locus-tag	class	description
SanJ4211_0002	COG0592	DNA-directed DNA polymerase activity
SanJ4211_0005	COG0012	GTP binding
SanJ4211_0006	COG0193	aminoacyl-tRNA hydrolase activity
SanJ4211_0007	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SanJ4211_0008	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SanJ4211_0012	COG0037	tRNA processing
SanJ4211_0014	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SanJ4211_0016	COG1792	Involved in formation and maintenance of cell shape
SanJ4211_0018	COG3942	CHAP domain
SanJ4211_0019	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SanJ4211_0020	COG0436	Aminotransferase
SanJ4211_0021	COG1381	Involved in DNA repair and RecF pathway recombination
SanJ4211_0023	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SanJ4211_0024	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SanJ4211_0027	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SanJ4211_0028	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SanJ4211_0030c	COG3942	CHAP domain
SanJ4211_0032	COG0151	Belongs to the GarS family
SanJ4211_0035	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SanJ4211_0040	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SanJ4211_0041c	COG2376	Dihydroxyacetone kinase
SanJ4211_0043	COG2376	Dihydroxyacetone kinase
SanJ4211_0044	COG1461	Dihydroxyacetone kinase
SanJ4211_0045	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SanJ4211_0046	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SanJ4211_0050	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SanJ4211_0052	COG3716	PTS system mannose fructose sorbose family IID component
SanJ4211_0054	COG2222	sugar isomerase
SanJ4211_0055	COG3684	Belongs to the aldolase LacD family
SanJ4211_0056	COG2017	converts alpha-aldose to the beta-anomer
SanJ4211_0057	COG2255	four-way junction helicase activity
SanJ4211_0059	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SanJ4211_0062	COG1012	belongs to the aldehyde dehydrogenase family
SanJ4211_0062	COG1454	alcohol dehydrogenase
SanJ4211_0063	COG1454	alcohol dehydrogenase
SanJ4211_0064	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SanJ4211_0066	COG1175	transmembrane transport
SanJ4211_0067	COG0395	ABC-type sugar transport system, permease component
SanJ4211_0070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SanJ4211_0074	COG1269	ATP hydrolysis coupled proton transport
SanJ4211_0075	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SanJ4211_0077	COG1527	subunit (C
SanJ4211_0078	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
SanJ4211_0080	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
SanJ4211_0081	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
SanJ4211_0082	COG1394	ATPase activity, coupled to movement of substances
SanJ4211_0086	COG1309	transcriptional regulator
SanJ4211_0087	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SanJ4211_0091	COG3759	membrane
SanJ4211_0092	COG1914	H( )-stimulated, divalent metal cation uptake system
SanJ4211_0097	COG1846	Transcriptional regulator
SanJ4211_0098	COG1121	(ABC) transporter
SanJ4211_0099	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SanJ4211_0100	COG0803	Belongs to the bacterial solute-binding protein 9 family
SanJ4211_0100	COG3443	Belongs to the bacterial solute-binding protein 9 family
SanJ4211_0102	COG2217	Heavy metal translocating P-type atpase
SanJ4211_0104c	COG0564	pseudouridine synthase activity
SanJ4211_0105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SanJ4211_0108c	COG4974	Belongs to the 'phage' integrase family
SanJ4211_0122	COG0305	Participates in initiation and elongation during chromosome replication
SanJ4211_0124	COG1484	DNA-dependent DNA replication
SanJ4211_0136	COG0582	viral genome integration into host DNA
SanJ4211_0171c	COG4115	mRNA cleavage
SanJ4211_0177	COG0789	Transcriptional regulator
SanJ4211_0178c	COG2081	HI0933 family
SanJ4211_0180	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SanJ4211_0181	COG0584	glycerophosphoryl diester phosphodiesterase
SanJ4211_0182c	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SanJ4211_0184	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SanJ4211_0187	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SanJ4211_0191	COG1304	FMN binding
SanJ4211_0193c	COG3425	synthase
SanJ4211_0196c	COG1882	Formate acetyltransferase
SanJ4211_0198	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SanJ4211_0201	COG0756	dUTP diphosphatase activity
SanJ4211_0203	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SanJ4211_0204	COG2171	N-acyltransferase activity
SanJ4211_0205	COG1473	amidohydrolase
SanJ4211_0206	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SanJ4211_0208c	COG2226	methyltransferase
SanJ4211_0209c	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SanJ4211_0211	COG0085	RNA polymerase activity
SanJ4211_0212	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SanJ4211_0213	COG0126	phosphoglycerate kinase activity
SanJ4211_0215	COG0789	Transcriptional regulator
SanJ4211_0216	COG0174	glutamine synthetase
SanJ4211_0218	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SanJ4211_0219	COG1459	type II secretion system
SanJ4211_0220	COG4537	Required for transformation and DNA binding
SanJ4211_0226	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SanJ4211_0230	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SanJ4211_0231	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
SanJ4211_0241c	COG0741	lytic transglycosylase activity
SanJ4211_0241c	COG0791	NLP P60 protein
SanJ4211_0247c	COG2946	Replication initiation factor
SanJ4211_0248c	COG1674	ftsk spoiiie
SanJ4211_0251	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SanJ4211_0252	COG4589	Belongs to the CDS family
SanJ4211_0253	COG0750	zinc metalloprotease
SanJ4211_0254	COG0442	prolyl-tRNA aminoacylation
SanJ4211_0256	COG0285	dihydrofolate synthase activity
SanJ4211_0258c	COG1363	Peptidase, m42
SanJ4211_0260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SanJ4211_0261	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SanJ4211_0264	COG4585	Histidine kinase
SanJ4211_0265	COG2197	response regulator
SanJ4211_0269	COG3715	PTS system
SanJ4211_0270	COG3716	PTS system mannose fructose sorbose family IID component
SanJ4211_0272	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SanJ4211_0273	COG0459	protein refolding
SanJ4211_0276	COG1428	Deoxynucleoside kinase
SanJ4211_0277	COG1418	mRNA catabolic process
SanJ4211_0280c	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SanJ4211_0284	COG2264	protein methyltransferase activity
SanJ4211_0285	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SanJ4211_0288	COG1490	D-aminoacyl-tRNA deacylase activity
SanJ4211_0293	COG3590	peptidase
SanJ4211_0294	COG4988	ABC transporter
SanJ4211_0295	COG1132	(ABC) transporter
SanJ4211_0297c	COG0527	aspartate kinase activity
SanJ4211_0298	COG1024	Enoyl-CoA hydratase
SanJ4211_0300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SanJ4211_0302	COG2070	2-Nitropropane dioxygenase
SanJ4211_0303	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SanJ4211_0304	COG1028	Short-chain dehydrogenase reductase Sdr
SanJ4211_0305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SanJ4211_0307	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SanJ4211_0308	COG0439	Biotin carboxylase
SanJ4211_0309	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SanJ4211_0310	COG0825	malonyl-CoA metabolic process
SanJ4211_0311	COG0586	Pfam SNARE associated Golgi protein
SanJ4211_0312c	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SanJ4211_0314c	COG3716	PTS system mannose fructose sorbose family IID component
SanJ4211_0315c	COG3715	PTS system
SanJ4211_0317c	COG0561	phosphatase activity
SanJ4211_0319	COG2252	PERMEase
SanJ4211_0320	COG0802	atpase or kinase
SanJ4211_0322	COG1316	TRANSCRIPTIONal
SanJ4211_0324c	COG0537	adenosine 5'-monophosphoramidase activity
SanJ4211_0325	COG1131	(ABC) transporter
SanJ4211_0327	COG0510	thiamine kinase activity
SanJ4211_0328	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SanJ4211_0330	COG0779	Required for maturation of 30S ribosomal subunits
SanJ4211_0331	COG0195	Participates in both transcription termination and antitermination
SanJ4211_0332	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SanJ4211_0335	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SanJ4211_0336	COG1283	sodium-dependent phosphate transmembrane transporter activity
SanJ4211_0340	COG0656	L-ascorbic acid biosynthetic process
SanJ4211_0344	COG0752	glycyl-tRNA synthetase alpha subunit
SanJ4211_0345	COG0751	glycine-tRNA ligase activity
SanJ4211_0346	COG4224	UPF0291 protein
SanJ4211_0348c	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SanJ4211_0351	COG0275	rRNA processing
SanJ4211_0353	COG0768	penicillin binding
SanJ4211_0354	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SanJ4211_0355	COG4166	transmembrane transport
SanJ4211_0356	COG0191	fructose-bisphosphate aldolase activity
SanJ4211_0360	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SanJ4211_0362	COG1461	Dihydroxyacetone kinase
SanJ4211_0364	COG1131	(ABC) transporter
SanJ4211_0365	COG0842	Transport permease protein
SanJ4211_0366	COG4585	Histidine kinase
SanJ4211_0367	COG2197	response regulator
SanJ4211_0370c	COG1126	abc transporter atp-binding protein
SanJ4211_0371c	COG0765	amino acid transport
SanJ4211_0373	COG1968	undecaprenyl-diphosphatase activity
SanJ4211_0375	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SanJ4211_0376	COG4862	establishment of competence for transformation
SanJ4211_0377	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SanJ4211_0379	COG0719	Fe-S assembly protein
SanJ4211_0380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SanJ4211_0382c	COG1686	Belongs to the peptidase S11 family
SanJ4211_0383	COG0513	Belongs to the DEAD box helicase family
SanJ4211_0385	COG1126	abc transporter atp-binding protein
SanJ4211_0388	COG0492	ferredoxin-NADP+ reductase activity
SanJ4211_0389	COG1113	amino acid transport
SanJ4211_0390	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SanJ4211_0391	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SanJ4211_0392	COG3579	cysteine-type endopeptidase activity
SanJ4211_0393c	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SanJ4211_0394c	COG3331	DNA recombination
SanJ4211_0395	COG4474	Belongs to the UPF0398 family
SanJ4211_0396	COG3599	regulation of cell shape
SanJ4211_0397	COG0116	Belongs to the methyltransferase superfamily
SanJ4211_0399	COG0450	alkyl hydroperoxide reductase
SanJ4211_0400	COG3634	alkyl hydroperoxide reductase activity
SanJ4211_0401c	COG1854	S-ribosylhomocysteine lyase activity
SanJ4211_0402	COG1418	mRNA catabolic process
SanJ4211_0403	COG0194	GDP metabolic process
SanJ4211_0404	COG1758	RNA polymerase activity
SanJ4211_0405	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SanJ4211_0406	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SanJ4211_0407	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SanJ4211_0407	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SanJ4211_0408	COG0631	protein serine/threonine phosphatase activity
SanJ4211_0409	COG2815	serine threonine protein kinase
SanJ4211_0409	COG0515	serine threonine protein kinase
SanJ4211_0414	COG1185	polyribonucleotide nucleotidyltransferase activity
SanJ4211_0416c	COG3557	Belongs to the UPF0374 family
SanJ4211_0417c	COG2137	regulation of response to DNA damage stimulus
SanJ4211_0419	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SanJ4211_0421c	COG2070	2-Nitropropane dioxygenase
SanJ4211_0425	COG0519	Catalyzes the synthesis of GMP from XMP
SanJ4211_0427	COG0525	valine-tRNA ligase activity
SanJ4211_0429c	COG1739	Uncharacterized protein family UPF0029
SanJ4211_0430	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SanJ4211_0431	COG1040	competence protein
SanJ4211_0433	COG0742	ribosomal rna small subunit methyltransferase
SanJ4211_0434	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SanJ4211_0435	COG3480	Lon protease (S16) C-terminal proteolytic domain
SanJ4211_0436	COG4470	Protein conserved in bacteria
SanJ4211_0437	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SanJ4211_0439	COG0133	tryptophan synthase activity
SanJ4211_0444c	COG1187	pseudouridine synthase activity
SanJ4211_0447	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SanJ4211_0448	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SanJ4211_0449	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SanJ4211_0451	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SanJ4211_0452	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SanJ4211_0453	COG1799	cell septum assembly
SanJ4211_0456	COG3599	regulation of cell shape
SanJ4211_0457	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SanJ4211_0458c	COG1846	Transcriptional regulator
SanJ4211_0461	COG0628	permease
SanJ4211_0463	COG1253	flavin adenine dinucleotide binding
SanJ4211_0464c	COG2188	Transcriptional regulator
SanJ4211_0465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SanJ4211_0465	COG1263	PTS System
SanJ4211_0466	COG1263	PTS System
SanJ4211_0466	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SanJ4211_0467	COG2190	(PTS) system
SanJ4211_0467	COG1263	PTS System
SanJ4211_0467	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SanJ4211_0468	COG0366	Alpha amylase catalytic
SanJ4211_0470	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SanJ4211_0471	COG1227	inorganic diphosphatase activity
SanJ4211_0475c	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SanJ4211_0476	COG2244	polysaccharide biosynthetic process
SanJ4211_0477	COG0626	cystathionine gamma-synthase activity
SanJ4211_0478	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SanJ4211_0479	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SanJ4211_0480	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SanJ4211_0481	COG0740	serine-type endopeptidase activity
SanJ4211_0482	COG4471	UPF0298 protein
SanJ4211_0485	COG0559	Belongs to the binding-protein-dependent transport system permease family
SanJ4211_0487	COG0411	ABC transporter
SanJ4211_0488	COG0410	ABC transporter
SanJ4211_0489	COG0517	IMP dehydrogenase activity
SanJ4211_0490c	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SanJ4211_0491	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SanJ4211_0492	COG0470	DNA polymerase III
SanJ4211_0493	COG4467	Involved in initiation control of chromosome replication
SanJ4211_0495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SanJ4211_0496	COG1393	Belongs to the ArsC family
SanJ4211_0497	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SanJ4211_0498c	COG0708	Exodeoxyribonuclease III
SanJ4211_0499	COG0640	Transcriptional regulator
SanJ4211_0504	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SanJ4211_0504	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SanJ4211_0506	COG0745	RESPONSE REGULATOR receiver
SanJ4211_0507	COG0642	Histidine kinase
SanJ4211_0510	COG1136	(ABC) transporter
SanJ4211_0511	COG0577	efflux transmembrane transporter activity
SanJ4211_0516	COG1136	(ABC) transporter
SanJ4211_0517	COG0577	efflux transmembrane transporter activity
SanJ4211_0518	COG0531	amino acid
SanJ4211_0519	COG0456	acetyltransferase
SanJ4211_0525	COG1028	Short-chain dehydrogenase reductase Sdr
SanJ4211_0528	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SanJ4211_0531	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SanJ4211_0533	COG0488	(ABC) transporter
SanJ4211_0536	COG1983	PspC domain protein
SanJ4211_0537	COG1674	ftsk spoiiie
SanJ4211_0537	COG0697	spore germination
SanJ4211_0538	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SanJ4211_0541	COG0081	regulation of translation
SanJ4211_0542	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SanJ4211_0543	COG0372	Belongs to the citrate synthase family
SanJ4211_0544	COG0538	isocitrate dehydrogenase activity
SanJ4211_0545	COG0528	UMP kinase activity
SanJ4211_0546	COG0233	cytoplasmic translational termination
SanJ4211_0547	COG2996	Protein conserved in bacteria
SanJ4211_0549	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SanJ4211_0551	COG2274	protein secretion by the type I secretion system
SanJ4211_0552	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SanJ4211_0554c	COG3290	protein histidine kinase activity
SanJ4211_0566	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SanJ4211_0567	COG0549	Belongs to the carbamate kinase family
SanJ4211_0568	COG1288	antiporter activity
SanJ4211_0569	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SanJ4211_0570c	COG2801	Transposase and inactivated derivatives
SanJ4211_0572c	COG1438	arginine binding
SanJ4211_0573c	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SanJ4211_0574	COG0363	glucosamine-6-phosphate deaminase activity
SanJ4211_0578	COG2723	6-phospho-beta-galactosidase activity
SanJ4211_0580	COG4095	Psort location CytoplasmicMembrane, score
SanJ4211_0582	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SanJ4211_0582	COG3711	transcriptional antiterminator
SanJ4211_0583	COG1447	Phosphotransferase system cellobiose-specific component IIA
SanJ4211_0585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SanJ4211_0589	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SanJ4211_0591	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SanJ4211_0593	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SanJ4211_0596c	COG2348	transferase activity, transferring amino-acyl groups
SanJ4211_0597c	COG2348	transferase activity, transferring amino-acyl groups
SanJ4211_0599c	COG1078	dGTPase activity
SanJ4211_0607	COG0561	phosphatase activity
SanJ4211_0608	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SanJ4211_0609	COG2884	Cell division ATP-binding protein ftsE
SanJ4211_0610	COG2177	Part of the ABC transporter FtsEX involved in
SanJ4211_0612	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SanJ4211_0612	COG1199	ATP-dependent helicase activity
SanJ4211_0614	COG0772	Belongs to the SEDS family
SanJ4211_0617	COG0187	DNA topoisomerase II activity
SanJ4211_0618	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
SanJ4211_0622c	COG2706	6-phosphogluconolactonase activity
SanJ4211_0623	COG0745	RESPONSE REGULATOR receiver
SanJ4211_0624	COG5002	protein histidine kinase activity
SanJ4211_0624	COG3850	Histidine kinase
SanJ4211_0625	COG0628	permease
SanJ4211_0627	COG0028	Belongs to the TPP enzyme family
SanJ4211_0628	COG3527	Alpha-acetolactate decarboxylase
SanJ4211_0632	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SanJ4211_0634	COG4443	Transcriptional Coactivator p15 (PC4)
SanJ4211_0635	COG4152	abc transporter atp-binding protein
SanJ4211_0636	COG1668	transmembrane transport
SanJ4211_0637	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
SanJ4211_0638	COG1074	ATP-dependent DNA helicase activity
SanJ4211_0639	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SanJ4211_0640	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SanJ4211_0641	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SanJ4211_0642	COG0297	glycogen (starch) synthase activity
SanJ4211_0643	COG0058	SHG alpha-glucan phosphorylase activity
SanJ4211_0645	COG0356	it plays a direct role in the translocation of protons across the membrane
SanJ4211_0646	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SanJ4211_0647	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SanJ4211_0648	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SanJ4211_0649	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SanJ4211_0651	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SanJ4211_0653	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SanJ4211_0657	COG1132	(ABC) transporter
SanJ4211_0660	COG1346	cytolysis
SanJ4211_0661	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SanJ4211_0662	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
SanJ4211_0664	COG2384	SAM-dependent methyltransferase
SanJ4211_0665	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SanJ4211_0666	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SanJ4211_0669	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SanJ4211_0671	COG1088	dTDP-glucose 4,6-dehydratase activity
SanJ4211_0672	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SanJ4211_0674	COG0463	Glycosyl transferase, family 2
SanJ4211_0679	COG0463	Glycosyl transferase, family 2
SanJ4211_0680	COG1091	dTDP-4-dehydrorhamnose reductase activity
SanJ4211_0689	COG1368	sulfuric ester hydrolase activity
SanJ4211_0690c	COG0006	proline dipeptidase activity
SanJ4211_0691	COG1609	Transcriptional regulator
SanJ4211_0693	COG0438	transferase activity, transferring glycosyl groups
SanJ4211_0695	COG0745	RESPONSE REGULATOR receiver
SanJ4211_0696	COG5002	protein histidine kinase activity
SanJ4211_0697	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SanJ4211_0700	COG0571	ribonuclease III activity
SanJ4211_0701	COG1196	nuclear chromosome segregation
SanJ4211_0702	COG0561	phosphatase activity
SanJ4211_0703	COG0561	phosphatase activity
SanJ4211_0704	COG0552	protein localization to endoplasmic reticulum
SanJ4211_0705c	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SanJ4211_0706c	COG0477	Major facilitator Superfamily
SanJ4211_0707c	COG3689	TIGRFAM TIGR03943 family protein
SanJ4211_0708c	COG0701	Predicted permease
SanJ4211_0710	COG2183	response to ionizing radiation
SanJ4211_0711	COG3091	SprT-like family
SanJ4211_0713	COG0494	nUDIX hydrolase
SanJ4211_0714	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
SanJ4211_0715	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SanJ4211_0725	COG0488	(ABC) transporter
SanJ4211_0728c	COG3442	glutamine amidotransferase
SanJ4211_0729c	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SanJ4211_0730	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SanJ4211_0732	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SanJ4211_0733	COG0560	Phosphoserine phosphatase
SanJ4211_0738	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SanJ4211_0739	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SanJ4211_0740	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SanJ4211_0742	COG0346	lactoylglutathione lyase activity
SanJ4211_0743	COG0726	polysaccharide deacetylase
SanJ4211_0745c	COG0673	inositol 2-dehydrogenase activity
SanJ4211_0746	COG0572	uridine kinase
SanJ4211_0748c	COG2195	Cleaves the N-terminal amino acid of tripeptides
SanJ4211_0749c	COG0561	phosphatase activity
SanJ4211_0750	COG0481	GTPase activity
SanJ4211_0752	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SanJ4211_0753	COG3842	ATPase activity
SanJ4211_0754	COG1176	ABC-type spermidine putrescine transport system, permease component I
SanJ4211_0755	COG1177	transmembrane transport
SanJ4211_0756	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SanJ4211_0759c	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SanJ4211_0759c	COG0574	Belongs to the PEP-utilizing enzyme family
SanJ4211_0760	COG0517	IMP dehydrogenase activity
SanJ4211_0761	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
SanJ4211_0762	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
SanJ4211_0763	COG1104	cysteine desulfurase activity
SanJ4211_0764	COG0301	tRNA thio-modification
SanJ4211_0765	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SanJ4211_0767	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SanJ4211_0768	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SanJ4211_0768	COG3064	Membrane
SanJ4211_0769	COG0425	Belongs to the sulfur carrier protein TusA family
SanJ4211_0769	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SanJ4211_0770	COG0446	pyridine nucleotide-disulphide oxidoreductase
SanJ4211_0773c	COG1937	Protein conserved in bacteria
SanJ4211_0776	COG0583	DNA-binding transcription factor activity
SanJ4211_0778	COG0564	pseudouridine synthase activity
SanJ4211_0781	COG2824	Alkylphosphonate utilization operon protein PhnA
SanJ4211_0785	COG0038	chloride channel
SanJ4211_0786	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
SanJ4211_0787	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SanJ4211_0790	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SanJ4211_0791	COG1388	LysM domain
SanJ4211_0791	COG1705	Flagellar rod assembly protein muramidase FlgJ
SanJ4211_0792	COG1132	(ABC) transporter
SanJ4211_0793	COG1132	(ABC) transporter
SanJ4211_0794c	COG0488	(ABC) transporter
SanJ4211_0798	COG0556	nucleotide-excision repair
SanJ4211_0801	COG1131	(ABC) transporter
SanJ4211_0803	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SanJ4211_0805	COG0647	UMP catabolic process
SanJ4211_0809	COG1660	Displays ATPase and GTPase activities
SanJ4211_0810	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SanJ4211_0811	COG1481	regulation of sporulation
SanJ4211_0812	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SanJ4211_0814	COG0540	Belongs to the ATCase OTCase family
SanJ4211_0815	COG0505	Belongs to the CarA family
SanJ4211_0816	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SanJ4211_0817	COG2814	Major facilitator Superfamily
SanJ4211_0818	COG0583	DNA-binding transcription factor activity
SanJ4211_0825	COG0543	2 iron, 2 sulfur cluster binding
SanJ4211_0826	COG0167	dihydroorotate dehydrogenase activity
SanJ4211_0828	COG0284	orotidine-5'-phosphate decarboxylase activity
SanJ4211_0830	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SanJ4211_0833	COG4479	Belongs to the UPF0346 family
SanJ4211_0834	COG1702	phosphate starvation-inducible protein PhoH
SanJ4211_0837c	COG0686	Belongs to the AlaDH PNT family
SanJ4211_0843	COG1132	(ABC) transporter
SanJ4211_0844	COG1132	(ABC) transporter
SanJ4211_0845	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SanJ4211_0846	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SanJ4211_0847	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SanJ4211_0853	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SanJ4211_0854	COG0237	dephospho-CoA kinase activity
SanJ4211_0855	COG2814	Major facilitator Superfamily
SanJ4211_0857	COG0557	exoribonuclease II activity
SanJ4211_0858	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SanJ4211_0859c	COG2801	Transposase and inactivated derivatives
SanJ4211_0861	COG1555	photosystem II stabilization
SanJ4211_0862	COG0658	competence protein
SanJ4211_0862	COG2333	competence protein COMEC
SanJ4211_0866	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SanJ4211_0867	COG1051	belongs to the nudix hydrolase family
SanJ4211_0868	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SanJ4211_0869	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SanJ4211_0870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SanJ4211_0872	COG4109	DRTGG domain
SanJ4211_0873	COG0024	Methionine aminopeptidase
SanJ4211_0875	COG1846	Transcriptional regulator
SanJ4211_0877c	COG2246	polysaccharide biosynthetic process
SanJ4211_0878	COG4708	membrane
SanJ4211_0879c	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SanJ4211_0880	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SanJ4211_0881	COG1597	lipid kinase activity
SanJ4211_0882	COG1523	belongs to the glycosyl hydrolase 13 family
SanJ4211_0883	COG0228	four-way junction DNA binding
SanJ4211_0884	COG1837	Belongs to the UPF0109 family
SanJ4211_0885c	COG2801	Transposase and inactivated derivatives
SanJ4211_0886c	COG1827	regulation of RNA biosynthetic process
SanJ4211_0889	COG3142	Participates in the control of copper homeostasis
SanJ4211_0890	COG2315	Protein conserved in bacteria
SanJ4211_0891	COG1132	(ABC) transporter
SanJ4211_0892	COG1132	(ABC) transporter
SanJ4211_0893c	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SanJ4211_0895	COG1518	maintenance of DNA repeat elements
SanJ4211_0900	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SanJ4211_0901c	COG1970	mechanosensitive ion channel activity
SanJ4211_0902	COG0358	DNA primase activity
SanJ4211_0903	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SanJ4211_0904	COG2151	metal-sulfur cluster biosynthetic enzyme
SanJ4211_0905	COG1114	Component of the transport system for branched-chain amino acids
SanJ4211_0906	COG0785	Cytochrome C biogenesis protein
SanJ4211_0907	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SanJ4211_0908	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SanJ4211_0908	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SanJ4211_0909	COG2197	response regulator
SanJ4211_0910	COG2972	Histidine kinase
SanJ4211_0913c	COG4555	ABC transporter
SanJ4211_0914c	COG0431	NADPH-dependent FMN reductase
SanJ4211_0914c	COG1053	succinate dehydrogenase
SanJ4211_0914c	COG3976	FMN-binding domain protein
SanJ4211_0918c	COG2205	protein histidine kinase activity
SanJ4211_0919c	COG0745	RESPONSE REGULATOR receiver
SanJ4211_0924	COG0516	GMP reductase activity
SanJ4211_0925	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SanJ4211_0926	COG2233	PERMEase
SanJ4211_0927	COG0534	Mate efflux family protein
SanJ4211_0928c	COG1942	4-Oxalocrotonate Tautomerase
SanJ4211_0929	COG1435	thymidine kinase activity
SanJ4211_0930	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SanJ4211_0931	COG2890	protein-(glutamine-N5) methyltransferase activity
SanJ4211_0933	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SanJ4211_0935	COG0741	lytic transglycosylase activity
SanJ4211_0937c	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SanJ4211_0937c	COG0519	Catalyzes the synthesis of GMP from XMP
SanJ4211_0940	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SanJ4211_0941	COG4974	Belongs to the 'phage' integrase family
SanJ4211_0942c	COG1028	Short-chain dehydrogenase reductase Sdr
SanJ4211_0944c	COG0095	Lipoate-protein ligase
SanJ4211_0945c	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SanJ4211_0946c	COG0508	dehydrogenase complex catalyzes the overall conversion of
SanJ4211_0947c	COG0022	dehydrogenase e1 component
SanJ4211_0948c	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SanJ4211_0952c	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SanJ4211_0953c	COG0135	phosphoribosylanthranilate isomerase activity
SanJ4211_0954c	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SanJ4211_0955c	COG0758	DNA mediated transformation
SanJ4211_0956c	COG0110	maltose O-acetyltransferase activity
SanJ4211_0957c	COG3711	transcriptional antiterminator
SanJ4211_0959c	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SanJ4211_0960c	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SanJ4211_0961c	COG1960	acyl-CoA dehydrogenase activity
SanJ4211_0962c	COG0583	DNA-binding transcription factor activity
SanJ4211_0963c	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SanJ4211_0965c	COG1024	Enoyl-CoA hydratase
SanJ4211_0966c	COG0183	Belongs to the thiolase family
SanJ4211_0967c	COG1250	3-hydroxyacyl-CoA dehydrogenase
SanJ4211_0968c	COG1960	acyl-CoA dehydrogenase activity
SanJ4211_0969	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SanJ4211_0970c	COG3764	Sortase (surface protein transpeptidase)
SanJ4211_0971c	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SanJ4211_0972	COG0039	L-malate dehydrogenase activity
SanJ4211_0974c	COG0539	negative regulation of cytoplasmic translation
SanJ4211_0976c	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SanJ4211_0977c	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SanJ4211_0981c	COG0187	DNA topoisomerase II activity
SanJ4211_0982	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SanJ4211_0983c	COG0737	Belongs to the 5'-nucleotidase family
SanJ4211_0984c	COG2976	Protein conserved in bacteria
SanJ4211_0985c	COG2131	deaminase
SanJ4211_0986c	COG1309	transcriptional regulator
SanJ4211_0995c	COG2814	Major facilitator Superfamily
SanJ4211_0996c	COG0017	Asparaginyl-tRNA synthetase
SanJ4211_0998c	COG0436	Aminotransferase
SanJ4211_1000	COG1846	Transcriptional regulator
SanJ4211_1002c	COG3022	response to hydroperoxide
SanJ4211_1004	COG1272	protein, Hemolysin III
SanJ4211_1008c	COG1744	ABC transporter substrate-binding protein PnrA-like
SanJ4211_1009c	COG0295	cytidine deaminase activity
SanJ4211_1010c	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SanJ4211_1012c	COG2813	Specifically methylates the guanine in position
SanJ4211_1013	COG1072	(Pantothenic acid kinase))
SanJ4211_1016c	COG4187	Peptidase family M20/M25/M40
SanJ4211_1019c	COG5002	protein histidine kinase activity
SanJ4211_1020c	COG0745	RESPONSE REGULATOR receiver
SanJ4211_1031	COG1674	ftsk spoiiie
SanJ4211_1037c	COG1940	carbohydrate kinase activity
SanJ4211_1038	COG0583	DNA-binding transcription factor activity
SanJ4211_1040c	COG0656	L-ascorbic acid biosynthetic process
SanJ4211_1045c	COG0083	homoserine kinase activity
SanJ4211_1047	COG0726	polysaccharide deacetylase
SanJ4211_1049c	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SanJ4211_1051c	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SanJ4211_1052c	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SanJ4211_1053	COG1609	Transcriptional regulator
SanJ4211_1054	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SanJ4211_1054	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SanJ4211_1057c	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SanJ4211_1058c	COG1956	GAF domain-containing protein
SanJ4211_1062c	COG3443	Belongs to the bacterial solute-binding protein 9 family
SanJ4211_1062c	COG0803	Belongs to the bacterial solute-binding protein 9 family
SanJ4211_1063c	COG0336	Belongs to the RNA methyltransferase TrmD family
SanJ4211_1064c	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SanJ4211_1069c	COG4974	Belongs to the 'phage' integrase family
SanJ4211_1077c	COG0222	ribosome binding
SanJ4211_1078c	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SanJ4211_1079c	COG3708	Transcriptional regulator
SanJ4211_1079c	COG2207	Transcriptional regulator
SanJ4211_1081c	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SanJ4211_1082c	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SanJ4211_1085c	COG1247	-acetyltransferase
SanJ4211_1086c	COG2759	Belongs to the formate--tetrahydrofolate ligase family
SanJ4211_1088	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SanJ4211_1089	COG4684	Psort location CytoplasmicMembrane, score
SanJ4211_1090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SanJ4211_1093c	COG0280	phosphate acetyltransferase
SanJ4211_1094c	COG0564	pseudouridine synthase activity
SanJ4211_1095c	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SanJ4211_1096c	COG2357	RelA SpoT domain protein
SanJ4211_1098	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SanJ4211_1099	COG1104	cysteine desulfurase activity
SanJ4211_1101	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SanJ4211_1102	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SanJ4211_1103c	COG2003	Belongs to the UPF0758 family
SanJ4211_1105c	COG0704	Plays a role in the regulation of phosphate uptake
SanJ4211_1106c	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SanJ4211_1107c	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SanJ4211_1108c	COG0581	inorganic phosphate transmembrane transporter activity
SanJ4211_1109c	COG0573	inorganic phosphate transmembrane transporter activity
SanJ4211_1110c	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SanJ4211_1111c	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SanJ4211_1111c	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SanJ4211_1112c	COG0483	inositol monophosphate 1-phosphatase activity
SanJ4211_1113c	COG4476	Belongs to the UPF0223 family
SanJ4211_1114c	COG1393	Belongs to the ArsC family
SanJ4211_1115c	COG0196	riboflavin kinase activity
SanJ4211_1116c	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SanJ4211_1119c	COG1132	(ABC) transporter
SanJ4211_1121c	COG2378	regulation of single-species biofilm formation
SanJ4211_1123c	COG0210	DNA helicase
SanJ4211_1124	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SanJ4211_1126c	COG1126	abc transporter atp-binding protein
SanJ4211_1127c	COG0765	amino acid transport
SanJ4211_1129c	COG0469	pyruvate kinase activity
SanJ4211_1130c	COG0205	6-phosphofructokinase activity
SanJ4211_1132	COG1725	Transcriptional regulator
SanJ4211_1133	COG1131	(ABC) transporter
SanJ4211_1135c	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SanJ4211_1135c	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SanJ4211_1138c	COG0300	oxidoreductase activity
SanJ4211_1142c	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SanJ4211_1143c	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SanJ4211_1145c	COG0577	efflux transmembrane transporter activity
SanJ4211_1146c	COG1136	(ABC) transporter
SanJ4211_1148	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SanJ4211_1149	COG1268	BioY protein
SanJ4211_1152c	COG1011	Hydrolase
SanJ4211_1158c	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SanJ4211_1158c	COG0072	phenylalanine-tRNA ligase activity
SanJ4211_1161c	COG0488	(ABC) transporter
SanJ4211_1162c	COG0617	tRNA 3'-terminal CCA addition
SanJ4211_1163c	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SanJ4211_1164c	COG1307	EDD domain protein, DegV family
SanJ4211_1166c	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SanJ4211_1166c	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SanJ4211_1166c	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SanJ4211_1167c	COG1105	Belongs to the carbohydrate kinase PfkB family
SanJ4211_1168c	COG1349	DNA-binding transcription factor activity
SanJ4211_1170	COG0492	ferredoxin-NADP+ reductase activity
SanJ4211_1171c	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SanJ4211_1179	COG2801	Transposase and inactivated derivatives
SanJ4211_1182c	COG1396	sequence-specific DNA binding
SanJ4211_1184c	COG2723	6-phospho-beta-galactosidase activity
SanJ4211_1187c	COG3711	transcriptional antiterminator
SanJ4211_1188c	COG3684	Belongs to the aldolase LacD family
SanJ4211_1189c	COG1105	Belongs to the carbohydrate kinase PfkB family
SanJ4211_1190c	COG0698	ribose 5-phosphate isomerase
SanJ4211_1191c	COG0698	ribose 5-phosphate isomerase
SanJ4211_1192c	COG1349	DNA-binding transcription factor activity
SanJ4211_1196c	COG0542	response to heat
SanJ4211_1198c	COG0542	response to heat
SanJ4211_1199c	COG1396	sequence-specific DNA binding
SanJ4211_1224c	COG0270	DNA (cytosine-5-)-methyltransferase activity
SanJ4211_1228c	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SanJ4211_1229c	COG1316	TRANSCRIPTIONal
SanJ4211_1230c	COG0077	Prephenate dehydratase
SanJ4211_1231c	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SanJ4211_1232c	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SanJ4211_1235c	COG3679	Belongs to the UPF0342 family
SanJ4211_1236c	COG0287	Prephenate dehydrogenase
SanJ4211_1238c	COG0730	response to heat
SanJ4211_1239c	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SanJ4211_1240c	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SanJ4211_1241c	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SanJ4211_1242c	COG0710	3-dehydroquinate dehydratase activity
SanJ4211_1243c	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SanJ4211_1244	COG1368	sulfuric ester hydrolase activity
SanJ4211_1246c	COG0813	purine-nucleoside phosphorylase activity
SanJ4211_1248c	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SanJ4211_1249	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SanJ4211_1254c	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SanJ4211_1256c	COG1595	DNA-templated transcription, initiation
SanJ4211_1257c	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SanJ4211_1258c	COG0772	Belongs to the SEDS family
SanJ4211_1261	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SanJ4211_1262	COG0406	alpha-ribazole phosphatase activity
SanJ4211_1263	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SanJ4211_1269c	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SanJ4211_1271c	COG1447	Phosphotransferase system cellobiose-specific component IIA
SanJ4211_1273c	COG1349	DNA-binding transcription factor activity
SanJ4211_1275	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SanJ4211_1276c	COG1959	2 iron, 2 sulfur cluster binding
SanJ4211_1279c	COG1136	(ABC) transporter
SanJ4211_1284c	COG0716	FMN binding
SanJ4211_1285	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SanJ4211_1286	COG0254	rRNA binding
SanJ4211_1290c	COG1125	glycine betaine transport
SanJ4211_1291c	COG1732	Glycine betaine
SanJ4211_1293c	COG1573	uracil-dna glycosylase
SanJ4211_1295c	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SanJ4211_1297c	COG0322	excinuclease ABC activity
SanJ4211_1298c	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SanJ4211_1300	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SanJ4211_1302	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SanJ4211_1306c	COG1476	TRANSCRIPTIONal
SanJ4211_1309c	COG0204	Acyl-transferase
SanJ4211_1310	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SanJ4211_1311	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SanJ4211_1312	COG2827	Endonuclease containing a URI domain
SanJ4211_1313c	COG3867	Arabinogalactan endo-beta-1,4-galactanase
SanJ4211_1314c	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SanJ4211_1314c	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SanJ4211_1315c	COG1447	Phosphotransferase system cellobiose-specific component IIA
SanJ4211_1316c	COG2723	6-phospho-beta-galactosidase activity
SanJ4211_1317c	COG3711	transcriptional antiterminator
SanJ4211_1318c	COG1755	Isoprenylcysteine carboxyl methyltransferase
SanJ4211_1320c	COG3775	system Galactitol-specific IIC component
SanJ4211_1324	COG0698	ribose 5-phosphate isomerase
SanJ4211_1325c	COG1349	DNA-binding transcription factor activity
SanJ4211_1326	COG3684	Belongs to the aldolase LacD family
SanJ4211_1327c	COG0513	Belongs to the DEAD box helicase family
SanJ4211_1331c	COG3620	sequence-specific DNA binding
SanJ4211_1335c	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SanJ4211_1336c	COG1181	Belongs to the D-alanine--D-alanine ligase family
SanJ4211_1337c	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SanJ4211_1338c	COG0768	penicillin binding
SanJ4211_1341c	COG3620	sequence-specific DNA binding
SanJ4211_1342c	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
SanJ4211_1345c	COG0588	phosphoglycerate mutase activity
SanJ4211_1347c	COG1388	LysM domain
SanJ4211_1347c	COG3942	CHAP domain
SanJ4211_1398	COG0582	viral genome integration into host DNA
SanJ4211_1400c	COG1307	EDD domain protein, DegV family
SanJ4211_1402	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SanJ4211_1403	COG4605	iron ion homeostasis
SanJ4211_1404	COG4604	ABC transporter, ATP-binding protein
SanJ4211_1405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SanJ4211_1406c	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SanJ4211_1407c	COG0497	DNA recombination
SanJ4211_1408c	COG1438	arginine binding
SanJ4211_1409c	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SanJ4211_1411c	COG1722	exodeoxyribonuclease VII activity
SanJ4211_1412c	COG1570	exodeoxyribonuclease VII activity
SanJ4211_1415c	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SanJ4211_1416c	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SanJ4211_1417	COG0577	efflux transmembrane transporter activity
SanJ4211_1418	COG1136	(ABC) transporter
SanJ4211_1424c	COG4703	Protein of unknown function (DUF1797)
SanJ4211_1425	COG0542	response to heat
SanJ4211_1428	COG0494	nUDIX hydrolase
SanJ4211_1430c	COG0025	NhaP-type Na H and K H
SanJ4211_1432c	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SanJ4211_1433c	COG1242	4 iron, 4 sulfur cluster binding
SanJ4211_1435c	COG0671	phosphoesterase, PA-phosphatase related
SanJ4211_1436c	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SanJ4211_1438	COG0569	domain protein
SanJ4211_1439	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SanJ4211_1443c	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SanJ4211_1444c	COG1187	pseudouridine synthase activity
SanJ4211_1445c	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SanJ4211_1446c	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SanJ4211_1447c	COG4974	Belongs to the 'phage' integrase family
SanJ4211_1450c	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SanJ4211_1451c	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SanJ4211_1452c	COG3763	UPF0154 protein
SanJ4211_1456c	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SanJ4211_1457	COG1254	Belongs to the acylphosphatase family
SanJ4211_1458	COG0706	membrane insertase activity
SanJ4211_1460c	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SanJ4211_1462c	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SanJ4211_1465c	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SanJ4211_1467c	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SanJ4211_1469c	COG1160	GTP binding
SanJ4211_1472c	COG1484	DNA-dependent DNA replication
SanJ4211_1474c	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SanJ4211_1477c	COG1263	PTS System
SanJ4211_1477c	COG2190	(PTS) system
SanJ4211_1477c	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SanJ4211_1479c	COG0745	RESPONSE REGULATOR receiver
SanJ4211_1480c	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SanJ4211_1486c	COG0501	Belongs to the peptidase M48B family
SanJ4211_1487c	COG1704	LemA family
SanJ4211_1488	COG0357	Ribosomal RNA small subunit methyltransferase G
SanJ4211_1489c	COG1442	glycosyl transferase family 8
SanJ4211_1490c	COG4221	oxidoreductase activity
SanJ4211_1492c	COG1122	ATPase activity
SanJ4211_1494c	COG4720	Psort location CytoplasmicMembrane, score
SanJ4211_1497c	COG2801	Transposase and inactivated derivatives
SanJ4211_1499c	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SanJ4211_1500c	COG1464	Belongs to the NlpA lipoprotein family
SanJ4211_1501c	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SanJ4211_1504c	COG0659	secondary active sulfate transmembrane transporter activity
SanJ4211_1505c	COG1396	sequence-specific DNA binding
SanJ4211_1506c	COG0217	transcriptional regulatory protein
SanJ4211_1507c	COG1323	Belongs to the UPF0348 family
SanJ4211_1509c	COG2226	methyltransferase
SanJ4211_1510c	COG0799	negative regulation of ribosome biogenesis
SanJ4211_1511c	COG1713	HD superfamily hydrolase involved in NAD metabolism
SanJ4211_1512c	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SanJ4211_1513c	COG1534	Rna-binding protein
SanJ4211_1514c	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SanJ4211_1515c	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SanJ4211_1518c	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SanJ4211_1519c	COG0154	amidase activity
SanJ4211_1520c	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SanJ4211_1521c	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SanJ4211_1522c	COG1335	isochorismatase
SanJ4211_1523c	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SanJ4211_1524c	COG0436	Aminotransferase
SanJ4211_1525	COG0589	response to stress
SanJ4211_1526c	COG0561	phosphatase activity
SanJ4211_1527	COG0252	asparaginase activity
SanJ4211_1528c	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SanJ4211_1529c	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SanJ4211_1530c	COG0736	holo-[acyl-carrier-protein] synthase activity
SanJ4211_1531c	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SanJ4211_1533c	COG0531	amino acid
SanJ4211_1534c	COG1482	cell wall glycoprotein biosynthetic process
SanJ4211_1535c	COG2188	Transcriptional regulator
SanJ4211_1536c	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SanJ4211_1537	COG2723	6-phospho-beta-galactosidase activity
SanJ4211_1538c	COG1447	Phosphotransferase system cellobiose-specific component IIA
SanJ4211_1539c	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SanJ4211_1540c	COG1132	(ABC) transporter
SanJ4211_1543c	COG0242	peptide deformylase activity
SanJ4211_1544c	COG1940	carbohydrate kinase activity
SanJ4211_1545c	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SanJ4211_1545c	COG1263	PTS System
SanJ4211_1545c	COG2190	(PTS) system
SanJ4211_1546	COG1621	beta-fructofuranosidase activity
SanJ4211_1547	COG1609	Transcriptional regulator
SanJ4211_1548c	COG0561	phosphatase activity
SanJ4211_1549c	COG4608	Belongs to the ABC transporter superfamily
SanJ4211_1550c	COG0444	Belongs to the ABC transporter superfamily
SanJ4211_1551c	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SanJ4211_1552c	COG0601	transmembrane transport
SanJ4211_1553c	COG4166	transmembrane transport
SanJ4211_1554c	COG4166	transmembrane transport
SanJ4211_1556c	COG0504	CTP synthase activity
SanJ4211_1557c	COG3343	RNA polymerase activity
SanJ4211_1558c	COG0544	peptidyl-prolyl cis-trans isomerase activity
SanJ4211_1560c	COG4720	Psort location CytoplasmicMembrane, score
SanJ4211_1561c	COG0351	phosphomethylpyrimidine kinase
SanJ4211_1562c	COG0101	tRNA pseudouridine synthase activity
SanJ4211_1564c	COG0484	heat shock protein binding
SanJ4211_1566c	COG0443	Heat shock 70 kDa protein
SanJ4211_1567c	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SanJ4211_1568c	COG1420	regulation of RNA biosynthetic process
SanJ4211_1569c	COG0588	phosphoglycerate mutase activity
SanJ4211_1570c	COG0588	phosphoglycerate mutase activity
SanJ4211_1571c	COG2848	UPF0210 protein
SanJ4211_1572c	COG3830	Belongs to the UPF0237 family
SanJ4211_1574c	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
SanJ4211_1575c	COG1215	transferase activity, transferring glycosyl groups
SanJ4211_1577c	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SanJ4211_1590	COG4974	Belongs to the 'phage' integrase family
SanJ4211_1591c	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SanJ4211_1592c	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SanJ4211_1594c	COG3688	RNA-binding protein containing a PIN domain
SanJ4211_1596c	COG3842	ATPase activity
SanJ4211_1598c	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SanJ4211_1599c	COG0215	cysteine-tRNA ligase activity
SanJ4211_1600c	COG1045	serine acetyltransferase
SanJ4211_1601c	COG1185	polyribonucleotide nucleotidyltransferase activity
SanJ4211_1602	COG1164	Oligoendopeptidase f
SanJ4211_1605c	COG3118	belongs to the thioredoxin family
SanJ4211_1607c	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SanJ4211_1608c	COG1187	pseudouridine synthase activity
SanJ4211_1617c	COG2176	DNA-directed DNA polymerase activity
SanJ4211_1619c	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SanJ4211_1620c	COG1523	belongs to the glycosyl hydrolase 13 family
SanJ4211_1623c	COG2249	NAD(P)H dehydrogenase (quinone) activity
SanJ4211_1626c	COG1609	Transcriptional regulator
SanJ4211_1627c	COG0561	phosphatase activity
SanJ4211_1629c	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SanJ4211_1631c	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SanJ4211_1632c	COG0006	proline dipeptidase activity
SanJ4211_1634c	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SanJ4211_1637c	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SanJ4211_1638c	COG0629	single-stranded DNA binding
SanJ4211_1645c	COG2723	6-phospho-beta-galactosidase activity
SanJ4211_1646c	COG2723	6-phospho-beta-galactosidase activity
SanJ4211_1648c	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SanJ4211_1650	COG1122	ATPase activity
SanJ4211_1655c	COG5002	protein histidine kinase activity
SanJ4211_1656c	COG0745	RESPONSE REGULATOR receiver
SanJ4211_1657c	COG2723	6-phospho-beta-galactosidase activity
SanJ4211_1658c	COG1304	FMN binding
SanJ4211_1659c	COG0028	Belongs to the TPP enzyme family
SanJ4211_1660c	COG1876	peptidase activity
SanJ4211_1665c	COG0561	phosphatase activity
SanJ4211_1667c	COG0346	lactoylglutathione lyase activity
SanJ4211_1672c	COG1263	PTS System
SanJ4211_1672c	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SanJ4211_1672c	COG2190	(PTS) system
SanJ4211_1677	COG2746	aminoglycoside 3-N-acetyltransferase activity
SanJ4211_1681c	COG1447	Phosphotransferase system cellobiose-specific component IIA
SanJ4211_1682c	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SanJ4211_1684c	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SanJ4211_1685	COG1940	carbohydrate kinase activity
SanJ4211_1687c	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SanJ4211_1687c	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SanJ4211_1688c	COG0167	dihydroorotate dehydrogenase activity
SanJ4211_1689	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SanJ4211_1691c	COG0668	transmembrane transport
SanJ4211_1692	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
SanJ4211_1693c	COG3118	belongs to the thioredoxin family
SanJ4211_1695c	COG1193	negative regulation of DNA recombination
SanJ4211_1699	COG0681	Belongs to the peptidase S26 family
SanJ4211_1701	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SanJ4211_1703c	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SanJ4211_1704	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SanJ4211_1705	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SanJ4211_1710c	COG1214	PFAM Peptidase M22, glycoprotease
SanJ4211_1714c	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SanJ4211_1715c	COG0049	tRNA binding
SanJ4211_1716c	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SanJ4211_1718c	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SanJ4211_1719c	COG3481	metal-dependent phosphohydrolase, HD sub domain
SanJ4211_1720c	COG1322	Protein conserved in bacteria
SanJ4211_1721c	COG1564	THIamine pyrophosphokinase
SanJ4211_1723c	COG1162	GTPase activity
SanJ4211_1724c	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SanJ4211_1728c	COG0084	hydrolase, TatD family'
SanJ4211_1729c	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SanJ4211_1733c	COG0594	ribonuclease P activity
SanJ4211_1735c	COG0166	Belongs to the GPI family
SanJ4211_1739c	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SanJ4211_1746	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SanJ4211_1747	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SanJ4211_1750c	COG4463	regulation of RNA biosynthetic process
SanJ4211_1753c	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SanJ4211_1754c	COG0052	Belongs to the universal ribosomal protein uS2 family
SanJ4211_1756c	COG0203	ribosomal protein L17
SanJ4211_1757c	COG0202	RNA polymerase activity
SanJ4211_1758c	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SanJ4211_1759c	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SanJ4211_1760c	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SanJ4211_1761c	COG0563	adenylate kinase activity
SanJ4211_1762c	COG0201	protein transport
SanJ4211_1763c	COG0200	Binds to the 23S rRNA
SanJ4211_1764c	COG1841	ribosomal large subunit assembly
SanJ4211_1765c	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SanJ4211_1767c	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SanJ4211_1769c	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SanJ4211_1770c	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SanJ4211_1771c	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SanJ4211_1772c	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SanJ4211_1773c	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SanJ4211_1775c	COG0255	Belongs to the universal ribosomal protein uL29 family
SanJ4211_1776c	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SanJ4211_1777c	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SanJ4211_1778c	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SanJ4211_1780c	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SanJ4211_1781c	COG0089	rRNA binding
SanJ4211_1782c	COG0088	Forms part of the polypeptide exit tunnel
SanJ4211_1783c	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SanJ4211_1784c	COG0051	transcription antitermination factor activity, RNA binding
SanJ4211_1787c	COG0572	uridine kinase
SanJ4211_1788c	COG0343	queuine tRNA-ribosyltransferase activity
SanJ4211_1791c	COG1832	CoA-binding protein
SanJ4211_1792c	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SanJ4211_1792c	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SanJ4211_1793c	COG5002	protein histidine kinase activity
SanJ4211_1800c	COG0438	transferase activity, transferring glycosyl groups
SanJ4211_1802c	COG0562	UDP-galactopyranose mutase
SanJ4211_1803c	COG3274	enterobacterial common antigen metabolic process
SanJ4211_1806c	COG1216	Glycosyl transferase, family 2
SanJ4211_1807c	COG1442	glycosyl transferase family 8
SanJ4211_1807c	COG1216	Glycosyl transferase, family 2
SanJ4211_1814c	COG3944	biosynthesis protein
SanJ4211_1815c	COG4464	protein tyrosine phosphatase activity
SanJ4211_1817c	COG0602	queuosine metabolic process
SanJ4211_1824c	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SanJ4211_1826c	COG0285	dihydrofolate synthase activity
SanJ4211_1827c	COG3906	Belongs to the UPF0473 family
SanJ4211_1828c	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SanJ4211_1829c	COG4472	Bacterial protein of unknown function (DUF965)
SanJ4211_1832c	COG1393	Belongs to the ArsC family
SanJ4211_1833c	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SanJ4211_1834c	COG1058	Belongs to the CinA family
SanJ4211_1834c	COG1546	Belongs to the CinA family
SanJ4211_1836c	COG0519	Catalyzes the synthesis of GMP from XMP
SanJ4211_1837c	COG0632	four-way junction helicase activity
SanJ4211_1838	COG3620	sequence-specific DNA binding
SanJ4211_1839c	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SanJ4211_1842c	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SanJ4211_1843c	COG1438	arginine binding
SanJ4211_1845c	COG1780	Probably involved in ribonucleotide reductase function
SanJ4211_1847c	COG0058	SHG alpha-glucan phosphorylase activity
SanJ4211_1848c	COG1640	4-alpha-glucanotransferase
SanJ4211_1849	COG2182	Extracellular solute-binding protein
SanJ4211_1850	COG1175	transmembrane transport
SanJ4211_1851	COG3833	ABC-type maltose transport systems, permease component
SanJ4211_1852	COG5521	maltodextrose utilization protein MalA
SanJ4211_1853	COG1609	Transcriptional regulator
SanJ4211_1854	COG1523	belongs to the glycosyl hydrolase 13 family
SanJ4211_1855c	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SanJ4211_1858c	COG0124	histidyl-tRNA synthetase
SanJ4211_1859	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SanJ4211_1869	COG2801	Transposase and inactivated derivatives
SanJ4211_1873	COG2807	transmembrane transport
SanJ4211_1874c	COG2094	Belongs to the DNA glycosylase MPG family
SanJ4211_1875	COG0561	phosphatase activity
SanJ4211_1876c	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SanJ4211_1877c	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SanJ4211_1878c	COG1696	Membrane protein involved in D-alanine export
SanJ4211_1889	COG0561	phosphatase activity
SanJ4211_1892c	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SanJ4211_1893c	COG1011	Hydrolase
SanJ4211_1895c	COG0305	Participates in initiation and elongation during chromosome replication
SanJ4211_1896c	COG0359	binds to the 23S rRNA
SanJ4211_1898c	COG0445	tRNA wobble uridine modification
SanJ4211_1899c	COG0482	sulfurtransferase activity
SanJ4211_1900c	COG1388	LysM domain
SanJ4211_1901	COG1760	l-serine dehydratase
SanJ4211_1902	COG1760	l-serine dehydratase
SanJ4211_1905c	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SanJ4211_1906c	COG1122	ATPase activity
SanJ4211_1907c	COG1122	ATPase activity
SanJ4211_1908c	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SanJ4211_1910c	COG0612	Peptidase, M16
SanJ4211_1911c	COG0612	Peptidase, M16
SanJ4211_1913	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SanJ4211_1915c	COG0180	Tryptophanyl-tRNA synthetase
SanJ4211_1916c	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SanJ4211_1917c	COG0149	triose-phosphate isomerase activity
SanJ4211_1919	COG0488	(ABC) transporter
SanJ4211_1924c	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SanJ4211_1925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SanJ4211_1926	COG1475	DNA binding