locus-tag	class	description
IM697_00015	COG0640	Transcriptional regulator
IM697_00035	COG2255	four-way junction helicase activity
IM697_00050	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IM697_00065	COG5002	protein histidine kinase activity
IM697_00070	COG0745	RESPONSE REGULATOR receiver
IM697_00105	COG0714	Associated with various cellular activities
IM697_00135	COG0667	Aldo Keto reductase
IM697_00155	COG2264	protein methyltransferase activity
IM697_00170	COG0248	Ppx GppA phosphatase
IM697_00175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_00195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM697_00235	COG2188	Transcriptional regulator
IM697_00280	COG2409	Drug exporters of the RND superfamily
IM697_00285	COG4585	Histidine kinase
IM697_00305	COG0714	Associated with various cellular activities
IM697_00350	COG1132	(ABC) transporter
IM697_00365	COG0482	sulfurtransferase activity
IM697_00405	COG0366	Alpha amylase catalytic
IM697_00420	COG1957	nucleoside hydrolase
IM697_00425	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IM697_00435	COG0701	Predicted permease
IM697_00450	COG0222	ribosome binding
IM697_00465	COG4249	Peptidase C14 caspase catalytic subunit p20
IM697_00465	COG2319	Wd-40 repeat
IM697_00515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM697_00520	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IM697_00555	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IM697_00560	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IM697_00575	COG1289	transmembrane transporter activity
IM697_00585	COG0583	DNA-binding transcription factor activity
IM697_00600	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM697_00655	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IM697_00670	COG1741	Belongs to the pirin family
IM697_00675	COG0477	Major facilitator Superfamily
IM697_00695	COG1960	acyl-CoA dehydrogenase activity
IM697_00700	COG1362	aminopeptidase activity
IM697_00750	COG2271	Major facilitator Superfamily
IM697_00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
IM697_00770	COG0022	dehydrogenase e1 component
IM697_00780	COG0515	serine threonine protein kinase
IM697_00785	COG0515	serine threonine protein kinase
IM697_00805	COG3321	synthase
IM697_00805	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_00805	COG0604	alcohol dehydrogenase
IM697_00820	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IM697_00850	COG1522	sequence-specific DNA binding
IM697_00855	COG1309	transcriptional regulator
IM697_00860	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM697_00885	COG1960	acyl-CoA dehydrogenase activity
IM697_00905	COG1733	regulation of RNA biosynthetic process
IM697_00910	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IM697_00925	COG4249	Peptidase C14 caspase catalytic subunit p20
IM697_00925	COG2319	Wd-40 repeat
IM697_00935	COG0438	transferase activity, transferring glycosyl groups
IM697_00955	COG1716	ATPase activity
IM697_00960	COG1716	ATPase activity
IM697_00975	COG0768	penicillin binding
IM697_00980	COG0515	serine threonine protein kinase
IM697_00995	COG3764	Sortase (surface protein transpeptidase)
IM697_01000	COG3764	Sortase (surface protein transpeptidase)
IM697_01015	COG3764	Sortase (surface protein transpeptidase)
IM697_01030	COG0705	Rhomboid family
IM697_01055	COG0515	serine threonine protein kinase
IM697_01075	COG1116	anion transmembrane transporter activity
IM697_01090	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IM697_01095	COG0187	DNA topoisomerase II activity
IM697_01100	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
IM697_01105	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IM697_01110	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IM697_01115	COG0592	DNA-directed DNA polymerase activity
IM697_01120	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IM697_01125	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IM697_01130	COG0594	ribonuclease P activity
IM697_01135	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IM697_01140	COG0706	membrane insertase activity
IM697_01150	COG0357	Ribosomal RNA small subunit methyltransferase G
IM697_01155	COG1192	Involved in chromosome partitioning
IM697_01170	COG3118	belongs to the thioredoxin family
IM697_01175	COG0492	ferredoxin-NADP+ reductase activity
IM697_01185	COG1595	DNA-templated transcription, initiation
IM697_01190	COG0515	serine threonine protein kinase
IM697_01190	COG2815	serine threonine protein kinase
IM697_01205	COG0617	tRNA 3'-terminal CCA addition
IM697_01230	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IM697_01255	COG0360	Binds together with S18 to 16S ribosomal RNA
IM697_01260	COG0629	single-stranded DNA binding
IM697_01265	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IM697_01270	COG0359	binds to the 23S rRNA
IM697_01280	COG0305	Participates in initiation and elongation during chromosome replication
IM697_01290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM697_01305	COG2814	Major facilitator Superfamily
IM697_01340	COG0626	cystathionine gamma-synthase activity
IM697_01345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IM697_01350	COG1950	PFAM Membrane protein of
IM697_01355	COG0662	Cupin 2, conserved barrel domain protein
IM697_01380	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IM697_01395	COG1609	Transcriptional regulator
IM697_01400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IM697_01410	COG1271	oxidase subunit
IM697_01415	COG1294	oxidase, subunit
IM697_01420	COG4988	ABC transporter
IM697_01430	COG0561	phosphatase activity
IM697_01445	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
IM697_01450	COG0789	Transcriptional regulator
IM697_01495	COG0561	phosphatase activity
IM697_01500	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IM697_01510	COG2837	iron assimilation
IM697_01525	COG1999	signal sequence binding
IM697_01560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM697_01565	COG0006	proline dipeptidase activity
IM697_01585	COG0653	protein targeting
IM697_01600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM697_01680	COG3328	transposase activity
IM697_01725	COG1595	DNA-templated transcription, initiation
IM697_01730	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_01735	COG0784	Response regulator, receiver
IM697_01760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_01765	COG1335	isochorismatase
IM697_01770	COG0431	NADPH-dependent FMN reductase
IM697_01780	COG1733	regulation of RNA biosynthetic process
IM697_01785	COG1846	Transcriptional regulator
IM697_01815	COG0745	RESPONSE REGULATOR receiver
IM697_01820	COG2205	protein histidine kinase activity
IM697_01830	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IM697_01835	COG0477	Major facilitator Superfamily
IM697_01845	COG3467	pyridoxamine 5'-phosphate
IM697_01850	COG2353	YceI-like domain
IM697_01855	COG0477	Major facilitator Superfamily
IM697_01875	COG1191	sigma factor activity
IM697_01880	COG1191	sigma factor activity
IM697_01915	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IM697_01985	COG1725	Transcriptional regulator
IM697_02000	COG3328	transposase activity
IM697_02040	COG0395	ABC-type sugar transport system, permease component
IM697_02045	COG3345	alpha-galactosidase
IM697_02055	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IM697_02060	COG3896	Chloramphenicol phosphotransferase-like protein
IM697_02075	COG0438	transferase activity, transferring glycosyl groups
IM697_02080	COG0438	transferase activity, transferring glycosyl groups
IM697_02100	COG1131	(ABC) transporter
IM697_02145	COG2188	Transcriptional regulator
IM697_02155	COG2188	Transcriptional regulator
IM697_02225	COG0151	Belongs to the GarS family
IM697_02240	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IM697_02250	COG2197	response regulator
IM697_02285	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IM697_02290	COG0047	phosphoribosylformylglycinamidine synthase activity
IM697_02295	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IM697_02320	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IM697_02355	COG1643	Atp-dependent helicase
IM697_02390	COG0513	Belongs to the DEAD box helicase family
IM697_02405	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IM697_02415	COG1733	regulation of RNA biosynthetic process
IM697_02420	COG0667	Aldo Keto reductase
IM697_02425	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_02430	COG1309	transcriptional regulator
IM697_02445	COG2226	methyltransferase
IM697_02465	COG0179	Fumarylacetoacetate (FAA) hydrolase
IM697_02470	COG2814	Major facilitator Superfamily
IM697_02480	COG1309	transcriptional regulator
IM697_02525	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IM697_02535	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IM697_02535	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IM697_02565	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IM697_02570	COG0579	oxidoreductase
IM697_02590	COG1131	(ABC) transporter
IM697_02625	COG1252	NADH dehydrogenase
IM697_02660	COG2197	response regulator
IM697_02665	COG4585	Histidine kinase
IM697_02705	COG1846	Transcriptional regulator
IM697_02720	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_02730	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IM697_02745	COG0739	heme binding
IM697_02745	COG0741	lytic transglycosylase activity
IM697_02745	COG1196	nuclear chromosome segregation
IM697_02750	COG0671	phosphoesterase, PA-phosphatase related
IM697_02755	COG3415	Transposase
IM697_02755	COG2801	Transposase and inactivated derivatives
IM697_02770	COG0277	FAD linked oxidase domain protein
IM697_02775	COG0306	phosphate transporter
IM697_02785	COG1937	Protein conserved in bacteria
IM697_02800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IM697_02820	COG0494	nUDIX hydrolase
IM697_02820	COG0406	alpha-ribazole phosphatase activity
IM697_02830	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IM697_02845	COG3842	ATPase activity
IM697_02850	COG1725	Transcriptional regulator
IM697_02855	COG0456	acetyltransferase
IM697_02860	COG0737	Belongs to the 5'-nucleotidase family
IM697_02890	COG0745	RESPONSE REGULATOR receiver
IM697_02900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM697_02910	COG1609	Transcriptional regulator
IM697_02915	COG0745	RESPONSE REGULATOR receiver
IM697_02945	COG2897	thiosulfate sulfurtransferase activity
IM697_02980	COG3485	protocatechuate 3,4-dioxygenase
IM697_02990	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IM697_02995	COG1490	D-aminoacyl-tRNA deacylase activity
IM697_03005	COG4552	Acetyltransferase involved in intracellular survival and related
IM697_03015	COG2188	Transcriptional regulator
IM697_03025	COG2188	Transcriptional regulator
IM697_03065	COG3973	AAA domain
IM697_03080	COG1733	regulation of RNA biosynthetic process
IM697_03100	COG3415	Transposase
IM697_03100	COG2801	Transposase and inactivated derivatives
IM697_03115	COG2267	carboxylic ester hydrolase activity
IM697_03175	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IM697_03180	COG0438	transferase activity, transferring glycosyl groups
IM697_03210	COG0588	phosphoglycerate mutase activity
IM697_03230	COG5002	protein histidine kinase activity
IM697_03245	COG1329	Transcriptional regulator
IM697_03250	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IM697_03255	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IM697_03260	COG0215	cysteine-tRNA ligase activity
IM697_03285	COG3842	ATPase activity
IM697_03345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM697_03350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM697_03420	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IM697_03440	COG5001	Diguanylate cyclase
IM697_03440	COG3300	MHYT domain
IM697_03460	COG1105	Belongs to the carbohydrate kinase PfkB family
IM697_03510	COG1105	Belongs to the carbohydrate kinase PfkB family
IM697_03540	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IM697_03545	COG0463	Glycosyl transferase, family 2
IM697_03560	COG1278	Cold shock
IM697_03565	COG0459	protein refolding
IM697_03585	COG0667	Aldo Keto reductase
IM697_03590	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IM697_03595	COG1737	Transcriptional regulator
IM697_03640	COG3973	AAA domain
IM697_03650	COG1061	Type III restriction enzyme res subunit
IM697_03685	COG1278	Cold shock
IM697_03690	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
IM697_03695	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IM697_03705	COG2814	Major facilitator Superfamily
IM697_03715	COG0789	Transcriptional regulator
IM697_03775	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IM697_03785	COG2252	PERMEase
IM697_03825	COG0277	FAD linked oxidase domain protein
IM697_03830	COG2226	methyltransferase
IM697_03885	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IM697_03905	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IM697_03915	COG1609	Transcriptional regulator
IM697_03925	COG1175	transmembrane transport
IM697_03930	COG0395	ABC-type sugar transport system, permease component
IM697_03935	COG0277	FAD linked oxidase domain protein
IM697_03935	COG0247	lactate metabolic process
IM697_03940	COG4977	sequence-specific DNA binding
IM697_03950	COG0596	Alpha beta hydrolase
IM697_03950	COG2945	thiolester hydrolase activity
IM697_03975	COG5006	permease, DMT superfamily
IM697_03990	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IM697_04005	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_04010	COG1024	Enoyl-CoA hydratase
IM697_04020	COG0259	pyridoxamine-phosphate oxidase activity
IM697_04030	COG2815	serine threonine protein kinase
IM697_04030	COG0515	serine threonine protein kinase
IM697_04055	COG4821	SIS domain
IM697_04065	COG0596	Alpha beta hydrolase
IM697_04065	COG2945	thiolester hydrolase activity
IM697_04115	COG1595	DNA-templated transcription, initiation
IM697_04130	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_04135	COG1960	acyl-CoA dehydrogenase activity
IM697_04140	COG1960	acyl-CoA dehydrogenase activity
IM697_04155	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_04160	COG1960	acyl-CoA dehydrogenase activity
IM697_04170	COG2267	carboxylic ester hydrolase activity
IM697_04335	COG1024	Enoyl-CoA hydratase
IM697_04345	COG1231	oxidoreductase activity
IM697_04350	COG2072	flavoprotein involved in K transport
IM697_04380	COG0259	pyridoxamine-phosphate oxidase activity
IM697_04395	COG1960	acyl-CoA dehydrogenase activity
IM697_04405	COG1280	lysine exporter protein (LysE YggA)
IM697_04410	COG1522	sequence-specific DNA binding
IM697_04415	COG1309	transcriptional regulator
IM697_04425	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IM697_04425	COG0515	serine threonine protein kinase
IM697_04460	COG3903	Transcriptional regulator
IM697_04460	COG3629	intracellular signal transduction
IM697_04470	COG1215	transferase activity, transferring glycosyl groups
IM697_04480	COG0438	transferase activity, transferring glycosyl groups
IM697_04485	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IM697_04485	COG0463	Glycosyl transferase, family 2
IM697_04495	COG2197	response regulator
IM697_04550	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
IM697_04575	COG1595	DNA-templated transcription, initiation
IM697_04650	COG1686	Belongs to the peptidase S11 family
IM697_04665	COG0386	Belongs to the glutathione peroxidase family
IM697_04700	COG0202	RNA polymerase activity
IM697_04740	COG1116	anion transmembrane transporter activity
IM697_04745	COG1131	(ABC) transporter
IM697_04755	COG2197	response regulator
IM697_04760	COG4585	Histidine kinase
IM697_04835	COG2018	Roadblock/LC7 domain
IM697_04850	COG1414	Transcriptional regulator
IM697_04870	COG1846	Transcriptional regulator
IM697_04875	COG3384	dioxygenase
IM697_04880	COG1247	-acetyltransferase
IM697_04900	COG0477	Major facilitator Superfamily
IM697_04905	COG1349	DNA-binding transcription factor activity
IM697_04915	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM697_04915	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM697_04915	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM697_04930	COG1376	ErfK ybiS ycfS ynhG family protein
IM697_04935	COG3191	aminopeptidase activity
IM697_04950	COG1970	mechanosensitive ion channel activity
IM697_04960	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IM697_04970	COG0477	Major facilitator Superfamily
IM697_04985	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IM697_04990	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IM697_05000	COG0315	cyclic pyranopterin monophosphate synthase activity
IM697_05005	COG0521	Mo-molybdopterin cofactor biosynthetic process
IM697_05005	COG0315	cyclic pyranopterin monophosphate synthase activity
IM697_05010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM697_05030	COG0454	-acetyltransferase
IM697_05035	COG0708	Exodeoxyribonuclease III
IM697_05045	COG2072	flavoprotein involved in K transport
IM697_05050	COG2267	carboxylic ester hydrolase activity
IM697_05055	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_05065	COG4946	Tricorn protease homolog
IM697_05065	COG0793	Belongs to the peptidase S41A family
IM697_05075	COG2409	Drug exporters of the RND superfamily
IM697_05080	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IM697_05115	COG0442	prolyl-tRNA aminoacylation
IM697_05120	COG1764	response to oxidative stress
IM697_05125	COG1846	Transcriptional regulator
IM697_05130	COG1122	ATPase activity
IM697_05140	COG0310	cobalt ion transport
IM697_05180	COG0084	hydrolase, TatD family'
IM697_05185	COG3583	domain protein
IM697_05185	COG3584	3D domain protein
IM697_05190	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IM697_05195	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IM697_05205	COG0488	(ABC) transporter
IM697_05245	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IM697_05260	COG2197	response regulator
IM697_05270	COG4106	trans-aconitate 2-methyltransferase activity
IM697_05285	COG1309	transcriptional regulator
IM697_05295	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IM697_05300	COG2826	transposase and inactivated derivatives, IS30 family
IM697_05315	COG0193	aminoacyl-tRNA hydrolase activity
IM697_05320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IM697_05325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IM697_05330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IM697_05345	COG4585	Histidine kinase
IM697_05375	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM697_05395	COG0477	Major facilitator Superfamily
IM697_05400	COG1136	(ABC) transporter
IM697_05405	COG0577	efflux transmembrane transporter activity
IM697_05485	COG1652	LysM domain
IM697_05490	COG0148	phosphopyruvate hydratase activity
IM697_05510	COG1252	NADH dehydrogenase
IM697_05515	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IM697_05520	COG0577	efflux transmembrane transporter activity
IM697_05520	COG1136	(ABC) transporter
IM697_05525	COG1136	(ABC) transporter
IM697_05560	COG0183	Belongs to the thiolase family
IM697_05570	COG2755	lipolytic protein G-D-S-L family
IM697_05585	COG1174	glycine betaine transport
IM697_05590	COG1174	glycine betaine transport
IM697_05640	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IM697_05645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM697_05655	COG1228	amidohydrolase
IM697_05675	COG1191	sigma factor activity
IM697_05680	COG1366	Belongs to the anti-sigma-factor antagonist family
IM697_05710	COG3104	oligopeptide transport
IM697_05715	COG0745	RESPONSE REGULATOR receiver
IM697_05720	COG2205	protein histidine kinase activity
IM697_05760	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IM697_05790	COG1316	TRANSCRIPTIONal
IM697_05805	COG1316	TRANSCRIPTIONal
IM697_05810	COG0463	Glycosyl transferase, family 2
IM697_05815	COG1316	TRANSCRIPTIONal
IM697_05820	COG1316	TRANSCRIPTIONal
IM697_05825	COG1316	TRANSCRIPTIONal
IM697_05850	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
IM697_05850	COG0778	Nitroreductase
IM697_05855	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IM697_05890	COG1620	l-lactate permease
IM697_05895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IM697_05900	COG2835	tetraacyldisaccharide 4'-kinase activity
IM697_05910	COG1482	cell wall glycoprotein biosynthetic process
IM697_05920	COG0681	Belongs to the peptidase S26 family
IM697_05925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM697_05925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM697_05925	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM697_05930	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IM697_05970	COG0714	Associated with various cellular activities
IM697_05990	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IM697_05995	COG0745	RESPONSE REGULATOR receiver
IM697_06000	COG5002	protein histidine kinase activity
IM697_06005	COG0823	Involved in the tonB-independent uptake of proteins
IM697_06015	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IM697_06020	COG2197	response regulator
IM697_06025	COG3214	Protein conserved in bacteria
IM697_06035	COG0653	protein targeting
IM697_06060	COG2902	Dehydrogenase
IM697_06065	COG1134	teichoic acid transport
IM697_06090	COG1846	Transcriptional regulator
IM697_06095	COG1764	response to oxidative stress
IM697_06100	COG0463	Glycosyl transferase, family 2
IM697_06100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IM697_06105	COG0395	ABC-type sugar transport system, permease component
IM697_06110	COG1175	transmembrane transport
IM697_06125	COG0515	serine threonine protein kinase
IM697_06130	COG0515	serine threonine protein kinase
IM697_06135	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IM697_06150	COG2884	Cell division ATP-binding protein ftsE
IM697_06160	COG0793	Belongs to the peptidase S41A family
IM697_06165	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IM697_06190	COG2027	D-alanyl-D-alanine carboxypeptidase
IM697_06200	COG1501	Belongs to the glycosyl hydrolase 31 family
IM697_06205	COG2124	cytochrome p450
IM697_06220	COG0583	DNA-binding transcription factor activity
IM697_06270	COG2223	nitrite transmembrane transporter activity
IM697_06295	COG3973	AAA domain
IM697_06305	COG0776	regulation of translation
IM697_06310	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IM697_06315	COG1678	Uncharacterized ACR, COG1678
IM697_06335	COG0395	ABC-type sugar transport system, permease component
IM697_06340	COG3525	Glycosyl hydrolase, family 20, catalytic domain
IM697_06385	COG3654	unkown
IM697_06405	COG4948	Mandelate Racemase Muconate Lactonizing
IM697_06430	COG1174	glycine betaine transport
IM697_06440	COG1174	glycine betaine transport
IM697_06450	COG3185	4-Hydroxyphenylpyruvate dioxygenase
IM697_06460	COG0277	FAD linked oxidase domain protein
IM697_06495	COG1335	isochorismatase
IM697_06510	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IM697_06520	COG1115	amino acid carrier protein
IM697_06520	COG1115	amino acid carrier protein
IM697_06525	COG1113	amino acid transport
IM697_06555	COG1263	PTS System
IM697_06560	COG1263	PTS System
IM697_06565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM697_06570	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IM697_06580	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IM697_06620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM697_06635	COG1131	(ABC) transporter
IM697_06650	COG2733	membrane
IM697_06665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_06760	COG1074	ATP-dependent DNA helicase activity
IM697_06790	COG0270	DNA (cytosine-5-)-methyltransferase activity
IM697_06805	COG3415	Transposase
IM697_06805	COG2801	Transposase and inactivated derivatives
IM697_06825	COG3764	Sortase (surface protein transpeptidase)
IM697_06835	COG0706	membrane insertase activity
IM697_06845	COG4702	Belongs to the UPF0303 family
IM697_06850	COG0673	inositol 2-dehydrogenase activity
IM697_06920	COG3397	chitin binding
IM697_06925	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_06940	COG1126	abc transporter atp-binding protein
IM697_06945	COG0765	amino acid transport
IM697_06950	COG0765	amino acid transport
IM697_07000	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IM697_07010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IM697_07025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_07075	COG0406	alpha-ribazole phosphatase activity
IM697_07100	COG0745	RESPONSE REGULATOR receiver
IM697_07150	COG0589	response to stress
IM697_07160	COG4977	sequence-specific DNA binding
IM697_07165	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IM697_07175	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IM697_07205	COG3486	L-lysine 6-monooxygenase (NADPH) activity
IM697_07225	COG1960	acyl-CoA dehydrogenase activity
IM697_07240	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IM697_07245	COG1309	transcriptional regulator
IM697_07250	COG1525	nuclease
IM697_07260	COG1946	Acyl-CoA thioesterase
IM697_07280	COG0028	Belongs to the TPP enzyme family
IM697_07310	COG2356	endonuclease I
IM697_07345	COG1472	Belongs to the glycosyl hydrolase 3 family
IM697_07370	COG1846	Transcriptional regulator
IM697_07370	COG0456	acetyltransferase
IM697_07390	COG0673	inositol 2-dehydrogenase activity
IM697_07405	COG1609	Transcriptional regulator
IM697_07410	COG1129	ABC transporter
IM697_07420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM697_07425	COG1869	D-ribose catabolic process
IM697_07435	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IM697_07460	COG2409	Drug exporters of the RND superfamily
IM697_07470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM697_07480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM697_07490	COG3962	Belongs to the TPP enzyme family
IM697_07550	COG0728	peptidoglycan biosynthetic process
IM697_07560	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IM697_07565	COG0438	transferase activity, transferring glycosyl groups
IM697_07615	COG2304	oxidoreductase activity
IM697_07625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IM697_07665	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IM697_07685	COG0629	single-stranded DNA binding
IM697_07715	COG2346	COG2346, Truncated hemoglobins
IM697_07765	COG1486	melibiose metabolic process
IM697_07770	COG0395	ABC-type sugar transport system, permease component
IM697_07775	COG1175	transmembrane transport
IM697_07785	COG1940	carbohydrate kinase activity
IM697_07795	COG0668	transmembrane transport
IM697_07810	COG1136	(ABC) transporter
IM697_07840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM697_07920	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IM697_07930	COG0584	glycerophosphoryl diester phosphodiesterase
IM697_07950	COG1349	DNA-binding transcription factor activity
IM697_07955	COG3842	ATPase activity
IM697_07960	COG0395	ABC-type sugar transport system, permease component
IM697_07965	COG1175	transmembrane transport
IM697_07970	COG1653	transport
IM697_07980	COG0588	phosphoglycerate mutase activity
IM697_07990	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IM697_07995	COG1113	amino acid transport
IM697_08000	COG1268	BioY protein
IM697_08010	COG0515	serine threonine protein kinase
IM697_08015	COG1113	amino acid transport
IM697_08020	COG0698	ribose 5-phosphate isomerase
IM697_08035	COG4552	Acetyltransferase involved in intracellular survival and related
IM697_08050	COG3594	Acyltransferase
IM697_08075	COG0544	peptidyl-prolyl cis-trans isomerase activity
IM697_08080	COG0740	serine-type endopeptidase activity
IM697_08085	COG0740	serine-type endopeptidase activity
IM697_08090	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IM697_08100	COG0525	valine-tRNA ligase activity
IM697_08105	COG0285	dihydrofolate synthase activity
IM697_08115	COG0105	UTP biosynthetic process
IM697_08120	COG1077	Cell shape determining protein MreB Mrl
IM697_08135	COG0768	penicillin binding
IM697_08140	COG0772	Belongs to the SEDS family
IM697_08170	COG3387	PFAM Glycoside hydrolase 15-related
IM697_08175	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IM697_08180	COG3265	gluconokinase activity
IM697_08190	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IM697_08210	COG1530	ribonuclease E activity
IM697_08215	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IM697_08220	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IM697_08225	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IM697_08230	COG3540	Alkaline phosphatase
IM697_08250	COG1215	transferase activity, transferring glycosyl groups
IM697_08260	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IM697_08270	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IM697_08285	COG0501	Belongs to the peptidase M48B family
IM697_08300	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IM697_08310	COG0799	negative regulation of ribosome biogenesis
IM697_08315	COG0588	phosphoglycerate mutase activity
IM697_08335	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IM697_08345	COG0495	leucyl-tRNA aminoacylation
IM697_08355	COG1307	EDD domain protein, DegV family
IM697_08360	COG1596	polysaccharide export
IM697_08360	COG1555	photosystem II stabilization
IM697_08375	COG2353	YceI-like domain
IM697_08395	COG0268	Binds directly to 16S ribosomal RNA
IM697_08400	COG0481	GTPase activity
IM697_08445	COG1420	regulation of RNA biosynthetic process
IM697_08450	COG0484	heat shock protein binding
IM697_08475	COG4946	Tricorn protease homolog
IM697_08475	COG0793	Belongs to the peptidase S41A family
IM697_08480	COG0537	adenosine 5'-monophosphoramidase activity
IM697_08485	COG1234	tRNA 3'-trailer cleavage
IM697_08490	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IM697_08505	COG4948	Mandelate Racemase Muconate Lactonizing
IM697_08510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM697_08545	COG2315	Protein conserved in bacteria
IM697_08555	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IM697_08565	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IM697_08595	COG2801	Transposase and inactivated derivatives
IM697_08595	COG3415	Transposase
IM697_08605	COG2723	6-phospho-beta-galactosidase activity
IM697_08620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IM697_08630	COG2409	Drug exporters of the RND superfamily
IM697_08635	COG4585	Histidine kinase
IM697_08640	COG2197	response regulator
IM697_08665	COG4608	Belongs to the ABC transporter superfamily
IM697_08680	COG0747	negative chemotaxis
IM697_08685	COG2186	Transcriptional regulator
IM697_08700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IM697_08715	COG1595	DNA-templated transcription, initiation
IM697_08740	COG0456	acetyltransferase
IM697_08805	COG1381	Involved in DNA repair and RecF pathway recombination
IM697_08810	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IM697_08825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IM697_08830	COG1120	ATPase activity
IM697_08835	COG0803	Belongs to the bacterial solute-binding protein 9 family
IM697_08835	COG3443	Belongs to the bacterial solute-binding protein 9 family
IM697_08840	COG0423	glycine-tRNA ligase activity
IM697_08850	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IM697_08850	COG0116	Belongs to the methyltransferase superfamily
IM697_08860	COG0667	Aldo Keto reductase
IM697_08875	COG0477	Major facilitator Superfamily
IM697_08905	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IM697_08910	COG1846	Transcriptional regulator
IM697_08910	COG1940	carbohydrate kinase activity
IM697_08915	COG0574	Belongs to the PEP-utilizing enzyme family
IM697_08915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IM697_08930	COG1051	belongs to the nudix hydrolase family
IM697_08940	COG0659	secondary active sulfate transmembrane transporter activity
IM697_08950	COG0745	RESPONSE REGULATOR receiver
IM697_08955	COG0642	Histidine kinase
IM697_08975	COG4221	oxidoreductase activity
IM697_08980	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_08985	COG1309	transcriptional regulator
IM697_08995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IM697_08995	COG2146	nitrite reductase [NAD(P)H] activity
IM697_09000	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IM697_09030	COG1733	regulation of RNA biosynthetic process
IM697_09060	COG0243	molybdopterin cofactor binding
IM697_09075	COG2949	membrane
IM697_09090	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IM697_09100	COG0358	DNA primase activity
IM697_09105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IM697_09120	COG1070	Carbohydrate kinase
IM697_09175	COG0589	response to stress
IM697_09195	COG3290	protein histidine kinase activity
IM697_09200	COG4565	transcriptional regulatory protein
IM697_09210	COG1077	Cell shape determining protein MreB Mrl
IM697_09215	COG0515	serine threonine protein kinase
IM697_09215	COG2815	serine threonine protein kinase
IM697_09230	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IM697_09230	COG0825	malonyl-CoA metabolic process
IM697_09235	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_09245	COG2186	Transcriptional regulator
IM697_09250	COG2801	Transposase and inactivated derivatives
IM697_09250	COG3415	Transposase
IM697_09290	COG2835	tetraacyldisaccharide 4'-kinase activity
IM697_09310	COG4981	capsule polysaccharide biosynthetic process
IM697_09360	COG1414	Transcriptional regulator
IM697_09365	COG3386	PFAM SMP-30 Gluconolaconase
IM697_09415	COG0395	ABC-type sugar transport system, permease component
IM697_09455	COG0477	Major facilitator Superfamily
IM697_09460	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IM697_09470	COG3507	Belongs to the glycosyl hydrolase 43 family
IM697_09475	COG3940	Belongs to the glycosyl hydrolase 43 family
IM697_09490	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IM697_09500	COG4214	carbohydrate transport
IM697_09505	COG1129	ABC transporter
IM697_09525	COG4948	Mandelate Racemase Muconate Lactonizing
IM697_09535	COG1609	Transcriptional regulator
IM697_09540	COG1879	ABC-type sugar transport system periplasmic component
IM697_09550	COG1172	Belongs to the binding-protein-dependent transport system permease family
IM697_09555	COG1172	Belongs to the binding-protein-dependent transport system permease family
IM697_09565	COG2130	NADP-dependent
IM697_09570	COG1764	response to oxidative stress
IM697_09620	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM697_09625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM697_09630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IM697_09660	COG0789	Transcriptional regulator
IM697_09665	COG0667	Aldo Keto reductase
IM697_09680	COG1309	transcriptional regulator
IM697_09685	COG0477	Major facilitator Superfamily
IM697_09690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IM697_09695	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IM697_09740	COG1358	cellular component organization or biogenesis
IM697_09755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM697_09835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM697_09845	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IM697_09860	COG2259	Doxx family
IM697_09915	COG4122	O-methyltransferase activity
IM697_09950	COG0183	Belongs to the thiolase family
IM697_09955	COG2124	cytochrome p450
IM697_09975	COG3845	ABC transporter
IM697_09990	COG1657	PFAM Prenyltransferase squalene oxidase
IM697_09995	COG0251	oxidation-reduction process
IM697_10030	COG1309	transcriptional regulator
IM697_10035	COG0438	transferase activity, transferring glycosyl groups
IM697_10055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_10065	COG0860	N-Acetylmuramoyl-L-alanine amidase
IM697_10130	COG2197	response regulator
IM697_10145	COG2030	dehydratase
IM697_10155	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_10170	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IM697_10185	COG0800	Aldolase
IM697_10190	COG3022	response to hydroperoxide
IM697_10205	COG0789	Transcriptional regulator
IM697_10285	COG1201	RNA secondary structure unwinding
IM697_10320	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IM697_10350	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IM697_10375	COG0745	RESPONSE REGULATOR receiver
IM697_10385	COG2259	Doxx family
IM697_10395	COG0667	Aldo Keto reductase
IM697_10400	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_10405	COG3540	Alkaline phosphatase
IM697_10415	COG2814	Major facilitator Superfamily
IM697_10420	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM697_10460	COG1120	ATPase activity
IM697_10465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_10515	COG1994	Peptidase M50
IM697_10535	COG2814	Major facilitator Superfamily
IM697_10550	COG0477	Major facilitator Superfamily
IM697_10555	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IM697_10600	COG0174	glutamine synthetase
IM697_10625	COG0174	glutamine synthetase
IM697_10630	COG1017	nitric oxide dioxygenase activity
IM697_10630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IM697_10635	COG1959	2 iron, 2 sulfur cluster binding
IM697_10655	COG0640	Transcriptional regulator
IM697_10660	COG0346	lactoylglutathione lyase activity
IM697_10685	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IM697_10695	COG1609	Transcriptional regulator
IM697_10700	COG1653	transport
IM697_10705	COG1175	transmembrane transport
IM697_10710	COG3833	ABC-type maltose transport systems, permease component
IM697_10715	COG0366	Alpha amylase catalytic
IM697_10750	COG1309	transcriptional regulator
IM697_10785	COG2197	response regulator
IM697_10800	COG0745	RESPONSE REGULATOR receiver
IM697_10840	COG0501	Belongs to the peptidase M48B family
IM697_10850	COG0174	glutamine synthetase
IM697_10870	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IM697_10875	COG0321	lipoyl(octanoyl) transferase activity
IM697_10890	COG1090	epimerase
IM697_10930	COG0733	neurotransmitter:sodium symporter activity
IM697_10940	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IM697_10950	COG0508	dehydrogenase complex catalyzes the overall conversion of
IM697_10955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IM697_10960	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IM697_10985	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IM697_10995	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IM697_11015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM697_11020	COG2226	methyltransferase
IM697_11045	COG2197	response regulator
IM697_11050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM697_11055	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IM697_11075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM697_11085	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IM697_11090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IM697_11100	COG1376	ErfK ybiS ycfS ynhG family protein
IM697_11110	COG1845	cytochrome c oxidase, subunit III
IM697_11115	COG2010	Cytochrome c
IM697_11120	COG0723	plastoquinol--plastocyanin reductase activity
IM697_11125	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IM697_11130	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IM697_11135	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IM697_11140	COG1929	Belongs to the glycerate kinase type-1 family
IM697_11150	COG0745	RESPONSE REGULATOR receiver
IM697_11155	COG2205	protein histidine kinase activity
IM697_11185	COG0791	NLP P60 protein
IM697_11230	COG0003	Pfam Anion-transporting ATPase
IM697_11240	COG1940	carbohydrate kinase activity
IM697_11275	COG0205	6-phosphofructokinase activity
IM697_11290	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IM697_11295	COG0243	molybdopterin cofactor binding
IM697_11300	COG2193	ferroxidase activity
IM697_11305	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IM697_11315	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IM697_11320	COG0515	serine threonine protein kinase
IM697_11320	COG2815	serine threonine protein kinase
IM697_11325	COG2022	thiamine diphosphate biosynthetic process
IM697_11335	COG2022	thiamine diphosphate biosynthetic process
IM697_11335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_11355	COG0352	thiamine-phosphate diphosphorylase activity
IM697_11380	COG1309	transcriptional regulator
IM697_11390	COG1131	(ABC) transporter
IM697_11400	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IM697_11420	COG0714	Associated with various cellular activities
IM697_11430	COG0275	rRNA processing
IM697_11445	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IM697_11455	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IM697_11460	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IM697_11470	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IM697_11475	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IM697_11480	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IM697_11485	COG1496	oxidoreductase activity
IM697_11495	COG1799	cell septum assembly
IM697_11505	COG3599	regulation of cell shape
IM697_11510	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IM697_11520	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IM697_11580	COG0587	DNA-directed DNA polymerase activity
IM697_11590	COG1432	Conserved Protein
IM697_11610	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IM697_11630	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IM697_11635	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IM697_11640	COG0131	Imidazoleglycerol-phosphate dehydratase
IM697_11650	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IM697_11655	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IM697_11660	COG0251	oxidation-reduction process
IM697_11665	COG0107	imidazoleglycerol-phosphate synthase activity
IM697_11685	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IM697_11710	COG0134	indole-3-glycerol-phosphate synthase activity
IM697_11715	COG0133	tryptophan synthase activity
IM697_11720	COG0159	tryptophan synthase activity
IM697_11730	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IM697_11740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IM697_11745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM697_11775	COG0069	glutamate synthase activity
IM697_11775	COG0067	glutamate synthase
IM697_11775	COG0070	glutamate synthase
IM697_11795	COG2304	oxidoreductase activity
IM697_11800	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IM697_11810	COG1960	acyl-CoA dehydrogenase activity
IM697_11815	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_11820	COG1309	transcriptional regulator
IM697_11825	COG0183	Belongs to the thiolase family
IM697_11845	COG1024	Enoyl-CoA hydratase
IM697_11855	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_11865	COG5640	endopeptidase activity
IM697_11880	COG0287	Prephenate dehydrogenase
IM697_11880	COG1605	Chorismate mutase
IM697_11885	COG0745	RESPONSE REGULATOR receiver
IM697_11915	COG0737	Belongs to the 5'-nucleotidase family
IM697_11950	COG0411	ABC transporter
IM697_11970	COG2050	protein possibly involved in aromatic compounds catabolism
IM697_12005	COG1643	Atp-dependent helicase
IM697_12015	COG0539	negative regulation of cytoplasmic translation
IM697_12025	COG0237	dephospho-CoA kinase activity
IM697_12060	COG2267	carboxylic ester hydrolase activity
IM697_12065	COG1802	Transcriptional regulator
IM697_12070	COG1953	Uracil, thiamine, allantoin
IM697_12085	COG0251	oxidation-reduction process
IM697_12105	COG0402	S-adenosylhomocysteine deaminase activity
IM697_12160	COG0574	Belongs to the PEP-utilizing enzyme family
IM697_12160	COG3848	Pyruvate phosphate dikinase
IM697_12165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM697_12170	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IM697_12205	COG0598	Magnesium transport protein CorA
IM697_12210	COG2226	methyltransferase
IM697_12215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM697_12220	COG2313	pseudouridylate synthase activity
IM697_12230	COG1063	alcohol dehydrogenase
IM697_12240	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IM697_12245	COG0584	glycerophosphoryl diester phosphodiesterase
IM697_12255	COG0556	nucleotide-excision repair
IM697_12280	COG0387	Pfam Sodium calcium exchanger
IM697_12285	COG0477	Major facilitator Superfamily
IM697_12295	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IM697_12300	COG1126	abc transporter atp-binding protein
IM697_12305	COG0765	amino acid transport
IM697_12310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM697_12325	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IM697_12335	COG1609	Transcriptional regulator
IM697_12345	COG0322	excinuclease ABC activity
IM697_12350	COG1660	Displays ATPase and GTPase activities
IM697_12355	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IM697_12360	COG1481	regulation of sporulation
IM697_12370	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IM697_12375	COG0126	phosphoglycerate kinase activity
IM697_12380	COG0149	triose-phosphate isomerase activity
IM697_12385	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IM697_12400	COG0166	Belongs to the GPI family
IM697_12410	COG1136	(ABC) transporter
IM697_12415	COG1695	Transcriptional regulator
IM697_12420	COG1653	transport
IM697_12425	COG0366	Alpha amylase catalytic
IM697_12430	COG1653	transport
IM697_12435	COG1175	transmembrane transport
IM697_12440	COG0395	ABC-type sugar transport system, permease component
IM697_12445	COG0363	glucosamine-6-phosphate deaminase activity
IM697_12460	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IM697_12470	COG0109	protoheme IX farnesyltransferase activity
IM697_12490	COG1612	heme a metabolic process
IM697_12520	COG0719	Fe-S assembly protein
IM697_12530	COG0396	ATPase activity
IM697_12535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IM697_12540	COG0822	iron-sulfur transferase activity
IM697_12545	COG2151	metal-sulfur cluster biosynthetic enzyme
IM697_12565	COG1733	regulation of RNA biosynthetic process
IM697_12575	COG3226	Transcriptional regulator
IM697_12580	COG2171	N-acyltransferase activity
IM697_12590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM697_12645	COG1802	Transcriptional regulator
IM697_12655	COG1609	Transcriptional regulator
IM697_12665	COG1063	alcohol dehydrogenase
IM697_12690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IM697_12695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM697_12725	COG1802	Transcriptional regulator
IM697_12730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM697_12740	COG1175	transmembrane transport
IM697_12745	COG0395	ABC-type sugar transport system, permease component
IM697_12750	COG3866	Pectate lyase
IM697_12765	COG3507	Belongs to the glycosyl hydrolase 43 family
IM697_12770	COG4677	pectinesterase activity
IM697_12780	COG2755	lipolytic protein G-D-S-L family
IM697_12785	COG3866	Pectate lyase
IM697_12790	COG4677	pectinesterase activity
IM697_12795	COG4677	pectinesterase activity
IM697_12810	COG4733	cellulase activity
IM697_12825	COG1595	DNA-templated transcription, initiation
IM697_12830	COG2252	PERMEase
IM697_12855	COG0768	penicillin binding
IM697_12860	COG2197	response regulator
IM697_12865	COG4585	Histidine kinase
IM697_12880	COG1414	Transcriptional regulator
IM697_12905	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IM697_12910	COG1595	DNA-templated transcription, initiation
IM697_12920	COG5285	phytanoyl-CoA dioxygenase
IM697_12925	COG1917	Cupin 2, conserved barrel domain protein
IM697_12930	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IM697_12935	COG0456	acetyltransferase
IM697_12940	COG2318	DinB family
IM697_12945	COG1104	cysteine desulfurase activity
IM697_12950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM697_12955	COG0765	amino acid transport
IM697_12960	COG1126	abc transporter atp-binding protein
IM697_13050	COG1492	cobalamin metabolic process
IM697_13055	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IM697_13075	COG0235	Class ii aldolase
IM697_13095	COG0488	(ABC) transporter
IM697_13145	COG3387	PFAM Glycoside hydrolase 15-related
IM697_13170	COG1966	Carbon starvation protein
IM697_13205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IM697_13220	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM697_13225	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IM697_13245	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IM697_13255	COG0312	modulator of DNA gyrase
IM697_13275	COG2186	Transcriptional regulator
IM697_13280	COG2807	transmembrane transport
IM697_13295	COG3830	Belongs to the UPF0237 family
IM697_13295	COG0560	Phosphoserine phosphatase
IM697_13305	COG0842	Transport permease protein
IM697_13305	COG1131	(ABC) transporter
IM697_13305	COG1716	ATPase activity
IM697_13325	COG4221	oxidoreductase activity
IM697_13340	COG2197	response regulator
IM697_13355	COG1119	ATPase activity
IM697_13375	COG1881	PFAM PEBP family protein
IM697_13385	COG2094	Belongs to the DNA glycosylase MPG family
IM697_13415	COG0647	UMP catabolic process
IM697_13420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_13425	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_13430	COG1120	ATPase activity
IM697_13450	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IM697_13455	COG0497	DNA recombination
IM697_13465	COG0297	glycogen (starch) synthase activity
IM697_13485	COG3387	PFAM Glycoside hydrolase 15-related
IM697_13490	COG0504	CTP synthase activity
IM697_13495	COG0494	nUDIX hydrolase
IM697_13505	COG0686	Belongs to the AlaDH PNT family
IM697_13520	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IM697_13525	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IM697_13530	COG1187	pseudouridine synthase activity
IM697_13545	COG0477	Major facilitator Superfamily
IM697_13550	COG0494	nUDIX hydrolase
IM697_13585	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IM697_13595	COG1160	GTP binding
IM697_13610	COG1652	LysM domain
IM697_13615	COG3583	domain protein
IM697_13625	COG0411	ABC transporter
IM697_13665	COG0671	phosphoesterase, PA-phosphatase related
IM697_13670	COG0477	Major facilitator Superfamily
IM697_13675	COG1960	acyl-CoA dehydrogenase activity
IM697_13680	COG1799	cell septum assembly
IM697_13695	COG0330	HflC and HflK could
IM697_13710	COG0587	DNA-directed DNA polymerase activity
IM697_13715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IM697_13750	COG2226	methyltransferase
IM697_13765	COG1725	Transcriptional regulator
IM697_13790	COG1649	PFAM Uncharacterised BCR, COG1649
IM697_13790	COG0726	polysaccharide deacetylase
IM697_13820	COG2755	lipolytic protein G-D-S-L family
IM697_13825	COG0515	serine threonine protein kinase
IM697_13825	COG2815	serine threonine protein kinase
IM697_13845	COG1595	DNA-templated transcription, initiation
IM697_13880	COG2188	Transcriptional regulator
IM697_13885	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IM697_13895	COG1309	transcriptional regulator
IM697_13900	COG0243	molybdopterin cofactor binding
IM697_13905	COG2851	Citrate transporter
IM697_13940	COG0477	Major facilitator Superfamily
IM697_13945	COG0697	spore germination
IM697_13950	COG0640	Transcriptional regulator
IM697_13960	COG1960	acyl-CoA dehydrogenase activity
IM697_13980	COG0789	Transcriptional regulator
IM697_14010	COG3876	Protein conserved in bacteria
IM697_14015	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_14020	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_14030	COG2197	response regulator
IM697_14035	COG4585	Histidine kinase
IM697_14070	COG2149	membrane
IM697_14075	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IM697_14115	COG1063	alcohol dehydrogenase
IM697_14120	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_14130	COG3265	gluconokinase activity
IM697_14135	COG2186	Transcriptional regulator
IM697_14140	COG3012	SEC-C Motif Domain Protein
IM697_14145	COG0308	aminopeptidase N
IM697_14195	COG0667	Aldo Keto reductase
IM697_14200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_14210	COG0598	Magnesium transport protein CorA
IM697_14215	COG0588	phosphoglycerate mutase activity
IM697_14230	COG0215	cysteine-tRNA ligase activity
IM697_14240	COG4935	Belongs to the peptidase S8 family
IM697_14240	COG1404	Belongs to the peptidase S8 family
IM697_14255	COG2186	Transcriptional regulator
IM697_14260	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IM697_14265	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IM697_14270	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IM697_14275	COG1414	Transcriptional regulator
IM697_14280	COG1410	methionine synthase
IM697_14280	COG0646	methionine synthase
IM697_14290	COG0747	negative chemotaxis
IM697_14295	COG0747	negative chemotaxis
IM697_14300	COG2197	response regulator
IM697_14310	COG0517	IMP dehydrogenase activity
IM697_14310	COG1994	Peptidase M50
IM697_14330	COG1222	aaa ATPase
IM697_14335	COG4122	O-methyltransferase activity
IM697_14350	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IM697_14355	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IM697_14360	COG1609	Transcriptional regulator
IM697_14370	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IM697_14405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IM697_14410	COG0805	protein transport
IM697_14420	COG3973	AAA domain
IM697_14455	COG0564	pseudouridine synthase activity
IM697_14465	COG2124	cytochrome p450
IM697_14475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IM697_14480	COG4175	Glycine betaine
IM697_14480	COG0517	IMP dehydrogenase activity
IM697_14485	COG4176	ABC-type proline glycine betaine transport system permease component
IM697_14495	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IM697_14510	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IM697_14515	COG0531	amino acid
IM697_14525	COG0174	glutamine synthetase
IM697_14530	COG1012	belongs to the aldehyde dehydrogenase family
IM697_14535	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_14575	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IM697_14580	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IM697_14585	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IM697_14590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IM697_14595	COG5002	protein histidine kinase activity
IM697_14600	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IM697_14605	COG0072	phenylalanine-tRNA ligase activity
IM697_14605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM697_14635	COG1649	PFAM Uncharacterised BCR, COG1649
IM697_14645	COG0697	spore germination
IM697_14675	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IM697_14680	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IM697_14685	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IM697_14690	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IM697_14695	COG1438	arginine binding
IM697_14730	COG0165	Argininosuccinate lyase
IM697_14745	COG0477	Major facilitator Superfamily
IM697_14750	COG0714	Associated with various cellular activities
IM697_14760	COG2304	oxidoreductase activity
IM697_14765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM697_14770	COG0745	RESPONSE REGULATOR receiver
IM697_14775	COG2205	protein histidine kinase activity
IM697_14780	COG0204	Acyl-transferase
IM697_14780	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_14815	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IM697_14820	COG2011	ABC-type metal ion transport system permease component
IM697_14825	COG1464	Belongs to the NlpA lipoprotein family
IM697_14840	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IM697_14845	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IM697_14845	COG1648	precorrin-2 dehydrogenase activity
IM697_14855	COG0494	nUDIX hydrolase
IM697_14910	COG0512	Glutamine amidotransferase of anthranilate synthase
IM697_14910	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IM697_14920	COG0456	acetyltransferase
IM697_14965	COG1175	transmembrane transport
IM697_14970	COG0395	ABC-type sugar transport system, permease component
IM697_15000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IM697_15015	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IM697_15020	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IM697_15040	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IM697_15045	COG1560	Kdo2-lipid A biosynthetic process
IM697_15050	COG0438	transferase activity, transferring glycosyl groups
IM697_15060	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IM697_15065	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IM697_15070	COG0217	transcriptional regulatory protein
IM697_15075	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IM697_15080	COG0632	four-way junction helicase activity
IM697_15085	COG2255	four-way junction helicase activity
IM697_15095	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IM697_15100	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IM697_15105	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IM697_15110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IM697_15115	COG1196	nuclear chromosome segregation
IM697_15120	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IM697_15130	COG0124	histidyl-tRNA synthetase
IM697_15145	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IM697_15165	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IM697_15170	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IM697_15175	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IM697_15180	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IM697_15190	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IM697_15195	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IM697_15200	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IM697_15210	COG0006	proline dipeptidase activity
IM697_15215	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IM697_15220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IM697_15230	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IM697_15235	COG0540	Belongs to the ATCase OTCase family
IM697_15240	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IM697_15250	COG0505	Belongs to the CarA family
IM697_15255	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IM697_15260	COG0167	dihydroorotate dehydrogenase activity
IM697_15265	COG0284	orotidine-5'-phosphate decarboxylase activity
IM697_15275	COG0194	GDP metabolic process
IM697_15280	COG1758	RNA polymerase activity
IM697_15290	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IM697_15325	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IM697_15335	COG2409	Drug exporters of the RND superfamily
IM697_15340	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IM697_15345	COG2390	Transcriptional regulator
IM697_15355	COG3903	Transcriptional regulator
IM697_15355	COG3629	intracellular signal transduction
IM697_15375	COG0531	amino acid
IM697_15390	COG2188	Transcriptional regulator
IM697_15400	COG1176	ABC-type spermidine putrescine transport system, permease component I
IM697_15410	COG3842	ATPase activity
IM697_15415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM697_15430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IM697_15470	COG5002	protein histidine kinase activity
IM697_15475	COG0745	RESPONSE REGULATOR receiver
IM697_15505	COG1846	Transcriptional regulator
IM697_15505	COG1940	carbohydrate kinase activity
IM697_15510	COG1090	epimerase
IM697_15525	COG3201	nicotinamide mononucleotide transporter
IM697_15530	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IM697_15530	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IM697_15535	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IM697_15540	COG0140	phosphoribosyl-ATP diphosphatase activity
IM697_15545	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IM697_15605	COG1960	acyl-CoA dehydrogenase activity
IM697_15635	COG1216	Glycosyl transferase, family 2
IM697_15640	COG3030	protein affecting phage T7 exclusion by the F plasmid
IM697_15650	COG2270	Major facilitator Superfamily
IM697_15660	COG2364	Membrane
IM697_15665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM697_15695	COG0438	transferase activity, transferring glycosyl groups
IM697_15705	COG1984	allophanate hydrolase subunit 2
IM697_15710	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IM697_15715	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IM697_15720	COG4336	lyase activity
IM697_15725	COG2814	Major facilitator Superfamily
IM697_15780	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IM697_15785	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IM697_15795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IM697_15815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IM697_15825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IM697_15855	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IM697_15875	COG1716	ATPase activity
IM697_15895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IM697_15905	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IM697_15905	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IM697_15940	COG1175	transmembrane transport
IM697_15945	COG0395	ABC-type sugar transport system, permease component
IM697_15970	COG4941	Belongs to the sigma-70 factor family
IM697_15975	COG3795	YCII-related domain
IM697_15995	COG4106	trans-aconitate 2-methyltransferase activity
IM697_16050	COG0697	spore germination
IM697_16055	COG0583	DNA-binding transcription factor activity
IM697_16095	COG0747	negative chemotaxis
IM697_16100	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IM697_16115	COG2318	DinB family
IM697_16135	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IM697_16150	COG1968	undecaprenyl-diphosphatase activity
IM697_16170	COG0183	Belongs to the thiolase family
IM697_16205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IM697_16230	COG0110	maltose O-acetyltransferase activity
IM697_16255	COG0640	Transcriptional regulator
IM697_16265	COG1832	CoA-binding protein
IM697_16300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IM697_16315	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IM697_16330	COG1012	belongs to the aldehyde dehydrogenase family
IM697_16335	COG4175	Glycine betaine
IM697_16335	COG0517	IMP dehydrogenase activity
IM697_16340	COG4176	ABC-type proline glycine betaine transport system permease component
IM697_16350	COG1802	Transcriptional regulator
IM697_16355	COG0247	lactate metabolic process
IM697_16355	COG2181	nitrate reductase activity
IM697_16360	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IM697_16365	COG2086	electron transfer activity
IM697_16375	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IM697_16405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_16410	COG4638	Rieske (2fe-2S)
IM697_16415	COG3290	protein histidine kinase activity
IM697_16425	COG0509	glycine decarboxylation via glycine cleavage system
IM697_16430	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IM697_16435	COG1760	l-serine dehydratase
IM697_16440	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IM697_16445	COG0438	transferase activity, transferring glycosyl groups
IM697_16450	COG0215	cysteine-tRNA ligase activity
IM697_16460	COG1739	Uncharacterized protein family UPF0029
IM697_16475	COG0420	3'-5' exonuclease activity
IM697_16480	COG0419	ATPase involved in DNA repair
IM697_16500	COG0745	RESPONSE REGULATOR receiver
IM697_16505	COG2205	protein histidine kinase activity
IM697_16510	COG1522	sequence-specific DNA binding
IM697_16525	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_16540	COG0626	cystathionine gamma-synthase activity
IM697_16565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM697_16610	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
IM697_16610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_16625	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IM697_16630	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IM697_16655	COG0475	glutathione-regulated potassium exporter activity
IM697_16675	COG1595	DNA-templated transcription, initiation
IM697_16680	COG2188	Transcriptional regulator
IM697_16685	COG1940	carbohydrate kinase activity
IM697_16690	COG2197	response regulator
IM697_16695	COG4585	Histidine kinase
IM697_16715	COG3663	DNA glycosylase
IM697_16720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IM697_16745	COG0456	acetyltransferase
IM697_16755	COG1136	(ABC) transporter
IM697_16755	COG0577	efflux transmembrane transporter activity
IM697_16760	COG1136	(ABC) transporter
IM697_16760	COG0577	efflux transmembrane transporter activity
IM697_16775	COG2226	methyltransferase
IM697_16790	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IM697_16795	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IM697_16800	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IM697_16825	COG0583	DNA-binding transcription factor activity
IM697_16830	COG1280	lysine exporter protein (LysE YggA)
IM697_16845	COG0740	serine-type endopeptidase activity
IM697_16860	COG1309	transcriptional regulator
IM697_16865	COG0831	urea catabolic process
IM697_16870	COG0832	Belongs to the urease beta subunit family
IM697_16875	COG0804	urea catabolic process
IM697_16885	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IM697_16890	COG0829	nickel cation binding
IM697_16910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IM697_16915	COG1834	amidinotransferase
IM697_16920	COG1522	sequence-specific DNA binding
IM697_16925	COG3279	Response regulator of the LytR AlgR family
IM697_16935	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM697_16940	COG3275	phosphorelay sensor kinase activity
IM697_16950	COG2815	serine threonine protein kinase
IM697_16950	COG0515	serine threonine protein kinase
IM697_16965	COG0205	6-phosphofructokinase activity
IM697_16970	COG3442	glutamine amidotransferase
IM697_16980	COG0242	peptide deformylase activity
IM697_16990	COG1960	acyl-CoA dehydrogenase activity
IM697_17000	COG1012	belongs to the aldehyde dehydrogenase family
IM697_17010	COG1793	dna ligase
IM697_17015	COG0492	ferredoxin-NADP+ reductase activity
IM697_17030	COG1960	acyl-CoA dehydrogenase activity
IM697_17035	COG1960	acyl-CoA dehydrogenase activity
IM697_17070	COG3903	Transcriptional regulator
IM697_17070	COG3629	intracellular signal transduction
IM697_17095	COG0586	Pfam SNARE associated Golgi protein
IM697_17100	COG4214	carbohydrate transport
IM697_17110	COG4213	ABC transporter substrate-binding protein
IM697_17120	COG4213	ABC transporter substrate-binding protein
IM697_17145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_17165	COG1082	Xylose isomerase domain protein TIM barrel
IM697_17200	COG3693	PFAM glycoside hydrolase, family 10
IM697_17215	COG1012	belongs to the aldehyde dehydrogenase family
IM697_17245	COG1940	carbohydrate kinase activity
IM697_17245	COG1846	Transcriptional regulator
IM697_17275	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IM697_17310	COG0642	Histidine kinase
IM697_17335	COG2018	Roadblock/LC7 domain
IM697_17345	COG1946	Acyl-CoA thioesterase
IM697_17360	COG0254	rRNA binding
IM697_17375	COG1132	(ABC) transporter
IM697_17380	COG1132	(ABC) transporter
IM697_17405	COG1132	(ABC) transporter
IM697_17415	COG2072	flavoprotein involved in K transport
IM697_17420	COG0432	Pfam Uncharacterised protein family UPF0047
IM697_17505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_17510	COG1120	ATPase activity
IM697_17515	COG2814	Major facilitator Superfamily
IM697_17520	COG0367	asparagine synthase
IM697_17540	COG0277	FAD linked oxidase domain protein
IM697_17570	COG1082	Xylose isomerase domain protein TIM barrel
IM697_17575	COG0673	inositol 2-dehydrogenase activity
IM697_17585	COG1609	Transcriptional regulator
IM697_17595	COG0791	NLP P60 protein
IM697_17595	COG0741	lytic transglycosylase activity
IM697_17605	COG4948	Mandelate Racemase Muconate Lactonizing
IM697_17610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM697_17615	COG0395	ABC-type sugar transport system, permease component
IM697_17620	COG1175	transmembrane transport
IM697_17625	COG1653	transport
IM697_17655	COG1222	aaa ATPase
IM697_17730	COG3396	Phenylacetate-CoA oxygenase
IM697_17735	COG3460	Phenylacetate-CoA oxygenase
IM697_17740	COG3396	Phenylacetate-CoA oxygenase
IM697_17745	COG2151	metal-sulfur cluster biosynthetic enzyme
IM697_17750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IM697_17780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM697_17795	COG2706	6-phosphogluconolactonase activity
IM697_17805	COG2971	BadF BadG BcrA BcrD
IM697_17810	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IM697_17825	COG1960	acyl-CoA dehydrogenase activity
IM697_17845	COG3509	depolymerase
IM697_17850	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IM697_17855	COG1902	pentaerythritol trinitrate reductase activity
IM697_17860	COG0640	Transcriptional regulator
IM697_17870	COG0493	'glutamate synthase
IM697_17890	COG1309	transcriptional regulator
IM697_17895	COG0546	phosphoglycolate phosphatase activity
IM697_17900	COG0671	phosphoesterase, PA-phosphatase related
IM697_17930	COG0584	glycerophosphoryl diester phosphodiesterase
IM697_17955	COG0583	DNA-binding transcription factor activity
IM697_17965	COG0204	Acyl-transferase
IM697_17990	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IM697_18005	COG0515	serine threonine protein kinase
IM697_18215	COG0494	nUDIX hydrolase
IM697_18275	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IM697_18285	COG0105	UTP biosynthetic process
IM697_18670	COG3345	alpha-galactosidase
IM697_18675	COG1090	epimerase
IM697_18685	COG1660	Displays ATPase and GTPase activities
IM697_18715	COG4585	Histidine kinase
IM697_18720	COG2197	response regulator
IM697_18750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IM697_18775	COG2223	nitrite transmembrane transporter activity
IM697_18785	COG0673	inositol 2-dehydrogenase activity
IM697_18795	COG2197	response regulator
IM697_18800	COG4585	Histidine kinase
IM697_18845	COG3594	Acyltransferase
IM697_18875	COG0326	Molecular chaperone. Has ATPase activity
IM697_18890	COG0019	diaminopimelate decarboxylase activity
IM697_18895	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IM697_18900	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IM697_18920	COG1796	DNA polymerase
IM697_18920	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IM697_18945	COG1653	transport
IM697_18950	COG1175	transmembrane transport
IM697_18955	COG0395	ABC-type sugar transport system, permease component
IM697_18975	COG2608	mercury ion transmembrane transporter activity
IM697_18985	COG3387	PFAM Glycoside hydrolase 15-related
IM697_18990	COG1349	DNA-binding transcription factor activity
IM697_18995	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IM697_19005	COG2813	Specifically methylates the guanine in position
IM697_19015	COG1940	carbohydrate kinase activity
IM697_19040	COG1136	(ABC) transporter
IM697_19045	COG0577	efflux transmembrane transporter activity
IM697_19070	COG1349	DNA-binding transcription factor activity
IM697_19105	COG1215	transferase activity, transferring glycosyl groups
IM697_19135	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_19165	COG0142	geranyltranstransferase activity
IM697_19210	COG0574	Belongs to the PEP-utilizing enzyme family
IM697_19210	COG3848	Pyruvate phosphate dikinase
IM697_19270	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IM697_19270	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IM697_19275	COG0726	polysaccharide deacetylase
IM697_19320	COG0583	DNA-binding transcription factor activity
IM697_19330	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_19335	COG0583	DNA-binding transcription factor activity
IM697_19345	COG1053	succinate dehydrogenase
IM697_19350	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IM697_19375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_19380	COG0277	FAD linked oxidase domain protein
IM697_19385	COG2197	response regulator
IM697_19390	COG0523	cobalamin synthesis protein
IM697_19400	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM697_19415	COG3360	Dodecin
IM697_19420	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
IM697_19425	COG0121	glutamine amidotransferase
IM697_19430	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IM697_19485	COG0745	RESPONSE REGULATOR receiver
IM697_19490	COG5002	protein histidine kinase activity
IM697_19495	COG2358	TRAP transporter, solute receptor (TAXI family
IM697_19500	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IM697_19550	COG0583	DNA-binding transcription factor activity
IM697_19565	COG2182	Extracellular solute-binding protein
IM697_19575	COG3833	ABC-type maltose transport systems, permease component
IM697_19665	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_19710	COG2610	gluconate transmembrane transporter activity
IM697_19715	COG4948	Mandelate Racemase Muconate Lactonizing
IM697_19735	COG2353	YceI-like domain
IM697_19740	COG1454	alcohol dehydrogenase
IM697_19745	COG3485	protocatechuate 3,4-dioxygenase
IM697_19755	COG3284	Transcriptional regulator
IM697_19790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IM697_19815	COG2814	Major facilitator Superfamily
IM697_19835	COG0583	DNA-binding transcription factor activity
IM697_19850	COG1609	Transcriptional regulator
IM697_19865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IM697_19875	COG0242	peptide deformylase activity
IM697_19925	COG3507	Belongs to the glycosyl hydrolase 43 family
IM697_19960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM697_19965	COG3345	alpha-galactosidase
IM697_19985	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IM697_19985	COG2124	cytochrome p450
IM697_19995	COG2072	flavoprotein involved in K transport
IM697_20000	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_20005	COG1012	belongs to the aldehyde dehydrogenase family
IM697_20020	COG1595	DNA-templated transcription, initiation
IM697_20025	COG2409	Drug exporters of the RND superfamily
IM697_20050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IM697_20060	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM697_20070	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IM697_20090	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM697_20095	COG1007	ATP synthesis coupled electron transport
IM697_20115	COG2135	peptidase activity
IM697_20125	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IM697_20140	COG1609	Transcriptional regulator
IM697_20175	COG0604	alcohol dehydrogenase
IM697_20175	COG3321	synthase
IM697_20185	COG0542	response to heat
IM697_20195	COG0577	efflux transmembrane transporter activity
IM697_20195	COG1136	(ABC) transporter
IM697_20200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_20200	COG0723	plastoquinol--plastocyanin reductase activity
IM697_20205	COG1556	Lactate utilization protein
IM697_20210	COG1139	Iron-sulfur cluster binding protein
IM697_20215	COG0247	lactate metabolic process
IM697_20220	COG1070	Carbohydrate kinase
IM697_20225	COG3347	Dehydrogenase
IM697_20225	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_20235	COG1129	ABC transporter
IM697_20265	COG1609	Transcriptional regulator
IM697_20280	COG1595	DNA-templated transcription, initiation
IM697_20290	COG1357	PFAM Pentapeptide repeats (8 copies)
IM697_20305	COG2706	6-phosphogluconolactonase activity
IM697_20390	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IM697_20390	COG1796	DNA polymerase
IM697_20420	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IM697_20430	COG1846	Transcriptional regulator
IM697_20490	COG0531	amino acid
IM697_20510	COG0435	Glutathione S-transferase
IM697_20530	COG2124	cytochrome p450
IM697_20550	COG3415	Transposase
IM697_20550	COG2801	Transposase and inactivated derivatives
IM697_20560	COG0667	Aldo Keto reductase
IM697_20590	COG3250	beta-galactosidase activity
IM697_20605	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IM697_20630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IM697_20750	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IM697_20750	COG3608	succinylglutamate desuccinylase aspartoacylase
IM697_20790	COG0789	Transcriptional regulator
IM697_20820	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IM697_20845	COG0019	diaminopimelate decarboxylase activity
IM697_20855	COG2814	Major facilitator Superfamily
IM697_20870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IM697_20875	COG1120	ATPase activity
IM697_20880	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_20885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_20895	COG1132	(ABC) transporter
IM697_20900	COG1937	Protein conserved in bacteria
IM697_20920	COG4221	oxidoreductase activity
IM697_20945	COG2182	Extracellular solute-binding protein
IM697_20950	COG0395	ABC-type sugar transport system, permease component
IM697_20955	COG1175	transmembrane transport
IM697_20960	COG1846	Transcriptional regulator
IM697_20960	COG1940	carbohydrate kinase activity
IM697_21035	COG1940	carbohydrate kinase activity
IM697_21045	COG1175	transmembrane transport
IM697_21050	COG0395	ABC-type sugar transport system, permease component
IM697_21065	COG1072	(Pantothenic acid kinase))
IM697_21075	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IM697_21080	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
IM697_21135	COG0673	inositol 2-dehydrogenase activity
IM697_21145	COG3250	beta-galactosidase activity
IM697_21155	COG1175	transmembrane transport
IM697_21165	COG1609	Transcriptional regulator
IM697_21175	COG0438	transferase activity, transferring glycosyl groups
IM697_21185	COG0702	epimerase
IM697_21260	COG3290	protein histidine kinase activity
IM697_21280	COG2264	protein methyltransferase activity
IM697_21285	COG1132	(ABC) transporter
IM697_21310	COG3739	integral membrane protein
IM697_21355	COG2186	Transcriptional regulator
IM697_21360	COG4948	Mandelate Racemase Muconate Lactonizing
IM697_21370	COG0800	Aldolase
IM697_21400	COG1396	sequence-specific DNA binding
IM697_21425	COG2124	cytochrome p450
IM697_21430	COG2070	2-Nitropropane dioxygenase
IM697_21445	COG2267	carboxylic ester hydrolase activity
IM697_21455	COG2249	NAD(P)H dehydrogenase (quinone) activity
IM697_21470	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IM697_21495	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IM697_21505	COG4941	Belongs to the sigma-70 factor family
IM697_21535	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IM697_21580	COG0187	DNA topoisomerase II activity
IM697_21625	COG0583	DNA-binding transcription factor activity
IM697_21640	COG4106	trans-aconitate 2-methyltransferase activity
IM697_21680	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IM697_21730	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IM697_21750	COG0395	ABC-type sugar transport system, permease component
IM697_21755	COG1175	transmembrane transport
IM697_21760	COG1653	transport
IM697_21770	COG2186	Transcriptional regulator
IM697_21795	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
IM697_21800	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IM697_21800	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IM697_21805	COG3639	organic phosphonate transmembrane transporter activity
IM697_21825	COG1012	belongs to the aldehyde dehydrogenase family
IM697_21845	COG0733	neurotransmitter:sodium symporter activity
IM697_21855	COG0277	FAD linked oxidase domain protein
IM697_21855	COG0247	lactate metabolic process
IM697_21905	COG0659	secondary active sulfate transmembrane transporter activity
IM697_21910	COG4977	sequence-specific DNA binding
IM697_21955	COG1131	(ABC) transporter
IM697_21990	COG0148	phosphopyruvate hydratase activity
IM697_22010	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IM697_22015	COG1349	DNA-binding transcription factor activity
IM697_22055	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IM697_22060	COG0071	Belongs to the small heat shock protein (HSP20) family
IM697_22100	COG1136	(ABC) transporter
IM697_22100	COG0577	efflux transmembrane transporter activity
IM697_22130	COG1595	DNA-templated transcription, initiation
IM697_22155	COG1595	DNA-templated transcription, initiation
IM697_22160	COG0604	alcohol dehydrogenase
IM697_22185	COG0596	Alpha beta hydrolase
IM697_22200	COG2226	methyltransferase
IM697_22250	COG1621	beta-fructofuranosidase activity
IM697_22260	COG1609	Transcriptional regulator
IM697_22270	COG1175	transmembrane transport
IM697_22305	COG0395	ABC-type sugar transport system, permease component
IM697_22325	COG0657	acetylesterase activity
IM697_22345	COG0473	3-isopropylmalate dehydrogenase activity
IM697_22365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IM697_22385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_22400	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IM697_22405	COG1725	Transcriptional regulator
IM697_22430	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IM697_22475	COG2188	Transcriptional regulator
IM697_22500	COG2223	nitrite transmembrane transporter activity
IM697_22510	COG0702	epimerase
IM697_22535	COG0586	Pfam SNARE associated Golgi protein
IM697_22540	COG4585	Histidine kinase
IM697_22600	COG2409	Drug exporters of the RND superfamily
IM697_22610	COG2205	protein histidine kinase activity
IM697_22615	COG0745	RESPONSE REGULATOR receiver
IM697_22650	COG3328	transposase activity
IM697_22765	COG0515	serine threonine protein kinase
IM697_22765	COG2815	serine threonine protein kinase
IM697_22780	COG0515	serine threonine protein kinase
IM697_22780	COG2815	serine threonine protein kinase
IM697_22815	COG3328	transposase activity
IM697_22860	COG1335	isochorismatase
IM697_22880	COG4585	Histidine kinase
IM697_22895	COG2311	Membrane
IM697_22900	COG2311	Membrane
IM697_22910	COG4585	Histidine kinase
IM697_22915	COG2197	response regulator
IM697_22955	COG2311	Membrane
IM697_22965	COG1404	Belongs to the peptidase S8 family
IM697_22970	COG4585	Histidine kinase
IM697_22975	COG2197	response regulator
IM697_22985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM697_23000	COG2311	Membrane
IM697_23025	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM697_23035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM697_23050	COG0154	amidase activity
IM697_23055	COG4166	transmembrane transport
IM697_23060	COG0601	transmembrane transport
IM697_23065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM697_23105	COG3507	Belongs to the glycosyl hydrolase 43 family
IM697_23110	COG1874	Beta-galactosidase
IM697_23120	COG3328	transposase activity
IM697_23130	COG1175	transmembrane transport
IM697_23135	COG0395	ABC-type sugar transport system, permease component
IM697_23160	COG0673	inositol 2-dehydrogenase activity
IM697_23165	COG1172	Belongs to the binding-protein-dependent transport system permease family
IM697_23170	COG1879	ABC-type sugar transport system periplasmic component
IM697_23185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM697_23205	COG0247	lactate metabolic process
IM697_23205	COG0277	FAD linked oxidase domain protein
IM697_23210	COG0583	DNA-binding transcription factor activity
IM697_23220	COG0531	amino acid
IM697_23245	COG2188	Transcriptional regulator
IM697_23255	COG1126	abc transporter atp-binding protein
IM697_23260	COG0765	amino acid transport
IM697_23275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_23280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM697_23295	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_23320	COG1136	(ABC) transporter
IM697_23330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IM697_23340	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IM697_23350	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_23360	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IM697_23390	COG2368	4-hydroxyphenylacetate
IM697_23395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IM697_23400	COG1024	Enoyl-CoA hydratase
IM697_23405	COG1960	acyl-CoA dehydrogenase activity
IM697_23410	COG1024	Enoyl-CoA hydratase
IM697_23420	COG2208	phosphoserine phosphatase activity
IM697_23420	COG1366	Belongs to the anti-sigma-factor antagonist family
IM697_23420	COG2172	sigma factor antagonist activity
IM697_23440	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_23445	COG1024	Enoyl-CoA hydratase
IM697_23450	COG0604	alcohol dehydrogenase
IM697_23450	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_23450	COG3321	synthase
IM697_23465	COG2130	NADP-dependent
IM697_23470	COG0583	DNA-binding transcription factor activity
IM697_23485	COG4249	Peptidase C14 caspase catalytic subunit p20
IM697_23485	COG2319	Wd-40 repeat
IM697_23505	COG3345	alpha-galactosidase
IM697_23520	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IM697_23540	COG0477	Major facilitator Superfamily
IM697_23560	COG0583	DNA-binding transcription factor activity
IM697_23575	COG3290	protein histidine kinase activity
IM697_23580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM697_23585	COG4565	transcriptional regulatory protein
IM697_23650	COG2801	Transposase and inactivated derivatives
IM697_23660	COG0730	response to heat
IM697_23670	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_23675	COG0667	Aldo Keto reductase
IM697_23810	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IM697_23975	COG1012	belongs to the aldehyde dehydrogenase family
IM697_23975	COG1454	alcohol dehydrogenase
IM697_24060	COG0539	negative regulation of cytoplasmic translation
IM697_24070	COG1397	ADP-ribosylglycohydrolase
IM697_24085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM697_24155	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_24195	COG2124	cytochrome p450
IM697_24205	COG2197	response regulator
IM697_24220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IM697_24255	COG1169	isochorismate synthase
IM697_24260	COG1021	2,3-dihydroxybenzoate-AMP ligase
IM697_24265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM697_24265	COG2226	methyltransferase
IM697_24265	COG3433	isochorismatase activity
IM697_24270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM697_24270	COG2226	methyltransferase
IM697_24270	COG3433	isochorismatase activity
IM697_24305	COG1132	(ABC) transporter
IM697_24305	COG2375	cellular response to nickel ion
IM697_24315	COG0477	Major facilitator Superfamily
IM697_24325	COG4172	Belongs to the ABC transporter superfamily
IM697_24375	COG4977	sequence-specific DNA binding
IM697_24460	COG1309	transcriptional regulator
IM697_24490	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_24495	COG2130	NADP-dependent
IM697_24605	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
IM697_24615	COG0488	(ABC) transporter
IM697_24640	COG1032	radical SAM domain protein
IM697_24710	COG3387	PFAM Glycoside hydrolase 15-related
IM697_24740	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IM697_24740	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IM697_24755	COG0725	ABC transporter, periplasmic molybdate-binding protein
IM697_24790	COG0235	Class ii aldolase
IM697_24805	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IM697_24835	COG0277	FAD linked oxidase domain protein
IM697_24855	COG1609	Transcriptional regulator
IM697_24870	COG0596	Alpha beta hydrolase
IM697_24895	COG0659	secondary active sulfate transmembrane transporter activity
IM697_24900	COG0789	Transcriptional regulator
IM697_24970	COG1278	Cold shock
IM697_24975	COG0513	Belongs to the DEAD box helicase family
IM697_25020	COG2267	carboxylic ester hydrolase activity
IM697_25030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM697_25030	COG3320	Male sterility
IM697_25035	COG0604	alcohol dehydrogenase
IM697_25035	COG3321	synthase
IM697_25040	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_25065	COG3845	ABC transporter
IM697_25075	COG2124	cytochrome p450
IM697_25085	COG0009	L-threonylcarbamoyladenylate synthase
IM697_25110	COG1045	serine acetyltransferase
IM697_25155	COG1846	Transcriptional regulator
IM697_25160	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IM697_25170	COG1918	ferrous iron import across plasma membrane
IM697_25170	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
IM697_25180	COG3559	Exporter of polyketide antibiotics
IM697_25185	COG1131	(ABC) transporter
IM697_25200	COG1595	DNA-templated transcription, initiation
IM697_25205	COG2814	Major facilitator Superfamily
IM697_25215	COG0596	Alpha beta hydrolase
IM697_25240	COG3629	intracellular signal transduction
IM697_25240	COG3903	Transcriptional regulator
IM697_25275	COG3903	Transcriptional regulator
IM697_25275	COG3629	intracellular signal transduction
IM697_25290	COG0596	Alpha beta hydrolase
IM697_25300	COG1621	beta-fructofuranosidase activity
IM697_25310	COG1175	transmembrane transport
IM697_25315	COG0395	ABC-type sugar transport system, permease component
IM697_25325	COG1609	Transcriptional regulator
IM697_25330	COG0656	L-ascorbic acid biosynthetic process
IM697_25340	COG3547	Transposase (IS116 IS110 IS902 family)
IM697_25360	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IM697_25420	COG2207	Transcriptional regulator
IM697_25425	COG2223	nitrite transmembrane transporter activity
IM697_25435	COG2197	response regulator
IM697_25460	COG2814	Major facilitator Superfamily
IM697_25465	COG0181	hydroxymethylbilane synthase activity
IM697_25505	COG0366	Alpha amylase catalytic
IM697_25515	COG3281	Trehalose synthase
IM697_25520	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IM697_25585	COG5002	protein histidine kinase activity
IM697_25625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM697_25660	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
IM697_25660	COG1672	PFAM Archaeal ATPase
IM697_25675	COG3345	alpha-galactosidase
IM697_25680	COG1846	Transcriptional regulator
IM697_25680	COG1940	carbohydrate kinase activity
IM697_25690	COG2340	Cysteine-rich secretory protein family
IM697_25705	COG0142	geranyltranstransferase activity
IM697_25715	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IM697_25715	COG0515	serine threonine protein kinase
IM697_25725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_25740	COG0667	Aldo Keto reductase
IM697_25760	COG2304	oxidoreductase activity
IM697_25765	COG0328	RNA-DNA hybrid ribonuclease activity
IM697_25780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IM697_25790	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IM697_25805	COG0596	Alpha beta hydrolase
IM697_25810	COG0740	serine-type endopeptidase activity
IM697_25815	COG0740	serine-type endopeptidase activity
IM697_25820	COG1396	sequence-specific DNA binding
IM697_25840	COG2815	serine threonine protein kinase
IM697_25840	COG0515	serine threonine protein kinase
IM697_25850	COG0842	Transport permease protein
IM697_25850	COG1716	ATPase activity
IM697_25850	COG1131	(ABC) transporter
IM697_25870	COG0667	Aldo Keto reductase
IM697_25875	COG0583	DNA-binding transcription factor activity
IM697_25885	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IM697_25890	COG0346	lactoylglutathione lyase activity
IM697_25905	COG0667	Aldo Keto reductase
IM697_25915	COG4941	Belongs to the sigma-70 factor family
IM697_25930	COG0640	Transcriptional regulator
IM697_26035	COG0589	response to stress
IM697_26060	COG1024	Enoyl-CoA hydratase
IM697_26095	COG1840	ABC-type Fe3 transport system, periplasmic component
IM697_26100	COG1178	ABC-type Fe3 transport system permease component
IM697_26105	COG3842	ATPase activity
IM697_26120	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_26125	COG2366	antibiotic biosynthetic process
IM697_26130	COG2124	cytochrome p450
IM697_26150	COG2070	2-Nitropropane dioxygenase
IM697_26155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM697_26175	COG0515	serine threonine protein kinase
IM697_26185	COG1960	acyl-CoA dehydrogenase activity
IM697_26205	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IM697_26215	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IM697_26225	COG2326	polyphosphate kinase activity
IM697_26240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM697_26245	COG5006	permease, DMT superfamily
IM697_26255	COG0574	Belongs to the PEP-utilizing enzyme family
IM697_26255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IM697_26275	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
IM697_26295	COG0543	2 iron, 2 sulfur cluster binding
IM697_26310	COG0516	GMP reductase activity
IM697_26310	COG0517	IMP dehydrogenase activity
IM697_26320	COG0309	Hydrogenase expression formation protein (HypE)
IM697_26340	COG0517	IMP dehydrogenase activity
IM697_26340	COG0516	GMP reductase activity
IM697_26345	COG1042	CoA-binding domain protein
IM697_26345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM697_26345	COG0045	succinate-CoA ligase (ADP-forming) activity
IM697_26350	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
IM697_26355	COG0589	response to stress
IM697_26375	COG0549	Belongs to the carbamate kinase family
IM697_26400	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IM697_26470	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IM697_26475	COG0674	pyruvate-flavodoxin oxidoreductase activity
IM697_26480	COG1013	pyruvate-flavodoxin oxidoreductase activity
IM697_26485	COG0493	'glutamate synthase
IM697_26495	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IM697_26515	COG1063	alcohol dehydrogenase
IM697_26545	COG0205	6-phosphofructokinase activity
IM697_26560	COG2376	Dihydroxyacetone kinase
IM697_26565	COG1461	Dihydroxyacetone kinase
IM697_26580	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_26605	COG0446	pyridine nucleotide-disulphide oxidoreductase
IM697_26605	COG1902	pentaerythritol trinitrate reductase activity
IM697_26610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM697_26635	COG2890	protein-(glutamine-N5) methyltransferase activity
IM697_26640	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IM697_26655	COG3458	cephalosporin-C deacetylase activity
IM697_26660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM697_26665	COG2188	Transcriptional regulator
IM697_26670	COG2226	methyltransferase
IM697_26675	COG1695	Transcriptional regulator
IM697_26685	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IM697_26700	COG2066	Belongs to the glutaminase family
IM697_26715	COG1113	amino acid transport
IM697_26720	COG2186	Transcriptional regulator
IM697_26725	COG1968	undecaprenyl-diphosphatase activity
IM697_26730	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IM697_26735	COG1993	acr, cog1993
IM697_26740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IM697_26785	COG1175	transmembrane transport
IM697_26790	COG0395	ABC-type sugar transport system, permease component
IM697_26820	COG1960	acyl-CoA dehydrogenase activity
IM697_26825	COG3340	Belongs to the peptidase S51 family
IM697_26860	COG3291	Pkd domain containing protein
IM697_26865	COG0583	DNA-binding transcription factor activity
IM697_26880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IM697_26885	COG0583	DNA-binding transcription factor activity
IM697_26890	COG2851	Citrate transporter
IM697_26900	COG0028	Belongs to the TPP enzyme family
IM697_26905	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
IM697_26920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IM697_26925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_26930	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_26945	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IM697_26965	COG2340	Cysteine-rich secretory protein family
IM697_26970	COG0477	Major facilitator Superfamily
IM697_26990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IM697_26995	COG1181	Belongs to the D-alanine--D-alanine ligase family
IM697_27020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM697_27140	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IM697_27160	COG2132	Multicopper oxidase
IM697_27185	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IM697_27215	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_27220	COG4948	Mandelate Racemase Muconate Lactonizing
IM697_27230	COG1129	ABC transporter
IM697_27235	COG1879	ABC-type sugar transport system periplasmic component
IM697_27255	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM697_27295	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_27340	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IM697_27345	COG0297	glycogen (starch) synthase activity
IM697_27365	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IM697_27385	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IM697_27400	COG0475	glutathione-regulated potassium exporter activity
IM697_27415	COG0492	ferredoxin-NADP+ reductase activity
IM697_27435	COG1129	ABC transporter
IM697_27440	COG1172	Belongs to the binding-protein-dependent transport system permease family
IM697_27455	COG1132	(ABC) transporter
IM697_27465	COG1024	Enoyl-CoA hydratase
IM697_27470	COG0668	transmembrane transport
IM697_27480	COG2838	Isocitrate dehydrogenase
IM697_27525	COG1846	Transcriptional regulator
IM697_27530	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IM697_27535	COG1012	belongs to the aldehyde dehydrogenase family
IM697_27550	COG0179	Fumarylacetoacetate (FAA) hydrolase
IM697_27565	COG4689	acetoacetate decarboxylase
IM697_27580	COG0174	glutamine synthetase
IM697_27610	COG1116	anion transmembrane transporter activity
IM697_27615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IM697_27620	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IM697_27625	COG1414	Transcriptional regulator
IM697_27690	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IM697_27700	COG1609	Transcriptional regulator
IM697_27705	COG0673	inositol 2-dehydrogenase activity
IM697_27710	COG0673	inositol 2-dehydrogenase activity
IM697_27715	COG0673	inositol 2-dehydrogenase activity
IM697_27730	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_27735	COG0673	inositol 2-dehydrogenase activity
IM697_27740	COG0673	inositol 2-dehydrogenase activity
IM697_27745	COG0673	inositol 2-dehydrogenase activity
IM697_27770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM697_27780	COG3718	enzyme involved in inositol metabolism
IM697_27785	COG3962	Belongs to the TPP enzyme family
IM697_27795	COG2188	Transcriptional regulator
IM697_27810	COG0494	nUDIX hydrolase
IM697_27830	COG0022	dehydrogenase e1 component
IM697_27835	COG1012	belongs to the aldehyde dehydrogenase family
IM697_27845	COG2770	Histidine kinase
IM697_27845	COG2208	phosphoserine phosphatase activity
IM697_27905	COG2267	carboxylic ester hydrolase activity
IM697_27940	COG0402	S-adenosylhomocysteine deaminase activity
IM697_27945	COG0022	dehydrogenase e1 component
IM697_27950	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IM697_27955	COG0006	proline dipeptidase activity
IM697_27975	COG1136	(ABC) transporter
IM697_27985	COG2197	response regulator
IM697_28010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM697_28050	COG2815	serine threonine protein kinase
IM697_28050	COG0515	serine threonine protein kinase
IM697_28060	COG0515	serine threonine protein kinase
IM697_28080	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IM697_28100	COG1012	belongs to the aldehyde dehydrogenase family
IM697_28180	COG2824	Alkylphosphonate utilization operon protein PhnA
IM697_28200	COG0659	secondary active sulfate transmembrane transporter activity
IM697_28210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IM697_28245	COG2132	Multicopper oxidase
IM697_28250	COG0535	radical SAM domain protein
IM697_28260	COG1140	nitrate reductase beta subunit
IM697_28265	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IM697_28275	COG1017	nitric oxide dioxygenase activity
IM697_28275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IM697_28285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IM697_28300	COG2197	response regulator
IM697_28305	COG4585	Histidine kinase
IM697_28330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM697_28345	COG0583	DNA-binding transcription factor activity
IM697_28350	COG0156	8-amino-7-oxononanoate synthase activity
IM697_28355	COG1063	alcohol dehydrogenase
IM697_28405	COG2755	lipolytic protein G-D-S-L family
IM697_28420	COG2365	Tyrosine phosphatase family
IM697_28440	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IM697_28445	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IM697_28460	COG1657	PFAM Prenyltransferase squalene oxidase
IM697_28470	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IM697_28480	COG1562	ergosterol biosynthetic process
IM697_28485	COG1134	teichoic acid transport
IM697_28530	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IM697_28535	COG2801	Transposase and inactivated derivatives
IM697_28535	COG3415	Transposase
IM697_28545	COG1024	Enoyl-CoA hydratase
IM697_28565	COG2183	response to ionizing radiation
IM697_28575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM697_28580	COG0488	(ABC) transporter
IM697_28590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IM697_28600	COG2936	dipeptidyl-peptidase activity
IM697_28610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM697_28615	COG1113	amino acid transport
IM697_28625	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM697_28625	COG1024	Enoyl-CoA hydratase
IM697_28630	COG0183	Belongs to the thiolase family
IM697_28635	COG1960	acyl-CoA dehydrogenase activity
IM697_28640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IM697_28650	COG3268	Saccharopine dehydrogenase
IM697_28685	COG0488	(ABC) transporter
IM697_28695	COG1834	amidinotransferase
IM697_28740	COG1793	dna ligase
IM697_28770	COG0183	Belongs to the thiolase family
IM697_28775	COG3485	protocatechuate 3,4-dioxygenase
IM697_28780	COG3485	protocatechuate 3,4-dioxygenase
IM697_28785	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IM697_28790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IM697_28800	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
IM697_28800	COG1672	PFAM Archaeal ATPase
IM697_28810	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IM697_28835	COG3511	phospholipase C
IM697_28845	COG1082	Xylose isomerase domain protein TIM barrel
IM697_28860	COG1129	ABC transporter
IM697_28870	COG2197	response regulator
IM697_28890	COG1136	(ABC) transporter
IM697_28900	COG3328	transposase activity
IM697_28915	COG3693	PFAM glycoside hydrolase, family 10
IM697_28935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM697_28940	COG0179	Fumarylacetoacetate (FAA) hydrolase
IM697_28950	COG1414	Transcriptional regulator
IM697_29080	COG1414	Transcriptional regulator
IM697_29090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IM697_29095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IM697_29100	COG1116	anion transmembrane transporter activity
IM697_29110	COG1802	Transcriptional regulator
IM697_29115	COG3938	Belongs to the proline racemase family
IM697_29120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM697_29135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_29165	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IM697_29175	COG3469	chitinase activity
IM697_29190	COG1486	melibiose metabolic process
IM697_29200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM697_29210	COG1175	transmembrane transport
IM697_29220	COG3250	beta-galactosidase activity
IM697_29225	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IM697_29260	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_29275	COG4585	Histidine kinase
IM697_29280	COG2197	response regulator
IM697_29285	COG2409	Drug exporters of the RND superfamily
IM697_29315	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IM697_29330	COG0166	Belongs to the GPI family
IM697_29335	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IM697_29340	COG0406	alpha-ribazole phosphatase activity
IM697_29350	COG1082	Xylose isomerase domain protein TIM barrel
IM697_29350	COG3185	4-Hydroxyphenylpyruvate dioxygenase
IM697_29355	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IM697_29365	COG0477	Major facilitator Superfamily
IM697_29380	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IM697_29390	COG0438	transferase activity, transferring glycosyl groups
IM697_29410	COG3415	Transposase
IM697_29410	COG2801	Transposase and inactivated derivatives
IM697_29415	COG3467	pyridoxamine 5'-phosphate
IM697_29425	COG0477	Major facilitator Superfamily
IM697_29440	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IM697_29455	COG0438	transferase activity, transferring glycosyl groups
IM697_29485	COG0747	negative chemotaxis
IM697_29505	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IM697_29530	COG3433	isochorismatase activity
IM697_29530	COG1535	isochorismatase
IM697_29535	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IM697_29555	COG2382	esterase
IM697_29560	COG1132	(ABC) transporter
IM697_29570	COG1132	(ABC) transporter
IM697_29580	COG1120	ATPase activity
IM697_29585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_29590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_29595	COG3486	L-lysine 6-monooxygenase (NADPH) activity
IM697_29610	COG0300	oxidoreductase activity
IM697_29610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM697_29610	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_29610	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_29610	COG3321	synthase
IM697_29620	COG1131	(ABC) transporter
IM697_29650	COG1012	belongs to the aldehyde dehydrogenase family
IM697_29660	COG0045	succinate-CoA ligase (ADP-forming) activity
IM697_29670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IM697_29680	COG2223	nitrite transmembrane transporter activity
IM697_29745	COG0673	inositol 2-dehydrogenase activity
IM697_29755	COG1172	Belongs to the binding-protein-dependent transport system permease family
IM697_29760	COG1129	ABC transporter
IM697_29765	COG1940	carbohydrate kinase activity
IM697_29775	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IM697_29785	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IM697_29790	COG3383	formate dehydrogenase (NAD+) activity
IM697_29805	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IM697_29810	COG1335	isochorismatase
IM697_29840	COG0656	L-ascorbic acid biosynthetic process
IM697_29850	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IM697_29860	COG5297	Belongs to the glycosyl hydrolase family 6
IM697_29865	COG5297	Belongs to the glycosyl hydrolase family 6
IM697_29865	COG4733	cellulase activity
IM697_29875	COG3401	FG-GAP repeat protein
IM697_29880	COG4106	trans-aconitate 2-methyltransferase activity
IM697_29880	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IM697_29885	COG2154	pterin-4-alpha-carbinolamine dehydratase
IM697_29915	COG1140	nitrate reductase beta subunit
IM697_29930	COG0443	Heat shock 70 kDa protein
IM697_29990	COG0028	Belongs to the TPP enzyme family
IM697_30000	COG0516	GMP reductase activity
IM697_30000	COG0517	IMP dehydrogenase activity
IM697_30005	COG0693	protein deglycase activity
IM697_30025	COG0488	(ABC) transporter
IM697_30030	COG0406	alpha-ribazole phosphatase activity
IM697_30035	COG1597	lipid kinase activity
IM697_30040	COG2226	methyltransferase
IM697_30100	COG1793	dna ligase
IM697_30100	COG3285	dna ligase
IM697_30115	COG4948	Mandelate Racemase Muconate Lactonizing
IM697_30125	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_30155	COG1619	proteins homologs of microcin C7 resistance protein MccF
IM697_30165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM697_30170	COG2362	D-Aminopeptidase
IM697_30175	COG0310	cobalt ion transport
IM697_30180	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
IM697_30190	COG1122	ATPase activity
IM697_30220	COG2226	methyltransferase
IM697_30225	COG2172	sigma factor antagonist activity
IM697_30225	COG2208	phosphoserine phosphatase activity
IM697_30225	COG1366	Belongs to the anti-sigma-factor antagonist family
IM697_30245	COG0596	Alpha beta hydrolase
IM697_30260	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM697_30275	COG0604	alcohol dehydrogenase
IM697_30280	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IM697_30280	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IM697_30295	COG1960	acyl-CoA dehydrogenase activity
IM697_30300	COG0688	phosphatidylethanolamine metabolic process
IM697_30325	COG0559	Belongs to the binding-protein-dependent transport system permease family
IM697_30330	COG0559	Belongs to the binding-protein-dependent transport system permease family
IM697_30350	COG1929	Belongs to the glycerate kinase type-1 family
IM697_30370	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IM697_30390	COG0640	Transcriptional regulator
IM697_30430	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IM697_30485	COG3940	Belongs to the glycosyl hydrolase 43 family
IM697_30540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IM697_30545	COG1120	ATPase activity
IM697_30550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM697_30575	COG0723	plastoquinol--plastocyanin reductase activity
IM697_30575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_30585	COG0667	Aldo Keto reductase
IM697_30590	COG1012	belongs to the aldehyde dehydrogenase family
IM697_30595	COG3608	succinylglutamate desuccinylase aspartoacylase
IM697_30600	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IM697_30615	COG3842	ATPase activity
IM697_30630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_30635	COG1414	Transcriptional regulator
IM697_30640	COG1414	Transcriptional regulator
IM697_30655	COG0277	FAD linked oxidase domain protein
IM697_30655	COG0247	lactate metabolic process
IM697_30660	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IM697_30670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_30685	COG0251	oxidation-reduction process
IM697_30695	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_30705	COG3842	ATPase activity
IM697_30725	COG0723	plastoquinol--plastocyanin reductase activity
IM697_30725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_30735	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_30740	COG0477	Major facilitator Superfamily
IM697_30765	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_30775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM697_30785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM697_30790	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_30805	COG0477	Major facilitator Superfamily
IM697_30865	COG0483	inositol monophosphate 1-phosphatase activity
IM697_30875	COG1309	transcriptional regulator
IM697_30880	COG1131	(ABC) transporter
IM697_30910	COG3848	Pyruvate phosphate dikinase
IM697_30910	COG0574	Belongs to the PEP-utilizing enzyme family
IM697_30915	COG0500	methyltransferase
IM697_30925	COG0604	alcohol dehydrogenase
IM697_30925	COG3321	synthase
IM697_30930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM697_30935	COG0156	8-amino-7-oxononanoate synthase activity
IM697_30940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM697_30945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM697_30950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IM697_30955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM697_30960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM697_30965	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IM697_30995	COG1960	acyl-CoA dehydrogenase activity
IM697_31005	COG3629	intracellular signal transduction
IM697_31030	COG2208	phosphoserine phosphatase activity
IM697_31055	COG1120	ATPase activity
IM697_31060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM697_31075	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IM697_31080	COG2226	methyltransferase
IM697_31085	COG1024	Enoyl-CoA hydratase
IM697_31105	COG2197	response regulator
IM697_31125	COG1953	Uracil, thiamine, allantoin
IM697_31135	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IM697_31175	COG0542	response to heat
IM697_31180	COG0405	Gamma-glutamyltransferase
IM697_31215	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IM697_31230	COG3328	transposase activity
IM697_31245	COG2801	Transposase and inactivated derivatives
IM697_31245	COG3415	Transposase
IM697_31295	COG0604	alcohol dehydrogenase
IM697_31295	COG3321	synthase
IM697_31310	COG2267	carboxylic ester hydrolase activity
IM697_31320	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IM697_31365	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IM697_31375	COG1940	carbohydrate kinase activity
IM697_31380	COG2188	Transcriptional regulator
IM697_31385	COG0673	inositol 2-dehydrogenase activity
IM697_31395	COG2197	response regulator
IM697_31425	COG1104	cysteine desulfurase activity
IM697_31440	COG2814	Major facilitator Superfamily
IM697_31500	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IM697_31505	COG1802	Transcriptional regulator
IM697_31515	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_31520	COG4266	Belongs to the allantoicase family
IM697_31525	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IM697_31530	COG1414	Transcriptional regulator
IM697_31545	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IM697_31565	COG4264	IucA IucC family
IM697_31570	COG2304	oxidoreductase activity
IM697_31580	COG1733	regulation of RNA biosynthetic process
IM697_31585	COG0436	Aminotransferase
IM697_31595	COG0406	alpha-ribazole phosphatase activity
IM697_31610	COG2233	PERMEase
IM697_31625	COG2351	hydroxyisourate hydrolase activity
IM697_31660	COG3622	Belongs to the hyi family
IM697_31665	COG2084	Dehydrogenase
IM697_31670	COG0753	catalase activity
IM697_31675	COG3960	tartronate-semialdehyde synthase activity
IM697_31695	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_31700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IM697_31705	COG2197	response regulator
IM697_31720	COG1280	lysine exporter protein (LysE YggA)
IM697_31730	COG0598	Magnesium transport protein CorA
IM697_31750	COG0589	response to stress
IM697_31755	COG2814	Major facilitator Superfamily
IM697_31760	COG0673	inositol 2-dehydrogenase activity
IM697_31765	COG1609	Transcriptional regulator
IM697_31770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM697_31785	COG3962	Belongs to the TPP enzyme family
IM697_31795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM697_31805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM697_31810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM697_31825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IM697_31830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM697_31835	COG1937	Protein conserved in bacteria
IM697_31840	COG0730	response to heat
IM697_31845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM697_31850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM697_31850	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM697_31895	COG2197	response regulator
IM697_31930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM697_31945	COG0179	Fumarylacetoacetate (FAA) hydrolase
IM697_31970	COG0583	DNA-binding transcription factor activity
IM697_32010	COG3940	Belongs to the glycosyl hydrolase 43 family
IM697_32020	COG3608	succinylglutamate desuccinylase aspartoacylase
IM697_32020	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IM697_32025	COG2252	PERMEase
IM697_32030	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IM697_32045	COG3835	regulator
IM697_32055	COG1802	Transcriptional regulator
IM697_32110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IM697_32120	COG1162	GTPase activity
IM697_32145	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IM697_32150	COG0277	FAD linked oxidase domain protein
IM697_32165	COG1175	transmembrane transport
IM697_32170	COG0395	ABC-type sugar transport system, permease component
IM697_32180	COG1131	(ABC) transporter
IM697_32225	COG4585	Histidine kinase
IM697_32230	COG2197	response regulator
IM697_32275	COG2040	homocysteine
IM697_32280	COG1609	Transcriptional regulator
IM697_32305	COG0395	ABC-type sugar transport system, permease component
IM697_32310	COG1175	transmembrane transport
IM697_32325	COG1609	Transcriptional regulator
IM697_32335	COG1175	transmembrane transport
IM697_32340	COG0395	ABC-type sugar transport system, permease component
IM697_32390	COG1917	Cupin 2, conserved barrel domain protein
IM697_32390	COG4977	sequence-specific DNA binding
IM697_32405	COG1960	acyl-CoA dehydrogenase activity
IM697_32430	COG0175	sulfate reduction
IM697_32435	COG0529	Catalyzes the synthesis of activated sulfate
IM697_32460	COG1116	anion transmembrane transporter activity
IM697_32465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IM697_32480	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IM697_32505	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IM697_32520	COG1175	transmembrane transport
IM697_32530	COG0583	DNA-binding transcription factor activity
IM697_32615	COG1280	lysine exporter protein (LysE YggA)
IM697_32620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM697_32645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IM697_32655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IM697_32685	COG1404	Belongs to the peptidase S8 family
IM697_32750	COG2018	Roadblock/LC7 domain
IM697_32775	COG1174	glycine betaine transport
IM697_32785	COG2205	protein histidine kinase activity
IM697_32790	COG0745	RESPONSE REGULATOR receiver
IM697_32830	COG3284	Transcriptional regulator
IM697_32835	COG1073	alpha beta
IM697_32855	COG4821	SIS domain
IM697_32860	COG1737	Transcriptional regulator
IM697_32880	COG1175	transmembrane transport
IM697_32885	COG0395	ABC-type sugar transport system, permease component
IM697_32905	COG1472	Belongs to the glycosyl hydrolase 3 family
IM697_32920	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IM697_32925	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IM697_32960	COG0330	HflC and HflK could
IM697_32990	COG4152	abc transporter atp-binding protein
IM697_33000	COG3220	belongs to the UPF0276 family
IM697_33020	COG3253	May function as heme-dependent peroxidase
IM697_33025	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IM697_33035	COG0446	pyridine nucleotide-disulphide oxidoreductase
IM697_33060	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IM697_33075	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IM697_33085	COG1175	transmembrane transport
IM697_33095	COG3250	beta-galactosidase activity
IM697_33100	COG1609	Transcriptional regulator
IM697_33105	COG0183	Belongs to the thiolase family
IM697_33110	COG1024	Enoyl-CoA hydratase
IM697_33110	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM697_33125	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IM697_33130	COG1316	TRANSCRIPTIONal
IM697_33155	COG0531	amino acid
IM697_33160	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IM697_33165	COG4214	carbohydrate transport
IM697_33175	COG4213	ABC transporter substrate-binding protein
IM697_33180	COG1940	carbohydrate kinase activity
IM697_33185	COG0395	ABC-type sugar transport system, permease component
IM697_33190	COG1175	transmembrane transport
IM697_33195	COG1653	transport
IM697_33220	COG1653	transport
IM697_33225	COG0395	ABC-type sugar transport system, permease component
IM697_33230	COG4209	transmembrane transport
IM697_33235	COG3458	cephalosporin-C deacetylase activity
IM697_33260	COG2205	protein histidine kinase activity
IM697_33265	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IM697_33270	COG0137	argininosuccinate synthase activity
IM697_33275	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IM697_33285	COG2197	response regulator
IM697_33290	COG4585	Histidine kinase
IM697_33345	COG1024	Enoyl-CoA hydratase
IM697_33355	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IM697_33360	COG2235	arginine
IM697_33375	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IM697_33410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IM697_33415	COG1799	cell septum assembly
IM697_33420	COG0243	molybdopterin cofactor binding
IM697_33435	COG0247	lactate metabolic process
IM697_33435	COG0277	FAD linked oxidase domain protein
IM697_33450	COG4221	oxidoreductase activity
IM697_33470	COG1674	ftsk spoiiie
IM697_33485	COG0569	domain protein
IM697_33490	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IM697_33505	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IM697_33510	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IM697_33515	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IM697_33530	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IM697_33550	COG0367	asparagine synthase
IM697_33585	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IM697_33600	COG4310	Domain of unknown function (DUF2172)
IM697_33610	COG1215	transferase activity, transferring glycosyl groups
IM697_33625	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IM697_33680	COG0477	Major facilitator Superfamily
IM697_33705	COG0583	DNA-binding transcription factor activity
IM697_33715	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_33725	COG0492	ferredoxin-NADP+ reductase activity
IM697_33730	COG3118	belongs to the thioredoxin family
IM697_33750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IM697_33755	COG0531	amino acid
IM697_33760	COG0569	domain protein
IM697_33800	COG0756	dUTP diphosphatase activity
IM697_33825	COG2205	protein histidine kinase activity
IM697_33830	COG0745	RESPONSE REGULATOR receiver
IM697_33840	COG0483	inositol monophosphate 1-phosphatase activity
IM697_33845	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IM697_33890	COG0542	response to heat
IM697_33895	COG1435	thymidine kinase activity
IM697_33915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM697_33920	COG1802	Transcriptional regulator
IM697_33935	COG0612	Peptidase, M16
IM697_33940	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IM697_33945	COG0523	cobalamin synthesis protein
IM697_33965	COG0372	Belongs to the citrate synthase family
IM697_33980	COG3290	protein histidine kinase activity
IM697_33985	COG4565	transcriptional regulatory protein
IM697_33990	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM697_34000	COG0187	DNA topoisomerase II activity
IM697_34020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IM697_34025	COG1802	Transcriptional regulator
IM697_34050	COG0514	ATP-dependent DNA helicase (RecQ)
IM697_34065	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IM697_34085	COG0588	phosphoglycerate mutase activity
IM697_34100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IM697_34105	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IM697_34110	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IM697_34135	COG0531	amino acid
IM697_34140	COG4977	sequence-specific DNA binding
IM697_34155	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IM697_34165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IM697_34170	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IM697_34180	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IM697_34200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IM697_34220	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IM697_34230	COG3321	synthase
IM697_34230	COG0604	alcohol dehydrogenase
IM697_34230	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_34240	COG2358	TRAP transporter, solute receptor (TAXI family
IM697_34245	COG2205	protein histidine kinase activity
IM697_34250	COG0745	RESPONSE REGULATOR receiver
IM697_34255	COG1126	abc transporter atp-binding protein
IM697_34260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM697_34265	COG0765	amino acid transport
IM697_34270	COG0765	amino acid transport
IM697_34295	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IM697_34310	COG0628	permease
IM697_34335	COG2207	Transcriptional regulator
IM697_34335	COG1917	Cupin 2, conserved barrel domain protein
IM697_34340	COG1201	RNA secondary structure unwinding
IM697_34345	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IM697_34350	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_34360	COG1396	sequence-specific DNA binding
IM697_34365	COG1058	Belongs to the CinA family
IM697_34365	COG1546	Belongs to the CinA family
IM697_34375	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IM697_34385	COG1674	ftsk spoiiie
IM697_34395	COG3850	Histidine kinase
IM697_34395	COG3437	response regulator, receiver
IM697_34395	COG4999	Histidine kinase
IM697_34395	COG2205	protein histidine kinase activity
IM697_34400	COG2208	phosphoserine phosphatase activity
IM697_34400	COG2770	Histidine kinase
IM697_34430	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IM697_34435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM697_34440	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
IM697_34460	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IM697_34465	COG0612	Peptidase, M16
IM697_34470	COG1185	polyribonucleotide nucleotidyltransferase activity
IM697_34475	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IM697_34485	COG1674	ftsk spoiiie
IM697_34695	COG1404	Belongs to the peptidase S8 family
IM697_34710	COG1404	Belongs to the peptidase S8 family
IM697_34740	COG0455	bacterial-type flagellum organization
IM697_34755	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IM697_34760	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IM697_34770	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IM697_34785	COG0779	Required for maturation of 30S ribosomal subunits
IM697_34805	COG0442	prolyl-tRNA aminoacylation
IM697_34820	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IM697_34825	COG0750	zinc metalloprotease
IM697_34830	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IM697_34875	COG0395	ABC-type sugar transport system, permease component
IM697_34880	COG4209	transmembrane transport
IM697_34885	COG1653	transport
IM697_34895	COG1012	belongs to the aldehyde dehydrogenase family
IM697_34930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM697_34935	COG1177	transmembrane transport
IM697_34940	COG1176	ABC-type spermidine putrescine transport system, permease component I
IM697_34945	COG3842	ATPase activity
IM697_34970	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IM697_34975	COG0584	glycerophosphoryl diester phosphodiesterase
IM697_35000	COG1012	belongs to the aldehyde dehydrogenase family
IM697_35010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IM697_35015	COG1136	(ABC) transporter
IM697_35045	COG3842	ATPase activity
IM697_35050	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IM697_35060	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IM697_35090	COG0575	Belongs to the CDS family
IM697_35095	COG0233	cytoplasmic translational termination
IM697_35100	COG0528	UMP kinase activity
IM697_35110	COG0052	Belongs to the universal ribosomal protein uS2 family
IM697_35125	COG1191	sigma factor activity
IM697_35140	COG0792	nuclease activity
IM697_35160	COG0681	Belongs to the peptidase S26 family
IM697_35170	COG0681	Belongs to the peptidase S26 family
IM697_35175	COG0335	large ribosomal subunit rRNA binding
IM697_35180	COG0336	Belongs to the RNA methyltransferase TrmD family
IM697_35185	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IM697_35190	COG1837	Belongs to the UPF0109 family
IM697_35195	COG0228	four-way junction DNA binding
IM697_35210	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IM697_35220	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IM697_35255	COG0477	Major facilitator Superfamily
IM697_35260	COG1196	nuclear chromosome segregation
IM697_35270	COG1254	Belongs to the acylphosphatase family
IM697_35275	COG2340	Cysteine-rich secretory protein family
IM697_35280	COG1733	regulation of RNA biosynthetic process
IM697_35285	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IM697_35290	COG0571	ribonuclease III activity
IM697_35295	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IM697_35310	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IM697_35315	COG0742	ribosomal rna small subunit methyltransferase
IM697_35325	COG0326	Molecular chaperone. Has ATPase activity
IM697_35335	COG1461	Dihydroxyacetone kinase
IM697_35340	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IM697_35345	COG0351	phosphomethylpyrimidine kinase
IM697_35365	COG1181	Belongs to the D-alanine--D-alanine ligase family
IM697_35370	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IM697_35385	COG0776	regulation of translation
IM697_35395	COG0066	3-isopropylmalate dehydratase activity
IM697_35400	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IM697_35405	COG1414	Transcriptional regulator
IM697_35455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IM697_35460	COG0179	Fumarylacetoacetate (FAA) hydrolase
IM697_35480	COG5002	protein histidine kinase activity
IM697_35485	COG2018	Roadblock/LC7 domain
IM697_35505	COG2018	Roadblock/LC7 domain
IM697_35530	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IM697_35535	COG5492	domain, Protein
IM697_35540	COG2353	YceI-like domain
IM697_35565	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM697_35590	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IM697_35605	COG2957	Belongs to the agmatine deiminase family
IM697_35610	COG0804	urea catabolic process
IM697_35615	COG0832	Belongs to the urease beta subunit family
IM697_35615	COG0831	urea catabolic process
IM697_35625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IM697_35630	COG0473	3-isopropylmalate dehydrogenase activity
IM697_35660	COG1012	belongs to the aldehyde dehydrogenase family
IM697_35665	COG0506	proline dehydrogenase activity
IM697_35670	COG3835	regulator
IM697_35675	COG0747	negative chemotaxis
IM697_35680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM697_35690	COG4608	Belongs to the ABC transporter superfamily
IM697_35705	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IM697_35710	COG0440	acetolactate synthase activity
IM697_35720	COG5001	Diguanylate cyclase
IM697_35730	COG0667	Aldo Keto reductase
IM697_35735	COG2133	pyrroloquinoline quinone binding
IM697_35745	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
IM697_35745	COG1672	PFAM Archaeal ATPase
IM697_35760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM697_35765	COG2409	Drug exporters of the RND superfamily
IM697_35780	COG2226	methyltransferase
IM697_35785	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IM697_35795	COG0154	amidase activity
IM697_35800	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IM697_35820	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IM697_35830	COG4221	oxidoreductase activity
IM697_35845	COG0596	Alpha beta hydrolase
IM697_35850	COG0482	sulfurtransferase activity
IM697_35855	COG3023	N-Acetylmuramoyl-L-alanine amidase
IM697_35895	COG2860	membrane
IM697_35905	COG0444	Belongs to the ABC transporter superfamily
IM697_35915	COG4166	transmembrane transport
IM697_35920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM697_35940	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IM697_35945	COG0509	glycine decarboxylation via glycine cleavage system
IM697_35950	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IM697_35955	COG1760	l-serine dehydratase
IM697_35970	COG3409	Peptidoglycan-binding domain 1 protein
IM697_35970	COG3757	hydrolase, family 25
IM697_35980	COG0789	Transcriptional regulator
IM697_36005	COG1024	Enoyl-CoA hydratase
IM697_36010	COG1376	ErfK ybiS ycfS ynhG family protein
IM697_36025	COG2197	response regulator
IM697_36030	COG4585	Histidine kinase
IM697_36040	COG1131	(ABC) transporter
IM697_36050	COG1132	(ABC) transporter
IM697_36055	COG1132	(ABC) transporter
IM697_36060	COG1132	(ABC) transporter
IM697_36085	COG0058	SHG alpha-glucan phosphorylase activity
IM697_36095	COG0366	Alpha amylase catalytic
IM697_36100	COG0366	Alpha amylase catalytic
IM697_36110	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IM697_36120	COG3118	belongs to the thioredoxin family
IM697_36120	COG0492	ferredoxin-NADP+ reductase activity
IM697_36130	COG1522	sequence-specific DNA binding
IM697_36140	COG0667	Aldo Keto reductase
IM697_36145	COG1301	dicarboxylic acid transport
IM697_36150	COG3290	protein histidine kinase activity
IM697_36155	COG4565	transcriptional regulatory protein
IM697_36165	COG1653	transport
IM697_36170	COG1175	transmembrane transport
IM697_36175	COG0395	ABC-type sugar transport system, permease component
IM697_36190	COG0205	6-phosphofructokinase activity
IM697_36195	COG0280	phosphate acetyltransferase
IM697_36195	COG0857	belongs to the CobB CobQ family
IM697_36200	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IM697_36260	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IM697_36260	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IM697_36275	COG2329	Antibiotic biosynthesis monooxygenase
IM697_36280	COG2124	cytochrome p450
IM697_36290	COG2159	amidohydrolase
IM697_36360	COG2205	protein histidine kinase activity
IM697_36365	COG0745	RESPONSE REGULATOR receiver
IM697_36385	COG0183	Belongs to the thiolase family
IM697_36390	COG0346	lactoylglutathione lyase activity
IM697_36405	COG1131	(ABC) transporter
IM697_36430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_36440	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
IM697_36455	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM697_36475	COG4585	Histidine kinase
IM697_36480	COG2197	response regulator
IM697_36495	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IM697_36500	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IM697_36505	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IM697_36510	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IM697_36515	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IM697_36520	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IM697_36525	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IM697_36545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IM697_36550	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IM697_36555	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IM697_36565	COG2890	protein-(glutamine-N5) methyltransferase activity
IM697_36570	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IM697_36575	COG0254	rRNA binding
IM697_36590	COG0083	homoserine kinase activity
IM697_36595	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IM697_36600	COG0460	homoserine dehydrogenase
IM697_36605	COG0019	diaminopimelate decarboxylase activity
IM697_36610	COG0018	arginyl-trna synthetase
IM697_36610	COG0018	arginyl-trna synthetase
IM697_36630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_36650	COG0431	NADPH-dependent FMN reductase
IM697_36655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_36660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_36665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM697_36670	COG1126	abc transporter atp-binding protein
IM697_36675	COG0765	amino acid transport
IM697_36680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM697_36690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_36695	COG0765	amino acid transport
IM697_36700	COG0745	RESPONSE REGULATOR receiver
IM697_36720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IM697_36725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_36730	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IM697_36755	COG1116	anion transmembrane transporter activity
IM697_36755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IM697_36760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IM697_36815	COG0514	ATP-dependent DNA helicase (RecQ)
IM697_36905	COG3251	PFAM MbtH domain protein
IM697_36910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM697_36945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM697_36950	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IM697_36955	COG1793	dna ligase
IM697_36955	COG3285	dna ligase
IM697_36975	COG2205	protein histidine kinase activity
IM697_36985	COG0772	Belongs to the SEDS family
IM697_36990	COG0768	penicillin binding
IM697_37020	COG0791	NLP P60 protein
IM697_37065	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IM697_37080	COG0745	RESPONSE REGULATOR receiver
IM697_37085	COG2205	protein histidine kinase activity
IM697_37090	COG0567	Dehydrogenase, E1 component
IM697_37090	COG0508	dehydrogenase complex catalyzes the overall conversion of
IM697_37100	COG3903	Transcriptional regulator
IM697_37100	COG3629	intracellular signal transduction
IM697_37140	COG0604	alcohol dehydrogenase
IM697_37145	COG0281	malic enzyme
IM697_37160	COG1126	abc transporter atp-binding protein
IM697_37185	COG0582	viral genome integration into host DNA
IM697_37250	COG1131	(ABC) transporter
IM697_37345	COG0142	geranyltranstransferase activity
IM697_37350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IM697_37390	COG1597	lipid kinase activity
IM697_37405	COG1309	transcriptional regulator
IM697_37410	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_37415	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IM697_37420	COG0363	glucosamine-6-phosphate deaminase activity
IM697_37425	COG1472	Belongs to the glycosyl hydrolase 3 family
IM697_37430	COG0395	ABC-type sugar transport system, permease component
IM697_37435	COG1175	transmembrane transport
IM697_37440	COG2182	Extracellular solute-binding protein
IM697_37445	COG2188	Transcriptional regulator
IM697_37450	COG1966	Carbon starvation protein
IM697_37485	COG2124	cytochrome p450
IM697_37495	COG0242	peptide deformylase activity
IM697_37510	COG2199	diguanylate cyclase activity
IM697_37510	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IM697_37515	COG5662	AntiSigma factor
IM697_37520	COG1595	DNA-templated transcription, initiation
IM697_37530	COG2135	peptidase activity
IM697_37550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM697_37555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM697_37560	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IM697_37585	COG2197	response regulator
IM697_37595	COG0604	alcohol dehydrogenase
IM697_37595	COG3321	synthase
IM697_37605	COG0318	PFAM AMP-dependent synthetase and ligase
IM697_37625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IM697_37630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IM697_37635	COG2130	NADP-dependent
IM697_37640	COG1819	glycosyl
IM697_37670	COG0596	Alpha beta hydrolase
IM697_37680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IM697_37685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM697_37695	COG0596	Alpha beta hydrolase
IM697_37705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IM697_37740	COG1960	acyl-CoA dehydrogenase activity
IM697_37775	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IM697_37795	COG0483	inositol monophosphate 1-phosphatase activity
IM697_37840	COG1615	UPF0182 protein
IM697_37850	COG3480	Lon protease (S16) C-terminal proteolytic domain
IM697_37900	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IM697_37935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM697_37940	COG0210	DNA helicase
IM697_37965	COG0596	Alpha beta hydrolase
IM697_38040	COG1432	Conserved Protein
IM697_38050	COG2095	MarC family integral membrane protein
IM697_38065	COG2814	Major facilitator Superfamily
IM697_38075	COG0598	Magnesium transport protein CorA
IM697_38110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IM697_38115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM697_38125	COG1595	DNA-templated transcription, initiation
IM697_38145	COG1024	Enoyl-CoA hydratase
IM697_38150	COG0519	Catalyzes the synthesis of GMP from XMP
IM697_38160	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IM697_38165	COG1611	Belongs to the LOG family
IM697_38170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM697_38205	COG2197	response regulator
IM697_38210	COG4585	Histidine kinase
IM697_38220	COG1131	(ABC) transporter
IM697_38235	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IM697_38250	COG4608	Belongs to the ABC transporter superfamily
IM697_38255	COG0444	Belongs to the ABC transporter superfamily
IM697_38260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM697_38265	COG0601	transmembrane transport
IM697_38275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM697_38280	COG0747	negative chemotaxis
IM697_38285	COG0601	transmembrane transport
IM697_38290	COG0444	Belongs to the ABC transporter superfamily
IM697_38295	COG4608	Belongs to the ABC transporter superfamily
IM697_38300	COG2197	response regulator
IM697_38305	COG4585	Histidine kinase
IM697_38310	COG2409	Drug exporters of the RND superfamily
IM697_38320	COG0346	lactoylglutathione lyase activity
IM697_38330	COG4608	Belongs to the ABC transporter superfamily
IM697_38335	COG0444	Belongs to the ABC transporter superfamily
IM697_38340	COG0601	transmembrane transport
IM697_38345	COG0747	negative chemotaxis
IM697_38350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM697_38355	COG1217	gtp-binding protein TYPA
IM697_38375	COG1053	succinate dehydrogenase
IM697_38425	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_38430	COG0583	DNA-binding transcription factor activity
IM697_38480	COG3119	arylsulfatase activity
IM697_38485	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IM697_38530	COG0012	GTP binding
IM697_38545	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IM697_38550	COG1570	exodeoxyribonuclease VII activity
IM697_38555	COG1722	exodeoxyribonuclease VII activity
IM697_38560	COG0778	Nitroreductase
IM697_38585	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IM697_38585	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IM697_38590	COG0114	fumarate hydratase activity
IM697_38605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM697_38625	COG1136	(ABC) transporter
IM697_38640	COG0450	alkyl hydroperoxide reductase
IM697_38645	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IM697_38660	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IM697_38665	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IM697_38730	COG2197	response regulator
IM697_38765	COG2894	cell division
IM697_38840	COG1595	DNA-templated transcription, initiation
IM697_38885	COG2610	gluconate transmembrane transporter activity
IM697_38890	COG0251	oxidation-reduction process
IM697_38895	COG1414	Transcriptional regulator
IM697_38910	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IM697_38930	COG0436	Aminotransferase
IM697_38960	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
IM697_38970	COG0477	Major facilitator Superfamily
IM697_38975	COG1309	transcriptional regulator
IM697_39005	COG1331	Highly conserved protein containing a thioredoxin domain
IM697_39020	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IM697_39030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IM697_39045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IM697_39050	COG2255	four-way junction helicase activity
IM697_39055	COG1595	DNA-templated transcription, initiation
IM697_39075	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IM697_39090	COG1064	alcohol dehydrogenase
IM697_39100	COG1136	(ABC) transporter
IM697_39130	COG2986	histidine ammonia-lyase
IM697_39140	COG1024	Enoyl-CoA hydratase
IM697_39150	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
IM697_39160	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IM697_39180	COG0424	maF-like protein
IM697_39190	COG4770	biotin carboxylase activity
IM697_39225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IM697_39240	COG1012	belongs to the aldehyde dehydrogenase family
IM697_39260	COG0477	Major facilitator Superfamily
IM697_39270	COG1595	DNA-templated transcription, initiation
IM697_39275	COG0745	RESPONSE REGULATOR receiver
IM697_39280	COG2205	protein histidine kinase activity
IM697_39305	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IM697_39320	COG0583	DNA-binding transcription factor activity
IM697_39325	COG0583	DNA-binding transcription factor activity
IM697_39330	COG2814	Major facilitator Superfamily
IM697_39365	COG1079	Belongs to the binding-protein-dependent transport system permease family
IM697_39375	COG3845	ABC transporter
IM697_39380	COG1744	ABC transporter substrate-binding protein PnrA-like
IM697_39385	COG1744	ABC transporter substrate-binding protein PnrA-like
IM697_39390	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
IM697_39390	COG1473	amidohydrolase
IM697_39405	COG2226	methyltransferase
IM697_39420	COG2089	acid synthase
IM697_39435	COG1216	Glycosyl transferase, family 2
IM697_39455	COG1216	Glycosyl transferase, family 2
IM697_39475	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IM697_39475	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IM697_39490	COG1595	DNA-templated transcription, initiation
IM697_39580	COG3525	Glycosyl hydrolase, family 20, catalytic domain
IM697_39590	COG2009	succinate dehydrogenase
IM697_39600	COG1053	succinate dehydrogenase
IM697_39645	COG2409	Drug exporters of the RND superfamily
IM697_39650	COG0745	RESPONSE REGULATOR receiver
IM697_39655	COG2205	protein histidine kinase activity
IM697_39670	COG1408	metallophosphoesterase
IM697_39680	COG1686	Belongs to the peptidase S11 family
IM697_39685	COG1295	ribonuclease BN
IM697_39705	COG0180	Tryptophanyl-tRNA synthetase
IM697_39710	COG1595	DNA-templated transcription, initiation
IM697_39730	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IM697_39735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IM697_39750	COG0512	Glutamine amidotransferase of anthranilate synthase
IM697_39750	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IM697_39755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IM697_39775	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IM697_39780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM697_39795	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IM697_39800	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IM697_39815	COG4176	ABC-type proline glycine betaine transport system permease component
IM697_39820	COG4175	Glycine betaine
IM697_39820	COG0517	IMP dehydrogenase activity
IM697_39830	COG1012	belongs to the aldehyde dehydrogenase family
IM697_39835	COG2318	DinB family
IM697_39915	COG0039	L-malate dehydrogenase activity
IM697_39935	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IM697_39950	COG0515	serine threonine protein kinase
IM697_39950	COG2815	serine threonine protein kinase
IM697_39960	COG0515	serine threonine protein kinase
IM697_39980	COG3409	Peptidoglycan-binding domain 1 protein
IM697_40010	COG2815	serine threonine protein kinase
IM697_40010	COG0515	serine threonine protein kinase
IM697_40020	COG0138	bifunctional purine biosynthesis protein purh
IM697_40050	COG0045	succinate-CoA ligase (ADP-forming) activity
IM697_40065	COG3552	Protein containing von Willebrand factor type A (VWA) domain
IM697_40070	COG2425	protein containing a von Willebrand factor type A (vWA) domain
IM697_40075	COG0714	Associated with various cellular activities
IM697_40090	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IM697_40090	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IM697_40125	COG0791	NLP P60 protein
IM697_40130	COG2197	response regulator
IM697_40175	COG0519	Catalyzes the synthesis of GMP from XMP
IM697_40175	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IM697_40210	COG1012	belongs to the aldehyde dehydrogenase family
IM697_40220	COG0515	serine threonine protein kinase
IM697_40225	COG0515	serine threonine protein kinase
IM697_40230	COG0515	serine threonine protein kinase
IM697_40230	COG2815	serine threonine protein kinase
IM697_40235	COG2815	serine threonine protein kinase
IM697_40235	COG0515	serine threonine protein kinase
IM697_40240	COG2815	serine threonine protein kinase
IM697_40240	COG0515	serine threonine protein kinase
IM697_40250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IM697_40260	COG0516	GMP reductase activity
IM697_40270	COG1595	DNA-templated transcription, initiation
IM697_40285	COG0583	DNA-binding transcription factor activity
IM697_40295	COG2132	Multicopper oxidase
IM697_40300	COG4221	oxidoreductase activity
IM697_40310	COG0459	protein refolding
IM697_40320	COG0726	polysaccharide deacetylase
IM697_40325	COG0726	polysaccharide deacetylase
IM697_40335	COG4941	Belongs to the sigma-70 factor family
IM697_40345	COG1316	TRANSCRIPTIONal
IM697_40350	COG1609	Transcriptional regulator
IM697_40355	COG1472	Belongs to the glycosyl hydrolase 3 family
IM697_40365	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IM697_40390	COG0802	atpase or kinase
IM697_40400	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IM697_40410	COG0736	holo-[acyl-carrier-protein] synthase activity
IM697_40445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IM697_40470	COG1072	(Pantothenic acid kinase))
IM697_40495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM697_40495	COG3321	synthase
IM697_40505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IM697_40510	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IM697_40515	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IM697_40520	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IM697_40540	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IM697_40550	COG2843	Capsule synthesis protein
IM697_40560	COG0101	tRNA pseudouridine synthase activity
IM697_40565	COG0203	ribosomal protein L17
IM697_40570	COG0202	RNA polymerase activity
IM697_40575	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IM697_40580	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IM697_40585	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IM697_40590	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IM697_40600	COG0563	adenylate kinase activity
IM697_40610	COG0200	Binds to the 23S rRNA
IM697_40615	COG1841	ribosomal large subunit assembly
IM697_40620	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IM697_40625	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IM697_40630	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IM697_40635	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IM697_40640	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IM697_40645	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IM697_40650	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IM697_40655	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IM697_40660	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IM697_40665	COG0255	Belongs to the universal ribosomal protein uL29 family
IM697_40670	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IM697_40675	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IM697_40680	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IM697_40685	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IM697_40690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IM697_40695	COG0089	rRNA binding
IM697_40700	COG0088	Forms part of the polypeptide exit tunnel
IM697_40705	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IM697_40710	COG0051	transcription antitermination factor activity, RNA binding
IM697_40715	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IM697_40745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IM697_40755	COG0110	maltose O-acetyltransferase activity
IM697_40765	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IM697_40775	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IM697_40780	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IM697_40785	COG0049	tRNA binding
IM697_40790	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IM697_40800	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IM697_40805	COG0085	RNA polymerase activity
IM697_40810	COG0222	ribosome binding
IM697_40815	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IM697_40825	COG0081	regulation of translation
IM697_40840	COG0250	Participates in transcription elongation, termination and antitermination
IM697_40855	COG0436	Aminotransferase
IM697_40860	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IM697_40865	COG1309	transcriptional regulator
IM697_40875	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IM697_40885	COG0477	Major facilitator Superfamily
IM697_40900	COG2030	dehydratase
IM697_40905	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IM697_40920	COG0402	S-adenosylhomocysteine deaminase activity
IM697_40925	COG0702	epimerase
IM697_40945	COG1666	GTP binding
IM697_40950	COG2261	transglycosylase associated protein
IM697_40965	COG3304	Inner membrane component domain
IM697_40970	COG0501	Belongs to the peptidase M48B family
IM697_40975	COG1007	ATP synthesis coupled electron transport
IM697_40985	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IM697_40990	COG0713	ATP synthesis coupled electron transport
IM697_40995	COG0839	Belongs to the complex I subunit 6 family
IM697_41000	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM697_41005	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IM697_41010	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM697_41015	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM697_41020	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM697_41040	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IM697_41040	COG0674	pyruvate-flavodoxin oxidoreductase activity
IM697_41045	COG1013	pyruvate-flavodoxin oxidoreductase activity
IM697_41055	COG1733	regulation of RNA biosynthetic process
IM697_41060	COG0702	epimerase
IM697_41075	COG4935	Belongs to the peptidase S8 family
IM697_41075	COG2234	aminopeptidase activity
IM697_41090	COG0154	amidase activity
IM697_41105	COG1131	(ABC) transporter
IM697_41120	COG0142	geranyltranstransferase activity
IM697_41135	COG0561	phosphatase activity
IM697_41150	COG0514	ATP-dependent DNA helicase (RecQ)
IM697_41155	COG1007	ATP synthesis coupled electron transport
IM697_41165	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IM697_41170	COG0713	ATP synthesis coupled electron transport
IM697_41175	COG0839	Belongs to the complex I subunit 6 family
IM697_41180	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM697_41185	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IM697_41190	COG1034	ATP synthesis coupled electron transport
IM697_41195	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IM697_41205	COG0649	NAD binding
IM697_41210	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM697_41215	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM697_41235	COG0242	peptide deformylase activity
IM697_41260	COG2226	methyltransferase
IM697_41290	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
IM697_41305	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
IM697_41310	COG1278	Cold shock
IM697_41315	COG1396	sequence-specific DNA binding
IM697_41345	COG1053	succinate dehydrogenase
IM697_41355	COG4213	ABC transporter substrate-binding protein
IM697_41370	COG0183	Belongs to the thiolase family
IM697_41385	COG1309	transcriptional regulator
IM697_41410	COG1573	uracil-dna glycosylase
IM697_41415	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
IM697_41425	COG0163	prenyltransferase activity
IM697_41445	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IM697_41485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IM697_41490	COG1333	cytochrome c biogenesis protein
IM697_41495	COG0785	Cytochrome C biogenesis protein
IM697_41500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IM697_41510	COG0406	alpha-ribazole phosphatase activity
IM697_41515	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IM697_41525	COG0582	viral genome integration into host DNA
IM697_41595	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IM697_41620	COG0697	spore germination
IM697_41625	COG0583	DNA-binding transcription factor activity
IM697_41640	COG2205	protein histidine kinase activity
IM697_41655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM697_41675	COG1742	UPF0060 membrane protein
IM697_41690	COG1690	Belongs to the RtcB family
IM697_41710	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
IM697_41715	COG0018	arginyl-trna synthetase
IM697_41740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM697_41750	COG0113	porphobilinogen synthase activity
IM697_41760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IM697_41760	COG1648	precorrin-2 dehydrogenase activity
IM697_41765	COG0181	hydroxymethylbilane synthase activity
IM697_41770	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IM697_41775	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IM697_41825	COG0123	including yeast histone deacetylase and acetoin utilization protein
IM697_41840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM697_41860	COG0180	Tryptophanyl-tRNA synthetase
IM697_41865	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IM697_41875	COG0842	Transport permease protein
IM697_41875	COG1129	ABC transporter
IM697_41890	COG4991	sh3 domain protein
IM697_41895	COG4991	sh3 domain protein
IM697_41905	COG0129	dihydroxy-acid dehydratase activity
IM697_41910	COG1309	transcriptional regulator
IM697_41915	COG1082	Xylose isomerase domain protein TIM barrel
IM697_41920	COG0248	Ppx GppA phosphatase
IM697_41940	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IM697_41960	COG1595	DNA-templated transcription, initiation
IM697_41970	COG0745	RESPONSE REGULATOR receiver
IM697_41975	COG2205	protein histidine kinase activity
IM697_42000	COG0739	heme binding
IM697_42040	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IM697_42060	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IM697_42070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IM697_42075	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IM697_42100	COG1660	Displays ATPase and GTPase activities
IM697_42120	COG0649	NAD binding
IM697_42160	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IM697_42175	COG0302	gtp cyclohydrolase
IM697_42190	COG0037	tRNA processing
IM697_42200	COG2027	D-alanyl-D-alanine carboxypeptidase
IM697_42205	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IM697_42215	COG0586	Pfam SNARE associated Golgi protein
IM697_42220	COG0393	Putative heavy-metal-binding
IM697_42225	COG0789	Transcriptional regulator
IM697_42235	COG0076	glutamate decarboxylase activity
IM697_42255	COG2318	DinB family
IM697_42270	COG1733	regulation of RNA biosynthetic process
IM697_42275	COG1012	belongs to the aldehyde dehydrogenase family
IM697_42295	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IM697_42305	COG0254	rRNA binding
IM697_42310	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IM697_42315	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IM697_42320	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IM697_42345	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IM697_42345	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IM697_42380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM697_42415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IM697_42440	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IM697_42490	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IM697_42520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM697_42550	COG0367	asparagine synthase
IM697_42595	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IM697_42615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IM697_42620	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IM697_42630	COG1280	lysine exporter protein (LysE YggA)
IM697_42640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IM697_42645	COG2954	triphosphatase activity
IM697_42655	COG0477	Major facilitator Superfamily
IM697_42685	COG3251	PFAM MbtH domain protein
IM697_42690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IM697_42710	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IM697_42715	COG1754	DNA topoisomerase type I activity
IM697_42715	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IM697_42735	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IM697_42740	COG2172	sigma factor antagonist activity
IM697_42745	COG1366	Belongs to the anti-sigma-factor antagonist family
IM697_42810	COG0659	secondary active sulfate transmembrane transporter activity
IM697_42815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IM697_42820	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IM697_42830	COG2267	carboxylic ester hydrolase activity
IM697_42860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM697_42885	COG0003	Pfam Anion-transporting ATPase
IM697_42895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM697_42905	COG1408	metallophosphoesterase
IM697_42935	COG1609	Transcriptional regulator
IM697_43015	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IM697_43020	COG1181	Belongs to the D-alanine--D-alanine ligase family
IM697_43030	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IM697_43045	COG0402	S-adenosylhomocysteine deaminase activity
IM697_43055	COG0667	Aldo Keto reductase
IM697_43070	COG2197	response regulator
IM697_43075	COG4585	Histidine kinase
IM697_43110	COG4585	Histidine kinase
IM697_43115	COG2197	response regulator
IM697_43120	COG2409	Drug exporters of the RND superfamily
IM697_43125	COG1408	metallophosphoesterase
IM697_43140	COG1063	alcohol dehydrogenase
IM697_43150	COG1309	transcriptional regulator
IM697_43165	COG3328	transposase activity
IM697_43175	COG2318	DinB family
IM697_43180	COG2226	methyltransferase
IM697_43240	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IM697_43280	COG1595	DNA-templated transcription, initiation
IM697_43285	COG2319	Wd-40 repeat
IM697_43285	COG4249	Peptidase C14 caspase catalytic subunit p20
IM697_43290	COG2188	Transcriptional regulator
IM697_43310	COG0701	Predicted permease
IM697_43330	COG1295	ribonuclease BN
IM697_43395	COG1595	DNA-templated transcription, initiation
IM697_43425	COG2205	protein histidine kinase activity
IM697_43455	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IM697_43460	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IM697_43485	COG0693	protein deglycase activity
IM697_43495	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IM697_43505	COG0463	Glycosyl transferase, family 2
IM697_43555	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IM697_43570	COG1131	(ABC) transporter
IM697_43575	COG3559	Exporter of polyketide antibiotics
IM697_43580	COG2124	cytochrome p450
IM697_43605	COG2197	response regulator
IM697_43610	COG4585	Histidine kinase
IM697_43615	COG2197	response regulator
IM697_43620	COG4585	Histidine kinase
IM697_43645	COG3844	kynureninase activity
IM697_43660	COG0477	Major facilitator Superfamily
IM697_43665	COG0191	fructose-bisphosphate aldolase activity
IM697_43670	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IM697_43690	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IM697_43705	COG0542	response to heat
IM697_43745	COG1305	Transglutaminase-like
IM697_43750	COG4213	ABC transporter substrate-binding protein
IM697_43765	COG0789	Transcriptional regulator
IM697_43770	COG0484	heat shock protein binding
IM697_43775	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IM697_43780	COG0443	Heat shock 70 kDa protein
IM697_43785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IM697_43790	COG0247	lactate metabolic process
IM697_43790	COG2181	nitrate reductase activity
IM697_43795	COG2826	transposase and inactivated derivatives, IS30 family
IM697_43875	COG0717	Belongs to the dCTP deaminase family
IM697_43885	COG1309	transcriptional regulator
IM697_43900	COG2124	cytochrome p450
IM697_43900	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IM697_43905	COG1231	oxidoreductase activity
IM697_43935	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
IM697_43995	COG0667	Aldo Keto reductase
IM697_44000	COG2080	2 iron, 2 sulfur cluster binding
IM697_44005	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IM697_44010	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IM697_44015	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IM697_44015	COG3608	succinylglutamate desuccinylase aspartoacylase
IM697_44020	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IM697_44055	COG1278	Cold shock
IM697_44060	COG0513	Belongs to the DEAD box helicase family
IM697_44080	COG4585	Histidine kinase
IM697_44085	COG2197	response regulator
IM697_44100	COG1132	(ABC) transporter
IM697_44110	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IM697_44130	COG4249	Peptidase C14 caspase catalytic subunit p20
IM697_44130	COG2319	Wd-40 repeat
IM697_44140	COG3250	beta-galactosidase activity
IM697_44150	COG1028	Short-chain dehydrogenase reductase Sdr
IM697_44190	COG3835	regulator
IM697_44205	COG2188	Transcriptional regulator
IM697_44210	COG1115	amino acid carrier protein
IM697_44220	COG0583	DNA-binding transcription factor activity
IM697_44235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM697_44240	COG3938	Belongs to the proline racemase family
IM697_44265	COG2226	methyltransferase
IM697_44300	COG4213	ABC transporter substrate-binding protein
IM697_44315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IM697_44325	COG2197	response regulator
IM697_44330	COG4585	Histidine kinase
IM697_44360	COG2205	protein histidine kinase activity
IM697_44365	COG0745	RESPONSE REGULATOR receiver
IM697_44380	COG1376	ErfK ybiS ycfS ynhG family protein
IM697_44385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM697_44405	COG0569	domain protein