locus-tag	class	description
FNV58_00155	COG1475	DNA binding
FNV58_00170	COG1278	Cold shock
FNV58_00215	COG4974	Belongs to the 'phage' integrase family
FNV58_00260	COG1131	(ABC) transporter
FNV58_00410	COG2188	Transcriptional regulator
FNV58_00430	COG0546	phosphoglycolate phosphatase activity
FNV58_00455	COG0305	Participates in initiation and elongation during chromosome replication
FNV58_00480	COG1857	crispr-associated protein
FNV58_00635	COG4195	phage-related replication protein
FNV58_00690	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNV58_00690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNV58_00750	COG0587	DNA-directed DNA polymerase activity
FNV58_00765	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FNV58_01270	COG0717	Belongs to the dCTP deaminase family
FNV58_01420	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FNV58_01505	COG1278	Cold shock
FNV58_01590	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FNV58_01605	COG2197	response regulator
FNV58_01650	COG0596	Alpha beta hydrolase
FNV58_01705	COG0596	Alpha beta hydrolase
FNV58_01765	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FNV58_01975	COG1959	2 iron, 2 sulfur cluster binding
FNV58_02020	COG0477	Major facilitator Superfamily
FNV58_02130	COG2124	cytochrome p450
FNV58_02200	COG1733	regulation of RNA biosynthetic process
FNV58_02205	COG0604	alcohol dehydrogenase
FNV58_02220	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV58_02320	COG0659	secondary active sulfate transmembrane transporter activity
FNV58_02330	COG2824	Alkylphosphonate utilization operon protein PhnA
FNV58_02370	COG1136	(ABC) transporter
FNV58_02410	COG0456	acetyltransferase
FNV58_02490	COG2267	carboxylic ester hydrolase activity
FNV58_02495	COG2197	response regulator
FNV58_02545	COG2130	NADP-dependent
FNV58_02615	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_02635	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FNV58_02665	COG0671	phosphoesterase, PA-phosphatase related
FNV58_02680	COG2814	Major facilitator Superfamily
FNV58_02700	COG0726	polysaccharide deacetylase
FNV58_02720	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV58_02725	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV58_02765	COG2267	carboxylic ester hydrolase activity
FNV58_02830	COG4585	Histidine kinase
FNV58_02835	COG2197	response regulator
FNV58_02855	COG1278	Cold shock
FNV58_02870	COG0596	Alpha beta hydrolase
FNV58_02875	COG2045	Belongs to the ComB family
FNV58_02915	COG3293	Transposase
FNV58_03065	COG3629	intracellular signal transduction
FNV58_03065	COG3903	Transcriptional regulator
FNV58_03085	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNV58_03110	COG0583	DNA-binding transcription factor activity
FNV58_03120	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNV58_03150	COG0640	Transcriptional regulator
FNV58_03180	COG1609	Transcriptional regulator
FNV58_03200	COG3250	beta-galactosidase activity
FNV58_03205	COG3250	beta-galactosidase activity
FNV58_03220	COG3507	Belongs to the glycosyl hydrolase 43 family
FNV58_03230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV58_03240	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_03305	COG3290	protein histidine kinase activity
FNV58_03330	COG1131	(ABC) transporter
FNV58_03340	COG1595	DNA-templated transcription, initiation
FNV58_03425	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FNV58_03435	COG1309	transcriptional regulator
FNV58_03510	COG0745	RESPONSE REGULATOR receiver
FNV58_03515	COG2205	protein histidine kinase activity
FNV58_03545	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FNV58_03570	COG4585	Histidine kinase
FNV58_03575	COG2197	response regulator
FNV58_03580	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_03585	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV58_03585	COG0567	Dehydrogenase, E1 component
FNV58_03605	COG1090	epimerase
FNV58_03610	COG1595	DNA-templated transcription, initiation
FNV58_03630	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV58_03640	COG1960	acyl-CoA dehydrogenase activity
FNV58_03670	COG0778	Nitroreductase
FNV58_03675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV58_03680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV58_03710	COG1063	alcohol dehydrogenase
FNV58_03715	COG2124	cytochrome p450
FNV58_03715	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FNV58_03755	COG1309	transcriptional regulator
FNV58_03770	COG1660	Displays ATPase and GTPase activities
FNV58_03785	COG0596	Alpha beta hydrolase
FNV58_03970	COG2890	protein-(glutamine-N5) methyltransferase activity
FNV58_03990	COG0069	glutamate synthase activity
FNV58_03995	COG0028	Belongs to the TPP enzyme family
FNV58_04000	COG0596	Alpha beta hydrolase
FNV58_04010	COG1366	Belongs to the anti-sigma-factor antagonist family
FNV58_04020	COG1024	Enoyl-CoA hydratase
FNV58_04055	COG1120	ATPase activity
FNV58_04060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNV58_04070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV58_04075	COG1535	isochorismatase
FNV58_04075	COG3433	isochorismatase activity
FNV58_04095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV58_04150	COG2226	methyltransferase
FNV58_04190	COG1522	sequence-specific DNA binding
FNV58_04205	COG0667	Aldo Keto reductase
FNV58_04245	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_04260	COG3537	Alpha-1,2-mannosidase
FNV58_04265	COG0667	Aldo Keto reductase
FNV58_04270	COG1309	transcriptional regulator
FNV58_04275	COG3619	membrane
FNV58_04280	COG0583	DNA-binding transcription factor activity
FNV58_04285	COG3876	Protein conserved in bacteria
FNV58_04305	COG0395	ABC-type sugar transport system, permease component
FNV58_04320	COG1902	pentaerythritol trinitrate reductase activity
FNV58_04340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV58_04355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV58_04365	COG1073	alpha beta
FNV58_04370	COG1024	Enoyl-CoA hydratase
FNV58_04380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNV58_04405	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_04425	COG1309	transcriptional regulator
FNV58_04430	COG0655	NAD(P)H dehydrogenase (quinone) activity
FNV58_04440	COG1733	regulation of RNA biosynthetic process
FNV58_04455	COG1309	transcriptional regulator
FNV58_04475	COG1960	acyl-CoA dehydrogenase activity
FNV58_04480	COG1960	acyl-CoA dehydrogenase activity
FNV58_04490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV58_04495	COG1733	regulation of RNA biosynthetic process
FNV58_04500	COG1960	acyl-CoA dehydrogenase activity
FNV58_04510	COG1024	Enoyl-CoA hydratase
FNV58_04515	COG0318	PFAM AMP-dependent synthetase and ligase
FNV58_04520	COG1309	transcriptional regulator
FNV58_04525	COG0667	Aldo Keto reductase
FNV58_04530	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FNV58_04555	COG0800	Aldolase
FNV58_04565	COG4948	Mandelate Racemase Muconate Lactonizing
FNV58_04585	COG0395	ABC-type sugar transport system, permease component
FNV58_04590	COG1175	transmembrane transport
FNV58_04600	COG3345	alpha-galactosidase
FNV58_04605	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNV58_04635	COG1309	transcriptional regulator
FNV58_04665	COG0366	Alpha amylase catalytic
FNV58_04675	COG2207	Transcriptional regulator
FNV58_04680	COG2223	nitrite transmembrane transporter activity
FNV58_04710	COG1012	belongs to the aldehyde dehydrogenase family
FNV58_04740	COG1609	Transcriptional regulator
FNV58_04810	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FNV58_04830	COG0488	(ABC) transporter
FNV58_04835	COG0488	(ABC) transporter
FNV58_04890	COG1764	response to oxidative stress
FNV58_04930	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNV58_04960	COG0477	Major facilitator Superfamily
FNV58_05000	COG3345	alpha-galactosidase
FNV58_05020	COG2186	Transcriptional regulator
FNV58_05030	COG1175	transmembrane transport
FNV58_05035	COG0395	ABC-type sugar transport system, permease component
FNV58_05050	COG3618	amidohydrolase
FNV58_05055	COG1063	alcohol dehydrogenase
FNV58_05060	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_05065	COG0800	Aldolase
FNV58_05080	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNV58_05090	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_05100	COG0247	lactate metabolic process
FNV58_05110	COG3693	PFAM glycoside hydrolase, family 10
FNV58_05140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV58_05150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV58_05155	COG0800	Aldolase
FNV58_05160	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_05165	COG1063	alcohol dehydrogenase
FNV58_05175	COG3618	amidohydrolase
FNV58_05180	COG4948	Mandelate Racemase Muconate Lactonizing
FNV58_05185	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNV58_05190	COG1129	ABC transporter
FNV58_05205	COG2755	lipolytic protein G-D-S-L family
FNV58_05220	COG3507	Belongs to the glycosyl hydrolase 43 family
FNV58_05240	COG0395	ABC-type sugar transport system, permease component
FNV58_05245	COG4209	transmembrane transport
FNV58_05270	COG1501	Belongs to the glycosyl hydrolase 31 family
FNV58_05305	COG0519	Catalyzes the synthesis of GMP from XMP
FNV58_05305	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FNV58_05320	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV58_05335	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_05340	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_05345	COG2188	Transcriptional regulator
FNV58_05430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNV58_05440	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FNV58_05480	COG3469	chitinase activity
FNV58_05495	COG3629	intracellular signal transduction
FNV58_05495	COG3903	Transcriptional regulator
FNV58_05535	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_05540	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_05550	COG1764	response to oxidative stress
FNV58_05615	COG2208	phosphoserine phosphatase activity
FNV58_05615	COG2770	Histidine kinase
FNV58_05635	COG0583	DNA-binding transcription factor activity
FNV58_05650	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_05675	COG0702	epimerase
FNV58_05685	COG2271	Major facilitator Superfamily
FNV58_05690	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNV58_05690	COG2755	lipolytic protein G-D-S-L family
FNV58_05730	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FNV58_05775	COG2197	response regulator
FNV58_05790	COG1082	Xylose isomerase domain protein TIM barrel
FNV58_05800	COG1082	Xylose isomerase domain protein TIM barrel
FNV58_05820	COG2226	methyltransferase
FNV58_05825	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FNV58_05855	COG4213	ABC transporter substrate-binding protein
FNV58_05865	COG4213	ABC transporter substrate-binding protein
FNV58_05875	COG4214	carbohydrate transport
FNV58_05885	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNV58_05890	COG1414	Transcriptional regulator
FNV58_05915	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNV58_05920	COG0640	Transcriptional regulator
FNV58_05930	COG0248	Ppx GppA phosphatase
FNV58_05975	COG0477	Major facilitator Superfamily
FNV58_05985	COG2124	cytochrome p450
FNV58_06060	COG1191	sigma factor activity
FNV58_06065	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FNV58_06150	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FNV58_06160	COG1064	alcohol dehydrogenase
FNV58_06190	COG0009	L-threonylcarbamoyladenylate synthase
FNV58_06200	COG0443	Heat shock 70 kDa protein
FNV58_06205	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FNV58_06220	COG0542	response to heat
FNV58_06235	COG1414	Transcriptional regulator
FNV58_06240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV58_06245	COG2610	gluconate transmembrane transporter activity
FNV58_06250	COG4948	Mandelate Racemase Muconate Lactonizing
FNV58_06265	COG1136	(ABC) transporter
FNV58_06270	COG4585	Histidine kinase
FNV58_06275	COG2197	response regulator
FNV58_06280	COG1309	transcriptional regulator
FNV58_06285	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_06295	COG1595	DNA-templated transcription, initiation
FNV58_06305	COG2362	D-Aminopeptidase
FNV58_06335	COG2814	Major facilitator Superfamily
FNV58_06350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FNV58_06355	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV58_06360	COG2186	Transcriptional regulator
FNV58_06380	COG5006	permease, DMT superfamily
FNV58_06395	COG0477	Major facilitator Superfamily
FNV58_06450	COG0464	growth
FNV58_06555	COG1940	carbohydrate kinase activity
FNV58_06555	COG1846	Transcriptional regulator
FNV58_06635	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNV58_06655	COG4585	Histidine kinase
FNV58_06660	COG2197	response regulator
FNV58_06705	COG1881	PFAM PEBP family protein
FNV58_06720	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_06725	COG2186	Transcriptional regulator
FNV58_06730	COG1024	Enoyl-CoA hydratase
FNV58_06735	COG1960	acyl-CoA dehydrogenase activity
FNV58_06740	COG1960	acyl-CoA dehydrogenase activity
FNV58_06745	COG0318	PFAM AMP-dependent synthetase and ligase
FNV58_06755	COG1024	Enoyl-CoA hydratase
FNV58_06760	COG0183	Belongs to the thiolase family
FNV58_06765	COG1960	acyl-CoA dehydrogenase activity
FNV58_06770	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_06785	COG1024	Enoyl-CoA hydratase
FNV58_06790	COG1024	Enoyl-CoA hydratase
FNV58_06810	COG0410	ABC transporter
FNV58_06840	COG1960	acyl-CoA dehydrogenase activity
FNV58_06850	COG1960	acyl-CoA dehydrogenase activity
FNV58_06855	COG2272	Belongs to the type-B carboxylesterase lipase family
FNV58_06860	COG1024	Enoyl-CoA hydratase
FNV58_06875	COG0183	Belongs to the thiolase family
FNV58_06880	COG0318	PFAM AMP-dependent synthetase and ligase
FNV58_06900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV58_06915	COG0318	PFAM AMP-dependent synthetase and ligase
FNV58_06925	COG0318	PFAM AMP-dependent synthetase and ligase
FNV58_06935	COG1024	Enoyl-CoA hydratase
FNV58_06945	COG1309	transcriptional regulator
FNV58_06985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV58_06990	COG1012	belongs to the aldehyde dehydrogenase family
FNV58_07005	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_07015	COG4638	Rieske (2fe-2S)
FNV58_07025	COG1228	amidohydrolase
FNV58_07035	COG1960	acyl-CoA dehydrogenase activity
FNV58_07055	COG1960	acyl-CoA dehydrogenase activity
FNV58_07095	COG1846	Transcriptional regulator
FNV58_07100	COG1309	transcriptional regulator
FNV58_07105	COG4585	Histidine kinase
FNV58_07110	COG2197	response regulator
FNV58_07130	COG2814	Major facilitator Superfamily
FNV58_07180	COG0277	FAD linked oxidase domain protein
FNV58_07195	COG0366	Alpha amylase catalytic
FNV58_07205	COG3281	Trehalose synthase
FNV58_07210	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FNV58_07240	COG0577	efflux transmembrane transporter activity
FNV58_07240	COG1136	(ABC) transporter
FNV58_07340	COG0477	Major facilitator Superfamily
FNV58_07365	COG0494	nUDIX hydrolase
FNV58_07395	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FNV58_07450	COG3883	PFAM NLP P60 protein
FNV58_07450	COG0791	NLP P60 protein
FNV58_07495	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FNV58_07570	COG0539	negative regulation of cytoplasmic translation
FNV58_07585	COG4974	Belongs to the 'phage' integrase family
FNV58_07630	COG0531	amino acid
FNV58_07640	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNV58_07660	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FNV58_07730	COG3189	MarR family transcriptional regulator
FNV58_07795	COG0396	ATPase activity
FNV58_07850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV58_07850	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_07850	COG3321	synthase
FNV58_07850	COG4221	oxidoreductase activity
FNV58_07970	COG3903	Transcriptional regulator
FNV58_07970	COG3629	intracellular signal transduction
FNV58_08035	COG3316	Transposase and inactivated derivatives
FNV58_08055	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FNV58_08055	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FNV58_08270	COG2226	methyltransferase
FNV58_08410	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV58_08415	COG1793	dna ligase
FNV58_08450	COG2826	transposase and inactivated derivatives, IS30 family
FNV58_08460	COG3903	Transcriptional regulator
FNV58_08460	COG3629	intracellular signal transduction
FNV58_08530	COG1278	Cold shock
FNV58_08580	COG1484	DNA-dependent DNA replication
FNV58_08585	COG4584	PFAM Integrase catalytic
FNV58_08645	COG3345	alpha-galactosidase
FNV58_08655	COG1175	transmembrane transport
FNV58_08665	COG1846	Transcriptional regulator
FNV58_08665	COG1940	carbohydrate kinase activity
FNV58_08680	COG0574	Belongs to the PEP-utilizing enzyme family
FNV58_08680	COG3848	Pyruvate phosphate dikinase
FNV58_08740	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV58_08745	COG1793	dna ligase
FNV58_08755	COG0539	negative regulation of cytoplasmic translation
FNV58_08780	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_08805	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FNV58_08850	COG2267	carboxylic ester hydrolase activity
FNV58_08945	COG2226	methyltransferase
FNV58_09120	COG3547	Transposase (IS116 IS110 IS902 family)
FNV58_09295	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FNV58_09325	COG1793	dna ligase
FNV58_09335	COG2826	transposase and inactivated derivatives, IS30 family
FNV58_09410	COG2801	Transposase and inactivated derivatives
FNV58_09460	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FNV58_09520	COG3387	PFAM Glycoside hydrolase 15-related
FNV58_09565	COG2409	Drug exporters of the RND superfamily
FNV58_09570	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV58_09580	COG2197	response regulator
FNV58_09595	COG1943	Transposase
FNV58_09620	COG3655	Transcriptional regulator
FNV58_09685	COG1335	isochorismatase
FNV58_09695	COG3328	transposase activity
FNV58_09770	COG0831	urea catabolic process
FNV58_09770	COG0832	Belongs to the urease beta subunit family
FNV58_09775	COG0804	urea catabolic process
FNV58_09780	COG0830	nickel cation binding
FNV58_09785	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FNV58_09790	COG0829	nickel cation binding
FNV58_09800	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FNV58_09820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNV58_09870	COG1215	transferase activity, transferring glycosyl groups
FNV58_09885	COG0438	transferase activity, transferring glycosyl groups
FNV58_09895	COG4221	oxidoreductase activity
FNV58_09915	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FNV58_09965	COG1618	nucleotide phosphatase activity, acting on free nucleotides
FNV58_10060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV58_10100	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FNV58_10150	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FNV58_10255	COG2304	oxidoreductase activity
FNV58_10290	COG0328	RNA-DNA hybrid ribonuclease activity
FNV58_10350	COG0601	transmembrane transport
FNV58_10355	COG0747	negative chemotaxis
FNV58_10385	COG3835	regulator
FNV58_10390	COG2010	Cytochrome c
FNV58_10390	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNV58_10395	COG2080	2 iron, 2 sulfur cluster binding
FNV58_10420	COG0009	L-threonylcarbamoyladenylate synthase
FNV58_10510	COG0596	Alpha beta hydrolase
FNV58_10515	COG0740	serine-type endopeptidase activity
FNV58_10520	COG0740	serine-type endopeptidase activity
FNV58_10530	COG2318	DinB family
FNV58_10545	COG0784	Response regulator, receiver
FNV58_10550	COG4251	negative regulation of phosphorylation
FNV58_10610	COG0842	Transport permease protein
FNV58_10610	COG1131	(ABC) transporter
FNV58_10610	COG1716	ATPase activity
FNV58_10630	COG2207	Transcriptional regulator
FNV58_10640	COG0667	Aldo Keto reductase
FNV58_10645	COG0583	DNA-binding transcription factor activity
FNV58_10660	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV58_10665	COG0346	lactoylglutathione lyase activity
FNV58_10670	COG0671	phosphoesterase, PA-phosphatase related
FNV58_10680	COG0412	Dienelactone hydrolase
FNV58_10685	COG0667	Aldo Keto reductase
FNV58_10695	COG1012	belongs to the aldehyde dehydrogenase family
FNV58_10700	COG4941	Belongs to the sigma-70 factor family
FNV58_10715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV58_10725	COG0431	NADPH-dependent FMN reductase
FNV58_10745	COG0702	epimerase
FNV58_10830	COG0531	amino acid
FNV58_10835	COG1940	carbohydrate kinase activity
FNV58_10840	COG3250	beta-galactosidase activity
FNV58_10860	COG3345	alpha-galactosidase
FNV58_10865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV58_10885	COG0667	Aldo Keto reductase
FNV58_10915	COG0367	asparagine synthase
FNV58_10920	COG0069	glutamate synthase activity
FNV58_10925	COG2235	arginine
FNV58_10940	COG0673	inositol 2-dehydrogenase activity
FNV58_10945	COG3511	phospholipase C
FNV58_10980	COG1404	Belongs to the peptidase S8 family
FNV58_10995	COG1672	PFAM Archaeal ATPase
FNV58_10995	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FNV58_11035	COG0318	PFAM AMP-dependent synthetase and ligase
FNV58_11040	COG2366	antibiotic biosynthetic process
FNV58_11050	COG2070	2-Nitropropane dioxygenase
FNV58_11060	COG0515	serine threonine protein kinase
FNV58_11070	COG1960	acyl-CoA dehydrogenase activity
FNV58_11095	COG4172	Belongs to the ABC transporter superfamily
FNV58_11100	COG4171	peptide transport system, permease
FNV58_11110	COG0747	negative chemotaxis
FNV58_11125	COG0019	diaminopimelate decarboxylase activity
FNV58_11130	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNV58_11135	COG0534	Mate efflux family protein
FNV58_11140	COG1609	Transcriptional regulator
FNV58_11145	COG0673	inositol 2-dehydrogenase activity
FNV58_11165	COG3962	Belongs to the TPP enzyme family
FNV58_11170	COG3718	enzyme involved in inositol metabolism
FNV58_11180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV58_11210	COG0028	Belongs to the TPP enzyme family
FNV58_11215	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_11220	COG2072	flavoprotein involved in K transport
FNV58_11225	COG4638	Rieske (2fe-2S)
FNV58_11230	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_11235	COG3386	PFAM SMP-30 Gluconolaconase
FNV58_11240	COG1960	acyl-CoA dehydrogenase activity
FNV58_11245	COG1960	acyl-CoA dehydrogenase activity
FNV58_11255	COG1960	acyl-CoA dehydrogenase activity
FNV58_11260	COG0604	alcohol dehydrogenase
FNV58_11270	COG0318	PFAM AMP-dependent synthetase and ligase
FNV58_11275	COG0427	acetyl-CoA hydrolase
FNV58_11305	COG2186	Transcriptional regulator
FNV58_11310	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_11320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV58_11325	COG1960	acyl-CoA dehydrogenase activity
FNV58_11385	COG1309	transcriptional regulator
FNV58_11395	COG1335	isochorismatase
FNV58_11405	COG1733	regulation of RNA biosynthetic process
FNV58_11470	COG2072	flavoprotein involved in K transport
FNV58_11495	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FNV58_11500	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FNV58_11505	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FNV58_11515	COG0531	amino acid
FNV58_11565	COG0604	alcohol dehydrogenase
FNV58_11565	COG3321	synthase
FNV58_11575	COG1073	alpha beta
FNV58_11620	COG0363	glucosamine-6-phosphate deaminase activity
FNV58_11625	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FNV58_11645	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FNV58_11650	COG2376	Dihydroxyacetone kinase
FNV58_11655	COG1461	Dihydroxyacetone kinase
FNV58_11670	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_11700	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNV58_11700	COG1902	pentaerythritol trinitrate reductase activity
FNV58_11705	COG2890	protein-(glutamine-N5) methyltransferase activity
FNV58_11725	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FNV58_11750	COG3458	cephalosporin-C deacetylase activity
FNV58_11765	COG2188	Transcriptional regulator
FNV58_11775	COG2226	methyltransferase
FNV58_11780	COG0366	Alpha amylase catalytic
FNV58_11785	COG2267	carboxylic ester hydrolase activity
FNV58_11795	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_11840	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNV58_11855	COG4941	Belongs to the sigma-70 factor family
FNV58_11865	COG3795	YCII-related domain
FNV58_11875	COG0346	lactoylglutathione lyase activity
FNV58_11880	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_11890	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FNV58_11895	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FNV58_11900	COG1686	Belongs to the peptidase S11 family
FNV58_11905	COG5650	phosphatidylinositol metabolic process
FNV58_11915	COG2066	Belongs to the glutaminase family
FNV58_11930	COG1113	amino acid transport
FNV58_11940	COG1968	undecaprenyl-diphosphatase activity
FNV58_11945	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FNV58_11950	COG1993	acr, cog1993
FNV58_11955	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FNV58_11980	COG1175	transmembrane transport
FNV58_12010	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FNV58_12025	COG1960	acyl-CoA dehydrogenase activity
FNV58_12035	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNV58_12075	COG1215	transferase activity, transferring glycosyl groups
FNV58_12090	COG0633	Ferredoxin
FNV58_12090	COG3217	Mosc domain protein beta barrel domain protein
FNV58_12110	COG1349	DNA-binding transcription factor activity
FNV58_12135	COG0577	efflux transmembrane transporter activity
FNV58_12140	COG1136	(ABC) transporter
FNV58_12165	COG1940	carbohydrate kinase activity
FNV58_12170	COG3145	DNA-N1-methyladenine dioxygenase activity
FNV58_12175	COG2813	Specifically methylates the guanine in position
FNV58_12200	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNV58_12205	COG1349	DNA-binding transcription factor activity
FNV58_12210	COG3537	Alpha-1,2-mannosidase
FNV58_12220	COG1174	glycine betaine transport
FNV58_12240	COG2018	Roadblock/LC7 domain
FNV58_12270	COG3320	Male sterility
FNV58_12270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV58_12280	COG0318	PFAM AMP-dependent synthetase and ligase
FNV58_12290	COG0596	Alpha beta hydrolase
FNV58_12295	COG4565	transcriptional regulatory protein
FNV58_12300	COG3290	protein histidine kinase activity
FNV58_12310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV58_12340	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_12345	COG1271	oxidase subunit
FNV58_12400	COG3387	PFAM Glycoside hydrolase 15-related
FNV58_12420	COG2223	nitrite transmembrane transporter activity
FNV58_12445	COG2197	response regulator
FNV58_12450	COG4585	Histidine kinase
FNV58_12465	COG0445	tRNA wobble uridine modification
FNV58_12470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNV58_12475	COG1660	Displays ATPase and GTPase activities
FNV58_12520	COG3345	alpha-galactosidase
FNV58_12550	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FNV58_12575	COG0204	Acyl-transferase
FNV58_12605	COG0584	glycerophosphoryl diester phosphodiesterase
FNV58_12665	COG1309	transcriptional regulator
FNV58_12690	COG0640	Transcriptional regulator
FNV58_12695	COG1902	pentaerythritol trinitrate reductase activity
FNV58_12710	COG2197	response regulator
FNV58_12715	COG4585	Histidine kinase
FNV58_12720	COG3963	phosphatidate phosphatase activity
FNV58_12745	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FNV58_12745	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FNV58_12785	COG0714	Associated with various cellular activities
FNV58_12790	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FNV58_12820	COG0596	Alpha beta hydrolase
FNV58_12825	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FNV58_12825	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FNV58_12830	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FNV58_12840	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FNV58_12855	COG2706	6-phosphogluconolactonase activity
FNV58_12860	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FNV58_12895	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNV58_12900	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FNV58_12905	COG2080	2 iron, 2 sulfur cluster binding
FNV58_12915	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FNV58_12930	COG2208	phosphoserine phosphatase activity
FNV58_12930	COG2770	Histidine kinase
FNV58_12950	COG0745	RESPONSE REGULATOR receiver
FNV58_12985	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_13045	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_13050	COG1733	regulation of RNA biosynthetic process
FNV58_13075	COG0667	Aldo Keto reductase
FNV58_13080	COG4221	oxidoreductase activity
FNV58_13100	COG0513	Belongs to the DEAD box helicase family
FNV58_13110	COG0432	Pfam Uncharacterised protein family UPF0047
FNV58_13115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV58_13120	COG1116	anion transmembrane transporter activity
FNV58_13130	COG2072	flavoprotein involved in K transport
FNV58_13140	COG1132	(ABC) transporter
FNV58_13150	COG1301	dicarboxylic acid transport
FNV58_13170	COG1132	(ABC) transporter
FNV58_13180	COG0254	rRNA binding
FNV58_13195	COG1946	Acyl-CoA thioesterase
FNV58_13205	COG2018	Roadblock/LC7 domain
FNV58_13270	COG3239	Fatty acid desaturase
FNV58_13275	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FNV58_13295	COG2115	Belongs to the xylose isomerase family
FNV58_13305	COG1940	carbohydrate kinase activity
FNV58_13305	COG1846	Transcriptional regulator
FNV58_13310	COG1113	amino acid transport
FNV58_13330	COG1012	belongs to the aldehyde dehydrogenase family
FNV58_13370	COG0515	serine threonine protein kinase
FNV58_13395	COG1960	acyl-CoA dehydrogenase activity
FNV58_13400	COG1960	acyl-CoA dehydrogenase activity
FNV58_13415	COG0492	ferredoxin-NADP+ reductase activity
FNV58_13420	COG1793	dna ligase
FNV58_13430	COG1012	belongs to the aldehyde dehydrogenase family
FNV58_13445	COG3424	synthase
FNV58_13450	COG2124	cytochrome p450
FNV58_13460	COG1960	acyl-CoA dehydrogenase activity
FNV58_13470	COG0242	peptide deformylase activity
FNV58_13480	COG3442	glutamine amidotransferase
FNV58_13485	COG0205	6-phosphofructokinase activity
FNV58_13500	COG2815	serine threonine protein kinase
FNV58_13500	COG0515	serine threonine protein kinase
FNV58_13505	COG3275	phosphorelay sensor kinase activity
FNV58_13510	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV58_13520	COG3279	Response regulator of the LytR AlgR family
FNV58_13530	COG1834	amidinotransferase
FNV58_13535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FNV58_13545	COG1510	regulation of RNA biosynthetic process
FNV58_13580	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FNV58_13605	COG0829	nickel cation binding
FNV58_13610	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FNV58_13620	COG0804	urea catabolic process
FNV58_13625	COG0832	Belongs to the urease beta subunit family
FNV58_13630	COG0831	urea catabolic process
FNV58_13640	COG0740	serine-type endopeptidase activity
FNV58_13680	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FNV58_13685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNV58_13690	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FNV58_13700	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FNV58_13705	COG2226	methyltransferase
FNV58_13735	COG0456	acetyltransferase
FNV58_13780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNV58_13790	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FNV58_13795	COG3663	DNA glycosylase
FNV58_13815	COG4585	Histidine kinase
FNV58_13820	COG2197	response regulator
FNV58_13825	COG1940	carbohydrate kinase activity
FNV58_13830	COG2188	Transcriptional regulator
FNV58_13835	COG1595	DNA-templated transcription, initiation
FNV58_13850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV58_13865	COG0626	cystathionine gamma-synthase activity
FNV58_13885	COG0583	DNA-binding transcription factor activity
FNV58_13895	COG1522	sequence-specific DNA binding
FNV58_13900	COG0419	ATPase involved in DNA repair
FNV58_13905	COG0420	3'-5' exonuclease activity
FNV58_13910	COG1739	Uncharacterized protein family UPF0029
FNV58_13930	COG2197	response regulator
FNV58_13940	COG1960	acyl-CoA dehydrogenase activity
FNV58_13955	COG1832	CoA-binding protein
FNV58_13965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNV58_13970	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FNV58_13995	COG2326	polyphosphate kinase activity
FNV58_14025	COG0110	maltose O-acetyltransferase activity
FNV58_14060	COG1609	Transcriptional regulator
FNV58_14100	COG0076	glutamate decarboxylase activity
FNV58_14125	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FNV58_14140	COG0183	Belongs to the thiolase family
FNV58_14145	COG1733	regulation of RNA biosynthetic process
FNV58_14165	COG1968	undecaprenyl-diphosphatase activity
FNV58_14190	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_14210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV58_14220	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FNV58_14230	COG2318	DinB family
FNV58_14245	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FNV58_14250	COG0747	negative chemotaxis
FNV58_14255	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_14285	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FNV58_14295	COG1760	l-serine dehydratase
FNV58_14300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNV58_14305	COG0509	glycine decarboxylation via glycine cleavage system
FNV58_14345	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FNV58_14365	COG4175	Glycine betaine
FNV58_14365	COG0517	IMP dehydrogenase activity
FNV58_14390	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FNV58_14400	COG4638	Rieske (2fe-2S)
FNV58_14405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNV58_14415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV58_14455	COG0697	spore germination
FNV58_14530	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FNV58_14530	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FNV58_14540	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FNV58_14560	COG1716	ATPase activity
FNV58_14580	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FNV58_14615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNV58_14630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV58_14635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV58_14645	COG2816	NAD+ diphosphatase activity
FNV58_14650	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FNV58_14660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNV58_14665	COG3706	GGDEF domain
FNV58_14670	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FNV58_14675	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNV58_14695	COG2018	Roadblock/LC7 domain
FNV58_14750	COG4336	lyase activity
FNV58_14755	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FNV58_14760	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FNV58_14765	COG1984	allophanate hydrolase subunit 2
FNV58_14770	COG2755	lipolytic protein G-D-S-L family
FNV58_14775	COG0438	transferase activity, transferring glycosyl groups
FNV58_14780	COG0438	transferase activity, transferring glycosyl groups
FNV58_14805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV58_14820	COG2270	Major facilitator Superfamily
FNV58_14835	COG0463	Glycosyl transferase, family 2
FNV58_14870	COG1960	acyl-CoA dehydrogenase activity
FNV58_14880	COG1309	transcriptional regulator
FNV58_14925	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FNV58_14930	COG0140	phosphoribosyl-ATP diphosphatase activity
FNV58_14935	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FNV58_14940	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNV58_14940	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNV58_14945	COG3201	nicotinamide mononucleotide transporter
FNV58_14955	COG1846	Transcriptional regulator
FNV58_14955	COG1940	carbohydrate kinase activity
FNV58_14960	COG2223	nitrite transmembrane transporter activity
FNV58_14975	COG2233	PERMEase
FNV58_15000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FNV58_15020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNV58_15025	COG3842	ATPase activity
FNV58_15035	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNV58_15045	COG2188	Transcriptional regulator
FNV58_15055	COG0531	amino acid
FNV58_15075	COG2390	Transcriptional regulator
FNV58_15080	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FNV58_15090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNV58_15110	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FNV58_15125	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FNV58_15140	COG0194	GDP metabolic process
FNV58_15150	COG0284	orotidine-5'-phosphate decarboxylase activity
FNV58_15155	COG0167	dihydroorotate dehydrogenase activity
FNV58_15160	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FNV58_15165	COG0505	Belongs to the CarA family
FNV58_15175	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FNV58_15180	COG0540	Belongs to the ATCase OTCase family
FNV58_15185	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FNV58_15195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FNV58_15200	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FNV58_15205	COG0006	proline dipeptidase activity
FNV58_15215	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FNV58_15220	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FNV58_15225	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FNV58_15230	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FNV58_15235	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FNV58_15245	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FNV58_15250	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FNV58_15270	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FNV58_15285	COG1131	(ABC) transporter
FNV58_15295	COG4585	Histidine kinase
FNV58_15300	COG2197	response regulator
FNV58_15305	COG0124	histidyl-tRNA synthetase
FNV58_15315	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FNV58_15320	COG1196	nuclear chromosome segregation
FNV58_15325	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FNV58_15335	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FNV58_15340	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FNV58_15345	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FNV58_15355	COG2255	four-way junction helicase activity
FNV58_15360	COG0632	four-way junction helicase activity
FNV58_15365	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FNV58_15370	COG0217	transcriptional regulatory protein
FNV58_15375	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FNV58_15380	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FNV58_15400	COG0438	transferase activity, transferring glycosyl groups
FNV58_15430	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FNV58_15435	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FNV58_15450	COG5002	protein histidine kinase activity
FNV58_15450	COG2176	DNA-directed DNA polymerase activity
FNV58_15480	COG0395	ABC-type sugar transport system, permease component
FNV58_15485	COG1175	transmembrane transport
FNV58_15535	COG0512	Glutamine amidotransferase of anthranilate synthase
FNV58_15535	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FNV58_15595	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FNV58_15595	COG1648	precorrin-2 dehydrogenase activity
FNV58_15600	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FNV58_15615	COG1464	Belongs to the NlpA lipoprotein family
FNV58_15620	COG2011	ABC-type metal ion transport system permease component
FNV58_15625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FNV58_15660	COG0318	PFAM AMP-dependent synthetase and ligase
FNV58_15660	COG0204	Acyl-transferase
FNV58_15665	COG0477	Major facilitator Superfamily
FNV58_15680	COG0165	Argininosuccinate lyase
FNV58_15685	COG0137	argininosuccinate synthase activity
FNV58_15705	COG2205	protein histidine kinase activity
FNV58_15710	COG0745	RESPONSE REGULATOR receiver
FNV58_15740	COG1438	arginine binding
FNV58_15745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FNV58_15750	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FNV58_15755	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FNV58_15760	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FNV58_15780	COG0789	Transcriptional regulator
FNV58_15815	COG0697	spore germination
FNV58_15825	COG1649	PFAM Uncharacterised BCR, COG1649
FNV58_15840	COG1051	belongs to the nudix hydrolase family
FNV58_15855	COG0072	phenylalanine-tRNA ligase activity
FNV58_15855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNV58_15860	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FNV58_15865	COG5002	protein histidine kinase activity
FNV58_15870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNV58_15875	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FNV58_15880	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FNV58_15885	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FNV58_15940	COG1012	belongs to the aldehyde dehydrogenase family
FNV58_15945	COG0174	glutamine synthetase
FNV58_15955	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FNV58_15995	COG4176	ABC-type proline glycine betaine transport system permease component
FNV58_16000	COG0517	IMP dehydrogenase activity
FNV58_16000	COG4175	Glycine betaine
FNV58_16005	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNV58_16035	COG0564	pseudouridine synthase activity
FNV58_16065	COG1309	transcriptional regulator
FNV58_16105	COG0805	protein transport
FNV58_16110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNV58_16140	COG0545	Peptidyl-prolyl cis-trans isomerase
FNV58_16145	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FNV58_16155	COG1609	Transcriptional regulator
FNV58_16160	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FNV58_16165	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FNV58_16180	COG4122	O-methyltransferase activity
FNV58_16185	COG1222	aaa ATPase
FNV58_16210	COG0517	IMP dehydrogenase activity
FNV58_16210	COG1994	Peptidase M50
FNV58_16220	COG2197	response regulator
FNV58_16230	COG4166	transmembrane transport
FNV58_16240	COG1410	methionine synthase
FNV58_16240	COG0646	methionine synthase
FNV58_16245	COG1414	Transcriptional regulator
FNV58_16250	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FNV58_16255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNV58_16260	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FNV58_16265	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FNV58_16275	COG1129	ABC transporter
FNV58_16285	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FNV58_16290	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FNV58_16295	COG0235	Class ii aldolase
FNV58_16300	COG0235	Class ii aldolase
FNV58_16300	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FNV58_16305	COG2186	Transcriptional regulator
FNV58_16330	COG0215	cysteine-tRNA ligase activity
FNV58_16350	COG0598	Magnesium transport protein CorA
FNV58_16360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV58_16365	COG0667	Aldo Keto reductase
FNV58_16395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNV58_16410	COG0308	aminopeptidase N
FNV58_16415	COG3012	SEC-C Motif Domain Protein
FNV58_16420	COG2186	Transcriptional regulator
FNV58_16425	COG3265	gluconokinase activity
FNV58_16435	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_16440	COG1063	alcohol dehydrogenase
FNV58_16465	COG3573	Dehydrogenase
FNV58_16475	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FNV58_16480	COG2149	membrane
FNV58_16510	COG0318	PFAM AMP-dependent synthetase and ligase
FNV58_16520	COG3876	Protein conserved in bacteria
FNV58_16540	COG0072	phenylalanine-tRNA ligase activity
FNV58_16540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNV58_16545	COG0789	Transcriptional regulator
FNV58_16565	COG1960	acyl-CoA dehydrogenase activity
FNV58_16575	COG0640	Transcriptional regulator
FNV58_16580	COG0697	spore germination
FNV58_16605	COG2851	Citrate transporter
FNV58_16610	COG0243	molybdopterin cofactor binding
FNV58_16615	COG1309	transcriptional regulator
FNV58_16625	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FNV58_16665	COG1595	DNA-templated transcription, initiation
FNV58_16685	COG0515	serine threonine protein kinase
FNV58_16685	COG2815	serine threonine protein kinase
FNV58_16690	COG2755	lipolytic protein G-D-S-L family
FNV58_16710	COG1649	PFAM Uncharacterised BCR, COG1649
FNV58_16710	COG0726	polysaccharide deacetylase
FNV58_16735	COG1725	Transcriptional regulator
FNV58_16775	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FNV58_16775	COG0662	Cupin 2, conserved barrel domain protein
FNV58_16780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FNV58_16785	COG0587	DNA-directed DNA polymerase activity
FNV58_16795	COG0330	HflC and HflK could
FNV58_16820	COG1126	abc transporter atp-binding protein
FNV58_16830	COG0765	amino acid transport
FNV58_16845	COG1799	cell septum assembly
FNV58_16850	COG1960	acyl-CoA dehydrogenase activity
FNV58_16855	COG0477	Major facilitator Superfamily
FNV58_16865	COG0671	phosphoesterase, PA-phosphatase related
FNV58_16875	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FNV58_16905	COG1129	ABC transporter
FNV58_16935	COG1160	GTP binding
FNV58_16945	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FNV58_16985	COG3541	Predicted nucleotidyltransferase
FNV58_17000	COG1187	pseudouridine synthase activity
FNV58_17005	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FNV58_17010	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FNV58_17025	COG0686	Belongs to the AlaDH PNT family
FNV58_17035	COG0494	nUDIX hydrolase
FNV58_17040	COG0504	CTP synthase activity
FNV58_17045	COG3387	PFAM Glycoside hydrolase 15-related
FNV58_17070	COG0497	DNA recombination
FNV58_17075	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FNV58_17095	COG1120	ATPase activity
FNV58_17100	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNV58_17105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNV58_17110	COG0647	UMP catabolic process
FNV58_17150	COG2094	Belongs to the DNA glycosylase MPG family
FNV58_17160	COG1881	PFAM PEBP family protein
FNV58_17180	COG1119	ATPase activity
FNV58_17205	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_17210	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FNV58_17220	COG1131	(ABC) transporter
FNV58_17220	COG1716	ATPase activity
FNV58_17220	COG0842	Transport permease protein
FNV58_17230	COG0560	Phosphoserine phosphatase
FNV58_17230	COG3830	Belongs to the UPF0237 family
FNV58_17250	COG2186	Transcriptional regulator
FNV58_17260	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FNV58_17265	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_17280	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FNV58_17300	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FNV58_17305	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV58_17325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV58_17375	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FNV58_17390	COG3387	PFAM Glycoside hydrolase 15-related
FNV58_17440	COG0488	(ABC) transporter
FNV58_17470	COG0235	Class ii aldolase
FNV58_17490	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FNV58_17495	COG1492	cobalamin metabolic process
FNV58_17510	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FNV58_17515	COG1797	cobyrinic acid a,c-diamide synthase activity
FNV58_17580	COG0765	amino acid transport
FNV58_17585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV58_17590	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FNV58_17595	COG0456	acetyltransferase
FNV58_17600	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FNV58_17605	COG1917	Cupin 2, conserved barrel domain protein
FNV58_17610	COG5285	phytanoyl-CoA dioxygenase
FNV58_17615	COG3844	kynureninase activity
FNV58_17640	COG1414	Transcriptional regulator
FNV58_17650	COG0768	penicillin binding
FNV58_17655	COG2252	PERMEase
FNV58_17660	COG1595	DNA-templated transcription, initiation
FNV58_17675	COG4733	cellulase activity
FNV58_17715	COG4677	pectinesterase activity
FNV58_17720	COG3866	Pectate lyase
FNV58_17725	COG2755	lipolytic protein G-D-S-L family
FNV58_17730	COG1653	transport
FNV58_17765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV58_17770	COG1802	Transcriptional regulator
FNV58_17795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNV58_17800	COG1349	DNA-binding transcription factor activity
FNV58_17815	COG0395	ABC-type sugar transport system, permease component
FNV58_17820	COG1063	alcohol dehydrogenase
FNV58_17830	COG1309	transcriptional regulator
FNV58_17845	COG1802	Transcriptional regulator
FNV58_17885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV58_17900	COG3973	AAA domain
FNV58_17915	COG2171	N-acyltransferase activity
FNV58_17920	COG3226	Transcriptional regulator
FNV58_17925	COG2076	Multidrug Resistance protein
FNV58_17940	COG2151	metal-sulfur cluster biosynthetic enzyme
FNV58_17945	COG0822	iron-sulfur transferase activity
FNV58_17950	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FNV58_17955	COG0396	ATPase activity
FNV58_17965	COG0719	Fe-S assembly protein
FNV58_17980	COG2746	aminoglycoside 3-N-acetyltransferase activity
FNV58_17985	COG1131	(ABC) transporter
FNV58_18010	COG0109	protoheme IX farnesyltransferase activity
FNV58_18025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FNV58_18040	COG0363	glucosamine-6-phosphate deaminase activity
FNV58_18045	COG0395	ABC-type sugar transport system, permease component
FNV58_18050	COG1175	transmembrane transport
FNV58_18060	COG0366	Alpha amylase catalytic
FNV58_18065	COG1653	transport
FNV58_18070	COG1695	Transcriptional regulator
FNV58_18075	COG1136	(ABC) transporter
FNV58_18090	COG0166	Belongs to the GPI family
FNV58_18105	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FNV58_18110	COG0149	triose-phosphate isomerase activity
FNV58_18115	COG0126	phosphoglycerate kinase activity
FNV58_18120	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FNV58_18130	COG1481	regulation of sporulation
FNV58_18135	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FNV58_18140	COG1660	Displays ATPase and GTPase activities
FNV58_18145	COG0322	excinuclease ABC activity
FNV58_18160	COG1609	Transcriptional regulator
FNV58_18170	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FNV58_18185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV58_18190	COG0765	amino acid transport
FNV58_18200	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FNV58_18205	COG0477	Major facilitator Superfamily
FNV58_18210	COG0387	Pfam Sodium calcium exchanger
FNV58_18230	COG0556	nucleotide-excision repair
FNV58_18240	COG0584	glycerophosphoryl diester phosphodiesterase
FNV58_18245	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FNV58_18265	COG2313	pseudouridylate synthase activity
FNV58_18275	COG2226	methyltransferase
FNV58_18280	COG0598	Magnesium transport protein CorA
FNV58_18310	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV58_18315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV58_18355	COG0402	S-adenosylhomocysteine deaminase activity
FNV58_18380	COG1201	RNA secondary structure unwinding
FNV58_18430	COG2856	Zn peptidase
FNV58_18495	COG1953	Uracil, thiamine, allantoin
FNV58_18500	COG1802	Transcriptional regulator
FNV58_18505	COG2267	carboxylic ester hydrolase activity
FNV58_18515	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FNV58_18545	COG0237	dephospho-CoA kinase activity
FNV58_18555	COG1231	oxidoreductase activity
FNV58_18565	COG2226	methyltransferase
FNV58_18570	COG1643	Atp-dependent helicase
FNV58_18610	COG2050	protein possibly involved in aromatic compounds catabolism
FNV58_18620	COG0559	Belongs to the binding-protein-dependent transport system permease family
FNV58_18630	COG0411	ABC transporter
FNV58_18635	COG0410	ABC transporter
FNV58_18670	COG0737	Belongs to the 5'-nucleotidase family
FNV58_18690	COG4566	intracellular signal transduction
FNV58_18695	COG1605	Chorismate mutase
FNV58_18695	COG0287	Prephenate dehydrogenase
FNV58_18730	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_18735	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_18740	COG1024	Enoyl-CoA hydratase
FNV58_18765	COG0183	Belongs to the thiolase family
FNV58_18770	COG1309	transcriptional regulator
FNV58_18780	COG1960	acyl-CoA dehydrogenase activity
FNV58_18785	COG1960	acyl-CoA dehydrogenase activity
FNV58_18790	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNV58_18800	COG2304	oxidoreductase activity
FNV58_18815	COG1136	(ABC) transporter
FNV58_18815	COG4591	ABC-type transport system involved in lipoprotein release permease component
FNV58_18830	COG0577	efflux transmembrane transporter activity
FNV58_18830	COG1136	(ABC) transporter
FNV58_18840	COG0070	glutamate synthase
FNV58_18840	COG0069	glutamate synthase activity
FNV58_18840	COG0067	glutamate synthase
FNV58_18870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV58_18875	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV58_18880	COG2301	Belongs to the HpcH HpaI aldolase family
FNV58_18885	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FNV58_18895	COG0159	tryptophan synthase activity
FNV58_18900	COG0133	tryptophan synthase activity
FNV58_18910	COG0134	indole-3-glycerol-phosphate synthase activity
FNV58_18935	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FNV58_18955	COG0107	imidazoleglycerol-phosphate synthase activity
FNV58_18960	COG0251	oxidation-reduction process
FNV58_18965	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FNV58_18970	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FNV58_18975	COG0131	Imidazoleglycerol-phosphate dehydratase
FNV58_18980	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNV58_18985	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FNV58_19005	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FNV58_19025	COG1432	Conserved Protein
FNV58_19030	COG0587	DNA-directed DNA polymerase activity
FNV58_19090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FNV58_19095	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FNV58_19105	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FNV58_19110	COG3599	regulation of cell shape
FNV58_19120	COG1799	cell septum assembly
FNV58_19135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FNV58_19150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FNV58_19160	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FNV58_19165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNV58_19175	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FNV58_19180	COG0768	penicillin binding
FNV58_19190	COG0275	rRNA processing
FNV58_19200	COG0714	Associated with various cellular activities
FNV58_19220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FNV58_19240	COG1309	transcriptional regulator
FNV58_19265	COG0352	thiamine-phosphate diphosphorylase activity
FNV58_19285	COG2022	thiamine diphosphate biosynthetic process
FNV58_19285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV58_19295	COG2022	thiamine diphosphate biosynthetic process
FNV58_19300	COG0515	serine threonine protein kinase
FNV58_19300	COG2815	serine threonine protein kinase
FNV58_19305	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FNV58_19310	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FNV58_19315	COG2193	ferroxidase activity
FNV58_19320	COG0243	molybdopterin cofactor binding
FNV58_19325	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FNV58_19345	COG0205	6-phosphofructokinase activity
FNV58_19355	COG4585	Histidine kinase
FNV58_19380	COG1940	carbohydrate kinase activity
FNV58_19390	COG0003	Pfam Anion-transporting ATPase
FNV58_19430	COG0534	Mate efflux family protein
FNV58_19450	COG1388	LysM domain
FNV58_19450	COG0791	NLP P60 protein
FNV58_19450	COG3103	Sh3 type 3 domain protein
FNV58_19475	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FNV58_19480	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FNV58_19485	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNV58_19490	COG0723	plastoquinol--plastocyanin reductase activity
FNV58_19495	COG2010	Cytochrome c
FNV58_19500	COG1845	cytochrome c oxidase, subunit III
FNV58_19520	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FNV58_19525	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FNV58_19560	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FNV58_19565	COG2197	response regulator
FNV58_19590	COG2226	methyltransferase
FNV58_19595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNV58_19615	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FNV58_19620	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FNV58_19620	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FNV58_19635	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FNV58_19640	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FNV58_19645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNV58_19650	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV58_19665	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FNV58_19695	COG0454	-acetyltransferase
FNV58_19715	COG0321	lipoyl(octanoyl) transferase activity
FNV58_19720	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FNV58_19740	COG0174	glutamine synthetase
FNV58_19750	COG0501	Belongs to the peptidase M48B family
FNV58_19800	COG0745	RESPONSE REGULATOR receiver
FNV58_19815	COG2197	response regulator
FNV58_19845	COG1309	transcriptional regulator
FNV58_19880	COG1175	transmembrane transport
FNV58_19885	COG3833	ABC-type maltose transport systems, permease component
FNV58_19890	COG0366	Alpha amylase catalytic
FNV58_19895	COG1609	Transcriptional regulator
FNV58_19905	COG0583	DNA-binding transcription factor activity
FNV58_19910	COG0697	spore germination
FNV58_19915	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FNV58_19920	COG3511	phospholipase C
FNV58_19960	COG0174	glutamine synthetase
FNV58_19965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FNV58_19965	COG1017	nitric oxide dioxygenase activity
FNV58_19970	COG1959	2 iron, 2 sulfur cluster binding
FNV58_19990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FNV58_19990	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FNV58_19995	COG2814	Major facilitator Superfamily
FNV58_20010	COG0477	Major facilitator Superfamily
FNV58_20015	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FNV58_20035	COG1994	Peptidase M50
FNV58_20095	COG2822	iron ion transport
FNV58_20100	COG2837	iron assimilation
FNV58_20105	COG0672	)-iron permease
FNV58_20115	COG0495	leucyl-tRNA aminoacylation
FNV58_20125	COG1834	amidinotransferase
FNV58_20135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV58_20140	COG2814	Major facilitator Superfamily
FNV58_20165	COG1136	(ABC) transporter
FNV58_20170	COG0667	Aldo Keto reductase
FNV58_20180	COG2259	Doxx family
FNV58_20195	COG0406	alpha-ribazole phosphatase activity
FNV58_20205	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_20210	COG0673	inositol 2-dehydrogenase activity
FNV58_20220	COG0583	DNA-binding transcription factor activity
FNV58_20245	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FNV58_20275	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FNV58_20350	COG3022	response to hydroperoxide
FNV58_20355	COG0800	Aldolase
FNV58_20370	COG0406	alpha-ribazole phosphatase activity
FNV58_20370	COG0328	RNA-DNA hybrid ribonuclease activity
FNV58_20380	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FNV58_20395	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_20410	COG1131	(ABC) transporter
FNV58_20420	COG4585	Histidine kinase
FNV58_20430	COG2197	response regulator
FNV58_20450	COG0183	Belongs to the thiolase family
FNV58_20455	COG0477	Major facilitator Superfamily
FNV58_20475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV58_20510	COG1309	transcriptional regulator
FNV58_20570	COG3845	ABC transporter
FNV58_20590	COG3619	membrane
FNV58_20615	COG0183	Belongs to the thiolase family
FNV58_20620	COG2124	cytochrome p450
FNV58_20720	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNV58_20725	COG1335	isochorismatase
FNV58_20730	COG0477	Major facilitator Superfamily
FNV58_20750	COG1733	regulation of RNA biosynthetic process
FNV58_20855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNV58_20870	COG1358	cellular component organization or biogenesis
FNV58_20920	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FNV58_20925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNV58_20930	COG0477	Major facilitator Superfamily
FNV58_20935	COG1309	transcriptional regulator
FNV58_20950	COG0667	Aldo Keto reductase
FNV58_20955	COG0789	Transcriptional regulator
FNV58_20970	COG1741	Belongs to the pirin family
FNV58_20985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNV58_20990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV58_20995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV58_21025	COG1309	transcriptional regulator
FNV58_21040	COG2084	Dehydrogenase
FNV58_21075	COG1764	response to oxidative stress
FNV58_21080	COG2130	NADP-dependent
FNV58_21110	COG4213	ABC transporter substrate-binding protein
FNV58_21120	COG4214	carbohydrate transport
FNV58_21130	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNV58_21165	COG1764	response to oxidative stress
FNV58_21195	COG0596	Alpha beta hydrolase
FNV58_21215	COG2318	DinB family
FNV58_21240	COG3507	Belongs to the glycosyl hydrolase 43 family
FNV58_21245	COG0395	ABC-type sugar transport system, permease component
FNV58_21250	COG1175	transmembrane transport
FNV58_21260	COG3386	PFAM SMP-30 Gluconolaconase
FNV58_21265	COG1414	Transcriptional regulator
FNV58_21290	COG4981	capsule polysaccharide biosynthetic process
FNV58_21365	COG0318	PFAM AMP-dependent synthetase and ligase
FNV58_21370	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FNV58_21370	COG0825	malonyl-CoA metabolic process
FNV58_21375	COG1404	Belongs to the peptidase S8 family
FNV58_21380	COG1077	Cell shape determining protein MreB Mrl
FNV58_21425	COG0559	Belongs to the binding-protein-dependent transport system permease family
FNV58_21435	COG0410	ABC transporter
FNV58_21445	COG0318	PFAM AMP-dependent synthetase and ligase
FNV58_21480	COG1070	Carbohydrate kinase
FNV58_21495	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FNV58_21500	COG0358	DNA primase activity
FNV58_21510	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FNV58_21520	COG2949	membrane
FNV58_21585	COG2146	nitrite reductase [NAD(P)H] activity
FNV58_21585	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNV58_21595	COG1309	transcriptional regulator
FNV58_21600	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_21615	COG1136	(ABC) transporter
FNV58_21635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNV58_21635	COG0574	Belongs to the PEP-utilizing enzyme family
FNV58_21640	COG1846	Transcriptional regulator
FNV58_21640	COG1940	carbohydrate kinase activity
FNV58_21675	COG0477	Major facilitator Superfamily
FNV58_21705	COG0667	Aldo Keto reductase
FNV58_21715	COG1309	transcriptional regulator
FNV58_21720	COG0300	oxidoreductase activity
FNV58_21725	COG0423	glycine-tRNA ligase activity
FNV58_21730	COG0803	Belongs to the bacterial solute-binding protein 9 family
FNV58_21735	COG1121	(ABC) transporter
FNV58_21740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FNV58_21750	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FNV58_21755	COG1381	Involved in DNA repair and RecF pathway recombination
FNV58_21765	COG0515	serine threonine protein kinase
FNV58_21765	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNV58_21805	COG0456	acetyltransferase
FNV58_21810	COG2197	response regulator
FNV58_21815	COG4585	Histidine kinase
FNV58_21820	COG1131	(ABC) transporter
FNV58_21835	COG2186	Transcriptional regulator
FNV58_21840	COG0747	negative chemotaxis
FNV58_21850	COG0444	Belongs to the ABC transporter superfamily
FNV58_21855	COG4608	Belongs to the ABC transporter superfamily
FNV58_21860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV58_21875	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNV58_21940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FNV58_21960	COG2315	Protein conserved in bacteria
FNV58_21970	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FNV58_21990	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV58_21995	COG1234	tRNA 3'-trailer cleavage
FNV58_22000	COG0537	adenosine 5'-monophosphoramidase activity
FNV58_22005	COG4946	Tricorn protease homolog
FNV58_22005	COG0793	Belongs to the peptidase S41A family
FNV58_22030	COG0484	heat shock protein binding
FNV58_22035	COG1420	regulation of RNA biosynthetic process
FNV58_22075	COG0481	GTPase activity
FNV58_22080	COG0268	Binds directly to 16S ribosomal RNA
FNV58_22140	COG1555	photosystem II stabilization
FNV58_22140	COG1596	polysaccharide export
FNV58_22145	COG1307	EDD domain protein, DegV family
FNV58_22155	COG0495	leucyl-tRNA aminoacylation
FNV58_22195	COG0477	Major facilitator Superfamily
FNV58_22210	COG0588	phosphoglycerate mutase activity
FNV58_22215	COG0799	negative regulation of ribosome biogenesis
FNV58_22225	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FNV58_22230	COG0501	Belongs to the peptidase M48B family
FNV58_22245	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FNV58_22255	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FNV58_22265	COG0438	transferase activity, transferring glycosyl groups
FNV58_22270	COG0463	Glycosyl transferase, family 2
FNV58_22270	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNV58_22275	COG0463	Glycosyl transferase, family 2
FNV58_22275	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNV58_22290	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FNV58_22295	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FNV58_22300	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FNV58_22305	COG1530	ribonuclease E activity
FNV58_22335	COG1309	transcriptional regulator
FNV58_22340	COG0300	oxidoreductase activity
FNV58_22365	COG0640	Transcriptional regulator
FNV58_22370	COG2226	methyltransferase
FNV58_22380	COG0477	Major facilitator Superfamily
FNV58_22415	COG0772	Belongs to the SEDS family
FNV58_22420	COG0768	penicillin binding
FNV58_22435	COG1077	Cell shape determining protein MreB Mrl
FNV58_22440	COG0105	UTP biosynthetic process
FNV58_22450	COG0285	dihydrofolate synthase activity
FNV58_22455	COG0525	valine-tRNA ligase activity
FNV58_22465	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FNV58_22470	COG0740	serine-type endopeptidase activity
FNV58_22475	COG0740	serine-type endopeptidase activity
FNV58_22480	COG0544	peptidyl-prolyl cis-trans isomerase activity
FNV58_22505	COG3594	Acyltransferase
FNV58_22520	COG4552	Acetyltransferase involved in intracellular survival and related
FNV58_22535	COG1113	amino acid transport
FNV58_22540	COG0515	serine threonine protein kinase
FNV58_22550	COG1268	BioY protein
FNV58_22555	COG1940	carbohydrate kinase activity
FNV58_22565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV58_22570	COG1116	anion transmembrane transporter activity
FNV58_22585	COG1113	amino acid transport
FNV58_22590	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FNV58_22595	COG0588	phosphoglycerate mutase activity
FNV58_22605	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FNV58_22640	COG0346	lactoylglutathione lyase activity
FNV58_22685	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FNV58_22720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV58_22745	COG2826	transposase and inactivated derivatives, IS30 family
FNV58_22750	COG1122	ATPase activity
FNV58_22775	COG0668	transmembrane transport
FNV58_22805	COG1653	transport
FNV58_22810	COG1175	transmembrane transport
FNV58_22815	COG0395	ABC-type sugar transport system, permease component
FNV58_22820	COG1486	melibiose metabolic process
FNV58_22835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV58_22865	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FNV58_22870	COG2346	COG2346, Truncated hemoglobins
FNV58_22915	COG0489	protein tyrosine kinase activity
FNV58_22935	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FNV58_22960	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FNV58_22990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNV58_23000	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FNV58_23050	COG0629	single-stranded DNA binding
FNV58_23155	COG3962	Belongs to the TPP enzyme family
FNV58_23160	COG3718	enzyme involved in inositol metabolism
FNV58_23170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV58_23195	COG2409	Drug exporters of the RND superfamily
FNV58_23225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FNV58_23245	COG1129	ABC transporter
FNV58_23250	COG1879	ABC-type sugar transport system periplasmic component
FNV58_23255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV58_23260	COG1869	D-ribose catabolic process
FNV58_23280	COG0673	inositol 2-dehydrogenase activity
FNV58_23285	COG1609	Transcriptional regulator
FNV58_23290	COG1846	Transcriptional regulator
FNV58_23290	COG0456	acetyltransferase
FNV58_23300	COG0181	hydroxymethylbilane synthase activity
FNV58_23305	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FNV58_23310	COG1472	Belongs to the glycosyl hydrolase 3 family
FNV58_23350	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNV58_23355	COG2356	endonuclease I
FNV58_23360	COG0028	Belongs to the TPP enzyme family
FNV58_23370	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV58_23390	COG1946	Acyl-CoA thioesterase
FNV58_23400	COG1309	transcriptional regulator
FNV58_23405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV58_23420	COG1960	acyl-CoA dehydrogenase activity
FNV58_23455	COG0076	glutamate decarboxylase activity
FNV58_23460	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FNV58_23495	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNV58_23505	COG0589	response to stress
FNV58_23520	COG4977	sequence-specific DNA binding
FNV58_23525	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FNV58_23560	COG0395	ABC-type sugar transport system, permease component
FNV58_23575	COG3979	chitinase
FNV58_23585	COG0745	RESPONSE REGULATOR receiver
FNV58_23610	COG0406	alpha-ribazole phosphatase activity
FNV58_23660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV58_23695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV58_23700	COG0765	amino acid transport
FNV58_23705	COG0765	amino acid transport
FNV58_23710	COG1126	abc transporter atp-binding protein
FNV58_23725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV58_23740	COG1362	aminopeptidase activity
FNV58_23760	COG0318	PFAM AMP-dependent synthetase and ligase
FNV58_23770	COG3397	chitin binding
FNV58_23845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV58_23850	COG2188	Transcriptional regulator
FNV58_23865	COG0673	inositol 2-dehydrogenase activity
FNV58_23870	COG4702	Belongs to the UPF0303 family
FNV58_23880	COG0706	membrane insertase activity
FNV58_23880	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion
FNV58_23890	COG1733	regulation of RNA biosynthetic process
FNV58_23900	COG3764	Sortase (surface protein transpeptidase)
FNV58_23910	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FNV58_23970	COG3250	beta-galactosidase activity
FNV58_23985	COG1846	Transcriptional regulator
FNV58_24015	COG2733	membrane
FNV58_24030	COG1131	(ABC) transporter
FNV58_24045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNV58_24080	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FNV58_24090	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FNV58_24095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNV58_24095	COG1263	PTS System
FNV58_24100	COG1263	PTS System
FNV58_24100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNV58_24105	COG1263	PTS System
FNV58_24105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNV58_24120	COG3631	Ketosteroid isomerase-related protein
FNV58_24165	COG1113	amino acid transport
FNV58_24180	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FNV58_24190	COG1335	isochorismatase
FNV58_24200	COG4412	M6 family metalloprotease domain protein
FNV58_24200	COG3291	Pkd domain containing protein
FNV58_24225	COG0277	FAD linked oxidase domain protein
FNV58_24235	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FNV58_24245	COG1174	glycine betaine transport
FNV58_24265	COG3480	Lon protease (S16) C-terminal proteolytic domain
FNV58_24270	COG4948	Mandelate Racemase Muconate Lactonizing
FNV58_24280	COG0049	tRNA binding
FNV58_24300	COG0531	amino acid
FNV58_24350	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FNV58_24360	COG1175	transmembrane transport
FNV58_24365	COG1653	transport
FNV58_24375	COG1678	Uncharacterized ACR, COG1678
FNV58_24380	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FNV58_24385	COG0776	regulation of translation
FNV58_24395	COG3973	AAA domain
FNV58_24425	COG2223	nitrite transmembrane transporter activity
FNV58_24445	COG0583	DNA-binding transcription factor activity
FNV58_24470	COG1501	Belongs to the glycosyl hydrolase 31 family
FNV58_24500	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FNV58_24505	COG0793	Belongs to the peptidase S41A family
FNV58_24515	COG2884	Cell division ATP-binding protein ftsE
FNV58_24530	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FNV58_24535	COG0515	serine threonine protein kinase
FNV58_24540	COG0515	serine threonine protein kinase
FNV58_24565	COG0395	ABC-type sugar transport system, permease component
FNV58_24570	COG0463	Glycosyl transferase, family 2
FNV58_24570	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNV58_24575	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNV58_24595	COG1764	response to oxidative stress
FNV58_24600	COG1846	Transcriptional regulator
FNV58_24615	COG1216	Glycosyl transferase, family 2
FNV58_24640	COG2197	response regulator
FNV58_24665	COG1134	teichoic acid transport
FNV58_24670	COG0438	transferase activity, transferring glycosyl groups
FNV58_24675	COG0463	Glycosyl transferase, family 2
FNV58_24675	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNV58_24685	COG2902	Dehydrogenase
FNV58_24710	COG0653	protein targeting
FNV58_24720	COG3214	Protein conserved in bacteria
FNV58_24725	COG2197	response regulator
FNV58_24730	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FNV58_24740	COG0823	Involved in the tonB-independent uptake of proteins
FNV58_24745	COG5000	phosphorelay sensor kinase activity
FNV58_24745	COG5002	protein histidine kinase activity
FNV58_24750	COG0745	RESPONSE REGULATOR receiver
FNV58_24755	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FNV58_24775	COG0714	Associated with various cellular activities
FNV58_24820	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FNV58_24830	COG1482	cell wall glycoprotein biosynthetic process
FNV58_24840	COG2835	tetraacyldisaccharide 4'-kinase activity
FNV58_24845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNV58_24895	COG0778	Nitroreductase
FNV58_24895	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
FNV58_24905	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FNV58_24925	COG1316	TRANSCRIPTIONal
FNV58_24945	COG1316	TRANSCRIPTIONal
FNV58_24955	COG1011	Hydrolase
FNV58_24970	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FNV58_25015	COG2205	protein histidine kinase activity
FNV58_25020	COG0745	RESPONSE REGULATOR receiver
FNV58_25025	COG3104	oligopeptide transport
FNV58_25080	COG1366	Belongs to the anti-sigma-factor antagonist family
FNV58_25085	COG1191	sigma factor activity
FNV58_25095	COG1228	amidohydrolase
FNV58_25105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNV58_25110	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FNV58_25155	COG2986	histidine ammonia-lyase
FNV58_25165	COG1174	glycine betaine transport
FNV58_25170	COG1174	glycine betaine transport
FNV58_25180	COG1609	Transcriptional regulator
FNV58_25195	COG0288	reversible hydration of carbon dioxide
FNV58_25215	COG0183	Belongs to the thiolase family
FNV58_25260	COG0577	efflux transmembrane transporter activity
FNV58_25260	COG1136	(ABC) transporter
FNV58_25265	COG0577	efflux transmembrane transporter activity
FNV58_25270	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FNV58_25275	COG1252	NADH dehydrogenase
FNV58_25295	COG0148	phosphopyruvate hydratase activity
FNV58_25305	COG1652	LysM domain
FNV58_25310	COG2124	cytochrome p450
FNV58_25430	COG1309	transcriptional regulator
FNV58_25445	COG1136	(ABC) transporter
FNV58_25445	COG0577	efflux transmembrane transporter activity
FNV58_25450	COG1136	(ABC) transporter
FNV58_25455	COG0477	Major facilitator Superfamily
FNV58_25465	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV58_25495	COG4585	Histidine kinase
FNV58_25510	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FNV58_25515	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FNV58_25520	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FNV58_25525	COG0193	aminoacyl-tRNA hydrolase activity
FNV58_25535	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FNV58_25545	COG1309	transcriptional regulator
FNV58_25555	COG4106	trans-aconitate 2-methyltransferase activity
FNV58_25560	COG1846	Transcriptional regulator
FNV58_25565	COG2197	response regulator
FNV58_25575	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FNV58_25620	COG0488	(ABC) transporter
FNV58_25630	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FNV58_25635	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FNV58_25645	COG0084	hydrolase, TatD family'
FNV58_25675	COG3224	Antibiotic biosynthesis monooxygenase
FNV58_25680	COG0590	tRNA wobble adenosine to inosine editing
FNV58_25685	COG0768	penicillin binding
FNV58_25710	COG0310	cobalt ion transport
FNV58_25720	COG1122	ATPase activity
FNV58_25725	COG1846	Transcriptional regulator
FNV58_25730	COG1764	response to oxidative stress
FNV58_25755	COG0667	Aldo Keto reductase
FNV58_25765	COG2409	Drug exporters of the RND superfamily
FNV58_25775	COG4946	Tricorn protease homolog
FNV58_25775	COG0793	Belongs to the peptidase S41A family
FNV58_25785	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_25790	COG2267	carboxylic ester hydrolase activity
FNV58_25795	COG2072	flavoprotein involved in K transport
FNV58_25805	COG0708	Exodeoxyribonuclease III
FNV58_25825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNV58_25830	COG0521	Mo-molybdopterin cofactor biosynthetic process
FNV58_25830	COG0315	cyclic pyranopterin monophosphate synthase activity
FNV58_25835	COG0315	cyclic pyranopterin monophosphate synthase activity
FNV58_25845	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FNV58_25850	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FNV58_25860	COG3263	regulation of cellular component size
FNV58_25880	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FNV58_25890	COG1970	mechanosensitive ion channel activity
FNV58_25925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNV58_25925	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNV58_25925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNV58_25935	COG1349	DNA-binding transcription factor activity
FNV58_25945	COG0477	Major facilitator Superfamily
FNV58_25965	COG1247	-acetyltransferase
FNV58_25970	COG3384	dioxygenase
FNV58_25975	COG1846	Transcriptional regulator
FNV58_26000	COG1414	Transcriptional regulator
FNV58_26005	COG0477	Major facilitator Superfamily
FNV58_26060	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV58_26080	COG2197	response regulator
FNV58_26085	COG4585	Histidine kinase
FNV58_26140	COG2843	Capsule synthesis protein
FNV58_26145	COG2197	response regulator
FNV58_26175	COG2197	response regulator
FNV58_26180	COG4585	Histidine kinase
FNV58_26205	COG0277	FAD linked oxidase domain protein
FNV58_26215	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNV58_26250	COG0386	Belongs to the glutathione peroxidase family
FNV58_26265	COG1686	Belongs to the peptidase S11 family
FNV58_26320	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FNV58_26340	COG1733	regulation of RNA biosynthetic process
FNV58_26350	COG4221	oxidoreductase activity
FNV58_26355	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_26360	COG2267	carboxylic ester hydrolase activity
FNV58_26390	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FNV58_26415	COG3903	Transcriptional regulator
FNV58_26415	COG3629	intracellular signal transduction
FNV58_26430	COG0318	PFAM AMP-dependent synthetase and ligase
FNV58_26445	COG1024	Enoyl-CoA hydratase
FNV58_26450	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNV58_26450	COG0515	serine threonine protein kinase
FNV58_26460	COG1309	transcriptional regulator
FNV58_26470	COG1960	acyl-CoA dehydrogenase activity
FNV58_26480	COG2226	methyltransferase
FNV58_26485	COG0259	pyridoxamine-phosphate oxidase activity
FNV58_26530	COG0045	succinate-CoA ligase (ADP-forming) activity
FNV58_26535	COG1024	Enoyl-CoA hydratase
FNV58_26540	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV58_26560	COG1960	acyl-CoA dehydrogenase activity
FNV58_26565	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_26585	COG1960	acyl-CoA dehydrogenase activity
FNV58_26590	COG1960	acyl-CoA dehydrogenase activity
FNV58_26600	COG0318	PFAM AMP-dependent synthetase and ligase
FNV58_26615	COG1595	DNA-templated transcription, initiation
FNV58_26665	COG2267	carboxylic ester hydrolase activity
FNV58_26675	COG4821	SIS domain
FNV58_26700	COG0259	pyridoxamine-phosphate oxidase activity
FNV58_26710	COG1024	Enoyl-CoA hydratase
FNV58_26715	COG0318	PFAM AMP-dependent synthetase and ligase
FNV58_26730	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV58_26765	COG1132	(ABC) transporter
FNV58_26770	COG0277	FAD linked oxidase domain protein
FNV58_26770	COG0247	lactate metabolic process
FNV58_26795	COG2124	cytochrome p450
FNV58_26805	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FNV58_26825	COG0789	Transcriptional regulator
FNV58_26835	COG0667	Aldo Keto reductase
FNV58_26850	COG1846	Transcriptional regulator
FNV58_26860	COG2252	PERMEase
FNV58_26870	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FNV58_26900	COG2814	Major facilitator Superfamily
FNV58_26910	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FNV58_26915	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FNV58_26920	COG1278	Cold shock
FNV58_26945	COG1061	Type III restriction enzyme res subunit
FNV58_26960	COG3973	AAA domain
FNV58_26965	COG3142	Participates in the control of copper homeostasis
FNV58_27000	COG1737	Transcriptional regulator
FNV58_27005	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FNV58_27010	COG1263	PTS System
FNV58_27010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNV58_27050	COG2084	Dehydrogenase
FNV58_27065	COG0459	protein refolding
FNV58_27085	COG0463	Glycosyl transferase, family 2
FNV58_27120	COG1105	Belongs to the carbohydrate kinase PfkB family
FNV58_27140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV58_27180	COG0308	aminopeptidase N
FNV58_27210	COG0723	plastoquinol--plastocyanin reductase activity
FNV58_27210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV58_27260	COG3842	ATPase activity
FNV58_27280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNV58_27285	COG0215	cysteine-tRNA ligase activity
FNV58_27290	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FNV58_27295	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FNV58_27300	COG1329	Transcriptional regulator
FNV58_27320	COG5002	protein histidine kinase activity
FNV58_27360	COG0588	phosphoglycerate mutase activity
FNV58_27390	COG0438	transferase activity, transferring glycosyl groups
FNV58_27425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV58_27430	COG1090	epimerase
FNV58_27435	COG1595	DNA-templated transcription, initiation
FNV58_27445	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_27455	COG1309	transcriptional regulator
FNV58_27460	COG1063	alcohol dehydrogenase
FNV58_27505	COG4552	Acetyltransferase involved in intracellular survival and related
FNV58_27520	COG1490	D-aminoacyl-tRNA deacylase activity
FNV58_27525	COG0354	folic acid binding
FNV58_27535	COG3485	protocatechuate 3,4-dioxygenase
FNV58_27575	COG2897	thiosulfate sulfurtransferase activity
FNV58_27605	COG0745	RESPONSE REGULATOR receiver
FNV58_27610	COG1609	Transcriptional regulator
FNV58_27645	COG0745	RESPONSE REGULATOR receiver
FNV58_27650	COG1132	(ABC) transporter
FNV58_27655	COG0737	Belongs to the 5'-nucleotidase family
FNV58_27660	COG0456	acetyltransferase
FNV58_27675	COG1131	(ABC) transporter
FNV58_27690	COG1725	Transcriptional regulator
FNV58_27695	COG1131	(ABC) transporter
FNV58_27710	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FNV58_27740	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FNV58_27745	COG0306	phosphate transporter
FNV58_27755	COG1937	Protein conserved in bacteria
FNV58_27770	COG0277	FAD linked oxidase domain protein
FNV58_27775	COG0671	phosphoesterase, PA-phosphatase related
FNV58_27780	COG0739	heme binding
FNV58_27780	COG1196	nuclear chromosome segregation
FNV58_27780	COG0741	lytic transglycosylase activity
FNV58_27890	COG1252	NADH dehydrogenase
FNV58_27900	COG0366	Alpha amylase catalytic
FNV58_27900	COG1470	cell adhesion involved in biofilm formation
FNV58_27920	COG0579	oxidoreductase
FNV58_27925	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FNV58_27935	COG0667	Aldo Keto reductase
FNV58_27960	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNV58_27960	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNV58_27970	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNV58_27990	COG0513	Belongs to the DEAD box helicase family
FNV58_28030	COG1643	Atp-dependent helicase
FNV58_28065	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FNV58_28085	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FNV58_28090	COG0047	phosphoribosylformylglycinamidine synthase activity
FNV58_28095	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FNV58_28125	COG3850	Histidine kinase
FNV58_28130	COG2197	response regulator
FNV58_28140	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FNV58_28155	COG0151	Belongs to the GarS family
FNV58_28240	COG0433	COG0433 Predicted ATPase
FNV58_28255	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FNV58_28290	COG1191	sigma factor activity
FNV58_28295	COG1191	sigma factor activity
FNV58_28310	COG1846	Transcriptional regulator
FNV58_28325	COG3467	pyridoxamine 5'-phosphate
FNV58_28335	COG0477	Major facilitator Superfamily
FNV58_28340	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNV58_28350	COG2205	protein histidine kinase activity
FNV58_28355	COG0745	RESPONSE REGULATOR receiver
FNV58_28365	COG2329	Antibiotic biosynthesis monooxygenase
FNV58_28380	COG1846	Transcriptional regulator
FNV58_28425	COG0318	PFAM AMP-dependent synthetase and ligase
FNV58_28430	COG1595	DNA-templated transcription, initiation
FNV58_28445	COG1960	acyl-CoA dehydrogenase activity
FNV58_28455	COG1960	acyl-CoA dehydrogenase activity
FNV58_28485	COG2318	DinB family
FNV58_28515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNV58_28535	COG0653	protein targeting
FNV58_28555	COG0006	proline dipeptidase activity
FNV58_28570	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FNV58_28590	COG2409	Drug exporters of the RND superfamily
FNV58_28595	COG4585	Histidine kinase
FNV58_28630	COG2837	iron assimilation
FNV58_28640	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FNV58_28645	COG0561	phosphatase activity
FNV58_28675	COG1131	(ABC) transporter
FNV58_28685	COG0789	Transcriptional regulator
FNV58_28690	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FNV58_28700	COG0561	phosphatase activity
FNV58_28710	COG4988	ABC transporter
FNV58_28715	COG1294	oxidase, subunit
FNV58_28720	COG1271	oxidase subunit
FNV58_28725	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNV58_28730	COG1609	Transcriptional regulator
FNV58_28750	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FNV58_28775	COG0662	Cupin 2, conserved barrel domain protein
FNV58_28780	COG1950	PFAM Membrane protein of
FNV58_28785	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNV58_28790	COG0626	cystathionine gamma-synthase activity
FNV58_28825	COG2814	Major facilitator Superfamily
FNV58_28845	COG0305	Participates in initiation and elongation during chromosome replication
FNV58_28860	COG0359	binds to the 23S rRNA
FNV58_28865	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FNV58_28870	COG0629	single-stranded DNA binding
FNV58_28875	COG0360	Binds together with S18 to 16S ribosomal RNA
FNV58_28900	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FNV58_28925	COG0617	tRNA 3'-terminal CCA addition
FNV58_28945	COG1595	DNA-templated transcription, initiation
FNV58_28955	COG0492	ferredoxin-NADP+ reductase activity
FNV58_28960	COG3118	belongs to the thioredoxin family
FNV58_28975	COG1192	Involved in chromosome partitioning
FNV58_28980	COG0357	Ribosomal RNA small subunit methyltransferase G
FNV58_28990	COG0706	membrane insertase activity
FNV58_28995	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FNV58_29000	COG0594	ribonuclease P activity
FNV58_29005	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FNV58_29010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FNV58_29020	COG0592	DNA-directed DNA polymerase activity
FNV58_29025	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FNV58_29030	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FNV58_29035	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FNV58_29040	COG0187	DNA topoisomerase II activity
FNV58_29045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FNV58_29080	COG0515	serine threonine protein kinase
FNV58_29105	COG0705	Rhomboid family
FNV58_29120	COG3764	Sortase (surface protein transpeptidase)
FNV58_29135	COG3764	Sortase (surface protein transpeptidase)
FNV58_29140	COG3764	Sortase (surface protein transpeptidase)
FNV58_29145	COG0515	serine threonine protein kinase
FNV58_29155	COG0768	penicillin binding
FNV58_29170	COG1716	ATPase activity
FNV58_29175	COG1716	ATPase activity
FNV58_29200	COG0745	RESPONSE REGULATOR receiver
FNV58_29215	COG4770	biotin carboxylase activity
FNV58_29230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV58_29275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV58_29305	COG0475	glutathione-regulated potassium exporter activity
FNV58_29315	COG1733	regulation of RNA biosynthetic process
FNV58_29320	COG0477	Major facilitator Superfamily
FNV58_29340	COG0277	FAD linked oxidase domain protein
FNV58_29360	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FNV58_29365	COG1733	regulation of RNA biosynthetic process
FNV58_29410	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV58_29420	COG1522	sequence-specific DNA binding
FNV58_29440	COG0746	molybdenum cofactor guanylyltransferase activity
FNV58_29470	COG0515	serine threonine protein kinase
FNV58_29475	COG0515	serine threonine protein kinase
FNV58_29500	COG0022	dehydrogenase e1 component
FNV58_29505	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV58_29560	COG1362	aminopeptidase activity
FNV58_29565	COG1960	acyl-CoA dehydrogenase activity
FNV58_29575	COG1741	Belongs to the pirin family
FNV58_29590	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FNV58_29620	COG3866	Pectate lyase
FNV58_29630	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNV58_29650	COG1289	transmembrane transporter activity
FNV58_29660	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNV58_29665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV58_29695	COG2205	protein histidine kinase activity
FNV58_29700	COG0745	RESPONSE REGULATOR receiver
FNV58_29715	COG1653	transport
FNV58_29720	COG1473	amidohydrolase
FNV58_29735	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FNV58_29745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNV58_29785	COG1278	Cold shock
FNV58_29820	COG0725	ABC transporter, periplasmic molybdate-binding protein
FNV58_29870	COG0515	serine threonine protein kinase
FNV58_29870	COG2815	serine threonine protein kinase
FNV58_29885	COG1595	DNA-templated transcription, initiation
FNV58_29895	COG0561	phosphatase activity
FNV58_29945	COG0745	RESPONSE REGULATOR receiver
FNV58_29950	COG5002	protein histidine kinase activity
FNV58_29960	COG2409	Drug exporters of the RND superfamily
FNV58_29965	COG4585	Histidine kinase
FNV58_29970	COG2197	response regulator
FNV58_29990	COG0640	Transcriptional regulator
FNV58_29995	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FNV58_30005	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FNV58_30010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNV58_30080	COG2326	polyphosphate kinase activity
FNV58_30085	COG3387	PFAM Glycoside hydrolase 15-related
FNV58_30090	COG0477	Major facilitator Superfamily
FNV58_30120	COG1063	alcohol dehydrogenase
FNV58_30160	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FNV58_30180	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNV58_30180	COG0515	serine threonine protein kinase
FNV58_30205	COG1733	regulation of RNA biosynthetic process
FNV58_30235	COG2205	protein histidine kinase activity
FNV58_30240	COG0745	RESPONSE REGULATOR receiver
FNV58_30310	COG0717	Belongs to the dCTP deaminase family
FNV58_30335	COG0247	lactate metabolic process
FNV58_30335	COG2181	nitrate reductase activity
FNV58_30340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNV58_30345	COG0443	Heat shock 70 kDa protein
FNV58_30350	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FNV58_30355	COG0484	heat shock protein binding
FNV58_30360	COG0789	Transcriptional regulator
FNV58_30370	COG4213	ABC transporter substrate-binding protein
FNV58_30395	COG1305	Transglutaminase-like
FNV58_30440	COG0542	response to heat
FNV58_30475	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FNV58_30490	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FNV58_30495	COG0191	fructose-bisphosphate aldolase activity
FNV58_30515	COG3844	kynureninase activity
FNV58_30540	COG4585	Histidine kinase
FNV58_30545	COG2197	response regulator
FNV58_30550	COG4585	Histidine kinase
FNV58_30555	COG2197	response regulator
FNV58_30570	COG3559	Exporter of polyketide antibiotics
FNV58_30575	COG1131	(ABC) transporter
FNV58_30590	COG4303	Ethanolamine ammonia lyase large subunit
FNV58_30605	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FNV58_30610	COG0737	Belongs to the 5'-nucleotidase family
FNV58_30620	COG1802	Transcriptional regulator
FNV58_30630	COG0693	protein deglycase activity
FNV58_30660	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FNV58_30665	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FNV58_30700	COG5002	protein histidine kinase activity
FNV58_30700	COG5000	phosphorelay sensor kinase activity
FNV58_30825	COG4152	abc transporter atp-binding protein
FNV58_30885	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FNV58_30900	COG1132	(ABC) transporter
FNV58_30925	COG1408	metallophosphoesterase
FNV58_30950	COG0003	Pfam Anion-transporting ATPase
FNV58_30975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV58_31005	COG0596	Alpha beta hydrolase
FNV58_31015	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FNV58_31020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV58_31025	COG0659	secondary active sulfate transmembrane transporter activity
FNV58_31085	COG1205	dead DEAH box helicase
FNV58_31085	COG1111	helicase
FNV58_31090	COG1366	Belongs to the anti-sigma-factor antagonist family
FNV58_31095	COG2172	sigma factor antagonist activity
FNV58_31100	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FNV58_31115	COG2815	serine threonine protein kinase
FNV58_31115	COG0515	serine threonine protein kinase
FNV58_31125	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FNV58_31125	COG1754	DNA topoisomerase type I activity
FNV58_31130	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FNV58_31135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FNV58_31275	COG2197	response regulator
FNV58_31345	COG3629	intracellular signal transduction
FNV58_31345	COG3903	Transcriptional regulator
FNV58_31350	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNV58_31350	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNV58_31375	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FNV58_31380	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FNV58_31385	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FNV58_31390	COG0254	rRNA binding
FNV58_31400	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FNV58_31420	COG1012	belongs to the aldehyde dehydrogenase family
FNV58_31440	COG0076	glutamate decarboxylase activity
FNV58_31450	COG0789	Transcriptional regulator
FNV58_31455	COG0393	Putative heavy-metal-binding
FNV58_31470	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FNV58_31485	COG0037	tRNA processing
FNV58_31500	COG0302	gtp cyclohydrolase
FNV58_31515	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FNV58_31530	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FNV58_31530	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FNV58_31555	COG0649	NAD binding
FNV58_31575	COG2197	response regulator
FNV58_31580	COG1660	Displays ATPase and GTPase activities
FNV58_31605	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FNV58_31610	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FNV58_31620	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FNV58_31640	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FNV58_31660	COG0542	response to heat
FNV58_31670	COG0739	heme binding
FNV58_31690	COG2205	protein histidine kinase activity
FNV58_31695	COG0745	RESPONSE REGULATOR receiver
FNV58_31705	COG1595	DNA-templated transcription, initiation
FNV58_31720	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FNV58_31740	COG0248	Ppx GppA phosphatase
FNV58_31745	COG1082	Xylose isomerase domain protein TIM barrel
FNV58_31750	COG1309	transcriptional regulator
FNV58_31755	COG0129	dihydroxy-acid dehydratase activity
FNV58_31760	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNV58_31760	COG0515	serine threonine protein kinase
FNV58_31770	COG4991	sh3 domain protein
FNV58_31780	COG2226	methyltransferase
FNV58_31790	COG1129	ABC transporter
FNV58_31790	COG0842	Transport permease protein
FNV58_31800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FNV58_31805	COG0180	Tryptophanyl-tRNA synthetase
FNV58_31845	COG0123	including yeast histone deacetylase and acetoin utilization protein
FNV58_31885	COG0560	Phosphoserine phosphatase
FNV58_31895	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FNV58_31900	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FNV58_31905	COG0181	hydroxymethylbilane synthase activity
FNV58_31910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FNV58_31910	COG1648	precorrin-2 dehydrogenase activity
FNV58_31915	COG0113	porphobilinogen synthase activity
FNV58_31945	COG0018	arginyl-trna synthetase
FNV58_31950	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FNV58_31970	COG1690	Belongs to the RtcB family
FNV58_31990	COG1742	UPF0060 membrane protein
FNV58_32000	COG1846	Transcriptional regulator
FNV58_32005	COG1733	regulation of RNA biosynthetic process
FNV58_32020	COG0583	DNA-binding transcription factor activity
FNV58_32035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV58_32065	COG0531	amino acid
FNV58_32075	COG1136	(ABC) transporter
FNV58_32085	COG2197	response regulator
FNV58_32100	COG0501	Belongs to the peptidase M48B family
FNV58_32110	COG1968	undecaprenyl-diphosphatase activity
FNV58_32135	COG0531	amino acid
FNV58_32155	COG0598	Magnesium transport protein CorA
FNV58_32160	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV58_32175	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNV58_32180	COG0406	alpha-ribazole phosphatase activity
FNV58_32200	COG1333	cytochrome c biogenesis protein
FNV58_32205	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FNV58_32250	COG2226	methyltransferase
FNV58_32260	COG0640	Transcriptional regulator
FNV58_32280	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FNV58_32285	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FNV58_32290	COG0163	prenyltransferase activity
FNV58_32300	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FNV58_32315	COG1309	transcriptional regulator
FNV58_32330	COG0183	Belongs to the thiolase family
FNV58_32345	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FNV58_32360	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FNV58_32380	COG0726	polysaccharide deacetylase
FNV58_32390	COG2226	methyltransferase
FNV58_32420	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV58_32425	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV58_32430	COG0649	NAD binding
FNV58_32440	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FNV58_32445	COG1034	ATP synthesis coupled electron transport
FNV58_32450	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FNV58_32455	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV58_32465	COG0713	ATP synthesis coupled electron transport
FNV58_32470	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FNV58_32480	COG1007	ATP synthesis coupled electron transport
FNV58_32485	COG0514	ATP-dependent DNA helicase (RecQ)
FNV58_32490	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FNV58_32495	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FNV58_32500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV58_32515	COG2188	Transcriptional regulator
FNV58_32535	COG0492	ferredoxin-NADP+ reductase activity
FNV58_32545	COG5280	Phage tail tape measure protein TP901
FNV58_32545	COG3953	SLT domain
FNV58_32575	COG1131	(ABC) transporter
FNV58_32585	COG0655	NAD(P)H dehydrogenase (quinone) activity
FNV58_32610	COG0702	epimerase
FNV58_32615	COG1733	regulation of RNA biosynthetic process
FNV58_32620	COG1013	pyruvate-flavodoxin oxidoreductase activity
FNV58_32625	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FNV58_32625	COG0674	pyruvate-flavodoxin oxidoreductase activity
FNV58_32645	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV58_32650	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV58_32655	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV58_32660	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FNV58_32665	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNV58_32670	COG0839	Belongs to the complex I subunit 6 family
FNV58_32675	COG0713	ATP synthesis coupled electron transport
FNV58_32690	COG1007	ATP synthesis coupled electron transport
FNV58_32695	COG0501	Belongs to the peptidase M48B family
FNV58_32700	COG3304	Inner membrane component domain
FNV58_32720	COG2261	transglycosylase associated protein
FNV58_32725	COG1666	GTP binding
FNV58_32805	COG2188	Transcriptional regulator
FNV58_32830	COG0702	epimerase
FNV58_32835	COG0402	S-adenosylhomocysteine deaminase activity
FNV58_32850	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FNV58_32855	COG2030	dehydratase
FNV58_32870	COG0477	Major facilitator Superfamily
FNV58_32875	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FNV58_32880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNV58_32895	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV58_32900	COG0436	Aminotransferase
FNV58_32920	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FNV58_32925	COG0081	regulation of translation
FNV58_32940	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FNV58_32945	COG0222	ribosome binding
FNV58_32955	COG0085	RNA polymerase activity
FNV58_32960	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FNV58_32990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNV58_32995	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FNV58_33000	COG0049	tRNA binding
FNV58_33005	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FNV58_33010	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FNV58_33025	COG2124	cytochrome p450
FNV58_33045	COG1404	Belongs to the peptidase S8 family
FNV58_33080	COG0051	transcription antitermination factor activity, RNA binding
FNV58_33085	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FNV58_33090	COG0088	Forms part of the polypeptide exit tunnel
FNV58_33095	COG0089	rRNA binding
FNV58_33100	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FNV58_33105	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FNV58_33110	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FNV58_33115	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FNV58_33120	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FNV58_33125	COG0255	Belongs to the universal ribosomal protein uL29 family
FNV58_33130	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FNV58_33135	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FNV58_33140	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FNV58_33145	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FNV58_33150	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FNV58_33160	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FNV58_33165	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FNV58_33170	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FNV58_33175	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FNV58_33180	COG1841	ribosomal large subunit assembly
FNV58_33185	COG0200	Binds to the 23S rRNA
FNV58_33195	COG0563	adenylate kinase activity
FNV58_33205	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FNV58_33210	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FNV58_33215	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FNV58_33220	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FNV58_33225	COG0202	RNA polymerase activity
FNV58_33230	COG0203	ribosomal protein L17
FNV58_33235	COG0101	tRNA pseudouridine synthase activity
FNV58_33245	COG1215	transferase activity, transferring glycosyl groups
FNV58_33265	COG0463	Glycosyl transferase, family 2
FNV58_33275	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FNV58_33280	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FNV58_33285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNV58_33290	COG1072	(Pantothenic acid kinase))
FNV58_33295	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNV58_33340	COG0736	holo-[acyl-carrier-protein] synthase activity
FNV58_33355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FNV58_33365	COG0802	atpase or kinase
FNV58_33385	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FNV58_33395	COG1609	Transcriptional regulator
FNV58_33410	COG0395	ABC-type sugar transport system, permease component
FNV58_33415	COG1472	Belongs to the glycosyl hydrolase 3 family
FNV58_33420	COG1609	Transcriptional regulator
FNV58_33445	COG4941	Belongs to the sigma-70 factor family
FNV58_33455	COG0726	polysaccharide deacetylase
FNV58_33460	COG0726	polysaccharide deacetylase
FNV58_33470	COG0459	protein refolding
FNV58_33480	COG4221	oxidoreductase activity
FNV58_33490	COG0583	DNA-binding transcription factor activity
FNV58_33505	COG1595	DNA-templated transcription, initiation
FNV58_33515	COG0516	GMP reductase activity
FNV58_33530	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FNV58_33550	COG0515	serine threonine protein kinase
FNV58_33555	COG0515	serine threonine protein kinase
FNV58_33555	COG2815	serine threonine protein kinase
FNV58_33560	COG0515	serine threonine protein kinase
FNV58_33565	COG1012	belongs to the aldehyde dehydrogenase family
FNV58_33590	COG0519	Catalyzes the synthesis of GMP from XMP
FNV58_33590	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FNV58_33635	COG2197	response regulator
FNV58_33670	COG0739	heme binding
FNV58_33695	COG0714	Associated with various cellular activities
FNV58_33700	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FNV58_33705	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FNV58_33720	COG0045	succinate-CoA ligase (ADP-forming) activity
FNV58_33755	COG0138	bifunctional purine biosynthesis protein purh
FNV58_33775	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FNV58_33800	COG0039	L-malate dehydrogenase activity
FNV58_33820	COG1846	Transcriptional regulator
FNV58_33820	COG0456	acetyltransferase
FNV58_33835	COG4175	Glycine betaine
FNV58_33835	COG0517	IMP dehydrogenase activity
FNV58_33840	COG4176	ABC-type proline glycine betaine transport system permease component
FNV58_33855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV58_33860	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV58_33870	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV58_33880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV58_33890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV58_33895	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FNV58_33895	COG0512	Glutamine amidotransferase of anthranilate synthase
FNV58_33900	COG3224	Antibiotic biosynthesis monooxygenase
FNV58_33920	COG0754	glutathionylspermidine amidase activity
FNV58_33925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FNV58_33930	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNV58_33940	COG0180	Tryptophanyl-tRNA synthetase
FNV58_33975	COG1295	ribonuclease BN
FNV58_33990	COG1408	metallophosphoesterase
FNV58_34010	COG2205	protein histidine kinase activity
FNV58_34015	COG0745	RESPONSE REGULATOR receiver
FNV58_34020	COG2409	Drug exporters of the RND superfamily
FNV58_34065	COG1053	succinate dehydrogenase
FNV58_34075	COG2009	succinate dehydrogenase
FNV58_34085	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FNV58_34120	COG1595	DNA-templated transcription, initiation
FNV58_34125	COG1595	DNA-templated transcription, initiation
FNV58_34140	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV58_34140	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNV58_34155	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNV58_34165	COG1216	Glycosyl transferase, family 2
FNV58_34180	COG2089	acid synthase
FNV58_34195	COG0573	inorganic phosphate transmembrane transporter activity
FNV58_34230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FNV58_34235	COG4195	phage-related replication protein
FNV58_34290	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FNV58_34290	COG1473	amidohydrolase
FNV58_34295	COG1744	ABC transporter substrate-binding protein PnrA-like
FNV58_34300	COG1744	ABC transporter substrate-binding protein PnrA-like
FNV58_34345	COG0592	DNA-directed DNA polymerase activity
FNV58_34350	COG2814	Major facilitator Superfamily
FNV58_34355	COG0583	DNA-binding transcription factor activity
FNV58_34365	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV58_34390	COG2205	protein histidine kinase activity
FNV58_34395	COG0745	RESPONSE REGULATOR receiver
FNV58_34400	COG1595	DNA-templated transcription, initiation
FNV58_34415	COG1012	belongs to the aldehyde dehydrogenase family
FNV58_34420	COG1012	belongs to the aldehyde dehydrogenase family
FNV58_34480	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FNV58_34495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNV58_34525	COG4770	biotin carboxylase activity
FNV58_34535	COG0424	maF-like protein
FNV58_34550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV58_34560	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FNV58_34570	COG1024	Enoyl-CoA hydratase
FNV58_34580	COG2986	histidine ammonia-lyase
FNV58_34585	COG1278	Cold shock
FNV58_34620	COG1136	(ABC) transporter
FNV58_34630	COG1404	Belongs to the peptidase S8 family
FNV58_34645	COG1064	alcohol dehydrogenase
FNV58_34650	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNV58_34655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNV58_34665	COG2132	Multicopper oxidase
FNV58_34705	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FNV58_34715	COG3173	Aminoglycoside phosphotransferase
FNV58_34740	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNV58_34765	COG2255	four-way junction helicase activity
FNV58_34770	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FNV58_34815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FNV58_34825	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV58_34850	COG1331	Highly conserved protein containing a thioredoxin domain
FNV58_34880	COG1309	transcriptional regulator
FNV58_34885	COG0477	Major facilitator Superfamily
FNV58_34895	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FNV58_34995	COG0436	Aminotransferase
FNV58_35010	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FNV58_35025	COG1414	Transcriptional regulator
FNV58_35030	COG0251	oxidation-reduction process
FNV58_35035	COG2610	gluconate transmembrane transporter activity
FNV58_35095	COG2894	cell division
FNV58_35125	COG2197	response regulator
FNV58_35145	COG2885	chlorophyll binding
FNV58_35150	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNV58_35180	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FNV58_35190	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FNV58_35205	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV58_35210	COG0450	alkyl hydroperoxide reductase
FNV58_35225	COG1136	(ABC) transporter
FNV58_35245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNV58_35275	COG0114	fumarate hydratase activity
FNV58_35295	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FNV58_35295	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FNV58_35320	COG0778	Nitroreductase
FNV58_35325	COG1722	exodeoxyribonuclease VII activity
FNV58_35330	COG1570	exodeoxyribonuclease VII activity
FNV58_35335	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FNV58_35350	COG0012	GTP binding
FNV58_35440	COG1053	succinate dehydrogenase
FNV58_35465	COG0747	negative chemotaxis
FNV58_35475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNV58_35480	COG0444	Belongs to the ABC transporter superfamily
FNV58_35485	COG4608	Belongs to the ABC transporter superfamily
FNV58_35490	COG0346	lactoylglutathione lyase activity
FNV58_35500	COG0601	transmembrane transport
FNV58_35505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNV58_35510	COG0444	Belongs to the ABC transporter superfamily
FNV58_35515	COG4608	Belongs to the ABC transporter superfamily
FNV58_35530	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV58_35550	COG1131	(ABC) transporter
FNV58_35560	COG4585	Histidine kinase
FNV58_35565	COG2197	response regulator
FNV58_35600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNV58_35610	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FNV58_35620	COG0519	Catalyzes the synthesis of GMP from XMP
FNV58_35625	COG1024	Enoyl-CoA hydratase
FNV58_35640	COG1595	DNA-templated transcription, initiation
FNV58_35655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNV58_35680	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FNV58_35690	COG0598	Magnesium transport protein CorA
FNV58_35700	COG2814	Major facilitator Superfamily
FNV58_35715	COG2095	MarC family integral membrane protein
FNV58_35725	COG1432	Conserved Protein
FNV58_35730	COG0596	Alpha beta hydrolase
FNV58_35775	COG0747	negative chemotaxis
FNV58_35785	COG0601	transmembrane transport
FNV58_35825	COG0596	Alpha beta hydrolase
FNV58_35845	COG0210	DNA helicase
FNV58_35850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNV58_35890	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FNV58_35945	COG3480	Lon protease (S16) C-terminal proteolytic domain
FNV58_35955	COG1615	UPF0182 protein
FNV58_35980	COG0753	catalase activity
FNV58_35985	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FNV58_35985	COG0517	IMP dehydrogenase activity
FNV58_35990	COG0483	inositol monophosphate 1-phosphatase activity
FNV58_36000	COG2076	Multidrug Resistance protein
FNV58_36010	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FNV58_36020	COG2135	peptidase activity
FNV58_36030	COG1595	DNA-templated transcription, initiation
FNV58_36035	COG5662	AntiSigma factor
FNV58_36040	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FNV58_36040	COG2199	diguanylate cyclase activity
FNV58_36055	COG0242	peptide deformylase activity
FNV58_36065	COG2124	cytochrome p450
FNV58_36085	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNV58_36110	COG2188	Transcriptional regulator
FNV58_36130	COG1472	Belongs to the glycosyl hydrolase 3 family
FNV58_36135	COG0363	glucosamine-6-phosphate deaminase activity
FNV58_36140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNV58_36155	COG1597	lipid kinase activity
FNV58_36200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNV58_36280	COG1126	abc transporter atp-binding protein
FNV58_36300	COG0281	malic enzyme
FNV58_36305	COG0604	alcohol dehydrogenase
FNV58_36340	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV58_36340	COG0567	Dehydrogenase, E1 component
FNV58_36345	COG2205	protein histidine kinase activity
FNV58_36350	COG0745	RESPONSE REGULATOR receiver
FNV58_36380	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FNV58_36465	COG0701	Predicted permease
FNV58_36470	COG0768	penicillin binding
FNV58_36475	COG0772	Belongs to the SEDS family
FNV58_36485	COG2205	protein histidine kinase activity
FNV58_36510	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNV58_36520	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNV58_36625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FNV58_36760	COG0018	arginyl-trna synthetase
FNV58_36765	COG0019	diaminopimelate decarboxylase activity
FNV58_36770	COG0460	homoserine dehydrogenase
FNV58_36775	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FNV58_36780	COG0083	homoserine kinase activity
FNV58_36795	COG1316	TRANSCRIPTIONal
FNV58_36800	COG0254	rRNA binding
FNV58_36805	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FNV58_36810	COG2890	protein-(glutamine-N5) methyltransferase activity
FNV58_36820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNV58_36830	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNV58_36835	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNV58_36850	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FNV58_36855	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FNV58_36860	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FNV58_36865	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FNV58_36870	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FNV58_36875	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FNV58_36880	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FNV58_36895	COG2197	response regulator
FNV58_36920	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV58_36940	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
FNV58_36985	COG1131	(ABC) transporter
FNV58_37005	COG0183	Belongs to the thiolase family
FNV58_37040	COG2814	Major facilitator Superfamily
FNV58_37125	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FNV58_37130	COG0280	phosphate acetyltransferase
FNV58_37130	COG0857	belongs to the CobB CobQ family
FNV58_37135	COG0205	6-phosphofructokinase activity
FNV58_37155	COG1175	transmembrane transport
FNV58_37180	COG4565	transcriptional regulatory protein
FNV58_37185	COG3290	protein histidine kinase activity
FNV58_37190	COG1301	dicarboxylic acid transport
FNV58_37200	COG0477	Major facilitator Superfamily
FNV58_37215	COG1522	sequence-specific DNA binding
FNV58_37235	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FNV58_37240	COG3281	Trehalose synthase
FNV58_37250	COG0366	Alpha amylase catalytic
FNV58_37260	COG0058	SHG alpha-glucan phosphorylase activity
FNV58_37280	COG1132	(ABC) transporter
FNV58_37285	COG1132	(ABC) transporter
FNV58_37290	COG1132	(ABC) transporter
FNV58_37295	COG1132	(ABC) transporter
FNV58_37300	COG1131	(ABC) transporter
FNV58_37310	COG4585	Histidine kinase
FNV58_37315	COG2197	response regulator
FNV58_37325	COG1376	ErfK ybiS ycfS ynhG family protein
FNV58_37330	COG1376	ErfK ybiS ycfS ynhG family protein
FNV58_37380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNV58_37405	COG0475	glutathione-regulated potassium exporter activity
FNV58_37410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV58_37425	COG3629	intracellular signal transduction
FNV58_37425	COG3903	Transcriptional regulator
FNV58_37455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV58_37480	COG2267	carboxylic ester hydrolase activity
FNV58_37485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV58_37490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV58_37495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV58_37500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV58_37515	COG1233	COG1233 Phytoene dehydrogenase and related
FNV58_37545	COG3251	PFAM MbtH domain protein
FNV58_37550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV58_37550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV58_37560	COG0277	FAD linked oxidase domain protein
FNV58_37575	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNV58_37580	COG1760	l-serine dehydratase
FNV58_37585	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNV58_37590	COG0509	glycine decarboxylation via glycine cleavage system
FNV58_37595	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FNV58_37630	COG0444	Belongs to the ABC transporter superfamily
FNV58_37635	COG4608	Belongs to the ABC transporter superfamily
FNV58_37650	COG2860	membrane
FNV58_37670	COG2378	regulation of single-species biofilm formation
FNV58_37710	COG0482	sulfurtransferase activity
FNV58_37720	COG1611	Belongs to the LOG family
FNV58_37725	COG4221	oxidoreductase activity
FNV58_37735	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FNV58_37745	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FNV58_37750	COG0154	amidase activity
FNV58_37760	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FNV58_37765	COG2409	Drug exporters of the RND superfamily
FNV58_37770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNV58_37785	COG2197	response regulator
FNV58_37795	COG2133	pyrroloquinoline quinone binding
FNV58_37800	COG0667	Aldo Keto reductase
FNV58_37810	COG5001	Diguanylate cyclase
FNV58_37820	COG0440	acetolactate synthase activity
FNV58_37825	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FNV58_37835	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FNV58_37835	COG1672	PFAM Archaeal ATPase
FNV58_37840	COG0477	Major facilitator Superfamily
FNV58_37860	COG3214	Protein conserved in bacteria
FNV58_37870	COG0506	proline dehydrogenase activity
FNV58_37875	COG1012	belongs to the aldehyde dehydrogenase family
FNV58_37890	COG1082	Xylose isomerase domain protein TIM barrel
FNV58_37900	COG0477	Major facilitator Superfamily
FNV58_37915	COG0473	3-isopropylmalate dehydrogenase activity
FNV58_37920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FNV58_37940	COG0832	Belongs to the urease beta subunit family
FNV58_37940	COG0831	urea catabolic process
FNV58_37945	COG0804	urea catabolic process
FNV58_37950	COG2957	Belongs to the agmatine deiminase family
FNV58_37960	COG0477	Major facilitator Superfamily
FNV58_37965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNV58_37995	COG2197	response regulator
FNV58_38005	COG1131	(ABC) transporter
FNV58_38040	COG4585	Histidine kinase
FNV58_38050	COG2353	YceI-like domain
FNV58_38055	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV58_38075	COG2018	Roadblock/LC7 domain
FNV58_38095	COG2018	Roadblock/LC7 domain
FNV58_38100	COG5002	protein histidine kinase activity
FNV58_38110	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNV58_38115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FNV58_38165	COG1414	Transcriptional regulator
FNV58_38170	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FNV58_38175	COG0066	3-isopropylmalate dehydratase activity
FNV58_38185	COG0776	regulation of translation
FNV58_38205	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FNV58_38210	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNV58_38235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FNV58_38240	COG1461	Dihydroxyacetone kinase
FNV58_38250	COG0326	Molecular chaperone. Has ATPase activity
FNV58_38260	COG0742	ribosomal rna small subunit methyltransferase
FNV58_38265	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FNV58_38280	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FNV58_38285	COG0571	ribonuclease III activity
FNV58_38290	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FNV58_38295	COG1733	regulation of RNA biosynthetic process
FNV58_38310	COG2815	serine threonine protein kinase
FNV58_38310	COG0515	serine threonine protein kinase
FNV58_38330	COG2340	Cysteine-rich secretory protein family
FNV58_38335	COG1254	Belongs to the acylphosphatase family
FNV58_38350	COG0477	Major facilitator Superfamily
FNV58_38390	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FNV58_38400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FNV58_38410	COG0442	prolyl-tRNA aminoacylation
FNV58_38420	COG0228	four-way junction DNA binding
FNV58_38425	COG1837	Belongs to the UPF0109 family
FNV58_38430	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FNV58_38435	COG0336	Belongs to the RNA methyltransferase TrmD family
FNV58_38440	COG0335	large ribosomal subunit rRNA binding
FNV58_38450	COG0681	Belongs to the peptidase S26 family
FNV58_38465	COG1051	belongs to the nudix hydrolase family
FNV58_38475	COG0792	nuclease activity
FNV58_38480	COG0606	chelatase, subunit chli
FNV58_38490	COG1191	sigma factor activity
FNV58_38505	COG0052	Belongs to the universal ribosomal protein uS2 family
FNV58_38510	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FNV58_38515	COG0528	UMP kinase activity
FNV58_38520	COG0233	cytoplasmic translational termination
FNV58_38525	COG0575	Belongs to the CDS family
FNV58_38540	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FNV58_38570	COG0531	amino acid
FNV58_38570	COG1674	ftsk spoiiie
FNV58_38605	COG2188	Transcriptional regulator
FNV58_38610	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FNV58_38660	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FNV58_38670	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FNV58_38675	COG3842	ATPase activity
FNV58_38705	COG1136	(ABC) transporter
FNV58_38710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNV58_38720	COG1012	belongs to the aldehyde dehydrogenase family
FNV58_38760	COG0477	Major facilitator Superfamily
FNV58_38785	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV58_38810	COG3842	ATPase activity
FNV58_38815	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNV58_38820	COG1177	transmembrane transport
FNV58_38825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV58_38855	COG2508	Transcriptional regulator
FNV58_38855	COG2508	Transcriptional regulator
FNV58_38860	COG1012	belongs to the aldehyde dehydrogenase family
FNV58_38870	COG1653	transport
FNV58_38875	COG4209	transmembrane transport
FNV58_38880	COG0395	ABC-type sugar transport system, permease component
FNV58_38920	COG5297	Belongs to the glycosyl hydrolase family 6
FNV58_38935	COG0653	protein targeting
FNV58_38945	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FNV58_38950	COG0750	zinc metalloprotease
FNV58_38955	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FNV58_38970	COG0442	prolyl-tRNA aminoacylation
FNV58_38990	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FNV58_39015	COG0779	Required for maturation of 30S ribosomal subunits
FNV58_39030	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FNV58_39040	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FNV58_39045	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FNV58_39070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNV58_39075	COG0601	transmembrane transport
FNV58_39085	COG0455	bacterial-type flagellum organization
FNV58_39105	COG1404	Belongs to the peptidase S8 family
FNV58_39180	COG1674	ftsk spoiiie
FNV58_39195	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FNV58_39200	COG1185	polyribonucleotide nucleotidyltransferase activity
FNV58_39205	COG0612	Peptidase, M16
FNV58_39210	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FNV58_39230	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FNV58_39235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV58_39240	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FNV58_39275	COG2208	phosphoserine phosphatase activity
FNV58_39275	COG2770	Histidine kinase
FNV58_39295	COG1674	ftsk spoiiie
FNV58_39305	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNV58_39315	COG1058	Belongs to the CinA family
FNV58_39315	COG1546	Belongs to the CinA family
FNV58_39320	COG1396	sequence-specific DNA binding
FNV58_39325	COG0783	Belongs to the Dps family
FNV58_39335	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_39340	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FNV58_39345	COG1201	RNA secondary structure unwinding
FNV58_39375	COG0628	permease
FNV58_39385	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FNV58_39405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FNV58_39415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV58_39420	COG0765	amino acid transport
FNV58_39425	COG0765	amino acid transport
FNV58_39430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNV58_39435	COG1126	abc transporter atp-binding protein
FNV58_39440	COG0745	RESPONSE REGULATOR receiver
FNV58_39445	COG2205	protein histidine kinase activity
FNV58_39475	COG2197	response regulator
FNV58_39505	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNV58_39515	COG3547	Transposase (IS116 IS110 IS902 family)
FNV58_39530	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FNV58_39540	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FNV58_39545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FNV58_39555	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FNV58_39595	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FNV58_39600	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FNV58_39605	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNV58_39620	COG0588	phosphoglycerate mutase activity
FNV58_39640	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FNV58_39675	COG1131	(ABC) transporter
FNV58_39680	COG1802	Transcriptional regulator
FNV58_39685	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FNV58_39700	COG0187	DNA topoisomerase II activity
FNV58_39715	COG2197	response regulator
FNV58_39725	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNV58_39730	COG4565	transcriptional regulatory protein
FNV58_39740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV58_39750	COG4565	transcriptional regulatory protein
FNV58_39755	COG3290	protein histidine kinase activity
FNV58_39770	COG0372	Belongs to the citrate synthase family
FNV58_39790	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FNV58_39795	COG0612	Peptidase, M16
FNV58_39805	COG0739	heme binding
FNV58_39810	COG1802	Transcriptional regulator
FNV58_39815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNV58_39825	COG0045	succinate-CoA ligase (ADP-forming) activity
FNV58_39825	COG1042	CoA-binding domain protein
FNV58_39825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNV58_39840	COG1435	thymidine kinase activity
FNV58_39885	COG0745	RESPONSE REGULATOR receiver
FNV58_39890	COG2205	protein histidine kinase activity
FNV58_39915	COG0756	dUTP diphosphatase activity
FNV58_39930	COG1136	(ABC) transporter
FNV58_39960	COG0569	domain protein
FNV58_39965	COG0531	amino acid
FNV58_39970	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FNV58_40030	COG4585	Histidine kinase
FNV58_40035	COG2409	Drug exporters of the RND superfamily
FNV58_40050	COG0243	molybdopterin cofactor binding
FNV58_40055	COG1799	cell septum assembly
FNV58_40085	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FNV58_40100	COG2235	arginine
FNV58_40105	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FNV58_40110	COG0531	amino acid
FNV58_40120	COG1024	Enoyl-CoA hydratase
FNV58_40165	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FNV58_40185	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FNV58_40195	COG1404	Belongs to the peptidase S8 family
FNV58_40205	COG0745	RESPONSE REGULATOR receiver
FNV58_40210	COG2205	protein histidine kinase activity
FNV58_40225	COG3537	Alpha-1,2-mannosidase
FNV58_40240	COG1175	transmembrane transport
FNV58_40250	COG1940	carbohydrate kinase activity
FNV58_40255	COG4213	ABC transporter substrate-binding protein
FNV58_40265	COG4214	carbohydrate transport
FNV58_40270	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FNV58_40275	COG0531	amino acid
FNV58_40310	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV58_40310	COG1024	Enoyl-CoA hydratase
FNV58_40315	COG0183	Belongs to the thiolase family
FNV58_40325	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FNV58_40340	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FNV58_40355	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNV58_40390	COG3220	belongs to the UPF0276 family
FNV58_40425	COG2326	polyphosphate kinase activity
FNV58_40430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FNV58_40470	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FNV58_40475	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNV58_40485	COG0515	serine threonine protein kinase
FNV58_40520	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
FNV58_40565	COG2205	protein histidine kinase activity
FNV58_40565	COG4999	Histidine kinase
FNV58_40565	COG3437	response regulator, receiver
FNV58_40565	COG3850	Histidine kinase
FNV58_40570	COG0745	RESPONSE REGULATOR receiver
FNV58_40570	COG3706	GGDEF domain
FNV58_40590	COG0154	amidase activity
FNV58_40605	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNV58_40630	COG0642	Histidine kinase
FNV58_40725	COG0504	CTP synthase activity
FNV58_40740	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FNV58_40865	COG0667	Aldo Keto reductase
FNV58_40885	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FNV58_40900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV58_40905	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FNV58_40930	COG0529	Catalyzes the synthesis of activated sulfate
FNV58_40935	COG0175	sulfate reduction
FNV58_40965	COG1960	acyl-CoA dehydrogenase activity
FNV58_40980	COG1917	Cupin 2, conserved barrel domain protein
FNV58_40980	COG4977	sequence-specific DNA binding
FNV58_41010	COG1609	Transcriptional regulator
FNV58_41040	COG0154	amidase activity
FNV58_41050	COG2040	homocysteine
FNV58_41105	COG2340	Cysteine-rich secretory protein family
FNV58_41110	COG0596	Alpha beta hydrolase
FNV58_41190	COG1131	(ABC) transporter
FNV58_41210	COG1175	transmembrane transport
FNV58_41225	COG0277	FAD linked oxidase domain protein
FNV58_41300	COG1162	GTPase activity
FNV58_41340	COG0028	Belongs to the TPP enzyme family
FNV58_41360	COG1802	Transcriptional regulator
FNV58_41390	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNV58_41395	COG2252	PERMEase
FNV58_41425	COG0726	polysaccharide deacetylase
FNV58_41430	COG0673	inositol 2-dehydrogenase activity
FNV58_41440	COG1132	(ABC) transporter
FNV58_41450	COG0596	Alpha beta hydrolase
FNV58_41455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV58_41475	COG1477	protein flavinylation
FNV58_41490	COG0745	RESPONSE REGULATOR receiver
FNV58_41495	COG2205	protein histidine kinase activity
FNV58_41515	COG3629	intracellular signal transduction
FNV58_41515	COG3903	Transcriptional regulator
FNV58_41525	COG3903	Transcriptional regulator
FNV58_41525	COG3629	intracellular signal transduction
FNV58_41540	COG4977	sequence-specific DNA binding
FNV58_41575	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FNV58_41590	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FNV58_41595	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FNV58_41670	COG0673	inositol 2-dehydrogenase activity
FNV58_41675	COG0667	Aldo Keto reductase
FNV58_41725	COG2267	carboxylic ester hydrolase activity
FNV58_41745	COG0598	Magnesium transport protein CorA
FNV58_41760	COG0583	DNA-binding transcription factor activity
FNV58_41780	COG2197	response regulator
FNV58_41785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNV58_41790	COG0318	PFAM AMP-dependent synthetase and ligase
FNV58_41800	COG3960	tartronate-semialdehyde synthase activity
FNV58_41810	COG0753	catalase activity
FNV58_41815	COG2084	Dehydrogenase
FNV58_41820	COG3622	Belongs to the hyi family
FNV58_41840	COG2351	hydroxyisourate hydrolase activity
FNV58_41855	COG2233	PERMEase
FNV58_41870	COG1733	regulation of RNA biosynthetic process
FNV58_41885	COG0406	alpha-ribazole phosphatase activity
FNV58_41890	COG0436	Aminotransferase
FNV58_41895	COG1733	regulation of RNA biosynthetic process
FNV58_41910	COG2304	oxidoreductase activity
FNV58_41915	COG4264	IucA IucC family
FNV58_41925	COG2815	serine threonine protein kinase
FNV58_41925	COG0515	serine threonine protein kinase
FNV58_41950	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FNV58_41960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV58_41975	COG1414	Transcriptional regulator
FNV58_41980	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FNV58_41985	COG4266	Belongs to the allantoicase family
FNV58_41990	COG0598	Magnesium transport protein CorA
FNV58_42005	COG0667	Aldo Keto reductase
FNV58_42010	COG2197	response regulator
FNV58_42020	COG0673	inositol 2-dehydrogenase activity
FNV58_42050	COG1940	carbohydrate kinase activity
FNV58_42060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FNV58_42105	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_42125	COG0640	Transcriptional regulator
FNV58_42210	COG0396	ATPase activity
FNV58_42225	COG0443	Heat shock 70 kDa protein
FNV58_42230	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FNV58_42235	COG0484	heat shock protein binding
FNV58_42245	COG0542	response to heat
FNV58_42260	COG3634	alkyl hydroperoxide reductase activity
FNV58_42285	COG2826	transposase and inactivated derivatives, IS30 family
FNV58_42520	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FNV58_42540	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNV58_42550	COG1621	beta-fructofuranosidase activity
FNV58_42555	COG1609	Transcriptional regulator
FNV58_42560	COG1653	transport
FNV58_42565	COG1175	transmembrane transport
FNV58_42570	COG0395	ABC-type sugar transport system, permease component
FNV58_42575	COG1621	beta-fructofuranosidase activity
FNV58_42585	COG2267	carboxylic ester hydrolase activity
FNV58_42600	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_42615	COG1511	domain protein
FNV58_42625	COG0321	lipoyl(octanoyl) transferase activity
FNV58_42650	COG2409	Drug exporters of the RND superfamily
FNV58_42660	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV58_42680	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_42725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV58_42765	COG4221	oxidoreductase activity
FNV58_42825	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV58_42830	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FNV58_42845	COG1126	abc transporter atp-binding protein
FNV58_42855	COG0765	amino acid transport
FNV58_42860	COG0765	amino acid transport
FNV58_42875	COG0405	Gamma-glutamyltransferase
FNV58_42915	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FNV58_42925	COG1953	Uracil, thiamine, allantoin
FNV58_42935	COG2226	methyltransferase
FNV58_42945	COG3851	Histidine kinase
FNV58_42950	COG2197	response regulator
FNV58_42965	COG0483	inositol monophosphate 1-phosphatase activity
FNV58_42980	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FNV58_42990	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNV58_42995	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FNV58_43005	COG1215	transferase activity, transferring glycosyl groups
FNV58_43015	COG4310	Domain of unknown function (DUF2172)
FNV58_43030	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FNV58_43040	COG0438	transferase activity, transferring glycosyl groups
FNV58_43065	COG0367	asparagine synthase
FNV58_43085	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FNV58_43095	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FNV58_43105	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_43110	COG0583	DNA-binding transcription factor activity
FNV58_43120	COG0477	Major facilitator Superfamily
FNV58_43135	COG1309	transcriptional regulator
FNV58_43190	COG1136	(ABC) transporter
FNV58_43200	COG2205	protein histidine kinase activity
FNV58_43205	COG2205	protein histidine kinase activity
FNV58_43215	COG0671	phosphoesterase, PA-phosphatase related
FNV58_43235	COG0640	Transcriptional regulator
FNV58_43255	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FNV58_43305	COG2130	NADP-dependent
FNV58_43310	COG0789	Transcriptional regulator
FNV58_43315	COG1192	Involved in chromosome partitioning
FNV58_43345	COG1929	Belongs to the glycerate kinase type-1 family
FNV58_43355	COG0688	phosphatidylethanolamine metabolic process
FNV58_43360	COG1960	acyl-CoA dehydrogenase activity
FNV58_43370	COG2301	Belongs to the HpcH HpaI aldolase family
FNV58_43390	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV58_43400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNV58_43400	COG0456	acetyltransferase
FNV58_43410	COG0596	Alpha beta hydrolase
FNV58_43435	COG2226	methyltransferase
FNV58_43475	COG2362	D-Aminopeptidase
FNV58_43480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNV58_43490	COG1619	proteins homologs of microcin C7 resistance protein MccF
FNV58_43520	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FNV58_43525	COG2226	methyltransferase
FNV58_43535	COG0488	(ABC) transporter
FNV58_43545	COG0693	protein deglycase activity
FNV58_43625	COG0443	Heat shock 70 kDa protein
FNV58_43640	COG2154	pterin-4-alpha-carbinolamine dehydratase
FNV58_43645	COG2226	methyltransferase
FNV58_43660	COG2378	regulation of single-species biofilm formation
FNV58_43665	COG3401	FG-GAP repeat protein
FNV58_43675	COG5297	Belongs to the glycosyl hydrolase family 6
FNV58_43675	COG4733	cellulase activity
FNV58_43680	COG5297	Belongs to the glycosyl hydrolase family 6
FNV58_43685	COG5297	Belongs to the glycosyl hydrolase family 6
FNV58_43705	COG4249	Peptidase C14 caspase catalytic subunit p20
FNV58_43705	COG2319	Wd-40 repeat
FNV58_43710	COG4221	oxidoreductase activity
FNV58_43720	COG0656	L-ascorbic acid biosynthetic process
FNV58_43745	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FNV58_43755	COG3469	chitinase activity
FNV58_43760	COG3250	beta-galactosidase activity
FNV58_43770	COG0477	Major facilitator Superfamily
FNV58_43805	COG1846	Transcriptional regulator
FNV58_43810	COG1335	isochorismatase
FNV58_43820	COG0583	DNA-binding transcription factor activity
FNV58_43825	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FNV58_43840	COG3383	formate dehydrogenase (NAD+) activity
FNV58_43845	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNV58_43855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNV58_43890	COG1940	carbohydrate kinase activity
FNV58_43895	COG1129	ABC transporter
FNV58_43900	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNV58_43905	COG1879	ABC-type sugar transport system periplasmic component
FNV58_43910	COG0673	inositol 2-dehydrogenase activity
FNV58_43920	COG3507	Belongs to the glycosyl hydrolase 43 family
FNV58_43950	COG0084	hydrolase, TatD family'
FNV58_43975	COG2223	nitrite transmembrane transporter activity
FNV58_43985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV58_43995	COG0045	succinate-CoA ligase (ADP-forming) activity
FNV58_44005	COG1012	belongs to the aldehyde dehydrogenase family
FNV58_44065	COG0789	Transcriptional regulator
FNV58_44105	COG0402	S-adenosylhomocysteine deaminase activity
FNV58_44135	COG2226	methyltransferase
FNV58_44155	COG4044	May play a role in the intracellular transport of hydrophobic ligands
FNV58_44165	COG4221	oxidoreductase activity
FNV58_44205	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FNV58_44210	COG0254	rRNA binding
FNV58_44225	COG4585	Histidine kinase
FNV58_44230	COG2197	response regulator
FNV58_44265	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV58_44270	COG2072	flavoprotein involved in K transport
FNV58_44290	COG0022	dehydrogenase e1 component
FNV58_44295	COG1309	transcriptional regulator
FNV58_44300	COG1960	acyl-CoA dehydrogenase activity
FNV58_44305	COG1063	alcohol dehydrogenase
FNV58_44320	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_44325	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_44330	COG0745	RESPONSE REGULATOR receiver
FNV58_44375	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_44385	COG0542	response to heat
FNV58_44415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV58_44425	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FNV58_44440	COG1063	alcohol dehydrogenase
FNV58_44450	COG0745	RESPONSE REGULATOR receiver
FNV58_44460	COG0477	Major facilitator Superfamily
FNV58_44465	COG2124	cytochrome p450
FNV58_44485	COG0477	Major facilitator Superfamily
FNV58_44535	COG0765	amino acid transport
FNV58_44565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV58_44570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV58_44585	COG0596	Alpha beta hydrolase
FNV58_44585	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV58_44595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FNV58_44620	COG0438	transferase activity, transferring glycosyl groups
FNV58_44640	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNV58_44670	COG0477	Major facilitator Superfamily
FNV58_44680	COG3467	pyridoxamine 5'-phosphate
FNV58_44695	COG0477	Major facilitator Superfamily
FNV58_44705	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FNV58_44725	COG0588	phosphoglycerate mutase activity
FNV58_44735	COG0166	Belongs to the GPI family
FNV58_44750	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FNV58_44785	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_44810	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FNV58_44815	COG3250	beta-galactosidase activity
FNV58_44820	COG0395	ABC-type sugar transport system, permease component
FNV58_44825	COG1175	transmembrane transport
FNV58_44835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV58_44840	COG1349	DNA-binding transcription factor activity
FNV58_44845	COG1486	melibiose metabolic process
FNV58_44855	COG3469	chitinase activity
FNV58_44920	COG3842	ATPase activity
FNV58_44925	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FNV58_44930	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNV58_44935	COG1177	transmembrane transport
FNV58_44955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNV58_44960	COG3938	Belongs to the proline racemase family
FNV58_44995	COG1175	transmembrane transport
FNV58_45000	COG0395	ABC-type sugar transport system, permease component
FNV58_45005	COG0366	Alpha amylase catalytic
FNV58_45015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV58_45020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV58_45125	COG3511	phospholipase C
FNV58_45200	COG0494	nUDIX hydrolase
FNV58_45290	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FNV58_45295	COG0477	Major facilitator Superfamily
FNV58_45310	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV58_45320	COG3485	protocatechuate 3,4-dioxygenase
FNV58_45325	COG3485	protocatechuate 3,4-dioxygenase
FNV58_45330	COG0183	Belongs to the thiolase family
FNV58_45345	COG1846	Transcriptional regulator
FNV58_45355	COG0714	Associated with various cellular activities
FNV58_45370	COG1793	dna ligase
FNV58_45450	COG1834	amidinotransferase
FNV58_45455	COG0488	(ABC) transporter
FNV58_45465	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FNV58_45485	COG1515	deoxyribonuclease V activity
FNV58_45490	COG3268	Saccharopine dehydrogenase
FNV58_45495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV58_45500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV58_45510	COG0183	Belongs to the thiolase family
FNV58_45515	COG1024	Enoyl-CoA hydratase
FNV58_45515	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV58_45520	COG0789	Transcriptional regulator
FNV58_45525	COG1113	amino acid transport
FNV58_45535	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FNV58_45545	COG2936	dipeptidyl-peptidase activity
FNV58_45560	COG0488	(ABC) transporter
FNV58_45570	COG2183	response to ionizing radiation
FNV58_45580	COG4977	sequence-specific DNA binding
FNV58_45590	COG1024	Enoyl-CoA hydratase
FNV58_45605	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FNV58_45610	COG4106	trans-aconitate 2-methyltransferase activity
FNV58_45610	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FNV58_45655	COG1134	teichoic acid transport
FNV58_45660	COG1562	ergosterol biosynthetic process
FNV58_45670	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FNV58_45680	COG1657	PFAM Prenyltransferase squalene oxidase
FNV58_45695	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FNV58_45700	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FNV58_45720	COG2365	Tyrosine phosphatase family
FNV58_45735	COG3401	FG-GAP repeat protein
FNV58_45745	COG2755	lipolytic protein G-D-S-L family
FNV58_45760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FNV58_45805	COG1063	alcohol dehydrogenase
FNV58_45810	COG0156	8-amino-7-oxononanoate synthase activity
FNV58_45815	COG0583	DNA-binding transcription factor activity
FNV58_45850	COG3958	Transketolase
FNV58_45855	COG3959	Transketolase, thiamine diphosphate binding domain
FNV58_45880	COG1132	(ABC) transporter
FNV58_45910	COG3033	Beta-eliminating lyase
FNV58_45930	COG1937	Protein conserved in bacteria
FNV58_45950	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FNV58_45970	COG3239	Fatty acid desaturase
FNV58_45980	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FNV58_46085	COG1454	alcohol dehydrogenase
FNV58_46095	COG0351	phosphomethylpyrimidine kinase
FNV58_46100	COG0702	epimerase
FNV58_46150	COG1595	DNA-templated transcription, initiation
FNV58_46160	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNV58_46175	COG1053	succinate dehydrogenase
FNV58_46180	COG1764	response to oxidative stress
FNV58_46185	COG1595	DNA-templated transcription, initiation
FNV58_46245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV58_46270	COG2838	Isocitrate dehydrogenase
FNV58_46275	COG0668	transmembrane transport
FNV58_46280	COG1024	Enoyl-CoA hydratase
FNV58_46295	COG2409	Drug exporters of the RND superfamily
FNV58_46300	COG1309	transcriptional regulator
FNV58_46305	COG0473	3-isopropylmalate dehydrogenase activity
FNV58_46315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV58_46330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNV58_46345	COG3483	tryptophan 2,3-dioxygenase activity
FNV58_46360	COG0475	glutathione-regulated potassium exporter activity
FNV58_46365	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FNV58_46380	COG2264	protein methyltransferase activity
FNV58_46410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNV58_46425	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNV58_46435	COG0697	spore germination
FNV58_46440	COG1509	lysine 2,3-aminomutase activity
FNV58_46450	COG0579	oxidoreductase
FNV58_46500	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FNV58_46520	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FNV58_46540	COG0297	glycogen (starch) synthase activity
FNV58_46545	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FNV58_46555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNV58_46565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV58_46570	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_46580	COG0701	Predicted permease
FNV58_46620	COG1175	transmembrane transport
FNV58_46625	COG0395	ABC-type sugar transport system, permease component
FNV58_46645	COG2186	Transcriptional regulator
FNV58_46655	COG1129	ABC transporter
FNV58_46660	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNV58_46665	COG4948	Mandelate Racemase Muconate Lactonizing
FNV58_46670	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_46705	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FNV58_46740	COG0726	polysaccharide deacetylase
FNV58_46790	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_46805	COG1053	succinate dehydrogenase
FNV58_46810	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FNV58_46830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV58_46845	COG0667	Aldo Keto reductase
FNV58_46880	COG1595	DNA-templated transcription, initiation
FNV58_46920	COG2814	Major facilitator Superfamily
FNV58_46925	COG0583	DNA-binding transcription factor activity
FNV58_46930	COG0583	DNA-binding transcription factor activity
FNV58_46945	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNV58_46950	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FNV58_46955	COG2080	2 iron, 2 sulfur cluster binding
FNV58_46970	COG0667	Aldo Keto reductase
FNV58_47000	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FNV58_47005	COG0121	glutamine amidotransferase
FNV58_47010	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FNV58_47015	COG3572	ergothioneine biosynthetic process
FNV58_47035	COG2268	Band 7 protein
FNV58_47050	COG1609	Transcriptional regulator
FNV58_47065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNV58_47075	COG0242	peptide deformylase activity
FNV58_47145	COG2186	Transcriptional regulator
FNV58_47155	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNV58_47170	COG1408	metallophosphoesterase
FNV58_47225	COG2378	regulation of single-species biofilm formation
FNV58_47250	COG1609	Transcriptional regulator
FNV58_47265	COG0395	ABC-type sugar transport system, permease component
FNV58_47315	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_47320	COG1309	transcriptional regulator
FNV58_47325	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_47360	COG0163	prenyltransferase activity
FNV58_47395	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FNV58_47415	COG2318	DinB family
FNV58_47435	COG1733	regulation of RNA biosynthetic process
FNV58_47445	COG2366	antibiotic biosynthetic process
FNV58_47450	COG1073	alpha beta
FNV58_47500	COG0583	DNA-binding transcription factor activity
FNV58_47505	COG2130	NADP-dependent
FNV58_47510	COG2186	Transcriptional regulator
FNV58_47530	COG2072	flavoprotein involved in K transport
FNV58_47535	COG0667	Aldo Keto reductase
FNV58_47540	COG1902	pentaerythritol trinitrate reductase activity
FNV58_47560	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_47575	COG0183	Belongs to the thiolase family
FNV58_47595	COG3485	protocatechuate 3,4-dioxygenase
FNV58_47605	COG2909	trisaccharide binding
FNV58_47630	COG0778	Nitroreductase
FNV58_47685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNV58_47705	COG3537	Alpha-1,2-mannosidase
FNV58_47720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV58_47740	COG0477	Major facilitator Superfamily
FNV58_47760	COG0006	proline dipeptidase activity
FNV58_47765	COG3291	Pkd domain containing protein
FNV58_47775	COG0673	inositol 2-dehydrogenase activity
FNV58_47790	COG1609	Transcriptional regulator
FNV58_47795	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNV58_47830	COG1122	ATPase activity
FNV58_47835	COG1122	ATPase activity
FNV58_47840	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FNV58_47865	COG0561	phosphatase activity
FNV58_47940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FNV58_47945	COG2151	metal-sulfur cluster biosynthetic enzyme
FNV58_47950	COG3396	Phenylacetate-CoA oxygenase
FNV58_47955	COG3460	Phenylacetate-CoA oxygenase
FNV58_47960	COG3396	Phenylacetate-CoA oxygenase
FNV58_47965	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNV58_47985	COG2050	protein possibly involved in aromatic compounds catabolism
FNV58_48000	COG0531	amino acid
FNV58_48070	COG2226	methyltransferase
FNV58_48095	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FNV58_48095	COG1024	Enoyl-CoA hydratase
FNV58_48105	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FNV58_48135	COG0375	protein maturation
FNV58_48140	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FNV58_48145	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FNV58_48150	COG0298	carbon dioxide binding
FNV58_48155	COG0409	Hydrogenase expression formation protein
FNV58_48160	COG0309	Hydrogenase expression formation protein (HypE)
FNV58_48190	COG1141	Ferredoxin
FNV58_48220	COG1136	(ABC) transporter
FNV58_48225	COG1174	glycine betaine transport
FNV58_48230	COG1174	glycine betaine transport
FNV58_48250	COG1125	glycine betaine transport
FNV58_48250	COG0517	IMP dehydrogenase activity
FNV58_48255	COG1556	Lactate utilization protein
FNV58_48260	COG1139	Iron-sulfur cluster binding protein
FNV58_48265	COG0247	lactate metabolic process
FNV58_48270	COG1070	Carbohydrate kinase
FNV58_48275	COG3347	Dehydrogenase
FNV58_48275	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_48285	COG1129	ABC transporter
FNV58_48320	COG1609	Transcriptional regulator
FNV58_48330	COG1595	DNA-templated transcription, initiation
FNV58_48335	COG1357	PFAM Pentapeptide repeats (8 copies)
FNV58_48345	COG1309	transcriptional regulator
FNV58_48355	COG2706	6-phosphogluconolactonase activity
FNV58_48380	COG0604	alcohol dehydrogenase
FNV58_48380	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_48380	COG3321	synthase
FNV58_48405	COG2723	6-phospho-beta-galactosidase activity
FNV58_48410	COG0395	ABC-type sugar transport system, permease component
FNV58_48415	COG1175	transmembrane transport
FNV58_48445	COG2267	carboxylic ester hydrolase activity
FNV58_48455	COG1796	DNA polymerase
FNV58_48455	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FNV58_48505	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNV58_48530	COG0515	serine threonine protein kinase
FNV58_48580	COG0640	Transcriptional regulator
FNV58_48590	COG0772	Belongs to the SEDS family
FNV58_48625	COG1316	TRANSCRIPTIONal
FNV58_48635	COG1278	Cold shock
FNV58_48670	COG0515	serine threonine protein kinase
FNV58_48680	COG1132	(ABC) transporter
FNV58_48685	COG1132	(ABC) transporter
FNV58_48690	COG2197	response regulator
FNV58_48695	COG0531	amino acid
FNV58_48805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV58_48805	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FNV58_48830	COG1609	Transcriptional regulator
FNV58_48855	COG1621	beta-fructofuranosidase activity
FNV58_48950	COG0789	Transcriptional regulator
FNV58_48965	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FNV58_49060	COG2318	DinB family
FNV58_49090	COG0745	RESPONSE REGULATOR receiver
FNV58_49150	COG2132	Multicopper oxidase
FNV58_49160	COG2226	methyltransferase
FNV58_49175	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FNV58_49195	COG1012	belongs to the aldehyde dehydrogenase family
FNV58_49235	COG0318	PFAM AMP-dependent synthetase and ligase
FNV58_49245	COG0531	amino acid
FNV58_49285	COG2124	cytochrome p450
FNV58_49325	COG0596	Alpha beta hydrolase
FNV58_49330	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FNV58_49330	COG1672	PFAM Archaeal ATPase
FNV58_49360	COG3250	beta-galactosidase activity
FNV58_49365	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNV58_49390	COG0640	Transcriptional regulator
FNV58_49425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNV58_49455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV58_49470	COG4209	transmembrane transport
FNV58_49475	COG0395	ABC-type sugar transport system, permease component
FNV58_49485	COG1609	Transcriptional regulator
FNV58_49500	COG0671	phosphoesterase, PA-phosphatase related
FNV58_49515	COG3832	glyoxalase III activity
FNV58_49560	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNV58_49560	COG2755	lipolytic protein G-D-S-L family
FNV58_49575	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FNV58_49625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNV58_49640	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FNV58_49655	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FNV58_49680	COG1132	(ABC) transporter
FNV58_49725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV58_49760	COG1846	Transcriptional regulator
FNV58_49760	COG1940	carbohydrate kinase activity
FNV58_49780	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FNV58_49805	COG1595	DNA-templated transcription, initiation
FNV58_49825	COG3866	Pectate lyase
FNV58_49850	COG4948	Mandelate Racemase Muconate Lactonizing
FNV58_49860	COG0583	DNA-binding transcription factor activity
FNV58_49910	COG1404	Belongs to the peptidase S8 family
FNV58_49930	COG2318	DinB family
FNV58_49965	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FNV58_49970	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNV58_49980	COG2409	Drug exporters of the RND superfamily
FNV58_50010	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_50015	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_50075	COG1802	Transcriptional regulator
FNV58_50135	COG0384	phenazine biosynthesis protein PhzF
FNV58_50145	COG0583	DNA-binding transcription factor activity
FNV58_50170	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_50220	COG1278	Cold shock
FNV58_50245	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FNV58_50250	COG0714	Associated with various cellular activities
FNV58_50290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV58_50315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FNV58_50330	COG1940	carbohydrate kinase activity
FNV58_50340	COG1175	transmembrane transport
FNV58_50345	COG0395	ABC-type sugar transport system, permease component
FNV58_50370	COG2340	Cysteine-rich secretory protein family
FNV58_50415	COG3469	chitinase activity
FNV58_50425	COG3548	integral membrane protein
FNV58_50435	COG0667	Aldo Keto reductase
FNV58_50450	COG3537	Alpha-1,2-mannosidase
FNV58_50475	COG1129	ABC transporter
FNV58_50485	COG1053	succinate dehydrogenase
FNV58_50495	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_50500	COG1960	acyl-CoA dehydrogenase activity
FNV58_50505	COG1024	Enoyl-CoA hydratase
FNV58_50515	COG0183	Belongs to the thiolase family
FNV58_50520	COG1960	acyl-CoA dehydrogenase activity
FNV58_50530	COG1960	acyl-CoA dehydrogenase activity
FNV58_50535	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_50540	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_50545	COG1024	Enoyl-CoA hydratase
FNV58_50575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV58_50590	COG1228	amidohydrolase
FNV58_50595	COG0515	serine threonine protein kinase
FNV58_50640	COG0730	response to heat
FNV58_50645	COG1937	Protein conserved in bacteria
FNV58_50685	COG1175	transmembrane transport
FNV58_50710	COG3345	alpha-galactosidase
FNV58_50720	COG0667	Aldo Keto reductase
FNV58_50725	COG1335	isochorismatase
FNV58_50745	COG3852	Histidine kinase
FNV58_50780	COG3290	protein histidine kinase activity
FNV58_50790	COG2814	Major facilitator Superfamily
FNV58_50815	COG1716	ATPase activity
FNV58_50815	COG1131	(ABC) transporter
FNV58_50815	COG0842	Transport permease protein
FNV58_50850	COG0739	heme binding
FNV58_50870	COG0583	DNA-binding transcription factor activity
FNV58_50875	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FNV58_50895	COG2197	response regulator
FNV58_50930	COG1335	isochorismatase
FNV58_50945	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FNV58_50965	COG5002	protein histidine kinase activity
FNV58_50975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNV58_50980	COG1053	succinate dehydrogenase
FNV58_50990	COG2318	DinB family
FNV58_51000	COG2318	DinB family
FNV58_51045	COG0596	Alpha beta hydrolase
FNV58_51050	COG1017	nitric oxide dioxygenase activity
FNV58_51050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FNV58_51075	COG1595	DNA-templated transcription, initiation
FNV58_51095	COG0745	RESPONSE REGULATOR receiver
FNV58_51125	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FNV58_51135	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNV58_51135	COG2080	2 iron, 2 sulfur cluster binding
FNV58_51160	COG2197	response regulator
FNV58_51185	COG4191	Histidine kinase
FNV58_51195	COG0517	IMP dehydrogenase activity
FNV58_51195	COG0516	GMP reductase activity
FNV58_51245	COG0589	response to stress
FNV58_51250	COG2326	polyphosphate kinase activity
FNV58_51255	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FNV58_51260	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FNV58_51280	COG1042	CoA-binding domain protein
FNV58_51280	COG0045	succinate-CoA ligase (ADP-forming) activity
FNV58_51280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNV58_51305	COG0517	IMP dehydrogenase activity
FNV58_51305	COG0516	GMP reductase activity
FNV58_51320	COG0574	Belongs to the PEP-utilizing enzyme family
FNV58_51320	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNV58_51360	COG0516	GMP reductase activity
FNV58_51360	COG0517	IMP dehydrogenase activity
FNV58_51380	COG2239	Acts as a magnesium transporter
FNV58_51440	COG1063	alcohol dehydrogenase
FNV58_51455	COG0531	amino acid
FNV58_51460	COG2235	arginine
FNV58_51465	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FNV58_51470	COG0549	Belongs to the carbamate kinase family
FNV58_51480	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FNV58_51510	COG1309	transcriptional regulator
FNV58_51515	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_51530	COG1278	Cold shock
FNV58_51535	COG0513	Belongs to the DEAD box helicase family
FNV58_51560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV58_51585	COG2274	protein secretion by the type I secretion system
FNV58_51630	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FNV58_51635	COG2226	methyltransferase
FNV58_51655	COG0789	Transcriptional regulator
FNV58_51685	COG1132	(ABC) transporter
FNV58_51695	COG2318	DinB family
FNV58_51715	COG1012	belongs to the aldehyde dehydrogenase family
FNV58_51720	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FNV58_51725	COG1414	Transcriptional regulator
FNV58_51740	COG4106	trans-aconitate 2-methyltransferase activity
FNV58_51770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV58_51775	COG1335	isochorismatase
FNV58_51805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNV58_51870	COG2208	phosphoserine phosphatase activity
FNV58_51885	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV58_51915	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_51920	COG0583	DNA-binding transcription factor activity
FNV58_51925	COG0243	molybdopterin cofactor binding
FNV58_51960	COG2837	iron assimilation
FNV58_51970	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_51985	COG2207	Transcriptional regulator
FNV58_51995	COG0745	RESPONSE REGULATOR receiver
FNV58_52000	COG2205	protein histidine kinase activity
FNV58_52100	COG1309	transcriptional regulator
FNV58_52115	COG1309	transcriptional regulator
FNV58_52120	COG1064	alcohol dehydrogenase
FNV58_52135	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNV58_52140	COG1129	ABC transporter
FNV58_52150	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_52205	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_52210	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_52240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNV58_52255	COG1522	sequence-specific DNA binding
FNV58_52305	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV58_52330	COG1595	DNA-templated transcription, initiation
FNV58_52360	COG2267	carboxylic ester hydrolase activity
FNV58_52375	COG0531	amino acid
FNV58_52385	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_52390	COG4221	oxidoreductase activity
FNV58_52415	COG4941	Belongs to the sigma-70 factor family
FNV58_52420	COG3795	YCII-related domain
FNV58_52465	COG1309	transcriptional regulator
FNV58_52470	COG0667	Aldo Keto reductase
FNV58_52500	COG2124	cytochrome p450
FNV58_52525	COG4585	Histidine kinase
FNV58_52530	COG2197	response regulator
FNV58_52560	COG2197	response regulator
FNV58_52565	COG4585	Histidine kinase
FNV58_52570	COG4552	Acetyltransferase involved in intracellular survival and related
FNV58_52610	COG0596	Alpha beta hydrolase
FNV58_52630	COG2197	response regulator
FNV58_52640	COG4221	oxidoreductase activity
FNV58_52645	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNV58_52645	COG1902	pentaerythritol trinitrate reductase activity
FNV58_52650	COG1012	belongs to the aldehyde dehydrogenase family
FNV58_52655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNV58_52665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNV58_52680	COG0583	DNA-binding transcription factor activity
FNV58_52685	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_52705	COG0745	RESPONSE REGULATOR receiver
FNV58_52805	COG1309	transcriptional regulator
FNV58_52815	COG1309	transcriptional regulator
FNV58_52855	COG3173	Aminoglycoside phosphotransferase
FNV58_52880	COG1012	belongs to the aldehyde dehydrogenase family
FNV58_52970	COG2409	Drug exporters of the RND superfamily
FNV58_52985	COG2072	flavoprotein involved in K transport
FNV58_52995	COG1012	belongs to the aldehyde dehydrogenase family
FNV58_53070	COG4977	sequence-specific DNA binding
FNV58_53090	COG1024	Enoyl-CoA hydratase
FNV58_53135	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNV58_53135	COG1902	pentaerythritol trinitrate reductase activity
FNV58_53155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FNV58_53160	COG4221	oxidoreductase activity
FNV58_53170	COG0477	Major facilitator Superfamily
FNV58_53185	COG0477	Major facilitator Superfamily
FNV58_53190	COG0477	Major facilitator Superfamily
FNV58_53210	COG1609	Transcriptional regulator
FNV58_53235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNV58_53240	COG0667	Aldo Keto reductase
FNV58_53275	COG0300	oxidoreductase activity
FNV58_53285	COG1309	transcriptional regulator
FNV58_53310	COG1802	Transcriptional regulator
FNV58_53315	COG2205	protein histidine kinase activity
FNV58_53320	COG0745	RESPONSE REGULATOR receiver
FNV58_53325	COG2409	Drug exporters of the RND superfamily
FNV58_53410	COG2261	transglycosylase associated protein
FNV58_53415	COG0640	Transcriptional regulator
FNV58_53425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNV58_53440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNV58_53495	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNV58_53510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNV58_53535	COG0202	RNA polymerase activity
FNV58_53635	COG4977	sequence-specific DNA binding
FNV58_53650	COG0477	Major facilitator Superfamily
FNV58_53690	COG4585	Histidine kinase
FNV58_53695	COG2197	response regulator
FNV58_53705	COG2272	Belongs to the type-B carboxylesterase lipase family
FNV58_53750	COG2208	phosphoserine phosphatase activity
FNV58_53750	COG2770	Histidine kinase
FNV58_53895	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNV58_53965	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_54035	COG4585	Histidine kinase
FNV58_54060	COG2135	peptidase activity
FNV58_54225	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FNV58_54270	COG3118	belongs to the thioredoxin family
FNV58_54320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNV58_54325	COG0483	inositol monophosphate 1-phosphatase activity
FNV58_54330	COG0583	DNA-binding transcription factor activity
FNV58_54355	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNV58_54380	COG0563	adenylate kinase activity
FNV58_54420	COG2159	amidohydrolase
FNV58_54445	COG2226	methyltransferase
FNV58_54490	COG2197	response regulator
FNV58_54530	COG3316	Transposase and inactivated derivatives
FNV58_54585	COG4584	PFAM Integrase catalytic
FNV58_54590	COG1484	DNA-dependent DNA replication
FNV58_54705	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNV58_54725	COG0300	oxidoreductase activity
FNV58_54725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV58_54725	COG3321	synthase
FNV58_54725	COG4221	oxidoreductase activity
FNV58_54745	COG0318	PFAM AMP-dependent synthetase and ligase
FNV58_54750	COG2197	response regulator
FNV58_54775	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FNV58_54780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNV58_54785	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_54790	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FNV58_54795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV58_54800	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FNV58_54805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV58_54810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNV58_54815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNV58_54825	COG0667	Aldo Keto reductase
FNV58_54840	COG1022	Amp-dependent synthetase and ligase
FNV58_54865	COG0477	Major facilitator Superfamily
FNV58_54870	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FNV58_54960	COG1335	isochorismatase
FNV58_54965	COG3619	membrane
FNV58_55005	COG3547	Transposase (IS116 IS110 IS902 family)
FNV58_55050	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FNV58_55070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FNV58_55130	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNV58_55135	COG3387	PFAM Glycoside hydrolase 15-related
FNV58_55140	COG3547	Transposase (IS116 IS110 IS902 family)
FNV58_55145	COG2197	response regulator
FNV58_55150	COG4585	Histidine kinase
FNV58_55180	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNV58_55185	COG1595	DNA-templated transcription, initiation
FNV58_55250	COG0248	Ppx GppA phosphatase
FNV58_55435	COG4977	sequence-specific DNA binding
FNV58_55500	COG2207	Transcriptional regulator
FNV58_55520	COG2801	Transposase and inactivated derivatives
FNV58_55525	COG2826	transposase and inactivated derivatives, IS30 family
FNV58_55620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FNV58_55665	COG1960	acyl-CoA dehydrogenase activity
FNV58_55670	COG1454	alcohol dehydrogenase
FNV58_55685	COG0583	DNA-binding transcription factor activity
FNV58_55690	COG0183	Belongs to the thiolase family
FNV58_55700	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FNV58_55715	COG0006	proline dipeptidase activity
FNV58_55720	COG2084	Dehydrogenase
FNV58_55750	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FNV58_55755	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNV58_55780	COG1609	Transcriptional regulator
FNV58_55805	COG1131	(ABC) transporter
FNV58_55815	COG0559	Belongs to the binding-protein-dependent transport system permease family
FNV58_55830	COG1335	isochorismatase
FNV58_55835	COG3619	membrane
FNV58_55870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNV58_55880	COG1116	anion transmembrane transporter activity
FNV58_55890	COG2353	YceI-like domain
FNV58_55895	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_55990	COG3328	transposase activity
FNV58_55995	COG3328	transposase activity
FNV58_56005	COG0069	glutamate synthase activity
FNV58_56070	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNV58_56075	COG1028	Short-chain dehydrogenase reductase Sdr
FNV58_56095	COG0477	Major facilitator Superfamily
FNV58_56100	COG1053	succinate dehydrogenase
FNV58_56105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNV58_56110	COG1024	Enoyl-CoA hydratase