locus-tag	class	description
ASP0581_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ASP0581_00020	COG0592	DNA-directed DNA polymerase activity
ASP0581_00040	COG0012	GTP binding
ASP0581_00060	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ASP0581_00070	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ASP0581_00130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASP0581_00160	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ASP0581_00180	COG0756	dUTP diphosphatase activity
ASP0581_00200	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ASP0581_00240	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ASP0581_00280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASP0581_00280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASP0581_00290	COG1832	CoA-binding protein
ASP0581_00300	COG2855	membrane
ASP0581_00310	COG0436	Aminotransferase
ASP0581_00320	COG1381	Involved in DNA repair and RecF pathway recombination
ASP0581_00330	COG0416	fatty acid biosynthetic process
ASP0581_00340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASP0581_00370	COG2274	protein secretion by the type I secretion system
ASP0581_00380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASP0581_00400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ASP0581_00430	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ASP0581_00460	COG0151	Belongs to the GarS family
ASP0581_00470	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ASP0581_00500	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ASP0581_00510	COG3583	domain protein
ASP0581_00510	COG3064	Membrane
ASP0581_00510	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ASP0581_00540	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASP0581_00550	COG3715	PTS system
ASP0581_00560	COG3716	PTS system mannose fructose sorbose family IID component
ASP0581_00580	COG2222	sugar isomerase
ASP0581_00600	COG2514	catechol 2,3-dioxygenase activity
ASP0581_00650	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASP0581_00660	COG0569	domain protein
ASP0581_00680	COG1215	transferase activity, transferring glycosyl groups
ASP0581_00730	COG5002	protein histidine kinase activity
ASP0581_00740	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ASP0581_00750	COG0582	viral genome integration into host DNA
ASP0581_00870	COG4209	transmembrane transport
ASP0581_00880	COG0395	ABC-type sugar transport system, permease component
ASP0581_00950	COG1695	Transcriptional regulator
ASP0581_01000	COG0546	phosphoglycolate phosphatase activity
ASP0581_01010	COG1760	l-serine dehydratase
ASP0581_01020	COG1760	l-serine dehydratase
ASP0581_01050	COG2274	protein secretion by the type I secretion system
ASP0581_01260	COG0494	nUDIX hydrolase
ASP0581_01270	COG0445	tRNA wobble uridine modification
ASP0581_01320	COG1214	PFAM Peptidase M22, glycoprotease
ASP0581_01390	COG0438	transferase activity, transferring glycosyl groups
ASP0581_01460	COG1396	sequence-specific DNA binding
ASP0581_01540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASP0581_01550	COG1464	Belongs to the NlpA lipoprotein family
ASP0581_01560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASP0581_01570	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ASP0581_01610	COG2972	Histidine kinase
ASP0581_01620	COG2207	Transcriptional regulator
ASP0581_01620	COG4753	response regulator
ASP0581_01640	COG1780	Probably involved in ribonucleotide reductase function
ASP0581_01720	COG0019	diaminopimelate decarboxylase activity
ASP0581_01760	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ASP0581_01770	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ASP0581_01780	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASP0581_01780	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASP0581_01820	COG2818	Glycosylase
ASP0581_01870	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ASP0581_01880	COG0006	proline dipeptidase activity
ASP0581_01890	COG1393	Belongs to the ArsC family
ASP0581_01910	COG4472	Bacterial protein of unknown function (DUF965)
ASP0581_01920	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ASP0581_01930	COG3906	Belongs to the UPF0473 family
ASP0581_01940	COG0285	dihydrofolate synthase activity
ASP0581_01960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASP0581_02020	COG0602	queuosine metabolic process
ASP0581_02040	COG0051	transcription antitermination factor activity, RNA binding
ASP0581_02050	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ASP0581_02060	COG0088	Forms part of the polypeptide exit tunnel
ASP0581_02070	COG0089	rRNA binding
ASP0581_02080	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ASP0581_02090	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ASP0581_02100	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ASP0581_02110	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ASP0581_02120	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ASP0581_02130	COG0255	Belongs to the universal ribosomal protein uL29 family
ASP0581_02140	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ASP0581_02150	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ASP0581_02160	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ASP0581_02170	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ASP0581_02180	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ASP0581_02190	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ASP0581_02210	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ASP0581_02220	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ASP0581_02230	COG1841	ribosomal large subunit assembly
ASP0581_02240	COG0200	Binds to the 23S rRNA
ASP0581_02250	COG0201	protein transport
ASP0581_02270	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ASP0581_02280	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ASP0581_02290	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ASP0581_02300	COG0202	RNA polymerase activity
ASP0581_02310	COG0203	ribosomal protein L17
ASP0581_02320	COG3830	Belongs to the UPF0237 family
ASP0581_02370	COG3842	ATPase activity
ASP0581_02380	COG3842	ATPase activity
ASP0581_02390	COG3842	ATPase activity
ASP0581_02430	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ASP0581_02440	COG1349	DNA-binding transcription factor activity
ASP0581_02460	COG1447	Phosphotransferase system cellobiose-specific component IIA
ASP0581_02470	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASP0581_02480	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASP0581_02520	COG0495	leucyl-tRNA aminoacylation
ASP0581_02590	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ASP0581_02600	COG4589	Belongs to the CDS family
ASP0581_02610	COG0750	zinc metalloprotease
ASP0581_02630	COG2723	6-phospho-beta-galactosidase activity
ASP0581_02640	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ASP0581_02660	COG1523	belongs to the glycosyl hydrolase 13 family
ASP0581_02670	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ASP0581_02680	COG0049	tRNA binding
ASP0581_02700	COG2176	DNA-directed DNA polymerase activity
ASP0581_02740	COG2309	aminopeptidase activity
ASP0581_02750	COG2261	transglycosylase associated protein
ASP0581_02760	COG1187	pseudouridine synthase activity
ASP0581_02770	COG3579	cysteine-type endopeptidase activity
ASP0581_02780	COG3716	PTS system mannose fructose sorbose family IID component
ASP0581_02790	COG3715	PTS system
ASP0581_02810	COG1064	alcohol dehydrogenase
ASP0581_02820	COG0561	phosphatase activity
ASP0581_02830	COG2252	PERMEase
ASP0581_02850	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ASP0581_02860	COG0285	dihydrofolate synthase activity
ASP0581_02880	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ASP0581_02880	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ASP0581_02900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ASP0581_02910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ASP0581_03020	COG1373	ATPase (AAA superfamily
ASP0581_03060	COG2723	6-phospho-beta-galactosidase activity
ASP0581_03090	COG3711	transcriptional antiterminator
ASP0581_03090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASP0581_03150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASP0581_03180	COG0386	Belongs to the glutathione peroxidase family
ASP0581_03190	COG5492	domain, Protein
ASP0581_03200	COG1943	Transposase
ASP0581_03240	COG1028	Short-chain dehydrogenase reductase Sdr
ASP0581_03260	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ASP0581_03270	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASP0581_03280	COG3715	PTS system
ASP0581_03290	COG3716	PTS system mannose fructose sorbose family IID component
ASP0581_03320	COG1609	Transcriptional regulator
ASP0581_03380	COG4839	cell division protein FtsL
ASP0581_03390	COG0768	penicillin binding
ASP0581_03420	COG1854	S-ribosylhomocysteine lyase activity
ASP0581_03430	COG4868	Belongs to the UPF0371 family
ASP0581_03440	COG0366	Alpha amylase catalytic
ASP0581_03470	COG4464	protein tyrosine phosphatase activity
ASP0581_03480	COG3944	biosynthesis protein
ASP0581_03490	COG0489	protein tyrosine kinase activity
ASP0581_03580	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ASP0581_03590	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ASP0581_03620	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ASP0581_03640	COG4372	Transposase
ASP0581_03650	COG3335	DDE superfamily endonuclease
ASP0581_03700	COG4166	transmembrane transport
ASP0581_03710	COG0366	Alpha amylase catalytic
ASP0581_03720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ASP0581_03730	COG3331	DNA recombination
ASP0581_03740	COG4474	Belongs to the UPF0398 family
ASP0581_03750	COG3599	regulation of cell shape
ASP0581_03760	COG0116	Belongs to the methyltransferase superfamily
ASP0581_03780	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ASP0581_03790	COG0745	RESPONSE REGULATOR receiver
ASP0581_03860	COG4585	Histidine kinase
ASP0581_03870	COG2197	response regulator
ASP0581_03930	COG2801	Transposase and inactivated derivatives
ASP0581_03940	COG2801	Transposase and inactivated derivatives
ASP0581_03970	COG2213	PTS system mannitol-specific
ASP0581_03980	COG3711	transcriptional antiterminator
ASP0581_03990	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASP0581_04010	COG0544	peptidyl-prolyl cis-trans isomerase activity
ASP0581_04020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ASP0581_04030	COG0681	Belongs to the peptidase S26 family
ASP0581_04040	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ASP0581_04070	COG1193	negative regulation of DNA recombination
ASP0581_04080	COG1115	amino acid carrier protein
ASP0581_04130	COG0527	aspartate kinase activity
ASP0581_04140	COG1024	Enoyl-CoA hydratase
ASP0581_04150	COG1846	Transcriptional regulator
ASP0581_04160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASP0581_04170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASP0581_04190	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ASP0581_04200	COG1028	Short-chain dehydrogenase reductase Sdr
ASP0581_04210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASP0581_04230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASP0581_04240	COG0439	Biotin carboxylase
ASP0581_04250	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ASP0581_04260	COG0825	malonyl-CoA metabolic process
ASP0581_04300	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASP0581_04320	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASP0581_04330	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASP0581_04360	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ASP0581_04380	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ASP0581_04400	COG1461	Dihydroxyacetone kinase
ASP0581_04420	COG0028	Belongs to the TPP enzyme family
ASP0581_04430	COG0440	acetolactate synthase activity
ASP0581_04440	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ASP0581_04470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ASP0581_04500	COG0765	amino acid transport
ASP0581_04530	COG1968	undecaprenyl-diphosphatase activity
ASP0581_04540	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ASP0581_04550	COG1882	Formate acetyltransferase
ASP0581_04590	COG1846	Transcriptional regulator
ASP0581_04590	COG1940	carbohydrate kinase activity
ASP0581_04600	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASP0581_04620	COG1447	Phosphotransferase system cellobiose-specific component IIA
ASP0581_04630	COG2723	6-phospho-beta-galactosidase activity
ASP0581_04640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASP0581_04640	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASP0581_04650	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASP0581_04660	COG0569	domain protein
ASP0581_04700	COG1122	ATPase activity
ASP0581_04730	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ASP0581_04740	COG0671	phosphoesterase, PA-phosphatase related
ASP0581_04760	COG3343	RNA polymerase activity
ASP0581_04770	COG0504	CTP synthase activity
ASP0581_04780	COG1283	sodium-dependent phosphate transmembrane transporter activity
ASP0581_04820	COG0789	Transcriptional regulator
ASP0581_04830	COG0174	glutamine synthetase
ASP0581_04850	COG0732	type I restriction modification DNA specificity domain
ASP0581_04870	COG4974	Belongs to the 'phage' integrase family
ASP0581_04890	COG0732	type I restriction modification DNA specificity domain
ASP0581_04950	COG0443	Heat shock 70 kDa protein
ASP0581_04970	COG0484	heat shock protein binding
ASP0581_04990	COG0537	adenosine 5'-monophosphoramidase activity
ASP0581_05000	COG1131	(ABC) transporter
ASP0581_05050	COG3290	protein histidine kinase activity
ASP0581_05070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASP0581_05080	COG2274	protein secretion by the type I secretion system
ASP0581_05090	COG2274	protein secretion by the type I secretion system
ASP0581_05230	COG0195	Participates in both transcription termination and antitermination
ASP0581_05240	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ASP0581_05270	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ASP0581_05350	COG0519	Catalyzes the synthesis of GMP from XMP
ASP0581_05370	COG0525	valine-tRNA ligase activity
ASP0581_05440	COG3711	transcriptional antiterminator
ASP0581_05450	COG2190	(PTS) system
ASP0581_05450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASP0581_05450	COG1263	PTS System
ASP0581_05480	COG0456	acetyltransferase
ASP0581_05490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASP0581_05490	COG0072	phenylalanine-tRNA ligase activity
ASP0581_05530	COG3620	sequence-specific DNA binding
ASP0581_05570	COG1045	serine acetyltransferase
ASP0581_05590	COG0215	cysteine-tRNA ligase activity
ASP0581_05600	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ASP0581_05630	COG0577	efflux transmembrane transporter activity
ASP0581_05640	COG1136	(ABC) transporter
ASP0581_05650	COG0577	efflux transmembrane transporter activity
ASP0581_05660	COG0745	RESPONSE REGULATOR receiver
ASP0581_05670	COG5002	protein histidine kinase activity
ASP0581_05680	COG0191	fructose-bisphosphate aldolase activity
ASP0581_05690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASP0581_05700	COG0765	amino acid transport
ASP0581_05710	COG0765	amino acid transport
ASP0581_05720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASP0581_05740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ASP0581_05740	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ASP0581_05820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASP0581_05850	COG1573	uracil-dna glycosylase
ASP0581_05870	COG1114	Component of the transport system for branched-chain amino acids
ASP0581_05880	COG1363	Peptidase, m42
ASP0581_05910	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ASP0581_05920	COG0081	regulation of translation
ASP0581_05970	COG4555	ABC transporter
ASP0581_06030	COG1404	Belongs to the peptidase S8 family
ASP0581_06060	COG3775	system Galactitol-specific IIC component
ASP0581_06070	COG3250	beta-galactosidase activity
ASP0581_06110	COG1242	4 iron, 4 sulfur cluster binding
ASP0581_06120	COG1242	4 iron, 4 sulfur cluster binding
ASP0581_06130	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ASP0581_06170	COG0785	Cytochrome C biogenesis protein
ASP0581_06180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASP0581_06190	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASP0581_06190	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASP0581_06200	COG4753	response regulator
ASP0581_06200	COG2207	Transcriptional regulator
ASP0581_06210	COG2972	Histidine kinase
ASP0581_06220	COG4475	Protein of unknown function (DUF436)
ASP0581_06230	COG3064	Membrane
ASP0581_06240	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASP0581_06270	COG1940	carbohydrate kinase activity
ASP0581_06280	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ASP0581_06300	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ASP0581_06310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ASP0581_06320	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ASP0581_06340	COG0300	oxidoreductase activity
ASP0581_06370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASP0581_06390	COG1187	pseudouridine synthase activity
ASP0581_06440	COG1136	(ABC) transporter
ASP0581_06470	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ASP0581_06480	COG0284	orotidine-5'-phosphate decarboxylase activity
ASP0581_06490	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ASP0581_06530	COG1131	(ABC) transporter
ASP0581_06540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASP0581_06550	COG1126	abc transporter atp-binding protein
ASP0581_06570	COG0765	amino acid transport
ASP0581_06590	COG1304	FMN binding
ASP0581_06600	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ASP0581_06610	COG1304	FMN binding
ASP0581_06630	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ASP0581_06640	COG0352	thiamine-phosphate diphosphorylase activity
ASP0581_06660	COG4172	Belongs to the ABC transporter superfamily
ASP0581_06680	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ASP0581_06710	COG0352	thiamine-phosphate diphosphorylase activity
ASP0581_06750	COG2217	Heavy metal translocating P-type atpase
ASP0581_06760	COG0028	Belongs to the TPP enzyme family
ASP0581_06790	COG3335	DDE superfamily endonuclease
ASP0581_06810	COG2723	6-phospho-beta-galactosidase activity
ASP0581_06820	COG1482	cell wall glycoprotein biosynthetic process
ASP0581_06830	COG0733	neurotransmitter:sodium symporter activity
ASP0581_06840	COG0789	Transcriptional regulator
ASP0581_06860	COG2081	HI0933 family
ASP0581_06870	COG1307	EDD domain protein, DegV family
ASP0581_06890	COG2131	deaminase
ASP0581_06900	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ASP0581_06910	COG0740	serine-type endopeptidase activity
ASP0581_06920	COG4471	UPF0298 protein
ASP0581_06940	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASP0581_06960	COG0411	ABC transporter
ASP0581_06970	COG0410	ABC transporter
ASP0581_06980	COG0517	IMP dehydrogenase activity
ASP0581_06990	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ASP0581_07000	COG2884	Cell division ATP-binding protein ftsE
ASP0581_07010	COG2177	Part of the ABC transporter FtsEX involved in
ASP0581_07020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASP0581_07020	COG2190	(PTS) system
ASP0581_07020	COG1263	PTS System
ASP0581_07040	COG0513	Belongs to the DEAD box helicase family
ASP0581_07050	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ASP0581_07060	COG0167	dihydroorotate dehydrogenase activity
ASP0581_07080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ASP0581_07090	COG4470	Protein conserved in bacteria
ASP0581_07110	COG0488	(ABC) transporter
ASP0581_07140	COG0228	four-way junction DNA binding
ASP0581_07150	COG1837	Belongs to the UPF0109 family
ASP0581_07170	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ASP0581_07190	COG1328	CTP reductase activity
ASP0581_07190	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ASP0581_07210	COG4443	Transcriptional Coactivator p15 (PC4)
ASP0581_07220	COG1268	BioY protein
ASP0581_07230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASP0581_07240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASP0581_07250	COG1136	(ABC) transporter
ASP0581_07260	COG0577	efflux transmembrane transporter activity
ASP0581_07270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASP0581_07270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASP0581_07300	COG4989	oxidoreductase activity
ASP0581_07320	COG1028	Short-chain dehydrogenase reductase Sdr
ASP0581_07380	COG0745	RESPONSE REGULATOR receiver
ASP0581_07390	COG5002	protein histidine kinase activity
ASP0581_07430	COG0772	Belongs to the SEDS family
ASP0581_07440	COG0693	protein deglycase activity
ASP0581_07460	COG0187	DNA topoisomerase II activity
ASP0581_07470	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ASP0581_07490	COG3335	DDE superfamily endonuclease
ASP0581_07540	COG2801	Transposase and inactivated derivatives
ASP0581_07590	COG0542	response to heat
ASP0581_07600	COG4703	Protein of unknown function (DUF1797)
ASP0581_07610	COG0765	amino acid transport
ASP0581_07620	COG1126	abc transporter atp-binding protein
ASP0581_07630	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ASP0581_07640	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ASP0581_07650	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ASP0581_07680	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ASP0581_07720	COG0813	purine-nucleoside phosphorylase activity
ASP0581_07770	COG2813	Specifically methylates the guanine in position
ASP0581_07780	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ASP0581_07790	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ASP0581_07800	COG0295	cytidine deaminase activity
ASP0581_07810	COG1744	ABC transporter substrate-binding protein PnrA-like
ASP0581_07880	COG2801	Transposase and inactivated derivatives
ASP0581_07890	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ASP0581_07900	COG0187	DNA topoisomerase II activity
ASP0581_07920	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ASP0581_07930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASP0581_07940	COG4166	transmembrane transport
ASP0581_07970	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ASP0581_07990	COG0539	negative regulation of cytoplasmic translation
ASP0581_08030	COG1956	GAF domain-containing protein
ASP0581_08040	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ASP0581_08070	COG0719	Fe-S assembly protein
ASP0581_08080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ASP0581_08100	COG0719	Fe-S assembly protein
ASP0581_08110	COG1686	Belongs to the peptidase S11 family
ASP0581_08120	COG0628	permease
ASP0581_08130	COG1349	DNA-binding transcription factor activity
ASP0581_08140	COG1105	Belongs to the carbohydrate kinase PfkB family
ASP0581_08150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASP0581_08150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASP0581_08150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASP0581_08160	COG1674	ftsk spoiiie
ASP0581_08160	COG0697	spore germination
ASP0581_08190	COG1104	cysteine desulfurase activity
ASP0581_08340	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ASP0581_08370	COG1438	arginine binding
ASP0581_08410	COG0469	pyruvate kinase activity
ASP0581_08470	COG3689	TIGRFAM TIGR03943 family protein
ASP0581_08480	COG0701	Predicted permease
ASP0581_08510	COG3955	Domain of unknown function (DUF1919)
ASP0581_08520	COG2183	response to ionizing radiation
ASP0581_08560	COG1136	(ABC) transporter
ASP0581_08570	COG0577	efflux transmembrane transporter activity
ASP0581_08600	COG1982	Orn Lys Arg decarboxylase major
ASP0581_08620	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ASP0581_08660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASP0581_08670	COG0561	phosphatase activity
ASP0581_08700	COG0583	DNA-binding transcription factor activity
ASP0581_08710	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ASP0581_08720	COG0564	pseudouridine synthase activity
ASP0581_08730	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ASP0581_08760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ASP0581_08780	COG0470	DNA polymerase III
ASP0581_08790	COG4467	Involved in initiation control of chromosome replication
ASP0581_08870	COG0528	UMP kinase activity
ASP0581_08890	COG2996	Protein conserved in bacteria
ASP0581_08900	COG4479	Belongs to the UPF0346 family
ASP0581_08910	COG1702	phosphate starvation-inducible protein PhoH
ASP0581_08940	COG0686	Belongs to the AlaDH PNT family
ASP0581_08950	COG0686	Belongs to the AlaDH PNT family
ASP0581_08960	COG0686	Belongs to the AlaDH PNT family
ASP0581_08970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASP0581_08980	COG1596	polysaccharide export
ASP0581_08980	COG1555	photosystem II stabilization
ASP0581_08990	COG2333	competence protein COMEC
ASP0581_08990	COG0658	competence protein
ASP0581_09030	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ASP0581_09040	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ASP0581_09050	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ASP0581_09070	COG0543	2 iron, 2 sulfur cluster binding
ASP0581_09080	COG0167	dihydroorotate dehydrogenase activity
ASP0581_09090	COG4193	domain, Protein
ASP0581_09090	COG5263	repeat protein
ASP0581_09110	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ASP0581_09120	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ASP0581_09130	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ASP0581_09140	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ASP0581_09150	COG0237	dephospho-CoA kinase activity
ASP0581_09160	COG2814	Major facilitator Superfamily
ASP0581_09180	COG0557	exoribonuclease II activity
ASP0581_09190	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ASP0581_09200	COG0500	methyltransferase
ASP0581_09200	COG3615	Tellurite resistance protein tehB
ASP0581_09240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASP0581_09250	COG2801	Transposase and inactivated derivatives
ASP0581_09280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ASP0581_09310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASP0581_09320	COG0494	nUDIX hydrolase
ASP0581_09340	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ASP0581_09360	COG2176	DNA-directed DNA polymerase activity
ASP0581_09370	COG0584	glycerophosphoryl diester phosphodiesterase
ASP0581_09410	COG0785	Cytochrome C biogenesis protein
ASP0581_09420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASP0581_09430	COG0531	amino acid
ASP0581_09440	COG3443	Belongs to the bacterial solute-binding protein 9 family
ASP0581_09440	COG0803	Belongs to the bacterial solute-binding protein 9 family
ASP0581_09520	COG1970	mechanosensitive ion channel activity
ASP0581_09540	COG4708	membrane
ASP0581_09550	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASP0581_09570	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ASP0581_09580	COG1942	4-Oxalocrotonate Tautomerase
ASP0581_09590	COG1435	thymidine kinase activity
ASP0581_09610	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ASP0581_09620	COG2890	protein-(glutamine-N5) methyltransferase activity
ASP0581_09670	COG0741	lytic transglycosylase activity
ASP0581_09690	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASP0581_09730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASP0581_09740	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASP0581_09840	COG1597	lipid kinase activity
ASP0581_09850	COG0366	Alpha amylase catalytic
ASP0581_09860	COG0366	Alpha amylase catalytic
ASP0581_09920	COG0772	Belongs to the SEDS family
ASP0581_09930	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ASP0581_09960	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ASP0581_09970	COG0358	DNA primase activity
ASP0581_09980	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASP0581_09990	COG2151	metal-sulfur cluster biosynthetic enzyme
ASP0581_10000	COG0438	transferase activity, transferring glycosyl groups
ASP0581_10010	COG0438	transferase activity, transferring glycosyl groups
ASP0581_10060	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ASP0581_10080	COG4109	DRTGG domain
ASP0581_10090	COG0024	Methionine aminopeptidase
ASP0581_10120	COG0210	DNA helicase
ASP0581_10140	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ASP0581_10180	COG1104	cysteine desulfurase activity
ASP0581_10190	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ASP0581_10210	COG2357	RelA SpoT domain protein
ASP0581_10220	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ASP0581_10230	COG0564	pseudouridine synthase activity
ASP0581_10240	COG0280	phosphate acetyltransferase
ASP0581_10270	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ASP0581_10290	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ASP0581_10310	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ASP0581_10320	COG0196	riboflavin kinase activity
ASP0581_10330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ASP0581_10340	COG1307	EDD domain protein, DegV family
ASP0581_10360	COG0488	(ABC) transporter
ASP0581_10400	COG1523	belongs to the glycosyl hydrolase 13 family
ASP0581_10410	COG1012	belongs to the aldehyde dehydrogenase family
ASP0581_10420	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ASP0581_10480	COG0560	Phosphoserine phosphatase
ASP0581_10490	COG0560	Phosphoserine phosphatase
ASP0581_10540	COG1074	ATP-dependent DNA helicase activity
ASP0581_10560	COG3583	domain protein
ASP0581_10560	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ASP0581_10590	COG0270	DNA (cytosine-5-)-methyltransferase activity
ASP0581_10760	COG1674	ftsk spoiiie
ASP0581_10770	COG2946	Replication initiation factor
ASP0581_10850	COG0791	NLP P60 protein
ASP0581_10850	COG0741	lytic transglycosylase activity
ASP0581_10930	COG1136	(ABC) transporter
ASP0581_11040	COG1396	sequence-specific DNA binding
ASP0581_11050	COG0542	response to heat
ASP0581_11110	COG0366	Alpha amylase catalytic
ASP0581_11130	COG1396	sequence-specific DNA binding
ASP0581_11140	COG0542	response to heat
ASP0581_11160	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ASP0581_11220	COG1396	sequence-specific DNA binding
ASP0581_11250	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ASP0581_11290	COG0095	Lipoate-protein ligase
ASP0581_11300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASP0581_11310	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASP0581_11320	COG0022	dehydrogenase e1 component
ASP0581_11330	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ASP0581_11340	COG0534	Mate efflux family protein
ASP0581_11360	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ASP0581_11370	COG1051	belongs to the nudix hydrolase family
ASP0581_11380	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ASP0581_11400	COG1011	Hydrolase
ASP0581_11410	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ASP0581_11450	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ASP0581_11460	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASP0581_11470	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASP0581_11520	COG2723	6-phospho-beta-galactosidase activity
ASP0581_11550	COG3711	transcriptional antiterminator
ASP0581_11560	COG3684	Belongs to the aldolase LacD family
ASP0581_11580	COG0698	ribose 5-phosphate isomerase
ASP0581_11590	COG0698	ribose 5-phosphate isomerase
ASP0581_11660	COG0481	GTPase activity
ASP0581_11670	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ASP0581_11680	COG0497	DNA recombination
ASP0581_11690	COG1438	arginine binding
ASP0581_11700	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ASP0581_11720	COG1722	exodeoxyribonuclease VII activity
ASP0581_11730	COG1570	exodeoxyribonuclease VII activity
ASP0581_11740	COG0572	uridine kinase
ASP0581_11770	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ASP0581_11790	COG2873	o-acetylhomoserine
ASP0581_11830	COG3764	Sortase (surface protein transpeptidase)
ASP0581_11840	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ASP0581_11850	COG0039	L-malate dehydrogenase activity
ASP0581_11900	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ASP0581_11910	COG5002	protein histidine kinase activity
ASP0581_11920	COG0745	RESPONSE REGULATOR receiver
ASP0581_11930	COG1194	a g-specific adenine glycosylase
ASP0581_11960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ASP0581_11970	COG4684	Psort location CytoplasmicMembrane, score
ASP0581_11990	COG1827	regulation of RNA biosynthetic process
ASP0581_12000	COG2816	NAD+ diphosphatase activity
ASP0581_12050	COG0765	amino acid transport
ASP0581_12060	COG1126	abc transporter atp-binding protein
ASP0581_12070	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ASP0581_12080	COG0552	protein localization to endoplasmic reticulum
ASP0581_12090	COG0561	phosphatase activity
ASP0581_12100	COG0561	phosphatase activity
ASP0581_12110	COG1196	nuclear chromosome segregation
ASP0581_12150	COG1401	restriction endodeoxyribonuclease activity
ASP0581_12180	COG0066	3-isopropylmalate dehydratase activity
ASP0581_12190	COG0473	3-isopropylmalate dehydrogenase activity
ASP0581_12200	COG0473	3-isopropylmalate dehydrogenase activity
ASP0581_12230	COG3142	Participates in the control of copper homeostasis
ASP0581_12240	COG2832	Protein of unknown function (DUF454)
ASP0581_12250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ASP0581_12270	COG0758	DNA mediated transformation
ASP0581_12280	COG4750	Nucleotidyl transferase
ASP0581_12310	COG1063	alcohol dehydrogenase
ASP0581_12340	COG3475	LICD family
ASP0581_12350	COG3475	LICD family
ASP0581_12360	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ASP0581_12370	COG0505	Belongs to the CarA family
ASP0581_12390	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ASP0581_12400	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ASP0581_12420	COG0488	(ABC) transporter
ASP0581_12440	COG1704	LemA family
ASP0581_12470	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ASP0581_12480	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ASP0581_12500	COG1078	dGTPase activity
ASP0581_12530	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ASP0581_12540	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ASP0581_12550	COG0077	Prephenate dehydratase
ASP0581_12550	COG1605	Chorismate mutase
ASP0581_12560	COG0716	FMN binding
ASP0581_12570	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ASP0581_12580	COG0254	rRNA binding
ASP0581_12610	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ASP0581_12700	COG2801	Transposase and inactivated derivatives
ASP0581_12780	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASP0581_12790	COG1269	ATP hydrolysis coupled proton transport
ASP0581_12820	COG0673	inositol 2-dehydrogenase activity
ASP0581_12830	COG4409	exo-alpha-(2->6)-sialidase activity
ASP0581_12850	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASP0581_12860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASP0581_12870	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ASP0581_12880	COG1737	Transcriptional regulator
ASP0581_12930	COG0577	efflux transmembrane transporter activity
ASP0581_12930	COG1136	(ABC) transporter
ASP0581_12950	COG0515	serine threonine protein kinase
ASP0581_13020	COG0222	ribosome binding
ASP0581_13030	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ASP0581_13040	COG0402	S-adenosylhomocysteine deaminase activity
ASP0581_13060	COG1132	(ABC) transporter
ASP0581_13070	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASP0581_13070	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASP0581_13090	COG0083	homoserine kinase activity
ASP0581_13140	COG1215	transferase activity, transferring glycosyl groups
ASP0581_13160	COG3475	LICD family
ASP0581_13170	COG1316	TRANSCRIPTIONal
ASP0581_13180	COG0077	Prephenate dehydratase
ASP0581_13190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ASP0581_13210	COG3679	Belongs to the UPF0342 family
ASP0581_13220	COG0287	Prephenate dehydrogenase
ASP0581_13230	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ASP0581_13250	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ASP0581_13260	COG0710	3-dehydroquinate dehydratase activity
ASP0581_13270	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ASP0581_13300	COG1131	(ABC) transporter
ASP0581_13350	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ASP0581_13380	COG3842	ATPase activity
ASP0581_13420	COG3527	Alpha-acetolactate decarboxylase
ASP0581_13430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASP0581_13440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASP0581_13450	COG0704	Plays a role in the regulation of phosphate uptake
ASP0581_13460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASP0581_13470	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASP0581_13480	COG0581	inorganic phosphate transmembrane transporter activity
ASP0581_13490	COG0573	inorganic phosphate transmembrane transporter activity
ASP0581_13500	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ASP0581_13510	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ASP0581_13510	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ASP0581_13520	COG0483	inositol monophosphate 1-phosphatase activity
ASP0581_13530	COG4476	Belongs to the UPF0223 family
ASP0581_13540	COG1393	Belongs to the ArsC family
ASP0581_13560	COG0647	UMP catabolic process
ASP0581_13580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASP0581_13610	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ASP0581_13630	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ASP0581_13650	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ASP0581_13670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASP0581_13690	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ASP0581_13730	COG1131	(ABC) transporter
ASP0581_13820	COG1132	(ABC) transporter
ASP0581_13830	COG1132	(ABC) transporter
ASP0581_13890	COG1129	ABC transporter
ASP0581_13900	COG4372	Transposase
ASP0581_13930	COG0519	Catalyzes the synthesis of GMP from XMP
ASP0581_13930	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ASP0581_13950	COG0697	spore germination
ASP0581_13960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ASP0581_13990	COG0561	phosphatase activity
ASP0581_14030	COG0242	peptide deformylase activity
ASP0581_14050	COG0492	ferredoxin-NADP+ reductase activity
ASP0581_14070	COG1126	abc transporter atp-binding protein
ASP0581_14090	COG1393	Belongs to the ArsC family
ASP0581_14100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ASP0581_14130	COG1272	protein, Hemolysin III
ASP0581_14150	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ASP0581_14190	COG0431	NADPH-dependent FMN reductase
ASP0581_14190	COG1053	succinate dehydrogenase
ASP0581_14190	COG3976	FMN-binding domain protein
ASP0581_14250	COG0656	L-ascorbic acid biosynthetic process
ASP0581_14260	COG0726	polysaccharide deacetylase
ASP0581_14340	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASP0581_14350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ASP0581_14430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASP0581_14450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASP0581_14460	COG1126	abc transporter atp-binding protein
ASP0581_14490	COG0628	permease
ASP0581_14500	COG2706	6-phosphogluconolactonase activity
ASP0581_14510	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ASP0581_14520	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ASP0581_14550	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASP0581_14560	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ASP0581_14610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASP0581_14620	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ASP0581_14670	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ASP0581_14680	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ASP0581_14690	COG0626	cystathionine gamma-synthase activity
ASP0581_14700	COG1132	(ABC) transporter
ASP0581_14720	COG4166	transmembrane transport
ASP0581_14730	COG2244	polysaccharide biosynthetic process
ASP0581_14740	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ASP0581_14780	COG1227	inorganic diphosphatase activity
ASP0581_14790	COG2827	Endonuclease containing a URI domain
ASP0581_14800	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ASP0581_14810	COG1098	S1 RNA binding domain
ASP0581_14830	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ASP0581_14840	COG0629	single-stranded DNA binding
ASP0581_14850	COG0360	Binds together with S18 to 16S ribosomal RNA
ASP0581_14860	COG0017	Asparaginyl-tRNA synthetase
ASP0581_14880	COG0436	Aminotransferase
ASP0581_14920	COG3711	transcriptional antiterminator
ASP0581_14930	COG3022	response to hydroperoxide
ASP0581_14960	COG0242	peptide deformylase activity
ASP0581_14970	COG0625	glutathione transferase activity
ASP0581_14990	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ASP0581_15000	COG0488	(ABC) transporter
ASP0581_15010	COG0617	tRNA 3'-terminal CCA addition
ASP0581_15030	COG1307	EDD domain protein, DegV family
ASP0581_15070	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ASP0581_15100	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ASP0581_15120	COG0251	oxidation-reduction process
ASP0581_15130	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ASP0581_15140	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ASP0581_15150	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ASP0581_15180	COG4193	domain, Protein
ASP0581_15180	COG5263	repeat protein
ASP0581_15190	COG0149	triose-phosphate isomerase activity
ASP0581_15200	COG3935	DnaD domain protein
ASP0581_15210	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ASP0581_15230	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ASP0581_15240	COG2226	methyltransferase
ASP0581_15250	COG3842	ATPase activity
ASP0581_15260	COG1335	isochorismatase
ASP0581_15270	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ASP0581_15280	COG0513	Belongs to the DEAD box helicase family
ASP0581_15300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASP0581_15310	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ASP0581_15320	COG3442	glutamine amidotransferase
ASP0581_15330	COG0006	proline dipeptidase activity
ASP0581_15340	COG2801	Transposase and inactivated derivatives
ASP0581_15370	COG4720	Psort location CytoplasmicMembrane, score
ASP0581_15380	COG0351	phosphomethylpyrimidine kinase
ASP0581_15390	COG0101	tRNA pseudouridine synthase activity
ASP0581_15420	COG2824	Alkylphosphonate utilization operon protein PhnA
ASP0581_15430	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ASP0581_15460	COG0463	Glycosyl transferase, family 2
ASP0581_15470	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ASP0581_15490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASP0581_15500	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ASP0581_15510	COG2384	SAM-dependent methyltransferase
ASP0581_15570	COG2801	Transposase and inactivated derivatives
ASP0581_15590	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ASP0581_15600	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ASP0581_15610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASP0581_15610	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ASP0581_15610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASP0581_15620	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASP0581_15660	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ASP0581_15670	COG0204	Acyl-transferase
ASP0581_15690	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ASP0581_15700	COG2910	NAD(P)H-binding
ASP0581_15730	COG5002	protein histidine kinase activity
ASP0581_15740	COG0745	RESPONSE REGULATOR receiver
ASP0581_15770	COG1959	2 iron, 2 sulfur cluster binding
ASP0581_15840	COG1490	D-aminoacyl-tRNA deacylase activity
ASP0581_15880	COG3590	peptidase
ASP0581_15910	COG0803	Belongs to the bacterial solute-binding protein 9 family
ASP0581_15920	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ASP0581_15940	COG1136	(ABC) transporter
ASP0581_15940	COG0577	efflux transmembrane transporter activity
ASP0581_15970	COG0588	phosphoglycerate mutase activity
ASP0581_16000	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ASP0581_16010	COG3599	regulation of cell shape
ASP0581_16040	COG1799	cell septum assembly
ASP0581_16050	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ASP0581_16090	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ASP0581_16110	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ASP0581_16120	COG0768	penicillin binding
ASP0581_16150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASP0581_16190	COG2731	YhcH YjgK YiaL family protein
ASP0581_16210	COG0395	ABC-type sugar transport system, permease component
ASP0581_16220	COG1175	transmembrane transport
ASP0581_16240	COG1263	PTS System
ASP0581_16240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASP0581_16240	COG2190	(PTS) system
ASP0581_16250	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ASP0581_16260	COG0673	inositol 2-dehydrogenase activity
ASP0581_16270	COG0673	inositol 2-dehydrogenase activity
ASP0581_16300	COG1175	transmembrane transport
ASP0581_16310	COG1653	transport
ASP0581_16370	COG3458	cephalosporin-C deacetylase activity
ASP0581_16380	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ASP0581_16390	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASP0581_16400	COG0736	holo-[acyl-carrier-protein] synthase activity
ASP0581_16410	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASP0581_16420	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASP0581_16490	COG1160	GTP binding
ASP0581_16500	COG0778	Nitroreductase
ASP0581_16510	COG1484	DNA-dependent DNA replication
ASP0581_16530	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ASP0581_16540	COG1725	Transcriptional regulator
ASP0581_16550	COG1131	(ABC) transporter
ASP0581_16570	COG1668	transmembrane transport
ASP0581_16580	COG4152	abc transporter atp-binding protein
ASP0581_16610	COG1940	carbohydrate kinase activity
ASP0581_16620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASP0581_16620	COG1263	PTS System
ASP0581_16620	COG2190	(PTS) system
ASP0581_16640	COG1621	beta-fructofuranosidase activity
ASP0581_16650	COG1609	Transcriptional regulator
ASP0581_16670	COG3425	synthase
ASP0581_16720	COG2815	serine threonine protein kinase
ASP0581_16720	COG0515	serine threonine protein kinase
ASP0581_16730	COG0631	protein serine/threonine phosphatase activity
ASP0581_16740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASP0581_16740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ASP0581_16760	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ASP0581_16770	COG1758	RNA polymerase activity
ASP0581_16780	COG0194	GDP metabolic process
ASP0581_16790	COG1418	mRNA catabolic process
ASP0581_16790	COG3599	regulation of cell shape
ASP0581_16800	COG4115	mRNA cleavage
ASP0581_16830	COG2226	methyltransferase
ASP0581_16840	COG0799	negative regulation of ribosome biogenesis
ASP0581_16860	COG1713	HD superfamily hydrolase involved in NAD metabolism
ASP0581_16870	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ASP0581_16880	COG1534	Rna-binding protein
ASP0581_16890	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ASP0581_16920	COG0668	transmembrane transport
ASP0581_16930	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ASP0581_16970	COG3118	belongs to the thioredoxin family
ASP0581_16980	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ASP0581_17000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ASP0581_17020	COG1164	Oligoendopeptidase f
ASP0581_17030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ASP0581_17160	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ASP0581_17170	COG1621	beta-fructofuranosidase activity
ASP0581_17180	COG1653	transport
ASP0581_17190	COG0395	ABC-type sugar transport system, permease component
ASP0581_17200	COG4209	transmembrane transport
ASP0581_17220	COG3711	transcriptional antiterminator
ASP0581_17230	COG2261	transglycosylase associated protein
ASP0581_17270	COG3237	CsbD-like
ASP0581_17300	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ASP0581_17320	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASP0581_17330	COG1447	Phosphotransferase system cellobiose-specific component IIA
ASP0581_17340	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASP0581_17360	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASP0581_17370	COG1940	carbohydrate kinase activity
ASP0581_17370	COG1846	Transcriptional regulator
ASP0581_17390	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ASP0581_17440	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASP0581_17450	COG0512	Glutamine amidotransferase of anthranilate synthase
ASP0581_17460	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASP0581_17490	COG1285	pathogenesis
ASP0581_17500	COG1178	ABC-type Fe3 transport system permease component
ASP0581_17560	COG5434	Belongs to the glycosyl hydrolase 28 family
ASP0581_17580	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ASP0581_17590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASP0581_17600	COG1132	(ABC) transporter
ASP0581_17610	COG1132	(ABC) transporter
ASP0581_17650	COG0708	Exodeoxyribonuclease III
ASP0581_17680	COG2233	PERMEase
ASP0581_17740	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ASP0581_17750	COG1609	Transcriptional regulator
ASP0581_17760	COG1063	alcohol dehydrogenase
ASP0581_17770	COG0789	Transcriptional regulator
ASP0581_17780	COG1230	cation diffusion facilitator family transporter
ASP0581_17800	COG3201	nicotinamide mononucleotide transporter
ASP0581_17810	COG1174	glycine betaine transport
ASP0581_17860	COG1363	Peptidase, m42
ASP0581_17880	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASP0581_17890	COG4605	iron ion homeostasis
ASP0581_17900	COG4604	ABC transporter, ATP-binding protein
ASP0581_17910	COG4607	ABC-type enterochelin transport system periplasmic component
ASP0581_17930	COG1187	pseudouridine synthase activity
ASP0581_17940	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ASP0581_17950	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ASP0581_17960	COG4974	Belongs to the 'phage' integrase family
ASP0581_17970	COG0517	IMP dehydrogenase activity
ASP0581_17990	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ASP0581_18000	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ASP0581_18010	COG3763	UPF0154 protein
ASP0581_18020	COG0366	Alpha amylase catalytic
ASP0581_18030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASP0581_18030	COG1263	PTS System
ASP0581_18040	COG2188	Transcriptional regulator
ASP0581_18080	COG4608	Belongs to the ABC transporter superfamily
ASP0581_18090	COG0444	Belongs to the ABC transporter superfamily
ASP0581_18100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASP0581_18110	COG0601	transmembrane transport
ASP0581_18120	COG4166	transmembrane transport
ASP0581_18140	COG0366	Alpha amylase catalytic
ASP0581_18150	COG0395	ABC-type sugar transport system, permease component
ASP0581_18160	COG1175	transmembrane transport
ASP0581_18170	COG1653	transport
ASP0581_18180	COG3345	alpha-galactosidase
ASP0581_18190	COG2207	Transcriptional regulator
ASP0581_18200	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ASP0581_18200	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ASP0581_18210	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASP0581_18230	COG3557	Belongs to the UPF0374 family
ASP0581_18290	COG0459	protein refolding
ASP0581_18320	COG4221	oxidoreductase activity
ASP0581_18330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASP0581_18340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASP0581_18400	COG1132	(ABC) transporter
ASP0581_18450	COG0217	transcriptional regulatory protein
ASP0581_18590	COG5632	N-Acetylmuramoyl-L-alanine amidase
ASP0581_18590	COG5263	repeat protein
ASP0581_18620	COG1058	Belongs to the CinA family
ASP0581_18620	COG1546	Belongs to the CinA family
ASP0581_18630	COG1316	TRANSCRIPTIONal
ASP0581_18650	COG0802	atpase or kinase
ASP0581_18710	COG0577	efflux transmembrane transporter activity
ASP0581_18710	COG1136	(ABC) transporter
ASP0581_18730	COG0105	UTP biosynthetic process
ASP0581_18750	COG0085	RNA polymerase activity
ASP0581_18760	COG1253	flavin adenine dinucleotide binding
ASP0581_18790	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ASP0581_18810	COG3480	Lon protease (S16) C-terminal proteolytic domain
ASP0581_18830	COG0742	ribosomal rna small subunit methyltransferase
ASP0581_18860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASP0581_18870	COG1254	Belongs to the acylphosphatase family
ASP0581_18880	COG0706	membrane insertase activity
ASP0581_18890	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ASP0581_18910	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ASP0581_18930	COG1322	Protein conserved in bacteria
ASP0581_18940	COG1564	THIamine pyrophosphokinase
ASP0581_18960	COG1162	GTPase activity
ASP0581_19040	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ASP0581_19050	COG0084	hydrolase, TatD family'
ASP0581_19070	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ASP0581_19080	COG0436	Aminotransferase
ASP0581_19100	COG0589	response to stress
ASP0581_19110	COG0561	phosphatase activity
ASP0581_19120	COG0252	asparaginase activity
ASP0581_19130	COG1609	Transcriptional regulator
ASP0581_19140	COG2197	response regulator
ASP0581_19150	COG4585	Histidine kinase
ASP0581_19160	COG0842	Transport permease protein
ASP0581_19170	COG1131	(ABC) transporter
ASP0581_19220	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ASP0581_19230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ASP0581_19240	COG0564	pseudouridine synthase activity
ASP0581_19260	COG0577	efflux transmembrane transporter activity
ASP0581_19280	COG0157	Belongs to the NadC ModD family
ASP0581_19300	COG4133	protoheme IX ABC transporter activity
ASP0581_19310	COG2188	Transcriptional regulator
ASP0581_19320	COG2723	6-phospho-beta-galactosidase activity
ASP0581_19330	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASP0581_19350	COG1447	Phosphotransferase system cellobiose-specific component IIA
ASP0581_19360	COG1012	belongs to the aldehyde dehydrogenase family
ASP0581_19360	COG1454	alcohol dehydrogenase
ASP0581_19380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASP0581_19400	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ASP0581_19440	COG3623	hexulose-6-phosphate isomerase
ASP0581_19460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASP0581_19480	COG3037	sugar-specific permease SgaT UlaA
ASP0581_19500	COG1847	R3H domain protein
ASP0581_19510	COG0706	membrane insertase activity
ASP0581_19520	COG0594	ribonuclease P activity
ASP0581_19600	COG4537	Required for transformation and DNA binding
ASP0581_19610	COG1459	type II secretion system
ASP0581_19620	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASP0581_19640	COG1063	alcohol dehydrogenase
ASP0581_19670	COG0343	queuine tRNA-ribosyltransferase activity
ASP0581_19690	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ASP0581_19700	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ASP0581_19710	COG3759	membrane
ASP0581_19740	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ASP0581_19740	COG0131	Imidazoleglycerol-phosphate dehydratase
ASP0581_19750	COG0534	Mate efflux family protein
ASP0581_19820	COG1674	ftsk spoiiie
ASP0581_19880	COG0582	viral genome integration into host DNA
ASP0581_19890	COG0582	viral genome integration into host DNA
ASP0581_19940	COG0166	Belongs to the GPI family
ASP0581_19960	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ASP0581_19970	COG1132	(ABC) transporter
ASP0581_20000	COG1132	(ABC) transporter
ASP0581_20020	COG1438	arginine binding
ASP0581_20060	COG0745	RESPONSE REGULATOR receiver
ASP0581_20070	COG5002	protein histidine kinase activity
ASP0581_20080	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ASP0581_20090	COG0573	inorganic phosphate transmembrane transporter activity
ASP0581_20110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASP0581_20120	COG0704	Plays a role in the regulation of phosphate uptake
ASP0581_20150	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ASP0581_20160	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ASP0581_20180	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ASP0581_20190	COG1473	amidohydrolase
ASP0581_20200	COG2171	N-acyltransferase activity
ASP0581_20210	COG0697	spore germination
ASP0581_20220	COG4499	WXG100 protein secretion system (Wss), protein YukC
ASP0581_20220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ASP0581_20240	COG2217	Heavy metal translocating P-type atpase
ASP0581_20260	COG2226	methyltransferase
ASP0581_20290	COG0058	SHG alpha-glucan phosphorylase activity
ASP0581_20300	COG1640	4-alpha-glucanotransferase
ASP0581_20310	COG2182	Extracellular solute-binding protein
ASP0581_20320	COG1175	transmembrane transport
ASP0581_20330	COG3833	ABC-type maltose transport systems, permease component
ASP0581_20340	COG5521	maltodextrose utilization protein MalA
ASP0581_20350	COG1609	Transcriptional regulator
ASP0581_20370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ASP0581_20440	COG1476	TRANSCRIPTIONal
ASP0581_20470	COG0124	histidyl-tRNA synthetase
ASP0581_20500	COG2151	metal-sulfur cluster biosynthetic enzyme
ASP0581_20530	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ASP0581_20540	COG3959	Transketolase, thiamine diphosphate binding domain
ASP0581_20570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASP0581_20600	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ASP0581_20690	COG0383	alpha-mannosidase activity
ASP0581_20710	COG3537	Alpha-1,2-mannosidase
ASP0581_20730	COG2235	arginine
ASP0581_20740	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ASP0581_20750	COG0549	Belongs to the carbamate kinase family
ASP0581_20760	COG1288	antiporter activity
ASP0581_20770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASP0581_20780	COG3583	domain protein
ASP0581_20780	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ASP0581_20790	COG3064	Membrane
ASP0581_20790	COG3583	domain protein
ASP0581_20790	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ASP0581_20820	COG1454	alcohol dehydrogenase
ASP0581_20830	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
ASP0581_20840	COG0235	Class ii aldolase
ASP0581_20900	COG1175	transmembrane transport
ASP0581_20910	COG1653	transport
ASP0581_20920	COG1070	Carbohydrate kinase
ASP0581_20930	COG1349	DNA-binding transcription factor activity
ASP0581_20950	COG3443	Belongs to the bacterial solute-binding protein 9 family
ASP0581_20950	COG0803	Belongs to the bacterial solute-binding protein 9 family
ASP0581_20960	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASP0581_20970	COG1121	(ABC) transporter
ASP0581_20980	COG1846	Transcriptional regulator
ASP0581_20990	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ASP0581_21000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASP0581_21010	COG1696	Membrane protein involved in D-alanine export
ASP0581_21030	COG2211	Major facilitator Superfamily
ASP0581_21040	COG3344	reverse transcriptase
ASP0581_21070	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ASP0581_21080	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ASP0581_21090	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ASP0581_21110	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ASP0581_21120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASP0581_21140	COG1755	Isoprenylcysteine carboxyl methyltransferase
ASP0581_21150	COG5002	protein histidine kinase activity
ASP0581_21160	COG0745	RESPONSE REGULATOR receiver
ASP0581_21170	COG0542	response to heat
ASP0581_21180	COG4463	regulation of RNA biosynthetic process
ASP0581_21190	COG1116	anion transmembrane transporter activity
ASP0581_21200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ASP0581_21210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASP0581_21250	COG0305	Participates in initiation and elongation during chromosome replication
ASP0581_21260	COG0359	binds to the 23S rRNA
ASP0581_21290	COG1040	competence protein
ASP0581_21300	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ASP0581_21310	COG1739	Uncharacterized protein family UPF0029
ASP0581_21340	COG3335	DDE superfamily endonuclease
ASP0581_21360	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ASP0581_21380	COG3942	CHAP domain
ASP0581_21390	COG1792	Involved in formation and maintenance of cell shape
ASP0581_21400	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ASP0581_21410	COG1122	ATPase activity
ASP0581_21420	COG1122	ATPase activity
ASP0581_21430	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ASP0581_21450	COG0612	Peptidase, M16
ASP0581_21460	COG0612	Peptidase, M16
ASP0581_21470	COG2501	S4 domain
ASP0581_21500	COG0180	Tryptophanyl-tRNA synthetase
ASP0581_21510	COG0488	(ABC) transporter
ASP0581_21540	COG1511	domain protein
ASP0581_21590	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ASP0581_21600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASP0581_21610	COG1475	DNA binding