locus-tag	class	description
SaSA209_0002	COG0592	DNA-directed DNA polymerase activity
SaSA209_0005	COG0012	GTP binding
SaSA209_0006	COG0193	aminoacyl-tRNA hydrolase activity
SaSA209_0008	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SaSA209_0011	COG0037	tRNA processing
SaSA209_0013	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SaSA209_0022	COG2801	Transposase and inactivated derivatives
SaSA209_0027	COG1695	Transcriptional regulator
SaSA209_0030	COG1755	Isoprenylcysteine carboxyl methyltransferase
SaSA209_0034	COG4224	UPF0291 protein
SaSA209_0037	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA209_0038	COG0446	pyridine nucleotide-disulphide oxidoreductase
SaSA209_0044	COG1131	(ABC) transporter
SaSA209_0046	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA209_0046	COG2190	(PTS) system
SaSA209_0046	COG1263	PTS System
SaSA209_0048	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SaSA209_0049	COG0275	rRNA processing
SaSA209_0051	COG0768	penicillin binding
SaSA209_0053	COG0513	Belongs to the DEAD box helicase family
SaSA209_0056	COG1126	abc transporter atp-binding protein
SaSA209_0058	COG0492	ferredoxin-NADP+ reductase activity
SaSA209_0059	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SaSA209_0062	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaSA209_0064	COG4474	Belongs to the UPF0398 family
SaSA209_0066	COG0116	Belongs to the methyltransferase superfamily
SaSA209_0070	COG1131	(ABC) transporter
SaSA209_0078	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SaSA209_0080	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SaSA209_0080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SaSA209_0082	COG0515	serine threonine protein kinase
SaSA209_0082	COG2815	serine threonine protein kinase
SaSA209_0084	COG4585	Histidine kinase
SaSA209_0085	COG2197	response regulator
SaSA209_0087	COG1098	S1 RNA binding domain
SaSA209_0089	COG1349	DNA-binding transcription factor activity
SaSA209_0091	COG1447	Phosphotransferase system cellobiose-specific component IIA
SaSA209_0095	COG1739	Uncharacterized protein family UPF0029
SaSA209_0096	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SaSA209_0097	COG1040	competence protein
SaSA209_0099	COG0527	aspartate kinase activity
SaSA209_0101	COG1024	Enoyl-CoA hydratase
SaSA209_0105	COG2070	2-Nitropropane dioxygenase
SaSA209_0106	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SaSA209_0107	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA209_0108	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SaSA209_0111	COG0439	Biotin carboxylase
SaSA209_0118	COG3716	PTS system mannose fructose sorbose family IID component
SaSA209_0119	COG3715	PTS system
SaSA209_0121	COG0561	phosphatase activity
SaSA209_0124	COG2252	PERMEase
SaSA209_0125	COG0802	atpase or kinase
SaSA209_0127	COG1316	TRANSCRIPTIONal
SaSA209_0129	COG0537	adenosine 5'-monophosphoramidase activity
SaSA209_0131	COG1131	(ABC) transporter
SaSA209_0132	COG4473	ABC transporter
SaSA209_0136	COG0195	Participates in both transcription termination and antitermination
SaSA209_0137	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SaSA209_0145	COG2860	membrane
SaSA209_0147	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaSA209_0147	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaSA209_0148	COG1832	CoA-binding protein
SaSA209_0154	COG1268	BioY protein
SaSA209_0155	COG1234	tRNA 3'-trailer cleavage
SaSA209_0158	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SaSA209_0159	COG0457	Tetratricopeptide repeat
SaSA209_0159	COG0705	Rhomboid family
SaSA209_0160	COG1744	ABC transporter substrate-binding protein PnrA-like
SaSA209_0161	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SaSA209_0164	COG0706	membrane insertase activity
SaSA209_0167	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SaSA209_0168	COG0436	Aminotransferase
SaSA209_0169	COG1381	Involved in DNA repair and RecF pathway recombination
SaSA209_0170	COG2801	Transposase and inactivated derivatives
SaSA209_0173	COG0416	fatty acid biosynthetic process
SaSA209_0174	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SaSA209_0175	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SaSA209_0176	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SaSA209_0179	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SaSA209_0186	COG1175	transmembrane transport
SaSA209_0188	COG0395	ABC-type sugar transport system, permease component
SaSA209_0191	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SaSA209_0194	COG1737	Transcriptional regulator
SaSA209_0196	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SaSA209_0201	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SaSA209_0204	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SaSA209_0206	COG2755	lipolytic protein G-D-S-L family
SaSA209_0206	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SaSA209_0207	COG1012	belongs to the aldehyde dehydrogenase family
SaSA209_0207	COG1454	alcohol dehydrogenase
SaSA209_0208	COG1064	alcohol dehydrogenase
SaSA209_0210	COG0534	Mate efflux family protein
SaSA209_0232	COG0201	protein transport
SaSA209_0233	COG0563	adenylate kinase activity
SaSA209_0235	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SaSA209_0238	COG0202	RNA polymerase activity
SaSA209_0242	COG1121	(ABC) transporter
SaSA209_0243	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SaSA209_0245	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SaSA209_0246	COG4499	WXG100 protein secretion system (Wss), protein YukC
SaSA209_0246	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaSA209_0250	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SaSA209_0251	COG1459	type II secretion system
SaSA209_0259	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SaSA209_0260	COG1363	Peptidase, m42
SaSA209_0263	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SaSA209_0264	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA209_0267	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SaSA209_0268	COG3275	phosphorelay sensor kinase activity
SaSA209_0269	COG3279	Response regulator of the LytR AlgR family
SaSA209_0271	COG1346	cytolysis
SaSA209_0273	COG0601	transmembrane transport
SaSA209_0274	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA209_0275	COG1122	ATPase activity
SaSA209_0282	COG3959	Transketolase, thiamine diphosphate binding domain
SaSA209_0287	COG1045	serine acetyltransferase
SaSA209_0289	COG0215	cysteine-tRNA ligase activity
SaSA209_0290	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SaSA209_0295	COG1476	TRANSCRIPTIONal
SaSA209_0296	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SaSA209_0307	COG1396	sequence-specific DNA binding
SaSA209_0310	COG1732	Glycine betaine
SaSA209_0320	COG1705	Flagellar rod assembly protein muramidase FlgJ
SaSA209_0325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SaSA209_0327	COG0351	phosphomethylpyrimidine kinase
SaSA209_0328	COG4720	Psort location CytoplasmicMembrane, score
SaSA209_0329	COG4475	Protein of unknown function (DUF436)
SaSA209_0330	COG0668	transmembrane transport
SaSA209_0335	COG0756	dUTP diphosphatase activity
SaSA209_0338	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SaSA209_0339	COG2801	Transposase and inactivated derivatives
SaSA209_0341	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SaSA209_0342	COG1879	ABC-type sugar transport system periplasmic component
SaSA209_0343	COG1172	Belongs to the binding-protein-dependent transport system permease family
SaSA209_0346	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SaSA209_0347	COG1609	Transcriptional regulator
SaSA209_0348	COG0577	efflux transmembrane transporter activity
SaSA209_0349	COG1136	(ABC) transporter
SaSA209_0351	COG5002	protein histidine kinase activity
SaSA209_0353	COG0165	Argininosuccinate lyase
SaSA209_0354	COG0191	fructose-bisphosphate aldolase activity
SaSA209_0358	COG1461	Dihydroxyacetone kinase
SaSA209_0362	COG1126	abc transporter atp-binding protein
SaSA209_0363	COG0765	amino acid transport
SaSA209_0365	COG1968	undecaprenyl-diphosphatase activity
SaSA209_0366	COG4862	establishment of competence for transformation
SaSA209_0367	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SaSA209_0369	COG0719	Fe-S assembly protein
SaSA209_0370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SaSA209_0372	COG0719	Fe-S assembly protein
SaSA209_0373	COG1686	Belongs to the peptidase S11 family
SaSA209_0374	COG1686	Belongs to the peptidase S11 family
SaSA209_0375	COG4166	transmembrane transport
SaSA209_0376	COG0601	transmembrane transport
SaSA209_0377	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA209_0378	COG0444	Belongs to the ABC transporter superfamily
SaSA209_0379	COG4608	Belongs to the ABC transporter superfamily
SaSA209_0381	COG2137	regulation of response to DNA damage stimulus
SaSA209_0382	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SaSA209_0384	COG2153	protein acetylation
SaSA209_0386	COG1442	glycosyl transferase family 8
SaSA209_0386	COG1216	Glycosyl transferase, family 2
SaSA209_0396	COG0789	Transcriptional regulator
SaSA209_0397	COG1063	alcohol dehydrogenase
SaSA209_0398	COG0656	L-ascorbic acid biosynthetic process
SaSA209_0405	COG2226	methyltransferase
SaSA209_0407	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaSA209_0408	COG3414	Phosphotransferase system galactitol-specific IIB component
SaSA209_0409	COG3775	system Galactitol-specific IIC component
SaSA209_0410	COG0235	Class ii aldolase
SaSA209_0412	COG3775	system Galactitol-specific IIC component
SaSA209_0413	COG3414	Phosphotransferase system galactitol-specific IIB component
SaSA209_0414	COG2207	Transcriptional regulator
SaSA209_0417	COG0395	ABC-type sugar transport system, permease component
SaSA209_0421	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SaSA209_0437	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SaSA209_0440	COG2315	Protein conserved in bacteria
SaSA209_0443	COG0742	ribosomal rna small subunit methyltransferase
SaSA209_0446	COG3480	Lon protease (S16) C-terminal proteolytic domain
SaSA209_0448	COG4470	Protein conserved in bacteria
SaSA209_0452	COG1132	(ABC) transporter
SaSA209_0453	COG0512	Glutamine amidotransferase of anthranilate synthase
SaSA209_0454	COG1268	BioY protein
SaSA209_0455	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SaSA209_0459	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SaSA209_0471	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SaSA209_0473	COG0762	integral membrane protein
SaSA209_0474	COG2302	S4 RNA-binding domain
SaSA209_0475	COG3599	regulation of cell shape
SaSA209_0479	COG0542	response to heat
SaSA209_0480	COG4703	Protein of unknown function (DUF1797)
SaSA209_0481	COG0765	amino acid transport
SaSA209_0482	COG1126	abc transporter atp-binding protein
SaSA209_0483	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SaSA209_0485	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SaSA209_0486	COG1570	exodeoxyribonuclease VII activity
SaSA209_0489	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SaSA209_0490	COG1438	arginine binding
SaSA209_0491	COG0497	DNA recombination
SaSA209_0492	COG1307	EDD domain protein, DegV family
SaSA209_0493	COG2755	lipolytic protein G-D-S-L family
SaSA209_0502	COG1078	dGTPase activity
SaSA209_0507	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SaSA209_0509	COG2884	Cell division ATP-binding protein ftsE
SaSA209_0510	COG2177	Part of the ABC transporter FtsEX involved in
SaSA209_0514	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SaSA209_0514	COG1199	ATP-dependent helicase activity
SaSA209_0515	COG0436	Aminotransferase
SaSA209_0525	COG0254	rRNA binding
SaSA209_0526	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SaSA209_0527	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SaSA209_0528	COG0716	FMN binding
SaSA209_0529	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SaSA209_0529	COG1605	Chorismate mutase
SaSA209_0532	COG0772	Belongs to the SEDS family
SaSA209_0543	COG1316	TRANSCRIPTIONal
SaSA209_0544	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SaSA209_0546	COG3942	CHAP domain
SaSA209_0546	COG1705	Flagellar rod assembly protein muramidase FlgJ
SaSA209_0570	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SaSA209_0574	COG1131	(ABC) transporter
SaSA209_0587	COG1136	(ABC) transporter
SaSA209_0590	COG0586	Pfam SNARE associated Golgi protein
SaSA209_0591	COG4619	ABC transporter
SaSA209_0592	COG0390	transport system, permease component
SaSA209_0594	COG0583	DNA-binding transcription factor activity
SaSA209_0596	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA209_0598	COG2211	Major facilitator Superfamily
SaSA209_0599	COG3250	beta-galactosidase activity
SaSA209_0600	COG2186	Transcriptional regulator
SaSA209_0603	COG1609	Transcriptional regulator
SaSA209_0606	COG0438	transferase activity, transferring glycosyl groups
SaSA209_0611	COG0765	amino acid transport
SaSA209_0612	COG0765	amino acid transport
SaSA209_0613	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA209_0614	COG1126	abc transporter atp-binding protein
SaSA209_0615	COG0745	RESPONSE REGULATOR receiver
SaSA209_0616	COG5002	protein histidine kinase activity
SaSA209_0617	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SaSA209_0618	COG2832	Protein of unknown function (DUF454)
SaSA209_0620	COG1196	nuclear chromosome segregation
SaSA209_0622	COG0552	protein localization to endoplasmic reticulum
SaSA209_0624	COG2801	Transposase and inactivated derivatives
SaSA209_0625	COG3689	TIGRFAM TIGR03943 family protein
SaSA209_0626	COG0701	Predicted permease
SaSA209_0629	COG2183	response to ionizing radiation
SaSA209_0630	COG3091	SprT-like family
SaSA209_0631	COG1983	PspC domain protein
SaSA209_0639	COG4443	Transcriptional Coactivator p15 (PC4)
SaSA209_0641	COG1914	H( )-stimulated, divalent metal cation uptake system
SaSA209_0646	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SaSA209_0649	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SaSA209_0656	COG0772	Belongs to the SEDS family
SaSA209_0660	COG0768	penicillin binding
SaSA209_0663	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SaSA209_0668	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SaSA209_0669	COG2011	ABC-type metal ion transport system permease component
SaSA209_0670	COG1464	Belongs to the NlpA lipoprotein family
SaSA209_0671	COG0513	Belongs to the DEAD box helicase family
SaSA209_0673	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SaSA209_0674	COG0204	Acyl-transferase
SaSA209_0675	COG1555	photosystem II stabilization
SaSA209_0675	COG1596	polysaccharide export
SaSA209_0678	COG1609	Transcriptional regulator
SaSA209_0679	COG0657	acetylesterase activity
SaSA209_0680	COG2264	protein methyltransferase activity
SaSA209_0682	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SaSA209_0683	COG3711	transcriptional antiterminator
SaSA209_0684	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA209_0684	COG1263	PTS System
SaSA209_0684	COG2190	(PTS) system
SaSA209_0686	COG2801	Transposase and inactivated derivatives
SaSA209_0688	COG3835	regulator
SaSA209_0689	COG1929	Belongs to the glycerate kinase type-1 family
SaSA209_0690	COG2610	gluconate transmembrane transporter activity
SaSA209_0692	COG1846	Transcriptional regulator
SaSA209_0693	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SaSA209_0696	COG0435	Glutathione S-transferase
SaSA209_0697	COG1187	pseudouridine synthase activity
SaSA209_0701	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SaSA209_0704	COG4894	glucomannan catabolic process
SaSA209_0705	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SaSA209_0707	COG1442	glycosyl transferase family 8
SaSA209_0711	COG1476	TRANSCRIPTIONal
SaSA209_0715	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SaSA209_0716	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SaSA209_0717	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SaSA209_0720	COG1012	belongs to the aldehyde dehydrogenase family
SaSA209_0721	COG0726	polysaccharide deacetylase
SaSA209_0723	COG2801	Transposase and inactivated derivatives
SaSA209_0724	COG0513	Belongs to the DEAD box helicase family
SaSA209_0726	COG1956	GAF domain-containing protein
SaSA209_0727	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SaSA209_0729	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SaSA209_0736	COG4721	ABC-type cobalt transport system, permease component
SaSA209_0737	COG1122	ATPase activity
SaSA209_0739	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SaSA209_0741	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SaSA209_0742	COG0352	thiamine-phosphate diphosphorylase activity
SaSA209_0743	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SaSA209_0745	COG4109	DRTGG domain
SaSA209_0746	COG0024	Methionine aminopeptidase
SaSA209_0749	COG4708	membrane
SaSA209_0750	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SaSA209_0751	COG1597	lipid kinase activity
SaSA209_0752	COG1523	belongs to the glycosyl hydrolase 13 family
SaSA209_0753	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SaSA209_0758	COG0356	it plays a direct role in the translocation of protons across the membrane
SaSA209_0760	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SaSA209_0764	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SaSA209_0766	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SaSA209_0771	COG0072	phenylalanine-tRNA ligase activity
SaSA209_0771	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA209_0772	COG2321	neutral zinc metallopeptidase
SaSA209_0774	COG1074	ATP-dependent DNA helicase activity
SaSA209_0776	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SaSA209_0777	COG0488	(ABC) transporter
SaSA209_0778	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SaSA209_0779	COG0508	dehydrogenase complex catalyzes the overall conversion of
SaSA209_0779	COG0022	dehydrogenase e1 component
SaSA209_0780	COG0508	dehydrogenase complex catalyzes the overall conversion of
SaSA209_0782	COG0095	Lipoate-protein ligase
SaSA209_0783	COG3442	glutamine amidotransferase
SaSA209_0784	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SaSA209_0785	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SaSA209_0790	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SaSA209_0794	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
SaSA209_0795	COG1518	maintenance of DNA repeat elements
SaSA209_0796	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SaSA209_0804	COG1418	mRNA catabolic process
SaSA209_0805	COG0456	acetyltransferase
SaSA209_0807	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SaSA209_0810	COG0398	Pfam SNARE associated Golgi protein
SaSA209_0812	COG1131	(ABC) transporter
SaSA209_0813	COG1725	Transcriptional regulator
SaSA209_0816	COG0469	pyruvate kinase activity
SaSA209_0817	COG0681	Belongs to the peptidase S26 family
SaSA209_0818	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SaSA209_0819	COG2824	Alkylphosphonate utilization operon protein PhnA
SaSA209_0820	COG0765	amino acid transport
SaSA209_0821	COG1126	abc transporter atp-binding protein
SaSA209_0824	COG2801	Transposase and inactivated derivatives
SaSA209_0827	COG2813	Specifically methylates the guanine in position
SaSA209_0835	COG3764	Sortase (surface protein transpeptidase)
SaSA209_0836	COG0346	lactoylglutathione lyase activity
SaSA209_0841	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SaSA209_0843	COG1464	Belongs to the NlpA lipoprotein family
SaSA209_0846	COG1136	(ABC) transporter
SaSA209_0848	COG0745	RESPONSE REGULATOR receiver
SaSA209_0849	COG5002	protein histidine kinase activity
SaSA209_0854	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SaSA209_0855	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SaSA209_0856	COG5002	protein histidine kinase activity
SaSA209_0857	COG0745	RESPONSE REGULATOR receiver
SaSA209_0859	COG0704	Plays a role in the regulation of phosphate uptake
SaSA209_0862	COG0581	inorganic phosphate transmembrane transporter activity
SaSA209_0863	COG0573	inorganic phosphate transmembrane transporter activity
SaSA209_0864	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SaSA209_0866	COG0483	inositol monophosphate 1-phosphatase activity
SaSA209_0867	COG4476	Belongs to the UPF0223 family
SaSA209_0868	COG1393	Belongs to the ArsC family
SaSA209_0869	COG0196	riboflavin kinase activity
SaSA209_0876	COG1136	(ABC) transporter
SaSA209_0877	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SaSA209_0878	COG0758	DNA mediated transformation
SaSA209_0879	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SaSA209_0880	COG4604	ABC transporter, ATP-binding protein
SaSA209_0881	COG4605	iron ion homeostasis
SaSA209_0882	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaSA209_0883	COG0110	maltose O-acetyltransferase activity
SaSA209_0885	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SaSA209_0886	COG1376	ErfK ybiS ycfS ynhG family protein
SaSA209_0887	COG1966	Carbon starvation protein
SaSA209_0888	COG3279	Response regulator of the LytR AlgR family
SaSA209_0889	COG3275	phosphorelay sensor kinase activity
SaSA209_0897	COG0505	Belongs to the CarA family
SaSA209_0899	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SaSA209_0900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SaSA209_0903	COG0488	(ABC) transporter
SaSA209_0905	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SaSA209_0908	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SaSA209_0909	COG2801	Transposase and inactivated derivatives
SaSA209_0918	COG0095	Lipoate-protein ligase
SaSA209_0920	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SaSA209_0921	COG4684	Psort location CytoplasmicMembrane, score
SaSA209_0922	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SaSA209_0923	COG2801	Transposase and inactivated derivatives
SaSA209_0932	COG2890	protein-(glutamine-N5) methyltransferase activity
SaSA209_0940	COG2233	PERMEase
SaSA209_0943	COG0477	Major facilitator Superfamily
SaSA209_0948	COG0564	pseudouridine synthase activity
SaSA209_0949	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SaSA209_0950	COG2357	RelA SpoT domain protein
SaSA209_0952	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SaSA209_0953	COG1104	cysteine desulfurase activity
SaSA209_0957	COG0628	permease
SaSA209_0958	COG2723	6-phospho-beta-galactosidase activity
SaSA209_0968	COG0561	phosphatase activity
SaSA209_0973	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SaSA209_0974	COG1177	transmembrane transport
SaSA209_0975	COG1176	ABC-type spermidine putrescine transport system, permease component I
SaSA209_0982	COG0285	dihydrofolate synthase activity
SaSA209_0983	COG2962	Rard protein
SaSA209_0987	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SaSA209_0995	COG2801	Transposase and inactivated derivatives
SaSA209_1005	COG2261	transglycosylase associated protein
SaSA209_1010	COG1115	amino acid carrier protein
SaSA209_1011	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SaSA209_1013	COG1346	cytolysis
SaSA209_1015	COG0539	negative regulation of cytoplasmic translation
SaSA209_1017	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SaSA209_1019	COG0187	DNA topoisomerase II activity
SaSA209_1020	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SaSA209_1026	COG2089	acid synthase
SaSA209_1030	COG1442	glycosyl transferase family 8
SaSA209_1030	COG1216	Glycosyl transferase, family 2
SaSA209_1033	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SaSA209_1034	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SaSA209_1038	COG1316	TRANSCRIPTIONal
SaSA209_1048	COG3842	ATPase activity
SaSA209_1052	COG3527	Alpha-acetolactate decarboxylase
SaSA209_1053	COG0028	Belongs to the TPP enzyme family
SaSA209_1054	COG0457	Tetratricopeptide repeat
SaSA209_1055	COG0628	permease
SaSA209_1057	COG1051	belongs to the nudix hydrolase family
SaSA209_1058	COG5492	domain, Protein
SaSA209_1059	COG1088	dTDP-glucose 4,6-dehydratase activity
SaSA209_1061	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SaSA209_1062	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SaSA209_1064	COG2384	SAM-dependent methyltransferase
SaSA209_1066	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SaSA209_1068	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SaSA209_1068	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SaSA209_1069	COG0300	oxidoreductase activity
SaSA209_1073	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SaSA209_1079	COG1573	uracil-dna glycosylase
SaSA209_1080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SaSA209_1082	COG0584	glycerophosphoryl diester phosphodiesterase
SaSA209_1085	COG0534	Mate efflux family protein
SaSA209_1090	COG1136	(ABC) transporter
SaSA209_1096	COG0833	amino acid
SaSA209_1103	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SaSA209_1105	COG3425	synthase
SaSA209_1108	COG1272	protein, Hemolysin III
SaSA209_1117	COG0745	RESPONSE REGULATOR receiver
SaSA209_1118	COG2357	RelA SpoT domain protein
SaSA209_1119	COG1132	(ABC) transporter
SaSA209_1121	COG1132	(ABC) transporter
SaSA209_1122	COG1132	(ABC) transporter
SaSA209_1124	COG0488	(ABC) transporter
SaSA209_1125	COG0617	tRNA 3'-terminal CCA addition
SaSA209_1130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaSA209_1130	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaSA209_1130	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaSA209_1131	COG1105	Belongs to the carbohydrate kinase PfkB family
SaSA209_1132	COG1349	DNA-binding transcription factor activity
SaSA209_1139	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SaSA209_1141	COG1837	Belongs to the UPF0109 family
SaSA209_1143	COG0577	efflux transmembrane transporter activity
SaSA209_1144	COG1136	(ABC) transporter
SaSA209_1145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SaSA209_1147	COG0505	Belongs to the CarA family
SaSA209_1149	COG0564	pseudouridine synthase activity
SaSA209_1151	COG0583	DNA-binding transcription factor activity
SaSA209_1152	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SaSA209_1157	COG0301	tRNA thio-modification
SaSA209_1158	COG1104	cysteine desulfurase activity
SaSA209_1160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SaSA209_1166	COG1368	sulfuric ester hydrolase activity
SaSA209_1175	COG2244	polysaccharide biosynthetic process
SaSA209_1176	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SaSA209_1177	COG1120	ATPase activity
SaSA209_1184	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SaSA209_1185	COG1253	flavin adenine dinucleotide binding
SaSA209_1186	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SaSA209_1187	COG1242	4 iron, 4 sulfur cluster binding
SaSA209_1188	COG0671	phosphoesterase, PA-phosphatase related
SaSA209_1189	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SaSA209_1195	COG0681	Belongs to the peptidase S26 family
SaSA209_1197	COG0297	glycogen (starch) synthase activity
SaSA209_1205	COG3475	LICD family
SaSA209_1208	COG0463	Glycosyl transferase, family 2
SaSA209_1209	COG1215	transferase activity, transferring glycosyl groups
SaSA209_1211	COG1091	dTDP-4-dehydrorhamnose reductase activity
SaSA209_1212	COG2151	metal-sulfur cluster biosynthetic enzyme
SaSA209_1213	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SaSA209_1214	COG0358	DNA primase activity
SaSA209_1215	COG1970	mechanosensitive ion channel activity
SaSA209_1218	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA209_1219	COG0004	ammonium transporteR
SaSA209_1223	COG2271	Major facilitator Superfamily
SaSA209_1224	COG0058	SHG alpha-glucan phosphorylase activity
SaSA209_1225	COG1640	4-alpha-glucanotransferase
SaSA209_1226	COG1609	Transcriptional regulator
SaSA209_1228	COG1175	transmembrane transport
SaSA209_1229	COG3833	ABC-type maltose transport systems, permease component
SaSA209_1230	COG3104	oligopeptide transport
SaSA209_1231	COG2801	Transposase and inactivated derivatives
SaSA209_1237	COG0438	transferase activity, transferring glycosyl groups
SaSA209_1248	COG0765	amino acid transport
SaSA209_1249	COG1126	abc transporter atp-binding protein
SaSA209_1254	COG2309	aminopeptidase activity
SaSA209_1257	COG1187	pseudouridine synthase activity
SaSA209_1258	COG0656	L-ascorbic acid biosynthetic process
SaSA209_1259	COG0778	Nitroreductase
SaSA209_1260	COG0346	lactoylglutathione lyase activity
SaSA209_1261	COG0463	Glycosyl transferase, family 2
SaSA209_1262	COG1113	amino acid transport
SaSA209_1264	COG0557	exoribonuclease II activity
SaSA209_1266	COG2814	Major facilitator Superfamily
SaSA209_1268	COG1131	(ABC) transporter
SaSA209_1277	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SaSA209_1282	COG1702	phosphate starvation-inducible protein PhoH
SaSA209_1290	COG0444	Belongs to the ABC transporter superfamily
SaSA209_1291	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA209_1292	COG0601	transmembrane transport
SaSA209_1293	COG0747	negative chemotaxis
SaSA209_1295	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SaSA209_1297	COG1473	amidohydrolase
SaSA209_1298	COG0583	DNA-binding transcription factor activity
SaSA209_1301	COG1674	ftsk spoiiie
SaSA209_1302	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SaSA209_1308	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SaSA209_1313	COG0673	inositol 2-dehydrogenase activity
SaSA209_1316	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA209_1320	COG1215	transferase activity, transferring glycosyl groups
SaSA209_1327	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA209_1327	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA209_1330	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SaSA209_1332	COG0708	Exodeoxyribonuclease III
SaSA209_1333	COG1393	Belongs to the ArsC family
SaSA209_1334	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SaSA209_1335	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA209_1337	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SaSA209_1341	COG0470	DNA polymerase III
SaSA209_1343	COG0517	IMP dehydrogenase activity
SaSA209_1344	COG0410	ABC transporter
SaSA209_1345	COG0411	ABC transporter
SaSA209_1347	COG0559	Belongs to the binding-protein-dependent transport system permease family
SaSA209_1352	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SaSA209_1354	COG0531	amino acid
SaSA209_1358	COG2801	Transposase and inactivated derivatives
SaSA209_1360	COG1187	pseudouridine synthase activity
SaSA209_1366	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SaSA209_1367	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SaSA209_1370	COG1827	regulation of RNA biosynthetic process
SaSA209_1373	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SaSA209_1374	COG1254	Belongs to the acylphosphatase family
SaSA209_1376	COG0765	amino acid transport
SaSA209_1377	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA209_1380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SaSA209_1384	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SaSA209_1386	COG1484	DNA-dependent DNA replication
SaSA209_1389	COG5002	protein histidine kinase activity
SaSA209_1390	COG0745	RESPONSE REGULATOR receiver
SaSA209_1392	COG0501	Belongs to the peptidase M48B family
SaSA209_1393	COG1704	LemA family
SaSA209_1394	COG0357	Ribosomal RNA small subunit methyltransferase G
SaSA209_1395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SaSA209_1396	COG0569	domain protein
SaSA209_1398	COG1122	ATPase activity
SaSA209_1401	COG1114	Component of the transport system for branched-chain amino acids
SaSA209_1407	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA209_1408	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SaSA209_1410	COG2376	Dihydroxyacetone kinase
SaSA209_1411	COG1309	transcriptional regulator
SaSA209_1412	COG2376	Dihydroxyacetone kinase
SaSA209_1413	COG1461	Dihydroxyacetone kinase
SaSA209_1414	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SaSA209_1415	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA209_1417	COG0789	Transcriptional regulator
SaSA209_1418	COG1323	Belongs to the UPF0348 family
SaSA209_1420	COG2226	methyltransferase
SaSA209_1421	COG0799	negative regulation of ribosome biogenesis
SaSA209_1423	COG1713	HD superfamily hydrolase involved in NAD metabolism
SaSA209_1424	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SaSA209_1425	COG1534	Rna-binding protein
SaSA209_1426	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SaSA209_1427	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SaSA209_1430	COG0154	amidase activity
SaSA209_1431	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SaSA209_1432	COG0574	Belongs to the PEP-utilizing enzyme family
SaSA209_1432	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SaSA209_1434	COG0517	IMP dehydrogenase activity
SaSA209_1436	COG1335	isochorismatase
SaSA209_1437	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SaSA209_1438	COG0436	Aminotransferase
SaSA209_1439	COG0589	response to stress
SaSA209_1441	COG0252	asparaginase activity
SaSA209_1443	COG4989	oxidoreductase activity
SaSA209_1444	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SaSA209_1448	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SaSA209_1450	COG1482	cell wall glycoprotein biosynthetic process
SaSA209_1451	COG1940	carbohydrate kinase activity
SaSA209_1452	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA209_1452	COG2190	(PTS) system
SaSA209_1452	COG1263	PTS System
SaSA209_1453	COG1621	beta-fructofuranosidase activity
SaSA209_1454	COG1609	Transcriptional regulator
SaSA209_1462	COG2131	deaminase
SaSA209_1463	COG0006	proline dipeptidase activity
SaSA209_1470	COG0629	single-stranded DNA binding
SaSA209_1472	COG1194	a g-specific adenine glycosylase
SaSA209_1474	COG3118	belongs to the thioredoxin family
SaSA209_1479	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SaSA209_1480	COG0681	Belongs to the peptidase S26 family
SaSA209_1481	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SaSA209_1484	COG1882	Formate acetyltransferase
SaSA209_1485	COG3576	pyridoxamine 5-phosphate
SaSA209_1486	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SaSA209_1489	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA209_1491	COG2814	Major facilitator Superfamily
SaSA209_1492	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SaSA209_1495	COG0142	geranyltranstransferase activity
SaSA209_1496	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SaSA209_1497	COG4988	ABC transporter
SaSA209_1498	COG1294	oxidase, subunit
SaSA209_1499	COG1271	oxidase subunit
SaSA209_1500	COG1252	NADH dehydrogenase
SaSA209_1505	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SaSA209_1506	COG0789	Transcriptional regulator
SaSA209_1509	COG2081	HI0933 family
SaSA209_1514	COG0456	acetyltransferase
SaSA209_1515	COG1214	PFAM Peptidase M22, glycoprotease
SaSA209_1518	COG3942	CHAP domain
SaSA209_1519	COG0174	glutamine synthetase
SaSA209_1520	COG0789	Transcriptional regulator
SaSA209_1523	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SaSA209_1529	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SaSA209_1531	COG1322	Protein conserved in bacteria
SaSA209_1534	COG1162	GTPase activity
SaSA209_1538	COG0693	protein deglycase activity
SaSA209_1540	COG0084	hydrolase, TatD family'
SaSA209_1545	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SaSA209_1547	COG1696	Membrane protein involved in D-alanine export
SaSA209_1555	COG4175	Glycine betaine
SaSA209_1555	COG3448	diguanylate cyclase activity
SaSA209_1562	COG3775	system Galactitol-specific IIC component
SaSA209_1563	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA209_1565	COG1609	Transcriptional regulator
SaSA209_1566	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SaSA209_1572	COG3037	sugar-specific permease SgaT UlaA
SaSA209_1575	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SaSA209_1578	COG2918	glutathione biosynthetic process
SaSA209_1578	COG1181	Belongs to the D-alanine--D-alanine ligase family
SaSA209_1582	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SaSA209_1583	COG1428	Deoxynucleoside kinase
SaSA209_1585	COG0542	response to heat
SaSA209_1586	COG4463	regulation of RNA biosynthetic process
SaSA209_1589	COG0052	Belongs to the universal ribosomal protein uS2 family
SaSA209_1590	COG0450	alkyl hydroperoxide reductase
SaSA209_1592	COG0025	NhaP-type Na H and K H
SaSA209_1594	COG1619	proteins homologs of microcin C7 resistance protein MccF
SaSA209_1595	COG3590	peptidase
SaSA209_1600	COG1609	Transcriptional regulator
SaSA209_1602	COG3716	PTS system mannose fructose sorbose family IID component
SaSA209_1603	COG3715	PTS system
SaSA209_1604	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA209_1605	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SaSA209_1607	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA209_1616	COG2176	DNA-directed DNA polymerase activity
SaSA209_1617	COG1705	Flagellar rod assembly protein muramidase FlgJ
SaSA209_1617	COG1388	LysM domain
SaSA209_1620	COG4589	Belongs to the CDS family
SaSA209_1621	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SaSA209_1622	COG1862	Preprotein translocase
SaSA209_1626	COG3290	protein histidine kinase activity
SaSA209_1627	COG4565	transcriptional regulatory protein
SaSA209_1628	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SaSA209_1630	COG3842	ATPase activity
SaSA209_1633	COG3684	Belongs to the aldolase LacD family
SaSA209_1634	COG1105	Belongs to the carbohydrate kinase PfkB family
SaSA209_1635	COG0698	ribose 5-phosphate isomerase
SaSA209_1636	COG0698	ribose 5-phosphate isomerase
SaSA209_1644	COG1490	D-aminoacyl-tRNA deacylase activity
SaSA209_1648	COG1363	Peptidase, m42
SaSA209_1652	COG2207	Transcriptional regulator
SaSA209_1652	COG4753	response regulator
SaSA209_1653	COG2972	Histidine kinase
SaSA209_1654	COG3716	PTS system mannose fructose sorbose family IID component
SaSA209_1655	COG3715	PTS system
SaSA209_1660	COG1131	(ABC) transporter
SaSA209_1662	COG2274	protein secretion by the type I secretion system
SaSA209_1663	COG2274	protein secretion by the type I secretion system
SaSA209_1665	COG3290	protein histidine kinase activity
SaSA209_1666	COG3279	Response regulator of the LytR AlgR family
SaSA209_1669	COG2190	(PTS) system
SaSA209_1669	COG1263	PTS System
SaSA209_1669	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA209_1670	COG5002	protein histidine kinase activity
SaSA209_1673	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SaSA209_1674	COG0581	inorganic phosphate transmembrane transporter activity
SaSA209_1676	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SaSA209_1678	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SaSA209_1679	COG2264	protein methyltransferase activity
SaSA209_1681	COG0789	Transcriptional regulator
SaSA209_1688	COG0456	acetyltransferase
SaSA209_1689	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SaSA209_1694	COG1131	(ABC) transporter
SaSA209_1701	COG1131	(ABC) transporter
SaSA209_1703	COG1396	sequence-specific DNA binding
SaSA209_1706	COG2801	Transposase and inactivated derivatives
SaSA209_1708	COG2897	thiosulfate sulfurtransferase activity
SaSA209_1712	COG0371	Dehydrogenase
SaSA209_1714	COG0646	methionine synthase
SaSA209_1714	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SaSA209_1717	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SaSA209_1719	COG0745	RESPONSE REGULATOR receiver
SaSA209_1722	COG0495	leucyl-tRNA aminoacylation
SaSA209_1723	COG2814	Major facilitator Superfamily
SaSA209_1724	COG4667	esterase of the alpha-beta hydrolase superfamily
SaSA209_1728	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaSA209_1729	COG0564	pseudouridine synthase activity
SaSA209_1733	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SaSA209_1734	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
SaSA209_1738	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SaSA209_1739	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SaSA209_1739	COG1116	anion transmembrane transporter activity
SaSA209_1740	COG4120	Belongs to the binding-protein-dependent transport system permease family
SaSA209_1742	COG0561	phosphatase activity
SaSA209_1743	COG2514	catechol 2,3-dioxygenase activity
SaSA209_1744	COG3022	response to hydroperoxide
SaSA209_1745	COG0602	queuosine metabolic process
SaSA209_1749	COG1328	CTP reductase activity
SaSA209_1752	COG3906	Belongs to the UPF0473 family
SaSA209_1755	COG1393	Belongs to the ArsC family
SaSA209_1756	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SaSA209_1757	COG1058	Belongs to the CinA family
SaSA209_1757	COG1546	Belongs to the CinA family
SaSA209_1758	COG2818	Glycosylase
SaSA209_1765	COG0018	arginyl-trna synthetase
SaSA209_1767	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SaSA209_1768	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SaSA209_1770	COG0124	histidyl-tRNA synthetase
SaSA209_1773	COG1288	antiporter activity
SaSA209_1775	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SaSA209_1776	COG3852	Histidine kinase
SaSA209_1777	COG0784	Response regulator, receiver
SaSA209_1778	COG0517	IMP dehydrogenase activity
SaSA209_1778	COG1125	glycine betaine transport
SaSA209_1779	COG1174	glycine betaine transport
SaSA209_1780	COG0392	lysyltransferase activity
SaSA209_1780	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SaSA209_1782	COG3759	membrane
SaSA209_1788	COG0305	Participates in initiation and elongation during chromosome replication
SaSA209_1793	COG0482	sulfurtransferase activity
SaSA209_1794	COG1760	l-serine dehydratase
SaSA209_1795	COG1760	l-serine dehydratase
SaSA209_1796	COG0741	lytic transglycosylase activity
SaSA209_1797	COG1388	LysM domain
SaSA209_1801	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SaSA209_1802	COG0612	Peptidase, M16
SaSA209_1803	COG0612	Peptidase, M16
SaSA209_1804	COG2501	S4 domain
SaSA209_1813	COG2235	arginine
SaSA209_1815	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SaSA209_1817	COG0549	Belongs to the carbamate kinase family
SaSA209_1818	COG0180	Tryptophanyl-tRNA synthetase
SaSA209_1820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SaSA209_1821	COG0488	(ABC) transporter
SaSA209_1822	COG4485	Bacterial membrane protein, YfhO
SaSA209_1824	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SaSA209_1825	COG1475	DNA binding