locus-tag	class	description
HZZ00_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HZZ00_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HZZ00_00015	ENOG4108J5G	6-phosphogluconate dehydrogenase
HZZ00_00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HZZ00_00025	ENOG4105K7N	UPF0232 protein
HZZ00_00030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HZZ00_00035	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HZZ00_00065	ENOG4108HMN	Caspase domain
HZZ00_00095	ENOG4108UGD	Serine Threonine protein kinase
HZZ00_00140	ENOG4105ZJT	Cell division protein CrgA
HZZ00_00160	ENOG4108U4N	(sortase) family
HZZ00_00165	ENOG4108RN7	integral membrane protein
HZZ00_00190	ENOG4105HZM	Fha domain containing protein
HZZ00_00195	ENOG4105TV9	FHA Domain-Containing protein
HZZ00_00230	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HZZ00_00235	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
HZZ00_00240	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
HZZ00_00245	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
HZZ00_00250	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
HZZ00_00275	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HZZ00_00280	ENOG4108IG5	Transcriptional regulator
HZZ00_00300	ENOG4107QSN	dihydrolipoamide acetyltransferase
HZZ00_00315	ENOG4107SVH	Potassium channel protein
HZZ00_00335	ENOG4107QPV	Serine Threonine protein kinase
HZZ00_00355	ENOG4105CPP	Dehydrogenase, E1 component
HZZ00_00360	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
HZZ00_00430	ENOG4105DJB	Major Facilitator Superfamily
HZZ00_00465	ENOG4105DFM	M18 family aminopeptidase
HZZ00_00470	ENOG4105CSU	acyl-Coa dehydrogenase
HZZ00_00480	ENOG4105EUB	pirin domain protein
HZZ00_00495	ENOG4105C9M	aspartyl-trna synthetase
HZZ00_00505	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HZZ00_00515	ENOG4105F2Z	3-oxoadipate enol-lactonase
HZZ00_00520	ENOG4107U9B	transcriptional regulator
HZZ00_00545	ENOG4105CH2	amidohydrolase
HZZ00_00565	ENOG4105C22	threonyL-tRNA synthetase
HZZ00_00570	ENOG4105DU0	nucleoside hydrolase
HZZ00_00575	ENOG4105CG3	alpha amylase, catalytic region
HZZ00_00590	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HZZ00_00640	ENOG4108M4U	conserved membrane protein
HZZ00_00665	ENOG4105FDP	GntR family transcriptional regulator
HZZ00_00675	ENOG4108KPJ	rna polymerase sigma factor
HZZ00_00700	ENOG41082SX	arsR family transcriptional regulator
HZZ00_00705	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HZZ00_00720	ENOG4108Z4X	TRANSCRIPTIONal
HZZ00_00725	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HZZ00_00735	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
HZZ00_00745	ENOG4105C1J	atp-dependent rna helicase
HZZ00_00750	ENOG4105VEQ	Cold shock protein
HZZ00_00770	ENOG4105C1J	atp-dependent rna helicase
HZZ00_00775	ENOG4105VEQ	Cold shock protein
HZZ00_00805	ENOG4108762	serine threonine protein kinase
HZZ00_00815	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HZZ00_00820	ENOG4108IND	Tetr family transcriptional regulator
HZZ00_00830	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HZZ00_00840	ENOG41090G8	Toxic component of a toxin-antitoxin (TA) module. A
HZZ00_00855	ENOG4105DHP	deoxycytidine triphosphate deaminase
HZZ00_00860	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
HZZ00_00880	ENOG4105DF6	Fe-S oxidoreductase
HZZ00_00890	ENOG4105CFG	Acts as a chaperone (By similarity)
HZZ00_00895	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HZZ00_00900	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HZZ00_00905	ENOG4105KNI	merR family transcriptional Regulator
HZZ00_00910	ENOG4105DFW	ABC transporter
HZZ00_00945	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HZZ00_00970	ENOG4108E19	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HZZ00_00985	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HZZ00_01010	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
HZZ00_01030	ENOG4108ZGX	Histidine kinase
HZZ00_01035	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_01040	ENOG4105BZU	Histidine kinase
HZZ00_01045	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_01060	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HZZ00_01065	ENOG4105CGH	5'-nucleotidase
HZZ00_01075	ENOG4108WYP	Transcriptional regulator
HZZ00_01080	ENOG4108JPW	Aminotransferase
HZZ00_01085	ENOG4108762	serine threonine protein kinase
HZZ00_01100	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HZZ00_01105	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HZZ00_01115	ENOG4105CFH	Aspartokinase
HZZ00_01125	ENOG4105NAF	rna polymerase sigma factor
HZZ00_01150	ENOG4105ZXU	NLP P60 protein
HZZ00_01160	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HZZ00_01165	ENOG4108YZJ	Pfam:DUF2596
HZZ00_01190	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HZZ00_01235	ENOG4105BZU	Histidine kinase
HZZ00_01250	ENOG4108VJ1	Transcriptional regulator (CarD family
HZZ00_01255	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HZZ00_01260	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HZZ00_01270	ENOG4105C8N	cysteinyl-tRNA synthetase
HZZ00_01285	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HZZ00_01315	ENOG4105CPC	Aldo Keto reductase
HZZ00_01335	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HZZ00_01340	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HZZ00_01350	ENOG4108WAV	Transcriptional regulator
HZZ00_01365	ENOG4105GCH	Cupin 2 Conserved Barrel Domain Protein
HZZ00_01375	ENOG4108PDG	Beta-ketoacyl synthase
HZZ00_01380	ENOG41079R3	acyl carrier protein
HZZ00_01385	ENOG4108Y5I	Cyclase dehydrase
HZZ00_01390	ENOG4105KTE	polyketide synthesis cyclase
HZZ00_01450	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
HZZ00_01470	ENOG4105BZU	Histidine kinase
HZZ00_01485	ENOG4105CE4	GlcNAc 6-P deacetylase
HZZ00_01490	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
HZZ00_01515	ENOG4105C3Q	Glycosyl transferase, family 2
HZZ00_01530	ENOG4105VEQ	Cold shock protein
HZZ00_01535	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HZZ00_01550	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HZZ00_01555	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HZZ00_01560	ENOG4105QEK	Transcriptional regulator
HZZ00_01590	ENOG4106N3A	copper homeostasis protein cutc
HZZ00_01595	ENOG4105DZ6	Band 7 protein
HZZ00_01605	ENOG4105EEM	helicase
HZZ00_01645	ENOG4105VEQ	Cold shock protein
HZZ00_01650	ENOG4105E63	Pfam:DUF178
HZZ00_01655	ENOG4108UIH	futalosine nucleosidase
HZZ00_01665	ENOG4108N0W	Major Facilitator superfamily
HZZ00_01695	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HZZ00_01705	ENOG4105C7N	Xanthine uracil vitamin C permease
HZZ00_01735	ENOG4105CPC	Aldo Keto reductase
HZZ00_01750	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HZZ00_01755	ENOG4105CQB	FAD linked oxidase domain protein
HZZ00_01765	ENOG4107AQZ	Membrane
HZZ00_01785	ENOG4107QX3	carboxylase
HZZ00_01805	ENOG4108IG5	Transcriptional regulator
HZZ00_01820	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HZZ00_01835	ENOG4108SU4	UPF0309 protein
HZZ00_01845	ENOG4108XEP	Alpha Beta Hydrolase Fold protein
HZZ00_01895	ENOG4105WN5	stage II sporulation protein
HZZ00_01915	ENOG4105ECQ	AraC Family Transcriptional Regulator
HZZ00_01920	ENOG4105D2S	major facilitator superfamily
HZZ00_01925	ENOG4105H3G	oxidoreductase
HZZ00_01935	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HZZ00_01940	ENOG4105N14	lysine exporter protein LysE YggA
HZZ00_01945	ENOG4105F7P	transcriptional regulator AsnC family
HZZ00_01960	ENOG4108762	serine threonine protein kinase
HZZ00_02010	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
HZZ00_02095	ENOG4108V06	Glutathione peroxidase
HZZ00_02120	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HZZ00_02135	ENOG4108YV4	Universal stress protein
HZZ00_02170	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HZZ00_02185	ENOG41064MX	Tetr family transcriptional regulator
HZZ00_02255	ENOG4105FP9	thiamine pyrophosphate
HZZ00_02265	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
HZZ00_02270	ENOG4105CG3	alpha amylase, catalytic region
HZZ00_02290	ENOG4108IG5	Transcriptional regulator
HZZ00_02315	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HZZ00_02320	ENOG4108Z7F	N-acetyltransferase
HZZ00_02350	ENOG4107UBC	ErfK ybiS ycfS ynhG family protein
HZZ00_02370	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HZZ00_02380	ENOG4107USC	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
HZZ00_02395	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
HZZ00_02400	ENOG4105CUJ	penicillin amidase
HZZ00_02405	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
HZZ00_02410	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HZZ00_02420	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HZZ00_02425	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HZZ00_02430	ENOG4105D9U	N-acetyltransferase
HZZ00_02445	ENOG4105VEV	-acetyltransferase
HZZ00_02460	ENOG4105F95	Monooxygenase
HZZ00_02470	ENOG4108BAS	reductase
HZZ00_02490	ENOG4105EYF	MMPL domain protein
HZZ00_02495	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HZZ00_02500	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HZZ00_02515	ENOG4108JJB	ABC transporter
HZZ00_02525	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
HZZ00_02575	ENOG4105F8V	Hydrolase, tatD family
HZZ00_02585	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HZZ00_02590	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HZZ00_02595	ENOG4105C5H	ABC transporter
HZZ00_02635	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HZZ00_02645	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_02650	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
HZZ00_02655	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HZZ00_02665	ENOG41067SE	Tetr family transcriptional regulator
HZZ00_02675	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HZZ00_02685	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HZZ00_02690	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HZZ00_02695	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HZZ00_02700	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HZZ00_02710	ENOG4105BZU	Histidine kinase
HZZ00_02740	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HZZ00_02745	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HZZ00_02805	ENOG4106A3M	Cytochrome p-450
HZZ00_02820	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HZZ00_02840	ENOG4105CEP	NADH dehydrogenase
HZZ00_02845	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HZZ00_02850	ENOG4107RBB	ABC transporter, permease
HZZ00_02855	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HZZ00_02885	ENOG4105CHU	acetyl-coa acetyltransferase
HZZ00_02955	ENOG4105CGP	Urocanate hydratase
HZZ00_02970	ENOG4105CI2	imidazolone-5-propionate hydrolase
HZZ00_02975	ENOG4108N6D	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HZZ00_02980	ENOG41082AN	stage II sporulation protein
HZZ00_02990	ENOG4105DUX	Transporter
HZZ00_02995	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HZZ00_03000	ENOG41065SU	Two-component system sensor kinase
HZZ00_03040	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HZZ00_03055	ENOG4108KQ5	Integrase catalytic subunit
HZZ00_03060	ENOG4108KGH	TRANSCRIPTIONal
HZZ00_03065	ENOG4108S4H	thioesterase Superfamily protein
HZZ00_03080	ENOG4108KGH	TRANSCRIPTIONal
HZZ00_03085	ENOG4108KGH	TRANSCRIPTIONal
HZZ00_03100	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
HZZ00_03110	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
HZZ00_03125	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
HZZ00_03130	ENOG4107RGC	Glycosyl transferase, family 2
HZZ00_03155	ENOG4105W49	UPF0434 protein
HZZ00_03165	ENOG4105EIP	mannose-6-phosphate isomerase
HZZ00_03175	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HZZ00_03215	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HZZ00_03220	ENOG4108WQ6	secreted protein
HZZ00_03235	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
HZZ00_03240	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HZZ00_03245	ENOG4105BZU	Histidine kinase
HZZ00_03250	ENOG4105G3P	Lipoprotein lpqB
HZZ00_03260	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
HZZ00_03265	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_03270	ENOG4105T0Z	Conserved Protein
HZZ00_03280	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HZZ00_03305	ENOG4105C7I	Dehydrogenase
HZZ00_03320	ENOG4107SJB	teichoic acid biosynthesis
HZZ00_03325	ENOG4105EY8	ABC transporter
HZZ00_03345	ENOG4105CMR	udp-glucose 4-epimerase
HZZ00_03365	ENOG4105K56	Transcriptional regulator
HZZ00_03370	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HZZ00_03375	ENOG4105K64	Glycosyl transferase, family 2
HZZ00_03380	ENOG4107SJB	teichoic acid biosynthesis
HZZ00_03385	ENOG4105K64	Glycosyl transferase, family 2
HZZ00_03390	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
HZZ00_03400	ENOG4108JP0	extracellular solute-binding protein family 1
HZZ00_03405	ENOG4105EC2	ftsk spoIIIe
HZZ00_03410	ENOG4108UGD	Serine Threonine protein kinase
HZZ00_03415	ENOG4108QVN	serine threonine protein kinase
HZZ00_03420	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
HZZ00_03435	ENOG4105CAK	Cell division ATP-binding protein ftsE
HZZ00_03440	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
HZZ00_03445	ENOG4105CN1	protease
HZZ00_03450	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HZZ00_03465	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HZZ00_03475	ENOG4105EEM	helicase
HZZ00_03485	ENOG4108426	dNA-binding protein
HZZ00_03490	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HZZ00_03495	ENOG4108UJU	UPF0301 protein
HZZ00_03505	ENOG4105E2D	ec 3.2.1.52
HZZ00_03565	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
HZZ00_03575	ENOG4105CQB	FAD linked oxidase domain protein
HZZ00_03580	ENOG4105KF0	sporulation and cell division protein, SsgA
HZZ00_03610	ENOG4108RWI	nicotinamidase
HZZ00_03620	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HZZ00_03630	ENOG4105C85	amino acid
HZZ00_03665	ENOG4108RQ5	Beta-lactamase domain-containing protein
HZZ00_03685	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HZZ00_03700	ENOG4108IUW	ABC transporter
HZZ00_03715	ENOG4105BZ4	penicillin-binding protein
HZZ00_03745	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HZZ00_03755	ENOG4106BRA	Membrane
HZZ00_03760	ENOG4107QNK	)-transporter
HZZ00_03765	ENOG4105KVH	Transcriptional regulator
HZZ00_03775	ENOG41087EV	Hsp20/alpha crystallin family
HZZ00_03785	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HZZ00_03895	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HZZ00_03910	ENOG41090KN	UPF0303 protein
HZZ00_03915	ENOG4105D9R	oxidoreductase
HZZ00_03920	ENOG4105E2R	ROK family
HZZ00_03940	ENOG41080U6	GntR family transcriptional regulator
HZZ00_03955	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HZZ00_03965	ENOG4108N53	binding-protein-dependent transport systems inner membrane Component
HZZ00_03970	ENOG4105CY5	solute-binding protein
HZZ00_04005	ENOG4108M1A	Chitin-binding protein
HZZ00_04040	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HZZ00_04055	ENOG4105DEN	Luciferase family
HZZ00_04060	ENOG4105BZU	Histidine kinase
HZZ00_04110	ENOG4108ZM9	phosphoglycerate mutase
HZZ00_04125	ENOG4108JPV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HZZ00_04140	ENOG410804D	Sensor Signal Transduction Histidine Kinase
HZZ00_04145	ENOG4108NNZ	chitinase
HZZ00_04155	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_04170	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
HZZ00_04180	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_04190	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HZZ00_04195	ENOG4105ECQ	AraC Family Transcriptional Regulator
HZZ00_04210	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HZZ00_04225	ENOG4105E2D	ec 3.2.1.52
HZZ00_04230	ENOG4105DUU	IucA IucC family protein
HZZ00_04240	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
HZZ00_04250	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HZZ00_04290	ENOG4105C1G	acyl-Coa dehydrogenase
HZZ00_04295	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HZZ00_04305	ENOG4107QX3	carboxylase
HZZ00_04320	ENOG4105C29	acyl-CoA thioesterase
HZZ00_04330	ENOG4108XFF	
HZZ00_04340	ENOG4105CK7	Sodium proline symporter
HZZ00_04350	ENOG4105C7K	acetolactate synthase
HZZ00_04390	ENOG4105D17	glycoside hydrolase, family 3 domain protein
HZZ00_04405	ENOG4105HSS	phospholipase C
HZZ00_04410	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_04430	ENOG4105SUT	Transcriptional Regulator AraC Family
HZZ00_04460	ENOG4105CHP	RNA polymerase
HZZ00_04470	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
HZZ00_04475	ENOG4108RVA	ribokinase
HZZ00_04480	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HZZ00_04485	ENOG4105C2J	ABC transporter
HZZ00_04490	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_04500	ENOG4105C7H	Helicase, RecD TraA family
HZZ00_04535	ENOG4105EDK	PfkB domain protein
HZZ00_04545	ENOG4105DH8	myo-inositol catabolism
HZZ00_04550	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
HZZ00_04555	ENOG4105C26	Dehydrogenase
HZZ00_04565	ENOG4105CJ1	ABC, transporter
HZZ00_04595	ENOG4105S2J	secreted protein
HZZ00_04640	ENOG4108JQ1	Dehydrogenase
HZZ00_04645	ENOG4105D9P	serine threonine protein kinase
HZZ00_04670	ENOG4105KVH	Transcriptional regulator
HZZ00_04675	ENOG4107S5I	aldo keto reductase
HZZ00_04695	ENOG4105VHU	single-stranded DNA-binding protein
HZZ00_04735	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HZZ00_04755	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HZZ00_04785	ENOG4105CT1	(ABC) transporter
HZZ00_04805	ENOG4105F8D	glycoside hydrolase family 4
HZZ00_04810	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
HZZ00_04815	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
HZZ00_04825	ENOG4105E2R	ROK family
HZZ00_04835	ENOG4105D8X	mechanosensitive ion channel
HZZ00_04850	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HZZ00_04925	ENOG4108KQ5	Integrase catalytic subunit
HZZ00_04950	ENOG4105MC2	DSBA oxidoreductase
HZZ00_04960	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HZZ00_04965	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HZZ00_04970	ENOG4105C85	amino acid
HZZ00_04985	ENOG4105E2Y	ABC, transporter
HZZ00_04990	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HZZ00_05000	ENOG4105E2R	ROK family
HZZ00_05010	ENOG4105C85	amino acid
HZZ00_05040	ENOG4108TGC	Acyltransferase
HZZ00_05055	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
HZZ00_05105	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HZZ00_05110	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HZZ00_05115	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HZZ00_05120	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HZZ00_05130	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HZZ00_05135	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HZZ00_05145	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HZZ00_05150	ENOG4105DFF	Rod shape-determining protein mreb
HZZ00_05165	ENOG4105CJN	penicillin-binding protein
HZZ00_05170	ENOG4105CNI	cell division protein FtsW
HZZ00_05190	ENOG4105C03	ribonuclease
HZZ00_05195	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HZZ00_05200	ENOG4105K46	50S ribosomal protein l27
HZZ00_05205	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HZZ00_05230	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HZZ00_05240	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HZZ00_05255	ENOG4105D0M	Protease HtpX homolog
HZZ00_05270	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HZZ00_05280	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HZZ00_05285	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HZZ00_05305	ENOG4105C8T	Leucyl-tRNA synthetase
HZZ00_05315	ENOG4105EPR	degv family
HZZ00_05320	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
HZZ00_05335	ENOG4108YYC	ycei family
HZZ00_05350	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HZZ00_05355	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HZZ00_05360	ENOG4108IQE	Amp-dependent synthetase and ligase
HZZ00_05385	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
HZZ00_05390	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HZZ00_05395	ENOG4107QWG	2-Nitropropane dioxygenase
HZZ00_05415	ENOG4107RE3	peptidase, S41
HZZ00_05420	ENOG4107YU2	histidine triad (hIT) protein
HZZ00_05425	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HZZ00_05445	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HZZ00_05455	ENOG4105MSB	protein, conserved in bacteria
HZZ00_05460	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
HZZ00_05480	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HZZ00_05510	ENOG4105D4Y	metalloprotease
HZZ00_05515	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HZZ00_05530	ENOG41064MX	Tetr family transcriptional regulator
HZZ00_05535	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
HZZ00_05585	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
HZZ00_05590	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HZZ00_05600	ENOG4105FAV	ABC, transporter
HZZ00_05605	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HZZ00_05610	ENOG4105DSE	periplasmic solute binding protein
HZZ00_05615	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
HZZ00_05630	ENOG4108FN7	Aldo keto reductase
HZZ00_05635	ENOG4105MKU	Transcriptional regulator
HZZ00_05680	ENOG4105E2R	ROK family
HZZ00_05685	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HZZ00_05705	ENOG4105WEM	extracellular solute-binding protein
HZZ00_05715	ENOG4105DRS	transport system, permease
HZZ00_05750	ENOG4108IUW	ABC transporter
HZZ00_05780	ENOG4105I82	acetyl xylan esterase
HZZ00_05790	ENOG4108RPX	mosc domain containing protein
HZZ00_05800	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
HZZ00_05815	ENOG4108UB4	uncharacterized protein ygjQ
HZZ00_05820	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HZZ00_05830	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HZZ00_05835	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HZZ00_05900	ENOG4105DFF	Rod shape-determining protein mreb
HZZ00_05930	ENOG4105D8K	carboxyl transferase
HZZ00_05935	ENOG4105CEY	Amp-dependent synthetase and ligase
HZZ00_05975	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HZZ00_05980	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HZZ00_06005	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HZZ00_06015	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HZZ00_06070	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HZZ00_06075	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HZZ00_06085	ENOG4105EXN	Sulfate transport protein CysZ
HZZ00_06095	ENOG4105CHJ	isochorismatase hydrolase
HZZ00_06100	ENOG4105CHJ	isochorismatase hydrolase
HZZ00_06110	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HZZ00_06130	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HZZ00_06135	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HZZ00_06165	ENOG4105VUF	Transcriptional regulator
HZZ00_06170	ENOG4105CPC	Aldo Keto reductase
HZZ00_06195	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HZZ00_06240	ENOG4105DAX	Pfam:DUF2983
HZZ00_06255	ENOG4105BZ4	penicillin-binding protein
HZZ00_06300	ENOG4105EEM	helicase
HZZ00_06330	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
HZZ00_06385	ENOG4105CSH	Transporter
HZZ00_06395	ENOG4105XPP	Protein of unknown function (DUF1275)
HZZ00_06415	ENOG4105BZ1	(ABC) transporter
HZZ00_06470	ENOG4108SGK	Tetr family transcriptional regulator
HZZ00_06475	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HZZ00_06480	ENOG4107QVI	Methyltransferase, type 11
HZZ00_06500	ENOG4108RU2	n-acetylmuramoyl-l-alanine amidase
HZZ00_06520	ENOG4108S01	response regulator
HZZ00_06530	ENOG4105BZU	Histidine kinase
HZZ00_06540	ENOG4108M15	ABC transporter
HZZ00_06560	ENOG4105EGD	dinuclear metal center protein, YbgI family
HZZ00_06575	ENOG4108UHU	Aldolase
HZZ00_06580	ENOG4107XFJ	UPF0246 protein
HZZ00_06585	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HZZ00_06630	ENOG4108VGI	doxx family
HZZ00_06650	ENOG4105C2C	drug resistance transporter, Bcr CflA
HZZ00_06655	ENOG4107S1E	Beta-lactamase
HZZ00_06670	ENOG4106A0S	
HZZ00_06680	ENOG4105DBE	peroxidase
HZZ00_06730	ENOG4107XZ0	Peptidase M50
HZZ00_06755	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HZZ00_06760	ENOG4105C57	major facilitator superfamily
HZZ00_06775	ENOG4105F27	Major Facilitator
HZZ00_06845	ENOG41081JD	Transcriptional regulator
HZZ00_06850	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HZZ00_06855	ENOG4105C5F	glutamine synthetase
HZZ00_06860	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HZZ00_06895	ENOG4105FBN	Acid phosphatase
HZZ00_06910	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HZZ00_06920	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_06930	ENOG4105D56	permease protein
HZZ00_06935	ENOG4105EG2	ABC transporter, permease
HZZ00_06940	ENOG4105CG3	alpha amylase, catalytic region
HZZ00_06980	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_06995	ENOG4107NHD	transcriptional regulator
HZZ00_07000	ENOG4107R5B	glutamine synthetase
HZZ00_07010	ENOG4108222	arsenate reductase
HZZ00_07030	ENOG4105D0M	Protease HtpX homolog
HZZ00_07045	ENOG4105C5F	glutamine synthetase
HZZ00_07065	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HZZ00_07070	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HZZ00_07110	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HZZ00_07130	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HZZ00_07135	ENOG410813T	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
HZZ00_07150	ENOG4105CRK	lysyL-tRNA synthetase
HZZ00_07155	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
HZZ00_07165	ENOG4108YZT	Adenosylcobinamide kinase
HZZ00_07175	ENOG4105C0H	protease
HZZ00_07200	ENOG4105BZU	Histidine kinase
HZZ00_07205	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_07215	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HZZ00_07235	ENOG4107T4Z	adenosine kinase
HZZ00_07245	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
HZZ00_07250	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HZZ00_07255	ENOG4105MCD	Part of cytochrome c oxidase, its function is
HZZ00_07260	ENOG4107UBC	ErfK ybiS ycfS ynhG family protein
HZZ00_07270	ENOG4105CCU	oxidase (Subunit III)
HZZ00_07275	ENOG4107UDY	cytochrome C
HZZ00_07280	ENOG4107EUI	c reductase, iron-sulfur
HZZ00_07285	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HZZ00_07290	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HZZ00_07325	ENOG4105K4H	Nlp p60 protein
HZZ00_07340	ENOG4105UQX	Mate efflux family protein
HZZ00_07350	ENOG4105JNK	Glycosyl transferase (Group 1
HZZ00_07370	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
HZZ00_07380	ENOG4105DKQ	ROK family
HZZ00_07405	ENOG4105ENE	Histidine kinase
HZZ00_07415	ENOG4105CTQ	phosphohexokinase
HZZ00_07430	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
HZZ00_07440	ENOG4108UQY	Iron-storage protein
HZZ00_07450	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
HZZ00_07460	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HZZ00_07490	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HZZ00_07515	ENOG4107Z3H	Transcriptional regulator, TetR family
HZZ00_07555	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HZZ00_07565	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HZZ00_07575	ENOG4105CJN	penicillin-binding protein
HZZ00_07580	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HZZ00_07590	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HZZ00_07595	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HZZ00_07605	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HZZ00_07615	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HZZ00_07620	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HZZ00_07625	ENOG4105DFA	alanine racemase domain protein
HZZ00_07630	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
HZZ00_07640	ENOG4107VQS	DivIVA family
HZZ00_07645	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HZZ00_07655	ENOG4107ZIW	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HZZ00_07665	ENOG41082BV	acetyltransferase
HZZ00_07710	ENOG4105C0B	DNA polymerase III (alpha subunit)
HZZ00_07740	ENOG4108Z66	YbaK ebsC protein
HZZ00_07745	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HZZ00_07760	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HZZ00_07765	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HZZ00_07770	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HZZ00_07780	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HZZ00_07785	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HZZ00_07790	ENOG4108176	endoribonuclease L-psp
HZZ00_07795	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HZZ00_07810	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
HZZ00_07820	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HZZ00_07850	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HZZ00_07855	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HZZ00_07860	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HZZ00_07870	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HZZ00_07875	ENOG4105CI0	Citrate lyase
HZZ00_07880	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HZZ00_07885	ENOG4108RVA	ribokinase
HZZ00_07905	ENOG41065RQ	ADP-ribosylation crystallin J1
HZZ00_07915	ENOG4105CBC	glutamate synthase
HZZ00_07940	ENOG41063TF	transcriptional regulator (AraC
HZZ00_07945	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
HZZ00_07990	ENOG4108IV0	ABC, transporter
HZZ00_07995	ENOG4105C0Z	ABC transporter
HZZ00_08000	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HZZ00_08005	ENOG4105C32	Amino acid ABC transporter (Permease)
HZZ00_08010	ENOG4105CP9	extracellular ligand-binding receptor
HZZ00_08015	ENOG4108TZA	Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity)
HZZ00_08040	ENOG4105CQ7	ATP-dependent helicase
HZZ00_08050	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HZZ00_08065	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HZZ00_08080	ENOG4108D32	Methyltransferase
HZZ00_08095	ENOG4105K5X	acetyltransferase
HZZ00_08160	ENOG4105D7N	magnesium and cobalt transport protein CorA
HZZ00_08165	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HZZ00_08170	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HZZ00_08175	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
HZZ00_08180	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HZZ00_08185	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HZZ00_08190	ENOG4105BZU	Histidine kinase
HZZ00_08195	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HZZ00_08220	ENOG4105CSH	Transporter
HZZ00_08225	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HZZ00_08230	ENOG4105CDA	abc transporter atp-binding protein
HZZ00_08235	ENOG4105E5Q	amino acid AbC transporter
HZZ00_08240	ENOG4107R0W	ABC transporter
HZZ00_08245	ENOG4105KVH	Transcriptional regulator
HZZ00_08260	ENOG4105DND	Transcriptional regulator
HZZ00_08275	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HZZ00_08285	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_08300	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HZZ00_08305	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HZZ00_08310	ENOG4105CHW	UPF0052 protein
HZZ00_08315	ENOG4105CIE	May be required for sporulation (By similarity)
HZZ00_08320	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HZZ00_08325	ENOG4105BZA	Phosphoglycerate kinase
HZZ00_08330	ENOG4105CP7	Triose-phosphate isomerase
HZZ00_08345	ENOG4107QP8	phosphohexose isomerase
HZZ00_08355	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
HZZ00_08370	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HZZ00_08380	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HZZ00_08395	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
HZZ00_08405	ENOG4105CJ1	ABC, transporter
HZZ00_08410	ENOG4108AQF	aminoglycoside N(3)-acetyltransferase
HZZ00_08425	ENOG4105JRK	feS assembly protein SufD
HZZ00_08435	ENOG4105C3K	feS assembly ATPase SufC
HZZ00_08440	ENOG4105C9B	Cysteine desulfurase
HZZ00_08445	ENOG4108UNV	SUF system FeS assembly protein, NifU family
HZZ00_08455	ENOG410814C	multidrug resistance protein
HZZ00_08460	ENOG4108RFG	Tetr family transcriptional regulator
HZZ00_08465	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
HZZ00_08475	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HZZ00_08555	ENOG4105E9Z	Nad-dependent epimerase dehydratase
HZZ00_08585	ENOG41069M3	Transcriptional regulator
HZZ00_08605	ENOG4105C9B	Cysteine desulfurase
HZZ00_08610	ENOG4105EV8	ectoine hydroxylase
HZZ00_08615	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
HZZ00_08620	ENOG4108JPW	Aminotransferase
HZZ00_08625	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
HZZ00_08630	ENOG4105C5R	Aminotransferase
HZZ00_08635	ENOG4106PMH	Extracellular solute-binding protein family 3
HZZ00_08640	ENOG4105E5Q	amino acid AbC transporter
HZZ00_08665	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
HZZ00_08670	ENOG41081F0	Precorrin-8x methylmutase
HZZ00_08675	ENOG4105E4R	Precorrin-3B C17-methyltransferase
HZZ00_08685	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
HZZ00_08700	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HZZ00_08705	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HZZ00_08715	ENOG4105CTK	cobaltochelatase, cobn subunit
HZZ00_08720	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HZZ00_08725	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
HZZ00_08745	ENOG4107W7X	Aldolase
HZZ00_08765	ENOG4105C5H	ABC transporter
HZZ00_08775	ENOG41060WC	Enoyl-CoA hydratase
HZZ00_08785	ENOG4105VBF	alkaline shock protein
HZZ00_08815	ENOG4105BZP	glycoside hydrolase 15-related
HZZ00_08830	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HZZ00_08840	ENOG4108MXC	l-carnitine dehydratase bile acid-inducible protein F
HZZ00_08855	ENOG4107QN1	sodium solute
HZZ00_08860	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HZZ00_08875	ENOG4105Y3U	Transglycosylase-associated protein
HZZ00_08880	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HZZ00_08910	ENOG4107YCY	Transcriptional regulator
HZZ00_08930	ENOG4105EAC	phosphoserine phosphatase
HZZ00_08935	ENOG4105IDI	abc transporter atp-binding protein
HZZ00_08945	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HZZ00_08960	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_08975	ENOG4105DKW	ABC transporter
HZZ00_08995	ENOG4108V1U	phospholipid-binding protein
HZZ00_09005	ENOG4108VX5	3-methyladenine DNA glycosylase
HZZ00_09035	ENOG4105DSU	hydrolase
HZZ00_09040	ENOG4105DQ5	transport system permease protein
HZZ00_09045	ENOG4105TVJ	transport system, permease
HZZ00_09050	ENOG4105E0A	ABC, transporter
HZZ00_09070	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HZZ00_09075	ENOG4108KQ5	Integrase catalytic subunit
HZZ00_09080	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HZZ00_09090	ENOG4107QPH	glycogen) synthase
HZZ00_09105	ENOG4105BZP	glycoside hydrolase 15-related
HZZ00_09110	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HZZ00_09115	ENOG4108YZ4	nudix hydrolase
HZZ00_09125	ENOG4105DCF	alanine dehydrogenase
HZZ00_09140	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HZZ00_09145	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HZZ00_09150	ENOG4105FE9	pseudouridine synthase
HZZ00_09155	ENOG41065RQ	ADP-ribosylation crystallin J1
HZZ00_09160	ENOG410756H	nucleotidyltransferase
HZZ00_09185	ENOG4105CAT	Cytidine monophosphate kinase
HZZ00_09195	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HZZ00_09210	ENOG4105MS9	Resuscitation-promoting factor
HZZ00_09220	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HZZ00_09230	ENOG4105C57	major facilitator superfamily
HZZ00_09235	ENOG4105C1G	acyl-Coa dehydrogenase
HZZ00_09240	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
HZZ00_09250	ENOG4107UBR	Extracellular solute-binding protein family 3
HZZ00_09255	ENOG4105EAD	ABC transporter
HZZ00_09265	ENOG4105CDA	abc transporter atp-binding protein
HZZ00_09275	ENOG4106NMR	serine protease
HZZ00_09285	ENOG4105C0B	DNA polymerase III (alpha subunit)
HZZ00_09310	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HZZ00_09325	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
HZZ00_09345	ENOG4108TCJ	secreted hydrolase
HZZ00_09355	ENOG4105IYB	L-carnitine dehydratase bile acid-inducible protein F
HZZ00_09385	ENOG4105F1J	Homogentisate 1,2-dioxygenase
HZZ00_09395	ENOG4108SGK	Tetr family transcriptional regulator
HZZ00_09420	ENOG4108ZHR	arsR family transcriptional regulator
HZZ00_09430	ENOG4105C1G	acyl-Coa dehydrogenase
HZZ00_09450	ENOG4108Z4X	TRANSCRIPTIONal
HZZ00_09480	ENOG4105EHZ	conserved protein UCP016719
HZZ00_09490	ENOG4105CEY	Amp-dependent synthetase and ligase
HZZ00_09495	ENOG4108IG5	Transcriptional regulator
HZZ00_09500	ENOG4105DND	Transcriptional regulator
HZZ00_09515	ENOG4105PTV	Nudix Hydrolase
HZZ00_09540	ENOG4105C6Z	Gluconate
HZZ00_09545	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HZZ00_09550	ENOG4105C6F	GntR Family Transcriptional Regulator
HZZ00_09555	ENOG4105K5B	UPF0225 protein
HZZ00_09580	ENOG4105DCG	PHP domain protein
HZZ00_09600	ENOG4105S2J	secreted protein
HZZ00_09620	ENOG4105CPC	Aldo Keto reductase
HZZ00_09625	ENOG4105DYW	oxidoreductase
HZZ00_09635	ENOG4105D7N	magnesium and cobalt transport protein CorA
HZZ00_09640	ENOG4108RH7	phosphoglycerate mutase
HZZ00_09655	ENOG4105C8N	cysteinyl-tRNA synthetase
HZZ00_09665	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HZZ00_09670	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HZZ00_09675	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HZZ00_09680	ENOG4108K8U	Glycerol operon regulatory protein
HZZ00_09685	ENOG4105C3R	Methionine synthase
HZZ00_09690	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HZZ00_09695	ENOG4105DEF	Extracellular solute-binding protein, family 5
HZZ00_09700	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_09730	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
HZZ00_09735	ENOG4105E5F	proteasome
HZZ00_09740	ENOG4105WFD	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity)
HZZ00_09750	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
HZZ00_09755	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
HZZ00_09760	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_09770	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
HZZ00_09805	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HZZ00_09810	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HZZ00_09845	ENOG4105D3G	Pseudouridine synthase
HZZ00_09865	ENOG4105HFS	5'-3' exonuclease
HZZ00_09870	ENOG4108IJ7	Glycine betaine
HZZ00_09875	ENOG4108HQS	Glycine betaine
HZZ00_09885	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HZZ00_09900	ENOG4108Z86	Glutamine amidotransferase
HZZ00_09905	ENOG41073TP	transcriptional regulator
HZZ00_09910	ENOG4105C5F	glutamine synthetase
HZZ00_09915	ENOG4105C26	Dehydrogenase
HZZ00_09950	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HZZ00_09955	ENOG41084BS	50S ribosomal protein L35
HZZ00_09960	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HZZ00_09965	ENOG4108RWN	rrna methyltransferase
HZZ00_09970	ENOG4105BZU	Histidine kinase
HZZ00_09975	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HZZ00_09980	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HZZ00_09995	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HZZ00_10015	ENOG4105CIS	alcohol dehydrogenase
HZZ00_10025	ENOG4105F32	YngK protein
HZZ00_10055	ENOG4105CKK	Glycosyl transferase, family 2
HZZ00_10065	ENOG4105CQF	Transcriptional regulator
HZZ00_10070	ENOG4105EFZ	amidohydrolase
HZZ00_10085	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HZZ00_10090	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HZZ00_10095	ENOG4105CAS	nag kinase
HZZ00_10100	ENOG4105C8Y	Acetylornithine aminotransferase
HZZ00_10105	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
HZZ00_10120	ENOG4105BZ1	(ABC) transporter
HZZ00_10130	ENOG4105CJ2	(LipO)protein
HZZ00_10140	ENOG4108DEF	Globin
HZZ00_10145	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HZZ00_10150	ENOG4105BZU	Histidine kinase
HZZ00_10165	ENOG4105CDH	Citrulline--aspartate ligase
HZZ00_10170	ENOG4105CH7	arginosuccinase
HZZ00_10180	ENOG4105ECQ	AraC Family Transcriptional Regulator
HZZ00_10190	ENOG4105RJZ	Transcriptional regulator
HZZ00_10195	ENOG4105C57	major facilitator superfamily
HZZ00_10200	ENOG4107R16	Multicopper oxidase
HZZ00_10205	ENOG4105CEY	Amp-dependent synthetase and ligase
HZZ00_10235	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HZZ00_10240	ENOG4108UMI	ABC transporter, permease
HZZ00_10245	ENOG4105D01	(LipO)protein
HZZ00_10260	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
HZZ00_10265	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HZZ00_10320	ENOG4105CRQ	synthase (Component I)
HZZ00_10355	ENOG4105KF0	sporulation and cell division protein, SsgA
HZZ00_10380	ENOG4108IRC	dna polymerase iii
HZZ00_10395	ENOG4105C22	threonyL-tRNA synthetase
HZZ00_10420	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
HZZ00_10425	ENOG4105E2K	Glycosyl transferase (Group 1
HZZ00_10435	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
HZZ00_10440	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
HZZ00_10445	ENOG4105CDY	transcriptional regulatory protein
HZZ00_10450	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HZZ00_10455	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HZZ00_10460	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HZZ00_10470	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HZZ00_10475	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HZZ00_10480	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HZZ00_10485	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HZZ00_10490	ENOG4105C99	atpase involved in dna repair
HZZ00_10495	ENOG4108ZR3	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)
HZZ00_10505	ENOG4105CUT	histidyl-tRNA synthetase
HZZ00_10520	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HZZ00_10540	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HZZ00_10545	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HZZ00_10555	ENOG4105E2X	shikimate dehydrogenase
HZZ00_10560	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HZZ00_10565	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HZZ00_10570	ENOG4105D49	3-dehydroquinate synthase
HZZ00_10580	ENOG4105DC7	peptidase M24
HZZ00_10585	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HZZ00_10590	ENOG410803B	Involved in the transcription termination process (By similarity)
HZZ00_10600	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HZZ00_10605	ENOG4105CXT	aspartate transcarbamylase
HZZ00_10610	ENOG4105CD3	dihydroorotase
HZZ00_10620	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HZZ00_10625	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HZZ00_10630	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HZZ00_10635	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
HZZ00_10645	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HZZ00_10660	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HZZ00_10680	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HZZ00_10690	ENOG4105DJV	ribulose-phosphate 3-epimerase
HZZ00_10695	ENOG4105DKT	Transcriptional regulator
HZZ00_10720	ENOG4105CUB	amino acid
HZZ00_10730	ENOG4108TZY	GntR Family Transcriptional Regulator
HZZ00_10775	ENOG4105C2W	permease
HZZ00_10790	ENOG4105E2R	ROK family
HZZ00_10805	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HZZ00_10810	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HZZ00_10815	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
HZZ00_10820	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HZZ00_11090	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HZZ00_11275	ENOG4105EW9	transcriptional regulator AsnC family
HZZ00_11285	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
HZZ00_11290	ENOG4105FS0	cytoplasmic membrane protein
HZZ00_11300	ENOG4105Q70	
HZZ00_11305	ENOG4105DEU	major facilitator superfamily
HZZ00_11315	ENOG4108VW9	Membrane
HZZ00_11335	ENOG4105JXB	ankyrin repeat-containing protein
HZZ00_11350	ENOG4108MJN	Glycosyl Transferase
HZZ00_11365	ENOG4105P4J	Allophanate hydrolase, subunit 1
HZZ00_11370	ENOG4105E7W	lamb ycsf family protein
HZZ00_11375	ENOG4105CFM	UPF0317 protein
HZZ00_11405	ENOG41069M3	Transcriptional regulator
HZZ00_11420	ENOG4105GWZ	Roadblock lc7 family protein
HZZ00_11440	ENOG4105BZU	Histidine kinase
HZZ00_11455	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HZZ00_11465	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HZZ00_11470	ENOG4105C5Y	PTS System
HZZ00_11515	ENOG4108UW8	fha domain-containing protein
HZZ00_11535	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HZZ00_11545	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HZZ00_11550	ENOG4105F4R	Transcriptional regulator mode
HZZ00_11610	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HZZ00_11645	ENOG4105CSW	GntR family transcriptional regulator
HZZ00_11650	ENOG4108Q5Y	Membrane
HZZ00_11685	ENOG4105CHR	reductase
HZZ00_11690	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
HZZ00_11695	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HZZ00_11715	ENOG4105EP9	oxidoreductase
HZZ00_11720	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HZZ00_11745	ENOG4105CHU	acetyl-coa acetyltransferase
HZZ00_11760	ENOG4108ARV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HZZ00_11800	ENOG4108Z0R	Transferase
HZZ00_11805	ENOG4108UW5	maltose o-acetyltransferase
HZZ00_11815	ENOG4107VRI	Transcriptional regulator
HZZ00_11830	ENOG41082SX	arsR family transcriptional regulator
HZZ00_11835	ENOG4107QTZ	amino acid
HZZ00_11840	ENOG4105K4P	CoA-binding domain protein
HZZ00_11855	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HZZ00_11865	ENOG4105EYH	Exonuclease
HZZ00_11875	ENOG4106A3M	Cytochrome p-450
HZZ00_11915	ENOG4106HB6	Alpha beta hydrolase
HZZ00_11925	ENOG4108KPJ	rna polymerase sigma factor
HZZ00_11930	ENOG4105FDP	GntR family transcriptional regulator
HZZ00_11935	ENOG4105DKQ	ROK family
HZZ00_11945	ENOG4108VCA	G U mismatch-specific DNA glycosylase
HZZ00_11950	ENOG4105C83	adenylosuccinate lyase
HZZ00_11955	ENOG4105ENX	hydrolase
HZZ00_11990	ENOG4108R6G	acetyltransferase
HZZ00_11995	ENOG4105FBW	Monooxygenase
HZZ00_12005	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HZZ00_12020	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HZZ00_12025	ENOG4107WHG	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HZZ00_12030	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HZZ00_12035	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HZZ00_12090	ENOG4105C8Y	Acetylornithine aminotransferase
HZZ00_12095	ENOG4105CIK	Amidinotransferase
HZZ00_12115	ENOG4105CTQ	phosphohexokinase
HZZ00_12120	ENOG4105F1K	Glutamine amidotransferase
HZZ00_12130	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HZZ00_12140	ENOG4105C1G	acyl-Coa dehydrogenase
HZZ00_12150	ENOG4106A3M	Cytochrome p-450
HZZ00_12155	ENOG41065KQ	synthase
HZZ00_12165	ENOG4105C26	Dehydrogenase
HZZ00_12175	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
HZZ00_12180	ENOG4105C3M	thioredoxin reductase
HZZ00_12190	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HZZ00_12195	ENOG4105D2B	acyl-CoA dehydrogenase
HZZ00_12200	ENOG4105D2B	acyl-CoA dehydrogenase
HZZ00_12230	ENOG4105CPQ	Dehydrogenase
HZZ00_12255	ENOG4106W5V	Membrane
HZZ00_12345	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HZZ00_12420	ENOG4105CFG	Acts as a chaperone (By similarity)
HZZ00_12425	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HZZ00_12460	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HZZ00_12465	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HZZ00_12475	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HZZ00_12480	ENOG4105CTU	Proline racemase
HZZ00_12505	ENOG4105C1J	atp-dependent rna helicase
HZZ00_12510	ENOG4107RN3	metallophosphoesterase
HZZ00_12520	ENOG4105CEY	Amp-dependent synthetase and ligase
HZZ00_12565	ENOG4105C26	Dehydrogenase
HZZ00_12570	ENOG4107RR1	TRANSCRIPTIONal
HZZ00_12580	ENOG4107SCA	Formamidase (EC 3.5.1.49)
HZZ00_12590	ENOG4105E2R	ROK family
HZZ00_12640	ENOG4105GWZ	Roadblock lc7 family protein
HZZ00_12650	ENOG4105C29	acyl-CoA thioesterase
HZZ00_12675	ENOG4105BZ1	(ABC) transporter
HZZ00_12705	ENOG4105BZ1	(ABC) transporter
HZZ00_12715	ENOG4105F95	Monooxygenase
HZZ00_12720	ENOG4107ZED	Uncharacterised protein family UPF0047
HZZ00_12725	ENOG4105DKW	ABC transporter
HZZ00_12760	ENOG4108M24	von Willebrand factor, type A
HZZ00_12785	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HZZ00_12795	ENOG4105GSW	
HZZ00_12820	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
HZZ00_12865	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HZZ00_12880	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HZZ00_12895	ENOG4105CSU	acyl-Coa dehydrogenase
HZZ00_12910	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HZZ00_12965	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HZZ00_13015	ENOG4105C10	Electron transfer flavoprotein
HZZ00_13030	ENOG41060NJ	transcriptional regulator
HZZ00_13050	ENOG4105I1F	Resistance protein
HZZ00_13060	ENOG4107PP3	Acetylornithine deacetylase
HZZ00_13065	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HZZ00_13090	ENOG41062KD	Inherit from COG: ketosteroid isomerase-like protein
HZZ00_13095	ENOG4107S9F	NmrA family
HZZ00_13110	ENOG4105C31	Tryptophanyl-tRNA synthetase
HZZ00_13130	ENOG4105E98	transcriptional regulator DeoR family
HZZ00_13135	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HZZ00_13140	ENOG4105D2N	Aldolase
HZZ00_13150	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
HZZ00_13155	ENOG4107RNR	Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA (By similarity)
HZZ00_13165	ENOG4105DKQ	ROK family
HZZ00_13200	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HZZ00_13225	ENOG4105CAY	ferredoxin--nadp reductase
HZZ00_13230	ENOG4105E8G	Major facilitator Superfamily
HZZ00_13260	ENOG4105MVE	transcriptional regulator
HZZ00_13270	ENOG4106F1P	AAA ATPase, central domain protein
HZZ00_13295	ENOG4107R8N	Glycosyl transferase, family 2
HZZ00_13300	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HZZ00_13330	ENOG4105BZU	Histidine kinase
HZZ00_13345	ENOG4108KQ5	Integrase catalytic subunit
HZZ00_13360	ENOG4106UDK	Cellulose-binding, family II
HZZ00_13365	ENOG4105K4I	Scp-like extracellular
HZZ00_13370	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HZZ00_13375	ENOG41086KC	Transcriptional regulator
HZZ00_13410	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HZZ00_13460	ENOG4105KJJ	Uncharacterized ACR, COG1993
HZZ00_13470	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HZZ00_13485	ENOG4108IJ0	Aspartate ammonia-lyase
HZZ00_13495	ENOG4107JC6	Membrane
HZZ00_13510	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HZZ00_13520	ENOG4105I82	acetyl xylan esterase
HZZ00_13550	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HZZ00_13570	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HZZ00_13600	ENOG4108UTZ	Dihydroxyacetone kinase
HZZ00_13605	ENOG4105CMT	Dihydroxyacetone kinase
HZZ00_13645	ENOG4106F1P	AAA ATPase, central domain protein
HZZ00_13665	ENOG4105EC2	ftsk spoIIIe
HZZ00_13680	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HZZ00_13695	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HZZ00_13705	ENOG4105CPK	Glycosyl transferase (Group 1
HZZ00_13710	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HZZ00_13715	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HZZ00_13720	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HZZ00_13750	ENOG4108YZG	isomerase
HZZ00_13775	ENOG4108U3T	pfkb domain protein
HZZ00_13785	ENOG4105CEY	Amp-dependent synthetase and ligase
HZZ00_13835	ENOG4105KF0	sporulation and cell division protein, SsgA
HZZ00_13845	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HZZ00_13855	ENOG4105CAQ	asparagine synthetase
HZZ00_13905	ENOG4107QTZ	amino acid
HZZ00_13920	ENOG4107S5I	aldo keto reductase
HZZ00_13935	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HZZ00_13945	ENOG4108M0I	Transcriptional regulator
HZZ00_13950	ENOG4105CPC	Aldo Keto reductase
HZZ00_13975	ENOG4108N6D	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HZZ00_14000	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HZZ00_14005	ENOG4107SET	aldo keto reductase
HZZ00_14020	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
HZZ00_14025	ENOG4105C7B	Threonine dehydratase
HZZ00_14060	ENOG4105C5X	domain protein
HZZ00_14160	ENOG4105CEP	NADH dehydrogenase
HZZ00_14175	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
HZZ00_14180	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HZZ00_14185	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
HZZ00_14195	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
HZZ00_14245	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HZZ00_14265	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
HZZ00_14275	ENOG4105EMU	Dehydrogenase
HZZ00_14290	ENOG4105DQE	DNA ligase
HZZ00_14295	ENOG4105CV8	reductase
HZZ00_14300	ENOG4107UNS	conserved inner membrane protein
HZZ00_14310	ENOG4105BZU	Histidine kinase
HZZ00_14370	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HZZ00_14405	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HZZ00_14415	ENOG4108SV8	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity)
HZZ00_14500	ENOG4105EM7	Selenocysteine-specific translation elongation factor
HZZ00_14510	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
HZZ00_14525	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HZZ00_14545	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HZZ00_14560	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HZZ00_14565	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HZZ00_14600	ENOG4105DQR	SNARE associated Golgi
HZZ00_14610	ENOG4105CPC	Aldo Keto reductase
HZZ00_14615	ENOG4105CSH	Transporter
HZZ00_14655	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HZZ00_14665	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HZZ00_14675	ENOG4105CMR	udp-glucose 4-epimerase
HZZ00_14730	ENOG4105KA0	thioesterase Superfamily protein
HZZ00_14740	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HZZ00_14745	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HZZ00_14750	ENOG4107RCI	amp-dependent synthetase and ligase
HZZ00_14755	ENOG4107G43	radical SAM domain protein
HZZ00_14800	ENOG4105KT7	mgtC SapB transporter
HZZ00_14810	ENOG4105F71	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HZZ00_14815	ENOG4108USZ	hydrogenase
HZZ00_14835	ENOG4105CQS	hydrogenase expression formation protein HypD
HZZ00_14840	ENOG4105C45	hydrogenase expression formation protein (HypE)
HZZ00_14870	ENOG4105DPX	Hydrogenase, large subunit
HZZ00_14905	ENOG4108PJD	permease
HZZ00_14930	ENOG41080XP	Cbs domain
HZZ00_14945	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HZZ00_14960	ENOG4107QRI	Phosphoketolase
HZZ00_14970	ENOG4105CJW	magnesium transporter
HZZ00_14980	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HZZ00_15030	ENOG41082SX	arsR family transcriptional regulator
HZZ00_15035	ENOG4107TB5	TRANSCRIPTIONal
HZZ00_15050	ENOG4105ECP	epimerase
HZZ00_15055	ENOG41064MX	Tetr family transcriptional regulator
HZZ00_15060	ENOG4105EYF	MMPL domain protein
HZZ00_15075	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HZZ00_15125	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HZZ00_15130	ENOG4105BZU	Histidine kinase
HZZ00_15145	ENOG4108Q50	Histidine kinase
HZZ00_15165	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
HZZ00_15170	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
HZZ00_15175	ENOG4105C7W	Xanthine dehydrogenase
HZZ00_15210	ENOG4108TCJ	secreted hydrolase
HZZ00_15225	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
HZZ00_15245	ENOG4106HK8	GPR1 FUN34 yaaH family protein
HZZ00_15270	ENOG4105ENE	Histidine kinase
HZZ00_15275	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_15285	ENOG4108KB2	LysR family Transcriptional regulator
HZZ00_15345	ENOG4105CUB	amino acid
HZZ00_15400	ENOG4105EGE	secreted protein
HZZ00_15430	ENOG4108VQR	secreted hydrolase
HZZ00_15470	ENOG4108NNZ	chitinase
HZZ00_15480	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
HZZ00_15485	ENOG4105D81	ABC transporter, permease
HZZ00_15490	ENOG4107TYH	extracellular solute-binding protein family 1
HZZ00_15495	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HZZ00_15515	ENOG4105EMU	Dehydrogenase
HZZ00_15520	ENOG4105CHR	reductase
HZZ00_15525	ENOG4105BZ1	(ABC) transporter
HZZ00_15555	ENOG4107R3A	FAD linked oxidase domain protein
HZZ00_15560	ENOG4107TE5	Lipid kinase
HZZ00_15575	ENOG4105EZR	dyp-type peroxidase family protein
HZZ00_15580	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HZZ00_15585	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HZZ00_15620	ENOG4108JCI	Transcriptional regulator
HZZ00_15635	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
HZZ00_15645	ENOG4105C71	hydrolase family 65, central catalytic
HZZ00_15670	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
HZZ00_15685	ENOG4105CIG	ABC transporter
HZZ00_15705	ENOG4108Z6Z	Transcriptional regulator
HZZ00_15795	ENOG4105VPX	protein, conserved in bacteria
HZZ00_15840	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HZZ00_15885	ENOG4105C3R	Methionine synthase
HZZ00_15890	ENOG4107T4Z	adenosine kinase
HZZ00_15905	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HZZ00_15920	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HZZ00_15925	ENOG4106N8J	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity)
HZZ00_15935	ENOG4105C28	cystathionine
HZZ00_15955	ENOG4107R16	Multicopper oxidase
HZZ00_15960	ENOG4105D5P	Methylmalonyl-coA mutase
HZZ00_15980	ENOG4105C5F	glutamine synthetase
HZZ00_15995	ENOG4107GD3	Catalyzes the conversion of acetoacetate to acetone and carbon dioxide (By similarity)
HZZ00_16000	ENOG4105C26	Dehydrogenase
HZZ00_16010	ENOG4105ERH	Fumarylacetoacetate hydrolase
HZZ00_16015	ENOG4108X07	Tetr family transcriptional regulator
HZZ00_16025	ENOG4105C26	Dehydrogenase
HZZ00_16030	ENOG4108Z86	Glutamine amidotransferase
HZZ00_16035	ENOG4105GVJ	transcriptional regulator
HZZ00_16050	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
HZZ00_16165	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HZZ00_16170	ENOG4105KI2	Urea amidohydrolase subunit beta
HZZ00_16175	ENOG4105CQM	Urea amidohydrolase subunit alpha
HZZ00_16185	ENOG4107S16	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
HZZ00_16190	ENOG4105ICD	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HZZ00_16205	ENOG4105CAY	ferredoxin--nadp reductase
HZZ00_16225	ENOG4105CSA	Coproporphyrinogen iii oxidase
HZZ00_16275	ENOG41080V3	Major Facilitator superfamily
HZZ00_16280	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
HZZ00_16305	ENOG4105C2X	Arabinose 5-phosphate isomerase
HZZ00_16355	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
HZZ00_16370	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
HZZ00_16390	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
HZZ00_16395	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
HZZ00_16440	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HZZ00_16445	ENOG4108Z40	Transcriptional regulator
HZZ00_16450	ENOG41068WN	
HZZ00_16480	ENOG4105F0K	SARP family transcriptional regulator
HZZ00_16510	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HZZ00_16520	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HZZ00_16540	ENOG4105CPC	Aldo Keto reductase
HZZ00_16555	ENOG4107QQG	Dehydrogenase
HZZ00_16560	ENOG4107EG8	signal transduction protein with EFhand domain
HZZ00_16570	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HZZ00_16580	ENOG4108KB0	deacetylase
HZZ00_16600	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HZZ00_16610	ENOG4108QDE	fad dependent oxidoreductase
HZZ00_16615	ENOG4105CEY	Amp-dependent synthetase and ligase
HZZ00_16625	ENOG410846T	CoA-transferase family III
HZZ00_16630	ENOG4105CEY	Amp-dependent synthetase and ligase
HZZ00_16640	ENOG4105VUF	Transcriptional regulator
HZZ00_16645	ENOG4105D9U	N-acetyltransferase
HZZ00_16650	ENOG4105JZI	cytochrome P450
HZZ00_16670	ENOG4105CAY	ferredoxin--nadp reductase
HZZ00_16675	ENOG4105CEY	Amp-dependent synthetase and ligase
HZZ00_16680	ENOG4106NZI	LysR family Transcriptional regulator
HZZ00_16690	ENOG4108KEZ	Dehydrogenase
HZZ00_16740	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HZZ00_16780	ENOG4105S7M	extracellular small neutral protease
HZZ00_16785	ENOG4108KXM	LysR family Transcriptional regulator
HZZ00_16795	ENOG4105C0I	Conserved Protein
HZZ00_16820	ENOG4106T9R	serine protease
HZZ00_16835	ENOG4106T9R	serine protease
HZZ00_16950	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HZZ00_16980	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_16985	ENOG4105EF1	ribulokinase
HZZ00_16995	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
HZZ00_17005	ENOG4105C2J	ABC transporter
HZZ00_17010	ENOG4105CNN	ABC, transporter
HZZ00_17035	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
HZZ00_17055	ENOG4105ECY	inositol monophosphatase
HZZ00_17075	ENOG4105ETX	regulatoR
HZZ00_17145	ENOG4108YYC	ycei family
HZZ00_17150	ENOG4108YYC	ycei family
HZZ00_17155	ENOG4107QM2	Aldo Keto reductase
HZZ00_17175	ENOG4105W06	Cupin 2, conserved barrel domain protein
HZZ00_17195	ENOG4108U3T	pfkb domain protein
HZZ00_17200	ENOG4108PVU	Nucleotidyl transferase
HZZ00_17225	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HZZ00_17230	ENOG4108JPW	Aminotransferase
HZZ00_17235	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
HZZ00_17265	ENOG4105D56	permease protein
HZZ00_17270	ENOG4105EG2	ABC transporter, permease
HZZ00_17275	ENOG4105CG3	alpha amylase, catalytic region
HZZ00_17280	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_17305	ENOG4105CJQ	hydrolase, family 31
HZZ00_17325	ENOG4105E8R	UPF0173 metal-dependent hydrolase
HZZ00_17330	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
HZZ00_17415	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HZZ00_17425	ENOG4108IXY	short-chain dehydrogenase reductase
HZZ00_17470	ENOG4107U9T	Pfam:Ribonuclease_BN
HZZ00_17490	ENOG41079KZ	Major Facilitator Superfamily
HZZ00_17495	ENOG4105C26	Dehydrogenase
HZZ00_17520	ENOG4105CHR	reductase
HZZ00_17530	ENOG4105C7K	acetolactate synthase
HZZ00_17555	ENOG4105VUF	Transcriptional regulator
HZZ00_17560	ENOG4105DJ2	Major Facilitator Superfamily
HZZ00_17595	ENOG4105F0K	SARP family transcriptional regulator
HZZ00_17600	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HZZ00_17630	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_17640	ENOG4108HMN	Caspase domain
HZZ00_17690	ENOG4105C3U	ABC transporter
HZZ00_17700	ENOG4105DEF	Extracellular solute-binding protein, family 5
HZZ00_17710	ENOG4105I82	acetyl xylan esterase
HZZ00_17720	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HZZ00_17730	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
HZZ00_17745	ENOG4105CWX	Alpha-1,2-mannosidase
HZZ00_17750	ENOG4105GTG	Isochorismatase
HZZ00_17810	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_17815	ENOG4105PY6	Phenolic acid decarboxylase
HZZ00_17825	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
HZZ00_17830	ENOG4105DA5	(ABC) transporter
HZZ00_17845	ENOG4105ENX	hydrolase
HZZ00_17860	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
HZZ00_17875	ENOG4105E98	transcriptional regulator DeoR family
HZZ00_17880	ENOG4106UW1	Major Facilitator superfamily
HZZ00_17895	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HZZ00_17900	ENOG4107RJ1	sodium solute
HZZ00_17910	ENOG4106KNT	transcriptional regulator
HZZ00_17915	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HZZ00_17930	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
HZZ00_17945	ENOG4105EQK	-acetyltransferase
HZZ00_17975	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_17980	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HZZ00_17990	ENOG4105F38	ABC transporter, permease
HZZ00_17995	ENOG4105D38	putrescine abc transporter
HZZ00_18005	ENOG4108KPW	sugar kinase
HZZ00_18090	ENOG410804X	Transcriptional regulator
HZZ00_18100	ENOG4105DM4	PTS System
HZZ00_18170	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HZZ00_18180	ENOG4108HMN	Caspase domain
HZZ00_18215	ENOG4106A3M	Cytochrome p-450
HZZ00_18240	ENOG4108RWI	nicotinamidase
HZZ00_18360	ENOG4105CEY	Amp-dependent synthetase and ligase
HZZ00_18375	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HZZ00_18400	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HZZ00_18435	ENOG4105BZ1	(ABC) transporter
HZZ00_18440	ENOG4105BZ1	(ABC) transporter
HZZ00_18450	ENOG4105CEY	Amp-dependent synthetase and ligase
HZZ00_18460	ENOG4106A3M	Cytochrome p-450
HZZ00_18600	ENOG4105EAH	synthase
HZZ00_19080	ENOG4105VEQ	Cold shock protein
HZZ00_19175	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HZZ00_19280	ENOG4107QX9	Thiol disulfide interChange protein
HZZ00_19305	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_19360	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HZZ00_19420	ENOG4105CPC	Aldo Keto reductase
HZZ00_19425	ENOG4105EBR	Carboxylesterase
HZZ00_19430	ENOG4107U32	Beta-lactamase domain protein
HZZ00_19450	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HZZ00_19455	ENOG4105CHR	reductase
HZZ00_19485	ENOG4107HP6	Transcriptional regulator
HZZ00_19520	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
HZZ00_19525	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
HZZ00_19530	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
HZZ00_19540	ENOG4105ERH	Fumarylacetoacetate hydrolase
HZZ00_19550	ENOG41061H0	Monooxygenase
HZZ00_19565	ENOG4105ERH	Fumarylacetoacetate hydrolase
HZZ00_19590	ENOG4105BZ1	(ABC) transporter
HZZ00_19610	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
HZZ00_19620	ENOG4105CHR	reductase
HZZ00_19640	ENOG4105EIP	mannose-6-phosphate isomerase
HZZ00_19650	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_19665	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
HZZ00_19670	ENOG4105EG2	ABC transporter, permease
HZZ00_19680	ENOG4105ECR	NmrA family
HZZ00_19685	ENOG4108W9Q	Endoglucanase (EC 3.2.1.4)
HZZ00_19705	ENOG4108KC1	acyl-Coa dehydrogenase
HZZ00_19710	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HZZ00_19735	ENOG4105CI2	imidazolone-5-propionate hydrolase
HZZ00_19740	ENOG4108UU4	oxidoreductase (Short chain dehydrogenase reductase family)
HZZ00_19760	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
HZZ00_19775	ENOG4108JGH	Tetr family transcriptional regulator
HZZ00_19785	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HZZ00_19805	ENOG4105ECY	inositol monophosphatase
HZZ00_19815	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
HZZ00_19830	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HZZ00_19835	ENOG4105DG6	mannose-6-phosphate isomerase
HZZ00_19845	ENOG4105C7K	acetolactate synthase
HZZ00_19850	ENOG4105CBC	glutamate synthase
HZZ00_19895	ENOG4105D9P	serine threonine protein kinase
HZZ00_19910	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
HZZ00_19930	ENOG4107RSM	transcriptional regulator
HZZ00_19945	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HZZ00_19950	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_19955	ENOG41062B0	ABC transporter, permease
HZZ00_19960	ENOG4107R9N	ABC transporter
HZZ00_19965	ENOG4105C2J	ABC transporter
HZZ00_19970	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
HZZ00_19990	ENOG4108IND	Tetr family transcriptional regulator
HZZ00_20000	ENOG4107RSM	transcriptional regulator
HZZ00_20015	ENOG4108HMN	Caspase domain
HZZ00_20025	ENOG4105D9G	High-affinity
HZZ00_20045	ENOG4108762	serine threonine protein kinase
HZZ00_20050	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
HZZ00_20055	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HZZ00_20065	ENOG4108IND	Tetr family transcriptional regulator
HZZ00_20070	ENOG4105DND	Transcriptional regulator
HZZ00_20085	ENOG4105F9V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
HZZ00_20125	ENOG4105EV4	Multidrug resistance protein mdtH
HZZ00_20140	ENOG4105U5Y	Transcriptional regulator
HZZ00_20145	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_20185	ENOG4105CHP	RNA polymerase
HZZ00_20190	ENOG4105GRZ	Ycii-related protein
HZZ00_20195	ENOG4105DXI	Major Facilitator superfamily
HZZ00_20205	ENOG4105CG3	alpha amylase, catalytic region
HZZ00_20215	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
HZZ00_20325	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
HZZ00_20345	ENOG4108YV4	Universal stress protein
HZZ00_20355	ENOG4105FDF	Could be involved in DNA repair (By similarity)
HZZ00_20360	ENOG4105D9P	serine threonine protein kinase
HZZ00_20365	ENOG4105D4M	Lactamase_B
HZZ00_20400	ENOG4105D74	hydrolase
HZZ00_20405	ENOG4105CY0	Metallo-Beta-Lactamase
HZZ00_20435	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HZZ00_20445	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HZZ00_20455	ENOG4107RSM	transcriptional regulator
HZZ00_20480	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
HZZ00_20500	ENOG4108KEZ	Dehydrogenase
HZZ00_20550	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HZZ00_20575	ENOG4105CPC	Aldo Keto reductase
HZZ00_20580	ENOG4105VUF	Transcriptional regulator
HZZ00_20585	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HZZ00_20590	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
HZZ00_20660	ENOG4105CV8	reductase
HZZ00_20665	ENOG4108I69	Glycosyl transferases group 1
HZZ00_20670	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
HZZ00_20680	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
HZZ00_20695	ENOG4105VUF	Transcriptional regulator
HZZ00_20760	ENOG4108YV4	Universal stress protein
HZZ00_20765	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HZZ00_20775	ENOG4105BZP	glycoside hydrolase 15-related
HZZ00_20780	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HZZ00_20785	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HZZ00_20805	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
HZZ00_20810	ENOG4107TPS	domain protein
HZZ00_20820	ENOG4107QWR	cellulase (EC 3.2.1.4)
HZZ00_20825	ENOG4105CYP	glycoside hydrolase, family
HZZ00_20830	ENOG41065HY	1,4-beta-cellobiosidase
HZZ00_20835	ENOG4106R7G	Glycoside hydrolase family 5
HZZ00_20840	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_20850	ENOG4105CSH	Transporter
HZZ00_20865	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HZZ00_20875	ENOG4105E1F	short-chain dehydrogenase reductase
HZZ00_20900	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HZZ00_20915	ENOG4105MKU	Transcriptional regulator
HZZ00_20940	ENOG4105FS7	Transcriptional regulator
HZZ00_20955	ENOG4107MMM	Anti-sigma-factor antagonist
HZZ00_20960	ENOG4105FUA	antagonist
HZZ00_20965	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
HZZ00_20990	ENOG4105CXN	decarboxylase
HZZ00_20995	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
HZZ00_21000	ENOG4105EGE	secreted protein
HZZ00_21005	ENOG4105ERR	inositol mono-phosphatase
HZZ00_21050	ENOG4106UDK	Cellulose-binding, family II
HZZ00_21070	ENOG4108KPJ	rna polymerase sigma factor
HZZ00_21080	ENOG4105F27	Major Facilitator
HZZ00_21135	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_21140	ENOG4105BZU	Histidine kinase
HZZ00_21170	ENOG4108ZJ4	polysaccharide deacetylase
HZZ00_21180	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HZZ00_21230	ENOG4107Y2X	deaminase
HZZ00_21235	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
HZZ00_21240	ENOG4107B2H	carbonic anhydrase
HZZ00_21245	ENOG4105DND	Transcriptional regulator
HZZ00_21255	ENOG4105BZP	glycoside hydrolase 15-related
HZZ00_21270	ENOG4105D9G	High-affinity
HZZ00_21285	ENOG4105DQR	SNARE associated Golgi
HZZ00_21290	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HZZ00_21305	ENOG4107RUZ	Sss sodium solute transporter superfamily
HZZ00_21315	ENOG4105EQX	glucarate dehydratase
HZZ00_21325	ENOG4105E9Z	Nad-dependent epimerase dehydratase
HZZ00_21405	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_21410	ENOG41067SE	Tetr family transcriptional regulator
HZZ00_21430	ENOG4105C87	Aminotransferase class I and II
HZZ00_21455	ENOG4108W5M	transcriptional regulator
HZZ00_21465	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HZZ00_21495	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HZZ00_21520	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HZZ00_21570	ENOG4105EUB	pirin domain protein
HZZ00_21575	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HZZ00_21580	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HZZ00_21585	ENOG4107RDB	Major Facilitator
HZZ00_21590	ENOG41082JN	Transcriptional regulator
HZZ00_21605	ENOG4108W6C	Dehydrogenase
HZZ00_21615	ENOG4105CQB	FAD linked oxidase domain protein
HZZ00_21625	ENOG4105D3W	isochorismatase
HZZ00_21655	ENOG4108JJA	ABC, transporter
HZZ00_21685	ENOG4105EMU	Dehydrogenase
HZZ00_21705	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HZZ00_21720	ENOG4105DMF	Dehydrogenase
HZZ00_21750	ENOG4108V5V	Serine Threonine protein kinase
HZZ00_21770	ENOG4105CPC	Aldo Keto reductase
HZZ00_21800	ENOG4106YKD	Cytochrome p-450
HZZ00_21815	ENOG4105PGM	cation diffusion facilitator family transporter
HZZ00_21820	ENOG4105CHF	Glutathione S-transferase
HZZ00_21850	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HZZ00_21860	ENOG4105C8S	subunit m
HZZ00_21900	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HZZ00_21905	ENOG4105DCG	PHP domain protein
HZZ00_21910	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HZZ00_21935	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HZZ00_21960	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HZZ00_21970	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
HZZ00_21975	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HZZ00_21980	ENOG4105DDN	Pentapeptide repeat-containing protein
HZZ00_21985	ENOG4105E2A	Dehydrogenase
HZZ00_22005	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HZZ00_22010	ENOG4107QR9	Iron-sulfur cluster binding protein
HZZ00_22015	ENOG41080R8	Conserved Protein
HZZ00_22020	ENOG4105CHR	reductase
HZZ00_22040	ENOG4108IJ8	ABC transporter
HZZ00_22055	ENOG4105E90	ABC transporter
HZZ00_22070	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HZZ00_22100	ENOG4105EUB	pirin domain protein
HZZ00_22145	ENOG4105CIR	epoxide hydrolase
HZZ00_22155	ENOG41085A6	mbth domain-containing protein
HZZ00_22175	ENOG4106A3M	Cytochrome p-450
HZZ00_22195	ENOG4108R85	Short chain dehydrogenase
HZZ00_22240	ENOG4105DSG	hydrolase family 43
HZZ00_22265	ENOG4108762	serine threonine protein kinase
HZZ00_22270	ENOG4105BZU	Histidine kinase
HZZ00_22300	ENOG41066UM	arsR family transcriptional regulator
HZZ00_22310	ENOG410880H	cysteine synthase
HZZ00_22320	ENOG4105G6Z	alkaline phosphatase
HZZ00_22350	ENOG4106YKD	Cytochrome p-450
HZZ00_22435	ENOG4105CEY	Amp-dependent synthetase and ligase
HZZ00_22440	ENOG4105C7B	Threonine dehydratase
HZZ00_22455	ENOG4105WQT	MbtH domain protein
HZZ00_22465	ENOG4105EC3	peptidase S51, dipeptidase E
HZZ00_22475	ENOG4108S01	response regulator
HZZ00_22500	ENOG4106A3M	Cytochrome p-450
HZZ00_22515	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HZZ00_22525	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HZZ00_22530	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HZZ00_22535	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HZZ00_22540	ENOG4105WQT	MbtH domain protein
HZZ00_22615	ENOG4108MXC	l-carnitine dehydratase bile acid-inducible protein F
HZZ00_22620	ENOG4105CEY	Amp-dependent synthetase and ligase
HZZ00_22625	ENOG4105DYW	oxidoreductase
HZZ00_22630	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_22635	ENOG4105BZU	Histidine kinase
HZZ00_22690	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HZZ00_22695	ENOG41083TI	Protein CrcB homolog
HZZ00_22700	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
HZZ00_22735	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
HZZ00_22750	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HZZ00_22765	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
HZZ00_22785	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HZZ00_22805	ENOG4105E2R	ROK family
HZZ00_22810	ENOG4105F27	Major Facilitator
HZZ00_22815	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HZZ00_22830	ENOG4108HWW	ABC transporter
HZZ00_22835	ENOG4105C2J	ABC transporter
HZZ00_22840	ENOG4105DFW	ABC transporter
HZZ00_22845	ENOG4105CIR	epoxide hydrolase
HZZ00_22855	ENOG41080RH	Thioredoxin
HZZ00_22860	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_22905	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
HZZ00_22925	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
HZZ00_22930	ENOG4108V75	Glutamine amidotransferase
HZZ00_22935	ENOG41067HS	methyltransferase
HZZ00_22945	ENOG4105WKW	Pfam:DUF1458
HZZ00_22955	ENOG4105DEN	Luciferase family
HZZ00_22990	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
HZZ00_23000	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
HZZ00_23005	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
HZZ00_23010	ENOG4105IKQ	hydratase
HZZ00_23015	ENOG4108FUF	Transcriptional regulator, IclR family
HZZ00_23020	ENOG4105E33	succinate dehydrogenase
HZZ00_23035	ENOG4105C5Q	Transcriptional regulator
HZZ00_23040	ENOG4105BZU	Histidine kinase
HZZ00_23080	ENOG4105CRK	lysyL-tRNA synthetase
HZZ00_23100	ENOG4105CUB	amino acid
HZZ00_23140	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HZZ00_23185	ENOG4105CWX	Alpha-1,2-mannosidase
HZZ00_23205	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HZZ00_23210	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HZZ00_23220	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
HZZ00_23240	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_23245	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
HZZ00_23275	ENOG4105DIA	mandelate racemase muconate lactonizing
HZZ00_23295	ENOG4105BZP	glycoside hydrolase 15-related
HZZ00_23325	ENOG4107V2S	Transcriptional regulator
HZZ00_23330	ENOG4105KF0	sporulation and cell division protein, SsgA
HZZ00_23335	ENOG4105EQ0	Major Facilitator superfamily
HZZ00_23340	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
HZZ00_23460	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HZZ00_23480	ENOG4107RSM	transcriptional regulator
HZZ00_23495	ENOG4106A3M	Cytochrome p-450
HZZ00_23500	ENOG4107QKG	PfaD family
HZZ00_23505	ENOG4105C0W	non-ribosomal peptide synthetase
HZZ00_23520	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HZZ00_23535	ENOG4107SQU	synthase
HZZ00_23545	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
HZZ00_23570	ENOG4105C32	Amino acid ABC transporter (Permease)
HZZ00_23575	ENOG4108IV0	ABC, transporter
HZZ00_23580	ENOG4105C0Z	ABC transporter
HZZ00_23610	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HZZ00_23625	ENOG4105C0W	non-ribosomal peptide synthetase
HZZ00_23640	ENOG4107RCI	amp-dependent synthetase and ligase
HZZ00_23645	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HZZ00_23655	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
HZZ00_23660	ENOG4108IPT	Naphthoate synthase
HZZ00_23680	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
HZZ00_23705	ENOG4105C7W	Xanthine dehydrogenase
HZZ00_23710	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
HZZ00_23715	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
HZZ00_23720	ENOG4105BZ1	(ABC) transporter
HZZ00_23730	ENOG41060WC	Enoyl-CoA hydratase
HZZ00_23750	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HZZ00_23760	ENOG4105CUB	amino acid
HZZ00_23765	ENOG4105D64	Mechanosensitive ion channel
HZZ00_23770	ENOG4105M0C	cytoplasmic protein
HZZ00_23775	ENOG4105E9K	Isocitrate dehydrogenase
HZZ00_23790	ENOG4105DWV	Homoserine O-trans-acetylase
HZZ00_23800	ENOG4106A3M	Cytochrome p-450
HZZ00_23845	ENOG4108KQ5	Integrase catalytic subunit
HZZ00_23880	ENOG4105EAB	amino acid AbC transporter
HZZ00_23885	ENOG4105CDA	abc transporter atp-binding protein
HZZ00_23890	ENOG4105DRP	amino acid AbC transporter
HZZ00_23910	ENOG4105D5Q	Arginine ornithine antiporter
HZZ00_23915	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
HZZ00_23920	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_23925	ENOG4105ENE	Histidine kinase
HZZ00_24115	ENOG4108N6D	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HZZ00_24130	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
HZZ00_24160	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_24165	ENOG41089GP	Oxidoreductase domain protein
HZZ00_24180	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HZZ00_24190	ENOG4105C2J	ABC transporter
HZZ00_24195	ENOG4105CNN	ABC, transporter
HZZ00_24230	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_24250	ENOG4105KVH	Transcriptional regulator
HZZ00_24290	ENOG4105CEY	Amp-dependent synthetase and ligase
HZZ00_24300	ENOG4105E5G	Alpha beta hydrolase fold
HZZ00_24320	ENOG4108HCJ	Hydrolase
HZZ00_24415	ENOG4106NZI	LysR family Transcriptional regulator
HZZ00_24420	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HZZ00_24425	ENOG4105CPQ	Dehydrogenase
HZZ00_24460	ENOG41090WU	lipolytic protein G-D-S-L family
HZZ00_24490	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HZZ00_24495	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HZZ00_24520	ENOG4107S11	squalene-associated FAD-dependent desaturase
HZZ00_24530	ENOG4105FBD	synthase
HZZ00_24535	ENOG4105EY8	ABC transporter
HZZ00_24555	ENOG4108MDK	Dehydrogenase
HZZ00_24580	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
HZZ00_24595	ENOG41060WC	Enoyl-CoA hydratase
HZZ00_24610	ENOG4105BZM	domain protein
HZZ00_24615	ENOG4105C5H	ABC transporter
HZZ00_24635	ENOG4107R3J	Transporter
HZZ00_24645	ENOG4107QZF	nitrite reductase NADPH large subunit
HZZ00_24650	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HZZ00_24655	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HZZ00_24660	ENOG4107NHD	transcriptional regulator
HZZ00_24685	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HZZ00_24690	ENOG4105CHU	acetyl-coa acetyltransferase
HZZ00_24695	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HZZ00_24710	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
HZZ00_24730	ENOG4105KF0	sporulation and cell division protein, SsgA
HZZ00_24735	ENOG4105C5H	ABC transporter
HZZ00_24740	ENOG4106V2I	dimethylaminohydrolase
HZZ00_24750	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
HZZ00_24760	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_24765	ENOG4105DQE	DNA ligase
HZZ00_24850	ENOG4105F8D	glycoside hydrolase family 4
HZZ00_24875	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HZZ00_24890	ENOG4107QP8	phosphohexose isomerase
HZZ00_24895	ENOG4108J5G	6-phosphogluconate dehydrogenase
HZZ00_24900	ENOG4108ZM9	phosphoglycerate mutase
HZZ00_24920	ENOG410905P	Pyridoxamine 5-phosphate
HZZ00_24965	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HZZ00_24980	ENOG4105C28	cystathionine
HZZ00_24985	ENOG4105ETS	cytosine purines uracil thiamine allantoin
HZZ00_25000	ENOG4108HRK	Histidine kinase
HZZ00_25005	ENOG4108NEV	two component transcriptional regulator, LytTR family
HZZ00_25020	ENOG4106HK8	GPR1 FUN34 yaaH family protein
HZZ00_25025	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HZZ00_25040	ENOG41069M3	Transcriptional regulator
HZZ00_25050	ENOG4106N3A	copper homeostasis protein cutc
HZZ00_25060	ENOG4105E2R	ROK family
HZZ00_25065	ENOG4105DEF	Extracellular solute-binding protein, family 5
HZZ00_25100	ENOG4106A3M	Cytochrome p-450
HZZ00_25135	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HZZ00_25140	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HZZ00_25155	ENOG4105DHU	Bile acid
HZZ00_25160	ENOG4107V2S	Transcriptional regulator
HZZ00_25170	ENOG4105CV8	reductase
HZZ00_25185	ENOG4105EMU	Dehydrogenase
HZZ00_25200	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
HZZ00_25205	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HZZ00_25210	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HZZ00_25220	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HZZ00_25225	ENOG4106GCT	Dehydratase
HZZ00_25295	ENOG4108Z0Z	intracellular protease Pfpi family
HZZ00_25310	ENOG4105C5H	ABC transporter
HZZ00_25335	ENOG4105W2E	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth (By similarity)
HZZ00_25345	ENOG4105W2E	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth (By similarity)
HZZ00_25370	ENOG4105MRC	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth
HZZ00_25415	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
HZZ00_25425	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HZZ00_25430	ENOG4108ME1	Peptidase M55 D-aminopeptidase
HZZ00_25440	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HZZ00_25445	ENOG4108Q50	Histidine kinase
HZZ00_25505	ENOG4105EYF	MMPL domain protein
HZZ00_25520	ENOG4105EA8	2-Nitropropane dioxygenase
HZZ00_25525	ENOG4105CHU	acetyl-coa acetyltransferase
HZZ00_25530	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HZZ00_25535	ENOG4105E39	Enoyl-CoA hydratase
HZZ00_25545	ENOG4105D2B	acyl-CoA dehydrogenase
HZZ00_25550	ENOG4105D2B	acyl-CoA dehydrogenase
HZZ00_25580	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HZZ00_25590	ENOG4105J7D	transcriptional regulator
HZZ00_25610	ENOG4105FP9	thiamine pyrophosphate
HZZ00_25620	ENOG4107RGH	Aldehyde dehydrogenase
HZZ00_25630	ENOG4108UKI	Enoyl-CoA hydratase
HZZ00_25640	ENOG4105CHU	acetyl-coa acetyltransferase
HZZ00_25685	ENOG4106JDR	secreted
HZZ00_25695	ENOG4107U9T	Pfam:Ribonuclease_BN
HZZ00_25710	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HZZ00_25730	ENOG4105CI0	Citrate lyase
HZZ00_25740	ENOG4105C1G	acyl-Coa dehydrogenase
HZZ00_25745	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
HZZ00_25755	ENOG4105BZW	Glycerate kinase
HZZ00_25770	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HZZ00_25785	ENOG4105DAE	Methylenetetrahydrofolate reductase
HZZ00_25795	ENOG4106A3M	Cytochrome p-450
HZZ00_25800	ENOG4106A3M	Cytochrome p-450
HZZ00_25830	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HZZ00_25845	ENOG4105ECY	inositol monophosphatase
HZZ00_25895	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
HZZ00_25905	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
HZZ00_25920	ENOG4105C8Y	Acetylornithine aminotransferase
HZZ00_25935	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HZZ00_25940	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HZZ00_25955	ENOG4105CGK	Exodeoxyribonuclease III
HZZ00_25965	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
HZZ00_25970	ENOG4105CGD	Nad-dependent epimerase dehydratase
HZZ00_25975	ENOG4107RTG	Major Facilitator superfamily
HZZ00_25995	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HZZ00_26030	ENOG4105CPN	adenine deaminase
HZZ00_26035	ENOG4105CHJ	isochorismatase hydrolase
HZZ00_26040	ENOG4108VGI	doxx family
HZZ00_26045	ENOG4105XPP	Protein of unknown function (DUF1275)
HZZ00_26050	ENOG4107SFI	Major Facilitator superfamily
HZZ00_26055	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
HZZ00_26060	ENOG4108UZX	fmn reductase
HZZ00_26065	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
HZZ00_26075	ENOG4105C7K	acetolactate synthase
HZZ00_26115	ENOG41082YX	Transcriptional regulator, arsr family
HZZ00_26120	ENOG41089UC	methyltransferase, type 11
HZZ00_26135	ENOG4105VPX	protein, conserved in bacteria
HZZ00_26145	ENOG4108VCT	Sulfite exporter TauE/SafE
HZZ00_26155	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HZZ00_26160	ENOG4107RDB	Major Facilitator
HZZ00_26180	ENOG4105C0D	helicase
HZZ00_26190	ENOG4105DKQ	ROK family
HZZ00_26195	ENOG4105C2J	ABC transporter
HZZ00_26200	ENOG41062B0	ABC transporter, permease
HZZ00_26215	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HZZ00_26245	ENOG4105DHG	Allantoate amidinohydrolase
HZZ00_26255	ENOG4107HP6	Transcriptional regulator
HZZ00_26270	ENOG4107R9S	Malate synthase
HZZ00_26280	ENOG4105K4I	Scp-like extracellular
HZZ00_26290	ENOG4105DUU	IucA IucC family protein
HZZ00_26310	ENOG4105CHM	Aminotransferase
HZZ00_26320	ENOG4108ZM9	phosphoglycerate mutase
HZZ00_26335	ENOG4105C2W	permease
HZZ00_26340	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HZZ00_26350	ENOG4105VT2	5-hydroxyisourate hydrolase
HZZ00_26370	ENOG4107TFQ	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
HZZ00_26375	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HZZ00_26380	ENOG4105CH6	catalase
HZZ00_26395	ENOG41060W2	glyoxylate carboligase
HZZ00_26405	ENOG4105CEY	Amp-dependent synthetase and ligase
HZZ00_26410	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HZZ00_26425	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
HZZ00_26435	ENOG4106NZI	LysR family Transcriptional regulator
HZZ00_26445	ENOG4105EPJ	extracellular solute-binding protein family 1
HZZ00_26460	ENOG4107Q25	Serine Threonine protein kinase
HZZ00_26470	ENOG4108ZJ4	polysaccharide deacetylase
HZZ00_26480	ENOG410829K	Lysine exporter protein (Lyse ygga)
HZZ00_26490	ENOG4105C7N	Xanthine uracil vitamin C permease
HZZ00_26495	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
HZZ00_26525	ENOG4105DRR	Transcriptional regulator, GntR family
HZZ00_26540	ENOG4105C7K	acetolactate synthase
HZZ00_26560	ENOG4108JNI	Alpha beta hydrolase
HZZ00_26570	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HZZ00_26585	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HZZ00_26590	ENOG4108W9Q	Endoglucanase (EC 3.2.1.4)
HZZ00_26605	ENOG4105QE3	oxidoreductase
HZZ00_26630	ENOG4108J5H	Homocysteine s-methyltransferase
HZZ00_26635	ENOG4105EBR	Carboxylesterase
HZZ00_26645	ENOG4105CR4	methylisocitrate lyase
HZZ00_26675	ENOG4105CSU	acyl-Coa dehydrogenase
HZZ00_26680	ENOG4107RR1	TRANSCRIPTIONal
HZZ00_26690	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
HZZ00_26705	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HZZ00_26735	ENOG4108IY8	ABC, transporter
HZZ00_26755	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HZZ00_26795	ENOG4105DND	Transcriptional regulator
HZZ00_26845	ENOG4105IK6	Terpene synthase metal-binding domain-containing protein
HZZ00_26865	ENOG41064MX	Tetr family transcriptional regulator
HZZ00_26890	ENOG4108HQR	Glycine betaine
HZZ00_26895	ENOG4105E90	ABC transporter
HZZ00_26900	ENOG4105E90	ABC transporter
HZZ00_26905	ENOG4108IJ8	ABC transporter
HZZ00_26910	ENOG4105E0X	reductase
HZZ00_26915	ENOG4105DFU	Cell wall formation (By similarity)
HZZ00_26935	ENOG4107B2H	carbonic anhydrase
HZZ00_26955	ENOG4108TKH	Nitroreductase
HZZ00_26965	ENOG4105CSR	polyphosphate kinase 2
HZZ00_26975	ENOG4108NMV	polysaccharide deacetylase
HZZ00_26985	ENOG4108IUX	(ABC) transporter
HZZ00_26995	ENOG4105E18	UPF0276 protein
HZZ00_27010	ENOG4107JTW	chlorite dismutase
HZZ00_27020	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
HZZ00_27040	ENOG4105KF0	sporulation and cell division protein, SsgA
HZZ00_27045	ENOG4105F0K	SARP family transcriptional regulator
HZZ00_27065	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HZZ00_27080	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
HZZ00_27085	ENOG4105CHU	acetyl-coa acetyltransferase
HZZ00_27090	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HZZ00_27105	ENOG4105CUB	amino acid
HZZ00_27110	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HZZ00_27115	ENOG4108HWW	ABC transporter
HZZ00_27120	ENOG4105C2J	ABC transporter
HZZ00_27125	ENOG4105DFW	ABC transporter
HZZ00_27130	ENOG4105E2R	ROK family
HZZ00_27140	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
HZZ00_27155	ENOG41080R8	Conserved Protein
HZZ00_27165	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HZZ00_27170	ENOG4105DAA	L-lactate
HZZ00_27175	ENOG4105C6F	GntR Family Transcriptional Regulator
HZZ00_27180	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
HZZ00_27185	ENOG4107QM5	aconitate hydratase
HZZ00_27200	ENOG4105EW9	transcriptional regulator AsnC family
HZZ00_27205	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HZZ00_27260	ENOG4105D17	glycoside hydrolase, family 3 domain protein
HZZ00_27280	ENOG4105FDP	GntR family transcriptional regulator
HZZ00_27295	ENOG4107TE5	Lipid kinase
HZZ00_27360	ENOG4105C8Y	Acetylornithine aminotransferase
HZZ00_27385	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HZZ00_27390	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HZZ00_27405	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HZZ00_27410	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HZZ00_27415	ENOG4108Z4U	Ferredoxin
HZZ00_27450	ENOG4105D8K	carboxyl transferase
HZZ00_27460	ENOG4108KQ5	Integrase catalytic subunit
HZZ00_27495	ENOG4105CGU	Enoyl-CoA hydratase
HZZ00_27505	ENOG4105CUB	amino acid
HZZ00_27510	ENOG4105DBV	ornithine carbamoyltransferase
HZZ00_27515	ENOG4105CEU	Arginine dihydrolase
HZZ00_27525	ENOG4107S1Q	Phosphatase
HZZ00_27530	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HZZ00_27535	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
HZZ00_27605	ENOG4105FS7	Transcriptional regulator
HZZ00_27675	ENOG4105CHR	reductase
HZZ00_27740	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HZZ00_27755	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_27780	ENOG4105ERH	Fumarylacetoacetate hydrolase
HZZ00_27795	ENOG4105CPF	Cell wall formation (By similarity)
HZZ00_27850	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
HZZ00_27855	ENOG4105BZ1	(ABC) transporter
HZZ00_27860	ENOG4108JJB	ABC transporter
HZZ00_27870	ENOG4105EX0	alpha-galactosidase
HZZ00_27895	ENOG4108V5V	Serine Threonine protein kinase
HZZ00_27920	ENOG41086VY	Fic/DOC family
HZZ00_27930	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HZZ00_27935	ENOG4105C0X	amino acid
HZZ00_27940	ENOG4107VEG	TrkA-N domain protein
HZZ00_27970	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HZZ00_27980	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HZZ00_28005	ENOG4106F60	Histidine kinase
HZZ00_28010	ENOG4105F44	Two component transcriptional regulator, winged helix family
HZZ00_28025	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HZZ00_28050	ENOG4105KHC	sulfurtransferase
HZZ00_28060	ENOG4107W53	thymidine kinase
HZZ00_28080	ENOG410849S	phosphocarrier protein (HPr)
HZZ00_28085	ENOG4105DRR	Transcriptional regulator, GntR family
HZZ00_28105	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HZZ00_28115	ENOG4105BZN	citrate synthase
HZZ00_28120	ENOG4105BZN	citrate synthase
HZZ00_28140	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HZZ00_28150	ENOG4108MRH	transcriptional regulatory protein
HZZ00_28155	ENOG4108KQ5	Integrase catalytic subunit
HZZ00_28160	ENOG4107QN1	sodium solute
HZZ00_28170	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_28185	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HZZ00_28195	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
HZZ00_28210	ENOG4105DRR	Transcriptional regulator, GntR family
HZZ00_28235	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HZZ00_28250	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HZZ00_28260	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HZZ00_28275	ENOG4105CEY	Amp-dependent synthetase and ligase
HZZ00_28285	ENOG4105DQU	oxidoreductase, subunit beta
HZZ00_28290	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
HZZ00_28295	ENOG4105DJI	Methylaspartate mutase, E subunit
HZZ00_28330	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HZZ00_28345	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HZZ00_28350	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HZZ00_28355	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HZZ00_28385	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HZZ00_28395	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HZZ00_28400	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HZZ00_28410	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HZZ00_28430	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HZZ00_28450	ENOG4105H1G	trap transporter solute receptor taxi family
HZZ00_28455	ENOG4105EB3	Histidine kinase
HZZ00_28460	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HZZ00_28465	ENOG4105CDA	abc transporter atp-binding protein
HZZ00_28470	ENOG4107UBR	Extracellular solute-binding protein family 3
HZZ00_28475	ENOG4108Q1T	ABC transporter
HZZ00_28480	ENOG4105DRP	amino acid AbC transporter
HZZ00_28485	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
HZZ00_28495	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HZZ00_28535	ENOG4106AXJ	AraC family transcriptional regulator
HZZ00_28540	ENOG4107QRT	dEAD DEAH box helicase
HZZ00_28545	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
HZZ00_28560	ENOG4105WBV	Transcriptional regulator
HZZ00_28565	ENOG4105CEV	competence damage-inducible protein
HZZ00_28575	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HZZ00_28590	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HZZ00_28630	ENOG4105CN5	Metallo-Beta-Lactamase
HZZ00_28635	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HZZ00_28640	ENOG4107V6K	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
HZZ00_28660	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HZZ00_28665	ENOG4105C1V	Peptidase, M16
HZZ00_28670	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HZZ00_28675	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HZZ00_28695	ENOG4105EC2	ftsk spoIIIe
HZZ00_28760	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HZZ00_28765	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HZZ00_28775	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HZZ00_28790	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
HZZ00_28805	ENOG4105NFX	aminoglycoside hydroxyurea antibiotic resistance kinase
HZZ00_28810	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HZZ00_28825	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HZZ00_28830	ENOG4105DZP	Membrane-associated zinc metalloprotease
HZZ00_28835	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HZZ00_28915	ENOG4105CJP	fad dependent oxidoreductase
HZZ00_28920	ENOG4105D38	putrescine abc transporter
HZZ00_28925	ENOG4105F38	ABC transporter, permease
HZZ00_28930	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HZZ00_28940	ENOG4105C26	Dehydrogenase
HZZ00_28955	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HZZ00_28960	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HZZ00_28985	ENOG4105EHZ	conserved protein UCP016719
HZZ00_29030	ENOG4105C26	Dehydrogenase
HZZ00_29040	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HZZ00_29045	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HZZ00_29070	ENOG4108UCS	ABC, transporter
HZZ00_29075	ENOG4105ECW	sulfate abc transporter
HZZ00_29085	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HZZ00_29095	ENOG4105DQ4	alcohol dehydrogenase
HZZ00_29105	ENOG4105KNE	Phosphatidate cytidylyltransferase
HZZ00_29115	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HZZ00_29120	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HZZ00_29125	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HZZ00_29130	ENOG4105CE9	30S ribosomal protein S2
HZZ00_29145	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HZZ00_29160	ENOG41080R2	UPF0102 protein
HZZ00_29180	ENOG4107QYR	Signal peptidase i
HZZ00_29190	ENOG4105C3F	Signal peptidase i
HZZ00_29195	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HZZ00_29200	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HZZ00_29205	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HZZ00_29210	ENOG41082KU	UPF0109 protein
HZZ00_29215	ENOG4105K5M	30s ribosomal protein S16
HZZ00_29225	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HZZ00_29230	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HZZ00_29240	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HZZ00_29270	ENOG4105ETS	cytosine purines uracil thiamine allantoin
HZZ00_29285	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HZZ00_29295	ENOG4108375	Acylphosphatase (EC 3.6.1.7)
HZZ00_29310	ENOG4105KVH	Transcriptional regulator
HZZ00_29315	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HZZ00_29320	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HZZ00_29325	ENOG41084BZ	50S ribosomal protein L32
HZZ00_29340	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HZZ00_29345	ENOG4106H78	methyltransferase
HZZ00_29355	ENOG4105DP4	dak2 domain fusion protein ylov
HZZ00_29360	ENOG4105VB9	50S ribosomal protein l28
HZZ00_29365	ENOG4105DWF	phosphomethylpyrimidine kinase
HZZ00_29385	ENOG4105CPF	Cell wall formation (By similarity)
HZZ00_29390	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HZZ00_29410	ENOG4105K70	DNA-binding protein
HZZ00_29420	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HZZ00_29425	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HZZ00_29430	ENOG41069M3	Transcriptional regulator
HZZ00_29475	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HZZ00_29480	ENOG4105ERH	Fumarylacetoacetate hydrolase
HZZ00_29500	ENOG4105GWZ	Roadblock lc7 family protein
HZZ00_29520	ENOG4105GWZ	Roadblock lc7 family protein
HZZ00_29540	ENOG4105D8K	carboxyl transferase
HZZ00_29545	ENOG4108YYC	ycei family
HZZ00_29560	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
HZZ00_29575	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HZZ00_29580	ENOG4105CSH	Transporter
HZZ00_29595	ENOG4105DWY	Agmatine deiminase
HZZ00_29600	ENOG4105CQM	Urea amidohydrolase subunit alpha
HZZ00_29610	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HZZ00_29615	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HZZ00_29625	ENOG4105C26	Dehydrogenase
HZZ00_29635	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
HZZ00_29660	ENOG4105C57	major facilitator superfamily
HZZ00_29665	ENOG4108JQ1	Dehydrogenase
HZZ00_29670	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HZZ00_29675	ENOG4108ZP8	Acetolactate synthase small subunit
HZZ00_29685	ENOG4105BZU	Histidine kinase
HZZ00_29695	ENOG4105CPC	Aldo Keto reductase
HZZ00_29710	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_29725	ENOG4105D9U	N-acetyltransferase
HZZ00_29730	ENOG4105EYF	MMPL domain protein
HZZ00_29735	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HZZ00_29745	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HZZ00_29750	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HZZ00_29765	ENOG4105BZU	Histidine kinase
HZZ00_29770	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HZZ00_29780	ENOG4105EMU	Dehydrogenase
HZZ00_29800	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HZZ00_29825	ENOG4105D29	Helix-turn-helix type 11 domain protein
HZZ00_29845	ENOG4105EN6	Membrane
HZZ00_29855	ENOG4108JQ7	(ABC) transporter
HZZ00_29865	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HZZ00_29875	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HZZ00_29895	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HZZ00_29900	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HZZ00_29905	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HZZ00_29910	ENOG4105EJQ	L-serine dehydratase
HZZ00_29920	ENOG4105KVH	Transcriptional regulator
HZZ00_29925	ENOG4107YXZ	hydrolase, family 25
HZZ00_29960	ENOG4105E39	Enoyl-CoA hydratase
HZZ00_29970	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
HZZ00_29990	ENOG4105CND	Glycosyl transferase, family 2
HZZ00_30005	ENOG4105BZ1	(ABC) transporter
HZZ00_30010	ENOG4105BZ1	(ABC) transporter
HZZ00_30015	ENOG4105CJ1	ABC, transporter
HZZ00_30025	ENOG4105BZU	Histidine kinase
HZZ00_30030	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_30035	ENOG4105BZ1	(ABC) transporter
HZZ00_30040	ENOG4105BZ1	(ABC) transporter
HZZ00_30060	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
HZZ00_30065	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
HZZ00_30075	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
HZZ00_30080	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HZZ00_30090	ENOG4105C3M	thioredoxin reductase
HZZ00_30095	ENOG4108Z6Z	Transcriptional regulator
HZZ00_30105	ENOG4105C57	major facilitator superfamily
HZZ00_30115	ENOG4107QJT	sodium dicarboxylate symporter
HZZ00_30120	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
HZZ00_30125	ENOG4108MRH	transcriptional regulatory protein
HZZ00_30145	ENOG4105CTQ	phosphohexokinase
HZZ00_30150	ENOG4105C6K	Malic enzyme
HZZ00_30155	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HZZ00_30195	ENOG4105WX6	Membrane
HZZ00_30255	ENOG4105CHU	acetyl-coa acetyltransferase
HZZ00_30275	ENOG4105CJ1	ABC, transporter
HZZ00_30300	ENOG4108M8W	Monooxygenase
HZZ00_30310	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
HZZ00_30315	ENOG4107RSM	transcriptional regulator
HZZ00_30325	ENOG4105C2C	drug resistance transporter, Bcr CflA
HZZ00_30355	ENOG4105C84	Histidine ammonia-lyase
HZZ00_30375	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HZZ00_30385	ENOG410630P	Transcriptional regulator
HZZ00_30405	ENOG4105IIP	Membrane
HZZ00_30410	ENOG4105BZU	Histidine kinase
HZZ00_30415	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_30430	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HZZ00_30435	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HZZ00_30440	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HZZ00_30445	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HZZ00_30450	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HZZ00_30455	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
HZZ00_30460	ENOG4105ZA1	atp synthase
HZZ00_30470	ENOG4105Z3P	ATP synthase
HZZ00_30475	ENOG4105ESV	Glycosyl transferase, family 4
HZZ00_30480	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HZZ00_30485	ENOG4107ZF2	Phosphatase
HZZ00_30495	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HZZ00_30500	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HZZ00_30505	ENOG4105VFB	Binds the 23S rRNA (By similarity)
HZZ00_30520	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HZZ00_30525	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
HZZ00_30530	ENOG4105D6E	homoserine dehydrogenase
HZZ00_30535	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HZZ00_30540	ENOG4105C75	arginyL-tRNA synthetase
HZZ00_30540	ENOG4105C75	arginyL-tRNA synthetase
HZZ00_30630	ENOG4105CE1	Ferrous iron transport protein b
HZZ00_30670	ENOG4105FDF	Could be involved in DNA repair (By similarity)
HZZ00_30675	ENOG4105DQE	DNA ligase
HZZ00_30695	ENOG4108FKE	two-component system sensor kinase
HZZ00_30705	ENOG4105CJN	penicillin-binding protein
HZZ00_30730	ENOG41090B9	response to stress
HZZ00_30790	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HZZ00_30805	ENOG4108PYU	two-component system response regulator
HZZ00_30810	ENOG4105EB3	Histidine kinase
HZZ00_30815	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HZZ00_30835	ENOG4105CB2	alcohol dehydrogenase
HZZ00_30840	ENOG4105C6K	Malic enzyme
HZZ00_30855	ENOG4105CDA	abc transporter atp-binding protein
HZZ00_30860	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HZZ00_30875	ENOG4108VEQ	Superoxide dismutase
HZZ00_30905	ENOG4105K6H	D-cysteine desulfhydrase
HZZ00_30920	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
HZZ00_30935	ENOG4105CBD	Diacylglycerol kinase
HZZ00_30950	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HZZ00_30955	ENOG4105FDP	GntR family transcriptional regulator
HZZ00_30975	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HZZ00_30980	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HZZ00_30995	ENOG41068W2	Cytochrome p-450
HZZ00_31005	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HZZ00_31015	ENOG4105WMN	AntiSigma factor
HZZ00_31020	ENOG4105EMN	RNA polymerase sigma factor
HZZ00_31030	ENOG4108RAV	Conserved protein
HZZ00_31040	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HZZ00_31045	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HZZ00_31050	ENOG4105KPY	Small multidrug resistance protein
HZZ00_31060	ENOG4107TK4	histidinol-phosphate phosphatase
HZZ00_31095	ENOG4105DJZ	UPF0182 protein
HZZ00_31105	ENOG41063PX	domain protein
HZZ00_31175	ENOG4105WBQ	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
HZZ00_31195	ENOG4105E09	nadh pyrophosphatase
HZZ00_31200	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HZZ00_31205	ENOG4105C4R	Atp-dependent dna helicase
HZZ00_31255	ENOG4108JQ6	ABC transporter
HZZ00_31265	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HZZ00_31270	ENOG4105DEF	Extracellular solute-binding protein, family 5
HZZ00_31310	ENOG4105C1J	atp-dependent rna helicase
HZZ00_31330	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HZZ00_31345	ENOG4105DXB	Major Facilitator superfamily
HZZ00_31355	ENOG4105D7N	magnesium and cobalt transport protein CorA
HZZ00_31390	ENOG410630M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HZZ00_31395	ENOG4105C0H	protease
HZZ00_31405	ENOG4105DU6	RNA polymerase
HZZ00_31420	ENOG4105CGU	Enoyl-CoA hydratase
HZZ00_31425	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HZZ00_31435	ENOG4105EEI	dihydropteroate synthase
HZZ00_31440	ENOG4108URH	decarboxylase
HZZ00_31445	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
HZZ00_31465	ENOG4108Z4U	Ferredoxin
HZZ00_31480	ENOG4108S01	response regulator
HZZ00_31485	ENOG4105BZU	Histidine kinase
HZZ00_31495	ENOG4108M15	ABC transporter
HZZ00_31525	ENOG4108JQ7	(ABC) transporter
HZZ00_31530	ENOG4105C3U	ABC transporter
HZZ00_31535	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HZZ00_31540	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HZZ00_31545	ENOG4108J59	Extracellular solute-binding protein, family 5
HZZ00_31550	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HZZ00_31555	ENOG4105DEF	Extracellular solute-binding protein, family 5
HZZ00_31570	ENOG4108JQ7	(ABC) transporter
HZZ00_31580	ENOG4108JQ7	(ABC) transporter
HZZ00_31595	ENOG4108J59	Extracellular solute-binding protein, family 5
HZZ00_31605	ENOG4105CI3	gtp-binding protein typa
HZZ00_31625	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HZZ00_31695	ENOG4105CJA	serine threonine protein kinase
HZZ00_31730	ENOG4105C0A	alcohol dehydrogenase
HZZ00_31735	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HZZ00_31750	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
HZZ00_31770	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HZZ00_31780	ENOG4108KXV	response regulator
HZZ00_31785	ENOG41065SU	Two-component system sensor kinase
HZZ00_31815	ENOG41089N3	Inherit from COG: cobyrinic Acid a,c-diamide synthase
HZZ00_31845	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HZZ00_31860	ENOG4105C3G	gtp-binding protein
HZZ00_31875	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HZZ00_31880	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HZZ00_31885	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HZZ00_31890	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
HZZ00_31905	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
HZZ00_31915	ENOG4107GFK	fumarate
HZZ00_31920	ENOG4105C9Q	fumarate hydratase class II
HZZ00_31935	ENOG4105BZ4	penicillin-binding protein
HZZ00_31945	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HZZ00_31960	ENOG4105D3R	alkyl hydroperoxide reductase
HZZ00_31965	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HZZ00_31980	ENOG4108IAB	Phoh family
HZZ00_31985	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HZZ00_31990	ENOG4105F2W	methyltransferase
HZZ00_32000	ENOG4107QKZ	Ompa motb domain protein
HZZ00_32015	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_32020	ENOG4105BZU	Histidine kinase
HZZ00_32050	ENOG4107QMS	site-determining protein
HZZ00_32085	ENOG4105C6Z	Gluconate
HZZ00_32090	ENOG4105KME	endoribonuclease L-psp
HZZ00_32095	ENOG4108FUF	Transcriptional regulator, IclR family
HZZ00_32125	ENOG4105CHM	Aminotransferase
HZZ00_32135	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
HZZ00_32140	ENOG4108UT2	hemolysin iii
HZZ00_32160	ENOG4105C7Z	Conserved Protein
HZZ00_32185	ENOG4105T1M	mycothiol conjugate amidase mca
HZZ00_32195	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HZZ00_32200	ENOG4105C7B	Threonine dehydratase
HZZ00_32240	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HZZ00_32245	ENOG4105DQ4	alcohol dehydrogenase
HZZ00_32255	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HZZ00_32285	ENOG4105C84	Histidine ammonia-lyase
HZZ00_32290	ENOG4105KDM	Diguanylate cyclase with gaf sensor
HZZ00_32295	ENOG4105E39	Enoyl-CoA hydratase
HZZ00_32305	ENOG4108QER	Adenylate cyclase
HZZ00_32315	ENOG4105D8K	carboxyl transferase
HZZ00_32325	ENOG4107WR6	Maf-like protein
HZZ00_32335	ENOG4108JIK	carboxylase
HZZ00_32365	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
HZZ00_32410	ENOG4105C26	Dehydrogenase
HZZ00_32415	ENOG4105C26	Dehydrogenase
HZZ00_32445	ENOG4105NAF	rna polymerase sigma factor
HZZ00_32450	ENOG4108KXV	response regulator
HZZ00_32455	ENOG41065SU	Two-component system sensor kinase
HZZ00_32480	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HZZ00_32490	ENOG4107RSM	transcriptional regulator
HZZ00_32495	ENOG4105D94	Major Facilitator Superfamily
HZZ00_32500	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HZZ00_32530	ENOG4105UIB	(ABC) transporter
HZZ00_32535	ENOG4108JQ9	ABC transporter
HZZ00_32540	ENOG4105DIH	basic membrane
HZZ00_32545	ENOG4107RM1	amidohydrolase
HZZ00_32585	ENOG4105D2T	synthase
HZZ00_32590	ENOG4105F0R	Cytidylyltransferase
HZZ00_32600	ENOG4105K64	Glycosyl transferase, family 2
HZZ00_32625	ENOG4108NIW	Leucine export protein LeuE
HZZ00_32640	ENOG4108MMM	RNA Polymerase
HZZ00_32670	ENOG4105E2D	ec 3.2.1.52
HZZ00_32690	ENOG4108J01	L-aspartate oxidase
HZZ00_32710	ENOG4108RZE	Tetr family transcriptional regulator
HZZ00_32730	ENOG4107H3J	ribonuclease
HZZ00_32745	ENOG4105C31	Tryptophanyl-tRNA synthetase
HZZ00_32750	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HZZ00_32760	ENOG4106032	Glutathionylspermidine synthase
HZZ00_32780	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HZZ00_32785	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HZZ00_32800	ENOG4108HQS	Glycine betaine
HZZ00_32805	ENOG4108IJ7	Glycine betaine
HZZ00_32820	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HZZ00_32835	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HZZ00_32845	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HZZ00_32875	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HZZ00_32880	ENOG4105DEG	Vwa containing coxe family protein
HZZ00_32890	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
HZZ00_32935	ENOG4105K4H	Nlp p60 protein
HZZ00_32940	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_32980	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HZZ00_32995	ENOG4105C26	Dehydrogenase
HZZ00_33000	ENOG4108UGD	Serine Threonine protein kinase
HZZ00_33005	ENOG4107U32	Beta-lactamase domain protein
HZZ00_33015	ENOG4108UGD	Serine Threonine protein kinase
HZZ00_33020	ENOG4107TPY	serine threonine protein kinase
HZZ00_33025	ENOG4105D9P	serine threonine protein kinase
HZZ00_33035	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HZZ00_33040	ENOG4107QQG	Dehydrogenase
HZZ00_33050	ENOG4107QVP	Dehydrogenase
HZZ00_33060	ENOG4108MMM	RNA Polymerase
HZZ00_33065	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_33070	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
HZZ00_33075	ENOG4105DND	Transcriptional regulator
HZZ00_33085	ENOG4105EMU	Dehydrogenase
HZZ00_33100	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HZZ00_33130	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_33135	ENOG4105XN3	extracellular solute-binding protein family 1
HZZ00_33140	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
HZZ00_33165	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HZZ00_33185	ENOG4108097	ATP-binding protein
HZZ00_33190	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
HZZ00_33195	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HZZ00_33210	ENOG4105CHR	reductase
HZZ00_33215	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HZZ00_33220	ENOG4105CS9	pantothenic acid kinase
HZZ00_33230	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HZZ00_33235	ENOG4108UJD	30S ribosomal protein S9
HZZ00_33240	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HZZ00_33250	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HZZ00_33255	ENOG4108ZT0	50S ribosomal protein l17
HZZ00_33260	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HZZ00_33265	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HZZ00_33270	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HZZ00_33275	ENOG41067V7	50S ribosomal protein L36
HZZ00_33280	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HZZ00_33290	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HZZ00_33300	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HZZ00_33305	ENOG410849U	50S ribosomal protein L30
HZZ00_33310	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HZZ00_33315	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HZZ00_33320	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HZZ00_33325	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HZZ00_33330	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HZZ00_33335	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HZZ00_33340	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HZZ00_33345	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HZZ00_33350	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HZZ00_33355	ENOG41082SA	50s ribosomal protein l29
HZZ00_33360	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HZZ00_33365	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HZZ00_33370	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HZZ00_33375	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HZZ00_33380	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HZZ00_33385	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HZZ00_33390	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HZZ00_33395	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HZZ00_33400	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HZZ00_33460	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HZZ00_33465	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HZZ00_33470	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HZZ00_33475	ENOG4105VP2	Transcriptional regulator, Crp Fnr family
HZZ00_33505	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HZZ00_33510	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HZZ00_33520	ENOG4108VZM	50s ribosomal protein L10
HZZ00_33530	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HZZ00_33540	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HZZ00_33560	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HZZ00_33565	ENOG4107R4N	Cell wall formation (By similarity)
HZZ00_33600	ENOG410900P	UPF0336 protein
HZZ00_33605	ENOG4105WDJ	50S ribosomal protein L33
HZZ00_33640	ENOG4105BZU	Histidine kinase
HZZ00_33690	ENOG4108VPT	UPF0234 protein
HZZ00_33695	ENOG4105Y3U	Transglycosylase-associated protein
HZZ00_33710	ENOG4105D0M	Protease HtpX homolog
HZZ00_33715	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HZZ00_33720	ENOG4105C8S	subunit m
HZZ00_33725	ENOG4105D65	subunit l
HZZ00_33730	ENOG41082X4	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HZZ00_33735	ENOG4107YX3	NADH dehydrogenase subunit j
HZZ00_33740	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HZZ00_33745	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HZZ00_33750	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HZZ00_33755	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HZZ00_33760	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HZZ00_33780	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
HZZ00_33785	ENOG4105DQU	oxidoreductase, subunit beta
HZZ00_33810	ENOG4108FKH	Transglycosylase SLT domain
HZZ00_33815	ENOG410667J	hydrolase
HZZ00_33830	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HZZ00_33835	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HZZ00_33840	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HZZ00_33855	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HZZ00_33865	ENOG4105D65	subunit l
HZZ00_33870	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HZZ00_33875	ENOG41087XN	oxidoreductase
HZZ00_33880	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HZZ00_33885	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HZZ00_33890	ENOG4108IEH	NADH dehydrogenase subunit g
HZZ00_33895	ENOG4107QIZ	NADH dehydrogenase
HZZ00_33905	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HZZ00_33910	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HZZ00_33915	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HZZ00_33930	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HZZ00_33940	ENOG4105KNA	-acetyltransferase
HZZ00_33950	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HZZ00_33960	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
HZZ00_33975	ENOG4105EV6	Pfam:DUF178
HZZ00_33980	ENOG4105VEQ	Cold shock protein
HZZ00_33985	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HZZ00_33995	ENOG4105F0K	SARP family transcriptional regulator
HZZ00_34040	ENOG4108R86	Transcriptional regulator
HZZ00_34055	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
HZZ00_34060	ENOG4105DVY	radical SAM domain protein
HZZ00_34070	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HZZ00_34075	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HZZ00_34080	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HZZ00_34125	ENOG4105CRE	cytochrome C
HZZ00_34130	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
HZZ00_34135	ENOG4107QIV	Cytochrome c biogenesis protein
HZZ00_34150	ENOG4108RH7	phosphoglycerate mutase
HZZ00_34155	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HZZ00_34175	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HZZ00_34195	ENOG4108ME1	Peptidase M55 D-aminopeptidase
HZZ00_34205	ENOG4105CRK	lysyL-tRNA synthetase
HZZ00_34210	ENOG41062D9	Histidine kinase
HZZ00_34220	ENOG4108UZX	fmn reductase
HZZ00_34225	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
HZZ00_34230	ENOG4105KK4	UPF0060 membrane protein
HZZ00_34255	ENOG4105E0Y	RtcB Protein
HZZ00_34275	ENOG4105DK7	lysyl-tRNA synthetase
HZZ00_34280	ENOG4105C75	arginyL-tRNA synthetase
HZZ00_34295	ENOG4107T94	Endo-14-beta-xylanase
HZZ00_34320	ENOG4108RYK	Nad-dependent epimerase dehydratase
HZZ00_34325	ENOG4108M8W	Monooxygenase
HZZ00_34330	ENOG4105D52	delta-aminolevulinic acid dehydratase
HZZ00_34370	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HZZ00_34375	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HZZ00_34380	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HZZ00_34385	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
HZZ00_34435	ENOG4105DGU	Histone deacetylase
HZZ00_34440	ENOG4106UW1	Major Facilitator superfamily
HZZ00_34470	ENOG4105II7	pyrroline-5-carboxylate reductase
HZZ00_34485	ENOG4106H77	Inherit from COG: SH3 type 3 domain-containing protein
HZZ00_34490	ENOG4108762	serine threonine protein kinase
HZZ00_34495	ENOG4105C01	Dihydroxy-acid dehydratase
HZZ00_34505	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
HZZ00_34510	ENOG4107R33	ppx gppa phosphatase
HZZ00_34515	ENOG4108JWX	
HZZ00_34530	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
HZZ00_34540	ENOG4105CEN	a g-specific adenine glycosylase
HZZ00_34545	ENOG4105NAF	rna polymerase sigma factor
HZZ00_34550	ENOG41075QH	Lipoprotein CseA
HZZ00_34555	ENOG4108PYU	two-component system response regulator
HZZ00_34560	ENOG4108FKE	two-component system sensor kinase
HZZ00_34580	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HZZ00_34585	ENOG4108IG5	Transcriptional regulator
HZZ00_34590	ENOG4105DR5	peptidase
HZZ00_34640	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HZZ00_34650	ENOG4108IYU	L-aspartate oxidase
HZZ00_34655	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HZZ00_34665	ENOG4105C5W	Aldolase
HZZ00_34680	ENOG4105WH1	Two component transcriptional regulator luxr family
HZZ00_34695	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HZZ00_34710	ENOG4105CRK	lysyL-tRNA synthetase
HZZ00_34730	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HZZ00_34740	ENOG4105EUJ	GTP cyclohydrolase i
HZZ00_34750	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HZZ00_34755	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HZZ00_34770	ENOG4105F0N	pyrophosphate phospho-hydrolase
HZZ00_34785	ENOG41082VC	UPF0145 protein
HZZ00_34790	ENOG4107TXC	Transcriptional regulator
HZZ00_34795	ENOG4105CVK	Glutamate decarboxylase
HZZ00_34805	ENOG4105C26	Dehydrogenase
HZZ00_34845	ENOG4105C2M	dna polymerase I
HZZ00_34860	ENOG4105EE0	oxidoreductase
HZZ00_34865	ENOG41065HY	1,4-beta-cellobiosidase
HZZ00_34895	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
HZZ00_34905	ENOG4105CVJ	phosphoglycerate mutase
HZZ00_34910	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HZZ00_35025	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HZZ00_35045	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HZZ00_35050	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HZZ00_35070	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HZZ00_35075	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
HZZ00_35080	ENOG4105WN5	stage II sporulation protein
HZZ00_35085	ENOG4108I5C	dEAD DEAH box helicase
HZZ00_35145	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HZZ00_35160	ENOG4105D74	hydrolase
HZZ00_35175	ENOG4105P8F	nudix hydrolase
HZZ00_35195	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HZZ00_35295	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HZZ00_35310	ENOG4105XTG	Pfam:DUF156
HZZ00_35345	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
HZZ00_35370	ENOG4107RSM	transcriptional regulator
HZZ00_35380	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HZZ00_35390	ENOG4105JSC	dimethylmenaquinone methyltransferase
HZZ00_35400	ENOG4105YIP	Tetr family transcriptional regulator
HZZ00_35415	ENOG4105DRR	Transcriptional regulator, GntR family
HZZ00_35420	ENOG4105HHS	UPF0256 protein
HZZ00_35430	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HZZ00_35435	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HZZ00_35440	ENOG41090R7	Ferric uptake
HZZ00_35445	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
HZZ00_35465	ENOG4105PKJ	carbohydrate binding
HZZ00_35470	ENOG4105KHC	sulfurtransferase
HZZ00_35535	ENOG4107NHD	transcriptional regulator
HZZ00_35540	ENOG4105ETE	Transcriptional regulator (LacI family
HZZ00_35545	ENOG4105C0H	protease
HZZ00_35555	ENOG4105ETX	regulatoR
HZZ00_35565	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
HZZ00_35570	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
HZZ00_35575	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HZZ00_35585	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HZZ00_35615	ENOG4105VPX	protein, conserved in bacteria
HZZ00_35625	ENOG4105CJ3	phosphate transporter
HZZ00_35630	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HZZ00_35650	ENOG4105DNP	FAD linked oxidase domain protein
HZZ00_35655	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
HZZ00_35660	ENOG4107SN7	NLP P60 protein
HZZ00_35685	ENOG4105CHR	reductase
HZZ00_35690	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HZZ00_35775	ENOG4108Q50	Histidine kinase
HZZ00_35810	ENOG4105D5U	fad dependent oxidoreductase
HZZ00_35815	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HZZ00_35840	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HZZ00_35875	ENOG4105C1J	atp-dependent rna helicase
HZZ00_35920	ENOG4105CQ7	ATP-dependent helicase
HZZ00_35935	ENOG4108TAC	
HZZ00_35950	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HZZ00_35970	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
HZZ00_35975	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
HZZ00_35980	ENOG410839H	phosphoribosylformylglycinamidine synthase
HZZ00_36005	ENOG4105C8V	SAICAR synthetase
HZZ00_36020	ENOG4105C12	Phosphoribosylglycinamide synthetase
HZZ00_36060	ENOG4107ZQV	short-chain dehydrogenase reductase
HZZ00_36100	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HZZ00_36115	ENOG4108Z6B	deaminase
HZZ00_36130	ENOG4106C0N	stress responsive alpha-beta barrel domain-containing protein
HZZ00_36135	ENOG4108N6D	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HZZ00_36140	ENOG4108N6D	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HZZ00_36150	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
HZZ00_36170	ENOG410905P	Pyridoxamine 5-phosphate
HZZ00_36180	ENOG4105EDW	glycosyl transferase, family 39
HZZ00_36190	ENOG4105BZU	Histidine kinase
HZZ00_36195	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HZZ00_36235	ENOG4105CEY	Amp-dependent synthetase and ligase
HZZ00_36240	ENOG4105NAF	rna polymerase sigma factor
HZZ00_36310	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HZZ00_36330	ENOG4107T6F	Xaa-Pro aminopeptidase
HZZ00_36370	ENOG4105DBE	peroxidase
HZZ00_36380	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HZZ00_36385	ENOG410667J	hydrolase
HZZ00_36410	ENOG4105DA5	(ABC) transporter
HZZ00_36425	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
HZZ00_36435	ENOG4108K4B	hydrolase
HZZ00_36440	ENOG4108JJ9	ABC, transporter
HZZ00_36445	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HZZ00_36450	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HZZ00_36455	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HZZ00_36460	ENOG4107P2S	Transcriptional regulator
HZZ00_36475	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HZZ00_36500	ENOG4106048	Cupin 2, conserved barrel domain protein
HZZ00_36505	ENOG41082T9	Membrane
HZZ00_36510	ENOG4105KJF	protein tyrosine phosphatase
HZZ00_36515	ENOG4105C28	cystathionine
HZZ00_36540	ENOG4105F27	Major Facilitator
HZZ00_36565	ENOG4105CDU	Replicative dna helicase
HZZ00_36575	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HZZ00_36580	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HZZ00_36585	ENOG4107YH6	single-stranded DNA-binding protein
HZZ00_36590	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
HZZ00_36615	ENOG4105BZ4	penicillin-binding protein
HZZ00_36635	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HZZ00_36660	ENOG4105CH2	amidohydrolase
HZZ00_36685	ENOG4107U9B	transcriptional regulator
HZZ00_36690	ENOG4105F2Z	3-oxoadipate enol-lactonase
HZZ00_36700	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HZZ00_36710	ENOG4105C9M	aspartyl-trna synthetase
HZZ00_36725	ENOG4105EUB	pirin domain protein
HZZ00_36735	ENOG4105CSU	acyl-Coa dehydrogenase
HZZ00_36740	ENOG4105DFM	M18 family aminopeptidase
HZZ00_36775	ENOG4105DJB	Major Facilitator Superfamily
HZZ00_36845	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
HZZ00_36850	ENOG4105CPP	Dehydrogenase, E1 component
HZZ00_36870	ENOG4107QPV	Serine Threonine protein kinase
HZZ00_36890	ENOG4107SVH	Potassium channel protein
HZZ00_36905	ENOG4107QSN	dihydrolipoamide acetyltransferase
HZZ00_36925	ENOG4108IG5	Transcriptional regulator
HZZ00_36930	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HZZ00_36955	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
HZZ00_36960	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
HZZ00_36965	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
HZZ00_36970	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
HZZ00_36975	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HZZ00_37010	ENOG4105TV9	FHA Domain-Containing protein
HZZ00_37015	ENOG4105HZM	Fha domain containing protein
HZZ00_37040	ENOG4108RN7	integral membrane protein
HZZ00_37045	ENOG4108U4N	(sortase) family
HZZ00_37065	ENOG4105ZJT	Cell division protein CrgA
HZZ00_37110	ENOG4108UGD	Serine Threonine protein kinase
HZZ00_37140	ENOG4108HMN	Caspase domain
HZZ00_37170	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HZZ00_37175	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HZZ00_37180	ENOG4105K7N	UPF0232 protein
HZZ00_37185	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HZZ00_37190	ENOG4108J5G	6-phosphogluconate dehydrogenase
HZZ00_37195	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HZZ00_37750	ENOG4105K7N	UPF0232 protein
HZZ00_37845	ENOG4107YH6	single-stranded DNA-binding protein
HZZ00_38000	ENOG4105CDU	Replicative dna helicase
HZZ00_38060	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)