP89_05010	ENOG4105CG3	alpha amylase, catalytic region
CEP89_05015	ENOG4105EUR	Domain-Containing protein
CEP89_05040	ENOG4105CG3	alpha amylase, catalytic region
CEP89_05045	ENOG4105CG3	alpha amylase, catalytic region
CEP89_05065	ENOG4105C7B	Threonine dehydratase
CEP89_05075	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CEP89_05085	ENOG4105DG6	mannose-6-phosphate isomerase
CEP89_05125	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
CEP89_05135	ENOG4106ETB	IIa component
CEP89_05140	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
CEP89_05145	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
CEP89_05175	ENOG4105F9F	transposase
CEP89_05195	ENOG4105D17	glycoside hydrolase, family 3 domain protein
CEP89_05200	ENOG4105CNT	hydrolase family 2
CEP89_05205	ENOG4105CT4	transporter
CEP89_05215	ENOG4105D2H	Uronic isomerase
CEP89_05220	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
CEP89_05225	ENOG4105DMW	Dehydrogenase reductase
CEP89_05230	ENOG41082BM	Transcriptional regulator, arsr family
CEP89_05250	ENOG4105ETZ	PTS System
CEP89_05255	ENOG4105F3R	pts system mannose fructose sorbose family iid
CEP89_05270	ENOG4105BZ1	(ABC) transporter
CEP89_05285	ENOG4107QYV	phosphohexose isomerase
CEP89_05305	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
CEP89_05315	ENOG4105CTZ	aminopeptidase c
CEP89_05320	ENOG4105CV8	reductase
CEP89_05335	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CEP89_05350	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CEP89_05355	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CEP89_05360	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CEP89_05365	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CEP89_05370	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CEP89_05375	ENOG41082SA	50s ribosomal protein l29
CEP89_05380	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CEP89_05385	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CEP89_05395	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CEP89_05400	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CEP89_05405	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CEP89_05410	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CEP89_05415	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CEP89_05420	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CEP89_05425	ENOG41085P3	50S ribosomal protein L30
CEP89_05430	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CEP89_05450	ENOG41082I2	s4 domain protein
CEP89_05460	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CEP89_05465	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CEP89_05485	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CEP89_05490	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CEP89_05515	ENOG4105DSE	periplasmic solute binding protein
CEP89_05520	ENOG4105CE4	GlcNAc 6-P deacetylase
CEP89_05525	ENOG4105PZN	Type II restriction enzyme NlaIV
CEP89_05535	ENOG4105C59	p-type ATPase
CEP89_05565	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
CEP89_05585	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
CEP89_05590	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
CEP89_05595	ENOG4105D6F	Phosphatase
CEP89_05600	ENOG4108DBC	nitroreductase
CEP89_05630	ENOG4105DC7	peptidase M24
CEP89_05640	ENOG4105BZ1	(ABC) transporter
CEP89_05645	ENOG4105BZ1	(ABC) transporter
CEP89_05665	ENOG4107RUY	(E1 component), alpha subunit
CEP89_05670	ENOG4105CPP	Dehydrogenase, E1 component
CEP89_05675	ENOG4107QKR	Dehydrogenase
CEP89_05685	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
CEP89_05690	ENOG4105DF9	Lipoate-protein, ligase
CEP89_05705	ENOG4105ETX	regulatoR
CEP89_05715	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
CEP89_05720	ENOG4105F23	Fibronectin-binding protein
CEP89_05730	ENOG4105DJV	ribulose-phosphate 3-epimerase
CEP89_05735	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CEP89_05970	ENOG4105KCK	Peptidoglycan-associated lipoprotein
CEP89_05980	ENOG4107TT5	NLP P60 protein
CEP89_06005	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CEP89_06015	ENOG4105F0S	class B acid phosphatase
CEP89_06020	ENOG4108QZZ	filamentous hemagglutinin
CEP89_06040	ENOG4105CKT	filamentous hemagglutinin
CEP89_06085	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
CEP89_06090	ENOG4108HHA	Transketolase
CEP89_06095	ENOG4108IUS	Transketolase
CEP89_06100	ENOG4105CJ1	ABC, transporter
CEP89_06110	ENOG4108UZ3	Transporter
CEP89_06115	ENOG4105C3K	feS assembly ATPase SufC
CEP89_06125	ENOG4105JRK	feS assembly protein SufD
CEP89_06130	ENOG4105C9B	Cysteine desulfurase
CEP89_06185	ENOG410615F	Integral membrane protein (intg_mem_TP0381)
CEP89_06190	ENOG4105CWE	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CEP89_06205	ENOG4105D3R	alkyl hydroperoxide reductase
CEP89_06210	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
CEP89_06225	ENOG4105DPN	Oligoendopeptidase f
CEP89_06245	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CEP89_06250	ENOG4108B02	Modulates RecA activity (By similarity)
CEP89_06255	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CEP89_06260	ENOG4105CB5	ATP-dependent DNA helicase recG
CEP89_06310	ENOG4105CSA	Coproporphyrinogen iii oxidase
CEP89_06320	ENOG4105BZ1	(ABC) transporter
CEP89_06325	ENOG4105BZ1	(ABC) transporter
CEP89_06335	ENOG4105C2M	dna polymerase I
CEP89_06340	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CEP89_06350	ENOG4105C34	Pseudouridine synthase
CEP89_06370	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CEP89_06375	ENOG4107TEJ	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CEP89_06380	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
CEP89_06385	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
CEP89_06395	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CEP89_06410	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
CEP89_06415	ENOG4105CJN	penicillin-binding protein
CEP89_06420	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CEP89_06440	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
CEP89_06450	ENOG4105CPF	Cell wall formation (By similarity)
CEP89_06460	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
CEP89_06465	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CEP89_06490	ENOG4107YH3	SUF system FeS assembly protein, NifU family
CEP89_06495	ENOG410805Y	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CEP89_06500	ENOG4105CUT	histidyl-tRNA synthetase
CEP89_06505	ENOG4105C9M	aspartyl-trna synthetase
CEP89_06520	ENOG4108BMY	protease
CEP89_06525	ENOG4105E9M	CRISPR-associated protein, Csn1 family
CEP89_06535	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
CEP89_06545	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CEP89_06550	ENOG4105C6N	Formate acetyltransferase
CEP89_06555	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
CEP89_06570	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CEP89_06575	ENOG4105KME	endoribonuclease L-psp
CEP89_06580	ENOG4108EKI	Dehydrogenase
CEP89_06590	ENOG4105QEK	Transcriptional regulator
CEP89_06595	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
CEP89_06605	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CEP89_06620	ENOG4105DRS	transport system, permease
CEP89_06635	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CEP89_06650	ENOG4107YVC	modification (methylase)
CEP89_06655	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
CEP89_06670	ENOG4105CRK	lysyL-tRNA synthetase
CEP89_06705	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CEP89_06720	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CEP89_06750	ENOG4105CBX	hi0933 family
CEP89_06755	ENOG4105DZ0	fad dependent oxidoreductase
CEP89_06780	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
CEP89_06785	ENOG4107TT5	NLP P60 protein
CEP89_06795	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CEP89_06815	ENOG4105C4X	radical SAM domain protein
CEP89_06825	ENOG4108IXY	short-chain dehydrogenase reductase
CEP89_06830	ENOG4107WA9	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CEP89_06840	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
CEP89_06860	ENOG4105GSQ	TM1410 hypothetical-related protein
CEP89_06865	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CEP89_06870	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CEP89_06875	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CEP89_06880	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CEP89_06890	ENOG4105UQX	Mate efflux family protein
CEP89_06895	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
CEP89_06905	ENOG4105DZP	Membrane-associated zinc metalloprotease
CEP89_06920	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CEP89_06935	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CEP89_06940	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CEP89_06955	ENOG4105C2W	permease
CEP89_06975	ENOG4107QKW	extracellular solute-binding protein family 1
CEP89_06985	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CEP89_06995	ENOG4106KNT	transcriptional regulator
CEP89_07020	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CEP89_07035	ENOG4105C4R	Atp-dependent dna helicase
CEP89_07070	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
CEP89_07085	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
CEP89_07090	ENOG4105CZN	Potassium uptake protein
CEP89_07100	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CEP89_07105	ENOG4105CN5	Metallo-Beta-Lactamase
CEP89_07110	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
CEP89_07115	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CEP89_07120	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CEP89_07125	ENOG4105CU9	asparagine synthetase A
CEP89_07140	ENOG4108JQ7	(ABC) transporter
CEP89_07145	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CEP89_07150	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CEP89_07155	ENOG4105DC7	peptidase M24
CEP89_07175	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
CEP89_07180	ENOG4105D48	metallophosphoesterase
CEP89_07185	ENOG4105CAT	Cytidine monophosphate kinase
CEP89_07190	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CEP89_07200	ENOG4105C1V	Peptidase, M16
CEP89_07205	ENOG4105CNI	cell division protein FtsW
CEP89_07210	ENOG4105EI2	Pseudouridine synthase
CEP89_07215	ENOG4105VEQ	Cold shock protein
CEP89_07220	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CEP89_07225	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CEP89_07245	ENOG4105F32	YngK protein
CEP89_07250	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CEP89_07255	ENOG41080E8	Transcriptional regulator, Spx MgsR family
CEP89_07260	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CEP89_07265	ENOG4107YWA	deoxycytidylate deaminase
CEP89_07270	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
CEP89_07290	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CEP89_07295	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CEP89_07445	ENOG4105K60	Virulence-associated protein D
CEP89_07480	ENOG4105KCK	Peptidoglycan-associated lipoprotein
CEP89_07490	ENOG4107TT5	NLP P60 protein
CEP89_07515	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CEP89_07520	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CEP89_07565	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CEP89_07580	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CEP89_07585	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CEP89_07590	ENOG4108WTY	tRNA (Guanine-N(1)-)-methyltransferase
CEP89_07595	ENOG4105VDH	Dihydroxyacetone kinase
CEP89_07605	ENOG41081RY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CEP89_07610	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CEP89_07620	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CEP89_07645	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CEP89_07650	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
CEP89_07660	ENOG41081EM	Involved in DNA repair and RecF pathway recombination (By similarity)
CEP89_07665	ENOG4105DM4	PTS System
CEP89_07670	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CEP89_07690	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CEP89_07695	ENOG4105MS2	ribosomal subunit Interface protein
CEP89_07705	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CEP89_07715	ENOG4105BZF	Glycosyl transferase (Group 1