locus-tag	class	description
SanJ4211_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
SanJ4211_0005	ENOG4105C3G	gtp-binding protein
SanJ4211_0006	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
SanJ4211_0007	ENOG4108JA2	transcriptioN-repair coupling factor
SanJ4211_0008	ENOG41082I2	s4 domain protein
SanJ4211_0012	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
SanJ4211_0013	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
SanJ4211_0014	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
SanJ4211_0016	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
SanJ4211_0018	ENOG41068JE	domain protein
SanJ4211_0019	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
SanJ4211_0020	ENOG4105CHM	Aminotransferase
SanJ4211_0021	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
SanJ4211_0023	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
SanJ4211_0024	ENOG4105C8V	SAICAR synthetase
SanJ4211_0026	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
SanJ4211_0027	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
SanJ4211_0028	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
SanJ4211_0030c	ENOG41068JE	domain protein
SanJ4211_0032	ENOG4105C12	Phosphoribosylglycinamide synthetase
SanJ4211_0035	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
SanJ4211_0036	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
SanJ4211_0040	ENOG4105C83	adenylosuccinate lyase
SanJ4211_0041c	ENOG4105CMT	Dihydroxyacetone kinase
SanJ4211_0043	ENOG4105CMT	Dihydroxyacetone kinase
SanJ4211_0044	ENOG4108UTZ	Dihydroxyacetone kinase
SanJ4211_0045	ENOG4105VDH	Dihydroxyacetone kinase
SanJ4211_0046	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
SanJ4211_0048c	ENOG4105FDP	GntR family transcriptional regulator
SanJ4211_0050	ENOG4108IQ3	PTS system
SanJ4211_0051	ENOG4105ETZ	PTS System
SanJ4211_0052	ENOG4105F3R	pts system mannose fructose sorbose family iid
SanJ4211_0054	ENOG4105E70	isomerase
SanJ4211_0055	ENOG4105D2M	Aldolase
SanJ4211_0056	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
SanJ4211_0057	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
SanJ4211_0059	ENOG4105KJF	protein tyrosine phosphatase
SanJ4211_0062	ENOG4108EKI	Dehydrogenase
SanJ4211_0063	ENOG4105C0A	alcohol dehydrogenase
SanJ4211_0064	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
SanJ4211_0066	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
SanJ4211_0067	ENOG4105DRS	transport system, permease
SanJ4211_0080	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
SanJ4211_0081	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
SanJ4211_0082	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
SanJ4211_0086	ENOG4105MKU	Transcriptional regulator
SanJ4211_0087	ENOG4107QID	Threonine synthase
SanJ4211_0089	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
SanJ4211_0091	ENOG4105KA3	membrAne
SanJ4211_0092	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
SanJ4211_0097	ENOG41067TZ	transcriptional regulator, MarR family
SanJ4211_0098	ENOG4105FDK	ABC transporter
SanJ4211_0100	ENOG4105DSE	periplasmic solute binding protein
SanJ4211_0101	ENOG4105NA0	Transcriptional regulator
SanJ4211_0102	ENOG4105C59	p-type ATPase
SanJ4211_0104c	ENOG4108YBP	pseudouridine synthase
SanJ4211_0105	ENOG4105BZ4	penicillin-binding protein
SanJ4211_0107	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
SanJ4211_0108c	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SanJ4211_0122	ENOG4105CDU	Replicative dna helicase
SanJ4211_0124	ENOG4106CVF	DNA replication protein
SanJ4211_0171c	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
SanJ4211_0177	ENOG4107TXC	Transcriptional regulator
SanJ4211_0178c	ENOG4105CBX	hi0933 family
SanJ4211_0180	ENOG4107DB1	DUF218 domain
SanJ4211_0181	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
SanJ4211_0182c	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
SanJ4211_0183c	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
SanJ4211_0184	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
SanJ4211_0187	ENOG4107S1E	Beta-lactamase
SanJ4211_0188	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
SanJ4211_0191	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
SanJ4211_0193c	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
SanJ4211_0196c	ENOG4105C6N	Formate acetyltransferase
SanJ4211_0198	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
SanJ4211_0201	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
SanJ4211_0203	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
SanJ4211_0204	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
SanJ4211_0205	ENOG4105CH2	amidohydrolase
SanJ4211_0206	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
SanJ4211_0208c	ENOG4105DHI	Methyltransferase
SanJ4211_0209c	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
SanJ4211_0211	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
SanJ4211_0212	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
SanJ4211_0213	ENOG4105BZA	Phosphoglycerate kinase
SanJ4211_0215	ENOG4105KV4	Transcriptional regulator
SanJ4211_0216	ENOG4105C5F	glutamine synthetase
SanJ4211_0226	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
SanJ4211_0227	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
SanJ4211_0230	ENOG4105CV1	Transketolase (EC 2.2.1.1)
SanJ4211_0231	ENOG4108ZQX	ybak prolyl-trna synthetase
SanJ4211_0241c	ENOG4105K4H	Nlp p60 protein
SanJ4211_0247c	ENOG4106128	DNA-binding helix-turn-helix protein
SanJ4211_0248c	ENOG4106BHR	ftsk SpoIIIE family protein
SanJ4211_0250c	ENOG4108RYM	conjugative transposon protein
SanJ4211_0251	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
SanJ4211_0252	ENOG4105KNE	Phosphatidate cytidylyltransferase
SanJ4211_0253	ENOG4105DZP	Membrane-associated zinc metalloprotease
SanJ4211_0254	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
SanJ4211_0256	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
SanJ4211_0258c	ENOG4105CN9	Peptidase m42 family protein
SanJ4211_0261	ENOG4108VDD	TRNA binding domain protein
SanJ4211_0264	ENOG4105BZU	Histidine kinase
SanJ4211_0265	ENOG4105WH1	Two component transcriptional regulator luxr family
SanJ4211_0269	ENOG4105ETZ	PTS System
SanJ4211_0270	ENOG4105F3R	pts system mannose fructose sorbose family iid
SanJ4211_0272	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
SanJ4211_0273	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
SanJ4211_0275	ENOG4105WPN	DNA integration recombination invertion protein
SanJ4211_0276	ENOG4105ZMH	deoxynucleoside kinase
SanJ4211_0280c	ENOG4105D1H	recombination factor protein RarA
SanJ4211_0284	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
SanJ4211_0285	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
SanJ4211_0288	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
SanJ4211_0290c	ENOG4105DSE	periplasmic solute binding protein
SanJ4211_0291c	ENOG4105CC5	ABC transporter
SanJ4211_0292c	ENOG4105DIK	(ABC) transporter
SanJ4211_0293	ENOG4105C9K	Endothelin-converting enzyme 1
SanJ4211_0294	ENOG4108JJ9	ABC, transporter
SanJ4211_0295	ENOG4105BZ1	(ABC) transporter
SanJ4211_0297c	ENOG4105CFH	Aspartokinase
SanJ4211_0298	ENOG4105CGU	Enoyl-CoA hydratase
SanJ4211_0300	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
SanJ4211_0301	ENOG410854A	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
SanJ4211_0302	ENOG4105EA8	2-Nitropropane dioxygenase
SanJ4211_0303	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
SanJ4211_0304	ENOG4105CHR	reductase
SanJ4211_0305	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
SanJ4211_0307	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
SanJ4211_0308	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
SanJ4211_0309	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
SanJ4211_0310	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
SanJ4211_0311	ENOG4105DQR	SNARE associated Golgi
SanJ4211_0312c	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
SanJ4211_0314c	ENOG4105F3R	pts system mannose fructose sorbose family iid
SanJ4211_0315c	ENOG4105ETZ	PTS System
SanJ4211_0317c	ENOG4108KP7	hydrolase
SanJ4211_0319	ENOG4105C7N	Xanthine uracil vitamin C permease
SanJ4211_0320	ENOG4105K8N	protein family UPF0079, ATPase
SanJ4211_0322	ENOG4108KGH	TRANSCRIPTIONal
SanJ4211_0324c	ENOG4105K59	histidine triad (HIT) protein
SanJ4211_0327	ENOG4108V15	phosphotransferase enzyme family
SanJ4211_0328	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
SanJ4211_0330	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
SanJ4211_0331	ENOG4105CHV	Transcription elongation factor NusA
SanJ4211_0332	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
SanJ4211_0335	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
SanJ4211_0338	ENOG4105CE4	GlcNAc 6-P deacetylase
SanJ4211_0344	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
SanJ4211_0345	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
SanJ4211_0346	ENOG4105VPS	UPF0291 protein
SanJ4211_0348c	ENOG4105CZN	Potassium uptake protein
SanJ4211_0351	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
SanJ4211_0353	ENOG4105CJN	penicillin-binding protein
SanJ4211_0354	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
SanJ4211_0355	ENOG4105DIB	Oligopeptide-binding protein
SanJ4211_0356	ENOG4105D2N	Aldolase
SanJ4211_0360	ENOG4105VB9	50S ribosomal protein l28
SanJ4211_0362	ENOG4105DP4	dak2 domain fusion protein ylov
SanJ4211_0364	ENOG4108M15	ABC transporter
SanJ4211_0365	ENOG4105KCT	ABC transporter
SanJ4211_0366	ENOG4105BZU	Histidine kinase
SanJ4211_0370c	ENOG4105CDA	abc transporter atp-binding protein
SanJ4211_0371c	ENOG4105E5Q	amino acid AbC transporter
SanJ4211_0373	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
SanJ4211_0375	ENOG41084EC	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
SanJ4211_0376	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
SanJ4211_0377	ENOG4105ESV	Glycosyl transferase, family 4
SanJ4211_0379	ENOG4105JRK	feS assembly protein SufD
SanJ4211_0380	ENOG4105C9B	Cysteine desulfurase
SanJ4211_0381	ENOG4108UNV	SUF system FeS assembly protein, NifU family
SanJ4211_0383	ENOG4105C1J	atp-dependent rna helicase
SanJ4211_0384	ENOG4105E5Q	amino acid AbC transporter
SanJ4211_0385	ENOG4105CDA	abc transporter atp-binding protein
SanJ4211_0388	ENOG4105C3M	thioredoxin reductase
SanJ4211_0389	ENOG4105C85	amino acid
SanJ4211_0390	ENOG4105DAP	Nicotinate phosphoribosyltransferase
SanJ4211_0391	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
SanJ4211_0392	ENOG4105CTZ	aminopeptidase c
SanJ4211_0393c	ENOG4105BZ4	penicillin-binding protein
SanJ4211_0394c	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
SanJ4211_0395	ENOG4108UKS	UPF0398 protein
SanJ4211_0396	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
SanJ4211_0397	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
SanJ4211_0398	ENOG41070VT	
SanJ4211_0399	ENOG4105D3R	alkyl hydroperoxide reductase
SanJ4211_0400	ENOG4108JU3	Alkyl hydroperoxide reductase
SanJ4211_0401c	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
SanJ4211_0402	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
SanJ4211_0403	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
SanJ4211_0404	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
SanJ4211_0405	ENOG4105C25	Primosomal protein n'
SanJ4211_0406	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
SanJ4211_0407	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
SanJ4211_0408	ENOG4108ZF3	Phosphatase
SanJ4211_0409	ENOG4105D9P	serine threonine protein kinase
SanJ4211_0414	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
SanJ4211_0416c	ENOG4105EVI	UPF0374 protein
SanJ4211_0417c	ENOG410902V	Modulates RecA activity (By similarity)
SanJ4211_0419	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
SanJ4211_0421c	ENOG4105EA8	2-Nitropropane dioxygenase
SanJ4211_0425	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
SanJ4211_0427	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
SanJ4211_0429c	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
SanJ4211_0431	ENOG4105MJ2	Competence protein
SanJ4211_0433	ENOG4106H78	methyltransferase
SanJ4211_0434	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
SanJ4211_0435	ENOG41063PX	domain protein
SanJ4211_0436	ENOG4105MMD	transcriptional regulator
SanJ4211_0437	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
SanJ4211_0439	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
SanJ4211_0440c	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
SanJ4211_0445	ENOG4105CI3	gtp-binding protein typa
SanJ4211_0447	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
SanJ4211_0448	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
SanJ4211_0449	ENOG4105U2C	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
SanJ4211_0451	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
SanJ4211_0452	ENOG4105DFA	alanine racemase domain protein
SanJ4211_0453	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
SanJ4211_0456	ENOG4105MMF	Cell division protein DIVIVA
SanJ4211_0457	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
SanJ4211_0458c	ENOG4108U05	Transcriptional regulator
SanJ4211_0461	ENOG4105C02	permease
SanJ4211_0464c	ENOG4107414	GntR family transcriptional regulator
SanJ4211_0465	ENOG4105C5Y	PTS System
SanJ4211_0466	ENOG4105C5Y	PTS System
SanJ4211_0467	ENOG4105C5Y	PTS System
SanJ4211_0468	ENOG4105CG3	alpha amylase, catalytic region
SanJ4211_0470	ENOG4105F1A	Pyruvate formate-lyase
SanJ4211_0471	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
SanJ4211_0475c	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
SanJ4211_0477	ENOG4105C28	cystathionine
SanJ4211_0478	ENOG4105C87	Aminotransferase class I and II
SanJ4211_0479	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
SanJ4211_0480	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
SanJ4211_0481	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
SanJ4211_0482	ENOG4105WUC	UPF0298 protein
SanJ4211_0483	ENOG4105CP9	extracellular ligand-binding receptor
SanJ4211_0485	ENOG4105C32	Amino acid ABC transporter (Permease)
SanJ4211_0486	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
SanJ4211_0487	ENOG4105C0Z	ABC transporter
SanJ4211_0488	ENOG4108IV0	ABC, transporter
SanJ4211_0489	ENOG41080XP	Cbs domain
SanJ4211_0490c	ENOG4108JYZ	YitT family
SanJ4211_0491	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
SanJ4211_0492	ENOG4105FA2	dna polymerase iii
SanJ4211_0493	ENOG41063V3	Involved in initiation control of chromosome replication (By similarity)
SanJ4211_0494	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
SanJ4211_0495	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
SanJ4211_0496	ENOG41080E8	Transcriptional regulator, Spx MgsR family
SanJ4211_0497	ENOG4105CSM	endonuclease III
SanJ4211_0498c	ENOG4105CGK	Exodeoxyribonuclease III
SanJ4211_0499	ENOG41082BM	Transcriptional regulator, arsr family
SanJ4211_0504	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
SanJ4211_0506	ENOG4105CJZ	response regulator
SanJ4211_0507	ENOG4105EWM	Histidine kinase
SanJ4211_0510	ENOG4105C19	ABC transporter
SanJ4211_0516	ENOG4105C19	ABC transporter
SanJ4211_0517	ENOG4108HVR	ABC transporter, permease
SanJ4211_0518	ENOG4105CUB	amino acid
SanJ4211_0519	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
SanJ4211_0522c	ENOG4105VEQ	Cold shock protein
SanJ4211_0525	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
SanJ4211_0528	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
SanJ4211_0531	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
SanJ4211_0533	ENOG4105C5H	ABC transporter
SanJ4211_0534c	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
SanJ4211_0536	ENOG4105FM1	phage shock protein C
SanJ4211_0537	ENOG4105CNU	cell division protein FtsK
SanJ4211_0538	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
SanJ4211_0541	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
SanJ4211_0542	ENOG4108I0Z	Aconitate hydratase
SanJ4211_0543	ENOG4105BZN	citrate synthase
SanJ4211_0544	ENOG4108HMX	isocitrate dehydrogenase (NADP)
SanJ4211_0545	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
SanJ4211_0546	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
SanJ4211_0547	ENOG4105QNR	S1 RNA binding domain protein
SanJ4211_0549	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
SanJ4211_0551	ENOG4108JJA	ABC, transporter
SanJ4211_0552	ENOG4107VK6	Transport protein ComB
SanJ4211_0554c	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
SanJ4211_0566	ENOG4105DBV	ornithine carbamoyltransferase
SanJ4211_0567	ENOG4105C5B	carbamate kinase
SanJ4211_0568	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
SanJ4211_0569	ENOG4107QSE	Dipeptidase
SanJ4211_0570c	ENOG4105DQ6	Transposase
SanJ4211_0572c	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
SanJ4211_0573c	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
SanJ4211_0574	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
SanJ4211_0578	ENOG4105CS2	ec 3.2.1.21
SanJ4211_0580	ENOG4105W3H	MtN3 and saliva related transmembrane protein
SanJ4211_0582	ENOG4105EMD	TRANSCRIPTIONal
SanJ4211_0583	ENOG4105VCP	PTS System
SanJ4211_0585	ENOG4105CK1	PTS System
SanJ4211_0588	ENOG4108VQJ	O-methyltransferase
SanJ4211_0589	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
SanJ4211_0591	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
SanJ4211_0593	ENOG4105DQX	Zinc finger domain
SanJ4211_0596c	ENOG4108RMH	femAB family
SanJ4211_0597c	ENOG4108TV1	Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity)
SanJ4211_0599c	ENOG4105DCI	Phosphohydrolase
SanJ4211_0607	ENOG4108HCJ	Hydrolase
SanJ4211_0608	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
SanJ4211_0609	ENOG4105CAK	Cell division ATP-binding protein ftsE
SanJ4211_0610	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
SanJ4211_0612	ENOG4105DVT	helicase
SanJ4211_0613	ENOG4105HMI	Membrane
SanJ4211_0617	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
SanJ4211_0618	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
SanJ4211_0622c	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
SanJ4211_0623	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SanJ4211_0624	ENOG4105BZU	Histidine kinase
SanJ4211_0628	ENOG4107FQX	Alpha-acetolactate decarboxylase
SanJ4211_0629c	ENOG4105F23	Fibronectin-binding protein
SanJ4211_0632	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
SanJ4211_0634	ENOG4105VEM	Conserved domain protein
SanJ4211_0635	ENOG4108IUX	(ABC) transporter
SanJ4211_0636	ENOG4105RHA	ABC transporter, permease
SanJ4211_0637	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
SanJ4211_0638	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
SanJ4211_0639	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
SanJ4211_0640	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
SanJ4211_0641	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
SanJ4211_0642	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
SanJ4211_0644	ENOG4105ZA1	atp synthase
SanJ4211_0645	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
SanJ4211_0646	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
SanJ4211_0647	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
SanJ4211_0648	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
SanJ4211_0649	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
SanJ4211_0651	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
SanJ4211_0653	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
SanJ4211_0655	ENOG4105ZT7	DNA-entry nuclease
SanJ4211_0657	ENOG4105BZ1	(ABC) transporter
SanJ4211_0660	ENOG41067MG	lrgb family
SanJ4211_0661	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
SanJ4211_0662	ENOG4105CVG	Homoserine O-transsuccinylase
SanJ4211_0665	ENOG4105EGD	dinuclear metal center protein, YbgI family
SanJ4211_0666	ENOG4107VFR	oxidoreductase
SanJ4211_0669	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
SanJ4211_0671	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
SanJ4211_0672	ENOG4105CMR	udp-glucose 4-epimerase
SanJ4211_0674	ENOG4105CKK	Glycosyl transferase, family 2
SanJ4211_0679	ENOG4105CKK	Glycosyl transferase, family 2
SanJ4211_0680	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
SanJ4211_0684	ENOG4105EY8	ABC transporter
SanJ4211_0689	ENOG4107T7U	Sulfatase
SanJ4211_0690c	ENOG4105DC7	peptidase M24
SanJ4211_0691	ENOG4105ETE	Transcriptional regulator (LacI family
SanJ4211_0692	ENOG4105W2C	Glycosyl transferase
SanJ4211_0693	ENOG4105BZF	Glycosyl transferase (Group 1
SanJ4211_0695	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SanJ4211_0696	ENOG4105BZU	Histidine kinase
SanJ4211_0697	ENOG4105Q2H	domain protein
SanJ4211_0700	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
SanJ4211_0701	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
SanJ4211_0702	ENOG4108HCJ	Hydrolase
SanJ4211_0703	ENOG410667J	hydrolase
SanJ4211_0704	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
SanJ4211_0705c	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
SanJ4211_0706c	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
SanJ4211_0707c	ENOG4108NNR	transporter substrate-binding protein
SanJ4211_0708c	ENOG4108PJD	permease
SanJ4211_0711	ENOG410906U	SprT-like
SanJ4211_0713	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
SanJ4211_0714	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
SanJ4211_0715	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
SanJ4211_0720	ENOG4105CFP	Peptidase U32
SanJ4211_0722	ENOG4107UWA	esterase
SanJ4211_0725	ENOG4105C5H	ABC transporter
SanJ4211_0728c	ENOG4105F1K	Glutamine amidotransferase
SanJ4211_0729c	ENOG4105DMS	mur ligase
SanJ4211_0730	ENOG4105C8B	TIGR00159 family
SanJ4211_0732	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
SanJ4211_0733	ENOG4105EAC	phosphoserine phosphatase
SanJ4211_0734	ENOG4105BZW	Glycerate kinase
SanJ4211_0738	ENOG4105CAT	Cytidine monophosphate kinase
SanJ4211_0739	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
SanJ4211_0740	ENOG4105VJV	50s ribosomal protein L35
SanJ4211_0743	ENOG4108ZJ4	polysaccharide deacetylase
SanJ4211_0745c	ENOG4105EE0	oxidoreductase
SanJ4211_0746	ENOG4105DBI	uridine monophosphokinase
SanJ4211_0748c	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
SanJ4211_0749c	ENOG410667J	hydrolase
SanJ4211_0750	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
SanJ4211_0752	ENOG4105D4A	Cell wall formation (By similarity)
SanJ4211_0753	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
SanJ4211_0754	ENOG4105F38	ABC transporter, permease
SanJ4211_0755	ENOG4105D38	putrescine abc transporter
SanJ4211_0756	ENOG4107RUE	extracellular solute-binding protein family 1
SanJ4211_0759c	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
SanJ4211_0761	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
SanJ4211_0762	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
SanJ4211_0763	ENOG4105C3J	Cysteine desulfurase
SanJ4211_0764	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
SanJ4211_0765	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
SanJ4211_0767	ENOG4105K46	50S ribosomal protein l27
SanJ4211_0769	ENOG4105VFE	sira family
SanJ4211_0770	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
SanJ4211_0773c	ENOG4105VPX	protein, conserved in bacteria
SanJ4211_0776	ENOG4105DUM	transcriptional regulator, lysR family
SanJ4211_0778	ENOG4105C34	Pseudouridine synthase
SanJ4211_0781	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
SanJ4211_0785	ENOG4107R4J	Chloride channel
SanJ4211_0786	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
SanJ4211_0787	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
SanJ4211_0790	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
SanJ4211_0791	ENOG4107X35	defense response to bacterium
SanJ4211_0792	ENOG4105BZ1	(ABC) transporter
SanJ4211_0793	ENOG4105BZ1	(ABC) transporter
SanJ4211_0794c	ENOG4105C5H	ABC transporter
SanJ4211_0798	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
SanJ4211_0803	ENOG4105CSA	Coproporphyrinogen iii oxidase
SanJ4211_0805	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
SanJ4211_0809	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
SanJ4211_0810	ENOG4105CHW	UPF0052 protein
SanJ4211_0811	ENOG4105CIE	May be required for sporulation (By similarity)
SanJ4211_0812	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
SanJ4211_0814	ENOG4105CXT	aspartate transcarbamylase
SanJ4211_0815	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
SanJ4211_0816	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
SanJ4211_0817	ENOG4107RGD	Major Facilitator superfamily
SanJ4211_0818	ENOG4105DND	Transcriptional regulator
SanJ4211_0825	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
SanJ4211_0826	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
SanJ4211_0828	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
SanJ4211_0830	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
SanJ4211_0833	ENOG4106E6V	UPF0346 protein
SanJ4211_0834	ENOG4105C9A	Phoh family
SanJ4211_0837c	ENOG4105DCF	alanine dehydrogenase
SanJ4211_0843	ENOG4105BZ1	(ABC) transporter
SanJ4211_0844	ENOG4105BZ1	(ABC) transporter
SanJ4211_0845	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
SanJ4211_0846	ENOG4107YR5	Diacylglycerol kinase
SanJ4211_0847	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
SanJ4211_0850	ENOG4108JW7	Maf-like protein
SanJ4211_0853	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
SanJ4211_0854	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
SanJ4211_0855	ENOG4105C6X	Major Facilitator
SanJ4211_0857	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
SanJ4211_0858	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
SanJ4211_0859c	ENOG4105DQ6	Transposase
SanJ4211_0861	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
SanJ4211_0862	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
SanJ4211_0866	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
SanJ4211_0867	ENOG4108Z4K	mutator MutT protein
SanJ4211_0868	ENOG4105CD3	dihydroorotase
SanJ4211_0869	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
SanJ4211_0875	ENOG4108U05	Transcriptional regulator
SanJ4211_0877c	ENOG4105WH5	Teichoic acid glycosylation protein
SanJ4211_0878	ENOG410807C	QueT transporter
SanJ4211_0879c	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
SanJ4211_0880	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
SanJ4211_0881	ENOG4105CBD	Diacylglycerol kinase
SanJ4211_0882	ENOG4108IUM	Glycogen debranching enzyme
SanJ4211_0883	ENOG4105K5M	30s ribosomal protein S16
SanJ4211_0884	ENOG4105VB6	UPF0109 protein
SanJ4211_0885c	ENOG4105DQ6	Transposase
SanJ4211_0887c	ENOG4105RNB	
SanJ4211_0889	ENOG4106N3A	copper homeostasis protein cutc
SanJ4211_0890	ENOG4105UNS	Pfam:DUF419
SanJ4211_0891	ENOG4105BZ1	(ABC) transporter
SanJ4211_0892	ENOG4105BZ1	(ABC) transporter
SanJ4211_0896	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
SanJ4211_0900	ENOG4105VCC	30S ribosomal protein S21
SanJ4211_0901c	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
SanJ4211_0902	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
SanJ4211_0903	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SanJ4211_0904	ENOG4105VG1	fes assembly suf system protein
SanJ4211_0905	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
SanJ4211_0906	ENOG4107QIV	Cytochrome c biogenesis protein
SanJ4211_0907	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SanJ4211_0908	ENOG4105E0X	reductase
SanJ4211_0909	ENOG4105WH1	Two component transcriptional regulator luxr family
SanJ4211_0910	ENOG4105C2F	Histidine kinase
SanJ4211_0913c	ENOG4108IUW	ABC transporter
SanJ4211_0914c	ENOG4107EFR	Flavocytochrome c
SanJ4211_0919c	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SanJ4211_0924	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
SanJ4211_0925	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
SanJ4211_0926	ENOG4105C2W	permease
SanJ4211_0927	ENOG4107QMU	Mate efflux family protein
SanJ4211_0928c	ENOG41069HH	4-oxalocrotonate tautomerase
SanJ4211_0929	ENOG4107104	thymidine kinase
SanJ4211_0930	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
SanJ4211_0931	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
SanJ4211_0933	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
SanJ4211_0935	ENOG41065S2	pneumococcal vaccine antigen
SanJ4211_0937c	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
SanJ4211_0938	ENOG4105FDP	GntR family transcriptional regulator
SanJ4211_0940	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SanJ4211_0941	ENOG4108XZ3	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity)
SanJ4211_0942c	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
SanJ4211_0944c	ENOG4105DF9	Lipoate-protein, ligase
SanJ4211_0946c	ENOG4107QKR	Dehydrogenase
SanJ4211_0948c	ENOG4107RUY	(E1 component), alpha subunit
SanJ4211_0952c	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
SanJ4211_0953c	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
SanJ4211_0954c	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
SanJ4211_0955c	ENOG4105C79	DNA protecting protein DprA
SanJ4211_0956c	ENOG4108UW5	maltose o-acetyltransferase
SanJ4211_0957c	ENOG4105CID	antiterminator
SanJ4211_0959c	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
SanJ4211_0960c	ENOG4105C8F	Beta-lactamase domain protein
SanJ4211_0961c	ENOG4105C1G	acyl-Coa dehydrogenase
SanJ4211_0962c	ENOG4105DZ2	Transcriptional regulator
SanJ4211_0963c	ENOG4107QNJ	CoA-transferase subunit B
SanJ4211_0965c	ENOG4105E39	Enoyl-CoA hydratase
SanJ4211_0966c	ENOG4105CHU	acetyl-coa acetyltransferase
SanJ4211_0967c	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
SanJ4211_0968c	ENOG4105C1G	acyl-Coa dehydrogenase
SanJ4211_0969	ENOG4107QN2	dihydrolipoyl dehydrogenase
SanJ4211_0970c	ENOG4108Z6X	(sortase) family
SanJ4211_0971c	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
SanJ4211_0972	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
SanJ4211_0974c	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
SanJ4211_0976c	ENOG4105CM2	brancheD-chain amino acid aminotransferase
SanJ4211_0977c	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
SanJ4211_0978c	ENOG41075D4	Aminoglycoside 6-adenylyltransferase
SanJ4211_0981c	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
SanJ4211_0982	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
SanJ4211_0983c	ENOG4105CGH	5'-nucleotidase
SanJ4211_0984c	ENOG4105N21	Membrane
SanJ4211_0985c	ENOG4108UK2	deaminase
SanJ4211_0986c	ENOG41082JN	Transcriptional regulator
SanJ4211_0995c	ENOG4105F22	Major Facilitator Superfamily
SanJ4211_0996c	ENOG4105C5S	asparaginyl-tRNA synthetase
SanJ4211_0998c	ENOG4105CHM	Aminotransferase
SanJ4211_1002c	ENOG4105D1Q	UPF0246 protein
SanJ4211_1004	ENOG4108UT2	hemolysin iii
SanJ4211_1006c	ENOG4105UIB	(ABC) transporter
SanJ4211_1007c	ENOG4108JQ9	ABC transporter
SanJ4211_1008c	ENOG4105DIH	basic membrane
SanJ4211_1009c	ENOG4105KG3	cytidine deaminase
SanJ4211_1010c	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
SanJ4211_1012c	ENOG4107Y49	methyltransferase
SanJ4211_1013	ENOG4105CS9	pantothenic acid kinase
SanJ4211_1019c	ENOG4105US7	Histidine kinase
SanJ4211_1020c	ENOG4108STX	response regulator
SanJ4211_1031	ENOG4105CNU	cell division protein FtsK
SanJ4211_1037c	ENOG4105DKQ	ROK family
SanJ4211_1038	ENOG4108KB2	LysR family Transcriptional regulator
SanJ4211_1043c	ENOG4105CK1	PTS System
SanJ4211_1045c	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
SanJ4211_1046c	ENOG4105D6E	homoserine dehydrogenase
SanJ4211_1047	ENOG4107BJW	polysaccharide deacetylase
SanJ4211_1049c	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SanJ4211_1051c	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
SanJ4211_1052c	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
SanJ4211_1053	ENOG4105CQ4	Transcriptional regulator
SanJ4211_1054	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
SanJ4211_1057c	ENOG4105C6E	dna polymerase iii
SanJ4211_1058c	ENOG4108ZGC	gaf domain protein
SanJ4211_1062c	ENOG4105DSE	periplasmic solute binding protein
SanJ4211_1063c	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
SanJ4211_1064c	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
SanJ4211_1065c	ENOG4105BZ1	(ABC) transporter
SanJ4211_1069c	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SanJ4211_1076c	ENOG4105XEZ	This methylase recognizes the double-stranded sequence TCGA, causes specific methylation on A-4 on both strands and protects the DNA from cleavage by the
SanJ4211_1077c	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
SanJ4211_1078c	ENOG4108VZM	50s ribosomal protein L10
SanJ4211_1079c	ENOG41086D8	Transcriptional regulator
SanJ4211_1080c	ENOG41079CX	
SanJ4211_1081c	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
SanJ4211_1082c	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
SanJ4211_1085c	ENOG4107Y3V	-acetyltransferase
SanJ4211_1086c	ENOG4105CKU	formyltetrahydrofolate synthetase
SanJ4211_1088	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
SanJ4211_1089	ENOG4105FH5	Membrane
SanJ4211_1093c	ENOG4108IJ2	phosphate acetyltransferase
SanJ4211_1094c	ENOG4105EMS	pseudouridine synthase
SanJ4211_1095c	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
SanJ4211_1098	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
SanJ4211_1099	ENOG4105C3J	Cysteine desulfurase
SanJ4211_1101	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
SanJ4211_1103c	ENOG4105W5Q	DNA repair protein (RadC
SanJ4211_1105c	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
SanJ4211_1106c	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
SanJ4211_1107c	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
SanJ4211_1108c	ENOG4105E2Z	phosphate ABC transporter (Permease
SanJ4211_1109c	ENOG4105C8U	phosphate abc transporter
SanJ4211_1110c	ENOG4105CVA	phosphate
SanJ4211_1111c	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
SanJ4211_1112c	ENOG4105ECY	inositol monophosphatase
SanJ4211_1113c	ENOG4105WBI	UPF0223 protein
SanJ4211_1114c	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
SanJ4211_1115c	ENOG4105DTN	riboflavin biosynthesis protein ribF
SanJ4211_1116c	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
SanJ4211_1119c	ENOG4105BZ1	(ABC) transporter
SanJ4211_1121c	ENOG4105D29	Helix-turn-helix type 11 domain protein
SanJ4211_1123c	ENOG4105C4R	Atp-dependent dna helicase
SanJ4211_1125c	ENOG4106PMH	Extracellular solute-binding protein family 3
SanJ4211_1126c	ENOG4105CDA	abc transporter atp-binding protein
SanJ4211_1127c	ENOG4105E5Q	amino acid AbC transporter
SanJ4211_1129c	ENOG4105CA9	Pyruvate kinase
SanJ4211_1130c	ENOG4105CTQ	phosphohexokinase
SanJ4211_1131c	ENOG4105C0B	DNA polymerase III (alpha subunit)
SanJ4211_1132	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
SanJ4211_1133	ENOG4105CZV	ABC transporter
SanJ4211_1135c	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
SanJ4211_1138c	ENOG4108IXY	short-chain dehydrogenase reductase
SanJ4211_1142c	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
SanJ4211_1143c	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
SanJ4211_1145c	ENOG4107RBB	ABC transporter, permease
SanJ4211_1146c	ENOG4105C19	ABC transporter
SanJ4211_1148	ENOG4105DC8	reductase
SanJ4211_1149	ENOG4105VKD	bioY protein
SanJ4211_1153c	ENOG4108W2W	
SanJ4211_1158c	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
SanJ4211_1161c	ENOG4105C5H	ABC transporter
SanJ4211_1162c	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
SanJ4211_1163c	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
SanJ4211_1164c	ENOG4105EPR	degv family
SanJ4211_1166c	ENOG4105DM4	PTS System
SanJ4211_1167c	ENOG4105DE4	1-phosphofructokinase
SanJ4211_1168c	ENOG4105E98	transcriptional regulator DeoR family
SanJ4211_1170	ENOG4105CAY	ferredoxin--nadp reductase
SanJ4211_1179	ENOG4105DQ6	Transposase
SanJ4211_1182c	ENOG4108IMY	Transcriptional regulator
SanJ4211_1184c	ENOG4105CS2	ec 3.2.1.21
SanJ4211_1187c	ENOG4105CID	antiterminator
SanJ4211_1188c	ENOG4105D2M	Aldolase
SanJ4211_1189c	ENOG4105DE4	1-phosphofructokinase
SanJ4211_1190c	ENOG4108YZG	isomerase
SanJ4211_1191c	ENOG4105RSI	Galactose-6-phosphate isomerase subunit LacA
SanJ4211_1192c	ENOG4105E98	transcriptional regulator DeoR family
SanJ4211_1193c	ENOG4105MU5	relaxase mobilization nuclease domain protein
SanJ4211_1196c	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
SanJ4211_1198c	ENOG4108WZA	zeta toxin
SanJ4211_1224c	ENOG4105DVF	Cytosine-specific methyltransferase
SanJ4211_1228c	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
SanJ4211_1229c	ENOG4108RCF	TRANSCRIPTIONal
SanJ4211_1230c	ENOG4105CQC	Prephenate dehydratase
SanJ4211_1231c	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
SanJ4211_1232c	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
SanJ4211_1235c	ENOG4105WZB	UPF0342 protein
SanJ4211_1236c	ENOG4105EVN	Prephenate dehydrogenase
SanJ4211_1239c	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
SanJ4211_1240c	ENOG4105D49	3-dehydroquinate synthase
SanJ4211_1241c	ENOG4105E2X	shikimate dehydrogenase
SanJ4211_1242c	ENOG4105FF2	Type I DHQase
SanJ4211_1243c	ENOG4105DR4	Methyltransferase
SanJ4211_1246c	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
SanJ4211_1248c	ENOG4105E66	phosphoriboisomerase A
SanJ4211_1249	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
SanJ4211_1254c	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
SanJ4211_1257c	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
SanJ4211_1258c	ENOG4105CNI	cell division protein FtsW
SanJ4211_1261	ENOG4108Z66	YbaK ebsC protein
SanJ4211_1262	ENOG4108TGR	phosphatase
SanJ4211_1263	ENOG4105CRK	lysyL-tRNA synthetase
SanJ4211_1268c	ENOG4105C6N	Formate acetyltransferase
SanJ4211_1269c	ENOG4105CK1	PTS System
SanJ4211_1271c	ENOG4105VCP	PTS System
SanJ4211_1272c	ENOG4105DKT	Transcriptional regulator
SanJ4211_1273c	ENOG4105N2W	Transcriptional regulator
SanJ4211_1275	ENOG4105F1A	Pyruvate formate-lyase
SanJ4211_1276c	ENOG4108Z40	Transcriptional regulator
SanJ4211_1279c	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SanJ4211_1284c	ENOG4105NQC	Flavodoxin
SanJ4211_1285	ENOG4105SFS	phosphoesterase RecJ domain protein
SanJ4211_1286	ENOG41082DI	50s ribosomal protein l31
SanJ4211_1290c	ENOG4108IJ8	ABC transporter
SanJ4211_1291c	ENOG4108HQR	Glycine betaine
SanJ4211_1293c	ENOG4108RG0	uracil-dna glycosylase
SanJ4211_1295c	ENOG4107QSE	Dipeptidase
SanJ4211_1297c	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
SanJ4211_1298c	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
SanJ4211_1299c	ENOG4105KRI	phosphocarrier protein (HPr
SanJ4211_1300	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
SanJ4211_1302	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
SanJ4211_1306c	ENOG4105VZ8	Transcriptional regulator
SanJ4211_1309c	ENOG4105F6E	Acyl-transferase
SanJ4211_1310	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
SanJ4211_1311	ENOG41060K3	Methyltransferase
SanJ4211_1312	ENOG4105VC4	domain protein
SanJ4211_1314c	ENOG4105CK1	PTS System
SanJ4211_1315c	ENOG4105VCP	PTS System
SanJ4211_1316c	ENOG4105CS2	ec 3.2.1.21
SanJ4211_1317c	ENOG4105CID	antiterminator
SanJ4211_1318c	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
SanJ4211_1320c	ENOG4105DT3	PTS system, galactitol-specific IIc component
SanJ4211_1325c	ENOG4105E98	transcriptional regulator DeoR family
SanJ4211_1326	ENOG4105D2M	Aldolase
SanJ4211_1327c	ENOG4105C1J	atp-dependent rna helicase
SanJ4211_1331c	ENOG41067QW	Transcriptional regulator
SanJ4211_1335c	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
SanJ4211_1336c	ENOG4105CPF	Cell wall formation (By similarity)
SanJ4211_1337c	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
SanJ4211_1338c	ENOG4107RF6	penicillin-binding protein
SanJ4211_1341c	ENOG4105KDP	XRE family
SanJ4211_1342c	ENOG4105MRD	Phage derived protein Gp49-like (DUF891)
SanJ4211_1345c	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
SanJ4211_1347c	ENOG41068JE	domain protein
SanJ4211_1399c	ENOG4105K70	DNA-binding protein
SanJ4211_1400c	ENOG4108RCR	degv family
SanJ4211_1402	ENOG4105DHS	permease protein
SanJ4211_1403	ENOG4105CM4	permease protein
SanJ4211_1404	ENOG4108IPW	abc transporter atp-binding protein
SanJ4211_1405	ENOG4108MES	Periplasmic binding protein
SanJ4211_1406c	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
SanJ4211_1407c	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
SanJ4211_1408c	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
SanJ4211_1409c	ENOG4105DX0	Hemolysin A
SanJ4211_1411c	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
SanJ4211_1412c	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
SanJ4211_1415c	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
SanJ4211_1416c	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
SanJ4211_1417	ENOG4107WD8	ABC transporter, permease
SanJ4211_1424c	ENOG4107IN1	Protein of unknown function (DUF1797)
SanJ4211_1425	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
SanJ4211_1428	ENOG4105M6F	mutator MutT protein
SanJ4211_1430c	ENOG4107SUZ	Sodium/hydrogen exchanger family
SanJ4211_1433c	ENOG4105N5T	Radical SAM Protein
SanJ4211_1435c	ENOG410841Q	phosphoesterase PA-phosphatase related protein
SanJ4211_1436c	ENOG4108SAX	Membrane
SanJ4211_1438	ENOG4105C1A	potassium transporter peripheral membrane
SanJ4211_1439	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
SanJ4211_1443c	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
SanJ4211_1444c	ENOG4105FE9	pseudouridine synthase
SanJ4211_1445c	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
SanJ4211_1446c	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
SanJ4211_1447c	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
SanJ4211_1450c	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
SanJ4211_1451c	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
SanJ4211_1456c	ENOG4108RWN	rrna methyltransferase
SanJ4211_1458	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
SanJ4211_1460c	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
SanJ4211_1465c	ENOG4105DFU	Cell wall formation (By similarity)
SanJ4211_1467c	ENOG4105C0D	helicase
SanJ4211_1469c	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
SanJ4211_1474c	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
SanJ4211_1477c	ENOG4105CI1	PTS System
SanJ4211_1479c	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SanJ4211_1480c	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
SanJ4211_1486c	ENOG4105D0M	Protease HtpX homolog
SanJ4211_1487c	ENOG4108V0P	LemA family
SanJ4211_1488	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
SanJ4211_1489c	ENOG4105X1N	Glycosyl transferase family 8
SanJ4211_1490c	ENOG4105EMU	Dehydrogenase
SanJ4211_1492c	ENOG4108JJB	ABC transporter
SanJ4211_1494c	ENOG4108V7D	UPF0397 protein
SanJ4211_1497c	ENOG4105DQ6	Transposase
SanJ4211_1499c	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
SanJ4211_1500c	ENOG4105D01	(LipO)protein
SanJ4211_1501c	ENOG4105EAB	amino acid AbC transporter
SanJ4211_1504c	ENOG4105CHH	sulfate transporter
SanJ4211_1505c	ENOG4108IMY	Transcriptional regulator
SanJ4211_1506c	ENOG4105CDY	transcriptional regulatory protein
SanJ4211_1507c	ENOG4105CDE	UPF0348 protein
SanJ4211_1509c	ENOG4105DXX	methyltransferase
SanJ4211_1510c	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
SanJ4211_1511c	ENOG4108WF2	Metal Dependent Phosphohydrolase
SanJ4211_1512c	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
SanJ4211_1513c	ENOG410812S	Rna-binding protein
SanJ4211_1514c	ENOG4105CQW	ribosome biogenesis GTPase YqeH
SanJ4211_1515c	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
SanJ4211_1517c	ENOG4108UZ3	Transporter
SanJ4211_1518c	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
SanJ4211_1519c	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
SanJ4211_1520c	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
SanJ4211_1523c	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
SanJ4211_1524c	ENOG4105CHM	Aminotransferase
SanJ4211_1525	ENOG4107YZX	Universal stress protein
SanJ4211_1526c	ENOG4108KP7	hydrolase
SanJ4211_1527	ENOG4107RB3	L-asparaginase
SanJ4211_1528c	ENOG4105CB5	ATP-dependent DNA helicase recG
SanJ4211_1529c	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
SanJ4211_1530c	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
SanJ4211_1531c	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
SanJ4211_1532c	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
SanJ4211_1533c	ENOG4105C0X	amino acid
SanJ4211_1534c	ENOG4105DG6	mannose-6-phosphate isomerase
SanJ4211_1535c	ENOG4108TZY	GntR Family Transcriptional Regulator
SanJ4211_1536c	ENOG4105CK1	PTS System
SanJ4211_1537	ENOG4105CS2	ec 3.2.1.21
SanJ4211_1538c	ENOG4105VCP	PTS System
SanJ4211_1539c	ENOG4105VZJ	PTS System
SanJ4211_1540c	ENOG4105BZ1	(ABC) transporter
SanJ4211_1543c	ENOG4107YDN	peptide deformylase
SanJ4211_1544c	ENOG4105EVU	fructokinase
SanJ4211_1545c	ENOG4105C5Y	PTS System
SanJ4211_1547	ENOG4105ETE	Transcriptional regulator (LacI family
SanJ4211_1548c	ENOG410667J	hydrolase
SanJ4211_1549c	ENOG4108JQ7	(ABC) transporter
SanJ4211_1550c	ENOG4105C3U	ABC transporter
SanJ4211_1551c	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
SanJ4211_1552c	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
SanJ4211_1553c	ENOG4105DIB	Oligopeptide-binding protein
SanJ4211_1554c	ENOG4105DIB	Oligopeptide-binding protein
SanJ4211_1556c	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
SanJ4211_1557c	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
SanJ4211_1558c	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
SanJ4211_1560c	ENOG4105PUK	Membrane
SanJ4211_1561c	ENOG4105DWF	phosphomethylpyrimidine kinase
SanJ4211_1562c	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
SanJ4211_1564c	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
SanJ4211_1566c	ENOG4105CFG	Acts as a chaperone (By similarity)
SanJ4211_1567c	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SanJ4211_1568c	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
SanJ4211_1569c	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
SanJ4211_1570c	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
SanJ4211_1571c	ENOG4105CAG	UPF0210 protein
SanJ4211_1572c	ENOG4105VUC	UPF0237 protein
SanJ4211_1574c	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
SanJ4211_1575c	ENOG4107R8N	Glycosyl transferase, family 2
SanJ4211_1577c	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
SanJ4211_1590	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SanJ4211_1591c	ENOG4108UJD	30S ribosomal protein S9
SanJ4211_1592c	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
SanJ4211_1594c	ENOG4105M0M	Tetracycline resistance protein
SanJ4211_1595c	ENOG4105C2N	RNA methyltransferase TrmH family group 3
SanJ4211_1596c	ENOG4108IJ9	(ABC) transporter
SanJ4211_1598c	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SanJ4211_1599c	ENOG4105C8N	cysteinyl-tRNA synthetase
SanJ4211_1600c	ENOG4105D7W	serine acetyltransferase
SanJ4211_1601c	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
SanJ4211_1602	ENOG4105DPN	Oligoendopeptidase f
SanJ4211_1605c	ENOG4105K63	Thioredoxin
SanJ4211_1607c	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
SanJ4211_1617c	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
SanJ4211_1619c	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
SanJ4211_1620c	ENOG4108IUM	Glycogen debranching enzyme
SanJ4211_1623c	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
SanJ4211_1627c	ENOG4108X4Q	Hydrolase
SanJ4211_1629c	ENOG4105M7K	Involved in the transcription termination process (By similarity)
SanJ4211_1631c	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
SanJ4211_1632c	ENOG4105DC7	peptidase M24
SanJ4211_1634c	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
SanJ4211_1637c	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
SanJ4211_1638c	ENOG4108UUM	single-stranded DNA-binding protein
SanJ4211_1645c	ENOG4105CS2	ec 3.2.1.21
SanJ4211_1646c	ENOG4105CS2	ec 3.2.1.21
SanJ4211_1648c	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
SanJ4211_1650	ENOG4108JJB	ABC transporter
SanJ4211_1655c	ENOG4105BZU	Histidine kinase
SanJ4211_1656c	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
SanJ4211_1657c	ENOG4105CS2	ec 3.2.1.21
SanJ4211_1659c	ENOG4105C7K	acetolactate synthase
SanJ4211_1660c	ENOG4108VXD	carboxy-peptidase
SanJ4211_1665c	ENOG4108HCJ	Hydrolase
SanJ4211_1667c	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
SanJ4211_1672c	ENOG4105C5Y	PTS System
SanJ4211_1677	ENOG4108AQF	aminoglycoside N(3)-acetyltransferase
SanJ4211_1680c	ENOG4105EBR	Carboxylesterase
SanJ4211_1681c	ENOG4105VCP	PTS System
SanJ4211_1682c	ENOG4105VZJ	PTS System
SanJ4211_1684c	ENOG4105CK1	PTS System
SanJ4211_1685	ENOG4105E2R	ROK family
SanJ4211_1687c	ENOG4105E0X	reductase
SanJ4211_1688c	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
SanJ4211_1689	ENOG4107R37	Glutamate dehydrogenase
SanJ4211_1691c	ENOG4105D8X	mechanosensitive ion channel
SanJ4211_1693c	ENOG4105K63	Thioredoxin
SanJ4211_1695c	ENOG4105C98	muts2 protein
SanJ4211_1699	ENOG4105C3F	Signal peptidase i
SanJ4211_1701	ENOG4105C7H	Helicase, RecD TraA family
SanJ4211_1704	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
SanJ4211_1705	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
SanJ4211_1710c	ENOG41072GX	Peptidase M22 Glycoprotease
SanJ4211_1713c	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
SanJ4211_1714c	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
SanJ4211_1715c	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
SanJ4211_1716c	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
SanJ4211_1718c	ENOG4105DFT	pur operon repressor
SanJ4211_1719c	ENOG4105EQI	Metal Dependent Phosphohydrolase
SanJ4211_1720c	ENOG4107QSV	RmuC domain protein
SanJ4211_1721c	ENOG4105FJ0	thiamine
SanJ4211_1722c	ENOG4105DJV	ribulose-phosphate 3-epimerase
SanJ4211_1723c	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
SanJ4211_1724c	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
SanJ4211_1726c	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
SanJ4211_1728c	ENOG4105F8V	Hydrolase, tatD family
SanJ4211_1729c	ENOG41084B3	50S ribosomal protein l34
SanJ4211_1733c	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
SanJ4211_1735c	ENOG4107QYV	phosphohexose isomerase
SanJ4211_1739c	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
SanJ4211_1746	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
SanJ4211_1747	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
SanJ4211_1753c	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
SanJ4211_1754c	ENOG4105CE9	30S ribosomal protein S2
SanJ4211_1756c	ENOG4108ZT0	50S ribosomal protein l17
SanJ4211_1757c	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
SanJ4211_1758c	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
SanJ4211_1759c	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SanJ4211_1760c	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
SanJ4211_1761c	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
SanJ4211_1762c	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
SanJ4211_1763c	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
SanJ4211_1764c	ENOG4105VPB	50S ribosomal protein L30
SanJ4211_1765c	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
SanJ4211_1767c	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
SanJ4211_1769c	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
SanJ4211_1770c	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
SanJ4211_1771c	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SanJ4211_1772c	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
SanJ4211_1773c	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
SanJ4211_1775c	ENOG41082SA	50s ribosomal protein l29
SanJ4211_1776c	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
SanJ4211_1777c	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
SanJ4211_1778c	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
SanJ4211_1780c	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SanJ4211_1781c	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
SanJ4211_1782c	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
SanJ4211_1783c	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
SanJ4211_1784c	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
SanJ4211_1787c	ENOG4105DBI	uridine monophosphokinase
SanJ4211_1788c	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
SanJ4211_1791c	ENOG4105K4P	CoA-binding domain protein
SanJ4211_1792c	ENOG4105C2M	dna polymerase I
SanJ4211_1793c	ENOG4108YBA	Histidine kinase
SanJ4211_1800c	ENOG4105GH9	galactofuranosyltransferase
SanJ4211_1802c	ENOG4105D5D	udp-galactopyranose mutase
SanJ4211_1803c	ENOG4105MEV	Acyl-transferase
SanJ4211_1806c	ENOG4105K64	Glycosyl transferase, family 2
SanJ4211_1814c	ENOG4105HTX	biosynthesis protein
SanJ4211_1815c	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
SanJ4211_1817c	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
SanJ4211_1821c	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
SanJ4211_1824c	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
SanJ4211_1826c	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
SanJ4211_1827c	ENOG4105VPH	UPF0473 protein
SanJ4211_1828c	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
SanJ4211_1829c	ENOG4105VBH	UPF0297 protein
SanJ4211_1832c	ENOG410888K	transcriptional regulator, Spx
SanJ4211_1833c	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
SanJ4211_1834c	ENOG4105CEV	competence damage-inducible protein
SanJ4211_1836c	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
SanJ4211_1837c	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
SanJ4211_1838	ENOG41067QW	Transcriptional regulator
SanJ4211_1839c	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
SanJ4211_1842c	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
SanJ4211_1843c	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
SanJ4211_1845c	ENOG4105MTF	NrdI protein
SanJ4211_1847c	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
SanJ4211_1848c	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
SanJ4211_1849	ENOG4107FKK	extracellular solute-binding protein family 1
SanJ4211_1850	ENOG4105D56	permease protein
SanJ4211_1851	ENOG4105EG2	ABC transporter, permease
SanJ4211_1852	ENOG4108VP7	maltodextrose utilization protein MalA
SanJ4211_1853	ENOG4105FKQ	transcriptional regulator
SanJ4211_1854	ENOG4108IUM	Glycogen debranching enzyme
SanJ4211_1855c	ENOG4107AYK	membrAne
SanJ4211_1858c	ENOG4105CUT	histidyl-tRNA synthetase
SanJ4211_1859	ENOG41086FC	50S ribosomal protein l32
SanJ4211_1862c	ENOG4107T65	Integrase
SanJ4211_1869	ENOG4105DQ6	Transposase
SanJ4211_1873	ENOG4105DJ2	Major Facilitator Superfamily
SanJ4211_1874c	ENOG4108VX5	3-methyladenine DNA glycosylase
SanJ4211_1875	ENOG410667J	hydrolase
SanJ4211_1876c	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
SanJ4211_1877c	ENOG4105X96	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
SanJ4211_1878c	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
SanJ4211_1889	ENOG4105J7I	hydrolase
SanJ4211_1892c	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
SanJ4211_1895c	ENOG4105CDU	Replicative dna helicase
SanJ4211_1896c	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
SanJ4211_1898c	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
SanJ4211_1899c	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
SanJ4211_1900c	ENOG41068KG	domain protein
SanJ4211_1902	ENOG4105EJQ	L-serine dehydratase
SanJ4211_1905c	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
SanJ4211_1906c	ENOG4108JJB	ABC transporter
SanJ4211_1907c	ENOG4108JJB	ABC transporter
SanJ4211_1908c	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
SanJ4211_1913	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
SanJ4211_1914c	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
SanJ4211_1915c	ENOG4105C31	Tryptophanyl-tRNA synthetase
SanJ4211_1916c	ENOG4105CMR	udp-glucose 4-epimerase
SanJ4211_1917c	ENOG4105CP7	Triose-phosphate isomerase
SanJ4211_1919	ENOG4105C5H	ABC transporter
SanJ4211_1924c	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
SanJ4211_1925	ENOG4105C0H	protease
SanJ4211_1926	ENOG4105FA0	parb-like partition protein