locus-tag	class	description
SaSA30_0002	COG0592	DNA-directed DNA polymerase activity
SaSA30_0005	COG0012	GTP binding
SaSA30_0006	COG0193	aminoacyl-tRNA hydrolase activity
SaSA30_0007	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SaSA30_0008	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SaSA30_0011	COG0037	tRNA processing
SaSA30_0013	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SaSA30_0023	COG2801	Transposase and inactivated derivatives
SaSA30_0028	COG1695	Transcriptional regulator
SaSA30_0031	COG1755	Isoprenylcysteine carboxyl methyltransferase
SaSA30_0035	COG4224	UPF0291 protein
SaSA30_0038	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA30_0045	COG1131	(ABC) transporter
SaSA30_0047	COG2190	(PTS) system
SaSA30_0047	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA30_0047	COG1263	PTS System
SaSA30_0049	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SaSA30_0050	COG0275	rRNA processing
SaSA30_0052	COG0768	penicillin binding
SaSA30_0054	COG0513	Belongs to the DEAD box helicase family
SaSA30_0057	COG1126	abc transporter atp-binding protein
SaSA30_0059	COG0492	ferredoxin-NADP+ reductase activity
SaSA30_0060	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SaSA30_0063	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaSA30_0065	COG4474	Belongs to the UPF0398 family
SaSA30_0067	COG0116	Belongs to the methyltransferase superfamily
SaSA30_0071	COG1131	(ABC) transporter
SaSA30_0073	COG4585	Histidine kinase
SaSA30_0078	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SaSA30_0080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SaSA30_0080	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SaSA30_0082	COG0515	serine threonine protein kinase
SaSA30_0082	COG2815	serine threonine protein kinase
SaSA30_0084	COG4585	Histidine kinase
SaSA30_0085	COG2197	response regulator
SaSA30_0087	COG1098	S1 RNA binding domain
SaSA30_0089	COG1349	DNA-binding transcription factor activity
SaSA30_0091	COG1447	Phosphotransferase system cellobiose-specific component IIA
SaSA30_0095	COG1739	Uncharacterized protein family UPF0029
SaSA30_0096	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SaSA30_0097	COG1040	competence protein
SaSA30_0099	COG0527	aspartate kinase activity
SaSA30_0101	COG1024	Enoyl-CoA hydratase
SaSA30_0106	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SaSA30_0107	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA30_0108	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SaSA30_0111	COG0439	Biotin carboxylase
SaSA30_0119	COG3716	PTS system mannose fructose sorbose family IID component
SaSA30_0120	COG3715	PTS system
SaSA30_0122	COG0561	phosphatase activity
SaSA30_0125	COG2252	PERMEase
SaSA30_0126	COG0802	atpase or kinase
SaSA30_0130	COG0537	adenosine 5'-monophosphoramidase activity
SaSA30_0132	COG1131	(ABC) transporter
SaSA30_0133	COG4473	ABC transporter
SaSA30_0137	COG0195	Participates in both transcription termination and antitermination
SaSA30_0138	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SaSA30_0146	COG2860	membrane
SaSA30_0148	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaSA30_0148	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SaSA30_0149	COG1832	CoA-binding protein
SaSA30_0155	COG1268	BioY protein
SaSA30_0156	COG1234	tRNA 3'-trailer cleavage
SaSA30_0159	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SaSA30_0160	COG0705	Rhomboid family
SaSA30_0160	COG0457	Tetratricopeptide repeat
SaSA30_0161	COG1744	ABC transporter substrate-binding protein PnrA-like
SaSA30_0162	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SaSA30_0166	COG0706	membrane insertase activity
SaSA30_0169	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SaSA30_0170	COG0436	Aminotransferase
SaSA30_0171	COG1381	Involved in DNA repair and RecF pathway recombination
SaSA30_0172	COG2801	Transposase and inactivated derivatives
SaSA30_0175	COG0416	fatty acid biosynthetic process
SaSA30_0176	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SaSA30_0177	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SaSA30_0178	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SaSA30_0181	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SaSA30_0188	COG1175	transmembrane transport
SaSA30_0190	COG0395	ABC-type sugar transport system, permease component
SaSA30_0193	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SaSA30_0195	COG3458	cephalosporin-C deacetylase activity
SaSA30_0196	COG1737	Transcriptional regulator
SaSA30_0198	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SaSA30_0203	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SaSA30_0206	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SaSA30_0208	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SaSA30_0208	COG2755	lipolytic protein G-D-S-L family
SaSA30_0209	COG1454	alcohol dehydrogenase
SaSA30_0209	COG1012	belongs to the aldehyde dehydrogenase family
SaSA30_0210	COG1064	alcohol dehydrogenase
SaSA30_0212	COG0534	Mate efflux family protein
SaSA30_0235	COG0563	adenylate kinase activity
SaSA30_0237	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SaSA30_0240	COG0202	RNA polymerase activity
SaSA30_0244	COG1121	(ABC) transporter
SaSA30_0245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SaSA30_0247	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SaSA30_0248	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaSA30_0248	COG4499	WXG100 protein secretion system (Wss), protein YukC
SaSA30_0252	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SaSA30_0253	COG1459	type II secretion system
SaSA30_0261	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SaSA30_0262	COG1363	Peptidase, m42
SaSA30_0265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SaSA30_0266	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA30_0269	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SaSA30_0270	COG3275	phosphorelay sensor kinase activity
SaSA30_0271	COG3279	Response regulator of the LytR AlgR family
SaSA30_0273	COG1346	cytolysis
SaSA30_0275	COG0601	transmembrane transport
SaSA30_0276	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA30_0277	COG1122	ATPase activity
SaSA30_0284	COG3959	Transketolase, thiamine diphosphate binding domain
SaSA30_0289	COG1045	serine acetyltransferase
SaSA30_0291	COG0215	cysteine-tRNA ligase activity
SaSA30_0292	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SaSA30_0297	COG1476	TRANSCRIPTIONal
SaSA30_0298	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SaSA30_0308	COG1396	sequence-specific DNA binding
SaSA30_0311	COG1732	Glycine betaine
SaSA30_0321	COG1705	Flagellar rod assembly protein muramidase FlgJ
SaSA30_0326	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SaSA30_0328	COG0351	phosphomethylpyrimidine kinase
SaSA30_0329	COG4720	Psort location CytoplasmicMembrane, score
SaSA30_0330	COG4475	Protein of unknown function (DUF436)
SaSA30_0331	COG0668	transmembrane transport
SaSA30_0336	COG0756	dUTP diphosphatase activity
SaSA30_0339	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SaSA30_0340	COG2801	Transposase and inactivated derivatives
SaSA30_0342	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SaSA30_0343	COG1879	ABC-type sugar transport system periplasmic component
SaSA30_0344	COG1172	Belongs to the binding-protein-dependent transport system permease family
SaSA30_0347	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SaSA30_0348	COG1609	Transcriptional regulator
SaSA30_0349	COG0577	efflux transmembrane transporter activity
SaSA30_0350	COG1136	(ABC) transporter
SaSA30_0352	COG5002	protein histidine kinase activity
SaSA30_0354	COG0165	Argininosuccinate lyase
SaSA30_0355	COG0191	fructose-bisphosphate aldolase activity
SaSA30_0359	COG1461	Dihydroxyacetone kinase
SaSA30_0363	COG1126	abc transporter atp-binding protein
SaSA30_0364	COG0765	amino acid transport
SaSA30_0366	COG1968	undecaprenyl-diphosphatase activity
SaSA30_0367	COG4862	establishment of competence for transformation
SaSA30_0368	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SaSA30_0370	COG0719	Fe-S assembly protein
SaSA30_0371	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SaSA30_0373	COG0719	Fe-S assembly protein
SaSA30_0374	COG1686	Belongs to the peptidase S11 family
SaSA30_0375	COG1686	Belongs to the peptidase S11 family
SaSA30_0376	COG4166	transmembrane transport
SaSA30_0377	COG0601	transmembrane transport
SaSA30_0378	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA30_0379	COG0444	Belongs to the ABC transporter superfamily
SaSA30_0380	COG4608	Belongs to the ABC transporter superfamily
SaSA30_0382	COG2137	regulation of response to DNA damage stimulus
SaSA30_0383	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SaSA30_0385	COG2153	protein acetylation
SaSA30_0387	COG1216	Glycosyl transferase, family 2
SaSA30_0387	COG1442	glycosyl transferase family 8
SaSA30_0397	COG0789	Transcriptional regulator
SaSA30_0398	COG1063	alcohol dehydrogenase
SaSA30_0399	COG0656	L-ascorbic acid biosynthetic process
SaSA30_0406	COG2226	methyltransferase
SaSA30_0408	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaSA30_0409	COG3414	Phosphotransferase system galactitol-specific IIB component
SaSA30_0410	COG3775	system Galactitol-specific IIC component
SaSA30_0413	COG3775	system Galactitol-specific IIC component
SaSA30_0414	COG3414	Phosphotransferase system galactitol-specific IIB component
SaSA30_0415	COG2207	Transcriptional regulator
SaSA30_0418	COG0395	ABC-type sugar transport system, permease component
SaSA30_0422	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SaSA30_0436	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SaSA30_0439	COG2315	Protein conserved in bacteria
SaSA30_0442	COG0742	ribosomal rna small subunit methyltransferase
SaSA30_0445	COG3480	Lon protease (S16) C-terminal proteolytic domain
SaSA30_0447	COG4470	Protein conserved in bacteria
SaSA30_0451	COG1132	(ABC) transporter
SaSA30_0452	COG0512	Glutamine amidotransferase of anthranilate synthase
SaSA30_0453	COG1268	BioY protein
SaSA30_0458	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SaSA30_0470	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SaSA30_0472	COG0762	integral membrane protein
SaSA30_0473	COG2302	S4 RNA-binding domain
SaSA30_0474	COG3599	regulation of cell shape
SaSA30_0478	COG0542	response to heat
SaSA30_0479	COG4703	Protein of unknown function (DUF1797)
SaSA30_0480	COG0765	amino acid transport
SaSA30_0481	COG1126	abc transporter atp-binding protein
SaSA30_0482	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SaSA30_0484	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SaSA30_0485	COG1570	exodeoxyribonuclease VII activity
SaSA30_0488	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SaSA30_0489	COG1438	arginine binding
SaSA30_0490	COG0497	DNA recombination
SaSA30_0491	COG1307	EDD domain protein, DegV family
SaSA30_0501	COG1078	dGTPase activity
SaSA30_0506	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SaSA30_0508	COG2884	Cell division ATP-binding protein ftsE
SaSA30_0509	COG2177	Part of the ABC transporter FtsEX involved in
SaSA30_0514	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SaSA30_0514	COG1199	ATP-dependent helicase activity
SaSA30_0515	COG0436	Aminotransferase
SaSA30_0525	COG0254	rRNA binding
SaSA30_0526	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SaSA30_0527	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SaSA30_0528	COG0716	FMN binding
SaSA30_0529	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SaSA30_0529	COG1605	Chorismate mutase
SaSA30_0532	COG0772	Belongs to the SEDS family
SaSA30_0536	COG0560	Phosphoserine phosphatase
SaSA30_0543	COG1316	TRANSCRIPTIONal
SaSA30_0544	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SaSA30_0546	COG1705	Flagellar rod assembly protein muramidase FlgJ
SaSA30_0546	COG3942	CHAP domain
SaSA30_0570	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SaSA30_0574	COG1131	(ABC) transporter
SaSA30_0587	COG1136	(ABC) transporter
SaSA30_0590	COG0586	Pfam SNARE associated Golgi protein
SaSA30_0591	COG4619	ABC transporter
SaSA30_0592	COG0390	transport system, permease component
SaSA30_0594	COG0583	DNA-binding transcription factor activity
SaSA30_0596	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA30_0598	COG2211	Major facilitator Superfamily
SaSA30_0599	COG3250	beta-galactosidase activity
SaSA30_0600	COG2186	Transcriptional regulator
SaSA30_0603	COG1609	Transcriptional regulator
SaSA30_0606	COG0438	transferase activity, transferring glycosyl groups
SaSA30_0611	COG0765	amino acid transport
SaSA30_0612	COG0765	amino acid transport
SaSA30_0614	COG1126	abc transporter atp-binding protein
SaSA30_0615	COG0745	RESPONSE REGULATOR receiver
SaSA30_0616	COG5002	protein histidine kinase activity
SaSA30_0617	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SaSA30_0618	COG2832	Protein of unknown function (DUF454)
SaSA30_0620	COG1196	nuclear chromosome segregation
SaSA30_0622	COG0552	protein localization to endoplasmic reticulum
SaSA30_0624	COG2801	Transposase and inactivated derivatives
SaSA30_0625	COG3689	TIGRFAM TIGR03943 family protein
SaSA30_0626	COG0701	Predicted permease
SaSA30_0629	COG2183	response to ionizing radiation
SaSA30_0630	COG3091	SprT-like family
SaSA30_0631	COG1983	PspC domain protein
SaSA30_0640	COG4443	Transcriptional Coactivator p15 (PC4)
SaSA30_0642	COG1914	H( )-stimulated, divalent metal cation uptake system
SaSA30_0647	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SaSA30_0650	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SaSA30_0657	COG0772	Belongs to the SEDS family
SaSA30_0661	COG0768	penicillin binding
SaSA30_0664	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SaSA30_0669	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SaSA30_0670	COG2011	ABC-type metal ion transport system permease component
SaSA30_0671	COG1464	Belongs to the NlpA lipoprotein family
SaSA30_0672	COG0513	Belongs to the DEAD box helicase family
SaSA30_0674	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SaSA30_0675	COG0204	Acyl-transferase
SaSA30_0676	COG1555	photosystem II stabilization
SaSA30_0676	COG1596	polysaccharide export
SaSA30_0679	COG1609	Transcriptional regulator
SaSA30_0680	COG0657	acetylesterase activity
SaSA30_0681	COG2264	protein methyltransferase activity
SaSA30_0683	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SaSA30_0684	COG3711	transcriptional antiterminator
SaSA30_0687	COG2801	Transposase and inactivated derivatives
SaSA30_0689	COG3835	regulator
SaSA30_0690	COG1929	Belongs to the glycerate kinase type-1 family
SaSA30_0691	COG2610	gluconate transmembrane transporter activity
SaSA30_0693	COG1846	Transcriptional regulator
SaSA30_0694	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SaSA30_0697	COG0435	Glutathione S-transferase
SaSA30_0698	COG1187	pseudouridine synthase activity
SaSA30_0702	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SaSA30_0706	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SaSA30_0708	COG1442	glycosyl transferase family 8
SaSA30_0713	COG1476	TRANSCRIPTIONal
SaSA30_0716	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SaSA30_0717	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SaSA30_0718	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SaSA30_0721	COG1012	belongs to the aldehyde dehydrogenase family
SaSA30_0722	COG0726	polysaccharide deacetylase
SaSA30_0724	COG2801	Transposase and inactivated derivatives
SaSA30_0725	COG0513	Belongs to the DEAD box helicase family
SaSA30_0727	COG1956	GAF domain-containing protein
SaSA30_0728	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SaSA30_0731	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SaSA30_0738	COG4721	ABC-type cobalt transport system, permease component
SaSA30_0739	COG1122	ATPase activity
SaSA30_0741	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SaSA30_0743	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SaSA30_0744	COG0352	thiamine-phosphate diphosphorylase activity
SaSA30_0745	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SaSA30_0748	COG0024	Methionine aminopeptidase
SaSA30_0751	COG4708	membrane
SaSA30_0752	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SaSA30_0753	COG1597	lipid kinase activity
SaSA30_0754	COG1523	belongs to the glycosyl hydrolase 13 family
SaSA30_0755	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SaSA30_0760	COG0356	it plays a direct role in the translocation of protons across the membrane
SaSA30_0762	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SaSA30_0766	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SaSA30_0768	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SaSA30_0773	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA30_0773	COG0072	phenylalanine-tRNA ligase activity
SaSA30_0774	COG2321	neutral zinc metallopeptidase
SaSA30_0776	COG1074	ATP-dependent DNA helicase activity
SaSA30_0778	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SaSA30_0779	COG0488	(ABC) transporter
SaSA30_0780	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SaSA30_0781	COG0022	dehydrogenase e1 component
SaSA30_0781	COG0508	dehydrogenase complex catalyzes the overall conversion of
SaSA30_0782	COG0508	dehydrogenase complex catalyzes the overall conversion of
SaSA30_0784	COG0095	Lipoate-protein ligase
SaSA30_0785	COG3442	glutamine amidotransferase
SaSA30_0786	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SaSA30_0787	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SaSA30_0792	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SaSA30_0796	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
SaSA30_0797	COG1518	maintenance of DNA repeat elements
SaSA30_0798	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SaSA30_0806	COG1418	mRNA catabolic process
SaSA30_0809	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SaSA30_0812	COG0398	Pfam SNARE associated Golgi protein
SaSA30_0814	COG1131	(ABC) transporter
SaSA30_0815	COG1725	Transcriptional regulator
SaSA30_0818	COG0469	pyruvate kinase activity
SaSA30_0820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SaSA30_0821	COG2824	Alkylphosphonate utilization operon protein PhnA
SaSA30_0822	COG0765	amino acid transport
SaSA30_0823	COG1126	abc transporter atp-binding protein
SaSA30_0826	COG2801	Transposase and inactivated derivatives
SaSA30_0829	COG2813	Specifically methylates the guanine in position
SaSA30_0830	COG0295	cytidine deaminase activity
SaSA30_0837	COG3764	Sortase (surface protein transpeptidase)
SaSA30_0838	COG0346	lactoylglutathione lyase activity
SaSA30_0843	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SaSA30_0845	COG1464	Belongs to the NlpA lipoprotein family
SaSA30_0850	COG0745	RESPONSE REGULATOR receiver
SaSA30_0851	COG5002	protein histidine kinase activity
SaSA30_0856	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SaSA30_0858	COG5002	protein histidine kinase activity
SaSA30_0859	COG0745	RESPONSE REGULATOR receiver
SaSA30_0861	COG0704	Plays a role in the regulation of phosphate uptake
SaSA30_0864	COG0581	inorganic phosphate transmembrane transporter activity
SaSA30_0865	COG0573	inorganic phosphate transmembrane transporter activity
SaSA30_0866	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SaSA30_0868	COG0483	inositol monophosphate 1-phosphatase activity
SaSA30_0869	COG4476	Belongs to the UPF0223 family
SaSA30_0870	COG1393	Belongs to the ArsC family
SaSA30_0871	COG0196	riboflavin kinase activity
SaSA30_0878	COG1136	(ABC) transporter
SaSA30_0879	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SaSA30_0880	COG0758	DNA mediated transformation
SaSA30_0881	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SaSA30_0882	COG4604	ABC transporter, ATP-binding protein
SaSA30_0883	COG4605	iron ion homeostasis
SaSA30_0884	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SaSA30_0885	COG0110	maltose O-acetyltransferase activity
SaSA30_0887	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SaSA30_0888	COG1376	ErfK ybiS ycfS ynhG family protein
SaSA30_0889	COG1966	Carbon starvation protein
SaSA30_0890	COG3279	Response regulator of the LytR AlgR family
SaSA30_0891	COG3275	phosphorelay sensor kinase activity
SaSA30_0900	COG0505	Belongs to the CarA family
SaSA30_0902	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SaSA30_0903	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SaSA30_0906	COG0488	(ABC) transporter
SaSA30_0908	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SaSA30_0911	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SaSA30_0912	COG2801	Transposase and inactivated derivatives
SaSA30_0921	COG0095	Lipoate-protein ligase
SaSA30_0923	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SaSA30_0924	COG4684	Psort location CytoplasmicMembrane, score
SaSA30_0925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SaSA30_0926	COG2801	Transposase and inactivated derivatives
SaSA30_0935	COG2890	protein-(glutamine-N5) methyltransferase activity
SaSA30_0943	COG2233	PERMEase
SaSA30_0951	COG0564	pseudouridine synthase activity
SaSA30_0952	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SaSA30_0953	COG2357	RelA SpoT domain protein
SaSA30_0955	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SaSA30_0956	COG1104	cysteine desulfurase activity
SaSA30_0960	COG0628	permease
SaSA30_0969	COG0561	phosphatase activity
SaSA30_0974	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SaSA30_0976	COG1176	ABC-type spermidine putrescine transport system, permease component I
SaSA30_0983	COG0285	dihydrofolate synthase activity
SaSA30_0984	COG2962	Rard protein
SaSA30_0988	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SaSA30_0996	COG2801	Transposase and inactivated derivatives
SaSA30_1006	COG2261	transglycosylase associated protein
SaSA30_1011	COG1115	amino acid carrier protein
SaSA30_1012	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SaSA30_1014	COG1346	cytolysis
SaSA30_1016	COG0539	negative regulation of cytoplasmic translation
SaSA30_1018	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SaSA30_1020	COG0187	DNA topoisomerase II activity
SaSA30_1021	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SaSA30_1027	COG2089	acid synthase
SaSA30_1034	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SaSA30_1035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SaSA30_1039	COG1316	TRANSCRIPTIONal
SaSA30_1049	COG3842	ATPase activity
SaSA30_1053	COG3527	Alpha-acetolactate decarboxylase
SaSA30_1054	COG0028	Belongs to the TPP enzyme family
SaSA30_1055	COG0457	Tetratricopeptide repeat
SaSA30_1056	COG0628	permease
SaSA30_1059	COG5492	domain, Protein
SaSA30_1060	COG1088	dTDP-glucose 4,6-dehydratase activity
SaSA30_1062	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SaSA30_1063	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SaSA30_1065	COG2384	SAM-dependent methyltransferase
SaSA30_1067	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SaSA30_1070	COG0300	oxidoreductase activity
SaSA30_1074	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SaSA30_1079	COG1573	uracil-dna glycosylase
SaSA30_1080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SaSA30_1082	COG0584	glycerophosphoryl diester phosphodiesterase
SaSA30_1085	COG0534	Mate efflux family protein
SaSA30_1091	COG1136	(ABC) transporter
SaSA30_1097	COG0833	amino acid
SaSA30_1104	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SaSA30_1106	COG3425	synthase
SaSA30_1109	COG1272	protein, Hemolysin III
SaSA30_1118	COG0745	RESPONSE REGULATOR receiver
SaSA30_1119	COG2357	RelA SpoT domain protein
SaSA30_1120	COG1132	(ABC) transporter
SaSA30_1122	COG1132	(ABC) transporter
SaSA30_1123	COG1132	(ABC) transporter
SaSA30_1125	COG0488	(ABC) transporter
SaSA30_1126	COG0617	tRNA 3'-terminal CCA addition
SaSA30_1131	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SaSA30_1131	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaSA30_1131	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SaSA30_1132	COG1105	Belongs to the carbohydrate kinase PfkB family
SaSA30_1133	COG1349	DNA-binding transcription factor activity
SaSA30_1140	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SaSA30_1142	COG1837	Belongs to the UPF0109 family
SaSA30_1144	COG0577	efflux transmembrane transporter activity
SaSA30_1145	COG1136	(ABC) transporter
SaSA30_1146	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SaSA30_1148	COG0505	Belongs to the CarA family
SaSA30_1150	COG0564	pseudouridine synthase activity
SaSA30_1152	COG0583	DNA-binding transcription factor activity
SaSA30_1153	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SaSA30_1157	COG0301	tRNA thio-modification
SaSA30_1158	COG1104	cysteine desulfurase activity
SaSA30_1165	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SaSA30_1166	COG1368	sulfuric ester hydrolase activity
SaSA30_1175	COG2244	polysaccharide biosynthetic process
SaSA30_1176	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SaSA30_1177	COG1120	ATPase activity
SaSA30_1181	COG2801	Transposase and inactivated derivatives
SaSA30_1185	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SaSA30_1186	COG1253	flavin adenine dinucleotide binding
SaSA30_1187	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SaSA30_1188	COG1242	4 iron, 4 sulfur cluster binding
SaSA30_1189	COG0671	phosphoesterase, PA-phosphatase related
SaSA30_1190	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SaSA30_1198	COG0297	glycogen (starch) synthase activity
SaSA30_1206	COG3475	LICD family
SaSA30_1209	COG0463	Glycosyl transferase, family 2
SaSA30_1210	COG1215	transferase activity, transferring glycosyl groups
SaSA30_1212	COG1091	dTDP-4-dehydrorhamnose reductase activity
SaSA30_1213	COG2151	metal-sulfur cluster biosynthetic enzyme
SaSA30_1214	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SaSA30_1215	COG0358	DNA primase activity
SaSA30_1216	COG1970	mechanosensitive ion channel activity
SaSA30_1219	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA30_1220	COG0004	ammonium transporteR
SaSA30_1224	COG2271	Major facilitator Superfamily
SaSA30_1225	COG0058	SHG alpha-glucan phosphorylase activity
SaSA30_1226	COG1640	4-alpha-glucanotransferase
SaSA30_1227	COG1609	Transcriptional regulator
SaSA30_1229	COG1175	transmembrane transport
SaSA30_1230	COG3833	ABC-type maltose transport systems, permease component
SaSA30_1232	COG2801	Transposase and inactivated derivatives
SaSA30_1238	COG0438	transferase activity, transferring glycosyl groups
SaSA30_1249	COG0765	amino acid transport
SaSA30_1250	COG1126	abc transporter atp-binding protein
SaSA30_1255	COG2309	aminopeptidase activity
SaSA30_1258	COG1187	pseudouridine synthase activity
SaSA30_1259	COG0656	L-ascorbic acid biosynthetic process
SaSA30_1260	COG0778	Nitroreductase
SaSA30_1261	COG0346	lactoylglutathione lyase activity
SaSA30_1262	COG0463	Glycosyl transferase, family 2
SaSA30_1263	COG1113	amino acid transport
SaSA30_1265	COG0557	exoribonuclease II activity
SaSA30_1267	COG2814	Major facilitator Superfamily
SaSA30_1269	COG1131	(ABC) transporter
SaSA30_1285	COG1702	phosphate starvation-inducible protein PhoH
SaSA30_1293	COG0444	Belongs to the ABC transporter superfamily
SaSA30_1294	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SaSA30_1295	COG0601	transmembrane transport
SaSA30_1296	COG0747	negative chemotaxis
SaSA30_1298	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SaSA30_1300	COG1473	amidohydrolase
SaSA30_1301	COG0583	DNA-binding transcription factor activity
SaSA30_1304	COG1674	ftsk spoiiie
SaSA30_1305	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SaSA30_1311	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SaSA30_1316	COG0673	inositol 2-dehydrogenase activity
SaSA30_1319	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA30_1323	COG1215	transferase activity, transferring glycosyl groups
SaSA30_1330	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA30_1330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SaSA30_1333	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SaSA30_1335	COG0708	Exodeoxyribonuclease III
SaSA30_1336	COG1393	Belongs to the ArsC family
SaSA30_1337	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SaSA30_1338	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA30_1340	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SaSA30_1344	COG0470	DNA polymerase III
SaSA30_1346	COG0517	IMP dehydrogenase activity
SaSA30_1347	COG0410	ABC transporter
SaSA30_1348	COG0411	ABC transporter
SaSA30_1350	COG0559	Belongs to the binding-protein-dependent transport system permease family
SaSA30_1355	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SaSA30_1357	COG0531	amino acid
SaSA30_1361	COG2801	Transposase and inactivated derivatives
SaSA30_1363	COG1187	pseudouridine synthase activity
SaSA30_1369	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SaSA30_1370	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SaSA30_1373	COG1827	regulation of RNA biosynthetic process
SaSA30_1376	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SaSA30_1377	COG1254	Belongs to the acylphosphatase family
SaSA30_1379	COG0765	amino acid transport
SaSA30_1380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA30_1383	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SaSA30_1387	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SaSA30_1389	COG1484	DNA-dependent DNA replication
SaSA30_1392	COG5002	protein histidine kinase activity
SaSA30_1393	COG0745	RESPONSE REGULATOR receiver
SaSA30_1395	COG0501	Belongs to the peptidase M48B family
SaSA30_1396	COG1704	LemA family
SaSA30_1397	COG0357	Ribosomal RNA small subunit methyltransferase G
SaSA30_1398	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SaSA30_1399	COG0569	domain protein
SaSA30_1404	COG1114	Component of the transport system for branched-chain amino acids
SaSA30_1410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SaSA30_1411	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SaSA30_1413	COG2376	Dihydroxyacetone kinase
SaSA30_1414	COG1309	transcriptional regulator
SaSA30_1415	COG2376	Dihydroxyacetone kinase
SaSA30_1416	COG1461	Dihydroxyacetone kinase
SaSA30_1417	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SaSA30_1418	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA30_1421	COG0789	Transcriptional regulator
SaSA30_1422	COG1323	Belongs to the UPF0348 family
SaSA30_1424	COG2226	methyltransferase
SaSA30_1425	COG0799	negative regulation of ribosome biogenesis
SaSA30_1427	COG1713	HD superfamily hydrolase involved in NAD metabolism
SaSA30_1428	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SaSA30_1429	COG1534	Rna-binding protein
SaSA30_1430	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SaSA30_1431	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SaSA30_1434	COG0154	amidase activity
SaSA30_1435	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SaSA30_1436	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SaSA30_1436	COG0574	Belongs to the PEP-utilizing enzyme family
SaSA30_1438	COG0517	IMP dehydrogenase activity
SaSA30_1440	COG1335	isochorismatase
SaSA30_1441	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SaSA30_1442	COG0436	Aminotransferase
SaSA30_1443	COG0589	response to stress
SaSA30_1445	COG0252	asparaginase activity
SaSA30_1447	COG4989	oxidoreductase activity
SaSA30_1448	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SaSA30_1452	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SaSA30_1454	COG1482	cell wall glycoprotein biosynthetic process
SaSA30_1455	COG1940	carbohydrate kinase activity
SaSA30_1456	COG1263	PTS System
SaSA30_1456	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA30_1456	COG2190	(PTS) system
SaSA30_1457	COG1621	beta-fructofuranosidase activity
SaSA30_1458	COG1609	Transcriptional regulator
SaSA30_1466	COG2131	deaminase
SaSA30_1467	COG0006	proline dipeptidase activity
SaSA30_1474	COG0629	single-stranded DNA binding
SaSA30_1476	COG1194	a g-specific adenine glycosylase
SaSA30_1478	COG3118	belongs to the thioredoxin family
SaSA30_1483	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SaSA30_1484	COG0681	Belongs to the peptidase S26 family
SaSA30_1485	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SaSA30_1488	COG1882	Formate acetyltransferase
SaSA30_1489	COG3576	pyridoxamine 5-phosphate
SaSA30_1490	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SaSA30_1493	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SaSA30_1495	COG2814	Major facilitator Superfamily
SaSA30_1496	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SaSA30_1499	COG0142	geranyltranstransferase activity
SaSA30_1500	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SaSA30_1501	COG4988	ABC transporter
SaSA30_1502	COG1294	oxidase, subunit
SaSA30_1503	COG1271	oxidase subunit
SaSA30_1504	COG1252	NADH dehydrogenase
SaSA30_1509	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SaSA30_1510	COG0789	Transcriptional regulator
SaSA30_1513	COG2081	HI0933 family
SaSA30_1514	COG2081	HI0933 family
SaSA30_1520	COG1214	PFAM Peptidase M22, glycoprotease
SaSA30_1523	COG3942	CHAP domain
SaSA30_1524	COG0174	glutamine synthetase
SaSA30_1525	COG0789	Transcriptional regulator
SaSA30_1528	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SaSA30_1534	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SaSA30_1536	COG1322	Protein conserved in bacteria
SaSA30_1539	COG1162	GTPase activity
SaSA30_1543	COG0693	protein deglycase activity
SaSA30_1551	COG1696	Membrane protein involved in D-alanine export
SaSA30_1559	COG3448	diguanylate cyclase activity
SaSA30_1559	COG4175	Glycine betaine
SaSA30_1566	COG3775	system Galactitol-specific IIC component
SaSA30_1567	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SaSA30_1569	COG1609	Transcriptional regulator
SaSA30_1570	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SaSA30_1576	COG3037	sugar-specific permease SgaT UlaA
SaSA30_1579	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SaSA30_1582	COG2918	glutathione biosynthetic process
SaSA30_1582	COG1181	Belongs to the D-alanine--D-alanine ligase family
SaSA30_1586	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SaSA30_1587	COG1428	Deoxynucleoside kinase
SaSA30_1589	COG0542	response to heat
SaSA30_1590	COG4463	regulation of RNA biosynthetic process
SaSA30_1593	COG0052	Belongs to the universal ribosomal protein uS2 family
SaSA30_1594	COG0450	alkyl hydroperoxide reductase
SaSA30_1596	COG0025	NhaP-type Na H and K H
SaSA30_1598	COG1619	proteins homologs of microcin C7 resistance protein MccF
SaSA30_1599	COG3590	peptidase
SaSA30_1604	COG1609	Transcriptional regulator
SaSA30_1606	COG3716	PTS system mannose fructose sorbose family IID component
SaSA30_1607	COG3715	PTS system
SaSA30_1608	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA30_1609	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SaSA30_1611	COG1028	Short-chain dehydrogenase reductase Sdr
SaSA30_1618	COG2176	DNA-directed DNA polymerase activity
SaSA30_1619	COG1705	Flagellar rod assembly protein muramidase FlgJ
SaSA30_1619	COG1388	LysM domain
SaSA30_1622	COG4589	Belongs to the CDS family
SaSA30_1624	COG1862	Preprotein translocase
SaSA30_1629	COG4565	transcriptional regulatory protein
SaSA30_1630	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SaSA30_1632	COG3842	ATPase activity
SaSA30_1635	COG3684	Belongs to the aldolase LacD family
SaSA30_1636	COG1105	Belongs to the carbohydrate kinase PfkB family
SaSA30_1637	COG0698	ribose 5-phosphate isomerase
SaSA30_1638	COG0698	ribose 5-phosphate isomerase
SaSA30_1646	COG1490	D-aminoacyl-tRNA deacylase activity
SaSA30_1650	COG1363	Peptidase, m42
SaSA30_1655	COG2972	Histidine kinase
SaSA30_1656	COG3716	PTS system mannose fructose sorbose family IID component
SaSA30_1657	COG3715	PTS system
SaSA30_1662	COG1131	(ABC) transporter
SaSA30_1664	COG2274	protein secretion by the type I secretion system
SaSA30_1665	COG2274	protein secretion by the type I secretion system
SaSA30_1667	COG3290	protein histidine kinase activity
SaSA30_1668	COG3279	Response regulator of the LytR AlgR family
SaSA30_1671	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SaSA30_1671	COG1263	PTS System
SaSA30_1671	COG2190	(PTS) system
SaSA30_1672	COG5002	protein histidine kinase activity
SaSA30_1675	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SaSA30_1676	COG0581	inorganic phosphate transmembrane transporter activity
SaSA30_1678	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SaSA30_1680	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SaSA30_1681	COG2264	protein methyltransferase activity
SaSA30_1683	COG0789	Transcriptional regulator
SaSA30_1690	COG0456	acetyltransferase
SaSA30_1691	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SaSA30_1705	COG1396	sequence-specific DNA binding
SaSA30_1708	COG2801	Transposase and inactivated derivatives
SaSA30_1710	COG2897	thiosulfate sulfurtransferase activity
SaSA30_1714	COG0371	Dehydrogenase
SaSA30_1716	COG0646	methionine synthase
SaSA30_1716	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SaSA30_1719	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SaSA30_1724	COG0495	leucyl-tRNA aminoacylation
SaSA30_1725	COG2814	Major facilitator Superfamily
SaSA30_1726	COG4667	esterase of the alpha-beta hydrolase superfamily
SaSA30_1730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SaSA30_1731	COG0564	pseudouridine synthase activity
SaSA30_1735	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SaSA30_1736	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
SaSA30_1740	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SaSA30_1741	COG1116	anion transmembrane transporter activity
SaSA30_1741	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SaSA30_1742	COG4120	Belongs to the binding-protein-dependent transport system permease family
SaSA30_1744	COG0561	phosphatase activity
SaSA30_1745	COG2514	catechol 2,3-dioxygenase activity
SaSA30_1746	COG3022	response to hydroperoxide
SaSA30_1747	COG0602	queuosine metabolic process
SaSA30_1751	COG1328	CTP reductase activity
SaSA30_1754	COG3906	Belongs to the UPF0473 family
SaSA30_1757	COG1393	Belongs to the ArsC family
SaSA30_1758	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SaSA30_1759	COG1058	Belongs to the CinA family
SaSA30_1759	COG1546	Belongs to the CinA family
SaSA30_1760	COG2818	Glycosylase
SaSA30_1767	COG0018	arginyl-trna synthetase
SaSA30_1769	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SaSA30_1770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SaSA30_1772	COG0124	histidyl-tRNA synthetase
SaSA30_1775	COG1288	antiporter activity
SaSA30_1777	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SaSA30_1779	COG0784	Response regulator, receiver
SaSA30_1780	COG1125	glycine betaine transport
SaSA30_1780	COG0517	IMP dehydrogenase activity
SaSA30_1781	COG1174	glycine betaine transport
SaSA30_1782	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SaSA30_1782	COG0392	lysyltransferase activity
SaSA30_1784	COG3759	membrane
SaSA30_1790	COG0305	Participates in initiation and elongation during chromosome replication
SaSA30_1795	COG0482	sulfurtransferase activity
SaSA30_1796	COG1760	l-serine dehydratase
SaSA30_1797	COG1760	l-serine dehydratase
SaSA30_1798	COG0741	lytic transglycosylase activity
SaSA30_1799	COG1388	LysM domain
SaSA30_1803	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SaSA30_1805	COG0612	Peptidase, M16
SaSA30_1806	COG2501	S4 domain
SaSA30_1815	COG2235	arginine
SaSA30_1817	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SaSA30_1819	COG0549	Belongs to the carbamate kinase family
SaSA30_1820	COG0180	Tryptophanyl-tRNA synthetase
SaSA30_1823	COG0488	(ABC) transporter
SaSA30_1824	COG4485	Bacterial membrane protein, YfhO
SaSA30_1827	COG1475	DNA binding