locus-tag	class	description
MGAS9429_Spy0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
MGAS9429_Spy0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
MGAS9429_Spy0004	ENOG4105C3G	gtp-binding protein
MGAS9429_Spy0005	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
MGAS9429_Spy0006	ENOG4108JA2	transcriptioN-repair coupling factor
MGAS9429_Spy0007	ENOG41082I2	s4 domain protein
MGAS9429_Spy0013	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
MGAS9429_Spy0014	ENOG4105CUB	amino acid
MGAS9429_Spy0017	ENOG41068JE	domain protein
MGAS9429_Spy0018	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
MGAS9429_Spy0019	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
MGAS9429_Spy0020	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
MGAS9429_Spy0021	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
MGAS9429_Spy0023	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
MGAS9429_Spy0024	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
MGAS9429_Spy0026	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
MGAS9429_Spy0030	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
MGAS9429_Spy0034	ENOG4105C83	adenylosuccinate lyase
MGAS9429_Spy0037	ENOG4105KJF	protein tyrosine phosphatase
MGAS9429_Spy0040	ENOG4108EKI	Dehydrogenase
MGAS9429_Spy0042	ENOG4105UQX	Mate efflux family protein
MGAS9429_Spy0045	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
MGAS9429_Spy0046	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
MGAS9429_Spy0047	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MGAS9429_Spy0051	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
MGAS9429_Spy0056	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MGAS9429_Spy0057	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
MGAS9429_Spy0058	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
MGAS9429_Spy0059	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
MGAS9429_Spy0061	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
MGAS9429_Spy0062	ENOG4105VPB	50S ribosomal protein L30
MGAS9429_Spy0063	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
MGAS9429_Spy0064	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
MGAS9429_Spy0068	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MGAS9429_Spy0070	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
MGAS9429_Spy0078	ENOG4105FDK	ABC transporter
MGAS9429_Spy0082	ENOG4105BZ4	penicillin-binding protein
MGAS9429_Spy0084	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
MGAS9429_Spy0097	ENOG4105II7	pyrroline-5-carboxylate reductase
MGAS9429_Spy0098	ENOG4105CN9	Peptidase m42 family protein
MGAS9429_Spy0102	ENOG4108VDD	TRNA binding domain protein
MGAS9429_Spy0104	ENOG4105ZMH	deoxynucleoside kinase
MGAS9429_Spy0105	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
MGAS9429_Spy0114	ENOG4105KFN	sortase, SrtB family
MGAS9429_Spy0119	ENOG4105CRW	Short chain fatty acid transporter
MGAS9429_Spy0121	ENOG4105CHU	acetyl-coa acetyltransferase
MGAS9429_Spy0122	ENOG4107QP7	CoA-transferase subunit A
MGAS9429_Spy0125	ENOG4105KME	endoribonuclease L-psp
MGAS9429_Spy0134	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
MGAS9429_Spy0139	ENOG4105DIH	basic membrane
MGAS9429_Spy0140	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
MGAS9429_Spy0148	ENOG4105C28	cystathionine
MGAS9429_Spy0150	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
MGAS9429_Spy0154	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
MGAS9429_Spy0159	ENOG4108IJ7	Glycine betaine
MGAS9429_Spy0161	ENOG4105C2M	dna polymerase I
MGAS9429_Spy0163	ENOG4105G5W	regulator Fur family
MGAS9429_Spy0165	ENOG4105BZV	Phosphoadenosine phosphosulfate reductase
MGAS9429_Spy0166	ENOG4105GTN	ParB Domain Protein Nuclease
MGAS9429_Spy0168	ENOG4105DQ6	Transposase
MGAS9429_Spy0169	ENOG4105DQ6	Transposase
MGAS9429_Spy0172	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
MGAS9429_Spy0173	ENOG4105DQ6	Transposase
MGAS9429_Spy0179	ENOG41080Y5	BioY family
MGAS9429_Spy0180	ENOG410600T	transposase
MGAS9429_Spy0181	ENOG4108RQ5	Beta-lactamase domain-containing protein
MGAS9429_Spy0189	ENOG410600T	transposase
MGAS9429_Spy0193	ENOG4107ZXI	Rhomboid family
MGAS9429_Spy0195	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
MGAS9429_Spy0197	ENOG4105BZ1	(ABC) transporter
MGAS9429_Spy0198	ENOG4105BZ1	(ABC) transporter
MGAS9429_Spy0199	ENOG4105WPN	DNA integration recombination invertion protein
MGAS9429_Spy0200	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
MGAS9429_Spy0204	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
MGAS9429_Spy0212	ENOG4105VG0	50S ribosomal protein l34
MGAS9429_Spy0215	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
MGAS9429_Spy0216	ENOG4105DRS	transport system, permease
MGAS9429_Spy0221	ENOG4105F8V	Hydrolase, tatD family
MGAS9429_Spy0222	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
MGAS9429_Spy0224	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
MGAS9429_Spy0226	ENOG4105DJV	ribulose-phosphate 3-epimerase
MGAS9429_Spy0227	ENOG4105FJ0	thiamine
MGAS9429_Spy0228	ENOG4107QSV	RmuC domain protein
MGAS9429_Spy0229	ENOG4105EQI	Metal Dependent Phosphohydrolase
MGAS9429_Spy0230	ENOG4105DFT	pur operon repressor
MGAS9429_Spy0232	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
MGAS9429_Spy0234	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
MGAS9429_Spy0235	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
MGAS9429_Spy0237	ENOG4108JEH	abc transporter atp-binding protein
MGAS9429_Spy0238	ENOG4105E5Q	amino acid AbC transporter
MGAS9429_Spy0241	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MGAS9429_Spy0242	ENOG4105ESV	Glycosyl transferase, family 4
MGAS9429_Spy0245	ENOG4105JRK	feS assembly protein SufD
MGAS9429_Spy0246	ENOG4105C9B	Cysteine desulfurase
MGAS9429_Spy0247	ENOG4108UNV	SUF system FeS assembly protein, NifU family
MGAS9429_Spy0251	ENOG4105DIB	Oligopeptide-binding protein
MGAS9429_Spy0252	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
MGAS9429_Spy0253	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
MGAS9429_Spy0254	ENOG4105C3U	ABC transporter
MGAS9429_Spy0255	ENOG4108JQ7	(ABC) transporter
MGAS9429_Spy0259	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
MGAS9429_Spy0260	ENOG4105CQW	ribosome biogenesis GTPase YqeH
MGAS9429_Spy0261	ENOG410812S	Rna-binding protein
MGAS9429_Spy0263	ENOG4108WF2	Metal Dependent Phosphohydrolase
MGAS9429_Spy0264	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
MGAS9429_Spy0265	ENOG4105DXX	methyltransferase
MGAS9429_Spy0270	ENOG4105D01	(LipO)protein
MGAS9429_Spy0272	ENOG4108UMI	ABC transporter, permease
MGAS9429_Spy0275	ENOG4107ZYR	domain protein
MGAS9429_Spy0278	ENOG4108V0P	LemA family
MGAS9429_Spy0279	ENOG4105D0M	Protease HtpX homolog
MGAS9429_Spy0282	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
MGAS9429_Spy0284	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
MGAS9429_Spy0287	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
MGAS9429_Spy0288	ENOG4105C0D	helicase
MGAS9429_Spy0290	ENOG4105DFU	Cell wall formation (By similarity)
MGAS9429_Spy0293	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
MGAS9429_Spy0297	ENOG4108RWN	rrna methyltransferase
MGAS9429_Spy0309	ENOG4105FE9	pseudouridine synthase
MGAS9429_Spy0312	ENOG4108SAX	Membrane
MGAS9429_Spy0313	ENOG410841Q	phosphoesterase PA-phosphatase related protein
MGAS9429_Spy0314	ENOG4105N5T	Radical SAM Protein
MGAS9429_Spy0317	ENOG4105F1A	Pyruvate formate-lyase
MGAS9429_Spy0318	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
MGAS9429_Spy0320	ENOG4105EHG	Permease protein
MGAS9429_Spy0321	ENOG4105DQ5	transport system permease protein
MGAS9429_Spy0323	ENOG4105E0A	ABC, transporter
MGAS9429_Spy0326	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
MGAS9429_Spy0328	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
MGAS9429_Spy0330	ENOG410600T	transposase
MGAS9429_Spy0333	ENOG4105FA2	dna polymerase iii
MGAS9429_Spy0337	ENOG41063V3	Involved in initiation control of chromosome replication (By similarity)
MGAS9429_Spy0338	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
MGAS9429_Spy0341	ENOG41080E8	Transcriptional regulator, Spx MgsR family
MGAS9429_Spy0342	ENOG4105CGK	Exodeoxyribonuclease III
MGAS9429_Spy0362	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
MGAS9429_Spy0364	ENOG4105CXY	transporter
MGAS9429_Spy0366	ENOG4108YZ4	nudix hydrolase
MGAS9429_Spy0368	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
MGAS9429_Spy0371	ENOG4105DSE	periplasmic solute binding protein
MGAS9429_Spy0372	ENOG4105DIK	(ABC) transporter
MGAS9429_Spy0373	ENOG4105CC5	ABC transporter
MGAS9429_Spy0377	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
MGAS9429_Spy0379	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
MGAS9429_Spy0380	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
MGAS9429_Spy0381	ENOG4105QNR	S1 RNA binding domain protein
MGAS9429_Spy0386	ENOG4105C9A	Phoh family
MGAS9429_Spy0387	ENOG4108RG0	uracil-dna glycosylase
MGAS9429_Spy0388	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
MGAS9429_Spy0389	ENOG4107YR5	Diacylglycerol kinase
MGAS9429_Spy0393	ENOG4105D5G	Transposase
MGAS9429_Spy0409	ENOG4105D7A	ATP-binding protein
MGAS9429_Spy0410	ENOG4105C6X	Major Facilitator
MGAS9429_Spy0413	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
MGAS9429_Spy0419	ENOG4105CKK	Glycosyl transferase, family 2
MGAS9429_Spy0420	ENOG4108UYE	Lactoylglutathione lyase
MGAS9429_Spy0421	ENOG4108RCM	Nitroreductase
MGAS9429_Spy0422	ENOG4105DC7	peptidase M24
MGAS9429_Spy0423	ENOG4105ETE	Transcriptional regulator (LacI family
MGAS9429_Spy0424	ENOG4105W2C	Glycosyl transferase
MGAS9429_Spy0425	ENOG4105BZF	Glycosyl transferase (Group 1
MGAS9429_Spy0427	ENOG4108IUW	ABC transporter
MGAS9429_Spy0434	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
MGAS9429_Spy0435	ENOG4105BZU	Histidine kinase
MGAS9429_Spy0436	ENOG4105Q2H	domain protein
MGAS9429_Spy0437	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
MGAS9429_Spy0438	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
MGAS9429_Spy0440	ENOG4105E2X	shikimate dehydrogenase
MGAS9429_Spy0462	ENOG4108HCJ	Hydrolase
MGAS9429_Spy0463	ENOG410667J	hydrolase
MGAS9429_Spy0464	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MGAS9429_Spy0465	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
MGAS9429_Spy0466	ENOG4105CID	antiterminator
MGAS9429_Spy0467	ENOG4105C5Y	PTS System
MGAS9429_Spy0469	ENOG4108NNR	transporter substrate-binding protein
MGAS9429_Spy0470	ENOG4108PJD	permease
MGAS9429_Spy0475	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
MGAS9429_Spy0476	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
MGAS9429_Spy0481	ENOG4105CFP	Peptidase U32
MGAS9429_Spy0483	ENOG4105VEM	Conserved domain protein
MGAS9429_Spy0487	ENOG4108K79	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
MGAS9429_Spy0493	ENOG4108V06	Glutathione peroxidase
MGAS9429_Spy0494	ENOG4105DPN	Oligoendopeptidase f
MGAS9429_Spy0496	ENOG4105CNI	cell division protein FtsW
MGAS9429_Spy0499	ENOG4105CP7	Triose-phosphate isomerase
MGAS9429_Spy0506	ENOG4105DCI	Phosphohydrolase
MGAS9429_Spy0508	ENOG4108M60	Transcriptional regulator
MGAS9429_Spy0510	ENOG4105F3R	pts system mannose fructose sorbose family iid
MGAS9429_Spy0511	ENOG4105ETZ	PTS System
MGAS9429_Spy0512	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
MGAS9429_Spy0513	ENOG4105EP8	Glycosyl Hydrolase Family 88
MGAS9429_Spy0515	ENOG4105CHR	reductase
MGAS9429_Spy0518	ENOG4108RTU	Aldolase
MGAS9429_Spy0519	ENOG4107XGZ	Hydrolase
MGAS9429_Spy0520	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
MGAS9429_Spy0522	ENOG4105CAK	Cell division ATP-binding protein ftsE
MGAS9429_Spy0523	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
MGAS9429_Spy0525	ENOG4105CHR	reductase
MGAS9429_Spy0526	ENOG4105DVT	helicase
MGAS9429_Spy0527	ENOG4105CHM	Aminotransferase
MGAS9429_Spy0530	ENOG4105CHW	UPF0052 protein
MGAS9429_Spy0564	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
MGAS9429_Spy0573	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
MGAS9429_Spy0575	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
MGAS9429_Spy0592	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
MGAS9429_Spy0597	ENOG4105FDP	GntR family transcriptional regulator
MGAS9429_Spy0598	ENOG4105E70	isomerase
MGAS9429_Spy0599	ENOG41082DI	50s ribosomal protein l31
MGAS9429_Spy0600	ENOG4105SFS	phosphoesterase RecJ domain protein
MGAS9429_Spy0603	ENOG4107R4J	Chloride channel
MGAS9429_Spy0604	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
MGAS9429_Spy0620	ENOG4105CJ1	ABC, transporter
MGAS9429_Spy0626	ENOG410807C	QueT transporter
MGAS9429_Spy0628	ENOG4105CBD	Diacylglycerol kinase
MGAS9429_Spy0629	ENOG4105ZA1	atp synthase
MGAS9429_Spy0633	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
MGAS9429_Spy0634	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
MGAS9429_Spy0640	ENOG4105ZT7	DNA-entry nuclease
MGAS9429_Spy0642	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
MGAS9429_Spy0645	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
MGAS9429_Spy0646	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
MGAS9429_Spy0647	ENOG4105CGZ	zinc metallopeptidase
MGAS9429_Spy0650	ENOG4106PMH	Extracellular solute-binding protein family 3
MGAS9429_Spy0652	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
MGAS9429_Spy0653	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
MGAS9429_Spy0654	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
MGAS9429_Spy0655	ENOG4105VG1	fes assembly suf system protein
MGAS9429_Spy0656	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
MGAS9429_Spy0661	ENOG4105EY8	ABC transporter
MGAS9429_Spy0665	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
MGAS9429_Spy0673	ENOG4105CAT	Cytidine monophosphate kinase
MGAS9429_Spy0674	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
MGAS9429_Spy0675	ENOG4105VJV	50s ribosomal protein L35
MGAS9429_Spy0676	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
MGAS9429_Spy0678	ENOG4105DR4	Methyltransferase
MGAS9429_Spy0679	ENOG4105FF2	Type I DHQase
MGAS9429_Spy0680	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
MGAS9429_Spy0682	ENOG4105DC8	reductase
MGAS9429_Spy0683	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
MGAS9429_Spy0685	ENOG4105C3J	Cysteine desulfurase
MGAS9429_Spy0688	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
MGAS9429_Spy0690	ENOG4105K46	50S ribosomal protein l27
MGAS9429_Spy0691	ENOG4105CMU	LysR family (Transcriptional regulator
MGAS9429_Spy0693	ENOG4105C34	Pseudouridine synthase
MGAS9429_Spy0697	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
MGAS9429_Spy0699	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
MGAS9429_Spy0700	ENOG4107X8C	Efflux transporter RND family MFP subunit
MGAS9429_Spy0701	ENOG4105C19	ABC transporter
MGAS9429_Spy0702	ENOG4107RBB	ABC transporter, permease
MGAS9429_Spy0703	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
MGAS9429_Spy0704	ENOG4105K5M	30s ribosomal protein S16
MGAS9429_Spy0705	ENOG4105VB6	UPF0109 protein
MGAS9429_Spy0715	ENOG4105E98	transcriptional regulator DeoR family
MGAS9429_Spy0716	ENOG4105DE4	1-phosphofructokinase
MGAS9429_Spy0717	ENOG4105DM4	PTS System
MGAS9429_Spy0718	ENOG4107X35	defense response to bacterium
MGAS9429_Spy0719	ENOG4107X35	defense response to bacterium
MGAS9429_Spy0720	ENOG4105DQ6	Transposase
MGAS9429_Spy0725	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
MGAS9429_Spy0727	ENOG4105EPR	degv family
MGAS9429_Spy0729	ENOG4105C5H	ABC transporter
MGAS9429_Spy0732	ENOG4107YDN	peptide deformylase
MGAS9429_Spy0733	ENOG4105CGH	5'-nucleotidase
MGAS9429_Spy0735	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
MGAS9429_Spy0740	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
MGAS9429_Spy0743	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
MGAS9429_Spy0745	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
MGAS9429_Spy0757	ENOG4107RSM	transcriptional regulator
MGAS9429_Spy0762	ENOG4105E89	ABC transporter
MGAS9429_Spy0763	ENOG4105E5Q	amino acid AbC transporter
MGAS9429_Spy0764	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
MGAS9429_Spy0766	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
MGAS9429_Spy0767	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
MGAS9429_Spy0769	ENOG4105CM2	brancheD-chain amino acid aminotransferase
MGAS9429_Spy0771	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
MGAS9429_Spy0776	ENOG410600T	transposase
MGAS9429_Spy0780	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
MGAS9429_Spy0781	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
MGAS9429_Spy0782	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
MGAS9429_Spy0783	ENOG4108IXY	short-chain dehydrogenase reductase
MGAS9429_Spy0784	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
MGAS9429_Spy0785	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
MGAS9429_Spy0786	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
MGAS9429_Spy0788	ENOG4105CSM	endonuclease III
MGAS9429_Spy0790	ENOG4105EGD	dinuclear metal center protein, YbgI family
MGAS9429_Spy0791	ENOG4107VFR	oxidoreductase
MGAS9429_Spy0792	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
MGAS9429_Spy0794	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
MGAS9429_Spy0799	ENOG4105XB7	anti-repressor protein
MGAS9429_Spy0854	ENOG41068YB	TPR repeat-containing protein
MGAS9429_Spy0855	ENOG4105F23	Fibronectin-binding protein
MGAS9429_Spy0860	ENOG4105C2J	ABC transporter
MGAS9429_Spy0862	ENOG4107UWA	esterase
MGAS9429_Spy0864	ENOG4105C5H	ABC transporter
MGAS9429_Spy0865	ENOG4107RUY	(E1 component), alpha subunit
MGAS9429_Spy0866	ENOG4105CPP	Dehydrogenase, E1 component
MGAS9429_Spy0869	ENOG4107QN2	dihydrolipoyl dehydrogenase
MGAS9429_Spy0871	ENOG4106AM8	polysaccharide lyase family 8
MGAS9429_Spy0872	ENOG4105DF9	Lipoate-protein, ligase
MGAS9429_Spy0873	ENOG4105F1K	Glutamine amidotransferase
MGAS9429_Spy0874	ENOG4105DMS	mur ligase
MGAS9429_Spy0875	ENOG4105C8B	TIGR00159 family
MGAS9429_Spy0880	ENOG4105CSA	Coproporphyrinogen iii oxidase
MGAS9429_Spy0882	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
MGAS9429_Spy0890	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
MGAS9429_Spy0892	ENOG410600T	transposase
MGAS9429_Spy0899	ENOG4105ETZ	PTS System
MGAS9429_Spy0900	ENOG4105F3R	pts system mannose fructose sorbose family iid
MGAS9429_Spy0901	ENOG4105C2F	Histidine kinase
MGAS9429_Spy0902	ENOG4107VQW	regulatoR
MGAS9429_Spy0904	ENOG4105C26	Dehydrogenase
MGAS9429_Spy0907	ENOG4107QSE	Dipeptidase
MGAS9429_Spy0927	ENOG4105DA5	(ABC) transporter
MGAS9429_Spy0930	ENOG4108IMY	Transcriptional regulator
MGAS9429_Spy0939	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
MGAS9429_Spy0940	ENOG4105EUJ	GTP cyclohydrolase i
MGAS9429_Spy0941	ENOG4105EEI	dihydropteroate synthase
MGAS9429_Spy0942	ENOG4105KRF	dihydroneopterin aldolase
MGAS9429_Spy0943	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MGAS9429_Spy0946	ENOG4105F38	ABC transporter, permease
MGAS9429_Spy0947	ENOG4105D38	putrescine abc transporter
MGAS9429_Spy0948	ENOG4107RUE	extracellular solute-binding protein family 1
MGAS9429_Spy0949	ENOG4108MRH	transcriptional regulatory protein
MGAS9429_Spy0954	ENOG4105F0S	class B acid phosphatase
MGAS9429_Spy0955	ENOG4105CMQ	Chloride channel
MGAS9429_Spy0963	ENOG4105C3J	Cysteine desulfurase
MGAS9429_Spy0968	ENOG4108YBP	pseudouridine synthase
MGAS9429_Spy0969	ENOG4108IJ2	phosphate acetyltransferase
MGAS9429_Spy0970	ENOG4105EMU	Dehydrogenase
MGAS9429_Spy0973	ENOG4105E90	ABC transporter
MGAS9429_Spy0975	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
MGAS9429_Spy0981	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
MGAS9429_Spy0988	ENOG4105BZ1	(ABC) transporter
MGAS9429_Spy0989	ENOG4105BZ1	(ABC) transporter
MGAS9429_Spy0991	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
MGAS9429_Spy0993	ENOG4108Z6X	(sortase) family
MGAS9429_Spy0994	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
MGAS9429_Spy0998	ENOG4108UT2	hemolysin iii
MGAS9429_Spy1002	ENOG4105C79	DNA protecting protein DprA
MGAS9429_Spy1003	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
MGAS9429_Spy1007	ENOG4107RBM	d-lactate dehydrogenase
MGAS9429_Spy1011	ENOG4107QSA	Oxaloacetate decarboxylase
MGAS9429_Spy1012	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
MGAS9429_Spy1017	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MGAS9429_Spy1019	ENOG4105FDP	GntR family transcriptional regulator
MGAS9429_Spy1023	ENOG4105C5H	ABC transporter
MGAS9429_Spy1025	ENOG4105DWF	phosphomethylpyrimidine kinase
MGAS9429_Spy1028	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
MGAS9429_Spy1029	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
MGAS9429_Spy1030	ENOG4105CKU	formyltetrahydrofolate synthetase
MGAS9429_Spy1035	ENOG4105DEN	Luciferase family
MGAS9429_Spy1037	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
MGAS9429_Spy1039	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
MGAS9429_Spy1040	ENOG4105FH5	Membrane
MGAS9429_Spy1043	ENOG4105UIB	(ABC) transporter
MGAS9429_Spy1044	ENOG4108JQ9	ABC transporter
MGAS9429_Spy1045	ENOG4105DIH	basic membrane
MGAS9429_Spy1046	ENOG4105KG3	cytidine deaminase
MGAS9429_Spy1047	ENOG4107Y49	methyltransferase
MGAS9429_Spy1050	ENOG4105US7	Histidine kinase
MGAS9429_Spy1051	ENOG4108STX	response regulator
MGAS9429_Spy1054	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
MGAS9429_Spy1056	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
MGAS9429_Spy1057	ENOG4105E2Z	phosphate ABC transporter (Permease
MGAS9429_Spy1058	ENOG4105C8U	phosphate abc transporter
MGAS9429_Spy1059	ENOG4105CVA	phosphate
MGAS9429_Spy1060	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
MGAS9429_Spy1061	ENOG4105ECY	inositol monophosphatase
MGAS9429_Spy1064	ENOG4105DTN	riboflavin biosynthesis protein ribF
MGAS9429_Spy1065	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
MGAS9429_Spy1070	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
MGAS9429_Spy1074	ENOG4105VBF	alkaline shock protein
MGAS9429_Spy1076	ENOG4105VBF	alkaline shock protein
MGAS9429_Spy1082	ENOG4105BZG	amino acid carrier protein
MGAS9429_Spy1086	ENOG4106TNF	Periplasmic binding protein
MGAS9429_Spy1087	ENOG4105CDA	abc transporter atp-binding protein
MGAS9429_Spy1088	ENOG4105E5Q	amino acid AbC transporter
MGAS9429_Spy1089	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
MGAS9429_Spy1090	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
MGAS9429_Spy1092	ENOG4105CA9	Pyruvate kinase
MGAS9429_Spy1094	ENOG4105C0B	DNA polymerase III (alpha subunit)
MGAS9429_Spy1095	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
MGAS9429_Spy1096	ENOG4105CZV	ABC transporter
MGAS9429_Spy1101	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
MGAS9429_Spy1102	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
MGAS9429_Spy1103	ENOG4105FKQ	transcriptional regulator
MGAS9429_Spy1104	ENOG4107FKK	extracellular solute-binding protein family 1
MGAS9429_Spy1106	ENOG4105EG2	ABC transporter, permease
MGAS9429_Spy1112	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
MGAS9429_Spy1114	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
MGAS9429_Spy1115	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
MGAS9429_Spy1118	ENOG4107R0W	ABC transporter
MGAS9429_Spy1119	ENOG4105CDA	abc transporter atp-binding protein
MGAS9429_Spy1122	ENOG4105CK1	PTS System
MGAS9429_Spy1124	ENOG4105VCP	PTS System
MGAS9429_Spy1126	ENOG4105EMD	TRANSCRIPTIONal
MGAS9429_Spy1128	ENOG4105CS2	ec 3.2.1.21
MGAS9429_Spy1134	ENOG4105DQ6	Transposase
MGAS9429_Spy1137	ENOG4107RGD	Major Facilitator superfamily
MGAS9429_Spy1149	ENOG4105D9U	N-acetyltransferase
MGAS9429_Spy1151	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
MGAS9429_Spy1154	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
MGAS9429_Spy1157	ENOG410600T	transposase
MGAS9429_Spy1159	ENOG4105C6E	dna polymerase iii
MGAS9429_Spy1160	ENOG4108ZGC	gaf domain protein
MGAS9429_Spy1164	ENOG4105FDU	atp-dependent rna helicase
MGAS9429_Spy1165	ENOG4108ZJ4	polysaccharide deacetylase
MGAS9429_Spy1166	ENOG4105C26	Dehydrogenase
MGAS9429_Spy1167	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
MGAS9429_Spy1168	ENOG4105KRI	phosphocarrier protein (HPr
MGAS9429_Spy1169	ENOG41067VN	Glutaredoxin
MGAS9429_Spy1170	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
MGAS9429_Spy1171	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
MGAS9429_Spy1174	ENOG4105DQ6	Transposase
MGAS9429_Spy1175	ENOG4105DQ6	Transposase
MGAS9429_Spy1178	ENOG4105VZ8	Transcriptional regulator
MGAS9429_Spy1181	ENOG4108VQJ	O-methyltransferase
MGAS9429_Spy1182	ENOG4105FCD	Major Facilitator
MGAS9429_Spy1194	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
MGAS9429_Spy1195	ENOG4105KQC	Competence protein
MGAS9429_Spy1196	ENOG41060K3	Methyltransferase
MGAS9429_Spy1197	ENOG4105F6E	Acyl-transferase
MGAS9429_Spy1200	ENOG4105C1J	atp-dependent rna helicase
MGAS9429_Spy1202	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
MGAS9429_Spy1204	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
MGAS9429_Spy1205	ENOG4105CPF	Cell wall formation (By similarity)
MGAS9429_Spy1206	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
MGAS9429_Spy1208	ENOG4105TMB	Formate nitrite transporter
MGAS9429_Spy1209	ENOG4105RNB	
MGAS9429_Spy1212	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
MGAS9429_Spy1214	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
MGAS9429_Spy1216	ENOG4105C59	p-type ATPase
MGAS9429_Spy1217	ENOG4105K70	DNA-binding protein
MGAS9429_Spy1219	ENOG41090WU	lipolytic protein G-D-S-L family
MGAS9429_Spy1222	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
MGAS9429_Spy1223	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
MGAS9429_Spy1224	ENOG4105DX0	Hemolysin A
MGAS9429_Spy1226	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
MGAS9429_Spy1231	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
MGAS9429_Spy1233	ENOG4105E5Q	amino acid AbC transporter
MGAS9429_Spy1234	ENOG4107IN1	Protein of unknown function (DUF1797)
MGAS9429_Spy1235	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
MGAS9429_Spy1236	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
MGAS9429_Spy1239	ENOG4105MMF	Cell division protein DIVIVA
MGAS9429_Spy1240	ENOG4105DBK	s4 domain protein
MGAS9429_Spy1243	ENOG4105DFA	alanine racemase domain protein
MGAS9429_Spy1250	ENOG4105CI3	gtp-binding protein typa
MGAS9429_Spy1251	ENOG4107YZP	Rhodanese domain protein
MGAS9429_Spy1252	ENOG4105DKQ	ROK family
MGAS9429_Spy1254	ENOG4105HUF	DNA protection during starvation protein
MGAS9429_Spy1257	ENOG4105MMD	transcriptional regulator
MGAS9429_Spy1259	ENOG4105ETE	Transcriptional regulator (LacI family
MGAS9429_Spy1260	ENOG41063PX	domain protein
MGAS9429_Spy1261	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
MGAS9429_Spy1262	ENOG4106H78	methyltransferase
MGAS9429_Spy1264	ENOG4105C5B	carbamate kinase
MGAS9429_Spy1265	ENOG4107QSE	Dipeptidase
MGAS9429_Spy1266	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
MGAS9429_Spy1267	ENOG4105DBV	ornithine carbamoyltransferase
MGAS9429_Spy1269	ENOG4105CEU	Arginine dihydrolase
MGAS9429_Spy1271	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
MGAS9429_Spy1274	ENOG4105C2F	Histidine kinase
MGAS9429_Spy1275	ENOG4107VQW	regulatoR
MGAS9429_Spy1276	ENOG4105E0X	reductase
MGAS9429_Spy1277	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MGAS9429_Spy1278	ENOG4107QIV	Cytochrome c biogenesis protein
MGAS9429_Spy1279	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
MGAS9429_Spy1280	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
MGAS9429_Spy1291	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
MGAS9429_Spy1296	ENOG4105DVA	methyltransferase
MGAS9429_Spy1297	ENOG4105E2X	shikimate dehydrogenase
MGAS9429_Spy1298	ENOG4105CNT	hydrolase family 2
MGAS9429_Spy1299	ENOG4105EQD	regulatoR
MGAS9429_Spy1300	ENOG4105C2F	Histidine kinase
MGAS9429_Spy1303	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
MGAS9429_Spy1304	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
MGAS9429_Spy1307	ENOG4105CS2	ec 3.2.1.21
MGAS9429_Spy1308	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
MGAS9429_Spy1311	ENOG4105C8I	hydrolase, family 38
MGAS9429_Spy1323	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
MGAS9429_Spy1327	ENOG4105WH1	Two component transcriptional regulator luxr family
MGAS9429_Spy1328	ENOG4105ENE	Histidine kinase
MGAS9429_Spy1330	ENOG4105D9P	serine threonine protein kinase
MGAS9429_Spy1332	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
MGAS9429_Spy1334	ENOG4105C25	Primosomal protein n'
MGAS9429_Spy1338	ENOG4105CMU	LysR family (Transcriptional regulator
MGAS9429_Spy1339	ENOG4105CHU	acetyl-coa acetyltransferase
MGAS9429_Spy1340	ENOG4107QP7	CoA-transferase subunit A
MGAS9429_Spy1342	ENOG4105DTD	Dehydrogenase
MGAS9429_Spy1343	ENOG4105CY2	Citrate transporter
MGAS9429_Spy1344	ENOG4105CY2	Citrate transporter
MGAS9429_Spy1345	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
MGAS9429_Spy1346	ENOG41070VT	
MGAS9429_Spy1347	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
MGAS9429_Spy1348	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
MGAS9429_Spy1351	ENOG4105BZ4	penicillin-binding protein
MGAS9429_Spy1352	ENOG4105CTZ	aminopeptidase c
MGAS9429_Spy1354	ENOG4105DAP	Nicotinate phosphoribosyltransferase
MGAS9429_Spy1355	ENOG4105C85	amino acid
MGAS9429_Spy1356	ENOG4105C3M	thioredoxin reductase
MGAS9429_Spy1358	ENOG4105CDA	abc transporter atp-binding protein
MGAS9429_Spy1359	ENOG4105E5Q	amino acid AbC transporter
MGAS9429_Spy1361	ENOG4105C1J	atp-dependent rna helicase
MGAS9429_Spy1362	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
MGAS9429_Spy1363	ENOG4105CJN	penicillin-binding protein
MGAS9429_Spy1365	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
MGAS9429_Spy1374	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
MGAS9429_Spy1376	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
MGAS9429_Spy1377	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
MGAS9429_Spy1378	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
MGAS9429_Spy1379	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
MGAS9429_Spy1385	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
MGAS9429_Spy1388	ENOG4105CE4	GlcNAc 6-P deacetylase
MGAS9429_Spy1394	ENOG410667J	hydrolase
MGAS9429_Spy1395	ENOG4105EN6	Membrane
MGAS9429_Spy1398	ENOG4105DE4	1-phosphofructokinase
MGAS9429_Spy1407	ENOG4105C59	p-type ATPase
MGAS9429_Spy1408	ENOG4105NA0	Transcriptional regulator
MGAS9429_Spy1410	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
MGAS9429_Spy1411	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
MGAS9429_Spy1413	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
MGAS9429_Spy1414	ENOG4105CHV	Transcription elongation factor NusA
MGAS9429_Spy1415	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
MGAS9429_Spy1418	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
MGAS9429_Spy1442	ENOG4105IG6	Phage terminase, large subunit
MGAS9429_Spy1469	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
MGAS9429_Spy1470	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
MGAS9429_Spy1474	ENOG4105K59	histidine triad (HIT) protein
MGAS9429_Spy1476	ENOG4108KGH	TRANSCRIPTIONal
MGAS9429_Spy1478	ENOG4105K8N	protein family UPF0079, ATPase
MGAS9429_Spy1479	ENOG4105C7N	Xanthine uracil vitamin C permease
MGAS9429_Spy1480	ENOG4108KP7	hydrolase
MGAS9429_Spy1482	ENOG4105ETZ	PTS System
MGAS9429_Spy1483	ENOG4105F3R	pts system mannose fructose sorbose family iid
MGAS9429_Spy1487	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
MGAS9429_Spy1488	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
MGAS9429_Spy1491	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
MGAS9429_Spy1492	ENOG4105CHR	reductase
MGAS9429_Spy1493	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
MGAS9429_Spy1495	ENOG410854A	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
MGAS9429_Spy1498	ENOG4105CGU	Enoyl-CoA hydratase
MGAS9429_Spy1499	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
MGAS9429_Spy1501	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MGAS9429_Spy1502	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
MGAS9429_Spy1505	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
MGAS9429_Spy1506	ENOG4107BMA	Transglycosylase associated protein
MGAS9429_Spy1510	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
MGAS9429_Spy1511	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
MGAS9429_Spy1513	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
MGAS9429_Spy1514	ENOG4105CHM	Aminotransferase
MGAS9429_Spy1517	ENOG4107RB3	L-asparaginase
MGAS9429_Spy1521	ENOG4105CB5	ATP-dependent DNA helicase recG
MGAS9429_Spy1524	ENOG4108JJB	ABC transporter
MGAS9429_Spy1527	ENOG4105BZ1	(ABC) transporter
MGAS9429_Spy1528	ENOG4108JJ9	ABC, transporter
MGAS9429_Spy1529	ENOG4105E0A	ABC, transporter
MGAS9429_Spy1530	ENOG4108HWH	(ABC) transporter
MGAS9429_Spy1535	ENOG41068JE	domain protein
MGAS9429_Spy1539	ENOG410600T	transposase
MGAS9429_Spy1541	ENOG4105DG6	mannose-6-phosphate isomerase
MGAS9429_Spy1543	ENOG4105EVU	fructokinase
MGAS9429_Spy1546	ENOG4105C5Y	PTS System
MGAS9429_Spy1548	ENOG4105ETE	Transcriptional regulator (LacI family
MGAS9429_Spy1551	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
MGAS9429_Spy1552	ENOG4108UK2	deaminase
MGAS9429_Spy1553	ENOG4105DC7	peptidase M24
MGAS9429_Spy1560	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
MGAS9429_Spy1562	ENOG4105CEN	a g-specific adenine glycosylase
MGAS9429_Spy1564	ENOG4105K63	Thioredoxin
MGAS9429_Spy1566	ENOG4105C98	muts2 protein
MGAS9429_Spy1570	ENOG4105C3F	Signal peptidase i
MGAS9429_Spy1571	ENOG4105C7H	Helicase, RecD TraA family
MGAS9429_Spy1574	ENOG4105C6N	Formate acetyltransferase
MGAS9429_Spy1575	ENOG4107S1E	Beta-lactamase
MGAS9429_Spy1578	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
MGAS9429_Spy1580	ENOG4105CZM	Major Facilitator
MGAS9429_Spy1581	ENOG4105TV1	Transcriptional regulator
MGAS9429_Spy1586	ENOG4107TXC	Transcriptional regulator
MGAS9429_Spy1587	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
MGAS9429_Spy1589	ENOG4105CBX	hi0933 family
MGAS9429_Spy1591	ENOG4105D9N	nucleoside
MGAS9429_Spy1592	ENOG4108I5U	Uridine phosphorylase
MGAS9429_Spy1595	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
MGAS9429_Spy1596	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
MGAS9429_Spy1597	ENOG410801F	ribosomal-protein-alanine acetyltransferase
MGAS9429_Spy1598	ENOG41072GX	Peptidase M22 Glycoprotease
MGAS9429_Spy1601	ENOG4105C5F	glutamine synthetase
MGAS9429_Spy1602	ENOG4105KV4	Transcriptional regulator
MGAS9429_Spy1604	ENOG4105BZA	Phosphoglycerate kinase
MGAS9429_Spy1605	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
MGAS9429_Spy1610	ENOG4105D2N	Aldolase
MGAS9429_Spy1613	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
MGAS9429_Spy1614	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
MGAS9429_Spy1616	ENOG4105D8X	mechanosensitive ion channel
MGAS9429_Spy1618	ENOG4105PUK	Membrane
MGAS9429_Spy1619	ENOG4105DWF	phosphomethylpyrimidine kinase
MGAS9429_Spy1620	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
MGAS9429_Spy1623	ENOG4105BZW	Glycerate kinase
MGAS9429_Spy1624	ENOG4105DZR	Type I site-specific deoxyribonuclease
MGAS9429_Spy1628	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
MGAS9429_Spy1631	ENOG4105C19	ABC transporter
MGAS9429_Spy1632	ENOG4105BZ1	(ABC) transporter
MGAS9429_Spy1636	ENOG4105CK1	PTS System
MGAS9429_Spy1637	ENOG4105VCP	PTS System
MGAS9429_Spy1640	ENOG41083K5	isomerase
MGAS9429_Spy1648	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
MGAS9429_Spy1653	ENOG4105C2N	RNA methyltransferase TrmH family group 3
MGAS9429_Spy1655	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MGAS9429_Spy1659	ENOG4105D7W	serine acetyltransferase
MGAS9429_Spy1662	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
MGAS9429_Spy1665	ENOG4105ETD	TRANSCRIPTIONal
MGAS9429_Spy1670	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
MGAS9429_Spy1671	ENOG4108YYH	Nadph-dependent fmn reductase
MGAS9429_Spy1676	ENOG4105KNE	Phosphatidate cytidylyltransferase
MGAS9429_Spy1677	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
MGAS9429_Spy1679	ENOG4105VIE	preprotein translocase, subunit YajC
MGAS9429_Spy1681	ENOG4108IUM	Glycogen debranching enzyme
MGAS9429_Spy1685	ENOG4108IJ9	(ABC) transporter
MGAS9429_Spy1693	ENOG4105CI1	PTS System
MGAS9429_Spy1694	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
MGAS9429_Spy1702	ENOG4105CRQ	synthase (Component I)
MGAS9429_Spy1703	ENOG4105DDQ	anthranilate synthase
MGAS9429_Spy1704	ENOG4105D1H	recombination factor protein RarA
MGAS9429_Spy1713	ENOG4108JJB	ABC transporter
MGAS9429_Spy1717	ENOG4105DSE	periplasmic solute binding protein
MGAS9429_Spy1718	ENOG410600T	transposase
MGAS9429_Spy1720	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
MGAS9429_Spy1728	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
MGAS9429_Spy1729	ENOG4105BZU	Histidine kinase
MGAS9429_Spy1730	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
MGAS9429_Spy1731	ENOG4107RBB	ABC transporter, permease
MGAS9429_Spy1732	ENOG4105C19	ABC transporter
MGAS9429_Spy1749	ENOG4108W5N	phosphatidylglycerophosphatase a
MGAS9429_Spy1752	ENOG4105C6N	Formate acetyltransferase
MGAS9429_Spy1753	ENOG4105C6N	Formate acetyltransferase
MGAS9429_Spy1754	ENOG4105CK1	PTS System
MGAS9429_Spy1755	ENOG4105VZJ	PTS System
MGAS9429_Spy1756	ENOG4105VCP	PTS System
MGAS9429_Spy1757	ENOG4107RHR	regulatoR
MGAS9429_Spy1758	ENOG4105E98	transcriptional regulator DeoR family
MGAS9429_Spy1759	ENOG4105F1A	Pyruvate formate-lyase
MGAS9429_Spy1763	ENOG4105BZ4	penicillin-binding protein
MGAS9429_Spy1766	ENOG4108YBP	pseudouridine synthase
MGAS9429_Spy1773	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
MGAS9429_Spy1774	ENOG4105KEX	transcriptional regulator, ctsr
MGAS9429_Spy1776	ENOG4105VEQ	Cold shock protein
MGAS9429_Spy1778	ENOG4105D3R	alkyl hydroperoxide reductase
MGAS9429_Spy1782	ENOG4105CGP	Urocanate hydratase
MGAS9429_Spy1783	ENOG4105CCS	Glutamate formiminotransferase
MGAS9429_Spy1784	ENOG410908R	Methenyltetrahydrofolate cyclohydrolase
MGAS9429_Spy1787	ENOG4107R7I	amino acid
MGAS9429_Spy1791	ENOG4105CE9	30S ribosomal protein S2
MGAS9429_Spy1793	ENOG4105C9K	Endothelin-converting enzyme 1
MGAS9429_Spy1794	ENOG4105CG3	alpha amylase, catalytic region
MGAS9429_Spy1795	ENOG4105C5Y	PTS System
MGAS9429_Spy1796	ENOG4107414	GntR family transcriptional regulator
MGAS9429_Spy1797	ENOG4105KVH	Transcriptional regulator
MGAS9429_Spy1798	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
MGAS9429_Spy1800	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
MGAS9429_Spy1802	ENOG4105EP9	oxidoreductase
MGAS9429_Spy1804	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
MGAS9429_Spy1809	ENOG410888K	transcriptional regulator, Spx
MGAS9429_Spy1812	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
MGAS9429_Spy1814	ENOG4105D94	Major Facilitator Superfamily
MGAS9429_Spy1818	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
MGAS9429_Spy1819	ENOG4105C75	arginyL-tRNA synthetase
MGAS9429_Spy1821	ENOG4108JYZ	YitT family
MGAS9429_Spy1822	ENOG4108JYZ	YitT family
MGAS9429_Spy1823	ENOG4107AYK	membrAne
MGAS9429_Spy1842	ENOG4105ECB	domain protein
MGAS9429_Spy1844	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
MGAS9429_Spy1846	ENOG4105CDU	Replicative dna helicase
MGAS9429_Spy1847	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
MGAS9429_Spy1853	ENOG4105EJQ	L-serine dehydratase
MGAS9429_Spy1854	ENOG4106770	Is able to cleave peptidoglycan (By similarity)
MGAS9429_Spy1855	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
MGAS9429_Spy1856	ENOG4108JJB	ABC transporter
MGAS9429_Spy1857	ENOG4108JJB	ABC transporter
MGAS9429_Spy1858	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
MGAS9429_Spy1864	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
MGAS9429_Spy1868	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
MGAS9429_Spy1872	ENOG4105C5H	ABC transporter
MGAS9429_Spy1877	ENOG4105C0H	protease
MGAS9429_Spy1878	ENOG4105FA0	parb-like partition protein