locus-tag	class	description
HUT09_00130	COG4977	sequence-specific DNA binding
HUT09_00235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_00240	COG0366	Alpha amylase catalytic
HUT09_00260	COG0456	acetyltransferase
HUT09_00285	COG0019	diaminopimelate decarboxylase activity
HUT09_00400	COG0714	Associated with various cellular activities
HUT09_00460	COG1309	transcriptional regulator
HUT09_00465	COG2409	Drug exporters of the RND superfamily
HUT09_00510	COG2205	protein histidine kinase activity
HUT09_00515	COG0745	RESPONSE REGULATOR receiver
HUT09_00590	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HUT09_00595	COG4106	trans-aconitate 2-methyltransferase activity
HUT09_00605	COG1846	Transcriptional regulator
HUT09_00610	COG1764	response to oxidative stress
HUT09_00625	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_00655	COG0277	FAD linked oxidase domain protein
HUT09_00665	COG1902	pentaerythritol trinitrate reductase activity
HUT09_00670	COG0640	Transcriptional regulator
HUT09_00675	COG1064	alcohol dehydrogenase
HUT09_00720	COG0642	Histidine kinase
HUT09_00740	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
HUT09_00750	COG0366	Alpha amylase catalytic
HUT09_00755	COG0395	ABC-type sugar transport system, permease component
HUT09_00760	COG1175	transmembrane transport
HUT09_00765	COG1653	transport
HUT09_00820	COG1349	DNA-binding transcription factor activity
HUT09_00825	COG1105	Belongs to the carbohydrate kinase PfkB family
HUT09_00835	COG0681	Belongs to the peptidase S26 family
HUT09_00855	COG0596	Alpha beta hydrolase
HUT09_00900	COG0254	rRNA binding
HUT09_00905	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUT09_00965	COG1024	Enoyl-CoA hydratase
HUT09_00990	COG0765	amino acid transport
HUT09_01000	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_01015	COG2072	flavoprotein involved in K transport
HUT09_01030	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_01035	COG2070	2-Nitropropane dioxygenase
HUT09_01040	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT09_01055	COG0515	serine threonine protein kinase
HUT09_01070	COG4221	oxidoreductase activity
HUT09_01080	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT09_01085	COG0346	lactoylglutathione lyase activity
HUT09_01100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT09_01110	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HUT09_01110	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HUT09_01110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT09_01110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT09_01110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT09_01110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT09_01110	COG3321	synthase
HUT09_01110	COG3321	synthase
HUT09_01115	COG3321	synthase
HUT09_01115	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_01115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT09_01115	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_01115	COG0300	oxidoreductase activity
HUT09_01120	COG1960	acyl-CoA dehydrogenase activity
HUT09_01125	COG2813	Specifically methylates the guanine in position
HUT09_01140	COG2356	endonuclease I
HUT09_01145	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HUT09_01145	COG2066	Belongs to the glutaminase family
HUT09_01160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUT09_01165	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
HUT09_01180	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT09_01185	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUT09_01190	COG2080	2 iron, 2 sulfur cluster binding
HUT09_01250	COG2365	Tyrosine phosphatase family
HUT09_01275	COG1120	ATPase activity
HUT09_01280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUT09_01290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT09_01300	COG0477	Major facilitator Superfamily
HUT09_01305	COG2382	esterase
HUT09_01310	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_01315	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_01320	COG1169	isochorismate synthase
HUT09_01325	COG1021	2,3-dihydroxybenzoate-AMP ligase
HUT09_01330	COG3433	isochorismatase activity
HUT09_01330	COG1535	isochorismatase
HUT09_01335	COG1535	isochorismatase
HUT09_01335	COG3433	isochorismatase activity
HUT09_01340	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HUT09_01450	COG3845	ABC transporter
HUT09_01470	COG1470	cell adhesion involved in biofilm formation
HUT09_01490	COG1063	alcohol dehydrogenase
HUT09_01495	COG0395	ABC-type sugar transport system, permease component
HUT09_01510	COG1349	DNA-binding transcription factor activity
HUT09_01540	COG0589	response to stress
HUT09_01550	COG2382	esterase
HUT09_01555	COG1132	(ABC) transporter
HUT09_01565	COG1132	(ABC) transporter
HUT09_01570	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HUT09_01575	COG1120	ATPase activity
HUT09_01580	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_01585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_01590	COG3486	L-lysine 6-monooxygenase (NADPH) activity
HUT09_01610	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUT09_01640	COG0640	Transcriptional regulator
HUT09_01675	COG1132	(ABC) transporter
HUT09_01700	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT09_01720	COG0504	CTP synthase activity
HUT09_01725	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HUT09_01730	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUT09_01740	COG0640	Transcriptional regulator
HUT09_01765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUT09_01770	COG0573	inorganic phosphate transmembrane transporter activity
HUT09_01775	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HUT09_01795	COG0640	Transcriptional regulator
HUT09_01810	COG2072	flavoprotein involved in K transport
HUT09_01815	COG0798	PFAM Bile acid sodium symporter
HUT09_01825	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT09_01830	COG2376	Dihydroxyacetone kinase
HUT09_01835	COG1461	Dihydroxyacetone kinase
HUT09_01850	COG0488	(ABC) transporter
HUT09_01880	COG1191	sigma factor activity
HUT09_01890	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUT09_01895	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUT09_01910	COG1120	ATPase activity
HUT09_01915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_01940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT09_01990	COG1959	2 iron, 2 sulfur cluster binding
HUT09_01990	COG1295	ribonuclease BN
HUT09_02025	COG1120	ATPase activity
HUT09_02030	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_02035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_02055	COG1309	transcriptional regulator
HUT09_02080	COG1874	Beta-galactosidase
HUT09_02080	COG0366	Alpha amylase catalytic
HUT09_02095	COG1609	Transcriptional regulator
HUT09_02100	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT09_02110	COG1129	ABC transporter
HUT09_02115	COG1879	ABC-type sugar transport system periplasmic component
HUT09_02145	COG1131	(ABC) transporter
HUT09_02145	COG0842	Transport permease protein
HUT09_02145	COG1716	ATPase activity
HUT09_02195	COG0328	RNA-DNA hybrid ribonuclease activity
HUT09_02200	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_02210	COG1132	(ABC) transporter
HUT09_02220	COG2264	protein methyltransferase activity
HUT09_02230	COG4753	response regulator
HUT09_02230	COG2207	Transcriptional regulator
HUT09_02235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_02240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_02245	COG1120	ATPase activity
HUT09_02285	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT09_02290	COG0477	Major facilitator Superfamily
HUT09_02340	COG0464	growth
HUT09_02350	COG1349	DNA-binding transcription factor activity
HUT09_02365	COG0702	epimerase
HUT09_02375	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUT09_02390	COG1940	carbohydrate kinase activity
HUT09_02395	COG2223	nitrite transmembrane transporter activity
HUT09_02425	COG0445	tRNA wobble uridine modification
HUT09_02430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT09_02440	COG1660	Displays ATPase and GTPase activities
HUT09_02465	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HUT09_02470	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HUT09_02475	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HUT09_02495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT09_02500	COG2376	Dihydroxyacetone kinase
HUT09_02505	COG2376	Dihydroxyacetone kinase
HUT09_02510	COG0531	amino acid
HUT09_02520	COG1940	carbohydrate kinase activity
HUT09_02550	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HUT09_02595	COG0584	glycerophosphoryl diester phosphodiesterase
HUT09_02600	COG0456	acetyltransferase
HUT09_02615	COG0671	phosphoesterase, PA-phosphatase related
HUT09_02640	COG2226	methyltransferase
HUT09_02665	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HUT09_02680	COG2706	6-phosphogluconolactonase activity
HUT09_02695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT09_02700	COG2815	serine threonine protein kinase
HUT09_02700	COG0515	serine threonine protein kinase
HUT09_02705	COG0667	Aldo Keto reductase
HUT09_02710	COG3469	chitinase activity
HUT09_02745	COG1253	flavin adenine dinucleotide binding
HUT09_02780	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HUT09_02785	COG0531	amino acid
HUT09_02790	COG2186	Transcriptional regulator
HUT09_02795	COG0174	glutamine synthetase
HUT09_02800	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_02835	COG4981	capsule polysaccharide biosynthetic process
HUT09_02855	COG2835	tetraacyldisaccharide 4'-kinase activity
HUT09_02870	COG1802	Transcriptional regulator
HUT09_02880	COG0402	S-adenosylhomocysteine deaminase activity
HUT09_02895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_02900	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_02905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUT09_02910	COG1132	(ABC) transporter
HUT09_02945	COG1357	PFAM Pentapeptide repeats (8 copies)
HUT09_02980	COG0546	phosphoglycolate phosphatase activity
HUT09_03020	COG1191	sigma factor activity
HUT09_03045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT09_03060	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HUT09_03065	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_03070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_03080	COG4592	Periplasmic binding protein
HUT09_03115	COG2226	methyltransferase
HUT09_03140	COG2957	Belongs to the agmatine deiminase family
HUT09_03150	COG0444	Belongs to the ABC transporter superfamily
HUT09_03155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT09_03165	COG0747	negative chemotaxis
HUT09_03170	COG2957	Belongs to the agmatine deiminase family
HUT09_03175	COG0804	urea catabolic process
HUT09_03180	COG0831	urea catabolic process
HUT09_03180	COG0832	Belongs to the urease beta subunit family
HUT09_03190	COG0515	serine threonine protein kinase
HUT09_03195	COG1309	transcriptional regulator
HUT09_03200	COG2957	Belongs to the agmatine deiminase family
HUT09_03225	COG2197	response regulator
HUT09_03230	COG0432	Pfam Uncharacterised protein family UPF0047
HUT09_03235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT09_03240	COG1116	anion transmembrane transporter activity
HUT09_03250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_03255	COG2072	flavoprotein involved in K transport
HUT09_03270	COG1132	(ABC) transporter
HUT09_03275	COG1846	Transcriptional regulator
HUT09_03280	COG0277	FAD linked oxidase domain protein
HUT09_03285	COG0673	inositol 2-dehydrogenase activity
HUT09_03290	COG1132	(ABC) transporter
HUT09_03295	COG1132	(ABC) transporter
HUT09_03320	COG1252	NADH dehydrogenase
HUT09_03325	COG1793	dna ligase
HUT09_03340	COG1946	Acyl-CoA thioesterase
HUT09_03350	COG3387	PFAM Glycoside hydrolase 15-related
HUT09_03375	COG0386	Belongs to the glutathione peroxidase family
HUT09_03380	COG1960	acyl-CoA dehydrogenase activity
HUT09_03390	COG0242	peptide deformylase activity
HUT09_03400	COG3442	glutamine amidotransferase
HUT09_03405	COG0205	6-phosphofructokinase activity
HUT09_03420	COG0204	Acyl-transferase
HUT09_03435	COG0829	nickel cation binding
HUT09_03440	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HUT09_03450	COG0804	urea catabolic process
HUT09_03455	COG0832	Belongs to the urease beta subunit family
HUT09_03460	COG0831	urea catabolic process
HUT09_03465	COG1309	transcriptional regulator
HUT09_03485	COG0740	serine-type endopeptidase activity
HUT09_03495	COG0791	NLP P60 protein
HUT09_03500	COG1280	lysine exporter protein (LysE YggA)
HUT09_03505	COG0583	DNA-binding transcription factor activity
HUT09_03530	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HUT09_03535	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT09_03540	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HUT09_03545	COG2226	methyltransferase
HUT09_03815	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUT09_03830	COG1940	carbohydrate kinase activity
HUT09_03835	COG2188	Transcriptional regulator
HUT09_03840	COG1595	DNA-templated transcription, initiation
HUT09_03855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT09_03880	COG0626	cystathionine gamma-synthase activity
HUT09_03905	COG1522	sequence-specific DNA binding
HUT09_03910	COG0419	ATPase involved in DNA repair
HUT09_03915	COG0420	3'-5' exonuclease activity
HUT09_03920	COG1739	Uncharacterized protein family UPF0029
HUT09_03925	COG1832	CoA-binding protein
HUT09_03970	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HUT09_03990	COG1968	undecaprenyl-diphosphatase activity
HUT09_04005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUT09_04055	COG2318	DinB family
HUT09_04070	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HUT09_04135	COG0697	spore germination
HUT09_04175	COG1695	Transcriptional regulator
HUT09_04250	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT09_04250	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT09_04260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUT09_04280	COG1716	ATPase activity
HUT09_04300	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUT09_04330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT09_04340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT09_04355	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HUT09_04385	COG2018	Roadblock/LC7 domain
HUT09_04450	COG2364	Membrane
HUT09_04460	COG2270	Major facilitator Superfamily
HUT09_04470	COG3030	protein affecting phage T7 exclusion by the F plasmid
HUT09_04475	COG1216	Glycosyl transferase, family 2
HUT09_04495	COG1960	acyl-CoA dehydrogenase activity
HUT09_04550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HUT09_04555	COG0140	phosphoribosyl-ATP diphosphatase activity
HUT09_04560	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HUT09_04565	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT09_04565	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT09_04570	COG3201	nicotinamide mononucleotide transporter
HUT09_04600	COG0738	Major facilitator superfamily
HUT09_04605	COG2233	PERMEase
HUT09_04625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT09_04635	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_04650	COG2390	Transcriptional regulator
HUT09_04655	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HUT09_04665	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUT09_04680	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HUT09_04690	COG1758	RNA polymerase activity
HUT09_04705	COG0284	orotidine-5'-phosphate decarboxylase activity
HUT09_04710	COG0167	dihydroorotate dehydrogenase activity
HUT09_04715	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUT09_04720	COG0505	Belongs to the CarA family
HUT09_04730	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT09_04735	COG0540	Belongs to the ATCase OTCase family
HUT09_04740	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HUT09_04750	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUT09_04755	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HUT09_04760	COG0006	proline dipeptidase activity
HUT09_04770	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HUT09_04775	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HUT09_04780	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HUT09_04785	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUT09_04795	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HUT09_04800	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUT09_04820	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HUT09_04840	COG0124	histidyl-tRNA synthetase
HUT09_04855	COG1196	nuclear chromosome segregation
HUT09_04860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUT09_04865	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HUT09_04870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT09_04875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT09_04885	COG2255	four-way junction helicase activity
HUT09_04890	COG0632	four-way junction helicase activity
HUT09_04895	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HUT09_04900	COG0217	transcriptional regulatory protein
HUT09_04905	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HUT09_04910	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HUT09_04920	COG0438	transferase activity, transferring glycosyl groups
HUT09_04925	COG1560	Kdo2-lipid A biosynthetic process
HUT09_04930	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HUT09_04955	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HUT09_04970	COG2176	DNA-directed DNA polymerase activity
HUT09_04970	COG5002	protein histidine kinase activity
HUT09_05030	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUT09_05085	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUT09_05085	COG1648	precorrin-2 dehydrogenase activity
HUT09_05090	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HUT09_05105	COG1464	Belongs to the NlpA lipoprotein family
HUT09_05110	COG2011	ABC-type metal ion transport system permease component
HUT09_05150	COG0477	Major facilitator Superfamily
HUT09_05160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT09_05165	COG3973	AAA domain
HUT09_05175	COG0165	Argininosuccinate lyase
HUT09_05180	COG0137	argininosuccinate synthase activity
HUT09_05200	COG1438	arginine binding
HUT09_05205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT09_05210	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HUT09_05215	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HUT09_05220	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HUT09_05230	COG0385	Bile acid
HUT09_05280	COG0697	spore germination
HUT09_05290	COG1649	PFAM Uncharacterised BCR, COG1649
HUT09_05310	COG0072	phenylalanine-tRNA ligase activity
HUT09_05310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUT09_05315	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HUT09_05320	COG5002	protein histidine kinase activity
HUT09_05325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUT09_05330	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HUT09_05335	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HUT09_05340	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HUT09_05400	COG0517	IMP dehydrogenase activity
HUT09_05400	COG4175	Glycine betaine
HUT09_05405	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUT09_05450	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT09_05455	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT09_05495	COG0805	protein transport
HUT09_05500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT09_05520	COG2378	regulation of single-species biofilm formation
HUT09_05530	COG0545	Peptidyl-prolyl cis-trans isomerase
HUT09_05535	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT09_05545	COG1609	Transcriptional regulator
HUT09_05550	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT09_05555	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT09_05570	COG4122	O-methyltransferase activity
HUT09_05575	COG1222	aaa ATPase
HUT09_05595	COG1994	Peptidase M50
HUT09_05595	COG0517	IMP dehydrogenase activity
HUT09_05605	COG2197	response regulator
HUT09_05610	COG4166	transmembrane transport
HUT09_05620	COG0646	methionine synthase
HUT09_05620	COG1410	methionine synthase
HUT09_05625	COG1414	Transcriptional regulator
HUT09_05630	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUT09_05635	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT09_05640	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUT09_05645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_05660	COG0215	cysteine-tRNA ligase activity
HUT09_05680	COG0598	Magnesium transport protein CorA
HUT09_05690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_05695	COG0667	Aldo Keto reductase
HUT09_05725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT09_05735	COG0564	pseudouridine synthase activity
HUT09_05750	COG2186	Transcriptional regulator
HUT09_05755	COG3265	gluconokinase activity
HUT09_05780	COG3573	Dehydrogenase
HUT09_05785	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HUT09_05790	COG2149	membrane
HUT09_05805	COG4948	Mandelate Racemase Muconate Lactonizing
HUT09_05815	COG1960	acyl-CoA dehydrogenase activity
HUT09_05820	COG4935	Belongs to the peptidase S8 family
HUT09_05820	COG2234	aminopeptidase activity
HUT09_05830	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_05840	COG3876	Protein conserved in bacteria
HUT09_05915	COG1960	acyl-CoA dehydrogenase activity
HUT09_05925	COG0697	spore germination
HUT09_05930	COG2326	polyphosphate kinase activity
HUT09_05945	COG3842	ATPase activity
HUT09_05955	COG2851	Citrate transporter
HUT09_05960	COG0243	molybdopterin cofactor binding
HUT09_05965	COG1309	transcriptional regulator
HUT09_05970	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HUT09_05975	COG2188	Transcriptional regulator
HUT09_05985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT09_05995	COG2755	lipolytic protein G-D-S-L family
HUT09_06005	COG1725	Transcriptional regulator
HUT09_06020	COG2226	methyltransferase
HUT09_06040	COG4565	transcriptional regulatory protein
HUT09_06045	COG0456	acetyltransferase
HUT09_06075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUT09_06080	COG0587	DNA-directed DNA polymerase activity
HUT09_06120	COG0641	radical SAM
HUT09_06155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_06195	COG1799	cell septum assembly
HUT09_06200	COG1960	acyl-CoA dehydrogenase activity
HUT09_06205	COG0477	Major facilitator Superfamily
HUT09_06210	COG0671	phosphoesterase, PA-phosphatase related
HUT09_06225	COG0438	transferase activity, transferring glycosyl groups
HUT09_06240	COG1160	GTP binding
HUT09_06250	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HUT09_06290	COG3541	Predicted nucleotidyltransferase
HUT09_06300	COG0494	nUDIX hydrolase
HUT09_06315	COG1187	pseudouridine synthase activity
HUT09_06320	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HUT09_06325	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HUT09_06340	COG0686	Belongs to the AlaDH PNT family
HUT09_06355	COG0504	CTP synthase activity
HUT09_06360	COG3387	PFAM Glycoside hydrolase 15-related
HUT09_06380	COG3119	arylsulfatase activity
HUT09_06385	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUT09_06395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT09_06400	COG0601	transmembrane transport
HUT09_06435	COG0497	DNA recombination
HUT09_06440	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUT09_06460	COG1120	ATPase activity
HUT09_06465	COG0647	UMP catabolic process
HUT09_06495	COG2094	Belongs to the DNA glycosylase MPG family
HUT09_06505	COG1881	PFAM PEBP family protein
HUT09_06530	COG1119	ATPase activity
HUT09_06545	COG2197	response regulator
HUT09_06550	COG4585	Histidine kinase
HUT09_06560	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HUT09_06570	COG1716	ATPase activity
HUT09_06570	COG1131	(ABC) transporter
HUT09_06570	COG0842	Transport permease protein
HUT09_06575	COG3830	Belongs to the UPF0237 family
HUT09_06575	COG0560	Phosphoserine phosphatase
HUT09_06595	COG2186	Transcriptional regulator
HUT09_06605	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HUT09_06610	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_06625	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HUT09_06645	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HUT09_06650	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT09_06665	COG1063	alcohol dehydrogenase
HUT09_06700	COG3387	PFAM Glycoside hydrolase 15-related
HUT09_06740	COG1024	Enoyl-CoA hydratase
HUT09_06750	COG0488	(ABC) transporter
HUT09_06775	COG0235	Class ii aldolase
HUT09_06790	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HUT09_06795	COG1492	cobalamin metabolic process
HUT09_06810	COG1797	cobyrinic acid a,c-diamide synthase activity
HUT09_06835	COG1104	cysteine desulfurase activity
HUT09_06850	COG1917	Cupin 2, conserved barrel domain protein
HUT09_06865	COG1902	pentaerythritol trinitrate reductase activity
HUT09_06870	COG1846	Transcriptional regulator
HUT09_06895	COG1414	Transcriptional regulator
HUT09_06910	COG4585	Histidine kinase
HUT09_06915	COG2197	response regulator
HUT09_06920	COG0768	penicillin binding
HUT09_06925	COG2252	PERMEase
HUT09_06940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_06950	COG0431	NADPH-dependent FMN reductase
HUT09_06965	COG0583	DNA-binding transcription factor activity
HUT09_06975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT09_07000	COG0515	serine threonine protein kinase
HUT09_07000	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT09_07005	COG0515	serine threonine protein kinase
HUT09_07005	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT09_07025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT09_07030	COG2171	N-acyltransferase activity
HUT09_07035	COG3226	Transcriptional regulator
HUT09_07055	COG2151	metal-sulfur cluster biosynthetic enzyme
HUT09_07060	COG0822	iron-sulfur transferase activity
HUT09_07065	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUT09_07070	COG0396	ATPase activity
HUT09_07080	COG0719	Fe-S assembly protein
HUT09_07095	COG1131	(ABC) transporter
HUT09_07115	COG0109	protoheme IX farnesyltransferase activity
HUT09_07125	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUT09_07140	COG0363	glucosamine-6-phosphate deaminase activity
HUT09_07150	COG4195	phage-related replication protein
HUT09_07165	COG0166	Belongs to the GPI family
HUT09_07175	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HUT09_07180	COG0149	triose-phosphate isomerase activity
HUT09_07185	COG0126	phosphoglycerate kinase activity
HUT09_07190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HUT09_07195	COG1481	regulation of sporulation
HUT09_07200	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HUT09_07205	COG1660	Displays ATPase and GTPase activities
HUT09_07210	COG0322	excinuclease ABC activity
HUT09_07235	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT09_07265	COG0556	nucleotide-excision repair
HUT09_07275	COG0584	glycerophosphoryl diester phosphodiesterase
HUT09_07280	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUT09_07290	COG2814	Major facilitator Superfamily
HUT09_07300	COG2313	pseudouridylate synthase activity
HUT09_07320	COG0436	Aminotransferase
HUT09_07340	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUT09_07360	COG0237	dephospho-CoA kinase activity
HUT09_07380	COG2226	methyltransferase
HUT09_07385	COG1643	Atp-dependent helicase
HUT09_07420	COG2050	protein possibly involved in aromatic compounds catabolism
HUT09_07475	COG0737	Belongs to the 5'-nucleotidase family
HUT09_07495	COG0659	secondary active sulfate transmembrane transporter activity
HUT09_07505	COG2824	Alkylphosphonate utilization operon protein PhnA
HUT09_07525	COG0287	Prephenate dehydrogenase
HUT09_07525	COG1605	Chorismate mutase
HUT09_07560	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_07565	COG1024	Enoyl-CoA hydratase
HUT09_07590	COG1278	Cold shock
HUT09_07595	COG0183	Belongs to the thiolase family
HUT09_07600	COG1309	transcriptional regulator
HUT09_07605	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_07610	COG1960	acyl-CoA dehydrogenase activity
HUT09_07615	COG1960	acyl-CoA dehydrogenase activity
HUT09_07630	COG2304	oxidoreductase activity
HUT09_07635	COG0705	Rhomboid family
HUT09_07645	COG0070	glutamate synthase
HUT09_07645	COG0069	glutamate synthase activity
HUT09_07645	COG0067	glutamate synthase
HUT09_07655	COG1397	ADP-ribosylglycohydrolase
HUT09_07675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT09_07680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT09_07690	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HUT09_07700	COG0159	tryptophan synthase activity
HUT09_07705	COG0133	tryptophan synthase activity
HUT09_07715	COG0134	indole-3-glycerol-phosphate synthase activity
HUT09_07735	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUT09_07740	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HUT09_07750	COG2508	Transcriptional regulator
HUT09_07765	COG0107	imidazoleglycerol-phosphate synthase activity
HUT09_07770	COG0251	oxidation-reduction process
HUT09_07775	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HUT09_07780	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HUT09_07790	COG0131	Imidazoleglycerol-phosphate dehydratase
HUT09_07795	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT09_07800	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HUT09_07840	COG1432	Conserved Protein
HUT09_07850	COG0587	DNA-directed DNA polymerase activity
HUT09_07900	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HUT09_07910	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HUT09_07915	COG3599	regulation of cell shape
HUT09_07925	COG1799	cell septum assembly
HUT09_07930	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HUT09_07950	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HUT09_07960	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HUT09_07965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUT09_07975	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HUT09_07980	COG0768	penicillin binding
HUT09_07990	COG0275	rRNA processing
HUT09_08000	COG0714	Associated with various cellular activities
HUT09_08020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT09_08030	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HUT09_08035	COG1511	domain protein
HUT09_08065	COG0352	thiamine-phosphate diphosphorylase activity
HUT09_08085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT09_08085	COG2022	thiamine diphosphate biosynthetic process
HUT09_08095	COG2022	thiamine diphosphate biosynthetic process
HUT09_08100	COG0515	serine threonine protein kinase
HUT09_08100	COG2815	serine threonine protein kinase
HUT09_08105	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HUT09_08110	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUT09_08115	COG2193	ferroxidase activity
HUT09_08125	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HUT09_08140	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUT09_08150	COG4585	Histidine kinase
HUT09_08175	COG1940	carbohydrate kinase activity
HUT09_08185	COG0003	Pfam Anion-transporting ATPase
HUT09_08250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUT09_08255	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HUT09_08260	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HUT09_08265	COG0723	plastoquinol--plastocyanin reductase activity
HUT09_08270	COG2010	Cytochrome c
HUT09_08275	COG1845	cytochrome c oxidase, subunit III
HUT09_08285	COG1376	ErfK ybiS ycfS ynhG family protein
HUT09_08295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUT09_08300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HUT09_08305	COG1104	cysteine desulfurase activity
HUT09_08310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT09_08330	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HUT09_08340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUT09_08345	COG2197	response regulator
HUT09_08350	COG4585	Histidine kinase
HUT09_08370	COG4106	trans-aconitate 2-methyltransferase activity
HUT09_08375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT09_08390	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HUT09_08395	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUT09_08395	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HUT09_08410	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HUT09_08415	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HUT09_08420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUT09_08435	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HUT09_08455	COG1090	epimerase
HUT09_08470	COG0321	lipoyl(octanoyl) transferase activity
HUT09_08475	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HUT09_08505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT09_08525	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT09_08530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT09_08555	COG0745	RESPONSE REGULATOR receiver
HUT09_08560	COG2409	Drug exporters of the RND superfamily
HUT09_08565	COG4585	Histidine kinase
HUT09_08570	COG2197	response regulator
HUT09_08630	COG0366	Alpha amylase catalytic
HUT09_08635	COG3833	ABC-type maltose transport systems, permease component
HUT09_08650	COG1609	Transcriptional regulator
HUT09_08665	COG0531	amino acid
HUT09_08675	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HUT09_08685	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT09_08695	COG0477	Major facilitator Superfamily
HUT09_08700	COG1309	transcriptional regulator
HUT09_08725	COG0174	glutamine synthetase
HUT09_08750	COG2132	Multicopper oxidase
HUT09_08755	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HUT09_08755	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT09_08760	COG2814	Major facilitator Superfamily
HUT09_08775	COG0477	Major facilitator Superfamily
HUT09_08780	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HUT09_08800	COG1994	Peptidase M50
HUT09_08860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUT09_08865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_08870	COG1120	ATPase activity
HUT09_08890	COG1834	amidinotransferase
HUT09_08905	COG2814	Major facilitator Superfamily
HUT09_08915	COG3540	Alkaline phosphatase
HUT09_08920	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_08930	COG0384	phenazine biosynthesis protein PhzF
HUT09_08960	COG0456	acetyltransferase
HUT09_08990	COG0557	exoribonuclease II activity
HUT09_08995	COG3022	response to hydroperoxide
HUT09_09000	COG0800	Aldolase
HUT09_09020	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HUT09_09040	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_09050	COG2030	dehydratase
HUT09_09060	COG0183	Belongs to the thiolase family
HUT09_09065	COG1960	acyl-CoA dehydrogenase activity
HUT09_09070	COG2146	nitrite reductase [NAD(P)H] activity
HUT09_09070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT09_09075	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT09_09080	COG0243	molybdopterin cofactor binding
HUT09_09085	COG2223	nitrite transmembrane transporter activity
HUT09_09090	COG0477	Major facilitator Superfamily
HUT09_09110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_09140	COG0438	transferase activity, transferring glycosyl groups
HUT09_09145	COG1309	transcriptional regulator
HUT09_09215	COG3845	ABC transporter
HUT09_09225	COG0183	Belongs to the thiolase family
HUT09_09230	COG2124	cytochrome p450
HUT09_09265	COG0390	transport system, permease component
HUT09_09280	COG2259	Doxx family
HUT09_09360	COG1358	cellular component organization or biogenesis
HUT09_09405	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HUT09_09415	COG0477	Major facilitator Superfamily
HUT09_09420	COG1309	transcriptional regulator
HUT09_09435	COG4585	Histidine kinase
HUT09_09440	COG2197	response regulator
HUT09_09455	COG0667	Aldo Keto reductase
HUT09_09460	COG0789	Transcriptional regulator
HUT09_09485	COG1741	Belongs to the pirin family
HUT09_09500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT09_09505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT09_09510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT09_09540	COG1309	transcriptional regulator
HUT09_09545	COG1280	lysine exporter protein (LysE YggA)
HUT09_09555	COG1764	response to oxidative stress
HUT09_09560	COG2130	NADP-dependent
HUT09_09590	COG1522	sequence-specific DNA binding
HUT09_09605	COG3291	Pkd domain containing protein
HUT09_09610	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_09615	COG0825	malonyl-CoA metabolic process
HUT09_09615	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HUT09_09620	COG1309	transcriptional regulator
HUT09_09625	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_09640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT09_09655	COG0154	amidase activity
HUT09_09675	COG1960	acyl-CoA dehydrogenase activity
HUT09_09685	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HUT09_09695	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_09700	COG2175	clavaminate synthase activity
HUT09_09710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT09_09775	COG1070	Carbohydrate kinase
HUT09_09795	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUT09_09800	COG0358	DNA primase activity
HUT09_09805	COG2226	methyltransferase
HUT09_09815	COG0477	Major facilitator Superfamily
HUT09_09825	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HUT09_09835	COG2949	membrane
HUT09_09840	COG0243	molybdopterin cofactor binding
HUT09_09885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT09_09890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT09_09890	COG2146	nitrite reductase [NAD(P)H] activity
HUT09_09915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT09_09915	COG0574	Belongs to the PEP-utilizing enzyme family
HUT09_09925	COG3842	ATPase activity
HUT09_09930	COG2011	ABC-type metal ion transport system permease component
HUT09_09945	COG2188	Transcriptional regulator
HUT09_09960	COG1191	sigma factor activity
HUT09_09975	COG0667	Aldo Keto reductase
HUT09_09995	COG0477	Major facilitator Superfamily
HUT09_10015	COG2226	methyltransferase
HUT09_10020	COG2318	DinB family
HUT09_10025	COG2066	Belongs to the glutaminase family
HUT09_10035	COG3655	Transcriptional regulator
HUT09_10055	COG2267	carboxylic ester hydrolase activity
HUT09_10070	COG0784	Response regulator, receiver
HUT09_10075	COG4251	negative regulation of phosphorylation
HUT09_10080	COG2204	response regulator
HUT09_10180	COG4221	oxidoreductase activity
HUT09_10210	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT09_10235	COG0423	glycine-tRNA ligase activity
HUT09_10245	COG1121	(ABC) transporter
HUT09_10250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUT09_10260	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUT09_10265	COG1381	Involved in DNA repair and RecF pathway recombination
HUT09_10280	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT09_10295	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HUT09_10315	COG2315	Protein conserved in bacteria
HUT09_10325	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HUT09_10335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT09_10345	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT09_10350	COG1234	tRNA 3'-trailer cleavage
HUT09_10355	COG0537	adenosine 5'-monophosphoramidase activity
HUT09_10370	COG0484	heat shock protein binding
HUT09_10375	COG1420	regulation of RNA biosynthetic process
HUT09_10405	COG1022	Amp-dependent synthetase and ligase
HUT09_10410	COG0481	GTPase activity
HUT09_10415	COG0268	Binds directly to 16S ribosomal RNA
HUT09_10450	COG1555	photosystem II stabilization
HUT09_10455	COG1307	EDD domain protein, DegV family
HUT09_10465	COG0495	leucyl-tRNA aminoacylation
HUT09_10500	COG0588	phosphoglycerate mutase activity
HUT09_10505	COG0799	negative regulation of ribosome biogenesis
HUT09_10515	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HUT09_10530	COG0501	Belongs to the peptidase M48B family
HUT09_10545	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HUT09_10555	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HUT09_10560	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT09_10580	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HUT09_10585	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HUT09_10590	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HUT09_10625	COG0673	inositol 2-dehydrogenase activity
HUT09_10635	COG1530	ribonuclease E activity
HUT09_10660	COG0772	Belongs to the SEDS family
HUT09_10680	COG1077	Cell shape determining protein MreB Mrl
HUT09_10685	COG0105	UTP biosynthetic process
HUT09_10695	COG0285	dihydrofolate synthase activity
HUT09_10700	COG0525	valine-tRNA ligase activity
HUT09_10710	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HUT09_10715	COG0740	serine-type endopeptidase activity
HUT09_10720	COG0740	serine-type endopeptidase activity
HUT09_10725	COG0544	peptidyl-prolyl cis-trans isomerase activity
HUT09_10745	COG3594	Acyltransferase
HUT09_10755	COG0475	glutathione-regulated potassium exporter activity
HUT09_10765	COG4552	Acetyltransferase involved in intracellular survival and related
HUT09_10780	COG1113	amino acid transport
HUT09_10785	COG1268	BioY protein
HUT09_10790	COG1113	amino acid transport
HUT09_10795	COG1113	amino acid transport
HUT09_10805	COG0584	glycerophosphoryl diester phosphodiesterase
HUT09_10810	COG0783	Belongs to the Dps family
HUT09_10815	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HUT09_10820	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HUT09_10825	COG0640	Transcriptional regulator
HUT09_10835	COG0110	maltose O-acetyltransferase activity
HUT09_10855	COG2211	Major facilitator Superfamily
HUT09_10865	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HUT09_10900	COG4266	Belongs to the allantoicase family
HUT09_10905	COG0583	DNA-binding transcription factor activity
HUT09_10925	COG3291	Pkd domain containing protein
HUT09_10925	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HUT09_10935	COG0668	transmembrane transport
HUT09_10940	COG1940	carbohydrate kinase activity
HUT09_10950	COG1175	transmembrane transport
HUT09_10955	COG0395	ABC-type sugar transport system, permease component
HUT09_10960	COG1486	melibiose metabolic process
HUT09_10975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT09_11005	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT09_11010	COG2346	COG2346, Truncated hemoglobins
HUT09_11035	COG0629	single-stranded DNA binding
HUT09_11080	COG1131	(ABC) transporter
HUT09_11100	COG3962	Belongs to the TPP enzyme family
HUT09_11105	COG3718	enzyme involved in inositol metabolism
HUT09_11120	COG1082	Xylose isomerase domain protein TIM barrel
HUT09_11125	COG2318	DinB family
HUT09_11140	COG2409	Drug exporters of the RND superfamily
HUT09_11165	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUT09_11240	COG0673	inositol 2-dehydrogenase activity
HUT09_11245	COG1609	Transcriptional regulator
HUT09_11270	COG0515	serine threonine protein kinase
HUT09_11305	COG1404	Belongs to the peptidase S8 family
HUT09_11320	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT09_11345	COG0028	Belongs to the TPP enzyme family
HUT09_11355	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT09_11460	COG1946	Acyl-CoA thioesterase
HUT09_11480	COG2755	lipolytic protein G-D-S-L family
HUT09_11480	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HUT09_11495	COG2311	Membrane
HUT09_11505	COG1309	transcriptional regulator
HUT09_11510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT09_11525	COG1960	acyl-CoA dehydrogenase activity
HUT09_11545	COG1733	regulation of RNA biosynthetic process
HUT09_11565	COG0076	glutamate decarboxylase activity
HUT09_11570	COG3486	L-lysine 6-monooxygenase (NADPH) activity
HUT09_11600	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT09_11605	COG0589	response to stress
HUT09_11610	COG4977	sequence-specific DNA binding
HUT09_11625	COG3397	chitin binding
HUT09_11645	COG0395	ABC-type sugar transport system, permease component
HUT09_11660	COG2985	domain, Protein
HUT09_11665	COG2985	domain, Protein
HUT09_11675	COG3509	depolymerase
HUT09_11675	COG3693	PFAM glycoside hydrolase, family 10
HUT09_11760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_11775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT09_11780	COG0765	amino acid transport
HUT09_11785	COG0765	amino acid transport
HUT09_11790	COG1126	abc transporter atp-binding protein
HUT09_11805	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_11810	COG3397	chitin binding
HUT09_11890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT09_11895	COG2188	Transcriptional regulator
HUT09_11915	COG1940	carbohydrate kinase activity
HUT09_11920	COG0673	inositol 2-dehydrogenase activity
HUT09_11925	COG4702	Belongs to the UPF0303 family
HUT09_11935	COG0706	membrane insertase activity
HUT09_11935	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion
HUT09_11945	COG3764	Sortase (surface protein transpeptidase)
HUT09_12005	COG0583	DNA-binding transcription factor activity
HUT09_12050	COG2267	carboxylic ester hydrolase activity
HUT09_12065	COG0697	spore germination
HUT09_12075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT09_12085	COG2313	pseudouridylate synthase activity
HUT09_12090	COG2733	membrane
HUT09_12120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT09_12145	COG0477	Major facilitator Superfamily
HUT09_12155	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HUT09_12165	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HUT09_12170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUT09_12175	COG1263	PTS System
HUT09_12180	COG1263	PTS System
HUT09_12185	COG1234	tRNA 3'-trailer cleavage
HUT09_12205	COG1120	ATPase activity
HUT09_12210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_12225	COG1113	amino acid transport
HUT09_12235	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HUT09_12245	COG1335	isochorismatase
HUT09_12280	COG0277	FAD linked oxidase domain protein
HUT09_12290	COG3185	4-Hydroxyphenylpyruvate dioxygenase
HUT09_12300	COG1174	glycine betaine transport
HUT09_12310	COG1174	glycine betaine transport
HUT09_12315	COG1732	Glycine betaine
HUT09_12335	COG3480	Lon protease (S16) C-terminal proteolytic domain
HUT09_12350	COG3654	unkown
HUT09_12390	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HUT09_12395	COG0395	ABC-type sugar transport system, permease component
HUT09_12415	COG1678	Uncharacterized ACR, COG1678
HUT09_12420	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUT09_12435	COG0776	regulation of translation
HUT09_12445	COG3973	AAA domain
HUT09_12445	COG3973	AAA domain
HUT09_12470	COG2223	nitrite transmembrane transporter activity
HUT09_12490	COG0583	DNA-binding transcription factor activity
HUT09_12510	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HUT09_12515	COG0793	Belongs to the peptidase S41A family
HUT09_12520	COG2177	Part of the ABC transporter FtsEX involved in
HUT09_12525	COG2884	Cell division ATP-binding protein ftsE
HUT09_12540	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUT09_12545	COG0515	serine threonine protein kinase
HUT09_12550	COG0515	serine threonine protein kinase
HUT09_12570	COG0395	ABC-type sugar transport system, permease component
HUT09_12575	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT09_12575	COG0463	Glycosyl transferase, family 2
HUT09_12580	COG0438	transferase activity, transferring glycosyl groups
HUT09_12585	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT09_12590	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT09_12600	COG1073	alpha beta
HUT09_12600	COG2226	methyltransferase
HUT09_12605	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT09_12610	COG1216	Glycosyl transferase, family 2
HUT09_12620	COG1309	transcriptional regulator
HUT09_12630	COG1134	teichoic acid transport
HUT09_12635	COG2902	Dehydrogenase
HUT09_12660	COG0653	protein targeting
HUT09_12675	COG2197	response regulator
HUT09_12680	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HUT09_12690	COG0823	Involved in the tonB-independent uptake of proteins
HUT09_12695	COG5000	phosphorelay sensor kinase activity
HUT09_12695	COG5002	protein histidine kinase activity
HUT09_12700	COG0745	RESPONSE REGULATOR receiver
HUT09_12705	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HUT09_12725	COG0714	Associated with various cellular activities
HUT09_12765	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HUT09_12785	COG2835	tetraacyldisaccharide 4'-kinase activity
HUT09_12790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT09_12825	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HUT09_12830	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
HUT09_12830	COG0778	Nitroreductase
HUT09_12840	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUT09_12855	COG1316	TRANSCRIPTIONal
HUT09_12860	COG1316	TRANSCRIPTIONal
HUT09_12875	COG1316	TRANSCRIPTIONal
HUT09_12885	COG1316	TRANSCRIPTIONal
HUT09_12925	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUT09_12960	COG2205	protein histidine kinase activity
HUT09_12965	COG0745	RESPONSE REGULATOR receiver
HUT09_12970	COG3104	oligopeptide transport
HUT09_13000	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT09_13005	COG1191	sigma factor activity
HUT09_13010	COG1228	amidohydrolase
HUT09_13025	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HUT09_13075	COG2755	lipolytic protein G-D-S-L family
HUT09_13080	COG0183	Belongs to the thiolase family
HUT09_13105	COG1136	(ABC) transporter
HUT09_13105	COG0577	efflux transmembrane transporter activity
HUT09_13110	COG1136	(ABC) transporter
HUT09_13110	COG0577	efflux transmembrane transporter activity
HUT09_13115	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT09_13120	COG1252	NADH dehydrogenase
HUT09_13140	COG0148	phosphopyruvate hydratase activity
HUT09_13155	COG2124	cytochrome p450
HUT09_13175	COG0515	serine threonine protein kinase
HUT09_13175	COG2815	serine threonine protein kinase
HUT09_13195	COG1335	isochorismatase
HUT09_13270	COG1473	amidohydrolase
HUT09_13325	COG3903	Transcriptional regulator
HUT09_13325	COG3629	intracellular signal transduction
HUT09_13335	COG0577	efflux transmembrane transporter activity
HUT09_13335	COG1136	(ABC) transporter
HUT09_13340	COG1136	(ABC) transporter
HUT09_13350	COG2814	Major facilitator Superfamily
HUT09_13395	COG2124	cytochrome p450
HUT09_13425	COG4585	Histidine kinase
HUT09_13440	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HUT09_13445	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUT09_13450	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HUT09_13455	COG0193	aminoacyl-tRNA hydrolase activity
HUT09_13465	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HUT09_13490	COG4106	trans-aconitate 2-methyltransferase activity
HUT09_13500	COG2197	response regulator
HUT09_13510	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HUT09_13525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT09_13555	COG0488	(ABC) transporter
HUT09_13560	COG2161	toxin-antitoxin pair type II binding
HUT09_13565	COG4115	mRNA cleavage
HUT09_13580	COG2813	Specifically methylates the guanine in position
HUT09_13585	COG2318	DinB family
HUT09_13590	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HUT09_13595	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUT09_13605	COG0084	hydrolase, TatD family'
HUT09_13635	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT09_13685	COG0442	prolyl-tRNA aminoacylation
HUT09_13720	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_13730	COG1122	ATPase activity
HUT09_13740	COG0310	cobalt ion transport
HUT09_13750	COG1846	Transcriptional regulator
HUT09_13770	COG2409	Drug exporters of the RND superfamily
HUT09_13780	COG0793	Belongs to the peptidase S41A family
HUT09_13780	COG4946	Tricorn protease homolog
HUT09_13800	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_13810	COG2072	flavoprotein involved in K transport
HUT09_13820	COG0708	Exodeoxyribonuclease III
HUT09_13830	COG2340	Cysteine-rich secretory protein family
HUT09_13860	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUT09_13865	COG0315	cyclic pyranopterin monophosphate synthase activity
HUT09_13875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HUT09_13880	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HUT09_13890	COG3263	regulation of cellular component size
HUT09_13905	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HUT09_13915	COG1970	mechanosensitive ion channel activity
HUT09_13935	COG0437	4 iron, 4 sulfur cluster binding
HUT09_13940	COG0243	molybdopterin cofactor binding
HUT09_13960	COG0477	Major facilitator Superfamily
HUT09_13980	COG3384	dioxygenase
HUT09_13985	COG1846	Transcriptional regulator
HUT09_14005	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_14050	COG1686	Belongs to the peptidase S11 family
HUT09_14110	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HUT09_14125	COG0768	penicillin binding
HUT09_14185	COG0667	Aldo Keto reductase
HUT09_14195	COG3866	Pectate lyase
HUT09_14200	COG1653	transport
HUT09_14215	COG0395	ABC-type sugar transport system, permease component
HUT09_14235	COG1802	Transcriptional regulator
HUT09_14240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT09_14290	COG0183	Belongs to the thiolase family
HUT09_14295	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_14310	COG1309	transcriptional regulator
HUT09_14340	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_14370	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HUT09_14385	COG0163	prenyltransferase activity
HUT09_14395	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HUT09_14400	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HUT09_14410	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_14415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUT09_14420	COG1333	cytochrome c biogenesis protein
HUT09_14425	COG0785	Cytochrome C biogenesis protein
HUT09_14440	COG2382	esterase
HUT09_14445	COG0406	alpha-ribazole phosphatase activity
HUT09_14450	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUT09_14480	COG1116	anion transmembrane transporter activity
HUT09_14495	COG1690	Belongs to the RtcB family
HUT09_14515	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
HUT09_14520	COG0018	arginyl-trna synthetase
HUT09_14555	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HUT09_14575	COG0113	porphobilinogen synthase activity
HUT09_14580	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUT09_14580	COG1648	precorrin-2 dehydrogenase activity
HUT09_14585	COG0181	hydroxymethylbilane synthase activity
HUT09_14590	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HUT09_14595	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HUT09_14650	COG2223	nitrite transmembrane transporter activity
HUT09_14655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT09_14675	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HUT09_14685	COG0842	Transport permease protein
HUT09_14685	COG1129	ABC transporter
HUT09_14695	COG4991	sh3 domain protein
HUT09_14705	COG0129	dihydroxy-acid dehydratase activity
HUT09_14710	COG1309	transcriptional regulator
HUT09_14715	COG1082	Xylose isomerase domain protein TIM barrel
HUT09_14720	COG0248	Ppx GppA phosphatase
HUT09_14740	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HUT09_14750	COG1194	a g-specific adenine glycosylase
HUT09_14755	COG1595	DNA-templated transcription, initiation
HUT09_14765	COG0745	RESPONSE REGULATOR receiver
HUT09_14770	COG2205	protein histidine kinase activity
HUT09_14775	COG0739	heme binding
HUT09_14805	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HUT09_14825	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HUT09_14835	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HUT09_14840	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HUT09_14865	COG2197	response regulator
HUT09_14880	COG0649	NAD binding
HUT09_14890	COG1732	Glycine betaine
HUT09_14895	COG1174	glycine betaine transport
HUT09_14900	COG1174	glycine betaine transport
HUT09_14905	COG0517	IMP dehydrogenase activity
HUT09_14905	COG1125	glycine betaine transport
HUT09_14915	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUT09_14915	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HUT09_14930	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HUT09_14945	COG0302	gtp cyclohydrolase
HUT09_14960	COG0037	tRNA processing
HUT09_14970	COG2027	D-alanyl-D-alanine carboxypeptidase
HUT09_14975	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HUT09_14985	COG0586	Pfam SNARE associated Golgi protein
HUT09_14990	COG0393	Putative heavy-metal-binding
HUT09_15000	COG0655	NAD(P)H dehydrogenase (quinone) activity
HUT09_15005	COG0076	glutamate decarboxylase activity
HUT09_15025	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_15065	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUT09_15065	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUT09_15095	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HUT09_15120	COG0726	polysaccharide deacetylase
HUT09_15140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT09_15145	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT09_15180	COG3903	Transcriptional regulator
HUT09_15180	COG3629	intracellular signal transduction
HUT09_15195	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HUT09_15200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HUT09_15205	COG1754	DNA topoisomerase type I activity
HUT09_15205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HUT09_15215	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT09_15225	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HUT09_15235	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT09_15240	COG1111	helicase
HUT09_15240	COG1205	dead DEAH box helicase
HUT09_15375	COG0288	reversible hydration of carbon dioxide
HUT09_15380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT09_15385	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUT09_15395	COG2267	carboxylic ester hydrolase activity
HUT09_15420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT09_15445	COG0003	Pfam Anion-transporting ATPase
HUT09_15455	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HUT09_15460	COG1610	YqeY-like protein
HUT09_15465	COG1408	metallophosphoesterase
HUT09_15485	COG2755	lipolytic protein G-D-S-L family
HUT09_15495	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HUT09_15515	COG1595	DNA-templated transcription, initiation
HUT09_15555	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HUT09_15560	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HUT09_15575	COG1802	Transcriptional regulator
HUT09_15580	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT09_15585	COG0693	protein deglycase activity
HUT09_15595	COG0515	serine threonine protein kinase
HUT09_15595	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT09_15600	COG0738	Major facilitator superfamily
HUT09_15610	COG3226	Transcriptional regulator
HUT09_15660	COG0592	DNA-directed DNA polymerase activity
HUT09_15695	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HUT09_15700	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HUT09_15725	COG2197	response regulator
HUT09_15745	COG3844	kynureninase activity
HUT09_15760	COG0477	Major facilitator Superfamily
HUT09_15770	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HUT09_15775	COG0191	fructose-bisphosphate aldolase activity
HUT09_15780	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HUT09_15795	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HUT09_15820	COG0542	response to heat
HUT09_15845	COG0789	Transcriptional regulator
HUT09_15850	COG0484	heat shock protein binding
HUT09_15855	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HUT09_15860	COG0443	Heat shock 70 kDa protein
HUT09_15865	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HUT09_15870	COG2181	nitrate reductase activity
HUT09_15870	COG0247	lactate metabolic process
HUT09_15890	COG0717	Belongs to the dCTP deaminase family
HUT09_15935	COG1940	carbohydrate kinase activity
HUT09_15950	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_15955	COG1063	alcohol dehydrogenase
HUT09_15960	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HUT09_15965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT09_15985	COG2205	protein histidine kinase activity
HUT09_15990	COG0745	RESPONSE REGULATOR receiver
HUT09_16005	COG1376	ErfK ybiS ycfS ynhG family protein
HUT09_16010	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUT09_16035	COG2130	NADP-dependent
HUT09_16055	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUT09_16075	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_16090	COG0367	asparagine synthase
HUT09_16105	COG1902	pentaerythritol trinitrate reductase activity
HUT09_16130	COG1686	Belongs to the peptidase S11 family
HUT09_16135	COG2205	protein histidine kinase activity
HUT09_16140	COG0745	RESPONSE REGULATOR receiver
HUT09_16170	COG0745	RESPONSE REGULATOR receiver
HUT09_16180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT09_16190	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HUT09_16195	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HUT09_16205	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUT09_16205	COG0519	Catalyzes the synthesis of GMP from XMP
HUT09_16215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT09_16230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_16235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_16245	COG1695	Transcriptional regulator
HUT09_16255	COG0667	Aldo Keto reductase
HUT09_16265	COG1609	Transcriptional regulator
HUT09_16270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT09_16295	COG2124	cytochrome p450
HUT09_16315	COG3585	molybdate ion transport
HUT09_16340	COG0531	amino acid
HUT09_16350	COG0475	glutathione-regulated potassium exporter activity
HUT09_16360	COG2409	Drug exporters of the RND superfamily
HUT09_16365	COG3594	Acyltransferase
HUT09_16380	COG0513	Belongs to the DEAD box helicase family
HUT09_16385	COG1278	Cold shock
HUT09_16425	COG5002	protein histidine kinase activity
HUT09_16430	COG0745	RESPONSE REGULATOR receiver
HUT09_16465	COG0454	-acetyltransferase
HUT09_16490	COG2268	Band 7 protein
HUT09_16530	COG0490	domain, Protein
HUT09_16535	COG0475	glutathione-regulated potassium exporter activity
HUT09_16560	COG2255	four-way junction helicase activity
HUT09_16570	COG0180	Tryptophanyl-tRNA synthetase
HUT09_16580	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HUT09_16585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_16615	COG0431	NADPH-dependent FMN reductase
HUT09_16645	COG2205	protein histidine kinase activity
HUT09_16650	COG0745	RESPONSE REGULATOR receiver
HUT09_16655	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUT09_16665	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HUT09_16680	COG1741	Belongs to the pirin family
HUT09_16690	COG1960	acyl-CoA dehydrogenase activity
HUT09_16700	COG1362	aminopeptidase activity
HUT09_16725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT09_16740	COG1802	Transcriptional regulator
HUT09_16760	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT09_16765	COG0022	dehydrogenase e1 component
HUT09_16790	COG0515	serine threonine protein kinase
HUT09_16795	COG0515	serine threonine protein kinase
HUT09_16810	COG4591	ABC-type transport system involved in lipoprotein release permease component
HUT09_16810	COG1136	(ABC) transporter
HUT09_16825	COG3321	synthase
HUT09_16825	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_16825	COG0604	alcohol dehydrogenase
HUT09_16840	COG0746	molybdenum cofactor guanylyltransferase activity
HUT09_16860	COG1522	sequence-specific DNA binding
HUT09_16865	COG1309	transcriptional regulator
HUT09_16890	COG3396	Phenylacetate-CoA oxygenase
HUT09_16895	COG3460	Phenylacetate-CoA oxygenase
HUT09_16900	COG3396	Phenylacetate-CoA oxygenase
HUT09_16905	COG2151	metal-sulfur cluster biosynthetic enzyme
HUT09_16910	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT09_16920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUT09_16935	COG1733	regulation of RNA biosynthetic process
HUT09_16940	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HUT09_16955	COG1716	ATPase activity
HUT09_16960	COG1716	ATPase activity
HUT09_16975	COG0768	penicillin binding
HUT09_16980	COG0515	serine threonine protein kinase
HUT09_16985	COG3764	Sortase (surface protein transpeptidase)
HUT09_16990	COG3764	Sortase (surface protein transpeptidase)
HUT09_17005	COG3764	Sortase (surface protein transpeptidase)
HUT09_17020	COG0705	Rhomboid family
HUT09_17065	COG0515	serine threonine protein kinase
HUT09_17095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUT09_17105	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
HUT09_17110	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUT09_17115	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HUT09_17120	COG0592	DNA-directed DNA polymerase activity
HUT09_17130	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HUT09_17135	COG0594	ribonuclease P activity
HUT09_17140	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HUT09_17145	COG0706	membrane insertase activity
HUT09_17155	COG0357	Ribosomal RNA small subunit methyltransferase G
HUT09_17160	COG1192	Involved in chromosome partitioning
HUT09_17175	COG3118	belongs to the thioredoxin family
HUT09_17180	COG0492	ferredoxin-NADP+ reductase activity
HUT09_17190	COG1595	DNA-templated transcription, initiation
HUT09_17195	COG0515	serine threonine protein kinase
HUT09_17195	COG2815	serine threonine protein kinase
HUT09_17210	COG0617	tRNA 3'-terminal CCA addition
HUT09_17230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT09_17255	COG0360	Binds together with S18 to 16S ribosomal RNA
HUT09_17260	COG0629	single-stranded DNA binding
HUT09_17265	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUT09_17270	COG0359	binds to the 23S rRNA
HUT09_17275	COG0534	Mate efflux family protein
HUT09_17280	COG0305	Participates in initiation and elongation during chromosome replication
HUT09_17295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT09_17300	COG0456	acetyltransferase
HUT09_17310	COG2814	Major facilitator Superfamily
HUT09_17330	COG0626	cystathionine gamma-synthase activity
HUT09_17335	COG1950	PFAM Membrane protein of
HUT09_17340	COG0662	Cupin 2, conserved barrel domain protein
HUT09_17365	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HUT09_17375	COG3152	Membrane
HUT09_17385	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUT09_17390	COG1609	Transcriptional regulator
HUT09_17395	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT09_17400	COG1271	oxidase subunit
HUT09_17405	COG1294	oxidase, subunit
HUT09_17410	COG4988	ABC transporter
HUT09_17420	COG0561	phosphatase activity
HUT09_17430	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HUT09_17435	COG0789	Transcriptional regulator
HUT09_17450	COG1131	(ABC) transporter
HUT09_17475	COG0561	phosphatase activity
HUT09_17480	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HUT09_17490	COG2837	iron assimilation
HUT09_17495	COG2372	response to copper ion
HUT09_17505	COG1999	signal sequence binding
HUT09_17525	COG0006	proline dipeptidase activity
HUT09_17545	COG0653	protein targeting
HUT09_17585	COG1960	acyl-CoA dehydrogenase activity
HUT09_17610	COG1595	DNA-templated transcription, initiation
HUT09_17615	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_17645	COG1595	DNA-templated transcription, initiation
HUT09_17665	COG0745	RESPONSE REGULATOR receiver
HUT09_17670	COG2205	protein histidine kinase activity
HUT09_17680	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT09_17695	COG0477	Major facilitator Superfamily
HUT09_17710	COG3467	pyridoxamine 5'-phosphate
HUT09_17715	COG2353	YceI-like domain
HUT09_17740	COG1191	sigma factor activity
HUT09_17745	COG1191	sigma factor activity
HUT09_17780	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HUT09_17810	COG4941	Belongs to the sigma-70 factor family
HUT09_17870	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUT09_17875	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HUT09_17975	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HUT09_17980	COG2188	Transcriptional regulator
HUT09_18060	COG0151	Belongs to the GarS family
HUT09_18075	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HUT09_18085	COG2197	response regulator
HUT09_18120	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUT09_18125	COG0047	phosphoribosylformylglycinamidine synthase activity
HUT09_18130	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUT09_18140	COG1196	nuclear chromosome segregation
HUT09_18140	COG0741	lytic transglycosylase activity
HUT09_18140	COG0739	heme binding
HUT09_18160	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HUT09_18195	COG1643	Atp-dependent helicase
HUT09_18205	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUT09_18205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUT09_18210	COG0785	Cytochrome C biogenesis protein
HUT09_18240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUT09_18245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUT09_18255	COG0513	Belongs to the DEAD box helicase family
HUT09_18265	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUT09_18275	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HUT09_18290	COG0789	Transcriptional regulator
HUT09_18300	COG0741	lytic transglycosylase activity
HUT09_18300	COG1196	nuclear chromosome segregation
HUT09_18300	COG0739	heme binding
HUT09_18305	COG0667	Aldo Keto reductase
HUT09_18315	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HUT09_18320	COG0579	oxidoreductase
HUT09_18345	COG1252	NADH dehydrogenase
HUT09_18360	COG1846	Transcriptional regulator
HUT09_18380	COG2197	response regulator
HUT09_18385	COG4585	Histidine kinase
HUT09_18395	COG1131	(ABC) transporter
HUT09_18460	COG0739	heme binding
HUT09_18460	COG1196	nuclear chromosome segregation
HUT09_18460	COG0741	lytic transglycosylase activity
HUT09_18465	COG0671	phosphoesterase, PA-phosphatase related
HUT09_18480	COG1937	Protein conserved in bacteria
HUT09_18490	COG0306	phosphate transporter
HUT09_18510	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HUT09_18535	COG1116	anion transmembrane transporter activity
HUT09_18540	COG1725	Transcriptional regulator
HUT09_18550	COG0456	acetyltransferase
HUT09_18560	COG0737	Belongs to the 5'-nucleotidase family
HUT09_18575	COG0154	amidase activity
HUT09_18640	COG0789	Transcriptional regulator
HUT09_18655	COG0823	Involved in the tonB-independent uptake of proteins
HUT09_18675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT09_18685	COG1609	Transcriptional regulator
HUT09_18690	COG0745	RESPONSE REGULATOR receiver
HUT09_18715	COG2897	thiosulfate sulfurtransferase activity
HUT09_18750	COG3485	protocatechuate 3,4-dioxygenase
HUT09_18755	COG0735	belongs to the Fur family
HUT09_18765	COG1490	D-aminoacyl-tRNA deacylase activity
HUT09_18780	COG4552	Acetyltransferase involved in intracellular survival and related
HUT09_18830	COG0475	glutathione-regulated potassium exporter activity
HUT09_18845	COG1846	Transcriptional regulator
HUT09_18860	COG4770	biotin carboxylase activity
HUT09_18885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT09_18915	COG0736	holo-[acyl-carrier-protein] synthase activity
HUT09_18920	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT09_18945	COG2318	DinB family
HUT09_18955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_18965	COG1733	regulation of RNA biosynthetic process
HUT09_19015	COG0438	transferase activity, transferring glycosyl groups
HUT09_19120	COG1609	Transcriptional regulator
HUT09_19165	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HUT09_19175	COG0588	phosphoglycerate mutase activity
HUT09_19195	COG5002	protein histidine kinase activity
HUT09_19210	COG1329	Transcriptional regulator
HUT09_19215	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HUT09_19220	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HUT09_19230	COG0215	cysteine-tRNA ligase activity
HUT09_19235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUT09_19245	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HUT09_19255	COG3842	ATPase activity
HUT09_19270	COG3631	Ketosteroid isomerase-related protein
HUT09_19275	COG0702	epimerase
HUT09_19295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT09_19315	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HUT09_19335	COG2197	response regulator
HUT09_19340	COG4585	Histidine kinase
HUT09_19350	COG0666	response to abiotic stimulus
HUT09_19375	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUT09_19400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HUT09_19425	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HUT09_19430	COG0463	Glycosyl transferase, family 2
HUT09_19480	COG1132	(ABC) transporter
HUT09_19490	COG1595	DNA-templated transcription, initiation
HUT09_19515	COG0395	ABC-type sugar transport system, permease component
HUT09_19520	COG1175	transmembrane transport
HUT09_19565	COG4251	negative regulation of phosphorylation
HUT09_19585	COG0477	Major facilitator Superfamily
HUT09_19595	COG1263	PTS System
HUT09_19595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUT09_19600	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HUT09_19605	COG1737	Transcriptional regulator
HUT09_19645	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
HUT09_19665	COG3142	Participates in the control of copper homeostasis
HUT09_19670	COG3973	AAA domain
HUT09_19680	COG1061	Type III restriction enzyme res subunit
HUT09_19695	COG0006	proline dipeptidase activity
HUT09_19700	COG4934	collagen metabolic process
HUT09_19745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUT09_19750	COG1120	ATPase activity
HUT09_19755	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_19760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_19780	COG1278	Cold shock
HUT09_19785	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HUT09_19790	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HUT09_19800	COG2814	Major facilitator Superfamily
HUT09_19830	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUT09_19840	COG2252	PERMEase
HUT09_19850	COG1846	Transcriptional regulator
HUT09_19860	COG0667	Aldo Keto reductase
HUT09_19870	COG2267	carboxylic ester hydrolase activity
HUT09_19880	COG0515	serine threonine protein kinase
HUT09_19890	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_19895	COG0583	DNA-binding transcription factor activity
HUT09_19915	COG1595	DNA-templated transcription, initiation
HUT09_19975	COG1309	transcriptional regulator
HUT09_19985	COG0697	spore germination
HUT09_20000	COG2130	NADP-dependent
HUT09_20050	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT09_20070	COG1335	isochorismatase
HUT09_20100	COG2318	DinB family
HUT09_20110	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HUT09_20140	COG2205	protein histidine kinase activity
HUT09_20145	COG0247	lactate metabolic process
HUT09_20145	COG0277	FAD linked oxidase domain protein
HUT09_20150	COG3896	Chloramphenicol phosphotransferase-like protein
HUT09_20155	COG0583	DNA-binding transcription factor activity
HUT09_20165	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
HUT09_20175	COG0494	nUDIX hydrolase
HUT09_20190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT09_20205	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_20210	COG1024	Enoyl-CoA hydratase
HUT09_20240	COG0456	acetyltransferase
HUT09_20250	COG2124	cytochrome p450
HUT09_20275	COG0259	pyridoxamine-phosphate oxidase activity
HUT09_20285	COG0577	efflux transmembrane transporter activity
HUT09_20285	COG1136	(ABC) transporter
HUT09_20290	COG0577	efflux transmembrane transporter activity
HUT09_20290	COG1136	(ABC) transporter
HUT09_20305	COG0745	RESPONSE REGULATOR receiver
HUT09_20310	COG2205	protein histidine kinase activity
HUT09_20315	COG4821	SIS domain
HUT09_20325	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUT09_20340	COG1131	(ABC) transporter
HUT09_20395	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_20405	COG1960	acyl-CoA dehydrogenase activity
HUT09_20410	COG1960	acyl-CoA dehydrogenase activity
HUT09_20425	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_20430	COG1960	acyl-CoA dehydrogenase activity
HUT09_20480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUT09_20490	COG0346	lactoylglutathione lyase activity
HUT09_20510	COG1024	Enoyl-CoA hydratase
HUT09_20535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUT09_20545	COG0702	epimerase
HUT09_20550	COG2234	aminopeptidase activity
HUT09_20560	COG2072	flavoprotein involved in K transport
HUT09_20565	COG4592	Periplasmic binding protein
HUT09_20570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_20575	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_20595	COG0501	Belongs to the peptidase M48B family
HUT09_20600	COG0259	pyridoxamine-phosphate oxidase activity
HUT09_20610	COG1960	acyl-CoA dehydrogenase activity
HUT09_20620	COG1309	transcriptional regulator
HUT09_20645	COG1024	Enoyl-CoA hydratase
HUT09_20690	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HUT09_20700	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HUT09_20725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT09_20730	COG4521	taurine ABC transporter
HUT09_20740	COG2175	clavaminate synthase activity
HUT09_20745	COG2226	methyltransferase
HUT09_20790	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT09_20795	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT09_20800	COG0649	NAD binding
HUT09_20810	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HUT09_20815	COG1034	ATP synthesis coupled electron transport
HUT09_20820	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUT09_20825	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT09_20830	COG0839	Belongs to the complex I subunit 6 family
HUT09_20835	COG0713	ATP synthesis coupled electron transport
HUT09_20840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUT09_20850	COG1007	ATP synthesis coupled electron transport
HUT09_20855	COG0514	ATP-dependent DNA helicase (RecQ)
HUT09_20865	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT09_20875	COG3104	oligopeptide transport
HUT09_20890	COG1131	(ABC) transporter
HUT09_20920	COG0561	phosphatase activity
HUT09_20960	COG0346	lactoylglutathione lyase activity
HUT09_20990	COG0702	epimerase
HUT09_20995	COG1733	regulation of RNA biosynthetic process
HUT09_21000	COG1013	pyruvate-flavodoxin oxidoreductase activity
HUT09_21005	COG0674	pyruvate-flavodoxin oxidoreductase activity
HUT09_21005	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HUT09_21025	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT09_21030	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT09_21035	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT09_21040	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUT09_21045	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT09_21050	COG0839	Belongs to the complex I subunit 6 family
HUT09_21055	COG0713	ATP synthesis coupled electron transport
HUT09_21070	COG1007	ATP synthesis coupled electron transport
HUT09_21075	COG1970	mechanosensitive ion channel activity
HUT09_21080	COG0501	Belongs to the peptidase M48B family
HUT09_21085	COG3304	Inner membrane component domain
HUT09_21100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUT09_21105	COG1666	GTP binding
HUT09_21135	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUT09_21140	COG2030	dehydratase
HUT09_21150	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HUT09_21165	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT09_21170	COG0436	Aminotransferase
HUT09_21190	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HUT09_21195	COG0081	regulation of translation
HUT09_21205	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HUT09_21210	COG0222	ribosome binding
HUT09_21215	COG0085	RNA polymerase activity
HUT09_21220	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HUT09_21325	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HUT09_21330	COG0049	tRNA binding
HUT09_21335	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUT09_21360	COG0051	transcription antitermination factor activity, RNA binding
HUT09_21365	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HUT09_21370	COG0088	Forms part of the polypeptide exit tunnel
HUT09_21375	COG0089	rRNA binding
HUT09_21380	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HUT09_21385	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HUT09_21390	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HUT09_21395	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HUT09_21400	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HUT09_21405	COG0255	Belongs to the universal ribosomal protein uL29 family
HUT09_21410	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HUT09_21415	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HUT09_21420	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HUT09_21425	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HUT09_21430	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUT09_21435	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HUT09_21440	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HUT09_21445	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HUT09_21450	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HUT09_21455	COG1841	ribosomal large subunit assembly
HUT09_21460	COG0200	Binds to the 23S rRNA
HUT09_21470	COG0563	adenylate kinase activity
HUT09_21480	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HUT09_21485	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HUT09_21490	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HUT09_21495	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HUT09_21500	COG0202	RNA polymerase activity
HUT09_21505	COG0203	ribosomal protein L17
HUT09_21510	COG0101	tRNA pseudouridine synthase activity
HUT09_21525	COG0488	(ABC) transporter
HUT09_21530	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HUT09_21535	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HUT09_21540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT09_21550	COG1072	(Pantothenic acid kinase))
HUT09_21555	COG1404	Belongs to the peptidase S8 family
HUT09_21570	COG0747	negative chemotaxis
HUT09_21580	COG3795	YCII-related domain
HUT09_21585	COG4941	Belongs to the sigma-70 factor family
HUT09_21605	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT09_21610	COG0736	holo-[acyl-carrier-protein] synthase activity
HUT09_21620	COG3189	MarR family transcriptional regulator
HUT09_21625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUT09_21635	COG0802	atpase or kinase
HUT09_21660	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HUT09_21700	COG0726	polysaccharide deacetylase
HUT09_21710	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HUT09_21725	COG0395	ABC-type sugar transport system, permease component
HUT09_21730	COG1175	transmembrane transport
HUT09_21745	COG4221	oxidoreductase activity
HUT09_21755	COG0583	DNA-binding transcription factor activity
HUT09_21770	COG1595	DNA-templated transcription, initiation
HUT09_21780	COG0516	GMP reductase activity
HUT09_21810	COG0515	serine threonine protein kinase
HUT09_21815	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_21835	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUT09_21835	COG0519	Catalyzes the synthesis of GMP from XMP
HUT09_21865	COG2197	response regulator
HUT09_21875	COG0791	NLP P60 protein
HUT09_21900	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT09_21915	COG0714	Associated with various cellular activities
HUT09_21920	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HUT09_21925	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HUT09_21930	COG0045	succinate-CoA ligase (ADP-forming) activity
HUT09_21960	COG0138	bifunctional purine biosynthesis protein purh
HUT09_21975	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HUT09_21990	COG0039	L-malate dehydrogenase activity
HUT09_22010	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT09_22015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT09_22030	COG0754	glutathionylspermidine amidase activity
HUT09_22035	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT09_22040	COG0180	Tryptophanyl-tRNA synthetase
HUT09_22060	COG1295	ribonuclease BN
HUT09_22070	COG1408	metallophosphoesterase
HUT09_22080	COG1309	transcriptional regulator
HUT09_22105	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUT09_22110	COG1053	succinate dehydrogenase
HUT09_22120	COG2009	succinate dehydrogenase
HUT09_22145	COG1231	oxidoreductase activity
HUT09_22230	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HUT09_22245	COG1595	DNA-templated transcription, initiation
HUT09_22290	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HUT09_22300	COG1216	Glycosyl transferase, family 2
HUT09_22310	COG1083	cytidylyl-transferase
HUT09_22315	COG2089	acid synthase
HUT09_22325	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT09_22325	COG1473	amidohydrolase
HUT09_22365	COG1404	Belongs to the peptidase S8 family
HUT09_22385	COG2814	Major facilitator Superfamily
HUT09_22390	COG0583	DNA-binding transcription factor activity
HUT09_22400	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT09_22425	COG2205	protein histidine kinase activity
HUT09_22430	COG0745	RESPONSE REGULATOR receiver
HUT09_22435	COG1595	DNA-templated transcription, initiation
HUT09_22465	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_22470	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_22485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT09_22515	COG4770	biotin carboxylase activity
HUT09_22525	COG0424	maF-like protein
HUT09_22535	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT09_22550	COG1024	Enoyl-CoA hydratase
HUT09_22575	COG1376	ErfK ybiS ycfS ynhG family protein
HUT09_22595	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUT09_22620	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUT09_22645	COG1595	DNA-templated transcription, initiation
HUT09_22655	COG2198	Histidine kinase
HUT09_22655	COG5002	protein histidine kinase activity
HUT09_22655	COG0784	Response regulator, receiver
HUT09_22665	COG2172	sigma factor antagonist activity
HUT09_22670	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT09_22675	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT09_22680	COG2255	four-way junction helicase activity
HUT09_22685	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUT09_22700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUT09_22710	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT09_22730	COG1331	Highly conserved protein containing a thioredoxin domain
HUT09_22740	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
HUT09_22805	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HUT09_22820	COG1414	Transcriptional regulator
HUT09_22825	COG0251	oxidation-reduction process
HUT09_22830	COG2610	gluconate transmembrane transporter activity
HUT09_22865	COG2894	cell division
HUT09_22895	COG3920	Histidine kinase
HUT09_22900	COG2197	response regulator
HUT09_22920	COG2885	chlorophyll binding
HUT09_22980	COG0667	Aldo Keto reductase
HUT09_22985	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUT09_22990	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HUT09_23005	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT09_23010	COG0450	alkyl hydroperoxide reductase
HUT09_23025	COG1136	(ABC) transporter
HUT09_23045	COG4499	WXG100 protein secretion system (Wss), protein YukC
HUT09_23045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT09_23060	COG0114	fumarate hydratase activity
HUT09_23070	COG1362	aminopeptidase activity
HUT09_23075	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HUT09_23075	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HUT09_23100	COG0778	Nitroreductase
HUT09_23105	COG1722	exodeoxyribonuclease VII activity
HUT09_23110	COG1570	exodeoxyribonuclease VII activity
HUT09_23120	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HUT09_23135	COG0012	GTP binding
HUT09_23195	COG0789	Transcriptional regulator
HUT09_23200	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUT09_23240	COG1842	Phage shock protein A
HUT09_23250	COG0463	Glycosyl transferase, family 2
HUT09_23260	COG4941	Belongs to the sigma-70 factor family
HUT09_23265	COG3795	YCII-related domain
HUT09_23355	COG0148	phosphopyruvate hydratase activity
HUT09_23375	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUT09_23405	COG0395	ABC-type sugar transport system, permease component
HUT09_23410	COG1175	transmembrane transport
HUT09_23425	COG2050	protein possibly involved in aromatic compounds catabolism
HUT09_23450	COG0601	transmembrane transport
HUT09_23455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT09_23465	COG4608	Belongs to the ABC transporter superfamily
HUT09_23470	COG4166	transmembrane transport
HUT09_23475	COG0601	transmembrane transport
HUT09_23490	COG4608	Belongs to the ABC transporter superfamily
HUT09_23505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT09_23520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUT09_23535	COG0110	maltose O-acetyltransferase activity
HUT09_23550	COG0515	serine threonine protein kinase
HUT09_23560	COG1132	(ABC) transporter
HUT09_23565	COG1132	(ABC) transporter
HUT09_23570	COG2197	response regulator
HUT09_23575	COG2912	Transglutaminase-like superfamily
HUT09_23605	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT09_23610	COG1611	Belongs to the LOG family
HUT09_23615	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HUT09_23625	COG0519	Catalyzes the synthesis of GMP from XMP
HUT09_23630	COG1024	Enoyl-CoA hydratase
HUT09_23645	COG1595	DNA-templated transcription, initiation
HUT09_23660	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT09_23695	COG0598	Magnesium transport protein CorA
HUT09_23705	COG2814	Major facilitator Superfamily
HUT09_23715	COG0613	PHP domain protein
HUT09_23720	COG2095	MarC family integral membrane protein
HUT09_23730	COG1432	Conserved Protein
HUT09_23740	COG0513	Belongs to the DEAD box helicase family
HUT09_23780	COG0747	negative chemotaxis
HUT09_23785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT09_23850	COG0210	DNA helicase
HUT09_23855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT09_23895	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HUT09_23950	COG3480	Lon protease (S16) C-terminal proteolytic domain
HUT09_23960	COG1615	UPF0182 protein
HUT09_23985	COG0753	catalase activity
HUT09_23995	COG0483	inositol monophosphate 1-phosphatase activity
HUT09_24010	COG2076	Multidrug Resistance protein
HUT09_24015	COG1162	GTPase activity
HUT09_24020	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUT09_24030	COG2135	peptidase activity
HUT09_24040	COG1595	DNA-templated transcription, initiation
HUT09_24045	COG5662	AntiSigma factor
HUT09_24065	COG0242	peptide deformylase activity
HUT09_24110	COG1966	Carbon starvation protein
HUT09_24120	COG2182	Extracellular solute-binding protein
HUT09_24125	COG1175	transmembrane transport
HUT09_24130	COG0395	ABC-type sugar transport system, permease component
HUT09_24135	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT09_24140	COG0363	glucosamine-6-phosphate deaminase activity
HUT09_24145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT09_24160	COG1597	lipid kinase activity
HUT09_24175	COG2172	sigma factor antagonist activity
HUT09_24200	COG1959	2 iron, 2 sulfur cluster binding
HUT09_24205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT09_24230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT09_24265	COG2197	response regulator
HUT09_24270	COG4585	Histidine kinase
HUT09_24305	COG4106	trans-aconitate 2-methyltransferase activity
HUT09_24310	COG1595	DNA-templated transcription, initiation
HUT09_24320	COG1126	abc transporter atp-binding protein
HUT09_24325	COG0765	amino acid transport
HUT09_24335	COG0281	malic enzyme
HUT09_24340	COG0604	alcohol dehydrogenase
HUT09_24345	COG1874	Beta-galactosidase
HUT09_24360	COG0542	response to heat
HUT09_24385	COG0567	Dehydrogenase, E1 component
HUT09_24385	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT09_24390	COG2205	protein histidine kinase activity
HUT09_24395	COG0745	RESPONSE REGULATOR receiver
HUT09_24415	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HUT09_24420	COG0726	polysaccharide deacetylase
HUT09_24425	COG1846	Transcriptional regulator
HUT09_24435	COG5002	protein histidine kinase activity
HUT09_24460	COG0791	NLP P60 protein
HUT09_24460	COG3883	PFAM NLP P60 protein
HUT09_24475	COG1309	transcriptional regulator
HUT09_24510	COG0768	penicillin binding
HUT09_24525	COG2205	protein histidine kinase activity
HUT09_24545	COG1793	dna ligase
HUT09_24545	COG3285	dna ligase
HUT09_24550	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HUT09_24565	COG3903	Transcriptional regulator
HUT09_24565	COG3629	intracellular signal transduction
HUT09_24575	COG3903	Transcriptional regulator
HUT09_24575	COG3629	intracellular signal transduction
HUT09_24595	COG0018	arginyl-trna synthetase
HUT09_24600	COG0019	diaminopimelate decarboxylase activity
HUT09_24605	COG0460	homoserine dehydrogenase
HUT09_24610	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUT09_24615	COG0083	homoserine kinase activity
HUT09_24625	COG1316	TRANSCRIPTIONal
HUT09_24630	COG0254	rRNA binding
HUT09_24635	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HUT09_24640	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT09_24650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT09_24665	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT09_24685	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUT09_24690	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HUT09_24695	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUT09_24700	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HUT09_24705	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HUT09_24710	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HUT09_24715	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HUT09_24735	COG2197	response regulator
HUT09_24755	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT09_24770	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HUT09_24825	COG0183	Belongs to the thiolase family
HUT09_24850	COG0745	RESPONSE REGULATOR receiver
HUT09_24855	COG5002	protein histidine kinase activity
HUT09_24925	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT09_24925	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT09_24930	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HUT09_24965	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HUT09_24970	COG0857	belongs to the CobB CobQ family
HUT09_24970	COG0280	phosphate acetyltransferase
HUT09_24975	COG0205	6-phosphofructokinase activity
HUT09_24985	COG4565	transcriptional regulatory protein
HUT09_24990	COG3290	protein histidine kinase activity
HUT09_24995	COG1301	dicarboxylic acid transport
HUT09_25005	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HUT09_25010	COG3281	Trehalose synthase
HUT09_25015	COG0366	Alpha amylase catalytic
HUT09_25020	COG0366	Alpha amylase catalytic
HUT09_25025	COG0058	SHG alpha-glucan phosphorylase activity
HUT09_25060	COG1132	(ABC) transporter
HUT09_25065	COG1132	(ABC) transporter
HUT09_25070	COG1131	(ABC) transporter
HUT09_25085	COG2197	response regulator
HUT09_25170	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HUT09_25180	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUT09_25185	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HUT09_25230	COG0477	Major facilitator Superfamily
HUT09_25240	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_25375	COG0823	Involved in the tonB-independent uptake of proteins
HUT09_25375	COG1506	peptidase
HUT09_25410	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_25425	COG1929	Belongs to the glycerate kinase type-1 family
HUT09_25435	COG0745	RESPONSE REGULATOR receiver
HUT09_25440	COG2205	protein histidine kinase activity
HUT09_25480	COG1760	l-serine dehydratase
HUT09_25485	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT09_25490	COG0509	glycine decarboxylation via glycine cleavage system
HUT09_25495	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HUT09_25515	COG4166	transmembrane transport
HUT09_25530	COG0444	Belongs to the ABC transporter superfamily
HUT09_25535	COG4608	Belongs to the ABC transporter superfamily
HUT09_25540	COG2860	membrane
HUT09_25575	COG0482	sulfurtransferase activity
HUT09_25595	COG4221	oxidoreductase activity
HUT09_25605	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUT09_25615	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUT09_25620	COG0154	amidase activity
HUT09_25630	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUT09_25635	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HUT09_25645	COG2409	Drug exporters of the RND superfamily
HUT09_25665	COG2133	pyrroloquinoline quinone binding
HUT09_25670	COG0667	Aldo Keto reductase
HUT09_25690	COG0440	acetolactate synthase activity
HUT09_25695	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HUT09_25700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUT09_25720	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUT09_25725	COG2508	Transcriptional regulator
HUT09_25730	COG0506	proline dehydrogenase activity
HUT09_25735	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_25740	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
HUT09_25740	COG0778	Nitroreductase
HUT09_25755	COG2130	NADP-dependent
HUT09_25760	COG0583	DNA-binding transcription factor activity
HUT09_25765	COG0473	3-isopropylmalate dehydrogenase activity
HUT09_25770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUT09_25805	COG2957	Belongs to the agmatine deiminase family
HUT09_25815	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT09_25830	COG4608	Belongs to the ABC transporter superfamily
HUT09_25835	COG0601	transmembrane transport
HUT09_25840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT09_25845	COG0444	Belongs to the ABC transporter superfamily
HUT09_25855	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT09_25875	COG2207	Transcriptional regulator
HUT09_25875	COG3708	Transcriptional regulator
HUT09_25900	COG0492	ferredoxin-NADP+ reductase activity
HUT09_25925	COG1733	regulation of RNA biosynthetic process
HUT09_25950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_25955	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_25960	COG1120	ATPase activity
HUT09_25965	COG4607	ABC-type enterochelin transport system periplasmic component
HUT09_25995	COG1470	cell adhesion involved in biofilm formation
HUT09_25995	COG0366	Alpha amylase catalytic
HUT09_26000	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT09_26020	COG2018	Roadblock/LC7 domain
HUT09_26040	COG2018	Roadblock/LC7 domain
HUT09_26045	COG5002	protein histidine kinase activity
HUT09_26055	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT09_26060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUT09_26095	COG1414	Transcriptional regulator
HUT09_26100	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HUT09_26105	COG0066	3-isopropylmalate dehydratase activity
HUT09_26115	COG0776	regulation of translation
HUT09_26125	COG1920	GTP binding
HUT09_26135	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HUT09_26140	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT09_26155	COG0351	phosphomethylpyrimidine kinase
HUT09_26160	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUT09_26165	COG1461	Dihydroxyacetone kinase
HUT09_26170	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HUT09_26175	COG0742	ribosomal rna small subunit methyltransferase
HUT09_26180	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HUT09_26195	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HUT09_26200	COG0571	ribonuclease III activity
HUT09_26205	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT09_26210	COG1733	regulation of RNA biosynthetic process
HUT09_26215	COG2340	Cysteine-rich secretory protein family
HUT09_26220	COG1254	Belongs to the acylphosphatase family
HUT09_26230	COG1196	nuclear chromosome segregation
HUT09_26235	COG0477	Major facilitator Superfamily
HUT09_26270	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HUT09_26290	COG0228	four-way junction DNA binding
HUT09_26295	COG1837	Belongs to the UPF0109 family
HUT09_26300	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HUT09_26305	COG0336	Belongs to the RNA methyltransferase TrmD family
HUT09_26310	COG0335	large ribosomal subunit rRNA binding
HUT09_26325	COG0681	Belongs to the peptidase S26 family
HUT09_26330	COG0681	Belongs to the peptidase S26 family
HUT09_26345	COG0792	nuclease activity
HUT09_26360	COG1191	sigma factor activity
HUT09_26375	COG0052	Belongs to the universal ribosomal protein uS2 family
HUT09_26380	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HUT09_26385	COG0528	UMP kinase activity
HUT09_26390	COG0233	cytoplasmic translational termination
HUT09_26400	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HUT09_26430	COG1136	(ABC) transporter
HUT09_26435	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT09_26445	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_26465	COG0584	glycerophosphoryl diester phosphodiesterase
HUT09_26470	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT09_26490	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HUT09_26495	COG3842	ATPase activity
HUT09_26500	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUT09_26505	COG1177	transmembrane transport
HUT09_26510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT09_26540	COG2508	Transcriptional regulator
HUT09_26545	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_26555	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HUT09_26560	COG0750	zinc metalloprotease
HUT09_26565	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HUT09_26580	COG0442	prolyl-tRNA aminoacylation
HUT09_26600	COG0779	Required for maturation of 30S ribosomal subunits
HUT09_26615	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HUT09_26625	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HUT09_26630	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HUT09_26665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT09_26670	COG0601	transmembrane transport
HUT09_26675	COG0747	negative chemotaxis
HUT09_26680	COG0455	bacterial-type flagellum organization
HUT09_26700	COG3266	domain, Protein
HUT09_26705	COG1404	Belongs to the peptidase S8 family
HUT09_26735	COG1674	ftsk spoiiie
HUT09_26745	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HUT09_26750	COG1185	polyribonucleotide nucleotidyltransferase activity
HUT09_26755	COG0612	Peptidase, M16
HUT09_26760	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HUT09_26780	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
HUT09_26785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT09_26790	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HUT09_26830	COG1674	ftsk spoiiie
HUT09_26840	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUT09_26850	COG1546	Belongs to the CinA family
HUT09_26850	COG1058	Belongs to the CinA family
HUT09_26855	COG1396	sequence-specific DNA binding
HUT09_26860	COG0783	Belongs to the Dps family
HUT09_26870	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_26875	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT09_26880	COG1201	RNA secondary structure unwinding
HUT09_26885	COG1917	Cupin 2, conserved barrel domain protein
HUT09_26885	COG2207	Transcriptional regulator
HUT09_26915	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_26920	COG1672	PFAM Archaeal ATPase
HUT09_26920	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT09_26930	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HUT09_26955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT09_26960	COG0765	amino acid transport
HUT09_26965	COG0765	amino acid transport
HUT09_26970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT09_26975	COG1126	abc transporter atp-binding protein
HUT09_26980	COG0745	RESPONSE REGULATOR receiver
HUT09_26985	COG2205	protein histidine kinase activity
HUT09_26990	COG2358	TRAP transporter, solute receptor (TAXI family
HUT09_26995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUT09_27010	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HUT09_27020	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HUT09_27025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUT09_27035	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUT09_27080	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HUT09_27085	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUT09_27090	COG2045	Belongs to the ComB family
HUT09_27120	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HUT09_27150	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HUT09_27155	COG2186	Transcriptional regulator
HUT09_27160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUT09_27185	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT09_27190	COG4565	transcriptional regulatory protein
HUT09_27195	COG3290	protein histidine kinase activity
HUT09_27205	COG0372	Belongs to the citrate synthase family
HUT09_27210	COG0372	Belongs to the citrate synthase family
HUT09_27220	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUT09_27225	COG0612	Peptidase, M16
HUT09_27240	COG1802	Transcriptional regulator
HUT09_27245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUT09_27250	COG1042	CoA-binding domain protein
HUT09_27250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT09_27250	COG0045	succinate-CoA ligase (ADP-forming) activity
HUT09_27265	COG1435	thymidine kinase activity
HUT09_27315	COG0745	RESPONSE REGULATOR receiver
HUT09_27320	COG2205	protein histidine kinase activity
HUT09_27345	COG0756	dUTP diphosphatase activity
HUT09_27395	COG0569	domain protein
HUT09_27400	COG0531	amino acid
HUT09_27405	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUT09_27490	COG0464	growth
HUT09_27495	COG1404	Belongs to the peptidase S8 family
HUT09_27500	COG1674	ftsk spoiiie
HUT09_27520	COG4842	Belongs to the WXG100 family
HUT09_27565	COG1309	transcriptional regulator
HUT09_27575	COG1309	transcriptional regulator
HUT09_27580	COG2814	Major facilitator Superfamily
HUT09_27590	COG4401	Chorismate mutase type I
HUT09_27595	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HUT09_27605	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_27610	COG4552	Acetyltransferase involved in intracellular survival and related
HUT09_27645	COG1309	transcriptional regulator
HUT09_27665	COG2192	nodulation
HUT09_27695	COG0505	Belongs to the CarA family
HUT09_27700	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUT09_27705	COG1280	lysine exporter protein (LysE YggA)
HUT09_27710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT09_27720	COG3291	Pkd domain containing protein
HUT09_27765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_27770	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_27800	COG0586	Pfam SNARE associated Golgi protein
HUT09_27815	COG1799	cell septum assembly
HUT09_27835	COG2040	homocysteine
HUT09_27845	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUT09_27855	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUT09_27860	COG0531	amino acid
HUT09_27870	COG1024	Enoyl-CoA hydratase
HUT09_27905	COG3592	Divergent 4Fe-4S mono-cluster
HUT09_27910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUT09_27910	COG2111	Na H antiporter
HUT09_27935	COG1320	monovalent cation:proton antiporter activity
HUT09_27950	COG0297	glycogen (starch) synthase activity
HUT09_27955	COG0489	protein tyrosine kinase activity
HUT09_27995	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HUT09_28000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT09_28005	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HUT09_28035	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUT09_28045	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUT09_28045	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUT09_28075	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_28080	COG2046	Belongs to the sulfate adenylyltransferase family
HUT09_28080	COG0529	Catalyzes the synthesis of activated sulfate
HUT09_28095	COG3903	Transcriptional regulator
HUT09_28095	COG3629	intracellular signal transduction
HUT09_28110	COG0697	spore germination
HUT09_28115	COG2814	Major facilitator Superfamily
HUT09_28120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUT09_28145	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HUT09_28155	COG0406	alpha-ribazole phosphatase activity
HUT09_28165	COG1653	transport
HUT09_28170	COG1175	transmembrane transport
HUT09_28175	COG0395	ABC-type sugar transport system, permease component
HUT09_28180	COG1940	carbohydrate kinase activity
HUT09_28185	COG4213	ABC transporter substrate-binding protein
HUT09_28195	COG4214	carbohydrate transport
HUT09_28200	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUT09_28205	COG0531	amino acid
HUT09_28215	COG1316	TRANSCRIPTIONal
HUT09_28225	COG0438	transferase activity, transferring glycosyl groups
HUT09_28230	COG0438	transferase activity, transferring glycosyl groups
HUT09_28240	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HUT09_28245	COG0438	transferase activity, transferring glycosyl groups
HUT09_28250	COG1024	Enoyl-CoA hydratase
HUT09_28250	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT09_28255	COG0183	Belongs to the thiolase family
HUT09_28275	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HUT09_28280	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT09_28310	COG3220	belongs to the UPF0276 family
HUT09_28390	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUT09_28395	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUT09_28450	COG0483	inositol monophosphate 1-phosphatase activity
HUT09_28460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT09_28475	COG1063	alcohol dehydrogenase
HUT09_28480	COG0156	8-amino-7-oxononanoate synthase activity
HUT09_28485	COG0583	DNA-binding transcription factor activity
HUT09_28495	COG0346	lactoylglutathione lyase activity
HUT09_28500	COG1072	(Pantothenic acid kinase))
HUT09_28515	COG2723	6-phospho-beta-galactosidase activity
HUT09_28570	COG1175	transmembrane transport
HUT09_28590	COG1404	Belongs to the peptidase S8 family
HUT09_28605	COG0596	Alpha beta hydrolase
HUT09_28615	COG1132	(ABC) transporter
HUT09_28620	COG1132	(ABC) transporter
HUT09_28625	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HUT09_28635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT09_28640	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HUT09_28660	COG0529	Catalyzes the synthesis of activated sulfate
HUT09_28665	COG0175	sulfate reduction
HUT09_28690	COG1960	acyl-CoA dehydrogenase activity
HUT09_28710	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT09_28715	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUT09_28720	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HUT09_28725	COG0583	DNA-binding transcription factor activity
HUT09_28730	COG0183	Belongs to the thiolase family
HUT09_28775	COG1162	GTPase activity
HUT09_28800	COG0028	Belongs to the TPP enzyme family
HUT09_28825	COG1802	Transcriptional regulator
HUT09_28850	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT09_28855	COG2252	PERMEase
HUT09_28860	COG3608	succinylglutamate desuccinylase aspartoacylase
HUT09_28860	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HUT09_28930	COG0435	Glutathione S-transferase
HUT09_28945	COG2197	response regulator
HUT09_28950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT09_28955	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_28975	COG3960	tartronate-semialdehyde synthase activity
HUT09_28990	COG3903	Transcriptional regulator
HUT09_28990	COG3629	intracellular signal transduction
HUT09_29000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT09_29010	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT09_29020	COG0436	Aminotransferase
HUT09_29025	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HUT09_29040	COG0753	catalase activity
HUT09_29045	COG2084	Dehydrogenase
HUT09_29050	COG3622	Belongs to the hyi family
HUT09_29065	COG0395	ABC-type sugar transport system, permease component
HUT09_29070	COG1175	transmembrane transport
HUT09_29080	COG2188	Transcriptional regulator
HUT09_29085	COG2706	6-phosphogluconolactonase activity
HUT09_29105	COG2351	hydroxyisourate hydrolase activity
HUT09_29115	COG2233	PERMEase
HUT09_29125	COG2233	PERMEase
HUT09_29135	COG0596	Alpha beta hydrolase
HUT09_29160	COG1288	antiporter activity
HUT09_29165	COG1733	regulation of RNA biosynthetic process
HUT09_29200	COG2197	response regulator
HUT09_29220	COG1414	Transcriptional regulator
HUT09_29225	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT09_29230	COG4266	Belongs to the allantoicase family
HUT09_29235	COG0656	L-ascorbic acid biosynthetic process
HUT09_29240	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_29265	COG2197	response regulator
HUT09_29280	COG0673	inositol 2-dehydrogenase activity
HUT09_29285	COG2188	Transcriptional regulator
HUT09_29300	COG1129	ABC transporter
HUT09_29305	COG1940	carbohydrate kinase activity
HUT09_29315	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT09_29320	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HUT09_29335	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_29360	COG1126	abc transporter atp-binding protein
HUT09_29365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT09_29370	COG0765	amino acid transport
HUT09_29375	COG0765	amino acid transport
HUT09_29395	COG0367	asparagine synthase
HUT09_29400	COG0477	Major facilitator Superfamily
HUT09_29415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT09_29430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT09_29435	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_29445	COG0405	Gamma-glutamyltransferase
HUT09_29475	COG0667	Aldo Keto reductase
HUT09_29490	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT09_29510	COG1953	Uracil, thiamine, allantoin
HUT09_29560	COG0095	Lipoate-protein ligase
HUT09_29570	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HUT09_29580	COG3800	Transcriptional regulator
HUT09_29580	COG1396	sequence-specific DNA binding
HUT09_29600	COG1960	acyl-CoA dehydrogenase activity
HUT09_29635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT09_29650	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HUT09_29665	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HUT09_29705	COG1024	Enoyl-CoA hydratase
HUT09_29710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT09_29725	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_29745	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_29750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT09_29755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT09_29765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT09_29775	COG1131	(ABC) transporter
HUT09_29780	COG1024	Enoyl-CoA hydratase
HUT09_29810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUT09_29825	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUT09_29840	COG1929	Belongs to the glycerate kinase type-1 family
HUT09_29860	COG0559	Belongs to the binding-protein-dependent transport system permease family
HUT09_29910	COG0688	phosphatidylethanolamine metabolic process
HUT09_29915	COG1960	acyl-CoA dehydrogenase activity
HUT09_29925	COG2301	Belongs to the HpcH HpaI aldolase family
HUT09_29930	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT09_29930	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT09_29935	COG0604	alcohol dehydrogenase
HUT09_29955	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT09_29985	COG0583	DNA-binding transcription factor activity
HUT09_29990	COG0667	Aldo Keto reductase
HUT09_30000	COG2362	D-Aminopeptidase
HUT09_30005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT09_30015	COG1619	proteins homologs of microcin C7 resistance protein MccF
HUT09_30030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT09_30045	COG2226	methyltransferase
HUT09_30065	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HUT09_30090	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUT09_30105	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT09_30105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT09_30115	COG2154	pterin-4-alpha-carbinolamine dehydratase
HUT09_30135	COG4106	trans-aconitate 2-methyltransferase activity
HUT09_30145	COG0656	L-ascorbic acid biosynthetic process
HUT09_30155	COG0583	DNA-binding transcription factor activity
HUT09_30170	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HUT09_30175	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT09_30185	COG1129	ABC transporter
HUT09_30190	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT09_30195	COG1879	ABC-type sugar transport system periplasmic component
HUT09_30200	COG0673	inositol 2-dehydrogenase activity
HUT09_30220	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HUT09_30285	COG1129	ABC transporter
HUT09_30295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT09_30300	COG1869	D-ribose catabolic process
HUT09_30310	COG0714	Associated with various cellular activities
HUT09_30340	COG5000	phosphorelay sensor kinase activity
HUT09_30340	COG5002	protein histidine kinase activity
HUT09_30345	COG0745	RESPONSE REGULATOR receiver
HUT09_30370	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_30380	COG0517	IMP dehydrogenase activity
HUT09_30380	COG4175	Glycine betaine
HUT09_30385	COG4176	ABC-type proline glycine betaine transport system permease component
HUT09_30405	COG0569	domain protein
HUT09_30405	COG2985	domain, Protein
HUT09_30420	COG1070	Carbohydrate kinase
HUT09_30430	COG1940	carbohydrate kinase activity
HUT09_30455	COG1289	transmembrane transporter activity
HUT09_30460	COG1846	Transcriptional regulator
HUT09_30490	COG2124	cytochrome p450
HUT09_30495	COG1486	melibiose metabolic process
HUT09_30535	COG3012	SEC-C Motif Domain Protein
HUT09_30580	COG1127	ABC transporter
HUT09_30590	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUT09_30615	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HUT09_30650	COG2770	Histidine kinase
HUT09_30650	COG2208	phosphoserine phosphatase activity
HUT09_30670	COG2326	polyphosphate kinase activity
HUT09_30675	COG1793	dna ligase
HUT09_30705	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUT09_30725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT09_30730	COG1116	anion transmembrane transporter activity
HUT09_30735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUT09_30740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_30760	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT09_30765	COG0488	(ABC) transporter
HUT09_30780	COG1515	deoxyribonuclease V activity
HUT09_30790	COG3268	Saccharopine dehydrogenase
HUT09_30800	COG1960	acyl-CoA dehydrogenase activity
HUT09_30805	COG0183	Belongs to the thiolase family
HUT09_30810	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT09_30810	COG1024	Enoyl-CoA hydratase
HUT09_30815	COG0789	Transcriptional regulator
HUT09_30840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUT09_30850	COG0488	(ABC) transporter
HUT09_30855	COG2183	response to ionizing radiation
HUT09_30865	COG4977	sequence-specific DNA binding
HUT09_30875	COG1024	Enoyl-CoA hydratase
HUT09_30890	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HUT09_30920	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HUT09_30940	COG1134	teichoic acid transport
HUT09_30945	COG1562	ergosterol biosynthetic process
HUT09_30955	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HUT09_30965	COG1657	PFAM Prenyltransferase squalene oxidase
HUT09_31000	COG0739	heme binding
HUT09_31005	COG2755	lipolytic protein G-D-S-L family
HUT09_31055	COG3467	pyridoxamine 5'-phosphate
HUT09_31095	COG1609	Transcriptional regulator
HUT09_31100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT09_31110	COG1116	anion transmembrane transporter activity
HUT09_31140	COG3958	Transketolase
HUT09_31145	COG3959	Transketolase, thiamine diphosphate binding domain
HUT09_31190	COG2226	methyltransferase
HUT09_31195	COG1132	(ABC) transporter
HUT09_31255	COG0542	response to heat
HUT09_31275	COG3511	phospholipase C
HUT09_31285	COG2197	response regulator
HUT09_31290	COG3851	Histidine kinase
HUT09_31300	COG2186	Transcriptional regulator
HUT09_31305	COG0247	lactate metabolic process
HUT09_31310	COG1139	Iron-sulfur cluster binding protein
HUT09_31315	COG1556	Lactate utilization protein
HUT09_31335	COG1672	PFAM Archaeal ATPase
HUT09_31335	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT09_31345	COG3046	protein related to deoxyribodipyrimidine photolyase
HUT09_31350	COG1533	DNA photolyase activity
HUT09_31415	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT09_31415	COG1902	pentaerythritol trinitrate reductase activity
HUT09_31430	COG2409	Drug exporters of the RND superfamily
HUT09_31435	COG1846	Transcriptional regulator
HUT09_31495	COG1233	COG1233 Phytoene dehydrogenase and related
HUT09_31500	COG2130	NADP-dependent
HUT09_31525	COG2837	iron assimilation
HUT09_31530	COG0672	)-iron permease
HUT09_31535	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HUT09_31550	COG1051	belongs to the nudix hydrolase family
HUT09_31565	COG0019	diaminopimelate decarboxylase activity
HUT09_31575	COG2837	iron assimilation
HUT09_31580	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HUT09_31595	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HUT09_31600	COG2272	Belongs to the type-B carboxylesterase lipase family
HUT09_31605	COG0789	Transcriptional regulator
HUT09_31645	COG2723	6-phospho-beta-galactosidase activity
HUT09_31650	COG0395	ABC-type sugar transport system, permease component
HUT09_31655	COG1175	transmembrane transport
HUT09_31665	COG1940	carbohydrate kinase activity
HUT09_31675	COG1652	LysM domain
HUT09_31710	COG0784	Response regulator, receiver
HUT09_31715	COG4251	negative regulation of phosphorylation
HUT09_31720	COG2201	protein-glutamate methylesterase activity
HUT09_31725	COG1191	sigma factor activity
HUT09_31770	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT09_31790	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT09_31795	COG3275	phosphorelay sensor kinase activity
HUT09_31870	COG0583	DNA-binding transcription factor activity
HUT09_31880	COG1053	succinate dehydrogenase
HUT09_31885	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUT09_31895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_31905	COG3360	Dodecin
HUT09_31910	COG2182	Extracellular solute-binding protein
HUT09_31925	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
HUT09_31930	COG0121	glutamine amidotransferase
HUT09_31935	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUT09_31940	COG3572	ergothioneine biosynthetic process
HUT09_31960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT09_31965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUT09_31970	COG2066	Belongs to the glutaminase family
HUT09_31975	COG0297	glycogen (starch) synthase activity
HUT09_31980	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HUT09_31990	COG0477	Major facilitator Superfamily
HUT09_32000	COG3693	PFAM glycoside hydrolase, family 10
HUT09_32035	COG0300	oxidoreductase activity
HUT09_32040	COG2207	Transcriptional regulator
HUT09_32070	COG1834	amidinotransferase
HUT09_32085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUT09_32125	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_32170	COG2207	Transcriptional regulator
HUT09_32175	COG2223	nitrite transmembrane transporter activity
HUT09_32200	COG0747	negative chemotaxis
HUT09_32205	COG0601	transmembrane transport
HUT09_32210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT09_32215	COG0444	Belongs to the ABC transporter superfamily
HUT09_32220	COG4608	Belongs to the ABC transporter superfamily
HUT09_32225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT09_32230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT09_32240	COG0431	NADPH-dependent FMN reductase
HUT09_32260	COG1609	Transcriptional regulator
HUT09_32275	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT09_32280	COG1129	ABC transporter
HUT09_32290	COG3347	Dehydrogenase
HUT09_32290	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_32295	COG1070	Carbohydrate kinase
HUT09_32300	COG3250	beta-galactosidase activity
HUT09_32315	COG1120	ATPase activity
HUT09_32330	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUT09_32340	COG0254	rRNA binding
HUT09_32345	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUT09_32350	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUT09_32355	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUT09_32375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_32380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT09_32385	COG1120	ATPase activity
HUT09_32415	COG1132	(ABC) transporter
HUT09_32460	COG0438	transferase activity, transferring glycosyl groups
HUT09_32510	COG1174	glycine betaine transport
HUT09_32515	COG1174	glycine betaine transport
HUT09_32530	COG0517	IMP dehydrogenase activity
HUT09_32530	COG1125	glycine betaine transport
HUT09_32540	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUT09_32560	COG1960	acyl-CoA dehydrogenase activity
HUT09_32565	COG1960	acyl-CoA dehydrogenase activity
HUT09_32580	COG0601	transmembrane transport
HUT09_32585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT09_32590	COG0444	Belongs to the ABC transporter superfamily
HUT09_32655	COG1796	DNA polymerase
HUT09_32655	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HUT09_32745	COG1278	Cold shock
HUT09_32760	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT09_32765	COG0693	protein deglycase activity
HUT09_32795	COG2267	carboxylic ester hydrolase activity
HUT09_32800	COG4044	May play a role in the intracellular transport of hydrophobic ligands
HUT09_32845	COG5297	Belongs to the glycosyl hydrolase family 6
HUT09_32850	COG2175	clavaminate synthase activity
HUT09_32915	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HUT09_32935	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_32955	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUT09_32960	COG3239	Fatty acid desaturase
HUT09_33000	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT09_33010	COG0640	Transcriptional regulator
HUT09_33025	COG2018	Roadblock/LC7 domain
HUT09_33050	COG1024	Enoyl-CoA hydratase
HUT09_33090	COG1595	DNA-templated transcription, initiation
HUT09_33105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUT09_33110	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUT09_33125	COG2340	Cysteine-rich secretory protein family
HUT09_33155	COG0583	DNA-binding transcription factor activity
HUT09_33175	COG0488	(ABC) transporter
HUT09_33200	COG0009	L-threonylcarbamoyladenylate synthase
HUT09_33255	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
HUT09_33295	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT09_33310	COG1891	lyase activity
HUT09_33320	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT09_33345	COG2318	DinB family
HUT09_33370	COG0395	ABC-type sugar transport system, permease component
HUT09_33375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUT09_33380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT09_33390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT09_33415	COG0583	DNA-binding transcription factor activity
HUT09_33420	COG2367	Beta-lactamase
HUT09_33485	COG4221	oxidoreductase activity
HUT09_33490	COG0596	Alpha beta hydrolase
HUT09_33520	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT09_33525	COG0318	PFAM AMP-dependent synthetase and ligase
HUT09_33540	COG0477	Major facilitator Superfamily
HUT09_33560	COG1012	belongs to the aldehyde dehydrogenase family
HUT09_33585	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUT09_33595	COG3548	integral membrane protein
HUT09_33605	COG1191	sigma factor activity
HUT09_33650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT09_33680	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT09_33685	COG2208	phosphoserine phosphatase activity
HUT09_33685	COG2770	Histidine kinase
HUT09_33715	COG0456	acetyltransferase
HUT09_33730	COG0640	Transcriptional regulator
HUT09_33765	COG1120	ATPase activity
HUT09_33770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUT09_33810	COG3385	transposase activity
HUT09_33855	COG0105	UTP biosynthetic process
HUT09_34000	COG4974	Belongs to the 'phage' integrase family
HUT09_34050	COG1191	sigma factor activity
HUT09_34215	COG0659	secondary active sulfate transmembrane transporter activity
HUT09_34225	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HUT09_34345	COG3848	Pyruvate phosphate dikinase
HUT09_34345	COG0574	Belongs to the PEP-utilizing enzyme family
HUT09_34360	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HUT09_34365	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HUT09_34370	COG2226	methyltransferase
HUT09_34425	COG3385	transposase activity
HUT09_34465	COG2124	cytochrome p450
HUT09_34505	COG0438	transferase activity, transferring glycosyl groups
HUT09_34520	COG2226	methyltransferase
HUT09_34535	COG0656	L-ascorbic acid biosynthetic process
HUT09_34600	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_34620	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT09_34670	COG0531	amino acid
HUT09_34695	COG2409	Drug exporters of the RND superfamily
HUT09_34700	COG4585	Histidine kinase
HUT09_34705	COG2197	response regulator
HUT09_34770	COG1482	cell wall glycoprotein biosynthetic process
HUT09_34790	COG0395	ABC-type sugar transport system, permease component
HUT09_34795	COG1175	transmembrane transport
HUT09_34890	COG1191	sigma factor activity
HUT09_34910	COG3903	Transcriptional regulator
HUT09_34910	COG3629	intracellular signal transduction
HUT09_34950	COG0069	glutamate synthase activity
HUT09_34960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUT09_34980	COG0596	Alpha beta hydrolase
HUT09_34990	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT09_35000	COG1191	sigma factor activity
HUT09_35020	COG2172	sigma factor antagonist activity
HUT09_35030	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT09_35075	COG1278	Cold shock
HUT09_35080	COG0513	Belongs to the DEAD box helicase family
HUT09_35190	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUT09_35215	COG0583	DNA-binding transcription factor activity
HUT09_35220	COG2814	Major facilitator Superfamily
HUT09_35235	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HUT09_35245	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUT09_35250	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUT09_35255	COG0367	asparagine synthase
HUT09_35270	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUT09_35290	COG1132	(ABC) transporter
HUT09_35330	COG1960	acyl-CoA dehydrogenase activity
HUT09_35335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT09_35345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT09_35430	COG2963	transposase activity
HUT09_35470	COG0463	Glycosyl transferase, family 2
HUT09_35525	COG3328	transposase activity
HUT09_35530	COG2382	esterase
HUT09_35530	COG3693	PFAM glycoside hydrolase, family 10
HUT09_35530	COG3507	Belongs to the glycosyl hydrolase 43 family
HUT09_35550	COG3291	Pkd domain containing protein
HUT09_35555	COG4608	Belongs to the ABC transporter superfamily
HUT09_35565	COG0601	transmembrane transport
HUT09_35575	COG0747	negative chemotaxis
HUT09_35580	COG0006	proline dipeptidase activity
HUT09_35585	COG1802	Transcriptional regulator
HUT09_35590	COG2423	ornithine cyclodeaminase activity
HUT09_35595	COG3938	Belongs to the proline racemase family
HUT09_35600	COG3938	Belongs to the proline racemase family
HUT09_35610	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT09_35620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT09_35695	COG2319	Wd-40 repeat
HUT09_35695	COG4249	Peptidase C14 caspase catalytic subunit p20
HUT09_35785	COG0667	Aldo Keto reductase
HUT09_35805	COG0300	oxidoreductase activity
HUT09_35835	COG3251	PFAM MbtH domain protein
HUT09_35870	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HUT09_35880	COG2801	Transposase and inactivated derivatives
HUT09_35895	COG3629	intracellular signal transduction
HUT09_35895	COG3903	Transcriptional regulator
HUT09_35955	COG0259	pyridoxamine-phosphate oxidase activity
HUT09_36000	COG0443	Heat shock 70 kDa protein
HUT09_36060	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HUT09_36065	COG1518	maintenance of DNA repeat elements
HUT09_36215	COG0667	Aldo Keto reductase
HUT09_36270	COG1335	isochorismatase
HUT09_36290	COG2814	Major facilitator Superfamily
HUT09_36395	COG1192	Involved in chromosome partitioning
HUT09_36425	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUT09_36435	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
HUT09_36450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUT09_36455	COG0587	DNA-directed DNA polymerase activity
HUT09_36470	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HUT09_36580	COG2770	Histidine kinase
HUT09_36580	COG2208	phosphoserine phosphatase activity
HUT09_36635	COG3547	Transposase (IS116 IS110 IS902 family)
HUT09_36650	COG5297	Belongs to the glycosyl hydrolase family 6
HUT09_36650	COG4733	cellulase activity
HUT09_36695	COG0656	L-ascorbic acid biosynthetic process
HUT09_36705	COG1733	regulation of RNA biosynthetic process
HUT09_36835	COG1028	Short-chain dehydrogenase reductase Sdr
HUT09_36840	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUT09_36895	COG0659	secondary active sulfate transmembrane transporter activity
HUT09_36905	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HUT09_36960	COG0305	Participates in initiation and elongation during chromosome replication
HUT09_37030	COG1475	DNA binding
HUT09_37135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair