STK_24925 bde82edac940a0fee5ba1657fc11b645 125 Gene3D G3DSA:3.30.460.10 2 106 7.7E-14 T 23-10-2018 STK_24925 bde82edac940a0fee5ba1657fc11b645 125 SUPERFAMILY SSF81301 17 96 5.84E-14 T 23-10-2018 STK_24925 bde82edac940a0fee5ba1657fc11b645 125 Pfam PF01909 Nucleotidyltransferase domain 15 76 1.8E-8 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_14270 4cf83f8de98e48cf80355c874485c0a8 143 Pfam PF10051 Uncharacterized protein conserved in archaea (DUF2286) 2 138 2.1E-53 T 23-10-2018 IPR017006 Uncharacterised conserved protein UCP032756 STK_14270 4cf83f8de98e48cf80355c874485c0a8 143 PIRSF PIRSF032756 1 143 3.3E-73 T 23-10-2018 IPR017006 Uncharacterised conserved protein UCP032756 STK_13840 2f568b83889872c5134c9f02e68a3257 359 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 136 7.1E-13 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 STK_13840 2f568b83889872c5134c9f02e68a3257 359 SUPERFAMILY SSF53092 2 134 5.58E-14 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal STK_13840 2f568b83889872c5134c9f02e68a3257 359 SUPERFAMILY SSF55920 114 352 4.97E-70 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like STK_13840 2f568b83889872c5134c9f02e68a3257 359 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 292 304 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site STK_13840 2f568b83889872c5134c9f02e68a3257 359 Pfam PF00557 Metallopeptidase family M24 143 346 8.3E-65 T 23-10-2018 IPR000994 Peptidase M24 STK_13840 2f568b83889872c5134c9f02e68a3257 359 Gene3D G3DSA:3.40.350.10 1 136 7.9E-17 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal STK_13840 2f568b83889872c5134c9f02e68a3257 359 Gene3D G3DSA:3.90.230.10 137 359 6.2E-77 T 23-10-2018 STK_24230 5ff41fb4f498f4be35fbe1194c3aa3b7 342 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 172 182 5.6E-18 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase STK_24230 5ff41fb4f498f4be35fbe1194c3aa3b7 342 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 238 250 5.6E-18 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase STK_24230 5ff41fb4f498f4be35fbe1194c3aa3b7 342 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 325 342 5.6E-18 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase STK_24230 5ff41fb4f498f4be35fbe1194c3aa3b7 342 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 143 157 5.6E-18 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase STK_24230 5ff41fb4f498f4be35fbe1194c3aa3b7 342 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 285 301 5.6E-18 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase STK_24230 5ff41fb4f498f4be35fbe1194c3aa3b7 342 Pfam PF01189 16S rRNA methyltransferase RsmB/F 162 340 1.5E-31 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 STK_24230 5ff41fb4f498f4be35fbe1194c3aa3b7 342 SUPERFAMILY SSF53335 94 339 7.05E-40 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_24230 5ff41fb4f498f4be35fbe1194c3aa3b7 342 Gene3D G3DSA:3.40.50.150 65 341 1.0E-55 T 23-10-2018 STK_03510 d8579eeb94f0c1352da21a937eac3efa 48 SMART SM00659 2 48 5.7E-20 T 23-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 STK_03510 d8579eeb94f0c1352da21a937eac3efa 48 Hamap MF_00615 DNA-directed RNA polymerase subunit P [rpoP]. 4 48 15.214 T 23-10-2018 IPR023464 DNA-directed RNA polymerase subunit P (Rpo12) GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_03510 d8579eeb94f0c1352da21a937eac3efa 48 SUPERFAMILY SSF63393 3 47 3.92E-12 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 STK_03510 d8579eeb94f0c1352da21a937eac3efa 48 Gene3D G3DSA:2.20.28.30 1 48 1.4E-21 T 23-10-2018 STK_13700 fa9a6497b9cb2c6fce0f759dd36588b1 247 SUPERFAMILY SSF52540 43 246 5.78E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_13700 fa9a6497b9cb2c6fce0f759dd36588b1 247 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 219 232 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 STK_13700 fa9a6497b9cb2c6fce0f759dd36588b1 247 SMART SM00382 50 245 4.6E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_13700 fa9a6497b9cb2c6fce0f759dd36588b1 247 SMART SM00962 51 246 3.0E-101 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 STK_13700 fa9a6497b9cb2c6fce0f759dd36588b1 247 Gene3D G3DSA:1.20.120.140 16 244 2.8E-83 T 23-10-2018 STK_13700 fa9a6497b9cb2c6fce0f759dd36588b1 247 Gene3D G3DSA:3.40.50.300 45 234 2.8E-83 T 23-10-2018 STK_13700 fa9a6497b9cb2c6fce0f759dd36588b1 247 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 1 245 4.6E-98 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 STK_13700 fa9a6497b9cb2c6fce0f759dd36588b1 247 Pfam PF00448 SRP54-type protein, GTPase domain 52 245 2.1E-73 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 STK_21330 d1093a3938afa90f019ffcccb345d6b2 332 SUPERFAMILY SSF51905 4 312 1.3E-46 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_21330 d1093a3938afa90f019ffcccb345d6b2 332 Gene3D G3DSA:3.50.50.60 125 243 4.6E-99 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_21330 d1093a3938afa90f019ffcccb345d6b2 332 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 297 2.3E-34 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 STK_21330 d1093a3938afa90f019ffcccb345d6b2 332 Hamap MF_01685 Ferredoxin--NADP reductase. 3 327 41.644 T 23-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 STK_21330 d1093a3938afa90f019ffcccb345d6b2 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 1.5E-23 T 23-10-2018 STK_21330 d1093a3938afa90f019ffcccb345d6b2 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.5E-23 T 23-10-2018 STK_21330 d1093a3938afa90f019ffcccb345d6b2 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 1.5E-23 T 23-10-2018 STK_21330 d1093a3938afa90f019ffcccb345d6b2 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 1.5E-23 T 23-10-2018 STK_21330 d1093a3938afa90f019ffcccb345d6b2 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 1.5E-23 T 23-10-2018 STK_21330 d1093a3938afa90f019ffcccb345d6b2 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 110 118 5.5E-25 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_21330 d1093a3938afa90f019ffcccb345d6b2 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 149 173 5.5E-25 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_21330 d1093a3938afa90f019ffcccb345d6b2 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 199 215 5.5E-25 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_21330 d1093a3938afa90f019ffcccb345d6b2 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 5.5E-25 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_21330 d1093a3938afa90f019ffcccb345d6b2 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 272 290 5.5E-25 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_21330 d1093a3938afa90f019ffcccb345d6b2 332 Gene3D G3DSA:3.50.50.60 5 306 4.6E-99 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_13640 d9b54a5351e2b403fb566fb0b4d6cb9a 904 TIGRFAM TIGR03683 A-tRNA_syn_arch: alanine--tRNA ligase 6 900 0.0 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 STK_13640 d9b54a5351e2b403fb566fb0b4d6cb9a 904 Gene3D G3DSA:3.30.980.10 595 736 5.2E-44 T 23-10-2018 STK_13640 d9b54a5351e2b403fb566fb0b4d6cb9a 904 SUPERFAMILY SSF55186 595 741 3.27E-41 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 STK_13640 d9b54a5351e2b403fb566fb0b4d6cb9a 904 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 694 737 8.2E-14 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 STK_13640 d9b54a5351e2b403fb566fb0b4d6cb9a 904 PRINTS PR00980 Alanyl-tRNA synthetase signature 328 344 5.9E-16 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 STK_13640 d9b54a5351e2b403fb566fb0b4d6cb9a 904 PRINTS PR00980 Alanyl-tRNA synthetase signature 211 222 5.9E-16 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 STK_13640 d9b54a5351e2b403fb566fb0b4d6cb9a 904 PRINTS PR00980 Alanyl-tRNA synthetase signature 131 142 5.9E-16 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 STK_13640 d9b54a5351e2b403fb566fb0b4d6cb9a 904 PRINTS PR00980 Alanyl-tRNA synthetase signature 352 365 5.9E-16 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 STK_13640 d9b54a5351e2b403fb566fb0b4d6cb9a 904 PRINTS PR00980 Alanyl-tRNA synthetase signature 237 250 5.9E-16 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 STK_13640 d9b54a5351e2b403fb566fb0b4d6cb9a 904 Gene3D G3DSA:3.30.930.10 2 252 1.4E-98 T 23-10-2018 STK_13640 d9b54a5351e2b403fb566fb0b4d6cb9a 904 Gene3D G3DSA:2.40.30.130 494 591 9.8E-31 T 23-10-2018 STK_13640 d9b54a5351e2b403fb566fb0b4d6cb9a 904 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 65 878 8.7E-199 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 STK_13640 d9b54a5351e2b403fb566fb0b4d6cb9a 904 SUPERFAMILY SSF55681 62 256 1.07E-56 T 23-10-2018 STK_13640 d9b54a5351e2b403fb566fb0b4d6cb9a 904 SUPERFAMILY SSF50447 503 591 5.65E-21 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily STK_13640 d9b54a5351e2b403fb566fb0b4d6cb9a 904 Hamap MF_00036_A Alanine--tRNA ligase [alaS]. 8 897 23.012 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 STK_13640 d9b54a5351e2b403fb566fb0b4d6cb9a 904 Pfam PF01411 tRNA synthetases class II (A) 65 595 8.9E-118 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 STK_13640 d9b54a5351e2b403fb566fb0b4d6cb9a 904 SMART SM00863 694 737 2.3E-17 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 STK_13640 d9b54a5351e2b403fb566fb0b4d6cb9a 904 Gene3D G3DSA:3.30.54.20 663 718 5.2E-44 T 23-10-2018 STK_13640 d9b54a5351e2b403fb566fb0b4d6cb9a 904 SUPERFAMILY SSF101353 299 507 1.28E-39 T 23-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 STK_04300 811b0f519502aef0474fb6e90f7edf06 248 SUPERFAMILY SSF75217 7 246 9.94E-34 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases STK_04300 811b0f519502aef0474fb6e90f7edf06 248 Gene3D G3DSA:3.40.1280.10 14 244 3.8E-36 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal STK_04300 811b0f519502aef0474fb6e90f7edf06 248 Gene3D G3DSA:2.40.50.140 100 153 3.8E-36 T 23-10-2018 STK_04300 811b0f519502aef0474fb6e90f7edf06 248 Pfam PF02598 Putative RNA methyltransferase 13 114 3.2E-12 T 23-10-2018 IPR003750 Putative RNA methyltransferase STK_16120 c1544af6c41734b83349ae48f5ccc08a 277 Gene3D G3DSA:1.10.10.10 1 51 1.6E-13 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_16120 c1544af6c41734b83349ae48f5ccc08a 277 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 3.0E-6 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_16120 c1544af6c41734b83349ae48f5ccc08a 277 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 3.0E-6 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_16120 c1544af6c41734b83349ae48f5ccc08a 277 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 3.0E-6 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_16120 c1544af6c41734b83349ae48f5ccc08a 277 SUPERFAMILY SSF46785 1 60 3.45E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_16120 c1544af6c41734b83349ae48f5ccc08a 277 SUPERFAMILY SSF46785 131 176 1.22E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_16120 c1544af6c41734b83349ae48f5ccc08a 277 Gene3D G3DSA:1.10.10.10 126 178 9.6E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_16120 c1544af6c41734b83349ae48f5ccc08a 277 Pfam PF13412 Winged helix-turn-helix DNA-binding 133 176 7.8E-9 T 23-10-2018 STK_16120 c1544af6c41734b83349ae48f5ccc08a 277 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 6.3E-13 T 23-10-2018 STK_16120 c1544af6c41734b83349ae48f5ccc08a 277 SMART SM00344 1 108 0.0047 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 STK_09520 39df4d49f97dda9c11d0bef8da09cb2c 413 Gene3D G3DSA:1.10.1410.30 6 253 9.5E-89 T 23-10-2018 STK_09520 39df4d49f97dda9c11d0bef8da09cb2c 413 Hamap MF_01264 CCA-adding enzyme [cca]. 1 413 147.428 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 STK_09520 39df4d49f97dda9c11d0bef8da09cb2c 413 SUPERFAMILY SSF81631 142 254 2.2E-39 T 23-10-2018 STK_09520 39df4d49f97dda9c11d0bef8da09cb2c 413 Gene3D G3DSA:3.30.70.590 259 389 1.0E-5 T 23-10-2018 STK_09520 39df4d49f97dda9c11d0bef8da09cb2c 413 SUPERFAMILY SSF81301 4 138 1.42E-35 T 23-10-2018 STK_09520 39df4d49f97dda9c11d0bef8da09cb2c 413 PIRSF PIRSF005335 1 413 3.4E-149 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 STK_09520 39df4d49f97dda9c11d0bef8da09cb2c 413 Gene3D G3DSA:3.30.460.10 13 140 9.5E-89 T 23-10-2018 STK_09520 39df4d49f97dda9c11d0bef8da09cb2c 413 Pfam PF01909 Nucleotidyltransferase domain 26 129 1.8E-14 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_09520 39df4d49f97dda9c11d0bef8da09cb2c 413 SUPERFAMILY SSF55003 239 412 1.88E-41 T 23-10-2018 IPR011068 Nucleotidyltransferase, class I-like, C-terminal GO:0003723|GO:0016779|GO:0031123 STK_09520 39df4d49f97dda9c11d0bef8da09cb2c 413 Pfam PF09249 tRNA nucleotidyltransferase, second domain 144 253 1.5E-43 T 23-10-2018 IPR015329 tRNA nucleotidyltransferase, substrate binding GO:0004810|GO:0016437 STK_09520 39df4d49f97dda9c11d0bef8da09cb2c 413 TIGRFAM TIGR03671 cca_archaeal: CCA-adding enzyme 3 384 1.7E-136 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 STK_07350 965dc9b6c337a6c29219befd7d604934 419 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 249 286 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 STK_07350 965dc9b6c337a6c29219befd7d604934 419 PIRSF PIRSF000521 15 130 1.2E-8 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 STK_07350 965dc9b6c337a6c29219befd7d604934 419 PIRSF PIRSF000521 124 418 2.8E-44 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 STK_07350 965dc9b6c337a6c29219befd7d604934 419 Gene3D G3DSA:3.40.640.10 62 331 1.2E-163 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 STK_07350 965dc9b6c337a6c29219befd7d604934 419 SUPERFAMILY SSF53383 21 416 1.55E-114 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase STK_07350 965dc9b6c337a6c29219befd7d604934 419 Pfam PF00202 Aminotransferase class-III 21 415 5.6E-106 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 STK_07350 965dc9b6c337a6c29219befd7d604934 419 Gene3D G3DSA:3.90.1150.10 25 413 1.2E-163 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 STK_01260 369c8b7c5560b79d8735b07456941a49 377 Pfam PF13186 Iron-sulfur cluster-binding domain 285 342 1.1E-8 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain STK_01260 369c8b7c5560b79d8735b07456941a49 377 SUPERFAMILY SSF102114 36 351 8.5E-75 T 23-10-2018 STK_01260 369c8b7c5560b79d8735b07456941a49 377 Pfam PF04055 Radical SAM superfamily 42 179 2.3E-23 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_01260 369c8b7c5560b79d8735b07456941a49 377 Pfam PF13353 4Fe-4S single cluster domain 43 128 3.6E-8 T 23-10-2018 STK_01260 369c8b7c5560b79d8735b07456941a49 377 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 285 370 1.2E-13 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain STK_01260 369c8b7c5560b79d8735b07456941a49 377 Gene3D G3DSA:3.20.20.70 36 375 3.2E-63 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_01260 369c8b7c5560b79d8735b07456941a49 377 SMART SM00729 36 235 1.6E-5 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 STK_01260 369c8b7c5560b79d8735b07456941a49 377 PIRSF PIRSF037420 20 377 9.0E-133 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E STK_01760 b34545f64d5f851c7c408784f879dcb3 188 Hamap MF_00039 Putative adenylate kinase. 1 164 24.692 T 23-10-2018 IPR020618 Adenylate kinase isoenzyme 6 GO:0004017|GO:0005524 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 STK_01760 b34545f64d5f851c7c408784f879dcb3 188 Gene3D G3DSA:3.40.50.300 1 176 1.5E-39 T 23-10-2018 STK_01760 b34545f64d5f851c7c408784f879dcb3 188 Pfam PF13238 AAA domain 3 120 1.3E-19 T 23-10-2018 STK_01760 b34545f64d5f851c7c408784f879dcb3 188 SUPERFAMILY SSF52540 1 153 3.68E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_14610 950c325364159a89c5a063f86519b26e 194 SUPERFAMILY SSF54211 5 88 1.9E-25 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold STK_14610 950c325364159a89c5a063f86519b26e 194 Gene3D G3DSA:3.30.230.40 92 194 1.4E-27 T 23-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 STK_14610 950c325364159a89c5a063f86519b26e 194 Gene3D G3DSA:3.30.230.40 1 91 1.1E-27 T 23-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 STK_14610 950c325364159a89c5a063f86519b26e 194 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 33 176 4.8E-48 T 23-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 STK_14610 950c325364159a89c5a063f86519b26e 194 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 4 194 33.709 T 23-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 STK_14610 950c325364159a89c5a063f86519b26e 194 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 158 170 - T 23-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 STK_14610 950c325364159a89c5a063f86519b26e 194 SUPERFAMILY SSF54211 89 181 1.14E-28 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold STK_23440 18ab011279fd149d3191810c251768bc 458 Gene3D G3DSA:3.40.50.880 233 416 2.7E-19 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_23440 18ab011279fd149d3191810c251768bc 458 SUPERFAMILY SSF52317 176 366 3.4E-30 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_23440 18ab011279fd149d3191810c251768bc 458 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 214 5.2E-11 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain STK_23440 18ab011279fd149d3191810c251768bc 458 Gene3D G3DSA:3.40.50.300 2 226 1.4E-33 T 23-10-2018 STK_23440 18ab011279fd149d3191810c251768bc 458 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 458 100.023 T 23-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 STK_23440 18ab011279fd149d3191810c251768bc 458 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 3 411 4.6E-96 T 23-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 STK_23440 18ab011279fd149d3191810c251768bc 458 SUPERFAMILY SSF52540 2 222 1.25E-29 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_23440 18ab011279fd149d3191810c251768bc 458 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 234 409 8.0E-35 T 23-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 STK_12820 0197589ba642b2d859b1e1786fdc39c3 358 SUPERFAMILY SSF102114 69 291 5.36E-15 T 23-10-2018 STK_12820 0197589ba642b2d859b1e1786fdc39c3 358 Gene3D G3DSA:3.20.20.70 10 324 5.7E-112 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_12820 0197589ba642b2d859b1e1786fdc39c3 358 Hamap MF_01921 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase [taw1]. 13 316 48.019 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 STK_12820 0197589ba642b2d859b1e1786fdc39c3 358 Pfam PF04055 Radical SAM superfamily 66 249 1.8E-21 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_12820 0197589ba642b2d859b1e1786fdc39c3 358 Pfam PF08608 Wyosine base formation 256 316 8.6E-23 T 23-10-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 STK_12820 0197589ba642b2d859b1e1786fdc39c3 358 TIGRFAM TIGR03972 rSAM_TYW1: wyosine biosynthesis protein TYW1 14 315 2.1E-130 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 STK_25220 eb0a671456082e00f791a0b221d63b6b 234 SUPERFAMILY SSF52540 4 227 3.52E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_25220 eb0a671456082e00f791a0b221d63b6b 234 SMART SM00382 24 186 5.3E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_25220 eb0a671456082e00f791a0b221d63b6b 234 Pfam PF06745 KaiC 8 228 2.5E-15 T 23-10-2018 IPR014774 KaiC-like domain STK_25220 eb0a671456082e00f791a0b221d63b6b 234 Gene3D G3DSA:3.40.50.300 6 234 2.9E-49 T 23-10-2018 STK_10870 7cf9202155755c41268127cfd69a7e06 271 SUPERFAMILY SSF103481 170 268 6.28E-12 T 23-10-2018 STK_10870 7cf9202155755c41268127cfd69a7e06 271 Pfam PF00892 EamA-like transporter family 136 266 1.2E-20 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 STK_10870 7cf9202155755c41268127cfd69a7e06 271 Pfam PF00892 EamA-like transporter family 8 124 3.2E-13 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 STK_10870 7cf9202155755c41268127cfd69a7e06 271 SUPERFAMILY SSF103481 58 127 1.7E-10 T 23-10-2018 STK_25770 d8372938a1919af3a3ef5c0da2fa18dd 347 Gene3D G3DSA:3.40.50.720 163 299 1.1E-132 T 23-10-2018 STK_25770 d8372938a1919af3a3ef5c0da2fa18dd 347 SUPERFAMILY SSF50129 1 178 1.1E-52 T 23-10-2018 IPR011032 GroES-like superfamily STK_25770 d8372938a1919af3a3ef5c0da2fa18dd 347 SMART SM00829 10 345 6.8E-8 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 STK_25770 d8372938a1919af3a3ef5c0da2fa18dd 347 SUPERFAMILY SSF51735 144 315 6.53E-40 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_25770 d8372938a1919af3a3ef5c0da2fa18dd 347 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 67 81 - T 23-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 STK_25770 d8372938a1919af3a3ef5c0da2fa18dd 347 Pfam PF00107 Zinc-binding dehydrogenase 182 308 1.0E-29 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 STK_25770 d8372938a1919af3a3ef5c0da2fa18dd 347 Gene3D G3DSA:3.90.180.10 13 332 1.1E-132 T 23-10-2018 STK_25770 d8372938a1919af3a3ef5c0da2fa18dd 347 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 139 2.4E-34 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 STK_15670 3d3b1ec189eb24dbb2dc8b146bafc995 449 Gene3D G3DSA:3.40.50.1100 33 254 8.3E-161 T 23-10-2018 STK_15670 3d3b1ec189eb24dbb2dc8b146bafc995 449 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 40 444 38.899 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 STK_15670 3d3b1ec189eb24dbb2dc8b146bafc995 449 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 92 431 9.1E-36 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme STK_15670 3d3b1ec189eb24dbb2dc8b146bafc995 449 SUPERFAMILY SSF53686 63 443 1.33E-94 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme STK_15670 3d3b1ec189eb24dbb2dc8b146bafc995 449 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 32 445 7.2E-200 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 STK_15670 3d3b1ec189eb24dbb2dc8b146bafc995 449 PIRSF PIRSF001413 28 449 3.5E-156 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 STK_15670 3d3b1ec189eb24dbb2dc8b146bafc995 449 PIRSF PIRSF500824 20 449 4.0E-200 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 STK_15670 3d3b1ec189eb24dbb2dc8b146bafc995 449 Gene3D G3DSA:3.40.50.1100 32 437 8.3E-161 T 23-10-2018 STK_15670 3d3b1ec189eb24dbb2dc8b146bafc995 449 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 122 136 - T 23-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 STK_04140 cc3aa49d9933edf418eb8ec9237e5023 214 Pfam PF00333 Ribosomal protein S5, N-terminal domain 54 118 1.8E-22 T 23-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 STK_04140 cc3aa49d9933edf418eb8ec9237e5023 214 Gene3D G3DSA:3.30.230.10 117 212 1.1E-33 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup STK_04140 cc3aa49d9933edf418eb8ec9237e5023 214 Pfam PF03719 Ribosomal protein S5, C-terminal domain 140 204 1.1E-19 T 23-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 STK_04140 cc3aa49d9933edf418eb8ec9237e5023 214 SUPERFAMILY SSF54768 48 119 5.23E-18 T 23-10-2018 STK_04140 cc3aa49d9933edf418eb8ec9237e5023 214 Gene3D G3DSA:3.30.160.770 12 116 5.9E-38 T 23-10-2018 STK_04140 cc3aa49d9933edf418eb8ec9237e5023 214 SUPERFAMILY SSF54211 132 210 7.08E-21 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold STK_04140 cc3aa49d9933edf418eb8ec9237e5023 214 Hamap MF_01307_A 30S ribosomal protein S5 [rpsE]. 6 206 45.827 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04140 cc3aa49d9933edf418eb8ec9237e5023 214 ProSitePatterns PS00585 Ribosomal protein S5 signature. 71 103 - T 23-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site STK_04140 cc3aa49d9933edf418eb8ec9237e5023 214 TIGRFAM TIGR01020 uS5_euk_arch: ribosomal protein uS5 9 213 2.2E-93 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_05930 34fd48eac6b04ad121c1288b63defe33 513 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 155 169 - T 23-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 STK_05930 34fd48eac6b04ad121c1288b63defe33 513 Pfam PF00289 Biotin carboxylase, N-terminal domain 4 112 1.2E-44 T 23-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 STK_05930 34fd48eac6b04ad121c1288b63defe33 513 SUPERFAMILY SSF52440 2 114 1.22E-49 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily STK_05930 34fd48eac6b04ad121c1288b63defe33 513 SUPERFAMILY SSF51246 336 452 2.09E-38 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 STK_05930 34fd48eac6b04ad121c1288b63defe33 513 Gene3D G3DSA:3.30.470.130 1 455 5.6E-172 T 23-10-2018 STK_05930 34fd48eac6b04ad121c1288b63defe33 513 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 122 325 3.0E-63 T 23-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 STK_05930 34fd48eac6b04ad121c1288b63defe33 513 SMART SM00878 341 447 1.6E-50 T 23-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 STK_05930 34fd48eac6b04ad121c1288b63defe33 513 SUPERFAMILY SSF56059 85 354 7.42E-56 T 23-10-2018 STK_05930 34fd48eac6b04ad121c1288b63defe33 513 Pfam PF02785 Biotin carboxylase C-terminal domain 341 447 2.1E-34 T 23-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 STK_21030 19541834a2400204247cc13683e780f5 499 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 215 481 3.8E-73 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 STK_21030 19541834a2400204247cc13683e780f5 499 Gene3D G3DSA:3.40.50.10260 1 205 2.1E-55 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 STK_21030 19541834a2400204247cc13683e780f5 499 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 208 486 23.349 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 STK_21030 19541834a2400204247cc13683e780f5 499 Pfam PF03853 YjeF-related protein N-terminus 24 184 1.0E-40 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 STK_21030 19541834a2400204247cc13683e780f5 499 SUPERFAMILY SSF64153 2 230 5.1E-57 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 STK_21030 19541834a2400204247cc13683e780f5 499 PIRSF PIRSF017184 1 487 1.6E-103 T 23-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 STK_21030 19541834a2400204247cc13683e780f5 499 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 2 200 22.787 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 STK_21030 19541834a2400204247cc13683e780f5 499 Pfam PF01256 Carbohydrate kinase 231 478 2.4E-53 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 STK_21030 19541834a2400204247cc13683e780f5 499 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 3 201 2.5E-55 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 STK_21030 19541834a2400204247cc13683e780f5 499 Gene3D G3DSA:3.40.1190.20 211 484 3.8E-82 T 23-10-2018 IPR029056 Ribokinase-like STK_21030 19541834a2400204247cc13683e780f5 499 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 422 432 - T 23-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site STK_21030 19541834a2400204247cc13683e780f5 499 SUPERFAMILY SSF53613 209 483 7.86E-70 T 23-10-2018 IPR029056 Ribokinase-like STK_21710 4c4f56836b9d95d2bdd445789c7f2b3b 359 PIRSF PIRSF000148 7 357 7.3E-83 T 23-10-2018 STK_21710 4c4f56836b9d95d2bdd445789c7f2b3b 359 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 9 132 1.5E-31 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 STK_21710 4c4f56836b9d95d2bdd445789c7f2b3b 359 SUPERFAMILY SSF51735 8 180 9.43E-37 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_21710 4c4f56836b9d95d2bdd445789c7f2b3b 359 Gene3D G3DSA:3.30.360.10 153 335 1.8E-135 T 23-10-2018 STK_21710 4c4f56836b9d95d2bdd445789c7f2b3b 359 SMART SM00859 9 134 1.4E-34 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 STK_21710 4c4f56836b9d95d2bdd445789c7f2b3b 359 TIGRFAM TIGR00978 asd_EA: aspartate-semialdehyde dehydrogenase 8 352 1.9E-104 T 23-10-2018 IPR005676 Aspartate-semialdehyde dehydrogenase, peptidoglycan lacking GO:0050661|GO:0055114 STK_21710 4c4f56836b9d95d2bdd445789c7f2b3b 359 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 162 337 3.0E-20 T 23-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 STK_21710 4c4f56836b9d95d2bdd445789c7f2b3b 359 SUPERFAMILY SSF55347 151 339 1.04E-35 T 23-10-2018 STK_21710 4c4f56836b9d95d2bdd445789c7f2b3b 359 Gene3D G3DSA:3.40.50.720 9 355 1.8E-135 T 23-10-2018 STK_14440 7df6a0e6217c2d2bf942482d2ab843c2 144 Pfam PF01870 Archaeal holliday junction resolvase (hjc) 11 101 3.7E-28 T 23-10-2018 IPR002732 Holliday junction resolvase Hjc STK_14440 7df6a0e6217c2d2bf942482d2ab843c2 144 ProDom PD015874 RESOLVASE HOLLIDAY JUNCTION ARCHAEAL HOLLIDAY-JUNCTION TYPE MJ0497 ORF-C21_024 PF1503 NEQ424 12 141 5.0E-69 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal STK_14440 7df6a0e6217c2d2bf942482d2ab843c2 144 PIRSF PIRSF004985 2 140 6.3E-50 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal STK_14440 7df6a0e6217c2d2bf942482d2ab843c2 144 Gene3D G3DSA:3.40.1350.10 1 144 3.6E-59 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 STK_14440 7df6a0e6217c2d2bf942482d2ab843c2 144 Hamap MF_01490 Holliday junction resolvase Hjc [hjc]. 4 140 35.813 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal STK_14440 7df6a0e6217c2d2bf942482d2ab843c2 144 SUPERFAMILY SSF52980 10 140 2.9E-32 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 STK_03785 0285f330e93c687363d20e22ce4cdaf9 67 SMART SM01389 8 67 2.6E-24 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 STK_03785 0285f330e93c687363d20e22ce4cdaf9 67 Pfam PF06093 Spt4/RpoE2 zinc finger 9 67 3.7E-14 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 STK_03785 0285f330e93c687363d20e22ce4cdaf9 67 Gene3D G3DSA:2.20.28.90 2 67 8.2E-23 T 23-10-2018 IPR038589 Archaeal transcription elongation factor Spt4 superfamily STK_03785 0285f330e93c687363d20e22ce4cdaf9 67 SUPERFAMILY SSF63393 3 66 5.23E-19 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 STK_03785 0285f330e93c687363d20e22ce4cdaf9 67 ProDom PD019197 RNA DNA-DIRECTED POLYMERASE SUBUNIT E'' POLYMERASE RPOE2 TRANSFERASE NUCLEOTIDYLTRANSFERASE E 19 66 1.0E-21 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 STK_03785 0285f330e93c687363d20e22ce4cdaf9 67 Hamap MF_00949 Transcription elongation factor Spt4 [spt4]. 10 67 28.145 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 STK_18430 44acfe4a8ffb309ee4e292554a3d8d06 233 SUPERFAMILY SSF46785 28 107 6.02E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_18430 44acfe4a8ffb309ee4e292554a3d8d06 233 Pfam PF13412 Winged helix-turn-helix DNA-binding 54 79 2.6E-5 T 23-10-2018 STK_18430 44acfe4a8ffb309ee4e292554a3d8d06 233 Gene3D G3DSA:1.10.10.10 29 104 2.1E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_24120 ea35046a8e369e12dcfd2a5a831a5341 338 TIGRFAM TIGR03961 rSAM_PTO1314: archaeal radical SAM protein, PTO1314 family 4 337 6.9E-197 T 23-10-2018 IPR023863 Archaeal radical SAM protein, PTO1314 family STK_24120 ea35046a8e369e12dcfd2a5a831a5341 338 Gene3D G3DSA:3.20.20.70 31 293 7.2E-48 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_24120 ea35046a8e369e12dcfd2a5a831a5341 338 Pfam PF11946 Domain of unknown function (DUF3463) 189 324 4.3E-28 T 23-10-2018 IPR022563 Domain of unknown function DUF3463 STK_24120 ea35046a8e369e12dcfd2a5a831a5341 338 Pfam PF04055 Radical SAM superfamily 35 181 1.8E-19 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_24120 ea35046a8e369e12dcfd2a5a831a5341 338 Pfam PF13353 4Fe-4S single cluster domain 33 130 2.1E-7 T 23-10-2018 STK_24120 ea35046a8e369e12dcfd2a5a831a5341 338 SUPERFAMILY SSF102114 31 305 1.44E-52 T 23-10-2018 STK_12780 a17aa65e9d335ea8e1798600e4651a7b 254 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 221 2.2E-23 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 STK_12780 a17aa65e9d335ea8e1798600e4651a7b 254 Gene3D G3DSA:3.40.1010.10 1 113 2.2E-29 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 STK_12780 a17aa65e9d335ea8e1798600e4651a7b 254 Hamap MF_01084 Diphthine synthase [dphB]. 3 254 30.477 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 STK_12780 a17aa65e9d335ea8e1798600e4651a7b 254 TIGRFAM TIGR00522 dph5: diphthine synthase 4 252 2.1E-54 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 STK_12780 a17aa65e9d335ea8e1798600e4651a7b 254 PIRSF PIRSF036432 3 254 1.2E-86 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 STK_12780 a17aa65e9d335ea8e1798600e4651a7b 254 Gene3D G3DSA:3.30.950.10 114 254 2.3E-36 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 STK_12780 a17aa65e9d335ea8e1798600e4651a7b 254 SUPERFAMILY SSF53790 3 250 3.93E-49 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 STK_25490 5e499f5f2c9e3137307ef0922a9c4e63 374 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 4 359 8.1E-116 T 23-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase STK_25490 5e499f5f2c9e3137307ef0922a9c4e63 374 Gene3D G3DSA:3.30.70.360 180 287 9.1E-67 T 23-10-2018 STK_25490 5e499f5f2c9e3137307ef0922a9c4e63 374 SUPERFAMILY SSF55031 180 288 2.88E-10 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain STK_25490 5e499f5f2c9e3137307ef0922a9c4e63 374 Pfam PF01546 Peptidase family M20/M25/M40 81 365 4.0E-33 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 STK_25490 5e499f5f2c9e3137307ef0922a9c4e63 374 Pfam PF07687 Peptidase dimerisation domain 176 271 4.6E-13 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain STK_25490 5e499f5f2c9e3137307ef0922a9c4e63 374 SUPERFAMILY SSF53187 4 366 2.0E-48 T 23-10-2018 STK_25490 5e499f5f2c9e3137307ef0922a9c4e63 374 Gene3D G3DSA:3.40.630.10 6 356 9.1E-67 T 23-10-2018 STK_08305 186d4dd05c8116a5993984df09310c13 57 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 6 48 6.8E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_08305 186d4dd05c8116a5993984df09310c13 57 SMART SM00966 7 54 8.2E-10 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_08305 186d4dd05c8116a5993984df09310c13 57 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 50 1.1E-9 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_08305 186d4dd05c8116a5993984df09310c13 57 Gene3D G3DSA:2.10.260.10 1 47 2.0E-17 T 23-10-2018 STK_08305 186d4dd05c8116a5993984df09310c13 57 SUPERFAMILY SSF89447 5 44 1.53E-9 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily STK_19690 efe24f8ba5b991f52d8bba9988bf6baa 176 SUPERFAMILY SSF51182 11 173 3.43E-60 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily STK_19690 efe24f8ba5b991f52d8bba9988bf6baa 176 Gene3D G3DSA:2.60.120.10 1 176 8.4E-69 T 23-10-2018 IPR014710 RmlC-like jelly roll fold STK_19690 efe24f8ba5b991f52d8bba9988bf6baa 176 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 11 170 4.4E-58 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 STK_19690 efe24f8ba5b991f52d8bba9988bf6baa 176 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 11 172 5.0E-58 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 STK_19690 efe24f8ba5b991f52d8bba9988bf6baa 176 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 11 175 1.0E-93 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 STK_21450 5c44852c3bed218cb2af02c266089678 219 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 97 186 4.5E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 STK_21450 5c44852c3bed218cb2af02c266089678 219 Gene3D G3DSA:1.10.150.660 16 94 6.9E-72 T 23-10-2018 STK_21450 5c44852c3bed218cb2af02c266089678 219 SUPERFAMILY SSF56784 1 216 5.83E-33 T 23-10-2018 IPR036412 HAD-like superfamily STK_21450 5c44852c3bed218cb2af02c266089678 219 Pfam PF00702 haloacid dehalogenase-like hydrolase 68 186 7.4E-13 T 23-10-2018 STK_21450 5c44852c3bed218cb2af02c266089678 219 Gene3D G3DSA:3.40.50.1000 5 213 6.9E-72 T 23-10-2018 IPR023214 HAD superfamily STK_03650 6d5349df3e174f2eeb4eda1aa483d68a 189 Hamap MF_01405 dITP/XTP pyrophosphatase. 5 186 38.367 T 23-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 STK_03650 6d5349df3e174f2eeb4eda1aa483d68a 189 Pfam PF01725 Ham1 family 8 182 9.8E-48 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 STK_03650 6d5349df3e174f2eeb4eda1aa483d68a 189 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 7 184 5.8E-59 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 STK_03650 6d5349df3e174f2eeb4eda1aa483d68a 189 Gene3D G3DSA:3.90.950.10 1 187 8.2E-61 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like STK_03650 6d5349df3e174f2eeb4eda1aa483d68a 189 SUPERFAMILY SSF52972 6 185 3.4E-58 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like STK_11980 773da258d2e06cd97a14a23fefa04682 276 SUPERFAMILY SSF54675 2 104 9.42E-24 T 23-10-2018 STK_11980 773da258d2e06cd97a14a23fefa04682 276 PIRSF PIRSF006250 1 276 1.2E-98 T 23-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 STK_11980 773da258d2e06cd97a14a23fefa04682 276 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 21 103 4.0E-21 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 STK_11980 773da258d2e06cd97a14a23fefa04682 276 SUPERFAMILY SSF51690 105 274 3.73E-58 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 STK_11980 773da258d2e06cd97a14a23fefa04682 276 Gene3D G3DSA:3.90.1170.20 12 271 2.4E-92 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 STK_11980 773da258d2e06cd97a14a23fefa04682 276 Gene3D G3DSA:3.20.20.70 121 263 2.4E-92 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_11980 773da258d2e06cd97a14a23fefa04682 276 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 10 272 3.0E-102 T 23-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 STK_11980 773da258d2e06cd97a14a23fefa04682 276 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 105 272 1.5E-60 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 STK_19140 cf1e8e8b835e26751b003df6a144f939 837 Pfam PF03176 MMPL family 674 831 2.0E-28 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 STK_19140 cf1e8e8b835e26751b003df6a144f939 837 Pfam PF03176 MMPL family 304 488 9.8E-24 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 STK_19140 cf1e8e8b835e26751b003df6a144f939 837 SUPERFAMILY SSF82866 265 476 8.5E-24 T 23-10-2018 STK_19140 cf1e8e8b835e26751b003df6a144f939 837 SUPERFAMILY SSF82866 672 827 5.1E-25 T 23-10-2018 STK_03820 0f73d656db67f30c53408794dbf14723 213 ProSitePatterns PS00578 Ribosomal protein S6e signature. 151 162 - T 23-10-2018 IPR018282 Ribosomal protein S6e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_03820 0f73d656db67f30c53408794dbf14723 213 SMART SM01405 112 212 5.0E-29 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_03820 0f73d656db67f30c53408794dbf14723 213 Hamap MF_00512 30S ribosomal protein S6e [rps6e]. 2 213 32.196 T 23-10-2018 IPR020924 Ribosomal protein S6e, archaeal GO:0003735|GO:0005840|GO:0006412 STK_03820 0f73d656db67f30c53408794dbf14723 213 Pfam PF01092 Ribosomal protein S6e 115 212 5.3E-24 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_07910 599464df70c633790cb5d6ba14d8796d 111 SUPERFAMILY SSF81593 2 104 6.67E-19 T 23-10-2018 STK_07910 599464df70c633790cb5d6ba14d8796d 111 Pfam PF05168 HEPN domain 2 97 8.3E-20 T 23-10-2018 IPR007842 HEPN domain STK_07910 599464df70c633790cb5d6ba14d8796d 111 Gene3D G3DSA:1.20.120.330 1 111 3.7E-17 T 23-10-2018 STK_07910 599464df70c633790cb5d6ba14d8796d 111 SMART SM00748 2 97 3.4E-13 T 23-10-2018 IPR007842 HEPN domain STK_01980 bcd007044dd103fca2217e6d1ef3e03c 195 Gene3D G3DSA:3.40.50.10490 1 194 2.1E-52 T 23-10-2018 STK_01980 bcd007044dd103fca2217e6d1ef3e03c 195 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 1 194 1.3E-70 T 23-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 STK_01980 bcd007044dd103fca2217e6d1ef3e03c 195 SUPERFAMILY SSF53697 3 193 1.9E-37 T 23-10-2018 STK_01980 bcd007044dd103fca2217e6d1ef3e03c 195 Pfam PF01380 SIS domain 37 134 3.5E-17 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 STK_24250 b955a427289c0d1e2eb88d0d8be367dd 238 Pfam PF04321 RmlD substrate binding domain 31 185 1.7E-19 T 23-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 STK_24250 b955a427289c0d1e2eb88d0d8be367dd 238 Gene3D G3DSA:3.40.50.720 32 194 1.4E-34 T 23-10-2018 STK_24250 b955a427289c0d1e2eb88d0d8be367dd 238 SUPERFAMILY SSF51735 32 213 8.23E-29 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_24250 b955a427289c0d1e2eb88d0d8be367dd 238 Gene3D G3DSA:3.90.25.10 142 211 1.4E-34 T 23-10-2018 STK_19040 8a5f6236c05a3d1e9632086ee16a8f80 136 Pfam PF01797 Transposase IS200 like 11 128 6.5E-43 T 23-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 STK_19040 8a5f6236c05a3d1e9632086ee16a8f80 136 SUPERFAMILY SSF143422 2 128 1.31E-49 T 23-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 STK_19040 8a5f6236c05a3d1e9632086ee16a8f80 136 Gene3D G3DSA:3.30.70.1290 1 136 1.7E-52 T 23-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 STK_19040 8a5f6236c05a3d1e9632086ee16a8f80 136 SMART SM01321 10 128 1.1E-47 T 23-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 STK_01490 dda91d091292866014e2b372f0b56181 239 Gene3D G3DSA:3.40.190.10 92 234 1.2E-7 T 23-10-2018 STK_01490 dda91d091292866014e2b372f0b56181 239 Pfam PF13531 Bacterial extracellular solute-binding protein 93 234 1.0E-7 T 23-10-2018 STK_01490 dda91d091292866014e2b372f0b56181 239 Gene3D G3DSA:3.40.190.10 101 199 1.2E-7 T 23-10-2018 STK_01490 dda91d091292866014e2b372f0b56181 239 SUPERFAMILY SSF53850 89 235 4.25E-15 T 23-10-2018 STK_24680 e5df910a492c5c813e7f8d5b6a599dfa 213 ProSitePatterns PS00397 Site-specific recombinases active site. 62 70 - T 23-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 STK_24680 e5df910a492c5c813e7f8d5b6a599dfa 213 Pfam PF12728 Helix-turn-helix domain 4 54 5.7E-16 T 23-10-2018 STK_24680 e5df910a492c5c813e7f8d5b6a599dfa 213 Gene3D G3DSA:3.40.50.1390 59 156 1.6E-27 T 23-10-2018 STK_24680 e5df910a492c5c813e7f8d5b6a599dfa 213 SMART SM00857 59 198 8.5E-27 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 STK_24680 e5df910a492c5c813e7f8d5b6a599dfa 213 SUPERFAMILY SSF46955 3 54 1.65E-8 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily STK_24680 e5df910a492c5c813e7f8d5b6a599dfa 213 Gene3D G3DSA:1.10.1660.10 5 58 1.1E-7 T 23-10-2018 STK_24680 e5df910a492c5c813e7f8d5b6a599dfa 213 Pfam PF00239 Resolvase, N terminal domain 59 188 2.9E-23 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 STK_24680 e5df910a492c5c813e7f8d5b6a599dfa 213 SUPERFAMILY SSF53041 58 188 2.35E-26 T 23-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 STK_24680 e5df910a492c5c813e7f8d5b6a599dfa 213 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 5 53 3.5E-19 T 23-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 STK_22690 7c8753f8b11e9c69a733d92c64f53605 313 Pfam PF02779 Transketolase, pyrimidine binding domain 7 167 3.4E-37 T 23-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain STK_22690 7c8753f8b11e9c69a733d92c64f53605 313 Gene3D G3DSA:3.40.50.970 5 181 1.2E-55 T 23-10-2018 STK_22690 7c8753f8b11e9c69a733d92c64f53605 313 Gene3D G3DSA:3.40.50.920 184 313 2.4E-37 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 STK_22690 7c8753f8b11e9c69a733d92c64f53605 313 Pfam PF02780 Transketolase, C-terminal domain 184 304 3.4E-29 T 23-10-2018 IPR033248 Transketolase, C-terminal domain STK_22690 7c8753f8b11e9c69a733d92c64f53605 313 SUPERFAMILY SSF52518 5 173 2.16E-53 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold STK_22690 7c8753f8b11e9c69a733d92c64f53605 313 SUPERFAMILY SSF52922 178 312 4.19E-35 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 STK_22690 7c8753f8b11e9c69a733d92c64f53605 313 SMART SM00861 7 172 1.5E-49 T 23-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain STK_06180 3944c6915444a3ec249f8d7b1c662602 466 Gene3D G3DSA:3.90.650.10 224 458 7.3E-12 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily STK_06180 3944c6915444a3ec249f8d7b1c662602 466 SUPERFAMILY SSF56042 325 443 7.85E-5 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily STK_06180 3944c6915444a3ec249f8d7b1c662602 466 PIRSF PIRSF032675 1 466 7.6E-260 T 23-10-2018 IPR017003 Uncharacterised conserved protein UCP032675 STK_17110 d9ddbc4eacfbc20f308cc359e0b922a1 587 Gene3D G3DSA:3.40.50.300 322 582 1.1E-78 T 23-10-2018 STK_17110 d9ddbc4eacfbc20f308cc359e0b922a1 587 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 95 226 5.4E-34 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_17110 d9ddbc4eacfbc20f308cc359e0b922a1 587 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 364 490 2.5E-36 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_17110 d9ddbc4eacfbc20f308cc359e0b922a1 587 SUPERFAMILY SSF52540 322 582 5.27E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_17110 d9ddbc4eacfbc20f308cc359e0b922a1 587 Gene3D G3DSA:3.40.50.300 62 303 2.2E-59 T 23-10-2018 STK_17110 d9ddbc4eacfbc20f308cc359e0b922a1 587 ProSitePatterns PS00674 AAA-protein family signature. 196 214 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 STK_17110 d9ddbc4eacfbc20f308cc359e0b922a1 587 SMART SM00382 91 228 4.3E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_17110 d9ddbc4eacfbc20f308cc359e0b922a1 587 SMART SM00382 360 493 3.4E-23 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_17110 d9ddbc4eacfbc20f308cc359e0b922a1 587 Pfam PF09336 Vps4 C terminal oligomerisation domain 553 582 1.2E-6 T 23-10-2018 IPR015415 Vps4 oligomerisation, C-terminal STK_17110 d9ddbc4eacfbc20f308cc359e0b922a1 587 Gene3D G3DSA:1.10.8.60 227 290 2.2E-59 T 23-10-2018 STK_17110 d9ddbc4eacfbc20f308cc359e0b922a1 587 Gene3D G3DSA:1.10.8.60 492 567 1.1E-78 T 23-10-2018 STK_17110 d9ddbc4eacfbc20f308cc359e0b922a1 587 ProSitePatterns PS00674 AAA-protein family signature. 461 479 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 STK_17110 d9ddbc4eacfbc20f308cc359e0b922a1 587 SUPERFAMILY SSF52540 62 307 5.06E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_04510 f8767d5c0c0a446d87a1cafb7a9a47c0 400 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 76 91 2.0E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 STK_04510 f8767d5c0c0a446d87a1cafb7a9a47c0 400 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 25 43 2.0E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 STK_04510 f8767d5c0c0a446d87a1cafb7a9a47c0 400 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 2.0E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 STK_04510 f8767d5c0c0a446d87a1cafb7a9a47c0 400 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 93 111 2.0E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 STK_04510 f8767d5c0c0a446d87a1cafb7a9a47c0 400 Gene3D G3DSA:3.40.50.300 4 271 2.3E-81 T 23-10-2018 STK_04510 f8767d5c0c0a446d87a1cafb7a9a47c0 400 SUPERFAMILY SSF81271 322 395 8.94E-17 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 STK_04510 f8767d5c0c0a446d87a1cafb7a9a47c0 400 Pfam PF08438 GTPase of unknown function C-terminal 224 328 8.2E-38 T 23-10-2018 IPR013646 Uncharacterised GTP-binding protein, C-terminal STK_04510 f8767d5c0c0a446d87a1cafb7a9a47c0 400 Gene3D G3DSA:1.10.8.470 129 219 2.3E-81 T 23-10-2018 STK_04510 f8767d5c0c0a446d87a1cafb7a9a47c0 400 Pfam PF01926 50S ribosome-binding GTPase 4 143 7.0E-20 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 STK_04510 f8767d5c0c0a446d87a1cafb7a9a47c0 400 SUPERFAMILY SSF52540 2 314 1.71E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_04510 f8767d5c0c0a446d87a1cafb7a9a47c0 400 Pfam PF02824 TGS domain 340 394 1.5E-11 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 STK_04510 f8767d5c0c0a446d87a1cafb7a9a47c0 400 Gene3D G3DSA:3.10.20.30 320 398 1.1E-29 T 23-10-2018 IPR012675 Beta-grasp domain superfamily STK_12940 2b669fef914a0307af58682b8313753e 532 Gene3D G3DSA:1.10.8.50 229 306 3.6E-25 T 23-10-2018 STK_12940 2b669fef914a0307af58682b8313753e 532 ProDom PD013790 TOPOISOMERASE ISOMERASE SUBUNIT DNA B VI TYPE II NUCLEOTIDE-BINDING ATP-BINDING 306 530 9.0E-118 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 STK_12940 2b669fef914a0307af58682b8313753e 532 SUPERFAMILY SSF54211 307 469 9.86E-64 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold STK_12940 2b669fef914a0307af58682b8313753e 532 Gene3D G3DSA:3.30.565.10 1 228 1.9E-69 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily STK_12940 2b669fef914a0307af58682b8313753e 532 SUPERFAMILY SSF55874 13 226 2.1E-38 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily STK_12940 2b669fef914a0307af58682b8313753e 532 Hamap MF_00322 Type 2 DNA topoisomerase 6 subunit B [top6B]. 3 505 29.259 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 STK_12940 2b669fef914a0307af58682b8313753e 532 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 29 119 1.6E-10 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase STK_12940 2b669fef914a0307af58682b8313753e 532 Gene3D G3DSA:3.30.230.10 307 532 4.9E-80 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup STK_12940 2b669fef914a0307af58682b8313753e 532 TIGRFAM TIGR01052 top6b: DNA topoisomerase VI, B subunit 4 486 1.5E-168 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 STK_12940 2b669fef914a0307af58682b8313753e 532 Pfam PF09239 Topoisomerase VI B subunit, transducer 308 467 1.6E-66 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 STK_12940 2b669fef914a0307af58682b8313753e 532 SMART SM00387 26 147 1.7E-5 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase STK_12940 2b669fef914a0307af58682b8313753e 532 SUPERFAMILY SSF46946 229 302 1.41E-15 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 STK_12940 2b669fef914a0307af58682b8313753e 532 PIRSF PIRSF006553 1 531 3.1E-204 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 STK_02570 106e9af292bb7d81cc37ef984186702c 412 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 192 378 1.1E-54 T 23-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 STK_02570 106e9af292bb7d81cc37ef984186702c 412 Gene3D G3DSA:3.40.50.10300 193 411 2.0E-61 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 STK_02570 106e9af292bb7d81cc37ef984186702c 412 Gene3D G3DSA:3.40.50.1950 14 192 3.6E-48 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 STK_02570 106e9af292bb7d81cc37ef984186702c 412 SUPERFAMILY SSF102645 190 406 1.2E-59 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 STK_02570 106e9af292bb7d81cc37ef984186702c 412 Pfam PF02441 Flavoprotein 20 164 7.9E-38 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 STK_02570 106e9af292bb7d81cc37ef984186702c 412 SUPERFAMILY SSF52507 19 216 3.53E-48 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 STK_02570 106e9af292bb7d81cc37ef984186702c 412 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 19 402 2.9E-100 T 23-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 STK_24420 a401bc3fe02913fbd82dfca707039e77 212 Pfam PF00578 AhpC/TSA family 9 138 2.2E-32 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 STK_24420 a401bc3fe02913fbd82dfca707039e77 212 Gene3D G3DSA:3.40.30.10 7 147 8.1E-47 T 23-10-2018 STK_24420 a401bc3fe02913fbd82dfca707039e77 212 SUPERFAMILY SSF52833 7 203 1.17E-67 T 23-10-2018 IPR036249 Thioredoxin-like superfamily STK_24420 a401bc3fe02913fbd82dfca707039e77 212 Hamap MF_00401 Peroxiredoxin. 7 212 52.514 T 23-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 STK_24420 a401bc3fe02913fbd82dfca707039e77 212 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 159 198 5.2E-12 T 23-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 STK_24420 a401bc3fe02913fbd82dfca707039e77 212 PIRSF PIRSF000239 2 212 1.9E-81 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 STK_24420 a401bc3fe02913fbd82dfca707039e77 212 Gene3D G3DSA:3.30.1020.20 148 212 9.2E-24 T 23-10-2018 STK_21650 f2fde3f03b77d5ae8d0b4c85a90d129a 386 Hamap MF_01407 ORC1-type DNA replication protein. 7 374 25.245 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea STK_21650 f2fde3f03b77d5ae8d0b4c85a90d129a 386 Gene3D G3DSA:1.10.10.10 293 383 9.1E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_21650 f2fde3f03b77d5ae8d0b4c85a90d129a 386 Pfam PF09079 CDC6, C terminal winged helix domain 311 372 6.7E-14 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 STK_21650 f2fde3f03b77d5ae8d0b4c85a90d129a 386 SMART SM01074 299 374 2.1E-19 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 STK_21650 f2fde3f03b77d5ae8d0b4c85a90d129a 386 SUPERFAMILY SSF52540 20 265 2.88E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_21650 f2fde3f03b77d5ae8d0b4c85a90d129a 386 SMART SM00382 53 203 2.4E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_21650 f2fde3f03b77d5ae8d0b4c85a90d129a 386 Gene3D G3DSA:3.40.50.300 39 206 2.1E-79 T 23-10-2018 STK_21650 f2fde3f03b77d5ae8d0b4c85a90d129a 386 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 23 360 1.8E-76 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea STK_21650 f2fde3f03b77d5ae8d0b4c85a90d129a 386 Pfam PF13401 AAA domain 57 187 5.5E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_21650 f2fde3f03b77d5ae8d0b4c85a90d129a 386 SUPERFAMILY SSF46785 283 379 2.18E-20 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_21650 f2fde3f03b77d5ae8d0b4c85a90d129a 386 Gene3D G3DSA:1.10.8.60 207 286 2.1E-79 T 23-10-2018 STK_25680 904cd88f9bdaff678ffdeb6cb20cff6e 412 Pfam PF14306 PUA-like domain 20 153 3.3E-38 T 23-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 STK_25680 904cd88f9bdaff678ffdeb6cb20cff6e 412 SUPERFAMILY SSF88697 19 160 7.75E-45 T 23-10-2018 IPR015947 PUA-like superfamily STK_25680 904cd88f9bdaff678ffdeb6cb20cff6e 412 Pfam PF01747 ATP-sulfurylase 163 383 2.1E-78 T 23-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 STK_25680 904cd88f9bdaff678ffdeb6cb20cff6e 412 Gene3D G3DSA:3.10.400.10 23 156 8.3E-41 T 23-10-2018 STK_25680 904cd88f9bdaff678ffdeb6cb20cff6e 412 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 18 383 4.0E-109 T 23-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 STK_25680 904cd88f9bdaff678ffdeb6cb20cff6e 412 SUPERFAMILY SSF52374 161 383 6.75E-71 T 23-10-2018 STK_25680 904cd88f9bdaff678ffdeb6cb20cff6e 412 Gene3D G3DSA:3.40.50.620 162 385 8.3E-81 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_14950 b78666eeabaf9c5f931caebe10500d2f 703 Gene3D G3DSA:3.90.650.10 17 347 4.6E-113 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily STK_14950 b78666eeabaf9c5f931caebe10500d2f 703 Gene3D G3DSA:3.30.1330.10 31 182 4.6E-113 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily STK_14950 b78666eeabaf9c5f931caebe10500d2f 703 Pfam PF02769 AIR synthase related protein, C-terminal domain 191 333 9.4E-28 T 23-10-2018 IPR010918 PurM-like, C-terminal domain STK_14950 b78666eeabaf9c5f931caebe10500d2f 703 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 5 698 2.3E-248 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 STK_14950 b78666eeabaf9c5f931caebe10500d2f 703 SUPERFAMILY SSF56042 542 699 2.99E-19 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily STK_14950 b78666eeabaf9c5f931caebe10500d2f 703 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 703 196.947 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 STK_14950 b78666eeabaf9c5f931caebe10500d2f 703 Gene3D G3DSA:3.30.1330.10 387 535 5.0E-40 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily STK_14950 b78666eeabaf9c5f931caebe10500d2f 703 Pfam PF00586 AIR synthase related protein, N-terminal domain 72 178 9.7E-20 T 23-10-2018 IPR016188 PurM-like, N-terminal domain STK_14950 b78666eeabaf9c5f931caebe10500d2f 703 Pfam PF00586 AIR synthase related protein, N-terminal domain 426 531 4.9E-14 T 23-10-2018 IPR016188 PurM-like, N-terminal domain STK_14950 b78666eeabaf9c5f931caebe10500d2f 703 SUPERFAMILY SSF56042 189 362 3.74E-38 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily STK_14950 b78666eeabaf9c5f931caebe10500d2f 703 SUPERFAMILY SSF55326 3 184 3.29E-44 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily STK_14950 b78666eeabaf9c5f931caebe10500d2f 703 SUPERFAMILY SSF55326 387 533 7.85E-35 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily STK_14950 b78666eeabaf9c5f931caebe10500d2f 703 Gene3D G3DSA:3.90.650.10 541 700 5.7E-12 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily STK_14950 b78666eeabaf9c5f931caebe10500d2f 703 PIRSF PIRSF001587 1 703 4.1E-214 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 STK_02610 c1e6dc0c86d98d9208daaf357ec22dab 305 SUPERFAMILY SSF81301 79 177 9.0E-7 T 23-10-2018 STK_04715 1226d22ae80776e03f177f768c69f83e 86 Gene3D G3DSA:1.10.10.10 2 83 2.1E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_04715 1226d22ae80776e03f177f768c69f83e 86 SUPERFAMILY SSF46785 4 82 7.04E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_04715 1226d22ae80776e03f177f768c69f83e 86 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 54 1.4E-7 T 23-10-2018 STK_03570 3e4f1ccdb6dc2dfbc19b565238097610 209 SUPERFAMILY SSF109755 6 204 1.47E-12 T 23-10-2018 STK_03570 3e4f1ccdb6dc2dfbc19b565238097610 209 Gene3D G3DSA:1.20.58.220 7 205 2.7E-14 T 23-10-2018 IPR038078 PhoU-like domain superfamily STK_03570 3e4f1ccdb6dc2dfbc19b565238097610 209 Pfam PF01865 Protein of unknown function DUF47 77 204 1.2E-5 T 23-10-2018 IPR018445 Putative phosphate transport regulator STK_00690 26a2a99fe3e16c0e00079438d47e1650 652 Gene3D G3DSA:1.10.12.10 593 652 6.2E-18 T 23-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal STK_00690 26a2a99fe3e16c0e00079438d47e1650 652 Pfam PF00378 Enoyl-CoA hydratase/isomerase 409 651 1.1E-67 T 23-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 STK_00690 26a2a99fe3e16c0e00079438d47e1650 652 SUPERFAMILY SSF52096 395 651 2.31E-88 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily STK_00690 26a2a99fe3e16c0e00079438d47e1650 652 Gene3D G3DSA:3.40.50.720 1 188 1.5E-68 T 23-10-2018 STK_00690 26a2a99fe3e16c0e00079438d47e1650 652 Gene3D G3DSA:3.90.226.10 389 591 1.6E-71 T 23-10-2018 STK_00690 26a2a99fe3e16c0e00079438d47e1650 652 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 493 513 - T 23-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 STK_00690 26a2a99fe3e16c0e00079438d47e1650 652 SUPERFAMILY SSF48179 306 413 2.47E-21 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 STK_00690 26a2a99fe3e16c0e00079438d47e1650 652 Gene3D G3DSA:1.10.1040.10 307 388 1.3E-19 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 STK_00690 26a2a99fe3e16c0e00079438d47e1650 652 SUPERFAMILY SSF51735 1 183 5.92E-60 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_00690 26a2a99fe3e16c0e00079438d47e1650 652 Gene3D G3DSA:1.10.1040.10 189 301 9.3E-27 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 STK_00690 26a2a99fe3e16c0e00079438d47e1650 652 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 187 281 4.1E-25 T 23-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 STK_00690 26a2a99fe3e16c0e00079438d47e1650 652 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 310 389 3.7E-15 T 23-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 STK_00690 26a2a99fe3e16c0e00079438d47e1650 652 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 184 1.1E-65 T 23-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 STK_00690 26a2a99fe3e16c0e00079438d47e1650 652 SUPERFAMILY SSF48179 186 295 1.96E-23 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 STK_19090 038bbd79477dd73f7cc4954b81ac56f9 370 Pfam PF02562 PhoH-like protein 2 202 3.6E-50 T 23-10-2018 IPR003714 PhoH-like protein GO:0005524 STK_19090 038bbd79477dd73f7cc4954b81ac56f9 370 Pfam PF07650 KH domain 242 297 4.7E-8 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_19090 038bbd79477dd73f7cc4954b81ac56f9 370 Gene3D G3DSA:3.40.50.300 1 202 4.8E-36 T 23-10-2018 STK_19090 038bbd79477dd73f7cc4954b81ac56f9 370 SMART SM00382 20 212 1.3E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_19090 038bbd79477dd73f7cc4954b81ac56f9 370 Gene3D G3DSA:3.30.300.20 253 296 1.0E-5 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta STK_19090 038bbd79477dd73f7cc4954b81ac56f9 370 SUPERFAMILY SSF52540 2 157 6.87E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_08290 9fdc38beef3700a02097e1b74eaa4462 238 Gene3D G3DSA:4.10.1060.10 16 46 5.1E-8 T 23-10-2018 STK_08290 9fdc38beef3700a02097e1b74eaa4462 238 SMART SM00240 159 209 1.4E-13 T 23-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 STK_08290 9fdc38beef3700a02097e1b74eaa4462 238 ProSitePatterns PS01358 Zinc finger RanBP2-type signature. 17 36 - T 23-10-2018 IPR001876 Zinc finger, RanBP2-type STK_08290 9fdc38beef3700a02097e1b74eaa4462 238 SMART SM00547 15 39 0.0058 T 23-10-2018 IPR001876 Zinc finger, RanBP2-type STK_08290 9fdc38beef3700a02097e1b74eaa4462 238 Pfam PF00498 FHA domain 161 228 4.4E-16 T 23-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 STK_08290 9fdc38beef3700a02097e1b74eaa4462 238 Gene3D G3DSA:2.60.200.20 129 238 4.4E-33 T 23-10-2018 STK_08290 9fdc38beef3700a02097e1b74eaa4462 238 SUPERFAMILY SSF49879 97 235 1.09E-22 T 23-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 STK_08290 9fdc38beef3700a02097e1b74eaa4462 238 Pfam PF13240 zinc-ribbon domain 18 38 5.9E-7 T 23-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 STK_14410 dba1a719279aaaf02f335c1c8dee5ed3 316 Pfam PF01680 SOR/SNZ family 28 232 8.9E-102 T 23-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 STK_14410 dba1a719279aaaf02f335c1c8dee5ed3 316 ProSitePatterns PS01235 PdxS/SNZ family signature. 225 243 - T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 STK_14410 dba1a719279aaaf02f335c1c8dee5ed3 316 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 24 316 51.274 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 STK_14410 dba1a719279aaaf02f335c1c8dee5ed3 316 PIRSF PIRSF029271 16 316 7.5E-149 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 STK_14410 dba1a719279aaaf02f335c1c8dee5ed3 316 SUPERFAMILY SSF51366 38 284 2.82E-62 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 STK_14410 dba1a719279aaaf02f335c1c8dee5ed3 316 Gene3D G3DSA:3.20.20.70 20 312 7.2E-129 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_06150 a7fe7b7aa5ce4868295c6ed54c52faa5 384 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 302 5.6E-12 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 STK_06150 a7fe7b7aa5ce4868295c6ed54c52faa5 384 Gene3D G3DSA:3.50.50.60 4 318 2.6E-92 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_06150 a7fe7b7aa5ce4868295c6ed54c52faa5 384 SUPERFAMILY SSF51905 121 253 4.47E-34 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_06150 a7fe7b7aa5ce4868295c6ed54c52faa5 384 Gene3D G3DSA:3.50.50.60 118 262 2.6E-92 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_06150 a7fe7b7aa5ce4868295c6ed54c52faa5 384 SUPERFAMILY SSF51905 1 154 1.3E-19 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_04330 2fbdcfb5a08358280c3368d3f53eee64 337 SUPERFAMILY SSF53659 4 336 3.46E-107 T 23-10-2018 STK_04330 2fbdcfb5a08358280c3368d3f53eee64 337 Gene3D G3DSA:3.40.718.10 2 337 1.1E-144 T 23-10-2018 STK_04330 2fbdcfb5a08358280c3368d3f53eee64 337 TIGRFAM TIGR02088 LEU3_arch: isopropylmalate/isohomocitrate dehydrogenases 5 333 1.4E-134 T 23-10-2018 IPR011828 Isopropylmalate/isohomocitrate dehydrogenase GO:0003862|GO:0009098|GO:0051287|GO:0055114 STK_04330 2fbdcfb5a08358280c3368d3f53eee64 337 SMART SM01329 4 332 1.7E-157 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 STK_04330 2fbdcfb5a08358280c3368d3f53eee64 337 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 221 240 - T 23-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 STK_04330 2fbdcfb5a08358280c3368d3f53eee64 337 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 332 4.2E-92 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 STK_15710 1eaad9ce5e1401b01788a15eabd3ec96 693 SUPERFAMILY SSF54665 2 139 5.5E-37 T 23-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily STK_15710 1eaad9ce5e1401b01788a15eabd3ec96 693 Gene3D G3DSA:3.30.365.10 417 555 1.1E-67 T 23-10-2018 STK_15710 1eaad9ce5e1401b01788a15eabd3ec96 693 Gene3D G3DSA:3.90.1170.50 26 118 8.2E-69 T 23-10-2018 STK_15710 1eaad9ce5e1401b01788a15eabd3ec96 693 Gene3D G3DSA:3.30.365.10 10 261 8.2E-69 T 23-10-2018 STK_15710 1eaad9ce5e1401b01788a15eabd3ec96 693 SUPERFAMILY SSF56003 110 691 4.58E-121 T 23-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 STK_15710 1eaad9ce5e1401b01788a15eabd3ec96 693 Gene3D G3DSA:3.30.365.10 346 690 1.1E-67 T 23-10-2018 STK_15710 1eaad9ce5e1401b01788a15eabd3ec96 693 Gene3D G3DSA:3.30.365.10 119 335 8.2E-69 T 23-10-2018 STK_15710 1eaad9ce5e1401b01788a15eabd3ec96 693 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 158 638 1.0E-91 T 23-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 STK_15710 1eaad9ce5e1401b01788a15eabd3ec96 693 SMART SM01008 11 118 2.0E-32 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead STK_15710 1eaad9ce5e1401b01788a15eabd3ec96 693 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 12 117 4.5E-26 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead STK_20580 2637a41211dca0d91c0cab05fb12d8aa 329 Pfam PF00348 Polyprenyl synthetase 27 277 2.5E-74 T 23-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 STK_20580 2637a41211dca0d91c0cab05fb12d8aa 329 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 207 219 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site STK_20580 2637a41211dca0d91c0cab05fb12d8aa 329 SUPERFAMILY SSF48576 2 328 3.45E-94 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily STK_20580 2637a41211dca0d91c0cab05fb12d8aa 329 Gene3D G3DSA:1.10.600.10 3 329 2.2E-102 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily STK_20580 2637a41211dca0d91c0cab05fb12d8aa 329 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 78 92 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site STK_00920 372c6d91c7f4427080e331588ae6b3c1 407 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 298 5.4E-65 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 STK_00920 372c6d91c7f4427080e331588ae6b3c1 407 SUPERFAMILY SSF51905 144 311 1.22E-33 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_00920 372c6d91c7f4427080e331588ae6b3c1 407 SUPERFAMILY SSF51905 4 188 1.08E-41 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_00920 372c6d91c7f4427080e331588ae6b3c1 407 Gene3D G3DSA:3.30.390.30 318 407 9.9E-11 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 STK_00920 372c6d91c7f4427080e331588ae6b3c1 407 SUPERFAMILY SSF55424 310 405 1.79E-16 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 STK_00920 372c6d91c7f4427080e331588ae6b3c1 407 Pfam PF14759 Reductase C-terminal 318 405 1.4E-11 T 23-10-2018 IPR028202 Reductase, C-terminal STK_00920 372c6d91c7f4427080e331588ae6b3c1 407 Gene3D G3DSA:3.50.50.60 8 306 4.0E-98 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_00920 372c6d91c7f4427080e331588ae6b3c1 407 Gene3D G3DSA:3.50.50.60 113 235 4.0E-98 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_00920 372c6d91c7f4427080e331588ae6b3c1 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 101 109 6.4E-11 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_00920 372c6d91c7f4427080e331588ae6b3c1 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 263 281 6.4E-11 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_00920 372c6d91c7f4427080e331588ae6b3c1 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 6.4E-11 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_00920 372c6d91c7f4427080e331588ae6b3c1 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 139 163 6.4E-11 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_00920 372c6d91c7f4427080e331588ae6b3c1 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 4.3E-26 T 23-10-2018 STK_00920 372c6d91c7f4427080e331588ae6b3c1 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.3E-26 T 23-10-2018 STK_00920 372c6d91c7f4427080e331588ae6b3c1 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 4.3E-26 T 23-10-2018 STK_00920 372c6d91c7f4427080e331588ae6b3c1 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 4.3E-26 T 23-10-2018 STK_00920 372c6d91c7f4427080e331588ae6b3c1 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 4.3E-26 T 23-10-2018 STK_02350 46aa4e7a08f29dd9469decec042c26a8 405 Gene3D G3DSA:3.30.300.340 14 286 9.8E-158 T 23-10-2018 STK_02350 46aa4e7a08f29dd9469decec042c26a8 405 Gene3D G3DSA:3.30.300.10 26 154 9.8E-158 T 23-10-2018 STK_02350 46aa4e7a08f29dd9469decec042c26a8 405 Gene3D G3DSA:3.30.300.280 13 398 9.8E-158 T 23-10-2018 STK_02350 46aa4e7a08f29dd9469decec042c26a8 405 Hamap MF_00136 S-adenosylmethionine synthase [mat]. 1 405 50.491 T 23-10-2018 IPR002795 S-adenosylmethionine synthetase, archaea GO:0004478|GO:0005524|GO:0006730 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 STK_02350 46aa4e7a08f29dd9469decec042c26a8 405 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 2 400 9.0E-173 T 23-10-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 STK_02350 46aa4e7a08f29dd9469decec042c26a8 405 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 20 399 0.0 T 23-10-2018 STK_21905 60ab10c762f357953cf03139dd63cb2a 81 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 45 4.8E-17 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_21905 60ab10c762f357953cf03139dd63cb2a 81 Gene3D G3DSA:2.10.260.10 4 44 1.9E-12 T 23-10-2018 STK_21905 60ab10c762f357953cf03139dd63cb2a 81 SUPERFAMILY SSF89447 4 46 3.84E-12 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily STK_21905 60ab10c762f357953cf03139dd63cb2a 81 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 6 47 1.0E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_21905 60ab10c762f357953cf03139dd63cb2a 81 SMART SM00966 6 51 2.2E-9 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_24700 4d4cc169dca7bc88d923731a9b932fe3 485 SUPERFAMILY SSF50998 96 477 1.13E-37 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily STK_24700 4d4cc169dca7bc88d923731a9b932fe3 485 Pfam PF01011 PQQ enzyme repeat 374 405 2.2E-5 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat STK_24700 4d4cc169dca7bc88d923731a9b932fe3 485 SMART SM00564 168 201 1.6 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat STK_24700 4d4cc169dca7bc88d923731a9b932fe3 485 SMART SM00564 258 294 290.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat STK_24700 4d4cc169dca7bc88d923731a9b932fe3 485 SMART SM00564 369 401 1.1 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat STK_24700 4d4cc169dca7bc88d923731a9b932fe3 485 SMART SM00564 209 241 0.11 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat STK_24700 4d4cc169dca7bc88d923731a9b932fe3 485 SMART SM00564 99 131 5.7E-5 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat STK_24700 4d4cc169dca7bc88d923731a9b932fe3 485 Gene3D G3DSA:2.130.10.10 268 482 5.8E-20 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 STK_24700 4d4cc169dca7bc88d923731a9b932fe3 485 Pfam PF13360 PQQ-like domain 98 308 1.0E-17 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat STK_24700 4d4cc169dca7bc88d923731a9b932fe3 485 Gene3D G3DSA:2.40.10.480 170 239 1.0E-12 T 23-10-2018 STK_24700 4d4cc169dca7bc88d923731a9b932fe3 485 Gene3D G3DSA:2.40.10.480 98 165 2.3E-10 T 23-10-2018 STK_09440 691ebc9dea1c3909e6123367a353bcd9 246 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 5 96 1.3E-11 T 23-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 STK_09440 691ebc9dea1c3909e6123367a353bcd9 246 Gene3D G3DSA:3.70.10.10 1 246 2.7E-62 T 23-10-2018 STK_09440 691ebc9dea1c3909e6123367a353bcd9 246 SUPERFAMILY SSF55979 125 246 2.64E-24 T 23-10-2018 STK_09440 691ebc9dea1c3909e6123367a353bcd9 246 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 55 79 1.7E-9 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 STK_09440 691ebc9dea1c3909e6123367a353bcd9 246 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 33 51 1.7E-9 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 STK_09440 691ebc9dea1c3909e6123367a353bcd9 246 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 231 246 1.7E-9 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 STK_09440 691ebc9dea1c3909e6123367a353bcd9 246 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 9 28 1.7E-9 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 STK_09440 691ebc9dea1c3909e6123367a353bcd9 246 SUPERFAMILY SSF55979 1 107 5.39E-30 T 23-10-2018 STK_09440 691ebc9dea1c3909e6123367a353bcd9 246 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 33 56 - T 23-10-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 STK_09440 691ebc9dea1c3909e6123367a353bcd9 246 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 137 243 2.6E-5 T 23-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 STK_09440 691ebc9dea1c3909e6123367a353bcd9 246 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 1 245 26.223 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 STK_15355 6f394392cced80c253a0f8507eeb97f2 77 SMART SM00966 4 49 2.7E-14 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_15355 6f394392cced80c253a0f8507eeb97f2 77 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 44 3.4E-19 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_15355 6f394392cced80c253a0f8507eeb97f2 77 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 47 1.8E-13 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_15355 6f394392cced80c253a0f8507eeb97f2 77 Gene3D G3DSA:2.10.260.10 3 41 5.0E-14 T 23-10-2018 STK_15355 6f394392cced80c253a0f8507eeb97f2 77 SUPERFAMILY SSF89447 1 45 2.09E-13 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily STK_20720 40360f3beea154e66d02dee42201b25b 134 PIRSF PIRSF004681 1 134 4.7E-43 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 STK_20720 40360f3beea154e66d02dee42201b25b 134 Pfam PF01894 Uncharacterised protein family UPF0047 20 130 2.4E-38 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 STK_20720 40360f3beea154e66d02dee42201b25b 134 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 96 114 - T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 STK_20720 40360f3beea154e66d02dee42201b25b 134 Gene3D G3DSA:2.60.120.460 1 134 7.7E-56 T 23-10-2018 IPR035917 YjbQ-like superfamily STK_20720 40360f3beea154e66d02dee42201b25b 134 SUPERFAMILY SSF111038 1 134 3.79E-43 T 23-10-2018 IPR035917 YjbQ-like superfamily STK_20720 40360f3beea154e66d02dee42201b25b 134 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 7 134 6.0E-40 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 STK_05040 c73fa376371d00706d0cea3e10ef9fdb 545 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 256 289 - T 23-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 STK_05040 c73fa376371d00706d0cea3e10ef9fdb 545 Pfam PF03454 MoeA C-terminal region (domain IV) 333 401 2.7E-10 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 STK_05040 c73fa376371d00706d0cea3e10ef9fdb 545 Gene3D G3DSA:2.40.340.10 330 397 1.5E-103 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 STK_05040 c73fa376371d00706d0cea3e10ef9fdb 545 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 180 313 5.8E-30 T 23-10-2018 IPR001453 MoaB/Mog domain STK_05040 c73fa376371d00706d0cea3e10ef9fdb 545 SUPERFAMILY SSF63882 11 179 1.02E-44 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 STK_05040 c73fa376371d00706d0cea3e10ef9fdb 545 SMART SM00852 183 321 4.7E-34 T 23-10-2018 IPR001453 MoaB/Mog domain STK_05040 c73fa376371d00706d0cea3e10ef9fdb 545 Pfam PF03453 MoeA N-terminal region (domain I and II) 14 170 6.0E-34 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 STK_05040 c73fa376371d00706d0cea3e10ef9fdb 545 Pfam PF00994 Probable molybdopterin binding domain 184 317 8.4E-29 T 23-10-2018 IPR001453 MoaB/Mog domain STK_05040 c73fa376371d00706d0cea3e10ef9fdb 545 SUPERFAMILY SSF63867 331 401 2.45E-9 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 STK_05040 c73fa376371d00706d0cea3e10ef9fdb 545 Gene3D G3DSA:3.40.980.10 178 329 1.5E-103 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily STK_05040 c73fa376371d00706d0cea3e10ef9fdb 545 SUPERFAMILY SSF53218 180 322 6.67E-39 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily STK_05040 c73fa376371d00706d0cea3e10ef9fdb 545 Gene3D G3DSA:3.90.105.10 31 177 1.5E-103 T 23-10-2018 STK_05040 c73fa376371d00706d0cea3e10ef9fdb 545 Gene3D G3DSA:2.170.190.11 55 144 1.5E-103 T 23-10-2018 STK_10100 19c892aae8fb6fb22d4ebd145d2a0e90 208 SUPERFAMILY SSF56524 22 205 1.7E-58 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 STK_10100 19c892aae8fb6fb22d4ebd145d2a0e90 208 Pfam PF00174 Oxidoreductase molybdopterin binding domain 51 197 3.3E-37 T 23-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 STK_10100 19c892aae8fb6fb22d4ebd145d2a0e90 208 Gene3D G3DSA:3.90.420.10 21 208 2.0E-46 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 STK_03530 8a5fce6b69c89c3ea737ecfe3de9dd71 571 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 2 552 3.9E-179 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 STK_03530 8a5fce6b69c89c3ea737ecfe3de9dd71 571 SUPERFAMILY SSF52954 450 555 1.5E-33 T 23-10-2018 STK_03530 8a5fce6b69c89c3ea737ecfe3de9dd71 571 PRINTS PR01043 Glycyl-tRNA synthetase signature 423 435 6.9E-52 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 STK_03530 8a5fce6b69c89c3ea737ecfe3de9dd71 571 PRINTS PR01043 Glycyl-tRNA synthetase signature 139 151 6.9E-52 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 STK_03530 8a5fce6b69c89c3ea737ecfe3de9dd71 571 PRINTS PR01043 Glycyl-tRNA synthetase signature 500 519 6.9E-52 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 STK_03530 8a5fce6b69c89c3ea737ecfe3de9dd71 571 PRINTS PR01043 Glycyl-tRNA synthetase signature 158 175 6.9E-52 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 STK_03530 8a5fce6b69c89c3ea737ecfe3de9dd71 571 PRINTS PR01043 Glycyl-tRNA synthetase signature 190 207 6.9E-52 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 STK_03530 8a5fce6b69c89c3ea737ecfe3de9dd71 571 PRINTS PR01043 Glycyl-tRNA synthetase signature 21 35 6.9E-52 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 STK_03530 8a5fce6b69c89c3ea737ecfe3de9dd71 571 PRINTS PR01043 Glycyl-tRNA synthetase signature 207 217 6.9E-52 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 STK_03530 8a5fce6b69c89c3ea737ecfe3de9dd71 571 SUPERFAMILY SSF55681 3 466 4.62E-111 T 23-10-2018 STK_03530 8a5fce6b69c89c3ea737ecfe3de9dd71 571 Gene3D G3DSA:1.10.30.30 347 417 4.4E-120 T 23-10-2018 STK_03530 8a5fce6b69c89c3ea737ecfe3de9dd71 571 Pfam PF03129 Anticodon binding domain 463 551 2.6E-19 T 23-10-2018 IPR004154 Anticodon-binding STK_03530 8a5fce6b69c89c3ea737ecfe3de9dd71 571 Gene3D G3DSA:1.20.1430.20 81 144 4.4E-120 T 23-10-2018 STK_03530 8a5fce6b69c89c3ea737ecfe3de9dd71 571 Gene3D G3DSA:3.30.930.10 8 448 4.4E-120 T 23-10-2018 STK_03530 8a5fce6b69c89c3ea737ecfe3de9dd71 571 Gene3D G3DSA:3.40.50.800 455 568 1.2E-32 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily STK_11970 50ecf0a093feddf359a3fd732174783f 308 Pfam PF02445 Quinolinate synthetase A protein 5 303 3.0E-104 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 STK_11970 50ecf0a093feddf359a3fd732174783f 308 Gene3D G3DSA:3.40.50.10800 5 286 6.9E-107 T 23-10-2018 STK_11970 50ecf0a093feddf359a3fd732174783f 308 Gene3D G3DSA:3.40.50.10800 85 303 6.9E-107 T 23-10-2018 STK_11970 50ecf0a093feddf359a3fd732174783f 308 Gene3D G3DSA:3.40.50.10800 170 261 6.9E-107 T 23-10-2018 STK_11970 50ecf0a093feddf359a3fd732174783f 308 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 3 305 2.1E-99 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 STK_11970 50ecf0a093feddf359a3fd732174783f 308 Hamap MF_00568 Quinolinate synthase A [nadA]. 1 305 43.788 T 23-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 STK_11970 50ecf0a093feddf359a3fd732174783f 308 SUPERFAMILY SSF142754 2 304 3.14E-103 T 23-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 STK_01550 df2069540163d6ec05656262d85513a9 353 Gene3D G3DSA:3.20.20.140 1 353 8.3E-74 T 23-10-2018 STK_01550 df2069540163d6ec05656262d85513a9 353 SUPERFAMILY SSF51556 139 352 9.91E-17 T 23-10-2018 IPR032466 Metal-dependent hydrolase STK_01550 df2069540163d6ec05656262d85513a9 353 Pfam PF04909 Amidohydrolase 17 353 4.2E-42 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 STK_01300 93a7694cad10cd7f87c5a89269a181dc 267 PRINTS PR00069 Aldo-keto reductase signature 41 65 3.2E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 STK_01300 93a7694cad10cd7f87c5a89269a181dc 267 PRINTS PR00069 Aldo-keto reductase signature 97 115 3.2E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 STK_01300 93a7694cad10cd7f87c5a89269a181dc 267 PRINTS PR00069 Aldo-keto reductase signature 127 144 3.2E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 STK_01300 93a7694cad10cd7f87c5a89269a181dc 267 PRINTS PR00069 Aldo-keto reductase signature 200 224 3.2E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 STK_01300 93a7694cad10cd7f87c5a89269a181dc 267 SUPERFAMILY SSF51430 8 266 3.54E-79 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily STK_01300 93a7694cad10cd7f87c5a89269a181dc 267 Pfam PF00248 Aldo/keto reductase family 11 265 2.4E-61 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain STK_01300 93a7694cad10cd7f87c5a89269a181dc 267 Gene3D G3DSA:3.20.20.100 5 265 9.0E-84 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily STK_01300 93a7694cad10cd7f87c5a89269a181dc 267 PIRSF PIRSF000097 116 267 1.0E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 STK_01300 93a7694cad10cd7f87c5a89269a181dc 267 PIRSF PIRSF000097 9 118 7.5E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 STK_18270 adf7ea4c944be659ba105c305e9bf5e5 271 SUPERFAMILY SSF56235 5 265 5.92E-71 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_18270 adf7ea4c944be659ba105c305e9bf5e5 271 Pfam PF01112 Asparaginase 6 122 2.2E-29 T 23-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 STK_18270 adf7ea4c944be659ba105c305e9bf5e5 271 Pfam PF01112 Asparaginase 134 261 4.1E-39 T 23-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 STK_18270 adf7ea4c944be659ba105c305e9bf5e5 271 Gene3D G3DSA:3.60.20.30 137 270 6.2E-37 T 23-10-2018 STK_04540 f41791a9aa177a3a2c51ad30108f8a63 227 Pfam PF00588 SpoU rRNA Methylase family 2 149 2.5E-31 T 23-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 STK_04540 f41791a9aa177a3a2c51ad30108f8a63 227 SUPERFAMILY SSF75217 3 157 2.15E-31 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases STK_04540 f41791a9aa177a3a2c51ad30108f8a63 227 PIRSF PIRSF004808 1 226 2.3E-55 T 23-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 STK_04540 f41791a9aa177a3a2c51ad30108f8a63 227 Gene3D G3DSA:3.40.1280.10 1 154 2.7E-49 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal STK_02090 0817dc590383ceb2738ccf682a7e8285 773 Gene3D G3DSA:2.40.40.20 14 107 2.2E-30 T 23-10-2018 STK_02090 0817dc590383ceb2738ccf682a7e8285 773 SMART SM01072 124 187 1.0E-17 T 23-10-2018 IPR004201 CDC48, domain 2 STK_02090 0817dc590383ceb2738ccf682a7e8285 773 Gene3D G3DSA:3.10.330.10 108 186 1.5E-7 T 23-10-2018 STK_02090 0817dc590383ceb2738ccf682a7e8285 773 SUPERFAMILY SSF54585 109 198 4.25E-20 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily STK_02090 0817dc590383ceb2738ccf682a7e8285 773 Gene3D G3DSA:3.40.50.300 458 637 6.2E-73 T 23-10-2018 STK_02090 0817dc590383ceb2738ccf682a7e8285 773 Gene3D G3DSA:3.40.50.300 187 363 6.3E-72 T 23-10-2018 STK_02090 0817dc590383ceb2738ccf682a7e8285 773 SUPERFAMILY SSF52540 190 455 2.46E-76 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_02090 0817dc590383ceb2738ccf682a7e8285 773 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 506 636 8.1E-48 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_02090 0817dc590383ceb2738ccf682a7e8285 773 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 233 363 6.1E-49 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_02090 0817dc590383ceb2738ccf682a7e8285 773 SUPERFAMILY SSF52540 464 756 6.37E-77 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_02090 0817dc590383ceb2738ccf682a7e8285 773 Gene3D G3DSA:1.10.8.60 364 451 1.7E-34 T 23-10-2018 STK_02090 0817dc590383ceb2738ccf682a7e8285 773 ProSitePatterns PS00674 AAA-protein family signature. 333 351 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 STK_02090 0817dc590383ceb2738ccf682a7e8285 773 SMART SM01073 20 109 3.1E-35 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain STK_02090 0817dc590383ceb2738ccf682a7e8285 773 SUPERFAMILY SSF50692 16 106 5.84E-24 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily STK_02090 0817dc590383ceb2738ccf682a7e8285 773 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 125 186 1.6E-16 T 23-10-2018 IPR004201 CDC48, domain 2 STK_02090 0817dc590383ceb2738ccf682a7e8285 773 Gene3D G3DSA:1.10.8.60 638 759 5.5E-29 T 23-10-2018 STK_02090 0817dc590383ceb2738ccf682a7e8285 773 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 21 759 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 STK_02090 0817dc590383ceb2738ccf682a7e8285 773 SMART SM00382 229 365 3.0E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_02090 0817dc590383ceb2738ccf682a7e8285 773 SMART SM00382 502 639 6.2E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_02090 0817dc590383ceb2738ccf682a7e8285 773 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 21 107 1.1E-31 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain STK_02090 0817dc590383ceb2738ccf682a7e8285 773 ProSitePatterns PS00674 AAA-protein family signature. 607 625 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 STK_03580 70ba47b7558cfeae1a403a6e8c7b6cde 180 Gene3D G3DSA:3.40.1350.10 86 180 8.7E-34 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 STK_03580 70ba47b7558cfeae1a403a6e8c7b6cde 180 Pfam PF02778 tRNA intron endonuclease, N-terminal domain 1 77 2.4E-21 T 23-10-2018 IPR006678 tRNA intron endonuclease, N-terminal GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 STK_03580 70ba47b7558cfeae1a403a6e8c7b6cde 180 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 87 172 3.0E-28 T 23-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 STK_03580 70ba47b7558cfeae1a403a6e8c7b6cde 180 Hamap MF_01833 tRNA-splicing endonuclease [endA]. 1 180 36.684 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 STK_03580 70ba47b7558cfeae1a403a6e8c7b6cde 180 PIRSF PIRSF005285 4 180 1.1E-66 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 STK_03580 70ba47b7558cfeae1a403a6e8c7b6cde 180 TIGRFAM TIGR00324 endA: tRNA-intron lyase 42 177 5.1E-28 T 23-10-2018 IPR006676 tRNA-splicing endonuclease GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 STK_03580 70ba47b7558cfeae1a403a6e8c7b6cde 180 Gene3D G3DSA:3.40.1170.20 1 85 3.0E-33 T 23-10-2018 STK_03580 70ba47b7558cfeae1a403a6e8c7b6cde 180 SUPERFAMILY SSF53032 85 170 4.01E-26 T 23-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 STK_03580 70ba47b7558cfeae1a403a6e8c7b6cde 180 SUPERFAMILY SSF55267 1 81 3.73E-16 T 23-10-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 STK_03184 22446d463aa023bd1dca697d3edd3fc5 78 SUPERFAMILY SSF116820 2 60 4.05E-20 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_03184 22446d463aa023bd1dca697d3edd3fc5 78 Hamap MF_00511 30S ribosomal protein S17e [rps17e]. 1 63 17.946 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_03184 22446d463aa023bd1dca697d3edd3fc5 78 Pfam PF00833 Ribosomal S17 2 66 3.5E-14 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_03184 22446d463aa023bd1dca697d3edd3fc5 78 ProSitePatterns PS00712 Ribosomal protein S17e signature. 41 56 - T 23-10-2018 IPR018273 Ribosomal protein S17e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_03184 22446d463aa023bd1dca697d3edd3fc5 78 Gene3D G3DSA:1.10.60.20 1 62 7.8E-23 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_06800 00aff97784153ce7df56ab71ccbda2d3 136 Pfam PF01797 Transposase IS200 like 11 128 1.7E-42 T 23-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 STK_06800 00aff97784153ce7df56ab71ccbda2d3 136 SMART SM01321 10 128 1.8E-46 T 23-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 STK_06800 00aff97784153ce7df56ab71ccbda2d3 136 Gene3D G3DSA:3.30.70.1290 1 136 1.9E-52 T 23-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 STK_06800 00aff97784153ce7df56ab71ccbda2d3 136 SUPERFAMILY SSF143422 2 128 3.92E-49 T 23-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 STK_13870 881db079e022b7d810b120399fd8b54d 473 SUPERFAMILY SSF54368 7 102 1.29E-27 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 STK_13870 881db079e022b7d810b120399fd8b54d 473 Gene3D G3DSA:3.30.590.10 110 461 9.2E-129 T 23-10-2018 STK_13870 881db079e022b7d810b120399fd8b54d 473 SMART SM01230 107 383 5.0E-129 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 STK_13870 881db079e022b7d810b120399fd8b54d 473 SUPERFAMILY SSF55931 107 472 3.24E-120 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 STK_13870 881db079e022b7d810b120399fd8b54d 473 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 258 273 - T 23-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 STK_13870 881db079e022b7d810b120399fd8b54d 473 ProSitePatterns PS00180 Glutamine synthetase signature 1. 56 74 - T 23-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 STK_13870 881db079e022b7d810b120399fd8b54d 473 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 9 472 4.5E-179 T 23-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 STK_13870 881db079e022b7d810b120399fd8b54d 473 Pfam PF00120 Glutamine synthetase, catalytic domain 107 470 4.2E-134 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 STK_13870 881db079e022b7d810b120399fd8b54d 473 Gene3D G3DSA:3.10.20.70 7 109 3.4E-30 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 STK_13870 881db079e022b7d810b120399fd8b54d 473 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 19 99 1.3E-25 T 23-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 STK_23570 52ba9cd17a93f614ad7a858d97e9a123 767 SUPERFAMILY SSF55729 311 586 3.73E-11 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase STK_23570 52ba9cd17a93f614ad7a858d97e9a123 767 Pfam PF05127 Helicase 226 404 1.8E-46 T 23-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 STK_23570 52ba9cd17a93f614ad7a858d97e9a123 767 Pfam PF08351 Domain of unknown function (DUF1726) 82 166 3.7E-25 T 23-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 STK_23570 52ba9cd17a93f614ad7a858d97e9a123 767 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 21 742 41.488 T 23-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 STK_23570 52ba9cd17a93f614ad7a858d97e9a123 767 Pfam PF13718 GNAT acetyltransferase 2 437 553 4.6E-26 T 23-10-2018 IPR000182 GNAT domain STK_23570 52ba9cd17a93f614ad7a858d97e9a123 767 Gene3D G3DSA:3.40.630.30 397 601 2.0E-48 T 23-10-2018 STK_23570 52ba9cd17a93f614ad7a858d97e9a123 767 SUPERFAMILY SSF52540 127 350 2.39E-7 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_23570 52ba9cd17a93f614ad7a858d97e9a123 767 Gene3D G3DSA:3.40.50.12320 222 394 9.8E-26 T 23-10-2018 STK_00500 cbfac0c93fa60db22899a8f56c0ddc38 562 ProSitePatterns PS00455 Putative AMP-binding domain signature. 193 204 - T 23-10-2018 IPR020845 AMP-binding, conserved site STK_00500 cbfac0c93fa60db22899a8f56c0ddc38 562 SUPERFAMILY SSF56801 42 557 6.41E-149 T 23-10-2018 STK_00500 cbfac0c93fa60db22899a8f56c0ddc38 562 Gene3D G3DSA:3.30.300.30 438 562 5.2E-35 T 23-10-2018 STK_00500 cbfac0c93fa60db22899a8f56c0ddc38 562 Pfam PF13193 AMP-binding enzyme C-terminal domain 451 529 1.2E-22 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain STK_00500 cbfac0c93fa60db22899a8f56c0ddc38 562 Pfam PF00501 AMP-binding enzyme 50 443 1.2E-82 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 STK_00500 cbfac0c93fa60db22899a8f56c0ddc38 562 Gene3D G3DSA:3.40.50.12780 6 436 2.1E-107 T 23-10-2018 STK_25370 17e817be963bf02a3ccff950cb0ae809 312 Gene3D G3DSA:3.40.50.300 1 312 1.1E-65 T 23-10-2018 STK_25370 17e817be963bf02a3ccff950cb0ae809 312 SUPERFAMILY SSF52540 1 249 3.99E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_25370 17e817be963bf02a3ccff950cb0ae809 312 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 291 1.0E-12 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 STK_25370 17e817be963bf02a3ccff950cb0ae809 312 SMART SM00382 33 222 9.6E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_25370 17e817be963bf02a3ccff950cb0ae809 312 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 229 309 1.4E-10 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 STK_25370 17e817be963bf02a3ccff950cb0ae809 312 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 STK_25370 17e817be963bf02a3ccff950cb0ae809 312 Pfam PF00005 ABC transporter 38 174 3.0E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_15500 2d76506de1db86d87d57cbd70b718c74 230 Gene3D G3DSA:3.40.50.150 17 211 1.5E-25 T 23-10-2018 STK_15500 2d76506de1db86d87d57cbd70b718c74 230 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 21 36 - T 23-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 STK_15500 2d76506de1db86d87d57cbd70b718c74 230 Pfam PF01209 ubiE/COQ5 methyltransferase family 4 185 3.8E-21 T 23-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 STK_15500 2d76506de1db86d87d57cbd70b718c74 230 SUPERFAMILY SSF53335 7 204 1.08E-21 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_11440 281f96b69a7666afd1e5dc4ac9d73fcf 248 Gene3D G3DSA:3.40.50.300 87 219 4.6E-7 T 23-10-2018 STK_11440 281f96b69a7666afd1e5dc4ac9d73fcf 248 SUPERFAMILY SSF52540 113 213 3.59E-8 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_11440 281f96b69a7666afd1e5dc4ac9d73fcf 248 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 165 204 1.8E-7 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_21880 a85815fc8c4c82fc0a9204aa14b11b7b 422 SMART SM00849 15 218 9.7E-16 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_21880 a85815fc8c4c82fc0a9204aa14b11b7b 422 Gene3D G3DSA:3.60.15.10 8 401 8.7E-103 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_21880 a85815fc8c4c82fc0a9204aa14b11b7b 422 Pfam PF16661 Metallo-beta-lactamase superfamily domain 27 173 4.4E-10 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_21880 a85815fc8c4c82fc0a9204aa14b11b7b 422 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 354 412 3.4E-14 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain STK_21880 a85815fc8c4c82fc0a9204aa14b11b7b 422 SUPERFAMILY SSF56281 5 420 4.32E-105 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_21880 a85815fc8c4c82fc0a9204aa14b11b7b 422 Pfam PF10996 Beta-Casp domain 242 341 1.7E-16 T 23-10-2018 IPR022712 Beta-Casp domain STK_21880 a85815fc8c4c82fc0a9204aa14b11b7b 422 Gene3D G3DSA:3.40.50.10890 199 367 8.7E-103 T 23-10-2018 STK_21880 a85815fc8c4c82fc0a9204aa14b11b7b 422 SMART SM01027 231 341 5.4E-33 T 23-10-2018 IPR022712 Beta-Casp domain STK_18520 ba3cc33dea190077a9e4a7fe7e870cc6 415 SUPERFAMILY SSF103473 32 399 1.03E-41 T 23-10-2018 IPR036259 MFS transporter superfamily STK_18520 ba3cc33dea190077a9e4a7fe7e870cc6 415 Pfam PF07690 Major Facilitator Superfamily 39 249 6.8E-23 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_18520 ba3cc33dea190077a9e4a7fe7e870cc6 415 Gene3D G3DSA:1.20.1250.20 31 213 3.3E-18 T 23-10-2018 STK_18520 ba3cc33dea190077a9e4a7fe7e870cc6 415 Gene3D G3DSA:1.20.1250.20 215 403 4.2E-14 T 23-10-2018 STK_17740 81ab34c89eef99543c3d437efe71a275 129 Pfam PF00571 CBS domain 68 119 1.1E-10 T 23-10-2018 IPR000644 CBS domain STK_17740 81ab34c89eef99543c3d437efe71a275 129 Pfam PF00571 CBS domain 3 57 3.2E-12 T 23-10-2018 IPR000644 CBS domain STK_17740 81ab34c89eef99543c3d437efe71a275 129 SMART SM00116 73 120 9.8E-6 T 23-10-2018 IPR000644 CBS domain STK_17740 81ab34c89eef99543c3d437efe71a275 129 SMART SM00116 10 57 1.8E-7 T 23-10-2018 IPR000644 CBS domain STK_17740 81ab34c89eef99543c3d437efe71a275 129 Gene3D G3DSA:3.10.580.10 1 128 1.3E-32 T 23-10-2018 STK_17740 81ab34c89eef99543c3d437efe71a275 129 SUPERFAMILY SSF54631 1 119 1.24E-28 T 23-10-2018 STK_01000 e56642e06db8c163c717a34826c8f533 121 Gene3D G3DSA:3.40.50.720 2 121 5.6E-22 T 23-10-2018 STK_01000 e56642e06db8c163c717a34826c8f533 121 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 14 120 2.0E-12 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 STK_01000 e56642e06db8c163c717a34826c8f533 121 SUPERFAMILY SSF51735 13 119 2.64E-17 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_16220 646390619c59f695b7ba3c0c82c916a6 340 Pfam PF00586 AIR synthase related protein, N-terminal domain 47 137 3.6E-11 T 23-10-2018 IPR016188 PurM-like, N-terminal domain STK_16220 646390619c59f695b7ba3c0c82c916a6 340 SUPERFAMILY SSF55326 11 144 2.24E-23 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily STK_16220 646390619c59f695b7ba3c0c82c916a6 340 SUPERFAMILY SSF56042 153 325 1.27E-27 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily STK_16220 646390619c59f695b7ba3c0c82c916a6 340 Pfam PF02769 AIR synthase related protein, C-terminal domain 158 312 6.2E-17 T 23-10-2018 IPR010918 PurM-like, C-terminal domain STK_16220 646390619c59f695b7ba3c0c82c916a6 340 Gene3D G3DSA:3.90.650.10 150 333 4.4E-34 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily STK_16220 646390619c59f695b7ba3c0c82c916a6 340 Gene3D G3DSA:3.30.1330.10 2 147 2.6E-24 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily STK_16220 646390619c59f695b7ba3c0c82c916a6 340 PIRSF PIRSF005644 1 333 1.2E-116 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE STK_26400 0a7b5d78ecf7fc96be5d0e450f4f1d4d 227 Gene3D G3DSA:1.10.3210.30 1 192 1.9E-28 T 23-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily STK_26400 0a7b5d78ecf7fc96be5d0e450f4f1d4d 227 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 12 199 2.4E-12 T 23-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain STK_14100 3208a0cf83322614b4178867a504b5fa 288 SUPERFAMILY SSF50129 12 147 9.95E-9 T 23-10-2018 IPR011032 GroES-like superfamily STK_14100 3208a0cf83322614b4178867a504b5fa 288 Gene3D G3DSA:3.90.180.10 1 154 6.6E-8 T 23-10-2018 STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 Gene3D G3DSA:3.40.50.140 573 756 6.0E-30 T 23-10-2018 STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 Pfam PF01131 DNA topoisomerase 750 1132 2.7E-73 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 SUPERFAMILY SSF56712 572 1141 6.15E-129 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 SUPERFAMILY SSF52540 27 269 3.13E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 SMART SM00493 574 726 3.6E-28 T 23-10-2018 IPR006171 TOPRIM domain STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 SUPERFAMILY SSF52540 297 553 1.77E-29 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 Pfam PF01751 Toprim domain 576 736 8.7E-23 T 23-10-2018 IPR006171 TOPRIM domain STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 TIGRFAM TIGR01054 rgy: reverse gyrase 1 1142 0.0 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 786 804 4.5E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 971 987 4.5E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1056 1070 4.5E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 700 713 4.5E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 890 899 4.5E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 SMART SM00436 727 828 1.9E-30 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 Gene3D G3DSA:1.10.460.10 757 1136 2.8E-126 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 SMART SM00437 848 1095 6.1E-77 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 Hamap MF_01125 Reverse gyrase [rgy]. 1 1143 61.716 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 Gene3D G3DSA:2.60.510.20 808 1040 2.8E-126 T 23-10-2018 STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 SMART SM00487 78 281 1.5E-14 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 Gene3D G3DSA:1.10.290.10 858 982 2.8E-126 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 Gene3D G3DSA:3.40.50.300 280 474 3.2E-20 T 23-10-2018 STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 Gene3D G3DSA:3.40.50.300 480 572 6.3E-10 T 23-10-2018 STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 Pfam PF00270 DEAD/DEAH box helicase 85 260 1.4E-6 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 STK_12900 8bb63098a34d4d711bb7193fbaa941ea 1156 Gene3D G3DSA:3.40.50.300 63 277 7.2E-43 T 23-10-2018 STK_04350 aa961e5ef05aba1115f4d87b124491e8 448 Pfam PF04389 Peptidase family M28 172 327 5.3E-5 T 23-10-2018 IPR007484 Peptidase M28 STK_04350 aa961e5ef05aba1115f4d87b124491e8 448 PIRSF PIRSF032806 2 448 1.5E-224 T 23-10-2018 IPR014573 Uncharacterised conserved protein UCP032806 STK_04350 aa961e5ef05aba1115f4d87b124491e8 448 Gene3D G3DSA:3.40.630.10 139 337 1.1E-15 T 23-10-2018 STK_04350 aa961e5ef05aba1115f4d87b124491e8 448 SUPERFAMILY SSF53187 3 317 4.63E-19 T 23-10-2018 STK_17580 97be729307c0809374b754be3bd9f020 108 Gene3D G3DSA:3.30.460.10 4 106 1.7E-12 T 23-10-2018 STK_17580 97be729307c0809374b754be3bd9f020 108 Pfam PF01909 Nucleotidyltransferase domain 21 100 7.9E-10 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_17580 97be729307c0809374b754be3bd9f020 108 SUPERFAMILY SSF81301 10 105 3.51E-14 T 23-10-2018 STK_23940 0dd05138307ff23043b5244131b7a3da 217 ProDom PD003655 COPPER ELECTRON AZURIN METAL-BINDING PERIPLASMIC PRECURSOR SIGNAL SEQUENCING DIRECT MEMBRANE 103 204 0.008 T 23-10-2018 STK_23940 0dd05138307ff23043b5244131b7a3da 217 PIRSF PIRSF022145 1 217 5.8E-82 T 23-10-2018 IPR010532 Sulfocyanin GO:0005507|GO:0055114 STK_23940 0dd05138307ff23043b5244131b7a3da 217 SUPERFAMILY SSF49503 65 206 2.53E-23 T 23-10-2018 IPR008972 Cupredoxin STK_23940 0dd05138307ff23043b5244131b7a3da 217 TIGRFAM TIGR03094 sulfo_cyanin: sulfocyanin 51 216 6.7E-56 T 23-10-2018 IPR010532 Sulfocyanin GO:0005507|GO:0055114 STK_23940 0dd05138307ff23043b5244131b7a3da 217 ProSitePatterns PS00079 Multicopper oxidases signature 1. 184 204 - T 23-10-2018 IPR033138 Multicopper oxidases, conserved site STK_23940 0dd05138307ff23043b5244131b7a3da 217 Gene3D G3DSA:2.60.40.420 36 206 2.4E-23 T 23-10-2018 IPR008972 Cupredoxin STK_23940 0dd05138307ff23043b5244131b7a3da 217 Pfam PF06525 Sulfocyanin (SoxE) domain 70 216 8.9E-61 T 23-10-2018 IPR010532 Sulfocyanin GO:0005507|GO:0055114 STK_06900 bbd90aa85c4ebb81eb216a1adb2d4884 117 Gene3D G3DSA:3.30.460.10 1 84 3.2E-14 T 23-10-2018 STK_06900 bbd90aa85c4ebb81eb216a1adb2d4884 117 Pfam PF01909 Nucleotidyltransferase domain 3 97 1.1E-9 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_06900 bbd90aa85c4ebb81eb216a1adb2d4884 117 SUPERFAMILY SSF81301 2 97 1.36E-15 T 23-10-2018 STK_09400 223e9bd2b0ed52b2e68171132e7f121a 767 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 41 515 8.3E-13 T 23-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 STK_09400 223e9bd2b0ed52b2e68171132e7f121a 767 Gene3D G3DSA:3.40.50.12610 468 579 2.8E-18 T 23-10-2018 STK_18260 da0828039784f5109c44b1c9d703a594 319 Gene3D G3DSA:3.30.420.180 198 319 5.4E-28 T 23-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 STK_18260 da0828039784f5109c44b1c9d703a594 319 Pfam PF11760 Cobalamin synthesis G N-terminal 40 116 3.6E-28 T 23-10-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 STK_18260 da0828039784f5109c44b1c9d703a594 319 SUPERFAMILY SSF159672 4 206 9.42E-50 T 23-10-2018 IPR038029 GbiG N-terminal domain superfamily KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 STK_18260 da0828039784f5109c44b1c9d703a594 319 SUPERFAMILY SSF159664 200 317 1.16E-23 T 23-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 STK_18260 da0828039784f5109c44b1c9d703a594 319 Gene3D G3DSA:3.40.1390.40 121 197 1.4E-12 T 23-10-2018 STK_18260 da0828039784f5109c44b1c9d703a594 319 Pfam PF01890 Cobalamin synthesis G C-terminus 200 316 3.1E-16 T 23-10-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 STK_18260 da0828039784f5109c44b1c9d703a594 319 Gene3D G3DSA:3.40.50.11220 1 111 8.2E-37 T 23-10-2018 STK_26000 83caefc7b2b0f139fd8e83ef98df445f 331 Gene3D G3DSA:3.30.70.20 4 62 1.1E-7 T 23-10-2018 STK_26000 83caefc7b2b0f139fd8e83ef98df445f 331 Gene3D G3DSA:3.10.580.10 217 314 1.8E-13 T 23-10-2018 STK_26000 83caefc7b2b0f139fd8e83ef98df445f 331 SMART SM00116 87 133 1.9 T 23-10-2018 IPR000644 CBS domain STK_26000 83caefc7b2b0f139fd8e83ef98df445f 331 SMART SM00116 219 264 1.2 T 23-10-2018 IPR000644 CBS domain STK_26000 83caefc7b2b0f139fd8e83ef98df445f 331 SMART SM00116 145 193 4.7E-9 T 23-10-2018 IPR000644 CBS domain STK_26000 83caefc7b2b0f139fd8e83ef98df445f 331 SMART SM00116 277 324 38.0 T 23-10-2018 IPR000644 CBS domain STK_26000 83caefc7b2b0f139fd8e83ef98df445f 331 Pfam PF00571 CBS domain 80 132 8.1E-4 T 23-10-2018 IPR000644 CBS domain STK_26000 83caefc7b2b0f139fd8e83ef98df445f 331 Pfam PF00571 CBS domain 145 191 1.4E-9 T 23-10-2018 IPR000644 CBS domain STK_26000 83caefc7b2b0f139fd8e83ef98df445f 331 Pfam PF00571 CBS domain 215 262 3.0E-6 T 23-10-2018 IPR000644 CBS domain STK_26000 83caefc7b2b0f139fd8e83ef98df445f 331 SUPERFAMILY SSF54631 79 191 4.75E-20 T 23-10-2018 STK_26000 83caefc7b2b0f139fd8e83ef98df445f 331 Gene3D G3DSA:3.10.580.10 71 216 3.1E-24 T 23-10-2018 STK_26000 83caefc7b2b0f139fd8e83ef98df445f 331 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 45 56 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_26000 83caefc7b2b0f139fd8e83ef98df445f 331 Pfam PF13237 4Fe-4S dicluster domain 5 56 1.8E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_26000 83caefc7b2b0f139fd8e83ef98df445f 331 SUPERFAMILY SSF54631 212 310 2.91E-14 T 23-10-2018 STK_26000 83caefc7b2b0f139fd8e83ef98df445f 331 SUPERFAMILY SSF54862 5 72 1.0E-13 T 23-10-2018 STK_14420 95c68fd50d05c7835cae0c2460a81be8 200 SUPERFAMILY SSF52317 2 198 1.06E-47 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_14420 95c68fd50d05c7835cae0c2460a81be8 200 Gene3D G3DSA:3.40.50.880 1 200 2.9E-59 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_14420 95c68fd50d05c7835cae0c2460a81be8 200 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 3 197 32.414 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 STK_14420 95c68fd50d05c7835cae0c2460a81be8 200 ProSitePatterns PS01236 PdxT/SNO family family signature. 46 56 - T 23-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 STK_14420 95c68fd50d05c7835cae0c2460a81be8 200 PIRSF PIRSF005639 1 200 1.1E-65 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 STK_14420 95c68fd50d05c7835cae0c2460a81be8 200 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 2 196 5.6E-56 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 STK_14420 95c68fd50d05c7835cae0c2460a81be8 200 Pfam PF01174 SNO glutamine amidotransferase family 6 198 2.2E-45 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 Pfam PF00384 Molybdopterin oxidoreductase 310 732 3.7E-88 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 SUPERFAMILY SSF54292 14 82 5.66E-14 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 Pfam PF01568 Molydopterin dinucleotide binding domain 817 925 2.5E-21 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 Gene3D G3DSA:3.10.20.740 1 123 5.3E-31 T 23-10-2018 STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 81 120 1.8E-10 T 23-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 74 5.6E-10 T 23-10-2018 STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 SUPERFAMILY SSF54862 73 207 1.84E-30 T 23-10-2018 STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 PIRSF PIRSF036643 1 963 0.0 T 23-10-2018 STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 Gene3D G3DSA:2.40.40.20 806 937 3.1E-30 T 23-10-2018 STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 SMART SM00929 81 122 6.4E-14 T 23-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 SUPERFAMILY SSF53706 190 804 2.62E-204 T 23-10-2018 STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 258 928 1.5E-303 T 23-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 SUPERFAMILY SSF50692 789 931 1.65E-35 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 Pfam PF00037 4Fe-4S binding domain 184 201 4.1E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 Pfam PF00037 4Fe-4S binding domain 136 154 5.1E-5 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 Gene3D G3DSA:3.40.50.740 315 775 1.2E-175 T 23-10-2018 STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 SMART SM00926 253 307 2.4E-18 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 Gene3D G3DSA:2.20.25.90 253 307 7.2E-19 T 23-10-2018 STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 Gene3D G3DSA:3.40.228.10 388 587 1.2E-175 T 23-10-2018 STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 186 197 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 678 695 - T 23-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 253 307 2.4E-18 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_00810 c0ad7859a5daa66c1a34bb435bfbb8fc 973 Gene3D G3DSA:3.30.70.20 124 204 1.0E-19 T 23-10-2018 STK_09280 7bd9b50621046d60c7cc6eee81c237f4 716 Gene3D G3DSA:2.60.40.10 1 151 2.0E-53 T 23-10-2018 IPR013783 Immunoglobulin-like fold STK_09280 7bd9b50621046d60c7cc6eee81c237f4 716 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 17 108 7.6E-19 T 23-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 STK_09280 7bd9b50621046d60c7cc6eee81c237f4 716 Gene3D G3DSA:2.60.40.1180 610 716 6.3E-41 T 23-10-2018 IPR013780 Glycosyl hydrolase, all-beta STK_09280 7bd9b50621046d60c7cc6eee81c237f4 716 SUPERFAMILY SSF81296 12 160 1.54E-44 T 23-10-2018 IPR014756 Immunoglobulin E-set STK_09280 7bd9b50621046d60c7cc6eee81c237f4 716 Gene3D G3DSA:3.20.20.80 153 600 3.2E-176 T 23-10-2018 STK_09280 7bd9b50621046d60c7cc6eee81c237f4 716 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 13 712 0.0 T 23-10-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 STK_09280 7bd9b50621046d60c7cc6eee81c237f4 716 SMART SM00642 176 586 4.2E-9 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 STK_09280 7bd9b50621046d60c7cc6eee81c237f4 716 SUPERFAMILY SSF51445 148 594 2.64E-130 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily STK_09280 7bd9b50621046d60c7cc6eee81c237f4 716 Pfam PF00128 Alpha amylase, catalytic domain 204 293 9.4E-8 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 STK_09280 7bd9b50621046d60c7cc6eee81c237f4 716 SUPERFAMILY SSF51011 608 712 1.8E-12 T 23-10-2018 STK_12530 ba00d4f1496cea355d316f3a782011e6 559 Gene3D G3DSA:3.50.7.10 222 376 1.2E-201 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily STK_12530 ba00d4f1496cea355d316f3a782011e6 559 SUPERFAMILY SSF54849 152 409 7.02E-25 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily STK_12530 ba00d4f1496cea355d316f3a782011e6 559 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 37 49 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_12530 ba00d4f1496cea355d316f3a782011e6 559 Gene3D G3DSA:1.10.560.10 25 529 1.2E-201 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily STK_12530 ba00d4f1496cea355d316f3a782011e6 559 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 56 74 3.5E-32 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_12530 ba00d4f1496cea355d316f3a782011e6 559 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 379 401 3.5E-32 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_12530 ba00d4f1496cea355d316f3a782011e6 559 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 34 50 3.5E-32 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_12530 ba00d4f1496cea355d316f3a782011e6 559 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 86 105 3.5E-32 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_12530 ba00d4f1496cea355d316f3a782011e6 559 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 413 425 3.5E-32 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_12530 ba00d4f1496cea355d316f3a782011e6 559 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 5 531 6.5E-251 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 STK_12530 ba00d4f1496cea355d316f3a782011e6 559 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 58 74 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_12530 ba00d4f1496cea355d316f3a782011e6 559 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 86 94 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_12530 ba00d4f1496cea355d316f3a782011e6 559 Gene3D G3DSA:3.30.260.10 144 411 1.2E-201 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily STK_12530 ba00d4f1496cea355d316f3a782011e6 559 Pfam PF00118 TCP-1/cpn60 chaperonin family 32 532 1.8E-176 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 STK_12530 ba00d4f1496cea355d316f3a782011e6 559 SUPERFAMILY SSF52029 218 384 9.21E-59 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily STK_12530 ba00d4f1496cea355d316f3a782011e6 559 SUPERFAMILY SSF48592 14 532 1.57E-88 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily STK_20560 e0093d0af3197d17a8cfc791596786bf 361 SUPERFAMILY SSF51735 155 327 1.28E-47 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_20560 e0093d0af3197d17a8cfc791596786bf 361 Gene3D G3DSA:3.90.180.10 6 356 4.5E-121 T 23-10-2018 STK_20560 e0093d0af3197d17a8cfc791596786bf 361 SMART SM00829 11 359 4.0E-6 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 STK_20560 e0093d0af3197d17a8cfc791596786bf 361 Gene3D G3DSA:3.40.50.720 171 306 4.5E-121 T 23-10-2018 STK_20560 e0093d0af3197d17a8cfc791596786bf 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 149 7.6E-30 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 STK_20560 e0093d0af3197d17a8cfc791596786bf 361 Pfam PF00107 Zinc-binding dehydrogenase 193 316 6.6E-31 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 STK_20560 e0093d0af3197d17a8cfc791596786bf 361 SUPERFAMILY SSF50129 1 175 7.81E-61 T 23-10-2018 IPR011032 GroES-like superfamily STK_20560 e0093d0af3197d17a8cfc791596786bf 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 23-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 STK_13970 d7d45cf9de8aeaec597d2921323d39b6 474 Gene3D G3DSA:3.40.50.300 191 473 1.2E-74 T 23-10-2018 STK_13970 d7d45cf9de8aeaec597d2921323d39b6 474 Gene3D G3DSA:3.30.450.380 1 189 6.2E-39 T 23-10-2018 STK_13970 d7d45cf9de8aeaec597d2921323d39b6 474 Pfam PF00437 Type II/IV secretion system protein 129 343 1.2E-39 T 23-10-2018 IPR001482 Type II/IV secretion system protein STK_13970 d7d45cf9de8aeaec597d2921323d39b6 474 SUPERFAMILY SSF52540 72 380 9.57E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_17540 81a1c9c620b265175bb8d9a7649ebc42 132 SMART SM00748 10 123 5.7E-39 T 23-10-2018 IPR007842 HEPN domain STK_17540 81a1c9c620b265175bb8d9a7649ebc42 132 SUPERFAMILY SSF81593 8 130 1.41E-26 T 23-10-2018 STK_17540 81a1c9c620b265175bb8d9a7649ebc42 132 Gene3D G3DSA:1.20.120.330 2 132 1.8E-23 T 23-10-2018 STK_17540 81a1c9c620b265175bb8d9a7649ebc42 132 Pfam PF05168 HEPN domain 7 128 5.7E-23 T 23-10-2018 IPR007842 HEPN domain STK_24190 89246048a65e6ef2e63a133d52ebad05 128 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 58 117 7.0E-9 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal STK_24190 89246048a65e6ef2e63a133d52ebad05 128 SUPERFAMILY SSF50249 10 117 1.16E-29 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_24190 89246048a65e6ef2e63a133d52ebad05 128 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 21 57 5.2E-10 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal STK_24190 89246048a65e6ef2e63a133d52ebad05 128 Gene3D G3DSA:1.10.12.20 4 61 3.0E-15 T 23-10-2018 STK_20230 415482f05f79e36b1536a3f7587168b3 438 Pfam PF00206 Lyase 2 315 9.3E-104 T 23-10-2018 IPR022761 Fumarate lyase, N-terminal STK_20230 415482f05f79e36b1536a3f7587168b3 438 SUPERFAMILY SSF48557 4 430 3.61E-114 T 23-10-2018 IPR008948 L-Aspartase-like GO:0003824 STK_20230 415482f05f79e36b1536a3f7587168b3 438 PRINTS PR00149 Fumarate lyase superfamily signature 242 269 6.4E-27 T 23-10-2018 IPR000362 Fumarate lyase family STK_20230 415482f05f79e36b1536a3f7587168b3 438 PRINTS PR00149 Fumarate lyase superfamily signature 106 124 6.4E-27 T 23-10-2018 IPR000362 Fumarate lyase family STK_20230 415482f05f79e36b1536a3f7587168b3 438 PRINTS PR00149 Fumarate lyase superfamily signature 290 306 6.4E-27 T 23-10-2018 IPR000362 Fumarate lyase family STK_20230 415482f05f79e36b1536a3f7587168b3 438 PRINTS PR00149 Fumarate lyase superfamily signature 152 170 6.4E-27 T 23-10-2018 IPR000362 Fumarate lyase family STK_20230 415482f05f79e36b1536a3f7587168b3 438 PRINTS PR00145 Argininosuccinate lyase family signature 105 127 3.9E-8 T 23-10-2018 STK_20230 415482f05f79e36b1536a3f7587168b3 438 PRINTS PR00145 Argininosuccinate lyase family signature 147 167 3.9E-8 T 23-10-2018 STK_20230 415482f05f79e36b1536a3f7587168b3 438 PRINTS PR00145 Argininosuccinate lyase family signature 290 306 3.9E-8 T 23-10-2018 STK_20230 415482f05f79e36b1536a3f7587168b3 438 Gene3D G3DSA:1.10.40.30 380 435 1.7E-11 T 23-10-2018 STK_20230 415482f05f79e36b1536a3f7587168b3 438 Gene3D G3DSA:1.20.200.10 111 379 6.8E-85 T 23-10-2018 STK_20230 415482f05f79e36b1536a3f7587168b3 438 Pfam PF10415 Fumarase C C-terminus 381 431 1.5E-11 T 23-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 STK_20230 415482f05f79e36b1536a3f7587168b3 438 Gene3D G3DSA:1.10.275.10 1 110 1.4E-35 T 23-10-2018 IPR024083 Fumarase/histidase, N-terminal STK_20230 415482f05f79e36b1536a3f7587168b3 438 ProSitePatterns PS00163 Fumarate lyases signature. 290 299 - T 23-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 STK_12790 b3d4ef54c69593fa91f6d559b153fb4c 228 SUPERFAMILY SSF158372 1 79 1.05E-19 T 23-10-2018 IPR036809 AF1782-like superfamily STK_12790 b3d4ef54c69593fa91f6d559b153fb4c 228 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 87 149 7.8E-15 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 STK_12790 b3d4ef54c69593fa91f6d559b153fb4c 228 Gene3D G3DSA:3.40.50.620 84 205 4.8E-32 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_12790 b3d4ef54c69593fa91f6d559b153fb4c 228 Gene3D G3DSA:1.20.1270.90 1 81 3.2E-22 T 23-10-2018 STK_12790 b3d4ef54c69593fa91f6d559b153fb4c 228 Pfam PF01467 Cytidylyltransferase-like 89 218 5.4E-17 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 STK_12790 b3d4ef54c69593fa91f6d559b153fb4c 228 SUPERFAMILY SSF52374 87 222 1.39E-18 T 23-10-2018 STK_12790 b3d4ef54c69593fa91f6d559b153fb4c 228 Pfam PF04010 Protein of unknown function (DUF357) 11 74 4.2E-19 T 23-10-2018 IPR023140 Domain of unknown function DUF357 STK_04950 04ef7ed9bae4ac9d20bea25d8937dc9c 533 Pfam PF09843 Predicted membrane protein (DUF2070) 8 520 9.8E-110 T 23-10-2018 IPR019204 Domain of unknown function DUF2070, membrane STK_00470 531250606438d5ea882948b8c64b6628 560 Gene3D G3DSA:3.30.365.10 178 270 8.5E-52 T 23-10-2018 STK_00470 531250606438d5ea882948b8c64b6628 560 SMART SM01008 11 124 1.0E-35 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead STK_00470 531250606438d5ea882948b8c64b6628 560 Gene3D G3DSA:3.30.365.10 136 343 8.5E-52 T 23-10-2018 STK_00470 531250606438d5ea882948b8c64b6628 560 Gene3D G3DSA:3.30.365.10 355 437 1.7E-33 T 23-10-2018 STK_00470 531250606438d5ea882948b8c64b6628 560 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 12 123 3.2E-25 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead STK_00470 531250606438d5ea882948b8c64b6628 560 SUPERFAMILY SSF54665 4 137 5.5E-38 T 23-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily STK_00470 531250606438d5ea882948b8c64b6628 560 Gene3D G3DSA:3.90.1170.50 1 123 3.1E-32 T 23-10-2018 STK_00470 531250606438d5ea882948b8c64b6628 560 SUPERFAMILY SSF56003 116 547 1.05E-87 T 23-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 STK_00470 531250606438d5ea882948b8c64b6628 560 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 138 547 1.3E-85 T 23-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 STK_00470 531250606438d5ea882948b8c64b6628 560 Gene3D G3DSA:3.30.365.10 438 546 1.7E-33 T 23-10-2018 STK_17960 1d265d5082e28f21e9f125ac945e8a95 609 Gene3D G3DSA:3.40.50.12780 69 487 9.3E-81 T 23-10-2018 STK_17960 1d265d5082e28f21e9f125ac945e8a95 609 Pfam PF13193 AMP-binding enzyme C-terminal domain 500 573 8.9E-17 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain STK_17960 1d265d5082e28f21e9f125ac945e8a95 609 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 32 80 8.0E-11 T 23-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 STK_17960 1d265d5082e28f21e9f125ac945e8a95 609 SUPERFAMILY SSF56801 25 604 8.37E-133 T 23-10-2018 STK_17960 1d265d5082e28f21e9f125ac945e8a95 609 Pfam PF00501 AMP-binding enzyme 98 491 8.1E-71 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 STK_17960 1d265d5082e28f21e9f125ac945e8a95 609 Gene3D G3DSA:3.30.300.30 488 609 3.3E-22 T 23-10-2018 STK_17960 1d265d5082e28f21e9f125ac945e8a95 609 ProSitePatterns PS00455 Putative AMP-binding domain signature. 243 254 - T 23-10-2018 IPR020845 AMP-binding, conserved site STK_20955 de9218e901459dd643f975717759ebbf 64 PIRSF PIRSF036912 1 64 7.1E-46 T 23-10-2018 IPR003212 DNA-binding 7kDa protein GO:0003677|GO:0004521 STK_20955 de9218e901459dd643f975717759ebbf 64 Gene3D G3DSA:2.40.50.40 1 64 1.7E-38 T 23-10-2018 STK_20955 de9218e901459dd643f975717759ebbf 64 ProDom PD010328 DNA-BINDING METHYLATION DIRECT SEQUENCING 3D-STRUCTURE A 7A 3.1.27.- P2 7D 9 61 5.0E-21 T 23-10-2018 IPR003212 DNA-binding 7kDa protein GO:0003677|GO:0004521 STK_20955 de9218e901459dd643f975717759ebbf 64 SUPERFAMILY SSF54160 1 62 1.51E-34 T 23-10-2018 IPR016197 Chromo-like domain superfamily STK_20955 de9218e901459dd643f975717759ebbf 64 Pfam PF02294 7kD DNA-binding domain 3 60 1.9E-41 T 23-10-2018 IPR003212 DNA-binding 7kDa protein GO:0003677|GO:0004521 STK_06395 de9218e901459dd643f975717759ebbf 64 PIRSF PIRSF036912 1 64 7.1E-46 T 23-10-2018 IPR003212 DNA-binding 7kDa protein GO:0003677|GO:0004521 STK_06395 de9218e901459dd643f975717759ebbf 64 Gene3D G3DSA:2.40.50.40 1 64 1.7E-38 T 23-10-2018 STK_06395 de9218e901459dd643f975717759ebbf 64 ProDom PD010328 DNA-BINDING METHYLATION DIRECT SEQUENCING 3D-STRUCTURE A 7A 3.1.27.- P2 7D 9 61 5.0E-21 T 23-10-2018 IPR003212 DNA-binding 7kDa protein GO:0003677|GO:0004521 STK_06395 de9218e901459dd643f975717759ebbf 64 SUPERFAMILY SSF54160 1 62 1.51E-34 T 23-10-2018 IPR016197 Chromo-like domain superfamily STK_06395 de9218e901459dd643f975717759ebbf 64 Pfam PF02294 7kD DNA-binding domain 3 60 1.9E-41 T 23-10-2018 IPR003212 DNA-binding 7kDa protein GO:0003677|GO:0004521 STK_20300 5a874684c38f5550a7c7a5a0a5b1763c 229 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 207 3.8E-47 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_20300 5a874684c38f5550a7c7a5a0a5b1763c 229 Hamap MF_00147_A Triosephosphate isomerase [tpiA]. 3 221 38.454 T 23-10-2018 IPR022891 Triosephosphate isomerase, archaeal GO:0004807|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003 STK_20300 5a874684c38f5550a7c7a5a0a5b1763c 229 Gene3D G3DSA:3.20.20.70 1 224 2.0E-78 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_20300 5a874684c38f5550a7c7a5a0a5b1763c 229 SUPERFAMILY SSF51351 3 217 4.97E-43 T 23-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_20300 5a874684c38f5550a7c7a5a0a5b1763c 229 Pfam PF00121 Triosephosphate isomerase 5 120 2.8E-13 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_14540 f984db64d276fb420804615360ff239b 177 SUPERFAMILY SSF89028 1 172 3.53E-55 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 STK_14540 f984db64d276fb420804615360ff239b 177 Pfam PF01923 Cobalamin adenosyltransferase 1 159 1.2E-47 T 23-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 STK_14540 f984db64d276fb420804615360ff239b 177 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 7 172 2.0E-91 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 STK_14540 f984db64d276fb420804615360ff239b 177 Gene3D G3DSA:1.20.1200.10 19 177 1.7E-56 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 STK_14540 f984db64d276fb420804615360ff239b 177 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 2 172 7.7E-70 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 STK_24350 6d389775ed9da644babf2fa8daf36a29 628 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 93 611 1.0E-160 T 23-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 STK_24350 6d389775ed9da644babf2fa8daf36a29 628 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 13 212 2.1E-39 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 STK_24350 6d389775ed9da644babf2fa8daf36a29 628 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 513 607 5.7E-9 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II STK_24350 6d389775ed9da644babf2fa8daf36a29 628 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 242 488 2.8E-58 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 STK_24350 6d389775ed9da644babf2fa8daf36a29 628 Gene3D G3DSA:3.40.50.970 218 423 5.9E-67 T 23-10-2018 STK_24350 6d389775ed9da644babf2fa8daf36a29 628 SUPERFAMILY SSF52922 511 621 5.5E-20 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 STK_24350 6d389775ed9da644babf2fa8daf36a29 628 SUPERFAMILY SSF52518 229 496 1.9E-54 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold STK_24350 6d389775ed9da644babf2fa8daf36a29 628 Gene3D G3DSA:3.40.50.920 503 617 4.7E-29 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 STK_24350 6d389775ed9da644babf2fa8daf36a29 628 SUPERFAMILY SSF53323 7 225 2.09E-14 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 STK_24350 6d389775ed9da644babf2fa8daf36a29 628 Gene3D G3DSA:3.40.920.10 96 217 1.7E-6 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 STK_24350 6d389775ed9da644babf2fa8daf36a29 628 Gene3D G3DSA:3.40.920.10 2 95 3.7E-6 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 STK_14770 acdb2d093ca69a32dbb6c814c53d19bd 288 SUPERFAMILY SSF51395 2 277 8.06E-57 T 23-10-2018 STK_14770 acdb2d093ca69a32dbb6c814c53d19bd 288 Pfam PF01180 Dihydroorotate dehydrogenase 3 271 6.7E-50 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 STK_14770 acdb2d093ca69a32dbb6c814c53d19bd 288 Gene3D G3DSA:2.30.26.10 50 200 9.6E-67 T 23-10-2018 IPR023359 Dihydroorotate dehydrogenase A, chain A, domain 2 STK_14770 acdb2d093ca69a32dbb6c814c53d19bd 288 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 1 285 28.747 T 23-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 STK_14770 acdb2d093ca69a32dbb6c814c53d19bd 288 PIRSF PIRSF000164 2 287 3.5E-67 T 23-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 STK_14770 acdb2d093ca69a32dbb6c814c53d19bd 288 Gene3D G3DSA:3.20.20.70 8 277 9.6E-67 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_14770 acdb2d093ca69a32dbb6c814c53d19bd 288 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 2 285 3.0E-67 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 STK_14770 acdb2d093ca69a32dbb6c814c53d19bd 288 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 223 243 - T 23-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 STK_14930 dd7a5599f5617307f51a45bd6a01e70c 234 Gene3D G3DSA:3.30.470.20 83 220 1.8E-83 T 23-10-2018 STK_14930 dd7a5599f5617307f51a45bd6a01e70c 234 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 6 205 3.7E-61 T 23-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 STK_14930 dd7a5599f5617307f51a45bd6a01e70c 234 SUPERFAMILY SSF56104 5 232 4.25E-73 T 23-10-2018 STK_14930 dd7a5599f5617307f51a45bd6a01e70c 234 Pfam PF01259 SAICAR synthetase 6 228 2.9E-55 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 STK_14930 dd7a5599f5617307f51a45bd6a01e70c 234 Gene3D G3DSA:3.30.200.20 6 231 1.8E-83 T 23-10-2018 STK_14930 dd7a5599f5617307f51a45bd6a01e70c 234 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 3 234 28.707 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 STK_14930 dd7a5599f5617307f51a45bd6a01e70c 234 ProSitePatterns PS01057 SAICAR synthetase signature 1. 84 98 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 STK_17910 2603bab20ab37e0ac6b37ce6c18c3e3f 399 Gene3D G3DSA:1.10.540.10 4 129 2.0E-31 T 23-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 STK_17910 2603bab20ab37e0ac6b37ce6c18c3e3f 399 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 16 127 2.1E-27 T 23-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 STK_17910 2603bab20ab37e0ac6b37ce6c18c3e3f 399 PIRSF PIRSF016578 10 108 0.0065 T 23-10-2018 STK_17910 2603bab20ab37e0ac6b37ce6c18c3e3f 399 PIRSF PIRSF016578 132 396 1.1E-14 T 23-10-2018 STK_17910 2603bab20ab37e0ac6b37ce6c18c3e3f 399 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 131 228 2.2E-21 T 23-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 STK_17910 2603bab20ab37e0ac6b37ce6c18c3e3f 399 SUPERFAMILY SSF47203 238 391 9.83E-42 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 STK_17910 2603bab20ab37e0ac6b37ce6c18c3e3f 399 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 241 389 8.0E-35 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 STK_17910 2603bab20ab37e0ac6b37ce6c18c3e3f 399 SUPERFAMILY SSF56645 10 251 7.33E-73 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 STK_17910 2603bab20ab37e0ac6b37ce6c18c3e3f 399 Gene3D G3DSA:2.40.110.10 130 245 8.2E-37 T 23-10-2018 STK_17910 2603bab20ab37e0ac6b37ce6c18c3e3f 399 Gene3D G3DSA:1.20.140.10 246 395 3.5E-39 T 23-10-2018 STK_24800 aac4775a11dbd72e3a467cc7d7767659 265 SUPERFAMILY SSF103481 178 264 4.05E-8 T 23-10-2018 STK_24800 aac4775a11dbd72e3a467cc7d7767659 265 Pfam PF00892 EamA-like transporter family 4 125 7.4E-9 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 STK_24800 aac4775a11dbd72e3a467cc7d7767659 265 Pfam PF00892 EamA-like transporter family 135 264 1.1E-11 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 STK_12180 af19698e68acaab2f4483fdbb689c34f 313 Gene3D G3DSA:3.40.50.720 9 302 6.5E-115 T 23-10-2018 STK_12180 af19698e68acaab2f4483fdbb689c34f 313 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 9 309 5.4E-35 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 STK_12180 af19698e68acaab2f4483fdbb689c34f 313 SUPERFAMILY SSF51735 105 286 4.2E-45 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_12180 af19698e68acaab2f4483fdbb689c34f 313 SUPERFAMILY SSF52283 20 121 8.88E-33 T 23-10-2018 STK_12180 af19698e68acaab2f4483fdbb689c34f 313 Gene3D G3DSA:3.40.50.720 97 287 6.5E-115 T 23-10-2018 STK_12180 af19698e68acaab2f4483fdbb689c34f 313 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 145 172 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 STK_12180 af19698e68acaab2f4483fdbb689c34f 313 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 285 1.5E-50 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 STK_00990 8384dfd9a3080c7e1e6da914875fd8da 321 Pfam PF03400 IS1 transposase 177 284 6.3E-12 T 23-10-2018 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 STK_01900 d1fa16b83a32d97ba07b034daca9df9a 346 Hamap MF_01120 [LysW]-lysine/[LysW]-ornithine hydrolase [lysK]. 10 342 30.679 T 23-10-2018 IPR010175 [LysW]-lysine/[LysW]-ornithine hydrolase GO:0005737|GO:0008270|GO:0009085|GO:0016811|GO:0050897 STK_01900 d1fa16b83a32d97ba07b034daca9df9a 346 TIGRFAM TIGR01902 dapE-lys-deAc: N-acetyl-ornithine/N-acetyl-lysine deacetylase 14 342 3.0E-108 T 23-10-2018 IPR010175 [LysW]-lysine/[LysW]-ornithine hydrolase GO:0005737|GO:0008270|GO:0009085|GO:0016811|GO:0050897 STK_01900 d1fa16b83a32d97ba07b034daca9df9a 346 Gene3D G3DSA:3.40.630.10 21 328 1.7E-65 T 23-10-2018 STK_01900 d1fa16b83a32d97ba07b034daca9df9a 346 Gene3D G3DSA:3.30.70.360 157 257 1.7E-65 T 23-10-2018 STK_01900 d1fa16b83a32d97ba07b034daca9df9a 346 SUPERFAMILY SSF55031 157 248 1.94E-8 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain STK_01900 d1fa16b83a32d97ba07b034daca9df9a 346 Pfam PF07687 Peptidase dimerisation domain 157 246 5.8E-6 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain STK_01900 d1fa16b83a32d97ba07b034daca9df9a 346 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 89 123 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 STK_01900 d1fa16b83a32d97ba07b034daca9df9a 346 Pfam PF01546 Peptidase family M20/M25/M40 63 339 4.9E-29 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 STK_01900 d1fa16b83a32d97ba07b034daca9df9a 346 SUPERFAMILY SSF53187 9 342 3.71E-40 T 23-10-2018 STK_01900 d1fa16b83a32d97ba07b034daca9df9a 346 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 62 71 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 STK_14960 719bb0f29039ba605a8993358717096a 443 Pfam PF13522 Glutamine amidotransferase domain 68 180 2.1E-12 T 23-10-2018 STK_14960 719bb0f29039ba605a8993358717096a 443 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 7 425 1.2E-123 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 STK_14960 719bb0f29039ba605a8993358717096a 443 PIRSF PIRSF000485 3 440 1.4E-150 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 STK_14960 719bb0f29039ba605a8993358717096a 443 Pfam PF00156 Phosphoribosyl transferase domain 260 356 2.9E-7 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 STK_14960 719bb0f29039ba605a8993358717096a 443 Gene3D G3DSA:3.60.20.10 7 425 1.6E-133 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_14960 719bb0f29039ba605a8993358717096a 443 Gene3D G3DSA:3.40.50.2020 245 409 1.6E-133 T 23-10-2018 STK_14960 719bb0f29039ba605a8993358717096a 443 SUPERFAMILY SSF56235 7 227 6.43E-49 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_14960 719bb0f29039ba605a8993358717096a 443 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 6 424 42.235 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 STK_14960 719bb0f29039ba605a8993358717096a 443 SUPERFAMILY SSF53271 221 429 1.02E-64 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like STK_11807 6184fe050ab8497c250ea969c94112bb 191 SUPERFAMILY SSF52540 6 77 9.11E-9 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_11807 6184fe050ab8497c250ea969c94112bb 191 Gene3D G3DSA:1.10.8.60 24 103 4.6E-22 T 23-10-2018 STK_11807 6184fe050ab8497c250ea969c94112bb 191 Gene3D G3DSA:1.10.10.10 107 173 5.3E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_23170 93acb3d5674918e16d82e4a94bc4b4e6 738 SMART SM00490 286 367 2.3E-20 T 23-10-2018 IPR001650 Helicase, C-terminal STK_23170 93acb3d5674918e16d82e4a94bc4b4e6 738 SUPERFAMILY SSF52540 67 379 1.04E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_23170 93acb3d5674918e16d82e4a94bc4b4e6 738 SMART SM00487 52 247 5.0E-34 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain STK_23170 93acb3d5674918e16d82e4a94bc4b4e6 738 Gene3D G3DSA:3.40.50.300 34 231 4.8E-39 T 23-10-2018 STK_23170 93acb3d5674918e16d82e4a94bc4b4e6 738 Gene3D G3DSA:3.40.50.300 256 387 4.5E-28 T 23-10-2018 STK_23170 93acb3d5674918e16d82e4a94bc4b4e6 738 Pfam PF00270 DEAD/DEAH box helicase 58 218 1.9E-23 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 STK_23170 93acb3d5674918e16d82e4a94bc4b4e6 738 Pfam PF09369 Domain of unknown function (DUF1998) 622 694 7.9E-11 T 23-10-2018 IPR018973 DEAD/DEAH-box helicase, putative STK_23170 93acb3d5674918e16d82e4a94bc4b4e6 738 Pfam PF00271 Helicase conserved C-terminal domain 266 366 2.2E-17 T 23-10-2018 IPR001650 Helicase, C-terminal STK_21605 5efb67db60b8af16ede6a75523e43214 92 Pfam PF01022 Bacterial regulatory protein, arsR family 17 60 5.9E-11 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 STK_21605 5efb67db60b8af16ede6a75523e43214 92 SUPERFAMILY SSF46785 3 84 1.65E-19 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_21605 5efb67db60b8af16ede6a75523e43214 92 Gene3D G3DSA:1.10.10.10 5 91 1.3E-17 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_21605 5efb67db60b8af16ede6a75523e43214 92 SMART SM00418 8 84 3.3E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 STK_06000 ef73a1fa8ab2405392e60a2e1f0d70a9 168 Gene3D G3DSA:3.20.19.10 1 166 1.9E-56 T 23-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 STK_06000 ef73a1fa8ab2405392e60a2e1f0d70a9 168 Hamap MF_01032 Methanogen homoaconitase small subunit [hacB]. 3 162 35.493 T 23-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 STK_06000 ef73a1fa8ab2405392e60a2e1f0d70a9 168 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 5 159 6.7E-75 T 23-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 STK_06000 ef73a1fa8ab2405392e60a2e1f0d70a9 168 Pfam PF00694 Aconitase C-terminal domain 40 104 2.5E-21 T 23-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 STK_06000 ef73a1fa8ab2405392e60a2e1f0d70a9 168 SUPERFAMILY SSF52016 3 159 7.38E-46 T 23-10-2018 STK_23660 f0653141dc0899697e2ce32fcd4bb6d7 396 SUPERFAMILY SSF51604 107 372 2.1E-78 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily STK_23660 f0653141dc0899697e2ce32fcd4bb6d7 396 Gene3D G3DSA:3.20.20.120 112 357 1.9E-114 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily STK_23660 f0653141dc0899697e2ce32fcd4bb6d7 396 SUPERFAMILY SSF54826 4 124 6.91E-25 T 23-10-2018 STK_23660 f0653141dc0899697e2ce32fcd4bb6d7 396 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 9 119 1.4E-14 T 23-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain STK_23660 f0653141dc0899697e2ce32fcd4bb6d7 396 Pfam PF13378 Enolase C-terminal domain-like 143 365 3.2E-58 T 23-10-2018 IPR029065 Enolase C-terminal domain-like STK_23660 f0653141dc0899697e2ce32fcd4bb6d7 396 Gene3D G3DSA:3.30.390.10 26 368 1.9E-114 T 23-10-2018 IPR029017 Enolase-like, N-terminal STK_23660 f0653141dc0899697e2ce32fcd4bb6d7 396 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 94 119 - T 23-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 STK_23660 f0653141dc0899697e2ce32fcd4bb6d7 396 SMART SM00922 140 245 6.1E-23 T 23-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal STK_02800 6b8fbce1d0a751c062f080c55f119b96 147 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 36.367 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 STK_02800 6b8fbce1d0a751c062f080c55f119b96 147 Gene3D G3DSA:3.30.70.141 1 146 6.8E-63 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 STK_02800 6b8fbce1d0a751c062f080c55f119b96 147 SMART SM00562 3 140 1.5E-84 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 STK_02800 6b8fbce1d0a751c062f080c55f119b96 147 SUPERFAMILY SSF54919 1 141 2.49E-59 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 STK_02800 6b8fbce1d0a751c062f080c55f119b96 147 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 23-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 STK_02800 6b8fbce1d0a751c062f080c55f119b96 147 Pfam PF00334 Nucleoside diphosphate kinase 4 137 5.8E-59 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 STK_02800 6b8fbce1d0a751c062f080c55f119b96 147 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 6.7E-44 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 STK_02800 6b8fbce1d0a751c062f080c55f119b96 147 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 6.7E-44 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 STK_02800 6b8fbce1d0a751c062f080c55f119b96 147 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 6.7E-44 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 STK_02800 6b8fbce1d0a751c062f080c55f119b96 147 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 6.7E-44 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 STK_02800 6b8fbce1d0a751c062f080c55f119b96 147 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 6.7E-44 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 STK_05540 371c4bba88319f3ca105dfd183f0d411 140 SUPERFAMILY SSF54593 2 140 5.64E-35 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase STK_05540 371c4bba88319f3ca105dfd183f0d411 140 Gene3D G3DSA:3.10.180.10 1 137 7.1E-41 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase STK_05540 371c4bba88319f3ca105dfd183f0d411 140 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 6 137 4.9E-44 T 23-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 STK_05540 371c4bba88319f3ca105dfd183f0d411 140 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 122 1.5E-24 T 23-10-2018 STK_16640 ff5c8418a557f2c09312587386aef51c 466 Gene3D G3DSA:2.60.40.1190 342 415 2.3E-10 T 23-10-2018 STK_16640 ff5c8418a557f2c09312587386aef51c 466 Pfam PF09459 Ethylbenzene dehydrogenase 56 403 1.9E-32 T 23-10-2018 IPR019020 Cytochrome c-552/DMSO reductase-like, haem-binding domain GO:0020037 STK_16640 ff5c8418a557f2c09312587386aef51c 466 SMART SM00887 55 403 3.1E-103 T 23-10-2018 IPR019020 Cytochrome c-552/DMSO reductase-like, haem-binding domain GO:0020037 STK_16640 ff5c8418a557f2c09312587386aef51c 466 TIGRFAM TIGR03154 sulfolob_CbsA: cytochrome b558/566, subunit A 2 466 6.9E-304 T 23-10-2018 IPR017572 Cytochrome b558/566, subunit A GO:0005886|GO:0016021|GO:0020037|GO:0022900 STK_03105 ce3c7942a21a5121f839999792a7fc1d 58 Pfam PF03911 Sec61beta family 15 54 4.1E-15 T 23-10-2018 IPR016482 Protein transport protein SecG/Sec61-beta/Sbh Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 STK_03105 ce3c7942a21a5121f839999792a7fc1d 58 Hamap MF_00751 Preprotein translocase subunit SecG [secG]. 3 55 16.014 T 23-10-2018 IPR023531 Preprotein translocase subunit SecG STK_03160 fe6c08a77b498344294341c6f41165df 100 Pfam PF07935 ORF D-335-like protein 7 74 8.3E-31 T 23-10-2018 IPR012922 ORF D-335-like STK_08805 d273c32d1554fbb1cf461f7bb785997a 70 SUPERFAMILY SSF64307 1 70 1.11E-12 T 23-10-2018 IPR036868 TusA-like domain superfamily STK_08805 d273c32d1554fbb1cf461f7bb785997a 70 Pfam PF01206 Sulfurtransferase TusA 2 70 3.6E-13 T 23-10-2018 IPR001455 TusA-like domain STK_08805 d273c32d1554fbb1cf461f7bb785997a 70 Gene3D G3DSA:3.30.110.40 1 70 8.0E-7 T 23-10-2018 IPR036868 TusA-like domain superfamily STK_19030 5b8fd68bb5b531e656bfa72fb94f42e1 359 Gene3D G3DSA:3.40.630.10 121 330 3.1E-12 T 23-10-2018 STK_19030 5b8fd68bb5b531e656bfa72fb94f42e1 359 SUPERFAMILY SSF53187 134 294 2.02E-13 T 23-10-2018 STK_07570 86e922f09e2006d94fdb17798b4e7a8b 136 Gene3D G3DSA:1.10.10.10 6 126 7.1E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_07570 86e922f09e2006d94fdb17798b4e7a8b 136 Pfam PF03551 Transcriptional regulator PadR-like family 17 85 3.5E-18 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal STK_07570 86e922f09e2006d94fdb17798b4e7a8b 136 SUPERFAMILY SSF46785 13 124 1.08E-25 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_10600 0ab599f4e0080c901c72ebd2c33fa02f 111 SUPERFAMILY SSF46785 49 109 2.81E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_10600 0ab599f4e0080c901c72ebd2c33fa02f 111 Pfam PF09339 IclR helix-turn-helix domain 59 96 2.5E-10 T 23-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 STK_10600 0ab599f4e0080c901c72ebd2c33fa02f 111 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 49 65 2.1E-5 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_10600 0ab599f4e0080c901c72ebd2c33fa02f 111 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 75 94 2.1E-5 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_10600 0ab599f4e0080c901c72ebd2c33fa02f 111 Gene3D G3DSA:1.10.10.10 48 111 5.5E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_18240 7c8fb4d63677f6fda9bcbc071efb9bc8 333 SUPERFAMILY SSF63965 135 328 3.14E-51 T 23-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 STK_18240 7c8fb4d63677f6fda9bcbc071efb9bc8 333 Gene3D G3DSA:3.40.50.1400 1 127 2.6E-13 T 23-10-2018 STK_18240 7c8fb4d63677f6fda9bcbc071efb9bc8 333 Gene3D G3DSA:3.40.50.10230 128 328 2.1E-53 T 23-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 STK_18240 7c8fb4d63677f6fda9bcbc071efb9bc8 333 Pfam PF01903 CbiX 11 121 6.8E-22 T 23-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 STK_18240 7c8fb4d63677f6fda9bcbc071efb9bc8 333 Pfam PF02570 Precorrin-8X methylmutase 142 327 2.4E-49 T 23-10-2018 IPR003722 Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC GO:0009236|GO:0016993 STK_18240 7c8fb4d63677f6fda9bcbc071efb9bc8 333 SUPERFAMILY SSF53800 3 126 3.01E-18 T 23-10-2018 STK_20630 3bf738cf7c45d15b4e3f54e95dcc19cf 225 SUPERFAMILY SSF52313 29 212 2.35E-58 T 23-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily STK_20630 3bf738cf7c45d15b4e3f54e95dcc19cf 225 TIGRFAM TIGR01012 uS2_euk_arch: ribosomal protein uS2 29 222 4.8E-81 T 23-10-2018 IPR005707 Ribosomal protein S2, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_20630 3bf738cf7c45d15b4e3f54e95dcc19cf 225 Gene3D G3DSA:3.40.50.10490 32 225 7.4E-65 T 23-10-2018 STK_20630 3bf738cf7c45d15b4e3f54e95dcc19cf 225 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 33 44 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 STK_20630 3bf738cf7c45d15b4e3f54e95dcc19cf 225 PRINTS PR00395 Ribosomal protein S2 signature 33 51 4.7E-24 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_20630 3bf738cf7c45d15b4e3f54e95dcc19cf 225 PRINTS PR00395 Ribosomal protein S2 signature 153 164 4.7E-24 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_20630 3bf738cf7c45d15b4e3f54e95dcc19cf 225 PRINTS PR00395 Ribosomal protein S2 signature 174 188 4.7E-24 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_20630 3bf738cf7c45d15b4e3f54e95dcc19cf 225 PRINTS PR00395 Ribosomal protein S2 signature 111 128 4.7E-24 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_20630 3bf738cf7c45d15b4e3f54e95dcc19cf 225 PRINTS PR00395 Ribosomal protein S2 signature 136 153 4.7E-24 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_20630 3bf738cf7c45d15b4e3f54e95dcc19cf 225 PRINTS PR00395 Ribosomal protein S2 signature 63 72 4.7E-24 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_20630 3bf738cf7c45d15b4e3f54e95dcc19cf 225 Pfam PF00318 Ribosomal protein S2 37 128 2.4E-8 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_20630 3bf738cf7c45d15b4e3f54e95dcc19cf 225 Pfam PF00318 Ribosomal protein S2 134 200 5.1E-16 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_20630 3bf738cf7c45d15b4e3f54e95dcc19cf 225 Hamap MF_00291_A 30S ribosomal protein S2 [rpsB]. 25 223 47.723 T 23-10-2018 IPR023454 Ribosomal protein S2, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_05240 3f60a2fd9454baeb3e7760f7a4304cc9 172 Gene3D G3DSA:3.90.80.10 1 170 5.0E-71 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 STK_05240 3f60a2fd9454baeb3e7760f7a4304cc9 172 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 62 68 - T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 STK_05240 3f60a2fd9454baeb3e7760f7a4304cc9 172 Pfam PF00719 Inorganic pyrophosphatase 15 169 4.6E-57 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 STK_05240 3f60a2fd9454baeb3e7760f7a4304cc9 172 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 11 170 38.658 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 STK_05240 3f60a2fd9454baeb3e7760f7a4304cc9 172 SUPERFAMILY SSF50324 3 169 5.89E-67 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 STK_14920 ae75be999f1ee0fda3b29fdf29122ec0 113 Gene3D G3DSA:2.40.50.140 1 113 2.7E-35 T 23-10-2018 STK_14920 ae75be999f1ee0fda3b29fdf29122ec0 113 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 2 113 8.5E-40 T 23-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 STK_14920 ae75be999f1ee0fda3b29fdf29122ec0 113 Pfam PF01588 Putative tRNA binding domain 14 111 6.6E-29 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 STK_14920 ae75be999f1ee0fda3b29fdf29122ec0 113 SUPERFAMILY SSF50249 3 112 3.67E-30 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_22790 77471b48220b41c66c193fb877e6e310 100 SUPERFAMILY SSF50022 5 98 2.23E-23 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 STK_22790 77471b48220b41c66c193fb877e6e310 100 Pfam PF00355 Rieske [2Fe-2S] domain 4 87 9.5E-16 T 23-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 STK_22790 77471b48220b41c66c193fb877e6e310 100 Gene3D G3DSA:2.102.10.10 2 100 2.5E-23 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 STK_04234 bd37a3d27408f4448dff4445d99d330a 77 Gene3D G3DSA:2.30.30.210 1 77 1.4E-20 T 23-10-2018 IPR036980 Ribonuclease P/MRP, subunit p29 superfamily GO:0003723|GO:0004540|GO:0008033|GO:0030677 Reactome: R-HSA-6784531 STK_04234 bd37a3d27408f4448dff4445d99d330a 77 SUPERFAMILY SSF101744 2 76 1.03E-20 T 23-10-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 STK_04234 bd37a3d27408f4448dff4445d99d330a 77 Hamap MF_00754 Ribonuclease P protein component 1 [rnp1]. 1 77 15.408 T 23-10-2018 IPR023538 Ribonuclease P protein component 1 GO:0001682|GO:0004526 STK_04234 bd37a3d27408f4448dff4445d99d330a 77 SMART SM00538 1 75 3.1E-4 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 STK_04234 bd37a3d27408f4448dff4445d99d330a 77 Pfam PF01868 Domain of unknown function UPF0086 2 75 3.7E-16 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 STK_22810 383f7b2b1f38fa2c4f0edca40cc9408b 264 Pfam PF13192 Thioredoxin domain 1 74 1.4E-8 T 23-10-2018 IPR012336 Thioredoxin-like fold STK_22810 383f7b2b1f38fa2c4f0edca40cc9408b 264 Gene3D G3DSA:3.40.30.10 1 75 4.9E-7 T 23-10-2018 STK_22810 383f7b2b1f38fa2c4f0edca40cc9408b 264 SUPERFAMILY SSF52833 2 74 5.3E-12 T 23-10-2018 IPR036249 Thioredoxin-like superfamily STK_05770 b43264779423d8338b769f174287193f 157 Gene3D G3DSA:3.90.79.10 2 144 5.6E-28 T 23-10-2018 STK_05770 b43264779423d8338b769f174287193f 157 SUPERFAMILY SSF55811 6 141 1.03E-25 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 STK_05770 b43264779423d8338b769f174287193f 157 Pfam PF00293 NUDIX domain 6 118 3.6E-14 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 STK_03890 2a44466417aefbd65c074a50cb32acdf 437 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 5 432 1.6E-118 T 23-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 STK_03890 2a44466417aefbd65c074a50cb32acdf 437 Gene3D G3DSA:3.40.50.880 250 417 2.9E-5 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_03890 2a44466417aefbd65c074a50cb32acdf 437 SUPERFAMILY SSF52317 246 431 1.24E-22 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_03890 2a44466417aefbd65c074a50cb32acdf 437 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 183 1.7E-10 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain STK_03890 2a44466417aefbd65c074a50cb32acdf 437 Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. 3 432 41.865 T 23-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 STK_03890 2a44466417aefbd65c074a50cb32acdf 437 Gene3D G3DSA:3.40.50.300 42 181 1.5E-13 T 23-10-2018 STK_03890 2a44466417aefbd65c074a50cb32acdf 437 SUPERFAMILY SSF52540 1 188 3.72E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_03890 2a44466417aefbd65c074a50cb32acdf 437 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 245 431 1.4E-39 T 23-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 STK_02000 89f1c2b107e2a4196de08deb7d107e6c 289 SUPERFAMILY SSF53613 31 271 7.37E-20 T 23-10-2018 IPR029056 Ribokinase-like STK_02000 89f1c2b107e2a4196de08deb7d107e6c 289 Gene3D G3DSA:3.40.1190.20 31 284 8.8E-42 T 23-10-2018 IPR029056 Ribokinase-like STK_20850 2cf777fdc2d79c710f85c0b821126219 274 SUPERFAMILY SSF103481 39 129 1.96E-12 T 23-10-2018 STK_20850 2cf777fdc2d79c710f85c0b821126219 274 Pfam PF00892 EamA-like transporter family 4 129 3.7E-15 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 STK_20850 2cf777fdc2d79c710f85c0b821126219 274 Pfam PF00892 EamA-like transporter family 138 267 4.6E-21 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 STK_20850 2cf777fdc2d79c710f85c0b821126219 274 SUPERFAMILY SSF103481 172 270 1.44E-13 T 23-10-2018 STK_16920 20581c650793bba0be93b083a6b8f01f 1177 Pfam PF00082 Subtilase family 294 479 4.1E-6 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 STK_16920 20581c650793bba0be93b083a6b8f01f 1177 SUPERFAMILY SSF54897 29 164 3.74E-9 T 23-10-2018 STK_16920 20581c650793bba0be93b083a6b8f01f 1177 Pfam PF09286 Pro-kumamolisin, activation domain 32 132 1.7E-11 T 23-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 STK_16920 20581c650793bba0be93b083a6b8f01f 1177 PIRSF PIRSF032623 1 1174 0.0 T 23-10-2018 IPR017001 Peptidase S53, physarolisin II, archaeal-type STK_16920 20581c650793bba0be93b083a6b8f01f 1177 SMART SM00944 17 150 6.5E-26 T 23-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 STK_16920 20581c650793bba0be93b083a6b8f01f 1177 SUPERFAMILY SSF52743 183 536 2.36E-61 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 STK_16920 20581c650793bba0be93b083a6b8f01f 1177 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 459 469 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site STK_16920 20581c650793bba0be93b083a6b8f01f 1177 Gene3D G3DSA:3.40.50.200 178 540 3.4E-77 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 STK_03110 fe79bdd4e8741026fc302b2ae7dfd396 167 Hamap MF_01116 Probable ribosome biogenesis protein . 1 161 31.6 T 23-10-2018 IPR022968 Ribosome biogenesis protein Reactome: R-HSA-6790901 STK_03110 fe79bdd4e8741026fc302b2ae7dfd396 167 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 1 35 3.7E-13 T 23-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain STK_03110 fe79bdd4e8741026fc302b2ae7dfd396 167 Pfam PF04034 Ribosome biogenesis protein, C-terminal 36 159 6.7E-40 T 23-10-2018 IPR007177 Ribosome biogenesis protein, C-terminal Reactome: R-HSA-6790901 STK_03110 fe79bdd4e8741026fc302b2ae7dfd396 167 ProDom PD016638 UPF0293 SIMILAR RNASE YOR006C RNA COMPONENT SACCHAROMYCES P RIKEN CERVISIAE 26 158 5.0E-70 T 23-10-2018 IPR007177 Ribosome biogenesis protein, C-terminal Reactome: R-HSA-6790901 STK_04400 630b9b0c7e8fe7e71a11af9e44a2ce94 125 TIGRFAM TIGR02338 gimC_beta: prefoldin, beta subunit 5 114 4.6E-40 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 STK_04400 630b9b0c7e8fe7e71a11af9e44a2ce94 125 SUPERFAMILY SSF46579 7 112 2.88E-23 T 23-10-2018 STK_04400 630b9b0c7e8fe7e71a11af9e44a2ce94 125 Hamap MF_00307 Prefoldin subunit beta [pfdB]. 1 125 46.968 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 STK_04400 630b9b0c7e8fe7e71a11af9e44a2ce94 125 Gene3D G3DSA:1.10.287.370 2 116 8.0E-33 T 23-10-2018 IPR009053 Prefoldin STK_04400 630b9b0c7e8fe7e71a11af9e44a2ce94 125 Pfam PF01920 Prefoldin subunit 10 114 1.2E-23 T 23-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 STK_12450 9a680645fbae1d36e55e2660e4441831 306 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 4 306 71.519 T 23-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 STK_12450 9a680645fbae1d36e55e2660e4441831 306 Gene3D G3DSA:3.40.50.1370 135 302 3.1E-111 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 STK_12450 9a680645fbae1d36e55e2660e4441831 306 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 5 306 5.2E-113 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 STK_12450 9a680645fbae1d36e55e2660e4441831 306 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 50 57 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 STK_12450 9a680645fbae1d36e55e2660e4441831 306 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 5 145 1.2E-46 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 STK_12450 9a680645fbae1d36e55e2660e4441831 306 SUPERFAMILY SSF53671 2 306 1.62E-95 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 STK_12450 9a680645fbae1d36e55e2660e4441831 306 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 50 69 1.7E-28 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 STK_12450 9a680645fbae1d36e55e2660e4441831 306 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 259 268 1.7E-28 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 STK_12450 9a680645fbae1d36e55e2660e4441831 306 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 132 143 1.7E-28 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 STK_12450 9a680645fbae1d36e55e2660e4441831 306 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 271 294 1.7E-28 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 STK_12450 9a680645fbae1d36e55e2660e4441831 306 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 153 304 2.5E-51 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 STK_12450 9a680645fbae1d36e55e2660e4441831 306 PRINTS PR00102 Ornithine carbamoyltransferase signature 285 296 1.0E-26 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 STK_12450 9a680645fbae1d36e55e2660e4441831 306 PRINTS PR00102 Ornithine carbamoyltransferase signature 223 233 1.0E-26 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 STK_12450 9a680645fbae1d36e55e2660e4441831 306 PRINTS PR00102 Ornithine carbamoyltransferase signature 81 94 1.0E-26 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 STK_12450 9a680645fbae1d36e55e2660e4441831 306 PRINTS PR00102 Ornithine carbamoyltransferase signature 121 135 1.0E-26 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 STK_12450 9a680645fbae1d36e55e2660e4441831 306 PRINTS PR00102 Ornithine carbamoyltransferase signature 48 62 1.0E-26 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 STK_12450 9a680645fbae1d36e55e2660e4441831 306 Gene3D G3DSA:3.40.50.1370 5 134 3.1E-111 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 STK_07085 7898da987cf375680cb539cb65da5b45 77 ProSitePatterns PS01104 Ribosomal protein L13e signature. 21 35 - T 23-10-2018 IPR018256 Ribosomal protein L13e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_07085 7898da987cf375680cb539cb65da5b45 77 Pfam PF01294 Ribosomal protein L13e 2 70 3.4E-12 T 23-10-2018 IPR001380 Ribosomal protein L13e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_07085 7898da987cf375680cb539cb65da5b45 77 Hamap MF_00499 50S ribosomal protein L13e [rpl13e]. 2 75 17.334 T 23-10-2018 IPR001380 Ribosomal protein L13e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_23000 d30bf59e3f3caf9ccb0010ad3a840773 627 Gene3D G3DSA:3.40.50.970 216 426 1.3E-73 T 23-10-2018 STK_23000 d30bf59e3f3caf9ccb0010ad3a840773 627 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 210 1.9E-32 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 STK_23000 d30bf59e3f3caf9ccb0010ad3a840773 627 SUPERFAMILY SSF52922 507 616 9.26E-13 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 STK_23000 d30bf59e3f3caf9ccb0010ad3a840773 627 Gene3D G3DSA:3.40.50.920 503 616 2.1E-20 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 STK_23000 d30bf59e3f3caf9ccb0010ad3a840773 627 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 241 489 6.2E-71 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 STK_23000 d30bf59e3f3caf9ccb0010ad3a840773 627 SUPERFAMILY SSF53323 2 249 7.85E-14 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 STK_23000 d30bf59e3f3caf9ccb0010ad3a840773 627 SUPERFAMILY SSF52518 228 496 2.1E-62 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold STK_23000 d30bf59e3f3caf9ccb0010ad3a840773 627 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 97 609 2.2E-161 T 23-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 STK_03010 939cbd5249fb834863911e2bf8f7f223 275 PIRSF PIRSF006779 2 266 4.1E-99 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase STK_03010 939cbd5249fb834863911e2bf8f7f223 275 Gene3D G3DSA:3.40.50.10790 5 161 1.6E-55 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal STK_03010 939cbd5249fb834863911e2bf8f7f223 275 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 6 261 4.4E-72 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase STK_03010 939cbd5249fb834863911e2bf8f7f223 275 SUPERFAMILY SSF101852 178 264 9.81E-22 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal STK_03010 939cbd5249fb834863911e2bf8f7f223 275 Gene3D G3DSA:2.40.30.90 168 266 1.5E-18 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal STK_03010 939cbd5249fb834863911e2bf8f7f223 275 SUPERFAMILY SSF102522 4 164 8.63E-59 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal STK_23320 69cb317747e9caf3dc1554aec6ab01ce 394 Pfam PF13641 Glycosyltransferase like family 2 42 270 2.8E-39 T 23-10-2018 STK_23320 69cb317747e9caf3dc1554aec6ab01ce 394 Gene3D G3DSA:3.90.550.10 35 254 3.6E-49 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_23320 69cb317747e9caf3dc1554aec6ab01ce 394 SUPERFAMILY SSF53448 40 308 2.06E-58 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_05950 e8e2e65a93fe4e4be55aa6620f8e1f46 240 SMART SM00382 11 193 3.4E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_05950 e8e2e65a93fe4e4be55aa6620f8e1f46 240 ProSitePatterns PS00211 ABC transporters family signature. 114 128 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 STK_05950 e8e2e65a93fe4e4be55aa6620f8e1f46 240 Pfam PF00005 ABC transporter 3 141 2.0E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_05950 e8e2e65a93fe4e4be55aa6620f8e1f46 240 Gene3D G3DSA:3.40.50.300 1 240 3.5E-54 T 23-10-2018 STK_05950 e8e2e65a93fe4e4be55aa6620f8e1f46 240 SUPERFAMILY SSF52540 2 222 4.35E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_08130 22b77a4040691f3361d7f0b44d44d0bd 273 SMART SM00116 10 56 1.1E-6 T 23-10-2018 IPR000644 CBS domain STK_08130 22b77a4040691f3361d7f0b44d44d0bd 273 SMART SM00116 146 194 2.4E-10 T 23-10-2018 IPR000644 CBS domain STK_08130 22b77a4040691f3361d7f0b44d44d0bd 273 SMART SM00116 217 265 1.4E-7 T 23-10-2018 IPR000644 CBS domain STK_08130 22b77a4040691f3361d7f0b44d44d0bd 273 SMART SM00116 83 131 1.5E-9 T 23-10-2018 IPR000644 CBS domain STK_08130 22b77a4040691f3361d7f0b44d44d0bd 273 Gene3D G3DSA:3.10.580.10 134 272 1.6E-42 T 23-10-2018 STK_08130 22b77a4040691f3361d7f0b44d44d0bd 273 Pfam PF00571 CBS domain 210 265 1.0E-9 T 23-10-2018 IPR000644 CBS domain STK_08130 22b77a4040691f3361d7f0b44d44d0bd 273 Pfam PF00571 CBS domain 77 127 4.6E-12 T 23-10-2018 IPR000644 CBS domain STK_08130 22b77a4040691f3361d7f0b44d44d0bd 273 Pfam PF00571 CBS domain 3 56 1.3E-10 T 23-10-2018 IPR000644 CBS domain STK_08130 22b77a4040691f3361d7f0b44d44d0bd 273 Pfam PF00571 CBS domain 139 188 4.3E-12 T 23-10-2018 IPR000644 CBS domain STK_08130 22b77a4040691f3361d7f0b44d44d0bd 273 SUPERFAMILY SSF54631 199 268 7.07E-13 T 23-10-2018 STK_08130 22b77a4040691f3361d7f0b44d44d0bd 273 SUPERFAMILY SSF54631 1 58 1.2E-9 T 23-10-2018 STK_08130 22b77a4040691f3361d7f0b44d44d0bd 273 SUPERFAMILY SSF54631 76 197 7.59E-31 T 23-10-2018 STK_08130 22b77a4040691f3361d7f0b44d44d0bd 273 Gene3D G3DSA:3.10.580.10 1 133 2.0E-33 T 23-10-2018 STK_09540 802ee144b62f90f460ee602d4536bf4f 902 Gene3D G3DSA:3.30.2250.10 68 225 4.7E-86 T 23-10-2018 STK_09540 802ee144b62f90f460ee602d4536bf4f 902 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 9 150 4.2E-13 T 23-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal STK_09540 802ee144b62f90f460ee602d4536bf4f 902 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 541 787 8.7E-38 T 23-10-2018 IPR006500 DNA primase, phage/plasmid STK_09540 802ee144b62f90f460ee602d4536bf4f 902 SUPERFAMILY SSF46785 759 808 1.36E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_09540 802ee144b62f90f460ee602d4536bf4f 902 Gene3D G3DSA:3.40.50.300 532 717 3.9E-17 T 23-10-2018 STK_09540 802ee144b62f90f460ee602d4536bf4f 902 SUPERFAMILY SSF52540 515 691 5.04E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_09540 802ee144b62f90f460ee602d4536bf4f 902 SUPERFAMILY SSF56747 2 212 1.44E-74 T 23-10-2018 STK_09540 802ee144b62f90f460ee602d4536bf4f 902 SMART SM00885 373 536 2.6E-13 T 23-10-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal STK_09540 802ee144b62f90f460ee602d4536bf4f 902 Gene3D G3DSA:1.10.1200.130 1 67 4.1E-36 T 23-10-2018 STK_09540 802ee144b62f90f460ee602d4536bf4f 902 Pfam PF08706 D5 N terminal like 381 542 2.0E-15 T 23-10-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal STK_09540 802ee144b62f90f460ee602d4536bf4f 902 Pfam PF13010 Primase helical domain 215 350 2.5E-81 T 23-10-2018 IPR024966 Primase helical domain STK_09540 802ee144b62f90f460ee602d4536bf4f 902 SMART SM00943 8 211 2.7E-46 T 23-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal STK_09540 802ee144b62f90f460ee602d4536bf4f 902 Gene3D G3DSA:1.10.1240.50 241 351 7.7E-38 T 23-10-2018 STK_03030 fbb48c2c72157d901cb373540f0efe53 307 SUPERFAMILY SSF54637 5 138 4.64E-25 T 23-10-2018 IPR029069 HotDog domain superfamily STK_03030 fbb48c2c72157d901cb373540f0efe53 307 SUPERFAMILY SSF54637 159 301 3.5E-33 T 23-10-2018 IPR029069 HotDog domain superfamily STK_03030 fbb48c2c72157d901cb373540f0efe53 307 Gene3D G3DSA:3.10.129.10 156 304 1.5E-34 T 23-10-2018 STK_03030 fbb48c2c72157d901cb373540f0efe53 307 Gene3D G3DSA:3.10.129.10 2 146 1.2E-24 T 23-10-2018 STK_03030 fbb48c2c72157d901cb373540f0efe53 307 Pfam PF03061 Thioesterase superfamily 18 90 6.8E-7 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 STK_03030 fbb48c2c72157d901cb373540f0efe53 307 Pfam PF03061 Thioesterase superfamily 169 239 1.2E-12 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 STK_17760 0f2c2a82b1c78759425a596d9a8da105 602 SUPERFAMILY SSF52467 477 594 8.88E-44 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily STK_17760 0f2c2a82b1c78759425a596d9a8da105 602 SUPERFAMILY SSF52402 1 244 7.67E-72 T 23-10-2018 STK_17760 0f2c2a82b1c78759425a596d9a8da105 602 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 477 557 4.7E-33 T 23-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 STK_17760 0f2c2a82b1c78759425a596d9a8da105 602 SMART SM00893 22 213 9.5E-57 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 STK_17760 0f2c2a82b1c78759425a596d9a8da105 602 SMART SM00893 280 463 2.6E-31 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 STK_17760 0f2c2a82b1c78759425a596d9a8da105 602 Gene3D G3DSA:3.40.50.1220 473 600 7.9E-51 T 23-10-2018 STK_17760 0f2c2a82b1c78759425a596d9a8da105 602 Gene3D G3DSA:3.40.50.620 1 263 8.8E-87 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_17760 0f2c2a82b1c78759425a596d9a8da105 602 Pfam PF01012 Electron transfer flavoprotein domain 280 456 1.0E-35 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 STK_17760 0f2c2a82b1c78759425a596d9a8da105 602 Pfam PF01012 Electron transfer flavoprotein domain 24 208 1.2E-44 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 STK_17760 0f2c2a82b1c78759425a596d9a8da105 602 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 539 565 - T 23-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 STK_17760 0f2c2a82b1c78759425a596d9a8da105 602 SUPERFAMILY SSF52402 280 469 1.53E-45 T 23-10-2018 STK_17760 0f2c2a82b1c78759425a596d9a8da105 602 Gene3D G3DSA:3.40.50.620 277 472 4.1E-56 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_09830 02ace6c49b7511784c0f99f1d660a63e 249 Pfam PF13432 Tetratricopeptide repeat 7 59 4.3E-6 T 23-10-2018 STK_09830 02ace6c49b7511784c0f99f1d660a63e 249 SMART SM00028 119 152 480.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 STK_09830 02ace6c49b7511784c0f99f1d660a63e 249 SMART SM00028 219 249 50.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 STK_09830 02ace6c49b7511784c0f99f1d660a63e 249 SMART SM00028 185 218 4.1E-7 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 STK_09830 02ace6c49b7511784c0f99f1d660a63e 249 SMART SM00028 33 66 58.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 STK_09830 02ace6c49b7511784c0f99f1d660a63e 249 SMART SM00028 153 184 36.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 STK_09830 02ace6c49b7511784c0f99f1d660a63e 249 Gene3D G3DSA:1.25.40.10 62 169 4.6E-8 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 STK_09830 02ace6c49b7511784c0f99f1d660a63e 249 Gene3D G3DSA:1.25.40.10 1 61 1.7E-10 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 STK_09830 02ace6c49b7511784c0f99f1d660a63e 249 SUPERFAMILY SSF48452 10 241 4.09E-27 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 STK_09830 02ace6c49b7511784c0f99f1d660a63e 249 Gene3D G3DSA:1.25.40.10 170 249 2.2E-20 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 STK_09830 02ace6c49b7511784c0f99f1d660a63e 249 Pfam PF13414 TPR repeat 199 233 8.6E-9 T 23-10-2018 STK_25720 3e3a57739f6a944647ba442417a1489c 392 Gene3D G3DSA:3.20.20.120 111 356 2.5E-114 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily STK_25720 3e3a57739f6a944647ba442417a1489c 392 Gene3D G3DSA:3.30.390.10 25 367 2.5E-114 T 23-10-2018 IPR029017 Enolase-like, N-terminal STK_25720 3e3a57739f6a944647ba442417a1489c 392 Pfam PF13378 Enolase C-terminal domain-like 142 364 1.5E-57 T 23-10-2018 IPR029065 Enolase C-terminal domain-like STK_25720 3e3a57739f6a944647ba442417a1489c 392 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 25 118 3.1E-10 T 23-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain STK_25720 3e3a57739f6a944647ba442417a1489c 392 SMART SM00922 139 244 1.9E-22 T 23-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal STK_25720 3e3a57739f6a944647ba442417a1489c 392 SUPERFAMILY SSF54826 3 123 9.09E-23 T 23-10-2018 STK_25720 3e3a57739f6a944647ba442417a1489c 392 SUPERFAMILY SSF51604 106 372 7.47E-80 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily STK_11250 7d20524284e84a4bb56ec8c174db33a5 125 Pfam PF01850 PIN domain 3 113 1.8E-14 T 23-10-2018 IPR002716 PIN domain STK_11250 7d20524284e84a4bb56ec8c174db33a5 125 Gene3D G3DSA:3.40.50.1010 1 124 1.0E-25 T 23-10-2018 STK_11250 7d20524284e84a4bb56ec8c174db33a5 125 SUPERFAMILY SSF88723 1 115 1.26E-24 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_26390 050186157f97aa9f1d3cbfc429df25e6 498 SMART SM00490 269 345 4.1E-8 T 23-10-2018 IPR001650 Helicase, C-terminal STK_26390 050186157f97aa9f1d3cbfc429df25e6 498 Gene3D G3DSA:3.40.50.300 227 375 2.0E-19 T 23-10-2018 STK_26390 050186157f97aa9f1d3cbfc429df25e6 498 SMART SM00487 25 231 3.4E-11 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain STK_26390 050186157f97aa9f1d3cbfc429df25e6 498 Pfam PF00271 Helicase conserved C-terminal domain 244 345 4.4E-9 T 23-10-2018 IPR001650 Helicase, C-terminal STK_26390 050186157f97aa9f1d3cbfc429df25e6 498 Pfam PF00270 DEAD/DEAH box helicase 35 210 1.9E-9 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 STK_26390 050186157f97aa9f1d3cbfc429df25e6 498 Gene3D G3DSA:3.40.50.300 22 213 7.0E-16 T 23-10-2018 STK_26390 050186157f97aa9f1d3cbfc429df25e6 498 SUPERFAMILY SSF52540 40 355 1.71E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_26390 050186157f97aa9f1d3cbfc429df25e6 498 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 46 348 3.8E-60 T 23-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core STK_20760 ed2816ea74b4c4eddddfa9ad66ce8672 781 Gene3D G3DSA:3.30.342.10 8 395 3.1E-81 T 23-10-2018 STK_20760 ed2816ea74b4c4eddddfa9ad66ce8672 781 SUPERFAMILY SSF56672 379 768 1.06E-121 T 23-10-2018 STK_20760 ed2816ea74b4c4eddddfa9ad66ce8672 781 SUPERFAMILY SSF53098 4 399 4.24E-77 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily STK_20760 ed2816ea74b4c4eddddfa9ad66ce8672 781 Pfam PF00136 DNA polymerase family B 364 759 1.4E-75 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 STK_20760 ed2816ea74b4c4eddddfa9ad66ce8672 781 Gene3D G3DSA:1.10.132.60 621 780 1.8E-47 T 23-10-2018 STK_20760 ed2816ea74b4c4eddddfa9ad66ce8672 781 Gene3D G3DSA:3.30.420.10 142 377 3.1E-81 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 STK_20760 ed2816ea74b4c4eddddfa9ad66ce8672 781 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 219 759 2.8E-89 T 23-10-2018 STK_20760 ed2816ea74b4c4eddddfa9ad66ce8672 781 Gene3D G3DSA:1.10.287.690 472 523 3.4E-20 T 23-10-2018 STK_20760 ed2816ea74b4c4eddddfa9ad66ce8672 781 ProSitePatterns PS00116 DNA polymerase family B signature. 561 569 - T 23-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 STK_20760 ed2816ea74b4c4eddddfa9ad66ce8672 781 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 507 519 1.6E-11 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 STK_20760 ed2816ea74b4c4eddddfa9ad66ce8672 781 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 425 438 1.6E-11 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 STK_20760 ed2816ea74b4c4eddddfa9ad66ce8672 781 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 559 567 1.6E-11 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 STK_20760 ed2816ea74b4c4eddddfa9ad66ce8672 781 Pfam PF03104 DNA polymerase family B, exonuclease domain 27 293 2.0E-44 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 STK_20760 ed2816ea74b4c4eddddfa9ad66ce8672 781 SMART SM00486 170 573 2.0E-120 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 STK_00590 107d724647161a3eb7d88c170592625d 462 SUPERFAMILY SSF75011 37 400 7.19E-22 T 23-10-2018 STK_00590 107d724647161a3eb7d88c170592625d 462 Pfam PF05694 56kDa selenium binding protein (SBP56) 7 460 1.9E-205 T 23-10-2018 IPR008826 Selenium-binding protein GO:0008430 STK_13770 9c6a84b89d3fe6494f58103ff84541fc 348 SUPERFAMILY SSF109755 131 294 1.7E-10 T 23-10-2018 STK_13770 9c6a84b89d3fe6494f58103ff84541fc 348 Pfam PF01895 PhoU domain 145 234 7.6E-5 T 23-10-2018 IPR026022 PhoU domain STK_13770 9c6a84b89d3fe6494f58103ff84541fc 348 SUPERFAMILY SSF89447 8 55 8.72E-5 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily STK_13770 9c6a84b89d3fe6494f58103ff84541fc 348 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 15 53 3.2E-8 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_13770 9c6a84b89d3fe6494f58103ff84541fc 348 SMART SM00966 11 57 3.0E-7 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_17810 be0a8efb28874fbaa54c0f9c8e425f4c 744 SMART SM01008 18 135 2.3E-44 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead STK_17810 be0a8efb28874fbaa54c0f9c8e425f4c 744 Gene3D G3DSA:3.90.1170.50 32 135 8.4E-107 T 23-10-2018 STK_17810 be0a8efb28874fbaa54c0f9c8e425f4c 744 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 18 135 5.2E-26 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead STK_17810 be0a8efb28874fbaa54c0f9c8e425f4c 744 Gene3D G3DSA:3.30.365.10 455 604 2.1E-109 T 23-10-2018 STK_17810 be0a8efb28874fbaa54c0f9c8e425f4c 744 Gene3D G3DSA:3.30.365.10 136 360 8.4E-107 T 23-10-2018 STK_17810 be0a8efb28874fbaa54c0f9c8e425f4c 744 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 150 687 2.8E-157 T 23-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 STK_17810 be0a8efb28874fbaa54c0f9c8e425f4c 744 Gene3D G3DSA:3.30.365.10 368 728 2.1E-109 T 23-10-2018 STK_17810 be0a8efb28874fbaa54c0f9c8e425f4c 744 SUPERFAMILY SSF56003 127 744 9.68E-181 T 23-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 STK_17810 be0a8efb28874fbaa54c0f9c8e425f4c 744 SUPERFAMILY SSF54665 2 155 6.41E-41 T 23-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily STK_17810 be0a8efb28874fbaa54c0f9c8e425f4c 744 Gene3D G3DSA:3.30.365.10 17 284 8.4E-107 T 23-10-2018 STK_04520 4e2842f8251e3a762bd2d36473268b14 401 SUPERFAMILY SSF51161 236 394 4.32E-27 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily STK_04520 4e2842f8251e3a762bd2d36473268b14 401 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 245 278 9.4E-6 T 23-10-2018 IPR001451 Hexapeptide repeat STK_04520 4e2842f8251e3a762bd2d36473268b14 401 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 356 391 3.9E-7 T 23-10-2018 IPR001451 Hexapeptide repeat STK_04520 4e2842f8251e3a762bd2d36473268b14 401 Gene3D G3DSA:3.90.550.10 1 210 4.6E-72 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_04520 4e2842f8251e3a762bd2d36473268b14 401 Gene3D G3DSA:2.160.10.10 211 401 2.0E-58 T 23-10-2018 STK_04520 4e2842f8251e3a762bd2d36473268b14 401 TIGRFAM TIGR03992 Arch_glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 1 389 1.8E-163 T 23-10-2018 IPR023915 UDP-GlcNAc diphosphorylase/GlcNAc-1-P N-acetyltransferase, GlmU, archaeal-type GO:0003977|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 STK_04520 4e2842f8251e3a762bd2d36473268b14 401 Pfam PF00483 Nucleotidyl transferase 2 220 1.0E-35 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 STK_04520 4e2842f8251e3a762bd2d36473268b14 401 SUPERFAMILY SSF53448 1 303 6.44E-61 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_09430 21eda1ab0cd74873bdf3b6eb9957a313 318 SUPERFAMILY SSF56747 3 313 4.8E-86 T 23-10-2018 STK_09430 21eda1ab0cd74873bdf3b6eb9957a313 318 Hamap MF_00700 DNA primase small subunit PriS [priS]. 7 309 28.325 T 23-10-2018 IPR023639 DNA primase small subunit PriS GO:0003896 STK_09430 21eda1ab0cd74873bdf3b6eb9957a313 318 Gene3D G3DSA:3.90.920.30 1 318 4.1E-106 T 23-10-2018 STK_12280 dad33796db4677e41c19dfdcd170b1d2 193 Pfam PF00117 Glutamine amidotransferase class-I 6 192 1.1E-47 T 23-10-2018 IPR017926 Glutamine amidotransferase STK_12280 dad33796db4677e41c19dfdcd170b1d2 193 SUPERFAMILY SSF52317 2 191 3.63E-53 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_12280 dad33796db4677e41c19dfdcd170b1d2 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 79 90 1.1E-14 T 23-10-2018 STK_12280 dad33796db4677e41c19dfdcd170b1d2 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 1.1E-14 T 23-10-2018 STK_12280 dad33796db4677e41c19dfdcd170b1d2 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 49 58 1.1E-14 T 23-10-2018 STK_12280 dad33796db4677e41c19dfdcd170b1d2 193 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 5 191 1.2E-57 T 23-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 STK_12280 dad33796db4677e41c19dfdcd170b1d2 193 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 46 60 5.2E-9 T 23-10-2018 STK_12280 dad33796db4677e41c19dfdcd170b1d2 193 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 79 95 5.2E-9 T 23-10-2018 STK_12280 dad33796db4677e41c19dfdcd170b1d2 193 Gene3D G3DSA:3.40.50.880 1 193 1.5E-66 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_12280 dad33796db4677e41c19dfdcd170b1d2 193 PRINTS PR00097 Anthranilate synthase component II signature 79 90 3.7E-33 T 23-10-2018 STK_12280 dad33796db4677e41c19dfdcd170b1d2 193 PRINTS PR00097 Anthranilate synthase component II signature 125 137 3.7E-33 T 23-10-2018 STK_12280 dad33796db4677e41c19dfdcd170b1d2 193 PRINTS PR00097 Anthranilate synthase component II signature 4 18 3.7E-33 T 23-10-2018 STK_12280 dad33796db4677e41c19dfdcd170b1d2 193 PRINTS PR00097 Anthranilate synthase component II signature 104 112 3.7E-33 T 23-10-2018 STK_12280 dad33796db4677e41c19dfdcd170b1d2 193 PRINTS PR00097 Anthranilate synthase component II signature 169 182 3.7E-33 T 23-10-2018 STK_12280 dad33796db4677e41c19dfdcd170b1d2 193 PRINTS PR00097 Anthranilate synthase component II signature 49 58 3.7E-33 T 23-10-2018 STK_24950 dd61a260e835d26ddb954affbb30c141 202 SUPERFAMILY SSF46955 3 50 2.93E-8 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily STK_24950 dd61a260e835d26ddb954affbb30c141 202 ProSitePatterns PS00397 Site-specific recombinases active site. 62 70 - T 23-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 STK_24950 dd61a260e835d26ddb954affbb30c141 202 SMART SM00857 59 192 5.7E-23 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 STK_24950 dd61a260e835d26ddb954affbb30c141 202 Pfam PF12728 Helix-turn-helix domain 4 51 1.0E-14 T 23-10-2018 STK_24950 dd61a260e835d26ddb954affbb30c141 202 Pfam PF00239 Resolvase, N terminal domain 59 186 1.1E-25 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 STK_24950 dd61a260e835d26ddb954affbb30c141 202 Gene3D G3DSA:1.10.1660.10 2 55 4.0E-6 T 23-10-2018 STK_24950 dd61a260e835d26ddb954affbb30c141 202 Gene3D G3DSA:3.40.50.1390 56 156 1.1E-25 T 23-10-2018 STK_24950 dd61a260e835d26ddb954affbb30c141 202 SUPERFAMILY SSF53041 58 187 8.24E-23 T 23-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 STK_24950 dd61a260e835d26ddb954affbb30c141 202 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 50 8.4E-10 T 23-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 STK_13000 2d0ca111efcb4a93a967e827c5ef3d32 226 TIGRFAM TIGR02076 pyrH_arch: putative uridylate kinase 4 224 2.5E-81 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 STK_13000 2d0ca111efcb4a93a967e827c5ef3d32 226 Pfam PF00696 Amino acid kinase family 1 203 2.5E-32 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 STK_13000 2d0ca111efcb4a93a967e827c5ef3d32 226 Gene3D G3DSA:3.40.1160.10 1 226 5.2E-64 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily STK_13000 2d0ca111efcb4a93a967e827c5ef3d32 226 SUPERFAMILY SSF53633 2 224 1.57E-43 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily STK_13000 2d0ca111efcb4a93a967e827c5ef3d32 226 Hamap MF_01220_A Uridylate kinase [pyrH]. 1 225 36.74 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 STK_13000 2d0ca111efcb4a93a967e827c5ef3d32 226 PIRSF PIRSF005650 1 226 6.8E-56 T 23-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 STK_13020 27bc743a89c9099f5a78184d9a8f59b0 219 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 47 214 8.2E-41 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 STK_13020 27bc743a89c9099f5a78184d9a8f59b0 219 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 4 215 5.8E-41 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 STK_13020 27bc743a89c9099f5a78184d9a8f59b0 219 Gene3D G3DSA:3.40.50.1360 4 214 3.4E-48 T 23-10-2018 STK_13020 27bc743a89c9099f5a78184d9a8f59b0 219 SUPERFAMILY SSF75445 123 201 1.44E-16 T 23-10-2018 STK_13020 27bc743a89c9099f5a78184d9a8f59b0 219 Gene3D G3DSA:3.30.70.260 123 198 3.4E-48 T 23-10-2018 STK_13020 27bc743a89c9099f5a78184d9a8f59b0 219 SUPERFAMILY SSF100950 2 141 3.29E-26 T 23-10-2018 IPR037171 NagB/RpiA transferase-like STK_06250 f50a89ff200b2ddc6765a876938c3c6b 945 Pfam PF09334 tRNA synthetases class I (M) 584 676 4.4E-9 T 23-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_06250 f50a89ff200b2ddc6765a876938c3c6b 945 Pfam PF08264 Anticodon-binding domain of tRNA 699 824 2.4E-21 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 STK_06250 f50a89ff200b2ddc6765a876938c3c6b 945 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 13 505 1.2E-47 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_06250 f50a89ff200b2ddc6765a876938c3c6b 945 SUPERFAMILY SSF50677 207 426 2.83E-28 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 STK_06250 f50a89ff200b2ddc6765a876938c3c6b 945 Gene3D G3DSA:3.90.740.10 202 436 7.6E-236 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 STK_06250 f50a89ff200b2ddc6765a876938c3c6b 945 Gene3D G3DSA:3.30.2320.20 806 944 1.3E-8 T 23-10-2018 STK_06250 f50a89ff200b2ddc6765a876938c3c6b 945 Gene3D G3DSA:1.10.10.720 834 890 1.3E-8 T 23-10-2018 STK_06250 f50a89ff200b2ddc6765a876938c3c6b 945 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 9 943 5.4E-241 T 23-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 STK_06250 f50a89ff200b2ddc6765a876938c3c6b 945 Gene3D G3DSA:1.10.730.10 666 779 4.1E-16 T 23-10-2018 STK_06250 f50a89ff200b2ddc6765a876938c3c6b 945 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 7 945 16.9 T 23-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 STK_06250 f50a89ff200b2ddc6765a876938c3c6b 945 SUPERFAMILY SSF47323 692 869 7.1E-27 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_06250 f50a89ff200b2ddc6765a876938c3c6b 945 Gene3D G3DSA:3.40.50.620 11 662 7.6E-236 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_06250 f50a89ff200b2ddc6765a876938c3c6b 945 SUPERFAMILY SSF52374 8 671 1.58E-93 T 23-10-2018 STK_10510 01183ce9940686c05d458bdc59c974e2 375 Gene3D G3DSA:1.20.1250.20 191 373 1.2E-12 T 23-10-2018 STK_10510 01183ce9940686c05d458bdc59c974e2 375 SUPERFAMILY SSF103473 3 371 2.09E-41 T 23-10-2018 IPR036259 MFS transporter superfamily STK_10510 01183ce9940686c05d458bdc59c974e2 375 Gene3D G3DSA:1.20.1250.20 2 182 2.2E-21 T 23-10-2018 STK_10510 01183ce9940686c05d458bdc59c974e2 375 Pfam PF07690 Major Facilitator Superfamily 14 337 2.9E-27 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_22390 c5847be80760b0eed2f0f4950631a487 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 257 1.4E-49 T 23-10-2018 STK_22390 c5847be80760b0eed2f0f4950631a487 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.8E-27 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_22390 c5847be80760b0eed2f0f4950631a487 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.8E-27 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_22390 c5847be80760b0eed2f0f4950631a487 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.8E-27 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_22390 c5847be80760b0eed2f0f4950631a487 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.8E-27 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_22390 c5847be80760b0eed2f0f4950631a487 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.8E-27 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_22390 c5847be80760b0eed2f0f4950631a487 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.8E-27 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_22390 c5847be80760b0eed2f0f4950631a487 262 Gene3D G3DSA:3.40.50.720 2 261 4.6E-59 T 23-10-2018 STK_22390 c5847be80760b0eed2f0f4950631a487 262 SUPERFAMILY SSF51735 9 257 7.82E-67 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_21830 24eef94c94c51407903425fb0c227866 279 SUPERFAMILY SSF103481 174 270 1.44E-11 T 23-10-2018 STK_21830 24eef94c94c51407903425fb0c227866 279 SUPERFAMILY SSF103481 39 129 1.96E-9 T 23-10-2018 STK_21830 24eef94c94c51407903425fb0c227866 279 Pfam PF00892 EamA-like transporter family 7 129 4.0E-14 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 STK_21830 24eef94c94c51407903425fb0c227866 279 Pfam PF00892 EamA-like transporter family 137 269 2.3E-17 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 STK_15440 cb7ec205a0e9692cfadb39e7236e992b 417 Pfam PF02541 Ppx/GppA phosphatase family 24 285 4.4E-43 T 23-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 STK_15440 cb7ec205a0e9692cfadb39e7236e992b 417 Gene3D G3DSA:3.30.420.150 108 286 1.8E-42 T 23-10-2018 STK_15440 cb7ec205a0e9692cfadb39e7236e992b 417 SUPERFAMILY SSF53067 3 124 1.08E-28 T 23-10-2018 STK_15440 cb7ec205a0e9692cfadb39e7236e992b 417 SUPERFAMILY SSF53067 126 286 9.06E-33 T 23-10-2018 STK_15440 cb7ec205a0e9692cfadb39e7236e992b 417 Gene3D G3DSA:3.30.420.40 1 107 1.1E-21 T 23-10-2018 STK_10640 712e02e477710f40386f0347c4cdaea3 107 Gene3D G3DSA:1.10.10.10 8 105 2.7E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_10640 712e02e477710f40386f0347c4cdaea3 107 SUPERFAMILY SSF46785 16 101 1.24E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_10640 712e02e477710f40386f0347c4cdaea3 107 Pfam PF13601 Winged helix DNA-binding domain 25 102 6.8E-12 T 23-10-2018 IPR027395 Winged helix DNA-binding domain STK_10640 712e02e477710f40386f0347c4cdaea3 107 SMART SM00418 13 97 2.6E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 STK_03240 a485f00f7cb687d956c031e83b9d1bab 197 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 9 55 - T 23-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 STK_03240 a485f00f7cb687d956c031e83b9d1bab 197 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 6 187 5.7E-77 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 STK_03240 a485f00f7cb687d956c031e83b9d1bab 197 Pfam PF00227 Proteasome subunit 6 183 1.0E-49 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 STK_03240 a485f00f7cb687d956c031e83b9d1bab 197 Hamap MF_02113_A Proteasome subunit beta [prcB]. 1 196 36.161 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 STK_03240 a485f00f7cb687d956c031e83b9d1bab 197 SUPERFAMILY SSF56235 7 187 6.31E-55 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_03240 a485f00f7cb687d956c031e83b9d1bab 197 PRINTS PR00141 Proteasome component signature 133 144 3.1E-7 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 STK_03240 a485f00f7cb687d956c031e83b9d1bab 197 PRINTS PR00141 Proteasome component signature 144 155 3.1E-7 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 STK_03240 a485f00f7cb687d956c031e83b9d1bab 197 PRINTS PR00141 Proteasome component signature 13 28 3.1E-7 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 STK_03240 a485f00f7cb687d956c031e83b9d1bab 197 PRINTS PR00141 Proteasome component signature 169 180 3.1E-7 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 STK_03240 a485f00f7cb687d956c031e83b9d1bab 197 Gene3D G3DSA:3.60.20.10 6 196 5.5E-58 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_04240 1ec98ade91fdada70c17fa68bc3e20e8 225 Gene3D G3DSA:3.30.1140.32 88 225 1.1E-33 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04240 1ec98ade91fdada70c17fa68bc3e20e8 225 Hamap MF_01309_A 30S ribosomal protein S3 [rpsC]. 3 197 40.258 T 23-10-2018 IPR027488 Ribosomal protein S3, archaeal GO:0003735|GO:0006412|GO:0015935 STK_04240 1ec98ade91fdada70c17fa68bc3e20e8 225 SMART SM00322 39 105 1.2E-6 T 23-10-2018 IPR004087 K Homology domain GO:0003676 STK_04240 1ec98ade91fdada70c17fa68bc3e20e8 225 SUPERFAMILY SSF54814 8 96 3.66E-24 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 STK_04240 1ec98ade91fdada70c17fa68bc3e20e8 225 Pfam PF07650 KH domain 18 88 4.4E-15 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04240 1ec98ade91fdada70c17fa68bc3e20e8 225 SUPERFAMILY SSF54821 87 186 4.84E-25 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04240 1ec98ade91fdada70c17fa68bc3e20e8 225 ProSitePatterns PS00548 Ribosomal protein S3 signature. 142 178 - T 23-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04240 1ec98ade91fdada70c17fa68bc3e20e8 225 Gene3D G3DSA:3.30.300.20 2 87 5.8E-23 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta STK_04240 1ec98ade91fdada70c17fa68bc3e20e8 225 Pfam PF00189 Ribosomal protein S3, C-terminal domain 101 183 4.5E-22 T 23-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04240 1ec98ade91fdada70c17fa68bc3e20e8 225 TIGRFAM TIGR01008 uS3_euk_arch: ribosomal protein uS3 4 196 3.6E-71 T 23-10-2018 IPR005703 Ribosomal protein S3, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_09880 553190bdcf77de4e99fec0d8fc151941 400 Pfam PF04895 Archaeal Nre, C-terminal 294 393 1.1E-34 T 23-10-2018 IPR006979 Archaeal Nre, C-terminal STK_09880 553190bdcf77de4e99fec0d8fc151941 400 Pfam PF04894 Archaeal Nre, N-terminal 16 281 7.5E-97 T 23-10-2018 IPR006978 Archaeal Nre, N-terminal STK_09880 553190bdcf77de4e99fec0d8fc151941 400 Hamap MF_02096 DNA repair protein. 2 398 34.24 T 23-10-2018 IPR033167 Archaeal Nre GO:0006281 STK_25120 1af066fb6d5af96201d8088ba10c2d41 268 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 29 238 9.2E-8 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain STK_25120 1af066fb6d5af96201d8088ba10c2d41 268 SUPERFAMILY SSF52540 25 237 1.66E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_25120 1af066fb6d5af96201d8088ba10c2d41 268 Gene3D G3DSA:3.40.50.300 26 243 2.4E-12 T 23-10-2018 STK_02420 5b4c28a57a528146e0b972274b545995 455 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 452 3.6E-167 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 STK_02420 5b4c28a57a528146e0b972274b545995 455 Gene3D G3DSA:3.40.120.10 162 358 1.3E-72 T 23-10-2018 STK_02420 5b4c28a57a528146e0b972274b545995 455 SUPERFAMILY SSF55957 361 454 8.5E-22 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 STK_02420 5b4c28a57a528146e0b972274b545995 455 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 154 254 2.7E-22 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 STK_02420 5b4c28a57a528146e0b972274b545995 455 Gene3D G3DSA:3.40.120.10 1 150 1.8E-59 T 23-10-2018 STK_02420 5b4c28a57a528146e0b972274b545995 455 SUPERFAMILY SSF53738 153 256 8.24E-24 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 STK_02420 5b4c28a57a528146e0b972274b545995 455 SUPERFAMILY SSF53738 3 179 2.08E-44 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 STK_02420 5b4c28a57a528146e0b972274b545995 455 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 133 4.0E-45 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 STK_02420 5b4c28a57a528146e0b972274b545995 455 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 259 370 5.7E-19 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 STK_02420 5b4c28a57a528146e0b972274b545995 455 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 382 451 1.1E-10 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 STK_02420 5b4c28a57a528146e0b972274b545995 455 SUPERFAMILY SSF53738 258 366 1.88E-18 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 STK_02420 5b4c28a57a528146e0b972274b545995 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 5.1E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 STK_02420 5b4c28a57a528146e0b972274b545995 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 90 104 5.1E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 STK_02420 5b4c28a57a528146e0b972274b545995 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 234 249 5.1E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 STK_02420 5b4c28a57a528146e0b972274b545995 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 206 219 5.1E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 STK_02420 5b4c28a57a528146e0b972274b545995 455 Gene3D G3DSA:3.40.120.10 255 363 1.3E-72 T 23-10-2018 STK_02420 5b4c28a57a528146e0b972274b545995 455 Gene3D G3DSA:3.30.310.50 371 455 4.0E-32 T 23-10-2018 STK_02420 5b4c28a57a528146e0b972274b545995 455 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 91 100 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 STK_04380 a8c98eedccc68a0ea57d535f2d034775 335 Gene3D G3DSA:3.50.50.60 126 249 4.0E-94 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_04380 a8c98eedccc68a0ea57d535f2d034775 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 7.8E-29 T 23-10-2018 STK_04380 a8c98eedccc68a0ea57d535f2d034775 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 7.8E-29 T 23-10-2018 STK_04380 a8c98eedccc68a0ea57d535f2d034775 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 7.8E-29 T 23-10-2018 STK_04380 a8c98eedccc68a0ea57d535f2d034775 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 7.8E-29 T 23-10-2018 STK_04380 a8c98eedccc68a0ea57d535f2d034775 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 7.8E-29 T 23-10-2018 STK_04380 a8c98eedccc68a0ea57d535f2d034775 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 200 216 8.7E-49 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_04380 a8c98eedccc68a0ea57d535f2d034775 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 64 74 8.7E-49 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_04380 a8c98eedccc68a0ea57d535f2d034775 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 110 118 8.7E-49 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_04380 a8c98eedccc68a0ea57d535f2d034775 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 147 171 8.7E-49 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_04380 a8c98eedccc68a0ea57d535f2d034775 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 238 259 8.7E-49 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_04380 a8c98eedccc68a0ea57d535f2d034775 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 44 59 8.7E-49 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_04380 a8c98eedccc68a0ea57d535f2d034775 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 12 34 8.7E-49 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_04380 a8c98eedccc68a0ea57d535f2d034775 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 272 290 8.7E-49 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_04380 a8c98eedccc68a0ea57d535f2d034775 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 132 144 8.7E-49 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_04380 a8c98eedccc68a0ea57d535f2d034775 335 SUPERFAMILY SSF51905 6 309 1.62E-46 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_04380 a8c98eedccc68a0ea57d535f2d034775 335 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 298 1.5E-41 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 STK_04380 a8c98eedccc68a0ea57d535f2d034775 335 Gene3D G3DSA:3.50.50.60 13 308 4.0E-94 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_04370 55711e88589bd7349e39b9387259214a 737 SMART SM00838 628 715 1.5E-43 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like STK_04370 55711e88589bd7349e39b9387259214a 737 SUPERFAMILY SSF52540 6 238 1.46E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_04370 55711e88589bd7349e39b9387259214a 737 SUPERFAMILY SSF54980 394 470 5.4E-22 T 23-10-2018 IPR035647 EF-G domain III/V-like STK_04370 55711e88589bd7349e39b9387259214a 737 SUPERFAMILY SSF54980 631 721 1.87E-22 T 23-10-2018 IPR035647 EF-G domain III/V-like STK_04370 55711e88589bd7349e39b9387259214a 737 Gene3D G3DSA:3.40.50.300 5 221 8.3E-71 T 23-10-2018 STK_04370 55711e88589bd7349e39b9387259214a 737 SUPERFAMILY SSF50447 261 378 1.37E-28 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily STK_04370 55711e88589bd7349e39b9387259214a 737 Pfam PF03764 Elongation factor G, domain IV 518 625 1.7E-29 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 STK_04370 55711e88589bd7349e39b9387259214a 737 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 59 74 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site STK_04370 55711e88589bd7349e39b9387259214a 737 Gene3D G3DSA:3.30.70.870 395 472 2.1E-24 T 23-10-2018 STK_04370 55711e88589bd7349e39b9387259214a 737 Pfam PF00009 Elongation factor Tu GTP binding domain 19 259 5.3E-62 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_04370 55711e88589bd7349e39b9387259214a 737 SUPERFAMILY SSF54211 470 630 1.62E-51 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold STK_04370 55711e88589bd7349e39b9387259214a 737 SMART SM00889 512 626 3.8E-21 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 STK_04370 55711e88589bd7349e39b9387259214a 737 Hamap MF_00054_A Elongation factor G [fusA]. 1 732 42.449 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 STK_04370 55711e88589bd7349e39b9387259214a 737 TIGRFAM TIGR00490 aEF-2: translation elongation factor aEF-2 3 727 1.7E-279 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 STK_04370 55711e88589bd7349e39b9387259214a 737 PRINTS PR00315 GTP-binding elongation factor signature 22 35 4.1E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_04370 55711e88589bd7349e39b9387259214a 737 PRINTS PR00315 GTP-binding elongation factor signature 90 100 4.1E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_04370 55711e88589bd7349e39b9387259214a 737 PRINTS PR00315 GTP-binding elongation factor signature 142 151 4.1E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_04370 55711e88589bd7349e39b9387259214a 737 PRINTS PR00315 GTP-binding elongation factor signature 106 117 4.1E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_04370 55711e88589bd7349e39b9387259214a 737 PRINTS PR00315 GTP-binding elongation factor signature 66 74 4.1E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_04370 55711e88589bd7349e39b9387259214a 737 Pfam PF00679 Elongation factor G C-terminus 629 711 4.0E-23 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like STK_04370 55711e88589bd7349e39b9387259214a 737 Pfam PF14492 Elongation Factor G, domain II 393 466 3.2E-23 T 23-10-2018 STK_04370 55711e88589bd7349e39b9387259214a 737 Gene3D G3DSA:2.40.30.10 261 377 7.0E-23 T 23-10-2018 STK_04370 55711e88589bd7349e39b9387259214a 737 Pfam PF03144 Elongation factor Tu domain 2 308 373 2.3E-13 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 STK_04370 55711e88589bd7349e39b9387259214a 737 Gene3D G3DSA:3.30.230.10 479 728 5.2E-84 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup STK_04370 55711e88589bd7349e39b9387259214a 737 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 157 1.4E-20 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 STK_04370 55711e88589bd7349e39b9387259214a 737 Gene3D G3DSA:3.30.70.240 473 725 5.2E-84 T 23-10-2018 STK_14710 45d3b3e0dab0f6f5bc058da42950bdf6 141 PRINTS PR00332 Histidine triad family signature 94 104 4.8E-18 T 23-10-2018 IPR001310 Histidine triad (HIT) protein STK_14710 45d3b3e0dab0f6f5bc058da42950bdf6 141 PRINTS PR00332 Histidine triad family signature 28 46 4.8E-18 T 23-10-2018 IPR001310 Histidine triad (HIT) protein STK_14710 45d3b3e0dab0f6f5bc058da42950bdf6 141 PRINTS PR00332 Histidine triad family signature 7 23 4.8E-18 T 23-10-2018 IPR001310 Histidine triad (HIT) protein STK_14710 45d3b3e0dab0f6f5bc058da42950bdf6 141 SUPERFAMILY SSF54197 4 137 4.49E-44 T 23-10-2018 IPR036265 HIT-like superfamily STK_14710 45d3b3e0dab0f6f5bc058da42950bdf6 141 Pfam PF01230 HIT domain 14 108 1.1E-30 T 23-10-2018 IPR001310 Histidine triad (HIT) protein STK_14710 45d3b3e0dab0f6f5bc058da42950bdf6 141 ProSitePatterns PS00892 HIT domain signature. 87 105 - T 23-10-2018 IPR019808 Histidine triad, conserved site STK_14710 45d3b3e0dab0f6f5bc058da42950bdf6 141 Gene3D G3DSA:3.30.428.10 1 139 1.0E-47 T 23-10-2018 IPR036265 HIT-like superfamily STK_17840 540e7e7bce26772bb2b89a4acf6534fc 267 Pfam PF00581 Rhodanese-like domain 4 111 1.5E-15 T 23-10-2018 IPR001763 Rhodanese-like domain STK_17840 540e7e7bce26772bb2b89a4acf6534fc 267 Pfam PF00581 Rhodanese-like domain 143 257 1.5E-18 T 23-10-2018 IPR001763 Rhodanese-like domain STK_17840 540e7e7bce26772bb2b89a4acf6534fc 267 ProSitePatterns PS00683 Rhodanese C-terminal signature. 247 257 - T 23-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 STK_17840 540e7e7bce26772bb2b89a4acf6534fc 267 Gene3D G3DSA:3.40.250.10 1 134 6.0E-34 T 23-10-2018 IPR036873 Rhodanese-like domain superfamily STK_17840 540e7e7bce26772bb2b89a4acf6534fc 267 Gene3D G3DSA:3.40.250.10 141 267 3.2E-38 T 23-10-2018 IPR036873 Rhodanese-like domain superfamily STK_17840 540e7e7bce26772bb2b89a4acf6534fc 267 SUPERFAMILY SSF52821 2 127 3.8E-33 T 23-10-2018 IPR036873 Rhodanese-like domain superfamily STK_17840 540e7e7bce26772bb2b89a4acf6534fc 267 SMART SM00450 3 115 1.9E-18 T 23-10-2018 IPR001763 Rhodanese-like domain STK_17840 540e7e7bce26772bb2b89a4acf6534fc 267 SMART SM00450 138 263 1.4E-24 T 23-10-2018 IPR001763 Rhodanese-like domain STK_17840 540e7e7bce26772bb2b89a4acf6534fc 267 SUPERFAMILY SSF52821 144 266 2.88E-34 T 23-10-2018 IPR036873 Rhodanese-like domain superfamily STK_02330 3006e236a3811fbdee71eb66def0bb41 288 Pfam PF01163 RIO1 family 109 274 3.2E-38 T 23-10-2018 STK_02330 3006e236a3811fbdee71eb66def0bb41 288 Gene3D G3DSA:1.10.510.10 192 287 4.6E-24 T 23-10-2018 STK_02330 3006e236a3811fbdee71eb66def0bb41 288 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 223 234 - T 23-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 STK_02330 3006e236a3811fbdee71eb66def0bb41 288 Pfam PF09202 Rio2, N-terminal 16 89 1.9E-13 T 23-10-2018 IPR015285 RIO2 kinase winged helix domain, N-terminal GO:0004674|GO:0005524|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 STK_02330 3006e236a3811fbdee71eb66def0bb41 288 SMART SM00090 67 287 6.8E-38 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 STK_02330 3006e236a3811fbdee71eb66def0bb41 288 Gene3D G3DSA:1.10.10.10 4 93 1.5E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_02330 3006e236a3811fbdee71eb66def0bb41 288 SUPERFAMILY SSF56112 101 269 3.64E-25 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily STK_02330 3006e236a3811fbdee71eb66def0bb41 288 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 223 235 - T 23-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 STK_02330 3006e236a3811fbdee71eb66def0bb41 288 Gene3D G3DSA:3.30.200.20 95 191 1.6E-25 T 23-10-2018 STK_02330 3006e236a3811fbdee71eb66def0bb41 288 SUPERFAMILY SSF46785 6 91 4.99E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_20370 5fc81915f9bbc1ece0d9c4c1101d68ee 399 SUPERFAMILY SSF82544 4 398 5.36E-90 T 23-10-2018 STK_20370 5fc81915f9bbc1ece0d9c4c1101d68ee 399 Gene3D G3DSA:3.40.50.10180 19 239 1.1E-90 T 23-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 STK_20370 5fc81915f9bbc1ece0d9c4c1101d68ee 399 Pfam PF05161 MOFRL family 291 392 1.0E-24 T 23-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 STK_20370 5fc81915f9bbc1ece0d9c4c1101d68ee 399 Gene3D G3DSA:3.40.1480.10 240 395 1.1E-90 T 23-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily STK_20370 5fc81915f9bbc1ece0d9c4c1101d68ee 399 Pfam PF13660 Domain of unknown function (DUF4147) 2 217 5.5E-48 T 23-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 STK_07260 4235b34193a7f5426f3e74083a9b0348 494 SUPERFAMILY SSF56645 5 276 3.66E-77 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 STK_07260 4235b34193a7f5426f3e74083a9b0348 494 Gene3D G3DSA:1.10.3140.10 4 149 4.4E-36 T 23-10-2018 STK_07260 4235b34193a7f5426f3e74083a9b0348 494 Gene3D G3DSA:2.40.110.10 150 277 1.6E-36 T 23-10-2018 STK_07260 4235b34193a7f5426f3e74083a9b0348 494 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 8 275 1.7E-87 T 23-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal STK_07260 4235b34193a7f5426f3e74083a9b0348 494 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 287 480 2.1E-49 T 23-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal STK_07260 4235b34193a7f5426f3e74083a9b0348 494 PIRSF PIRSF000331 3 494 4.4E-171 T 23-10-2018 IPR004925 HpaB/PvcC/4-BUDH STK_07260 4235b34193a7f5426f3e74083a9b0348 494 SUPERFAMILY SSF47203 267 480 2.03E-37 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 STK_07260 4235b34193a7f5426f3e74083a9b0348 494 Gene3D G3DSA:1.20.140.10 281 490 1.5E-49 T 23-10-2018 STK_07080 96e15e1331414d6c81643ec439879b37 170 Gene3D G3DSA:2.20.28.70 133 169 6.0E-6 T 23-10-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 STK_07080 96e15e1331414d6c81643ec439879b37 170 Pfam PF13240 zinc-ribbon domain 149 170 3.0E-6 T 23-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 STK_07080 96e15e1331414d6c81643ec439879b37 170 SUPERFAMILY SSF57829 140 168 9.34E-5 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 STK_20750 84e57b66cff9887ce695d6686faf4974 408 SMART SM00493 165 237 2.2E-7 T 23-10-2018 IPR006171 TOPRIM domain STK_20750 84e57b66cff9887ce695d6686faf4974 408 Pfam PF13662 Toprim domain 166 230 3.9E-9 T 23-10-2018 IPR006171 TOPRIM domain STK_20750 84e57b66cff9887ce695d6686faf4974 408 Hamap MF_00007 DNA primase DnaG [dnaG]. 1 403 32.619 T 23-10-2018 IPR020607 DNA primase DnaG, archaea GO:0000178|GO:0003896|GO:0008143 STK_20750 84e57b66cff9887ce695d6686faf4974 408 SUPERFAMILY SSF110455 165 265 1.2E-10 T 23-10-2018 STK_20750 84e57b66cff9887ce695d6686faf4974 408 Gene3D G3DSA:3.40.1360.10 160 257 1.2E-13 T 23-10-2018 STK_13067 bef9ced1786bdf22160bf47fed69a1f1 54 Gene3D G3DSA:3.30.2310.20 1 53 9.3E-6 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily STK_13067 bef9ced1786bdf22160bf47fed69a1f1 54 SUPERFAMILY SSF143011 9 50 1.44E-6 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily STK_09290 99506dae1d94aa1e44d6d235da4cbd5a 704 Gene3D G3DSA:3.30.1590.10 88 200 7.8E-43 T 23-10-2018 STK_09290 99506dae1d94aa1e44d6d235da4cbd5a 704 SUPERFAMILY SSF51445 13 638 5.87E-128 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily STK_09290 99506dae1d94aa1e44d6d235da4cbd5a 704 SMART SM00642 14 388 9.4E-8 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 STK_09290 99506dae1d94aa1e44d6d235da4cbd5a 704 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 4 667 3.4E-199 T 23-10-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 STK_09290 99506dae1d94aa1e44d6d235da4cbd5a 704 Gene3D G3DSA:3.30.750.90 4 87 3.1E-9 T 23-10-2018 STK_09290 99506dae1d94aa1e44d6d235da4cbd5a 704 Pfam PF00128 Alpha amylase, catalytic domain 17 332 4.3E-23 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 STK_09290 99506dae1d94aa1e44d6d235da4cbd5a 704 Gene3D G3DSA:2.60.40.1180 643 704 9.8E-37 T 23-10-2018 IPR013780 Glycosyl hydrolase, all-beta STK_09290 99506dae1d94aa1e44d6d235da4cbd5a 704 Pfam PF09196 Domain of unknown function (DUF1953) 642 704 2.5E-44 T 23-10-2018 IPR015279 Malto-oligosyltrehalose synthase, C-terminal STK_09290 99506dae1d94aa1e44d6d235da4cbd5a 704 Gene3D G3DSA:3.20.20.80 498 642 5.2E-33 T 23-10-2018 STK_09290 99506dae1d94aa1e44d6d235da4cbd5a 704 Gene3D G3DSA:3.20.20.80 405 487 1.2E-11 T 23-10-2018 STK_09290 99506dae1d94aa1e44d6d235da4cbd5a 704 SUPERFAMILY SSF51011 642 704 3.52E-27 T 23-10-2018 STK_09290 99506dae1d94aa1e44d6d235da4cbd5a 704 Gene3D G3DSA:1.10.150.200 298 388 1.1E-52 T 23-10-2018 STK_22200 30af5c6cb040d7a4eb970f8a45d7dbca 167 Gene3D G3DSA:3.30.70.3270 41 166 1.5E-25 T 23-10-2018 STK_22200 30af5c6cb040d7a4eb970f8a45d7dbca 167 SUPERFAMILY SSF54862 41 133 4.81E-24 T 23-10-2018 STK_22200 30af5c6cb040d7a4eb970f8a45d7dbca 167 Pfam PF12838 4Fe-4S dicluster domain 63 110 5.1E-10 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_22200 30af5c6cb040d7a4eb970f8a45d7dbca 167 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 96 107 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_22200 30af5c6cb040d7a4eb970f8a45d7dbca 167 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 25 133 1.0E-36 T 23-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_18000 efcef04ec22b1ebb398fcca0c71e4520 369 SUPERFAMILY SSF53901 242 363 1.58E-13 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_18000 efcef04ec22b1ebb398fcca0c71e4520 369 Gene3D G3DSA:3.40.47.10 1 367 1.3E-54 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_18000 efcef04ec22b1ebb398fcca0c71e4520 369 SUPERFAMILY SSF53901 3 223 1.15E-12 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_20635 4504e134859d171ec4dd6b0bab12d9e9 66 PIRSF PIRSF005653 1 66 6.0E-33 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 STK_20635 4504e134859d171ec4dd6b0bab12d9e9 66 SUPERFAMILY SSF46924 1 63 4.97E-29 T 23-10-2018 IPR023580 RNA polymerase subunit RPB10 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 STK_20635 4504e134859d171ec4dd6b0bab12d9e9 66 Gene3D G3DSA:1.10.10.60 1 66 8.6E-35 T 23-10-2018 STK_20635 4504e134859d171ec4dd6b0bab12d9e9 66 Hamap MF_00250 DNA-directed RNA polymerase subunit N [rpoN]. 1 63 23.228 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 STK_20635 4504e134859d171ec4dd6b0bab12d9e9 66 Pfam PF01194 RNA polymerases N / 8 kDa subunit 1 58 5.4E-32 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 STK_20635 4504e134859d171ec4dd6b0bab12d9e9 66 ProSitePatterns PS01112 RNA polymerases N / 8 Kd subunits signature. 2 11 - T 23-10-2018 IPR020789 RNA polymerases, subunit N, zinc binding site GO:0003677|GO:0003899|GO:0006351|GO:0008270 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 STK_20635 4504e134859d171ec4dd6b0bab12d9e9 66 ProDom PD006539 RNA POLYMERASE DNA-DIRECTED SUBUNIT TRANSFERASE NUCLEOTIDYLTRANSFERASE METAL-BINDING ZINC TRANSCRIPTION N 10 49 2.0E-17 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 STK_10220 250d8b044d05bd93b6fcd50d30ca129a 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 1.5E-15 T 23-10-2018 STK_10220 250d8b044d05bd93b6fcd50d30ca129a 150 Gene3D G3DSA:3.30.70.920 53 150 4.2E-25 T 23-10-2018 STK_10220 250d8b044d05bd93b6fcd50d30ca129a 150 Pfam PF01037 Lrp/AsnC ligand binding domain 73 139 3.8E-10 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain STK_10220 250d8b044d05bd93b6fcd50d30ca129a 150 SUPERFAMILY SSF46785 1 59 2.89E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_10220 250d8b044d05bd93b6fcd50d30ca129a 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 5.1E-10 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_10220 250d8b044d05bd93b6fcd50d30ca129a 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 5.1E-10 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_10220 250d8b044d05bd93b6fcd50d30ca129a 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 5.1E-10 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_10220 250d8b044d05bd93b6fcd50d30ca129a 150 SUPERFAMILY SSF54909 62 142 9.79E-13 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel STK_10220 250d8b044d05bd93b6fcd50d30ca129a 150 SMART SM00344 1 109 6.7E-28 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 STK_10220 250d8b044d05bd93b6fcd50d30ca129a 150 Gene3D G3DSA:1.10.10.10 1 52 6.4E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_24220 64cd7c45803d1b22fd46b7e46b9b4fe9 388 Gene3D G3DSA:1.20.1250.20 4 383 2.6E-50 T 23-10-2018 STK_24220 64cd7c45803d1b22fd46b7e46b9b4fe9 388 ProSitePatterns PS00217 Sugar transport proteins signature 2. 103 128 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 STK_24220 64cd7c45803d1b22fd46b7e46b9b4fe9 388 Pfam PF07690 Major Facilitator Superfamily 17 338 3.3E-31 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_24220 64cd7c45803d1b22fd46b7e46b9b4fe9 388 SUPERFAMILY SSF103473 8 377 2.49E-52 T 23-10-2018 IPR036259 MFS transporter superfamily STK_14230 1ceb50b2a00af370fd4041a1b960083f 566 Gene3D G3DSA:3.40.50.620 54 409 1.6E-108 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_14230 1ceb50b2a00af370fd4041a1b960083f 566 Gene3D G3DSA:2.40.240.100 410 565 1.1E-40 T 23-10-2018 STK_14230 1ceb50b2a00af370fd4041a1b960083f 566 Hamap MF_02076 Glutamate--tRNA ligase [gltX]. 8 564 34.869 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 STK_14230 1ceb50b2a00af370fd4041a1b960083f 566 TIGRFAM TIGR00463 gltX_arch: glutamate--tRNA ligase 5 565 1.3E-165 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 STK_14230 1ceb50b2a00af370fd4041a1b960083f 566 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 99 405 6.1E-82 T 23-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 STK_14230 1ceb50b2a00af370fd4041a1b960083f 566 SUPERFAMILY SSF52374 99 414 4.56E-86 T 23-10-2018 STK_14230 1ceb50b2a00af370fd4041a1b960083f 566 Gene3D G3DSA:2.40.240.10 417 506 1.1E-40 T 23-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 STK_14230 1ceb50b2a00af370fd4041a1b960083f 566 PRINTS PR00987 Glutamyl-tRNA synthetase signature 102 114 2.3E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 STK_14230 1ceb50b2a00af370fd4041a1b960083f 566 PRINTS PR00987 Glutamyl-tRNA synthetase signature 131 144 2.3E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 STK_14230 1ceb50b2a00af370fd4041a1b960083f 566 PRINTS PR00987 Glutamyl-tRNA synthetase signature 116 127 2.3E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 STK_14230 1ceb50b2a00af370fd4041a1b960083f 566 PRINTS PR00987 Glutamyl-tRNA synthetase signature 281 291 2.3E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 STK_14230 1ceb50b2a00af370fd4041a1b960083f 566 PRINTS PR00987 Glutamyl-tRNA synthetase signature 297 305 2.3E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 STK_14230 1ceb50b2a00af370fd4041a1b960083f 566 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 408 552 6.1E-23 T 23-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 STK_14230 1ceb50b2a00af370fd4041a1b960083f 566 SUPERFAMILY SSF50715 408 563 1.26E-22 T 23-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 STK_13510 828c8c668ccda2ea593e9d996170b010 135 SUPERFAMILY SSF50249 16 113 2.06E-24 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_13510 828c8c668ccda2ea593e9d996170b010 135 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 52 109 4.4E-13 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal STK_11420 822cc74c009a5f8a9dc17931fbb28730 128 Pfam PF01909 Nucleotidyltransferase domain 31 84 1.6E-7 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_11420 822cc74c009a5f8a9dc17931fbb28730 128 SUPERFAMILY SSF81301 29 111 3.0E-15 T 23-10-2018 STK_11420 822cc74c009a5f8a9dc17931fbb28730 128 Gene3D G3DSA:3.30.460.10 26 123 6.3E-13 T 23-10-2018 STK_07300 615860f6fd5180f972d52f882efd97c6 662 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 22 650 4.5E-285 T 23-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 STK_07300 615860f6fd5180f972d52f882efd97c6 662 ProSitePatterns PS00455 Putative AMP-binding domain signature. 268 279 - T 23-10-2018 IPR020845 AMP-binding, conserved site STK_07300 615860f6fd5180f972d52f882efd97c6 662 Pfam PF00501 AMP-binding enzyme 83 531 9.1E-90 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 STK_07300 615860f6fd5180f972d52f882efd97c6 662 Gene3D G3DSA:3.40.50.12780 55 525 4.9E-100 T 23-10-2018 STK_07300 615860f6fd5180f972d52f882efd97c6 662 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 26 79 1.3E-21 T 23-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 STK_07300 615860f6fd5180f972d52f882efd97c6 662 Pfam PF13193 AMP-binding enzyme C-terminal domain 540 618 4.7E-27 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain STK_07300 615860f6fd5180f972d52f882efd97c6 662 SUPERFAMILY SSF56801 11 648 3.79E-172 T 23-10-2018 STK_07300 615860f6fd5180f972d52f882efd97c6 662 Gene3D G3DSA:3.30.300.30 527 658 3.0E-28 T 23-10-2018 STK_04030 0167ad774e5884ceb7fd953dcec0e240 184 SUPERFAMILY SSF53335 15 183 3.92E-30 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_04030 0167ad774e5884ceb7fd953dcec0e240 184 Pfam PF05175 Methyltransferase small domain 16 179 2.1E-34 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 STK_04030 0167ad774e5884ceb7fd953dcec0e240 184 Gene3D G3DSA:3.40.50.150 2 183 1.1E-35 T 23-10-2018 STK_05870 922befacb87de628cef9d86b499c1386 373 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 5 373 1.5E-146 T 23-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 STK_05870 922befacb87de628cef9d86b499c1386 373 Pfam PF00285 Citrate synthase, C-terminal domain 6 356 3.1E-127 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 STK_05870 922befacb87de628cef9d86b499c1386 373 ProSitePatterns PS00480 Citrate synthase signature. 251 263 - T 23-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 STK_05870 922befacb87de628cef9d86b499c1386 373 Gene3D G3DSA:1.10.230.10 217 320 3.0E-147 T 23-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain STK_05870 922befacb87de628cef9d86b499c1386 373 Gene3D G3DSA:1.10.580.10 18 345 3.0E-147 T 23-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 STK_05870 922befacb87de628cef9d86b499c1386 373 SUPERFAMILY SSF48256 4 373 2.88E-134 T 23-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 STK_05870 922befacb87de628cef9d86b499c1386 373 PIRSF PIRSF001369 1 373 2.3E-144 T 23-10-2018 IPR024176 Citrate synthase, bacterial-type STK_05870 922befacb87de628cef9d86b499c1386 373 PRINTS PR00143 Citrate synthase signature 169 184 1.4E-46 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 STK_05870 922befacb87de628cef9d86b499c1386 373 PRINTS PR00143 Citrate synthase signature 326 340 1.4E-46 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 STK_05870 922befacb87de628cef9d86b499c1386 373 PRINTS PR00143 Citrate synthase signature 306 322 1.4E-46 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 STK_05870 922befacb87de628cef9d86b499c1386 373 PRINTS PR00143 Citrate synthase signature 120 133 1.4E-46 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 STK_05870 922befacb87de628cef9d86b499c1386 373 PRINTS PR00143 Citrate synthase signature 191 219 1.4E-46 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 STK_05870 922befacb87de628cef9d86b499c1386 373 PRINTS PR00143 Citrate synthase signature 244 264 1.4E-46 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 STK_06130 bcea52f56b601e32e02d7788dd0123eb 133 SUPERFAMILY SSF52821 9 122 3.93E-24 T 23-10-2018 IPR036873 Rhodanese-like domain superfamily STK_06130 bcea52f56b601e32e02d7788dd0123eb 133 ProSitePatterns PS00380 Rhodanese signature 1. 43 54 - T 23-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 STK_06130 bcea52f56b601e32e02d7788dd0123eb 133 Gene3D G3DSA:3.40.250.10 20 119 2.5E-20 T 23-10-2018 IPR036873 Rhodanese-like domain superfamily STK_06130 bcea52f56b601e32e02d7788dd0123eb 133 SMART SM00450 18 113 3.5E-15 T 23-10-2018 IPR001763 Rhodanese-like domain STK_06130 bcea52f56b601e32e02d7788dd0123eb 133 Pfam PF00581 Rhodanese-like domain 25 108 4.9E-13 T 23-10-2018 IPR001763 Rhodanese-like domain STK_03680 678294675660e1ceee05d2a58c7c0d53 321 SUPERFAMILY SSF103486 6 317 9.81E-6 T 23-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 STK_03680 678294675660e1ceee05d2a58c7c0d53 321 Pfam PF01992 ATP synthase (C/AC39) subunit 9 314 2.1E-15 T 23-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 STK_15715 7f2727b8636dd9c04e75f997e1aadd62 80 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 6 43 7.0E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_15715 7f2727b8636dd9c04e75f997e1aadd62 80 SUPERFAMILY SSF89447 5 61 8.2E-11 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily STK_15715 7f2727b8636dd9c04e75f997e1aadd62 80 Gene3D G3DSA:2.10.260.10 3 44 3.2E-9 T 23-10-2018 STK_15715 7f2727b8636dd9c04e75f997e1aadd62 80 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 43 3.8E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_15715 7f2727b8636dd9c04e75f997e1aadd62 80 SMART SM00966 5 50 3.9E-9 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_08230 783b582887953d2c903ceb9a5d84e477 252 SMART SM00882 4 224 2.5E-28 T 23-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 STK_08230 783b582887953d2c903ceb9a5d84e477 252 Pfam PF01144 Coenzyme A transferase 7 209 3.8E-24 T 23-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 STK_08230 783b582887953d2c903ceb9a5d84e477 252 Gene3D G3DSA:3.30.30.40 115 154 5.1E-61 T 23-10-2018 STK_08230 783b582887953d2c903ceb9a5d84e477 252 SUPERFAMILY SSF100950 2 245 1.88E-65 T 23-10-2018 IPR037171 NagB/RpiA transferase-like STK_08230 783b582887953d2c903ceb9a5d84e477 252 Gene3D G3DSA:3.40.1080.10 5 242 5.1E-61 T 23-10-2018 STK_24030 3447308257ac4a43fad01efa54e80a1e 412 SUPERFAMILY SSF51338 1 401 3.29E-10 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_24030 3447308257ac4a43fad01efa54e80a1e 412 Gene3D G3DSA:2.30.40.10 5 394 3.0E-141 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_24030 3447308257ac4a43fad01efa54e80a1e 412 Gene3D G3DSA:3.20.20.140 47 351 3.0E-141 T 23-10-2018 STK_24030 3447308257ac4a43fad01efa54e80a1e 412 Pfam PF07969 Amidohydrolase family 102 392 1.5E-27 T 23-10-2018 IPR013108 Amidohydrolase 3 STK_24030 3447308257ac4a43fad01efa54e80a1e 412 SUPERFAMILY SSF51556 46 362 1.48E-94 T 23-10-2018 IPR032466 Metal-dependent hydrolase STK_00930 3ae41bee92512b2cc83d642664bc047d 762 Gene3D G3DSA:3.30.365.10 121 346 4.8E-85 T 23-10-2018 STK_00930 3ae41bee92512b2cc83d642664bc047d 762 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 135 705 1.9E-131 T 23-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 STK_00930 3ae41bee92512b2cc83d642664bc047d 762 Gene3D G3DSA:3.30.365.10 437 621 1.5E-85 T 23-10-2018 STK_00930 3ae41bee92512b2cc83d642664bc047d 762 Gene3D G3DSA:3.30.365.10 9 269 4.8E-85 T 23-10-2018 STK_00930 3ae41bee92512b2cc83d642664bc047d 762 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 11 120 4.0E-15 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead STK_00930 3ae41bee92512b2cc83d642664bc047d 762 SUPERFAMILY SSF54665 3 124 4.19E-30 T 23-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily STK_00930 3ae41bee92512b2cc83d642664bc047d 762 Gene3D G3DSA:3.90.1170.50 26 120 4.8E-85 T 23-10-2018 STK_00930 3ae41bee92512b2cc83d642664bc047d 762 SMART SM01008 10 120 7.5E-32 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead STK_00930 3ae41bee92512b2cc83d642664bc047d 762 Gene3D G3DSA:3.30.365.10 354 746 1.5E-85 T 23-10-2018 STK_00930 3ae41bee92512b2cc83d642664bc047d 762 SUPERFAMILY SSF56003 120 759 6.28E-143 T 23-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 STK_23640 c77031f30b33d35c19d0739d0cb7316b 1301 Pfam PF09286 Pro-kumamolisin, activation domain 39 160 7.9E-13 T 23-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 STK_23640 c77031f30b33d35c19d0739d0cb7316b 1301 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 488 498 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site STK_23640 c77031f30b33d35c19d0739d0cb7316b 1301 Gene3D G3DSA:3.40.50.200 201 573 1.3E-91 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 STK_23640 c77031f30b33d35c19d0739d0cb7316b 1301 SUPERFAMILY SSF54897 40 170 2.04E-13 T 23-10-2018 STK_23640 c77031f30b33d35c19d0739d0cb7316b 1301 PIRSF PIRSF032623 5 1300 0.0 T 23-10-2018 IPR017001 Peptidase S53, physarolisin II, archaeal-type STK_23640 c77031f30b33d35c19d0739d0cb7316b 1301 SMART SM00944 35 167 4.5E-34 T 23-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 STK_23640 c77031f30b33d35c19d0739d0cb7316b 1301 SUPERFAMILY SSF52743 210 568 9.69E-69 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 STK_04940 0e0c9946eb2c63e2bde1c198bc612c53 453 Pfam PF01266 FAD dependent oxidoreductase 7 37 1.3E-6 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 STK_04940 0e0c9946eb2c63e2bde1c198bc612c53 453 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 6 315 1.0E-56 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 STK_04940 0e0c9946eb2c63e2bde1c198bc612c53 453 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 5.1E-7 T 23-10-2018 STK_04940 0e0c9946eb2c63e2bde1c198bc612c53 453 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 5.1E-7 T 23-10-2018 STK_04940 0e0c9946eb2c63e2bde1c198bc612c53 453 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 5.1E-7 T 23-10-2018 STK_04940 0e0c9946eb2c63e2bde1c198bc612c53 453 SUPERFAMILY SSF51905 5 356 1.03E-32 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_04940 0e0c9946eb2c63e2bde1c198bc612c53 453 Gene3D G3DSA:3.50.50.60 1 452 5.4E-181 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_16670 7cd86c848a609ade39222c45bbd317e2 494 SUPERFAMILY SSF81648 212 370 1.1E-19 T 23-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 STK_16670 7cd86c848a609ade39222c45bbd317e2 494 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 87 272 2.9E-55 T 23-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 STK_16670 7cd86c848a609ade39222c45bbd317e2 494 Gene3D G3DSA:1.20.810.10 1 416 1.6E-82 T 23-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 STK_16670 7cd86c848a609ade39222c45bbd317e2 494 SUPERFAMILY SSF81342 19 251 1.96E-45 T 23-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 STK_03180 c02c0bf1b46b6902fe5ee7262a4cbcf2 384 SUPERFAMILY SSF111249 2 362 1.23E-173 T 23-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 STK_03180 c02c0bf1b46b6902fe5ee7262a4cbcf2 384 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 1 363 0.0 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 STK_03180 c02c0bf1b46b6902fe5ee7262a4cbcf2 384 Pfam PF01950 Fructose-1,6-bisphosphatase 2 362 2.8E-181 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 STK_03180 c02c0bf1b46b6902fe5ee7262a4cbcf2 384 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 1 362 59.859 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 STK_03180 c02c0bf1b46b6902fe5ee7262a4cbcf2 384 PIRSF PIRSF015647 1 373 4.7E-185 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 STK_20505 32aa0dd1fa0c81144fe3535fb3149885 54 Gene3D G3DSA:2.10.260.10 1 48 7.3E-22 T 23-10-2018 STK_20505 32aa0dd1fa0c81144fe3535fb3149885 54 SUPERFAMILY SSF89447 3 45 2.44E-11 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily STK_20505 32aa0dd1fa0c81144fe3535fb3149885 54 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 6 43 1.6E-13 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_20505 32aa0dd1fa0c81144fe3535fb3149885 54 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 45 5.7E-11 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_20505 32aa0dd1fa0c81144fe3535fb3149885 54 SMART SM00966 7 54 1.3E-10 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_03250 e8101ceaab618cf40343dba293846043 126 Pfam PF16992 DNA-directed RNA polymerase, subunit G 9 125 2.3E-49 T 23-10-2018 IPR031555 DNA-directed RNA polymerase, subunit G STK_03250 e8101ceaab618cf40343dba293846043 126 Gene3D G3DSA:2.40.50.140 1 126 2.8E-42 T 23-10-2018 STK_26060 5ca87c66eac1445be0a66632f6cdd8d4 301 Pfam PF03070 TENA/THI-4/PQQC family 68 284 9.2E-55 T 23-10-2018 IPR004305 Thiaminase-2/PQQC STK_26060 5ca87c66eac1445be0a66632f6cdd8d4 301 PIRSF PIRSF032676 1 301 3.2E-187 T 23-10-2018 IPR017004 Uncharacterised conserved protein UCP032676, PqqC STK_26060 5ca87c66eac1445be0a66632f6cdd8d4 301 SUPERFAMILY SSF48613 73 283 2.89E-39 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 STK_26060 5ca87c66eac1445be0a66632f6cdd8d4 301 Gene3D G3DSA:1.20.910.10 1 301 1.7E-132 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 STK_26060 5ca87c66eac1445be0a66632f6cdd8d4 301 Pfam PF16293 C2H2 type zinc-finger (1 copy) 1 60 5.6E-31 T 23-10-2018 IPR032553 UCP032676, C2H2 type zinc-finger domain STK_22610 cb0badf6300f6ca43a4dbd143e32bca0 112 Pfam PF01096 Transcription factor S-II (TFIIS) 72 109 1.4E-21 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 STK_22610 cb0badf6300f6ca43a4dbd143e32bca0 112 SMART SM00661 2 55 2.7E-20 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 STK_22610 cb0badf6300f6ca43a4dbd143e32bca0 112 ProSitePatterns PS01030 RNA polymerases M / 15 Kd subunits signature. 3 27 - T 23-10-2018 IPR019761 DNA-directed RNA polymerase M, 15kDa subunit, conserved site STK_22610 cb0badf6300f6ca43a4dbd143e32bca0 112 PIRSF PIRSF005586 1 112 8.1E-40 T 23-10-2018 IPR012164 DNA-directed RNA polymerase subunit/transcription factor S GO:0006351 STK_22610 cb0badf6300f6ca43a4dbd143e32bca0 112 SMART SM00440 71 110 1.6E-24 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 STK_22610 cb0badf6300f6ca43a4dbd143e32bca0 112 Gene3D G3DSA:2.20.25.10 1 38 3.9E-6 T 23-10-2018 STK_22610 cb0badf6300f6ca43a4dbd143e32bca0 112 Pfam PF02150 RNA polymerases M/15 Kd subunit 1 35 1.2E-11 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 STK_22610 cb0badf6300f6ca43a4dbd143e32bca0 112 TIGRFAM TIGR01384 TFS_arch: transcription factor S 2 112 4.3E-37 T 23-10-2018 IPR006288 Transcription factor S GO:0006355 STK_22610 cb0badf6300f6ca43a4dbd143e32bca0 112 Gene3D G3DSA:2.20.25.10 64 112 9.5E-23 T 23-10-2018 STK_22610 cb0badf6300f6ca43a4dbd143e32bca0 112 ProSitePatterns PS00466 Zinc finger TFIIS-type signature. 73 108 - T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 STK_22610 cb0badf6300f6ca43a4dbd143e32bca0 112 SUPERFAMILY SSF57783 1 37 5.1E-6 T 23-10-2018 STK_22610 cb0badf6300f6ca43a4dbd143e32bca0 112 SUPERFAMILY SSF57783 48 112 3.8E-23 T 23-10-2018 STK_06610 b105d64e194f9fd87f96784488e7403d 518 TIGRFAM TIGR00836 amt: ammonium transporter 74 484 9.4E-109 T 23-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 STK_06610 b105d64e194f9fd87f96784488e7403d 518 Pfam PF00909 Ammonium Transporter Family 75 484 2.4E-91 T 23-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 STK_06610 b105d64e194f9fd87f96784488e7403d 518 ProSitePatterns PS01219 Ammonium transporters signature. 238 263 - T 23-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 STK_06610 b105d64e194f9fd87f96784488e7403d 518 Gene3D G3DSA:1.10.3430.10 49 503 3.6E-123 T 23-10-2018 IPR029020 Ammonium/urea transporter STK_06610 b105d64e194f9fd87f96784488e7403d 518 SUPERFAMILY SSF111352 68 465 1.16E-102 T 23-10-2018 STK_06610 b105d64e194f9fd87f96784488e7403d 518 PRINTS PR00342 Rhesus blood group protein signature 307 329 4.0E-5 T 23-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 STK_06610 b105d64e194f9fd87f96784488e7403d 518 PRINTS PR00342 Rhesus blood group protein signature 276 294 4.0E-5 T 23-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 STK_06610 b105d64e194f9fd87f96784488e7403d 518 PRINTS PR00342 Rhesus blood group protein signature 396 412 4.0E-5 T 23-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 STK_06610 b105d64e194f9fd87f96784488e7403d 518 PRINTS PR00342 Rhesus blood group protein signature 182 198 4.0E-5 T 23-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 STK_04980 1d8753acfa02f314b89be1a4eb6ad7ba 320 Gene3D G3DSA:3.10.20.30 2 112 1.1E-31 T 23-10-2018 IPR012675 Beta-grasp domain superfamily STK_04980 1d8753acfa02f314b89be1a4eb6ad7ba 320 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 210 221 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_04980 1d8753acfa02f314b89be1a4eb6ad7ba 320 SUPERFAMILY SSF54292 7 112 9.7E-27 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 STK_04980 1d8753acfa02f314b89be1a4eb6ad7ba 320 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 12 117 5.1E-33 T 23-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 STK_04980 1d8753acfa02f314b89be1a4eb6ad7ba 320 Gene3D G3DSA:1.10.1060.10 113 252 5.4E-37 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 STK_04980 1d8753acfa02f314b89be1a4eb6ad7ba 320 Pfam PF13183 4Fe-4S dicluster domain 153 224 5.0E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_04980 1d8753acfa02f314b89be1a4eb6ad7ba 320 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 59 67 - T 23-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 STK_04980 1d8753acfa02f314b89be1a4eb6ad7ba 320 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 14 234 9.7E-68 T 23-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 STK_04980 1d8753acfa02f314b89be1a4eb6ad7ba 320 SUPERFAMILY SSF46548 114 238 1.41E-31 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 STK_10660 cbbbbb5e4108dee0e465aa9e2aba455f 263 Gene3D G3DSA:3.40.50.300 1 263 1.5E-64 T 23-10-2018 STK_10660 cbbbbb5e4108dee0e465aa9e2aba455f 263 SMART SM00382 29 225 6.1E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_10660 cbbbbb5e4108dee0e465aa9e2aba455f 263 Pfam PF00005 ABC transporter 21 156 1.0E-16 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_10660 cbbbbb5e4108dee0e465aa9e2aba455f 263 SUPERFAMILY SSF52540 15 191 4.99E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_14160 3f9deef369940d917e12c2698856f7a7 469 Pfam PF01409 tRNA synthetases class II core domain (F) 199 460 2.2E-83 T 23-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 STK_14160 3f9deef369940d917e12c2698856f7a7 469 Gene3D G3DSA:1.10.10.10 1 93 6.2E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_14160 3f9deef369940d917e12c2698856f7a7 469 SUPERFAMILY SSF55681 200 462 4.2E-66 T 23-10-2018 STK_14160 3f9deef369940d917e12c2698856f7a7 469 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 154 462 8.5E-95 T 23-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 STK_14160 3f9deef369940d917e12c2698856f7a7 469 Gene3D G3DSA:3.30.930.10 172 468 1.9E-92 T 23-10-2018 STK_14160 3f9deef369940d917e12c2698856f7a7 469 SUPERFAMILY SSF46785 3 72 2.2E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_14160 3f9deef369940d917e12c2698856f7a7 469 Hamap MF_00282 Phenylalanine--tRNA ligase alpha subunit [pheS]. 1 462 39.585 T 23-10-2018 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 STK_14160 3f9deef369940d917e12c2698856f7a7 469 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 2 61 1.2E-8 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal STK_22980 b2b251770559b6aa5efacfba4af518d8 305 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 197 270 1.6E-24 T 23-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal STK_22980 b2b251770559b6aa5efacfba4af518d8 305 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 10 287 1.9E-133 T 23-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate STK_22980 b2b251770559b6aa5efacfba4af518d8 305 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 44 193 8.8E-30 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 STK_22980 b2b251770559b6aa5efacfba4af518d8 305 SUPERFAMILY SSF52518 9 269 5.08E-78 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold STK_22980 b2b251770559b6aa5efacfba4af518d8 305 Gene3D G3DSA:3.40.50.970 20 197 5.2E-24 T 23-10-2018 STK_19830 3584e151e7ec809ade92e77ad95a021b 422 Gene3D G3DSA:1.10.3210.10 2 299 2.1E-68 T 23-10-2018 STK_19830 3584e151e7ec809ade92e77ad95a021b 422 SUPERFAMILY SSF109604 2 332 1.21E-69 T 23-10-2018 STK_19830 3584e151e7ec809ade92e77ad95a021b 422 Pfam PF01966 HD domain 48 186 7.3E-11 T 23-10-2018 IPR006674 HD domain STK_19830 3584e151e7ec809ade92e77ad95a021b 422 SMART SM00471 44 195 3.3E-9 T 23-10-2018 IPR003607 HD/PDEase domain STK_18740 c2f5cadd58a63511e89303b9da815508 451 Pfam PF02754 Cysteine-rich domain 244 343 1.3E-5 T 23-10-2018 IPR004017 Cysteine-rich domain STK_20100 7889891a030a957edaeb960a98dd246c 382 PIRSF PIRSF029347 14 63 1.7E-11 T 23-10-2018 IPR014555 RecF-like STK_20100 7889891a030a957edaeb960a98dd246c 382 PIRSF PIRSF029347 79 371 1.1E-11 T 23-10-2018 IPR014555 RecF-like STK_20100 7889891a030a957edaeb960a98dd246c 382 Gene3D G3DSA:3.40.50.300 15 158 7.7E-17 T 23-10-2018 STK_20100 7889891a030a957edaeb960a98dd246c 382 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 37 337 5.3E-34 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_20100 7889891a030a957edaeb960a98dd246c 382 SUPERFAMILY SSF52540 15 350 2.52E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_20100 7889891a030a957edaeb960a98dd246c 382 Gene3D G3DSA:3.40.50.300 206 360 1.4E-12 T 23-10-2018 STK_13520 6d17feaa0ae85fbd1986deecfc7293e0 411 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 339 346 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 STK_13520 6d17feaa0ae85fbd1986deecfc7293e0 411 TIGRFAM TIGR00533 HMG_CoA_R_NADP: hydroxymethylglutaryl-CoA reductase (NADPH) 6 407 2.5E-148 T 23-10-2018 IPR004554 Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type GO:0004420|GO:0008299|GO:0016021|GO:0050661|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 STK_13520 6d17feaa0ae85fbd1986deecfc7293e0 411 ProSitePatterns PS01192 Hydroxymethylglutaryl-coenzyme A reductases signature 3. 392 405 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 STK_13520 6d17feaa0ae85fbd1986deecfc7293e0 411 Gene3D G3DSA:3.30.70.420 129 243 1.1E-130 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 STK_13520 6d17feaa0ae85fbd1986deecfc7293e0 411 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 32 407 6.6E-132 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 STK_13520 6d17feaa0ae85fbd1986deecfc7293e0 411 Gene3D G3DSA:3.90.770.10 75 394 1.1E-130 T 23-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 STK_13520 6d17feaa0ae85fbd1986deecfc7293e0 411 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 224 249 5.6E-61 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 STK_13520 6d17feaa0ae85fbd1986deecfc7293e0 411 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 95 115 5.6E-61 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 STK_13520 6d17feaa0ae85fbd1986deecfc7293e0 411 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 275 301 5.6E-61 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 STK_13520 6d17feaa0ae85fbd1986deecfc7293e0 411 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 327 348 5.6E-61 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 STK_13520 6d17feaa0ae85fbd1986deecfc7293e0 411 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 184 202 5.6E-61 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 STK_13520 6d17feaa0ae85fbd1986deecfc7293e0 411 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 64 85 5.6E-61 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 STK_13520 6d17feaa0ae85fbd1986deecfc7293e0 411 SUPERFAMILY SSF55035 129 243 1.15E-44 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 STK_13520 6d17feaa0ae85fbd1986deecfc7293e0 411 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 186 200 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 STK_13520 6d17feaa0ae85fbd1986deecfc7293e0 411 SUPERFAMILY SSF56542 6 396 2.49E-86 T 23-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 STK_01160 29fcbaa3c889b2b42e24c241676074be 152 Gene3D G3DSA:3.40.50.720 1 143 1.9E-43 T 23-10-2018 STK_01160 29fcbaa3c889b2b42e24c241676074be 152 Pfam PF13380 CoA binding domain 16 135 4.0E-38 T 23-10-2018 IPR003781 CoA-binding GO:0048037 STK_01160 29fcbaa3c889b2b42e24c241676074be 152 SUPERFAMILY SSF51735 5 136 1.29E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_01160 29fcbaa3c889b2b42e24c241676074be 152 SMART SM00881 12 109 8.8E-26 T 23-10-2018 IPR003781 CoA-binding GO:0048037 STK_16170 e926cd9d5edbf820e772f71a0e8eafd1 438 Gene3D G3DSA:3.40.1380.20 316 438 4.1E-26 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 STK_16170 e926cd9d5edbf820e772f71a0e8eafd1 438 SUPERFAMILY SSF50800 61 147 2.27E-15 T 23-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily STK_16170 e926cd9d5edbf820e772f71a0e8eafd1 438 Pfam PF02887 Pyruvate kinase, alpha/beta domain 328 435 9.6E-20 T 23-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 STK_16170 e926cd9d5edbf820e772f71a0e8eafd1 438 PRINTS PR01050 Pyruvate kinase family signature 289 305 7.8E-53 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 STK_16170 e926cd9d5edbf820e772f71a0e8eafd1 438 PRINTS PR01050 Pyruvate kinase family signature 50 66 7.8E-53 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 STK_16170 e926cd9d5edbf820e772f71a0e8eafd1 438 PRINTS PR01050 Pyruvate kinase family signature 193 219 7.8E-53 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 STK_16170 e926cd9d5edbf820e772f71a0e8eafd1 438 PRINTS PR01050 Pyruvate kinase family signature 270 288 7.8E-53 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 STK_16170 e926cd9d5edbf820e772f71a0e8eafd1 438 PRINTS PR01050 Pyruvate kinase family signature 220 244 7.8E-53 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 STK_16170 e926cd9d5edbf820e772f71a0e8eafd1 438 PRINTS PR01050 Pyruvate kinase family signature 166 180 7.8E-53 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 STK_16170 e926cd9d5edbf820e772f71a0e8eafd1 438 PRINTS PR01050 Pyruvate kinase family signature 245 269 7.8E-53 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 STK_16170 e926cd9d5edbf820e772f71a0e8eafd1 438 Pfam PF00224 Pyruvate kinase, barrel domain 3 315 4.7E-80 T 23-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 STK_16170 e926cd9d5edbf820e772f71a0e8eafd1 438 Gene3D G3DSA:2.40.33.10 61 148 3.6E-98 T 23-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 STK_16170 e926cd9d5edbf820e772f71a0e8eafd1 438 SUPERFAMILY SSF51621 1 314 8.72E-74 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 STK_16170 e926cd9d5edbf820e772f71a0e8eafd1 438 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 437 7.8E-120 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 STK_16170 e926cd9d5edbf820e772f71a0e8eafd1 438 ProSitePatterns PS00110 Pyruvate kinase active site signature. 191 203 - T 23-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 STK_16170 e926cd9d5edbf820e772f71a0e8eafd1 438 Gene3D G3DSA:3.20.20.60 6 305 3.6E-98 T 23-10-2018 STK_16170 e926cd9d5edbf820e772f71a0e8eafd1 438 SUPERFAMILY SSF52935 299 436 8.5E-27 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 STK_05610 b8643b2117f99a5ced92eaad0caadd30 168 Gene3D G3DSA:1.10.150.120 85 168 1.2E-39 T 23-10-2018 STK_05610 b8643b2117f99a5ced92eaad0caadd30 168 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 15 67 1.3E-7 T 23-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 STK_05610 b8643b2117f99a5ced92eaad0caadd30 168 Pfam PF01799 [2Fe-2S] binding domain 81 154 2.7E-34 T 23-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 STK_05610 b8643b2117f99a5ced92eaad0caadd30 168 SUPERFAMILY SSF47741 92 162 2.75E-36 T 23-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily STK_05610 b8643b2117f99a5ced92eaad0caadd30 168 Gene3D G3DSA:3.10.20.30 1 84 7.6E-34 T 23-10-2018 IPR012675 Beta-grasp domain superfamily STK_05610 b8643b2117f99a5ced92eaad0caadd30 168 SUPERFAMILY SSF54292 8 95 1.31E-23 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 STK_12350 ce22e43ac5ea9c81098a63176e3af195 784 Pfam PF00391 PEP-utilising enzyme, mobile domain 373 444 2.3E-28 T 23-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 STK_12350 ce22e43ac5ea9c81098a63176e3af195 784 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 23 337 3.4E-113 T 23-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 STK_12350 ce22e43ac5ea9c81098a63176e3af195 784 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 676 694 - T 23-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 STK_12350 ce22e43ac5ea9c81098a63176e3af195 784 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 471 773 3.1E-81 T 23-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 STK_12350 ce22e43ac5ea9c81098a63176e3af195 784 PIRSF PIRSF000854 6 778 9.1E-258 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 STK_12350 ce22e43ac5ea9c81098a63176e3af195 784 SUPERFAMILY SSF56059 9 370 4.0E-103 T 23-10-2018 STK_12350 ce22e43ac5ea9c81098a63176e3af195 784 SUPERFAMILY SSF52009 342 452 7.19E-38 T 23-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 STK_12350 ce22e43ac5ea9c81098a63176e3af195 784 Gene3D G3DSA:3.50.30.10 346 453 7.4E-45 T 23-10-2018 STK_12350 ce22e43ac5ea9c81098a63176e3af195 784 Gene3D G3DSA:3.20.20.60 480 773 5.5E-92 T 23-10-2018 STK_12350 ce22e43ac5ea9c81098a63176e3af195 784 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 403 414 - T 23-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 STK_12350 ce22e43ac5ea9c81098a63176e3af195 784 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 11 774 0.0 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 STK_12350 ce22e43ac5ea9c81098a63176e3af195 784 SUPERFAMILY SSF51621 473 779 4.71E-93 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 STK_12350 ce22e43ac5ea9c81098a63176e3af195 784 Gene3D G3DSA:3.30.470.20 189 345 3.2E-50 T 23-10-2018 STK_12350 ce22e43ac5ea9c81098a63176e3af195 784 Gene3D G3DSA:3.30.1490.20 7 188 2.7E-65 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 STK_20900 fcf04d2938a453526ca4fb873b95c19f 318 SUPERFAMILY SSF89733 2 314 4.32E-68 T 23-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 STK_20900 fcf04d2938a453526ca4fb873b95c19f 318 Pfam PF02615 Malate/L-lactate dehydrogenase 3 259 1.4E-62 T 23-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 STK_20900 fcf04d2938a453526ca4fb873b95c19f 318 Gene3D G3DSA:3.30.60.50 167 214 1.1E-58 T 23-10-2018 STK_20900 fcf04d2938a453526ca4fb873b95c19f 318 Gene3D G3DSA:3.30.1370.60 59 259 1.1E-58 T 23-10-2018 STK_20900 fcf04d2938a453526ca4fb873b95c19f 318 Gene3D G3DSA:1.10.1530.10 10 58 1.1E-58 T 23-10-2018 STK_14450 8821e44565e22d02e897e8c68c26b49b 332 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 324 2.3E-124 T 23-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 STK_14450 8821e44565e22d02e897e8c68c26b49b 332 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 324 2.2E-54 T 23-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 STK_14450 8821e44565e22d02e897e8c68c26b49b 332 SUPERFAMILY SSF51735 3 183 2.19E-70 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_14450 8821e44565e22d02e897e8c68c26b49b 332 SUPERFAMILY SSF48179 184 324 2.04E-58 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 STK_14450 8821e44565e22d02e897e8c68c26b49b 332 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 178 2.0E-72 T 23-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 STK_14450 8821e44565e22d02e897e8c68c26b49b 332 Gene3D G3DSA:3.40.50.720 1 182 1.9E-72 T 23-10-2018 STK_14450 8821e44565e22d02e897e8c68c26b49b 332 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 329 39.082 T 23-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 STK_14450 8821e44565e22d02e897e8c68c26b49b 332 PIRSF PIRSF000116 4 207 5.4E-39 T 23-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 STK_14450 8821e44565e22d02e897e8c68c26b49b 332 PIRSF PIRSF000116 199 327 1.9E-9 T 23-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 STK_14450 8821e44565e22d02e897e8c68c26b49b 332 Gene3D G3DSA:1.10.3730.40 183 329 7.5E-58 T 23-10-2018 STK_18650 b962587371072b7ffcb39c5a538cae14 412 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 287 1.9E-48 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 STK_18650 b962587371072b7ffcb39c5a538cae14 412 Gene3D G3DSA:3.30.390.30 300 410 2.2E-21 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 STK_18650 b962587371072b7ffcb39c5a538cae14 412 SUPERFAMILY SSF55424 305 408 4.3E-21 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 STK_18650 b962587371072b7ffcb39c5a538cae14 412 SUPERFAMILY SSF51905 2 323 3.16E-39 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_18650 b962587371072b7ffcb39c5a538cae14 412 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 1.2E-24 T 23-10-2018 STK_18650 b962587371072b7ffcb39c5a538cae14 412 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 1.2E-24 T 23-10-2018 STK_18650 b962587371072b7ffcb39c5a538cae14 412 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 2 21 1.2E-24 T 23-10-2018 STK_18650 b962587371072b7ffcb39c5a538cae14 412 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 120 138 1.2E-24 T 23-10-2018 STK_18650 b962587371072b7ffcb39c5a538cae14 412 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 276 1.2E-24 T 23-10-2018 STK_18650 b962587371072b7ffcb39c5a538cae14 412 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 307 404 1.5E-13 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 STK_18650 b962587371072b7ffcb39c5a538cae14 412 Gene3D G3DSA:3.50.50.60 2 291 2.2E-64 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_18650 b962587371072b7ffcb39c5a538cae14 412 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 35 45 - T 23-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 STK_18650 b962587371072b7ffcb39c5a538cae14 412 Gene3D G3DSA:3.50.50.60 132 238 2.2E-64 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_18650 b962587371072b7ffcb39c5a538cae14 412 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 1 22 1.5E-38 T 23-10-2018 STK_18650 b962587371072b7ffcb39c5a538cae14 412 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 232 246 1.5E-38 T 23-10-2018 STK_18650 b962587371072b7ffcb39c5a538cae14 412 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 177 1.5E-38 T 23-10-2018 STK_18650 b962587371072b7ffcb39c5a538cae14 412 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 34 49 1.5E-38 T 23-10-2018 STK_18650 b962587371072b7ffcb39c5a538cae14 412 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 380 400 1.5E-38 T 23-10-2018 STK_18650 b962587371072b7ffcb39c5a538cae14 412 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 303 324 1.5E-38 T 23-10-2018 STK_06115 d4a5a16aac325cc16ba5681eab968c90 79 TIGRFAM TIGR02174 CXXU_selWTH: selT/selW/selH selenoprotein domain 4 73 1.6E-18 T 23-10-2018 IPR011893 Selenoprotein, Rdx-type STK_06115 d4a5a16aac325cc16ba5681eab968c90 79 Pfam PF10262 Rdx family 4 72 4.5E-20 T 23-10-2018 IPR011893 Selenoprotein, Rdx-type STK_06115 d4a5a16aac325cc16ba5681eab968c90 79 SUPERFAMILY SSF52833 2 74 5.59E-19 T 23-10-2018 IPR036249 Thioredoxin-like superfamily STK_06115 d4a5a16aac325cc16ba5681eab968c90 79 Gene3D G3DSA:3.40.30.10 1 76 1.8E-26 T 23-10-2018 STK_05730 80bc3f2ef16b4851e4988e42f32e0f62 351 Gene3D G3DSA:3.30.1490.100 244 340 5.6E-27 T 23-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 STK_05730 80bc3f2ef16b4851e4988e42f32e0f62 351 Pfam PF11798 IMS family HHH motif 168 199 1.1E-6 T 23-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 STK_05730 80bc3f2ef16b4851e4988e42f32e0f62 351 Gene3D G3DSA:3.30.70.270 74 166 7.9E-31 T 23-10-2018 STK_05730 80bc3f2ef16b4851e4988e42f32e0f62 351 SUPERFAMILY SSF100879 239 341 3.66E-26 T 23-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 STK_05730 80bc3f2ef16b4851e4988e42f32e0f62 351 SUPERFAMILY SSF56672 1 233 3.29E-68 T 23-10-2018 STK_05730 80bc3f2ef16b4851e4988e42f32e0f62 351 Gene3D G3DSA:2.30.40.20 11 73 5.1E-30 T 23-10-2018 STK_05730 80bc3f2ef16b4851e4988e42f32e0f62 351 Pfam PF00817 impB/mucB/samB family 6 155 5.4E-45 T 23-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 STK_05730 80bc3f2ef16b4851e4988e42f32e0f62 351 Hamap MF_01113 DNA polymerase IV [dinB]. 1 347 28.176 T 23-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 STK_05730 80bc3f2ef16b4851e4988e42f32e0f62 351 Gene3D G3DSA:1.10.150.20 167 233 2.6E-23 T 23-10-2018 STK_09620 79a9cf7924612c544ae17cb1dcd2423a 259 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 209 222 - T 23-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site STK_09620 79a9cf7924612c544ae17cb1dcd2423a 259 Gene3D G3DSA:3.40.50.261 97 259 3.0E-63 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 STK_09620 79a9cf7924612c544ae17cb1dcd2423a 259 SUPERFAMILY SSF51735 1 95 1.63E-31 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_09620 79a9cf7924612c544ae17cb1dcd2423a 259 Gene3D G3DSA:3.40.50.720 1 96 4.0E-40 T 23-10-2018 STK_09620 79a9cf7924612c544ae17cb1dcd2423a 259 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 1 257 7.7E-107 T 23-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 STK_09620 79a9cf7924612c544ae17cb1dcd2423a 259 PIRSF PIRSF001553 1 259 8.3E-117 T 23-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 STK_09620 79a9cf7924612c544ae17cb1dcd2423a 259 PRINTS PR01798 Succinyl-CoA synthase signature 213 230 1.6E-29 T 23-10-2018 STK_09620 79a9cf7924612c544ae17cb1dcd2423a 259 PRINTS PR01798 Succinyl-CoA synthase signature 55 72 1.6E-29 T 23-10-2018 STK_09620 79a9cf7924612c544ae17cb1dcd2423a 259 PRINTS PR01798 Succinyl-CoA synthase signature 180 193 1.6E-29 T 23-10-2018 STK_09620 79a9cf7924612c544ae17cb1dcd2423a 259 PRINTS PR01798 Succinyl-CoA synthase signature 149 167 1.6E-29 T 23-10-2018 STK_09620 79a9cf7924612c544ae17cb1dcd2423a 259 SUPERFAMILY SSF52210 96 257 3.14E-44 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 STK_09620 79a9cf7924612c544ae17cb1dcd2423a 259 SMART SM00881 1 73 6.7E-11 T 23-10-2018 IPR003781 CoA-binding GO:0048037 STK_09620 79a9cf7924612c544ae17cb1dcd2423a 259 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 259 32.972 T 23-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 STK_09620 79a9cf7924612c544ae17cb1dcd2423a 259 Pfam PF02629 CoA binding domain 1 72 1.6E-21 T 23-10-2018 IPR003781 CoA-binding GO:0048037 STK_09620 79a9cf7924612c544ae17cb1dcd2423a 259 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 125 153 - T 23-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site STK_09620 79a9cf7924612c544ae17cb1dcd2423a 259 Pfam PF00549 CoA-ligase 124 243 1.7E-14 T 23-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 STK_12650 ab4ff66662f87a97bf56da78d123eb84 409 SMART SM00931 138 190 1.6E-28 T 23-10-2018 IPR012976 NOSIC STK_12650 ab4ff66662f87a97bf56da78d123eb84 409 Gene3D G3DSA:3.30.420.220 1 106 1.2E-49 T 23-10-2018 STK_12650 ab4ff66662f87a97bf56da78d123eb84 409 Pfam PF01798 snoRNA binding domain, fibrillarin 146 371 2.1E-75 T 23-10-2018 IPR002687 Nop domain STK_12650 ab4ff66662f87a97bf56da78d123eb84 409 Gene3D G3DSA:1.10.150.460 169 220 1.7E-39 T 23-10-2018 STK_12650 ab4ff66662f87a97bf56da78d123eb84 409 Gene3D G3DSA:1.10.246.90 252 376 2.0E-51 T 23-10-2018 STK_12650 ab4ff66662f87a97bf56da78d123eb84 409 SUPERFAMILY SSF89124 133 373 3.14E-81 T 23-10-2018 IPR036070 Nop domain superfamily STK_12650 ab4ff66662f87a97bf56da78d123eb84 409 Gene3D G3DSA:1.10.287.660 139 251 1.7E-39 T 23-10-2018 IPR029012 Helix hairpin bin domain superfamily STK_14660 5f3f2564282170b78f63e486a1d068d5 196 PIRSF PIRSF000495 1 196 7.5E-56 T 23-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 STK_14660 5f3f2564282170b78f63e486a1d068d5 196 Gene3D G3DSA:3.40.50.880 2 196 2.2E-52 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_14660 5f3f2564282170b78f63e486a1d068d5 196 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 2 193 29.706 T 23-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 STK_14660 5f3f2564282170b78f63e486a1d068d5 196 SUPERFAMILY SSF52317 4 194 2.14E-39 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_14660 5f3f2564282170b78f63e486a1d068d5 196 Pfam PF00117 Glutamine amidotransferase class-I 21 190 2.5E-19 T 23-10-2018 IPR017926 Glutamine amidotransferase STK_14660 5f3f2564282170b78f63e486a1d068d5 196 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 192 1.2E-60 T 23-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 STK_22930 4606e3ae49679b4a4c90f8fe09df0c9a 221 Pfam PF13614 AAA domain 2 152 3.8E-30 T 23-10-2018 IPR025669 AAA domain STK_22930 4606e3ae49679b4a4c90f8fe09df0c9a 221 SUPERFAMILY SSF52540 1 217 4.71E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_22930 4606e3ae49679b4a4c90f8fe09df0c9a 221 Gene3D G3DSA:3.40.50.300 1 221 7.7E-41 T 23-10-2018 STK_12160 2a947c33eac5c3ea4124050ed8be76bd 664 Gene3D G3DSA:1.10.460.10 164 572 2.0E-90 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 STK_12160 2a947c33eac5c3ea4124050ed8be76bd 664 Pfam PF01751 Toprim domain 10 139 3.3E-14 T 23-10-2018 IPR006171 TOPRIM domain STK_12160 2a947c33eac5c3ea4124050ed8be76bd 664 Pfam PF01131 DNA topoisomerase 156 564 9.3E-110 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 STK_12160 2a947c33eac5c3ea4124050ed8be76bd 664 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 306 320 - T 23-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 STK_12160 2a947c33eac5c3ea4124050ed8be76bd 664 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 490 504 4.6E-19 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 STK_12160 2a947c33eac5c3ea4124050ed8be76bd 664 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 389 405 4.6E-19 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 STK_12160 2a947c33eac5c3ea4124050ed8be76bd 664 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 105 118 4.6E-19 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 STK_12160 2a947c33eac5c3ea4124050ed8be76bd 664 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 195 213 4.6E-19 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 STK_12160 2a947c33eac5c3ea4124050ed8be76bd 664 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 311 320 4.6E-19 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 STK_12160 2a947c33eac5c3ea4124050ed8be76bd 664 SMART SM00493 8 131 5.4E-5 T 23-10-2018 IPR006171 TOPRIM domain STK_12160 2a947c33eac5c3ea4124050ed8be76bd 664 TIGRFAM TIGR01057 topA_arch: DNA topoisomerase I 12 605 8.0E-177 T 23-10-2018 IPR005739 DNA topoisomerase I, archeal-type GO:0003677|GO:0003916|GO:0006265 STK_12160 2a947c33eac5c3ea4124050ed8be76bd 664 SMART SM00436 131 225 2.5E-27 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 STK_12160 2a947c33eac5c3ea4124050ed8be76bd 664 Gene3D G3DSA:3.40.50.140 2 154 8.0E-25 T 23-10-2018 STK_12160 2a947c33eac5c3ea4124050ed8be76bd 664 SUPERFAMILY SSF56712 9 605 5.23E-132 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain STK_12160 2a947c33eac5c3ea4124050ed8be76bd 664 Gene3D G3DSA:2.70.20.10 219 473 2.0E-90 T 23-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 STK_12160 2a947c33eac5c3ea4124050ed8be76bd 664 SMART SM00437 269 527 6.3E-55 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 STK_12160 2a947c33eac5c3ea4124050ed8be76bd 664 Gene3D G3DSA:1.10.290.10 277 403 2.0E-90 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 STK_05700 04cd057832997752e82194a9d4517743 339 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 2 324 2.7E-132 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 STK_05700 04cd057832997752e82194a9d4517743 339 ProSitePatterns PS01287 RNA 3'-terminal phosphate cyclase signature. 153 163 - T 23-10-2018 IPR020719 RNA 3'-terminal phosphate cyclase-like, conserved site STK_05700 04cd057832997752e82194a9d4517743 339 Pfam PF01137 RNA 3'-terminal phosphate cyclase 9 325 2.2E-76 T 23-10-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain STK_05700 04cd057832997752e82194a9d4517743 339 SUPERFAMILY SSF55205 1 230 2.48E-62 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 STK_05700 04cd057832997752e82194a9d4517743 339 PIRSF PIRSF005378 1 334 5.7E-108 T 23-10-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 STK_05700 04cd057832997752e82194a9d4517743 339 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 1 330 38.853 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 STK_05700 04cd057832997752e82194a9d4517743 339 Gene3D G3DSA:3.30.360.20 180 275 3.7E-112 T 23-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily STK_05700 04cd057832997752e82194a9d4517743 339 Gene3D G3DSA:3.65.10.20 3 319 3.7E-112 T 23-10-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily STK_05700 04cd057832997752e82194a9d4517743 339 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 179 274 6.8E-21 T 23-10-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain STK_06580 ecd2522b4f7940bf2c88d65c30583fc1 101 SUPERFAMILY SSF46785 10 96 6.7E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_06580 ecd2522b4f7940bf2c88d65c30583fc1 101 Gene3D G3DSA:1.10.10.10 4 101 3.2E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_06580 ecd2522b4f7940bf2c88d65c30583fc1 101 Pfam PF14947 Winged helix-turn-helix 10 84 7.0E-29 T 23-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain STK_17060 dec7c30024e685314afc7b4faeaebe94 366 SMART SM00382 12 211 0.04 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_17060 dec7c30024e685314afc7b4faeaebe94 366 SMART SM00382 223 365 2.8E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_17060 dec7c30024e685314afc7b4faeaebe94 366 Pfam PF00005 ABC transporter 8 135 2.4E-14 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_17060 dec7c30024e685314afc7b4faeaebe94 366 Pfam PF00005 ABC transporter 255 317 8.6E-8 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_17060 dec7c30024e685314afc7b4faeaebe94 366 Gene3D G3DSA:3.40.50.300 4 194 1.3E-27 T 23-10-2018 STK_17060 dec7c30024e685314afc7b4faeaebe94 366 Gene3D G3DSA:3.40.50.300 253 366 4.8E-21 T 23-10-2018 STK_17060 dec7c30024e685314afc7b4faeaebe94 366 ProSitePatterns PS00211 ABC transporters family signature. 290 304 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 STK_17060 dec7c30024e685314afc7b4faeaebe94 366 SUPERFAMILY SSF52540 8 181 1.9E-26 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_17060 dec7c30024e685314afc7b4faeaebe94 366 Gene3D G3DSA:3.40.50.300 195 252 2.4E-5 T 23-10-2018 STK_17060 dec7c30024e685314afc7b4faeaebe94 366 SUPERFAMILY SSF52540 213 364 7.2E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_12640 fa1115a1947a10c977a9dd330fdcc663 448 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 92 429 1.1E-124 T 23-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 STK_12640 fa1115a1947a10c977a9dd330fdcc663 448 Gene3D G3DSA:3.40.50.1170 84 302 1.3E-72 T 23-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 STK_12640 fa1115a1947a10c977a9dd330fdcc663 448 Pfam PF00710 Asparaginase, N-terminal 94 288 1.3E-60 T 23-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 STK_12640 fa1115a1947a10c977a9dd330fdcc663 448 SUPERFAMILY SSF141300 4 73 1.31E-20 T 23-10-2018 IPR037222 GatD, N-terminal STK_12640 fa1115a1947a10c977a9dd330fdcc663 448 PIRSF PIRSF001220 88 428 1.9E-135 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 STK_12640 fa1115a1947a10c977a9dd330fdcc663 448 TIGRFAM TIGR02153 gatD_arch: glutamyl-tRNA(Gln) amidotransferase, subunit D 33 433 1.3E-191 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 STK_12640 fa1115a1947a10c977a9dd330fdcc663 448 Gene3D G3DSA:2.30.30.520 3 83 4.7E-21 T 23-10-2018 IPR037222 GatD, N-terminal STK_12640 fa1115a1947a10c977a9dd330fdcc663 448 PRINTS PR00139 Asparaginase/glutaminase family signature 170 188 5.5E-15 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 STK_12640 fa1115a1947a10c977a9dd330fdcc663 448 PRINTS PR00139 Asparaginase/glutaminase family signature 94 105 5.5E-15 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 STK_12640 fa1115a1947a10c977a9dd330fdcc663 448 PRINTS PR00139 Asparaginase/glutaminase family signature 354 372 5.5E-15 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 STK_12640 fa1115a1947a10c977a9dd330fdcc663 448 Gene3D G3DSA:3.40.50.40 303 438 9.4E-49 T 23-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 STK_12640 fa1115a1947a10c977a9dd330fdcc663 448 Hamap MF_00586 Glutamyl-tRNA(Gln) amidotransferase subunit D [gatD]. 24 433 46.67 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 STK_12640 fa1115a1947a10c977a9dd330fdcc663 448 SUPERFAMILY SSF53774 88 437 1.06E-107 T 23-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 STK_12640 fa1115a1947a10c977a9dd330fdcc663 448 SMART SM00870 93 417 1.5E-137 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 STK_12640 fa1115a1947a10c977a9dd330fdcc663 448 PIRSF PIRSF500175 18 437 1.2E-189 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 STK_12640 fa1115a1947a10c977a9dd330fdcc663 448 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 171 181 - T 23-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 STK_17970 ce3725920b253af4192cfb8c660045fa 142 Gene3D G3DSA:1.10.12.20 1 75 2.1E-32 T 23-10-2018 STK_17970 ce3725920b253af4192cfb8c660045fa 142 SUPERFAMILY SSF50249 11 135 7.54E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_17970 ce3725920b253af4192cfb8c660045fa 142 Gene3D G3DSA:2.40.50.140 76 142 3.2E-35 T 23-10-2018 STK_17970 ce3725920b253af4192cfb8c660045fa 142 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 73 130 1.5E-6 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal STK_17970 ce3725920b253af4192cfb8c660045fa 142 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 36 70 5.4E-10 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal STK_10140 730de31def22d7c857a8a8c11af0a136 355 SUPERFAMILY SSF51556 9 294 1.84E-62 T 23-10-2018 IPR032466 Metal-dependent hydrolase STK_10140 730de31def22d7c857a8a8c11af0a136 355 Gene3D G3DSA:2.30.40.10 6 328 2.1E-68 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_10140 730de31def22d7c857a8a8c11af0a136 355 Pfam PF01979 Amidohydrolase family 5 268 4.7E-6 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 STK_10140 730de31def22d7c857a8a8c11af0a136 355 Gene3D G3DSA:3.20.20.140 9 292 2.1E-68 T 23-10-2018 STK_05570 b81c2ae13c6697b33bb98fb4681bc99f 525 SUPERFAMILY SSF50465 436 524 7.67E-19 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal STK_05570 b81c2ae13c6697b33bb98fb4681bc99f 525 Gene3D G3DSA:3.40.50.300 106 336 9.0E-36 T 23-10-2018 STK_05570 b81c2ae13c6697b33bb98fb4681bc99f 525 Pfam PF00009 Elongation factor Tu GTP binding domain 112 329 4.3E-22 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_05570 b81c2ae13c6697b33bb98fb4681bc99f 525 SUPERFAMILY SSF52540 111 362 3.36E-32 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_05570 b81c2ae13c6697b33bb98fb4681bc99f 525 SUPERFAMILY SSF50447 341 434 4.86E-16 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily STK_05570 b81c2ae13c6697b33bb98fb4681bc99f 525 Gene3D G3DSA:2.40.30.10 437 523 2.8E-8 T 23-10-2018 STK_05570 b81c2ae13c6697b33bb98fb4681bc99f 525 Gene3D G3DSA:2.40.30.10 342 436 3.8E-18 T 23-10-2018 STK_05570 b81c2ae13c6697b33bb98fb4681bc99f 525 Pfam PF03143 Elongation factor Tu C-terminal domain 437 489 7.2E-8 T 23-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal STK_25075 45abd65005c2d3e07862424d2088c7f9 68 Gene3D G3DSA:1.10.10.10 3 68 1.1E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_25075 45abd65005c2d3e07862424d2088c7f9 68 Pfam PF14947 Winged helix-turn-helix 23 67 2.4E-7 T 23-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain STK_25075 45abd65005c2d3e07862424d2088c7f9 68 SUPERFAMILY SSF46785 5 67 8.73E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_23185 4d194595f53b41f92ccdc9c88d8f69bd 65 SUPERFAMILY SSF46785 11 63 4.53E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_23185 4d194595f53b41f92ccdc9c88d8f69bd 65 Gene3D G3DSA:1.10.10.10 2 59 2.9E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_05260 838eb6e0ec515c424f40479cf7e10596 448 Pfam PF10120 Thiamine-phosphate synthase 273 440 1.0E-47 T 23-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 STK_05260 838eb6e0ec515c424f40479cf7e10596 448 SUPERFAMILY SSF53639 265 443 2.0E-50 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily STK_05260 838eb6e0ec515c424f40479cf7e10596 448 Gene3D G3DSA:3.40.225.10 262 446 2.3E-49 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily STK_05260 838eb6e0ec515c424f40479cf7e10596 448 Gene3D G3DSA:3.40.1190.20 1 259 3.4E-63 T 23-10-2018 IPR029056 Ribokinase-like STK_05260 838eb6e0ec515c424f40479cf7e10596 448 Pfam PF08543 Phosphomethylpyrimidine kinase 13 255 3.2E-71 T 23-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 STK_05260 838eb6e0ec515c424f40479cf7e10596 448 SUPERFAMILY SSF53613 6 260 4.52E-56 T 23-10-2018 IPR029056 Ribokinase-like STK_05260 838eb6e0ec515c424f40479cf7e10596 448 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 255 4.5E-72 T 23-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 STK_23050 91e419b038d9cb405c7834078dfd5718 350 PRINTS PR01270 Histone deacetylase superfamily signature 120 143 2.2E-17 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 STK_23050 91e419b038d9cb405c7834078dfd5718 350 PRINTS PR01270 Histone deacetylase superfamily signature 238 248 2.2E-17 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 STK_23050 91e419b038d9cb405c7834078dfd5718 350 PRINTS PR01270 Histone deacetylase superfamily signature 152 167 2.2E-17 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 STK_23050 91e419b038d9cb405c7834078dfd5718 350 Pfam PF00850 Histone deacetylase domain 27 305 1.4E-75 T 23-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 STK_23050 91e419b038d9cb405c7834078dfd5718 350 PRINTS PR01272 Acetoin utilisation ACUC protein signature 99 112 9.4E-6 T 23-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 STK_23050 91e419b038d9cb405c7834078dfd5718 350 PRINTS PR01272 Acetoin utilisation ACUC protein signature 263 279 9.4E-6 T 23-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 STK_23050 91e419b038d9cb405c7834078dfd5718 350 PRINTS PR01272 Acetoin utilisation ACUC protein signature 15 35 9.4E-6 T 23-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 STK_23050 91e419b038d9cb405c7834078dfd5718 350 Gene3D G3DSA:3.40.800.20 1 346 1.5E-101 T 23-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 STK_23050 91e419b038d9cb405c7834078dfd5718 350 SUPERFAMILY SSF52768 3 333 2.88E-101 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily STK_10990 ffa2a219a20650ec03c34fff9f55e597 851 Gene3D G3DSA:1.20.1560.10 91 433 1.2E-86 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 STK_10990 ffa2a219a20650ec03c34fff9f55e597 851 SMART SM00382 470 656 2.6E-18 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_10990 ffa2a219a20650ec03c34fff9f55e597 851 Pfam PF00664 ABC transporter transmembrane region 127 399 1.5E-46 T 23-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 STK_10990 ffa2a219a20650ec03c34fff9f55e597 851 SUPERFAMILY SSF52540 436 680 9.32E-86 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_10990 ffa2a219a20650ec03c34fff9f55e597 851 Pfam PF00005 ABC transporter 462 610 9.0E-36 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_10990 ffa2a219a20650ec03c34fff9f55e597 851 Gene3D G3DSA:3.40.50.300 440 693 5.0E-89 T 23-10-2018 STK_10990 ffa2a219a20650ec03c34fff9f55e597 851 SUPERFAMILY SSF90123 114 433 1.57E-78 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 STK_10990 ffa2a219a20650ec03c34fff9f55e597 851 ProSitePatterns PS00211 ABC transporters family signature. 582 596 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 STK_10990 ffa2a219a20650ec03c34fff9f55e597 851 Pfam PF08909 Domain of unknown function (DUF1854) 724 849 3.1E-34 T 23-10-2018 IPR015005 Domain of unknown function DUF1854 STK_10400 e752265ab5f4fc7b9394a3202c7e36ce 419 SUPERFAMILY SSF160980 34 410 6.54E-28 T 23-10-2018 STK_10400 e752265ab5f4fc7b9394a3202c7e36ce 419 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 7 383 2.1E-29 T 23-10-2018 IPR019016 CRISPR-associated DxTHG protein STK_11140 6d4d522eb18f301d5e8d2c799566cca8 441 Gene3D G3DSA:3.90.1150.10 10 430 1.1E-154 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 STK_11140 6d4d522eb18f301d5e8d2c799566cca8 441 Gene3D G3DSA:3.40.640.10 59 323 1.1E-154 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 STK_11140 6d4d522eb18f301d5e8d2c799566cca8 441 PIRSF PIRSF000521 122 435 1.1E-26 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 STK_11140 6d4d522eb18f301d5e8d2c799566cca8 441 PIRSF PIRSF000521 25 130 4.0E-13 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 STK_11140 6d4d522eb18f301d5e8d2c799566cca8 441 Pfam PF00202 Aminotransferase class-III 24 432 4.4E-96 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 STK_11140 6d4d522eb18f301d5e8d2c799566cca8 441 SUPERFAMILY SSF53383 2 434 5.77E-113 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase STK_12120 d12f88acd26f2cc42733a7aea32bb3cb 416 Gene3D G3DSA:3.20.20.120 125 415 1.6E-111 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily STK_12120 d12f88acd26f2cc42733a7aea32bb3cb 416 Pfam PF00113 Enolase, C-terminal TIM barrel domain 138 411 7.0E-96 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 STK_12120 d12f88acd26f2cc42733a7aea32bb3cb 416 Gene3D G3DSA:3.30.390.10 5 124 3.3E-37 T 23-10-2018 IPR029017 Enolase-like, N-terminal STK_12120 d12f88acd26f2cc42733a7aea32bb3cb 416 SUPERFAMILY SSF51604 137 405 5.09E-100 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily STK_12120 d12f88acd26f2cc42733a7aea32bb3cb 416 SMART SM01193 7 131 1.8E-55 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 STK_12120 d12f88acd26f2cc42733a7aea32bb3cb 416 ProSitePatterns PS00164 Enolase signature. 328 341 - T 23-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_12120 d12f88acd26f2cc42733a7aea32bb3cb 416 PRINTS PR00148 Enolase signature 40 54 6.5E-33 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 STK_12120 d12f88acd26f2cc42733a7aea32bb3cb 416 PRINTS PR00148 Enolase signature 357 374 6.5E-33 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 STK_12120 d12f88acd26f2cc42733a7aea32bb3cb 416 PRINTS PR00148 Enolase signature 104 120 6.5E-33 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 STK_12120 d12f88acd26f2cc42733a7aea32bb3cb 416 PRINTS PR00148 Enolase signature 328 342 6.5E-33 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 STK_12120 d12f88acd26f2cc42733a7aea32bb3cb 416 PRINTS PR00148 Enolase signature 158 171 6.5E-33 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 STK_12120 d12f88acd26f2cc42733a7aea32bb3cb 416 PRINTS PR00148 Enolase signature 305 316 6.5E-33 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 STK_12120 d12f88acd26f2cc42733a7aea32bb3cb 416 SMART SM01192 136 416 2.1E-147 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 STK_12120 d12f88acd26f2cc42733a7aea32bb3cb 416 PIRSF PIRSF001400 3 415 9.8E-168 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 STK_12120 d12f88acd26f2cc42733a7aea32bb3cb 416 Pfam PF03952 Enolase, N-terminal domain 7 131 7.0E-39 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 STK_12120 d12f88acd26f2cc42733a7aea32bb3cb 416 Hamap MF_00318 Enolase [eno]. 5 405 39.807 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 STK_12120 d12f88acd26f2cc42733a7aea32bb3cb 416 SUPERFAMILY SSF54826 6 134 7.95E-40 T 23-10-2018 STK_12120 d12f88acd26f2cc42733a7aea32bb3cb 416 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 7 413 2.5E-143 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 STK_25670 78e9051f0b783ff466a5ca615b560f60 239 SUPERFAMILY SSF52402 7 197 2.06E-55 T 23-10-2018 STK_25670 78e9051f0b783ff466a5ca615b560f60 239 PIRSF PIRSF000857 1 239 7.0E-90 T 23-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 STK_25670 78e9051f0b783ff466a5ca615b560f60 239 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 34 209 1.7E-48 T 23-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 STK_25670 78e9051f0b783ff466a5ca615b560f60 239 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 1 235 35.399 T 23-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 STK_25670 78e9051f0b783ff466a5ca615b560f60 239 Gene3D G3DSA:3.40.50.620 1 239 2.0E-80 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_25670 78e9051f0b783ff466a5ca615b560f60 239 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 39 233 3.9E-94 T 23-10-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 STK_25670 78e9051f0b783ff466a5ca615b560f60 239 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 21 234 2.0E-64 T 23-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 STK_02260 76d5cb53cc58a4d472391f4eb8982c7c 183 SUPERFAMILY SSF51283 1 170 6.02E-48 T 23-10-2018 IPR036157 dUTPase-like superfamily STK_02260 76d5cb53cc58a4d472391f4eb8982c7c 183 Hamap MF_00146 dCTP deaminase [dcd]. 1 170 32.013 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 STK_02260 76d5cb53cc58a4d472391f4eb8982c7c 183 Pfam PF00692 dUTPase 47 166 1.7E-25 T 23-10-2018 IPR029054 dUTPase-like STK_02260 76d5cb53cc58a4d472391f4eb8982c7c 183 Gene3D G3DSA:2.70.40.10 1 175 7.7E-48 T 23-10-2018 IPR036157 dUTPase-like superfamily STK_02260 76d5cb53cc58a4d472391f4eb8982c7c 183 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 2 169 1.4E-60 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 STK_04060 0554890dc21bfe87ed1ac9b7f1d6ba41 139 Hamap MF_01222 Protein archease. 2 139 42.33 T 23-10-2018 IPR022952 Archease, archaea STK_04060 0554890dc21bfe87ed1ac9b7f1d6ba41 139 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 8 128 9.0E-57 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 STK_04060 0554890dc21bfe87ed1ac9b7f1d6ba41 139 Gene3D G3DSA:3.55.10.10 1 139 9.0E-50 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 STK_04060 0554890dc21bfe87ed1ac9b7f1d6ba41 139 Pfam PF01951 Archease protein family (MTH1598/TM1083) 4 139 4.7E-46 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 STK_04060 0554890dc21bfe87ed1ac9b7f1d6ba41 139 SUPERFAMILY SSF69819 2 139 1.83E-48 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 STK_05620 851ab1e7b8ec053980e25aa4cebb876a 278 SMART SM01092 174 275 6.4E-34 T 23-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal STK_05620 851ab1e7b8ec053980e25aa4cebb876a 278 Gene3D G3DSA:3.30.390.50 173 278 1.4E-40 T 23-10-2018 STK_05620 851ab1e7b8ec053980e25aa4cebb876a 278 Gene3D G3DSA:3.30.43.10 1 53 2.1E-23 T 23-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 STK_05620 851ab1e7b8ec053980e25aa4cebb876a 278 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 168 4.1E-48 T 23-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 STK_05620 851ab1e7b8ec053980e25aa4cebb876a 278 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 175 274 4.2E-27 T 23-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal STK_05620 851ab1e7b8ec053980e25aa4cebb876a 278 SUPERFAMILY SSF56176 3 168 1.68E-49 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 STK_05620 851ab1e7b8ec053980e25aa4cebb876a 278 SUPERFAMILY SSF55447 172 277 9.68E-32 T 23-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily STK_05620 851ab1e7b8ec053980e25aa4cebb876a 278 Gene3D G3DSA:3.30.465.10 59 167 5.2E-40 T 23-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 STK_08990 d89b6fddb82079ce0614e9d17fda2482 630 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 332 353 - T 23-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 STK_08990 d89b6fddb82079ce0614e9d17fda2482 630 SMART SM00220 326 630 3.3E-14 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 STK_08990 d89b6fddb82079ce0614e9d17fda2482 630 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 466 478 - T 23-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 STK_08990 d89b6fddb82079ce0614e9d17fda2482 630 SUPERFAMILY SSF56112 315 615 1.05E-39 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily STK_08990 d89b6fddb82079ce0614e9d17fda2482 630 Gene3D G3DSA:1.10.510.10 313 605 5.3E-36 T 23-10-2018 STK_08990 d89b6fddb82079ce0614e9d17fda2482 630 Pfam PF00069 Protein kinase domain 326 584 2.5E-29 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 STK_03460 090eff975e496420bce6e1c61d427891 300 Pfam PF01564 Spermine/spermidine synthase domain 60 238 1.7E-47 T 23-10-2018 STK_03460 090eff975e496420bce6e1c61d427891 300 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 81 94 - T 23-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 STK_03460 090eff975e496420bce6e1c61d427891 300 SUPERFAMILY SSF53335 2 284 1.69E-77 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_03460 090eff975e496420bce6e1c61d427891 300 Gene3D G3DSA:3.40.50.150 56 299 2.7E-79 T 23-10-2018 STK_03460 090eff975e496420bce6e1c61d427891 300 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 5 284 36.344 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 STK_03460 090eff975e496420bce6e1c61d427891 300 Pfam PF17284 Spermidine synthase tetramerisation domain 6 56 1.6E-9 T 23-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 STK_03460 090eff975e496420bce6e1c61d427891 300 Gene3D G3DSA:2.30.140.10 4 54 7.6E-15 T 23-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 STK_17390 01a4adccb901a28e487a05e97a7b38e1 430 SUPERFAMILY SSF56747 32 226 2.4E-8 T 23-10-2018 STK_02380 0731d70cde77bade85fd49308e2785ea 222 SUPERFAMILY SSF51366 12 221 1.71E-32 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 STK_02380 0731d70cde77bade85fd49308e2785ea 222 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 11 216 6.3E-21 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 STK_02380 0731d70cde77bade85fd49308e2785ea 222 Gene3D G3DSA:3.20.20.70 8 222 4.8E-64 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_02380 0731d70cde77bade85fd49308e2785ea 222 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 12 220 4.9E-79 T 23-10-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 STK_02380 0731d70cde77bade85fd49308e2785ea 222 SMART SM00934 12 216 1.4E-37 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 STK_21300 b7d81665075ff35df8ea97b665a20f8a 108 Pfam PF04032 RNAse P Rpr2/Rpp21/SNM1 subunit domain 25 90 9.0E-11 T 23-10-2018 IPR007175 RNAse P, Rpr2/Rpp21 subunit Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 STK_21300 b7d81665075ff35df8ea97b665a20f8a 108 Hamap MF_00757 Ribonuclease P protein component 4 [rnp4]. 2 99 22.622 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 STK_21300 b7d81665075ff35df8ea97b665a20f8a 108 Gene3D G3DSA:2.20.25.200 57 108 9.0E-12 T 23-10-2018 STK_21300 b7d81665075ff35df8ea97b665a20f8a 108 PIRSF PIRSF004878 1 107 5.2E-26 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 STK_08000 0136c47bbae2ea547ad2f79fa549ad7f 130 Gene3D G3DSA:1.20.120.330 3 129 4.3E-21 T 23-10-2018 STK_08000 0136c47bbae2ea547ad2f79fa549ad7f 130 SMART SM00748 10 120 5.9E-34 T 23-10-2018 IPR007842 HEPN domain STK_08000 0136c47bbae2ea547ad2f79fa549ad7f 130 Pfam PF05168 HEPN domain 6 126 1.2E-26 T 23-10-2018 IPR007842 HEPN domain STK_08000 0136c47bbae2ea547ad2f79fa549ad7f 130 SUPERFAMILY SSF81593 9 129 5.1E-24 T 23-10-2018 STK_07700 a9bf1dc30f1a69e5dea48de0cdab75f0 254 SUPERFAMILY SSF54631 194 247 1.57E-13 T 23-10-2018 STK_07700 a9bf1dc30f1a69e5dea48de0cdab75f0 254 Pfam PF00571 CBS domain 132 186 1.6E-12 T 23-10-2018 IPR000644 CBS domain STK_07700 a9bf1dc30f1a69e5dea48de0cdab75f0 254 Pfam PF00571 CBS domain 199 246 1.9E-11 T 23-10-2018 IPR000644 CBS domain STK_07700 a9bf1dc30f1a69e5dea48de0cdab75f0 254 Pfam PF00571 CBS domain 5 58 1.1E-7 T 23-10-2018 IPR000644 CBS domain STK_07700 a9bf1dc30f1a69e5dea48de0cdab75f0 254 Pfam PF00571 CBS domain 70 124 3.4E-13 T 23-10-2018 IPR000644 CBS domain STK_07700 a9bf1dc30f1a69e5dea48de0cdab75f0 254 SUPERFAMILY SSF54631 4 61 4.12E-9 T 23-10-2018 STK_07700 a9bf1dc30f1a69e5dea48de0cdab75f0 254 Gene3D G3DSA:3.10.580.10 63 193 6.1E-35 T 23-10-2018 STK_07700 a9bf1dc30f1a69e5dea48de0cdab75f0 254 Gene3D G3DSA:3.10.580.10 194 253 7.8E-15 T 23-10-2018 STK_07700 a9bf1dc30f1a69e5dea48de0cdab75f0 254 SMART SM00116 77 124 1.1E-10 T 23-10-2018 IPR000644 CBS domain STK_07700 a9bf1dc30f1a69e5dea48de0cdab75f0 254 SMART SM00116 139 186 2.5E-10 T 23-10-2018 IPR000644 CBS domain STK_07700 a9bf1dc30f1a69e5dea48de0cdab75f0 254 SMART SM00116 201 248 4.5E-10 T 23-10-2018 IPR000644 CBS domain STK_07700 a9bf1dc30f1a69e5dea48de0cdab75f0 254 SMART SM00116 12 59 2.3E-6 T 23-10-2018 IPR000644 CBS domain STK_07700 a9bf1dc30f1a69e5dea48de0cdab75f0 254 SUPERFAMILY SSF54631 61 187 7.43E-34 T 23-10-2018 STK_07700 a9bf1dc30f1a69e5dea48de0cdab75f0 254 Gene3D G3DSA:3.10.580.10 1 62 2.2E-9 T 23-10-2018 STK_24160 09ef3a82dd10da31a2f4d3a8a6393ed6 255 SUPERFAMILY SSF52096 3 254 1.72E-92 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily STK_24160 09ef3a82dd10da31a2f4d3a8a6393ed6 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 254 7.0E-81 T 23-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 STK_24160 09ef3a82dd10da31a2f4d3a8a6393ed6 255 Gene3D G3DSA:1.10.12.10 199 255 2.6E-22 T 23-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal STK_24160 09ef3a82dd10da31a2f4d3a8a6393ed6 255 Gene3D G3DSA:3.90.226.10 4 198 1.5E-74 T 23-10-2018 STK_24160 09ef3a82dd10da31a2f4d3a8a6393ed6 255 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 97 117 - T 23-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 STK_13014 2f06a5a473eb5647a2037dcd444a0d43 68 Pfam PF01850 PIN domain 2 57 1.2E-7 T 23-10-2018 IPR002716 PIN domain STK_13014 2f06a5a473eb5647a2037dcd444a0d43 68 SUPERFAMILY SSF88723 2 58 3.92E-13 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_13014 2f06a5a473eb5647a2037dcd444a0d43 68 Gene3D G3DSA:3.40.50.1010 1 67 4.8E-14 T 23-10-2018 STK_20740 cb137b5403330565f4820d39637342b9 364 Gene3D G3DSA:3.40.50.620 4 216 3.2E-66 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_20740 cb137b5403330565f4820d39637342b9 364 Hamap MF_02009 Tyrosine--tRNA ligase [tyrS]. 10 346 46.763 T 23-10-2018 IPR023678 Tyrosine-tRNA ligase, type 4 GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 STK_20740 cb137b5403330565f4820d39637342b9 364 Gene3D G3DSA:1.10.240.10 218 364 1.8E-45 T 23-10-2018 STK_20740 cb137b5403330565f4820d39637342b9 364 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 13 349 2.8E-40 T 23-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 STK_20740 cb137b5403330565f4820d39637342b9 364 PIRSF PIRSF006588 6 364 2.7E-124 T 23-10-2018 IPR023617 Tyrosine-tRNA ligase, archaeal/eukaryotic-type GO:0004831 KEGG: 00970+6.1.1.1 STK_20740 cb137b5403330565f4820d39637342b9 364 SUPERFAMILY SSF52374 6 350 1.41E-72 T 23-10-2018 STK_20740 cb137b5403330565f4820d39637342b9 364 Pfam PF00579 tRNA synthetases class I (W and Y) 35 225 5.7E-34 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_20740 cb137b5403330565f4820d39637342b9 364 Pfam PF00579 tRNA synthetases class I (W and Y) 237 338 3.0E-9 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_20740 cb137b5403330565f4820d39637342b9 364 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 49 71 1.7E-11 T 23-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 STK_20740 cb137b5403330565f4820d39637342b9 364 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 159 174 1.7E-11 T 23-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 STK_20740 cb137b5403330565f4820d39637342b9 364 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 209 221 1.7E-11 T 23-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 STK_20740 cb137b5403330565f4820d39637342b9 364 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 176 198 1.7E-11 T 23-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 STK_24760 0c52ae04c0f5de7a962a0e82ee1998a4 648 PIRSF PIRSF006060 9 514 3.5E-63 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_24760 0c52ae04c0f5de7a962a0e82ee1998a4 648 PIRSF PIRSF006060 510 647 340.0 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_24760 0c52ae04c0f5de7a962a0e82ee1998a4 648 Pfam PF13520 Amino acid permease 27 478 4.4E-43 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_24760 0c52ae04c0f5de7a962a0e82ee1998a4 648 Gene3D G3DSA:1.20.1740.10 19 517 1.4E-55 T 23-10-2018 STK_18390 6d1334201c130a8ab54294e95b389798 270 SUPERFAMILY SSF54862 22 224 9.84E-56 T 23-10-2018 STK_18390 6d1334201c130a8ab54294e95b389798 270 Gene3D G3DSA:3.30.70.20 67 248 8.2E-47 T 23-10-2018 STK_18390 6d1334201c130a8ab54294e95b389798 270 Gene3D G3DSA:3.30.70.20 16 54 2.0E-6 T 23-10-2018 STK_18390 6d1334201c130a8ab54294e95b389798 270 Pfam PF13247 4Fe-4S dicluster domain 86 185 1.0E-19 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_19700 62c6ae645fab42985d7ddbb4614c6495 273 SUPERFAMILY SSF51735 1 265 9.92E-65 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_19700 62c6ae645fab42985d7ddbb4614c6495 273 Gene3D G3DSA:3.40.50.720 4 254 2.4E-103 T 23-10-2018 STK_19700 62c6ae645fab42985d7ddbb4614c6495 273 Pfam PF04321 RmlD substrate binding domain 1 260 2.6E-58 T 23-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 STK_19700 62c6ae645fab42985d7ddbb4614c6495 273 Gene3D G3DSA:3.90.25.10 160 248 2.4E-103 T 23-10-2018 STK_06720 838d5fd91893023fb9c58ca3a45b87f8 195 Gene3D G3DSA:3.40.50.1820 3 191 2.3E-22 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold STK_06720 838d5fd91893023fb9c58ca3a45b87f8 195 SUPERFAMILY SSF53474 4 191 5.17E-22 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold STK_06720 838d5fd91893023fb9c58ca3a45b87f8 195 Pfam PF00326 Prolyl oligopeptidase family 5 171 3.2E-9 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 STK_12905 7cbe6edad079360ac6c93a85f0bbd2ea 90 Pfam PF01918 Alba 7 62 8.5E-15 T 23-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 STK_12905 7cbe6edad079360ac6c93a85f0bbd2ea 90 PIRSF PIRSF028732 3 89 2.0E-27 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 STK_12905 7cbe6edad079360ac6c93a85f0bbd2ea 90 Gene3D G3DSA:3.30.110.20 2 90 2.1E-35 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 STK_12905 7cbe6edad079360ac6c93a85f0bbd2ea 90 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 14 90 1.0E-36 T 23-10-2018 STK_12905 7cbe6edad079360ac6c93a85f0bbd2ea 90 SUPERFAMILY SSF82704 5 88 6.15E-25 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 STK_12905 7cbe6edad079360ac6c93a85f0bbd2ea 90 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 1 88 16.325 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 STK_08670 25ca332507de4cb1883aad19b73e5292 221 SUPERFAMILY SSF102588 1 195 4.58E-46 T 23-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 STK_08670 25ca332507de4cb1883aad19b73e5292 221 Gene3D G3DSA:3.40.50.10320 1 215 1.1E-47 T 23-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 STK_08670 25ca332507de4cb1883aad19b73e5292 221 Pfam PF02585 GlcNAc-PI de-N-acetylase 4 127 3.1E-29 T 23-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 STK_03760 8bdee1be664a7915a6f786d1f33de111 747 Gene3D G3DSA:3.10.330.10 90 161 9.6E-8 T 23-10-2018 STK_03760 8bdee1be664a7915a6f786d1f33de111 747 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 5 744 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 STK_03760 8bdee1be664a7915a6f786d1f33de111 747 Gene3D G3DSA:1.10.8.60 347 443 9.0E-33 T 23-10-2018 STK_03760 8bdee1be664a7915a6f786d1f33de111 747 SMART SM01072 104 167 1.1E-19 T 23-10-2018 IPR004201 CDC48, domain 2 STK_03760 8bdee1be664a7915a6f786d1f33de111 747 Pfam PF09336 Vps4 C terminal oligomerisation domain 710 740 1.6E-4 T 23-10-2018 IPR015415 Vps4 oligomerisation, C-terminal STK_03760 8bdee1be664a7915a6f786d1f33de111 747 ProSitePatterns PS00674 AAA-protein family signature. 592 610 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 STK_03760 8bdee1be664a7915a6f786d1f33de111 747 Gene3D G3DSA:3.40.50.300 449 736 4.5E-104 T 23-10-2018 STK_03760 8bdee1be664a7915a6f786d1f33de111 747 SUPERFAMILY SSF54585 90 181 1.44E-23 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily STK_03760 8bdee1be664a7915a6f786d1f33de111 747 SUPERFAMILY SSF52540 449 742 1.74E-76 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_03760 8bdee1be664a7915a6f786d1f33de111 747 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 7 89 2.7E-24 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain STK_03760 8bdee1be664a7915a6f786d1f33de111 747 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 104 166 1.7E-16 T 23-10-2018 IPR004201 CDC48, domain 2 STK_03760 8bdee1be664a7915a6f786d1f33de111 747 SMART SM01073 6 89 2.0E-31 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain STK_03760 8bdee1be664a7915a6f786d1f33de111 747 Gene3D G3DSA:2.40.40.20 1 89 4.7E-23 T 23-10-2018 STK_03760 8bdee1be664a7915a6f786d1f33de111 747 SUPERFAMILY SSF52540 173 442 6.63E-75 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_03760 8bdee1be664a7915a6f786d1f33de111 747 Gene3D G3DSA:3.40.50.300 172 345 5.3E-73 T 23-10-2018 STK_03760 8bdee1be664a7915a6f786d1f33de111 747 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 491 621 5.6E-47 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_03760 8bdee1be664a7915a6f786d1f33de111 747 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 216 345 3.1E-48 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_03760 8bdee1be664a7915a6f786d1f33de111 747 SMART SM00382 487 624 8.7E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_03760 8bdee1be664a7915a6f786d1f33de111 747 SMART SM00382 212 348 9.1E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_03760 8bdee1be664a7915a6f786d1f33de111 747 ProSitePatterns PS00674 AAA-protein family signature. 316 334 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 STK_03760 8bdee1be664a7915a6f786d1f33de111 747 SUPERFAMILY SSF50692 2 87 8.7E-23 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily STK_03760 8bdee1be664a7915a6f786d1f33de111 747 Gene3D G3DSA:1.10.8.60 623 723 4.5E-104 T 23-10-2018 STK_00630 e14f899c9c967cad4270f3432fb3b525 465 PIRSF PIRSF000331 1 465 7.8E-156 T 23-10-2018 IPR004925 HpaB/PvcC/4-BUDH STK_00630 e14f899c9c967cad4270f3432fb3b525 465 SUPERFAMILY SSF56645 1 261 2.75E-68 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 STK_00630 e14f899c9c967cad4270f3432fb3b525 465 SUPERFAMILY SSF47203 252 463 2.72E-53 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 STK_00630 e14f899c9c967cad4270f3432fb3b525 465 Gene3D G3DSA:2.40.110.10 137 262 1.8E-46 T 23-10-2018 STK_00630 e14f899c9c967cad4270f3432fb3b525 465 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 268 463 5.4E-51 T 23-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal STK_00630 e14f899c9c967cad4270f3432fb3b525 465 Gene3D G3DSA:1.20.140.10 265 464 2.9E-58 T 23-10-2018 STK_00630 e14f899c9c967cad4270f3432fb3b525 465 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 4 261 7.5E-82 T 23-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal STK_00630 e14f899c9c967cad4270f3432fb3b525 465 Gene3D G3DSA:1.10.3140.10 1 135 2.7E-22 T 23-10-2018 STK_00720 809fd10b5bcebeec2682a780a799f520 194 Gene3D G3DSA:1.10.357.10 1 192 1.7E-32 T 23-10-2018 STK_00720 809fd10b5bcebeec2682a780a799f520 194 SUPERFAMILY SSF46689 2 80 8.21E-18 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 STK_00720 809fd10b5bcebeec2682a780a799f520 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.0E-14 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 STK_00720 809fd10b5bcebeec2682a780a799f520 194 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 23-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site STK_00720 809fd10b5bcebeec2682a780a799f520 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 4.3E-8 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 STK_00720 809fd10b5bcebeec2682a780a799f520 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 4.3E-8 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 STK_10760 21dbe3198cf1ccb124b5c946e6554435 113 Pfam PF01022 Bacterial regulatory protein, arsR family 17 63 1.1E-16 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 STK_10760 21dbe3198cf1ccb124b5c946e6554435 113 SMART SM00418 10 89 1.7E-29 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 STK_10760 21dbe3198cf1ccb124b5c946e6554435 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 32 43 1.3E-16 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 STK_10760 21dbe3198cf1ccb124b5c946e6554435 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.3E-16 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 STK_10760 21dbe3198cf1ccb124b5c946e6554435 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 1.3E-16 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 STK_10760 21dbe3198cf1ccb124b5c946e6554435 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 1.3E-16 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 STK_10760 21dbe3198cf1ccb124b5c946e6554435 113 SUPERFAMILY SSF46785 5 90 2.73E-24 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_10760 21dbe3198cf1ccb124b5c946e6554435 113 Gene3D G3DSA:1.10.10.10 2 96 1.3E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_09630 5955cd706b8aba9e184783c87f318dbb 337 SUPERFAMILY SSF56059 2 200 8.93E-45 T 23-10-2018 STK_09630 5955cd706b8aba9e184783c87f318dbb 337 SUPERFAMILY SSF52210 208 326 3.53E-38 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 STK_09630 5955cd706b8aba9e184783c87f318dbb 337 Pfam PF08442 ATP-grasp domain 2 169 7.6E-28 T 23-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 STK_09630 5955cd706b8aba9e184783c87f318dbb 337 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 214 238 - T 23-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 STK_09630 5955cd706b8aba9e184783c87f318dbb 337 PIRSF PIRSF001554 1 336 1.6E-97 T 23-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 STK_09630 5955cd706b8aba9e184783c87f318dbb 337 Gene3D G3DSA:3.30.470.20 1 197 1.1E-49 T 23-10-2018 STK_09630 5955cd706b8aba9e184783c87f318dbb 337 Pfam PF00549 CoA-ligase 221 324 1.5E-14 T 23-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 STK_09630 5955cd706b8aba9e184783c87f318dbb 337 Gene3D G3DSA:3.40.50.261 204 335 1.2E-41 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 STK_09630 5955cd706b8aba9e184783c87f318dbb 337 Gene3D G3DSA:3.30.1490.20 21 81 1.1E-49 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 STK_04310 09efc783b70c5f531118e007cba421c3 1047 Pfam PF08264 Anticodon-binding domain of tRNA 683 831 4.1E-32 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 STK_04310 09efc783b70c5f531118e007cba421c3 1047 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 57 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_04310 09efc783b70c5f531118e007cba421c3 1047 Gene3D G3DSA:3.40.50.620 11 622 2.4E-221 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_04310 09efc783b70c5f531118e007cba421c3 1047 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 4 839 1.3E-278 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 STK_04310 09efc783b70c5f531118e007cba421c3 1047 Gene3D G3DSA:1.10.730.10 639 823 1.1E-44 T 23-10-2018 STK_04310 09efc783b70c5f531118e007cba421c3 1047 SUPERFAMILY SSF47323 646 868 3.92E-53 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_04310 09efc783b70c5f531118e007cba421c3 1047 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 634 8.5E-181 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_04310 09efc783b70c5f531118e007cba421c3 1047 SUPERFAMILY SSF50677 197 393 1.67E-52 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 STK_04310 09efc783b70c5f531118e007cba421c3 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 219 242 3.6E-27 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 STK_04310 09efc783b70c5f531118e007cba421c3 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 553 562 3.6E-27 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 STK_04310 09efc783b70c5f531118e007cba421c3 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 38 49 3.6E-27 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 STK_04310 09efc783b70c5f531118e007cba421c3 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 391 406 3.6E-27 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 STK_04310 09efc783b70c5f531118e007cba421c3 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 515 528 3.6E-27 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 STK_04310 09efc783b70c5f531118e007cba421c3 1047 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 1 1042 12.731 T 23-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 STK_04310 09efc783b70c5f531118e007cba421c3 1047 Gene3D G3DSA:3.90.740.10 195 397 2.4E-221 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 STK_04310 09efc783b70c5f531118e007cba421c3 1047 SUPERFAMILY SSF47323 956 1040 3.86E-8 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_04310 09efc783b70c5f531118e007cba421c3 1047 SUPERFAMILY SSF52374 2 644 2.22E-126 T 23-10-2018 STK_04710 9fa9c80a60bf119fd5005740df5aadf7 418 SUPERFAMILY SSF52540 20 297 1.08E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_04710 9fa9c80a60bf119fd5005740df5aadf7 418 SUPERFAMILY SSF46785 307 413 2.27E-30 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_04710 9fa9c80a60bf119fd5005740df5aadf7 418 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 20 392 1.2E-117 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea STK_04710 9fa9c80a60bf119fd5005740df5aadf7 418 Gene3D G3DSA:1.10.10.10 307 415 2.3E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_04710 9fa9c80a60bf119fd5005740df5aadf7 418 Gene3D G3DSA:1.10.8.60 25 292 7.1E-71 T 23-10-2018 STK_04710 9fa9c80a60bf119fd5005740df5aadf7 418 SMART SM01074 320 403 8.4E-29 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 STK_04710 9fa9c80a60bf119fd5005740df5aadf7 418 Gene3D G3DSA:3.40.50.300 36 217 7.1E-71 T 23-10-2018 STK_04710 9fa9c80a60bf119fd5005740df5aadf7 418 Hamap MF_01407 ORC1-type DNA replication protein. 13 403 26.533 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea STK_04710 9fa9c80a60bf119fd5005740df5aadf7 418 Pfam PF09079 CDC6, C terminal winged helix domain 322 398 4.0E-17 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 STK_04710 9fa9c80a60bf119fd5005740df5aadf7 418 Pfam PF13401 AAA domain 65 177 2.4E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_25620 0132d45c7961936fc19f4c33bbaa5787 213 SUPERFAMILY SSF48008 70 204 6.02E-29 T 23-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal STK_25620 0132d45c7961936fc19f4c33bbaa5787 213 Pfam PF07729 FCD domain 74 195 3.2E-26 T 23-10-2018 IPR011711 GntR, C-terminal STK_25620 0132d45c7961936fc19f4c33bbaa5787 213 SMART SM00345 7 64 9.9E-12 T 23-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 STK_25620 0132d45c7961936fc19f4c33bbaa5787 213 Gene3D G3DSA:1.10.10.10 1 65 7.6E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_25620 0132d45c7961936fc19f4c33bbaa5787 213 SMART SM00895 74 198 2.1E-20 T 23-10-2018 IPR011711 GntR, C-terminal STK_25620 0132d45c7961936fc19f4c33bbaa5787 213 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 56 1.2E-15 T 23-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 STK_25620 0132d45c7961936fc19f4c33bbaa5787 213 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 25 39 2.7E-7 T 23-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 STK_25620 0132d45c7961936fc19f4c33bbaa5787 213 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 55 2.7E-7 T 23-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 STK_25620 0132d45c7961936fc19f4c33bbaa5787 213 Gene3D G3DSA:1.20.120.530 67 206 3.9E-30 T 23-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal STK_25620 0132d45c7961936fc19f4c33bbaa5787 213 SUPERFAMILY SSF46785 2 68 5.17E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_09600 d13ba8b4aa6bf438b29d45c74d876547 337 Gene3D G3DSA:3.40.50.1100 47 335 8.4E-78 T 23-10-2018 STK_09600 d13ba8b4aa6bf438b29d45c74d876547 337 SUPERFAMILY SSF53686 5 335 3.14E-74 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme STK_09600 d13ba8b4aa6bf438b29d45c74d876547 337 Gene3D G3DSA:3.40.50.1100 78 170 8.4E-78 T 23-10-2018 STK_09600 d13ba8b4aa6bf438b29d45c74d876547 337 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 51 331 9.9E-60 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme STK_13350 3dab7be126b3b0a56d1a62119a976df8 339 TIGRFAM TIGR04474 tcm_partner: three-Cys-motif partner protein 52 284 1.2E-17 T 23-10-2018 IPR031009 Three-Cys-motif partner protein STK_11220 6c546c411aa3f9f3b54fafb73c99bdbe 314 Pfam PF02371 Transposase IS116/IS110/IS902 family 193 277 3.6E-27 T 23-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 STK_11220 6c546c411aa3f9f3b54fafb73c99bdbe 314 Pfam PF01548 Transposase 6 132 2.7E-15 T 23-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 STK_04730 21d6d2ebc40c05a93d79ba660f8c355e 440 SUPERFAMILY SSF52540 4 225 3.56E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_04730 21d6d2ebc40c05a93d79ba660f8c355e 440 SMART SM00382 40 161 8.7E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_04730 21d6d2ebc40c05a93d79ba660f8c355e 440 Hamap MF_01508 Replication factor C large subunit [rfcL]. 3 425 33.787 T 23-10-2018 IPR023935 Replication factor C, large subunit STK_04730 21d6d2ebc40c05a93d79ba660f8c355e 440 Gene3D G3DSA:3.40.50.300 4 161 1.7E-39 T 23-10-2018 STK_04730 21d6d2ebc40c05a93d79ba660f8c355e 440 Gene3D G3DSA:1.10.8.60 167 225 9.7E-14 T 23-10-2018 STK_04730 21d6d2ebc40c05a93d79ba660f8c355e 440 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 44 145 5.6E-15 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_11900 fe48ca9f38bfa13216b3655856681536 497 Pfam PF00501 AMP-binding enzyme 31 399 5.1E-74 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 STK_11900 fe48ca9f38bfa13216b3655856681536 497 Gene3D G3DSA:3.40.50.12780 12 395 1.2E-91 T 23-10-2018 STK_11900 fe48ca9f38bfa13216b3655856681536 497 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 23-10-2018 IPR020845 AMP-binding, conserved site STK_11900 fe48ca9f38bfa13216b3655856681536 497 Pfam PF13193 AMP-binding enzyme C-terminal domain 408 486 5.7E-19 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain STK_11900 fe48ca9f38bfa13216b3655856681536 497 SUPERFAMILY SSF56801 27 495 6.28E-128 T 23-10-2018 STK_11900 fe48ca9f38bfa13216b3655856681536 497 Gene3D G3DSA:3.30.300.30 396 497 1.3E-24 T 23-10-2018 STK_03020 1fc2b2bd85217459d3a9641b88c1dd9d 117 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 117 52.802 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 STK_03020 1fc2b2bd85217459d3a9641b88c1dd9d 117 Gene3D G3DSA:3.40.50.620 1 116 4.3E-24 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_03020 1fc2b2bd85217459d3a9641b88c1dd9d 117 SUPERFAMILY SSF52374 16 111 5.16E-16 T 23-10-2018 STK_24020 c4c27348b7cacd1ebb122a4d738dbbe5 459 SMART SM00564 252 284 0.21 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat STK_24020 c4c27348b7cacd1ebb122a4d738dbbe5 459 SMART SM00564 105 149 1.4 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat STK_24020 c4c27348b7cacd1ebb122a4d738dbbe5 459 SMART SM00564 210 242 3.5 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat STK_24020 c4c27348b7cacd1ebb122a4d738dbbe5 459 SMART SM00564 354 385 0.38 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat STK_24020 c4c27348b7cacd1ebb122a4d738dbbe5 459 SMART SM00564 158 202 0.058 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat STK_24020 c4c27348b7cacd1ebb122a4d738dbbe5 459 Gene3D G3DSA:2.130.10.10 179 454 1.8E-36 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 STK_24020 c4c27348b7cacd1ebb122a4d738dbbe5 459 Gene3D G3DSA:2.40.10.480 129 178 9.9E-6 T 23-10-2018 STK_24020 c4c27348b7cacd1ebb122a4d738dbbe5 459 SUPERFAMILY SSF50998 100 419 7.75E-45 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily STK_24020 c4c27348b7cacd1ebb122a4d738dbbe5 459 Pfam PF13360 PQQ-like domain 134 383 2.3E-21 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat STK_02355 974ddaa6acb1448a0e89e4467b77d252 90 Gene3D G3DSA:2.30.30.100 4 89 1.2E-26 T 23-10-2018 STK_02355 974ddaa6acb1448a0e89e4467b77d252 90 Pfam PF01423 LSM domain 16 82 4.8E-21 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type STK_02355 974ddaa6acb1448a0e89e4467b77d252 90 SUPERFAMILY SSF50182 13 84 1.86E-21 T 23-10-2018 IPR010920 LSM domain superfamily STK_02355 974ddaa6acb1448a0e89e4467b77d252 90 SMART SM00651 15 82 6.6E-23 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type STK_19650 0561186785936894fa9da48e9d21b04c 318 Gene3D G3DSA:3.90.550.10 2 215 2.9E-17 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_19650 0561186785936894fa9da48e9d21b04c 318 Pfam PF00535 Glycosyl transferase family 2 5 133 5.1E-14 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 STK_19650 0561186785936894fa9da48e9d21b04c 318 SUPERFAMILY SSF53448 4 215 2.25E-25 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_21170 1f3b1a5515cc7c6442d3e290fd08d49e 584 Gene3D G3DSA:3.40.50.300 1 209 9.0E-13 T 23-10-2018 STK_21170 1f3b1a5515cc7c6442d3e290fd08d49e 584 SUPERFAMILY SSF75712 241 340 2.09E-6 T 23-10-2018 STK_21170 1f3b1a5515cc7c6442d3e290fd08d49e 584 SUPERFAMILY SSF52540 2 568 6.51E-8 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_21170 1f3b1a5515cc7c6442d3e290fd08d49e 584 Gene3D G3DSA:3.40.50.300 374 584 1.9E-13 T 23-10-2018 STK_05190 420d441808bd2f5ff72580c0fb41d767 208 Gene3D G3DSA:3.30.420.10 2 156 1.0E-39 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 STK_05190 420d441808bd2f5ff72580c0fb41d767 208 Hamap MF_00052_A Ribonuclease HII [rnhB]. 2 201 30.852 T 23-10-2018 IPR020787 Ribonuclease HII, archaea GO:0004523|GO:0005737|GO:0006401|GO:0030145 STK_05190 420d441808bd2f5ff72580c0fb41d767 208 SUPERFAMILY SSF53098 1 200 1.67E-55 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily STK_05190 420d441808bd2f5ff72580c0fb41d767 208 Pfam PF01351 Ribonuclease HII 4 194 1.1E-45 T 23-10-2018 IPR024567 Ribonuclease HII/HIII domain STK_05190 420d441808bd2f5ff72580c0fb41d767 208 TIGRFAM TIGR00729 TIGR00729: ribonuclease HII 3 199 1.1E-59 T 23-10-2018 IPR004649 Ribonuclease H2, subunit A GO:0004523|GO:0016070 STK_05190 420d441808bd2f5ff72580c0fb41d767 208 Gene3D G3DSA:1.10.10.460 157 202 1.5E-19 T 23-10-2018 IPR023160 Ribonuclease HII, helix-loop-helix cap domain superfamily GO:0004523 STK_20780 e4d8d2140d0172f875fe3d194dd478d3 341 Hamap MF_01853 Protein pelota homolog [pelA]. 2 340 32.998 T 23-10-2018 IPR023521 Translation release factor pelota, archaea GO:0070481|GO:0070966|GO:0071025 STK_20780 e4d8d2140d0172f875fe3d194dd478d3 341 SUPERFAMILY SSF55315 233 341 5.18E-26 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like STK_20780 e4d8d2140d0172f875fe3d194dd478d3 341 Gene3D G3DSA:3.30.1330.30 240 341 7.9E-33 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like STK_20780 e4d8d2140d0172f875fe3d194dd478d3 341 TIGRFAM TIGR00111 pelota: mRNA surveillance protein pelota 1 340 4.1E-64 T 23-10-2018 IPR004405 Translation release factor pelota GO:0070481|GO:0070966|GO:0071025 STK_20780 e4d8d2140d0172f875fe3d194dd478d3 341 SUPERFAMILY SSF159065 1 121 5.89E-34 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain STK_20780 e4d8d2140d0172f875fe3d194dd478d3 341 SUPERFAMILY SSF53137 127 236 4.8E-9 T 23-10-2018 STK_20780 e4d8d2140d0172f875fe3d194dd478d3 341 Gene3D G3DSA:2.30.30.870 1 124 4.7E-39 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain STK_20780 e4d8d2140d0172f875fe3d194dd478d3 341 Pfam PF03463 eRF1 domain 1 7 120 2.9E-24 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like STK_20780 e4d8d2140d0172f875fe3d194dd478d3 341 SMART SM01194 1 123 7.1E-43 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like STK_20780 e4d8d2140d0172f875fe3d194dd478d3 341 Gene3D G3DSA:3.30.420.60 125 239 8.8E-21 T 23-10-2018 STK_20780 e4d8d2140d0172f875fe3d194dd478d3 341 Pfam PF03465 eRF1 domain 3 242 340 2.1E-23 T 23-10-2018 IPR005142 eRF1 domain 3 STK_20640 8e335d4d0f9ec3ec3f88d972bda9c052 137 Pfam PF00380 Ribosomal protein S9/S16 13 137 3.4E-28 T 23-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 STK_20640 8e335d4d0f9ec3ec3f88d972bda9c052 137 TIGRFAM TIGR03627 uS9_arch: ribosomal protein uS9 7 137 1.7E-55 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_20640 8e335d4d0f9ec3ec3f88d972bda9c052 137 Gene3D G3DSA:3.30.230.10 1 137 3.3E-41 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup STK_20640 8e335d4d0f9ec3ec3f88d972bda9c052 137 ProSitePatterns PS00360 Ribosomal protein S9 signature. 72 90 - T 23-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 STK_20640 8e335d4d0f9ec3ec3f88d972bda9c052 137 Hamap MF_00532_A 30S ribosomal protein S9 [rpsI]. 7 137 33.777 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_20640 8e335d4d0f9ec3ec3f88d972bda9c052 137 SUPERFAMILY SSF54211 7 137 4.17E-33 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold STK_03870 c22e7f997f5b5e8f5918bf7e00347d62 245 SUPERFAMILY SSF55979 127 244 3.3E-25 T 23-10-2018 STK_03870 c22e7f997f5b5e8f5918bf7e00347d62 245 TIGRFAM TIGR00590 pcna: proliferating cell nuclear antigen (pcna) 11 244 4.7E-31 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 STK_03870 c22e7f997f5b5e8f5918bf7e00347d62 245 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 33 51 5.3E-14 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 STK_03870 c22e7f997f5b5e8f5918bf7e00347d62 245 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 55 79 5.3E-14 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 STK_03870 c22e7f997f5b5e8f5918bf7e00347d62 245 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 230 245 5.3E-14 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 STK_03870 c22e7f997f5b5e8f5918bf7e00347d62 245 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 9 28 5.3E-14 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 STK_03870 c22e7f997f5b5e8f5918bf7e00347d62 245 Gene3D G3DSA:3.70.10.10 1 245 5.7E-80 T 23-10-2018 STK_03870 c22e7f997f5b5e8f5918bf7e00347d62 245 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 126 243 3.5E-8 T 23-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 STK_03870 c22e7f997f5b5e8f5918bf7e00347d62 245 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 11 102 6.7E-17 T 23-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 STK_03870 c22e7f997f5b5e8f5918bf7e00347d62 245 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 33 56 - T 23-10-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 STK_03870 c22e7f997f5b5e8f5918bf7e00347d62 245 SUPERFAMILY SSF55979 2 121 1.3E-27 T 23-10-2018 STK_03870 c22e7f997f5b5e8f5918bf7e00347d62 245 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 1 244 29.054 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 STK_02770 37c7fe3b3944d8353f29dc0dbe1f0656 1126 Pfam PF04560 RNA polymerase Rpb2, domain 7 1023 1113 2.3E-29 T 23-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_02770 37c7fe3b3944d8353f29dc0dbe1f0656 1126 Pfam PF04567 RNA polymerase Rpb2, domain 5 602 640 1.2E-10 T 23-10-2018 IPR007647 RNA polymerase Rpb2, domain 5 GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_02770 37c7fe3b3944d8353f29dc0dbe1f0656 1126 Pfam PF00562 RNA polymerase Rpb2, domain 6 650 1021 6.9E-129 T 23-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_02770 37c7fe3b3944d8353f29dc0dbe1f0656 1126 Gene3D G3DSA:3.90.1110.10 174 330 1.6E-60 T 23-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_02770 37c7fe3b3944d8353f29dc0dbe1f0656 1126 TIGRFAM TIGR03670 rpoB_arch: DNA-directed RNA polymerase subunit B 518 1118 0.0 T 23-10-2018 IPR019969 DNA-directed RNA polymerase subunit B (Rpo2) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_02770 37c7fe3b3944d8353f29dc0dbe1f0656 1126 Pfam PF04563 RNA polymerase beta subunit 20 391 4.6E-55 T 23-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_02770 37c7fe3b3944d8353f29dc0dbe1f0656 1126 SUPERFAMILY SSF64484 4 1116 0.0 T 23-10-2018 STK_02770 37c7fe3b3944d8353f29dc0dbe1f0656 1126 Gene3D G3DSA:2.40.270.10 650 1007 8.3E-146 T 23-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_02770 37c7fe3b3944d8353f29dc0dbe1f0656 1126 Gene3D G3DSA:2.40.50.150 680 869 8.3E-146 T 23-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_02770 37c7fe3b3944d8353f29dc0dbe1f0656 1126 Gene3D G3DSA:3.90.1100.10 12 173 1.1E-12 T 23-10-2018 STK_02770 37c7fe3b3944d8353f29dc0dbe1f0656 1126 Gene3D G3DSA:3.90.1100.10 331 513 4.5E-46 T 23-10-2018 STK_02770 37c7fe3b3944d8353f29dc0dbe1f0656 1126 ProSitePatterns PS01166 RNA polymerases beta chain signature. 873 885 - T 23-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_02770 37c7fe3b3944d8353f29dc0dbe1f0656 1126 Gene3D G3DSA:3.90.1800.10 1008 1116 8.5E-42 T 23-10-2018 STK_02770 37c7fe3b3944d8353f29dc0dbe1f0656 1126 Pfam PF04561 RNA polymerase Rpb2, domain 2 167 343 4.7E-42 T 23-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_02770 37c7fe3b3944d8353f29dc0dbe1f0656 1126 Pfam PF04565 RNA polymerase Rpb2, domain 3 411 475 1.1E-24 T 23-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_02770 37c7fe3b3944d8353f29dc0dbe1f0656 1126 Pfam PF04566 RNA polymerase Rpb2, domain 4 518 581 4.5E-23 T 23-10-2018 IPR007646 RNA polymerase Rpb2, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_00940 637b933397c1fab6172123c807d54d15 438 SUPERFAMILY SSF56176 7 169 1.2E-42 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 STK_00940 637b933397c1fab6172123c807d54d15 438 Gene3D G3DSA:3.30.43.10 7 56 2.3E-16 T 23-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 STK_00940 637b933397c1fab6172123c807d54d15 438 Gene3D G3DSA:3.30.465.10 59 169 1.5E-31 T 23-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 STK_00940 637b933397c1fab6172123c807d54d15 438 SUPERFAMILY SSF55447 174 270 1.51E-10 T 23-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily STK_00940 637b933397c1fab6172123c807d54d15 438 Gene3D G3DSA:1.10.150.120 366 437 1.3E-18 T 23-10-2018 STK_00940 637b933397c1fab6172123c807d54d15 438 SUPERFAMILY SSF47741 362 433 2.62E-21 T 23-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily STK_00940 637b933397c1fab6172123c807d54d15 438 Gene3D G3DSA:3.10.20.30 283 365 9.6E-27 T 23-10-2018 IPR012675 Beta-grasp domain superfamily STK_00940 637b933397c1fab6172123c807d54d15 438 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 10 169 1.7E-45 T 23-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 STK_00940 637b933397c1fab6172123c807d54d15 438 SMART SM01092 175 263 1.5E-4 T 23-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal STK_00940 637b933397c1fab6172123c807d54d15 438 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 297 347 9.1E-8 T 23-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 STK_00940 637b933397c1fab6172123c807d54d15 438 Pfam PF01799 [2Fe-2S] binding domain 362 432 4.1E-19 T 23-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 STK_00940 637b933397c1fab6172123c807d54d15 438 SUPERFAMILY SSF54292 281 374 2.75E-20 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 STK_00940 637b933397c1fab6172123c807d54d15 438 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 328 336 - T 23-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 STK_10290 b7ed69b84af574f3b57089aaa51258ea 219 Pfam PF00547 Urease, gamma subunit 1 99 1.3E-38 T 23-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 STK_10290 b7ed69b84af574f3b57089aaa51258ea 219 Gene3D G3DSA:3.30.280.10 1 100 1.0E-40 T 23-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 STK_10290 b7ed69b84af574f3b57089aaa51258ea 219 Gene3D G3DSA:2.10.150.10 107 219 1.1E-44 T 23-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 STK_10290 b7ed69b84af574f3b57089aaa51258ea 219 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 100 3.5E-39 T 23-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 STK_10290 b7ed69b84af574f3b57089aaa51258ea 219 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 8.0E-46 T 23-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 STK_10290 b7ed69b84af574f3b57089aaa51258ea 219 Pfam PF00699 Urease beta subunit 109 200 4.1E-39 T 23-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 STK_10290 b7ed69b84af574f3b57089aaa51258ea 219 Hamap MF_01955 Urease subunit alpha [ureA]. 1 219 44.276 T 23-10-2018 IPR008223 Urease, gamma-beta subunit GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 STK_10290 b7ed69b84af574f3b57089aaa51258ea 219 PIRSF PIRSF001225 1 219 1.8E-97 T 23-10-2018 IPR008223 Urease, gamma-beta subunit GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 STK_10290 b7ed69b84af574f3b57089aaa51258ea 219 SUPERFAMILY SSF51278 115 218 7.72E-42 T 23-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 STK_10290 b7ed69b84af574f3b57089aaa51258ea 219 SUPERFAMILY SSF54111 1 102 1.26E-38 T 23-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 STK_10290 b7ed69b84af574f3b57089aaa51258ea 219 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 109 203 1.3E-37 T 23-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 STK_09490 f5846e421114f256b30633e5219b8517 145 Gene3D G3DSA:3.30.1440.10 1 136 5.1E-48 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_09490 f5846e421114f256b30633e5219b8517 145 Pfam PF01877 RNA binding 3 115 2.6E-20 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 STK_09490 f5846e421114f256b30633e5219b8517 145 Hamap MF_01112 UPF0201 protein . 2 134 27.912 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 STK_09490 f5846e421114f256b30633e5219b8517 145 SUPERFAMILY SSF55282 3 143 8.83E-47 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_07190 854fbdebb311213dcd1b52e10d4d186e 141 Gene3D G3DSA:1.20.1250.20 1 141 1.6E-6 T 23-10-2018 STK_07190 854fbdebb311213dcd1b52e10d4d186e 141 SUPERFAMILY SSF103473 5 137 2.49E-7 T 23-10-2018 IPR036259 MFS transporter superfamily STK_18960 b21d7c494e15589496b8f06c3929e49b 364 SUPERFAMILY SSF55681 1 247 2.91E-53 T 23-10-2018 STK_18960 b21d7c494e15589496b8f06c3929e49b 364 Gene3D G3DSA:3.30.930.10 10 252 1.2E-46 T 23-10-2018 STK_18960 b21d7c494e15589496b8f06c3929e49b 364 Gene3D G3DSA:3.30.390.50 264 354 1.5E-18 T 23-10-2018 STK_15020 de2d11fc53990fad7cdb4bf045b408cc 446 Pfam PF00206 Lyase 14 290 4.9E-42 T 23-10-2018 IPR022761 Fumarate lyase, N-terminal STK_15020 de2d11fc53990fad7cdb4bf045b408cc 446 Gene3D G3DSA:1.10.275.10 34 219 2.0E-99 T 23-10-2018 IPR024083 Fumarase/histidase, N-terminal STK_15020 de2d11fc53990fad7cdb4bf045b408cc 446 PRINTS PR00145 Argininosuccinate lyase family signature 91 113 1.3E-31 T 23-10-2018 STK_15020 de2d11fc53990fad7cdb4bf045b408cc 446 PRINTS PR00145 Argininosuccinate lyase family signature 132 152 1.3E-31 T 23-10-2018 STK_15020 de2d11fc53990fad7cdb4bf045b408cc 446 PRINTS PR00145 Argininosuccinate lyase family signature 300 319 1.3E-31 T 23-10-2018 STK_15020 de2d11fc53990fad7cdb4bf045b408cc 446 PRINTS PR00145 Argininosuccinate lyase family signature 183 199 1.3E-31 T 23-10-2018 STK_15020 de2d11fc53990fad7cdb4bf045b408cc 446 PRINTS PR00145 Argininosuccinate lyase family signature 221 245 1.3E-31 T 23-10-2018 STK_15020 de2d11fc53990fad7cdb4bf045b408cc 446 PRINTS PR00145 Argininosuccinate lyase family signature 265 281 1.3E-31 T 23-10-2018 STK_15020 de2d11fc53990fad7cdb4bf045b408cc 446 Gene3D G3DSA:1.20.200.10 109 345 2.0E-99 T 23-10-2018 STK_15020 de2d11fc53990fad7cdb4bf045b408cc 446 TIGRFAM TIGR00838 argH: argininosuccinate lyase 9 382 6.4E-99 T 23-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 STK_15020 de2d11fc53990fad7cdb4bf045b408cc 446 Hamap MF_00006 Argininosuccinate lyase [argH]. 2 414 32.128 T 23-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 STK_15020 de2d11fc53990fad7cdb4bf045b408cc 446 PRINTS PR00149 Fumarate lyase superfamily signature 92 110 1.7E-15 T 23-10-2018 IPR000362 Fumarate lyase family STK_15020 de2d11fc53990fad7cdb4bf045b408cc 446 PRINTS PR00149 Fumarate lyase superfamily signature 137 155 1.7E-15 T 23-10-2018 IPR000362 Fumarate lyase family STK_15020 de2d11fc53990fad7cdb4bf045b408cc 446 PRINTS PR00149 Fumarate lyase superfamily signature 221 248 1.7E-15 T 23-10-2018 IPR000362 Fumarate lyase family STK_15020 de2d11fc53990fad7cdb4bf045b408cc 446 PRINTS PR00149 Fumarate lyase superfamily signature 265 281 1.7E-15 T 23-10-2018 IPR000362 Fumarate lyase family STK_15020 de2d11fc53990fad7cdb4bf045b408cc 446 Gene3D G3DSA:1.10.40.30 346 377 2.0E-99 T 23-10-2018 STK_15020 de2d11fc53990fad7cdb4bf045b408cc 446 SUPERFAMILY SSF48557 6 418 6.28E-88 T 23-10-2018 IPR008948 L-Aspartase-like GO:0003824 STK_12460 4502a190a1ac8a9bd0a1f1315e0ffccb 206 SUPERFAMILY SSF55261 96 203 1.05E-13 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 STK_12460 4502a190a1ac8a9bd0a1f1315e0ffccb 206 SUPERFAMILY SSF46785 27 89 5.88E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_12460 4502a190a1ac8a9bd0a1f1315e0ffccb 206 Gene3D G3DSA:1.10.10.10 8 100 1.1E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_02010 89ced6980ac70149ad3ea586587aeb53 286 SUPERFAMILY SSF51905 3 161 1.29E-6 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_25660 c67405610720714c15d329f11cbec6a4 628 Gene3D G3DSA:3.90.480.10 347 438 9.6E-15 T 23-10-2018 STK_25660 c67405610720714c15d329f11cbec6a4 628 SUPERFAMILY SSF56014 448 623 1.7E-24 T 23-10-2018 STK_25660 c67405610720714c15d329f11cbec6a4 628 Gene3D G3DSA:3.30.413.10 445 623 8.7E-24 T 23-10-2018 STK_25660 c67405610720714c15d329f11cbec6a4 628 Gene3D G3DSA:3.30.413.10 157 346 5.2E-42 T 23-10-2018 STK_25660 c67405610720714c15d329f11cbec6a4 628 SUPERFAMILY SSF55124 40 157 3.27E-20 T 23-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 STK_25660 c67405610720714c15d329f11cbec6a4 628 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 180 347 1.2E-44 T 23-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 STK_25660 c67405610720714c15d329f11cbec6a4 628 SUPERFAMILY SSF55124 364 432 2.12E-8 T 23-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 STK_25660 c67405610720714c15d329f11cbec6a4 628 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 370 423 7.9E-5 T 23-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 STK_25660 c67405610720714c15d329f11cbec6a4 628 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 79 144 6.9E-9 T 23-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 STK_25660 c67405610720714c15d329f11cbec6a4 628 SUPERFAMILY SSF56014 158 354 2.75E-40 T 23-10-2018 STK_17155 3ce7cdcbd0250addd0022b3cd14bfd45 58 SUPERFAMILY SSF47240 1 44 1.73E-9 T 23-10-2018 IPR009078 Ferritin-like superfamily STK_17155 3ce7cdcbd0250addd0022b3cd14bfd45 58 SMART SM00746 3 40 3.6E-11 T 23-10-2018 IPR011017 TRASH domain STK_17155 3ce7cdcbd0250addd0022b3cd14bfd45 58 Pfam PF04945 YHS domain 1 45 5.4E-20 T 23-10-2018 IPR007029 YHS domain STK_17155 3ce7cdcbd0250addd0022b3cd14bfd45 58 Gene3D G3DSA:1.10.620.20 1 50 7.4E-11 T 23-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 STK_01940 69fa49a6312b7b14b79b2227fe42ff31 261 PIRSF PIRSF000728 1 261 7.3E-65 T 23-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 STK_01940 69fa49a6312b7b14b79b2227fe42ff31 261 Gene3D G3DSA:3.40.1160.10 1 261 7.3E-53 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily STK_01940 69fa49a6312b7b14b79b2227fe42ff31 261 Pfam PF00696 Amino acid kinase family 1 240 2.5E-28 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 STK_01940 69fa49a6312b7b14b79b2227fe42ff31 261 TIGRFAM TIGR00761 argB: acetylglutamate kinase 1 240 2.4E-50 T 23-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 STK_01940 69fa49a6312b7b14b79b2227fe42ff31 261 SUPERFAMILY SSF53633 1 260 1.17E-47 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily STK_01940 69fa49a6312b7b14b79b2227fe42ff31 261 Hamap MF_02082 [LysW]-aminoadipate/[LysW]-glutamate kinase [lysZ]. 1 261 49.382 T 23-10-2018 IPR037529 [LysW]-aminoadipate/[LysW]-glutamate kinase GO:0016301 STK_13410 e6e29607266403b93afa7bce1a2733a8 146 SUPERFAMILY SSF50630 37 128 4.13E-5 T 23-10-2018 IPR021109 Aspartic peptidase domain superfamily STK_02780 219d7612ef0006add1c72a611fb9de3e 426 SUPERFAMILY SSF51735 161 418 6.33E-75 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_02780 219d7612ef0006add1c72a611fb9de3e 426 Gene3D G3DSA:3.40.50.720 159 426 5.6E-90 T 23-10-2018 STK_02780 219d7612ef0006add1c72a611fb9de3e 426 SMART SM01274 16 149 3.9E-72 T 23-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 STK_02780 219d7612ef0006add1c72a611fb9de3e 426 Gene3D G3DSA:3.40.50.10380 1 158 1.2E-68 T 23-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 STK_02780 219d7612ef0006add1c72a611fb9de3e 426 SUPERFAMILY SSF53223 8 159 5.9E-53 T 23-10-2018 STK_02780 219d7612ef0006add1c72a611fb9de3e 426 PIRSF PIRSF000106 36 421 1.2E-81 T 23-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 STK_02780 219d7612ef0006add1c72a611fb9de3e 426 SMART SM00919 161 393 1.0E-117 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 STK_02780 219d7612ef0006add1c72a611fb9de3e 426 Pfam PF00390 Malic enzyme, N-terminal domain 112 149 4.0E-6 T 23-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 STK_02780 219d7612ef0006add1c72a611fb9de3e 426 Pfam PF00390 Malic enzyme, N-terminal domain 17 107 1.6E-17 T 23-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 STK_02780 219d7612ef0006add1c72a611fb9de3e 426 Pfam PF03949 Malic enzyme, NAD binding domain 162 392 5.0E-23 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 STK_14900 2c61c15774d3a575805edf964edf0b2f 212 Pfam PF04055 Radical SAM superfamily 28 180 8.5E-15 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_14900 2c61c15774d3a575805edf964edf0b2f 212 PIRSF PIRSF000370 2 212 4.3E-49 T 23-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 STK_14900 2c61c15774d3a575805edf964edf0b2f 212 SUPERFAMILY SSF102114 27 205 8.37E-19 T 23-10-2018 STK_14900 2c61c15774d3a575805edf964edf0b2f 212 Pfam PF13394 4Fe-4S single cluster domain 26 125 6.3E-15 T 23-10-2018 STK_14900 2c61c15774d3a575805edf964edf0b2f 212 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 4 212 36.457 T 23-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 STK_14900 2c61c15774d3a575805edf964edf0b2f 212 Gene3D G3DSA:3.20.20.70 3 212 3.4E-43 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_04260 b731aa3d6492b078e2a6a7777bb7289e 140 Pfam PF00203 Ribosomal protein S19 40 122 6.8E-33 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04260 b731aa3d6492b078e2a6a7777bb7289e 140 PIRSF PIRSF002144 2 139 4.4E-38 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04260 b731aa3d6492b078e2a6a7777bb7289e 140 SUPERFAMILY SSF54570 39 123 9.29E-27 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04260 b731aa3d6492b078e2a6a7777bb7289e 140 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 38 128 23.459 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04260 b731aa3d6492b078e2a6a7777bb7289e 140 ProSitePatterns PS00323 Ribosomal protein S19 signature. 92 116 - T 23-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04260 b731aa3d6492b078e2a6a7777bb7289e 140 PRINTS PR00975 Ribosomal protein S19 family signature 92 104 4.2E-14 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04260 b731aa3d6492b078e2a6a7777bb7289e 140 PRINTS PR00975 Ribosomal protein S19 family signature 104 119 4.2E-14 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04260 b731aa3d6492b078e2a6a7777bb7289e 140 PRINTS PR00975 Ribosomal protein S19 family signature 72 91 4.2E-14 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04260 b731aa3d6492b078e2a6a7777bb7289e 140 TIGRFAM TIGR01025 uS19_arch: ribosomal protein uS19 10 139 5.1E-59 T 23-10-2018 IPR005713 Ribosomal protein S19A/S15e GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04260 b731aa3d6492b078e2a6a7777bb7289e 140 Gene3D G3DSA:3.30.860.20 7 139 1.4E-51 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04270 353fa3e0ece215238ead6455e586ad5c 238 SMART SM01382 87 220 3.8E-65 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 STK_04270 353fa3e0ece215238ead6455e586ad5c 238 PIRSF PIRSF002158 1 238 5.9E-68 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_04270 353fa3e0ece215238ead6455e586ad5c 238 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 89 215 7.5E-43 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 STK_04270 353fa3e0ece215238ead6455e586ad5c 238 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 11 79 2.1E-14 T 23-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_04270 353fa3e0ece215238ead6455e586ad5c 238 Gene3D G3DSA:4.10.950.10 159 237 2.1E-38 T 23-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04270 353fa3e0ece215238ead6455e586ad5c 238 SUPERFAMILY SSF50249 2 87 1.82E-19 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_04270 353fa3e0ece215238ead6455e586ad5c 238 SUPERFAMILY SSF50104 90 234 3.61E-50 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily STK_04270 353fa3e0ece215238ead6455e586ad5c 238 Hamap MF_01320_A 50S ribosomal protein L2 [rplB]. 1 235 39.379 T 23-10-2018 IPR023672 Ribosomal protein L2, archaeal-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04270 353fa3e0ece215238ead6455e586ad5c 238 Gene3D G3DSA:2.40.50.140 1 77 1.9E-21 T 23-10-2018 STK_04270 353fa3e0ece215238ead6455e586ad5c 238 Gene3D G3DSA:2.30.30.30 81 158 2.6E-25 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 STK_04270 353fa3e0ece215238ead6455e586ad5c 238 SMART SM01383 11 81 2.0E-22 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_12835 8055dedec3ba55d570831234b7ba5a3c 97 SUPERFAMILY SSF141000 5 92 3.27E-21 T 23-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 STK_12835 8055dedec3ba55d570831234b7ba5a3c 97 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 5 95 4.7E-30 T 23-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 STK_12835 8055dedec3ba55d570831234b7ba5a3c 97 Gene3D G3DSA:1.10.20.60 1 93 1.6E-21 T 23-10-2018 STK_12835 8055dedec3ba55d570831234b7ba5a3c 97 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 96 21.616 T 23-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 STK_12835 8055dedec3ba55d570831234b7ba5a3c 97 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 21 90 2.2E-19 T 23-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 STK_02810 d53d3a64a8a52a2b0037fed2ed993951 216 Pfam PF14681 Uracil phosphoribosyltransferase 5 216 5.4E-54 T 23-10-2018 STK_02810 d53d3a64a8a52a2b0037fed2ed993951 216 Hamap MF_01218_A Uracil phosphoribosyltransferase [upp]. 1 216 40.035 T 23-10-2018 IPR034331 Uracil phosphoribosyltransferase, archaea GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 STK_02810 d53d3a64a8a52a2b0037fed2ed993951 216 SUPERFAMILY SSF53271 4 216 2.75E-60 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like STK_02810 d53d3a64a8a52a2b0037fed2ed993951 216 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 5 216 8.2E-65 T 23-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 STK_02810 d53d3a64a8a52a2b0037fed2ed993951 216 Gene3D G3DSA:3.40.50.2020 2 216 1.1E-64 T 23-10-2018 STK_26345 3cb6f565b3a8100964a5e0afe9322f75 91 Gene3D G3DSA:3.30.70.240 1 67 1.7E-25 T 23-10-2018 STK_26345 3cb6f565b3a8100964a5e0afe9322f75 91 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 86 2.1E-16 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 STK_26345 3cb6f565b3a8100964a5e0afe9322f75 91 SUPERFAMILY SSF143430 1 79 2.09E-19 T 23-10-2018 STK_26345 3cb6f565b3a8100964a5e0afe9322f75 91 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 84 16.659 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 STK_26345 3cb6f565b3a8100964a5e0afe9322f75 91 Pfam PF09827 CRISPR associated protein Cas2 1 74 2.5E-17 T 23-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 STK_08940 e4d12c40b63d2817aa8119167905d715 598 Pfam PF05317 Thermopsin 117 355 6.0E-60 T 23-10-2018 IPR007981 Peptidase A5, thermopsin STK_15620 bd9945bec62cb4093a0929dc5f0c76a5 104 SUPERFAMILY SSF46785 10 94 5.94E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_15620 bd9945bec62cb4093a0929dc5f0c76a5 104 Gene3D G3DSA:1.10.10.10 7 101 1.4E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_15620 bd9945bec62cb4093a0929dc5f0c76a5 104 Pfam PF14947 Winged helix-turn-helix 9 80 1.1E-20 T 23-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain STK_03810 2c8ec89c680403dbe428e239aaa506cc 418 Gene3D G3DSA:2.40.30.10 208 323 3.0E-42 T 23-10-2018 STK_03810 2c8ec89c680403dbe428e239aaa506cc 418 TIGRFAM TIGR03680 eif2g_arch: translation initiation factor 2, gamma subunit 6 417 1.8E-202 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit STK_03810 2c8ec89c680403dbe428e239aaa506cc 418 Hamap MF_00119 Translation initiation factor 2 subunit gamma [eif2g]. 2 417 57.039 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit STK_03810 2c8ec89c680403dbe428e239aaa506cc 418 PRINTS PR00315 GTP-binding elongation factor signature 106 117 8.6E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_03810 2c8ec89c680403dbe428e239aaa506cc 418 PRINTS PR00315 GTP-binding elongation factor signature 90 100 8.6E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_03810 2c8ec89c680403dbe428e239aaa506cc 418 PRINTS PR00315 GTP-binding elongation factor signature 11 24 8.6E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_03810 2c8ec89c680403dbe428e239aaa506cc 418 PRINTS PR00315 GTP-binding elongation factor signature 144 153 8.6E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_03810 2c8ec89c680403dbe428e239aaa506cc 418 Gene3D G3DSA:3.40.50.300 2 207 1.6E-64 T 23-10-2018 STK_03810 2c8ec89c680403dbe428e239aaa506cc 418 SUPERFAMILY SSF50465 329 417 6.23E-27 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal STK_03810 2c8ec89c680403dbe428e239aaa506cc 418 Pfam PF03144 Elongation factor Tu domain 2 235 303 3.0E-7 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 STK_03810 2c8ec89c680403dbe428e239aaa506cc 418 SUPERFAMILY SSF50447 207 318 1.1E-34 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily STK_03810 2c8ec89c680403dbe428e239aaa506cc 418 SUPERFAMILY SSF52540 5 205 5.5E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_03810 2c8ec89c680403dbe428e239aaa506cc 418 Gene3D G3DSA:2.40.30.10 325 418 2.7E-27 T 23-10-2018 STK_03810 2c8ec89c680403dbe428e239aaa506cc 418 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 198 3.0E-14 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 STK_03810 2c8ec89c680403dbe428e239aaa506cc 418 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.8E-30 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_03810 2c8ec89c680403dbe428e239aaa506cc 418 Pfam PF09173 Initiation factor eIF2 gamma, C terminal 331 416 1.3E-27 T 23-10-2018 IPR015256 Translation initiation factor 2, gamma subunit, C-terminal STK_21900 3e65372fcd5a5fa036fa6a1ca98b8a8c 236 PIRSF PIRSF037724 1 232 1.9E-76 T 23-10-2018 IPR017271 Transcription regulator HTH, MJ1545, predicted STK_21900 3e65372fcd5a5fa036fa6a1ca98b8a8c 236 Pfam PF01381 Helix-turn-helix 26 73 1.9E-12 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 STK_21900 3e65372fcd5a5fa036fa6a1ca98b8a8c 236 SUPERFAMILY SSF47413 22 73 5.63E-13 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 STK_21900 3e65372fcd5a5fa036fa6a1ca98b8a8c 236 Gene3D G3DSA:1.10.260.40 18 80 1.2E-11 T 23-10-2018 STK_21900 3e65372fcd5a5fa036fa6a1ca98b8a8c 236 SMART SM00530 25 79 2.5E-13 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 STK_03850 91219d2293f63641c6fb75c2daf318fe 338 SUPERFAMILY SSF51726 9 324 2.49E-85 T 23-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 STK_03850 91219d2293f63641c6fb75c2daf318fe 338 Hamap MF_00288 Methionine synthase [metE]. 7 318 45.697 T 23-10-2018 IPR022921 Methionine synthase MetE, archaeal GO:0008168|GO:0009086 STK_03850 91219d2293f63641c6fb75c2daf318fe 338 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 7 315 1.0E-63 T 23-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 STK_03850 91219d2293f63641c6fb75c2daf318fe 338 Gene3D G3DSA:3.20.20.210 2 331 7.7E-118 T 23-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 STK_02280 22f27c4282e2bed82d6719116caa8130 233 Pfam PF13192 Thioredoxin domain 151 228 3.0E-15 T 23-10-2018 IPR012336 Thioredoxin-like fold STK_02280 22f27c4282e2bed82d6719116caa8130 233 Pfam PF13192 Thioredoxin domain 38 118 2.1E-9 T 23-10-2018 IPR012336 Thioredoxin-like fold STK_02280 22f27c4282e2bed82d6719116caa8130 233 Gene3D G3DSA:3.40.30.10 131 228 2.3E-25 T 23-10-2018 STK_02280 22f27c4282e2bed82d6719116caa8130 233 SUPERFAMILY SSF52833 132 225 5.82E-15 T 23-10-2018 IPR036249 Thioredoxin-like superfamily STK_02280 22f27c4282e2bed82d6719116caa8130 233 SUPERFAMILY SSF52833 9 125 8.07E-14 T 23-10-2018 IPR036249 Thioredoxin-like superfamily STK_02280 22f27c4282e2bed82d6719116caa8130 233 Gene3D G3DSA:3.40.30.10 7 124 1.5E-24 T 23-10-2018 STK_02280 22f27c4282e2bed82d6719116caa8130 233 TIGRFAM TIGR02187 GlrX_arch: glutaredoxin-like domain protein 10 229 1.4E-75 T 23-10-2018 IPR011903 Glutaredoxin-like domain STK_18950 b6220267dd5f89ae72f260fbafdac7c6 148 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 10 139 37.584 T 23-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 STK_18950 b6220267dd5f89ae72f260fbafdac7c6 148 SUPERFAMILY SSF51230 19 134 7.98E-34 T 23-10-2018 IPR011053 Single hybrid motif STK_18950 b6220267dd5f89ae72f260fbafdac7c6 148 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 57 86 - T 23-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 STK_18950 b6220267dd5f89ae72f260fbafdac7c6 148 Gene3D G3DSA:2.40.50.100 1 129 4.5E-37 T 23-10-2018 STK_18950 b6220267dd5f89ae72f260fbafdac7c6 148 Pfam PF01597 Glycine cleavage H-protein 16 134 1.9E-41 T 23-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate STK_02290 17666ac3bb8a4e216a5553c2582962ca 230 Gene3D G3DSA:3.30.700.20 11 210 7.9E-103 T 23-10-2018 IPR027485 AMMECR1, N-terminal STK_02290 17666ac3bb8a4e216a5553c2582962ca 230 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 19 202 3.8E-55 T 23-10-2018 IPR027623 AmmeMemoRadiSam system protein A STK_02290 17666ac3bb8a4e216a5553c2582962ca 230 SUPERFAMILY SSF143447 7 214 1.83E-67 T 23-10-2018 IPR036071 AMMECR1 domain superfamily STK_02290 17666ac3bb8a4e216a5553c2582962ca 230 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 12 212 4.8E-56 T 23-10-2018 IPR023473 AMMECR1 STK_02290 17666ac3bb8a4e216a5553c2582962ca 230 Pfam PF01871 AMMECR1 22 201 1.3E-47 T 23-10-2018 IPR002733 AMMECR1 domain STK_02290 17666ac3bb8a4e216a5553c2582962ca 230 Gene3D G3DSA:3.30.1490.150 123 198 7.9E-103 T 23-10-2018 STK_02290 17666ac3bb8a4e216a5553c2582962ca 230 Hamap MF_00645 Protein . 13 200 35.726 T 23-10-2018 IPR023472 Uncharacterised protein family MJ0810 STK_08890 4823a7a9cd60d69dae6806f072ca7bce 432 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 289 301 - T 23-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal STK_08890 4823a7a9cd60d69dae6806f072ca7bce 432 Gene3D G3DSA:1.10.579.10 258 432 3.0E-80 T 23-10-2018 STK_08890 4823a7a9cd60d69dae6806f072ca7bce 432 Gene3D G3DSA:3.40.50.620 1 126 1.0E-37 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_08890 4823a7a9cd60d69dae6806f072ca7bce 432 Gene3D G3DSA:1.25.40.80 164 257 2.0E-24 T 23-10-2018 STK_08890 4823a7a9cd60d69dae6806f072ca7bce 432 PRINTS PR00147 DNA photolyase signature 289 305 2.4E-17 T 23-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 STK_08890 4823a7a9cd60d69dae6806f072ca7bce 432 PRINTS PR00147 DNA photolyase signature 309 327 2.4E-17 T 23-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 STK_08890 4823a7a9cd60d69dae6806f072ca7bce 432 PRINTS PR00147 DNA photolyase signature 348 362 2.4E-17 T 23-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 STK_08890 4823a7a9cd60d69dae6806f072ca7bce 432 Pfam PF03441 FAD binding domain of DNA photolyase 240 426 2.6E-68 T 23-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 STK_08890 4823a7a9cd60d69dae6806f072ca7bce 432 Pfam PF00875 DNA photolyase 4 149 2.3E-31 T 23-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 STK_08890 4823a7a9cd60d69dae6806f072ca7bce 432 SUPERFAMILY SSF48173 175 429 3.01E-85 T 23-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 STK_08890 4823a7a9cd60d69dae6806f072ca7bce 432 SUPERFAMILY SSF52425 4 155 1.05E-38 T 23-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 STK_02230 14eaf19fc08da2ef60eb64b979083de4 600 Pfam PF04679 ATP dependent DNA ligase C terminal region 460 569 2.1E-27 T 23-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 STK_02230 14eaf19fc08da2ef60eb64b979083de4 600 Gene3D G3DSA:3.30.470.30 232 437 4.8E-76 T 23-10-2018 STK_02230 14eaf19fc08da2ef60eb64b979083de4 600 Gene3D G3DSA:1.10.3260.10 1 231 6.2E-77 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 STK_02230 14eaf19fc08da2ef60eb64b979083de4 600 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 258 266 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 STK_02230 14eaf19fc08da2ef60eb64b979083de4 600 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 58 585 5.1E-178 T 23-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 STK_02230 14eaf19fc08da2ef60eb64b979083de4 600 Pfam PF04675 DNA ligase N terminus 2 183 2.1E-38 T 23-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 STK_02230 14eaf19fc08da2ef60eb64b979083de4 600 SUPERFAMILY SSF117018 2 238 1.44E-65 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 STK_02230 14eaf19fc08da2ef60eb64b979083de4 600 Gene3D G3DSA:2.40.50.140 438 600 5.8E-64 T 23-10-2018 STK_02230 14eaf19fc08da2ef60eb64b979083de4 600 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 409 435 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 STK_02230 14eaf19fc08da2ef60eb64b979083de4 600 SUPERFAMILY SSF56091 229 435 3.12E-50 T 23-10-2018 STK_02230 14eaf19fc08da2ef60eb64b979083de4 600 Pfam PF01068 ATP dependent DNA ligase domain 235 435 1.7E-61 T 23-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 STK_02230 14eaf19fc08da2ef60eb64b979083de4 600 Hamap MF_00407 DNA ligase [lig]. 1 585 31.295 T 23-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 STK_02230 14eaf19fc08da2ef60eb64b979083de4 600 SUPERFAMILY SSF50249 444 585 2.14E-47 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_12240 9e24c3ed3c6833893545b42a8a5051e0 809 Gene3D G3DSA:1.10.730.10 15 754 2.0E-217 T 23-10-2018 STK_12240 9e24c3ed3c6833893545b42a8a5051e0 809 Hamap MF_02005 Valine--tRNA ligase [valS]. 14 797 26.136 T 23-10-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 STK_12240 9e24c3ed3c6833893545b42a8a5051e0 809 PRINTS PR00986 Valyl-tRNA synthetase signature 242 259 1.6E-13 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 STK_12240 9e24c3ed3c6833893545b42a8a5051e0 809 PRINTS PR00986 Valyl-tRNA synthetase signature 53 64 1.6E-13 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 STK_12240 9e24c3ed3c6833893545b42a8a5051e0 809 PRINTS PR00986 Valyl-tRNA synthetase signature 467 488 1.6E-13 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 STK_12240 9e24c3ed3c6833893545b42a8a5051e0 809 PRINTS PR00986 Valyl-tRNA synthetase signature 498 516 1.6E-13 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 STK_12240 9e24c3ed3c6833893545b42a8a5051e0 809 TIGRFAM TIGR00422 valS: valine--tRNA ligase 15 802 6.8E-219 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 STK_12240 9e24c3ed3c6833893545b42a8a5051e0 809 SUPERFAMILY SSF47323 598 803 3.74E-45 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_12240 9e24c3ed3c6833893545b42a8a5051e0 809 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 60 71 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_12240 9e24c3ed3c6833893545b42a8a5051e0 809 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 582 3.4E-127 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_12240 9e24c3ed3c6833893545b42a8a5051e0 809 Gene3D G3DSA:3.90.740.10 188 354 2.0E-217 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 STK_12240 9e24c3ed3c6833893545b42a8a5051e0 809 Pfam PF08264 Anticodon-binding domain of tRNA 625 760 1.7E-30 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 STK_12240 9e24c3ed3c6833893545b42a8a5051e0 809 Gene3D G3DSA:3.40.50.620 34 547 2.0E-217 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_12240 9e24c3ed3c6833893545b42a8a5051e0 809 SUPERFAMILY SSF50677 205 352 1.7E-50 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 STK_12240 9e24c3ed3c6833893545b42a8a5051e0 809 SUPERFAMILY SSF52374 7 591 2.56E-117 T 23-10-2018 STK_12165 298265fbd5a362e21bca377bdd41a8ef 86 SUPERFAMILY SSF63562 4 83 5.62E-26 T 23-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 STK_12165 298265fbd5a362e21bca377bdd41a8ef 86 PIRSF PIRSF000778 2 86 2.8E-31 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 STK_12165 298265fbd5a362e21bca377bdd41a8ef 86 Hamap MF_00192 DNA-directed RNA polymerase subunit K [rpoK]. 13 70 20.344 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 STK_12165 298265fbd5a362e21bca377bdd41a8ef 86 ProSitePatterns PS01111 RNA polymerases K / 14 to 18 Kd subunits signature. 16 30 - T 23-10-2018 IPR020708 DNA-directed RNA polymerase, 14-18kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 STK_12165 298265fbd5a362e21bca377bdd41a8ef 86 Gene3D G3DSA:3.90.940.10 1 83 4.7E-31 T 23-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 STK_12165 298265fbd5a362e21bca377bdd41a8ef 86 SMART SM01409 9 64 3.8E-7 T 23-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 STK_12165 298265fbd5a362e21bca377bdd41a8ef 86 Pfam PF01192 RNA polymerase Rpb6 12 64 7.2E-13 T 23-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 STK_02730 9c6758d155b2efeac0294d9dd83242f3 143 Hamap MF_00945_A Transcription termination/antitermination protein NusA [nusA]. 2 143 32.9 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal STK_02730 9c6758d155b2efeac0294d9dd83242f3 143 TIGRFAM TIGR01952 nusA_arch: NusA family KH domain protein, archaeal 3 142 4.7E-58 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal STK_02730 9c6758d155b2efeac0294d9dd83242f3 143 SUPERFAMILY SSF54814 14 75 7.19E-13 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 STK_02730 9c6758d155b2efeac0294d9dd83242f3 143 SUPERFAMILY SSF54814 76 139 1.24E-10 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 STK_02730 9c6758d155b2efeac0294d9dd83242f3 143 Pfam PF13184 NusA-like KH domain 34 95 1.1E-14 T 23-10-2018 IPR025249 KH domain, NusA-like GO:0003723 STK_02730 9c6758d155b2efeac0294d9dd83242f3 143 Gene3D G3DSA:3.30.300.20 75 143 3.5E-27 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta STK_02730 9c6758d155b2efeac0294d9dd83242f3 143 SMART SM00322 33 125 6.2E-5 T 23-10-2018 IPR004087 K Homology domain GO:0003676 STK_02730 9c6758d155b2efeac0294d9dd83242f3 143 Gene3D G3DSA:3.30.300.20 2 74 8.5E-32 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta STK_06390 88131ac3d108c104df2cf7304fd3149c 583 Gene3D G3DSA:3.30.2070.10 380 461 7.1E-74 T 23-10-2018 STK_06390 88131ac3d108c104df2cf7304fd3149c 583 SUPERFAMILY SSF53706 17 506 1.57E-76 T 23-10-2018 STK_06390 88131ac3d108c104df2cf7304fd3149c 583 Pfam PF00384 Molybdopterin oxidoreductase 56 389 2.8E-9 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_06390 88131ac3d108c104df2cf7304fd3149c 583 Gene3D G3DSA:3.40.50.740 54 424 7.1E-74 T 23-10-2018 STK_06390 88131ac3d108c104df2cf7304fd3149c 583 Gene3D G3DSA:3.40.228.10 110 465 7.1E-74 T 23-10-2018 STK_05030 b5d50dcc204e9f7d6e1fc5b0835be91c 145 Gene3D G3DSA:2.40.50.140 3 120 8.4E-33 T 23-10-2018 STK_05030 b5d50dcc204e9f7d6e1fc5b0835be91c 145 Pfam PF01336 OB-fold nucleic acid binding domain 29 88 1.1E-6 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 STK_05030 b5d50dcc204e9f7d6e1fc5b0835be91c 145 SUPERFAMILY SSF50249 5 108 5.52E-30 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_13200 ee4012ce528fa85a782337e305d0e463 316 Gene3D G3DSA:3.40.50.300 1 247 1.3E-38 T 23-10-2018 STK_13200 ee4012ce528fa85a782337e305d0e463 316 Pfam PF13614 AAA domain 4 183 1.0E-27 T 23-10-2018 IPR025669 AAA domain STK_13200 ee4012ce528fa85a782337e305d0e463 316 SUPERFAMILY SSF52540 3 212 1.87E-28 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_08630 5d79910860dcb56cf13bd391c518a222 441 SUPERFAMILY SSF52540 6 231 9.27E-18 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_08630 5d79910860dcb56cf13bd391c518a222 441 Pfam PF13173 AAA domain 46 177 9.3E-23 T 23-10-2018 STK_08630 5d79910860dcb56cf13bd391c518a222 441 Pfam PF13635 Domain of unknown function (DUF4143) 311 392 6.3E-10 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 STK_24090 2861e9b15aed4dc9bc12c9cfa929689e 375 Gene3D G3DSA:1.20.1250.20 190 370 3.4E-12 T 23-10-2018 STK_24090 2861e9b15aed4dc9bc12c9cfa929689e 375 Gene3D G3DSA:1.20.1250.20 2 181 6.7E-15 T 23-10-2018 STK_24090 2861e9b15aed4dc9bc12c9cfa929689e 375 SUPERFAMILY SSF103473 7 371 1.57E-39 T 23-10-2018 IPR036259 MFS transporter superfamily STK_24090 2861e9b15aed4dc9bc12c9cfa929689e 375 Pfam PF07690 Major Facilitator Superfamily 259 365 4.9E-9 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_24090 2861e9b15aed4dc9bc12c9cfa929689e 375 Pfam PF07690 Major Facilitator Superfamily 7 253 1.1E-13 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_19460 350118e0d696c6dea2025cc02f55ef29 465 SMART SM00950 124 447 8.3E-32 T 23-10-2018 IPR003165 Piwi domain GO:0003676 STK_19460 350118e0d696c6dea2025cc02f55ef29 465 Pfam PF02171 Piwi domain 150 330 4.4E-8 T 23-10-2018 IPR003165 Piwi domain GO:0003676 STK_19460 350118e0d696c6dea2025cc02f55ef29 465 Gene3D G3DSA:3.40.50.2300 45 203 3.1E-5 T 23-10-2018 STK_19460 350118e0d696c6dea2025cc02f55ef29 465 SUPERFAMILY SSF53098 17 465 7.78E-45 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily STK_19460 350118e0d696c6dea2025cc02f55ef29 465 Gene3D G3DSA:3.30.420.10 212 465 1.9E-34 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 STK_15230 b4d30cfd4d6d90d2fd5c2884c0a1f069 414 Gene3D G3DSA:3.30.2290.10 37 186 1.0E-11 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal STK_15230 b4d30cfd4d6d90d2fd5c2884c0a1f069 414 SUPERFAMILY SSF111283 28 413 1.57E-56 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 STK_15230 b4d30cfd4d6d90d2fd5c2884c0a1f069 414 Pfam PF01523 Putative modulator of DNA gyrase 28 292 5.6E-33 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 STK_21660 fb1fac9f1abae00539627ed8f0eca84f 409 SUPERFAMILY SSF53659 4 406 8.06E-135 T 23-10-2018 STK_21660 fb1fac9f1abae00539627ed8f0eca84f 409 SMART SM01329 26 402 6.9E-170 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 STK_21660 fb1fac9f1abae00539627ed8f0eca84f 409 Gene3D G3DSA:3.40.718.10 1 409 4.6E-178 T 23-10-2018 STK_21660 fb1fac9f1abae00539627ed8f0eca84f 409 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 27 401 4.1E-107 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 STK_10150 a9c67806e12b613844e28097c6c50233 308 Gene3D G3DSA:3.60.21.10 2 291 2.8E-26 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like STK_10150 a9c67806e12b613844e28097c6c50233 308 SUPERFAMILY SSF56300 5 286 6.03E-71 T 23-10-2018 STK_10150 a9c67806e12b613844e28097c6c50233 308 Pfam PF00149 Calcineurin-like phosphoesterase 6 252 7.8E-9 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 STK_00560 1b38bd73e20dbace3a2a961b7c377cdf 532 Pfam PF04055 Radical SAM superfamily 202 366 2.4E-16 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_00560 1b38bd73e20dbace3a2a961b7c377cdf 532 Gene3D G3DSA:3.80.30.20 194 409 9.1E-29 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe STK_00560 1b38bd73e20dbace3a2a961b7c377cdf 532 SUPERFAMILY SSF52242 53 128 1.24E-8 T 23-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 STK_00560 1b38bd73e20dbace3a2a961b7c377cdf 532 SMART SM00729 197 410 1.5E-42 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 STK_00560 1b38bd73e20dbace3a2a961b7c377cdf 532 Pfam PF02310 B12 binding domain 26 134 7.5E-20 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 STK_00560 1b38bd73e20dbace3a2a961b7c377cdf 532 SUPERFAMILY SSF102114 162 398 3.01E-36 T 23-10-2018 STK_00560 1b38bd73e20dbace3a2a961b7c377cdf 532 Gene3D G3DSA:3.40.50.280 32 149 7.9E-15 T 23-10-2018 STK_17300 4d8d6f065c47c049c64a3a8460093942 268 SMART SM00382 24 198 2.1E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_17300 4d8d6f065c47c049c64a3a8460093942 268 Pfam PF00005 ABC transporter 24 152 1.4E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_17300 4d8d6f065c47c049c64a3a8460093942 268 SUPERFAMILY SSF52540 2 205 2.42E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_17300 4d8d6f065c47c049c64a3a8460093942 268 Gene3D G3DSA:3.40.50.300 1 219 1.6E-43 T 23-10-2018 STK_09730 eaa44b720b5dcb67845b1b323658bf46 589 SUPERFAMILY SSF48208 183 581 2.79E-93 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 STK_09730 eaa44b720b5dcb67845b1b323658bf46 589 Gene3D G3DSA:1.50.10.10 211 589 5.8E-80 T 23-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 STK_09730 eaa44b720b5dcb67845b1b323658bf46 589 Pfam PF00723 Glycosyl hydrolases family 15 211 523 1.5E-47 T 23-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 STK_00750 dbfdabe89e24c99aa8513f7926704bb4 311 SMART SM00829 8 308 0.0012 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 STK_00750 dbfdabe89e24c99aa8513f7926704bb4 311 Gene3D G3DSA:3.90.180.10 1 310 3.3E-70 T 23-10-2018 STK_00750 dbfdabe89e24c99aa8513f7926704bb4 311 SUPERFAMILY SSF51735 125 280 5.36E-27 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_00750 dbfdabe89e24c99aa8513f7926704bb4 311 Pfam PF00107 Zinc-binding dehydrogenase 168 273 2.1E-14 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 STK_00750 dbfdabe89e24c99aa8513f7926704bb4 311 SUPERFAMILY SSF50129 1 157 6.02E-36 T 23-10-2018 IPR011032 GroES-like superfamily STK_00750 dbfdabe89e24c99aa8513f7926704bb4 311 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 120 6.2E-22 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 STK_21770 a57d443ad0fa02c21a9c19dc4f57b875 246 SUPERFAMILY SSF56281 32 238 3.11E-30 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_21770 a57d443ad0fa02c21a9c19dc4f57b875 246 Gene3D G3DSA:3.60.15.10 3 239 1.3E-39 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_21770 a57d443ad0fa02c21a9c19dc4f57b875 246 Pfam PF00753 Metallo-beta-lactamase superfamily 33 218 7.7E-15 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_21770 a57d443ad0fa02c21a9c19dc4f57b875 246 SMART SM00849 32 218 1.0E-14 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_16280 76e3c9ba7ab17fb4ad1eaa8367fa99ff 138 Gene3D G3DSA:3.40.50.1010 1 129 3.4E-28 T 23-10-2018 STK_16280 76e3c9ba7ab17fb4ad1eaa8367fa99ff 138 Pfam PF01850 PIN domain 3 121 4.0E-24 T 23-10-2018 IPR002716 PIN domain STK_16280 76e3c9ba7ab17fb4ad1eaa8367fa99ff 138 SUPERFAMILY SSF88723 1 126 4.21E-18 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_24180 4abbb40e3438910efbae5590b6818aae 387 SUPERFAMILY SSF53901 232 384 4.16E-27 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_24180 4abbb40e3438910efbae5590b6818aae 387 Gene3D G3DSA:3.40.47.10 2 386 2.8E-114 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_24180 4abbb40e3438910efbae5590b6818aae 387 SUPERFAMILY SSF53901 5 230 1.73E-41 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_24180 4abbb40e3438910efbae5590b6818aae 387 Pfam PF00108 Thiolase, N-terminal domain 6 224 1.0E-17 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 STK_24180 4abbb40e3438910efbae5590b6818aae 387 PIRSF PIRSF000429 1 386 1.8E-59 T 23-10-2018 IPR002155 Thiolase GO:0016747 STK_24180 4abbb40e3438910efbae5590b6818aae 387 Pfam PF02803 Thiolase, C-terminal domain 263 357 5.0E-7 T 23-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 STK_18060 2788a4207578869a19456f7d2dcb66b4 143 Pfam PF00571 CBS domain 69 122 4.6E-13 T 23-10-2018 IPR000644 CBS domain STK_18060 2788a4207578869a19456f7d2dcb66b4 143 Pfam PF00571 CBS domain 10 60 1.5E-11 T 23-10-2018 IPR000644 CBS domain STK_18060 2788a4207578869a19456f7d2dcb66b4 143 Gene3D G3DSA:3.10.580.10 2 136 1.7E-35 T 23-10-2018 STK_18060 2788a4207578869a19456f7d2dcb66b4 143 SMART SM00116 77 125 3.5E-9 T 23-10-2018 IPR000644 CBS domain STK_18060 2788a4207578869a19456f7d2dcb66b4 143 SMART SM00116 13 60 8.5E-9 T 23-10-2018 IPR000644 CBS domain STK_18060 2788a4207578869a19456f7d2dcb66b4 143 SUPERFAMILY SSF54631 9 122 1.89E-30 T 23-10-2018 STK_05230 24a7d26949a5c7f5034581e14bb02903 419 Pfam PF13641 Glycosyltransferase like family 2 44 262 1.4E-25 T 23-10-2018 STK_05230 24a7d26949a5c7f5034581e14bb02903 419 SUPERFAMILY SSF53448 42 329 2.16E-45 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_05230 24a7d26949a5c7f5034581e14bb02903 419 Gene3D G3DSA:3.90.550.10 22 248 3.3E-37 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_12050 aaf7a84e87a0155043311d16ab7c542c 139 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 56 85 - T 23-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 STK_12050 aaf7a84e87a0155043311d16ab7c542c 139 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 14 135 1.8E-43 T 23-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 STK_12050 aaf7a84e87a0155043311d16ab7c542c 139 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 13 134 37.233 T 23-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 STK_12050 aaf7a84e87a0155043311d16ab7c542c 139 Gene3D G3DSA:2.40.50.100 3 134 2.2E-50 T 23-10-2018 STK_12050 aaf7a84e87a0155043311d16ab7c542c 139 SUPERFAMILY SSF51230 12 135 1.05E-42 T 23-10-2018 IPR011053 Single hybrid motif STK_12050 aaf7a84e87a0155043311d16ab7c542c 139 Pfam PF01597 Glycine cleavage H-protein 16 135 2.4E-45 T 23-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate STK_19180 221befc3623a8fc350ecfef8939e7031 547 SUPERFAMILY SSF161098 41 248 2.88E-36 T 23-10-2018 IPR035906 MetI-like superfamily STK_19180 221befc3623a8fc350ecfef8939e7031 547 Gene3D G3DSA:1.10.3720.10 270 532 2.5E-27 T 23-10-2018 IPR035906 MetI-like superfamily STK_19180 221befc3623a8fc350ecfef8939e7031 547 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 62 253 8.3E-11 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 STK_19180 221befc3623a8fc350ecfef8939e7031 547 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 352 536 2.4E-9 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 STK_19180 221befc3623a8fc350ecfef8939e7031 547 Gene3D G3DSA:1.10.3720.10 29 260 1.1E-37 T 23-10-2018 IPR035906 MetI-like superfamily STK_19180 221befc3623a8fc350ecfef8939e7031 547 SUPERFAMILY SSF161098 273 546 6.8E-38 T 23-10-2018 IPR035906 MetI-like superfamily STK_21400 d16547527e3ca3d5947d6e7cf70a3abc 371 Gene3D G3DSA:3.90.1150.10 14 360 1.1E-92 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 STK_21400 d16547527e3ca3d5947d6e7cf70a3abc 371 Gene3D G3DSA:3.40.640.10 29 282 1.1E-92 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 STK_21400 d16547527e3ca3d5947d6e7cf70a3abc 371 Pfam PF00266 Aminotransferase class-V 18 343 2.6E-44 T 23-10-2018 IPR000192 Aminotransferase class V domain STK_21400 d16547527e3ca3d5947d6e7cf70a3abc 371 SUPERFAMILY SSF53383 7 368 2.6E-73 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase STK_02370 93554add454a0a6eda0a916c4d072063 531 Hamap MF_01227 CTP synthase [pyrG]. 2 531 50.288 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 STK_02370 93554add454a0a6eda0a916c4d072063 531 SUPERFAMILY SSF52317 289 529 1.49E-77 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_02370 93554add454a0a6eda0a916c4d072063 531 SUPERFAMILY SSF52540 2 270 3.94E-117 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_02370 93554add454a0a6eda0a916c4d072063 531 Gene3D G3DSA:3.40.50.880 287 531 3.7E-106 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_02370 93554add454a0a6eda0a916c4d072063 531 Gene3D G3DSA:3.40.50.300 1 286 2.0E-131 T 23-10-2018 STK_02370 93554add454a0a6eda0a916c4d072063 531 Pfam PF06418 CTP synthase N-terminus 3 267 3.7E-120 T 23-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 STK_02370 93554add454a0a6eda0a916c4d072063 531 TIGRFAM TIGR00337 PyrG: CTP synthase 2 527 5.9E-231 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 STK_02370 93554add454a0a6eda0a916c4d072063 531 Pfam PF00117 Glutamine amidotransferase class-I 302 526 1.8E-54 T 23-10-2018 IPR017926 Glutamine amidotransferase STK_07460 a1109abee7c1aa739d4ca488403d9a21 126 SUPERFAMILY SSF81593 4 121 1.92E-35 T 23-10-2018 STK_07460 a1109abee7c1aa739d4ca488403d9a21 126 Gene3D G3DSA:1.20.120.330 2 122 5.8E-31 T 23-10-2018 STK_07460 a1109abee7c1aa739d4ca488403d9a21 126 Pfam PF05168 HEPN domain 4 120 2.0E-31 T 23-10-2018 IPR007842 HEPN domain STK_07460 a1109abee7c1aa739d4ca488403d9a21 126 SMART SM00748 7 114 6.3E-42 T 23-10-2018 IPR007842 HEPN domain STK_14840 7b0639e511ef26015a5eb95ef5abb413 343 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 12 55 3.2E-10 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_14840 7b0639e511ef26015a5eb95ef5abb413 343 Pfam PF01895 PhoU domain 144 233 1.5E-17 T 23-10-2018 IPR026022 PhoU domain STK_14840 7b0639e511ef26015a5eb95ef5abb413 343 Gene3D G3DSA:1.20.58.220 139 242 2.4E-18 T 23-10-2018 IPR038078 PhoU-like domain superfamily STK_14840 7b0639e511ef26015a5eb95ef5abb413 343 SMART SM00966 11 57 7.8E-9 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_14840 7b0639e511ef26015a5eb95ef5abb413 343 SUPERFAMILY SSF109755 134 331 3.14E-29 T 23-10-2018 STK_18210 6a5787c981d2803db480727309e0688a 350 PIRSF PIRSF026782 3 350 4.7E-118 T 23-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 STK_18210 6a5787c981d2803db480727309e0688a 350 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 6 347 28.113 T 23-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 STK_18210 6a5787c981d2803db480727309e0688a 350 Pfam PF01888 CbiD 7 256 1.4E-77 T 23-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 STK_18210 6a5787c981d2803db480727309e0688a 350 SUPERFAMILY SSF111342 5 274 1.16E-75 T 23-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 STK_18210 6a5787c981d2803db480727309e0688a 350 Gene3D G3DSA:3.30.2110.10 8 174 7.4E-41 T 23-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 STK_18210 6a5787c981d2803db480727309e0688a 350 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 14 345 2.3E-68 T 23-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 STK_08030 a34d066350222421a14626c5f0669aaa 308 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 2 298 6.7E-76 T 23-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain STK_08030 a34d066350222421a14626c5f0669aaa 308 SUPERFAMILY SSF53590 1 305 1.2E-94 T 23-10-2018 IPR036452 Ribonucleoside hydrolase-like STK_08030 a34d066350222421a14626c5f0669aaa 308 Gene3D G3DSA:3.90.245.10 1 308 6.2E-111 T 23-10-2018 IPR036452 Ribonucleoside hydrolase-like STK_14935 09f5c749e339bea1a46c7c398dd868ac 89 SUPERFAMILY SSF82697 3 83 2.62E-18 T 23-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 STK_14935 09f5c749e339bea1a46c7c398dd868ac 89 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 3 81 9.4E-11 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 STK_14935 09f5c749e339bea1a46c7c398dd868ac 89 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 3 81 16.553 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 STK_14935 09f5c749e339bea1a46c7c398dd868ac 89 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 12 79 2.0E-5 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 STK_14935 09f5c749e339bea1a46c7c398dd868ac 89 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 5 80 8.1E-19 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 STK_14935 09f5c749e339bea1a46c7c398dd868ac 89 Gene3D G3DSA:3.30.1280.10 1 89 2.1E-37 T 23-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 STK_04215 b309327e72fde69bbe2c02424b610137 85 Gene3D G3DSA:2.30.30.30 1 85 4.5E-21 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 STK_04215 b309327e72fde69bbe2c02424b610137 85 Pfam PF16906 Ribosomal proteins L26 eukaryotic, L24P archaeal 23 67 1.8E-14 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04215 b309327e72fde69bbe2c02424b610137 85 SUPERFAMILY SSF50104 9 65 8.27E-12 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily STK_04215 b309327e72fde69bbe2c02424b610137 85 TIGRFAM TIGR01080 rplX_A_E: ribosomal protein uL24 1 67 4.7E-17 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_02870 54068e05363df034e0d2deb8972bce3c 306 SUPERFAMILY SSF55326 24 124 1.19E-17 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily STK_02870 54068e05363df034e0d2deb8972bce3c 306 Gene3D G3DSA:3.90.650.10 132 303 5.7E-19 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily STK_02870 54068e05363df034e0d2deb8972bce3c 306 Pfam PF00586 AIR synthase related protein, N-terminal domain 32 123 2.6E-12 T 23-10-2018 IPR016188 PurM-like, N-terminal domain STK_02870 54068e05363df034e0d2deb8972bce3c 306 SUPERFAMILY SSF56042 132 284 1.24E-19 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily STK_02870 54068e05363df034e0d2deb8972bce3c 306 Gene3D G3DSA:3.30.1330.10 2 126 1.9E-18 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily STK_11130 fbb96aea0d2dd01e6d882adc49ab6b08 426 SUPERFAMILY SSF53187 5 424 2.19E-53 T 23-10-2018 STK_11130 fbb96aea0d2dd01e6d882adc49ab6b08 426 Pfam PF01546 Peptidase family M20/M25/M40 72 420 5.7E-37 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 STK_11130 fbb96aea0d2dd01e6d882adc49ab6b08 426 Gene3D G3DSA:3.40.630.10 17 411 1.4E-140 T 23-10-2018 STK_11130 fbb96aea0d2dd01e6d882adc49ab6b08 426 Gene3D G3DSA:3.30.70.360 179 336 1.4E-140 T 23-10-2018 STK_11130 fbb96aea0d2dd01e6d882adc49ab6b08 426 Pfam PF07687 Peptidase dimerisation domain 177 327 9.4E-19 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain STK_04390 19506c505891365ee62d8641eaba0713 232 Gene3D G3DSA:1.10.150.20 142 213 8.6E-18 T 23-10-2018 STK_04390 19506c505891365ee62d8641eaba0713 232 SMART SM00891 3 83 1.5E-27 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 STK_04390 19506c505891365ee62d8641eaba0713 232 SUPERFAMILY SSF52980 3 128 2.95E-32 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 STK_04390 19506c505891365ee62d8641eaba0713 232 Pfam PF02732 ERCC4 domain 7 126 7.0E-25 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 STK_04390 19506c505891365ee62d8641eaba0713 232 SUPERFAMILY SSF47781 151 221 2.38E-15 T 23-10-2018 IPR010994 RuvA domain 2-like STK_04390 19506c505891365ee62d8641eaba0713 232 Gene3D G3DSA:3.40.50.10130 1 141 1.5E-41 T 23-10-2018 STK_12260 fc4f9494b85e820b53aeb8f367e72d38 246 Pfam PF00218 Indole-3-glycerol phosphate synthase 25 241 4.7E-73 T 23-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 STK_12260 fc4f9494b85e820b53aeb8f367e72d38 246 Gene3D G3DSA:3.20.20.70 1 246 5.2E-91 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_12260 fc4f9494b85e820b53aeb8f367e72d38 246 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 30 246 35.426 T 23-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 STK_12260 fc4f9494b85e820b53aeb8f367e72d38 246 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 46 64 - T 23-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 STK_12260 fc4f9494b85e820b53aeb8f367e72d38 246 SUPERFAMILY SSF51366 34 241 2.12E-67 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 STK_09920 8d061b98b86bc17a1203661ad120285b 143 Pfam PF13527 Acetyltransferase (GNAT) domain 3 116 2.0E-12 T 23-10-2018 STK_09920 8d061b98b86bc17a1203661ad120285b 143 Gene3D G3DSA:3.40.630.30 1 118 1.3E-24 T 23-10-2018 STK_09920 8d061b98b86bc17a1203661ad120285b 143 SUPERFAMILY SSF55729 1 127 1.34E-26 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase STK_07730 1cf80c0077fe0fb6275f11a46c28e1b4 384 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 306 314 - T 23-10-2018 IPR018120 Glycoside hydrolase family 1, active site STK_07730 1cf80c0077fe0fb6275f11a46c28e1b4 384 Pfam PF00232 Glycosyl hydrolase family 1 235 380 1.2E-22 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 STK_07730 1cf80c0077fe0fb6275f11a46c28e1b4 384 Pfam PF00232 Glycosyl hydrolase family 1 44 222 3.0E-27 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 STK_07730 1cf80c0077fe0fb6275f11a46c28e1b4 384 Gene3D G3DSA:3.20.20.80 2 383 5.7E-86 T 23-10-2018 STK_07730 1cf80c0077fe0fb6275f11a46c28e1b4 384 PRINTS PR00131 Glycosyl hydrolase family 1 signature 240 254 5.3E-13 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 STK_07730 1cf80c0077fe0fb6275f11a46c28e1b4 384 PRINTS PR00131 Glycosyl hydrolase family 1 signature 360 372 5.3E-13 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 STK_07730 1cf80c0077fe0fb6275f11a46c28e1b4 384 PRINTS PR00131 Glycosyl hydrolase family 1 signature 306 314 5.3E-13 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 STK_07730 1cf80c0077fe0fb6275f11a46c28e1b4 384 PRINTS PR00131 Glycosyl hydrolase family 1 signature 336 353 5.3E-13 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 STK_07730 1cf80c0077fe0fb6275f11a46c28e1b4 384 SUPERFAMILY SSF51445 3 381 8.64E-89 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily STK_21540 1c95e7ddc59c3fde274961c0cb8bfc53 175 Gene3D G3DSA:3.90.79.10 1 169 5.4E-49 T 23-10-2018 STK_21540 1c95e7ddc59c3fde274961c0cb8bfc53 175 SUPERFAMILY SSF55811 3 163 1.49E-44 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 STK_21540 1c95e7ddc59c3fde274961c0cb8bfc53 175 ProSitePatterns PS00893 Nudix box signature. 66 87 - T 23-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 STK_21540 1c95e7ddc59c3fde274961c0cb8bfc53 175 Pfam PF00293 NUDIX domain 31 141 2.7E-16 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 STK_07230 b88da8abab5ce5477d585aa97199162b 156 SUPERFAMILY SSF50475 6 154 1.82E-37 T 23-10-2018 STK_07230 b88da8abab5ce5477d585aa97199162b 156 SMART SM00903 9 152 4.2E-37 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 STK_07230 b88da8abab5ce5477d585aa97199162b 156 Pfam PF01613 Flavin reductase like domain 9 153 1.6E-28 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 STK_07230 b88da8abab5ce5477d585aa97199162b 156 Gene3D G3DSA:2.30.110.10 1 156 5.5E-43 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 STK_01500 b77206cb376ec17b2357125d35745c5f 451 PIRSF PIRSF006060 1 449 2.8E-62 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_01500 b77206cb376ec17b2357125d35745c5f 451 Gene3D G3DSA:1.20.1740.10 6 451 2.1E-36 T 23-10-2018 STK_01500 b77206cb376ec17b2357125d35745c5f 451 Pfam PF00324 Amino acid permease 17 433 1.9E-24 T 23-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 STK_22640 ffebc8079262b35de99db69552228a61 176 PIRSF PIRSF005590 1 174 6.6E-69 T 23-10-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_22640 ffebc8079262b35de99db69552228a61 176 Pfam PF00252 Ribosomal protein L16p/L10e 15 164 6.7E-34 T 23-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 STK_22640 ffebc8079262b35de99db69552228a61 176 ProSitePatterns PS01257 Ribosomal protein L10e signature. 106 127 - T 23-10-2018 IPR018255 Ribosomal protein L10e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_22640 ffebc8079262b35de99db69552228a61 176 Hamap MF_00448 50S ribosomal protein L10e [rpl10e]. 1 176 36.785 T 23-10-2018 IPR022981 Ribosomal protein L10e, archaea STK_22640 ffebc8079262b35de99db69552228a61 176 SUPERFAMILY SSF54686 4 167 1.96E-56 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 STK_22640 ffebc8079262b35de99db69552228a61 176 Gene3D G3DSA:3.90.1170.10 4 172 2.6E-64 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 STK_11360 6798b13dcbd50fe3881aa522f093c45f 471 Pfam PF00005 ABC transporter 23 171 3.3E-23 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_11360 6798b13dcbd50fe3881aa522f093c45f 471 SUPERFAMILY SSF52540 263 460 1.09E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_11360 6798b13dcbd50fe3881aa522f093c45f 471 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 STK_11360 6798b13dcbd50fe3881aa522f093c45f 471 Pfam PF00005 ABC transporter 281 412 5.2E-23 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_11360 6798b13dcbd50fe3881aa522f093c45f 471 Gene3D G3DSA:3.40.50.300 260 470 6.1E-42 T 23-10-2018 STK_11360 6798b13dcbd50fe3881aa522f093c45f 471 SUPERFAMILY SSF52540 3 229 4.72E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_11360 6798b13dcbd50fe3881aa522f093c45f 471 ProSitePatterns PS00211 ABC transporters family signature. 385 399 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 STK_11360 6798b13dcbd50fe3881aa522f093c45f 471 Gene3D G3DSA:3.40.50.300 3 259 1.9E-55 T 23-10-2018 STK_11360 6798b13dcbd50fe3881aa522f093c45f 471 SMART SM00382 29 218 2.3E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_11360 6798b13dcbd50fe3881aa522f093c45f 471 SMART SM00382 278 458 3.7E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_02910 2f395a852781ca7325978a688047c126 335 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 9 16 - T 23-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 STK_02910 2f395a852781ca7325978a688047c126 335 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 314 327 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 STK_02910 2f395a852781ca7325978a688047c126 335 Gene3D G3DSA:3.40.440.10 2 334 5.9E-102 T 23-10-2018 STK_02910 2f395a852781ca7325978a688047c126 335 Pfam PF00709 Adenylosuccinate synthetase 144 283 4.2E-36 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 STK_02910 2f395a852781ca7325978a688047c126 335 Pfam PF00709 Adenylosuccinate synthetase 4 137 9.1E-21 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 STK_02910 2f395a852781ca7325978a688047c126 335 Pfam PF00709 Adenylosuccinate synthetase 286 328 9.2E-7 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 STK_02910 2f395a852781ca7325978a688047c126 335 SUPERFAMILY SSF52540 3 330 6.05E-86 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_02910 2f395a852781ca7325978a688047c126 335 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 335 67.203 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 STK_02910 2f395a852781ca7325978a688047c126 335 SMART SM00788 2 329 2.1E-124 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 STK_20180 77a7f18bda039c3c3ca6625fb7bf09be 122 SUPERFAMILY SSF53146 1 119 7.46E-27 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily STK_20180 77a7f18bda039c3c3ca6625fb7bf09be 122 Gene3D G3DSA:3.30.420.130 1 120 8.4E-34 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily STK_20180 77a7f18bda039c3c3ca6625fb7bf09be 122 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 16 100 6.7E-13 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis STK_04010 71000f0886bee1388c4efa36f20d3d8b 911 SUPERFAMILY SSF52540 34 389 6.44E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_04010 71000f0886bee1388c4efa36f20d3d8b 911 Pfam PF00271 Helicase conserved C-terminal domain 244 345 2.0E-19 T 23-10-2018 IPR001650 Helicase, C-terminal STK_04010 71000f0886bee1388c4efa36f20d3d8b 911 PIRSF PIRSF037307 1 911 0.0 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 STK_04010 71000f0886bee1388c4efa36f20d3d8b 911 Gene3D G3DSA:3.40.50.300 235 377 4.5E-29 T 23-10-2018 STK_04010 71000f0886bee1388c4efa36f20d3d8b 911 Pfam PF00270 DEAD/DEAH box helicase 21 188 1.4E-32 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 STK_04010 71000f0886bee1388c4efa36f20d3d8b 911 Gene3D G3DSA:3.40.50.300 2 208 8.0E-48 T 23-10-2018 STK_04010 71000f0886bee1388c4efa36f20d3d8b 911 SUPERFAMILY SSF52540 5 201 3.69E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_04010 71000f0886bee1388c4efa36f20d3d8b 911 SMART SM00490 266 345 2.7E-19 T 23-10-2018 IPR001650 Helicase, C-terminal STK_04010 71000f0886bee1388c4efa36f20d3d8b 911 Pfam PF08494 DEAD/H associated 584 754 3.5E-17 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 STK_04010 71000f0886bee1388c4efa36f20d3d8b 911 SMART SM00487 16 215 2.8E-43 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain STK_02508 f28c2b5d25e81f832288be9dbc24e479 95 SUPERFAMILY SSF143011 5 91 1.47E-10 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily STK_02508 f28c2b5d25e81f832288be9dbc24e479 95 Gene3D G3DSA:3.30.2310.20 5 95 9.5E-13 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily STK_25730 dccc600e0be16fe649e9a53e64710762 341 Gene3D G3DSA:3.50.50.100 1 334 4.2E-60 T 23-10-2018 STK_25730 dccc600e0be16fe649e9a53e64710762 341 SUPERFAMILY SSF51905 1 272 5.62E-27 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_25730 dccc600e0be16fe649e9a53e64710762 341 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 269 1.4E-42 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 STK_25730 dccc600e0be16fe649e9a53e64710762 341 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.6E-6 T 23-10-2018 STK_25730 dccc600e0be16fe649e9a53e64710762 341 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 124 142 1.6E-6 T 23-10-2018 STK_25730 dccc600e0be16fe649e9a53e64710762 341 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 177 193 7.2E-6 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_25730 dccc600e0be16fe649e9a53e64710762 341 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 2 24 7.2E-6 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_25730 dccc600e0be16fe649e9a53e64710762 341 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 120 144 7.2E-6 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_03840 eb48b34a18a7af2f79bee5dca2f9263e 153 SMART SM01386 2 58 2.1E-26 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_03840 eb48b34a18a7af2f79bee5dca2f9263e 153 SMART SM01387 68 147 3.4E-15 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_03840 eb48b34a18a7af2f79bee5dca2f9263e 153 Pfam PF08069 Ribosomal S13/S15 N-terminal domain 4 58 1.2E-22 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_03840 eb48b34a18a7af2f79bee5dca2f9263e 153 ProSitePatterns PS00362 Ribosomal protein S15 signature. 96 126 - T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_03840 eb48b34a18a7af2f79bee5dca2f9263e 153 Gene3D G3DSA:1.10.8.1030 34 80 3.9E-22 T 23-10-2018 STK_03840 eb48b34a18a7af2f79bee5dca2f9263e 153 Pfam PF00312 Ribosomal protein S15 71 146 2.1E-15 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_03840 eb48b34a18a7af2f79bee5dca2f9263e 153 Hamap MF_01343_A 30S ribosomal protein S15 [rpsO]. 1 147 34.719 T 23-10-2018 IPR023029 Ribosomal protein S15P Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_03840 eb48b34a18a7af2f79bee5dca2f9263e 153 SUPERFAMILY SSF47060 64 141 1.09E-19 T 23-10-2018 IPR009068 S15/NS1, RNA-binding STK_03840 eb48b34a18a7af2f79bee5dca2f9263e 153 Gene3D G3DSA:1.10.287.10 81 149 6.9E-28 T 23-10-2018 STK_02100 2586e1190195b7ac93f112f29555abf6 351 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 141 158 1.0E-29 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 STK_02100 2586e1190195b7ac93f112f29555abf6 351 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 162 182 1.0E-29 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 STK_02100 2586e1190195b7ac93f112f29555abf6 351 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 21 35 1.0E-29 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 STK_02100 2586e1190195b7ac93f112f29555abf6 351 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 228 243 1.0E-29 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 STK_02100 2586e1190195b7ac93f112f29555abf6 351 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 75 94 1.0E-29 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 STK_02100 2586e1190195b7ac93f112f29555abf6 351 TIGRFAM TIGR03674 fen_arch: flap structure-specific endonuclease 1 351 2.7E-133 T 23-10-2018 IPR019973 Flap structure-specific endonuclease, archaea GO:0016788 STK_02100 2586e1190195b7ac93f112f29555abf6 351 SMART SM00485 1 101 3.6E-42 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 STK_02100 2586e1190195b7ac93f112f29555abf6 351 SUPERFAMILY SSF47807 223 351 2.39E-26 T 23-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily STK_02100 2586e1190195b7ac93f112f29555abf6 351 ProSitePatterns PS00841 XPG protein signature 1. 73 87 - T 23-10-2018 IPR019974 XPG conserved site GO:0016788 STK_02100 2586e1190195b7ac93f112f29555abf6 351 SUPERFAMILY SSF88723 2 238 7.2E-63 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_02100 2586e1190195b7ac93f112f29555abf6 351 SMART SM00279 225 259 4.3E-8 T 23-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 STK_02100 2586e1190195b7ac93f112f29555abf6 351 SMART SM00484 142 223 1.1E-31 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 STK_02100 2586e1190195b7ac93f112f29555abf6 351 Pfam PF00867 XPG I-region 143 238 5.0E-26 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 STK_02100 2586e1190195b7ac93f112f29555abf6 351 Hamap MF_00614 Flap endonuclease 1 [fen]. 1 351 136.112 T 23-10-2018 IPR023426 Flap endonuclease 1 GO:0016788 Reactome: R-HSA-110362|Reactome: R-HSA-162594|Reactome: R-HSA-174437|Reactome: R-HSA-5651801|Reactome: R-HSA-5685939|Reactome: R-HSA-69166 STK_02100 2586e1190195b7ac93f112f29555abf6 351 Pfam PF00752 XPG N-terminal domain 3 100 9.2E-21 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 STK_12150 a5c63c95731afbcee67aa81a1bbfff68 369 SUPERFAMILY SSF116846 6 75 5.62E-14 T 23-10-2018 IPR036181 MIT domain superfamily STK_12150 a5c63c95731afbcee67aa81a1bbfff68 369 Pfam PF04212 MIT (microtubule interacting and transport) domain 11 73 2.5E-11 T 23-10-2018 IPR007330 MIT STK_12150 a5c63c95731afbcee67aa81a1bbfff68 369 SMART SM00745 4 79 1.5E-13 T 23-10-2018 IPR007330 MIT STK_12150 a5c63c95731afbcee67aa81a1bbfff68 369 Pfam PF09336 Vps4 C terminal oligomerisation domain 327 366 6.2E-8 T 23-10-2018 IPR015415 Vps4 oligomerisation, C-terminal STK_12150 a5c63c95731afbcee67aa81a1bbfff68 369 Gene3D G3DSA:1.10.8.60 271 369 1.0E-25 T 23-10-2018 STK_12150 a5c63c95731afbcee67aa81a1bbfff68 369 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 135 269 6.6E-40 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_12150 a5c63c95731afbcee67aa81a1bbfff68 369 SUPERFAMILY SSF52540 96 366 1.14E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_12150 a5c63c95731afbcee67aa81a1bbfff68 369 Gene3D G3DSA:1.20.58.280 1 82 1.8E-29 T 23-10-2018 STK_12150 a5c63c95731afbcee67aa81a1bbfff68 369 SMART SM00382 131 272 3.1E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_12150 a5c63c95731afbcee67aa81a1bbfff68 369 Gene3D G3DSA:3.40.50.300 88 270 1.3E-65 T 23-10-2018 STK_09940 5057c72a76b4daec6f18f183c37efdb9 108 Pfam PF13635 Domain of unknown function (DUF4143) 14 99 2.5E-9 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 STK_03490 a3b5ec4e1fd81a349958e74d9cc4b618 308 Pfam PF08271 TFIIB zinc-binding 15 51 6.7E-11 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type STK_03490 a3b5ec4e1fd81a349958e74d9cc4b618 308 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 252 267 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 STK_03490 a3b5ec4e1fd81a349958e74d9cc4b618 308 PRINTS PR00685 Transcription initiation factor IIB signature 219 237 1.5E-55 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 STK_03490 a3b5ec4e1fd81a349958e74d9cc4b618 308 PRINTS PR00685 Transcription initiation factor IIB signature 58 79 1.5E-55 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 STK_03490 a3b5ec4e1fd81a349958e74d9cc4b618 308 PRINTS PR00685 Transcription initiation factor IIB signature 253 269 1.5E-55 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 STK_03490 a3b5ec4e1fd81a349958e74d9cc4b618 308 PRINTS PR00685 Transcription initiation factor IIB signature 45 58 1.5E-55 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 STK_03490 a3b5ec4e1fd81a349958e74d9cc4b618 308 PRINTS PR00685 Transcription initiation factor IIB signature 23 43 1.5E-55 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 STK_03490 a3b5ec4e1fd81a349958e74d9cc4b618 308 PRINTS PR00685 Transcription initiation factor IIB signature 285 299 1.5E-55 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 STK_03490 a3b5ec4e1fd81a349958e74d9cc4b618 308 PRINTS PR00685 Transcription initiation factor IIB signature 166 185 1.5E-55 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 STK_03490 a3b5ec4e1fd81a349958e74d9cc4b618 308 PRINTS PR00685 Transcription initiation factor IIB signature 192 207 1.5E-55 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 STK_03490 a3b5ec4e1fd81a349958e74d9cc4b618 308 SUPERFAMILY SSF47954 215 307 5.85E-30 T 23-10-2018 IPR036915 Cyclin-like superfamily STK_03490 a3b5ec4e1fd81a349958e74d9cc4b618 308 SUPERFAMILY SSF57783 14 54 7.06E-11 T 23-10-2018 STK_03490 a3b5ec4e1fd81a349958e74d9cc4b618 308 Gene3D G3DSA:1.10.472.10 215 307 3.6E-26 T 23-10-2018 STK_03490 a3b5ec4e1fd81a349958e74d9cc4b618 308 SUPERFAMILY SSF47954 118 213 2.1E-26 T 23-10-2018 IPR036915 Cyclin-like superfamily STK_03490 a3b5ec4e1fd81a349958e74d9cc4b618 308 Gene3D G3DSA:1.10.472.170 12 207 2.4E-62 T 23-10-2018 STK_03490 a3b5ec4e1fd81a349958e74d9cc4b618 308 Pfam PF00382 Transcription factor TFIIB repeat 221 290 1.6E-16 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 STK_03490 a3b5ec4e1fd81a349958e74d9cc4b618 308 Pfam PF00382 Transcription factor TFIIB repeat 128 195 2.6E-17 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 STK_03490 a3b5ec4e1fd81a349958e74d9cc4b618 308 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 5 305 43.764 T 23-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea STK_03490 a3b5ec4e1fd81a349958e74d9cc4b618 308 SMART SM00385 124 205 1.1E-10 T 23-10-2018 IPR013763 Cyclin-like STK_03490 a3b5ec4e1fd81a349958e74d9cc4b618 308 SMART SM00385 218 299 4.8E-12 T 23-10-2018 IPR013763 Cyclin-like STK_03490 a3b5ec4e1fd81a349958e74d9cc4b618 308 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 158 173 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 STK_21910 a78c79ecd07e5ed5dbf9d647725d1046 133 SUPERFAMILY SSF88723 3 131 3.08E-19 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_21910 a78c79ecd07e5ed5dbf9d647725d1046 133 Pfam PF01850 PIN domain 5 123 2.2E-15 T 23-10-2018 IPR002716 PIN domain STK_21910 a78c79ecd07e5ed5dbf9d647725d1046 133 Gene3D G3DSA:3.40.50.1010 2 128 1.5E-12 T 23-10-2018 STK_02450 9dce2ee0334abbfb62206a3baf76203b 445 SUPERFAMILY SSF51998 4 438 3.57E-132 T 23-10-2018 STK_02450 9dce2ee0334abbfb62206a3baf76203b 445 Gene3D G3DSA:3.20.70.20 3 443 2.0E-138 T 23-10-2018 STK_02450 9dce2ee0334abbfb62206a3baf76203b 445 Hamap MF_01221 UPF0210 protein . 3 445 46.814 T 23-10-2018 IPR007841 Uncharacterised protein family UPF0210 STK_02450 9dce2ee0334abbfb62206a3baf76203b 445 Pfam PF05167 Uncharacterised ACR (DUF711) 14 399 5.6E-125 T 23-10-2018 IPR007841 Uncharacterised protein family UPF0210 STK_11090 adeea34a7a648a0058dc5be5a9624a92 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 STK_11090 adeea34a7a648a0058dc5be5a9624a92 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.3E-49 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_11090 adeea34a7a648a0058dc5be5a9624a92 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 1.3E-49 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_11090 adeea34a7a648a0058dc5be5a9624a92 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.3E-49 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_11090 adeea34a7a648a0058dc5be5a9624a92 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.3E-49 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_11090 adeea34a7a648a0058dc5be5a9624a92 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.3E-49 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_11090 adeea34a7a648a0058dc5be5a9624a92 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.3E-49 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_11090 adeea34a7a648a0058dc5be5a9624a92 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 248 1.1E-67 T 23-10-2018 STK_11090 adeea34a7a648a0058dc5be5a9624a92 250 SUPERFAMILY SSF51735 6 249 3.92E-88 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_11090 adeea34a7a648a0058dc5be5a9624a92 250 Gene3D G3DSA:3.40.50.720 3 250 8.4E-89 T 23-10-2018 STK_11090 adeea34a7a648a0058dc5be5a9624a92 250 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 10 249 3.7E-90 T 23-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 STK_11090 adeea34a7a648a0058dc5be5a9624a92 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 5.8E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_11090 adeea34a7a648a0058dc5be5a9624a92 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 5.8E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_11090 adeea34a7a648a0058dc5be5a9624a92 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 5.8E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_21520 0f4b4f5d622dc40fd20f62ff1bf4469e 150 PRINTS PR00332 Histidine triad family signature 3 19 2.4E-11 T 23-10-2018 IPR001310 Histidine triad (HIT) protein STK_21520 0f4b4f5d622dc40fd20f62ff1bf4469e 150 PRINTS PR00332 Histidine triad family signature 91 101 2.4E-11 T 23-10-2018 IPR001310 Histidine triad (HIT) protein STK_21520 0f4b4f5d622dc40fd20f62ff1bf4469e 150 PRINTS PR00332 Histidine triad family signature 24 42 2.4E-11 T 23-10-2018 IPR001310 Histidine triad (HIT) protein STK_21520 0f4b4f5d622dc40fd20f62ff1bf4469e 150 Pfam PF01230 HIT domain 11 103 6.6E-24 T 23-10-2018 IPR001310 Histidine triad (HIT) protein STK_21520 0f4b4f5d622dc40fd20f62ff1bf4469e 150 SUPERFAMILY SSF54197 1 132 1.86E-39 T 23-10-2018 IPR036265 HIT-like superfamily STK_21520 0f4b4f5d622dc40fd20f62ff1bf4469e 150 ProSitePatterns PS00892 HIT domain signature. 84 102 - T 23-10-2018 IPR019808 Histidine triad, conserved site STK_21520 0f4b4f5d622dc40fd20f62ff1bf4469e 150 Gene3D G3DSA:3.30.428.10 2 150 3.3E-49 T 23-10-2018 IPR036265 HIT-like superfamily STK_00530 b043597e117d2d95a9bd9586024a32b5 344 SUPERFAMILY SSF50129 1 175 1.38E-49 T 23-10-2018 IPR011032 GroES-like superfamily STK_00530 b043597e117d2d95a9bd9586024a32b5 344 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 65 79 - T 23-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 STK_00530 b043597e117d2d95a9bd9586024a32b5 344 Gene3D G3DSA:3.40.50.720 152 293 1.9E-108 T 23-10-2018 STK_00530 b043597e117d2d95a9bd9586024a32b5 344 SUPERFAMILY SSF51735 141 316 2.87E-39 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_00530 b043597e117d2d95a9bd9586024a32b5 344 SMART SM00829 10 342 2.1E-9 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 STK_00530 b043597e117d2d95a9bd9586024a32b5 344 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 138 4.1E-31 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 STK_00530 b043597e117d2d95a9bd9586024a32b5 344 Gene3D G3DSA:3.90.180.10 15 335 1.9E-108 T 23-10-2018 STK_00530 b043597e117d2d95a9bd9586024a32b5 344 Pfam PF00107 Zinc-binding dehydrogenase 179 307 2.2E-24 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 STK_09340 0b7da4adcd67b2e6c8304e9e82244f07 321 Gene3D G3DSA:1.20.1250.20 1 312 2.1E-36 T 23-10-2018 STK_09340 0b7da4adcd67b2e6c8304e9e82244f07 321 PRINTS PR01035 Tetracycline resistance protein signature 3 27 6.7E-5 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 STK_09340 0b7da4adcd67b2e6c8304e9e82244f07 321 PRINTS PR01035 Tetracycline resistance protein signature 254 277 6.7E-5 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 STK_09340 0b7da4adcd67b2e6c8304e9e82244f07 321 PRINTS PR01035 Tetracycline resistance protein signature 57 79 6.7E-5 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 STK_09340 0b7da4adcd67b2e6c8304e9e82244f07 321 PRINTS PR01035 Tetracycline resistance protein signature 193 214 6.7E-5 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 STK_09340 0b7da4adcd67b2e6c8304e9e82244f07 321 Pfam PF07690 Major Facilitator Superfamily 2 153 3.5E-12 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_09340 0b7da4adcd67b2e6c8304e9e82244f07 321 SUPERFAMILY SSF103473 2 304 1.31E-41 T 23-10-2018 IPR036259 MFS transporter superfamily STK_09340 0b7da4adcd67b2e6c8304e9e82244f07 321 ProSitePatterns PS00217 Sugar transport proteins signature 2. 32 57 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 STK_04500 59613df1ffa7aa5bd7ba7a083de4b337 215 SMART SM01384 4 186 3.6E-110 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04500 59613df1ffa7aa5bd7ba7a083de4b337 215 ProSitePatterns PS01194 Ribosomal protein L15e signature. 45 68 - T 23-10-2018 IPR020925 Ribosomal protein L15e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04500 59613df1ffa7aa5bd7ba7a083de4b337 215 SUPERFAMILY SSF54189 4 192 3.98E-75 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_04500 59613df1ffa7aa5bd7ba7a083de4b337 215 Pfam PF00827 Ribosomal L15 4 186 1.4E-74 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04500 59613df1ffa7aa5bd7ba7a083de4b337 215 Hamap MF_00256 50S ribosomal protein L15e [rpl15e]. 3 194 39.631 T 23-10-2018 IPR020926 Ribosomal protein L15e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_04500 59613df1ffa7aa5bd7ba7a083de4b337 215 Gene3D G3DSA:3.40.1120.10 2 198 5.3E-74 T 23-10-2018 IPR024794 Ribosomal protein L15e core domain superfamily GO:0003735|GO:0005840 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_10500 77c3c7bc528110254ecba5d62193267f 347 Pfam PF07282 Putative transposase DNA-binding domain 212 280 2.0E-19 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_10500 77c3c7bc528110254ecba5d62193267f 347 Gene3D G3DSA:3.30.420.140 148 258 9.1E-6 T 23-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 STK_10500 77c3c7bc528110254ecba5d62193267f 347 SUPERFAMILY SSF53098 169 243 1.9E-5 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily STK_10500 77c3c7bc528110254ecba5d62193267f 347 Pfam PF01385 Probable transposase 82 197 1.3E-35 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 STK_02820 2fc6ae98374d050f5d16949b99381a56 473 Gene3D G3DSA:1.10.10.410 411 472 1.8E-15 T 23-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal STK_02820 2fc6ae98374d050f5d16949b99381a56 473 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 2 470 2.3E-161 T 23-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 STK_02820 2fc6ae98374d050f5d16949b99381a56 473 Pfam PF02637 GatB domain 324 470 1.8E-43 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 STK_02820 2fc6ae98374d050f5d16949b99381a56 473 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 147 161 - T 23-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 STK_02820 2fc6ae98374d050f5d16949b99381a56 473 Gene3D G3DSA:1.10.150.380 296 409 2.3E-31 T 23-10-2018 STK_02820 2fc6ae98374d050f5d16949b99381a56 473 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 1 471 33.889 T 23-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 STK_02820 2fc6ae98374d050f5d16949b99381a56 473 Pfam PF02934 GatB/GatE catalytic domain 2 285 6.6E-99 T 23-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 STK_02820 2fc6ae98374d050f5d16949b99381a56 473 SMART SM00845 324 470 1.7E-57 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 STK_02820 2fc6ae98374d050f5d16949b99381a56 473 SUPERFAMILY SSF89095 293 399 7.46E-30 T 23-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 STK_02820 2fc6ae98374d050f5d16949b99381a56 473 SUPERFAMILY SSF55931 2 292 1.63E-97 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 STK_05150 6f092273a9dc0075a0fa64e4de75c162 418 Pfam PF04055 Radical SAM superfamily 134 306 1.7E-28 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_05150 6f092273a9dc0075a0fa64e4de75c162 418 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 2 414 4.4E-123 T 23-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 STK_05150 6f092273a9dc0075a0fa64e4de75c162 418 Gene3D G3DSA:3.80.30.20 128 361 4.7E-74 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe STK_05150 6f092273a9dc0075a0fa64e4de75c162 418 Pfam PF00919 Uncharacterized protein family UPF0004 2 93 3.4E-22 T 23-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 STK_05150 6f092273a9dc0075a0fa64e4de75c162 418 Gene3D G3DSA:3.40.50.12160 1 126 2.0E-25 T 23-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily STK_05150 6f092273a9dc0075a0fa64e4de75c162 418 TIGRFAM TIGR01578 MiaB-like-B: MiaB-like tRNA modifying enzyme, archaeal-type 2 416 1.1E-132 T 23-10-2018 IPR006466 MiaB-like tRNA modifying enzyme, archaeal-type Reactome: R-HSA-6782315 STK_05150 6f092273a9dc0075a0fa64e4de75c162 418 SUPERFAMILY SSF102114 113 357 1.44E-53 T 23-10-2018 STK_05150 6f092273a9dc0075a0fa64e4de75c162 418 Pfam PF01938 TRAM domain 360 416 2.8E-9 T 23-10-2018 IPR002792 TRAM domain STK_05150 6f092273a9dc0075a0fa64e4de75c162 418 SMART SM00729 130 347 8.3E-55 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 STK_24150 7bdfeee68f635982b7680fbf3dfa22bd 300 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 11 49 2.2E-6 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_24150 7bdfeee68f635982b7680fbf3dfa22bd 300 SMART SM00966 8 53 3.5E-6 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_12080 29a8f1f789d514b075e631a790ddec79 505 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 11 490 53.511 T 23-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 STK_12080 29a8f1f789d514b075e631a790ddec79 505 Gene3D G3DSA:3.90.1150.10 339 475 3.2E-32 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 STK_12080 29a8f1f789d514b075e631a790ddec79 505 Pfam PF02347 Glycine cleavage system P-protein 37 305 2.0E-10 T 23-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 STK_12080 29a8f1f789d514b075e631a790ddec79 505 SUPERFAMILY SSF53383 40 481 4.51E-96 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase STK_12080 29a8f1f789d514b075e631a790ddec79 505 Gene3D G3DSA:3.40.640.10 88 317 5.9E-53 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 STK_04620 8b06f8a8ab1f8a2e06290122078d7f15 190 Pfam PF02223 Thymidylate kinase 7 177 2.2E-42 T 23-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 STK_04620 8b06f8a8ab1f8a2e06290122078d7f15 190 ProSitePatterns PS01331 Thymidylate kinase signature. 83 95 - T 23-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 STK_04620 8b06f8a8ab1f8a2e06290122078d7f15 190 SUPERFAMILY SSF52540 1 187 9.85E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_04620 8b06f8a8ab1f8a2e06290122078d7f15 190 Hamap MF_00165 Thymidylate kinase [tmk]. 3 187 22.336 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 STK_04620 8b06f8a8ab1f8a2e06290122078d7f15 190 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 3 178 2.7E-45 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 STK_04620 8b06f8a8ab1f8a2e06290122078d7f15 190 Gene3D G3DSA:3.40.50.300 2 187 1.3E-51 T 23-10-2018 STK_21850 fe8230e83f2f2f8ba0362f1f84162a60 312 Hamap MF_00217 Mevalonate kinase [mvk]. 2 306 49.298 T 23-10-2018 IPR022937 Mevalonate kinase, archaeal GO:0004496 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922 STK_21850 fe8230e83f2f2f8ba0362f1f84162a60 312 Gene3D G3DSA:3.30.70.890 174 285 1.6E-63 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily STK_21850 fe8230e83f2f2f8ba0362f1f84162a60 312 SUPERFAMILY SSF54211 2 181 2.88E-39 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold STK_21850 fe8230e83f2f2f8ba0362f1f84162a60 312 Pfam PF08544 GHMP kinases C terminal 219 292 5.1E-8 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain STK_21850 fe8230e83f2f2f8ba0362f1f84162a60 312 Gene3D G3DSA:3.30.230.10 7 173 1.6E-63 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup STK_21850 fe8230e83f2f2f8ba0362f1f84162a60 312 Pfam PF00288 GHMP kinases N terminal domain 91 157 2.7E-10 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 STK_21850 fe8230e83f2f2f8ba0362f1f84162a60 312 PRINTS PR00959 Mevalonate kinase family signature 95 117 9.1E-10 T 23-10-2018 STK_21850 fe8230e83f2f2f8ba0362f1f84162a60 312 PRINTS PR00959 Mevalonate kinase family signature 6 30 9.1E-10 T 23-10-2018 STK_21850 fe8230e83f2f2f8ba0362f1f84162a60 312 PRINTS PR00959 Mevalonate kinase family signature 265 282 9.1E-10 T 23-10-2018 STK_21850 fe8230e83f2f2f8ba0362f1f84162a60 312 SUPERFAMILY SSF55060 172 309 1.79E-23 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily STK_21850 fe8230e83f2f2f8ba0362f1f84162a60 312 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 7 279 1.6E-80 T 23-10-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 STK_07040 3ce3c3b41c589f6c3fe093ec62c1af7d 349 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 139 347 4.9E-31 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 STK_07040 3ce3c3b41c589f6c3fe093ec62c1af7d 349 SUPERFAMILY SSF161098 117 335 1.21E-6 T 23-10-2018 IPR035906 MetI-like superfamily STK_07040 3ce3c3b41c589f6c3fe093ec62c1af7d 349 Gene3D G3DSA:1.10.3720.10 110 340 5.7E-11 T 23-10-2018 IPR035906 MetI-like superfamily STK_09130 915a44fc94a98516833f71e06f66ea2a 166 SUPERFAMILY SSF46785 4 53 3.39E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_09130 915a44fc94a98516833f71e06f66ea2a 166 Gene3D G3DSA:1.10.10.10 3 92 6.1E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_10280 63296bcbbec2016db76140c499fd9594 493 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 231 248 3.9E-28 T 23-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 STK_10280 63296bcbbec2016db76140c499fd9594 493 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 358 371 3.9E-28 T 23-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 STK_10280 63296bcbbec2016db76140c499fd9594 493 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 270 286 3.9E-28 T 23-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 STK_10280 63296bcbbec2016db76140c499fd9594 493 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 332 347 3.9E-28 T 23-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 STK_10280 63296bcbbec2016db76140c499fd9594 493 Pfam PF01979 Amidohydrolase family 62 382 6.7E-59 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 STK_10280 63296bcbbec2016db76140c499fd9594 493 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 1 493 2.0E-216 T 23-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 STK_10280 63296bcbbec2016db76140c499fd9594 493 Hamap MF_01953 Urease subunit alpha [ureC]. 1 493 43.378 T 23-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 STK_10280 63296bcbbec2016db76140c499fd9594 493 Gene3D G3DSA:3.20.20.140 66 493 4.9E-219 T 23-10-2018 STK_10280 63296bcbbec2016db76140c499fd9594 493 SUPERFAMILY SSF51556 66 493 7.74E-170 T 23-10-2018 IPR032466 Metal-dependent hydrolase STK_10280 63296bcbbec2016db76140c499fd9594 493 Pfam PF00449 Urease alpha-subunit, N-terminal domain 1 56 5.2E-17 T 23-10-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 STK_10280 63296bcbbec2016db76140c499fd9594 493 Gene3D G3DSA:2.30.40.10 2 411 4.9E-219 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_10280 63296bcbbec2016db76140c499fd9594 493 SUPERFAMILY SSF51338 2 405 2.47E-35 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_17830 f9f1d97bce951073fd67b585ca659dcf 283 Gene3D G3DSA:3.30.390.50 176 281 4.2E-25 T 23-10-2018 STK_17830 f9f1d97bce951073fd67b585ca659dcf 283 Gene3D G3DSA:3.30.43.10 1 52 5.6E-20 T 23-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 STK_17830 f9f1d97bce951073fd67b585ca659dcf 283 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 179 277 1.8E-19 T 23-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal STK_17830 f9f1d97bce951073fd67b585ca659dcf 283 Gene3D G3DSA:3.30.465.10 56 172 3.4E-39 T 23-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 STK_17830 f9f1d97bce951073fd67b585ca659dcf 283 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 172 7.6E-47 T 23-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 STK_17830 f9f1d97bce951073fd67b585ca659dcf 283 SUPERFAMILY SSF56176 1 172 4.2E-51 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 STK_17830 f9f1d97bce951073fd67b585ca659dcf 283 SUPERFAMILY SSF55447 176 279 1.03E-24 T 23-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily STK_17830 f9f1d97bce951073fd67b585ca659dcf 283 SMART SM01092 178 278 3.6E-25 T 23-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal STK_10250 aa18f0d3e6d03b2e4a65d6d21d97e46a 209 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 4 180 8.3E-31 T 23-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain STK_10250 aa18f0d3e6d03b2e4a65d6d21d97e46a 209 Hamap MF_01389 Urease accessory protein UreG [ureG]. 1 204 38.999 T 23-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 STK_10250 aa18f0d3e6d03b2e4a65d6d21d97e46a 209 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 1 203 9.4E-72 T 23-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 STK_10250 aa18f0d3e6d03b2e4a65d6d21d97e46a 209 Gene3D G3DSA:3.40.50.300 1 204 8.0E-50 T 23-10-2018 STK_10250 aa18f0d3e6d03b2e4a65d6d21d97e46a 209 PIRSF PIRSF005624 1 206 3.3E-54 T 23-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 STK_10250 aa18f0d3e6d03b2e4a65d6d21d97e46a 209 SUPERFAMILY SSF52540 2 200 1.42E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_21840 f1974f0197cc40e590373007523cadaf 356 Gene3D G3DSA:2.160.10.10 205 356 1.2E-27 T 23-10-2018 STK_21840 f1974f0197cc40e590373007523cadaf 356 Gene3D G3DSA:3.90.550.10 1 204 1.2E-26 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_21840 f1974f0197cc40e590373007523cadaf 356 SUPERFAMILY SSF53448 2 290 1.59E-38 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_21840 f1974f0197cc40e590373007523cadaf 356 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 253 287 3.6E-5 T 23-10-2018 IPR001451 Hexapeptide repeat STK_21840 f1974f0197cc40e590373007523cadaf 356 Pfam PF00483 Nucleotidyl transferase 3 183 6.5E-15 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 STK_23270 ee10536f715df87b5f297bd50da9f55f 232 SUPERFAMILY SSF56281 1 232 6.42E-41 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_23270 ee10536f715df87b5f297bd50da9f55f 232 Gene3D G3DSA:3.60.15.10 1 232 3.8E-43 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_23270 ee10536f715df87b5f297bd50da9f55f 232 Pfam PF12706 Beta-lactamase superfamily domain 52 198 1.8E-15 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_23270 ee10536f715df87b5f297bd50da9f55f 232 SMART SM00849 19 205 4.8E-12 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_00440 99ae36da9d176fee1258b42da25e82ff 294 Gene3D G3DSA:3.20.20.140 59 292 8.1E-21 T 23-10-2018 STK_00440 99ae36da9d176fee1258b42da25e82ff 294 Pfam PF04909 Amidohydrolase 17 286 1.2E-22 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 STK_00440 99ae36da9d176fee1258b42da25e82ff 294 SUPERFAMILY SSF51556 15 286 2.15E-26 T 23-10-2018 IPR032466 Metal-dependent hydrolase STK_03770 99dbe5940e53fc6732f5c9d6c6667e0b 413 SUPERFAMILY SSF53649 5 404 1.71E-35 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 STK_03770 99dbe5940e53fc6732f5c9d6c6667e0b 413 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 8 403 3.7E-128 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 STK_03770 99dbe5940e53fc6732f5c9d6c6667e0b 413 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 41 212 4.9E-54 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 STK_03770 99dbe5940e53fc6732f5c9d6c6667e0b 413 Gene3D G3DSA:3.40.720.10 7 398 1.8E-124 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 STK_03770 99dbe5940e53fc6732f5c9d6c6667e0b 413 Hamap MF_01402_A 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 4 404 43.744 T 23-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 STK_03770 99dbe5940e53fc6732f5c9d6c6667e0b 413 Pfam PF01676 Metalloenzyme superfamily 5 395 2.6E-38 T 23-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 STK_03770 99dbe5940e53fc6732f5c9d6c6667e0b 413 Gene3D G3DSA:3.30.70.2130 81 234 1.8E-124 T 23-10-2018 STK_03770 99dbe5940e53fc6732f5c9d6c6667e0b 413 PIRSF PIRSF006392 1 409 3.0E-148 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 STK_22260 032cfb553eb67d399da61771aa030f8b 203 Pfam PF01569 PAP2 superfamily 78 185 1.6E-20 T 23-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase STK_22260 032cfb553eb67d399da61771aa030f8b 203 SMART SM00014 76 185 1.9E-15 T 23-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase STK_22260 032cfb553eb67d399da61771aa030f8b 203 Gene3D G3DSA:1.20.144.10 108 195 2.3E-17 T 23-10-2018 STK_22260 032cfb553eb67d399da61771aa030f8b 203 SUPERFAMILY SSF48317 10 195 8.5E-48 T 23-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily STK_12910 203e78c39c7312dfba3b28a943e3c232 929 PIRSF PIRSF037307 1 929 1.5E-265 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 STK_12910 203e78c39c7312dfba3b28a943e3c232 929 SMART SM00490 257 339 4.4E-15 T 23-10-2018 IPR001650 Helicase, C-terminal STK_12910 203e78c39c7312dfba3b28a943e3c232 929 Pfam PF00271 Helicase conserved C-terminal domain 239 337 6.1E-14 T 23-10-2018 IPR001650 Helicase, C-terminal STK_12910 203e78c39c7312dfba3b28a943e3c232 929 SMART SM00487 16 222 4.6E-39 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain STK_12910 203e78c39c7312dfba3b28a943e3c232 929 Pfam PF00270 DEAD/DEAH box helicase 21 191 8.8E-30 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 STK_12910 203e78c39c7312dfba3b28a943e3c232 929 SUPERFAMILY SSF52540 30 354 9.34E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_12910 203e78c39c7312dfba3b28a943e3c232 929 Gene3D G3DSA:3.40.50.300 2 205 1.2E-45 T 23-10-2018 STK_12910 203e78c39c7312dfba3b28a943e3c232 929 Gene3D G3DSA:3.40.50.300 206 370 2.6E-22 T 23-10-2018 STK_12290 70704e24d0f2a7a91edc6fb0a792bc7a 433 Gene3D G3DSA:3.60.120.10 1 433 1.0E-155 T 23-10-2018 IPR005801 ADC synthase GO:0009058 STK_12290 70704e24d0f2a7a91edc6fb0a792bc7a 433 Pfam PF04715 Anthranilate synthase component I, N terminal region 11 142 5.7E-22 T 23-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 STK_12290 70704e24d0f2a7a91edc6fb0a792bc7a 433 SUPERFAMILY SSF56322 8 430 3.4E-140 T 23-10-2018 IPR005801 ADC synthase GO:0009058 STK_12290 70704e24d0f2a7a91edc6fb0a792bc7a 433 Pfam PF00425 chorismate binding enzyme 169 422 2.8E-92 T 23-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal STK_12290 70704e24d0f2a7a91edc6fb0a792bc7a 433 PRINTS PR00095 Anthranilate synthase component I signature 379 393 2.7E-21 T 23-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 STK_12290 70704e24d0f2a7a91edc6fb0a792bc7a 433 PRINTS PR00095 Anthranilate synthase component I signature 270 283 2.7E-21 T 23-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 STK_12290 70704e24d0f2a7a91edc6fb0a792bc7a 433 PRINTS PR00095 Anthranilate synthase component I signature 284 297 2.7E-21 T 23-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 STK_12290 70704e24d0f2a7a91edc6fb0a792bc7a 433 PRINTS PR00095 Anthranilate synthase component I signature 364 378 2.7E-21 T 23-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 STK_12290 70704e24d0f2a7a91edc6fb0a792bc7a 433 TIGRFAM TIGR01820 TrpE-arch: anthranilate synthase component I 12 431 1.3E-170 T 23-10-2018 IPR010116 Anthranilate synthase component I, archaeal type GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 STK_14320 42b9769dfef50a723abb319d4c5939bb 571 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 3 545 1.8E-159 T 23-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 STK_14320 42b9769dfef50a723abb319d4c5939bb 571 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 21 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_14320 42b9769dfef50a723abb319d4c5939bb 571 Gene3D G3DSA:2.20.28.20 139 173 2.2E-144 T 23-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 STK_14320 42b9769dfef50a723abb319d4c5939bb 571 Gene3D G3DSA:1.10.730.10 381 550 2.7E-43 T 23-10-2018 STK_14320 42b9769dfef50a723abb319d4c5939bb 571 Pfam PF09334 tRNA synthetases class I (M) 3 397 1.1E-151 T 23-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_14320 42b9769dfef50a723abb319d4c5939bb 571 PRINTS PR01041 Methionyl-tRNA synthetase signature 250 261 3.6E-18 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 STK_14320 42b9769dfef50a723abb319d4c5939bb 571 PRINTS PR01041 Methionyl-tRNA synthetase signature 290 305 3.6E-18 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 STK_14320 42b9769dfef50a723abb319d4c5939bb 571 PRINTS PR01041 Methionyl-tRNA synthetase signature 384 395 3.6E-18 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 STK_14320 42b9769dfef50a723abb319d4c5939bb 571 PRINTS PR01041 Methionyl-tRNA synthetase signature 5 18 3.6E-18 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 STK_14320 42b9769dfef50a723abb319d4c5939bb 571 PRINTS PR01041 Methionyl-tRNA synthetase signature 89 100 3.6E-18 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 STK_14320 42b9769dfef50a723abb319d4c5939bb 571 SUPERFAMILY SSF47323 385 544 4.3E-38 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_14320 42b9769dfef50a723abb319d4c5939bb 571 SUPERFAMILY SSF52374 2 384 9.19E-86 T 23-10-2018 STK_14320 42b9769dfef50a723abb319d4c5939bb 571 SUPERFAMILY SSF57770 139 173 9.68E-12 T 23-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 STK_14320 42b9769dfef50a723abb319d4c5939bb 571 Hamap MF_00098 Methionine--tRNA ligase [metG]. 1 557 38.9 T 23-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 STK_14320 42b9769dfef50a723abb319d4c5939bb 571 Gene3D G3DSA:3.40.50.620 3 380 2.2E-144 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_17380 f59be702d4160677c595d4c3e2731d83 379 Pfam PF01637 ATPase domain predominantly from Archaea 14 275 3.3E-15 T 23-10-2018 IPR011579 ATPase domain GO:0005524 STK_17380 f59be702d4160677c595d4c3e2731d83 379 Gene3D G3DSA:3.40.50.300 9 234 3.7E-36 T 23-10-2018 STK_17380 f59be702d4160677c595d4c3e2731d83 379 SUPERFAMILY SSF52540 3 306 1.52E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_17380 f59be702d4160677c595d4c3e2731d83 379 Gene3D G3DSA:1.10.8.60 235 313 6.5E-16 T 23-10-2018 STK_03800 85a7f874af1ed9aec0ec49de0c13de68 138 Pfam PF13638 PIN domain 11 122 1.2E-6 T 23-10-2018 IPR002716 PIN domain STK_03800 85a7f874af1ed9aec0ec49de0c13de68 138 SUPERFAMILY SSF88723 9 131 1.37E-23 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_03800 85a7f874af1ed9aec0ec49de0c13de68 138 Gene3D G3DSA:3.40.50.1010 8 136 2.5E-26 T 23-10-2018 STK_03800 85a7f874af1ed9aec0ec49de0c13de68 138 SMART SM00670 7 113 0.001 T 23-10-2018 IPR002716 PIN domain STK_17010 c5fdd5dcbab61ea9bd79ae12c2e11281 646 SUPERFAMILY SSF54862 538 632 5.02E-10 T 23-10-2018 STK_17010 c5fdd5dcbab61ea9bd79ae12c2e11281 646 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 614 625 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_17010 c5fdd5dcbab61ea9bd79ae12c2e11281 646 Gene3D G3DSA:3.30.70.20 565 642 6.1E-8 T 23-10-2018 STK_17010 c5fdd5dcbab61ea9bd79ae12c2e11281 646 Pfam PF00037 4Fe-4S binding domain 613 627 9.4E-5 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_19960 185f7d05a8311d613508caca714d529d 589 SMART SM00028 4 37 6.5E-4 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 STK_19960 185f7d05a8311d613508caca714d529d 589 SMART SM00220 295 586 9.3E-30 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 STK_19960 185f7d05a8311d613508caca714d529d 589 Pfam PF00069 Protein kinase domain 296 583 7.1E-37 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 STK_19960 185f7d05a8311d613508caca714d529d 589 Gene3D G3DSA:1.25.40.10 2 245 4.4E-16 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 STK_19960 185f7d05a8311d613508caca714d529d 589 Pfam PF07719 Tetratricopeptide repeat 6 37 3.1E-6 T 23-10-2018 IPR013105 Tetratricopeptide repeat 2 STK_19960 185f7d05a8311d613508caca714d529d 589 Gene3D G3DSA:1.10.510.10 288 588 1.2E-41 T 23-10-2018 STK_19960 185f7d05a8311d613508caca714d529d 589 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 301 323 - T 23-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 STK_19960 185f7d05a8311d613508caca714d529d 589 SUPERFAMILY SSF56112 270 583 3.51E-50 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily STK_19960 185f7d05a8311d613508caca714d529d 589 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 435 447 - T 23-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 STK_19960 185f7d05a8311d613508caca714d529d 589 SUPERFAMILY SSF48452 7 153 2.66E-13 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 STK_10460 9b1e758f53a80ec5e5fe469d9e1ccb60 142 PIRSF PIRSF004761 1 138 4.0E-38 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 STK_10460 9b1e758f53a80ec5e5fe469d9e1ccb60 142 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 133 2.8E-20 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 STK_10460 9b1e758f53a80ec5e5fe469d9e1ccb60 142 Gene3D G3DSA:3.30.2320.50 1 70 4.1E-10 T 23-10-2018 STK_10460 9b1e758f53a80ec5e5fe469d9e1ccb60 142 Gene3D G3DSA:2.20.28.10 71 124 4.0E-18 T 23-10-2018 STK_05290 80aceeac1d46a574f7bc0cf914341bc3 758 Gene3D G3DSA:3.30.465.40 6 140 1.1E-5 T 23-10-2018 STK_05290 80aceeac1d46a574f7bc0cf914341bc3 758 SUPERFAMILY SSF56176 79 131 1.03E-6 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 STK_05290 80aceeac1d46a574f7bc0cf914341bc3 758 Gene3D G3DSA:3.30.70.20 310 385 1.2E-5 T 23-10-2018 STK_05290 80aceeac1d46a574f7bc0cf914341bc3 758 Pfam PF01565 FAD binding domain 75 131 1.1E-5 T 23-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 STK_05290 80aceeac1d46a574f7bc0cf914341bc3 758 SUPERFAMILY SSF46548 312 379 5.23E-13 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 STK_05290 80aceeac1d46a574f7bc0cf914341bc3 758 Pfam PF13183 4Fe-4S dicluster domain 316 373 1.5E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_15140 8a36c6bd4ea00bf84cea78d27a10d768 351 SUPERFAMILY SSF102114 50 313 1.0E-34 T 23-10-2018 STK_15140 8a36c6bd4ea00bf84cea78d27a10d768 351 Gene3D G3DSA:3.20.20.70 56 284 1.2E-28 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_15140 8a36c6bd4ea00bf84cea78d27a10d768 351 Pfam PF04055 Radical SAM superfamily 79 232 2.2E-15 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_15140 8a36c6bd4ea00bf84cea78d27a10d768 351 PIRSF PIRSF004869 3 311 2.4E-88 T 23-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted STK_15140 8a36c6bd4ea00bf84cea78d27a10d768 351 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 10 348 9.1E-93 T 23-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme STK_10940 f2d2b8c4d64e0b4adc85758097554ced 282 SMART SM00478 135 272 5.8E-9 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 STK_10940 f2d2b8c4d64e0b4adc85758097554ced 282 Gene3D G3DSA:1.10.340.30 120 229 2.7E-18 T 23-10-2018 STK_10940 f2d2b8c4d64e0b4adc85758097554ced 282 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 130 253 5.1E-12 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 STK_10940 f2d2b8c4d64e0b4adc85758097554ced 282 SUPERFAMILY SSF48150 119 273 9.77E-29 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 STK_15690 e8beaf1796c238af76603200b9dc9347 266 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 3 80 3.9E-11 T 23-10-2018 IPR013589 Bacterial transglutaminase-like, N-terminal STK_15690 e8beaf1796c238af76603200b9dc9347 266 SUPERFAMILY SSF54001 9 247 4.14E-40 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily STK_15690 e8beaf1796c238af76603200b9dc9347 266 Pfam PF01841 Transglutaminase-like superfamily 116 217 6.3E-23 T 23-10-2018 IPR002931 Transglutaminase-like STK_15690 e8beaf1796c238af76603200b9dc9347 266 SMART SM00460 159 219 2.7E-14 T 23-10-2018 IPR002931 Transglutaminase-like STK_15690 e8beaf1796c238af76603200b9dc9347 266 Gene3D G3DSA:3.10.620.30 72 251 4.7E-47 T 23-10-2018 STK_23460 a4f91b8be05fe02af0bbbf6dcea9d8cf 325 Pfam PF01435 Peptidase family M48 83 321 1.6E-24 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 STK_23460 a4f91b8be05fe02af0bbbf6dcea9d8cf 325 Gene3D G3DSA:3.30.2010.10 73 162 1.1E-17 T 23-10-2018 STK_23460 a4f91b8be05fe02af0bbbf6dcea9d8cf 325 Hamap MF_00188 Protease HtpX [htpX]. 7 321 27.422 T 23-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 STK_02950 eb480e06c95e395266b3335b2971023b 404 SUPERFAMILY SSF53686 6 317 3.01E-95 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme STK_02950 eb480e06c95e395266b3335b2971023b 404 Gene3D G3DSA:3.40.50.1100 53 149 6.2E-115 T 23-10-2018 STK_02950 eb480e06c95e395266b3335b2971023b 404 Gene3D G3DSA:3.40.50.1100 12 310 6.2E-115 T 23-10-2018 STK_02950 eb480e06c95e395266b3335b2971023b 404 SUPERFAMILY SSF55021 329 393 6.87E-6 T 23-10-2018 STK_02950 eb480e06c95e395266b3335b2971023b 404 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 19 296 7.4E-81 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme STK_02950 eb480e06c95e395266b3335b2971023b 404 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 24 393 9.0E-141 T 23-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 STK_17340 48024b161923c7cdc17a1430864b2bdb 452 SUPERFAMILY SSF49464 59 101 1.88E-6 T 23-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily STK_17340 48024b161923c7cdc17a1430864b2bdb 452 Pfam PF12679 ABC-2 family transporter protein 258 451 6.1E-14 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 STK_21490 0269821919b551011f52d65a9dea714a 1000 SUPERFAMILY SSF46548 502 600 2.27E-13 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 STK_21490 0269821919b551011f52d65a9dea714a 1000 SUPERFAMILY SSF56176 36 209 5.14E-43 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 STK_21490 0269821919b551011f52d65a9dea714a 1000 Gene3D G3DSA:1.10.1060.10 507 603 1.5E-7 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 STK_21490 0269821919b551011f52d65a9dea714a 1000 Pfam PF13534 4Fe-4S dicluster domain 515 586 7.7E-9 T 23-10-2018 STK_21490 0269821919b551011f52d65a9dea714a 1000 SUPERFAMILY SSF55103 214 460 2.62E-10 T 23-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 STK_21490 0269821919b551011f52d65a9dea714a 1000 Pfam PF01565 FAD binding domain 46 182 1.5E-33 T 23-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 STK_21490 0269821919b551011f52d65a9dea714a 1000 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 572 583 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_21490 0269821919b551011f52d65a9dea714a 1000 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 516 527 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_21490 0269821919b551011f52d65a9dea714a 1000 Gene3D G3DSA:3.30.465.40 18 229 6.0E-42 T 23-10-2018 STK_19170 1cbecadc1ad97f42c4f6fdd3f0ab9b09 312 SMART SM00382 27 210 1.1E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_19170 1cbecadc1ad97f42c4f6fdd3f0ab9b09 312 SUPERFAMILY SSF52540 2 239 1.25E-84 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_19170 1cbecadc1ad97f42c4f6fdd3f0ab9b09 312 Pfam PF00005 ABC transporter 18 160 6.8E-37 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_19170 1cbecadc1ad97f42c4f6fdd3f0ab9b09 312 SUPERFAMILY SSF50331 242 305 9.86E-10 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal STK_19170 1cbecadc1ad97f42c4f6fdd3f0ab9b09 312 Pfam PF08402 TOBE domain 246 291 5.8E-5 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 STK_19170 1cbecadc1ad97f42c4f6fdd3f0ab9b09 312 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 STK_19170 1cbecadc1ad97f42c4f6fdd3f0ab9b09 312 Gene3D G3DSA:3.40.50.300 2 236 2.0E-76 T 23-10-2018 STK_02880 4efa9037fe1d9bc96daa3050b94c8765 450 PRINTS PR00149 Fumarate lyase superfamily signature 227 254 4.8E-25 T 23-10-2018 IPR000362 Fumarate lyase family STK_02880 4efa9037fe1d9bc96daa3050b94c8765 450 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 4.8E-25 T 23-10-2018 IPR000362 Fumarate lyase family STK_02880 4efa9037fe1d9bc96daa3050b94c8765 450 PRINTS PR00149 Fumarate lyase superfamily signature 272 288 4.8E-25 T 23-10-2018 IPR000362 Fumarate lyase family STK_02880 4efa9037fe1d9bc96daa3050b94c8765 450 PRINTS PR00149 Fumarate lyase superfamily signature 96 114 4.8E-25 T 23-10-2018 IPR000362 Fumarate lyase family STK_02880 4efa9037fe1d9bc96daa3050b94c8765 450 Gene3D G3DSA:1.10.275.10 3 100 2.2E-26 T 23-10-2018 IPR024083 Fumarase/histidase, N-terminal STK_02880 4efa9037fe1d9bc96daa3050b94c8765 450 Gene3D G3DSA:1.20.200.10 101 359 3.8E-89 T 23-10-2018 STK_02880 4efa9037fe1d9bc96daa3050b94c8765 450 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 8 437 5.8E-138 T 23-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 STK_02880 4efa9037fe1d9bc96daa3050b94c8765 450 PRINTS PR00145 Argininosuccinate lyase family signature 136 156 1.7E-11 T 23-10-2018 STK_02880 4efa9037fe1d9bc96daa3050b94c8765 450 PRINTS PR00145 Argininosuccinate lyase family signature 272 288 1.7E-11 T 23-10-2018 STK_02880 4efa9037fe1d9bc96daa3050b94c8765 450 PRINTS PR00145 Argininosuccinate lyase family signature 227 251 1.7E-11 T 23-10-2018 STK_02880 4efa9037fe1d9bc96daa3050b94c8765 450 Gene3D G3DSA:1.10.40.30 360 447 1.3E-16 T 23-10-2018 STK_02880 4efa9037fe1d9bc96daa3050b94c8765 450 SUPERFAMILY SSF48557 9 439 2.98E-119 T 23-10-2018 IPR008948 L-Aspartase-like GO:0003824 STK_02880 4efa9037fe1d9bc96daa3050b94c8765 450 SMART SM00998 360 440 1.5E-18 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 STK_02880 4efa9037fe1d9bc96daa3050b94c8765 450 Pfam PF00206 Lyase 40 294 9.9E-48 T 23-10-2018 IPR022761 Fumarate lyase, N-terminal STK_02880 4efa9037fe1d9bc96daa3050b94c8765 450 ProSitePatterns PS00163 Fumarate lyases signature. 272 281 - T 23-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 STK_02880 4efa9037fe1d9bc96daa3050b94c8765 450 Pfam PF10397 Adenylosuccinate lyase C-terminus 361 438 1.4E-11 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 STK_03310 5270f4c5cf0ce5ae1afc5e06cbb12ad8 165 SMART SM00530 83 138 2.1E-12 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 STK_03310 5270f4c5cf0ce5ae1afc5e06cbb12ad8 165 TIGRFAM TIGR00270 TIGR00270: TIGR00270 family protein 8 161 1.4E-29 T 23-10-2018 IPR004451 Conserved hypothetical protein CHP00270 STK_03310 5270f4c5cf0ce5ae1afc5e06cbb12ad8 165 SUPERFAMILY SSF47413 81 139 4.29E-14 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 STK_03310 5270f4c5cf0ce5ae1afc5e06cbb12ad8 165 Pfam PF01381 Helix-turn-helix 84 135 3.3E-12 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 STK_03310 5270f4c5cf0ce5ae1afc5e06cbb12ad8 165 Gene3D G3DSA:1.10.260.40 70 165 8.4E-23 T 23-10-2018 STK_17890 b45089bd469eb474a533d407ce6da42b 391 Pfam PF04976 DMSO reductase anchor subunit (DmsC) 207 307 1.9E-12 T 23-10-2018 IPR007059 DMSO reductase anchor subunit (DmsC) GO:0016021|GO:0019645 STK_17890 b45089bd469eb474a533d407ce6da42b 391 Pfam PF13247 4Fe-4S dicluster domain 49 138 7.8E-21 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_17890 b45089bd469eb474a533d407ce6da42b 391 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_17890 b45089bd469eb474a533d407ce6da42b 391 SUPERFAMILY SSF54862 4 166 1.03E-48 T 23-10-2018 STK_17890 b45089bd469eb474a533d407ce6da42b 391 Gene3D G3DSA:3.30.70.20 38 173 5.7E-38 T 23-10-2018 STK_02120 64019efaccae10d8ba250fae872cab44 412 SUPERFAMILY SSF69742 10 157 9.55E-32 T 23-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 STK_02120 64019efaccae10d8ba250fae872cab44 412 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 396 19.467 T 23-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 STK_02120 64019efaccae10d8ba250fae872cab44 412 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 174 268 6.9E-15 T 23-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase STK_02120 64019efaccae10d8ba250fae872cab44 412 SUPERFAMILY SSF51735 160 271 1.67E-17 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_02120 64019efaccae10d8ba250fae872cab44 412 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 98 121 - T 23-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 STK_02120 64019efaccae10d8ba250fae872cab44 412 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 17 155 4.9E-31 T 23-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 STK_02120 64019efaccae10d8ba250fae872cab44 412 SUPERFAMILY SSF69075 297 398 5.23E-16 T 23-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 STK_02120 64019efaccae10d8ba250fae872cab44 412 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 299 394 3.9E-11 T 23-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 STK_02120 64019efaccae10d8ba250fae872cab44 412 Gene3D G3DSA:3.40.50.720 158 298 3.4E-21 T 23-10-2018 STK_02120 64019efaccae10d8ba250fae872cab44 412 Gene3D G3DSA:3.30.460.30 13 157 6.1E-33 T 23-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 STK_02120 64019efaccae10d8ba250fae872cab44 412 PIRSF PIRSF000445 9 412 1.2E-87 T 23-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 STK_14910 e62c8384fbad385241a38c70a482120f 334 Gene3D G3DSA:3.40.50.300 150 328 4.5E-44 T 23-10-2018 STK_14910 e62c8384fbad385241a38c70a482120f 334 Gene3D G3DSA:1.20.120.1190 1 149 1.8E-26 T 23-10-2018 STK_14910 e62c8384fbad385241a38c70a482120f 334 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 207 222 8.8E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 STK_14910 e62c8384fbad385241a38c70a482120f 334 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 180 198 8.8E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 STK_14910 e62c8384fbad385241a38c70a482120f 334 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 159 179 8.8E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 STK_14910 e62c8384fbad385241a38c70a482120f 334 Pfam PF01926 50S ribosome-binding GTPase 159 276 1.9E-19 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 STK_14910 e62c8384fbad385241a38c70a482120f 334 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 158 314 2.0E-17 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 STK_14910 e62c8384fbad385241a38c70a482120f 334 SUPERFAMILY SSF52540 149 324 1.15E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_00700 ee21ddd736bc9bd20436d58e7bcd170d 253 Pfam PF00106 short chain dehydrogenase 7 193 4.4E-50 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_00700 ee21ddd736bc9bd20436d58e7bcd170d 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.5E-33 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_00700 ee21ddd736bc9bd20436d58e7bcd170d 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.5E-33 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_00700 ee21ddd736bc9bd20436d58e7bcd170d 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.5E-33 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_00700 ee21ddd736bc9bd20436d58e7bcd170d 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.5E-33 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_00700 ee21ddd736bc9bd20436d58e7bcd170d 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 2.5E-33 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_00700 ee21ddd736bc9bd20436d58e7bcd170d 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.5E-33 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_00700 ee21ddd736bc9bd20436d58e7bcd170d 253 Gene3D G3DSA:3.40.50.720 1 249 2.9E-64 T 23-10-2018 STK_00700 ee21ddd736bc9bd20436d58e7bcd170d 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.3E-12 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_00700 ee21ddd736bc9bd20436d58e7bcd170d 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 3.3E-12 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_00700 ee21ddd736bc9bd20436d58e7bcd170d 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.3E-12 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_00700 ee21ddd736bc9bd20436d58e7bcd170d 253 SUPERFAMILY SSF51735 5 247 4.26E-66 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_22150 49908ac2b44379aca933db864f30175d 257 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 1 207 30.858 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 STK_22150 49908ac2b44379aca933db864f30175d 257 Pfam PF02511 Thymidylate synthase complementing protein 4 193 6.2E-64 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 STK_22150 49908ac2b44379aca933db864f30175d 257 SUPERFAMILY SSF69796 1 205 2.35E-60 T 23-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 STK_22150 49908ac2b44379aca933db864f30175d 257 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 3 198 1.7E-62 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 STK_22150 49908ac2b44379aca933db864f30175d 257 Gene3D G3DSA:3.30.1360.170 1 205 3.2E-65 T 23-10-2018 STK_13120 602b110a2e1254bcb51cdb808e64e8fa 619 Gene3D G3DSA:1.10.8.730 354 458 3.4E-69 T 23-10-2018 STK_13120 602b110a2e1254bcb51cdb808e64e8fa 619 SUPERFAMILY SSF52540 267 598 6.12E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_13120 602b110a2e1254bcb51cdb808e64e8fa 619 Pfam PF01935 Domain of unknown function DUF87 287 412 3.5E-9 T 23-10-2018 IPR002789 Helicase HerA, central domain STK_13120 602b110a2e1254bcb51cdb808e64e8fa 619 Pfam PF12846 AAA-like domain 483 547 8.6E-8 T 23-10-2018 STK_13120 602b110a2e1254bcb51cdb808e64e8fa 619 Gene3D G3DSA:3.40.50.300 290 603 3.4E-69 T 23-10-2018 STK_02300 aaf7fc12d36852dc3661dfcc08e9feeb 154 Gene3D G3DSA:3.40.50.1010 3 80 1.6E-5 T 23-10-2018 STK_02300 aaf7fc12d36852dc3661dfcc08e9feeb 154 Pfam PF01927 Mut7-C RNAse domain 4 135 2.1E-35 T 23-10-2018 IPR002782 Mut7-C RNAse domain STK_02300 aaf7fc12d36852dc3661dfcc08e9feeb 154 SUPERFAMILY SSF88723 7 72 1.26E-6 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_10130 fbd90c8fd44f5bc50392f3b36fe3c43d 637 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 106 587 1.5E-86 T 23-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 STK_10130 fbd90c8fd44f5bc50392f3b36fe3c43d 637 Gene3D G3DSA:3.30.365.20 490 637 1.6E-22 T 23-10-2018 STK_10130 fbd90c8fd44f5bc50392f3b36fe3c43d 637 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 5 99 3.8E-6 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead STK_10130 fbd90c8fd44f5bc50392f3b36fe3c43d 637 Gene3D G3DSA:3.30.365.10 136 228 1.5E-51 T 23-10-2018 STK_10130 fbd90c8fd44f5bc50392f3b36fe3c43d 637 Gene3D G3DSA:3.30.365.10 345 378 8.8E-20 T 23-10-2018 STK_10130 fbd90c8fd44f5bc50392f3b36fe3c43d 637 SUPERFAMILY SSF56003 125 633 4.06E-104 T 23-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 STK_10130 fbd90c8fd44f5bc50392f3b36fe3c43d 637 SMART SM01008 5 100 2.1E-5 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead STK_10130 fbd90c8fd44f5bc50392f3b36fe3c43d 637 Gene3D G3DSA:3.90.1170.50 3 100 9.1E-12 T 23-10-2018 STK_10130 fbd90c8fd44f5bc50392f3b36fe3c43d 637 Gene3D G3DSA:3.30.365.10 379 481 8.8E-20 T 23-10-2018 STK_10130 fbd90c8fd44f5bc50392f3b36fe3c43d 637 Gene3D G3DSA:3.30.365.10 128 339 1.5E-51 T 23-10-2018 STK_10130 fbd90c8fd44f5bc50392f3b36fe3c43d 637 SUPERFAMILY SSF54665 5 100 3.4E-13 T 23-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily STK_15010 06c195226848897f20f547014b90e66e 390 Gene3D G3DSA:3.40.50.620 3 164 9.2E-138 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_15010 06c195226848897f20f547014b90e66e 390 Gene3D G3DSA:3.90.1260.10 61 346 9.2E-138 T 23-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 STK_15010 06c195226848897f20f547014b90e66e 390 Hamap MF_00005 Argininosuccinate synthase [argG]. 1 390 45.312 T 23-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 STK_15010 06c195226848897f20f547014b90e66e 390 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 6 14 - T 23-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 STK_15010 06c195226848897f20f547014b90e66e 390 SUPERFAMILY SSF52402 1 162 2.92E-46 T 23-10-2018 STK_15010 06c195226848897f20f547014b90e66e 390 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 114 125 - T 23-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 STK_15010 06c195226848897f20f547014b90e66e 390 Pfam PF00764 Arginosuccinate synthase 4 382 1.5E-140 T 23-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 STK_15010 06c195226848897f20f547014b90e66e 390 SUPERFAMILY SSF69864 168 388 1.06E-74 T 23-10-2018 STK_15010 06c195226848897f20f547014b90e66e 390 TIGRFAM TIGR00032 argG: argininosuccinate synthase 2 387 3.9E-136 T 23-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 STK_01630 aa43e05413e3864cc0f6596a77ddf02b 104 Pfam PF13187 4Fe-4S dicluster domain 46 99 5.4E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_01630 aa43e05413e3864cc0f6596a77ddf02b 104 Gene3D G3DSA:3.30.70.20 2 104 4.3E-44 T 23-10-2018 STK_01630 aa43e05413e3864cc0f6596a77ddf02b 104 SUPERFAMILY SSF54862 23 102 8.97E-20 T 23-10-2018 STK_01630 aa43e05413e3864cc0f6596a77ddf02b 104 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 84 95 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_01630 aa43e05413e3864cc0f6596a77ddf02b 104 PIRSF PIRSF000068 1 104 5.0E-43 T 23-10-2018 IPR009157 Ferredoxin zinc-binding GO:0008270|GO:0009055|GO:0051536 STK_01250 a88fbd7351b66f218c94c7906fd62f14 154 SUPERFAMILY SSF118196 2 147 2.35E-37 T 23-10-2018 IPR036413 YaeB-like superfamily STK_01250 a88fbd7351b66f218c94c7906fd62f14 154 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 12 124 1.6E-30 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain STK_01250 a88fbd7351b66f218c94c7906fd62f14 154 Gene3D G3DSA:2.40.30.70 3 144 3.8E-33 T 23-10-2018 IPR036414 YaeB, N-terminal domain superfamily STK_01250 a88fbd7351b66f218c94c7906fd62f14 154 Pfam PF01980 Uncharacterised protein family UPF0066 12 124 1.6E-30 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain STK_08360 c21e852a541bd42bbfc24bf2eefc3289 311 Pfam PF01435 Peptidase family M48 74 303 9.9E-33 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 STK_08360 c21e852a541bd42bbfc24bf2eefc3289 311 Gene3D G3DSA:3.30.2010.10 63 153 1.7E-21 T 23-10-2018 STK_08360 c21e852a541bd42bbfc24bf2eefc3289 311 Hamap MF_00188 Protease HtpX [htpX]. 6 305 25.438 T 23-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 STK_25470 912b2c7f99acc017f7b6b9e7f9bee3df 413 Gene3D G3DSA:3.30.465.40 20 231 3.4E-29 T 23-10-2018 STK_25470 912b2c7f99acc017f7b6b9e7f9bee3df 413 Pfam PF02913 FAD linked oxidases, C-terminal domain 387 411 1.2E-4 T 23-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 STK_25470 912b2c7f99acc017f7b6b9e7f9bee3df 413 SUPERFAMILY SSF55103 355 412 6.05E-7 T 23-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 STK_25470 912b2c7f99acc017f7b6b9e7f9bee3df 413 Pfam PF01565 FAD binding domain 49 182 7.9E-27 T 23-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 STK_25470 912b2c7f99acc017f7b6b9e7f9bee3df 413 Gene3D G3DSA:1.10.45.10 382 411 5.1E-7 T 23-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 STK_25470 912b2c7f99acc017f7b6b9e7f9bee3df 413 SUPERFAMILY SSF56176 28 211 2.43E-31 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 STK_26180 cab12ac7d1d703adff4dece12f54ecf3 445 SUPERFAMILY SSF103473 11 425 7.85E-56 T 23-10-2018 IPR036259 MFS transporter superfamily STK_26180 cab12ac7d1d703adff4dece12f54ecf3 445 ProSitePatterns PS00217 Sugar transport proteins signature 2. 123 148 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 STK_26180 cab12ac7d1d703adff4dece12f54ecf3 445 Pfam PF07690 Major Facilitator Superfamily 18 377 2.7E-25 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_26180 cab12ac7d1d703adff4dece12f54ecf3 445 Gene3D G3DSA:1.20.1250.20 10 444 5.1E-55 T 23-10-2018 STK_15650 fc7d86d25b5d9d0d6b3a4bac4148e566 429 Gene3D G3DSA:1.10.510.10 132 425 8.7E-33 T 23-10-2018 STK_15650 fc7d86d25b5d9d0d6b3a4bac4148e566 429 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 283 295 - T 23-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 STK_15650 fc7d86d25b5d9d0d6b3a4bac4148e566 429 SUPERFAMILY SSF56112 127 422 1.11E-39 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily STK_15650 fc7d86d25b5d9d0d6b3a4bac4148e566 429 Pfam PF00069 Protein kinase domain 139 421 1.3E-25 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 STK_15650 fc7d86d25b5d9d0d6b3a4bac4148e566 429 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 145 166 - T 23-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 STK_15650 fc7d86d25b5d9d0d6b3a4bac4148e566 429 SMART SM00220 139 428 9.0E-13 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 STK_10910 e39295f805b0b261e2292ccec329c0f4 441 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 249 328 2.4E-18 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_06110 1c38f4accb4f9df687ab8b0153c9d5ce 569 Gene3D G3DSA:1.20.210.10 35 546 2.2E-74 T 23-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_06110 1c38f4accb4f9df687ab8b0153c9d5ce 569 PRINTS PR01165 Cytochrome c oxidase subunit I signature 165 177 8.2E-7 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_06110 1c38f4accb4f9df687ab8b0153c9d5ce 569 PRINTS PR01165 Cytochrome c oxidase subunit I signature 453 474 8.2E-7 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_06110 1c38f4accb4f9df687ab8b0153c9d5ce 569 PRINTS PR01165 Cytochrome c oxidase subunit I signature 90 113 8.2E-7 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_06110 1c38f4accb4f9df687ab8b0153c9d5ce 569 PRINTS PR01165 Cytochrome c oxidase subunit I signature 402 421 8.2E-7 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_06110 1c38f4accb4f9df687ab8b0153c9d5ce 569 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 49 497 1.3E-66 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_06110 1c38f4accb4f9df687ab8b0153c9d5ce 569 SUPERFAMILY SSF81442 49 522 9.94E-87 T 23-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_18895 1f77664a6e77974582614f8a45589996 85 SUPERFAMILY SSF64307 1 71 4.84E-16 T 23-10-2018 IPR036868 TusA-like domain superfamily STK_18895 1f77664a6e77974582614f8a45589996 85 Gene3D G3DSA:3.30.110.40 1 70 1.2E-8 T 23-10-2018 IPR036868 TusA-like domain superfamily STK_18895 1f77664a6e77974582614f8a45589996 85 Pfam PF01206 Sulfurtransferase TusA 3 70 5.2E-13 T 23-10-2018 IPR001455 TusA-like domain STK_03610 5bdd0c2b992b192ff5fd4137516c5a4c 266 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 183 2.7E-6 T 23-10-2018 STK_03610 5bdd0c2b992b192ff5fd4137516c5a4c 266 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 35 57 2.7E-6 T 23-10-2018 STK_03610 5bdd0c2b992b192ff5fd4137516c5a4c 266 Gene3D G3DSA:3.50.50.60 8 266 7.1E-96 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_03610 5bdd0c2b992b192ff5fd4137516c5a4c 266 Hamap MF_00304 Thiamine thiazole synthase [thi4]. 11 264 43.171 T 23-10-2018 IPR022828 Thiazole biosynthetic enzyme, prokaryotic STK_03610 5bdd0c2b992b192ff5fd4137516c5a4c 266 TIGRFAM TIGR00292 TIGR00292: thiazole biosynthesis enzyme 13 263 3.0E-105 T 23-10-2018 IPR002922 Thiazole biosynthetic enzyme Thi4 family STK_03610 5bdd0c2b992b192ff5fd4137516c5a4c 266 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 36 55 5.6E-8 T 23-10-2018 STK_03610 5bdd0c2b992b192ff5fd4137516c5a4c 266 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 5.6E-8 T 23-10-2018 STK_03610 5bdd0c2b992b192ff5fd4137516c5a4c 266 SUPERFAMILY SSF51905 6 262 1.48E-47 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_03610 5bdd0c2b992b192ff5fd4137516c5a4c 266 Pfam PF01946 Thi4 family 17 245 9.5E-82 T 23-10-2018 STK_04180 d7d540e2dcd123c67b9336eb35f560be 186 PIRSF PIRSF002162 2 180 5.9E-35 T 23-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04180 d7d540e2dcd123c67b9336eb35f560be 186 Gene3D G3DSA:3.90.930.12 86 182 1.4E-33 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04180 d7d540e2dcd123c67b9336eb35f560be 186 SUPERFAMILY SSF56053 3 85 1.2E-20 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04180 d7d540e2dcd123c67b9336eb35f560be 186 ProSitePatterns PS00700 Ribosomal protein L6 signature 2. 156 177 - T 23-10-2018 IPR002359 Ribosomal protein L6, conserved site-2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04180 d7d540e2dcd123c67b9336eb35f560be 186 Gene3D G3DSA:3.90.930.12 7 85 8.9E-25 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04180 d7d540e2dcd123c67b9336eb35f560be 186 TIGRFAM TIGR03653 uL6_arch: ribosomal protein uL6 8 177 2.2E-72 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 STK_04180 d7d540e2dcd123c67b9336eb35f560be 186 Hamap MF_01365_A 50S ribosomal protein L6 [rplF]. 1 178 36.638 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 STK_04180 d7d540e2dcd123c67b9336eb35f560be 186 Pfam PF00347 Ribosomal protein L6 97 171 1.1E-12 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04180 d7d540e2dcd123c67b9336eb35f560be 186 Pfam PF00347 Ribosomal protein L6 12 85 3.3E-16 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04180 d7d540e2dcd123c67b9336eb35f560be 186 SUPERFAMILY SSF56053 86 177 1.5E-26 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_01420 1523d976c0f8a5d899120c351bf0931e 242 Pfam PF13384 Homeodomain-like domain 52 90 9.5E-8 T 23-10-2018 STK_01420 1523d976c0f8a5d899120c351bf0931e 242 Gene3D G3DSA:1.10.10.10 48 96 3.7E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_01420 1523d976c0f8a5d899120c351bf0931e 242 SUPERFAMILY SSF46689 49 130 2.78E-10 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 STK_25060 c62fbf8f9f5f8c4a7cbe68234435ea3b 218 Gene3D G3DSA:3.40.190.200 1 191 2.3E-26 T 23-10-2018 STK_25060 c62fbf8f9f5f8c4a7cbe68234435ea3b 218 Pfam PF12916 Protein of unknown function (DUF3834) 3 195 4.4E-74 T 23-10-2018 IPR024533 Protein of unknown function DUF3834 STK_25060 c62fbf8f9f5f8c4a7cbe68234435ea3b 218 SUPERFAMILY SSF53850 58 196 3.31E-9 T 23-10-2018 STK_04605 694cf2d822484d1da3bbd4f6ac05286d 89 Gene3D G3DSA:1.20.1440.50 6 89 6.2E-33 T 23-10-2018 IPR023130 Ta0600-like superfamily STK_04605 694cf2d822484d1da3bbd4f6ac05286d 89 ProDom PD029943 UPF0147 ARCHAEAL PF0239 ST0460.1 MM1385 CYTOSOLIC SACI_0891 TV0625 APES069 TA0600 11 88 2.0E-38 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 STK_04605 694cf2d822484d1da3bbd4f6ac05286d 89 Hamap MF_00342 UPF0147 protein . 7 88 31.483 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 STK_04605 694cf2d822484d1da3bbd4f6ac05286d 89 Pfam PF03685 Uncharacterised protein family (UPF0147) 7 87 1.5E-36 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 STK_04605 694cf2d822484d1da3bbd4f6ac05286d 89 SUPERFAMILY SSF158436 4 89 5.23E-35 T 23-10-2018 STK_25640 303e2539a424c0f2097192549e0cda17 293 Pfam PF00581 Rhodanese-like domain 13 122 9.8E-17 T 23-10-2018 IPR001763 Rhodanese-like domain STK_25640 303e2539a424c0f2097192549e0cda17 293 Pfam PF00581 Rhodanese-like domain 168 280 2.6E-20 T 23-10-2018 IPR001763 Rhodanese-like domain STK_25640 303e2539a424c0f2097192549e0cda17 293 Gene3D G3DSA:3.40.250.10 4 147 2.6E-38 T 23-10-2018 IPR036873 Rhodanese-like domain superfamily STK_25640 303e2539a424c0f2097192549e0cda17 293 ProSitePatterns PS00683 Rhodanese C-terminal signature. 269 279 - T 23-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 STK_25640 303e2539a424c0f2097192549e0cda17 293 SUPERFAMILY SSF52821 6 135 5.24E-35 T 23-10-2018 IPR036873 Rhodanese-like domain superfamily STK_25640 303e2539a424c0f2097192549e0cda17 293 Gene3D G3DSA:3.40.250.10 152 292 7.9E-41 T 23-10-2018 IPR036873 Rhodanese-like domain superfamily STK_25640 303e2539a424c0f2097192549e0cda17 293 SMART SM00450 11 126 7.8E-19 T 23-10-2018 IPR001763 Rhodanese-like domain STK_25640 303e2539a424c0f2097192549e0cda17 293 SMART SM00450 157 285 4.4E-24 T 23-10-2018 IPR001763 Rhodanese-like domain STK_25640 303e2539a424c0f2097192549e0cda17 293 SUPERFAMILY SSF52821 157 290 1.57E-36 T 23-10-2018 IPR036873 Rhodanese-like domain superfamily STK_09800 59a19a999e75f2efa553bae1787a233a 107 SUPERFAMILY SSF46785 5 92 6.3E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_09800 59a19a999e75f2efa553bae1787a233a 107 Gene3D G3DSA:1.10.10.10 1 107 5.1E-42 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_09800 59a19a999e75f2efa553bae1787a233a 107 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 15 82 1.6E-11 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal STK_11020 530eab625ddd2d4e04f206707a6ff920 899 Gene3D G3DSA:3.20.110.20 386 678 1.7E-29 T 23-10-2018 STK_11020 530eab625ddd2d4e04f206707a6ff920 899 SUPERFAMILY SSF88713 342 671 9.78E-76 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 STK_11020 530eab625ddd2d4e04f206707a6ff920 899 PIRSF PIRSF032656 1 899 0.0 T 23-10-2018 IPR017002 Glycoside hydrolase, family 57, Saci1162, predicted STK_11020 530eab625ddd2d4e04f206707a6ff920 899 Pfam PF03065 Glycosyl hydrolase family 57 347 658 3.2E-48 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 STK_20680 4f306057353fb9417e94b9daae683f23 132 PIRSF PIRSF002131 1 131 1.1E-31 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 STK_20680 4f306057353fb9417e94b9daae683f23 132 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 23-10-2018 IPR018102 Ribosomal S11, conserved site STK_20680 4f306057353fb9417e94b9daae683f23 132 Gene3D G3DSA:3.30.420.80 1 132 2.2E-57 T 23-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 STK_20680 4f306057353fb9417e94b9daae683f23 132 TIGRFAM TIGR03628 arch_S11P: ribosomal protein uS11 8 124 5.4E-61 T 23-10-2018 IPR019961 Ribosomal protein S11, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_20680 4f306057353fb9417e94b9daae683f23 132 Pfam PF00411 Ribosomal protein S11 10 128 7.8E-49 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 STK_20680 4f306057353fb9417e94b9daae683f23 132 SUPERFAMILY SSF53137 5 130 3.66E-34 T 23-10-2018 STK_20680 4f306057353fb9417e94b9daae683f23 132 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 4 129 21.733 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 STK_19790 21f876b5b093e2580c1281b8dbfc6977 998 Gene3D G3DSA:3.30.70.2230 726 872 4.7E-15 T 23-10-2018 STK_19790 21f876b5b093e2580c1281b8dbfc6977 998 Gene3D G3DSA:3.30.70.2220 192 319 2.0E-29 T 23-10-2018 IPR038242 Cmr2, N-terminal domain superfamily STK_19790 21f876b5b093e2580c1281b8dbfc6977 998 TIGRFAM TIGR02577 cas_TM1794_Cmr2: CRISPR-associated protein Cas10/Cmr2, subtype III-B 223 850 3.3E-186 T 23-10-2018 IPR013407 CRISPR-associated protein Cmr2 STK_19790 21f876b5b093e2580c1281b8dbfc6977 998 Pfam PF12469 CRISPR-associated protein 223 372 3.5E-24 T 23-10-2018 IPR024615 CRISPR-associated protein Cmr2, N-terminal STK_02070 225d75918a91a1158759a1e7a4113afe 363 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 20 272 6.2E-55 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 STK_02070 225d75918a91a1158759a1e7a4113afe 363 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 288 354 1.3E-6 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 STK_02070 225d75918a91a1158759a1e7a4113afe 363 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 4 359 21.942 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 STK_02070 225d75918a91a1158759a1e7a4113afe 363 SUPERFAMILY SSF55120 5 357 1.58E-49 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 STK_02070 225d75918a91a1158759a1e7a4113afe 363 Gene3D G3DSA:1.10.1510.30 164 250 2.7E-17 T 23-10-2018 STK_02070 225d75918a91a1158759a1e7a4113afe 363 Gene3D G3DSA:3.30.2350.20 278 360 1.3E-6 T 23-10-2018 STK_02070 225d75918a91a1158759a1e7a4113afe 363 Gene3D G3DSA:3.30.70.3160 41 123 1.6E-8 T 23-10-2018 STK_02590 d6fd313b668348fede7593be3141b93c 138 Gene3D G3DSA:3.60.21.10 27 137 9.6E-9 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like STK_02590 d6fd313b668348fede7593be3141b93c 138 SUPERFAMILY SSF56300 2 134 7.34E-22 T 23-10-2018 STK_13045 38d70a62e766fdb594533e7e4dc4005e 78 SUPERFAMILY SSF46785 14 60 4.63E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_13045 38d70a62e766fdb594533e7e4dc4005e 78 Pfam PF05584 Sulfolobus plasmid regulatory protein 6 77 4.6E-44 T 23-10-2018 IPR008848 Plasmid regulator, Sulfolobaceae STK_13045 38d70a62e766fdb594533e7e4dc4005e 78 Gene3D G3DSA:1.10.10.10 3 78 2.6E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_00165 b9a9e45cc42023046206c47ce9f14b69 77 SMART SM00966 5 48 1.6E-10 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_00165 b9a9e45cc42023046206c47ce9f14b69 77 Gene3D G3DSA:2.10.260.10 1 46 1.2E-12 T 23-10-2018 STK_00165 b9a9e45cc42023046206c47ce9f14b69 77 SUPERFAMILY SSF89447 3 54 1.36E-13 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily STK_00165 b9a9e45cc42023046206c47ce9f14b69 77 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 4 45 1.8E-15 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_00165 b9a9e45cc42023046206c47ce9f14b69 77 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 6 48 1.5E-11 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_13260 18877025b64e4f1725a1d0cf23622aa8 1016 SUPERFAMILY SSF52540 207 602 8.62E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_13260 18877025b64e4f1725a1d0cf23622aa8 1016 Gene3D G3DSA:3.40.50.300 206 360 5.1E-14 T 23-10-2018 STK_13260 18877025b64e4f1725a1d0cf23622aa8 1016 Gene3D G3DSA:3.40.50.300 406 597 1.8E-15 T 23-10-2018 STK_13260 18877025b64e4f1725a1d0cf23622aa8 1016 Pfam PF10412 Type IV secretion-system coupling protein DNA-binding domain 235 527 3.6E-9 T 23-10-2018 IPR019476 Type IV secretion system coupling protein TraD, DNA-binding domain STK_02830 06c342bf80b0b6b95053d3d65cab4d43 235 Gene3D G3DSA:3.40.50.2020 58 233 4.2E-34 T 23-10-2018 STK_02830 06c342bf80b0b6b95053d3d65cab4d43 235 Pfam PF00156 Phosphoribosyl transferase domain 93 222 4.6E-13 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 STK_02830 06c342bf80b0b6b95053d3d65cab4d43 235 SUPERFAMILY SSF53271 82 216 2.96E-28 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like STK_17430 f0337be9eb59b0fcabc4d784c5a59db2 322 Gene3D G3DSA:1.10.196.30 12 54 8.9E-29 T 23-10-2018 STK_17430 f0337be9eb59b0fcabc4d784c5a59db2 322 TIGRFAM TIGR02619 TIGR02619: putative CRISPR-associated protein, APE2256 family 61 201 5.6E-19 T 23-10-2018 IPR013442 CRISPR-associated protein APE2256 STK_17430 f0337be9eb59b0fcabc4d784c5a59db2 322 Pfam PF09651 CRISPR-associated protein (Cas_APE2256) 68 202 1.1E-36 T 23-10-2018 IPR013442 CRISPR-associated protein APE2256 STK_17430 f0337be9eb59b0fcabc4d784c5a59db2 322 Gene3D G3DSA:1.10.10.1690 209 269 6.7E-41 T 23-10-2018 STK_17430 f0337be9eb59b0fcabc4d784c5a59db2 322 Gene3D G3DSA:3.40.50.10770 55 208 2.8E-53 T 23-10-2018 STK_17430 f0337be9eb59b0fcabc4d784c5a59db2 322 PIRSF PIRSF014470 1 322 2.4E-185 T 23-10-2018 IPR016620 Uncharacterised conserved protein UCP014470 STK_02170 6ae28dc80deae71c92310165d5f8d896 294 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 3 204 1.2E-57 T 23-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 STK_02170 6ae28dc80deae71c92310165d5f8d896 294 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 2 290 32.14 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 STK_02170 6ae28dc80deae71c92310165d5f8d896 294 PRINTS PR00151 Porphobilinogen deaminase signature 221 238 3.2E-22 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 STK_02170 6ae28dc80deae71c92310165d5f8d896 294 PRINTS PR00151 Porphobilinogen deaminase signature 116 133 3.2E-22 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 STK_02170 6ae28dc80deae71c92310165d5f8d896 294 PRINTS PR00151 Porphobilinogen deaminase signature 135 152 3.2E-22 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 STK_02170 6ae28dc80deae71c92310165d5f8d896 294 PRINTS PR00151 Porphobilinogen deaminase signature 70 89 3.2E-22 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 STK_02170 6ae28dc80deae71c92310165d5f8d896 294 Gene3D G3DSA:3.30.160.40 213 292 4.9E-6 T 23-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 STK_02170 6ae28dc80deae71c92310165d5f8d896 294 SUPERFAMILY SSF54782 211 290 9.94E-12 T 23-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 STK_02170 6ae28dc80deae71c92310165d5f8d896 294 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 222 238 - T 23-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 STK_02170 6ae28dc80deae71c92310165d5f8d896 294 Gene3D G3DSA:3.40.190.10 3 206 1.0E-54 T 23-10-2018 STK_02170 6ae28dc80deae71c92310165d5f8d896 294 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 3 280 2.3E-95 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 STK_02170 6ae28dc80deae71c92310165d5f8d896 294 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 219 288 2.8E-6 T 23-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 STK_02170 6ae28dc80deae71c92310165d5f8d896 294 PIRSF PIRSF001438 1 293 4.6E-82 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 STK_02170 6ae28dc80deae71c92310165d5f8d896 294 Gene3D G3DSA:3.40.190.10 94 190 1.0E-54 T 23-10-2018 STK_02170 6ae28dc80deae71c92310165d5f8d896 294 SUPERFAMILY SSF53850 1 209 3.91E-59 T 23-10-2018 STK_13720 c37d45ed5bf04db1b87fdbbccff5174c 223 Gene3D G3DSA:3.75.10.10 1 222 3.1E-70 T 23-10-2018 STK_13720 c37d45ed5bf04db1b87fdbbccff5174c 223 Pfam PF01912 eIF-6 family 5 203 2.2E-65 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 STK_13720 c37d45ed5bf04db1b87fdbbccff5174c 223 Hamap MF_00032 Translation initiation factor 6 [eif6]. 1 223 83.108 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 STK_13720 c37d45ed5bf04db1b87fdbbccff5174c 223 SUPERFAMILY SSF55909 3 222 2.65E-69 T 23-10-2018 STK_13720 c37d45ed5bf04db1b87fdbbccff5174c 223 PIRSF PIRSF006413 2 223 5.3E-82 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 STK_13720 c37d45ed5bf04db1b87fdbbccff5174c 223 SMART SM00654 4 203 2.7E-93 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 STK_13720 c37d45ed5bf04db1b87fdbbccff5174c 223 TIGRFAM TIGR00323 eIF-6: putative translation initiation factor eIF-6 8 221 1.8E-54 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 STK_11180 9187fc775173d35f414ab64d818f82c2 464 SUPERFAMILY SSF51338 364 458 3.24E-35 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_11180 9187fc775173d35f414ab64d818f82c2 464 Gene3D G3DSA:2.30.40.10 5 459 5.7E-167 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_11180 9187fc775173d35f414ab64d818f82c2 464 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 6 456 1.7E-153 T 23-10-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 STK_11180 9187fc775173d35f414ab64d818f82c2 464 Pfam PF01979 Amidohydrolase family 51 440 6.4E-26 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 STK_11180 9187fc775173d35f414ab64d818f82c2 464 SUPERFAMILY SSF51556 55 386 1.07E-99 T 23-10-2018 IPR032466 Metal-dependent hydrolase STK_11180 9187fc775173d35f414ab64d818f82c2 464 SUPERFAMILY SSF51338 3 78 4.32E-17 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_11180 9187fc775173d35f414ab64d818f82c2 464 Gene3D G3DSA:3.20.20.140 55 427 5.7E-167 T 23-10-2018 STK_06400 e4706fa9731fefead0dec75872c84706 502 PIRSF PIRSF016493 2 485 5.8E-113 T 23-10-2018 IPR024191 Peptidase M61 STK_06400 e4706fa9731fefead0dec75872c84706 502 Pfam PF05299 M61 glycyl aminopeptidase 213 325 4.3E-34 T 23-10-2018 IPR007963 Peptidase M61, catalytic domain STK_06400 e4706fa9731fefead0dec75872c84706 502 Gene3D G3DSA:2.30.42.10 394 475 2.2E-7 T 23-10-2018 STK_06400 e4706fa9731fefead0dec75872c84706 502 SMART SM00228 403 469 5.6E-4 T 23-10-2018 IPR001478 PDZ domain GO:0005515 STK_06400 e4706fa9731fefead0dec75872c84706 502 SUPERFAMILY SSF50156 390 469 1.04E-9 T 23-10-2018 IPR036034 PDZ superfamily GO:0005515 STK_06400 e4706fa9731fefead0dec75872c84706 502 Gene3D G3DSA:2.60.40.3650 6 138 5.4E-10 T 23-10-2018 STK_06400 e4706fa9731fefead0dec75872c84706 502 Gene3D G3DSA:1.10.390.60 145 381 2.1E-53 T 23-10-2018 STK_06910 0ee1e2a4f443efddcf03a9de6e91db91 446 ProSitePatterns PS00217 Sugar transport proteins signature 2. 104 129 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 STK_06910 0ee1e2a4f443efddcf03a9de6e91db91 446 Pfam PF00083 Sugar (and other) transporter 14 437 4.4E-43 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 STK_06910 0ee1e2a4f443efddcf03a9de6e91db91 446 SUPERFAMILY SSF103473 3 436 3.66E-53 T 23-10-2018 IPR036259 MFS transporter superfamily STK_17480 7e21960ed1de0cde29018ab06b82bf5f 403 Gene3D G3DSA:2.130.10.10 52 202 5.4E-22 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 STK_17480 7e21960ed1de0cde29018ab06b82bf5f 403 Gene3D G3DSA:2.130.10.10 203 389 1.7E-44 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 STK_17480 7e21960ed1de0cde29018ab06b82bf5f 403 SUPERFAMILY SSF50974 16 172 1.41E-15 T 23-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 STK_17480 7e21960ed1de0cde29018ab06b82bf5f 403 SUPERFAMILY SSF51004 130 368 8.89E-44 T 23-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily STK_17480 7e21960ed1de0cde29018ab06b82bf5f 403 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 211 252 7.0E-16 T 23-10-2018 IPR011964 YVTN beta-propeller repeat STK_17480 7e21960ed1de0cde29018ab06b82bf5f 403 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 75 116 4.4E-17 T 23-10-2018 IPR011964 YVTN beta-propeller repeat STK_17480 7e21960ed1de0cde29018ab06b82bf5f 403 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 253 294 5.0E-14 T 23-10-2018 IPR011964 YVTN beta-propeller repeat STK_17480 7e21960ed1de0cde29018ab06b82bf5f 403 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 295 336 3.5E-15 T 23-10-2018 IPR011964 YVTN beta-propeller repeat STK_17480 7e21960ed1de0cde29018ab06b82bf5f 403 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 117 156 4.7E-12 T 23-10-2018 IPR011964 YVTN beta-propeller repeat STK_17480 7e21960ed1de0cde29018ab06b82bf5f 403 SMART SM00135 319 362 25.0 T 23-10-2018 IPR000033 LDLR class B repeat STK_17480 7e21960ed1de0cde29018ab06b82bf5f 403 SMART SM00135 57 100 15.0 T 23-10-2018 IPR000033 LDLR class B repeat STK_17480 7e21960ed1de0cde29018ab06b82bf5f 403 SMART SM00135 235 278 2.6 T 23-10-2018 IPR000033 LDLR class B repeat STK_01910 35f7855a28324267c3e245af4315a743 387 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 204 241 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 STK_01910 35f7855a28324267c3e245af4315a743 387 SUPERFAMILY SSF53383 7 375 3.16E-114 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase STK_01910 35f7855a28324267c3e245af4315a743 387 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 4 374 2.3E-130 T 23-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 STK_01910 35f7855a28324267c3e245af4315a743 387 Pfam PF00202 Aminotransferase class-III 12 372 6.2E-105 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 STK_01910 35f7855a28324267c3e245af4315a743 387 Hamap MF_02084 [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase [lysJ]. 4 378 48.843 T 23-10-2018 IPR037537 [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase GO:0008483 STK_01910 35f7855a28324267c3e245af4315a743 387 Gene3D G3DSA:3.40.640.10 46 286 4.1E-129 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 STK_01910 35f7855a28324267c3e245af4315a743 387 PIRSF PIRSF000521 108 142 0.0017 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 STK_01910 35f7855a28324267c3e245af4315a743 387 PIRSF PIRSF000521 155 379 2.8E-34 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 STK_01910 35f7855a28324267c3e245af4315a743 387 PIRSF PIRSF000521 12 115 2.5E-8 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 STK_01910 35f7855a28324267c3e245af4315a743 387 Gene3D G3DSA:3.90.1150.10 13 369 4.1E-129 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 STK_23670 6f7f7bbc33d923f0f4da08061640673b 289 Gene3D G3DSA:3.60.21.10 2 283 2.2E-67 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like STK_23670 6f7f7bbc33d923f0f4da08061640673b 289 PRINTS PR00114 Serine/threonine phosphatase family signature 248 264 7.0E-18 T 23-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 STK_23670 6f7f7bbc33d923f0f4da08061640673b 289 PRINTS PR00114 Serine/threonine phosphatase family signature 95 119 7.0E-18 T 23-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 STK_23670 6f7f7bbc33d923f0f4da08061640673b 289 PRINTS PR00114 Serine/threonine phosphatase family signature 61 88 7.0E-18 T 23-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 STK_23670 6f7f7bbc33d923f0f4da08061640673b 289 PRINTS PR00114 Serine/threonine phosphatase family signature 129 155 7.0E-18 T 23-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 STK_23670 6f7f7bbc33d923f0f4da08061640673b 289 PRINTS PR00114 Serine/threonine phosphatase family signature 167 194 7.0E-18 T 23-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 STK_23670 6f7f7bbc33d923f0f4da08061640673b 289 ProSitePatterns PS00125 Serine/threonine specific protein phosphatases signature. 96 101 - T 23-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 STK_23670 6f7f7bbc33d923f0f4da08061640673b 289 SUPERFAMILY SSF56300 7 277 1.09E-65 T 23-10-2018 STK_23670 6f7f7bbc33d923f0f4da08061640673b 289 Pfam PF00149 Calcineurin-like phosphoesterase 33 238 6.0E-27 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 STK_23670 6f7f7bbc33d923f0f4da08061640673b 289 SMART SM00156 1 282 4.7E-73 T 23-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 STK_08520 584f9f56560de6ecaf22950d57629ce3 425 PIRSF PIRSF006060 1 423 2.1E-67 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_08520 584f9f56560de6ecaf22950d57629ce3 425 Gene3D G3DSA:1.20.1740.10 1 424 8.1E-76 T 23-10-2018 STK_08520 584f9f56560de6ecaf22950d57629ce3 425 Pfam PF13520 Amino acid permease 6 389 2.4E-40 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_02490 d39f808641563f61291f0ba79fec7a10 217 Pfam PF04693 Archaeal putative transposase ISC1217 1 189 4.9E-92 T 23-10-2018 IPR006783 Transposase, ISC1217 STK_10340 05e8b9dfdfdbbec9a7fd196979e0fcd4 266 ProSitePatterns PS00211 ABC transporters family signature. 114 128 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 STK_10340 05e8b9dfdfdbbec9a7fd196979e0fcd4 266 Gene3D G3DSA:3.40.50.300 1 220 2.6E-50 T 23-10-2018 STK_10340 05e8b9dfdfdbbec9a7fd196979e0fcd4 266 SMART SM00382 26 189 2.8E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_10340 05e8b9dfdfdbbec9a7fd196979e0fcd4 266 Pfam PF00005 ABC transporter 17 141 4.5E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_10340 05e8b9dfdfdbbec9a7fd196979e0fcd4 266 SUPERFAMILY SSF52540 3 200 4.32E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_10200 33ca669d70ac90869b5eb785c333669f 413 SUPERFAMILY SSF51338 1 407 1.49E-24 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_10200 33ca669d70ac90869b5eb785c333669f 413 Gene3D G3DSA:3.20.20.140 50 344 1.6E-94 T 23-10-2018 STK_10200 33ca669d70ac90869b5eb785c333669f 413 Gene3D G3DSA:2.30.40.10 2 408 1.6E-94 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_10200 33ca669d70ac90869b5eb785c333669f 413 Pfam PF01979 Amidohydrolase family 47 397 3.5E-19 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 STK_10200 33ca669d70ac90869b5eb785c333669f 413 SUPERFAMILY SSF51556 50 345 8.18E-52 T 23-10-2018 IPR032466 Metal-dependent hydrolase STK_01530 b08545e2ab7beea77d9094ccb035b9af 339 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 24 288 1.1E-20 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_01530 b08545e2ab7beea77d9094ccb035b9af 339 Gene3D G3DSA:3.40.50.300 1 302 1.2E-21 T 23-10-2018 STK_01530 b08545e2ab7beea77d9094ccb035b9af 339 SUPERFAMILY SSF52540 1 289 8.09E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_03320 5fb1cb959b93c64c79cd6ef03bd988e5 350 Pfam PF16360 GTP-binding GTPase Middle Region 96 171 4.3E-18 T 23-10-2018 IPR032305 GTP-binding protein, middle domain STK_03320 5fb1cb959b93c64c79cd6ef03bd988e5 350 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 178 198 1.2E-5 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 STK_03320 5fb1cb959b93c64c79cd6ef03bd988e5 350 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 199 217 1.2E-5 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 STK_03320 5fb1cb959b93c64c79cd6ef03bd988e5 350 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 244 262 1.2E-5 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 STK_03320 5fb1cb959b93c64c79cd6ef03bd988e5 350 Pfam PF01926 50S ribosome-binding GTPase 178 297 3.7E-19 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 STK_03320 5fb1cb959b93c64c79cd6ef03bd988e5 350 Gene3D G3DSA:3.40.50.300 176 350 1.2E-46 T 23-10-2018 STK_03320 5fb1cb959b93c64c79cd6ef03bd988e5 350 SUPERFAMILY SSF52540 178 350 1.38E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_03320 5fb1cb959b93c64c79cd6ef03bd988e5 350 Gene3D G3DSA:3.40.50.11060 1 96 1.1E-30 T 23-10-2018 STK_03320 5fb1cb959b93c64c79cd6ef03bd988e5 350 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 177 346 3.2E-17 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 STK_03320 5fb1cb959b93c64c79cd6ef03bd988e5 350 PIRSF PIRSF006809 2 350 8.5E-89 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 STK_03320 5fb1cb959b93c64c79cd6ef03bd988e5 350 Pfam PF13167 GTP-binding GTPase N-terminal 10 94 1.1E-11 T 23-10-2018 IPR025121 GTPase HflX, N-terminal STK_03320 5fb1cb959b93c64c79cd6ef03bd988e5 350 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 10 347 9.6E-67 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 STK_21860 1796c1515857d021fd0b87466ec3b4b7 589 SUPERFAMILY SSF56235 2 234 4.12E-68 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_21860 1796c1515857d021fd0b87466ec3b4b7 589 Gene3D G3DSA:3.60.20.10 2 242 2.1E-71 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_21860 1796c1515857d021fd0b87466ec3b4b7 589 Pfam PF01380 SIS domain 448 569 1.2E-19 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 STK_21860 1796c1515857d021fd0b87466ec3b4b7 589 Pfam PF01380 SIS domain 290 412 3.1E-27 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 STK_21860 1796c1515857d021fd0b87466ec3b4b7 589 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 589 8.2E-198 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 STK_21860 1796c1515857d021fd0b87466ec3b4b7 589 Gene3D G3DSA:3.40.50.10490 433 574 2.1E-107 T 23-10-2018 STK_21860 1796c1515857d021fd0b87466ec3b4b7 589 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 589 36.273 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 STK_21860 1796c1515857d021fd0b87466ec3b4b7 589 SUPERFAMILY SSF53697 256 588 5.75E-91 T 23-10-2018 STK_21860 1796c1515857d021fd0b87466ec3b4b7 589 Pfam PF13522 Glutamine amidotransferase domain 67 188 1.7E-21 T 23-10-2018 STK_21860 1796c1515857d021fd0b87466ec3b4b7 589 Gene3D G3DSA:3.40.50.10490 253 588 2.1E-107 T 23-10-2018 STK_04250 5780c53851035583bf523baf38e2d07d 156 Gene3D G3DSA:3.90.470.10 5 156 3.8E-51 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 STK_04250 5780c53851035583bf523baf38e2d07d 156 TIGRFAM TIGR01038 uL22_arch_euk: ribosomal protein uL22 11 155 1.1E-51 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04250 5780c53851035583bf523baf38e2d07d 156 Hamap MF_01331_A 50S ribosomal protein L22 [rplV]. 2 156 32.032 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04250 5780c53851035583bf523baf38e2d07d 156 ProSitePatterns PS00464 Ribosomal protein L22 signature. 129 153 - T 23-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04250 5780c53851035583bf523baf38e2d07d 156 SUPERFAMILY SSF54843 7 155 1.28E-48 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 STK_04250 5780c53851035583bf523baf38e2d07d 156 Pfam PF00237 Ribosomal protein L22p/L17e 20 153 3.3E-31 T 23-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 STK_00910 5be1c20884bc181d00bbbfcacc472bb0 418 ProSitePatterns PS00217 Sugar transport proteins signature 2. 110 135 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 STK_00910 5be1c20884bc181d00bbbfcacc472bb0 418 SUPERFAMILY SSF103473 7 413 2.49E-71 T 23-10-2018 IPR036259 MFS transporter superfamily STK_00910 5be1c20884bc181d00bbbfcacc472bb0 418 ProSitePatterns PS00216 Sugar transport proteins signature 1. 282 298 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 STK_00910 5be1c20884bc181d00bbbfcacc472bb0 418 Gene3D G3DSA:1.20.1250.20 10 417 1.5E-86 T 23-10-2018 STK_00910 5be1c20884bc181d00bbbfcacc472bb0 418 Pfam PF07690 Major Facilitator Superfamily 21 368 1.3E-32 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_00385 1308be062ff0bcfca73205d1805b3c2c 54 SUPERFAMILY SSF50129 2 51 1.45E-14 T 23-10-2018 IPR011032 GroES-like superfamily STK_00385 1308be062ff0bcfca73205d1805b3c2c 54 Gene3D G3DSA:3.90.180.10 1 54 1.4E-14 T 23-10-2018 STK_12060 14e2d66e13ab16234381399bb92e6315 346 Pfam PF01571 Aminomethyltransferase folate-binding domain 9 242 2.6E-62 T 23-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain STK_12060 14e2d66e13ab16234381399bb92e6315 346 PIRSF PIRSF006487 1 346 2.5E-74 T 23-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 STK_12060 14e2d66e13ab16234381399bb92e6315 346 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 3 345 4.0E-77 T 23-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 STK_12060 14e2d66e13ab16234381399bb92e6315 346 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 250 341 1.9E-18 T 23-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 STK_12060 14e2d66e13ab16234381399bb92e6315 346 SUPERFAMILY SSF101790 257 346 3.92E-20 T 23-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal STK_12060 14e2d66e13ab16234381399bb92e6315 346 Gene3D G3DSA:2.40.30.110 264 346 2.2E-18 T 23-10-2018 STK_12060 14e2d66e13ab16234381399bb92e6315 346 Gene3D G3DSA:4.10.1250.10 224 261 1.5E-10 T 23-10-2018 STK_12060 14e2d66e13ab16234381399bb92e6315 346 Gene3D G3DSA:3.30.70.1400 51 134 7.5E-54 T 23-10-2018 STK_12060 14e2d66e13ab16234381399bb92e6315 346 Gene3D G3DSA:3.30.1360.120 5 221 7.5E-54 T 23-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 STK_12060 14e2d66e13ab16234381399bb92e6315 346 SUPERFAMILY SSF103025 3 265 6.41E-62 T 23-10-2018 STK_17930 e5afe943fa8b2edb7eb43c37f60d989f 241 Pfam PF01012 Electron transfer flavoprotein domain 28 196 3.1E-35 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 STK_17930 e5afe943fa8b2edb7eb43c37f60d989f 241 PIRSF PIRSF000090 1 241 2.4E-65 T 23-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 STK_17930 e5afe943fa8b2edb7eb43c37f60d989f 241 SUPERFAMILY SSF52402 1 231 6.56E-57 T 23-10-2018 STK_17930 e5afe943fa8b2edb7eb43c37f60d989f 241 SMART SM00893 19 204 7.8E-35 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 STK_17930 e5afe943fa8b2edb7eb43c37f60d989f 241 Gene3D G3DSA:3.40.50.620 1 234 2.9E-60 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_14180 56c573d7c386145321910b71b24f93ea 227 SMART SM00849 8 191 1.1E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_14180 56c573d7c386145321910b71b24f93ea 227 Gene3D G3DSA:3.60.15.10 3 227 3.5E-64 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_14180 56c573d7c386145321910b71b24f93ea 227 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 2 227 34.826 T 23-10-2018 IPR022877 Protein of unknown funcion UPF0173 STK_14180 56c573d7c386145321910b71b24f93ea 227 SUPERFAMILY SSF56281 3 216 1.04E-34 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_14180 56c573d7c386145321910b71b24f93ea 227 Pfam PF13483 Beta-lactamase superfamily domain 3 191 6.1E-20 T 23-10-2018 STK_16130 4b345c71f3eeafa1e67e623dc72ba59c 439 SMART SM00490 313 414 1.0E-15 T 23-10-2018 IPR001650 Helicase, C-terminal STK_16130 4b345c71f3eeafa1e67e623dc72ba59c 439 Gene3D G3DSA:3.40.50.300 233 429 1.2E-48 T 23-10-2018 STK_16130 4b345c71f3eeafa1e67e623dc72ba59c 439 SUPERFAMILY SSF52540 110 434 3.63E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_16130 4b345c71f3eeafa1e67e623dc72ba59c 439 SMART SM00487 65 229 7.6E-22 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain STK_16130 4b345c71f3eeafa1e67e623dc72ba59c 439 Pfam PF04851 Type III restriction enzyme, res subunit 66 205 5.3E-25 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 STK_16130 4b345c71f3eeafa1e67e623dc72ba59c 439 Gene3D G3DSA:3.40.50.300 56 232 2.5E-45 T 23-10-2018 STK_16130 4b345c71f3eeafa1e67e623dc72ba59c 439 Pfam PF00271 Helicase conserved C-terminal domain 311 413 1.7E-17 T 23-10-2018 IPR001650 Helicase, C-terminal STK_18810 9241822ff77cc566ee5974e897ad3428 182 SUPERFAMILY SSF52833 100 177 7.49E-12 T 23-10-2018 IPR036249 Thioredoxin-like superfamily STK_18810 9241822ff77cc566ee5974e897ad3428 182 Pfam PF13192 Thioredoxin domain 100 168 3.1E-11 T 23-10-2018 IPR012336 Thioredoxin-like fold STK_18810 9241822ff77cc566ee5974e897ad3428 182 Gene3D G3DSA:3.40.30.80 1 171 1.7E-69 T 23-10-2018 STK_22350 67a7079860c41ef35c939b27f28ca988 285 SUPERFAMILY SSF51569 2 268 1.26E-63 T 23-10-2018 STK_22350 67a7079860c41ef35c939b27f28ca988 285 Pfam PF00701 Dihydrodipicolinate synthetase family 2 268 1.1E-50 T 23-10-2018 IPR002220 DapA-like GO:0016829 STK_22350 67a7079860c41ef35c939b27f28ca988 285 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 3.7E-10 T 23-10-2018 IPR002220 DapA-like GO:0016829 STK_22350 67a7079860c41ef35c939b27f28ca988 285 PRINTS PR00146 Dihydrodipicolinate synthase signature 67 85 3.7E-10 T 23-10-2018 IPR002220 DapA-like GO:0016829 STK_22350 67a7079860c41ef35c939b27f28ca988 285 PRINTS PR00146 Dihydrodipicolinate synthase signature 99 115 3.7E-10 T 23-10-2018 IPR002220 DapA-like GO:0016829 STK_22350 67a7079860c41ef35c939b27f28ca988 285 SMART SM01130 1 284 1.3E-63 T 23-10-2018 IPR002220 DapA-like GO:0016829 STK_22350 67a7079860c41ef35c939b27f28ca988 285 PIRSF PIRSF001365 1 284 1.0E-61 T 23-10-2018 IPR002220 DapA-like GO:0016829 STK_22350 67a7079860c41ef35c939b27f28ca988 285 Gene3D G3DSA:3.20.20.70 1 275 2.4E-68 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_02190 f77dd964a7aac7b4f167abe410290cca 546 SUPERFAMILY SSF53649 2 521 4.8E-45 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 STK_02190 f77dd964a7aac7b4f167abe410290cca 546 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 275 481 9.3E-11 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 STK_02190 f77dd964a7aac7b4f167abe410290cca 546 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 3 107 1.1E-16 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 STK_14800 967c720661ca32c9e30e3ad8c05a3beb 298 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 295 1.0E-106 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 STK_14800 967c720661ca32c9e30e3ad8c05a3beb 298 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 298 35.418 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 STK_14800 967c720661ca32c9e30e3ad8c05a3beb 298 Gene3D G3DSA:3.40.50.1370 129 276 1.4E-110 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 STK_14800 967c720661ca32c9e30e3ad8c05a3beb 298 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 251 260 1.1E-20 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 STK_14800 967c720661ca32c9e30e3ad8c05a3beb 298 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 261 284 1.1E-20 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 STK_14800 967c720661ca32c9e30e3ad8c05a3beb 298 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 44 63 1.1E-20 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 STK_14800 967c720661ca32c9e30e3ad8c05a3beb 298 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 128 139 1.1E-20 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 STK_14800 967c720661ca32c9e30e3ad8c05a3beb 298 PRINTS PR00101 Aspartate carbamoyltransferase signature 216 225 1.6E-29 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 STK_14800 967c720661ca32c9e30e3ad8c05a3beb 298 PRINTS PR00101 Aspartate carbamoyltransferase signature 127 144 1.6E-29 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 STK_14800 967c720661ca32c9e30e3ad8c05a3beb 298 PRINTS PR00101 Aspartate carbamoyltransferase signature 34 56 1.6E-29 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 STK_14800 967c720661ca32c9e30e3ad8c05a3beb 298 PRINTS PR00101 Aspartate carbamoyltransferase signature 73 82 1.6E-29 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 STK_14800 967c720661ca32c9e30e3ad8c05a3beb 298 PRINTS PR00101 Aspartate carbamoyltransferase signature 255 260 1.6E-29 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 STK_14800 967c720661ca32c9e30e3ad8c05a3beb 298 PRINTS PR00101 Aspartate carbamoyltransferase signature 277 291 1.6E-29 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 STK_14800 967c720661ca32c9e30e3ad8c05a3beb 298 SUPERFAMILY SSF53671 2 297 4.06E-92 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 STK_14800 967c720661ca32c9e30e3ad8c05a3beb 298 Gene3D G3DSA:3.40.50.1370 3 291 1.4E-110 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 STK_14800 967c720661ca32c9e30e3ad8c05a3beb 298 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 140 2.2E-42 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 STK_14800 967c720661ca32c9e30e3ad8c05a3beb 298 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 147 293 2.5E-27 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 STK_14800 967c720661ca32c9e30e3ad8c05a3beb 298 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 44 51 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 STK_14970 1ea0296d3daef6daef009ce753918dc4 403 Gene3D G3DSA:3.40.50.2020 221 385 1.7E-84 T 23-10-2018 STK_14970 1ea0296d3daef6daef009ce753918dc4 403 SUPERFAMILY SSF56235 3 203 8.49E-17 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_14970 1ea0296d3daef6daef009ce753918dc4 403 Pfam PF00156 Phosphoribosyl transferase domain 226 332 1.7E-9 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 STK_14970 1ea0296d3daef6daef009ce753918dc4 403 Gene3D G3DSA:3.60.20.10 105 400 1.7E-84 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_14970 1ea0296d3daef6daef009ce753918dc4 403 PIRSF PIRSF000485 80 403 4.0E-100 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 STK_14970 1ea0296d3daef6daef009ce753918dc4 403 PIRSF PIRSF000485 1 77 3.2E-6 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 STK_14970 1ea0296d3daef6daef009ce753918dc4 403 SUPERFAMILY SSF53271 197 400 6.16E-53 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like STK_25750 da94be5b2a0a6ed19ce94eb7caf8d237 544 Gene3D G3DSA:3.30.300.30 439 544 8.9E-31 T 23-10-2018 STK_25750 da94be5b2a0a6ed19ce94eb7caf8d237 544 ProSitePatterns PS00455 Putative AMP-binding domain signature. 193 204 - T 23-10-2018 IPR020845 AMP-binding, conserved site STK_25750 da94be5b2a0a6ed19ce94eb7caf8d237 544 Pfam PF00501 AMP-binding enzyme 45 444 8.1E-84 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 STK_25750 da94be5b2a0a6ed19ce94eb7caf8d237 544 Pfam PF13193 AMP-binding enzyme C-terminal domain 452 530 4.3E-24 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain STK_25750 da94be5b2a0a6ed19ce94eb7caf8d237 544 SUPERFAMILY SSF56801 11 542 1.57E-138 T 23-10-2018 STK_25750 da94be5b2a0a6ed19ce94eb7caf8d237 544 Gene3D G3DSA:3.40.50.12780 3 437 2.0E-107 T 23-10-2018 STK_02807 cb1cc6ce03200d0f11e2c8297ef77f91 83 Hamap MF_00292 30S ribosomal protein S28e [rps28e]. 1 80 25.588 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_02807 cb1cc6ce03200d0f11e2c8297ef77f91 83 SUPERFAMILY SSF50249 17 81 1.71E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_02807 cb1cc6ce03200d0f11e2c8297ef77f91 83 Gene3D G3DSA:2.40.50.140 13 83 1.8E-32 T 23-10-2018 STK_02807 cb1cc6ce03200d0f11e2c8297ef77f91 83 Pfam PF01200 Ribosomal protein S28e 19 79 2.3E-31 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_02807 cb1cc6ce03200d0f11e2c8297ef77f91 83 ProDom PD005541 RIBOSOMAL RIBONUCLEOPROTEIN 40S S28 S28E 30S ACETYLATION S33 S33 CG15527 21 61 2.0E-15 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_02807 cb1cc6ce03200d0f11e2c8297ef77f91 83 ProSitePatterns PS00961 Ribosomal protein S28e signature. 71 79 - T 23-10-2018 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_22615 3e874a183b8231cd7a48e9b484906b16 93 Hamap MF_00261 DNA-directed RNA polymerase subunit L [rpoL]. 1 87 19.875 T 23-10-2018 IPR022905 DNA-directed RNA polymerase subunit L (Rpo11) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_22615 3e874a183b8231cd7a48e9b484906b16 93 ProSitePatterns PS01154 RNA polymerases L / 13 to 16 Kd subunits signature. 17 48 - T 23-10-2018 IPR008193 DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 STK_22615 3e874a183b8231cd7a48e9b484906b16 93 Gene3D G3DSA:3.30.1360.10 1 92 2.5E-30 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_22615 3e874a183b8231cd7a48e9b484906b16 93 Pfam PF13656 RNA polymerase Rpb3/Rpb11 dimerisation domain 13 85 2.0E-21 T 23-10-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 STK_22615 3e874a183b8231cd7a48e9b484906b16 93 SUPERFAMILY SSF55257 2 88 1.7E-25 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_06350 3c4dce80921b2ef16bf707f55465f43c 524 Pfam PF00474 Sodium:solute symporter family 46 445 2.7E-12 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 STK_06350 3c4dce80921b2ef16bf707f55465f43c 524 Gene3D G3DSA:1.20.1730.10 35 511 4.4E-24 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily STK_15800 dd4230dcebbebe5ffc9ec534621c0d6a 394 SUPERFAMILY SSF51556 49 343 5.57E-75 T 23-10-2018 IPR032466 Metal-dependent hydrolase STK_15800 dd4230dcebbebe5ffc9ec534621c0d6a 394 Gene3D G3DSA:3.20.20.140 50 344 5.6E-103 T 23-10-2018 STK_15800 dd4230dcebbebe5ffc9ec534621c0d6a 394 SUPERFAMILY SSF51338 6 390 6.01E-10 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_15800 dd4230dcebbebe5ffc9ec534621c0d6a 394 Pfam PF01979 Amidohydrolase family 45 384 7.3E-48 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 STK_15800 dd4230dcebbebe5ffc9ec534621c0d6a 394 Gene3D G3DSA:2.30.40.10 10 383 5.6E-103 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_03420 0123e5c5b24d4a705fad1dd3ee29cdb4 415 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 3 415 3.9E-199 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 STK_03420 0123e5c5b24d4a705fad1dd3ee29cdb4 415 SMART SM00996 2 414 3.6E-162 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 STK_03420 0123e5c5b24d4a705fad1dd3ee29cdb4 415 SMART SM00997 182 343 1.6E-112 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 STK_03420 0123e5c5b24d4a705fad1dd3ee29cdb4 415 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 74 88 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 STK_03420 0123e5c5b24d4a705fad1dd3ee29cdb4 415 SUPERFAMILY SSF52283 1 415 1.47E-99 T 23-10-2018 STK_03420 0123e5c5b24d4a705fad1dd3ee29cdb4 415 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 2 135 1.9E-45 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 STK_03420 0123e5c5b24d4a705fad1dd3ee29cdb4 415 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 204 220 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 STK_03420 0123e5c5b24d4a705fad1dd3ee29cdb4 415 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 141 409 3.5E-27 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 STK_03420 0123e5c5b24d4a705fad1dd3ee29cdb4 415 PIRSF PIRSF001109 1 415 2.8E-193 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 STK_03420 0123e5c5b24d4a705fad1dd3ee29cdb4 415 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 184 342 1.8E-57 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 STK_03420 0123e5c5b24d4a705fad1dd3ee29cdb4 415 Gene3D G3DSA:3.40.50.1480 5 404 3.3E-179 T 23-10-2018 STK_03420 0123e5c5b24d4a705fad1dd3ee29cdb4 415 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 1 415 50.157 T 23-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 STK_03420 0123e5c5b24d4a705fad1dd3ee29cdb4 415 SUPERFAMILY SSF51735 182 344 1.77E-68 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_03420 0123e5c5b24d4a705fad1dd3ee29cdb4 415 Gene3D G3DSA:3.40.50.720 184 343 3.3E-179 T 23-10-2018 STK_14220 289bc40290e079a65558a03ce2eb840c 228 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 96 6.1E-11 T 23-10-2018 STK_14220 289bc40290e079a65558a03ce2eb840c 228 Pfam PF08282 haloacid dehalogenase-like hydrolase 131 215 5.0E-20 T 23-10-2018 STK_14220 289bc40290e079a65558a03ce2eb840c 228 Gene3D G3DSA:3.90.1070.10 81 142 2.1E-58 T 23-10-2018 STK_14220 289bc40290e079a65558a03ce2eb840c 228 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 5 219 5.3E-35 T 23-10-2018 STK_14220 289bc40290e079a65558a03ce2eb840c 228 SUPERFAMILY SSF56784 2 220 8.64E-46 T 23-10-2018 IPR036412 HAD-like superfamily STK_14220 289bc40290e079a65558a03ce2eb840c 228 Hamap MF_01419 Phosphoglycolate phosphatase. 2 221 27.063 T 23-10-2018 IPR006382 Phosphoglycolate phosphatase GO:0000287|GO:0008967|GO:0016311 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 STK_14220 289bc40290e079a65558a03ce2eb840c 228 Gene3D G3DSA:3.40.50.1000 5 208 2.1E-58 T 23-10-2018 IPR023214 HAD superfamily STK_14220 289bc40290e079a65558a03ce2eb840c 228 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 2 216 3.4E-67 T 23-10-2018 STK_11320 d092eda1d51ecc61b291190d757abcd1 435 SUPERFAMILY SSF103473 7 435 6.93E-43 T 23-10-2018 IPR036259 MFS transporter superfamily STK_11320 d092eda1d51ecc61b291190d757abcd1 435 Gene3D G3DSA:1.20.1250.20 245 431 4.1E-7 T 23-10-2018 STK_11320 d092eda1d51ecc61b291190d757abcd1 435 Pfam PF07690 Major Facilitator Superfamily 22 378 2.1E-19 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_11320 d092eda1d51ecc61b291190d757abcd1 435 Gene3D G3DSA:1.20.1250.20 12 234 1.0E-28 T 23-10-2018 STK_25410 552a8477e681b1960fb4f35f965fdb1d 358 Gene3D G3DSA:1.10.3720.10 145 352 2.5E-18 T 23-10-2018 IPR035906 MetI-like superfamily STK_25410 552a8477e681b1960fb4f35f965fdb1d 358 SUPERFAMILY SSF161098 161 338 4.36E-23 T 23-10-2018 IPR035906 MetI-like superfamily STK_25410 552a8477e681b1960fb4f35f965fdb1d 358 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 173 357 2.0E-26 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 STK_14240 dc80a0e3ce9839e9d99f7b13922fed6f 126 Gene3D G3DSA:3.30.1330.30 1 126 4.0E-48 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like STK_14240 dc80a0e3ce9839e9d99f7b13922fed6f 126 Hamap MF_00326 50S ribosomal protein L7Ae [rpl7ae]. 3 122 33.817 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_14240 dc80a0e3ce9839e9d99f7b13922fed6f 126 TIGRFAM TIGR03677 eL8_ribo: ribosomal protein eL8 6 122 1.7E-57 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_14240 dc80a0e3ce9839e9d99f7b13922fed6f 126 SUPERFAMILY SSF55315 4 121 4.27E-42 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like STK_14240 dc80a0e3ce9839e9d99f7b13922fed6f 126 ProSitePatterns PS01082 Ribosomal protein L7Ae signature. 70 87 - T 23-10-2018 IPR004037 Ribosomal protein L7Ae conserved site GO:0042254|GO:1990904 Reactome: R-HSA-6791226 STK_14240 dc80a0e3ce9839e9d99f7b13922fed6f 126 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 32 46 5.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family STK_14240 dc80a0e3ce9839e9d99f7b13922fed6f 126 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 51 64 5.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family STK_14240 dc80a0e3ce9839e9d99f7b13922fed6f 126 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 77 91 5.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family STK_14240 dc80a0e3ce9839e9d99f7b13922fed6f 126 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 67 77 5.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family STK_14240 dc80a0e3ce9839e9d99f7b13922fed6f 126 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 18 110 7.0E-34 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 STK_14240 dc80a0e3ce9839e9d99f7b13922fed6f 126 PRINTS PR00884 Ribosomal protein HS6 signature 40 50 2.3E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_14240 dc80a0e3ce9839e9d99f7b13922fed6f 126 PRINTS PR00884 Ribosomal protein HS6 signature 77 87 2.3E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_14240 dc80a0e3ce9839e9d99f7b13922fed6f 126 PRINTS PR00884 Ribosomal protein HS6 signature 6 17 2.3E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_14240 dc80a0e3ce9839e9d99f7b13922fed6f 126 PRINTS PR00884 Ribosomal protein HS6 signature 50 61 2.3E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_14240 dc80a0e3ce9839e9d99f7b13922fed6f 126 PRINTS PR00884 Ribosomal protein HS6 signature 91 107 2.3E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_26090 b43f15860c70359d5b3cf2c15303246d 661 Pfam PF12215 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term 20 273 6.3E-21 T 23-10-2018 IPR024462 Glycosyl-hydrolase family 116, N-terminal KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 STK_26090 b43f15860c70359d5b3cf2c15303246d 661 SUPERFAMILY SSF48208 278 571 1.77E-31 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 STK_26090 b43f15860c70359d5b3cf2c15303246d 661 Gene3D G3DSA:1.50.10.10 341 632 3.4E-16 T 23-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 STK_26090 b43f15860c70359d5b3cf2c15303246d 661 Pfam PF04685 Glycosyl-hydrolase family 116, catalytic region 313 641 2.8E-57 T 23-10-2018 IPR006775 Glycosyl-hydrolase family 116, catalytic region GO:0004553 KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 STK_20670 d4d0bef992f0b30986c9584f1b907e05 264 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 204 215 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_20670 d4d0bef992f0b30986c9584f1b907e05 264 SMART SM00662 12 260 1.5E-85 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_20670 d4d0bef992f0b30986c9584f1b907e05 264 ProSitePatterns PS00446 RNA polymerases D / 30 to 40 Kd subunits signature. 26 66 - T 23-10-2018 IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 STK_20670 d4d0bef992f0b30986c9584f1b907e05 264 Gene3D G3DSA:3.30.70.20 168 224 6.5E-90 T 23-10-2018 STK_20670 d4d0bef992f0b30986c9584f1b907e05 264 Gene3D G3DSA:2.170.120.12 38 157 6.5E-90 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_20670 d4d0bef992f0b30986c9584f1b907e05 264 Hamap MF_00320 DNA-directed RNA polymerase subunit D [rpoD]. 1 263 32.228 T 23-10-2018 IPR022842 DNA-directed RNA polymerase subunit D (Rpo3) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_20670 d4d0bef992f0b30986c9584f1b907e05 264 SUPERFAMILY SSF56553 37 159 3.66E-32 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_20670 d4d0bef992f0b30986c9584f1b907e05 264 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 19 254 2.1E-10 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_20670 d4d0bef992f0b30986c9584f1b907e05 264 Gene3D G3DSA:3.30.1360.10 10 257 6.5E-90 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_20670 d4d0bef992f0b30986c9584f1b907e05 264 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 44 158 1.1E-25 T 23-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_20670 d4d0bef992f0b30986c9584f1b907e05 264 SUPERFAMILY SSF55257 3 263 8.04E-28 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_06170 a625a6987f5cc72e9ae9951ef2c4c68f 373 PIRSF PIRSF032888 1 371 6.0E-210 T 23-10-2018 IPR017011 Uncharacterised conserved protein UCP032888 STK_06170 a625a6987f5cc72e9ae9951ef2c4c68f 373 Pfam PF07849 Protein of unknown function (DUF1641) 330 366 9.8E-13 T 23-10-2018 IPR012440 Protein of unknown function DUF1641 STK_07560 7e16840e5ee52f07822cea9da5f3fdf4 306 SUPERFAMILY SSF52540 2 229 4.6E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_07560 7e16840e5ee52f07822cea9da5f3fdf4 306 Gene3D G3DSA:3.40.50.300 1 242 3.8E-62 T 23-10-2018 STK_07560 7e16840e5ee52f07822cea9da5f3fdf4 306 Pfam PF00005 ABC transporter 21 165 2.1E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_07560 7e16840e5ee52f07822cea9da5f3fdf4 306 SMART SM00382 30 221 5.1E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_22290 c0af0dea5dcfbbbdcf9f44c4f9dc52b3 184 SUPERFAMILY SSF56349 71 182 7.06E-13 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 STK_22290 c0af0dea5dcfbbbdcf9f44c4f9dc52b3 184 Gene3D G3DSA:1.10.443.10 118 184 6.1E-12 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 STK_22290 c0af0dea5dcfbbbdcf9f44c4f9dc52b3 184 Pfam PF00589 Phage integrase family 132 181 3.5E-9 T 23-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 STK_02110 e3df9685fa81c10e7d68d0aa638aec96 215 SUPERFAMILY SSF51735 5 116 4.82E-19 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_02110 e3df9685fa81c10e7d68d0aa638aec96 215 Pfam PF13241 Putative NAD(P)-binding 9 118 4.3E-23 T 23-10-2018 STK_02110 e3df9685fa81c10e7d68d0aa638aec96 215 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 7 208 9.8E-21 T 23-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 STK_02110 e3df9685fa81c10e7d68d0aa638aec96 215 SUPERFAMILY SSF75615 118 203 1.24E-11 T 23-10-2018 STK_02110 e3df9685fa81c10e7d68d0aa638aec96 215 Gene3D G3DSA:3.40.50.720 6 134 7.1E-29 T 23-10-2018 STK_05480 9ba17358f68593d24dff18c6d3cbdfe0 605 ProSitePatterns PS00674 AAA-protein family signature. 481 499 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 STK_05480 9ba17358f68593d24dff18c6d3cbdfe0 605 Gene3D G3DSA:3.40.50.300 53 230 2.6E-64 T 23-10-2018 STK_05480 9ba17358f68593d24dff18c6d3cbdfe0 605 Gene3D G3DSA:1.10.8.60 512 603 1.9E-19 T 23-10-2018 STK_05480 9ba17358f68593d24dff18c6d3cbdfe0 605 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 382 510 6.2E-41 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_05480 9ba17358f68593d24dff18c6d3cbdfe0 605 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 98 228 6.6E-40 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_05480 9ba17358f68593d24dff18c6d3cbdfe0 605 Pfam PF09336 Vps4 C terminal oligomerisation domain 287 321 2.2E-5 T 23-10-2018 IPR015415 Vps4 oligomerisation, C-terminal STK_05480 9ba17358f68593d24dff18c6d3cbdfe0 605 SUPERFAMILY SSF52540 340 596 5.35E-62 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_05480 9ba17358f68593d24dff18c6d3cbdfe0 605 SUPERFAMILY SSF52540 56 319 1.15E-71 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_05480 9ba17358f68593d24dff18c6d3cbdfe0 605 Gene3D G3DSA:1.10.8.60 231 326 2.5E-25 T 23-10-2018 STK_05480 9ba17358f68593d24dff18c6d3cbdfe0 605 SMART SM00382 94 231 1.5E-23 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_05480 9ba17358f68593d24dff18c6d3cbdfe0 605 SMART SM00382 378 513 1.3E-19 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_05480 9ba17358f68593d24dff18c6d3cbdfe0 605 Gene3D G3DSA:3.40.50.300 334 511 8.2E-59 T 23-10-2018 STK_14940 4b584fad05f03cf0224b8eec0bc1321c 223 Gene3D G3DSA:3.40.50.880 1 223 1.2E-64 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_14940 4b584fad05f03cf0224b8eec0bc1321c 223 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 205 4.7E-42 T 23-10-2018 STK_14940 4b584fad05f03cf0224b8eec0bc1321c 223 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 223 38.676 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 STK_14940 4b584fad05f03cf0224b8eec0bc1321c 223 SMART SM01211 1 222 1.3E-91 T 23-10-2018 STK_14940 4b584fad05f03cf0224b8eec0bc1321c 223 SUPERFAMILY SSF52317 2 223 3.37E-63 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_14940 4b584fad05f03cf0224b8eec0bc1321c 223 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 2 221 6.0E-91 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 STK_14940 4b584fad05f03cf0224b8eec0bc1321c 223 PIRSF PIRSF001586 1 223 4.5E-73 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 STK_04000 de13f6baee9a975f6209c08232295717 553 SUPERFAMILY SSF52540 221 539 4.12E-26 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_04000 de13f6baee9a975f6209c08232295717 553 SMART SM00382 235 504 8.2E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_04000 de13f6baee9a975f6209c08232295717 553 Pfam PF01935 Domain of unknown function DUF87 228 427 8.5E-9 T 23-10-2018 IPR002789 Helicase HerA, central domain STK_04000 de13f6baee9a975f6209c08232295717 553 Gene3D G3DSA:3.40.50.300 350 546 1.3E-20 T 23-10-2018 STK_04000 de13f6baee9a975f6209c08232295717 553 Gene3D G3DSA:3.40.50.300 218 325 7.8E-8 T 23-10-2018 STK_18670 15d85520406f852b911fbb0ec42d69ff 127 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 22 97 8.0E-16 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal STK_18670 15d85520406f852b911fbb0ec42d69ff 127 SUPERFAMILY SSF46785 18 121 3.09E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_18670 15d85520406f852b911fbb0ec42d69ff 127 SMART SM00347 21 122 0.0055 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 STK_18670 15d85520406f852b911fbb0ec42d69ff 127 Gene3D G3DSA:1.10.10.10 14 116 1.9E-31 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_10750 7f6f84156f138e08b616162a96180a29 453 PIRSF PIRSF000350 1 453 2.3E-128 T 23-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 STK_10750 7f6f84156f138e08b616162a96180a29 453 Gene3D G3DSA:3.30.390.30 329 453 3.7E-37 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 STK_10750 7f6f84156f138e08b616162a96180a29 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 123 141 2.8E-28 T 23-10-2018 STK_10750 7f6f84156f138e08b616162a96180a29 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 2.8E-28 T 23-10-2018 STK_10750 7f6f84156f138e08b616162a96180a29 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 247 263 2.8E-28 T 23-10-2018 STK_10750 7f6f84156f138e08b616162a96180a29 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 2.8E-28 T 23-10-2018 STK_10750 7f6f84156f138e08b616162a96180a29 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 2.8E-28 T 23-10-2018 STK_10750 7f6f84156f138e08b616162a96180a29 453 Gene3D G3DSA:3.50.50.60 135 254 1.4E-104 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_10750 7f6f84156f138e08b616162a96180a29 453 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 309 4.5E-58 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 STK_10750 7f6f84156f138e08b616162a96180a29 453 SUPERFAMILY SSF51905 1 349 1.75E-44 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_10750 7f6f84156f138e08b616162a96180a29 453 TIGRFAM TIGR02053 MerA: mercury(II) reductase 1 453 8.7E-202 T 23-10-2018 IPR021179 Mercury(II) reductase GO:0016152|GO:0016491|GO:0045340|GO:0050660|GO:0050661|GO:0050787|GO:0055114 STK_10750 7f6f84156f138e08b616162a96180a29 453 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 330 437 1.3E-27 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 STK_10750 7f6f84156f138e08b616162a96180a29 453 SUPERFAMILY SSF55424 329 452 6.53E-33 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 STK_10750 7f6f84156f138e08b616162a96180a29 453 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 35 45 - T 23-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 STK_10750 7f6f84156f138e08b616162a96180a29 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 1.9E-57 T 23-10-2018 STK_10750 7f6f84156f138e08b616162a96180a29 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 248 262 1.9E-57 T 23-10-2018 STK_10750 7f6f84156f138e08b616162a96180a29 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 126 135 1.9E-57 T 23-10-2018 STK_10750 7f6f84156f138e08b616162a96180a29 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 326 347 1.9E-57 T 23-10-2018 STK_10750 7f6f84156f138e08b616162a96180a29 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 390 405 1.9E-57 T 23-10-2018 STK_10750 7f6f84156f138e08b616162a96180a29 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 34 49 1.9E-57 T 23-10-2018 STK_10750 7f6f84156f138e08b616162a96180a29 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 162 187 1.9E-57 T 23-10-2018 STK_10750 7f6f84156f138e08b616162a96180a29 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 412 432 1.9E-57 T 23-10-2018 STK_10750 7f6f84156f138e08b616162a96180a29 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 297 1.9E-57 T 23-10-2018 STK_10750 7f6f84156f138e08b616162a96180a29 453 Gene3D G3DSA:3.50.50.60 4 314 1.4E-104 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_18870 9975be0b5d04e65cb036d4099e044972 296 SUPERFAMILY SSF102114 4 227 6.15E-25 T 23-10-2018 STK_18870 9975be0b5d04e65cb036d4099e044972 296 Pfam PF04055 Radical SAM superfamily 30 174 7.1E-11 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_18870 9975be0b5d04e65cb036d4099e044972 296 SMART SM00729 25 225 1.3E-14 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 STK_18870 9975be0b5d04e65cb036d4099e044972 296 Gene3D G3DSA:3.20.20.70 23 240 1.1E-11 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_23550 9cab69462d84f141ab97ceeb1573cd3b 478 Gene3D G3DSA:3.60.20.40 316 476 1.6E-24 T 23-10-2018 STK_23550 9cab69462d84f141ab97ceeb1573cd3b 478 Pfam PF01019 Gamma-glutamyltranspeptidase 23 452 9.5E-80 T 23-10-2018 STK_23550 9cab69462d84f141ab97ceeb1573cd3b 478 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 110 129 1.2E-18 T 23-10-2018 STK_23550 9cab69462d84f141ab97ceeb1573cd3b 478 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 92 110 1.2E-18 T 23-10-2018 STK_23550 9cab69462d84f141ab97ceeb1573cd3b 478 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 365 380 1.2E-18 T 23-10-2018 STK_23550 9cab69462d84f141ab97ceeb1573cd3b 478 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 30 55 1.2E-18 T 23-10-2018 STK_23550 9cab69462d84f141ab97ceeb1573cd3b 478 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 229 248 1.2E-18 T 23-10-2018 STK_23550 9cab69462d84f141ab97ceeb1573cd3b 478 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 200 216 1.2E-18 T 23-10-2018 STK_23550 9cab69462d84f141ab97ceeb1573cd3b 478 Gene3D G3DSA:1.10.246.230 216 314 7.4E-19 T 23-10-2018 STK_23550 9cab69462d84f141ab97ceeb1573cd3b 478 SUPERFAMILY SSF56235 4 475 9.26E-109 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_03140 affdca6351b8c1e28a67f172ab3d4710 862 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 8 147 1.4E-11 T 23-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal STK_03140 affdca6351b8c1e28a67f172ab3d4710 862 Pfam PF08706 D5 N terminal like 364 515 1.4E-15 T 23-10-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal STK_03140 affdca6351b8c1e28a67f172ab3d4710 862 Gene3D G3DSA:1.10.1200.130 1 61 2.4E-25 T 23-10-2018 STK_03140 affdca6351b8c1e28a67f172ab3d4710 862 SMART SM00885 351 510 1.9E-10 T 23-10-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal STK_03140 affdca6351b8c1e28a67f172ab3d4710 862 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 517 764 1.7E-45 T 23-10-2018 IPR006500 DNA primase, phage/plasmid STK_03140 affdca6351b8c1e28a67f172ab3d4710 862 SUPERFAMILY SSF56747 2 206 1.96E-74 T 23-10-2018 STK_03140 affdca6351b8c1e28a67f172ab3d4710 862 SUPERFAMILY SSF52540 490 663 4.48E-16 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_03140 affdca6351b8c1e28a67f172ab3d4710 862 Gene3D G3DSA:1.10.1240.50 221 330 3.7E-37 T 23-10-2018 STK_03140 affdca6351b8c1e28a67f172ab3d4710 862 Gene3D G3DSA:1.10.10.10 728 798 7.9E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_03140 affdca6351b8c1e28a67f172ab3d4710 862 SUPERFAMILY SSF46785 729 797 8.03E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_03140 affdca6351b8c1e28a67f172ab3d4710 862 Pfam PF13010 Primase helical domain 223 329 9.0E-19 T 23-10-2018 IPR024966 Primase helical domain STK_03140 affdca6351b8c1e28a67f172ab3d4710 862 SMART SM00943 7 205 1.7E-43 T 23-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal STK_03140 affdca6351b8c1e28a67f172ab3d4710 862 Gene3D G3DSA:3.30.2250.10 62 220 3.2E-74 T 23-10-2018 STK_03140 affdca6351b8c1e28a67f172ab3d4710 862 Pfam PF02257 RFX DNA-binding domain 737 797 2.4E-6 T 23-10-2018 IPR003150 DNA-binding RFX-type winged-helix domain GO:0003677|GO:0006355 STK_03140 affdca6351b8c1e28a67f172ab3d4710 862 Gene3D G3DSA:3.40.50.300 516 686 3.8E-12 T 23-10-2018 STK_00430 df78e1cf7af0fefae5c8f94129763fea 136 SMART SM01321 10 128 9.0E-47 T 23-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 STK_00430 df78e1cf7af0fefae5c8f94129763fea 136 Pfam PF01797 Transposase IS200 like 11 128 2.7E-42 T 23-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 STK_00430 df78e1cf7af0fefae5c8f94129763fea 136 Gene3D G3DSA:3.30.70.1290 1 136 7.1E-52 T 23-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 STK_00430 df78e1cf7af0fefae5c8f94129763fea 136 SUPERFAMILY SSF143422 2 128 1.29E-49 T 23-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 STK_25530 df78e1cf7af0fefae5c8f94129763fea 136 SMART SM01321 10 128 9.0E-47 T 23-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 STK_25530 df78e1cf7af0fefae5c8f94129763fea 136 Pfam PF01797 Transposase IS200 like 11 128 2.7E-42 T 23-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 STK_25530 df78e1cf7af0fefae5c8f94129763fea 136 Gene3D G3DSA:3.30.70.1290 1 136 7.1E-52 T 23-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 STK_25530 df78e1cf7af0fefae5c8f94129763fea 136 SUPERFAMILY SSF143422 2 128 1.29E-49 T 23-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 STK_00840 12c45b8f16c5e4301dfe58b647527cb6 255 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 21 254 4.2E-57 T 23-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 STK_00840 12c45b8f16c5e4301dfe58b647527cb6 255 PIRSF PIRSF015626 1 255 4.8E-82 T 23-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 STK_00840 12c45b8f16c5e4301dfe58b647527cb6 255 Gene3D G3DSA:3.10.20.10 36 108 5.7E-10 T 23-10-2018 STK_00840 12c45b8f16c5e4301dfe58b647527cb6 255 Pfam PF02634 FdhD/NarQ family 24 254 1.2E-73 T 23-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 STK_00840 12c45b8f16c5e4301dfe58b647527cb6 255 SUPERFAMILY SSF53927 4 255 1.23E-74 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 STK_00840 12c45b8f16c5e4301dfe58b647527cb6 255 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 2 255 34.081 T 23-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 STK_00840 12c45b8f16c5e4301dfe58b647527cb6 255 Gene3D G3DSA:3.40.140.10 112 255 1.6E-49 T 23-10-2018 STK_02860 4d44b0c995d3764b5c6386acf314cf0a 582 SUPERFAMILY SSF102114 126 401 7.59E-39 T 23-10-2018 STK_02860 4d44b0c995d3764b5c6386acf314cf0a 582 Pfam PF13394 4Fe-4S single cluster domain 143 228 1.3E-6 T 23-10-2018 STK_02860 4d44b0c995d3764b5c6386acf314cf0a 582 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 143 154 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 STK_02860 4d44b0c995d3764b5c6386acf314cf0a 582 Gene3D G3DSA:3.20.20.70 128 404 6.3E-31 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_02860 4d44b0c995d3764b5c6386acf314cf0a 582 Pfam PF04055 Radical SAM superfamily 142 306 3.3E-20 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_16600 a533255dd698e6fc9287e935271ae6ae 478 PIRSF PIRSF006060 3 478 7.1E-17 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_16600 a533255dd698e6fc9287e935271ae6ae 478 Gene3D G3DSA:1.20.1740.10 10 467 1.5E-14 T 23-10-2018 STK_16600 a533255dd698e6fc9287e935271ae6ae 478 Pfam PF00324 Amino acid permease 37 399 6.4E-6 T 23-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 STK_05630 c873f83396dd3156a284a72099feac74 239 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 2 232 2.3E-81 T 23-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 STK_05630 c873f83396dd3156a284a72099feac74 239 Gene3D G3DSA:3.30.950.10 115 239 2.1E-33 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 STK_05630 c873f83396dd3156a284a72099feac74 239 SUPERFAMILY SSF53790 2 238 2.22E-63 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 STK_05630 c873f83396dd3156a284a72099feac74 239 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 208 1.2E-43 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 STK_05630 c873f83396dd3156a284a72099feac74 239 Gene3D G3DSA:3.40.1010.10 1 114 6.9E-40 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 STK_05630 c873f83396dd3156a284a72099feac74 239 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 23-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 STK_05630 c873f83396dd3156a284a72099feac74 239 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 79 112 - T 23-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 STK_14370 70dd6bc89af32514c1cac82c99b7eca8 465 SUPERFAMILY SSF47917 366 420 3.69E-5 T 23-10-2018 STK_14370 70dd6bc89af32514c1cac82c99b7eca8 465 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 12 78 3.4E-13 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 STK_14370 70dd6bc89af32514c1cac82c99b7eca8 465 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 344 353 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 STK_14370 70dd6bc89af32514c1cac82c99b7eca8 465 PIRSF PIRSF039114 1 465 2.1E-237 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 STK_14370 70dd6bc89af32514c1cac82c99b7eca8 465 TIGRFAM TIGR01041 ATP_syn_B_arch: ATP synthase archaeal, B subunit 8 464 5.7E-259 T 23-10-2018 IPR005724 ATPase, A1 complex, beta subunit GO:0015986|GO:0033178|GO:0046933 STK_14370 70dd6bc89af32514c1cac82c99b7eca8 465 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 6 462 60.294 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 STK_14370 70dd6bc89af32514c1cac82c99b7eca8 465 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 135 353 5.4E-65 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 STK_14370 70dd6bc89af32514c1cac82c99b7eca8 465 Gene3D G3DSA:3.40.50.12240 2 462 2.7E-177 T 23-10-2018 STK_14370 70dd6bc89af32514c1cac82c99b7eca8 465 SUPERFAMILY SSF52540 82 358 5.84E-84 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_05840 a5b8bba04f0d1da015ed50a6148b6226 215 Pfam PF00578 AhpC/TSA family 7 134 3.9E-28 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 STK_05840 a5b8bba04f0d1da015ed50a6148b6226 215 PIRSF PIRSF000239 1 209 1.3E-64 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 STK_05840 a5b8bba04f0d1da015ed50a6148b6226 215 Hamap MF_00401 Peroxiredoxin. 2 206 44.343 T 23-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 STK_05840 a5b8bba04f0d1da015ed50a6148b6226 215 Gene3D G3DSA:3.30.1020.20 142 213 3.1E-13 T 23-10-2018 STK_05840 a5b8bba04f0d1da015ed50a6148b6226 215 SUPERFAMILY SSF52833 1 206 2.35E-61 T 23-10-2018 IPR036249 Thioredoxin-like superfamily STK_05840 a5b8bba04f0d1da015ed50a6148b6226 215 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 161 188 1.6E-9 T 23-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 STK_05840 a5b8bba04f0d1da015ed50a6148b6226 215 Gene3D G3DSA:3.40.30.10 1 141 3.8E-40 T 23-10-2018 STK_00550 4f47ee2638d0e79eb30c10dbfdf2b603 350 Pfam PF01609 Transposase DDE domain 149 290 3.1E-11 T 23-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 STK_00550 4f47ee2638d0e79eb30c10dbfdf2b603 350 SUPERFAMILY SSF53098 168 305 4.63E-5 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily STK_12480 d52010a43653a3d3477861579ba4f1d7 366 SUPERFAMILY SSF111331 3 164 1.44E-7 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily STK_12480 d52010a43653a3d3477861579ba4f1d7 366 Pfam PF01513 ATP-NAD kinase 4 353 1.8E-75 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 STK_12480 d52010a43653a3d3477861579ba4f1d7 366 PIRSF PIRSF016907 1 356 6.1E-149 T 23-10-2018 IPR011386 Putative ATP-NAD kinase STK_12090 1fc3be815d9dc005bf367a1beb7aa17f 142 SUPERFAMILY SSF51306 23 90 5.75E-7 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily STK_12090 1fc3be815d9dc005bf367a1beb7aa17f 142 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 1 141 2.2E-40 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 STK_11080 bae3afdeca625fd173a4564e7394eeaf 373 SUPERFAMILY SSF54826 2 131 1.26E-26 T 23-10-2018 STK_11080 bae3afdeca625fd173a4564e7394eeaf 373 Pfam PF13378 Enolase C-terminal domain-like 153 363 1.1E-61 T 23-10-2018 IPR029065 Enolase C-terminal domain-like STK_11080 bae3afdeca625fd173a4564e7394eeaf 373 Gene3D G3DSA:3.30.390.10 2 364 9.3E-109 T 23-10-2018 IPR029017 Enolase-like, N-terminal STK_11080 bae3afdeca625fd173a4564e7394eeaf 373 SUPERFAMILY SSF51604 116 371 6.42E-73 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily STK_11080 bae3afdeca625fd173a4564e7394eeaf 373 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 31 128 1.0E-20 T 23-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain STK_11080 bae3afdeca625fd173a4564e7394eeaf 373 SMART SM00922 149 246 3.0E-24 T 23-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal STK_11080 bae3afdeca625fd173a4564e7394eeaf 373 Gene3D G3DSA:3.20.20.120 121 362 9.3E-109 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily STK_06460 f72b3d5df76b97803df586e64e08d6cb 259 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 147 249 5.1E-31 T 23-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 STK_06460 f72b3d5df76b97803df586e64e08d6cb 259 PIRSF PIRSF000193 1 254 2.1E-66 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 STK_06460 f72b3d5df76b97803df586e64e08d6cb 259 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 92 1.4E-19 T 23-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal STK_06460 f72b3d5df76b97803df586e64e08d6cb 259 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 249 6.4E-77 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 STK_06460 f72b3d5df76b97803df586e64e08d6cb 259 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 251 24.541 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 STK_06460 f72b3d5df76b97803df586e64e08d6cb 259 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 207 229 - T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 STK_06460 f72b3d5df76b97803df586e64e08d6cb 259 Gene3D G3DSA:3.40.50.720 1 149 2.2E-41 T 23-10-2018 STK_06460 f72b3d5df76b97803df586e64e08d6cb 259 SUPERFAMILY SSF48179 146 255 3.06E-31 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 STK_06460 f72b3d5df76b97803df586e64e08d6cb 259 SUPERFAMILY SSF51735 1 147 5.2E-29 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_06460 f72b3d5df76b97803df586e64e08d6cb 259 Gene3D G3DSA:1.10.3730.10 150 253 1.8E-31 T 23-10-2018 STK_11030 e50165abc78f5f41a7b9ef2197a93b90 528 SUPERFAMILY SSF53850 92 482 8.45E-63 T 23-10-2018 STK_11030 e50165abc78f5f41a7b9ef2197a93b90 528 Gene3D G3DSA:3.40.190.10 205 471 3.5E-66 T 23-10-2018 STK_11030 e50165abc78f5f41a7b9ef2197a93b90 528 Pfam PF13416 Bacterial extracellular solute-binding protein 113 412 8.6E-21 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein STK_11030 e50165abc78f5f41a7b9ef2197a93b90 528 Gene3D G3DSA:3.40.190.10 104 446 3.5E-66 T 23-10-2018 STK_22950 f627b40a7d01c04fa6a291538617cb52 458 Gene3D G3DSA:1.10.45.10 401 440 2.6E-7 T 23-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 STK_22950 f627b40a7d01c04fa6a291538617cb52 458 Pfam PF01565 FAD binding domain 35 170 3.8E-28 T 23-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 STK_22950 f627b40a7d01c04fa6a291538617cb52 458 SUPERFAMILY SSF56176 2 204 1.87E-47 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 STK_22950 f627b40a7d01c04fa6a291538617cb52 458 Pfam PF02913 FAD linked oxidases, C-terminal domain 206 439 9.7E-53 T 23-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 STK_22950 f627b40a7d01c04fa6a291538617cb52 458 SUPERFAMILY SSF55103 207 441 1.46E-57 T 23-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 STK_22950 f627b40a7d01c04fa6a291538617cb52 458 Gene3D G3DSA:3.30.70.2740 319 400 3.9E-6 T 23-10-2018 STK_22950 f627b40a7d01c04fa6a291538617cb52 458 Gene3D G3DSA:3.30.465.40 1 223 2.3E-41 T 23-10-2018 STK_03740 704645f74ab0d146990e1181480bc115 1233 SUPERFAMILY SSF56712 608 1231 3.79E-132 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain STK_03740 704645f74ab0d146990e1181480bc115 1233 Pfam PF01131 DNA topoisomerase 790 1222 7.3E-77 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 STK_03740 704645f74ab0d146990e1181480bc115 1233 Pfam PF00270 DEAD/DEAH box helicase 89 279 2.0E-10 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 STK_03740 704645f74ab0d146990e1181480bc115 1233 SMART SM00487 81 313 2.9E-18 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain STK_03740 704645f74ab0d146990e1181480bc115 1233 SMART SM00493 610 764 1.6E-32 T 23-10-2018 IPR006171 TOPRIM domain STK_03740 704645f74ab0d146990e1181480bc115 1233 SMART SM00436 765 867 1.3E-45 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 STK_03740 704645f74ab0d146990e1181480bc115 1233 Gene3D G3DSA:1.10.460.10 793 1226 6.2E-130 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 STK_03740 704645f74ab0d146990e1181480bc115 1233 Gene3D G3DSA:2.60.510.20 859 1130 6.2E-130 T 23-10-2018 STK_03740 704645f74ab0d146990e1181480bc115 1233 SUPERFAMILY SSF52540 306 589 6.84E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_03740 704645f74ab0d146990e1181480bc115 1233 SMART SM00437 900 1185 4.3E-81 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 STK_03740 704645f74ab0d146990e1181480bc115 1233 TIGRFAM TIGR01054 rgy: reverse gyrase 9 1232 0.0 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 STK_03740 704645f74ab0d146990e1181480bc115 1233 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1026 1042 5.7E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 STK_03740 704645f74ab0d146990e1181480bc115 1233 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1146 1160 5.7E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 STK_03740 704645f74ab0d146990e1181480bc115 1233 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 837 855 5.7E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 STK_03740 704645f74ab0d146990e1181480bc115 1233 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 738 751 5.7E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 STK_03740 704645f74ab0d146990e1181480bc115 1233 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 942 951 5.7E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 STK_03740 704645f74ab0d146990e1181480bc115 1233 Pfam PF01751 Toprim domain 611 774 3.3E-26 T 23-10-2018 IPR006171 TOPRIM domain STK_03740 704645f74ab0d146990e1181480bc115 1233 SUPERFAMILY SSF52540 31 282 8.15E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_03740 704645f74ab0d146990e1181480bc115 1233 Gene3D G3DSA:3.40.50.300 64 294 3.7E-62 T 23-10-2018 STK_03740 704645f74ab0d146990e1181480bc115 1233 Gene3D G3DSA:3.40.50.140 600 788 2.5E-32 T 23-10-2018 STK_03740 704645f74ab0d146990e1181480bc115 1233 Hamap MF_01125 Reverse gyrase [rgy]. 4 1233 66.946 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 STK_03740 704645f74ab0d146990e1181480bc115 1233 Gene3D G3DSA:1.10.290.10 910 1037 6.2E-130 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 STK_03740 704645f74ab0d146990e1181480bc115 1233 SMART SM00382 98 305 0.0024 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_03740 704645f74ab0d146990e1181480bc115 1233 Gene3D G3DSA:3.40.50.300 295 499 2.5E-26 T 23-10-2018 STK_03740 704645f74ab0d146990e1181480bc115 1233 Gene3D G3DSA:3.40.50.300 501 599 2.0E-11 T 23-10-2018 STK_12750 e648b2252245c1c07ddb132ed1f8ac35 175 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 2 70 1.7E-22 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 STK_12750 e648b2252245c1c07ddb132ed1f8ac35 175 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 81 160 8.5E-30 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 STK_12750 e648b2252245c1c07ddb132ed1f8ac35 175 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 19 68 - T 23-10-2018 IPR030491 TATA-box binding protein, conserved site STK_12750 e648b2252245c1c07ddb132ed1f8ac35 175 Gene3D G3DSA:3.30.310.10 80 161 4.8E-33 T 23-10-2018 IPR012295 TBP domain superfamily STK_12750 e648b2252245c1c07ddb132ed1f8ac35 175 PRINTS PR00686 Transcription initiation factor TFIID signature 16 35 2.4E-38 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 STK_12750 e648b2252245c1c07ddb132ed1f8ac35 175 PRINTS PR00686 Transcription initiation factor TFIID signature 35 53 2.4E-38 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 STK_12750 e648b2252245c1c07ddb132ed1f8ac35 175 PRINTS PR00686 Transcription initiation factor TFIID signature 125 141 2.4E-38 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 STK_12750 e648b2252245c1c07ddb132ed1f8ac35 175 PRINTS PR00686 Transcription initiation factor TFIID signature 83 99 2.4E-38 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 STK_12750 e648b2252245c1c07ddb132ed1f8ac35 175 PRINTS PR00686 Transcription initiation factor TFIID signature 106 121 2.4E-38 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 STK_12750 e648b2252245c1c07ddb132ed1f8ac35 175 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 110 159 - T 23-10-2018 IPR030491 TATA-box binding protein, conserved site STK_12750 e648b2252245c1c07ddb132ed1f8ac35 175 Hamap MF_00408 TATA-box-binding protein [tbp]. 1 165 32.719 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 STK_12750 e648b2252245c1c07ddb132ed1f8ac35 175 Gene3D G3DSA:3.30.310.10 1 79 4.7E-32 T 23-10-2018 IPR012295 TBP domain superfamily STK_12750 e648b2252245c1c07ddb132ed1f8ac35 175 SUPERFAMILY SSF55945 76 171 2.67E-31 T 23-10-2018 STK_12750 e648b2252245c1c07ddb132ed1f8ac35 175 SUPERFAMILY SSF55945 1 74 4.55E-24 T 23-10-2018 STK_20870 591d7e46574878540cd61ab68511d851 233 Pfam PF01904 Protein of unknown function DUF72 14 218 5.6E-24 T 23-10-2018 IPR002763 Protein of unknown function DUF72 STK_20870 591d7e46574878540cd61ab68511d851 233 Gene3D G3DSA:3.20.20.410 1 233 1.2E-31 T 23-10-2018 IPR036520 UPF0759 superfamily STK_20870 591d7e46574878540cd61ab68511d851 233 SUPERFAMILY SSF117396 2 232 1.7E-36 T 23-10-2018 IPR036520 UPF0759 superfamily STK_10430 73b6574ac999e3008c523cfd8d5fe0a4 149 Gene3D G3DSA:1.10.10.10 1 110 1.1E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_10430 73b6574ac999e3008c523cfd8d5fe0a4 149 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 16 71 1.5E-10 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal STK_10430 73b6574ac999e3008c523cfd8d5fe0a4 149 SUPERFAMILY SSF46785 9 114 4.01E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_22100 c1d0052c8af00ad0770229a50bf6150f 152 SUPERFAMILY SSF46785 15 104 1.97E-25 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_22100 c1d0052c8af00ad0770229a50bf6150f 152 Pfam PF03551 Transcriptional regulator PadR-like family 19 87 7.0E-17 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal STK_22100 c1d0052c8af00ad0770229a50bf6150f 152 Gene3D G3DSA:1.10.10.10 1 112 3.7E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_24590 ab15cea90d5544e47f7987f910c0766e 337 SMART SM00487 13 200 1.1E-53 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain STK_24590 ab15cea90d5544e47f7987f910c0766e 337 SUPERFAMILY SSF52540 57 323 7.39E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_24590 ab15cea90d5544e47f7987f910c0766e 337 Gene3D G3DSA:3.40.50.300 1 191 2.7E-63 T 23-10-2018 STK_24590 ab15cea90d5544e47f7987f910c0766e 337 SMART SM00490 231 311 1.5E-25 T 23-10-2018 IPR001650 Helicase, C-terminal STK_24590 ab15cea90d5544e47f7987f910c0766e 337 Pfam PF00271 Helicase conserved C-terminal domain 215 311 3.3E-27 T 23-10-2018 IPR001650 Helicase, C-terminal STK_24590 ab15cea90d5544e47f7987f910c0766e 337 Pfam PF00270 DEAD/DEAH box helicase 18 176 8.6E-44 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 STK_24590 ab15cea90d5544e47f7987f910c0766e 337 Gene3D G3DSA:3.40.50.300 192 337 1.4E-47 T 23-10-2018 STK_05130 58bd789a6fe433c976cf820f2500bcb8 256 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 182 193 - T 23-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 STK_05130 58bd789a6fe433c976cf820f2500bcb8 256 Gene3D G3DSA:1.10.510.10 150 256 3.4E-33 T 23-10-2018 STK_05130 58bd789a6fe433c976cf820f2500bcb8 256 SMART SM00090 14 249 2.0E-85 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 STK_05130 58bd789a6fe433c976cf820f2500bcb8 256 Pfam PF01163 RIO1 family 56 242 6.6E-64 T 23-10-2018 STK_05130 58bd789a6fe433c976cf820f2500bcb8 256 SUPERFAMILY SSF56112 36 245 8.54E-30 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily STK_05130 58bd789a6fe433c976cf820f2500bcb8 256 Gene3D G3DSA:3.30.200.20 42 144 1.4E-12 T 23-10-2018 STK_24070 6c48f660bb30706ff8b461bc576791bf 354 Gene3D G3DSA:1.20.1250.20 182 353 2.0E-9 T 23-10-2018 STK_24070 6c48f660bb30706ff8b461bc576791bf 354 SUPERFAMILY SSF103473 6 351 4.84E-31 T 23-10-2018 IPR036259 MFS transporter superfamily STK_24070 6c48f660bb30706ff8b461bc576791bf 354 Pfam PF07690 Major Facilitator Superfamily 6 266 2.5E-18 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_24070 6c48f660bb30706ff8b461bc576791bf 354 Gene3D G3DSA:1.20.1250.20 5 181 1.9E-16 T 23-10-2018 STK_10920 0023c45f4d520d15fd238409f858fafd 205 ProSitePatterns PS00397 Site-specific recombinases active site. 62 70 - T 23-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 STK_10920 0023c45f4d520d15fd238409f858fafd 205 SUPERFAMILY SSF53041 58 189 1.57E-23 T 23-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 STK_10920 0023c45f4d520d15fd238409f858fafd 205 SMART SM00857 59 201 4.9E-22 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 STK_10920 0023c45f4d520d15fd238409f858fafd 205 SUPERFAMILY SSF46955 3 50 3.3E-8 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily STK_10920 0023c45f4d520d15fd238409f858fafd 205 Gene3D G3DSA:1.10.1660.10 2 55 4.1E-6 T 23-10-2018 STK_10920 0023c45f4d520d15fd238409f858fafd 205 Pfam PF00239 Resolvase, N terminal domain 59 192 4.1E-26 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 STK_10920 0023c45f4d520d15fd238409f858fafd 205 Pfam PF12728 Helix-turn-helix domain 4 51 1.1E-14 T 23-10-2018 STK_10920 0023c45f4d520d15fd238409f858fafd 205 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 50 8.6E-10 T 23-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 STK_10920 0023c45f4d520d15fd238409f858fafd 205 Gene3D G3DSA:3.40.50.1390 56 157 1.4E-25 T 23-10-2018 STK_16140 331bcc1bb030b0acc9b258321ba2fd7c 481 PIRSF PIRSF019435 1 476 9.1E-172 T 23-10-2018 IPR008508 Protein of unknown function DUF790, endonuclease-like STK_16140 331bcc1bb030b0acc9b258321ba2fd7c 481 Pfam PF05626 Protein of unknown function (DUF790) 2 368 1.1E-116 T 23-10-2018 IPR008508 Protein of unknown function DUF790, endonuclease-like STK_04220 8cf1734515daa27300cc8f00a4d3d57a 138 ProSitePatterns PS00049 Ribosomal protein L14 signature. 77 103 - T 23-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04220 8cf1734515daa27300cc8f00a4d3d57a 138 SUPERFAMILY SSF50193 11 138 1.19E-45 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 STK_04220 8cf1734515daa27300cc8f00a4d3d57a 138 SMART SM01374 17 138 1.0E-62 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 STK_04220 8cf1734515daa27300cc8f00a4d3d57a 138 TIGRFAM TIGR03673 uL14_arch: 50S ribosomal protein uL14 10 138 1.9E-62 T 23-10-2018 IPR019971 Ribosomal protein L14P, archaeal STK_04220 8cf1734515daa27300cc8f00a4d3d57a 138 Pfam PF00238 Ribosomal protein L14p/L23e 19 138 1.5E-36 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 STK_04220 8cf1734515daa27300cc8f00a4d3d57a 138 Gene3D G3DSA:2.40.150.20 3 138 6.0E-51 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 STK_04220 8cf1734515daa27300cc8f00a4d3d57a 138 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 17 138 20.511 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 STK_05160 2c0a48c7e9fab98a8c47804861889823 139 Hamap MF_00232 Translation initiation factor 2 subunit beta [eif2b]. 5 139 29.041 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 STK_05160 2c0a48c7e9fab98a8c47804861889823 139 Pfam PF01873 Domain found in IF2B/IF5 28 133 2.8E-33 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 STK_05160 2c0a48c7e9fab98a8c47804861889823 139 SUPERFAMILY SSF75689 103 138 7.06E-11 T 23-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 STK_05160 2c0a48c7e9fab98a8c47804861889823 139 Gene3D G3DSA:3.30.70.3150 34 106 3.7E-29 T 23-10-2018 STK_05160 2c0a48c7e9fab98a8c47804861889823 139 SUPERFAMILY SSF100966 6 106 3.14E-26 T 23-10-2018 IPR016189 Translation initiation factor IF2/IF5, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 STK_05160 2c0a48c7e9fab98a8c47804861889823 139 SMART SM00653 25 133 3.5E-48 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 STK_01480 b3aff87711a8481a5e54a36f0e564243 108 Pfam PF02635 DsrE/DsrF-like family 23 106 6.5E-8 T 23-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein STK_01480 b3aff87711a8481a5e54a36f0e564243 108 Gene3D G3DSA:3.40.1260.10 1 108 4.1E-37 T 23-10-2018 IPR027396 DsrEFH-like STK_01480 b3aff87711a8481a5e54a36f0e564243 108 SUPERFAMILY SSF75169 1 106 1.91E-26 T 23-10-2018 IPR027396 DsrEFH-like STK_23220 3e829f5d21f775e57d91a66b95ef6274 308 PIRSF PIRSF004944 1 307 4.8E-129 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase STK_23220 3e829f5d21f775e57d91a66b95ef6274 308 SUPERFAMILY SSF56281 1 264 1.57E-24 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_23220 3e829f5d21f775e57d91a66b95ef6274 308 Hamap MF_01406 UPF0282 protein . 1 287 39.583 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase STK_23220 3e829f5d21f775e57d91a66b95ef6274 308 Pfam PF00753 Metallo-beta-lactamase superfamily 15 78 1.0E-7 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_23220 3e829f5d21f775e57d91a66b95ef6274 308 Gene3D G3DSA:3.60.15.10 9 264 8.2E-16 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_11380 59303fcc46aa375ff0854b8d8dee6ef1 328 Gene3D G3DSA:2.130.10.10 13 271 2.1E-9 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 STK_11380 59303fcc46aa375ff0854b8d8dee6ef1 328 SUPERFAMILY SSF50969 11 307 8.63E-18 T 23-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like STK_04340 4473b6cfcc69ae49b90bf00b9cfd9bf7 196 Pfam PF04289 Protein of unknown function (DUF447) 18 187 3.2E-41 T 23-10-2018 IPR007386 Protein of unknown function DUF447 STK_04340 4473b6cfcc69ae49b90bf00b9cfd9bf7 196 SUPERFAMILY SSF50475 10 188 4.45E-35 T 23-10-2018 STK_04340 4473b6cfcc69ae49b90bf00b9cfd9bf7 196 PIRSF PIRSF018747 6 111 1.0E-5 T 23-10-2018 IPR016733 Uncharacterised conserved protein UCP018747 STK_04340 4473b6cfcc69ae49b90bf00b9cfd9bf7 196 PIRSF PIRSF018747 120 192 39.0 T 23-10-2018 IPR016733 Uncharacterised conserved protein UCP018747 STK_04340 4473b6cfcc69ae49b90bf00b9cfd9bf7 196 Gene3D G3DSA:1.20.58.290 120 188 1.6E-5 T 23-10-2018 STK_04340 4473b6cfcc69ae49b90bf00b9cfd9bf7 196 Gene3D G3DSA:2.30.110.10 10 110 8.6E-20 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 STK_18710 624e4c3de4103b78d8bbce71a6e48fc3 230 Pfam PF13183 4Fe-4S dicluster domain 61 123 7.9E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_18710 624e4c3de4103b78d8bbce71a6e48fc3 230 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 109 120 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_18710 624e4c3de4103b78d8bbce71a6e48fc3 230 Gene3D G3DSA:1.10.1060.10 28 141 8.5E-11 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 STK_18710 624e4c3de4103b78d8bbce71a6e48fc3 230 SUPERFAMILY SSF46548 58 140 1.22E-15 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 STK_05140 e325216543e5352c3ac509d0a132af96 397 Gene3D G3DSA:3.40.47.10 128 391 4.4E-137 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_05140 e325216543e5352c3ac509d0a132af96 397 ProSitePatterns PS00737 Thiolases signature 2. 340 356 - T 23-10-2018 IPR020613 Thiolase, conserved site GO:0016747 STK_05140 e325216543e5352c3ac509d0a132af96 397 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 8 392 2.7E-133 T 23-10-2018 IPR002155 Thiolase GO:0016747 STK_05140 e325216543e5352c3ac509d0a132af96 397 PIRSF PIRSF000429 1 395 1.7E-118 T 23-10-2018 IPR002155 Thiolase GO:0016747 STK_05140 e325216543e5352c3ac509d0a132af96 397 SUPERFAMILY SSF53901 5 271 4.38E-80 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_05140 e325216543e5352c3ac509d0a132af96 397 Gene3D G3DSA:3.40.47.10 7 277 4.4E-137 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_05140 e325216543e5352c3ac509d0a132af96 397 SUPERFAMILY SSF53901 272 393 7.4E-35 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_05140 e325216543e5352c3ac509d0a132af96 397 Pfam PF02803 Thiolase, C-terminal domain 272 392 1.1E-35 T 23-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 STK_05140 e325216543e5352c3ac509d0a132af96 397 Pfam PF00108 Thiolase, N-terminal domain 7 263 1.7E-86 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 STK_21625 0a43cdbad5653a980c6d01ff600826e9 93 Gene3D G3DSA:3.30.1360.20 2 93 4.2E-33 T 23-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 STK_21625 0a43cdbad5653a980c6d01ff600826e9 93 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 3 91 7.5E-32 T 23-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 STK_21625 0a43cdbad5653a980c6d01ff600826e9 93 SUPERFAMILY SSF55248 3 92 6.54E-33 T 23-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 STK_21625 0a43cdbad5653a980c6d01ff600826e9 93 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 1 92 24.499 T 23-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 STK_04057 a57ba9fe92c960e03ae3c8e4336c2477 177 Gene3D G3DSA:3.40.390.10 3 176 9.0E-47 T 23-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 STK_04057 a57ba9fe92c960e03ae3c8e4336c2477 177 Pfam PF07998 Peptidase family M54 12 171 8.6E-38 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 STK_04057 a57ba9fe92c960e03ae3c8e4336c2477 177 PIRSF PIRSF005785 2 177 8.6E-54 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 STK_04057 a57ba9fe92c960e03ae3c8e4336c2477 177 SUPERFAMILY SSF55486 17 167 4.81E-16 T 23-10-2018 STK_04057 a57ba9fe92c960e03ae3c8e4336c2477 177 Hamap MF_01842 Archaemetzincin [amzA]. 2 172 33.144 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 STK_12990 cef1647c88b7b5f3ae782dc467b1b2a0 265 SUPERFAMILY SSF51735 6 261 3.14E-63 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_12990 cef1647c88b7b5f3ae782dc467b1b2a0 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.0E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_12990 cef1647c88b7b5f3ae782dc467b1b2a0 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 5.0E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_12990 cef1647c88b7b5f3ae782dc467b1b2a0 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 5.0E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_12990 cef1647c88b7b5f3ae782dc467b1b2a0 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 5.0E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_12990 cef1647c88b7b5f3ae782dc467b1b2a0 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 5.0E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_12990 cef1647c88b7b5f3ae782dc467b1b2a0 265 Gene3D G3DSA:3.40.50.720 2 264 1.3E-58 T 23-10-2018 STK_12990 cef1647c88b7b5f3ae782dc467b1b2a0 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 261 1.7E-42 T 23-10-2018 STK_24850 dc360b755b7e33abba4d4490bc834a7d 409 Gene3D G3DSA:3.50.50.60 4 332 3.9E-111 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_24850 dc360b755b7e33abba4d4490bc834a7d 409 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 191 324 3.4E-8 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 STK_24850 dc360b755b7e33abba4d4490bc834a7d 409 SUPERFAMILY SSF51905 3 334 5.02E-29 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_24850 dc360b755b7e33abba4d4490bc834a7d 409 Gene3D G3DSA:3.50.50.60 115 276 3.9E-111 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_24850 dc360b755b7e33abba4d4490bc834a7d 409 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 129 6.4E-14 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 STK_24850 dc360b755b7e33abba4d4490bc834a7d 409 SUPERFAMILY SSF51905 120 267 1.94E-10 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_03040 f8466cd61e241ea6080771383d8efa91 178 ProDom PD016744 UPF0215 ST0304 TK2033 MA4269 PAE0952 SSO0256 NEQ431 MK0057 PTO0905 TV0037 54 164 2.0E-59 T 23-10-2018 IPR002802 Protein of unknown function DUF99 STK_03040 f8466cd61e241ea6080771383d8efa91 178 Hamap MF_00582 UPF0215 protein . 1 170 27.064 T 23-10-2018 IPR002802 Protein of unknown function DUF99 STK_03040 f8466cd61e241ea6080771383d8efa91 178 Gene3D G3DSA:3.30.2170.10 2 171 1.3E-20 T 23-10-2018 STK_03040 f8466cd61e241ea6080771383d8efa91 178 Pfam PF01949 Protein of unknown function DUF99 3 168 3.1E-23 T 23-10-2018 IPR002802 Protein of unknown function DUF99 STK_03040 f8466cd61e241ea6080771383d8efa91 178 PIRSF PIRSF006380 1 177 8.7E-56 T 23-10-2018 IPR002802 Protein of unknown function DUF99 STK_16070 d1b4037c7fc4088d6d448fa8798e5b9a 513 Pfam PF13520 Amino acid permease 22 479 7.7E-23 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_16070 d1b4037c7fc4088d6d448fa8798e5b9a 513 PIRSF PIRSF006060 1 512 9.5E-40 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_16070 d1b4037c7fc4088d6d448fa8798e5b9a 513 Gene3D G3DSA:1.20.1740.10 16 500 4.9E-12 T 23-10-2018 STK_15840 1f02e142724f4d0dac05736d24d03c61 227 TIGRFAM TIGR01884 cas_HTH: CRISPR locus-related DNA-binding protein 7 210 9.1E-66 T 23-10-2018 IPR010163 CRISPR locus-related putative DNA-binding protein Csa3 STK_15840 1f02e142724f4d0dac05736d24d03c61 227 Gene3D G3DSA:1.10.10.10 130 227 2.0E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_15840 1f02e142724f4d0dac05736d24d03c61 227 Pfam PF01022 Bacterial regulatory protein, arsR family 153 195 1.1E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 STK_15840 1f02e142724f4d0dac05736d24d03c61 227 SUPERFAMILY SSF46785 151 226 2.54E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_22170 81264ca92a2f3ec7cd104e859958bc00 168 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 37 158 2.8E-43 T 23-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_22170 81264ca92a2f3ec7cd104e859958bc00 168 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 95 147 3.0E-26 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_22170 81264ca92a2f3ec7cd104e859958bc00 168 Gene3D G3DSA:3.30.460.80 1 138 3.6E-36 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_22170 81264ca92a2f3ec7cd104e859958bc00 168 SUPERFAMILY SSF143243 27 157 3.66E-43 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_22170 81264ca92a2f3ec7cd104e859958bc00 168 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 37 159 1.5E-36 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_18440 e686532185c833679f387cac1428c609 113 PIRSF PIRSF006821 1 112 5.5E-58 T 23-10-2018 IPR018685 Protein of unknown function DUF2173 STK_18440 e686532185c833679f387cac1428c609 113 Pfam PF09941 Uncharacterized conserved protein (DUF2173) 6 109 2.6E-40 T 23-10-2018 IPR018685 Protein of unknown function DUF2173 STK_13740 433e5af9f874cff4dcf28e9f78fb01d8 115 Hamap MF_00026 DNA-binding protein . 7 109 16.563 T 23-10-2018 IPR022889 DNA-binding protein, archaeal STK_13740 433e5af9f874cff4dcf28e9f78fb01d8 115 Pfam PF01984 Double-stranded DNA-binding domain 11 111 7.0E-27 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 STK_13740 433e5af9f874cff4dcf28e9f78fb01d8 115 Gene3D G3DSA:1.10.8.140 30 110 3.1E-28 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 STK_13740 433e5af9f874cff4dcf28e9f78fb01d8 115 PIRSF PIRSF015730 3 115 3.3E-35 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 STK_13740 433e5af9f874cff4dcf28e9f78fb01d8 115 SUPERFAMILY SSF46950 13 108 3.53E-28 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 STK_01030 cac9687e16ac88f69389f7caf4b56ed8 815 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 26 466 2.7E-117 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01030 cac9687e16ac88f69389f7caf4b56ed8 815 Gene3D G3DSA:1.20.120.80 618 798 3.4E-35 T 23-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01030 cac9687e16ac88f69389f7caf4b56ed8 815 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 242 297 - T 23-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01030 cac9687e16ac88f69389f7caf4b56ed8 815 SUPERFAMILY SSF81452 571 797 3.79E-43 T 23-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01030 cac9687e16ac88f69389f7caf4b56ed8 815 Pfam PF00510 Cytochrome c oxidase subunit III 629 797 8.8E-15 T 23-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01030 cac9687e16ac88f69389f7caf4b56ed8 815 Gene3D G3DSA:1.20.210.10 3 505 7.1E-148 T 23-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01030 cac9687e16ac88f69389f7caf4b56ed8 815 SUPERFAMILY SSF81442 19 509 5.1E-135 T 23-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01030 cac9687e16ac88f69389f7caf4b56ed8 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 311 332 4.1E-75 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01030 cac9687e16ac88f69389f7caf4b56ed8 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 162 180 4.1E-75 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01030 cac9687e16ac88f69389f7caf4b56ed8 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 61 84 4.1E-75 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01030 cac9687e16ac88f69389f7caf4b56ed8 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 129 141 4.1E-75 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01030 cac9687e16ac88f69389f7caf4b56ed8 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 287 302 4.1E-75 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01030 cac9687e16ac88f69389f7caf4b56ed8 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 240 261 4.1E-75 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01030 cac9687e16ac88f69389f7caf4b56ed8 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 17 42 4.1E-75 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01030 cac9687e16ac88f69389f7caf4b56ed8 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 374 393 4.1E-75 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01030 cac9687e16ac88f69389f7caf4b56ed8 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 189 208 4.1E-75 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01030 cac9687e16ac88f69389f7caf4b56ed8 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 346 364 4.1E-75 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01030 cac9687e16ac88f69389f7caf4b56ed8 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 88 112 4.1E-75 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01030 cac9687e16ac88f69389f7caf4b56ed8 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 423 444 4.1E-75 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_04230 044f0cf4d4555232fd677816ff1a4ece 113 PRINTS PR00973 Ribosomal protein S17 family signature 90 100 9.5E-9 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_04230 044f0cf4d4555232fd677816ff1a4ece 113 PRINTS PR00973 Ribosomal protein S17 family signature 57 80 9.5E-9 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_04230 044f0cf4d4555232fd677816ff1a4ece 113 PRINTS PR00973 Ribosomal protein S17 family signature 100 107 9.5E-9 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_04230 044f0cf4d4555232fd677816ff1a4ece 113 SUPERFAMILY SSF50249 37 111 8.57E-22 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_04230 044f0cf4d4555232fd677816ff1a4ece 113 Pfam PF00366 Ribosomal protein S17 43 110 2.9E-22 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_04230 044f0cf4d4555232fd677816ff1a4ece 113 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 40 110 1.0E-34 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_04230 044f0cf4d4555232fd677816ff1a4ece 113 TIGRFAM TIGR03630 uS17_arch: ribosomal protein uS17 11 112 1.3E-47 T 23-10-2018 IPR028333 Ribosomal protein S17, archaeal/eukaryotic Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04230 044f0cf4d4555232fd677816ff1a4ece 113 Hamap MF_01345_A 30S ribosomal protein S17 [rpsQ]. 9 113 31.71 T 23-10-2018 IPR019978 Ribosomal protein S17, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_04230 044f0cf4d4555232fd677816ff1a4ece 113 Gene3D G3DSA:2.40.50.1000 1 113 1.3E-35 T 23-10-2018 STK_15490 5e81f366a059824a39819b0ac7d65ea8 380 Pfam PF01136 Peptidase family U32 84 150 5.2E-11 T 23-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 STK_08420 fa0985535b811ac988e49c9a45c98dd5 219 ProSitePatterns PS00211 ABC transporters family signature. 109 123 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 STK_08420 fa0985535b811ac988e49c9a45c98dd5 219 SMART SM00382 24 182 1.8E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_08420 fa0985535b811ac988e49c9a45c98dd5 219 SUPERFAMILY SSF52540 1 189 1.36E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_08420 fa0985535b811ac988e49c9a45c98dd5 219 Pfam PF00005 ABC transporter 16 135 2.8E-15 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_08420 fa0985535b811ac988e49c9a45c98dd5 219 Gene3D G3DSA:3.40.50.300 1 206 2.2E-43 T 23-10-2018 STK_04200 d5fc354852eb909b82753d2ddb42e831 177 Hamap MF_01333_A 50S ribosomal protein L5 [rplE]. 7 175 41.617 T 23-10-2018 IPR022804 Ribosomal protein L5, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_04200 d5fc354852eb909b82753d2ddb42e831 177 ProSitePatterns PS00358 Ribosomal protein L5 signature. 38 54 - T 23-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04200 d5fc354852eb909b82753d2ddb42e831 177 SUPERFAMILY SSF55282 7 174 3.77E-57 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04200 d5fc354852eb909b82753d2ddb42e831 177 Pfam PF00673 ribosomal L5P family C-terminus 65 165 1.5E-26 T 23-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04200 d5fc354852eb909b82753d2ddb42e831 177 Gene3D G3DSA:3.30.1440.10 1 177 2.8E-69 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04200 d5fc354852eb909b82753d2ddb42e831 177 Pfam PF00281 Ribosomal protein L5 8 61 2.1E-21 T 23-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04200 d5fc354852eb909b82753d2ddb42e831 177 PIRSF PIRSF002161 1 174 1.1E-55 T 23-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_05135 3bc96a38fe9d92002d67078977e1e888 108 SUPERFAMILY SSF50249 3 98 1.69E-31 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_05135 3bc96a38fe9d92002d67078977e1e888 108 Hamap MF_00216 Translation initiation factor 1A [eif1a]. 6 99 28.214 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 STK_05135 3bc96a38fe9d92002d67078977e1e888 108 Gene3D G3DSA:2.40.50.140 2 106 1.7E-34 T 23-10-2018 STK_05135 3bc96a38fe9d92002d67078977e1e888 108 Pfam PF01176 Translation initiation factor 1A / IF-1 21 83 2.2E-24 T 23-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 STK_05135 3bc96a38fe9d92002d67078977e1e888 108 ProSitePatterns PS01262 Eukaryotic initiation factor 1A signature. 30 52 - T 23-10-2018 IPR018104 Translation initiation factor 1A (eIF-1A), conserved site GO:0003743|GO:0006413 STK_05135 3bc96a38fe9d92002d67078977e1e888 108 ProDom PD005579 INITIATION FACTOR TRANSLATION 1A BIOSYNTHESIS EUKARYOTIC EIF-1A AIF-1A EIF-4C 1A 41 95 3.0E-26 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 STK_05135 3bc96a38fe9d92002d67078977e1e888 108 SMART SM00652 17 99 2.3E-40 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 STK_05135 3bc96a38fe9d92002d67078977e1e888 108 TIGRFAM TIGR00523 eIF-1A: translation initiation factor eIF-1A 4 95 4.0E-35 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 STK_18230 7819e9b647c04bb75b1a9ee3fa781c32 253 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 5 242 6.0E-96 T 23-10-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 STK_18230 7819e9b647c04bb75b1a9ee3fa781c32 253 Gene3D G3DSA:3.40.1010.10 1 113 1.1E-31 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 STK_18230 7819e9b647c04bb75b1a9ee3fa781c32 253 Gene3D G3DSA:3.30.950.10 114 243 1.8E-44 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 STK_18230 7819e9b647c04bb75b1a9ee3fa781c32 253 SUPERFAMILY SSF53790 1 246 2.09E-55 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 STK_18230 7819e9b647c04bb75b1a9ee3fa781c32 253 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 207 6.7E-41 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 STK_21460 cb01b324229e93d578157239c8819360 174 SUPERFAMILY SSF53335 2 160 2.5E-22 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_21460 cb01b324229e93d578157239c8819360 174 Gene3D G3DSA:3.40.50.150 1 173 1.2E-42 T 23-10-2018 STK_21460 cb01b324229e93d578157239c8819360 174 Pfam PF05175 Methyltransferase small domain 16 95 1.8E-9 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 STK_21460 cb01b324229e93d578157239c8819360 174 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 87 93 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 STK_18920 d26dc2b999bc03ef0e141e9cbb9949aa 202 Pfam PF06508 Queuosine biosynthesis protein QueC 2 190 4.9E-29 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 STK_18920 d26dc2b999bc03ef0e141e9cbb9949aa 202 PIRSF PIRSF006293 1 202 3.3E-35 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 STK_18920 d26dc2b999bc03ef0e141e9cbb9949aa 202 Gene3D G3DSA:3.40.50.620 1 202 9.4E-41 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_18920 d26dc2b999bc03ef0e141e9cbb9949aa 202 SUPERFAMILY SSF52402 1 199 6.17E-39 T 23-10-2018 STK_00570 8ab60f1be701f945df7c5c141884d45f 306 SMART SM00849 15 214 1.1E-35 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_00570 8ab60f1be701f945df7c5c141884d45f 306 Gene3D G3DSA:3.60.15.10 1 242 1.2E-61 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_00570 8ab60f1be701f945df7c5c141884d45f 306 SUPERFAMILY SSF56281 7 292 3.01E-50 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_00570 8ab60f1be701f945df7c5c141884d45f 306 Pfam PF00753 Metallo-beta-lactamase superfamily 15 210 3.1E-24 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_02050 b9486a7a5c03d13f8c9919d66f775b1c 429 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 6 429 2.5E-153 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 STK_02050 b9486a7a5c03d13f8c9919d66f775b1c 429 Pfam PF00152 tRNA synthetases class II (D, K and N) 115 423 1.4E-93 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_02050 b9486a7a5c03d13f8c9919d66f775b1c 429 Pfam PF01336 OB-fold nucleic acid binding domain 22 95 1.3E-12 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 STK_02050 b9486a7a5c03d13f8c9919d66f775b1c 429 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 2 429 40.126 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 STK_02050 b9486a7a5c03d13f8c9919d66f775b1c 429 SUPERFAMILY SSF55681 113 424 2.17E-90 T 23-10-2018 STK_02050 b9486a7a5c03d13f8c9919d66f775b1c 429 Gene3D G3DSA:3.30.930.10 103 429 5.3E-118 T 23-10-2018 STK_02050 b9486a7a5c03d13f8c9919d66f775b1c 429 SUPERFAMILY SSF50249 2 102 8.57E-26 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_02050 b9486a7a5c03d13f8c9919d66f775b1c 429 Gene3D G3DSA:2.40.50.140 1 102 2.5E-28 T 23-10-2018 STK_02050 b9486a7a5c03d13f8c9919d66f775b1c 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 200 213 4.4E-19 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_02050 b9486a7a5c03d13f8c9919d66f775b1c 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 184 196 4.4E-19 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_02050 b9486a7a5c03d13f8c9919d66f775b1c 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 344 360 4.4E-19 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_02050 b9486a7a5c03d13f8c9919d66f775b1c 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 384 398 4.4E-19 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_17940 dc2b90789ddad50ec7e97ff5041056f2 281 SUPERFAMILY SSF52467 157 277 8.72E-42 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily STK_17940 dc2b90789ddad50ec7e97ff5041056f2 281 Gene3D G3DSA:3.40.50.1220 152 281 3.1E-50 T 23-10-2018 STK_17940 dc2b90789ddad50ec7e97ff5041056f2 281 Pfam PF01012 Electron transfer flavoprotein domain 49 130 1.3E-14 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 STK_17940 dc2b90789ddad50ec7e97ff5041056f2 281 PIRSF PIRSF000089 15 41 70.0 T 23-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 STK_17940 dc2b90789ddad50ec7e97ff5041056f2 281 PIRSF PIRSF000089 36 281 7.4E-84 T 23-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 STK_17940 dc2b90789ddad50ec7e97ff5041056f2 281 SUPERFAMILY SSF52402 49 190 1.95E-20 T 23-10-2018 STK_17940 dc2b90789ddad50ec7e97ff5041056f2 281 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 157 241 1.8E-33 T 23-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 STK_17940 dc2b90789ddad50ec7e97ff5041056f2 281 Gene3D G3DSA:3.40.50.620 1 149 2.1E-16 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_17940 dc2b90789ddad50ec7e97ff5041056f2 281 SMART SM00893 3 159 0.0098 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 STK_14520 38752fa35b0d1052daaa3e7cf30ca86f 122 SUPERFAMILY SSF56276 10 119 7.06E-37 T 23-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 STK_14520 38752fa35b0d1052daaa3e7cf30ca86f 122 Pfam PF02675 S-adenosylmethionine decarboxylase 16 118 5.7E-35 T 23-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 STK_14520 38752fa35b0d1052daaa3e7cf30ca86f 122 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 9 119 3.0E-40 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 STK_14520 38752fa35b0d1052daaa3e7cf30ca86f 122 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 8 121 28.49 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 STK_14520 38752fa35b0d1052daaa3e7cf30ca86f 122 Gene3D G3DSA:3.60.90.10 4 121 5.0E-36 T 23-10-2018 STK_04130 2c999a18506e4e7799472ff46669b73a 158 Gene3D G3DSA:1.10.15.30 61 117 3.1E-40 T 23-10-2018 IPR023106 Ribosomal protein L30, central domain, archaeal type STK_04130 2c999a18506e4e7799472ff46669b73a 158 Pfam PF00327 Ribosomal protein L30p/L7e 7 55 1.1E-14 T 23-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain STK_04130 2c999a18506e4e7799472ff46669b73a 158 TIGRFAM TIGR01309 uL30_arch: ribosomal protein uL30 6 158 9.0E-52 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 STK_04130 2c999a18506e4e7799472ff46669b73a 158 Gene3D G3DSA:3.30.1390.20 7 146 3.1E-40 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily STK_04130 2c999a18506e4e7799472ff46669b73a 158 Hamap MF_01371_A 50S ribosomal protein L30 [rpmD]. 1 158 63.221 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 STK_04130 2c999a18506e4e7799472ff46669b73a 158 SUPERFAMILY SSF55129 4 158 5.49E-43 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily STK_15030 ca0ba4a25c91fba6b38b07cf4dcae2d2 372 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 187 201 6.2E-28 T 23-10-2018 STK_15030 ca0ba4a25c91fba6b38b07cf4dcae2d2 372 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 257 273 6.2E-28 T 23-10-2018 STK_15030 ca0ba4a25c91fba6b38b07cf4dcae2d2 372 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 299 310 6.2E-28 T 23-10-2018 STK_15030 ca0ba4a25c91fba6b38b07cf4dcae2d2 372 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 226 240 6.2E-28 T 23-10-2018 STK_15030 ca0ba4a25c91fba6b38b07cf4dcae2d2 372 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 274 291 6.2E-28 T 23-10-2018 STK_15030 ca0ba4a25c91fba6b38b07cf4dcae2d2 372 Gene3D G3DSA:3.40.50.880 161 370 1.5E-52 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_15030 ca0ba4a25c91fba6b38b07cf4dcae2d2 372 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 9 372 41.724 T 23-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_15030 ca0ba4a25c91fba6b38b07cf4dcae2d2 372 SUPERFAMILY SSF52317 159 369 2.2E-50 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_15030 ca0ba4a25c91fba6b38b07cf4dcae2d2 372 SMART SM01097 9 146 9.0E-75 T 23-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_15030 ca0ba4a25c91fba6b38b07cf4dcae2d2 372 Gene3D G3DSA:3.50.30.20 9 160 8.3E-53 T 23-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_15030 ca0ba4a25c91fba6b38b07cf4dcae2d2 372 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 12 369 1.9E-117 T 23-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_15030 ca0ba4a25c91fba6b38b07cf4dcae2d2 372 SUPERFAMILY SSF52021 10 155 6.28E-48 T 23-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_15030 ca0ba4a25c91fba6b38b07cf4dcae2d2 372 Pfam PF00117 Glutamine amidotransferase class-I 189 366 1.8E-40 T 23-10-2018 IPR017926 Glutamine amidotransferase STK_15030 ca0ba4a25c91fba6b38b07cf4dcae2d2 372 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 11 145 1.6E-45 T 23-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_15030 ca0ba4a25c91fba6b38b07cf4dcae2d2 372 PRINTS PR00096 Glutamine amidotransferase superfamily signature 229 238 1.1E-9 T 23-10-2018 STK_15030 ca0ba4a25c91fba6b38b07cf4dcae2d2 372 PRINTS PR00096 Glutamine amidotransferase superfamily signature 257 268 1.1E-9 T 23-10-2018 STK_15030 ca0ba4a25c91fba6b38b07cf4dcae2d2 372 PRINTS PR00096 Glutamine amidotransferase superfamily signature 343 356 1.1E-9 T 23-10-2018 STK_06920 ddbbb14c338e76e20ebf282d18b5c16e 470 Pfam PF04055 Radical SAM superfamily 20 219 2.4E-22 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_06920 ddbbb14c338e76e20ebf282d18b5c16e 470 SMART SM00729 15 275 1.5E-49 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 STK_06920 ddbbb14c338e76e20ebf282d18b5c16e 470 Gene3D G3DSA:3.40.630.30 333 469 8.3E-8 T 23-10-2018 STK_06920 ddbbb14c338e76e20ebf282d18b5c16e 470 TIGRFAM TIGR01211 ELP3: radical SAM enzyme/protein acetyltransferase, ELP3 family 1 469 2.7E-207 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 STK_06920 ddbbb14c338e76e20ebf282d18b5c16e 470 Gene3D G3DSA:3.80.30.20 126 281 5.7E-15 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe STK_06920 ddbbb14c338e76e20ebf282d18b5c16e 470 SUPERFAMILY SSF55729 355 464 5.87E-11 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase STK_06920 ddbbb14c338e76e20ebf282d18b5c16e 470 Pfam PF00583 Acetyltransferase (GNAT) family 353 458 1.8E-8 T 23-10-2018 IPR000182 GNAT domain STK_06920 ddbbb14c338e76e20ebf282d18b5c16e 470 Pfam PF16199 Radical_SAM C-terminal domain 236 316 1.2E-27 T 23-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 STK_06920 ddbbb14c338e76e20ebf282d18b5c16e 470 SUPERFAMILY SSF102114 17 282 8.76E-34 T 23-10-2018 STK_06920 ddbbb14c338e76e20ebf282d18b5c16e 470 PIRSF PIRSF005669 1 470 3.1E-220 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 STK_15730 0400378d02c4e88eca135a5ec405d6b5 118 Pfam PF01909 Nucleotidyltransferase domain 21 97 7.4E-11 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_15730 0400378d02c4e88eca135a5ec405d6b5 118 SUPERFAMILY SSF81301 22 103 1.19E-15 T 23-10-2018 STK_15730 0400378d02c4e88eca135a5ec405d6b5 118 Gene3D G3DSA:3.30.460.10 2 112 5.4E-29 T 23-10-2018 STK_15160 8ba03abb7daf1ff92b3145b2a9acc429 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 23-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 STK_15160 8ba03abb7daf1ff92b3145b2a9acc429 257 Gene3D G3DSA:1.10.12.10 200 256 2.8E-19 T 23-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal STK_15160 8ba03abb7daf1ff92b3145b2a9acc429 257 SUPERFAMILY SSF52096 1 257 2.8E-90 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily STK_15160 8ba03abb7daf1ff92b3145b2a9acc429 257 Gene3D G3DSA:3.90.226.10 1 198 2.0E-75 T 23-10-2018 STK_15160 8ba03abb7daf1ff92b3145b2a9acc429 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 256 8.0E-71 T 23-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 STK_21130 a99883e3c919fb5d05481152b0e8d679 273 SUPERFAMILY SSF54631 133 256 3.79E-31 T 23-10-2018 STK_21130 a99883e3c919fb5d05481152b0e8d679 273 SUPERFAMILY SSF54631 9 129 1.52E-20 T 23-10-2018 STK_21130 a99883e3c919fb5d05481152b0e8d679 273 Gene3D G3DSA:3.10.580.10 132 271 1.7E-33 T 23-10-2018 STK_21130 a99883e3c919fb5d05481152b0e8d679 273 Gene3D G3DSA:3.10.580.10 4 131 4.2E-21 T 23-10-2018 STK_21130 a99883e3c919fb5d05481152b0e8d679 273 SMART SM00116 11 59 2.0 T 23-10-2018 IPR000644 CBS domain STK_21130 a99883e3c919fb5d05481152b0e8d679 273 SMART SM00116 78 126 1.2 T 23-10-2018 IPR000644 CBS domain STK_21130 a99883e3c919fb5d05481152b0e8d679 273 SMART SM00116 142 189 2.7E-8 T 23-10-2018 IPR000644 CBS domain STK_21130 a99883e3c919fb5d05481152b0e8d679 273 SMART SM00116 207 255 1.1E-7 T 23-10-2018 IPR000644 CBS domain STK_21130 a99883e3c919fb5d05481152b0e8d679 273 Pfam PF00571 CBS domain 135 185 5.9E-13 T 23-10-2018 IPR000644 CBS domain STK_21130 a99883e3c919fb5d05481152b0e8d679 273 Pfam PF00571 CBS domain 200 254 8.7E-11 T 23-10-2018 IPR000644 CBS domain STK_21130 a99883e3c919fb5d05481152b0e8d679 273 Pfam PF00571 CBS domain 71 125 1.3E-4 T 23-10-2018 IPR000644 CBS domain STK_21130 a99883e3c919fb5d05481152b0e8d679 273 Pfam PF00571 CBS domain 10 58 6.4E-5 T 23-10-2018 IPR000644 CBS domain STK_00610 5cbdbdb006a27bfda20e994e648b3991 138 SUPERFAMILY SSF54637 6 131 1.02E-26 T 23-10-2018 IPR029069 HotDog domain superfamily STK_00610 5cbdbdb006a27bfda20e994e648b3991 138 Pfam PF03061 Thioesterase superfamily 44 118 1.2E-15 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 STK_00610 5cbdbdb006a27bfda20e994e648b3991 138 Gene3D G3DSA:3.10.129.10 2 136 1.8E-29 T 23-10-2018 STK_00610 5cbdbdb006a27bfda20e994e648b3991 138 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 13 126 5.1E-19 T 23-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 STK_26370 c45232145c3cc5afe5cd4d6e64e6378e 316 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 5 269 1.7E-77 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR STK_26370 c45232145c3cc5afe5cd4d6e64e6378e 316 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 4 254 2.5E-50 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR STK_26370 c45232145c3cc5afe5cd4d6e64e6378e 316 TIGRFAM TIGR02583 DevR_archaea: CRISPR-associated protein Cas7/Csa2, subtype I-A/APERN 1 277 3.5E-94 T 23-10-2018 IPR002764 CRISPR-associated protein Cas7/Cst2/DevR, subtype I-a/Apern STK_00950 ac05f116c246036ad63b9c9e32b279b9 243 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 239 6.5E-45 T 23-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 STK_00950 ac05f116c246036ad63b9c9e32b279b9 243 SUPERFAMILY SSF52096 2 241 3.37E-59 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily STK_00950 ac05f116c246036ad63b9c9e32b279b9 243 Gene3D G3DSA:3.90.226.10 2 243 3.7E-60 T 23-10-2018 STK_08970 f7c8aa7ab65b3194b150900af44a63d5 125 SUPERFAMILY SSF88723 4 115 2.52E-12 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_08970 f7c8aa7ab65b3194b150900af44a63d5 125 Pfam PF01850 PIN domain 4 108 1.1E-9 T 23-10-2018 IPR002716 PIN domain STK_08970 f7c8aa7ab65b3194b150900af44a63d5 125 Gene3D G3DSA:3.40.50.1010 1 112 1.7E-18 T 23-10-2018 STK_19120 306d68c9a740ba834d0a6e7c2751a105 725 Pfam PF13718 GNAT acetyltransferase 2 425 532 1.1E-20 T 23-10-2018 IPR000182 GNAT domain STK_19120 306d68c9a740ba834d0a6e7c2751a105 725 Pfam PF13718 GNAT acetyltransferase 2 537 586 1.2E-6 T 23-10-2018 IPR000182 GNAT domain STK_19120 306d68c9a740ba834d0a6e7c2751a105 725 Gene3D G3DSA:3.40.630.30 387 584 2.2E-45 T 23-10-2018 STK_19120 306d68c9a740ba834d0a6e7c2751a105 725 SUPERFAMILY SSF53335 53 159 9.52E-5 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_19120 306d68c9a740ba834d0a6e7c2751a105 725 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 12 724 40.15 T 23-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 STK_19120 306d68c9a740ba834d0a6e7c2751a105 725 Gene3D G3DSA:3.40.50.12320 216 385 1.5E-24 T 23-10-2018 STK_19120 306d68c9a740ba834d0a6e7c2751a105 725 Pfam PF05127 Helicase 221 395 1.1E-44 T 23-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 STK_19120 306d68c9a740ba834d0a6e7c2751a105 725 SUPERFAMILY SSF52540 192 341 5.92E-11 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_19120 306d68c9a740ba834d0a6e7c2751a105 725 Pfam PF08351 Domain of unknown function (DUF1726) 74 158 1.0E-20 T 23-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 STK_19120 306d68c9a740ba834d0a6e7c2751a105 725 SUPERFAMILY SSF55729 501 566 6.2E-9 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase STK_12870 3d6841c846e6bd0e78023f1f456b65fe 543 SMART SM00487 155 337 3.2E-25 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain STK_12870 3d6841c846e6bd0e78023f1f456b65fe 543 SMART SM00490 421 501 1.7E-14 T 23-10-2018 IPR001650 Helicase, C-terminal STK_12870 3d6841c846e6bd0e78023f1f456b65fe 543 Gene3D G3DSA:3.40.50.300 147 322 8.7E-44 T 23-10-2018 STK_12870 3d6841c846e6bd0e78023f1f456b65fe 543 Gene3D G3DSA:3.40.50.300 323 540 2.5E-48 T 23-10-2018 STK_12870 3d6841c846e6bd0e78023f1f456b65fe 543 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 388 527 3.0E-25 T 23-10-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 STK_12870 3d6841c846e6bd0e78023f1f456b65fe 543 Pfam PF04851 Type III restriction enzyme, res subunit 158 297 7.0E-25 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 STK_12870 3d6841c846e6bd0e78023f1f456b65fe 543 SUPERFAMILY SSF52540 199 522 5.94E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_13860 a0c9c6b4b5c2f15e639eab390afc98a1 300 Pfam PF01047 MarR family 6 52 1.5E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 STK_13860 a0c9c6b4b5c2f15e639eab390afc98a1 300 PIRSF PIRSF012876 1 300 1.4E-126 T 23-10-2018 IPR014466 Predicted transcriptional regulator, AF1742 type STK_13860 a0c9c6b4b5c2f15e639eab390afc98a1 300 SUPERFAMILY SSF53850 67 287 9.19E-11 T 23-10-2018 STK_13860 a0c9c6b4b5c2f15e639eab390afc98a1 300 SUPERFAMILY SSF46785 3 54 6.11E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_13860 a0c9c6b4b5c2f15e639eab390afc98a1 300 Gene3D G3DSA:1.10.10.10 1 67 8.9E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_09260 1a62e713a5e99870026e51097799e9bf 217 Pfam PF00128 Alpha amylase, catalytic domain 121 198 1.2E-18 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 STK_09260 1a62e713a5e99870026e51097799e9bf 217 Gene3D G3DSA:3.20.20.80 97 206 2.3E-56 T 23-10-2018 STK_09260 1a62e713a5e99870026e51097799e9bf 217 SUPERFAMILY SSF81296 2 83 2.27E-15 T 23-10-2018 IPR014756 Immunoglobulin E-set STK_09260 1a62e713a5e99870026e51097799e9bf 217 SUPERFAMILY SSF51445 94 206 2.23E-44 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily STK_09260 1a62e713a5e99870026e51097799e9bf 217 Gene3D G3DSA:2.60.40.10 1 85 2.1E-22 T 23-10-2018 IPR013783 Immunoglobulin-like fold STK_01540 3bf60da62ee8a9d8be25d21b12a2150e 125 Gene3D G3DSA:3.40.50.1010 6 123 7.0E-9 T 23-10-2018 STK_01540 3bf60da62ee8a9d8be25d21b12a2150e 125 SUPERFAMILY SSF88723 6 120 7.85E-11 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_01540 3bf60da62ee8a9d8be25d21b12a2150e 125 Pfam PF01850 PIN domain 23 117 1.6E-5 T 23-10-2018 IPR002716 PIN domain STK_02900 8b9546a93ebd1236619ef51f7d8d750b 348 SUPERFAMILY SSF52440 2 106 4.32E-36 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily STK_02900 8b9546a93ebd1236619ef51f7d8d750b 348 PIRSF PIRSF004602 1 348 1.4E-144 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 STK_02900 8b9546a93ebd1236619ef51f7d8d750b 348 SUPERFAMILY SSF56059 111 348 2.69E-78 T 23-10-2018 STK_02900 8b9546a93ebd1236619ef51f7d8d750b 348 Gene3D G3DSA:3.30.1490.20 125 189 8.9E-95 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 STK_02900 8b9546a93ebd1236619ef51f7d8d750b 348 Pfam PF06849 Protein of unknown function (DUF1246) 4 128 1.7E-46 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 STK_02900 8b9546a93ebd1236619ef51f7d8d750b 348 Gene3D G3DSA:3.40.50.20 1 93 1.8E-30 T 23-10-2018 STK_02900 8b9546a93ebd1236619ef51f7d8d750b 348 Gene3D G3DSA:3.30.470.20 96 346 8.9E-95 T 23-10-2018 STK_02900 8b9546a93ebd1236619ef51f7d8d750b 348 Pfam PF06973 Domain of unknown function (DUF1297) 160 348 7.4E-82 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 STK_25710 13eff4f6c7aaa1dd5a8c82dfdac3dec5 407 Gene3D G3DSA:3.40.50.300 20 99 4.3E-5 T 23-10-2018 STK_25710 13eff4f6c7aaa1dd5a8c82dfdac3dec5 407 Pfam PF13635 Domain of unknown function (DUF4143) 218 349 3.5E-10 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 STK_25710 13eff4f6c7aaa1dd5a8c82dfdac3dec5 407 Pfam PF13173 AAA domain 40 161 1.1E-31 T 23-10-2018 STK_25710 13eff4f6c7aaa1dd5a8c82dfdac3dec5 407 SMART SM00382 38 154 0.0083 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_25710 13eff4f6c7aaa1dd5a8c82dfdac3dec5 407 SUPERFAMILY SSF52540 19 212 2.01E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_14530 a614f5471fc0a22e3918bef3208dbc57 322 PIRSF PIRSF004976 1 321 7.7E-90 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 STK_14530 a614f5471fc0a22e3918bef3208dbc57 322 Pfam PF01171 PP-loop family 49 187 5.5E-10 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 STK_14530 a614f5471fc0a22e3918bef3208dbc57 322 SUPERFAMILY SSF52402 26 244 2.65E-34 T 23-10-2018 STK_14530 a614f5471fc0a22e3918bef3208dbc57 322 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 201 311 1.4E-22 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 STK_14530 a614f5471fc0a22e3918bef3208dbc57 322 Gene3D G3DSA:3.40.50.620 1 316 2.2E-56 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_15250 609c20cb31a708709e704eec929af171 228 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 6 215 9.7E-36 T 23-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 STK_15250 609c20cb31a708709e704eec929af171 228 Pfam PF03099 Biotin/lipoate A/B protein ligase family 7 126 3.6E-14 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 STK_15250 609c20cb31a708709e704eec929af171 228 Gene3D G3DSA:3.30.930.10 1 183 2.6E-43 T 23-10-2018 STK_15250 609c20cb31a708709e704eec929af171 228 SUPERFAMILY SSF55681 2 168 6.09E-41 T 23-10-2018 STK_15320 72091e4c5317825e7809b45d2c564140 386 SUPERFAMILY SSF52518 10 253 6.56E-66 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold STK_15320 72091e4c5317825e7809b45d2c564140 386 Gene3D G3DSA:3.40.50.970 7 255 1.8E-96 T 23-10-2018 STK_15320 72091e4c5317825e7809b45d2c564140 386 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 21 243 2.6E-69 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 STK_15320 72091e4c5317825e7809b45d2c564140 386 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 266 366 3.4E-33 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II STK_15320 72091e4c5317825e7809b45d2c564140 386 SUPERFAMILY SSF52922 256 377 2.57E-31 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 STK_15320 72091e4c5317825e7809b45d2c564140 386 Gene3D G3DSA:3.40.50.920 256 385 2.0E-39 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 STK_14400 226adec3c24acf632889ed8b9868843c 483 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 100 274 7.2E-25 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_14400 226adec3c24acf632889ed8b9868843c 483 SMART SM00946 414 483 4.1E-26 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 STK_14400 226adec3c24acf632889ed8b9868843c 483 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 9 483 9.8E-174 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 STK_14400 226adec3c24acf632889ed8b9868843c 483 SUPERFAMILY SSF64586 409 483 7.85E-20 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 STK_14400 226adec3c24acf632889ed8b9868843c 483 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 1.2E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 STK_14400 226adec3c24acf632889ed8b9868843c 483 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 1.2E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 STK_14400 226adec3c24acf632889ed8b9868843c 483 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 1.2E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 STK_14400 226adec3c24acf632889ed8b9868843c 483 PRINTS PR01046 Prolyl-tRNA synthetase signature 65 83 1.2E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 STK_14400 226adec3c24acf632889ed8b9868843c 483 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 415 483 1.9E-15 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 STK_14400 226adec3c24acf632889ed8b9868843c 483 Gene3D G3DSA:3.30.110.30 410 482 4.8E-16 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 STK_14400 226adec3c24acf632889ed8b9868843c 483 Pfam PF03129 Anticodon binding domain 290 386 1.6E-21 T 23-10-2018 IPR004154 Anticodon-binding STK_14400 226adec3c24acf632889ed8b9868843c 483 SUPERFAMILY SSF55681 9 277 1.76E-81 T 23-10-2018 STK_14400 226adec3c24acf632889ed8b9868843c 483 Hamap MF_01571 Proline--tRNA ligase [proS]. 5 483 39.855 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 STK_14400 226adec3c24acf632889ed8b9868843c 483 Gene3D G3DSA:3.30.930.10 2 282 3.9E-82 T 23-10-2018 STK_14400 226adec3c24acf632889ed8b9868843c 483 SUPERFAMILY SSF52954 279 406 3.62E-31 T 23-10-2018 STK_14400 226adec3c24acf632889ed8b9868843c 483 Gene3D G3DSA:3.40.50.800 284 403 1.5E-35 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily STK_09770 4de46ea182b966e12966dc3fb747717a 326 Pfam PF00288 GHMP kinases N terminal domain 93 150 1.4E-8 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 STK_09770 4de46ea182b966e12966dc3fb747717a 326 SUPERFAMILY SSF54211 6 172 2.81E-40 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold STK_09770 4de46ea182b966e12966dc3fb747717a 326 Gene3D G3DSA:3.30.230.10 3 184 2.6E-66 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup STK_09770 4de46ea182b966e12966dc3fb747717a 326 SUPERFAMILY SSF55060 178 322 3.6E-42 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily STK_09770 4de46ea182b966e12966dc3fb747717a 326 PIRSF PIRSF015950 2 325 2.4E-108 T 23-10-2018 IPR005935 Diphosphomevalonate/phosphomevalonate decarboxylase GO:0008299|GO:0016831 Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 STK_09770 4de46ea182b966e12966dc3fb747717a 326 Gene3D G3DSA:3.30.70.890 185 325 3.1E-47 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily STK_09770 4de46ea182b966e12966dc3fb747717a 326 TIGRFAM TIGR01240 mevDPdecarb: diphosphomevalonate decarboxylase 6 303 4.7E-88 T 23-10-2018 IPR029765 Diphosphomevalonate decarboxylase GO:0004163|GO:0005829|GO:0019287 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 STK_22320 9baa66c99934a80909c59c4d80775d1e 141 SUPERFAMILY SSF46785 10 108 2.94E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_22320 9baa66c99934a80909c59c4d80775d1e 141 Gene3D G3DSA:1.10.10.10 5 66 7.1E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_22320 9baa66c99934a80909c59c4d80775d1e 141 Pfam PF01022 Bacterial regulatory protein, arsR family 15 53 4.9E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 STK_09640 b91c3ea38f944939e48acc90257f3036 240 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 61 183 1.4E-13 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 STK_09640 b91c3ea38f944939e48acc90257f3036 240 SMART SM00478 65 214 2.7E-14 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 STK_09640 b91c3ea38f944939e48acc90257f3036 240 SUPERFAMILY SSF48150 39 236 2.67E-41 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 STK_09640 b91c3ea38f944939e48acc90257f3036 240 Gene3D G3DSA:1.10.1670.10 167 240 5.9E-9 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 STK_09640 b91c3ea38f944939e48acc90257f3036 240 Gene3D G3DSA:1.10.340.30 47 159 4.9E-23 T 23-10-2018 STK_09640 b91c3ea38f944939e48acc90257f3036 240 SMART SM00525 215 234 0.0039 T 23-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 STK_09640 b91c3ea38f944939e48acc90257f3036 240 PIRSF PIRSF001435 26 240 6.5E-48 T 23-10-2018 STK_19980 2abdb9bd9b26771819fe970edeb46264 134 Pfam PF05433 Glycine zipper 2TM domain 53 94 5.5E-11 T 23-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 STK_07780 ce378c3e4b1309c337fc0e4796e1be82 701 Gene3D G3DSA:1.10.510.10 362 688 3.4E-35 T 23-10-2018 STK_07780 ce378c3e4b1309c337fc0e4796e1be82 701 Pfam PF00069 Protein kinase domain 383 685 6.5E-30 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 STK_07780 ce378c3e4b1309c337fc0e4796e1be82 701 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 388 409 - T 23-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 STK_07780 ce378c3e4b1309c337fc0e4796e1be82 701 SMART SM00220 382 691 1.0E-21 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 STK_07780 ce378c3e4b1309c337fc0e4796e1be82 701 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 522 534 - T 23-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 STK_07780 ce378c3e4b1309c337fc0e4796e1be82 701 SUPERFAMILY SSF56112 378 696 1.37E-41 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily STK_24470 17820ed3b5f11f49d3376831a521f6bb 134 ProSitePatterns PS01318 TsaA-like domain signature. 69 80 - T 23-10-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site STK_24470 17820ed3b5f11f49d3376831a521f6bb 134 Pfam PF01980 Uncharacterised protein family UPF0066 21 116 7.1E-33 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain STK_24470 17820ed3b5f11f49d3376831a521f6bb 134 SUPERFAMILY SSF118196 1 133 1.7E-42 T 23-10-2018 IPR036413 YaeB-like superfamily STK_24470 17820ed3b5f11f49d3376831a521f6bb 134 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 11 118 3.6E-30 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain STK_24470 17820ed3b5f11f49d3376831a521f6bb 134 Gene3D G3DSA:2.40.30.70 1 133 2.6E-36 T 23-10-2018 IPR036414 YaeB, N-terminal domain superfamily STK_00220 42650ec3b6799d972fc85260eb9b9ff8 184 Pfam PF01930 Domain of unknown function DUF83 5 173 1.3E-25 T 23-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 STK_00220 42650ec3b6799d972fc85260eb9b9ff8 184 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 3 174 1.5E-44 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 STK_00220 42650ec3b6799d972fc85260eb9b9ff8 184 Gene3D G3DSA:3.90.320.10 1 175 7.8E-11 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal STK_19630 614e0b925970bdf461456040cceda1b7 402 Pfam PF00534 Glycosyl transferases group 1 205 367 4.6E-24 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 STK_19630 614e0b925970bdf461456040cceda1b7 402 SUPERFAMILY SSF53756 3 397 9.94E-37 T 23-10-2018 STK_19630 614e0b925970bdf461456040cceda1b7 402 Gene3D G3DSA:3.40.50.2000 201 373 5.2E-32 T 23-10-2018 STK_22080 481efcbd5bd245b451e68144e0b8d453 260 PRINTS PR00721 Stomatin signature 30 52 1.2E-54 T 23-10-2018 IPR001972 Stomatin family GO:0016020 STK_22080 481efcbd5bd245b451e68144e0b8d453 260 PRINTS PR00721 Stomatin signature 175 196 1.2E-54 T 23-10-2018 IPR001972 Stomatin family GO:0016020 STK_22080 481efcbd5bd245b451e68144e0b8d453 260 PRINTS PR00721 Stomatin signature 200 223 1.2E-54 T 23-10-2018 IPR001972 Stomatin family GO:0016020 STK_22080 481efcbd5bd245b451e68144e0b8d453 260 PRINTS PR00721 Stomatin signature 77 98 1.2E-54 T 23-10-2018 IPR001972 Stomatin family GO:0016020 STK_22080 481efcbd5bd245b451e68144e0b8d453 260 PRINTS PR00721 Stomatin signature 132 155 1.2E-54 T 23-10-2018 IPR001972 Stomatin family GO:0016020 STK_22080 481efcbd5bd245b451e68144e0b8d453 260 PRINTS PR00721 Stomatin signature 112 129 1.2E-54 T 23-10-2018 IPR001972 Stomatin family GO:0016020 STK_22080 481efcbd5bd245b451e68144e0b8d453 260 PRINTS PR00721 Stomatin signature 156 174 1.2E-54 T 23-10-2018 IPR001972 Stomatin family GO:0016020 STK_22080 481efcbd5bd245b451e68144e0b8d453 260 Gene3D G3DSA:3.30.479.30 51 182 8.5E-47 T 23-10-2018 STK_22080 481efcbd5bd245b451e68144e0b8d453 260 SMART SM00244 23 180 9.6E-61 T 23-10-2018 IPR001107 Band 7 domain STK_22080 481efcbd5bd245b451e68144e0b8d453 260 SUPERFAMILY SSF117892 54 187 2.62E-44 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily STK_22080 481efcbd5bd245b451e68144e0b8d453 260 Pfam PF01145 SPFH domain / Band 7 family 27 196 3.9E-39 T 23-10-2018 IPR001107 Band 7 domain STK_10580 418c388ea8a312f33fcb017877f7033f 602 Gene3D G3DSA:2.170.8.10 68 381 2.7E-150 T 23-10-2018 STK_10580 418c388ea8a312f33fcb017877f7033f 602 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 22 586 33.897 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 STK_10580 418c388ea8a312f33fcb017877f7033f 602 SUPERFAMILY SSF68923 16 234 1.52E-62 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 STK_10580 418c388ea8a312f33fcb017877f7033f 602 Gene3D G3DSA:3.40.449.10 31 237 2.7E-150 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 STK_10580 418c388ea8a312f33fcb017877f7033f 602 SUPERFAMILY SSF53795 235 585 2.52E-106 T 23-10-2018 STK_10580 418c388ea8a312f33fcb017877f7033f 602 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 33 230 2.3E-55 T 23-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 STK_10580 418c388ea8a312f33fcb017877f7033f 602 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 235 585 4.7E-101 T 23-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 STK_10580 418c388ea8a312f33fcb017877f7033f 602 Gene3D G3DSA:3.90.228.20 238 584 2.7E-150 T 23-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 STK_10580 418c388ea8a312f33fcb017877f7033f 602 PIRSF PIRSF001348 9 589 2.1E-192 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 Gene3D G3DSA:3.30.390.30 318 428 5.5E-23 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 5.1E-29 T 23-10-2018 STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 164 182 5.1E-29 T 23-10-2018 STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 242 258 5.1E-29 T 23-10-2018 STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 5.1E-29 T 23-10-2018 STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 127 145 5.1E-29 T 23-10-2018 STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 Gene3D G3DSA:3.50.50.60 139 249 1.9E-81 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 305 2.8E-52 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 PIRSF PIRSF000350 1 435 6.8E-65 T 23-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 37 47 - T 23-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 Gene3D G3DSA:3.50.50.60 6 308 1.9E-81 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 164 189 1.7E-52 T 23-10-2018 STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 399 419 1.7E-52 T 23-10-2018 STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.7E-52 T 23-10-2018 STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 243 257 1.7E-52 T 23-10-2018 STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 284 291 1.7E-52 T 23-10-2018 STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 320 341 1.7E-52 T 23-10-2018 STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 51 1.7E-52 T 23-10-2018 STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 130 139 1.7E-52 T 23-10-2018 STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 SUPERFAMILY SSF55424 321 426 8.93E-23 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 324 424 1.9E-15 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 STK_18790 9a13b4ead2bbe806b0676d74ab459056 437 SUPERFAMILY SSF51905 1 338 1.42E-48 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_25007 c25d05e3f69436a7f44e6444d9db2cc8 55 SUPERFAMILY SSF47598 10 48 4.08E-5 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 STK_25007 c25d05e3f69436a7f44e6444d9db2cc8 55 Pfam PF01402 Ribbon-helix-helix protein, copG family 12 49 1.3E-10 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 STK_23240 66be2baf872dc995a1eb9bf3064056ba 329 SUPERFAMILY SSF52768 5 300 8.15E-74 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily STK_23240 66be2baf872dc995a1eb9bf3064056ba 329 Gene3D G3DSA:3.40.800.20 6 325 1.6E-71 T 23-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 STK_23240 66be2baf872dc995a1eb9bf3064056ba 329 Pfam PF00850 Histone deacetylase domain 21 279 2.4E-56 T 23-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 STK_13550 e473f5702837b7b414c2f650e9ec5858 135 Pfam PF00582 Universal stress protein family 13 135 2.8E-15 T 23-10-2018 IPR006016 UspA STK_13550 e473f5702837b7b414c2f650e9ec5858 135 PRINTS PR01438 Universal stress protein signature 95 107 1.4E-12 T 23-10-2018 IPR006015 Universal stress protein A STK_13550 e473f5702837b7b414c2f650e9ec5858 135 PRINTS PR01438 Universal stress protein signature 12 30 1.4E-12 T 23-10-2018 IPR006015 Universal stress protein A STK_13550 e473f5702837b7b414c2f650e9ec5858 135 PRINTS PR01438 Universal stress protein signature 113 135 1.4E-12 T 23-10-2018 IPR006015 Universal stress protein A STK_13550 e473f5702837b7b414c2f650e9ec5858 135 SUPERFAMILY SSF52402 12 135 1.19E-21 T 23-10-2018 STK_13550 e473f5702837b7b414c2f650e9ec5858 135 Gene3D G3DSA:3.40.50.620 9 135 1.8E-19 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_07580 0716e8ee3a4d246a48b3f575235787d8 106 Pfam PF01638 HxlR-like helix-turn-helix 15 100 4.3E-23 T 23-10-2018 IPR002577 Helix-turn-helix, HxlR type STK_07580 0716e8ee3a4d246a48b3f575235787d8 106 SMART SM00418 11 94 0.003 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 STK_07580 0716e8ee3a4d246a48b3f575235787d8 106 SUPERFAMILY SSF46785 4 103 5.91E-30 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_07580 0716e8ee3a4d246a48b3f575235787d8 106 Gene3D G3DSA:1.10.10.10 2 106 5.1E-32 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_19100 88ede7f22c88e10bcd55254f0b27a82a 241 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 239 1.5E-59 T 23-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 STK_19100 88ede7f22c88e10bcd55254f0b27a82a 241 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 239 1.4E-56 T 23-10-2018 STK_19100 88ede7f22c88e10bcd55254f0b27a82a 241 Gene3D G3DSA:3.60.10.10 1 239 1.1E-71 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily STK_19100 88ede7f22c88e10bcd55254f0b27a82a 241 SUPERFAMILY SSF56219 1 240 1.05E-57 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily STK_19100 88ede7f22c88e10bcd55254f0b27a82a 241 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 232 5.6E-15 T 23-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase STK_01470 f5b8e2602825c6897e66d70ebbb148bb 621 SMART SM00487 1 178 2.4E-10 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain STK_01470 f5b8e2602825c6897e66d70ebbb148bb 621 SMART SM00490 228 323 2.1E-24 T 23-10-2018 IPR001650 Helicase, C-terminal STK_01470 f5b8e2602825c6897e66d70ebbb148bb 621 Gene3D G3DSA:3.40.50.300 3 166 2.6E-37 T 23-10-2018 STK_01470 f5b8e2602825c6897e66d70ebbb148bb 621 SUPERFAMILY SSF158702 469 562 1.02E-9 T 23-10-2018 STK_01470 f5b8e2602825c6897e66d70ebbb148bb 621 Pfam PF00270 DEAD/DEAH box helicase 13 147 2.2E-13 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 STK_01470 f5b8e2602825c6897e66d70ebbb148bb 621 Gene3D G3DSA:1.10.3380.20 463 553 2.5E-5 T 23-10-2018 STK_01470 f5b8e2602825c6897e66d70ebbb148bb 621 Pfam PF00271 Helicase conserved C-terminal domain 212 323 2.9E-16 T 23-10-2018 IPR001650 Helicase, C-terminal STK_01470 f5b8e2602825c6897e66d70ebbb148bb 621 Gene3D G3DSA:3.40.50.300 240 349 7.6E-30 T 23-10-2018 STK_01470 f5b8e2602825c6897e66d70ebbb148bb 621 SUPERFAMILY SSF52540 15 334 1.12E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_09910 cb265f014783492217b403a951a582c9 110 Gene3D G3DSA:3.40.630.90 1 110 5.9E-30 T 23-10-2018 STK_06970 cab565ffb6e1b18215ab293084cab4b1 177 Pfam PF00881 Nitroreductase family 77 143 1.2E-9 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 STK_06970 cab565ffb6e1b18215ab293084cab4b1 177 Pfam PF00881 Nitroreductase family 9 61 1.8E-13 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 STK_06970 cab565ffb6e1b18215ab293084cab4b1 177 SUPERFAMILY SSF55469 1 169 1.15E-47 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 STK_06970 cab565ffb6e1b18215ab293084cab4b1 177 Gene3D G3DSA:3.40.109.10 1 176 1.9E-47 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 STK_07320 414359c09fd2317d0fe0ae23a888f944 598 Pfam PF00037 4Fe-4S binding domain 561 583 1.6E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_07320 414359c09fd2317d0fe0ae23a888f944 598 SUPERFAMILY SSF52922 214 302 7.18E-5 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 STK_07320 414359c09fd2317d0fe0ae23a888f944 598 Gene3D G3DSA:3.40.50.970 1 177 1.9E-50 T 23-10-2018 STK_07320 414359c09fd2317d0fe0ae23a888f944 598 SUPERFAMILY SSF52518 340 546 8.51E-28 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold STK_07320 414359c09fd2317d0fe0ae23a888f944 598 SUPERFAMILY SSF52518 1 208 7.69E-56 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold STK_07320 414359c09fd2317d0fe0ae23a888f944 598 Gene3D G3DSA:3.30.70.20 535 597 7.2E-10 T 23-10-2018 STK_07320 414359c09fd2317d0fe0ae23a888f944 598 Gene3D G3DSA:3.40.50.970 369 520 1.3E-17 T 23-10-2018 STK_07320 414359c09fd2317d0fe0ae23a888f944 598 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 15 179 2.2E-13 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 STK_07320 414359c09fd2317d0fe0ae23a888f944 598 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 376 511 6.2E-23 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 STK_07320 414359c09fd2317d0fe0ae23a888f944 598 SUPERFAMILY SSF54862 526 594 3.49E-15 T 23-10-2018 STK_07320 414359c09fd2317d0fe0ae23a888f944 598 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 567 578 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_07320 414359c09fd2317d0fe0ae23a888f944 598 PIRSF PIRSF006439 1 588 1.3E-195 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 STK_24110 5a5f8cd33da5a2ffec45b2b435c40141 584 PRINTS PR00762 Chloride channel signature 172 191 3.4E-20 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 STK_24110 5a5f8cd33da5a2ffec45b2b435c40141 584 PRINTS PR00762 Chloride channel signature 397 416 3.4E-20 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 STK_24110 5a5f8cd33da5a2ffec45b2b435c40141 584 PRINTS PR00762 Chloride channel signature 344 364 3.4E-20 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 STK_24110 5a5f8cd33da5a2ffec45b2b435c40141 584 PRINTS PR00762 Chloride channel signature 379 395 3.4E-20 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 STK_24110 5a5f8cd33da5a2ffec45b2b435c40141 584 PRINTS PR00762 Chloride channel signature 121 140 3.4E-20 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 STK_24110 5a5f8cd33da5a2ffec45b2b435c40141 584 SUPERFAMILY SSF81340 4 447 7.46E-102 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 STK_24110 5a5f8cd33da5a2ffec45b2b435c40141 584 Pfam PF00654 Voltage gated chloride channel 78 429 2.2E-89 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 STK_24110 5a5f8cd33da5a2ffec45b2b435c40141 584 Gene3D G3DSA:1.10.3080.10 10 453 2.3E-95 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 STK_24110 5a5f8cd33da5a2ffec45b2b435c40141 584 SMART SM00116 467 515 1.2 T 23-10-2018 IPR000644 CBS domain STK_24110 5a5f8cd33da5a2ffec45b2b435c40141 584 SMART SM00116 526 573 0.044 T 23-10-2018 IPR000644 CBS domain STK_24110 5a5f8cd33da5a2ffec45b2b435c40141 584 Pfam PF00571 CBS domain 520 571 4.0E-6 T 23-10-2018 IPR000644 CBS domain STK_24110 5a5f8cd33da5a2ffec45b2b435c40141 584 Pfam PF00571 CBS domain 474 511 0.0076 T 23-10-2018 IPR000644 CBS domain STK_24110 5a5f8cd33da5a2ffec45b2b435c40141 584 SUPERFAMILY SSF54631 456 577 8.72E-22 T 23-10-2018 STK_24110 5a5f8cd33da5a2ffec45b2b435c40141 584 Gene3D G3DSA:3.10.580.10 466 575 7.7E-16 T 23-10-2018 STK_07415 8b118de8f6052b2ec3bb66d3e4b5e1ee 79 Gene3D G3DSA:2.10.260.10 2 43 7.7E-17 T 23-10-2018 STK_07415 8b118de8f6052b2ec3bb66d3e4b5e1ee 79 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 2 46 4.1E-19 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_07415 8b118de8f6052b2ec3bb66d3e4b5e1ee 79 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 3 47 6.3E-13 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_07415 8b118de8f6052b2ec3bb66d3e4b5e1ee 79 SMART SM00966 3 50 7.4E-13 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_07415 8b118de8f6052b2ec3bb66d3e4b5e1ee 79 SUPERFAMILY SSF89447 3 62 1.08E-11 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily STK_13080 263e7926cfe9a16404f32f7488fbea38 428 Pfam PF02195 ParB-like nuclease domain 11 87 2.5E-11 T 23-10-2018 IPR003115 ParB/Sulfiredoxin STK_13080 263e7926cfe9a16404f32f7488fbea38 428 Gene3D G3DSA:3.90.1530.30 26 79 2.7E-7 T 23-10-2018 STK_13080 263e7926cfe9a16404f32f7488fbea38 428 SUPERFAMILY SSF110849 9 96 1.19E-13 T 23-10-2018 IPR036086 ParB/Sulfiredoxin superfamily STK_13080 263e7926cfe9a16404f32f7488fbea38 428 SMART SM00470 8 95 1.9E-19 T 23-10-2018 IPR003115 ParB/Sulfiredoxin STK_19520 4d1fb3fab15aee727963765ba7f4160e 353 Pfam PF04693 Archaeal putative transposase ISC1217 1 325 6.5E-174 T 23-10-2018 IPR006783 Transposase, ISC1217 STK_20170 e8e1e25f2c01f467d4e01de77a02526a 599 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 70 - T 23-10-2018 IPR010916 TonB box, conserved site STK_20170 e8e1e25f2c01f467d4e01de77a02526a 599 SUPERFAMILY SSF48208 217 597 1.4E-100 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 STK_20170 e8e1e25f2c01f467d4e01de77a02526a 599 Pfam PF00723 Glycosyl hydrolases family 15 344 544 1.0E-14 T 23-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 STK_20170 e8e1e25f2c01f467d4e01de77a02526a 599 SUPERFAMILY SSF74650 83 237 4.39E-5 T 23-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 STK_20170 e8e1e25f2c01f467d4e01de77a02526a 599 Gene3D G3DSA:1.50.10.10 243 597 1.6E-81 T 23-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 STK_18480 b3b96133aa488de4cd2cc872f98a37ad 230 Gene3D G3DSA:3.60.20.10 1 182 4.4E-13 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_18480 b3b96133aa488de4cd2cc872f98a37ad 230 Pfam PF13230 Glutamine amidotransferases class-II 31 135 1.6E-6 T 23-10-2018 IPR026869 Putative glutamine amidotransferase type 2 STK_18480 b3b96133aa488de4cd2cc872f98a37ad 230 SUPERFAMILY SSF56235 2 181 9.11E-15 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_20240 d69d7f4d24c333382c836a2d8120b4f6 151 Pfam PF00293 NUDIX domain 6 110 1.4E-13 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 STK_20240 d69d7f4d24c333382c836a2d8120b4f6 151 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 96 114 2.9E-6 T 23-10-2018 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502|Reactome: R-HSA-2393930 STK_20240 d69d7f4d24c333382c836a2d8120b4f6 151 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 115 133 2.9E-6 T 23-10-2018 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502|Reactome: R-HSA-2393930 STK_20240 d69d7f4d24c333382c836a2d8120b4f6 151 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 18 34 2.9E-6 T 23-10-2018 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502|Reactome: R-HSA-2393930 STK_20240 d69d7f4d24c333382c836a2d8120b4f6 151 ProSitePatterns PS00893 Nudix box signature. 34 55 - T 23-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 STK_20240 d69d7f4d24c333382c836a2d8120b4f6 151 SUPERFAMILY SSF55811 3 127 3.38E-21 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 STK_20240 d69d7f4d24c333382c836a2d8120b4f6 151 Gene3D G3DSA:3.90.79.10 1 141 1.2E-35 T 23-10-2018 STK_15720 33c1b0cea8faedfce662bda6f41bc542 135 SUPERFAMILY SSF88723 1 128 4.77E-14 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_15720 33c1b0cea8faedfce662bda6f41bc542 135 Gene3D G3DSA:3.40.50.1010 2 135 2.1E-5 T 23-10-2018 STK_15720 33c1b0cea8faedfce662bda6f41bc542 135 Pfam PF01850 PIN domain 3 124 1.5E-10 T 23-10-2018 IPR002716 PIN domain STK_17150 a773f372f4d199384ec71fe56914ae28 740 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 659 671 3.9E-19 T 23-10-2018 STK_17150 a773f372f4d199384ec71fe56914ae28 740 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 588 598 3.9E-19 T 23-10-2018 STK_17150 a773f372f4d199384ec71fe56914ae28 740 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 636 655 3.9E-19 T 23-10-2018 STK_17150 a773f372f4d199384ec71fe56914ae28 740 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 466 480 3.9E-19 T 23-10-2018 STK_17150 a773f372f4d199384ec71fe56914ae28 740 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 316 330 3.9E-19 T 23-10-2018 STK_17150 a773f372f4d199384ec71fe56914ae28 740 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 245 726 6.5E-74 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 STK_17150 a773f372f4d199384ec71fe56914ae28 740 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 241 735 2.8E-107 T 23-10-2018 STK_17150 a773f372f4d199384ec71fe56914ae28 740 SUPERFAMILY SSF56784 464 736 1.01E-35 T 23-10-2018 IPR036412 HAD-like superfamily STK_17150 a773f372f4d199384ec71fe56914ae28 740 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 193 736 8.1E-143 T 23-10-2018 STK_17150 a773f372f4d199384ec71fe56914ae28 740 SUPERFAMILY SSF55008 17 79 1.44E-16 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 STK_17150 a773f372f4d199384ec71fe56914ae28 740 ProSitePatterns PS01047 Heavy-metal-associated domain. 21 50 - T 23-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 STK_17150 a773f372f4d199384ec71fe56914ae28 740 Gene3D G3DSA:3.40.50.1000 446 670 7.5E-56 T 23-10-2018 IPR023214 HAD superfamily STK_17150 a773f372f4d199384ec71fe56914ae28 740 SUPERFAMILY SSF81665 367 706 5.36E-11 T 23-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 STK_17150 a773f372f4d199384ec71fe56914ae28 740 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 468 474 - T 23-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 STK_17150 a773f372f4d199384ec71fe56914ae28 740 Gene3D G3DSA:2.70.150.20 252 370 4.4E-28 T 23-10-2018 STK_17150 a773f372f4d199384ec71fe56914ae28 740 SUPERFAMILY SSF81653 281 365 1.57E-22 T 23-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 STK_17150 a773f372f4d199384ec71fe56914ae28 740 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 211 737 3.4E-140 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 STK_17150 a773f372f4d199384ec71fe56914ae28 740 Pfam PF00702 haloacid dehalogenase-like hydrolase 463 649 2.3E-32 T 23-10-2018 STK_17150 a773f372f4d199384ec71fe56914ae28 740 SUPERFAMILY SSF55008 81 147 5.63E-7 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 STK_17150 a773f372f4d199384ec71fe56914ae28 740 Pfam PF00122 E1-E2 ATPase 282 446 3.0E-50 T 23-10-2018 STK_17150 a773f372f4d199384ec71fe56914ae28 740 Gene3D G3DSA:3.30.70.100 91 155 4.1E-5 T 23-10-2018 STK_17150 a773f372f4d199384ec71fe56914ae28 740 Gene3D G3DSA:3.40.1110.10 476 574 7.5E-56 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 STK_17150 a773f372f4d199384ec71fe56914ae28 740 Pfam PF00403 Heavy-metal-associated domain 19 77 3.1E-14 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 STK_17150 a773f372f4d199384ec71fe56914ae28 740 Gene3D G3DSA:3.30.70.100 15 79 9.8E-18 T 23-10-2018 STK_09405 5f0758ca0f418b14b258ee93f8938645 56 Hamap MF_00803 Ribosome biogenesis protein Nop10 [nop10]. 3 53 17.814 T 23-10-2018 IPR023532 H/ACA ribonucleoprotein complex subunit Nop10 , archaeal-type GO:0001522|GO:0030515|GO:0042254 STK_09405 5f0758ca0f418b14b258ee93f8938645 56 Pfam PF04135 Nucleolar RNA-binding protein, Nop10p family 1 50 4.8E-26 T 23-10-2018 IPR007264 H/ACA ribonucleoprotein complex, subunit Nop10 GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 STK_09405 5f0758ca0f418b14b258ee93f8938645 56 Gene3D G3DSA:2.20.28.40 1 55 2.8E-24 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 STK_09405 5f0758ca0f418b14b258ee93f8938645 56 SUPERFAMILY SSF144210 3 53 2.09E-21 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 STK_14360 7e31af1d9bc4f620a3fd29a4a1fd29e6 592 Gene3D G3DSA:2.40.50.100 117 187 2.0E-173 T 23-10-2018 STK_14360 7e31af1d9bc4f620a3fd29a4a1fd29e6 592 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 214 437 3.9E-85 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 STK_14360 7e31af1d9bc4f620a3fd29a4a1fd29e6 592 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 85 205 9.1E-48 T 23-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 STK_14360 7e31af1d9bc4f620a3fd29a4a1fd29e6 592 Gene3D G3DSA:3.40.50.300 73 437 2.0E-173 T 23-10-2018 STK_14360 7e31af1d9bc4f620a3fd29a4a1fd29e6 592 SUPERFAMILY SSF52540 167 443 2.62E-77 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_14360 7e31af1d9bc4f620a3fd29a4a1fd29e6 592 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 2 591 51.653 T 23-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 STK_14360 7e31af1d9bc4f620a3fd29a4a1fd29e6 592 SUPERFAMILY SSF50615 3 72 5.89E-14 T 23-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 STK_14360 7e31af1d9bc4f620a3fd29a4a1fd29e6 592 Gene3D G3DSA:1.10.1140.10 438 592 1.3E-49 T 23-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 STK_14360 7e31af1d9bc4f620a3fd29a4a1fd29e6 592 SUPERFAMILY SSF47917 450 536 6.28E-21 T 23-10-2018 STK_14360 7e31af1d9bc4f620a3fd29a4a1fd29e6 592 TIGRFAM TIGR01043 ATP_syn_A_arch: ATP synthase archaeal, A subunit 4 584 0.0 T 23-10-2018 IPR005726 ATP synthase alpha chain, archaea GO:0015986|GO:0033178|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 STK_14360 7e31af1d9bc4f620a3fd29a4a1fd29e6 592 SMART SM00382 226 414 1.4E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_14360 7e31af1d9bc4f620a3fd29a4a1fd29e6 592 Gene3D G3DSA:2.40.30.20 1 72 1.3E-26 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 STK_14360 7e31af1d9bc4f620a3fd29a4a1fd29e6 592 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 7 69 1.5E-13 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 STK_25840 82fc01be257049629d76c40cf4518058 700 Gene3D G3DSA:3.40.50.300 426 688 5.4E-97 T 23-10-2018 STK_25840 82fc01be257049629d76c40cf4518058 700 SUPERFAMILY SSF52540 165 416 5.66E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_25840 82fc01be257049629d76c40cf4518058 700 SMART SM01073 13 87 2.3E-6 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain STK_25840 82fc01be257049629d76c40cf4518058 700 Gene3D G3DSA:1.10.8.60 600 674 5.4E-97 T 23-10-2018 STK_25840 82fc01be257049629d76c40cf4518058 700 Gene3D G3DSA:3.40.50.300 156 337 1.3E-67 T 23-10-2018 STK_25840 82fc01be257049629d76c40cf4518058 700 SMART SM00382 203 339 2.6E-25 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_25840 82fc01be257049629d76c40cf4518058 700 SMART SM00382 464 601 4.1E-22 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_25840 82fc01be257049629d76c40cf4518058 700 SUPERFAMILY SSF52540 426 690 4.6E-68 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_25840 82fc01be257049629d76c40cf4518058 700 ProSitePatterns PS00674 AAA-protein family signature. 569 587 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 STK_25840 82fc01be257049629d76c40cf4518058 700 Pfam PF09336 Vps4 C terminal oligomerisation domain 658 691 1.5E-4 T 23-10-2018 IPR015415 Vps4 oligomerisation, C-terminal STK_25840 82fc01be257049629d76c40cf4518058 700 Gene3D G3DSA:1.10.8.60 338 422 1.4E-26 T 23-10-2018 STK_25840 82fc01be257049629d76c40cf4518058 700 ProSitePatterns PS00674 AAA-protein family signature. 307 325 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 STK_25840 82fc01be257049629d76c40cf4518058 700 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 468 598 9.5E-48 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_25840 82fc01be257049629d76c40cf4518058 700 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 207 336 2.7E-48 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_25840 82fc01be257049629d76c40cf4518058 700 SUPERFAMILY SSF50692 11 85 1.37E-5 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily STK_09670 cbd555d216d029626908d83933f4c167 156 Gene3D G3DSA:3.30.160.70 1 67 4.1E-46 T 23-10-2018 STK_09670 cbd555d216d029626908d83933f4c167 156 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 71 146 4.8E-26 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 STK_09670 cbd555d216d029626908d83933f4c167 156 SUPERFAMILY SSF46767 70 148 2.88E-24 T 23-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 STK_09670 cbd555d216d029626908d83933f4c167 156 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 71 148 1.1E-23 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 STK_09670 cbd555d216d029626908d83933f4c167 156 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 118 124 - T 23-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 STK_09670 cbd555d216d029626908d83933f4c167 156 Gene3D G3DSA:1.10.10.10 68 156 2.1E-33 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_09670 cbd555d216d029626908d83933f4c167 156 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 5 147 34.926 T 23-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 STK_09670 cbd555d216d029626908d83933f4c167 156 SUPERFAMILY SSF53155 4 66 1.02E-5 T 23-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 STK_06590 93061b776436a3c8e81d0a8f3e47fdc0 192 Gene3D G3DSA:3.40.50.720 36 171 2.9E-21 T 23-10-2018 STK_06590 93061b776436a3c8e81d0a8f3e47fdc0 192 Pfam PF13478 XdhC Rossmann domain 39 166 3.8E-23 T 23-10-2018 IPR027051 XdhC Rossmann domain STK_01870 ddf0c8a334d1a893a540e1b58d6f807a 306 Gene3D G3DSA:3.90.25.10 167 289 8.5E-84 T 23-10-2018 STK_01870 ddf0c8a334d1a893a540e1b58d6f807a 306 SUPERFAMILY SSF51735 1 302 2.27E-71 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_01870 ddf0c8a334d1a893a540e1b58d6f807a 306 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 228 5.8E-45 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 STK_01870 ddf0c8a334d1a893a540e1b58d6f807a 306 Gene3D G3DSA:3.40.50.720 4 228 8.5E-84 T 23-10-2018 STK_17590 17f551643fc2f53a55c505876857e751 137 Pfam PF05168 HEPN domain 8 126 1.1E-23 T 23-10-2018 IPR007842 HEPN domain STK_17590 17f551643fc2f53a55c505876857e751 137 SUPERFAMILY SSF81593 10 122 5.1E-16 T 23-10-2018 STK_17590 17f551643fc2f53a55c505876857e751 137 Gene3D G3DSA:1.20.120.330 2 129 2.5E-15 T 23-10-2018 STK_17590 17f551643fc2f53a55c505876857e751 137 SMART SM00748 11 121 1.2E-31 T 23-10-2018 IPR007842 HEPN domain STK_14140 8ae878f0722e82a3aae6c0950e03f9a2 255 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 4.7E-6 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 STK_14140 8ae878f0722e82a3aae6c0950e03f9a2 255 PRINTS PR00111 Alpha/beta hydrolase fold signature 203 217 4.7E-6 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 STK_14140 8ae878f0722e82a3aae6c0950e03f9a2 255 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 4.7E-6 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 STK_14140 8ae878f0722e82a3aae6c0950e03f9a2 255 SUPERFAMILY SSF53474 5 255 1.34E-50 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold STK_14140 8ae878f0722e82a3aae6c0950e03f9a2 255 Pfam PF00561 alpha/beta hydrolase fold 23 132 1.4E-19 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 STK_14140 8ae878f0722e82a3aae6c0950e03f9a2 255 Gene3D G3DSA:3.40.50.1820 3 255 9.2E-52 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold STK_15680 86486fc05352b992ef028ab49ed2e478 459 Pfam PF14403 Circularly permuted ATP-grasp type 2 87 436 3.7E-84 T 23-10-2018 IPR025841 Circularly permuted ATP-grasp type 2 STK_15680 86486fc05352b992ef028ab49ed2e478 459 PIRSF PIRSF005522 1 459 1.5E-140 T 23-10-2018 IPR016450 Uncharacterised conserved protein UCP005522 STK_15680 86486fc05352b992ef028ab49ed2e478 459 SUPERFAMILY SSF56059 63 451 8.24E-37 T 23-10-2018 STK_15680 86486fc05352b992ef028ab49ed2e478 459 Gene3D G3DSA:3.40.50.11290 216 310 2.0E-22 T 23-10-2018 STK_04630 3061043c46a8b4c5cc3643e586c03fcc 358 Gene3D G3DSA:3.40.50.300 68 250 6.4E-20 T 23-10-2018 STK_04630 3061043c46a8b4c5cc3643e586c03fcc 358 SUPERFAMILY SSF52540 77 244 4.68E-5 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_04630 3061043c46a8b4c5cc3643e586c03fcc 358 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 83 245 6.5E-28 T 23-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain STK_12895 2b128b08ed4244481e63db9333455bb3 99 Pfam PF01918 Alba 11 74 2.8E-22 T 23-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 STK_12895 2b128b08ed4244481e63db9333455bb3 99 Gene3D G3DSA:3.30.110.20 2 98 2.8E-34 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 STK_12895 2b128b08ed4244481e63db9333455bb3 99 SUPERFAMILY SSF82704 11 97 3.79E-28 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 STK_12895 2b128b08ed4244481e63db9333455bb3 99 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 1 97 28.257 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 STK_12895 2b128b08ed4244481e63db9333455bb3 99 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 11 97 2.3E-37 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 STK_12895 2b128b08ed4244481e63db9333455bb3 99 PIRSF PIRSF028732 7 98 1.1E-36 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 STK_12895 2b128b08ed4244481e63db9333455bb3 99 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 14 98 1.0E-41 T 23-10-2018 STK_01360 ea0fc29316d864556d903e327b565d58 518 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 28 465 1.3E-70 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01360 ea0fc29316d864556d903e327b565d58 518 PRINTS PR01165 Cytochrome c oxidase subunit I signature 373 392 1.5E-17 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01360 ea0fc29316d864556d903e327b565d58 518 PRINTS PR01165 Cytochrome c oxidase subunit I signature 192 211 1.5E-17 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01360 ea0fc29316d864556d903e327b565d58 518 PRINTS PR01165 Cytochrome c oxidase subunit I signature 308 329 1.5E-17 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01360 ea0fc29316d864556d903e327b565d58 518 PRINTS PR01165 Cytochrome c oxidase subunit I signature 238 259 1.5E-17 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01360 ea0fc29316d864556d903e327b565d58 518 PRINTS PR01165 Cytochrome c oxidase subunit I signature 284 299 1.5E-17 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01360 ea0fc29316d864556d903e327b565d58 518 PRINTS PR01165 Cytochrome c oxidase subunit I signature 64 87 1.5E-17 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01360 ea0fc29316d864556d903e327b565d58 518 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 240 294 - T 23-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01360 ea0fc29316d864556d903e327b565d58 518 Gene3D G3DSA:1.20.210.10 12 508 3.4E-70 T 23-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01360 ea0fc29316d864556d903e327b565d58 518 SUPERFAMILY SSF81442 24 479 8.63E-80 T 23-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_05363 5d838e15d345e7d75591a34effbb3a2e 75 SUPERFAMILY SSF54909 2 75 6.44E-14 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel STK_05363 5d838e15d345e7d75591a34effbb3a2e 75 Pfam PF01037 Lrp/AsnC ligand binding domain 10 75 1.4E-11 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain STK_05363 5d838e15d345e7d75591a34effbb3a2e 75 Gene3D G3DSA:3.30.70.920 3 74 8.3E-21 T 23-10-2018 STK_18730 c03f346ba8cbc58861859d43af6c910d 365 SUPERFAMILY SSF51905 5 349 1.29E-25 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_18730 c03f346ba8cbc58861859d43af6c910d 365 SUPERFAMILY SSF51905 157 345 5.59E-8 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_18730 c03f346ba8cbc58861859d43af6c910d 365 Gene3D G3DSA:3.50.50.60 4 151 2.0E-16 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_18730 c03f346ba8cbc58861859d43af6c910d 365 Gene3D G3DSA:3.50.50.60 204 348 3.3E-5 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_18730 c03f346ba8cbc58861859d43af6c910d 365 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 335 1.2E-17 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 STK_18730 c03f346ba8cbc58861859d43af6c910d 365 PRINTS PR00419 Adrenodoxin reductase family signature 5 27 9.8E-6 T 23-10-2018 STK_18730 c03f346ba8cbc58861859d43af6c910d 365 PRINTS PR00419 Adrenodoxin reductase family signature 28 41 9.8E-6 T 23-10-2018 STK_20130 94b626cc668d07c34f07f54e6e48a004 388 SUPERFAMILY SSF52540 13 162 5.6E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_07070 caf69e8d89eb04d6bef11370d360ef0d 560 SUPERFAMILY SSF103473 5 213 1.7E-27 T 23-10-2018 IPR036259 MFS transporter superfamily STK_07070 caf69e8d89eb04d6bef11370d360ef0d 560 Gene3D G3DSA:1.20.1720.10 12 233 1.3E-27 T 23-10-2018 STK_07070 caf69e8d89eb04d6bef11370d360ef0d 560 Gene3D G3DSA:1.20.1250.20 264 466 8.9E-17 T 23-10-2018 STK_07070 caf69e8d89eb04d6bef11370d360ef0d 560 Pfam PF07690 Major Facilitator Superfamily 219 425 2.1E-14 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_07070 caf69e8d89eb04d6bef11370d360ef0d 560 Pfam PF07690 Major Facilitator Superfamily 13 187 4.8E-25 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_07070 caf69e8d89eb04d6bef11370d360ef0d 560 SUPERFAMILY SSF103473 221 458 1.28E-22 T 23-10-2018 IPR036259 MFS transporter superfamily STK_07650 0bf6475ce29192d4016f497d39858407 328 Pfam PF09376 NurA domain 55 300 1.4E-24 T 23-10-2018 IPR018977 NurA domain STK_07650 0bf6475ce29192d4016f497d39858407 328 SMART SM00933 52 300 2.0E-38 T 23-10-2018 IPR018977 NurA domain STK_06490 def84d63889be9e291bd4b08327d69a6 440 Gene3D G3DSA:1.10.45.10 386 430 4.7E-6 T 23-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 STK_06490 def84d63889be9e291bd4b08327d69a6 440 Gene3D G3DSA:3.30.465.40 6 220 1.7E-68 T 23-10-2018 STK_06490 def84d63889be9e291bd4b08327d69a6 440 SUPERFAMILY SSF55103 204 430 9.48E-44 T 23-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 STK_06490 def84d63889be9e291bd4b08327d69a6 440 Gene3D G3DSA:3.30.70.2740 310 385 6.3E-14 T 23-10-2018 STK_06490 def84d63889be9e291bd4b08327d69a6 440 Pfam PF01565 FAD binding domain 23 161 1.0E-45 T 23-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 STK_06490 def84d63889be9e291bd4b08327d69a6 440 SUPERFAMILY SSF56176 20 199 9.35E-61 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 STK_06490 def84d63889be9e291bd4b08327d69a6 440 Pfam PF02913 FAD linked oxidases, C-terminal domain 203 428 2.2E-43 T 23-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 STK_11050 c47dbd58396e3290dbbe3030c264b0da 297 SUPERFAMILY SSF161098 15 287 2.75E-43 T 23-10-2018 IPR035906 MetI-like superfamily STK_11050 c47dbd58396e3290dbbe3030c264b0da 297 Gene3D G3DSA:1.10.3720.10 8 283 1.5E-45 T 23-10-2018 IPR035906 MetI-like superfamily STK_11050 c47dbd58396e3290dbbe3030c264b0da 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 287 4.1E-13 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 STK_22550 1efcede8e52e1253b9e53b35b3eccd7c 409 PRINTS PR00758 Arsenical pump membrane protein signature 268 292 4.1E-6 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 STK_22550 1efcede8e52e1253b9e53b35b3eccd7c 409 PRINTS PR00758 Arsenical pump membrane protein signature 175 198 4.1E-6 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 STK_22550 1efcede8e52e1253b9e53b35b3eccd7c 409 PRINTS PR00758 Arsenical pump membrane protein signature 100 124 4.1E-6 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 STK_22550 1efcede8e52e1253b9e53b35b3eccd7c 409 Pfam PF03600 Citrate transporter 24 347 3.5E-35 T 23-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 STK_22870 b4d15f055a5fe11725a92850c0a1350c 235 Gene3D G3DSA:3.40.50.720 1 234 2.5E-45 T 23-10-2018 STK_22870 b4d15f055a5fe11725a92850c0a1350c 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 2.6E-12 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_22870 b4d15f055a5fe11725a92850c0a1350c 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 2.6E-12 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_22870 b4d15f055a5fe11725a92850c0a1350c 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 2.6E-12 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_22870 b4d15f055a5fe11725a92850c0a1350c 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.6E-12 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_22870 b4d15f055a5fe11725a92850c0a1350c 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 215 2.6E-12 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_22870 b4d15f055a5fe11725a92850c0a1350c 235 SUPERFAMILY SSF51735 1 232 2.61E-45 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_22870 b4d15f055a5fe11725a92850c0a1350c 235 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 231 1.7E-26 T 23-10-2018 STK_04610 f8ff53c6d77735eb04fda4f77f0b7305 119 Pfam PF06677 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 9 47 1.2E-13 T 23-10-2018 IPR009563 Sjoegren syndrome/scleroderma autoantigen 1 STK_24660 d4b43cb26c375e04e4af67d918b06105 114 Pfam PF02656 Domain of unknown function (DUF202) 5 76 4.7E-21 T 23-10-2018 IPR003807 Domain of unknown function DUF202 STK_06880 28451247ae8f055760e7b26c42f2a9e0 262 Pfam PF13649 Methyltransferase domain 50 153 1.1E-8 T 23-10-2018 STK_06880 28451247ae8f055760e7b26c42f2a9e0 262 SUPERFAMILY SSF53335 24 196 2.48E-15 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_06880 28451247ae8f055760e7b26c42f2a9e0 262 Gene3D G3DSA:3.40.50.150 27 183 6.1E-15 T 23-10-2018 STK_02775 e688537f6fe78659396eaf4ba1509734 84 SUPERFAMILY SSF55287 8 82 7.98E-28 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 STK_02775 e688537f6fe78659396eaf4ba1509734 84 Pfam PF01191 RNA polymerase Rpb5, C-terminal domain 11 81 1.1E-30 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 STK_02775 e688537f6fe78659396eaf4ba1509734 84 ProDom PD005155 RNA POLYMERASE DNA-DIRECTED SUBUNIT NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION II H POLYPEPTIDE 15 82 2.0E-31 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 STK_02775 e688537f6fe78659396eaf4ba1509734 84 Gene3D G3DSA:3.90.940.20 1 84 7.4E-35 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 STK_02775 e688537f6fe78659396eaf4ba1509734 84 Hamap MF_00025 DNA-directed RNA polymerase subunit H [rpoH]. 9 82 23.208 T 23-10-2018 IPR020609 Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 STK_02775 e688537f6fe78659396eaf4ba1509734 84 ProSitePatterns PS01110 RNA polymerases H / 23 Kd subunits signature. 14 27 - T 23-10-2018 IPR020608 RNA polymerase, subunit H/Rpb5, conserved site Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 STK_22800 b3e9e80877665e068f340d4ec50433e4 548 Gene3D G3DSA:3.40.50.300 4 335 7.0E-108 T 23-10-2018 STK_22800 b3e9e80877665e068f340d4ec50433e4 548 SMART SM00488 3 221 0.0026 T 23-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 STK_22800 b3e9e80877665e068f340d4ec50433e4 548 Pfam PF13307 Helicase C-terminal domain 382 533 2.5E-25 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 STK_22800 b3e9e80877665e068f340d4ec50433e4 548 Gene3D G3DSA:3.40.50.300 351 548 1.7E-56 T 23-10-2018 STK_22800 b3e9e80877665e068f340d4ec50433e4 548 SUPERFAMILY SSF52540 2 323 4.47E-13 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_22800 b3e9e80877665e068f340d4ec50433e4 548 SUPERFAMILY SSF52540 24 536 7.34E-5 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_22800 b3e9e80877665e068f340d4ec50433e4 548 Pfam PF06733 DEAD_2 90 185 5.9E-16 T 23-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 STK_22800 b3e9e80877665e068f340d4ec50433e4 548 SMART SM00491 399 531 1.2E-15 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 STK_22800 b3e9e80877665e068f340d4ec50433e4 548 Gene3D G3DSA:1.10.275.30 189 296 7.0E-108 T 23-10-2018 STK_16500 2cd57052097a1077d9b8e37689f43e2b 490 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 398 419 9.8E-66 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 STK_16500 2cd57052097a1077d9b8e37689f43e2b 490 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 225 241 9.8E-66 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 STK_16500 2cd57052097a1077d9b8e37689f43e2b 490 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 375 392 9.8E-66 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 STK_16500 2cd57052097a1077d9b8e37689f43e2b 490 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 289 305 9.8E-66 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 STK_16500 2cd57052097a1077d9b8e37689f43e2b 490 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 329 348 9.8E-66 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 STK_16500 2cd57052097a1077d9b8e37689f43e2b 490 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 144 164 9.8E-66 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 STK_16500 2cd57052097a1077d9b8e37689f43e2b 490 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 262 281 9.8E-66 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 STK_16500 2cd57052097a1077d9b8e37689f43e2b 490 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 242 261 9.8E-66 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 STK_16500 2cd57052097a1077d9b8e37689f43e2b 490 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 7 487 3.6E-95 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 STK_16500 2cd57052097a1077d9b8e37689f43e2b 490 PIRSF PIRSF006615 1 490 2.8E-198 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 STK_16500 2cd57052097a1077d9b8e37689f43e2b 490 Gene3D G3DSA:1.10.1370.30 1 488 5.3E-180 T 23-10-2018 STK_16500 2cd57052097a1077d9b8e37689f43e2b 490 SUPERFAMILY SSF55486 3 488 2.29E-107 T 23-10-2018 STK_13087 a68eeafc552fd0803f0eb6ff44207dd3 143 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 20 125 1.5E-13 T 23-10-2018 IPR006440 Death on curing protein GO:0016301 STK_13087 a68eeafc552fd0803f0eb6ff44207dd3 143 SUPERFAMILY SSF140931 58 97 2.75E-7 T 23-10-2018 IPR036597 Fido-like domain superfamily STK_13087 a68eeafc552fd0803f0eb6ff44207dd3 143 Pfam PF02661 Fic/DOC family 57 90 5.3E-7 T 23-10-2018 IPR003812 Fido domain STK_13087 a68eeafc552fd0803f0eb6ff44207dd3 143 Gene3D G3DSA:1.20.120.1870 10 142 1.9E-10 T 23-10-2018 STK_22440 04de4facd7a7b6014957bd9634ae71df 468 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 466 1.6E-152 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 STK_22440 04de4facd7a7b6014957bd9634ae71df 468 SUPERFAMILY SSF47323 339 467 6.15E-24 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_22440 04de4facd7a7b6014957bd9634ae71df 468 SUPERFAMILY SSF52374 3 312 6.7E-96 T 23-10-2018 STK_22440 04de4facd7a7b6014957bd9634ae71df 468 Gene3D G3DSA:3.40.50.620 1 303 8.0E-134 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_22440 04de4facd7a7b6014957bd9634ae71df 468 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 468 34.747 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 STK_22440 04de4facd7a7b6014957bd9634ae71df 468 Pfam PF09190 DALR domain 354 411 3.1E-5 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 STK_22440 04de4facd7a7b6014957bd9634ae71df 468 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 312 1.2E-125 T 23-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 STK_22440 04de4facd7a7b6014957bd9634ae71df 468 SMART SM00840 353 412 1.8E-5 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 STK_22440 04de4facd7a7b6014957bd9634ae71df 468 Gene3D G3DSA:1.20.120.640 304 467 1.5E-21 T 23-10-2018 STK_22440 04de4facd7a7b6014957bd9634ae71df 468 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 189 207 6.2E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 STK_22440 04de4facd7a7b6014957bd9634ae71df 468 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 220 241 6.2E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 STK_22440 04de4facd7a7b6014957bd9634ae71df 468 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 6.2E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 STK_22440 04de4facd7a7b6014957bd9634ae71df 468 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 6.2E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 STK_03480 4dc30cc988a0aeed9414f544df619546 654 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 7 650 6.4E-239 T 23-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 STK_03480 4dc30cc988a0aeed9414f544df619546 654 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 1 51 2.2E-15 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_03480 4dc30cc988a0aeed9414f544df619546 654 Gene3D G3DSA:3.40.228.10 135 331 4.2E-142 T 23-10-2018 STK_03480 4dc30cc988a0aeed9414f544df619546 654 SUPERFAMILY SSF50692 539 653 3.62E-22 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily STK_03480 4dc30cc988a0aeed9414f544df619546 654 Pfam PF00384 Molybdopterin oxidoreductase 58 471 4.2E-75 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_03480 4dc30cc988a0aeed9414f544df619546 654 SMART SM00926 1 55 8.4E-16 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_03480 4dc30cc988a0aeed9414f544df619546 654 Gene3D G3DSA:3.40.50.740 67 502 4.2E-142 T 23-10-2018 STK_03480 4dc30cc988a0aeed9414f544df619546 654 Pfam PF01568 Molydopterin dinucleotide binding domain 546 646 1.2E-23 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 STK_03480 4dc30cc988a0aeed9414f544df619546 654 Gene3D G3DSA:2.20.25.90 1 53 9.2E-15 T 23-10-2018 STK_03480 4dc30cc988a0aeed9414f544df619546 654 Gene3D G3DSA:2.40.40.20 544 653 2.6E-20 T 23-10-2018 STK_03480 4dc30cc988a0aeed9414f544df619546 654 SUPERFAMILY SSF53706 2 508 9.03E-173 T 23-10-2018 STK_05990 c78596f64399e7fe70319159187e8790 415 ProSitePatterns PS01244 Aconitase family signature 2. 347 360 - T 23-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 STK_05990 c78596f64399e7fe70319159187e8790 415 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 3 413 3.6E-190 T 23-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 STK_05990 c78596f64399e7fe70319159187e8790 415 PRINTS PR00415 Aconitase family signature 111 124 2.1E-12 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 STK_05990 c78596f64399e7fe70319159187e8790 415 PRINTS PR00415 Aconitase family signature 293 304 2.1E-12 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 STK_05990 c78596f64399e7fe70319159187e8790 415 PRINTS PR00415 Aconitase family signature 347 360 2.1E-12 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 STK_05990 c78596f64399e7fe70319159187e8790 415 PRINTS PR00415 Aconitase family signature 125 140 2.1E-12 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 STK_05990 c78596f64399e7fe70319159187e8790 415 SUPERFAMILY SSF53732 2 414 3.66E-126 T 23-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 STK_05990 c78596f64399e7fe70319159187e8790 415 Gene3D G3DSA:3.30.499.20 4 267 3.0E-82 T 23-10-2018 STK_05990 c78596f64399e7fe70319159187e8790 415 Pfam PF00330 Aconitase family (aconitate hydratase) 25 406 2.2E-76 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 STK_05990 c78596f64399e7fe70319159187e8790 415 Gene3D G3DSA:3.30.499.10 270 415 1.3E-52 T 23-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 STK_05990 c78596f64399e7fe70319159187e8790 415 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 4 412 1.7E-146 T 23-10-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 STK_05990 c78596f64399e7fe70319159187e8790 415 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 3 414 46.916 T 23-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 STK_22680 15046b47ccb2ed2cb8f2e30a9e64e814 273 Gene3D G3DSA:3.40.50.970 11 272 1.7E-77 T 23-10-2018 STK_22680 15046b47ccb2ed2cb8f2e30a9e64e814 273 SUPERFAMILY SSF52518 11 263 8.2E-72 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold STK_22680 15046b47ccb2ed2cb8f2e30a9e64e814 273 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 37 263 6.9E-31 T 23-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 STK_08060 d4145c85879871a2da046fd5966390eb 157 PIRSF PIRSF001338 1 157 1.5E-71 T 23-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 STK_08060 d4145c85879871a2da046fd5966390eb 157 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 4 155 33.262 T 23-10-2018 IPR033747 Class I PurE STK_08060 d4145c85879871a2da046fd5966390eb 157 Gene3D G3DSA:3.40.50.7700 1 157 8.3E-72 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 STK_08060 d4145c85879871a2da046fd5966390eb 157 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 4 154 1.2E-69 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 STK_08060 d4145c85879871a2da046fd5966390eb 157 SMART SM01001 2 151 7.1E-102 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 STK_08060 d4145c85879871a2da046fd5966390eb 157 SUPERFAMILY SSF52255 2 154 4.06E-67 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 STK_08060 d4145c85879871a2da046fd5966390eb 157 Pfam PF00731 AIR carboxylase 3 148 7.9E-68 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 STK_16550 e3fad61034b6904fd3eb83dbca3d9e80 383 Pfam PF02589 LUD domain 52 283 6.8E-54 T 23-10-2018 IPR003741 LUD domain STK_16550 e3fad61034b6904fd3eb83dbca3d9e80 383 Gene3D G3DSA:3.40.50.10420 102 284 2.5E-29 T 23-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily STK_16550 e3fad61034b6904fd3eb83dbca3d9e80 383 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 302 313 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_16550 e3fad61034b6904fd3eb83dbca3d9e80 383 Pfam PF13183 4Fe-4S dicluster domain 300 363 3.2E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_16550 e3fad61034b6904fd3eb83dbca3d9e80 383 SUPERFAMILY SSF100950 47 284 2.68E-46 T 23-10-2018 IPR037171 NagB/RpiA transferase-like STK_16550 e3fad61034b6904fd3eb83dbca3d9e80 383 Gene3D G3DSA:1.10.1060.10 287 383 4.3E-5 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 STK_16550 e3fad61034b6904fd3eb83dbca3d9e80 383 SUPERFAMILY SSF46548 289 374 7.85E-15 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 STK_04415 d1f9ef5c59df9d65110754005c7a4229 70 Gene3D G3DSA:2.20.25.30 7 70 6.3E-24 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_04415 d1f9ef5c59df9d65110754005c7a4229 70 Hamap MF_00327 50S ribosomal protein L37Ae [rpl37ae]. 1 70 22.553 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_04415 d1f9ef5c59df9d65110754005c7a4229 70 Pfam PF01780 Ribosomal L37ae protein family 3 69 4.1E-25 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_04415 d1f9ef5c59df9d65110754005c7a4229 70 SUPERFAMILY SSF57829 7 69 1.83E-21 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 STK_17470 e55269c519a40f9d52c0449ff201c7b5 126 Gene3D G3DSA:1.20.120.330 8 126 2.0E-34 T 23-10-2018 STK_17470 e55269c519a40f9d52c0449ff201c7b5 126 Pfam PF05942 Archaeal PaREP1/PaREP8 family 10 116 1.1E-27 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_18160 a1a6d8cd6067557fc10f10267c175ed7 331 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 212 1.7E-44 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 STK_18160 a1a6d8cd6067557fc10f10267c175ed7 331 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 23-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 STK_18160 a1a6d8cd6067557fc10f10267c175ed7 331 SUPERFAMILY SSF53790 2 241 1.96E-66 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 STK_18160 a1a6d8cd6067557fc10f10267c175ed7 331 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 3 234 3.4E-57 T 23-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 STK_18160 a1a6d8cd6067557fc10f10267c175ed7 331 Gene3D G3DSA:3.30.950.10 113 235 7.4E-40 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 STK_18160 a1a6d8cd6067557fc10f10267c175ed7 331 Gene3D G3DSA:3.40.1010.10 1 112 3.9E-34 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 STK_18160 a1a6d8cd6067557fc10f10267c175ed7 331 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 78 111 - T 23-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 STK_18160 a1a6d8cd6067557fc10f10267c175ed7 331 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 5 256 8.5E-96 T 23-10-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 STK_24170 14f528d3a38a619e9f23a3a97e13bfe6 250 SUPERFAMILY SSF52096 4 249 5.84E-64 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily STK_24170 14f528d3a38a619e9f23a3a97e13bfe6 250 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 249 5.4E-48 T 23-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 STK_24170 14f528d3a38a619e9f23a3a97e13bfe6 250 Gene3D G3DSA:3.90.226.10 1 191 4.5E-47 T 23-10-2018 STK_24170 14f528d3a38a619e9f23a3a97e13bfe6 250 Gene3D G3DSA:1.10.12.10 193 250 9.8E-22 T 23-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal STK_24170 14f528d3a38a619e9f23a3a97e13bfe6 250 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 96 116 - T 23-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 STK_09680 684d3824f3ea0ccc55fc32d872cf6148 228 SUPERFAMILY SSF53448 1 221 5.63E-64 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_09680 684d3824f3ea0ccc55fc32d872cf6148 228 Gene3D G3DSA:3.90.550.10 1 223 8.6E-67 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_09680 684d3824f3ea0ccc55fc32d872cf6148 228 Pfam PF00483 Nucleotidyl transferase 2 221 2.9E-34 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 STK_09460 246b8f8ee330202e44747dbdc7d00464 291 SUPERFAMILY SSF53271 66 278 1.07E-38 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like STK_09460 246b8f8ee330202e44747dbdc7d00464 291 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 291 3.1E-87 T 23-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 STK_09460 246b8f8ee330202e44747dbdc7d00464 291 Hamap MF_00583_A Putative ribose-phosphate pyrophosphokinase [prs]. 2 286 39.156 T 23-10-2018 IPR037514 Ribose-phosphate pyrophosphokinase, archaea GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 STK_09460 246b8f8ee330202e44747dbdc7d00464 291 Gene3D G3DSA:3.40.50.2020 13 143 2.0E-85 T 23-10-2018 STK_09460 246b8f8ee330202e44747dbdc7d00464 291 SMART SM01400 1 117 3.0E-38 T 23-10-2018 STK_09460 246b8f8ee330202e44747dbdc7d00464 291 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 1 117 5.6E-26 T 23-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 STK_09460 246b8f8ee330202e44747dbdc7d00464 291 Gene3D G3DSA:3.40.50.2020 144 271 2.0E-85 T 23-10-2018 STK_09460 246b8f8ee330202e44747dbdc7d00464 291 Pfam PF00156 Phosphoribosyl transferase domain 148 273 1.3E-21 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 STK_08070 e97de524393514ff6a4c9479c3fd59e0 364 Pfam PF02222 ATP-grasp domain 109 272 1.7E-49 T 23-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type STK_08070 e97de524393514ff6a4c9479c3fd59e0 364 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 10 349 3.7E-119 T 23-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 STK_08070 e97de524393514ff6a4c9479c3fd59e0 364 Gene3D G3DSA:3.40.50.20 8 99 2.0E-25 T 23-10-2018 STK_08070 e97de524393514ff6a4c9479c3fd59e0 364 SUPERFAMILY SSF52440 4 97 7.91E-18 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily STK_08070 e97de524393514ff6a4c9479c3fd59e0 364 Gene3D G3DSA:3.30.470.20 179 360 2.1E-57 T 23-10-2018 STK_08070 e97de524393514ff6a4c9479c3fd59e0 364 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 10 343 35.218 T 23-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 STK_08070 e97de524393514ff6a4c9479c3fd59e0 364 Gene3D G3DSA:3.30.1490.20 100 178 1.6E-17 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 STK_08070 e97de524393514ff6a4c9479c3fd59e0 364 SUPERFAMILY SSF56059 101 292 7.25E-49 T 23-10-2018 STK_08070 e97de524393514ff6a4c9479c3fd59e0 364 SUPERFAMILY SSF51246 297 359 1.96E-13 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 STK_04800 a24ececa17b6ee6d210334d81c9c49f8 334 SUPERFAMILY SSF51735 141 306 8.2E-34 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_04800 a24ececa17b6ee6d210334d81c9c49f8 334 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 132 1.5E-26 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 STK_04800 a24ececa17b6ee6d210334d81c9c49f8 334 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 164 185 - T 23-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 STK_04800 a24ececa17b6ee6d210334d81c9c49f8 334 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 23-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 STK_04800 a24ececa17b6ee6d210334d81c9c49f8 334 Gene3D G3DSA:3.90.180.10 1 334 2.8E-96 T 23-10-2018 STK_04800 a24ececa17b6ee6d210334d81c9c49f8 334 SUPERFAMILY SSF50129 1 168 3.8E-48 T 23-10-2018 IPR011032 GroES-like superfamily STK_04800 a24ececa17b6ee6d210334d81c9c49f8 334 SMART SM00829 8 332 7.6E-13 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 STK_04800 a24ececa17b6ee6d210334d81c9c49f8 334 Pfam PF00107 Zinc-binding dehydrogenase 175 295 2.9E-22 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 STK_24980 67af6e33f415d64fac6d99f716f8731c 419 SUPERFAMILY SSF56349 131 412 1.06E-25 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 STK_24980 67af6e33f415d64fac6d99f716f8731c 419 SMART SM00530 17 69 0.0014 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 STK_24980 67af6e33f415d64fac6d99f716f8731c 419 Pfam PF01381 Helix-turn-helix 18 66 1.6E-5 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 STK_24980 67af6e33f415d64fac6d99f716f8731c 419 Pfam PF00589 Phage integrase family 227 385 5.8E-14 T 23-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 STK_09390 3dc0b6f3211648abee830bae1381237c 709 SMART SM00060 399 475 3.9E-5 T 23-10-2018 IPR003961 Fibronectin type III GO:0005515 STK_09390 3dc0b6f3211648abee830bae1381237c 709 SMART SM00060 315 389 1.4E-4 T 23-10-2018 IPR003961 Fibronectin type III GO:0005515 STK_09390 3dc0b6f3211648abee830bae1381237c 709 SMART SM00060 568 634 110.0 T 23-10-2018 IPR003961 Fibronectin type III GO:0005515 STK_09390 3dc0b6f3211648abee830bae1381237c 709 Pfam PF13964 Kelch motif 133 179 4.9E-7 T 23-10-2018 STK_09390 3dc0b6f3211648abee830bae1381237c 709 SMART SM00612 49 94 0.011 T 23-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 STK_09390 3dc0b6f3211648abee830bae1381237c 709 SMART SM00612 95 140 8.1 T 23-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 STK_09390 3dc0b6f3211648abee830bae1381237c 709 SMART SM00612 141 191 0.17 T 23-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 STK_09390 3dc0b6f3211648abee830bae1381237c 709 SMART SM00612 193 240 5.1E-6 T 23-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 STK_09390 3dc0b6f3211648abee830bae1381237c 709 Gene3D G3DSA:2.120.10.80 112 313 3.3E-26 T 23-10-2018 IPR015915 Kelch-type beta propeller GO:0005515 STK_09390 3dc0b6f3211648abee830bae1381237c 709 Pfam PF00041 Fibronectin type III domain 316 392 5.3E-6 T 23-10-2018 IPR003961 Fibronectin type III GO:0005515 STK_09390 3dc0b6f3211648abee830bae1381237c 709 Gene3D G3DSA:2.120.10.80 25 111 2.0E-12 T 23-10-2018 IPR015915 Kelch-type beta propeller GO:0005515 STK_09390 3dc0b6f3211648abee830bae1381237c 709 Gene3D G3DSA:2.60.40.10 314 398 1.0E-10 T 23-10-2018 IPR013783 Immunoglobulin-like fold STK_09390 3dc0b6f3211648abee830bae1381237c 709 Pfam PF01344 Kelch motif 39 81 1.4E-4 T 23-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 STK_09390 3dc0b6f3211648abee830bae1381237c 709 Pfam PF01344 Kelch motif 193 227 3.8E-6 T 23-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 STK_09390 3dc0b6f3211648abee830bae1381237c 709 SUPERFAMILY SSF49265 317 483 2.63E-20 T 23-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 STK_09390 3dc0b6f3211648abee830bae1381237c 709 Gene3D G3DSA:2.60.40.10 399 489 9.4E-11 T 23-10-2018 IPR013783 Immunoglobulin-like fold STK_09390 3dc0b6f3211648abee830bae1381237c 709 SUPERFAMILY SSF50965 33 318 5.49E-33 T 23-10-2018 IPR011043 Galactose oxidase/kelch, beta-propeller STK_13490 016f96dffe55a483a62559a26e67bf5e 348 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 219 299 2.9E-10 T 23-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 STK_13490 016f96dffe55a483a62559a26e67bf5e 348 Gene3D G3DSA:3.40.47.10 2 347 1.5E-73 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_13490 016f96dffe55a483a62559a26e67bf5e 348 TIGRFAM TIGR00748 HMG_CoA_syn_Arc: putative hydroxymethylglutaryl-CoA synthase 3 346 5.9E-139 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related STK_13490 016f96dffe55a483a62559a26e67bf5e 348 Hamap MF_01409 UPF0219 protein . 2 346 57.59 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related STK_13490 016f96dffe55a483a62559a26e67bf5e 348 SUPERFAMILY SSF53901 171 345 3.84E-45 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_13490 016f96dffe55a483a62559a26e67bf5e 348 SUPERFAMILY SSF53901 4 167 3.67E-33 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_21470 b0a6cd1fa834ff9a840a2dec14fd71a0 226 Gene3D G3DSA:3.40.50.1000 2 206 4.8E-35 T 23-10-2018 IPR023214 HAD superfamily STK_21470 b0a6cd1fa834ff9a840a2dec14fd71a0 226 SUPERFAMILY SSF56784 1 212 1.78E-33 T 23-10-2018 IPR036412 HAD-like superfamily STK_21470 b0a6cd1fa834ff9a840a2dec14fd71a0 226 Pfam PF08282 haloacid dehalogenase-like hydrolase 2 111 4.6E-5 T 23-10-2018 STK_21470 b0a6cd1fa834ff9a840a2dec14fd71a0 226 Pfam PF08282 haloacid dehalogenase-like hydrolase 130 208 6.8E-17 T 23-10-2018 STK_21470 b0a6cd1fa834ff9a840a2dec14fd71a0 226 Hamap MF_01419 Phosphoglycolate phosphatase. 1 213 23.974 T 23-10-2018 IPR006382 Phosphoglycolate phosphatase GO:0000287|GO:0008967|GO:0016311 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 STK_21470 b0a6cd1fa834ff9a840a2dec14fd71a0 226 Gene3D G3DSA:3.90.1070.10 78 138 4.8E-35 T 23-10-2018 STK_21470 b0a6cd1fa834ff9a840a2dec14fd71a0 226 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 2 208 7.0E-43 T 23-10-2018 STK_21470 b0a6cd1fa834ff9a840a2dec14fd71a0 226 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 1 181 2.9E-17 T 23-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 STK_21470 b0a6cd1fa834ff9a840a2dec14fd71a0 226 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 2 211 4.5E-39 T 23-10-2018 STK_12710 36f8d3dacaa064ccf40db60235cf9151 295 SUPERFAMILY SSF47954 104 194 9.45E-16 T 23-10-2018 IPR036915 Cyclin-like superfamily STK_12710 36f8d3dacaa064ccf40db60235cf9151 295 Pfam PF08271 TFIIB zinc-binding 5 45 1.8E-17 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type STK_12710 36f8d3dacaa064ccf40db60235cf9151 295 SMART SM00385 206 287 6.1E-6 T 23-10-2018 IPR013763 Cyclin-like STK_12710 36f8d3dacaa064ccf40db60235cf9151 295 SUPERFAMILY SSF47954 202 292 6.8E-24 T 23-10-2018 IPR036915 Cyclin-like superfamily STK_12710 36f8d3dacaa064ccf40db60235cf9151 295 Gene3D G3DSA:1.10.472.10 203 295 8.0E-22 T 23-10-2018 STK_12710 36f8d3dacaa064ccf40db60235cf9151 295 Pfam PF00382 Transcription factor TFIIB repeat 208 278 6.3E-15 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 STK_12710 36f8d3dacaa064ccf40db60235cf9151 295 Pfam PF00382 Transcription factor TFIIB repeat 115 180 8.6E-7 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 STK_12710 36f8d3dacaa064ccf40db60235cf9151 295 SUPERFAMILY SSF57783 2 49 7.94E-16 T 23-10-2018 STK_12710 36f8d3dacaa064ccf40db60235cf9151 295 Gene3D G3DSA:1.10.472.170 4 192 9.5E-46 T 23-10-2018 STK_12710 36f8d3dacaa064ccf40db60235cf9151 295 PRINTS PR00685 Transcription initiation factor IIB signature 151 170 3.9E-34 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 STK_12710 36f8d3dacaa064ccf40db60235cf9151 295 PRINTS PR00685 Transcription initiation factor IIB signature 273 287 3.9E-34 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 STK_12710 36f8d3dacaa064ccf40db60235cf9151 295 PRINTS PR00685 Transcription initiation factor IIB signature 18 38 3.9E-34 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 STK_12710 36f8d3dacaa064ccf40db60235cf9151 295 PRINTS PR00685 Transcription initiation factor IIB signature 40 53 3.9E-34 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 STK_12710 36f8d3dacaa064ccf40db60235cf9151 295 PRINTS PR00685 Transcription initiation factor IIB signature 53 74 3.9E-34 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 STK_12710 36f8d3dacaa064ccf40db60235cf9151 295 PRINTS PR00685 Transcription initiation factor IIB signature 207 225 3.9E-34 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 STK_12710 36f8d3dacaa064ccf40db60235cf9151 295 PRINTS PR00685 Transcription initiation factor IIB signature 241 257 3.9E-34 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 STK_13780 9f890b5232eac418bfbdf8cbd2c5f469 334 Pfam PF05167 Uncharacterised ACR (DUF711) 168 317 3.2E-26 T 23-10-2018 IPR007841 Uncharacterised protein family UPF0210 STK_13780 9f890b5232eac418bfbdf8cbd2c5f469 334 Gene3D G3DSA:3.20.70.20 158 333 2.7E-36 T 23-10-2018 STK_13780 9f890b5232eac418bfbdf8cbd2c5f469 334 SUPERFAMILY SSF51998 1 333 5.77E-69 T 23-10-2018 STK_13780 9f890b5232eac418bfbdf8cbd2c5f469 334 PIRSF PIRSF027893 1 333 6.7E-162 T 23-10-2018 IPR014537 Uncharacterised conserved protein UCP027893 STK_24750 e37a6ae1185c6fab26c147d24213ff14 988 Pfam PF05317 Thermopsin 32 269 1.0E-47 T 23-10-2018 IPR007981 Peptidase A5, thermopsin STK_12320 3997bfec9c90c5a7512d46a90a96aa90 245 SUPERFAMILY SSF51366 3 241 1.13E-53 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 STK_12320 3997bfec9c90c5a7512d46a90a96aa90 245 Gene3D G3DSA:3.20.20.70 1 244 2.2E-48 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_12320 3997bfec9c90c5a7512d46a90a96aa90 245 Pfam PF00290 Tryptophan synthase alpha chain 2 230 2.7E-34 T 23-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 STK_12320 3997bfec9c90c5a7512d46a90a96aa90 245 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 1 240 24.007 T 23-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 STK_12320 3997bfec9c90c5a7512d46a90a96aa90 245 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 3 225 2.6E-33 T 23-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 STK_12320 3997bfec9c90c5a7512d46a90a96aa90 245 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 34 47 - T 23-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 STK_07920 6b0f5e229dccb93eb5c97d6ada68b154 122 Pfam PF05168 HEPN domain 1 118 6.3E-27 T 23-10-2018 IPR007842 HEPN domain STK_07920 6b0f5e229dccb93eb5c97d6ada68b154 122 SUPERFAMILY SSF81593 3 117 7.85E-26 T 23-10-2018 STK_07920 6b0f5e229dccb93eb5c97d6ada68b154 122 SMART SM00748 5 115 4.8E-37 T 23-10-2018 IPR007842 HEPN domain STK_07920 6b0f5e229dccb93eb5c97d6ada68b154 122 Gene3D G3DSA:1.20.120.330 2 120 9.5E-21 T 23-10-2018 STK_09450 8db30885fb55ab1c71e691e0b81c245d 254 SUPERFAMILY SSF52540 3 237 5.03E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_09450 8db30885fb55ab1c71e691e0b81c245d 254 Pfam PF03029 Conserved hypothetical ATP binding protein 6 238 7.0E-55 T 23-10-2018 IPR004130 GPN-loop GTPase STK_09450 8db30885fb55ab1c71e691e0b81c245d 254 Gene3D G3DSA:3.40.50.300 1 241 4.7E-62 T 23-10-2018 STK_21890 f7cdb572c63e144e3863d4d58a496eaa 114 Hamap MF_00814 Nascent polypeptide-associated complex protein [nac]. 6 110 18.711 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 STK_21890 f7cdb572c63e144e3863d4d58a496eaa 114 Gene3D G3DSA:2.20.70.30 10 68 6.2E-14 T 23-10-2018 IPR038187 NAC A/B domain superfamily STK_21890 f7cdb572c63e144e3863d4d58a496eaa 114 SUPERFAMILY SSF46934 71 110 1.87E-8 T 23-10-2018 IPR009060 UBA-like superfamily GO:0005515 STK_21890 f7cdb572c63e144e3863d4d58a496eaa 114 SMART SM01407 5 63 3.9E-14 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain STK_21890 f7cdb572c63e144e3863d4d58a496eaa 114 Pfam PF01849 NAC domain 12 62 9.5E-10 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain STK_21890 f7cdb572c63e144e3863d4d58a496eaa 114 Gene3D G3DSA:1.10.8.10 71 110 5.1E-15 T 23-10-2018 STK_08920 83eb79d87eaf2dd3bcf6a4d1a7a77e76 223 Pfam PF07690 Major Facilitator Superfamily 13 207 1.6E-9 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_08920 83eb79d87eaf2dd3bcf6a4d1a7a77e76 223 SUPERFAMILY SSF103473 4 205 1.05E-20 T 23-10-2018 IPR036259 MFS transporter superfamily STK_08920 83eb79d87eaf2dd3bcf6a4d1a7a77e76 223 Gene3D G3DSA:1.20.1250.20 2 219 7.8E-22 T 23-10-2018 STK_22740 c715e4d048cbb99d2a7ac90ef8853fde 390 PIRSF PIRSF001456 3 373 7.6E-141 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 STK_22740 c715e4d048cbb99d2a7ac90ef8853fde 390 Pfam PF01264 Chorismate synthase 10 354 7.9E-126 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 STK_22740 c715e4d048cbb99d2a7ac90ef8853fde 390 ProSitePatterns PS00789 Chorismate synthase signature 3. 328 344 - T 23-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 STK_22740 c715e4d048cbb99d2a7ac90ef8853fde 390 Hamap MF_00300 Chorismate synthase [aroC]. 10 361 35.819 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 STK_22740 c715e4d048cbb99d2a7ac90ef8853fde 390 SUPERFAMILY SSF103263 4 358 2.35E-125 T 23-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 STK_22740 c715e4d048cbb99d2a7ac90ef8853fde 390 TIGRFAM TIGR00033 aroC: chorismate synthase 10 355 4.4E-124 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 STK_22740 c715e4d048cbb99d2a7ac90ef8853fde 390 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 23-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 STK_22740 c715e4d048cbb99d2a7ac90ef8853fde 390 Gene3D G3DSA:3.60.150.10 1 367 9.0E-134 T 23-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 STK_18610 98d0beee6c87dd9f969e8dc055d3b776 500 Pfam PF00571 CBS domain 453 496 0.0048 T 23-10-2018 IPR000644 CBS domain STK_18610 98d0beee6c87dd9f969e8dc055d3b776 500 Pfam PF00571 CBS domain 387 432 7.8E-7 T 23-10-2018 IPR000644 CBS domain STK_18610 98d0beee6c87dd9f969e8dc055d3b776 500 Gene3D G3DSA:1.20.1530.20 5 370 1.9E-39 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily STK_18610 98d0beee6c87dd9f969e8dc055d3b776 500 SMART SM00116 386 434 0.99 T 23-10-2018 IPR000644 CBS domain STK_18610 98d0beee6c87dd9f969e8dc055d3b776 500 SMART SM00116 449 497 4.4 T 23-10-2018 IPR000644 CBS domain STK_18610 98d0beee6c87dd9f969e8dc055d3b776 500 SUPERFAMILY SSF54631 383 496 1.83E-15 T 23-10-2018 STK_18610 98d0beee6c87dd9f969e8dc055d3b776 500 Gene3D G3DSA:3.10.580.10 380 498 1.6E-15 T 23-10-2018 STK_18610 98d0beee6c87dd9f969e8dc055d3b776 500 Pfam PF00999 Sodium/hydrogen exchanger family 11 359 5.4E-32 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 STK_02890 5d62915c7721753e3b5121432ba80463 333 SUPERFAMILY SSF56059 105 333 1.08E-82 T 23-10-2018 STK_02890 5d62915c7721753e3b5121432ba80463 333 Hamap MF_01163 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [purP]. 1 333 50.665 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 STK_02890 5d62915c7721753e3b5121432ba80463 333 Gene3D G3DSA:3.40.50.20 1 89 2.2E-28 T 23-10-2018 STK_02890 5d62915c7721753e3b5121432ba80463 333 Pfam PF06849 Protein of unknown function (DUF1246) 3 121 2.1E-41 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 STK_02890 5d62915c7721753e3b5121432ba80463 333 Gene3D G3DSA:3.30.1490.20 118 179 8.7E-96 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 STK_02890 5d62915c7721753e3b5121432ba80463 333 Gene3D G3DSA:3.30.470.20 90 331 8.7E-96 T 23-10-2018 STK_02890 5d62915c7721753e3b5121432ba80463 333 PIRSF PIRSF004602 1 333 1.2E-135 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 STK_02890 5d62915c7721753e3b5121432ba80463 333 Pfam PF06973 Domain of unknown function (DUF1297) 153 333 4.4E-76 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 STK_02890 5d62915c7721753e3b5121432ba80463 333 SUPERFAMILY SSF52440 3 102 6.71E-32 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily STK_14640 d77e487d14e907ef25ef3780a32a9865 394 PRINTS PR00083 Histidinol dehydrogenase signature 328 346 4.2E-85 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 STK_14640 d77e487d14e907ef25ef3780a32a9865 394 PRINTS PR00083 Histidinol dehydrogenase signature 182 207 4.2E-85 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 STK_14640 d77e487d14e907ef25ef3780a32a9865 394 PRINTS PR00083 Histidinol dehydrogenase signature 21 45 4.2E-85 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 STK_14640 d77e487d14e907ef25ef3780a32a9865 394 PRINTS PR00083 Histidinol dehydrogenase signature 211 232 4.2E-85 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 STK_14640 d77e487d14e907ef25ef3780a32a9865 394 PRINTS PR00083 Histidinol dehydrogenase signature 233 252 4.2E-85 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 STK_14640 d77e487d14e907ef25ef3780a32a9865 394 PRINTS PR00083 Histidinol dehydrogenase signature 152 178 4.2E-85 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 STK_14640 d77e487d14e907ef25ef3780a32a9865 394 PRINTS PR00083 Histidinol dehydrogenase signature 120 146 4.2E-85 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 STK_14640 d77e487d14e907ef25ef3780a32a9865 394 PRINTS PR00083 Histidinol dehydrogenase signature 288 313 4.2E-85 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 STK_14640 d77e487d14e907ef25ef3780a32a9865 394 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 21 392 1.5E-124 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 STK_14640 d77e487d14e907ef25ef3780a32a9865 394 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 4 393 35.969 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 STK_14640 d77e487d14e907ef25ef3780a32a9865 394 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 211 243 - T 23-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 STK_14640 d77e487d14e907ef25ef3780a32a9865 394 Gene3D G3DSA:3.40.50.1980 19 214 3.3E-94 T 23-10-2018 STK_14640 d77e487d14e907ef25ef3780a32a9865 394 SUPERFAMILY SSF53720 15 364 2.35E-52 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 STK_14640 d77e487d14e907ef25ef3780a32a9865 394 PIRSF PIRSF000099 1 394 2.9E-133 T 23-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 STK_14640 d77e487d14e907ef25ef3780a32a9865 394 Pfam PF00815 Histidinol dehydrogenase 10 392 2.0E-126 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 STK_14640 d77e487d14e907ef25ef3780a32a9865 394 Gene3D G3DSA:3.40.50.1980 215 316 3.3E-94 T 23-10-2018 STK_10120 233e6d84adf4da26a6df03b2aac448e5 505 PIRSF PIRSF006060 1 503 1.0E-32 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_10120 233e6d84adf4da26a6df03b2aac448e5 505 Pfam PF13520 Amino acid permease 28 485 3.8E-24 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_10120 233e6d84adf4da26a6df03b2aac448e5 505 Gene3D G3DSA:1.20.1740.10 14 497 6.8E-17 T 23-10-2018 STK_12970 445906dc5b984f2b5235b7d804eaa207 445 SMART SM00963 1 81 7.1E-16 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 STK_12970 445906dc5b984f2b5235b7d804eaa207 445 SUPERFAMILY SSF47364 3 85 3.53E-16 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 STK_12970 445906dc5b984f2b5235b7d804eaa207 445 Gene3D G3DSA:1.20.120.140 3 302 1.2E-110 T 23-10-2018 STK_12970 445906dc5b984f2b5235b7d804eaa207 445 Gene3D G3DSA:3.40.50.300 85 281 1.2E-110 T 23-10-2018 STK_12970 445906dc5b984f2b5235b7d804eaa207 445 SMART SM00962 95 292 5.0E-104 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 STK_12970 445906dc5b984f2b5235b7d804eaa207 445 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 1 439 36.17 T 23-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 STK_12970 445906dc5b984f2b5235b7d804eaa207 445 Pfam PF02881 SRP54-type protein, helical bundle domain 3 77 1.3E-13 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 STK_12970 445906dc5b984f2b5235b7d804eaa207 445 SUPERFAMILY SSF52540 92 294 1.56E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_12970 445906dc5b984f2b5235b7d804eaa207 445 SUPERFAMILY SSF47446 294 429 8.24E-42 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 STK_12970 445906dc5b984f2b5235b7d804eaa207 445 Gene3D G3DSA:1.10.260.30 303 430 4.2E-44 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 STK_12970 445906dc5b984f2b5235b7d804eaa207 445 SMART SM00382 94 297 2.6E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_12970 445906dc5b984f2b5235b7d804eaa207 445 Pfam PF00448 SRP54-type protein, GTPase domain 96 292 1.2E-72 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 STK_12970 445906dc5b984f2b5235b7d804eaa207 445 Pfam PF02978 Signal peptide binding domain 326 424 4.2E-30 T 23-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 STK_02310 74c5d41a3cd4bc1a5ded685a803318d8 595 Pfam PF05670 Domain of unknown function (DUF814) 395 495 1.1E-28 T 23-10-2018 IPR008532 Domain of unknown function DUF814 STK_02310 74c5d41a3cd4bc1a5ded685a803318d8 595 Gene3D G3DSA:2.30.310.10 6 153 1.1E-11 T 23-10-2018 STK_02310 74c5d41a3cd4bc1a5ded685a803318d8 595 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 9 374 3.7E-31 T 23-10-2018 STK_26045 434d7ad5d34898046fd72d1fcde49c68 87 Gene3D G3DSA:3.30.70.100 3 77 8.8E-12 T 23-10-2018 STK_26045 434d7ad5d34898046fd72d1fcde49c68 87 Pfam PF00403 Heavy-metal-associated domain 6 68 2.7E-9 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 STK_26045 434d7ad5d34898046fd72d1fcde49c68 87 SUPERFAMILY SSF55008 1 67 4.84E-10 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 STK_21590 37d9c8438dd2f5e679f4b5685eaf4c5e 279 Gene3D G3DSA:3.40.50.620 10 263 2.4E-76 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_21590 37d9c8438dd2f5e679f4b5685eaf4c5e 279 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 13 261 48.353 T 23-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 STK_21590 37d9c8438dd2f5e679f4b5685eaf4c5e 279 SUPERFAMILY SSF52402 5 258 4.19E-71 T 23-10-2018 STK_21590 37d9c8438dd2f5e679f4b5685eaf4c5e 279 Pfam PF02540 NAD synthase 19 258 2.3E-74 T 23-10-2018 IPR022310 NAD/GMP synthase STK_21590 37d9c8438dd2f5e679f4b5685eaf4c5e 279 TIGRFAM TIGR00552 nadE: NAD+ synthetase 16 261 7.9E-73 T 23-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 STK_10210 759081107b218589ab29d1b56608d529 312 SUPERFAMILY SSF50022 2 114 3.67E-30 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 STK_10210 759081107b218589ab29d1b56608d529 312 Pfam PF00355 Rieske [2Fe-2S] domain 4 81 9.1E-19 T 23-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 STK_10210 759081107b218589ab29d1b56608d529 312 Gene3D G3DSA:2.102.10.10 1 123 1.7E-30 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 STK_10210 759081107b218589ab29d1b56608d529 312 SUPERFAMILY SSF55961 112 306 2.2E-26 T 23-10-2018 STK_10210 759081107b218589ab29d1b56608d529 312 Gene3D G3DSA:3.30.530.90 124 306 3.4E-10 T 23-10-2018 STK_02620 ef4558d7bfbf15dc0c973e460acad21e 299 SUPERFAMILY SSF53067 1 208 3.88E-5 T 23-10-2018 STK_02620 ef4558d7bfbf15dc0c973e460acad21e 299 Pfam PF07318 Protein of unknown function (DUF1464) 5 287 1.3E-109 T 23-10-2018 IPR009927 Protein of unknown function DUF1464 STK_02620 ef4558d7bfbf15dc0c973e460acad21e 299 PIRSF PIRSF009433 1 299 1.0E-109 T 23-10-2018 IPR009927 Protein of unknown function DUF1464 STK_13680 dba60f017156276a60a44f79b409dbea 170 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 137 1.1E-17 T 23-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 STK_13680 dba60f017156276a60a44f79b409dbea 170 SUPERFAMILY SSF54747 4 81 3.79E-22 T 23-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily STK_13680 dba60f017156276a60a44f79b409dbea 170 Gene3D G3DSA:2.10.260.30 3 69 4.5E-25 T 23-10-2018 STK_13680 dba60f017156276a60a44f79b409dbea 170 ProSitePatterns PS00359 Ribosomal protein L11 signature. 124 138 - T 23-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_13680 dba60f017156276a60a44f79b409dbea 170 SUPERFAMILY SSF46906 66 138 1.44E-18 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily STK_13680 dba60f017156276a60a44f79b409dbea 170 Gene3D G3DSA:1.10.10.250 73 164 2.4E-28 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily STK_13680 dba60f017156276a60a44f79b409dbea 170 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 2 139 24.125 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 STK_13680 dba60f017156276a60a44f79b409dbea 170 SMART SM00649 6 138 6.6E-54 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 STK_13680 dba60f017156276a60a44f79b409dbea 170 Pfam PF03946 Ribosomal protein L11, N-terminal domain 6 61 7.3E-20 T 23-10-2018 IPR020784 Ribosomal protein L11, N-terminal STK_14730 46a482803e723bff001c9e900c997b5c 155 SUPERFAMILY SSF54909 69 152 4.56E-17 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel STK_14730 46a482803e723bff001c9e900c997b5c 155 Gene3D G3DSA:3.30.70.920 62 155 2.0E-21 T 23-10-2018 STK_14730 46a482803e723bff001c9e900c997b5c 155 SUPERFAMILY SSF46785 9 69 6.83E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_14730 46a482803e723bff001c9e900c997b5c 155 Pfam PF13412 Winged helix-turn-helix DNA-binding 10 56 7.4E-10 T 23-10-2018 STK_14730 46a482803e723bff001c9e900c997b5c 155 Gene3D G3DSA:1.10.10.10 1 61 4.1E-15 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_14730 46a482803e723bff001c9e900c997b5c 155 Pfam PF01037 Lrp/AsnC ligand binding domain 76 144 1.3E-17 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain STK_14730 46a482803e723bff001c9e900c997b5c 155 SMART SM00344 9 115 9.9E-36 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 STK_14730 46a482803e723bff001c9e900c997b5c 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 36 55 1.9E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_14730 46a482803e723bff001c9e900c997b5c 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 25 36 1.9E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_14730 46a482803e723bff001c9e900c997b5c 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 9 25 1.9E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_07200 794b2646aaea1b80e6eb5d5fdde51e9d 391 SMART SM00418 4 77 0.0022 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 STK_07200 794b2646aaea1b80e6eb5d5fdde51e9d 391 Pfam PF12840 Helix-turn-helix domain 6 58 3.7E-8 T 23-10-2018 STK_07200 794b2646aaea1b80e6eb5d5fdde51e9d 391 Gene3D G3DSA:1.10.10.10 2 75 1.5E-15 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_07200 794b2646aaea1b80e6eb5d5fdde51e9d 391 SUPERFAMILY SSF46785 4 70 1.46E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_03280 077a6cc5a47062c0b6ad2cca9f1ec134 240 SUPERFAMILY SSF159659 5 227 7.32E-34 T 23-10-2018 STK_03280 077a6cc5a47062c0b6ad2cca9f1ec134 240 Gene3D G3DSA:3.40.50.10900 2 239 5.4E-44 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily STK_03280 077a6cc5a47062c0b6ad2cca9f1ec134 240 Pfam PF09754 PAC2 family 20 222 1.1E-35 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 STK_06230 f760782f4c58eda58b42c3a5739bdc3b 781 Gene3D G3DSA:2.60.40.1730 2 175 9.4E-45 T 23-10-2018 STK_06230 f760782f4c58eda58b42c3a5739bdc3b 781 Gene3D G3DSA:2.60.40.1910 423 500 4.3E-19 T 23-10-2018 STK_06230 f760782f4c58eda58b42c3a5739bdc3b 781 SUPERFAMILY SSF63737 4 173 2.75E-40 T 23-10-2018 STK_06230 f760782f4c58eda58b42c3a5739bdc3b 781 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 269 284 2.4E-26 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 STK_06230 f760782f4c58eda58b42c3a5739bdc3b 781 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 288 300 2.4E-26 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 STK_06230 f760782f4c58eda58b42c3a5739bdc3b 781 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 110 125 2.4E-26 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 STK_06230 f760782f4c58eda58b42c3a5739bdc3b 781 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 157 172 2.4E-26 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 STK_06230 f760782f4c58eda58b42c3a5739bdc3b 781 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 234 244 2.4E-26 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 STK_06230 f760782f4c58eda58b42c3a5739bdc3b 781 Pfam PF01433 Peptidase family M1 domain 185 417 1.0E-86 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 STK_06230 f760782f4c58eda58b42c3a5739bdc3b 781 Gene3D G3DSA:1.10.390.60 180 422 6.6E-100 T 23-10-2018 STK_06230 f760782f4c58eda58b42c3a5739bdc3b 781 Pfam PF11838 ERAP1-like C-terminal domain 486 772 9.9E-31 T 23-10-2018 IPR024571 ERAP1-like C-terminal domain STK_06230 f760782f4c58eda58b42c3a5739bdc3b 781 Gene3D G3DSA:1.25.50.20 501 775 1.5E-26 T 23-10-2018 STK_06230 f760782f4c58eda58b42c3a5739bdc3b 781 SUPERFAMILY SSF55486 184 428 6.89E-87 T 23-10-2018 STK_14650 ab4c5f8c69abd96a7e52a5befb1dd405 94 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 6 89 1.8E-30 T 23-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 STK_14650 ab4c5f8c69abd96a7e52a5befb1dd405 94 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 3 89 21.56 T 23-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 STK_14650 ab4c5f8c69abd96a7e52a5befb1dd405 94 SUPERFAMILY SSF101386 4 93 2.8E-26 T 23-10-2018 STK_14650 ab4c5f8c69abd96a7e52a5befb1dd405 94 Gene3D G3DSA:1.10.287.1080 2 94 9.5E-30 T 23-10-2018 STK_14650 ab4c5f8c69abd96a7e52a5befb1dd405 94 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 8 92 3.2E-16 T 23-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 STK_01130 a3e66053ff731e0d3a1d78d02dc91c7e 153 SUPERFAMILY SSF55729 1 147 2.29E-28 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase STK_01130 a3e66053ff731e0d3a1d78d02dc91c7e 153 Pfam PF00583 Acetyltransferase (GNAT) family 38 141 8.3E-18 T 23-10-2018 IPR000182 GNAT domain STK_01130 a3e66053ff731e0d3a1d78d02dc91c7e 153 Gene3D G3DSA:3.40.630.30 1 149 3.6E-27 T 23-10-2018 STK_20010 081e416eb85437156c605937296ec477 415 Pfam PF13635 Domain of unknown function (DUF4143) 263 362 1.6E-6 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 STK_20010 081e416eb85437156c605937296ec477 415 Pfam PF13173 AAA domain 33 162 7.7E-31 T 23-10-2018 STK_20010 081e416eb85437156c605937296ec477 415 SUPERFAMILY SSF52540 31 199 1.72E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_25510 839ca045a154f4d72af3a23bc72291be 473 Pfam PF13520 Amino acid permease 26 440 4.4E-29 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_25510 839ca045a154f4d72af3a23bc72291be 473 Gene3D G3DSA:1.20.1740.10 13 467 1.8E-31 T 23-10-2018 STK_25510 839ca045a154f4d72af3a23bc72291be 473 PIRSF PIRSF006060 1 471 7.7E-57 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_20157 5df7a0c2058f96a69c38511d47b46647 64 Pfam PF05942 Archaeal PaREP1/PaREP8 family 8 61 1.3E-12 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_20157 5df7a0c2058f96a69c38511d47b46647 64 Gene3D G3DSA:1.20.120.330 5 63 2.5E-19 T 23-10-2018 STK_10080 7d11408e6579245fdd1386dc6113a0b6 951 SUPERFAMILY SSF88688 463 566 4.9E-24 T 23-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily STK_10080 7d11408e6579245fdd1386dc6113a0b6 951 Gene3D G3DSA:3.20.110.10 206 413 4.1E-50 T 23-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily STK_10080 7d11408e6579245fdd1386dc6113a0b6 951 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 563 945 5.1E-75 T 23-10-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 STK_10080 7d11408e6579245fdd1386dc6113a0b6 951 SUPERFAMILY SSF74650 555 949 1.41E-80 T 23-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 STK_10080 7d11408e6579245fdd1386dc6113a0b6 951 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 212 448 6.1E-63 T 23-10-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 STK_10080 7d11408e6579245fdd1386dc6113a0b6 951 Gene3D G3DSA:1.20.1270.50 467 558 1.4E-22 T 23-10-2018 IPR037094 Glycoside hydrolase family 38, central domain superfamily GO:0004559|GO:0006013 STK_10080 7d11408e6579245fdd1386dc6113a0b6 951 Pfam PF09261 Alpha mannosidase middle domain 464 536 9.2E-23 T 23-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 STK_10080 7d11408e6579245fdd1386dc6113a0b6 951 Gene3D G3DSA:2.70.98.30 607 849 6.9E-15 T 23-10-2018 STK_10080 7d11408e6579245fdd1386dc6113a0b6 951 SMART SM00872 464 537 1.8E-29 T 23-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 STK_10080 7d11408e6579245fdd1386dc6113a0b6 951 SUPERFAMILY SSF88713 155 411 1.69E-60 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 STK_23530 81257dd7302fbf17868af64d3c0723a9 386 Gene3D G3DSA:3.90.25.10 211 370 4.5E-162 T 23-10-2018 STK_23530 81257dd7302fbf17868af64d3c0723a9 386 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 286 1.1E-24 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 STK_23530 81257dd7302fbf17868af64d3c0723a9 386 SUPERFAMILY SSF51735 2 370 1.66E-54 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_23530 81257dd7302fbf17868af64d3c0723a9 386 Gene3D G3DSA:3.40.50.720 3 294 4.5E-162 T 23-10-2018 STK_03230 e29283a6f2f54a24ddbd5c9ef5f2209a 426 SUPERFAMILY SSF52954 335 426 2.87E-19 T 23-10-2018 STK_03230 e29283a6f2f54a24ddbd5c9ef5f2209a 426 PIRSF PIRSF001549 1 426 1.2E-119 T 23-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 STK_03230 e29283a6f2f54a24ddbd5c9ef5f2209a 426 SUPERFAMILY SSF55681 4 330 2.79E-81 T 23-10-2018 STK_03230 e29283a6f2f54a24ddbd5c9ef5f2209a 426 Pfam PF03129 Anticodon binding domain 336 424 4.1E-13 T 23-10-2018 IPR004154 Anticodon-binding STK_03230 e29283a6f2f54a24ddbd5c9ef5f2209a 426 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 414 8.0E-113 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 STK_03230 e29283a6f2f54a24ddbd5c9ef5f2209a 426 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 424 28.233 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 STK_03230 e29283a6f2f54a24ddbd5c9ef5f2209a 426 Pfam PF13393 Histidyl-tRNA synthetase 9 318 3.7E-66 T 23-10-2018 STK_03230 e29283a6f2f54a24ddbd5c9ef5f2209a 426 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 16 375 22.876 T 23-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 STK_03230 e29283a6f2f54a24ddbd5c9ef5f2209a 426 Gene3D G3DSA:3.40.50.800 333 425 1.9E-16 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily STK_03230 e29283a6f2f54a24ddbd5c9ef5f2209a 426 Gene3D G3DSA:3.30.930.10 3 332 2.1E-92 T 23-10-2018 STK_16530 ea38b74228625231302aca1dd391e1d9 123 SUPERFAMILY SSF49764 18 114 6.63E-19 T 23-10-2018 IPR008978 HSP20-like chaperone STK_16530 ea38b74228625231302aca1dd391e1d9 123 Pfam PF00011 Hsp20/alpha crystallin family 32 114 5.8E-10 T 23-10-2018 IPR002068 Alpha crystallin/Hsp20 domain STK_16530 ea38b74228625231302aca1dd391e1d9 123 Gene3D G3DSA:2.60.40.790 1 123 2.9E-32 T 23-10-2018 IPR008978 HSP20-like chaperone STK_02506 236eafcf7e6b981c39a04b26dabc69b4 97 Pfam PF09339 IclR helix-turn-helix domain 13 58 6.5E-5 T 23-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 STK_02506 236eafcf7e6b981c39a04b26dabc69b4 97 SUPERFAMILY SSF46785 5 87 7.37E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_02506 236eafcf7e6b981c39a04b26dabc69b4 97 Gene3D G3DSA:1.10.10.10 3 93 6.7E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_09200 b260c2ffe6c750738226211cdf07de5c 298 Gene3D G3DSA:2.40.10.120 2 199 1.7E-51 T 23-10-2018 STK_09200 b260c2ffe6c750738226211cdf07de5c 298 PRINTS PR00834 HtrA/DegQ protease family signature 244 256 1.3E-33 T 23-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 STK_09200 b260c2ffe6c750738226211cdf07de5c 298 PRINTS PR00834 HtrA/DegQ protease family signature 160 177 1.3E-33 T 23-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 STK_09200 b260c2ffe6c750738226211cdf07de5c 298 PRINTS PR00834 HtrA/DegQ protease family signature 66 86 1.3E-33 T 23-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 STK_09200 b260c2ffe6c750738226211cdf07de5c 298 PRINTS PR00834 HtrA/DegQ protease family signature 45 57 1.3E-33 T 23-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 STK_09200 b260c2ffe6c750738226211cdf07de5c 298 PRINTS PR00834 HtrA/DegQ protease family signature 138 155 1.3E-33 T 23-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 STK_09200 b260c2ffe6c750738226211cdf07de5c 298 PRINTS PR00834 HtrA/DegQ protease family signature 103 127 1.3E-33 T 23-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 STK_09200 b260c2ffe6c750738226211cdf07de5c 298 Gene3D G3DSA:2.30.42.10 200 297 5.5E-24 T 23-10-2018 STK_09200 b260c2ffe6c750738226211cdf07de5c 298 SMART SM00228 204 285 1.5E-14 T 23-10-2018 IPR001478 PDZ domain GO:0005515 STK_09200 b260c2ffe6c750738226211cdf07de5c 298 SUPERFAMILY SSF50494 2 197 7.97E-47 T 23-10-2018 IPR009003 Peptidase S1, PA clan STK_09200 b260c2ffe6c750738226211cdf07de5c 298 Pfam PF13180 PDZ domain 204 292 1.7E-13 T 23-10-2018 IPR001478 PDZ domain GO:0005515 STK_09200 b260c2ffe6c750738226211cdf07de5c 298 Pfam PF13365 Trypsin-like peptidase domain 37 167 8.0E-23 T 23-10-2018 STK_09200 b260c2ffe6c750738226211cdf07de5c 298 SUPERFAMILY SSF50156 203 293 1.58E-18 T 23-10-2018 IPR036034 PDZ superfamily GO:0005515 STK_08440 1f5f664ff09932bc1a8558305b0c17bf 302 Pfam PF00924 Mechanosensitive ion channel 78 288 1.6E-24 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 STK_08440 1f5f664ff09932bc1a8558305b0c17bf 302 SUPERFAMILY SSF82861 36 118 9.15E-5 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 STK_08440 1f5f664ff09932bc1a8558305b0c17bf 302 SUPERFAMILY SSF50182 121 204 6.21E-11 T 23-10-2018 IPR010920 LSM domain superfamily STK_08440 1f5f664ff09932bc1a8558305b0c17bf 302 Gene3D G3DSA:2.30.30.60 165 206 1.2E-5 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily STK_05680 f0441fbadda25fc2bddb8b78c51f3ce3 429 Gene3D G3DSA:3.10.20.70 3 107 3.6E-9 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 STK_05680 f0441fbadda25fc2bddb8b78c51f3ce3 429 Pfam PF00120 Glutamine synthetase, catalytic domain 108 424 3.6E-74 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 STK_05680 f0441fbadda25fc2bddb8b78c51f3ce3 429 SMART SM01230 107 353 1.2E-67 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 STK_05680 f0441fbadda25fc2bddb8b78c51f3ce3 429 SUPERFAMILY SSF54368 7 106 2.09E-13 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 STK_05680 f0441fbadda25fc2bddb8b78c51f3ce3 429 SUPERFAMILY SSF55931 107 425 3.43E-76 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 STK_05680 f0441fbadda25fc2bddb8b78c51f3ce3 429 Gene3D G3DSA:3.30.590.10 110 427 2.3E-82 T 23-10-2018 STK_06270 bd36429c51bf01e3636aa9af174d5eb3 422 Gene3D G3DSA:3.30.70.360 178 334 1.1E-133 T 23-10-2018 STK_06270 bd36429c51bf01e3636aa9af174d5eb3 422 SUPERFAMILY SSF53187 2 419 1.11E-50 T 23-10-2018 STK_06270 bd36429c51bf01e3636aa9af174d5eb3 422 Pfam PF07687 Peptidase dimerisation domain 176 322 1.0E-13 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain STK_06270 bd36429c51bf01e3636aa9af174d5eb3 422 Gene3D G3DSA:3.40.630.10 10 410 1.1E-133 T 23-10-2018 STK_06270 bd36429c51bf01e3636aa9af174d5eb3 422 Pfam PF01546 Peptidase family M20/M25/M40 65 420 9.2E-38 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 STK_06940 ad4fb5badfc642d3f7ebdd18e9ca9f61 297 SUPERFAMILY SSF51735 83 259 4.34E-35 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_06940 ad4fb5badfc642d3f7ebdd18e9ca9f61 297 Gene3D G3DSA:3.40.50.720 23 284 9.9E-71 T 23-10-2018 STK_06940 ad4fb5badfc642d3f7ebdd18e9ca9f61 297 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 104 258 2.4E-34 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 STK_06940 ad4fb5badfc642d3f7ebdd18e9ca9f61 297 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 24 291 6.6E-14 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 STK_06940 ad4fb5badfc642d3f7ebdd18e9ca9f61 297 Gene3D G3DSA:3.40.50.720 83 259 9.9E-71 T 23-10-2018 STK_06940 ad4fb5badfc642d3f7ebdd18e9ca9f61 297 SUPERFAMILY SSF52283 2 98 2.13E-23 T 23-10-2018 STK_09480 eb836e9ee9644a6ef40eca4cacd628c0 293 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 4 287 1.8E-100 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 STK_09480 eb836e9ee9644a6ef40eca4cacd628c0 293 SUPERFAMILY SSF56281 4 283 1.57E-64 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_09480 eb836e9ee9644a6ef40eca4cacd628c0 293 Pfam PF00753 Metallo-beta-lactamase superfamily 21 105 4.1E-8 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_09480 eb836e9ee9644a6ef40eca4cacd628c0 293 Pfam PF12706 Beta-lactamase superfamily domain 186 257 8.6E-10 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_09480 eb836e9ee9644a6ef40eca4cacd628c0 293 Gene3D G3DSA:3.60.15.10 2 288 4.0E-72 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_09480 eb836e9ee9644a6ef40eca4cacd628c0 293 Hamap MF_01818 Ribonuclease BN [rbn]. 2 289 33.968 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 STK_25390 f9d703fd82675b7e690ed5647045cd86 693 SUPERFAMILY SSF53850 94 682 1.99E-81 T 23-10-2018 STK_25390 f9d703fd82675b7e690ed5647045cd86 693 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 257 602 2.0E-65 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain STK_25390 f9d703fd82675b7e690ed5647045cd86 693 Gene3D G3DSA:3.10.105.10 416 653 1.0E-31 T 23-10-2018 STK_25390 f9d703fd82675b7e690ed5647045cd86 693 PIRSF PIRSF002741 48 687 1.6E-43 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 STK_08200 94adac9d2119c21fca05c1d7f47147bd 545 Gene3D G3DSA:3.30.260.10 140 400 1.2E-181 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily STK_08200 94adac9d2119c21fca05c1d7f47147bd 545 SUPERFAMILY SSF48592 10 521 1.3E-83 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily STK_08200 94adac9d2119c21fca05c1d7f47147bd 545 SUPERFAMILY SSF54849 139 397 1.65E-23 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily STK_08200 94adac9d2119c21fca05c1d7f47147bd 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 52 70 8.2E-31 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_08200 94adac9d2119c21fca05c1d7f47147bd 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 368 390 8.2E-31 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_08200 94adac9d2119c21fca05c1d7f47147bd 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 402 414 8.2E-31 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_08200 94adac9d2119c21fca05c1d7f47147bd 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 82 101 8.2E-31 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_08200 94adac9d2119c21fca05c1d7f47147bd 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 30 46 8.2E-31 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_08200 94adac9d2119c21fca05c1d7f47147bd 545 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 4 520 6.5E-211 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 STK_08200 94adac9d2119c21fca05c1d7f47147bd 545 Gene3D G3DSA:1.10.560.10 21 518 1.2E-181 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily STK_08200 94adac9d2119c21fca05c1d7f47147bd 545 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 54 70 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_08200 94adac9d2119c21fca05c1d7f47147bd 545 Gene3D G3DSA:3.50.7.10 213 364 1.2E-181 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily STK_08200 94adac9d2119c21fca05c1d7f47147bd 545 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 82 90 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_08200 94adac9d2119c21fca05c1d7f47147bd 545 SUPERFAMILY SSF52029 207 373 3.4E-50 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily STK_08200 94adac9d2119c21fca05c1d7f47147bd 545 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 33 45 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_08200 94adac9d2119c21fca05c1d7f47147bd 545 Pfam PF00118 TCP-1/cpn60 chaperonin family 28 521 2.1E-160 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 STK_09410 7b591822042fd8885bff6dd3e82a386e 263 Gene3D G3DSA:2.40.50.140 1 84 1.9E-28 T 23-10-2018 STK_09410 7b591822042fd8885bff6dd3e82a386e 263 SMART SM00316 10 83 8.4E-17 T 23-10-2018 IPR022967 RNA-binding domain, S1 STK_09410 7b591822042fd8885bff6dd3e82a386e 263 SUPERFAMILY SSF110993 177 260 3.79E-21 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 STK_09410 7b591822042fd8885bff6dd3e82a386e 263 Pfam PF00575 S1 RNA binding domain 9 83 8.5E-13 T 23-10-2018 IPR003029 S1 domain GO:0003676 STK_09410 7b591822042fd8885bff6dd3e82a386e 263 Pfam PF07541 Eukaryotic translation initiation factor 2 alpha subunit 122 231 1.6E-24 T 23-10-2018 IPR011488 Translation initiation factor 2, alpha subunit GO:0003723|GO:0003743 Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 STK_09410 7b591822042fd8885bff6dd3e82a386e 263 SUPERFAMILY SSF50249 9 89 1.99E-19 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_09410 7b591822042fd8885bff6dd3e82a386e 263 Hamap MF_00231 Translation initiation factor 2 subunit alpha [eif2a]. 3 263 31.223 T 23-10-2018 IPR022964 Translation initiation factor 2, alpha subunit, archaeal STK_09410 7b591822042fd8885bff6dd3e82a386e 263 Gene3D G3DSA:3.30.70.1130 175 263 4.4E-21 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 STK_09410 7b591822042fd8885bff6dd3e82a386e 263 SUPERFAMILY SSF116742 85 173 9.68E-27 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 STK_09410 7b591822042fd8885bff6dd3e82a386e 263 Gene3D G3DSA:1.10.150.190 85 174 4.2E-28 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 STK_12800 6b162b0b52a313f419dc3e9a8691f87d 136 Pfam PF01982 Domain of unknown function DUF120 12 134 5.2E-40 T 23-10-2018 IPR023602 Riboflavin kinase domain, CTP-dependent GO:0016773 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 STK_12800 6b162b0b52a313f419dc3e9a8691f87d 136 SUPERFAMILY SSF82114 6 135 6.21E-41 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 STK_12800 6b162b0b52a313f419dc3e9a8691f87d 136 Gene3D G3DSA:2.40.30.30 3 136 1.6E-42 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 STK_12800 6b162b0b52a313f419dc3e9a8691f87d 136 Hamap MF_01285 Riboflavin kinase [ribK]. 6 134 28.594 T 23-10-2018 IPR023470 Riboflavin kinase, archaeal GO:0008531|GO:0009231 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 STK_08740 363195feeeff5969cf700d171a25180a 206 SMART SM00849 10 195 1.2E-25 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_08740 363195feeeff5969cf700d171a25180a 206 Gene3D G3DSA:3.60.15.10 2 205 1.2E-43 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_08740 363195feeeff5969cf700d171a25180a 206 Pfam PF00753 Metallo-beta-lactamase superfamily 10 195 4.8E-23 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_08740 363195feeeff5969cf700d171a25180a 206 SUPERFAMILY SSF56281 12 201 2.88E-40 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_16700 665845fafefa0daae717f39acce99670 468 Gene3D G3DSA:1.20.1250.20 3 181 6.1E-38 T 23-10-2018 STK_16700 665845fafefa0daae717f39acce99670 468 Gene3D G3DSA:1.20.1250.20 246 465 7.7E-19 T 23-10-2018 STK_16700 665845fafefa0daae717f39acce99670 468 Pfam PF07690 Major Facilitator Superfamily 11 400 2.9E-54 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_16700 665845fafefa0daae717f39acce99670 468 SUPERFAMILY SSF103473 4 461 3.4E-64 T 23-10-2018 IPR036259 MFS transporter superfamily STK_11460 2472abbc5faafa58c80fdd9433f8c262 152 SUPERFAMILY SSF140931 27 106 2.35E-6 T 23-10-2018 IPR036597 Fido-like domain superfamily STK_11460 2472abbc5faafa58c80fdd9433f8c262 152 Pfam PF02661 Fic/DOC family 57 103 9.9E-8 T 23-10-2018 IPR003812 Fido domain STK_11460 2472abbc5faafa58c80fdd9433f8c262 152 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 25 144 5.9E-41 T 23-10-2018 IPR006440 Death on curing protein GO:0016301 STK_11460 2472abbc5faafa58c80fdd9433f8c262 152 Gene3D G3DSA:1.20.120.1870 26 151 1.3E-10 T 23-10-2018 STK_20450 dbc7bf3278dccbcb2d542e0077ffbc01 388 SMART SM00852 176 311 1.2E-22 T 23-10-2018 IPR001453 MoaB/Mog domain STK_20450 dbc7bf3278dccbcb2d542e0077ffbc01 388 SUPERFAMILY SSF63882 3 170 1.57E-39 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 STK_20450 dbc7bf3278dccbcb2d542e0077ffbc01 388 Gene3D G3DSA:2.40.340.10 319 378 1.3E-71 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 STK_20450 dbc7bf3278dccbcb2d542e0077ffbc01 388 Pfam PF03453 MoeA N-terminal region (domain I and II) 3 164 8.8E-33 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 STK_20450 dbc7bf3278dccbcb2d542e0077ffbc01 388 SUPERFAMILY SSF53218 175 314 2.22E-26 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily STK_20450 dbc7bf3278dccbcb2d542e0077ffbc01 388 Gene3D G3DSA:3.90.105.10 28 171 1.3E-71 T 23-10-2018 STK_20450 dbc7bf3278dccbcb2d542e0077ffbc01 388 Gene3D G3DSA:2.170.190.11 47 138 1.3E-71 T 23-10-2018 STK_20450 dbc7bf3278dccbcb2d542e0077ffbc01 388 Gene3D G3DSA:3.40.980.10 172 318 1.3E-71 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily STK_20450 dbc7bf3278dccbcb2d542e0077ffbc01 388 Pfam PF00994 Probable molybdopterin binding domain 177 304 3.3E-16 T 23-10-2018 IPR001453 MoaB/Mog domain STK_07800 9403eacb136cfe1a101bb912a7dcaf3b 371 Gene3D G3DSA:1.20.1250.20 3 185 7.4E-14 T 23-10-2018 STK_07800 9403eacb136cfe1a101bb912a7dcaf3b 371 Gene3D G3DSA:1.20.1250.20 191 370 1.0E-10 T 23-10-2018 STK_07800 9403eacb136cfe1a101bb912a7dcaf3b 371 Pfam PF07690 Major Facilitator Superfamily 13 303 2.9E-15 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_07800 9403eacb136cfe1a101bb912a7dcaf3b 371 SUPERFAMILY SSF103473 4 368 9.68E-32 T 23-10-2018 IPR036259 MFS transporter superfamily STK_19610 e031ca40b464d3f03592167290bed73c 347 Gene3D G3DSA:3.90.550.10 1 257 4.2E-20 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_19610 e031ca40b464d3f03592167290bed73c 347 SUPERFAMILY SSF53448 3 222 4.45E-29 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_19610 e031ca40b464d3f03592167290bed73c 347 Pfam PF00535 Glycosyl transferase family 2 6 123 3.7E-11 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 STK_00040 d4615b6cdb2caa5429a3103657655abd 99 Gene3D G3DSA:3.30.160.60 1 54 1.4E-5 T 23-10-2018 STK_00040 d4615b6cdb2caa5429a3103657655abd 99 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 5 26 - T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 STK_10980 9fc624874160172c913802b9bdad5443 347 Pfam PF01385 Probable transposase 82 197 1.7E-36 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 STK_10980 9fc624874160172c913802b9bdad5443 347 Gene3D G3DSA:3.30.420.140 147 258 9.2E-6 T 23-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 STK_10980 9fc624874160172c913802b9bdad5443 347 Pfam PF07282 Putative transposase DNA-binding domain 212 280 2.0E-19 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_10980 9fc624874160172c913802b9bdad5443 347 SUPERFAMILY SSF53098 169 243 1.9E-5 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily STK_08330 748435da1eda67f3929efafa7612c720 855 Gene3D G3DSA:3.30.499.20 5 360 3.1E-148 T 23-10-2018 STK_08330 748435da1eda67f3929efafa7612c720 855 Pfam PF00694 Aconitase C-terminal domain 665 782 1.5E-36 T 23-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 STK_08330 748435da1eda67f3929efafa7612c720 855 SUPERFAMILY SSF53732 13 597 3.4E-206 T 23-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 STK_08330 748435da1eda67f3929efafa7612c720 855 Pfam PF00330 Aconitase family (aconitate hydratase) 71 532 1.8E-166 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 STK_08330 748435da1eda67f3929efafa7612c720 855 ProSitePatterns PS01244 Aconitase family signature 2. 463 476 - T 23-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 STK_08330 748435da1eda67f3929efafa7612c720 855 Gene3D G3DSA:3.30.499.10 361 560 7.4E-84 T 23-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 STK_08330 748435da1eda67f3929efafa7612c720 855 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 16 852 0.0 T 23-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 STK_08330 748435da1eda67f3929efafa7612c720 855 Gene3D G3DSA:1.10.1440.20 562 619 2.5E-17 T 23-10-2018 STK_08330 748435da1eda67f3929efafa7612c720 855 PRINTS PR00415 Aconitase family signature 401 412 1.9E-41 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 STK_08330 748435da1eda67f3929efafa7612c720 855 PRINTS PR00415 Aconitase family signature 360 374 1.9E-41 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 STK_08330 748435da1eda67f3929efafa7612c720 855 PRINTS PR00415 Aconitase family signature 196 209 1.9E-41 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 STK_08330 748435da1eda67f3929efafa7612c720 855 PRINTS PR00415 Aconitase family signature 210 225 1.9E-41 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 STK_08330 748435da1eda67f3929efafa7612c720 855 PRINTS PR00415 Aconitase family signature 163 171 1.9E-41 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 STK_08330 748435da1eda67f3929efafa7612c720 855 PRINTS PR00415 Aconitase family signature 286 299 1.9E-41 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 STK_08330 748435da1eda67f3929efafa7612c720 855 PRINTS PR00415 Aconitase family signature 463 476 1.9E-41 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 STK_08330 748435da1eda67f3929efafa7612c720 855 PRINTS PR00415 Aconitase family signature 139 152 1.9E-41 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 STK_08330 748435da1eda67f3929efafa7612c720 855 PRINTS PR00415 Aconitase family signature 272 285 1.9E-41 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 STK_08330 748435da1eda67f3929efafa7612c720 855 SUPERFAMILY SSF52016 601 852 6.08E-71 T 23-10-2018 STK_08330 748435da1eda67f3929efafa7612c720 855 Gene3D G3DSA:3.20.19.10 621 852 1.4E-92 T 23-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 STK_08330 748435da1eda67f3929efafa7612c720 855 ProSitePatterns PS00450 Aconitase family signature 1. 397 413 - T 23-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 STK_06190 55e2255768092b29d336c56ccdfd8c5c 291 PIRSF PIRSF000103 1 290 7.6E-69 T 23-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 STK_06190 55e2255768092b29d336c56ccdfd8c5c 291 SUPERFAMILY SSF51735 1 159 7.7E-35 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_06190 55e2255768092b29d336c56ccdfd8c5c 291 SUPERFAMILY SSF48179 160 284 2.04E-31 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 STK_06190 55e2255768092b29d336c56ccdfd8c5c 291 Gene3D G3DSA:3.40.50.720 1 158 7.8E-38 T 23-10-2018 STK_06190 55e2255768092b29d336c56ccdfd8c5c 291 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 158 2.2E-32 T 23-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 STK_06190 55e2255768092b29d336c56ccdfd8c5c 291 Gene3D G3DSA:1.10.1040.10 159 289 1.3E-31 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 STK_06190 55e2255768092b29d336c56ccdfd8c5c 291 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 161 282 5.9E-25 T 23-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 STK_14460 c7b3f7ae7d1089d1b73be8f74bcf1b61 131 Pfam PF13710 ACT domain 15 75 2.3E-6 T 23-10-2018 STK_06980 c209cb8d340443f73d7aa517e492f792 309 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 17 301 5.3E-68 T 23-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 STK_06980 c209cb8d340443f73d7aa517e492f792 309 Gene3D G3DSA:3.30.470.20 177 307 1.0E-29 T 23-10-2018 STK_06980 c209cb8d340443f73d7aa517e492f792 309 Gene3D G3DSA:3.30.1490.20 1 176 7.9E-37 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 STK_06980 c209cb8d340443f73d7aa517e492f792 309 SUPERFAMILY SSF56059 1 305 3.3E-65 T 23-10-2018 STK_13083 c1bceb3413ac45b48df70fb4a5f0925e 95 SUPERFAMILY SSF46785 14 89 1.96E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_13083 c1bceb3413ac45b48df70fb4a5f0925e 95 Gene3D G3DSA:1.10.10.10 10 95 4.4E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_14300 8c1ff770230d1f14948ecd2f5f6375b3 194 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 71 93 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 STK_14300 8c1ff770230d1f14948ecd2f5f6375b3 194 Gene3D G3DSA:1.20.120.1760 9 193 5.6E-43 T 23-10-2018 STK_14300 8c1ff770230d1f14948ecd2f5f6375b3 194 Pfam PF01066 CDP-alcohol phosphatidyltransferase 29 93 5.4E-11 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 STK_25240 5d953c497380b13380fec1e34e7eb3a6 473 Pfam PF00482 Type II secretion system (T2SS), protein F 19 142 2.3E-7 T 23-10-2018 IPR018076 Type II secretion system F domain STK_07430 30ebfbe4caad45cc4955ff87e5ddd0a7 125 Gene3D G3DSA:3.30.300.130 1 102 1.0E-29 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily STK_07430 30ebfbe4caad45cc4955ff87e5ddd0a7 125 Pfam PF01883 Iron-sulfur cluster assembly protein 9 79 5.9E-18 T 23-10-2018 IPR002744 MIP18 family-like STK_07430 30ebfbe4caad45cc4955ff87e5ddd0a7 125 SUPERFAMILY SSF117916 5 100 1.24E-25 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily STK_25320 893573368df9343e0c8f1b8b15ced52c 285 SUPERFAMILY SSF161098 85 255 1.96E-15 T 23-10-2018 IPR035906 MetI-like superfamily STK_25320 893573368df9343e0c8f1b8b15ced52c 285 Gene3D G3DSA:1.10.3720.10 68 284 4.3E-11 T 23-10-2018 IPR035906 MetI-like superfamily STK_25320 893573368df9343e0c8f1b8b15ced52c 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 284 5.5E-25 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 STK_09414 c259a16243801c74d3e0afa0d8bc9295 66 Pfam PF01667 Ribosomal protein S27 12 62 3.1E-22 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_09414 c259a16243801c74d3e0afa0d8bc9295 66 SUPERFAMILY SSF57829 12 64 7.14E-20 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 STK_09414 c259a16243801c74d3e0afa0d8bc9295 66 Gene3D G3DSA:2.20.25.640 1 63 3.4E-22 T 23-10-2018 STK_09414 c259a16243801c74d3e0afa0d8bc9295 66 ProSitePatterns PS01168 Ribosomal protein S27e signature. 20 52 - T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_09414 c259a16243801c74d3e0afa0d8bc9295 66 Hamap MF_00371 30S ribosomal protein S27e [rps27e]. 6 65 21.754 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_13830 1de019ef5ed8a14c0323755072675dca 313 Pfam PF04055 Radical SAM superfamily 15 169 1.6E-21 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_13830 1de019ef5ed8a14c0323755072675dca 313 TIGRFAM TIGR02668 moaA_archaeal: probable molybdenum cofactor biosynthesis protein A 1 304 8.3E-123 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 STK_13830 1de019ef5ed8a14c0323755072675dca 313 SMART SM00729 10 212 6.5E-7 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 STK_13830 1de019ef5ed8a14c0323755072675dca 313 SUPERFAMILY SSF102114 2 292 8.37E-69 T 23-10-2018 STK_13830 1de019ef5ed8a14c0323755072675dca 313 Pfam PF13353 4Fe-4S single cluster domain 16 102 8.2E-7 T 23-10-2018 STK_13830 1de019ef5ed8a14c0323755072675dca 313 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 16 27 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 STK_13830 1de019ef5ed8a14c0323755072675dca 313 Hamap MF_01225_A GTP 3',8-cyclase [moaA]. 1 304 45.57 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 STK_13830 1de019ef5ed8a14c0323755072675dca 313 Pfam PF06463 Molybdenum Cofactor Synthesis C 178 304 2.0E-27 T 23-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 STK_13830 1de019ef5ed8a14c0323755072675dca 313 Gene3D G3DSA:3.20.20.70 1 304 1.3E-77 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_04100 e6d5bfcd85eb86936d7e92dd2f863d10 194 Gene3D G3DSA:3.40.50.300 1 193 7.5E-60 T 23-10-2018 STK_04100 e6d5bfcd85eb86936d7e92dd2f863d10 194 SUPERFAMILY SSF52540 5 191 1.02E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_04100 e6d5bfcd85eb86936d7e92dd2f863d10 194 Pfam PF13207 AAA domain 7 149 5.5E-35 T 23-10-2018 STK_04100 e6d5bfcd85eb86936d7e92dd2f863d10 194 Hamap MF_00234 Adenylate kinase [adkA]. 2 194 48.208 T 23-10-2018 IPR023477 Adenylate kinase AdkA GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 STK_17880 4c1475591c1f9d12d5164e9351db6fb4 398 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 265 362 2.5E-21 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II STK_17880 4c1475591c1f9d12d5164e9351db6fb4 398 Gene3D G3DSA:3.40.50.970 4 248 6.5E-100 T 23-10-2018 STK_17880 4c1475591c1f9d12d5164e9351db6fb4 398 SUPERFAMILY SSF52518 5 247 2.14E-69 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold STK_17880 4c1475591c1f9d12d5164e9351db6fb4 398 Gene3D G3DSA:3.40.50.920 256 384 6.1E-29 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 STK_17880 4c1475591c1f9d12d5164e9351db6fb4 398 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 18 239 5.0E-70 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 STK_17880 4c1475591c1f9d12d5164e9351db6fb4 398 SUPERFAMILY SSF52922 256 380 2.71E-27 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 STK_20390 523fff9bfcef3a5b1bb18ee4b231c1f0 211 Gene3D G3DSA:1.10.10.10 3 73 8.9E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_20390 523fff9bfcef3a5b1bb18ee4b231c1f0 211 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 63 131 5.1E-27 T 23-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 STK_20390 523fff9bfcef3a5b1bb18ee4b231c1f0 211 SUPERFAMILY SSF47979 63 134 7.32E-24 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 STK_20390 523fff9bfcef3a5b1bb18ee4b231c1f0 211 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 58 8.1E-11 T 23-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 STK_20390 523fff9bfcef3a5b1bb18ee4b231c1f0 211 Pfam PF04023 FeoA domain 141 210 1.4E-5 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 STK_20390 523fff9bfcef3a5b1bb18ee4b231c1f0 211 SUPERFAMILY SSF46785 3 57 1.29E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_20390 523fff9bfcef3a5b1bb18ee4b231c1f0 211 SMART SM00529 25 123 1.4E-38 T 23-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 STK_20390 523fff9bfcef3a5b1bb18ee4b231c1f0 211 SMART SM00899 140 211 5.0E-8 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 STK_20390 523fff9bfcef3a5b1bb18ee4b231c1f0 211 Gene3D G3DSA:1.10.60.10 74 136 3.3E-23 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 STK_20390 523fff9bfcef3a5b1bb18ee4b231c1f0 211 SUPERFAMILY SSF50037 129 210 3.36E-5 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal STK_19220 2dde655af91f0cb95b03f5bb63b10857 561 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 358 505 1.8E-12 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_19220 2dde655af91f0cb95b03f5bb63b10857 561 Gene3D G3DSA:3.40.50.300 351 529 5.7E-9 T 23-10-2018 STK_19220 2dde655af91f0cb95b03f5bb63b10857 561 Pfam PF13175 AAA ATPase domain 266 326 1.1E-13 T 23-10-2018 STK_19220 2dde655af91f0cb95b03f5bb63b10857 561 SUPERFAMILY SSF52540 267 518 1.57E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_19220 2dde655af91f0cb95b03f5bb63b10857 561 Gene3D G3DSA:3.40.50.300 265 332 2.3E-11 T 23-10-2018 STK_21600 d03e7324767e5884172b6c78434cac9d 269 SUPERFAMILY SSF56317 3 262 5.1E-61 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily STK_21600 d03e7324767e5884172b6c78434cac9d 269 Gene3D G3DSA:3.60.110.10 1 254 1.6E-73 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily STK_21600 d03e7324767e5884172b6c78434cac9d 269 Pfam PF00795 Carbon-nitrogen hydrolase 7 248 1.7E-31 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 STK_12330 b4aac7b1cb24ea3cb0860c904a3c23c8 422 PIRSF PIRSF500824 1 422 7.3E-204 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 STK_12330 b4aac7b1cb24ea3cb0860c904a3c23c8 422 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 15 417 41.683 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 STK_12330 b4aac7b1cb24ea3cb0860c904a3c23c8 422 Gene3D G3DSA:3.40.50.1100 7 410 9.6E-171 T 23-10-2018 STK_12330 b4aac7b1cb24ea3cb0860c904a3c23c8 422 SUPERFAMILY SSF53686 21 413 3.54E-105 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme STK_12330 b4aac7b1cb24ea3cb0860c904a3c23c8 422 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 100 114 - T 23-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 STK_12330 b4aac7b1cb24ea3cb0860c904a3c23c8 422 Gene3D G3DSA:3.40.50.1100 8 232 9.6E-171 T 23-10-2018 STK_12330 b4aac7b1cb24ea3cb0860c904a3c23c8 422 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 72 404 4.3E-40 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme STK_12330 b4aac7b1cb24ea3cb0860c904a3c23c8 422 PIRSF PIRSF001413 3 422 2.8E-148 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 STK_12330 b4aac7b1cb24ea3cb0860c904a3c23c8 422 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 7 415 9.7E-193 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 STK_12430 f96e4c791120ed77a727307aab423717 220 SUPERFAMILY SSF89550 1 184 9.81E-41 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 STK_12430 f96e4c791120ed77a727307aab423717 220 SMART SM00481 4 63 2.3E-14 T 23-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal STK_12430 f96e4c791120ed77a727307aab423717 220 Pfam PF13263 PHP-associated 129 182 8.4E-14 T 23-10-2018 STK_12430 f96e4c791120ed77a727307aab423717 220 Gene3D G3DSA:3.20.20.140 1 189 2.2E-40 T 23-10-2018 STK_12430 f96e4c791120ed77a727307aab423717 220 Pfam PF02811 PHP domain 5 49 8.0E-6 T 23-10-2018 IPR004013 PHP domain GO:0003824 STK_17770 5688013dd1b84a6c29a1dee63dbb0ad7 102 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 2 45 2.5E-11 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_17770 5688013dd1b84a6c29a1dee63dbb0ad7 102 Pfam PF07282 Putative transposase DNA-binding domain 18 84 6.1E-22 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_04280 c4d9cbdcaec195dc707eaa1db50a3425 266 TIGRFAM TIGR03672 rpl4p_arch: 50S ribosomal protein uL4 9 258 4.3E-112 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 STK_04280 c4d9cbdcaec195dc707eaa1db50a3425 266 Hamap MF_01328_A 50S ribosomal protein L4 [rplD]. 9 259 42.79 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 STK_04280 c4d9cbdcaec195dc707eaa1db50a3425 266 ProSitePatterns PS00939 Ribosomal protein L1e signature. 112 138 - T 23-10-2018 IPR013000 Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04280 c4d9cbdcaec195dc707eaa1db50a3425 266 SUPERFAMILY SSF52166 10 258 9.94E-69 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 STK_04280 c4d9cbdcaec195dc707eaa1db50a3425 266 Pfam PF00573 Ribosomal protein L4/L1 family 23 258 8.4E-40 T 23-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 STK_04280 c4d9cbdcaec195dc707eaa1db50a3425 266 Gene3D G3DSA:3.40.1370.10 6 264 3.5E-87 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 STK_23410 19bb6e8e5617260931cddc8d87626dda 339 SUPERFAMILY SSF51735 135 306 7.1E-39 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_23410 19bb6e8e5617260931cddc8d87626dda 339 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 124 1.1E-25 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 STK_23410 19bb6e8e5617260931cddc8d87626dda 339 SUPERFAMILY SSF50129 3 337 2.99E-38 T 23-10-2018 IPR011032 GroES-like superfamily STK_23410 19bb6e8e5617260931cddc8d87626dda 339 Gene3D G3DSA:3.90.180.10 13 326 6.1E-92 T 23-10-2018 STK_23410 19bb6e8e5617260931cddc8d87626dda 339 Gene3D G3DSA:3.40.50.720 149 285 6.1E-92 T 23-10-2018 STK_23410 19bb6e8e5617260931cddc8d87626dda 339 SMART SM00829 9 337 7.1E-4 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 STK_23410 19bb6e8e5617260931cddc8d87626dda 339 Pfam PF00107 Zinc-binding dehydrogenase 171 300 1.0E-23 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 STK_24770 94a921529710f37b0e22ffbacfc31b7c 506 Pfam PF00171 Aldehyde dehydrogenase family 39 493 4.4E-112 T 23-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 STK_24770 94a921529710f37b0e22ffbacfc31b7c 506 Gene3D G3DSA:3.40.309.10 270 469 1.2E-129 T 23-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 STK_24770 94a921529710f37b0e22ffbacfc31b7c 506 SUPERFAMILY SSF53720 21 499 7.46E-123 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 STK_24770 94a921529710f37b0e22ffbacfc31b7c 506 Gene3D G3DSA:3.40.605.10 40 269 1.2E-129 T 23-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 STK_05690 d3b21fe4192ccf941e72f4e9599c924b 333 Gene3D G3DSA:3.90.180.10 13 323 8.4E-87 T 23-10-2018 STK_05690 d3b21fe4192ccf941e72f4e9599c924b 333 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 129 3.8E-31 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 STK_05690 d3b21fe4192ccf941e72f4e9599c924b 333 Gene3D G3DSA:3.40.50.720 147 281 8.4E-87 T 23-10-2018 STK_05690 d3b21fe4192ccf941e72f4e9599c924b 333 SUPERFAMILY SSF50129 2 162 2.13E-43 T 23-10-2018 IPR011032 GroES-like superfamily STK_05690 d3b21fe4192ccf941e72f4e9599c924b 333 Pfam PF00107 Zinc-binding dehydrogenase 171 294 2.2E-22 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 STK_05690 d3b21fe4192ccf941e72f4e9599c924b 333 SUPERFAMILY SSF51735 138 301 2.37E-34 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_05690 d3b21fe4192ccf941e72f4e9599c924b 333 SMART SM00829 10 330 0.0013 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 STK_21430 7c9228fc60684acc94e80938bc11c881 345 TIGRFAM TIGR00303 TIGR00303: TIGR00303 family protein 16 334 6.4E-109 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative STK_21430 7c9228fc60684acc94e80938bc11c881 345 Hamap MF_01086 UPF0284 protein . 1 345 129.033 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative STK_21430 7c9228fc60684acc94e80938bc11c881 345 SUPERFAMILY SSF52733 43 332 4.71E-46 T 23-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 STK_21430 7c9228fc60684acc94e80938bc11c881 345 Gene3D G3DSA:3.40.50.10210 13 343 1.5E-113 T 23-10-2018 STK_10810 e1b74cf6a3232533fbab862d295acfb6 204 Pfam PF07690 Major Facilitator Superfamily 13 145 6.6E-9 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_10810 e1b74cf6a3232533fbab862d295acfb6 204 SUPERFAMILY SSF103473 4 180 2.22E-16 T 23-10-2018 IPR036259 MFS transporter superfamily STK_10810 e1b74cf6a3232533fbab862d295acfb6 204 Gene3D G3DSA:1.20.1250.20 1 184 6.7E-14 T 23-10-2018 STK_18840 c14018635583ded18f8aa6d8b128013f 332 Gene3D G3DSA:3.40.800.20 3 330 9.1E-63 T 23-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 STK_18840 c14018635583ded18f8aa6d8b128013f 332 SUPERFAMILY SSF52768 2 301 5.28E-68 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily STK_18840 c14018635583ded18f8aa6d8b128013f 332 Pfam PF00850 Histone deacetylase domain 28 290 1.5E-51 T 23-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 STK_18840 c14018635583ded18f8aa6d8b128013f 332 PRINTS PR01270 Histone deacetylase superfamily signature 150 165 4.9E-14 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 STK_18840 c14018635583ded18f8aa6d8b128013f 332 PRINTS PR01270 Histone deacetylase superfamily signature 233 243 4.9E-14 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 STK_18840 c14018635583ded18f8aa6d8b128013f 332 PRINTS PR01270 Histone deacetylase superfamily signature 118 141 4.9E-14 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 STK_25260 6548aef4cba3cbfe0a796c5ff66c643a 646 SUPERFAMILY SSF48208 320 638 3.49E-27 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 STK_25260 6548aef4cba3cbfe0a796c5ff66c643a 646 Pfam PF04685 Glycosyl-hydrolase family 116, catalytic region 303 635 5.3E-73 T 23-10-2018 IPR006775 Glycosyl-hydrolase family 116, catalytic region GO:0004553 KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 STK_25260 6548aef4cba3cbfe0a796c5ff66c643a 646 Gene3D G3DSA:1.50.10.10 334 622 2.4E-15 T 23-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 STK_01930 430f82dee81f1cb89f654cc9e9d563b7 140 SMART SM00344 4 108 2.2E-25 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 STK_01930 430f82dee81f1cb89f654cc9e9d563b7 140 Pfam PF01037 Lrp/AsnC ligand binding domain 67 137 1.0E-12 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain STK_01930 430f82dee81f1cb89f654cc9e9d563b7 140 Gene3D G3DSA:3.30.70.920 56 139 7.7E-16 T 23-10-2018 STK_01930 430f82dee81f1cb89f654cc9e9d563b7 140 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 6.5E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_01930 430f82dee81f1cb89f654cc9e9d563b7 140 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 6.5E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_01930 430f82dee81f1cb89f654cc9e9d563b7 140 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 6.5E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_01930 430f82dee81f1cb89f654cc9e9d563b7 140 SUPERFAMILY SSF46785 4 56 2.81E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_01930 430f82dee81f1cb89f654cc9e9d563b7 140 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 51 6.8E-16 T 23-10-2018 STK_01930 430f82dee81f1cb89f654cc9e9d563b7 140 SUPERFAMILY SSF54909 63 138 2.15E-14 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel STK_01930 430f82dee81f1cb89f654cc9e9d563b7 140 Gene3D G3DSA:1.10.10.10 2 54 7.4E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_25230 20ed1c931e1c333a43a4b4a30fe0affe 513 Gene3D G3DSA:3.30.360.100 1 62 3.1E-39 T 23-10-2018 STK_25230 20ed1c931e1c333a43a4b4a30fe0affe 513 Pfam PF00437 Type II/IV secretion system protein 128 387 1.0E-46 T 23-10-2018 IPR001482 Type II/IV secretion system protein STK_25230 20ed1c931e1c333a43a4b4a30fe0affe 513 Gene3D G3DSA:1.10.8.1140 461 513 2.3E-27 T 23-10-2018 STK_25230 20ed1c931e1c333a43a4b4a30fe0affe 513 SUPERFAMILY SSF52540 114 493 2.16E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_25230 20ed1c931e1c333a43a4b4a30fe0affe 513 Gene3D G3DSA:3.30.450.90 127 224 3.8E-32 T 23-10-2018 STK_25230 20ed1c931e1c333a43a4b4a30fe0affe 513 Gene3D G3DSA:3.40.50.300 225 460 1.1E-94 T 23-10-2018 STK_25230 20ed1c931e1c333a43a4b4a30fe0affe 513 Gene3D G3DSA:1.10.390.40 63 126 4.5E-38 T 23-10-2018 STK_15070 c0dd32e90f0d2bbf28708217a1cdaddf 318 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 187 211 - T 23-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 STK_15070 c0dd32e90f0d2bbf28708217a1cdaddf 318 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 185 1.6E-48 T 23-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 STK_15070 c0dd32e90f0d2bbf28708217a1cdaddf 318 SUPERFAMILY SSF51735 1 187 1.13E-45 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_15070 c0dd32e90f0d2bbf28708217a1cdaddf 318 PIRSF PIRSF000105 1 317 2.1E-63 T 23-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 STK_15070 c0dd32e90f0d2bbf28708217a1cdaddf 318 Gene3D G3DSA:1.10.1040.10 192 317 8.8E-37 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 STK_15070 c0dd32e90f0d2bbf28708217a1cdaddf 318 SUPERFAMILY SSF48179 190 266 1.87E-14 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 STK_15070 c0dd32e90f0d2bbf28708217a1cdaddf 318 Gene3D G3DSA:3.40.50.720 1 191 4.4E-51 T 23-10-2018 STK_15070 c0dd32e90f0d2bbf28708217a1cdaddf 318 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 274 5.2E-19 T 23-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 STK_10880 7082298ce74aa8bade73b36608ae58bf 337 SUPERFAMILY SSF57997 26 216 4.97E-7 T 23-10-2018 STK_10880 7082298ce74aa8bade73b36608ae58bf 337 Gene3D G3DSA:1.25.40.10 10 244 4.8E-6 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 STK_08040 e68a5852cb22f4db9c1f9a59b354e27e 289 SUPERFAMILY SSF56176 4 158 4.49E-14 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 STK_08040 e68a5852cb22f4db9c1f9a59b354e27e 289 Gene3D G3DSA:3.30.465.40 5 166 3.5E-9 T 23-10-2018 STK_08040 e68a5852cb22f4db9c1f9a59b354e27e 289 Pfam PF01565 FAD binding domain 5 122 1.1E-9 T 23-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 STK_00360 05b58ccaf880ab9dbaddab37fc11c690 128 SUPERFAMILY SSF88723 2 125 2.38E-19 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_00360 05b58ccaf880ab9dbaddab37fc11c690 128 Gene3D G3DSA:3.40.50.1010 1 128 9.5E-20 T 23-10-2018 STK_00360 05b58ccaf880ab9dbaddab37fc11c690 128 Pfam PF01850 PIN domain 1 120 3.5E-16 T 23-10-2018 IPR002716 PIN domain STK_25115 f08f46dd0ca5d291e77bf6fa1ebe3699 68 Gene3D G3DSA:1.10.1220.10 20 64 1.5E-13 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 STK_25115 f08f46dd0ca5d291e77bf6fa1ebe3699 68 SUPERFAMILY SSF47598 20 62 6.67E-11 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 STK_25115 f08f46dd0ca5d291e77bf6fa1ebe3699 68 Pfam PF01402 Ribbon-helix-helix protein, copG family 22 59 4.5E-10 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 STK_03187 ddf072776746f5bb09cdf9831d54054e 82 Pfam PF09138 Urm1 (Ubiquitin related modifier) 31 82 1.2E-5 T 23-10-2018 IPR015221 Ubiquitin-related modifier 1 GO:0005737|GO:0034227 Reactome: R-HSA-6782315 STK_03187 ddf072776746f5bb09cdf9831d54054e 82 Gene3D G3DSA:3.10.20.30 1 82 1.1E-21 T 23-10-2018 IPR012675 Beta-grasp domain superfamily STK_03187 ddf072776746f5bb09cdf9831d54054e 82 SUPERFAMILY SSF54285 1 82 5.61E-12 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp STK_11600 9d4df58ac4f7b6155c25bc0546086ba6 434 Pfam PF01385 Probable transposase 170 284 4.6E-36 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 STK_11600 9d4df58ac4f7b6155c25bc0546086ba6 434 Pfam PF07282 Putative transposase DNA-binding domain 300 367 8.3E-19 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_02760 1079b3d48680678d8f457309c5e26583 880 Gene3D G3DSA:1.20.120.1280 1 121 9.8E-32 T 23-10-2018 STK_02760 1079b3d48680678d8f457309c5e26583 880 Gene3D G3DSA:1.20.120.1280 229 278 2.6E-11 T 23-10-2018 STK_02760 1079b3d48680678d8f457309c5e26583 880 Pfam PF00623 RNA polymerase Rpb1, domain 2 315 482 6.2E-76 T 23-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_02760 1079b3d48680678d8f457309c5e26583 880 Pfam PF05000 RNA polymerase Rpb1, domain 4 677 782 1.2E-31 T 23-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_02760 1079b3d48680678d8f457309c5e26583 880 TIGRFAM TIGR02390 RNA_pol_rpoA1: DNA-directed RNA polymerase subunit A' 4 872 0.0 T 23-10-2018 IPR012758 DNA-directed RNA polymerase subunit A' (Rpo1N) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_02760 1079b3d48680678d8f457309c5e26583 880 SMART SM00663 205 510 1.6E-209 T 23-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_02760 1079b3d48680678d8f457309c5e26583 880 Pfam PF04997 RNA polymerase Rpb1, domain 1 4 313 2.8E-102 T 23-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_02760 1079b3d48680678d8f457309c5e26583 880 SUPERFAMILY SSF64484 4 866 0.0 T 23-10-2018 STK_02760 1079b3d48680678d8f457309c5e26583 880 Pfam PF04983 RNA polymerase Rpb1, domain 3 485 651 3.4E-37 T 23-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_02760 1079b3d48680678d8f457309c5e26583 880 Gene3D G3DSA:2.60.40.2940 555 601 4.6E-26 T 23-10-2018 STK_02760 1079b3d48680678d8f457309c5e26583 880 Pfam PF04998 RNA polymerase Rpb1, domain 5 789 854 1.1E-24 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_02760 1079b3d48680678d8f457309c5e26583 880 Gene3D G3DSA:1.10.10.1950 483 526 3.8E-12 T 23-10-2018 STK_02760 1079b3d48680678d8f457309c5e26583 880 Gene3D G3DSA:1.10.10.1950 602 647 1.9E-17 T 23-10-2018 STK_02760 1079b3d48680678d8f457309c5e26583 880 Gene3D G3DSA:3.30.1490.180 348 413 3.9E-84 T 23-10-2018 STK_02760 1079b3d48680678d8f457309c5e26583 880 Gene3D G3DSA:2.20.25.410 828 880 4.5E-26 T 23-10-2018 STK_02760 1079b3d48680678d8f457309c5e26583 880 Gene3D G3DSA:1.10.132.30 648 791 3.5E-47 T 23-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_02760 1079b3d48680678d8f457309c5e26583 880 Gene3D G3DSA:2.40.40.20 305 477 3.9E-84 T 23-10-2018 STK_19440 2ed05fcb3747d4c83ee520e506b1c027 293 SUPERFAMILY SSF46955 12 61 2.44E-9 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily STK_19440 2ed05fcb3747d4c83ee520e506b1c027 293 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 12 60 4.1E-12 T 23-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 STK_19440 2ed05fcb3747d4c83ee520e506b1c027 293 Pfam PF12728 Helix-turn-helix domain 12 61 4.5E-14 T 23-10-2018 STK_19440 2ed05fcb3747d4c83ee520e506b1c027 293 Gene3D G3DSA:1.10.1660.10 10 61 2.1E-10 T 23-10-2018 STK_19440 2ed05fcb3747d4c83ee520e506b1c027 293 Pfam PF01435 Peptidase family M48 134 257 9.1E-8 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 STK_22560 a6bc9b22f66471478a586fd5fe31deea 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 103 3.5E-16 T 23-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 STK_22560 a6bc9b22f66471478a586fd5fe31deea 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 372 5.7E-43 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 STK_22560 a6bc9b22f66471478a586fd5fe31deea 379 Gene3D G3DSA:1.20.140.10 232 379 3.9E-44 T 23-10-2018 STK_22560 a6bc9b22f66471478a586fd5fe31deea 379 Gene3D G3DSA:1.10.540.10 1 116 5.7E-21 T 23-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 STK_22560 a6bc9b22f66471478a586fd5fe31deea 379 PIRSF PIRSF016578 4 374 6.0E-22 T 23-10-2018 STK_22560 a6bc9b22f66471478a586fd5fe31deea 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 23-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 STK_22560 a6bc9b22f66471478a586fd5fe31deea 379 SUPERFAMILY SSF47203 225 375 5.48E-45 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 STK_22560 a6bc9b22f66471478a586fd5fe31deea 379 SUPERFAMILY SSF56645 1 226 3.66E-55 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 STK_22560 a6bc9b22f66471478a586fd5fe31deea 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 215 4.5E-23 T 23-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 STK_22560 a6bc9b22f66471478a586fd5fe31deea 379 Gene3D G3DSA:2.40.110.10 119 231 1.0E-33 T 23-10-2018 STK_13727 c1dc06f894b9eabb6d413450d37b7b49 51 Hamap MF_00629 50S ribosomal protein L39e [rpl39e]. 1 51 17.84 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_13727 c1dc06f894b9eabb6d413450d37b7b49 51 Gene3D G3DSA:1.10.1620.10 1 51 1.1E-19 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily STK_13727 c1dc06f894b9eabb6d413450d37b7b49 51 ProSitePatterns PS00051 Ribosomal protein L39e signature. 30 46 - T 23-10-2018 IPR020083 Ribosomal protein L39e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_13727 c1dc06f894b9eabb6d413450d37b7b49 51 Pfam PF00832 Ribosomal L39 protein 9 50 7.6E-22 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_13727 c1dc06f894b9eabb6d413450d37b7b49 51 SUPERFAMILY SSF48662 4 51 6.28E-19 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily STK_06040 0d1a33b21737a21dccc3db2b13a0f5c9 147 Pfam PF01878 EVE domain 2 141 2.4E-17 T 23-10-2018 IPR002740 EVE domain STK_06040 0d1a33b21737a21dccc3db2b13a0f5c9 147 SUPERFAMILY SSF88697 2 142 1.82E-31 T 23-10-2018 IPR015947 PUA-like superfamily STK_06040 0d1a33b21737a21dccc3db2b13a0f5c9 147 Gene3D G3DSA:3.10.590.10 1 143 2.6E-29 T 23-10-2018 STK_23040 c1c4ac0c55401a27c7596d74b1894c51 375 Gene3D G3DSA:3.10.580.10 123 281 3.9E-33 T 23-10-2018 STK_23040 c1c4ac0c55401a27c7596d74b1894c51 375 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 278 363 6.0E-5 T 23-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 STK_23040 c1c4ac0c55401a27c7596d74b1894c51 375 SUPERFAMILY SSF54631 122 258 1.31E-30 T 23-10-2018 STK_23040 c1c4ac0c55401a27c7596d74b1894c51 375 SUPERFAMILY SSF69754 273 370 6.8E-11 T 23-10-2018 IPR036567 Ribosome hibernation promotion factor-like STK_23040 c1c4ac0c55401a27c7596d74b1894c51 375 Pfam PF00571 CBS domain 127 180 5.6E-13 T 23-10-2018 IPR000644 CBS domain STK_23040 c1c4ac0c55401a27c7596d74b1894c51 375 Pfam PF00571 CBS domain 10 55 4.4E-4 T 23-10-2018 IPR000644 CBS domain STK_23040 c1c4ac0c55401a27c7596d74b1894c51 375 Pfam PF00571 CBS domain 203 257 9.5E-7 T 23-10-2018 IPR000644 CBS domain STK_23040 c1c4ac0c55401a27c7596d74b1894c51 375 Pfam PF00571 CBS domain 82 116 0.0022 T 23-10-2018 IPR000644 CBS domain STK_23040 c1c4ac0c55401a27c7596d74b1894c51 375 Gene3D G3DSA:3.10.580.10 8 114 6.4E-15 T 23-10-2018 STK_23040 c1c4ac0c55401a27c7596d74b1894c51 375 SMART SM00116 10 57 4.8 T 23-10-2018 IPR000644 CBS domain STK_23040 c1c4ac0c55401a27c7596d74b1894c51 375 SMART SM00116 69 117 0.019 T 23-10-2018 IPR000644 CBS domain STK_23040 c1c4ac0c55401a27c7596d74b1894c51 375 SMART SM00116 210 257 0.022 T 23-10-2018 IPR000644 CBS domain STK_23040 c1c4ac0c55401a27c7596d74b1894c51 375 SMART SM00116 134 181 1.2E-9 T 23-10-2018 IPR000644 CBS domain STK_23040 c1c4ac0c55401a27c7596d74b1894c51 375 SUPERFAMILY SSF54631 11 117 4.67E-17 T 23-10-2018 STK_23040 c1c4ac0c55401a27c7596d74b1894c51 375 PIRSF PIRSF036983 1 375 4.3E-120 T 23-10-2018 IPR014651 Uncharacterised conserved protein, 2xCBS, MJ1404 type STK_12190 af1cb13a96c6c93a51e1a8c7998cb385 204 SMART SM00478 42 199 8.2E-4 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 STK_12190 af1cb13a96c6c93a51e1a8c7998cb385 204 Hamap MF_00241 Probable N-glycosylase/DNA lyase [ogg]. 1 204 31.943 T 23-10-2018 IPR012092 8-oxoguanine DNA glycosylase/DNA lyase, thermostable GO:0003906|GO:0006281|GO:0016799 STK_12190 af1cb13a96c6c93a51e1a8c7998cb385 204 Gene3D G3DSA:1.10.340.30 28 140 2.3E-55 T 23-10-2018 STK_12190 af1cb13a96c6c93a51e1a8c7998cb385 204 PIRSF PIRSF005954 1 204 2.1E-78 T 23-10-2018 IPR012092 8-oxoguanine DNA glycosylase/DNA lyase, thermostable GO:0003906|GO:0006281|GO:0016799 STK_12190 af1cb13a96c6c93a51e1a8c7998cb385 204 SUPERFAMILY SSF48150 9 199 2.79E-21 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 STK_12190 af1cb13a96c6c93a51e1a8c7998cb385 204 Gene3D G3DSA:1.10.1670.10 16 204 2.3E-55 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 STK_13560 578f1df105625ab12bd66d628a16e3f3 343 SMART SM00846 4 141 1.7E-11 T 23-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_13560 578f1df105625ab12bd66d628a16e3f3 343 SUPERFAMILY SSF51735 4 160 2.68E-47 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_13560 578f1df105625ab12bd66d628a16e3f3 343 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 148 298 3.4E-21 T 23-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_13560 578f1df105625ab12bd66d628a16e3f3 343 Hamap MF_00559 Glyceraldehyde-3-phosphate dehydrogenase [gap]. 1 343 181.294 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 STK_13560 578f1df105625ab12bd66d628a16e3f3 343 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 139 146 - T 23-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_13560 578f1df105625ab12bd66d628a16e3f3 343 TIGRFAM TIGR01546 GAPDH-II_archae: glyceraldehyde-3-phosphate dehydrogenase, type II 6 338 1.3E-157 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 STK_13560 578f1df105625ab12bd66d628a16e3f3 343 PIRSF PIRSF000149 2 322 5.2E-77 T 23-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_13560 578f1df105625ab12bd66d628a16e3f3 343 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 4 107 1.2E-10 T 23-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 STK_13560 578f1df105625ab12bd66d628a16e3f3 343 Gene3D G3DSA:3.40.50.720 6 330 1.4E-142 T 23-10-2018 STK_13560 578f1df105625ab12bd66d628a16e3f3 343 Gene3D G3DSA:3.30.360.10 139 336 1.4E-142 T 23-10-2018 STK_13560 578f1df105625ab12bd66d628a16e3f3 343 SUPERFAMILY SSF55347 141 303 2.7E-51 T 23-10-2018 STK_06690 415e60687a0b23ba4243d467be2a6117 226 Gene3D G3DSA:3.20.20.190 1 221 1.1E-66 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 STK_06690 415e60687a0b23ba4243d467be2a6117 226 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 6 214 5.8E-34 T 23-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 STK_06690 415e60687a0b23ba4243d467be2a6117 226 SUPERFAMILY SSF51695 1 219 4.97E-63 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 STK_00380 fb70415e807aaae9a8d250c74b60ddad 307 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 18 102 3.1E-22 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 STK_00380 fb70415e807aaae9a8d250c74b60ddad 307 Gene3D G3DSA:3.40.50.720 118 256 2.6E-95 T 23-10-2018 STK_00380 fb70415e807aaae9a8d250c74b60ddad 307 Gene3D G3DSA:3.90.180.10 17 299 2.6E-95 T 23-10-2018 STK_00380 fb70415e807aaae9a8d250c74b60ddad 307 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 29 43 - T 23-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 STK_00380 fb70415e807aaae9a8d250c74b60ddad 307 Pfam PF00107 Zinc-binding dehydrogenase 144 270 4.9E-25 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 STK_00380 fb70415e807aaae9a8d250c74b60ddad 307 SMART SM00829 2 305 8.9E-5 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 STK_00380 fb70415e807aaae9a8d250c74b60ddad 307 SUPERFAMILY SSF50129 20 141 6.6E-35 T 23-10-2018 IPR011032 GroES-like superfamily STK_00380 fb70415e807aaae9a8d250c74b60ddad 307 SUPERFAMILY SSF51735 106 276 1.24E-39 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_15700 4a28ab6121ca4a508758cbf03bc524d9 139 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 6 32 2.7E-5 T 23-10-2018 IPR007296 Domain of unknown function DUF403 STK_20690 1f0a392a3e29b0d28f3008339d041f52 177 TIGRFAM TIGR01018 uS4_arch: ribosomal protein uS4 1 162 1.3E-71 T 23-10-2018 IPR005710 Ribosomal protein S4/S9, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_20690 1f0a392a3e29b0d28f3008339d041f52 177 SUPERFAMILY SSF55174 10 163 1.7E-31 T 23-10-2018 STK_20690 1f0a392a3e29b0d28f3008339d041f52 177 SMART SM00363 104 172 4.9E-12 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_20690 1f0a392a3e29b0d28f3008339d041f52 177 Pfam PF01479 S4 domain 104 149 4.6E-16 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_20690 1f0a392a3e29b0d28f3008339d041f52 177 Hamap MF_01306_A 30S ribosomal protein S4 [rpsD]. 1 157 34.049 T 23-10-2018 IPR022802 Ribosomal protein S4, archaeal GO:0006412|GO:0019843 STK_20690 1f0a392a3e29b0d28f3008339d041f52 177 ProSitePatterns PS00632 Ribosomal protein S4 signature. 102 126 - T 23-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_20690 1f0a392a3e29b0d28f3008339d041f52 177 SMART SM01390 5 103 2.4E-21 T 23-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 STK_20690 1f0a392a3e29b0d28f3008339d041f52 177 Gene3D G3DSA:3.10.290.10 103 177 5.4E-17 T 23-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 STK_07940 b6d8eb75370f954af58d42363b6ac5be 141 SMART SM00748 10 134 1.0E-33 T 23-10-2018 IPR007842 HEPN domain STK_07940 b6d8eb75370f954af58d42363b6ac5be 141 Pfam PF05168 HEPN domain 7 133 5.4E-28 T 23-10-2018 IPR007842 HEPN domain STK_07940 b6d8eb75370f954af58d42363b6ac5be 141 SUPERFAMILY SSF81593 9 135 2.71E-26 T 23-10-2018 STK_07940 b6d8eb75370f954af58d42363b6ac5be 141 Gene3D G3DSA:1.20.120.330 5 140 1.2E-23 T 23-10-2018 STK_18250 02f7036e4e323e3ebef8de4c33b9ac24 222 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 5 214 9.5E-34 T 23-10-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 STK_18250 02f7036e4e323e3ebef8de4c33b9ac24 222 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 200 1.8E-27 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 STK_18250 02f7036e4e323e3ebef8de4c33b9ac24 222 SUPERFAMILY SSF53790 1 218 1.28E-36 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 STK_18250 02f7036e4e323e3ebef8de4c33b9ac24 222 Gene3D G3DSA:3.40.1010.10 1 110 5.3E-22 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 STK_05520 5f76463936d590fe9c662315003f42b7 562 SUPERFAMILY SSF51703 15 556 2.35E-215 T 23-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 STK_05520 5f76463936d590fe9c662315003f42b7 562 Gene3D G3DSA:3.20.20.240 1 562 3.0E-248 T 23-10-2018 STK_05520 5f76463936d590fe9c662315003f42b7 562 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 38 561 3.3E-240 T 23-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 STK_05520 5f76463936d590fe9c662315003f42b7 562 Pfam PF01642 Methylmalonyl-CoA mutase 40 554 7.2E-220 T 23-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 STK_02035 0d4f8801ad48d360690f76bac8618ecc 56 SUPERFAMILY SSF57829 1 55 1.14E-18 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 STK_02035 0d4f8801ad48d360690f76bac8618ecc 56 Hamap MF_00788 50S ribosomal protein L40e [rpl40e]. 7 52 16.659 T 23-10-2018 IPR023657 Ribosomal protein L40e, archaeal GO:0003735|GO:0005840|GO:0006412 STK_02035 0d4f8801ad48d360690f76bac8618ecc 56 Pfam PF01020 Ribosomal L40e family 10 49 1.1E-8 T 23-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 STK_02035 0d4f8801ad48d360690f76bac8618ecc 56 SMART SM01377 3 51 1.1E-19 T 23-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 STK_02035 0d4f8801ad48d360690f76bac8618ecc 56 Gene3D G3DSA:2.20.28.70 1 56 5.2E-29 T 23-10-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 STK_24430 60f2020f4232532dd9fb83c4dea66dc0 348 Pfam PF03824 High-affinity nickel-transport protein 41 332 7.2E-93 T 23-10-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 STK_24430 60f2020f4232532dd9fb83c4dea66dc0 348 TIGRFAM TIGR00802 nico: transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family 44 327 1.4E-105 T 23-10-2018 IPR004688 Transition metal uptake transporter nickel/cobalt GO:0015099|GO:0016021|GO:0035444|GO:0046872 STK_14250 279bf239a54bbe1082c73f5cc44f528d 414 Gene3D G3DSA:3.40.50.2000 1 235 3.5E-9 T 23-10-2018 STK_14250 279bf239a54bbe1082c73f5cc44f528d 414 Gene3D G3DSA:3.40.50.2000 236 409 4.2E-14 T 23-10-2018 STK_14250 279bf239a54bbe1082c73f5cc44f528d 414 Pfam PF00534 Glycosyl transferases group 1 226 375 5.9E-11 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 STK_14250 279bf239a54bbe1082c73f5cc44f528d 414 SUPERFAMILY SSF53756 9 408 5.23E-33 T 23-10-2018 STK_11710 4050abbb7598f567159de04e266e713e 102 SUPERFAMILY SSF50022 3 89 2.1E-16 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 STK_11710 4050abbb7598f567159de04e266e713e 102 Gene3D G3DSA:2.102.10.10 2 89 1.7E-13 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 STK_11710 4050abbb7598f567159de04e266e713e 102 Pfam PF00355 Rieske [2Fe-2S] domain 5 68 1.4E-8 T 23-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 STK_18170 be975f65c95c116d82a308153b9ee841 222 Gene3D G3DSA:3.30.950.10 124 221 4.8E-8 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 STK_18170 be975f65c95c116d82a308153b9ee841 222 Gene3D G3DSA:3.40.1010.10 1 122 8.7E-26 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 STK_18170 be975f65c95c116d82a308153b9ee841 222 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 3 215 4.1E-56 T 23-10-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 STK_18170 be975f65c95c116d82a308153b9ee841 222 PIRSF PIRSF036427 1 222 6.7E-63 T 23-10-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 STK_18170 be975f65c95c116d82a308153b9ee841 222 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 23-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 STK_18170 be975f65c95c116d82a308153b9ee841 222 SUPERFAMILY SSF53790 4 215 5.89E-34 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 STK_18170 be975f65c95c116d82a308153b9ee841 222 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 201 1.0E-34 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 STK_04970 5ae6ac3bb9c4314eeaeb2312319a519c 566 Pfam PF02910 Fumarate reductase flavoprotein C-term 442 566 1.0E-45 T 23-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 STK_04970 5ae6ac3bb9c4314eeaeb2312319a519c 566 Gene3D G3DSA:3.50.50.60 7 396 6.1E-148 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_04970 5ae6ac3bb9c4314eeaeb2312319a519c 566 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 41 50 - T 23-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 STK_04970 5ae6ac3bb9c4314eeaeb2312319a519c 566 PIRSF PIRSF000171 1 564 7.4E-54 T 23-10-2018 STK_04970 5ae6ac3bb9c4314eeaeb2312319a519c 566 Gene3D G3DSA:4.10.80.40 529 562 2.0E-5 T 23-10-2018 STK_04970 5ae6ac3bb9c4314eeaeb2312319a519c 566 SUPERFAMILY SSF56425 229 345 7.18E-40 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 STK_04970 5ae6ac3bb9c4314eeaeb2312319a519c 566 SUPERFAMILY SSF51905 2 409 3.42E-69 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_04970 5ae6ac3bb9c4314eeaeb2312319a519c 566 Pfam PF00890 FAD binding domain 7 386 6.5E-111 T 23-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 STK_04970 5ae6ac3bb9c4314eeaeb2312319a519c 566 SUPERFAMILY SSF46977 433 566 6.8E-54 T 23-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 STK_04970 5ae6ac3bb9c4314eeaeb2312319a519c 566 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 566 1.5E-250 T 23-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 STK_04970 5ae6ac3bb9c4314eeaeb2312319a519c 566 Gene3D G3DSA:3.90.700.10 239 340 6.1E-148 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 STK_04970 5ae6ac3bb9c4314eeaeb2312319a519c 566 Gene3D G3DSA:1.20.58.100 412 528 4.2E-37 T 23-10-2018 STK_08280 6de56c18a29ee2c3564a44b091dd536d 360 Gene3D G3DSA:3.40.50.410 40 202 3.0E-24 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily STK_08280 6de56c18a29ee2c3564a44b091dd536d 360 SMART SM00327 38 201 5.0E-12 T 23-10-2018 IPR002035 von Willebrand factor, type A STK_08280 6de56c18a29ee2c3564a44b091dd536d 360 SUPERFAMILY SSF53300 39 199 1.43E-21 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily STK_08280 6de56c18a29ee2c3564a44b091dd536d 360 Pfam PF00092 von Willebrand factor type A domain 42 199 4.6E-10 T 23-10-2018 IPR002035 von Willebrand factor, type A STK_17950 016b1425cb77a06d95eac66caf53aeb0 406 Gene3D G3DSA:3.30.9.10 72 364 6.4E-62 T 23-10-2018 STK_17950 016b1425cb77a06d95eac66caf53aeb0 406 SUPERFAMILY SSF54373 174 262 2.24E-6 T 23-10-2018 STK_17950 016b1425cb77a06d95eac66caf53aeb0 406 SUPERFAMILY SSF51905 4 341 3.52E-34 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_17950 016b1425cb77a06d95eac66caf53aeb0 406 Pfam PF12831 FAD dependent oxidoreductase 6 158 7.1E-12 T 23-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal STK_17950 016b1425cb77a06d95eac66caf53aeb0 406 Gene3D G3DSA:3.50.50.60 6 348 6.4E-62 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_17950 016b1425cb77a06d95eac66caf53aeb0 406 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 5.7E-5 T 23-10-2018 STK_17950 016b1425cb77a06d95eac66caf53aeb0 406 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 5.7E-5 T 23-10-2018 STK_05900 60987104f9df9ed3ade0ddff0d0f0216 704 SUPERFAMILY SSF52540 37 402 3.34E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_05900 60987104f9df9ed3ade0ddff0d0f0216 704 Gene3D G3DSA:3.40.50.300 11 203 9.6E-72 T 23-10-2018 STK_05900 60987104f9df9ed3ade0ddff0d0f0216 704 Pfam PF00271 Helicase conserved C-terminal domain 275 389 8.3E-9 T 23-10-2018 IPR001650 Helicase, C-terminal STK_05900 60987104f9df9ed3ade0ddff0d0f0216 704 SUPERFAMILY SSF158702 503 700 7.59E-58 T 23-10-2018 STK_05900 60987104f9df9ed3ade0ddff0d0f0216 704 Pfam PF00270 DEAD/DEAH box helicase 29 183 4.2E-24 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 STK_05900 60987104f9df9ed3ade0ddff0d0f0216 704 SUPERFAMILY SSF46785 420 502 7.89E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_05900 60987104f9df9ed3ade0ddff0d0f0216 704 Gene3D G3DSA:1.10.3380.30 427 645 1.4E-62 T 23-10-2018 STK_05900 60987104f9df9ed3ade0ddff0d0f0216 704 SMART SM00490 300 389 3.7E-16 T 23-10-2018 IPR001650 Helicase, C-terminal STK_05900 60987104f9df9ed3ade0ddff0d0f0216 704 Hamap MF_00442 ATP-dependent DNA helicase Hel308 [hel308]. 12 701 29.381 T 23-10-2018 IPR022965 ATP-dependent DNA helicase Hel308 GO:0004386 STK_05900 60987104f9df9ed3ade0ddff0d0f0216 704 Gene3D G3DSA:1.10.150.20 647 702 2.1E-25 T 23-10-2018 STK_05900 60987104f9df9ed3ade0ddff0d0f0216 704 SMART SM00487 23 212 8.6E-31 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain STK_05900 60987104f9df9ed3ade0ddff0d0f0216 704 Gene3D G3DSA:3.40.50.300 211 415 5.1E-60 T 23-10-2018 STK_24810 a718ebd2c8504654c393bf4ae40db150 501 PIRSF PIRSF006060 1 501 5.3E-38 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_24810 a718ebd2c8504654c393bf4ae40db150 501 Gene3D G3DSA:1.20.1740.10 15 487 1.9E-10 T 23-10-2018 STK_24810 a718ebd2c8504654c393bf4ae40db150 501 Pfam PF13520 Amino acid permease 19 468 5.1E-18 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_04720 18a73e44bec7bf5ca0d72a4771362858 151 Hamap MF_01224_A Cyclic pyranopterin monophosphate synthase [moaC]. 1 146 36.83 T 23-10-2018 IPR023047 Probable cyclic pyranopterin monophosphate synthase accessory protein, archaea KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823 STK_04720 18a73e44bec7bf5ca0d72a4771362858 151 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 3 135 8.0E-51 T 23-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 STK_04720 18a73e44bec7bf5ca0d72a4771362858 151 SUPERFAMILY SSF55040 3 145 1.02E-47 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 STK_04720 18a73e44bec7bf5ca0d72a4771362858 151 Pfam PF01967 MoaC family 6 144 1.2E-46 T 23-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 STK_04720 18a73e44bec7bf5ca0d72a4771362858 151 Gene3D G3DSA:3.30.70.640 1 151 3.0E-63 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 STK_12300 f52fd0e89e1c678cd8e5bd74f859b0f5 200 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 5 190 3.5E-27 T 23-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 STK_12300 f52fd0e89e1c678cd8e5bd74f859b0f5 200 SUPERFAMILY SSF51366 3 194 8.57E-31 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 STK_12300 f52fd0e89e1c678cd8e5bd74f859b0f5 200 Gene3D G3DSA:3.20.20.70 2 197 1.0E-29 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_12300 f52fd0e89e1c678cd8e5bd74f859b0f5 200 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 2 196 23.172 T 23-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 STK_24920 006533ddb4645f6d8ba2638452d7364b 1288 Gene3D G3DSA:2.60.40.10 1129 1223 3.0E-12 T 23-10-2018 IPR013783 Immunoglobulin-like fold STK_24920 006533ddb4645f6d8ba2638452d7364b 1288 Pfam PF09286 Pro-kumamolisin, activation domain 36 168 3.7E-23 T 23-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 STK_24920 006533ddb4645f6d8ba2638452d7364b 1288 Gene3D G3DSA:3.40.50.200 193 564 1.5E-82 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 STK_24920 006533ddb4645f6d8ba2638452d7364b 1288 Pfam PF00082 Subtilase family 312 514 2.5E-7 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 STK_24920 006533ddb4645f6d8ba2638452d7364b 1288 SMART SM00944 34 174 9.6E-43 T 23-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 STK_24920 006533ddb4645f6d8ba2638452d7364b 1288 PIRSF PIRSF032623 1 1288 0.0 T 23-10-2018 IPR017001 Peptidase S53, physarolisin II, archaeal-type STK_24920 006533ddb4645f6d8ba2638452d7364b 1288 SUPERFAMILY SSF54897 30 160 2.04E-21 T 23-10-2018 STK_24920 006533ddb4645f6d8ba2638452d7364b 1288 SUPERFAMILY SSF52743 201 561 4.45E-72 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 STK_24920 006533ddb4645f6d8ba2638452d7364b 1288 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 481 491 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site STK_23380 50b76bcbea55c79847f450444e51b36d 159 TIGRFAM TIGR03684 arCOG00985: arCOG04150 universal archaeal PUA-domain protein 3 149 2.9E-51 T 23-10-2018 IPR022430 Conserved hypothetical protein CHP03684 STK_23380 50b76bcbea55c79847f450444e51b36d 159 PIRSF PIRSF005067 1 154 4.2E-42 T 23-10-2018 IPR016437 MCT-1/Tma20 STK_23380 50b76bcbea55c79847f450444e51b36d 159 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 50 144 5.1E-17 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 STK_23380 50b76bcbea55c79847f450444e51b36d 159 SUPERFAMILY SSF88697 68 150 2.38E-19 T 23-10-2018 IPR015947 PUA-like superfamily STK_23380 50b76bcbea55c79847f450444e51b36d 159 Gene3D G3DSA:3.10.450.120 1 65 4.2E-8 T 23-10-2018 STK_23380 50b76bcbea55c79847f450444e51b36d 159 Pfam PF09183 Domain of unknown function (DUF1947) 2 63 7.4E-24 T 23-10-2018 IPR015266 Domain of unknown function DUF1947 STK_23380 50b76bcbea55c79847f450444e51b36d 159 SUPERFAMILY SSF88802 2 65 1.5E-20 T 23-10-2018 STK_23380 50b76bcbea55c79847f450444e51b36d 159 SMART SM00359 69 143 2.1E-7 T 23-10-2018 IPR002478 PUA domain GO:0003723 STK_23380 50b76bcbea55c79847f450444e51b36d 159 Pfam PF01472 PUA domain 69 134 1.8E-14 T 23-10-2018 IPR002478 PUA domain GO:0003723 STK_23380 50b76bcbea55c79847f450444e51b36d 159 Gene3D G3DSA:2.30.130.10 68 150 2.9E-25 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 STK_06550 260d31404e071303a8e1e2347f434a03 280 Pfam PF00753 Metallo-beta-lactamase superfamily 30 83 7.4E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_06550 260d31404e071303a8e1e2347f434a03 280 SUPERFAMILY SSF56281 20 255 2.29E-29 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_06550 260d31404e071303a8e1e2347f434a03 280 Gene3D G3DSA:3.60.15.10 1 276 3.9E-74 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_23280 55b79950df4fca255a3d56466130624b 291 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 2 282 2.7E-90 T 23-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 STK_23280 55b79950df4fca255a3d56466130624b 291 Pfam PF00294 pfkB family carbohydrate kinase 2 273 1.6E-57 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB STK_23280 55b79950df4fca255a3d56466130624b 291 PRINTS PR00990 Ribokinase signature 31 50 2.2E-29 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 STK_23280 55b79950df4fca255a3d56466130624b 291 PRINTS PR00990 Ribokinase signature 102 115 2.2E-29 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 STK_23280 55b79950df4fca255a3d56466130624b 291 PRINTS PR00990 Ribokinase signature 202 213 2.2E-29 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 STK_23280 55b79950df4fca255a3d56466130624b 291 PRINTS PR00990 Ribokinase signature 4 25 2.2E-29 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 STK_23280 55b79950df4fca255a3d56466130624b 291 PRINTS PR00990 Ribokinase signature 163 178 2.2E-29 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 STK_23280 55b79950df4fca255a3d56466130624b 291 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 231 244 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 STK_23280 55b79950df4fca255a3d56466130624b 291 Hamap MF_01987 Ribokinase [rbsK]. 1 284 20.585 T 23-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 STK_23280 55b79950df4fca255a3d56466130624b 291 Gene3D G3DSA:3.40.1190.20 1 290 2.9E-84 T 23-10-2018 IPR029056 Ribokinase-like STK_23280 55b79950df4fca255a3d56466130624b 291 SUPERFAMILY SSF53613 2 274 5.14E-73 T 23-10-2018 IPR029056 Ribokinase-like STK_16180 e9be710f0b492cadb187b87a5ec155bb 158 Pfam PF10061 Uncharacterized conserved protein (DUF2299) 5 140 3.6E-49 T 23-10-2018 IPR018747 Protein of unknown function DUF2299 STK_16180 e9be710f0b492cadb187b87a5ec155bb 158 Gene3D G3DSA:3.30.1460.10 1 146 9.3E-43 T 23-10-2018 STK_22250 9dcad4c79379c934a640c3ca4484de0d 368 Pfam PF02926 THUMP domain 31 150 9.3E-19 T 23-10-2018 IPR004114 THUMP domain GO:0003723 STK_22250 9dcad4c79379c934a640c3ca4484de0d 368 SMART SM00981 65 153 9.1E-21 T 23-10-2018 IPR004114 THUMP domain GO:0003723 STK_22250 9dcad4c79379c934a640c3ca4484de0d 368 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 5 359 6.1E-86 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 STK_22250 9dcad4c79379c934a640c3ca4484de0d 368 Gene3D G3DSA:3.30.2130.30 1 162 5.1E-33 T 23-10-2018 STK_22250 9dcad4c79379c934a640c3ca4484de0d 368 SUPERFAMILY SSF52402 163 319 2.43E-37 T 23-10-2018 STK_22250 9dcad4c79379c934a640c3ca4484de0d 368 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 163 353 1.5E-51 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 STK_22250 9dcad4c79379c934a640c3ca4484de0d 368 Gene3D G3DSA:3.40.50.620 163 367 3.6E-51 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_22250 9dcad4c79379c934a640c3ca4484de0d 368 SUPERFAMILY SSF143437 3 161 1.12E-37 T 23-10-2018 STK_22250 9dcad4c79379c934a640c3ca4484de0d 368 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 368 117.646 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 STK_13540 cf415f7a14e5bcea27209b0814f9af2e 433 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 4 413 38.118 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 STK_13540 cf415f7a14e5bcea27209b0814f9af2e 433 Gene3D G3DSA:3.90.1150.10 278 426 9.3E-52 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 STK_13540 cf415f7a14e5bcea27209b0814f9af2e 433 Gene3D G3DSA:3.40.640.10 40 277 1.3E-71 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 STK_13540 cf415f7a14e5bcea27209b0814f9af2e 433 PIRSF PIRSF000412 1 423 1.4E-137 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 STK_13540 cf415f7a14e5bcea27209b0814f9af2e 433 Pfam PF00464 Serine hydroxymethyltransferase 12 385 1.4E-67 T 23-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 STK_13540 cf415f7a14e5bcea27209b0814f9af2e 433 SUPERFAMILY SSF53383 10 414 9.96E-123 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase STK_13540 cf415f7a14e5bcea27209b0814f9af2e 433 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 220 236 - T 23-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 STK_03940 ee9f55988aed2c0f39f4cf7fcec56e21 155 Gene3D G3DSA:3.40.50.960 1 146 1.8E-33 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 STK_03940 ee9f55988aed2c0f39f4cf7fcec56e21 155 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 1 141 22.842 T 23-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 STK_03940 ee9f55988aed2c0f39f4cf7fcec56e21 155 SUPERFAMILY SSF52121 4 142 8.11E-42 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 STK_03940 ee9f55988aed2c0f39f4cf7fcec56e21 155 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 7 137 2.7E-35 T 23-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 STK_03940 ee9f55988aed2c0f39f4cf7fcec56e21 155 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 7 140 8.3E-42 T 23-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 STK_15240 39036f01c12bed3de3261ef4e51486f3 142 PRINTS PR01438 Universal stress protein signature 120 142 1.8E-21 T 23-10-2018 IPR006015 Universal stress protein A STK_15240 39036f01c12bed3de3261ef4e51486f3 142 PRINTS PR01438 Universal stress protein signature 102 114 1.8E-21 T 23-10-2018 IPR006015 Universal stress protein A STK_15240 39036f01c12bed3de3261ef4e51486f3 142 PRINTS PR01438 Universal stress protein signature 2 20 1.8E-21 T 23-10-2018 IPR006015 Universal stress protein A STK_15240 39036f01c12bed3de3261ef4e51486f3 142 Pfam PF00582 Universal stress protein family 1 142 1.8E-39 T 23-10-2018 IPR006016 UspA STK_15240 39036f01c12bed3de3261ef4e51486f3 142 Gene3D G3DSA:3.40.50.620 1 142 1.6E-41 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_15240 39036f01c12bed3de3261ef4e51486f3 142 SUPERFAMILY SSF52402 2 142 8.37E-40 T 23-10-2018 STK_15240 39036f01c12bed3de3261ef4e51486f3 142 PIRSF PIRSF006276 1 142 3.9E-19 T 23-10-2018 IPR006015 Universal stress protein A STK_24900 b21b37b5ca495d718b9acdebdce478b8 685 SUPERFAMILY SSF56003 120 684 1.23E-133 T 23-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 STK_24900 b21b37b5ca495d718b9acdebdce478b8 685 SMART SM01008 10 119 3.1E-26 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead STK_24900 b21b37b5ca495d718b9acdebdce478b8 685 Gene3D G3DSA:3.30.365.10 9 267 1.2E-84 T 23-10-2018 STK_24900 b21b37b5ca495d718b9acdebdce478b8 685 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 134 629 5.7E-115 T 23-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 STK_24900 b21b37b5ca495d718b9acdebdce478b8 685 Gene3D G3DSA:3.30.365.10 356 427 2.5E-33 T 23-10-2018 STK_24900 b21b37b5ca495d718b9acdebdce478b8 685 Gene3D G3DSA:3.30.365.10 428 518 2.5E-33 T 23-10-2018 STK_24900 b21b37b5ca495d718b9acdebdce478b8 685 SUPERFAMILY SSF54665 4 133 3.01E-30 T 23-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily STK_24900 b21b37b5ca495d718b9acdebdce478b8 685 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 10 119 7.6E-14 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead STK_24900 b21b37b5ca495d718b9acdebdce478b8 685 Gene3D G3DSA:3.30.365.10 120 345 1.2E-84 T 23-10-2018 STK_24900 b21b37b5ca495d718b9acdebdce478b8 685 Gene3D G3DSA:3.90.1170.50 25 119 1.2E-84 T 23-10-2018 STK_24900 b21b37b5ca495d718b9acdebdce478b8 685 Gene3D G3DSA:3.30.365.20 523 685 8.4E-35 T 23-10-2018 STK_08160 18c7ae5ea7eedeb119a21b42b1c50ff1 419 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 345 371 5.7E-4 T 23-10-2018 IPR001451 Hexapeptide repeat STK_08160 18c7ae5ea7eedeb119a21b42b1c50ff1 419 Gene3D G3DSA:2.160.10.10 288 415 6.9E-14 T 23-10-2018 STK_08160 18c7ae5ea7eedeb119a21b42b1c50ff1 419 SUPERFAMILY SSF53448 8 366 1.43E-63 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_08160 18c7ae5ea7eedeb119a21b42b1c50ff1 419 Pfam PF00483 Nucleotidyl transferase 10 260 7.1E-42 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 STK_08160 18c7ae5ea7eedeb119a21b42b1c50ff1 419 Gene3D G3DSA:3.90.550.10 3 279 1.7E-63 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_23620 7a8569c1f9c1f46779a7168b45e774fa 130 SUPERFAMILY SSF52402 2 130 4.54E-30 T 23-10-2018 STK_23620 7a8569c1f9c1f46779a7168b45e774fa 130 Pfam PF00582 Universal stress protein family 2 130 8.3E-30 T 23-10-2018 IPR006016 UspA STK_23620 7a8569c1f9c1f46779a7168b45e774fa 130 PRINTS PR01438 Universal stress protein signature 108 130 3.7E-10 T 23-10-2018 IPR006015 Universal stress protein A STK_23620 7a8569c1f9c1f46779a7168b45e774fa 130 PRINTS PR01438 Universal stress protein signature 90 102 3.7E-10 T 23-10-2018 IPR006015 Universal stress protein A STK_23620 7a8569c1f9c1f46779a7168b45e774fa 130 Gene3D G3DSA:3.40.50.620 1 130 1.2E-30 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_12620 fdde6aae60c206936c08fec1a9b42078 628 Gene3D G3DSA:3.30.1360.30 275 407 3.7E-44 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 STK_12620 fdde6aae60c206936c08fec1a9b42078 628 Pfam PF02637 GatB domain 486 627 1.6E-25 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 STK_12620 fdde6aae60c206936c08fec1a9b42078 628 Gene3D G3DSA:1.10.10.410 569 628 1.8E-8 T 23-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal STK_12620 fdde6aae60c206936c08fec1a9b42078 628 Pfam PF02938 GAD domain 299 389 8.7E-12 T 23-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 STK_12620 fdde6aae60c206936c08fec1a9b42078 628 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 286 409 8.0E-67 T 23-10-2018 STK_12620 fdde6aae60c206936c08fec1a9b42078 628 SMART SM00845 486 627 9.5E-29 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 STK_12620 fdde6aae60c206936c08fec1a9b42078 628 Pfam PF02934 GatB/GatE catalytic domain 12 448 1.7E-71 T 23-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 STK_12620 fdde6aae60c206936c08fec1a9b42078 628 SUPERFAMILY SSF55931 2 456 7.85E-101 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 STK_12620 fdde6aae60c206936c08fec1a9b42078 628 Hamap MF_00588 Glutamyl-tRNA(Gln) amidotransferase subunit E [gatE]. 1 628 300.355 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 STK_12620 fdde6aae60c206936c08fec1a9b42078 628 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 176 190 - T 23-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 STK_12620 fdde6aae60c206936c08fec1a9b42078 628 SUPERFAMILY SSF55261 281 407 4.91E-46 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 STK_12620 fdde6aae60c206936c08fec1a9b42078 628 Gene3D G3DSA:1.10.150.380 456 551 4.1E-17 T 23-10-2018 STK_12620 fdde6aae60c206936c08fec1a9b42078 628 SUPERFAMILY SSF89095 482 627 6.02E-21 T 23-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 STK_12620 fdde6aae60c206936c08fec1a9b42078 628 TIGRFAM TIGR00134 gatE_arch: glutamyl-tRNA(Gln) amidotransferase, subunit E 4 627 1.1E-208 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 STK_18030 e6eb01b10001813408c592b182d5af17 621 Pfam PF00501 AMP-binding enzyme 72 501 2.4E-72 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 STK_18030 e6eb01b10001813408c592b182d5af17 621 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 12 64 2.0E-14 T 23-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 STK_18030 e6eb01b10001813408c592b182d5af17 621 Pfam PF13193 AMP-binding enzyme C-terminal domain 509 583 5.6E-14 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain STK_18030 e6eb01b10001813408c592b182d5af17 621 ProSitePatterns PS00455 Putative AMP-binding domain signature. 240 251 - T 23-10-2018 IPR020845 AMP-binding, conserved site STK_18030 e6eb01b10001813408c592b182d5af17 621 SUPERFAMILY SSF56801 5 613 1.11E-131 T 23-10-2018 STK_18030 e6eb01b10001813408c592b182d5af17 621 Gene3D G3DSA:3.30.300.30 496 620 5.6E-19 T 23-10-2018 STK_18030 e6eb01b10001813408c592b182d5af17 621 Gene3D G3DSA:3.40.50.12780 37 495 2.1E-87 T 23-10-2018 STK_11005 91e16427f8a9e772155640eeaebf0dc5 78 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 2 43 1.6E-18 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_11005 91e16427f8a9e772155640eeaebf0dc5 78 SMART SM00966 3 48 8.4E-13 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_11005 91e16427f8a9e772155640eeaebf0dc5 78 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 3 44 1.9E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_11005 91e16427f8a9e772155640eeaebf0dc5 78 SUPERFAMILY SSF89447 2 43 7.32E-12 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily STK_11005 91e16427f8a9e772155640eeaebf0dc5 78 Gene3D G3DSA:2.10.260.10 1 47 1.5E-12 T 23-10-2018 STK_17520 62716dc6eeb4ecac69c7efd518b2d99b 317 SUPERFAMILY SSF58113 94 231 3.14E-12 T 23-10-2018 STK_17520 62716dc6eeb4ecac69c7efd518b2d99b 317 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 42 231 0.003 T 23-10-2018 STK_17520 62716dc6eeb4ecac69c7efd518b2d99b 317 Gene3D G3DSA:1.20.5.1230 41 245 4.7E-14 T 23-10-2018 STK_17520 62716dc6eeb4ecac69c7efd518b2d99b 317 SUPERFAMILY SSF52980 226 316 1.34E-5 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 STK_05910 6683f977a0990896f25003cc66d047c6 521 Gene3D G3DSA:3.90.226.10 1 264 1.1E-97 T 23-10-2018 STK_05910 6683f977a0990896f25003cc66d047c6 521 SUPERFAMILY SSF52096 9 261 6.83E-78 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily STK_05910 6683f977a0990896f25003cc66d047c6 521 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 169 186 2.5E-5 T 23-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 STK_05910 6683f977a0990896f25003cc66d047c6 521 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 99 113 2.5E-5 T 23-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 STK_05910 6683f977a0990896f25003cc66d047c6 521 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 133 151 2.5E-5 T 23-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 STK_05910 6683f977a0990896f25003cc66d047c6 521 Gene3D G3DSA:3.90.226.10 265 521 7.2E-95 T 23-10-2018 STK_05910 6683f977a0990896f25003cc66d047c6 521 Pfam PF01039 Carboxyl transferase domain 33 519 9.7E-185 T 23-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 STK_05910 6683f977a0990896f25003cc66d047c6 521 SUPERFAMILY SSF52096 248 521 1.17E-91 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily STK_00260 2f0841c5ea7b052f4eaa8aa0891dab59 298 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 3 284 20.973 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 STK_00260 2f0841c5ea7b052f4eaa8aa0891dab59 298 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 7 291 2.9E-80 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 STK_00260 2f0841c5ea7b052f4eaa8aa0891dab59 298 Gene3D G3DSA:1.20.120.920 84 294 2.9E-48 T 23-10-2018 STK_00260 2f0841c5ea7b052f4eaa8aa0891dab59 298 Gene3D G3DSA:3.100.10.20 7 80 3.6E-10 T 23-10-2018 STK_00260 2f0841c5ea7b052f4eaa8aa0891dab59 298 Pfam PF01867 CRISPR associated protein Cas1 8 260 7.4E-56 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 STK_14810 9412f15d2a0621bc4d6ec8e22c69f30a 195 Pfam PF00156 Phosphoribosyl transferase domain 46 153 1.7E-21 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 STK_14810 9412f15d2a0621bc4d6ec8e22c69f30a 195 SUPERFAMILY SSF53271 5 192 1.31E-45 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like STK_14810 9412f15d2a0621bc4d6ec8e22c69f30a 195 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 7 167 1.5E-40 T 23-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 STK_14810 9412f15d2a0621bc4d6ec8e22c69f30a 195 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 195 23.843 T 23-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 STK_14810 9412f15d2a0621bc4d6ec8e22c69f30a 195 Gene3D G3DSA:3.40.50.2020 1 194 8.5E-58 T 23-10-2018 STK_18550 9d0771ab106b28b6d315e7ef10a7ee27 180 Pfam PF04173 TQO small subunit DoxD 16 180 1.2E-69 T 23-10-2018 IPR007301 TQO small subunit DoxD KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 STK_21310 57890ba80bc3271c109fe22943db0b4d 162 Gene3D G3DSA:2.60.120.630 2 142 2.1E-50 T 23-10-2018 IPR023131 Mth639-like domain superfamily STK_21310 57890ba80bc3271c109fe22943db0b4d 162 Pfam PF04027 Domain of unknown function (DUF371) 7 136 8.6E-50 T 23-10-2018 IPR007171 Protein of unknown function DUF371 STK_24200 63062f69d20066be70ee4daff2d66d63 429 Gene3D G3DSA:3.30.300.30 337 428 2.4E-16 T 23-10-2018 STK_24200 63062f69d20066be70ee4daff2d66d63 429 Pfam PF14535 AMP-binding enzyme C-terminal domain 345 426 2.6E-13 T 23-10-2018 IPR028154 AMP-dependent ligase, C-terminal STK_24200 63062f69d20066be70ee4daff2d66d63 429 Gene3D G3DSA:3.40.50.12780 5 336 8.9E-110 T 23-10-2018 STK_24200 63062f69d20066be70ee4daff2d66d63 429 SUPERFAMILY SSF56801 46 388 1.19E-50 T 23-10-2018 STK_24200 63062f69d20066be70ee4daff2d66d63 429 Pfam PF00501 AMP-binding enzyme 89 298 4.5E-16 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 STK_22670 6866bc377cd4a6e5d006ce5b9d67e60d 287 Gene3D G3DSA:3.40.50.720 1 239 7.1E-72 T 23-10-2018 STK_22670 6866bc377cd4a6e5d006ce5b9d67e60d 287 Pfam PF00899 ThiF family 4 232 7.4E-60 T 23-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 STK_22670 6866bc377cd4a6e5d006ce5b9d67e60d 287 SUPERFAMILY SSF69572 1 237 1.57E-77 T 23-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 STK_05390 ac8039e5d7f2ef14ffff45904fa617fe 183 Gene3D G3DSA:3.40.50.10240 18 95 1.8E-6 T 23-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 STK_05390 ac8039e5d7f2ef14ffff45904fa617fe 183 SUPERFAMILY SSF63999 4 138 1.02E-15 T 23-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 STK_05390 ac8039e5d7f2ef14ffff45904fa617fe 183 Hamap MF_02131 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase [mptE]. 3 182 28.822 T 23-10-2018 IPR027510 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, MptE GO:0003848|GO:0005524 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 STK_05390 ac8039e5d7f2ef14ffff45904fa617fe 183 Pfam PF01973 Protein of unknown function DUF115 14 142 4.2E-26 T 23-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like STK_14490 9fa94cc470fc5ea7ec913d6fab6d7497 265 PIRSF PIRSF006230 1 259 1.0E-61 T 23-10-2018 IPR016478 GTPase, MTG1 STK_14490 9fa94cc470fc5ea7ec913d6fab6d7497 265 Pfam PF03193 RsgA GTPase 36 156 2.8E-12 T 23-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 STK_14490 9fa94cc470fc5ea7ec913d6fab6d7497 265 SUPERFAMILY SSF52540 2 164 1.84E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_14490 9fa94cc470fc5ea7ec913d6fab6d7497 265 Gene3D G3DSA:1.10.1580.10 167 248 2.0E-9 T 23-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily STK_14490 9fa94cc470fc5ea7ec913d6fab6d7497 265 Gene3D G3DSA:3.40.50.300 1 160 8.7E-40 T 23-10-2018 STK_16380 e33d5ee991053236428e0f269fd24984 327 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 317 1.2E-46 T 23-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 STK_16380 e33d5ee991053236428e0f269fd24984 327 Gene3D G3DSA:1.20.1090.10 149 327 4.2E-33 T 23-10-2018 STK_16380 e33d5ee991053236428e0f269fd24984 327 Gene3D G3DSA:3.40.50.1970 1 146 5.9E-21 T 23-10-2018 STK_16380 e33d5ee991053236428e0f269fd24984 327 SUPERFAMILY SSF56796 7 325 1.96E-57 T 23-10-2018 STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 Gene3D G3DSA:3.30.390.30 340 455 2.4E-29 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 Gene3D G3DSA:3.50.50.60 3 318 1.4E-104 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 318 5.6E-54 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 38 48 - T 23-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 342 449 1.2E-16 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 285 307 3.2E-28 T 23-10-2018 STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 273 3.2E-28 T 23-10-2018 STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 130 148 3.2E-28 T 23-10-2018 STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 3.2E-28 T 23-10-2018 STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 3.2E-28 T 23-10-2018 STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 SUPERFAMILY SSF51905 1 328 1.67E-47 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 PIRSF PIRSF000350 1 439 2.8E-59 T 23-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 SUPERFAMILY SSF55424 339 454 2.75E-26 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 133 142 6.5E-47 T 23-10-2018 STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 258 272 6.5E-47 T 23-10-2018 STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 425 445 6.5E-47 T 23-10-2018 STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 338 359 6.5E-47 T 23-10-2018 STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 403 418 6.5E-47 T 23-10-2018 STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 6.5E-47 T 23-10-2018 STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 300 307 6.5E-47 T 23-10-2018 STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 6.5E-47 T 23-10-2018 STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 171 196 6.5E-47 T 23-10-2018 STK_06870 ea0ce139f7db28f110356e361eb0a84a 455 Gene3D G3DSA:3.50.50.60 142 266 1.4E-104 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_06840 11c174c6e3399bb6ebeb7d541884c0fb 205 SUPERFAMILY SSF48613 2 203 4.15E-48 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 STK_06840 11c174c6e3399bb6ebeb7d541884c0fb 205 Gene3D G3DSA:1.20.910.10 7 204 4.5E-52 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 STK_06840 11c174c6e3399bb6ebeb7d541884c0fb 205 Pfam PF03070 TENA/THI-4/PQQC family 14 204 2.0E-28 T 23-10-2018 IPR004305 Thiaminase-2/PQQC STK_26110 0f48e97015a94bb508a9aaa043476c09 599 Pfam PF09286 Pro-kumamolisin, activation domain 43 194 9.3E-28 T 23-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 STK_26110 0f48e97015a94bb508a9aaa043476c09 599 SUPERFAMILY SSF52743 231 593 1.31E-44 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 STK_26110 0f48e97015a94bb508a9aaa043476c09 599 SUPERFAMILY SSF54897 37 195 2.89E-22 T 23-10-2018 STK_26110 0f48e97015a94bb508a9aaa043476c09 599 Gene3D G3DSA:3.40.50.200 221 592 4.7E-54 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 STK_26110 0f48e97015a94bb508a9aaa043476c09 599 SMART SM00944 41 195 1.6E-38 T 23-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 STK_04750 6705e35ef9b32e154b35aa44e37541a4 327 Gene3D G3DSA:3.40.50.300 2 162 2.6E-54 T 23-10-2018 STK_04750 6705e35ef9b32e154b35aa44e37541a4 327 Gene3D G3DSA:1.10.8.60 164 225 3.5E-21 T 23-10-2018 STK_04750 6705e35ef9b32e154b35aa44e37541a4 327 SUPERFAMILY SSF48019 228 319 1.96E-23 T 23-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 STK_04750 6705e35ef9b32e154b35aa44e37541a4 327 Gene3D G3DSA:1.20.272.10 227 322 5.0E-36 T 23-10-2018 STK_04750 6705e35ef9b32e154b35aa44e37541a4 327 Pfam PF08542 Replication factor C C-terminal domain 228 315 7.0E-25 T 23-10-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 STK_04750 6705e35ef9b32e154b35aa44e37541a4 327 SUPERFAMILY SSF52540 7 211 1.65E-54 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_04750 6705e35ef9b32e154b35aa44e37541a4 327 Hamap MF_01509 Replication factor C small subunit [rfcS]. 5 320 50.963 T 23-10-2018 IPR023748 Replication factor C small subunit, archaeal GO:0003689|GO:0005524|GO:0005663|GO:0006260 STK_04750 6705e35ef9b32e154b35aa44e37541a4 327 SMART SM00382 39 166 2.7E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_04750 6705e35ef9b32e154b35aa44e37541a4 327 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 43 156 2.9E-15 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_26050 278ce1939607d6a718e3594258b36638 330 SMART SM00829 9 328 1.9E-12 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 STK_26050 278ce1939607d6a718e3594258b36638 330 SUPERFAMILY SSF51735 137 295 1.39E-37 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_26050 278ce1939607d6a718e3594258b36638 330 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 132 1.1E-26 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 STK_26050 278ce1939607d6a718e3594258b36638 330 Gene3D G3DSA:3.90.180.10 1 330 6.3E-90 T 23-10-2018 STK_26050 278ce1939607d6a718e3594258b36638 330 Pfam PF00107 Zinc-binding dehydrogenase 176 294 2.6E-23 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 STK_26050 278ce1939607d6a718e3594258b36638 330 SUPERFAMILY SSF50129 2 176 2.13E-48 T 23-10-2018 IPR011032 GroES-like superfamily STK_03455 162e65047ec3d29c713502ec0b19d8d8 61 Gene3D G3DSA:2.20.25.30 1 55 1.8E-23 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_03455 162e65047ec3d29c713502ec0b19d8d8 61 Pfam PF01907 Ribosomal protein L37e 1 54 5.8E-26 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_03455 162e65047ec3d29c713502ec0b19d8d8 61 ProDom PD005132 RIBOSOMAL RRNA-BINDING METAL-BINDING RNA-BINDING ZINC RIBONUCLEOPROTEIN ZINC-FINGER L37 60S L37E 8 50 2.0E-18 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_03455 162e65047ec3d29c713502ec0b19d8d8 61 ProSitePatterns PS01077 Ribosomal protein L37e signature. 3 23 - T 23-10-2018 IPR018267 Ribosomal protein L37e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_03455 162e65047ec3d29c713502ec0b19d8d8 61 Hamap MF_00547 50S ribosomal protein L37e [rpl37e]. 1 54 21.624 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_03455 162e65047ec3d29c713502ec0b19d8d8 61 SUPERFAMILY SSF57829 1 55 2.38E-22 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 STK_21440 a6870c4a2f2af4cfa0eb2c0379cf4c00 104 SUPERFAMILY SSF46785 4 102 1.14E-30 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_21440 a6870c4a2f2af4cfa0eb2c0379cf4c00 104 Gene3D G3DSA:2.20.28.10 7 103 5.6E-28 T 23-10-2018 STK_05880 ce2285dce0444217147efe415a307fc7 201 Pfam PF01865 Protein of unknown function DUF47 15 197 1.5E-11 T 23-10-2018 IPR018445 Putative phosphate transport regulator STK_05880 ce2285dce0444217147efe415a307fc7 201 Gene3D G3DSA:1.20.58.220 1 197 1.3E-24 T 23-10-2018 IPR038078 PhoU-like domain superfamily STK_09660 90bd85757151a67ee247edba10395d97 540 Gene3D G3DSA:3.40.50.800 426 538 3.1E-31 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily STK_09660 90bd85757151a67ee247edba10395d97 540 SUPERFAMILY SSF52954 421 528 3.32E-30 T 23-10-2018 STK_09660 90bd85757151a67ee247edba10395d97 540 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 3 528 29.933 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 STK_09660 90bd85757151a67ee247edba10395d97 540 Pfam PF03129 Anticodon binding domain 435 524 2.7E-21 T 23-10-2018 IPR004154 Anticodon-binding STK_09660 90bd85757151a67ee247edba10395d97 540 SUPERFAMILY SSF55681 134 420 5.18E-85 T 23-10-2018 STK_09660 90bd85757151a67ee247edba10395d97 540 SUPERFAMILY SSF55186 15 132 3.14E-8 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 STK_09660 90bd85757151a67ee247edba10395d97 540 PRINTS PR01047 Threonyl-tRNA synthetase signature 254 277 7.8E-52 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 STK_09660 90bd85757151a67ee247edba10395d97 540 PRINTS PR01047 Threonyl-tRNA synthetase signature 358 386 7.8E-52 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 STK_09660 90bd85757151a67ee247edba10395d97 540 PRINTS PR01047 Threonyl-tRNA synthetase signature 428 440 7.8E-52 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 STK_09660 90bd85757151a67ee247edba10395d97 540 PRINTS PR01047 Threonyl-tRNA synthetase signature 221 249 7.8E-52 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 STK_09660 90bd85757151a67ee247edba10395d97 540 PRINTS PR01047 Threonyl-tRNA synthetase signature 401 414 7.8E-52 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 STK_09660 90bd85757151a67ee247edba10395d97 540 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 215 422 1.2E-40 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_09660 90bd85757151a67ee247edba10395d97 540 Gene3D G3DSA:3.30.930.10 113 425 3.2E-118 T 23-10-2018 STK_09660 90bd85757151a67ee247edba10395d97 540 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 100 525 1.2E-165 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 STK_14050 6ce5ebd67750b2b77a2bca059536f51d 300 Gene3D G3DSA:1.10.10.10 3 80 4.7E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_14050 6ce5ebd67750b2b77a2bca059536f51d 300 Pfam PF00571 CBS domain 175 228 3.5E-11 T 23-10-2018 IPR000644 CBS domain STK_14050 6ce5ebd67750b2b77a2bca059536f51d 300 Pfam PF00571 CBS domain 237 292 2.6E-11 T 23-10-2018 IPR000644 CBS domain STK_14050 6ce5ebd67750b2b77a2bca059536f51d 300 SUPERFAMILY SSF54631 169 293 3.28E-32 T 23-10-2018 STK_14050 6ce5ebd67750b2b77a2bca059536f51d 300 SMART SM00116 244 292 1.2E-9 T 23-10-2018 IPR000644 CBS domain STK_14050 6ce5ebd67750b2b77a2bca059536f51d 300 SMART SM00116 181 229 5.4E-10 T 23-10-2018 IPR000644 CBS domain STK_14050 6ce5ebd67750b2b77a2bca059536f51d 300 SUPERFAMILY SSF46785 4 77 2.23E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_14050 6ce5ebd67750b2b77a2bca059536f51d 300 Gene3D G3DSA:3.10.580.10 167 292 5.2E-31 T 23-10-2018 STK_14050 6ce5ebd67750b2b77a2bca059536f51d 300 PIRSF PIRSF005063 1 299 3.6E-125 T 23-10-2018 IPR016436 Uncharacterised conserved protein UCP005063, CBS-type STK_14050 6ce5ebd67750b2b77a2bca059536f51d 300 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 3 77 2.8E-34 T 23-10-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 STK_22110 7bad5a003efb0c93ffa12febcb199b3f 377 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 270 2.2E-26 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 STK_22110 7bad5a003efb0c93ffa12febcb199b3f 377 SUPERFAMILY SSF51905 1 299 1.85E-25 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_22110 7bad5a003efb0c93ffa12febcb199b3f 377 Gene3D G3DSA:3.50.50.100 1 367 8.3E-75 T 23-10-2018 STK_24550 8bfd8a5e4baaceeb85746ccad879c2fd 438 PIRSF PIRSF006060 2 436 5.7E-15 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_24550 8bfd8a5e4baaceeb85746ccad879c2fd 438 Pfam PF00324 Amino acid permease 25 323 2.0E-10 T 23-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 STK_24550 8bfd8a5e4baaceeb85746ccad879c2fd 438 Gene3D G3DSA:1.20.1740.10 39 429 5.3E-8 T 23-10-2018 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 3 1045 14.315 T 23-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1031 0.0 T 23-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 SUPERFAMILY SSF52440 2 124 2.01E-42 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 SUPERFAMILY SSF56059 669 926 1.24E-82 T 23-10-2018 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 Gene3D G3DSA:3.30.470.20 118 399 6.0E-110 T 23-10-2018 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 127 331 2.3E-64 T 23-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 669 858 1.6E-26 T 23-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 SUPERFAMILY SSF48108 392 548 4.71E-45 T 23-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 Gene3D G3DSA:1.10.1030.10 405 547 9.6E-42 T 23-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 Gene3D G3DSA:3.40.50.20 1 114 5.8E-45 T 23-10-2018 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 833 840 - T 23-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 424 541 1.1E-33 T 23-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 SUPERFAMILY SSF56059 127 397 8.59E-97 T 23-10-2018 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 SMART SM01096 420 541 3.4E-56 T 23-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 Gene3D G3DSA:3.40.50.20 551 658 2.7E-26 T 23-10-2018 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 SUPERFAMILY SSF52440 554 671 4.6E-32 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 Gene3D G3DSA:3.30.470.20 663 923 1.8E-88 T 23-10-2018 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 Gene3D G3DSA:3.30.1490.20 682 751 1.8E-88 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 705 719 - T 23-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 166 178 1.4E-56 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 202 221 1.4E-56 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 237 254 1.4E-56 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 294 323 1.4E-56 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 376 394 1.4E-56 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 46 56 1.4E-56 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_15040 353db9b11089c7bf7b9b19f03f85d82a 1049 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 17 31 1.4E-56 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_25950 5910e63cc9d2a369a95b50cbefb45992 579 SUPERFAMILY SSF81442 23 507 1.83E-80 T 23-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_25950 5910e63cc9d2a369a95b50cbefb45992 579 Gene3D G3DSA:1.20.210.10 11 513 1.6E-79 T 23-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_25950 5910e63cc9d2a369a95b50cbefb45992 579 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 38 471 3.8E-75 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_25950 5910e63cc9d2a369a95b50cbefb45992 579 PRINTS PR01165 Cytochrome c oxidase subunit I signature 103 127 4.4E-12 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_25950 5910e63cc9d2a369a95b50cbefb45992 579 PRINTS PR01165 Cytochrome c oxidase subunit I signature 76 99 4.4E-12 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_25950 5910e63cc9d2a369a95b50cbefb45992 579 PRINTS PR01165 Cytochrome c oxidase subunit I signature 378 397 4.4E-12 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_25950 5910e63cc9d2a369a95b50cbefb45992 579 PRINTS PR01165 Cytochrome c oxidase subunit I signature 242 263 4.4E-12 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_25950 5910e63cc9d2a369a95b50cbefb45992 579 PRINTS PR01165 Cytochrome c oxidase subunit I signature 288 303 4.4E-12 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_13030 b6f615f277cf7ba0aae1944336cb4ce3 157 Pfam PF05942 Archaeal PaREP1/PaREP8 family 37 148 5.0E-35 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_13030 b6f615f277cf7ba0aae1944336cb4ce3 157 Gene3D G3DSA:1.20.120.330 37 156 1.2E-36 T 23-10-2018 STK_13030 b6f615f277cf7ba0aae1944336cb4ce3 157 SUPERFAMILY SSF158372 13 60 8.63E-5 T 23-10-2018 IPR036809 AF1782-like superfamily STK_08860 9ef966d34eaaad7737397234530e9acc 240 Pfam PF00535 Glycosyl transferase family 2 4 136 5.9E-17 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 STK_08860 9ef966d34eaaad7737397234530e9acc 240 Gene3D G3DSA:3.90.550.10 1 227 6.7E-34 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_08860 9ef966d34eaaad7737397234530e9acc 240 SUPERFAMILY SSF53448 1 226 2.28E-29 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_18120 0bfe40c45ea6353915761ed78bd2e835 169 Gene3D G3DSA:3.40.50.1000 2 163 4.7E-6 T 23-10-2018 IPR023214 HAD superfamily STK_18120 0bfe40c45ea6353915761ed78bd2e835 169 SUPERFAMILY SSF56784 2 149 2.16E-6 T 23-10-2018 IPR036412 HAD-like superfamily STK_12950 bcde0c25b1a32f39c5aa47149e8c3bb0 387 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 233 253 8.1E-47 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 STK_12950 bcde0c25b1a32f39c5aa47149e8c3bb0 387 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 177 195 8.1E-47 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 STK_12950 bcde0c25b1a32f39c5aa47149e8c3bb0 387 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 43 63 8.1E-47 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 STK_12950 bcde0c25b1a32f39c5aa47149e8c3bb0 387 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 124 141 8.1E-47 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 STK_12950 bcde0c25b1a32f39c5aa47149e8c3bb0 387 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 357 380 8.1E-47 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 STK_12950 bcde0c25b1a32f39c5aa47149e8c3bb0 387 Hamap MF_00132 Type 2 DNA topoisomerase 6 subunit A [top6A]. 11 386 38.907 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 STK_12950 bcde0c25b1a32f39c5aa47149e8c3bb0 387 SUPERFAMILY SSF56726 76 386 8.24E-86 T 23-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 STK_12950 bcde0c25b1a32f39c5aa47149e8c3bb0 387 Gene3D G3DSA:3.40.1360.10 157 387 6.5E-87 T 23-10-2018 STK_12950 bcde0c25b1a32f39c5aa47149e8c3bb0 387 Pfam PF04406 Type IIB DNA topoisomerase 77 153 2.6E-20 T 23-10-2018 IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal GO:0003677|GO:0003824|GO:0005524|GO:0005694|GO:0006259 Reactome: R-HSA-912446 STK_12950 bcde0c25b1a32f39c5aa47149e8c3bb0 387 Gene3D G3DSA:1.10.10.10 1 156 1.2E-58 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_12950 bcde0c25b1a32f39c5aa47149e8c3bb0 387 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 259 275 8.2E-37 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 STK_12950 bcde0c25b1a32f39c5aa47149e8c3bb0 387 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 101 112 8.2E-37 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 STK_12950 bcde0c25b1a32f39c5aa47149e8c3bb0 387 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 130 147 8.2E-37 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 STK_12950 bcde0c25b1a32f39c5aa47149e8c3bb0 387 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 203 220 8.2E-37 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 STK_12950 bcde0c25b1a32f39c5aa47149e8c3bb0 387 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 227 248 8.2E-37 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 STK_12950 bcde0c25b1a32f39c5aa47149e8c3bb0 387 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 148 163 8.2E-37 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 STK_00170 9fa6b5b90b9bdf19fb97c999231d9fed 143 SUPERFAMILY SSF88723 4 134 1.32E-15 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_00170 9fa6b5b90b9bdf19fb97c999231d9fed 143 Pfam PF01850 PIN domain 5 134 4.3E-10 T 23-10-2018 IPR002716 PIN domain STK_00170 9fa6b5b90b9bdf19fb97c999231d9fed 143 Gene3D G3DSA:3.40.50.1010 4 141 4.0E-11 T 23-10-2018 STK_00030 76e71d57365c18fdf36ecb961de7aa2b 949 Gene3D G3DSA:3.40.50.300 48 248 1.1E-29 T 23-10-2018 STK_00030 76e71d57365c18fdf36ecb961de7aa2b 949 SMART SM00490 307 420 5.2E-11 T 23-10-2018 IPR001650 Helicase, C-terminal STK_00030 76e71d57365c18fdf36ecb961de7aa2b 949 SUPERFAMILY SSF52540 60 420 1.14E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_00030 76e71d57365c18fdf36ecb961de7aa2b 949 Gene3D G3DSA:3.40.50.300 291 449 3.5E-22 T 23-10-2018 STK_00030 76e71d57365c18fdf36ecb961de7aa2b 949 SMART SM00487 48 261 2.2E-16 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain STK_00030 76e71d57365c18fdf36ecb961de7aa2b 949 Pfam PF00270 DEAD/DEAH box helicase 54 234 3.4E-20 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 STK_00030 76e71d57365c18fdf36ecb961de7aa2b 949 Pfam PF00271 Helicase conserved C-terminal domain 310 419 8.6E-15 T 23-10-2018 IPR001650 Helicase, C-terminal STK_05470 732177df7b419018f96eb180b2595258 264 Pfam PF00459 Inositol monophosphatase family 20 214 2.8E-22 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 STK_05470 732177df7b419018f96eb180b2595258 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 172 193 8.8E-15 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 STK_05470 732177df7b419018f96eb180b2595258 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 35 55 8.8E-15 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 STK_05470 732177df7b419018f96eb180b2595258 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 78 94 8.8E-15 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 STK_05470 732177df7b419018f96eb180b2595258 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 57 73 8.8E-15 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 STK_05470 732177df7b419018f96eb180b2595258 264 Gene3D G3DSA:3.40.190.80 149 259 1.3E-12 T 23-10-2018 STK_05470 732177df7b419018f96eb180b2595258 264 SUPERFAMILY SSF56655 3 251 1.31E-42 T 23-10-2018 STK_05470 732177df7b419018f96eb180b2595258 264 Gene3D G3DSA:3.30.540.10 1 138 8.6E-24 T 23-10-2018 STK_26330 12526d10d78ecf0abcb51ec17d6eb48a 279 PIRSF PIRSF009226 1 279 1.2E-110 T 23-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 STK_26330 12526d10d78ecf0abcb51ec17d6eb48a 279 TIGRFAM TIGR01896 cas_AF1879: CRISPR-associated protein Cas4/Csa1, subtype I-A/APERN 7 278 1.3E-116 T 23-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 STK_26330 12526d10d78ecf0abcb51ec17d6eb48a 279 Pfam PF06023 CRISPR-associated exonuclease Csa1 5 277 6.4E-82 T 23-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 STK_26330 12526d10d78ecf0abcb51ec17d6eb48a 279 Gene3D G3DSA:3.90.320.10 153 279 1.4E-7 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal STK_09300 3488f39cd90fc44fc8e648d44aae58b2 210 SUPERFAMILY SSF51556 76 129 2.04E-6 T 23-10-2018 IPR032466 Metal-dependent hydrolase STK_09300 3488f39cd90fc44fc8e648d44aae58b2 210 Gene3D G3DSA:3.20.20.140 50 165 3.5E-7 T 23-10-2018 STK_04850 c82dcbfc10175a4ed813db0a6ac6f397 270 SUPERFAMILY SSF53167 8 269 1.01E-98 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 STK_04850 c82dcbfc10175a4ed813db0a6ac6f397 270 Gene3D G3DSA:3.40.50.1580 1 270 1.9E-107 T 23-10-2018 STK_04850 c82dcbfc10175a4ed813db0a6ac6f397 270 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 10 248 4.9E-104 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 STK_04850 c82dcbfc10175a4ed813db0a6ac6f397 270 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 56 96 - T 23-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 STK_04850 c82dcbfc10175a4ed813db0a6ac6f397 270 Pfam PF01048 Phosphorylase superfamily 10 248 1.0E-46 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 STK_04850 c82dcbfc10175a4ed813db0a6ac6f397 270 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 8 270 45.494 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 STK_24890 3c050c6898767e1219347130895920b9 291 PIRSF PIRSF000097 119 286 5.8E-16 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 STK_24890 3c050c6898767e1219347130895920b9 291 PIRSF PIRSF000097 8 122 1.8E-18 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 STK_24890 3c050c6898767e1219347130895920b9 291 Gene3D G3DSA:3.20.20.100 8 279 8.2E-82 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily STK_24890 3c050c6898767e1219347130895920b9 291 PRINTS PR00069 Aldo-keto reductase signature 204 228 8.6E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 STK_24890 3c050c6898767e1219347130895920b9 291 PRINTS PR00069 Aldo-keto reductase signature 44 68 8.6E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 STK_24890 3c050c6898767e1219347130895920b9 291 PRINTS PR00069 Aldo-keto reductase signature 130 147 8.6E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 STK_24890 3c050c6898767e1219347130895920b9 291 PRINTS PR00069 Aldo-keto reductase signature 167 196 8.6E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 STK_24890 3c050c6898767e1219347130895920b9 291 PRINTS PR00069 Aldo-keto reductase signature 100 118 8.6E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 STK_24890 3c050c6898767e1219347130895920b9 291 Pfam PF00248 Aldo/keto reductase family 15 207 1.6E-48 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain STK_24890 3c050c6898767e1219347130895920b9 291 Pfam PF00248 Aldo/keto reductase family 210 269 8.6E-10 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain STK_24890 3c050c6898767e1219347130895920b9 291 SUPERFAMILY SSF51430 11 279 5.89E-79 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily STK_15370 4e29247b4ddc059924357ee1a8af60fa 659 SUPERFAMILY SSF56059 461 659 2.65E-40 T 23-10-2018 STK_15370 4e29247b4ddc059924357ee1a8af60fa 659 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 147 284 7.4E-49 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain STK_15370 4e29247b4ddc059924357ee1a8af60fa 659 Gene3D G3DSA:3.40.50.720 1 127 9.3E-46 T 23-10-2018 STK_15370 4e29247b4ddc059924357ee1a8af60fa 659 Gene3D G3DSA:3.30.1490.20 479 546 8.7E-56 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 STK_15370 4e29247b4ddc059924357ee1a8af60fa 659 SMART SM00881 6 100 1.2E-39 T 23-10-2018 IPR003781 CoA-binding GO:0048037 STK_15370 4e29247b4ddc059924357ee1a8af60fa 659 Gene3D G3DSA:3.40.50.261 288 438 9.3E-32 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 STK_15370 4e29247b4ddc059924357ee1a8af60fa 659 Gene3D G3DSA:3.40.50.261 130 287 1.4E-52 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 STK_15370 4e29247b4ddc059924357ee1a8af60fa 659 Gene3D G3DSA:3.30.470.20 459 656 8.7E-56 T 23-10-2018 STK_15370 4e29247b4ddc059924357ee1a8af60fa 659 TIGRFAM TIGR02717 AcCoA-syn-alpha: acetyl coenzyme A synthetase (ADP forming), alpha domain 3 435 2.9E-172 T 23-10-2018 IPR014089 Acetate-CoA ligase [ADP-forming], alpha domain KEGG: 00010+6.2.1.13|KEGG: 00620+6.2.1.13|KEGG: 00640+6.2.1.13|MetaCyc: PWY-5483|MetaCyc: PWY-5535 STK_15370 4e29247b4ddc059924357ee1a8af60fa 659 SUPERFAMILY SSF52210 135 285 2.88E-38 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 STK_15370 4e29247b4ddc059924357ee1a8af60fa 659 Pfam PF13549 ATP-grasp domain 456 657 1.5E-49 T 23-10-2018 STK_15370 4e29247b4ddc059924357ee1a8af60fa 659 SUPERFAMILY SSF51735 2 134 6.4E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_15370 4e29247b4ddc059924357ee1a8af60fa 659 SUPERFAMILY SSF52210 289 439 7.2E-29 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 STK_15370 4e29247b4ddc059924357ee1a8af60fa 659 Pfam PF13380 CoA binding domain 10 132 4.4E-25 T 23-10-2018 IPR003781 CoA-binding GO:0048037 STK_25140 c65aad9066952f32361578c0ac8a16fd 263 Gene3D G3DSA:1.10.10.10 22 96 1.8E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_25140 c65aad9066952f32361578c0ac8a16fd 263 Pfam PF13412 Winged helix-turn-helix DNA-binding 22 66 2.3E-7 T 23-10-2018 STK_25140 c65aad9066952f32361578c0ac8a16fd 263 SUPERFAMILY SSF46785 23 92 1.3E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_25550 82c1e7cd3c42651b596dfddcf9e86560 285 Gene3D G3DSA:2.120.10.30 1 284 8.4E-98 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like STK_25550 82c1e7cd3c42651b596dfddcf9e86560 285 SUPERFAMILY SSF63829 11 282 1.72E-65 T 23-10-2018 STK_25550 82c1e7cd3c42651b596dfddcf9e86560 285 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 16 256 4.2E-77 T 23-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region STK_25550 82c1e7cd3c42651b596dfddcf9e86560 285 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 238 256 5.5E-47 T 23-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) STK_25550 82c1e7cd3c42651b596dfddcf9e86560 285 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 133 155 5.5E-47 T 23-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) STK_25550 82c1e7cd3c42651b596dfddcf9e86560 285 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 156 176 5.5E-47 T 23-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) STK_25550 82c1e7cd3c42651b596dfddcf9e86560 285 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 196 213 5.5E-47 T 23-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) STK_25550 82c1e7cd3c42651b596dfddcf9e86560 285 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 17 34 5.5E-47 T 23-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) STK_25550 82c1e7cd3c42651b596dfddcf9e86560 285 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 93 114 5.5E-47 T 23-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) STK_02200 0c5db2c58b118942c58b72566542fe0a 453 SUPERFAMILY SSF51905 97 321 7.3E-7 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_02200 0c5db2c58b118942c58b72566542fe0a 453 Gene3D G3DSA:1.10.10.1100 380 443 2.8E-12 T 23-10-2018 STK_02200 0c5db2c58b118942c58b72566542fe0a 453 Gene3D G3DSA:3.50.50.60 81 204 1.5E-5 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_02200 0c5db2c58b118942c58b72566542fe0a 453 Gene3D G3DSA:3.50.50.60 210 327 3.2E-6 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_02200 0c5db2c58b118942c58b72566542fe0a 453 Pfam PF04324 BFD-like [2Fe-2S] binding domain 386 436 3.6E-6 T 23-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain STK_05940 5222b6f9269ed6f1ad6b9f09ef24a30f 541 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 28 213 2.6E-14 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 STK_05940 5222b6f9269ed6f1ad6b9f09ef24a30f 541 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 337 519 2.5E-10 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 STK_05940 5222b6f9269ed6f1ad6b9f09ef24a30f 541 Gene3D G3DSA:1.10.3720.10 4 211 1.2E-14 T 23-10-2018 IPR035906 MetI-like superfamily STK_05940 5222b6f9269ed6f1ad6b9f09ef24a30f 541 Gene3D G3DSA:1.10.3720.10 319 525 4.2E-15 T 23-10-2018 IPR035906 MetI-like superfamily STK_05940 5222b6f9269ed6f1ad6b9f09ef24a30f 541 SUPERFAMILY SSF161098 10 205 5.23E-16 T 23-10-2018 IPR035906 MetI-like superfamily STK_05940 5222b6f9269ed6f1ad6b9f09ef24a30f 541 SUPERFAMILY SSF161098 328 516 1.44E-13 T 23-10-2018 IPR035906 MetI-like superfamily STK_13070 a534ccd1dcf2114a5edddcbcff2bb893 540 SUPERFAMILY SSF52540 21 518 2.2E-16 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_13070 a534ccd1dcf2114a5edddcbcff2bb893 540 Gene3D G3DSA:1.10.275.30 196 305 1.1E-61 T 23-10-2018 STK_13070 a534ccd1dcf2114a5edddcbcff2bb893 540 Gene3D G3DSA:3.40.50.300 348 540 2.0E-64 T 23-10-2018 STK_13070 a534ccd1dcf2114a5edddcbcff2bb893 540 SMART SM00488 8 223 0.0063 T 23-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 STK_13070 a534ccd1dcf2114a5edddcbcff2bb893 540 Pfam PF06733 DEAD_2 48 189 2.2E-13 T 23-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 STK_13070 a534ccd1dcf2114a5edddcbcff2bb893 540 Gene3D G3DSA:3.40.50.300 1 89 2.1E-29 T 23-10-2018 STK_13070 a534ccd1dcf2114a5edddcbcff2bb893 540 SMART SM00491 394 524 3.6E-28 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 STK_13070 a534ccd1dcf2114a5edddcbcff2bb893 540 Pfam PF13307 Helicase C-terminal domain 378 524 1.9E-24 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 STK_13070 a534ccd1dcf2114a5edddcbcff2bb893 540 SMART SM00487 4 227 5.2E-6 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain STK_12310 6ac00f3067b93efc7bc49321fa1ab452 345 SUPERFAMILY SSF52418 73 321 1.7E-78 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 STK_12310 6ac00f3067b93efc7bc49321fa1ab452 345 Pfam PF02885 Glycosyl transferase family, helical bundle domain 5 66 9.1E-17 T 23-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 STK_12310 6ac00f3067b93efc7bc49321fa1ab452 345 Gene3D G3DSA:1.20.970.10 7 181 4.9E-117 T 23-10-2018 STK_12310 6ac00f3067b93efc7bc49321fa1ab452 345 Pfam PF00591 Glycosyl transferase family, a/b domain 74 320 9.4E-77 T 23-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 STK_12310 6ac00f3067b93efc7bc49321fa1ab452 345 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 7 321 3.8E-105 T 23-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 STK_12310 6ac00f3067b93efc7bc49321fa1ab452 345 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 5 343 34.233 T 23-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 STK_12310 6ac00f3067b93efc7bc49321fa1ab452 345 Gene3D G3DSA:3.40.1030.10 72 315 4.9E-117 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 STK_12310 6ac00f3067b93efc7bc49321fa1ab452 345 SUPERFAMILY SSF47648 1 69 5.1E-17 T 23-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 STK_11060 c480b499d4ac256d8d834af83dfdaeb3 367 SUPERFAMILY SSF52540 4 246 4.91E-79 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_11060 c480b499d4ac256d8d834af83dfdaeb3 367 Gene3D G3DSA:3.40.50.300 1 242 3.4E-73 T 23-10-2018 STK_11060 c480b499d4ac256d8d834af83dfdaeb3 367 Gene3D G3DSA:2.40.50.100 243 354 6.8E-29 T 23-10-2018 STK_11060 c480b499d4ac256d8d834af83dfdaeb3 367 SMART SM00382 32 230 1.1E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_11060 c480b499d4ac256d8d834af83dfdaeb3 367 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 STK_11060 c480b499d4ac256d8d834af83dfdaeb3 367 Pfam PF00005 ABC transporter 23 165 4.4E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_11060 c480b499d4ac256d8d834af83dfdaeb3 367 SUPERFAMILY SSF50331 241 357 9.23E-25 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal STK_11060 c480b499d4ac256d8d834af83dfdaeb3 367 Gene3D G3DSA:2.40.50.140 283 341 6.8E-29 T 23-10-2018 STK_11060 c480b499d4ac256d8d834af83dfdaeb3 367 Pfam PF08402 TOBE domain 280 348 6.8E-10 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 STK_18890 8f127f0043624b3983046221df96a226 109 SUPERFAMILY SSF46785 4 94 3.95E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_18890 8f127f0043624b3983046221df96a226 109 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 16 85 2.5E-9 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal STK_18890 8f127f0043624b3983046221df96a226 109 Gene3D G3DSA:1.10.10.10 1 109 2.3E-47 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_07550 c4ff49b8e0bfcd1f7e9fb9a17ed6ca25 268 Pfam PF01061 ABC-2 type transporter 20 221 1.7E-10 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 STK_04450 0198de39170165f324218b0354f21890 233 Gene3D G3DSA:1.10.10.900 87 161 1.5E-29 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily STK_04450 0198de39170165f324218b0354f21890 233 TIGRFAM TIGR00291 RNA_SBDS: rRNA metabolism protein, SBDS family 2 230 9.5E-76 T 23-10-2018 IPR002140 Ribosome maturation protein Sdo1/SBDS GO:0042256 STK_04450 0198de39170165f324218b0354f21890 233 SUPERFAMILY SSF89895 4 86 8.5E-25 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily STK_04450 0198de39170165f324218b0354f21890 233 Gene3D G3DSA:3.30.70.240 163 233 1.5E-23 T 23-10-2018 STK_04450 0198de39170165f324218b0354f21890 233 Gene3D G3DSA:3.30.1250.10 7 86 6.6E-30 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily STK_04450 0198de39170165f324218b0354f21890 233 SUPERFAMILY SSF109728 82 154 2.35E-25 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily STK_04450 0198de39170165f324218b0354f21890 233 SUPERFAMILY SSF54980 156 228 7.91E-19 T 23-10-2018 IPR035647 EF-G domain III/V-like STK_04450 0198de39170165f324218b0354f21890 233 Pfam PF09377 SBDS protein C-terminal domain 100 216 1.3E-21 T 23-10-2018 IPR018978 Ribosome maturation protein SBDS, C-terminal GO:0042254 STK_04450 0198de39170165f324218b0354f21890 233 Pfam PF01172 Shwachman-Bodian-Diamond syndrome (SBDS) protein 7 93 3.3E-26 T 23-10-2018 IPR019783 Ribosome maturation protein SBDS, N-terminal STK_12010 d4c050784b705534e8bf7ddaed356f54 245 SUPERFAMILY SSF52540 3 230 1.42E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_12010 d4c050784b705534e8bf7ddaed356f54 245 SMART SM00382 28 222 6.4E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_12010 d4c050784b705534e8bf7ddaed356f54 245 Gene3D G3DSA:3.40.50.300 1 240 4.2E-57 T 23-10-2018 STK_12010 d4c050784b705534e8bf7ddaed356f54 245 Pfam PF00005 ABC transporter 19 171 1.8E-23 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_12010 d4c050784b705534e8bf7ddaed356f54 245 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 241 9.4E-89 T 23-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 STK_05060 c001daee2d40a67a0e77403be0bdce89 374 PIRSF PIRSF001434 2 374 1.4E-134 T 23-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 STK_05060 c001daee2d40a67a0e77403be0bdce89 374 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 12 370 1.6E-123 T 23-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 STK_05060 c001daee2d40a67a0e77403be0bdce89 374 Gene3D G3DSA:3.90.1150.10 238 373 6.2E-49 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 STK_05060 c001daee2d40a67a0e77403be0bdce89 374 SUPERFAMILY SSF53383 24 371 3.94E-96 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase STK_05060 c001daee2d40a67a0e77403be0bdce89 374 Gene3D G3DSA:3.40.640.10 4 237 8.7E-69 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 STK_18460 c0b7f4a2d261ab84fead5df9f246db71 271 Gene3D G3DSA:2.120.10.30 1 269 3.7E-89 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like STK_18460 c0b7f4a2d261ab84fead5df9f246db71 271 SUPERFAMILY SSF63829 9 267 1.83E-56 T 23-10-2018 STK_18460 c0b7f4a2d261ab84fead5df9f246db71 271 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 13 246 3.1E-76 T 23-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region STK_18460 c0b7f4a2d261ab84fead5df9f246db71 271 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 186 203 2.4E-40 T 23-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) STK_18460 c0b7f4a2d261ab84fead5df9f246db71 271 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 82 103 2.4E-40 T 23-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) STK_18460 c0b7f4a2d261ab84fead5df9f246db71 271 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 227 245 2.4E-40 T 23-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) STK_18460 c0b7f4a2d261ab84fead5df9f246db71 271 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 123 145 2.4E-40 T 23-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) STK_18460 c0b7f4a2d261ab84fead5df9f246db71 271 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 146 166 2.4E-40 T 23-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) STK_06730 efd9468d595998279e3d499955a22439 126 Pfam PF03061 Thioesterase superfamily 32 102 1.5E-5 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 STK_06730 efd9468d595998279e3d499955a22439 126 Gene3D G3DSA:3.10.129.10 2 126 7.0E-46 T 23-10-2018 STK_06730 efd9468d595998279e3d499955a22439 126 SUPERFAMILY SSF54637 3 126 8.21E-44 T 23-10-2018 IPR029069 HotDog domain superfamily STK_06730 efd9468d595998279e3d499955a22439 126 PIRSF PIRSF014972 2 126 1.8E-43 T 23-10-2018 IPR025540 Fluoroacetyl-CoA thioesterase STK_24000 9f956de92ba342597a4b0e3a3ab989ad 391 SUPERFAMILY SSF103473 4 388 8.24E-38 T 23-10-2018 IPR036259 MFS transporter superfamily STK_24000 9f956de92ba342597a4b0e3a3ab989ad 391 Gene3D G3DSA:1.20.1250.20 213 390 6.9E-9 T 23-10-2018 STK_24000 9f956de92ba342597a4b0e3a3ab989ad 391 Gene3D G3DSA:1.20.1250.20 2 212 1.7E-21 T 23-10-2018 STK_24000 9f956de92ba342597a4b0e3a3ab989ad 391 Pfam PF07690 Major Facilitator Superfamily 218 382 7.3E-9 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_24000 9f956de92ba342597a4b0e3a3ab989ad 391 Pfam PF07690 Major Facilitator Superfamily 19 205 1.4E-14 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_04170 dc8d1103af557287124c0b3171dd6c1a 131 SUPERFAMILY SSF52042 4 130 6.8E-40 T 23-10-2018 IPR036351 Ribosomal protein L32e superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04170 dc8d1103af557287124c0b3171dd6c1a 131 ProDom PD003823 RIBOSOMAL L32 RIBONUCLEOPROTEIN 60S L32E 50S L32 STRAIN CHROMOSOME DIRECT 24 130 1.0E-48 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04170 dc8d1103af557287124c0b3171dd6c1a 131 ProSitePatterns PS00580 Ribosomal protein L32e signature. 24 46 - T 23-10-2018 IPR018263 Ribosomal protein L32e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04170 dc8d1103af557287124c0b3171dd6c1a 131 Pfam PF01655 Ribosomal protein L32 23 130 1.7E-33 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04170 dc8d1103af557287124c0b3171dd6c1a 131 Hamap MF_00810 50S ribosomal protein L32e [rpl32e]. 2 131 27.715 T 23-10-2018 IPR023654 Ribosomal protein L32e, archaeal GO:0003735|GO:0005840|GO:0006412 STK_04170 dc8d1103af557287124c0b3171dd6c1a 131 SMART SM01393 21 130 5.0E-49 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_16580 64d2e8891fec3dc9dfb43da4b81d2652 890 SUPERFAMILY SSF63825 348 516 1.46E-10 T 23-10-2018 STK_16580 64d2e8891fec3dc9dfb43da4b81d2652 890 SUPERFAMILY SSF101898 143 369 1.54E-23 T 23-10-2018 STK_16580 64d2e8891fec3dc9dfb43da4b81d2652 890 Gene3D G3DSA:2.130.10.10 311 489 4.5E-13 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 STK_16580 64d2e8891fec3dc9dfb43da4b81d2652 890 Gene3D G3DSA:2.130.10.10 40 309 2.9E-9 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 STK_08140 b9fc65dfdf00e2d672fbcab3359daf71 608 Pfam PF06202 Amylo-alpha-1,6-glucosidase 253 600 2.1E-126 T 23-10-2018 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 STK_08140 b9fc65dfdf00e2d672fbcab3359daf71 608 Gene3D G3DSA:1.50.10.10 254 606 4.5E-29 T 23-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 STK_08140 b9fc65dfdf00e2d672fbcab3359daf71 608 SUPERFAMILY SSF48208 172 604 1.51E-75 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 STK_08140 b9fc65dfdf00e2d672fbcab3359daf71 608 Pfam PF12439 Glycogen debranching enzyme N terminal 10 213 2.2E-54 T 23-10-2018 IPR024742 Glycogen debranching enzyme, bacterial and archaeal type, N-terminal STK_08140 b9fc65dfdf00e2d672fbcab3359daf71 608 TIGRFAM TIGR01561 gde_arch: putative glycogen debranching enzyme, archaeal type 11 543 5.4E-189 T 23-10-2018 IPR006451 Glycogen debranching enzyme, archaeal type STK_20950 77e36fbe4eff7a99264931b12e1cf805 474 Gene3D G3DSA:3.30.300.30 374 473 5.8E-15 T 23-10-2018 STK_20950 77e36fbe4eff7a99264931b12e1cf805 474 SUPERFAMILY SSF56801 78 415 6.8E-21 T 23-10-2018 STK_20950 77e36fbe4eff7a99264931b12e1cf805 474 Gene3D G3DSA:3.40.50.12780 26 371 2.1E-62 T 23-10-2018 STK_20950 77e36fbe4eff7a99264931b12e1cf805 474 Pfam PF14535 AMP-binding enzyme C-terminal domain 379 471 1.0E-16 T 23-10-2018 IPR028154 AMP-dependent ligase, C-terminal STK_05320 14c7d85d86db88a04544e0e195d2d7d1 266 Pfam PF02006 Phosphopantothenate/pantothenate synthetase 78 255 4.2E-79 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase STK_05320 14c7d85d86db88a04544e0e195d2d7d1 266 Gene3D G3DSA:3.40.50.12640 13 266 7.9E-108 T 23-10-2018 IPR038138 Phosphopantoate/pantothenate synthetase superfamily STK_05320 14c7d85d86db88a04544e0e195d2d7d1 266 PIRSF PIRSF004853 13 266 1.7E-133 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase STK_05320 14c7d85d86db88a04544e0e195d2d7d1 266 ProDom PD016827 ARCHAEA ST0532 APE1937 VNG0250C MM2281 PAE3406 AF0927 UNCHARACTERIZED C3_0043 MJ0209 78 266 5.0E-102 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase STK_12410 67b8bfa8e0b9af669256b1ed3e2ba106 447 Gene3D G3DSA:3.40.1160.10 1 290 3.3E-69 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily STK_12410 67b8bfa8e0b9af669256b1ed3e2ba106 447 SUPERFAMILY SSF55021 296 388 2.29E-11 T 23-10-2018 STK_12410 67b8bfa8e0b9af669256b1ed3e2ba106 447 SUPERFAMILY SSF53633 1 286 2.49E-57 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily STK_12410 67b8bfa8e0b9af669256b1ed3e2ba106 447 Pfam PF00696 Amino acid kinase family 2 277 8.8E-39 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 STK_12410 67b8bfa8e0b9af669256b1ed3e2ba106 447 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 441 4.0E-81 T 23-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 STK_12410 67b8bfa8e0b9af669256b1ed3e2ba106 447 PIRSF PIRSF000726 1 447 6.2E-73 T 23-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 STK_12410 67b8bfa8e0b9af669256b1ed3e2ba106 447 Gene3D G3DSA:3.30.70.260 370 446 7.5E-6 T 23-10-2018 STK_12410 67b8bfa8e0b9af669256b1ed3e2ba106 447 Gene3D G3DSA:3.30.70.260 292 369 1.7E-9 T 23-10-2018 STK_18580 83ae549ed14042562949e7b524fa8ebb 530 Pfam PF13520 Amino acid permease 21 497 6.8E-32 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_18580 83ae549ed14042562949e7b524fa8ebb 530 Gene3D G3DSA:1.20.1740.10 17 516 2.5E-10 T 23-10-2018 STK_18580 83ae549ed14042562949e7b524fa8ebb 530 PIRSF PIRSF006060 2 527 5.5E-25 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_21250 b615a5673a9ef936764178eb4f8804e2 169 SUPERFAMILY SSF52972 1 166 4.14E-47 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like STK_21250 b615a5673a9ef936764178eb4f8804e2 169 Pfam PF01931 Protein of unknown function DUF84 6 164 2.5E-50 T 23-10-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 STK_21250 b615a5673a9ef936764178eb4f8804e2 169 Hamap MF_00648 Non-canonical purine NTP phosphatase. 1 169 29.286 T 23-10-2018 IPR002786 Non-canonical purine NTP phosphatase STK_21250 b615a5673a9ef936764178eb4f8804e2 169 TIGRFAM TIGR00258 TIGR00258: inosine/xanthosine triphosphatase 5 167 4.9E-36 T 23-10-2018 IPR002786 Non-canonical purine NTP phosphatase STK_21250 b615a5673a9ef936764178eb4f8804e2 169 Gene3D G3DSA:3.90.950.10 1 168 4.4E-49 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like STK_09510 35b4fdcdccecb2010d7012b7c7e976f0 195 Gene3D G3DSA:3.90.1140.10 2 181 3.3E-49 T 23-10-2018 STK_09510 35b4fdcdccecb2010d7012b7c7e976f0 195 SUPERFAMILY SSF55144 2 180 9.07E-40 T 23-10-2018 IPR009097 Cyclic phosphodiesterase STK_09510 35b4fdcdccecb2010d7012b7c7e976f0 195 Pfam PF02834 LigT like Phosphoesterase 95 174 2.2E-12 T 23-10-2018 IPR014051 Phosphoesterase, HXTX STK_09510 35b4fdcdccecb2010d7012b7c7e976f0 195 Pfam PF02834 LigT like Phosphoesterase 17 88 6.6E-16 T 23-10-2018 IPR014051 Phosphoesterase, HXTX STK_09510 35b4fdcdccecb2010d7012b7c7e976f0 195 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 2 182 25.534 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 STK_09510 35b4fdcdccecb2010d7012b7c7e976f0 195 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 2 179 2.2E-44 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 STK_00850 77304502d2dbc437741ae2a044547210 266 SUPERFAMILY SSF47203 144 256 2.09E-21 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 STK_00850 77304502d2dbc437741ae2a044547210 266 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 155 207 4.4E-8 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 STK_00850 77304502d2dbc437741ae2a044547210 266 Gene3D G3DSA:1.20.140.10 147 212 3.2E-11 T 23-10-2018 STK_23720 f875947f7848fd580dbed94b97c9be62 250 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 188 204 2.9E-6 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_23720 f875947f7848fd580dbed94b97c9be62 250 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 214 233 2.9E-6 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_23720 f875947f7848fd580dbed94b97c9be62 250 Gene3D G3DSA:1.10.10.10 188 250 5.9E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_23720 f875947f7848fd580dbed94b97c9be62 250 SUPERFAMILY SSF46785 172 244 2.73E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_23720 f875947f7848fd580dbed94b97c9be62 250 Pfam PF13412 Winged helix-turn-helix DNA-binding 188 234 7.9E-8 T 23-10-2018 STK_21980 69a582c8aed14742ab540263e06c91e8 712 SUPERFAMILY SSF51395 423 697 6.45E-24 T 23-10-2018 STK_21980 69a582c8aed14742ab540263e06c91e8 712 Gene3D G3DSA:3.20.20.70 419 702 6.5E-11 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_21980 69a582c8aed14742ab540263e06c91e8 712 Pfam PF04898 Glutamate synthase central domain 425 484 1.0E-6 T 23-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 STK_21980 69a582c8aed14742ab540263e06c91e8 712 Gene3D G3DSA:3.20.20.70 21 403 1.2E-104 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_21980 69a582c8aed14742ab540263e06c91e8 712 Pfam PF01645 Conserved region in glutamate synthase 76 377 1.1E-93 T 23-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 STK_21980 69a582c8aed14742ab540263e06c91e8 712 SUPERFAMILY SSF51395 40 394 2.14E-96 T 23-10-2018 STK_08260 1e2ef70271c906d4d7f23941af0e700f 127 Gene3D G3DSA:3.10.580.10 1 126 2.2E-33 T 23-10-2018 STK_08260 1e2ef70271c906d4d7f23941af0e700f 127 Pfam PF00571 CBS domain 75 123 2.3E-10 T 23-10-2018 IPR000644 CBS domain STK_08260 1e2ef70271c906d4d7f23941af0e700f 127 Pfam PF00571 CBS domain 4 57 4.1E-11 T 23-10-2018 IPR000644 CBS domain STK_08260 1e2ef70271c906d4d7f23941af0e700f 127 SUPERFAMILY SSF54631 4 124 8.72E-31 T 23-10-2018 STK_08260 1e2ef70271c906d4d7f23941af0e700f 127 SMART SM00116 11 58 4.8E-8 T 23-10-2018 IPR000644 CBS domain STK_08260 1e2ef70271c906d4d7f23941af0e700f 127 SMART SM00116 75 123 1.5E-11 T 23-10-2018 IPR000644 CBS domain STK_00410 9134528b45ceb98ae25a8c4c7021e5b1 347 Gene3D G3DSA:3.30.420.140 147 258 9.2E-6 T 23-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 STK_00410 9134528b45ceb98ae25a8c4c7021e5b1 347 Pfam PF01385 Probable transposase 82 197 1.7E-36 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 STK_00410 9134528b45ceb98ae25a8c4c7021e5b1 347 Pfam PF07282 Putative transposase DNA-binding domain 212 280 2.0E-19 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_00410 9134528b45ceb98ae25a8c4c7021e5b1 347 SUPERFAMILY SSF53098 169 243 1.9E-5 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily STK_26340 7b5fbf84b8c48bf3e2cacf3d8a46761a 304 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 289 22.222 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 STK_26340 7b5fbf84b8c48bf3e2cacf3d8a46761a 304 Gene3D G3DSA:3.100.10.20 2 80 1.5E-22 T 23-10-2018 STK_26340 7b5fbf84b8c48bf3e2cacf3d8a46761a 304 Gene3D G3DSA:1.20.120.920 84 304 2.7E-43 T 23-10-2018 STK_26340 7b5fbf84b8c48bf3e2cacf3d8a46761a 304 Pfam PF01867 CRISPR associated protein Cas1 6 120 6.4E-22 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 STK_26340 7b5fbf84b8c48bf3e2cacf3d8a46761a 304 Pfam PF01867 CRISPR associated protein Cas1 143 257 3.8E-28 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 STK_26340 7b5fbf84b8c48bf3e2cacf3d8a46761a 304 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 4 298 9.2E-83 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 STK_04840 20189d45c5d5a1329916690c4a5a40c5 209 Gene3D G3DSA:3.40.50.2020 4 181 1.9E-41 T 23-10-2018 STK_04840 20189d45c5d5a1329916690c4a5a40c5 209 Pfam PF00156 Phosphoribosyl transferase domain 19 149 9.8E-19 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 STK_04840 20189d45c5d5a1329916690c4a5a40c5 209 SUPERFAMILY SSF53271 8 162 8.65E-37 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like STK_19500 e9c3c25aeb14328601c28bf20f7e6ca9 126 SUPERFAMILY SSF46785 23 82 1.09E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_19500 e9c3c25aeb14328601c28bf20f7e6ca9 126 Pfam PF04693 Archaeal putative transposase ISC1217 1 119 8.2E-58 T 23-10-2018 IPR006783 Transposase, ISC1217 STK_05020 8bd071dc7cf5f9be842a94dc216c83c4 383 Gene3D G3DSA:3.40.50.300 2 208 1.3E-46 T 23-10-2018 STK_05020 8bd071dc7cf5f9be842a94dc216c83c4 383 SMART SM00382 38 175 2.5E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_05020 8bd071dc7cf5f9be842a94dc216c83c4 383 Pfam PF07728 AAA domain (dynein-related subfamily) 41 168 3.3E-28 T 23-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 STK_05020 8bd071dc7cf5f9be842a94dc216c83c4 383 SUPERFAMILY SSF52540 9 193 3.61E-25 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_25830 6f385cb7211173d09a731493738097b2 175 Pfam PF01909 Nucleotidyltransferase domain 28 106 2.6E-9 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_25830 6f385cb7211173d09a731493738097b2 175 Gene3D G3DSA:3.30.460.10 10 141 1.5E-31 T 23-10-2018 STK_25830 6f385cb7211173d09a731493738097b2 175 SUPERFAMILY SSF81301 9 139 3.74E-23 T 23-10-2018 STK_24390 8a885c0cdbdc2a1b06355248e207ef6a 247 SUPERFAMILY SSF52540 20 224 3.47E-15 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_24390 8a885c0cdbdc2a1b06355248e207ef6a 247 Gene3D G3DSA:3.40.50.300 20 236 3.3E-14 T 23-10-2018 STK_24390 8a885c0cdbdc2a1b06355248e207ef6a 247 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 22 224 1.4E-7 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain STK_08660 72b84856774a23e349f43cddb7d3c971 344 Pfam PF05913 Bacterial protein of unknown function (DUF871) 13 338 6.9E-80 T 23-10-2018 IPR008589 Protein of unknown function DUF871, prokaryotic STK_08660 72b84856774a23e349f43cddb7d3c971 344 SUPERFAMILY SSF51445 8 230 3.44E-56 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily STK_08660 72b84856774a23e349f43cddb7d3c971 344 Gene3D G3DSA:2.40.100.10 231 339 9.5E-9 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily STK_08660 72b84856774a23e349f43cddb7d3c971 344 Gene3D G3DSA:3.20.20.70 2 229 1.3E-52 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_08660 72b84856774a23e349f43cddb7d3c971 344 SUPERFAMILY SSF50891 233 339 1.21E-18 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily STK_21670 408b2c956df88b0bb695514d19caf03f 1082 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 433 443 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site STK_21670 408b2c956df88b0bb695514d19caf03f 1082 Pfam PF09286 Pro-kumamolisin, activation domain 27 113 6.5E-6 T 23-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 STK_21670 408b2c956df88b0bb695514d19caf03f 1082 SUPERFAMILY SSF52743 172 507 5.89E-67 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 STK_21670 408b2c956df88b0bb695514d19caf03f 1082 Gene3D G3DSA:3.40.50.200 159 511 6.1E-79 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 STK_21670 408b2c956df88b0bb695514d19caf03f 1082 PIRSF PIRSF032623 1 1082 0.0 T 23-10-2018 IPR017001 Peptidase S53, physarolisin II, archaeal-type STK_21670 408b2c956df88b0bb695514d19caf03f 1082 SMART SM00944 22 145 5.3E-21 T 23-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 STK_21670 408b2c956df88b0bb695514d19caf03f 1082 SUPERFAMILY SSF48726 722 799 4.43E-6 T 23-10-2018 IPR036179 Immunoglobulin-like domain superfamily STK_00120 0c7f5478afe72ca5337f97ce67d22555 888 Pfam PF01966 HD domain 190 268 7.1E-8 T 23-10-2018 IPR006674 HD domain STK_00120 0c7f5478afe72ca5337f97ce67d22555 888 Gene3D G3DSA:1.10.3210.10 170 311 4.5E-6 T 23-10-2018 STK_00120 0c7f5478afe72ca5337f97ce67d22555 888 SUPERFAMILY SSF109604 160 318 5.16E-10 T 23-10-2018 STK_02804 162036a12e2608f832cdc5b8965c6754 61 SUPERFAMILY SSF57716 6 57 9.27E-17 T 23-10-2018 STK_02804 162036a12e2608f832cdc5b8965c6754 61 Pfam PF01246 Ribosomal protein L24e 4 57 2.4E-21 T 23-10-2018 IPR000988 Ribosomal protein L24e-related STK_02804 162036a12e2608f832cdc5b8965c6754 61 SMART SM00746 7 45 2.0E-12 T 23-10-2018 IPR011017 TRASH domain STK_02804 162036a12e2608f832cdc5b8965c6754 61 Hamap MF_00773 50S ribosomal protein L24e [rpl24e]. 2 56 27.371 T 23-10-2018 IPR023438 Ribosomal protein L24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_02804 162036a12e2608f832cdc5b8965c6754 61 ProSitePatterns PS01073 Ribosomal protein L24e signature. 9 26 - T 23-10-2018 IPR023442 Ribosomal protein L24e, conserved site STK_02804 162036a12e2608f832cdc5b8965c6754 61 Gene3D G3DSA:2.30.170.20 2 61 3.8E-27 T 23-10-2018 IPR038630 Ribosomal protein L24e/L24 superfamily STK_24130 f0c6ce474199adf576ca3c99b4b3a841 278 Gene3D G3DSA:3.40.50.720 2 186 3.6E-63 T 23-10-2018 STK_24130 f0c6ce474199adf576ca3c99b4b3a841 278 Gene3D G3DSA:1.10.1040.10 187 278 5.1E-23 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 STK_24130 f0c6ce474199adf576ca3c99b4b3a841 278 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 182 6.1E-64 T 23-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 STK_24130 f0c6ce474199adf576ca3c99b4b3a841 278 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 185 276 1.5E-23 T 23-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 STK_24130 f0c6ce474199adf576ca3c99b4b3a841 278 SUPERFAMILY SSF51735 5 181 2.92E-55 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_24130 f0c6ce474199adf576ca3c99b4b3a841 278 PIRSF PIRSF000105 2 278 4.2E-82 T 23-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 STK_24130 f0c6ce474199adf576ca3c99b4b3a841 278 SUPERFAMILY SSF48179 185 276 2.89E-19 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 STK_23760 322ffe94cb845ddaaddb23492ec7111b 285 Pfam PF01925 Sulfite exporter TauE/SafE 11 276 1.4E-43 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 STK_10930 6fd151cf4a6c8834753b2da4114a666b 160 Pfam PF05942 Archaeal PaREP1/PaREP8 family 43 145 1.2E-23 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_10930 6fd151cf4a6c8834753b2da4114a666b 160 Gene3D G3DSA:1.20.120.330 42 159 1.9E-15 T 23-10-2018 STK_17450 33d7fcb2f6de2e75c992299c269c2b38 565 Pfam PF00326 Prolyl oligopeptidase family 369 565 1.4E-42 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 STK_17450 33d7fcb2f6de2e75c992299c269c2b38 565 Gene3D G3DSA:3.40.50.1820 319 563 5.8E-60 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold STK_17450 33d7fcb2f6de2e75c992299c269c2b38 565 SUPERFAMILY SSF53474 319 564 2.16E-51 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold STK_17450 33d7fcb2f6de2e75c992299c269c2b38 565 Gene3D G3DSA:2.130.10.150 17 309 9.8E-114 T 23-10-2018 STK_17450 33d7fcb2f6de2e75c992299c269c2b38 565 SUPERFAMILY SSF50993 3 309 1.65E-138 T 23-10-2018 STK_20550 01d423f6b39302d9a6864acfe72dd291 208 Gene3D G3DSA:1.10.150.240 15 80 1.2E-33 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 STK_20550 01d423f6b39302d9a6864acfe72dd291 208 Gene3D G3DSA:3.40.50.1000 3 175 1.2E-33 T 23-10-2018 IPR023214 HAD superfamily STK_20550 01d423f6b39302d9a6864acfe72dd291 208 SUPERFAMILY SSF56784 1 205 1.18E-38 T 23-10-2018 IPR036412 HAD-like superfamily STK_20550 01d423f6b39302d9a6864acfe72dd291 208 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 94 169 7.1E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 STK_20550 01d423f6b39302d9a6864acfe72dd291 208 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 171 1.4E-27 T 23-10-2018 STK_20650 9ac59f9c69d0fea785d7defc0d7f073a 146 SUPERFAMILY SSF52161 2 144 1.11E-36 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 STK_20650 9ac59f9c69d0fea785d7defc0d7f073a 146 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 5 135 19.056 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 STK_20650 9ac59f9c69d0fea785d7defc0d7f073a 146 ProSitePatterns PS00783 Ribosomal protein L13 signature. 84 106 - T 23-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 STK_20650 9ac59f9c69d0fea785d7defc0d7f073a 146 TIGRFAM TIGR01077 L13_A_E: ribosomal protein uL13 6 142 8.4E-41 T 23-10-2018 IPR005755 Ribosomal protein L13, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 STK_20650 9ac59f9c69d0fea785d7defc0d7f073a 146 Gene3D G3DSA:3.90.1180.10 5 144 1.9E-43 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 STK_20650 9ac59f9c69d0fea785d7defc0d7f073a 146 PIRSF PIRSF002181 1 146 1.5E-36 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 STK_20650 9ac59f9c69d0fea785d7defc0d7f073a 146 Pfam PF00572 Ribosomal protein L13 6 112 2.8E-11 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 STK_16290 2b6ea371c69b43edc1ee0396d5a4bdad 246 Pfam PF00753 Metallo-beta-lactamase superfamily 22 183 3.9E-14 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_16290 2b6ea371c69b43edc1ee0396d5a4bdad 246 Gene3D G3DSA:3.60.15.10 1 246 8.6E-69 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_16290 2b6ea371c69b43edc1ee0396d5a4bdad 246 SMART SM00849 12 183 9.8E-34 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_16290 2b6ea371c69b43edc1ee0396d5a4bdad 246 SUPERFAMILY SSF56281 1 217 1.08E-47 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_12960 03a7747620398ef305543e1247d7cf13 131 SUPERFAMILY SSF50249 69 130 6.0E-14 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_12960 03a7747620398ef305543e1247d7cf13 131 Pfam PF01287 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 70 131 1.6E-8 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 STK_12960 03a7747620398ef305543e1247d7cf13 131 TIGRFAM TIGR00037 eIF_5A: translation elongation factor IF5A 5 131 2.2E-44 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 STK_12960 03a7747620398ef305543e1247d7cf13 131 Gene3D G3DSA:2.40.50.140 69 131 4.1E-27 T 23-10-2018 STK_12960 03a7747620398ef305543e1247d7cf13 131 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 8 38 4.7E-6 T 23-10-2018 IPR013185 Translation elongation factor, KOW-like STK_12960 03a7747620398ef305543e1247d7cf13 131 Gene3D G3DSA:2.30.30.30 1 68 1.1E-30 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 STK_12960 03a7747620398ef305543e1247d7cf13 131 ProSitePatterns PS00302 Eukaryotic initiation factor 5A hypusine signature. 34 41 - T 23-10-2018 IPR019769 Translation elongation factor, IF5A, hypusine site GO:0003723|GO:0003746|GO:0043022|GO:0045901|GO:0045905 STK_12960 03a7747620398ef305543e1247d7cf13 131 SUPERFAMILY SSF50104 2 77 1.0E-23 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily STK_12960 03a7747620398ef305543e1247d7cf13 131 SMART SM01376 69 131 9.9E-20 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 STK_12960 03a7747620398ef305543e1247d7cf13 131 PIRSF PIRSF003025 1 131 7.7E-50 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 STK_12960 03a7747620398ef305543e1247d7cf13 131 Hamap MF_00085 Translation initiation factor 5A [eif5a]. 2 130 34.654 T 23-10-2018 IPR022847 Translation elongation factor IF5A, archaeal STK_15580 d559ce03fdeae1a113ffd62aa45b52e3 120 Pfam PF14947 Winged helix-turn-helix 9 84 1.1E-23 T 23-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain STK_15580 d559ce03fdeae1a113ffd62aa45b52e3 120 SUPERFAMILY SSF46785 10 94 4.22E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_15580 d559ce03fdeae1a113ffd62aa45b52e3 120 Gene3D G3DSA:1.10.10.10 7 104 6.6E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_25450 c012d7baa6847159947a0054d4685046 581 Pfam PF01380 SIS domain 274 396 1.0E-21 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 STK_25450 c012d7baa6847159947a0054d4685046 581 Pfam PF01380 SIS domain 444 531 1.5E-10 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 STK_25450 c012d7baa6847159947a0054d4685046 581 SUPERFAMILY SSF56235 3 220 1.12E-43 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_25450 c012d7baa6847159947a0054d4685046 581 Gene3D G3DSA:3.40.50.10490 426 567 1.0E-88 T 23-10-2018 STK_25450 c012d7baa6847159947a0054d4685046 581 Pfam PF13522 Glutamine amidotransferase domain 62 184 1.4E-14 T 23-10-2018 STK_25450 c012d7baa6847159947a0054d4685046 581 Gene3D G3DSA:3.60.20.10 3 231 1.5E-45 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_25450 c012d7baa6847159947a0054d4685046 581 SUPERFAMILY SSF53697 242 580 1.95E-73 T 23-10-2018 STK_25450 c012d7baa6847159947a0054d4685046 581 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 3 581 5.7E-130 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 STK_25450 c012d7baa6847159947a0054d4685046 581 Gene3D G3DSA:3.40.50.10490 238 581 1.0E-88 T 23-10-2018 STK_13710 778ed2452f34b7cefcb38715abdf9c6e 151 SUPERFAMILY SSF46579 13 143 6.54E-18 T 23-10-2018 STK_13710 778ed2452f34b7cefcb38715abdf9c6e 151 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 14 142 7.1E-19 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 STK_13710 778ed2452f34b7cefcb38715abdf9c6e 151 Gene3D G3DSA:1.10.287.370 1 150 7.9E-12 T 23-10-2018 IPR009053 Prefoldin STK_13710 778ed2452f34b7cefcb38715abdf9c6e 151 Pfam PF02996 Prefoldin subunit 24 142 4.3E-27 T 23-10-2018 IPR004127 Prefoldin alpha-like STK_13710 778ed2452f34b7cefcb38715abdf9c6e 151 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 5 142 13.821 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 STK_14480 20545913383ea206632a9295c7fe3562 162 Gene3D G3DSA:3.40.50.1000 1 159 1.0E-20 T 23-10-2018 IPR023214 HAD superfamily STK_14480 20545913383ea206632a9295c7fe3562 162 SUPERFAMILY SSF56784 1 127 1.09E-17 T 23-10-2018 IPR036412 HAD-like superfamily STK_14480 20545913383ea206632a9295c7fe3562 162 Pfam PF12689 Acid Phosphatase 3 84 3.9E-11 T 23-10-2018 IPR010036 Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type GO:0016791 STK_14480 20545913383ea206632a9295c7fe3562 162 TIGRFAM TIGR01685 MDP-1: magnesium-dependent phosphatase-1 1 161 4.4E-66 T 23-10-2018 IPR010036 Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type GO:0016791 STK_14480 20545913383ea206632a9295c7fe3562 162 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 3 137 5.1E-32 T 23-10-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC STK_18050 4944f13196f79ba6aa0d9694ed84ff06 378 Gene3D G3DSA:1.10.580.10 22 349 2.5E-137 T 23-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 STK_18050 4944f13196f79ba6aa0d9694ed84ff06 378 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 7 378 1.6E-139 T 23-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 STK_18050 4944f13196f79ba6aa0d9694ed84ff06 378 Gene3D G3DSA:1.10.230.10 221 324 2.5E-137 T 23-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain STK_18050 4944f13196f79ba6aa0d9694ed84ff06 378 ProSitePatterns PS00480 Citrate synthase signature. 256 268 - T 23-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 STK_18050 4944f13196f79ba6aa0d9694ed84ff06 378 PIRSF PIRSF001369 1 378 3.5E-147 T 23-10-2018 IPR024176 Citrate synthase, bacterial-type STK_18050 4944f13196f79ba6aa0d9694ed84ff06 378 Pfam PF00285 Citrate synthase, C-terminal domain 8 361 7.0E-117 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 STK_18050 4944f13196f79ba6aa0d9694ed84ff06 378 PRINTS PR00143 Citrate synthase signature 330 344 9.4E-46 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 STK_18050 4944f13196f79ba6aa0d9694ed84ff06 378 PRINTS PR00143 Citrate synthase signature 195 223 9.4E-46 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 STK_18050 4944f13196f79ba6aa0d9694ed84ff06 378 PRINTS PR00143 Citrate synthase signature 124 137 9.4E-46 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 STK_18050 4944f13196f79ba6aa0d9694ed84ff06 378 PRINTS PR00143 Citrate synthase signature 173 188 9.4E-46 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 STK_18050 4944f13196f79ba6aa0d9694ed84ff06 378 PRINTS PR00143 Citrate synthase signature 249 269 9.4E-46 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 STK_18050 4944f13196f79ba6aa0d9694ed84ff06 378 PRINTS PR00143 Citrate synthase signature 310 326 9.4E-46 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 STK_18050 4944f13196f79ba6aa0d9694ed84ff06 378 SUPERFAMILY SSF48256 5 378 8.24E-126 T 23-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 STK_25360 e6f6a9774699381deae7544e1627f2e7 322 Pfam PF00005 ABC transporter 25 183 1.3E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_25360 e6f6a9774699381deae7544e1627f2e7 322 Gene3D G3DSA:3.40.50.300 3 321 3.4E-90 T 23-10-2018 STK_25360 e6f6a9774699381deae7544e1627f2e7 322 SMART SM00382 34 240 3.2E-18 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_25360 e6f6a9774699381deae7544e1627f2e7 322 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 STK_25360 e6f6a9774699381deae7544e1627f2e7 322 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 294 6.0E-15 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 STK_25360 e6f6a9774699381deae7544e1627f2e7 322 SUPERFAMILY SSF52540 4 263 7.57E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_25360 e6f6a9774699381deae7544e1627f2e7 322 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 312 8.6E-19 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 STK_13875 1f10b2ed97faae64a2f60652732f59f9 132 Pfam PF00085 Thioredoxin 30 129 1.2E-25 T 23-10-2018 IPR013766 Thioredoxin domain GO:0045454 STK_13875 1f10b2ed97faae64a2f60652732f59f9 132 SUPERFAMILY SSF52833 19 131 4.01E-37 T 23-10-2018 IPR036249 Thioredoxin-like superfamily STK_13875 1f10b2ed97faae64a2f60652732f59f9 132 PIRSF PIRSF000077 26 131 9.8E-32 T 23-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 STK_13875 1f10b2ed97faae64a2f60652732f59f9 132 Gene3D G3DSA:3.40.30.10 24 132 8.9E-35 T 23-10-2018 STK_13875 1f10b2ed97faae64a2f60652732f59f9 132 TIGRFAM TIGR01068 thioredoxin: thioredoxin 33 130 1.6E-30 T 23-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 STK_13875 1f10b2ed97faae64a2f60652732f59f9 132 ProSitePatterns PS00194 Thioredoxin family active site. 48 66 - T 23-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 STK_01690 1367d141149b8c16328fdccc995ff48e 381 Hamap MF_00140_A Tryptophan--tRNA ligase [trpS]. 6 368 44.258 T 23-10-2018 IPR020653 Tryptophan-tRNA ligase, archaea GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 STK_01690 1367d141149b8c16328fdccc995ff48e 381 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 73 379 2.3E-86 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 STK_01690 1367d141149b8c16328fdccc995ff48e 381 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 139 158 4.9E-21 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 STK_01690 1367d141149b8c16328fdccc995ff48e 381 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 254 264 4.9E-21 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 STK_01690 1367d141149b8c16328fdccc995ff48e 381 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 210 231 4.9E-21 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 STK_01690 1367d141149b8c16328fdccc995ff48e 381 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 86 102 4.9E-21 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 STK_01690 1367d141149b8c16328fdccc995ff48e 381 Gene3D G3DSA:3.40.50.620 1 258 4.3E-104 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_01690 1367d141149b8c16328fdccc995ff48e 381 Pfam PF00579 tRNA synthetases class I (W and Y) 74 348 3.4E-25 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_01690 1367d141149b8c16328fdccc995ff48e 381 Gene3D G3DSA:1.10.240.10 259 380 7.6E-47 T 23-10-2018 STK_01690 1367d141149b8c16328fdccc995ff48e 381 SUPERFAMILY SSF52374 5 365 3.87E-93 T 23-10-2018 STK_26070 a1f1bfb3e689b617efd982d3128bd2c7 105 Pfam PF11494 Ta0938 1 104 1.8E-55 T 23-10-2018 IPR021585 Ta0938 STK_15050 0022a937638e62f5f527211511af792c 282 SUPERFAMILY SSF56059 85 277 6.72E-38 T 23-10-2018 STK_15050 0022a937638e62f5f527211511af792c 282 TIGRFAM TIGR02144 LysX_arch: lysine biosynthesis enzyme LysX 4 281 1.0E-108 T 23-10-2018 IPR011870 Lysine biosynthesis enzyme LysX GO:0003824|GO:0005524|GO:0009085 STK_15050 0022a937638e62f5f527211511af792c 282 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 4 276 2.9E-91 T 23-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 STK_15050 0022a937638e62f5f527211511af792c 282 Gene3D G3DSA:3.30.470.20 171 282 1.1E-29 T 23-10-2018 STK_15050 0022a937638e62f5f527211511af792c 282 Gene3D G3DSA:3.30.1490.20 102 170 6.1E-27 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 STK_15050 0022a937638e62f5f527211511af792c 282 SUPERFAMILY SSF52440 2 86 2.82E-22 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily STK_15050 0022a937638e62f5f527211511af792c 282 Gene3D G3DSA:3.40.50.20 1 101 2.7E-33 T 23-10-2018 STK_15050 0022a937638e62f5f527211511af792c 282 Pfam PF08443 RimK-like ATP-grasp domain 86 276 3.6E-26 T 23-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 STK_20970 191d382e4b8658cddd9b2d1c2ae2b781 312 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 9 295 2.5E-93 T 23-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 STK_20970 191d382e4b8658cddd9b2d1c2ae2b781 312 Gene3D G3DSA:3.40.50.300 36 247 1.1E-69 T 23-10-2018 STK_20970 191d382e4b8658cddd9b2d1c2ae2b781 312 SUPERFAMILY SSF52540 3 270 4.05E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_20970 191d382e4b8658cddd9b2d1c2ae2b781 312 SMART SM00382 41 262 0.005 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_20970 191d382e4b8658cddd9b2d1c2ae2b781 312 Pfam PF03308 ArgK protein 15 274 6.1E-88 T 23-10-2018 STK_09710 c94d948bffce925d1aa090380a49b6b3 390 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 289 8.9E-20 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 STK_09710 c94d948bffce925d1aa090380a49b6b3 390 Gene3D G3DSA:3.50.50.60 4 312 1.4E-71 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_09710 c94d948bffce925d1aa090380a49b6b3 390 Gene3D G3DSA:3.50.50.60 114 258 1.4E-71 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_09710 c94d948bffce925d1aa090380a49b6b3 390 SUPERFAMILY SSF51905 123 247 4.04E-26 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_09710 c94d948bffce925d1aa090380a49b6b3 390 SUPERFAMILY SSF51905 1 136 1.3E-23 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_06010 3a655dd1a3ead3de809c07161169e560 221 Gene3D G3DSA:3.40.109.10 1 177 2.5E-47 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 STK_06010 3a655dd1a3ead3de809c07161169e560 221 Pfam PF00881 Nitroreductase family 7 171 3.5E-29 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 STK_06010 3a655dd1a3ead3de809c07161169e560 221 SUPERFAMILY SSF55469 1 212 2.09E-50 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 STK_06010 3a655dd1a3ead3de809c07161169e560 221 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 3 199 1.4E-70 T 23-10-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5523 STK_04080 dd422e7d9c9ac1a85eb03a970c4bbd5a 180 TIGRFAM TIGR02173 cyt_kin_arch: putative cytidylate kinase 1 172 1.6E-73 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 STK_04080 dd422e7d9c9ac1a85eb03a970c4bbd5a 180 Hamap MF_00239 Cytidylate kinase [cmk]. 1 175 46.549 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 STK_04080 dd422e7d9c9ac1a85eb03a970c4bbd5a 180 SUPERFAMILY SSF52540 1 175 3.53E-27 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_04080 dd422e7d9c9ac1a85eb03a970c4bbd5a 180 Gene3D G3DSA:3.40.50.300 1 174 1.0E-42 T 23-10-2018 STK_04080 dd422e7d9c9ac1a85eb03a970c4bbd5a 180 Pfam PF13189 Cytidylate kinase-like family 2 156 1.3E-19 T 23-10-2018 STK_04080 dd422e7d9c9ac1a85eb03a970c4bbd5a 180 PRINTS PR01100 Shikimate kinase family signature 93 110 3.0E-5 T 23-10-2018 STK_04080 dd422e7d9c9ac1a85eb03a970c4bbd5a 180 PRINTS PR01100 Shikimate kinase family signature 3 18 3.0E-5 T 23-10-2018 STK_03000 5646dfeb7ab55b520c220d327bc43c1b 185 Gene3D G3DSA:2.40.320.10 4 178 2.4E-41 T 23-10-2018 STK_03000 5646dfeb7ab55b520c220d327bc43c1b 185 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 4 172 2.5E-40 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 STK_03000 5646dfeb7ab55b520c220d327bc43c1b 185 Pfam PF01928 CYTH domain 4 164 1.9E-31 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 STK_03000 5646dfeb7ab55b520c220d327bc43c1b 185 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 4 145 1.0E-73 T 23-10-2018 STK_03000 5646dfeb7ab55b520c220d327bc43c1b 185 SUPERFAMILY SSF55154 4 172 1.41E-37 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 STK_03000 5646dfeb7ab55b520c220d327bc43c1b 185 SMART SM01118 3 174 2.3E-20 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 STK_09760 b0e1558bfe4af80d0455f532d0cc6ddf 399 Pfam PF01966 HD domain 50 142 5.2E-10 T 23-10-2018 IPR006674 HD domain STK_09760 b0e1558bfe4af80d0455f532d0cc6ddf 399 SUPERFAMILY SSF109604 1 393 2.09E-80 T 23-10-2018 STK_09760 b0e1558bfe4af80d0455f532d0cc6ddf 399 Gene3D G3DSA:1.10.3210.10 1 298 1.8E-78 T 23-10-2018 STK_09760 b0e1558bfe4af80d0455f532d0cc6ddf 399 SMART SM00471 46 198 7.6E-10 T 23-10-2018 IPR003607 HD/PDEase domain STK_23930 6f018f165c4f19eec4a41be7fae534c8 225 Pfam PF06525 Sulfocyanin (SoxE) domain 78 224 9.9E-61 T 23-10-2018 IPR010532 Sulfocyanin GO:0005507|GO:0055114 STK_23930 6f018f165c4f19eec4a41be7fae534c8 225 SUPERFAMILY SSF49503 73 214 2.68E-22 T 23-10-2018 IPR008972 Cupredoxin STK_23930 6f018f165c4f19eec4a41be7fae534c8 225 PIRSF PIRSF022145 1 225 1.4E-87 T 23-10-2018 IPR010532 Sulfocyanin GO:0005507|GO:0055114 STK_23930 6f018f165c4f19eec4a41be7fae534c8 225 ProDom PD003655 COPPER ELECTRON AZURIN METAL-BINDING PERIPLASMIC PRECURSOR SIGNAL SEQUENCING DIRECT MEMBRANE 108 212 0.007 T 23-10-2018 STK_23930 6f018f165c4f19eec4a41be7fae534c8 225 TIGRFAM TIGR03094 sulfo_cyanin: sulfocyanin 51 224 4.6E-52 T 23-10-2018 IPR010532 Sulfocyanin GO:0005507|GO:0055114 STK_23930 6f018f165c4f19eec4a41be7fae534c8 225 Gene3D G3DSA:2.60.40.420 40 214 1.9E-22 T 23-10-2018 IPR008972 Cupredoxin STK_23930 6f018f165c4f19eec4a41be7fae534c8 225 ProSitePatterns PS00079 Multicopper oxidases signature 1. 192 212 - T 23-10-2018 IPR033138 Multicopper oxidases, conserved site STK_08685 5721a199796a8eaa67a9f1323096cc50 101 SUPERFAMILY SSF52540 1 87 6.0E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_08685 5721a199796a8eaa67a9f1323096cc50 101 Gene3D G3DSA:3.40.50.300 1 101 1.8E-12 T 23-10-2018 STK_08685 5721a199796a8eaa67a9f1323096cc50 101 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 1 87 2.4E-6 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_02790 78db9c1facf8bf8f3e003a9bd5785b8a 602 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 143 2.1E-17 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 STK_02790 78db9c1facf8bf8f3e003a9bd5785b8a 602 Pfam PF14578 Elongation factor Tu domain 4 470 555 5.2E-37 T 23-10-2018 IPR029459 Elongation factor Tu-type domain STK_02790 78db9c1facf8bf8f3e003a9bd5785b8a 602 Gene3D G3DSA:2.40.30.10 237 354 2.9E-39 T 23-10-2018 STK_02790 78db9c1facf8bf8f3e003a9bd5785b8a 602 Gene3D G3DSA:2.40.30.10 469 558 4.3E-32 T 23-10-2018 STK_02790 78db9c1facf8bf8f3e003a9bd5785b8a 602 Pfam PF11987 Translation-initiation factor 2 352 449 8.8E-15 T 23-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 STK_02790 78db9c1facf8bf8f3e003a9bd5785b8a 602 Gene3D G3DSA:3.40.50.10050 357 460 2.7E-26 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily STK_02790 78db9c1facf8bf8f3e003a9bd5785b8a 602 PRINTS PR00315 GTP-binding elongation factor signature 96 107 6.8E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_02790 78db9c1facf8bf8f3e003a9bd5785b8a 602 PRINTS PR00315 GTP-binding elongation factor signature 132 141 6.8E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_02790 78db9c1facf8bf8f3e003a9bd5785b8a 602 PRINTS PR00315 GTP-binding elongation factor signature 80 90 6.8E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_02790 78db9c1facf8bf8f3e003a9bd5785b8a 602 PRINTS PR00315 GTP-binding elongation factor signature 14 27 6.8E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_02790 78db9c1facf8bf8f3e003a9bd5785b8a 602 Gene3D G3DSA:3.40.50.300 8 232 6.2E-65 T 23-10-2018 STK_02790 78db9c1facf8bf8f3e003a9bd5785b8a 602 Pfam PF00009 Elongation factor Tu GTP binding domain 14 221 1.3E-32 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_02790 78db9c1facf8bf8f3e003a9bd5785b8a 602 SUPERFAMILY SSF52156 339 461 1.96E-28 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily STK_02790 78db9c1facf8bf8f3e003a9bd5785b8a 602 SUPERFAMILY SSF50447 468 593 2.29E-28 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily STK_02790 78db9c1facf8bf8f3e003a9bd5785b8a 602 Hamap MF_00100_A Translation initiation factor IF-2 [infB]. 8 598 42.028 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 STK_02790 78db9c1facf8bf8f3e003a9bd5785b8a 602 TIGRFAM TIGR00491 aIF-2: translation initiation factor aIF-2 9 591 4.7E-252 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 STK_02790 78db9c1facf8bf8f3e003a9bd5785b8a 602 Pfam PF03144 Elongation factor Tu domain 2 252 330 4.3E-12 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 STK_02790 78db9c1facf8bf8f3e003a9bd5785b8a 602 SUPERFAMILY SSF52540 5 293 4.09E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_12340 c5bc553086e60b705df086a778e8b9df 359 SUPERFAMILY SSF51735 2 356 2.4E-79 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_12340 c5bc553086e60b705df086a778e8b9df 359 Pfam PF01658 Myo-inositol-1-phosphate synthase 191 301 4.9E-32 T 23-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 STK_12340 c5bc553086e60b705df086a778e8b9df 359 SUPERFAMILY SSF55347 189 301 3.01E-32 T 23-10-2018 STK_12340 c5bc553086e60b705df086a778e8b9df 359 Gene3D G3DSA:3.30.360.10 190 302 7.9E-110 T 23-10-2018 STK_12340 c5bc553086e60b705df086a778e8b9df 359 PIRSF PIRSF015578 1 359 2.0E-98 T 23-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 STK_12340 c5bc553086e60b705df086a778e8b9df 359 Gene3D G3DSA:3.40.50.720 2 346 7.9E-110 T 23-10-2018 STK_01920 67b020ef02389aa840842304281801fe 285 SUPERFAMILY SSF56059 80 282 5.83E-43 T 23-10-2018 STK_01920 67b020ef02389aa840842304281801fe 285 TIGRFAM TIGR02144 LysX_arch: lysine biosynthesis enzyme LysX 3 285 3.1E-107 T 23-10-2018 IPR011870 Lysine biosynthesis enzyme LysX GO:0003824|GO:0005524|GO:0009085 STK_01920 67b020ef02389aa840842304281801fe 285 Gene3D G3DSA:3.40.50.20 2 104 7.8E-23 T 23-10-2018 STK_01920 67b020ef02389aa840842304281801fe 285 Gene3D G3DSA:3.30.1490.20 106 174 5.2E-24 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 STK_01920 67b020ef02389aa840842304281801fe 285 SUPERFAMILY SSF52440 3 90 5.47E-24 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily STK_01920 67b020ef02389aa840842304281801fe 285 Pfam PF08443 RimK-like ATP-grasp domain 89 279 9.8E-33 T 23-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 STK_01920 67b020ef02389aa840842304281801fe 285 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 3 279 5.8E-77 T 23-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 STK_01920 67b020ef02389aa840842304281801fe 285 Gene3D G3DSA:3.30.470.80 175 285 1.3E-27 T 23-10-2018 STK_08180 3154f6a7f6286d33a506a9c1a9b71b5b 569 Pfam PF00534 Glycosyl transferases group 1 345 498 1.9E-32 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 STK_08180 3154f6a7f6286d33a506a9c1a9b71b5b 569 Gene3D G3DSA:3.40.50.2000 15 301 4.3E-36 T 23-10-2018 STK_08180 3154f6a7f6286d33a506a9c1a9b71b5b 569 Pfam PF08323 Starch synthase catalytic domain 16 256 2.8E-32 T 23-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 STK_08180 3154f6a7f6286d33a506a9c1a9b71b5b 569 SUPERFAMILY SSF53756 16 556 9.77E-74 T 23-10-2018 STK_08180 3154f6a7f6286d33a506a9c1a9b71b5b 569 Gene3D G3DSA:3.40.50.2000 329 557 1.1E-42 T 23-10-2018 STK_21560 c15b5302e53ee2e039ff13f01e42b71a 250 PIRSF PIRSF005956 1 250 9.0E-89 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family STK_21560 c15b5302e53ee2e039ff13f01e42b71a 250 TIGRFAM TIGR00259 thylakoid_BtpA: membrane complex biogenesis protein, BtpA family 3 246 3.0E-67 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family STK_21560 c15b5302e53ee2e039ff13f01e42b71a 250 ProDom PD011184 BTPA I PHOTOSYSTEM BIOGENESIS ASSEMBLY SGCQ TRIPHOSPHATASE NUCLEOSIDE PAE3553 ENZYME 23 195 6.0E-95 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family STK_21560 c15b5302e53ee2e039ff13f01e42b71a 250 Pfam PF03437 BtpA family 3 245 2.6E-74 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family STK_21560 c15b5302e53ee2e039ff13f01e42b71a 250 SUPERFAMILY SSF51366 27 247 1.29E-14 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 STK_21150 f9089291950a6f9aad352e5b33dcd51e 306 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 2 297 4.6E-77 T 23-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain STK_21150 f9089291950a6f9aad352e5b33dcd51e 306 SUPERFAMILY SSF53590 2 305 4.32E-90 T 23-10-2018 IPR036452 Ribonucleoside hydrolase-like STK_21150 f9089291950a6f9aad352e5b33dcd51e 306 Gene3D G3DSA:3.90.245.10 1 305 6.4E-116 T 23-10-2018 IPR036452 Ribonucleoside hydrolase-like STK_21150 f9089291950a6f9aad352e5b33dcd51e 306 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 7 17 - T 23-10-2018 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 STK_13750 095ac1adcca031e6369703177443965a 153 Pfam PF01090 Ribosomal protein S19e 5 139 2.0E-43 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_13750 095ac1adcca031e6369703177443965a 153 Hamap MF_01474 30S ribosomal protein S19e [rps19e]. 1 149 30.142 T 23-10-2018 IPR027548 Ribosomal protein S19e, archaeal GO:0003735|GO:0005840|GO:0006412 STK_13750 095ac1adcca031e6369703177443965a 153 SUPERFAMILY SSF46785 3 151 5.65E-45 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_13750 095ac1adcca031e6369703177443965a 153 ProDom PD003854 RIBOSOMAL 40S RIBONUCLEOPROTEIN S19 S19E 30S MULTIGENE FAMILY S19 SSU 3 119 5.0E-63 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_13750 095ac1adcca031e6369703177443965a 153 Gene3D G3DSA:1.10.10.2700 1 151 1.8E-44 T 23-10-2018 IPR038111 Ribosomal protein S19e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_13750 095ac1adcca031e6369703177443965a 153 SMART SM01413 3 140 9.6E-70 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_06330 938463a9d7b22131659784aea6375481 250 Gene3D G3DSA:3.40.50.1220 13 235 1.4E-83 T 23-10-2018 STK_06330 938463a9d7b22131659784aea6375481 250 Hamap MF_01968 NAD-dependent protein deacetylase [cobB]. 5 238 62.745 T 23-10-2018 IPR028628 Sirtuin, class U GO:0034979|GO:0051287 STK_06330 938463a9d7b22131659784aea6375481 250 SUPERFAMILY SSF52467 3 241 1.33E-82 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily STK_06330 938463a9d7b22131659784aea6375481 250 Gene3D G3DSA:3.30.1600.10 30 165 1.4E-83 T 23-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily STK_06330 938463a9d7b22131659784aea6375481 250 Pfam PF02146 Sir2 family 21 193 2.0E-53 T 23-10-2018 IPR003000 Sirtuin family GO:0070403 STK_14330 3c95afb9a80f15a867afa737ed82bbd0 701 Pfam PF01496 V-type ATPase 116kDa subunit family 574 693 9.6E-9 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 STK_14330 3c95afb9a80f15a867afa737ed82bbd0 701 Pfam PF01496 V-type ATPase 116kDa subunit family 191 405 5.4E-27 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 STK_13690 b65de5fadc9bb1cb7373a6a0aa8d831b 152 Gene3D G3DSA:2.30.30.30 95 152 4.2E-22 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 STK_13690 b65de5fadc9bb1cb7373a6a0aa8d831b 152 Gene3D G3DSA:3.30.70.940 6 91 7.8E-24 T 23-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 STK_13690 b65de5fadc9bb1cb7373a6a0aa8d831b 152 SMART SM00738 6 91 5.4E-23 T 23-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 STK_13690 b65de5fadc9bb1cb7373a6a0aa8d831b 152 Pfam PF00467 KOW motif 99 128 7.7E-8 T 23-10-2018 IPR005824 KOW STK_13690 b65de5fadc9bb1cb7373a6a0aa8d831b 152 SMART SM00739 96 123 6.1E-6 T 23-10-2018 IPR005824 KOW STK_13690 b65de5fadc9bb1cb7373a6a0aa8d831b 152 TIGRFAM TIGR00405 KOW_elon_Spt5: transcription elongation factor Spt5 10 152 2.3E-35 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 STK_13690 b65de5fadc9bb1cb7373a6a0aa8d831b 152 SUPERFAMILY SSF50104 58 151 3.31E-16 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily STK_13690 b65de5fadc9bb1cb7373a6a0aa8d831b 152 Pfam PF03439 Early transcription elongation factor of RNA pol II, NGN section 8 87 1.8E-23 T 23-10-2018 IPR005100 NGN domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 STK_13690 b65de5fadc9bb1cb7373a6a0aa8d831b 152 Hamap MF_00950 Transcription elongation factor Spt5 [spt5]. 8 152 36.381 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 STK_09700 1a3ee33a5ee4b046a2774b11eb9b5bac 104 Gene3D G3DSA:1.20.120.330 34 96 3.5E-18 T 23-10-2018 STK_09700 1a3ee33a5ee4b046a2774b11eb9b5bac 104 Pfam PF05942 Archaeal PaREP1/PaREP8 family 35 89 2.6E-15 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_00830 27cd35d4e17093d1f64d8c49560d21ab 118 Pfam PF07849 Protein of unknown function (DUF1641) 75 113 8.4E-12 T 23-10-2018 IPR012440 Protein of unknown function DUF1641 STK_22450 115a3a6cfd77d61739a99f6e8e18b1b4 311 SUPERFAMILY SSF53697 35 290 2.62E-46 T 23-10-2018 STK_22450 115a3a6cfd77d61739a99f6e8e18b1b4 311 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 169 296 7.4E-26 T 23-10-2018 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 STK_22450 115a3a6cfd77d61739a99f6e8e18b1b4 311 Gene3D G3DSA:3.40.50.10490 162 297 1.4E-21 T 23-10-2018 STK_22450 115a3a6cfd77d61739a99f6e8e18b1b4 311 Gene3D G3DSA:3.40.50.10490 3 151 7.0E-27 T 23-10-2018 STK_22450 115a3a6cfd77d61739a99f6e8e18b1b4 311 TIGRFAM TIGR02128 G6PI_arch: bifunctional phosphoglucose/phosphomannose isomerase 8 297 1.0E-106 T 23-10-2018 IPR011857 Bifunctional phosphoglucose/phosphomannose isomerase GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 STK_08220 eee244c4f0862786ec1d298cd56a9276 240 Pfam PF01144 Coenzyme A transferase 4 201 1.9E-33 T 23-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 STK_08220 eee244c4f0862786ec1d298cd56a9276 240 SUPERFAMILY SSF100950 3 236 1.26E-45 T 23-10-2018 IPR037171 NagB/RpiA transferase-like STK_08220 eee244c4f0862786ec1d298cd56a9276 240 SMART SM00882 4 202 0.0056 T 23-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 STK_08220 eee244c4f0862786ec1d298cd56a9276 240 Gene3D G3DSA:3.40.1080.10 2 234 1.3E-36 T 23-10-2018 STK_23920 561baa0fcf59ee016eb6bc4aecf354b0 217 Pfam PF00355 Rieske [2Fe-2S] domain 82 165 3.5E-6 T 23-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 STK_23920 561baa0fcf59ee016eb6bc4aecf354b0 217 Gene3D G3DSA:2.102.10.10 75 205 3.6E-24 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 STK_23920 561baa0fcf59ee016eb6bc4aecf354b0 217 SUPERFAMILY SSF50022 77 201 3.4E-22 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 STK_23920 561baa0fcf59ee016eb6bc4aecf354b0 217 TIGRFAM TIGR02694 arsenite_ox_S: arsenite oxidase, small subunit 77 200 2.5E-28 T 23-10-2018 IPR014067 Arsenite oxidase, small subunit MetaCyc: PWY-7429 STK_12660 dc1de3ea7dc3fe0e383bbe403f172172 233 Pfam PF01269 Fibrillarin 9 231 7.5E-104 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 STK_12660 dc1de3ea7dc3fe0e383bbe403f172172 233 Hamap MF_00351 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase [flpA]. 20 231 43.273 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 STK_12660 dc1de3ea7dc3fe0e383bbe403f172172 233 Gene3D G3DSA:3.30.200.20 1 54 1.6E-27 T 23-10-2018 STK_12660 dc1de3ea7dc3fe0e383bbe403f172172 233 SMART SM01206 7 232 4.5E-151 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 STK_12660 dc1de3ea7dc3fe0e383bbe403f172172 233 PRINTS PR00052 Fibrillarin signature 157 186 3.0E-72 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 STK_12660 dc1de3ea7dc3fe0e383bbe403f172172 233 PRINTS PR00052 Fibrillarin signature 209 230 3.0E-72 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 STK_12660 dc1de3ea7dc3fe0e383bbe403f172172 233 PRINTS PR00052 Fibrillarin signature 77 98 3.0E-72 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 STK_12660 dc1de3ea7dc3fe0e383bbe403f172172 233 PRINTS PR00052 Fibrillarin signature 27 46 3.0E-72 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 STK_12660 dc1de3ea7dc3fe0e383bbe403f172172 233 PRINTS PR00052 Fibrillarin signature 127 156 3.0E-72 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 STK_12660 dc1de3ea7dc3fe0e383bbe403f172172 233 PRINTS PR00052 Fibrillarin signature 50 69 3.0E-72 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 STK_12660 dc1de3ea7dc3fe0e383bbe403f172172 233 PRINTS PR00052 Fibrillarin signature 102 119 3.0E-72 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 STK_12660 dc1de3ea7dc3fe0e383bbe403f172172 233 ProSitePatterns PS00566 Fibrillarin signature. 102 116 - T 23-10-2018 IPR020813 Fibrillarin, conserved site GO:0003723|GO:0006364|GO:0008168 STK_12660 dc1de3ea7dc3fe0e383bbe403f172172 233 PIRSF PIRSF006540 1 233 1.0E-101 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 STK_12660 dc1de3ea7dc3fe0e383bbe403f172172 233 Gene3D G3DSA:3.40.50.150 55 232 2.8E-72 T 23-10-2018 STK_12660 dc1de3ea7dc3fe0e383bbe403f172172 233 SUPERFAMILY SSF53335 7 230 2.82E-50 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_02680 1ad7aa6dded59034eefc0bf46f3b7640 102 PRINTS PR00971 Ribosomal protein S10 family signature 4 17 5.7E-14 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_02680 1ad7aa6dded59034eefc0bf46f3b7640 102 PRINTS PR00971 Ribosomal protein S10 family signature 39 54 5.7E-14 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_02680 1ad7aa6dded59034eefc0bf46f3b7640 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 5.7E-14 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_02680 1ad7aa6dded59034eefc0bf46f3b7640 102 SMART SM01403 6 100 3.0E-39 T 23-10-2018 IPR027486 Ribosomal protein S10 domain STK_02680 1ad7aa6dded59034eefc0bf46f3b7640 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 2 101 24.721 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_02680 1ad7aa6dded59034eefc0bf46f3b7640 102 TIGRFAM TIGR01046 uS10_euk_arch: ribosomal protein uS10 4 101 8.6E-45 T 23-10-2018 IPR005729 Ribosomal protein S10, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_02680 1ad7aa6dded59034eefc0bf46f3b7640 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 28 43 - T 23-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_02680 1ad7aa6dded59034eefc0bf46f3b7640 102 Gene3D G3DSA:3.30.70.600 2 101 7.8E-33 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily STK_02680 1ad7aa6dded59034eefc0bf46f3b7640 102 Pfam PF00338 Ribosomal protein S10p/S20e 6 99 1.1E-27 T 23-10-2018 IPR027486 Ribosomal protein S10 domain STK_02680 1ad7aa6dded59034eefc0bf46f3b7640 102 SUPERFAMILY SSF54999 4 101 1.57E-29 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily STK_16090 b4daa36a850e8633ed1f1b2c8f68efcb 270 SUPERFAMILY SSF103481 176 269 4.18E-15 T 23-10-2018 STK_16090 b4daa36a850e8633ed1f1b2c8f68efcb 270 SUPERFAMILY SSF103481 55 134 4.84E-11 T 23-10-2018 STK_16090 b4daa36a850e8633ed1f1b2c8f68efcb 270 Pfam PF00892 EamA-like transporter family 4 132 2.7E-12 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 STK_16090 b4daa36a850e8633ed1f1b2c8f68efcb 270 Pfam PF00892 EamA-like transporter family 141 269 1.6E-17 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 STK_17850 eb6ebe1aefa4d80133a10877ec4f2915 155 PIRSF PIRSF000239 1 155 2.9E-30 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 STK_17850 eb6ebe1aefa4d80133a10877ec4f2915 155 SUPERFAMILY SSF52833 1 154 3.74E-53 T 23-10-2018 IPR036249 Thioredoxin-like superfamily STK_17850 eb6ebe1aefa4d80133a10877ec4f2915 155 Pfam PF00578 AhpC/TSA family 4 132 2.4E-40 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 STK_17850 eb6ebe1aefa4d80133a10877ec4f2915 155 Gene3D G3DSA:3.40.30.10 1 155 8.7E-55 T 23-10-2018 STK_02940 3f55bf291883041dbbf327d42800df0c 202 Gene3D G3DSA:3.40.190.10 11 93 3.1E-16 T 23-10-2018 STK_02940 3f55bf291883041dbbf327d42800df0c 202 SUPERFAMILY SSF55021 104 191 1.51E-24 T 23-10-2018 STK_02940 3f55bf291883041dbbf327d42800df0c 202 Gene3D G3DSA:3.30.70.260 106 198 4.5E-28 T 23-10-2018 STK_02940 3f55bf291883041dbbf327d42800df0c 202 Pfam PF00800 Prephenate dehydratase 3 105 1.2E-21 T 23-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 STK_02940 3f55bf291883041dbbf327d42800df0c 202 SUPERFAMILY SSF53850 4 107 1.63E-19 T 23-10-2018 STK_23420 dabe16b2025b8c4f0d0ca74c4c897031 303 Pfam PF03186 CobD/Cbib protein 5 268 8.5E-68 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 STK_23420 dabe16b2025b8c4f0d0ca74c4c897031 303 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 290 58.773 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 STK_23420 dabe16b2025b8c4f0d0ca74c4c897031 303 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 4 277 4.6E-60 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 STK_06660 6612c0aa54b68bc83e0b41761b99c5fc 478 Gene3D G3DSA:1.20.1720.10 12 247 4.1E-45 T 23-10-2018 STK_06660 6612c0aa54b68bc83e0b41761b99c5fc 478 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 386 1.9E-70 T 23-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 STK_06660 6612c0aa54b68bc83e0b41761b99c5fc 478 SUPERFAMILY SSF103473 8 470 4.32E-70 T 23-10-2018 IPR036259 MFS transporter superfamily STK_06660 6612c0aa54b68bc83e0b41761b99c5fc 478 Pfam PF07690 Major Facilitator Superfamily 16 406 1.3E-54 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_06660 6612c0aa54b68bc83e0b41761b99c5fc 478 Gene3D G3DSA:1.20.1250.20 255 471 2.1E-19 T 23-10-2018 STK_24050 5f8844a84442b76dc5e4a8166aed2550 219 SMART SM00986 44 207 8.2E-30 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 STK_24050 5f8844a84442b76dc5e4a8166aed2550 219 Pfam PF03167 Uracil DNA glycosylase superfamily 44 203 1.3E-34 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 STK_24050 5f8844a84442b76dc5e4a8166aed2550 219 SMART SM00987 44 207 8.2E-30 T 23-10-2018 STK_24050 5f8844a84442b76dc5e4a8166aed2550 219 SUPERFAMILY SSF52141 14 212 1.96E-50 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 STK_24050 5f8844a84442b76dc5e4a8166aed2550 219 Gene3D G3DSA:3.40.470.10 4 215 2.1E-66 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 STK_23430 1320c1977a191e662b7bfe1624ce11d6 247 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 247 18.253 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 STK_23430 1320c1977a191e662b7bfe1624ce11d6 247 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 4 230 1.6E-33 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 STK_23430 1320c1977a191e662b7bfe1624ce11d6 247 Pfam PF02654 Cobalamin-5-phosphate synthase 11 229 3.0E-29 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 STK_02720 8599b1e2bec58a696cd51016af364092 147 Gene3D G3DSA:2.40.50.140 28 147 2.7E-49 T 23-10-2018 STK_02720 8599b1e2bec58a696cd51016af364092 147 Pfam PF00164 Ribosomal protein S12/S23 32 145 9.7E-48 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_02720 8599b1e2bec58a696cd51016af364092 147 TIGRFAM TIGR00982 uS12_E_A: ribosomal protein uS12 9 147 6.3E-76 T 23-10-2018 IPR005680 Ribosomal protein S23, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_02720 8599b1e2bec58a696cd51016af364092 147 SUPERFAMILY SSF50249 23 145 3.0E-36 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_02720 8599b1e2bec58a696cd51016af364092 147 ProSitePatterns PS00055 Ribosomal protein S12 signature. 63 70 - T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_02720 8599b1e2bec58a696cd51016af364092 147 Hamap MF_00403_A 30S ribosomal protein S12 [rpsL]. 1 147 42.607 T 23-10-2018 IPR022863 Ribosomal protein S12, archaea STK_02720 8599b1e2bec58a696cd51016af364092 147 PIRSF PIRSF002133 19 147 3.4E-34 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_14280 37a40b9d2091ab2e52864a330f959803 161 Pfam PF13847 Methyltransferase domain 32 145 6.0E-11 T 23-10-2018 IPR025714 Methyltransferase domain STK_14280 37a40b9d2091ab2e52864a330f959803 161 Gene3D G3DSA:3.40.50.150 1 161 3.9E-54 T 23-10-2018 STK_14280 37a40b9d2091ab2e52864a330f959803 161 SUPERFAMILY SSF53335 7 155 8.36E-35 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_15820 ef2eace001008b7b69dcd9593754cff1 274 Gene3D G3DSA:3.40.50.300 1 231 3.0E-63 T 23-10-2018 STK_15820 ef2eace001008b7b69dcd9593754cff1 274 SUPERFAMILY SSF52540 2 224 9.87E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_15820 ef2eace001008b7b69dcd9593754cff1 274 SMART SM00382 27 215 4.2E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_15820 ef2eace001008b7b69dcd9593754cff1 274 Pfam PF00005 ABC transporter 19 159 6.1E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_11470 3eee6a965a29069fb8c1c526b8bcfbe0 352 PIRSF PIRSF029347 168 335 3.5E-8 T 23-10-2018 IPR014555 RecF-like STK_11470 3eee6a965a29069fb8c1c526b8bcfbe0 352 PIRSF PIRSF029347 1 168 1.2E-10 T 23-10-2018 IPR014555 RecF-like STK_11470 3eee6a965a29069fb8c1c526b8bcfbe0 352 Gene3D G3DSA:3.40.50.300 173 326 7.0E-12 T 23-10-2018 STK_11470 3eee6a965a29069fb8c1c526b8bcfbe0 352 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 23 303 6.9E-37 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_11470 3eee6a965a29069fb8c1c526b8bcfbe0 352 SUPERFAMILY SSF52540 2 313 1.93E-27 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_11470 3eee6a965a29069fb8c1c526b8bcfbe0 352 Gene3D G3DSA:3.40.50.300 1 130 2.9E-12 T 23-10-2018 STK_11470 3eee6a965a29069fb8c1c526b8bcfbe0 352 SMART SM00382 20 317 9.8E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_14040 243185668760789eb82d037806b67001 873 SUPERFAMILY SSF52540 46 381 5.62E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_14040 243185668760789eb82d037806b67001 873 Pfam PF00270 DEAD/DEAH box helicase 34 215 2.0E-26 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 STK_14040 243185668760789eb82d037806b67001 873 Pfam PF00271 Helicase conserved C-terminal domain 268 376 4.2E-18 T 23-10-2018 IPR001650 Helicase, C-terminal STK_14040 243185668760789eb82d037806b67001 873 SMART SM00490 290 380 9.0E-17 T 23-10-2018 IPR001650 Helicase, C-terminal STK_14040 243185668760789eb82d037806b67001 873 Gene3D G3DSA:3.40.50.300 250 412 1.8E-26 T 23-10-2018 STK_14040 243185668760789eb82d037806b67001 873 Gene3D G3DSA:3.40.50.300 13 238 2.5E-48 T 23-10-2018 STK_14040 243185668760789eb82d037806b67001 873 SMART SM00487 29 245 2.2E-33 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain STK_14040 243185668760789eb82d037806b67001 873 PIRSF PIRSF037307 4 872 6.9E-279 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 STK_14040 243185668760789eb82d037806b67001 873 Pfam PF08494 DEAD/H associated 638 827 7.5E-54 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 STK_07140 bf00e3b6c2d6ff93250f7b417ef77ea2 266 Pfam PF06314 Acetoacetate decarboxylase (ADC) 7 259 2.4E-58 T 23-10-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 STK_07140 bf00e3b6c2d6ff93250f7b417ef77ea2 266 SUPERFAMILY SSF160104 4 256 6.93E-37 T 23-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 STK_07140 bf00e3b6c2d6ff93250f7b417ef77ea2 266 Gene3D G3DSA:2.40.400.10 2 264 1.6E-65 T 23-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 STK_17350 dfa64398f97dfb02ce4a72d75802a219 298 Gene3D G3DSA:3.40.50.300 1 241 5.5E-57 T 23-10-2018 STK_17350 dfa64398f97dfb02ce4a72d75802a219 298 Pfam PF00005 ABC transporter 17 160 1.6E-24 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_17350 dfa64398f97dfb02ce4a72d75802a219 298 SUPERFAMILY SSF52540 2 222 2.61E-54 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_17350 dfa64398f97dfb02ce4a72d75802a219 298 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 STK_17350 dfa64398f97dfb02ce4a72d75802a219 298 SMART SM00382 26 209 9.5E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_03350 f03071ab320500424dac902d36744bf1 322 Pfam PF00145 C-5 cytosine-specific DNA methylase 5 310 5.6E-52 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 STK_03350 f03071ab320500424dac902d36744bf1 322 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 5 310 3.0E-45 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 STK_03350 f03071ab320500424dac902d36744bf1 322 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 117 131 4.0E-13 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 STK_03350 f03071ab320500424dac902d36744bf1 322 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 161 174 4.0E-13 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 STK_03350 f03071ab320500424dac902d36744bf1 322 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 4 20 4.0E-13 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 STK_03350 f03071ab320500424dac902d36744bf1 322 Gene3D G3DSA:3.40.50.150 6 308 5.1E-72 T 23-10-2018 STK_03350 f03071ab320500424dac902d36744bf1 322 Gene3D G3DSA:3.90.120.10 156 301 5.1E-72 T 23-10-2018 STK_03350 f03071ab320500424dac902d36744bf1 322 SUPERFAMILY SSF53335 3 311 1.14E-78 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_05430 f1bdc7e73ec4be0224f054b8c296f494 139 Gene3D G3DSA:3.30.479.10 1 138 3.8E-28 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 STK_05430 f1bdc7e73ec4be0224f054b8c296f494 139 SUPERFAMILY SSF55620 10 138 1.95E-33 T 23-10-2018 STK_05430 f1bdc7e73ec4be0224f054b8c296f494 139 PIRSF PIRSF006113 2 82 1.1E-15 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 STK_05430 f1bdc7e73ec4be0224f054b8c296f494 139 PIRSF PIRSF006113 88 139 0.15 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 STK_05430 f1bdc7e73ec4be0224f054b8c296f494 139 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 11 136 4.4E-23 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 STK_06830 2233ca42f3d7004570508baf0dc17f02 370 Gene3D G3DSA:3.40.50.150 83 367 6.0E-65 T 23-10-2018 STK_06830 2233ca42f3d7004570508baf0dc17f02 370 SUPERFAMILY SSF53335 109 366 2.01E-52 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_06830 2233ca42f3d7004570508baf0dc17f02 370 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 161 175 4.6E-20 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase STK_06830 2233ca42f3d7004570508baf0dc17f02 370 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 301 317 4.6E-20 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase STK_06830 2233ca42f3d7004570508baf0dc17f02 370 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 190 200 4.6E-20 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase STK_06830 2233ca42f3d7004570508baf0dc17f02 370 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 254 266 4.6E-20 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase STK_06830 2233ca42f3d7004570508baf0dc17f02 370 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 351 368 4.6E-20 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase STK_06830 2233ca42f3d7004570508baf0dc17f02 370 Pfam PF01189 16S rRNA methyltransferase RsmB/F 179 366 1.8E-39 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 STK_19410 ddb9ad19989a2cf7624b2678b291341f 354 Gene3D G3DSA:3.40.50.300 198 331 1.5E-9 T 23-10-2018 STK_19410 ddb9ad19989a2cf7624b2678b291341f 354 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 219 308 2.5E-14 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_19410 ddb9ad19989a2cf7624b2678b291341f 354 Gene3D G3DSA:3.40.50.300 1 134 8.5E-14 T 23-10-2018 STK_19410 ddb9ad19989a2cf7624b2678b291341f 354 SUPERFAMILY SSF52540 1 327 3.75E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_19410 ddb9ad19989a2cf7624b2678b291341f 354 PIRSF PIRSF029347 206 343 3.0E-9 T 23-10-2018 IPR014555 RecF-like STK_19410 ddb9ad19989a2cf7624b2678b291341f 354 PIRSF PIRSF029347 1 50 1.3E-10 T 23-10-2018 IPR014555 RecF-like STK_19410 ddb9ad19989a2cf7624b2678b291341f 354 Pfam PF13175 AAA ATPase domain 1 81 7.7E-13 T 23-10-2018 STK_10190 13f88ff7bc265d1a24df72a826a8e7eb 372 Gene3D G3DSA:3.30.465.10 107 196 6.3E-8 T 23-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 STK_10190 13f88ff7bc265d1a24df72a826a8e7eb 372 Gene3D G3DSA:3.30.43.10 6 93 4.5E-14 T 23-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 STK_10190 13f88ff7bc265d1a24df72a826a8e7eb 372 Pfam PF01565 FAD binding domain 39 166 2.1E-17 T 23-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 STK_10190 13f88ff7bc265d1a24df72a826a8e7eb 372 SUPERFAMILY SSF56176 11 195 4.44E-27 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 STK_23150 3137f5237cc9b2f0ef0e70e6b098791a 178 SUPERFAMILY SSF53218 10 176 6.94E-39 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily STK_23150 3137f5237cc9b2f0ef0e70e6b098791a 178 SMART SM00852 19 172 1.8E-26 T 23-10-2018 IPR001453 MoaB/Mog domain STK_23150 3137f5237cc9b2f0ef0e70e6b098791a 178 Gene3D G3DSA:3.40.980.10 1 178 2.7E-48 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily STK_23150 3137f5237cc9b2f0ef0e70e6b098791a 178 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 17 167 1.8E-31 T 23-10-2018 IPR001453 MoaB/Mog domain STK_23150 3137f5237cc9b2f0ef0e70e6b098791a 178 Pfam PF00994 Probable molybdopterin binding domain 20 170 1.4E-34 T 23-10-2018 IPR001453 MoaB/Mog domain STK_23150 3137f5237cc9b2f0ef0e70e6b098791a 178 PIRSF PIRSF006443 2 178 2.5E-57 T 23-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 STK_08830 18f24faa2b1cc62f705ac137f00c40b9 119 Pfam PF02635 DsrE/DsrF-like family 17 119 1.9E-9 T 23-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein STK_08830 18f24faa2b1cc62f705ac137f00c40b9 119 Gene3D G3DSA:3.40.1260.10 3 119 1.5E-21 T 23-10-2018 IPR027396 DsrEFH-like STK_08830 18f24faa2b1cc62f705ac137f00c40b9 119 SUPERFAMILY SSF75169 2 119 3.03E-17 T 23-10-2018 IPR027396 DsrEFH-like STK_03950 52ca95728a14b0f31bbcd18801fd34ca 225 Gene3D G3DSA:3.30.70.270 117 223 2.3E-22 T 23-10-2018 STK_03950 52ca95728a14b0f31bbcd18801fd34ca 225 Gene3D G3DSA:3.30.70.1230 1 116 2.7E-22 T 23-10-2018 IPR029787 Nucleotide cyclase STK_03950 52ca95728a14b0f31bbcd18801fd34ca 225 ProDom PD313320 GTP III HYDROLASE CYCLOHYDROLASE RIBOFLAVIN BIOSYNTHESIS 3.5.4.- FAMILY MAGNESIUM GGDN 1 222 5.0E-126 T 23-10-2018 IPR007839 GTP cyclohydrolase III GO:0003933|GO:0009058 KEGG: 00740+3.5.4.29|MetaCyc: PWY-6167 STK_03950 52ca95728a14b0f31bbcd18801fd34ca 225 Hamap MF_00608 GTP cyclohydrolase III [gch3]. 3 222 35.804 T 23-10-2018 IPR007839 GTP cyclohydrolase III GO:0003933|GO:0009058 KEGG: 00740+3.5.4.29|MetaCyc: PWY-6167 STK_03950 52ca95728a14b0f31bbcd18801fd34ca 225 Pfam PF05165 GTP cyclohydrolase III 103 213 9.1E-13 T 23-10-2018 IPR007839 GTP cyclohydrolase III GO:0003933|GO:0009058 KEGG: 00740+3.5.4.29|MetaCyc: PWY-6167 STK_03950 52ca95728a14b0f31bbcd18801fd34ca 225 Pfam PF05165 GTP cyclohydrolase III 6 101 9.8E-13 T 23-10-2018 IPR007839 GTP cyclohydrolase III GO:0003933|GO:0009058 KEGG: 00740+3.5.4.29|MetaCyc: PWY-6167 STK_03950 52ca95728a14b0f31bbcd18801fd34ca 225 PIRSF PIRSF009265 1 225 7.5E-73 T 23-10-2018 IPR007839 GTP cyclohydrolase III GO:0003933|GO:0009058 KEGG: 00740+3.5.4.29|MetaCyc: PWY-6167 STK_14670 c8b8f6668cee04b4db8c3176a247c6c8 118 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 38 111 6.9E-32 T 23-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 STK_14670 c8b8f6668cee04b4db8c3176a247c6c8 118 Gene3D G3DSA:3.10.20.400 5 102 3.6E-35 T 23-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 STK_14670 c8b8f6668cee04b4db8c3176a247c6c8 118 SUPERFAMILY SSF141734 12 114 1.22E-42 T 23-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 STK_14670 c8b8f6668cee04b4db8c3176a247c6c8 118 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 12 115 30.471 T 23-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 STK_14670 c8b8f6668cee04b4db8c3176a247c6c8 118 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 62 111 2.0E-24 T 23-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 STK_12830 d96c2d6df56be5771c0ce99ab0dec3ad 472 Pfam PF01425 Amidase 18 449 2.1E-146 T 23-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 STK_12830 d96c2d6df56be5771c0ce99ab0dec3ad 472 SUPERFAMILY SSF75304 3 462 1.44E-143 T 23-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 STK_12830 d96c2d6df56be5771c0ce99ab0dec3ad 472 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 8 462 1.6E-181 T 23-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 STK_12830 d96c2d6df56be5771c0ce99ab0dec3ad 472 ProSitePatterns PS00571 Amidases signature. 142 173 - T 23-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 STK_12830 d96c2d6df56be5771c0ce99ab0dec3ad 472 Gene3D G3DSA:3.90.1300.10 3 468 4.6E-173 T 23-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 STK_12830 d96c2d6df56be5771c0ce99ab0dec3ad 472 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 5 463 86.807 T 23-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 STK_17884 e25349594e0d3c2ba1db91a084025777 87 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 65 76 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_17884 e25349594e0d3c2ba1db91a084025777 87 Gene3D G3DSA:3.30.70.20 28 55 1.1E-5 T 23-10-2018 STK_17884 e25349594e0d3c2ba1db91a084025777 87 Gene3D G3DSA:3.30.70.20 56 86 2.8E-9 T 23-10-2018 STK_17884 e25349594e0d3c2ba1db91a084025777 87 SUPERFAMILY SSF54862 19 86 3.87E-23 T 23-10-2018 STK_17884 e25349594e0d3c2ba1db91a084025777 87 Pfam PF14697 4Fe-4S dicluster domain 30 82 3.2E-11 T 23-10-2018 STK_17884 e25349594e0d3c2ba1db91a084025777 87 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 11 85 2.5E-31 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 STK_07130 f2faf58becb24fc0f7b66d1e5770e8f0 478 ProSitePatterns PS00216 Sugar transport proteins signature 1. 87 103 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 STK_07130 f2faf58becb24fc0f7b66d1e5770e8f0 478 Gene3D G3DSA:1.20.1250.20 17 478 5.1E-72 T 23-10-2018 STK_07130 f2faf58becb24fc0f7b66d1e5770e8f0 478 ProSitePatterns PS00217 Sugar transport proteins signature 2. 129 154 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 STK_07130 f2faf58becb24fc0f7b66d1e5770e8f0 478 SUPERFAMILY SSF103473 14 476 1.14E-73 T 23-10-2018 IPR036259 MFS transporter superfamily STK_07130 f2faf58becb24fc0f7b66d1e5770e8f0 478 Pfam PF00083 Sugar (and other) transporter 34 477 1.9E-44 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 STK_10800 5d58b5f87958f0a1734f0b7cb145d008 114 Pfam PF01906 Putative heavy-metal-binding 8 110 2.8E-37 T 23-10-2018 IPR002765 Uncharacterised protein family UPF0145 STK_10800 5d58b5f87958f0a1734f0b7cb145d008 114 Gene3D G3DSA:3.30.110.70 9 114 1.5E-31 T 23-10-2018 STK_10800 5d58b5f87958f0a1734f0b7cb145d008 114 SUPERFAMILY SSF117782 8 111 1.07E-35 T 23-10-2018 IPR035439 UPF0145 domain superfamily STK_10800 5d58b5f87958f0a1734f0b7cb145d008 114 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 8 110 24.656 T 23-10-2018 IPR002765 Uncharacterised protein family UPF0145 STK_08770 78fdc09d46c993825b35f28e21ac2054 411 SUPERFAMILY SSF51004 59 380 2.49E-35 T 23-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily STK_08770 78fdc09d46c993825b35f28e21ac2054 411 Gene3D G3DSA:2.130.10.10 120 400 2.0E-25 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 STK_01730 98353de7049caf2eff7c411f720de680 116 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 16 88 2.6E-15 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal STK_01730 98353de7049caf2eff7c411f720de680 116 SUPERFAMILY SSF46785 12 108 1.16E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_01730 98353de7049caf2eff7c411f720de680 116 Gene3D G3DSA:1.10.10.10 6 112 2.7E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_18300 f3f00ea0e98bec29ee2768759bb2c11f 283 Gene3D G3DSA:3.40.50.300 4 247 2.4E-68 T 23-10-2018 STK_18300 f3f00ea0e98bec29ee2768759bb2c11f 283 SUPERFAMILY SSF52540 3 235 2.68E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_18300 f3f00ea0e98bec29ee2768759bb2c11f 283 Hamap MF_01076 UPF0273 protein . 3 247 58.914 T 23-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like STK_18300 f3f00ea0e98bec29ee2768759bb2c11f 283 PRINTS PR01874 DNA repair protein radA signature 137 161 1.4E-8 T 23-10-2018 STK_18300 f3f00ea0e98bec29ee2768759bb2c11f 283 PRINTS PR01874 DNA repair protein radA signature 15 43 1.4E-8 T 23-10-2018 STK_18300 f3f00ea0e98bec29ee2768759bb2c11f 283 TIGRFAM TIGR03877 thermo_KaiC_1: KaiC domain protein, Ph0284 family 4 241 8.5E-136 T 23-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like STK_18300 f3f00ea0e98bec29ee2768759bb2c11f 283 Pfam PF06745 KaiC 6 239 5.1E-89 T 23-10-2018 IPR014774 KaiC-like domain STK_07790 323eaf997228ae7b7e41f638dc9516cb 583 Gene3D G3DSA:2.140.10.30 117 228 1.7E-6 T 23-10-2018 IPR038554 Dipeptidylpeptidase IV, N-terminal domain superfamily STK_07790 323eaf997228ae7b7e41f638dc9516cb 583 Pfam PF00326 Prolyl oligopeptidase family 373 582 2.8E-47 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 STK_07790 323eaf997228ae7b7e41f638dc9516cb 583 SUPERFAMILY SSF53474 342 582 7.42E-54 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold STK_07790 323eaf997228ae7b7e41f638dc9516cb 583 Gene3D G3DSA:3.40.50.1820 339 583 7.1E-63 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold STK_07790 323eaf997228ae7b7e41f638dc9516cb 583 SUPERFAMILY SSF69304 112 320 4.05E-17 T 23-10-2018 STK_09500 a84b88ebe1a7b685798081aca317b769 166 SUPERFAMILY SSF52540 1 166 2.67E-15 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_09500 a84b88ebe1a7b685798081aca317b769 166 Pfam PF13207 AAA domain 1 117 1.2E-12 T 23-10-2018 STK_09500 a84b88ebe1a7b685798081aca317b769 166 Gene3D G3DSA:3.40.50.300 1 166 7.9E-46 T 23-10-2018 STK_03920 5f8e7feb438713da01af09dc915809ef 218 Gene3D G3DSA:3.90.870.10 3 217 2.7E-59 T 23-10-2018 STK_03920 5f8e7feb438713da01af09dc915809ef 218 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 6 214 2.7E-45 T 23-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 STK_03920 5f8e7feb438713da01af09dc915809ef 218 SUPERFAMILY SSF55821 6 214 3.89E-54 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily STK_24460 ae06a880c148f8dbf86f91555eff4719 276 SMART SM00382 26 214 4.2E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_24460 ae06a880c148f8dbf86f91555eff4719 276 SUPERFAMILY SSF52540 6 211 4.42E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_24460 ae06a880c148f8dbf86f91555eff4719 276 Pfam PF00005 ABC transporter 20 160 3.0E-24 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_24460 ae06a880c148f8dbf86f91555eff4719 276 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 STK_24460 ae06a880c148f8dbf86f91555eff4719 276 Gene3D G3DSA:3.40.50.300 1 233 1.3E-54 T 23-10-2018 STK_21870 3484e86e7b1fcb4d790a6449e705462a 385 Gene3D G3DSA:3.40.50.800 265 372 2.1E-20 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily STK_21870 3484e86e7b1fcb4d790a6449e705462a 385 Pfam PF03129 Anticodon binding domain 274 359 1.3E-13 T 23-10-2018 IPR004154 Anticodon-binding STK_21870 3484e86e7b1fcb4d790a6449e705462a 385 Gene3D G3DSA:3.50.80.10 2 134 2.0E-47 T 23-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily STK_21870 3484e86e7b1fcb4d790a6449e705462a 385 SUPERFAMILY SSF52954 266 359 1.33E-19 T 23-10-2018 STK_21870 3484e86e7b1fcb4d790a6449e705462a 385 ProDom PD016189 SYNTHETASE LIGASE THREONYL-TRNA AMINOACYL-TRNA NUCLEOTIDE-BINDING BIOSYNTHESIS ATP-BINDING ZINC METAL-BINDING THRRS 1 134 3.0E-51 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 STK_21870 3484e86e7b1fcb4d790a6449e705462a 385 Pfam PF08915 Archaea-specific editing domain of threonyl-tRNA synthetase 3 134 2.7E-50 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 STK_25540 2136673d891472b1b08823eae21b11d9 650 Gene3D G3DSA:3.20.20.70 217 465 3.4E-15 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_25540 2136673d891472b1b08823eae21b11d9 650 Pfam PF05691 Raffinose synthase or seed imbibition protein Sip1 182 273 4.8E-18 T 23-10-2018 IPR008811 Glycosyl hydrolases 36 STK_25540 2136673d891472b1b08823eae21b11d9 650 Pfam PF05691 Raffinose synthase or seed imbibition protein Sip1 284 547 7.6E-28 T 23-10-2018 IPR008811 Glycosyl hydrolases 36 STK_25540 2136673d891472b1b08823eae21b11d9 650 SUPERFAMILY SSF51445 218 495 7.37E-47 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily STK_21010 6517d54b6beadec5a3055e7eec971587 511 Pfam PF14010 Phosphoenolpyruvate carboxylase 4 511 2.0E-218 T 23-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 STK_21010 6517d54b6beadec5a3055e7eec971587 511 TIGRFAM TIGR02751 PEPCase_arch: phosphoenolpyruvate carboxylase 4 511 5.8E-209 T 23-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 STK_21010 6517d54b6beadec5a3055e7eec971587 511 SUPERFAMILY SSF51621 127 462 9.73E-37 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 STK_21010 6517d54b6beadec5a3055e7eec971587 511 Hamap MF_01904 Phosphoenolpyruvate carboxylase [ppcA]. 3 511 41.174 T 23-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 STK_21010 6517d54b6beadec5a3055e7eec971587 511 PIRSF PIRSF006677 1 511 8.2E-219 T 23-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 STK_22230 6f5000cec794a45d150f0ce0130a4c49 462 Pfam PF00361 Proton-conducting membrane transporter 123 407 1.2E-42 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_15930 87d002dc5c36fb4e2eec42be90d5cfc0 204 Pfam PF04967 HTH DNA binding domain 145 197 5.9E-21 T 23-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain STK_15930 87d002dc5c36fb4e2eec42be90d5cfc0 204 SUPERFAMILY SSF88659 143 201 2.83E-8 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like STK_15930 87d002dc5c36fb4e2eec42be90d5cfc0 204 Gene3D G3DSA:1.10.10.10 138 199 2.3E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_18970 9e57b6cd96d04f8955e0b2c61baa0db3 239 Gene3D G3DSA:3.10.580.10 1 117 1.2E-28 T 23-10-2018 STK_18970 9e57b6cd96d04f8955e0b2c61baa0db3 239 SUPERFAMILY SSF54631 155 235 5.06E-11 T 23-10-2018 STK_18970 9e57b6cd96d04f8955e0b2c61baa0db3 239 Pfam PF00571 CBS domain 59 111 1.5E-14 T 23-10-2018 IPR000644 CBS domain STK_18970 9e57b6cd96d04f8955e0b2c61baa0db3 239 Pfam PF00571 CBS domain 187 237 2.2E-6 T 23-10-2018 IPR000644 CBS domain STK_18970 9e57b6cd96d04f8955e0b2c61baa0db3 239 Pfam PF00571 CBS domain 120 173 4.6E-9 T 23-10-2018 IPR000644 CBS domain STK_18970 9e57b6cd96d04f8955e0b2c61baa0db3 239 Pfam PF00571 CBS domain 3 49 5.4E-10 T 23-10-2018 IPR000644 CBS domain STK_18970 9e57b6cd96d04f8955e0b2c61baa0db3 239 SUPERFAMILY SSF54631 57 174 3.7E-28 T 23-10-2018 STK_18970 9e57b6cd96d04f8955e0b2c61baa0db3 239 SUPERFAMILY SSF54631 1 50 1.5E-10 T 23-10-2018 STK_18970 9e57b6cd96d04f8955e0b2c61baa0db3 239 Gene3D G3DSA:3.10.580.10 118 237 1.4E-23 T 23-10-2018 STK_18970 9e57b6cd96d04f8955e0b2c61baa0db3 239 SMART SM00116 127 174 0.0022 T 23-10-2018 IPR000644 CBS domain STK_18970 9e57b6cd96d04f8955e0b2c61baa0db3 239 SMART SM00116 66 113 1.1E-7 T 23-10-2018 IPR000644 CBS domain STK_18970 9e57b6cd96d04f8955e0b2c61baa0db3 239 SMART SM00116 191 238 0.0019 T 23-10-2018 IPR000644 CBS domain STK_18970 9e57b6cd96d04f8955e0b2c61baa0db3 239 SMART SM00116 10 53 6.8E-4 T 23-10-2018 IPR000644 CBS domain STK_20210 6e4bc7a7762f45bf64ef38779e79ed41 415 SUPERFAMILY SSF53448 54 381 2.06E-30 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_20210 6e4bc7a7762f45bf64ef38779e79ed41 415 ProDom PD339107 ALGINATE ALG8 BIOSYNTHESIS TRANSFERASE TRANSMEMBRANE MEMBRANE 2.4.1.- GLYCOSYL GLYCOSYLTRANSFERASE PRECURSOR 54 304 2.0E-5 T 23-10-2018 STK_20210 6e4bc7a7762f45bf64ef38779e79ed41 415 Gene3D G3DSA:3.90.550.10 35 267 3.4E-21 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_20210 6e4bc7a7762f45bf64ef38779e79ed41 415 Pfam PF13641 Glycosyltransferase like family 2 53 277 2.6E-17 T 23-10-2018 STK_24540 b2cf84d793e6ba4e4c764e86d61f8597 473 Gene3D G3DSA:1.20.1250.20 28 469 1.1E-63 T 23-10-2018 STK_24540 b2cf84d793e6ba4e4c764e86d61f8597 473 SUPERFAMILY SSF103473 1 468 5.36E-65 T 23-10-2018 IPR036259 MFS transporter superfamily STK_24540 b2cf84d793e6ba4e4c764e86d61f8597 473 ProSitePatterns PS00217 Sugar transport proteins signature 2. 130 155 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 STK_24540 b2cf84d793e6ba4e4c764e86d61f8597 473 ProSitePatterns PS00216 Sugar transport proteins signature 1. 88 105 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 STK_24540 b2cf84d793e6ba4e4c764e86d61f8597 473 Pfam PF00083 Sugar (and other) transporter 33 468 4.9E-37 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 STK_21080 f805501731e52662d161f51badba275b 879 SUPERFAMILY SSF52540 1 866 2.83E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_21080 f805501731e52662d161f51badba275b 879 Pfam PF00005 ABC transporter 668 820 6.6E-6 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_21080 f805501731e52662d161f51badba275b 879 Gene3D G3DSA:3.40.50.300 649 877 1.1E-38 T 23-10-2018 STK_21080 f805501731e52662d161f51badba275b 879 Gene3D G3DSA:3.40.50.300 1 250 2.1E-34 T 23-10-2018 STK_21080 f805501731e52662d161f51badba275b 879 SUPERFAMILY SSF52540 1 380 1.95E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_21080 f805501731e52662d161f51badba275b 879 Pfam PF04423 Rad50 zinc hook motif 418 468 8.3E-14 T 23-10-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 STK_21080 f805501731e52662d161f51badba275b 879 SUPERFAMILY SSF75712 392 490 4.71E-18 T 23-10-2018 STK_21080 f805501731e52662d161f51badba275b 879 Hamap MF_00449 DNA double-strand break repair Rad50 ATPase [rad50]. 1 875 13.488 T 23-10-2018 IPR022982 DNA double-strand break repair Rad50 ATPase, archaeal type STK_21080 f805501731e52662d161f51badba275b 879 Gene3D G3DSA:1.10.287.510 390 504 1.4E-12 T 23-10-2018 STK_21080 f805501731e52662d161f51badba275b 879 Pfam PF13476 AAA domain 5 219 1.2E-21 T 23-10-2018 IPR038729 Rad50/SbcC-type AAA domain STK_07950 6b24a4d23c61e61ae56ffe732ea9de0f 172 Pfam PF05942 Archaeal PaREP1/PaREP8 family 15 137 3.3E-26 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_17860 ba3e73adaa9d7e303d7cbeb328a3535e 266 PIRSF PIRSF015582 1 266 1.6E-79 T 23-10-2018 IPR011206 Citrate lyase beta subunit-like STK_17860 ba3e73adaa9d7e303d7cbeb328a3535e 266 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 3 206 1.2E-37 T 23-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 STK_17860 ba3e73adaa9d7e303d7cbeb328a3535e 266 SUPERFAMILY SSF51621 2 217 2.48E-54 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 STK_17860 ba3e73adaa9d7e303d7cbeb328a3535e 266 Gene3D G3DSA:3.20.20.60 1 266 1.4E-84 T 23-10-2018 STK_03430 7fc01337ca3e271aa4f43c1f7ab726a1 637 SMART SM01027 418 540 1.2E-50 T 23-10-2018 IPR022712 Beta-Casp domain STK_03430 7fc01337ca3e271aa4f43c1f7ab726a1 637 SUPERFAMILY SSF56281 179 635 1.4E-134 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_03430 7fc01337ca3e271aa4f43c1f7ab726a1 637 TIGRFAM TIGR03675 arCOG00543: arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein 7 636 3.9E-285 T 23-10-2018 IPR019975 KH-domain/beta-lactamase-domain protein, archaea STK_03430 7fc01337ca3e271aa4f43c1f7ab726a1 637 SMART SM00849 191 406 6.8E-27 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_03430 7fc01337ca3e271aa4f43c1f7ab726a1 637 Gene3D G3DSA:3.30.300.230 11 169 5.7E-57 T 23-10-2018 STK_03430 7fc01337ca3e271aa4f43c1f7ab726a1 637 Pfam PF16661 Metallo-beta-lactamase superfamily domain 197 364 2.8E-14 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_03430 7fc01337ca3e271aa4f43c1f7ab726a1 637 Gene3D G3DSA:3.60.15.10 184 609 4.4E-149 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_03430 7fc01337ca3e271aa4f43c1f7ab726a1 637 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 559 616 8.3E-15 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain STK_03430 7fc01337ca3e271aa4f43c1f7ab726a1 637 Gene3D G3DSA:3.30.300.20 65 135 5.7E-57 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta STK_03430 7fc01337ca3e271aa4f43c1f7ab726a1 637 Gene3D G3DSA:3.40.50.10890 386 571 4.4E-149 T 23-10-2018 STK_03430 7fc01337ca3e271aa4f43c1f7ab726a1 637 Pfam PF10996 Beta-Casp domain 419 539 4.4E-23 T 23-10-2018 IPR022712 Beta-Casp domain STK_03430 7fc01337ca3e271aa4f43c1f7ab726a1 637 Pfam PF17214 KH domain 7 68 6.0E-21 T 23-10-2018 IPR033769 KH domain, archaeal STK_04405 cba26739f088c5f5785773e373266730 81 Gene3D G3DSA:3.30.310.50 1 70 9.8E-9 T 23-10-2018 STK_03270 4fece0ebfce15c96940ae86bb6a13bec 491 Gene3D G3DSA:3.20.20.105 1 356 1.7E-98 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 STK_03270 4fece0ebfce15c96940ae86bb6a13bec 491 SUPERFAMILY SSF88802 365 450 1.37E-9 T 23-10-2018 STK_03270 4fece0ebfce15c96940ae86bb6a13bec 491 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 5 336 1.2E-63 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 STK_03270 4fece0ebfce15c96940ae86bb6a13bec 491 Pfam PF01702 Queuine tRNA-ribosyltransferase 105 330 1.6E-35 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 STK_03270 4fece0ebfce15c96940ae86bb6a13bec 491 TIGRFAM TIGR00432 arcsn_tRNA_tgt: tRNA-guanine(15) transglycosylase 5 466 1.3E-120 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 STK_03270 4fece0ebfce15c96940ae86bb6a13bec 491 Hamap MF_01634 tRNA-guanine(15) transglycosylase [tgtA]. 5 486 44.306 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 STK_03270 4fece0ebfce15c96940ae86bb6a13bec 491 SUPERFAMILY SSF51713 2 356 5.23E-100 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 STK_18490 587884368a118c17f56c516fe49a0298 103 Gene3D G3DSA:3.30.2310.20 5 101 3.9E-7 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily STK_18490 587884368a118c17f56c516fe49a0298 103 SUPERFAMILY SSF143011 32 98 2.35E-9 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily STK_25940 b3f751bad5ac4f42b31c5b08e8dc0a82 200 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 82 152 1.7E-7 T 23-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_25940 b3f751bad5ac4f42b31c5b08e8dc0a82 200 SUPERFAMILY SSF49503 56 168 2.95E-22 T 23-10-2018 IPR008972 Cupredoxin STK_25940 b3f751bad5ac4f42b31c5b08e8dc0a82 200 Gene3D G3DSA:2.60.40.2600 58 180 8.7E-24 T 23-10-2018 STK_18750 05f9f09cc9fddcb5ce8cb61ac2c001c6 279 SUPERFAMILY SSF46548 47 141 4.36E-16 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 STK_18750 05f9f09cc9fddcb5ce8cb61ac2c001c6 279 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 65 76 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_18750 05f9f09cc9fddcb5ce8cb61ac2c001c6 279 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 111 122 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_18750 05f9f09cc9fddcb5ce8cb61ac2c001c6 279 Pfam PF13534 4Fe-4S dicluster domain 65 123 4.4E-7 T 23-10-2018 STK_18750 05f9f09cc9fddcb5ce8cb61ac2c001c6 279 Gene3D G3DSA:1.10.1060.10 34 143 4.1E-9 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 STK_04210 40e87cb2ed7ba92a9b05c270a3d35dbd 243 Gene3D G3DSA:2.30.30.30 176 243 5.7E-14 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 STK_04210 40e87cb2ed7ba92a9b05c270a3d35dbd 243 Hamap MF_00485 30S ribosomal protein S4e [rps4e]. 2 242 39.238 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04210 40e87cb2ed7ba92a9b05c270a3d35dbd 243 SMART SM00363 37 102 1.2E-6 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04210 40e87cb2ed7ba92a9b05c270a3d35dbd 243 PIRSF PIRSF002116 1 242 6.0E-87 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04210 40e87cb2ed7ba92a9b05c270a3d35dbd 243 Gene3D G3DSA:3.10.290.40 1 112 4.2E-36 T 23-10-2018 STK_04210 40e87cb2ed7ba92a9b05c270a3d35dbd 243 SUPERFAMILY SSF55174 34 94 1.3E-9 T 23-10-2018 STK_04210 40e87cb2ed7ba92a9b05c270a3d35dbd 243 Pfam PF00900 Ribosomal family S4e 91 169 6.3E-23 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04210 40e87cb2ed7ba92a9b05c270a3d35dbd 243 Pfam PF01479 S4 domain 46 85 4.7E-11 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04210 40e87cb2ed7ba92a9b05c270a3d35dbd 243 Gene3D G3DSA:2.40.50.740 117 172 7.8E-18 T 23-10-2018 IPR038237 Ribosomal protein S4e, central domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04210 40e87cb2ed7ba92a9b05c270a3d35dbd 243 Pfam PF08071 RS4NT (NUC023) domain 3 33 5.5E-7 T 23-10-2018 IPR013843 Ribosomal protein S4e, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04210 40e87cb2ed7ba92a9b05c270a3d35dbd 243 ProDom PD002667 RIBOSOMAL RIBONUCLEOPROTEIN RNA-BINDING 40S S4 S4 S4E 30S ISOFORM X 82 170 2.0E-44 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_23180 06b78b1cb34658d332a7d93c97de0a8c 460 Pfam PF06508 Queuosine biosynthesis protein QueC 240 449 4.7E-62 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 STK_23180 06b78b1cb34658d332a7d93c97de0a8c 460 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 239 456 45.445 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 STK_23180 06b78b1cb34658d332a7d93c97de0a8c 460 SUPERFAMILY SSF52402 239 458 5.73E-51 T 23-10-2018 STK_23180 06b78b1cb34658d332a7d93c97de0a8c 460 Gene3D G3DSA:3.60.20.10 2 240 3.4E-32 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_23180 06b78b1cb34658d332a7d93c97de0a8c 460 SUPERFAMILY SSF56235 14 225 8.58E-26 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_23180 06b78b1cb34658d332a7d93c97de0a8c 460 Pfam PF13537 Glutamine amidotransferase domain 90 203 3.1E-16 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain STK_23180 06b78b1cb34658d332a7d93c97de0a8c 460 Gene3D G3DSA:3.40.50.620 241 451 2.6E-59 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_23180 06b78b1cb34658d332a7d93c97de0a8c 460 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 242 443 4.5E-48 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 STK_09110 3b13f019a8663b54b7b2baf7f087e188 476 Gene3D G3DSA:1.20.1250.20 12 227 3.4E-51 T 23-10-2018 STK_09110 3b13f019a8663b54b7b2baf7f087e188 476 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 13 453 1.9E-75 T 23-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 STK_09110 3b13f019a8663b54b7b2baf7f087e188 476 SUPERFAMILY SSF103473 10 453 1.7E-59 T 23-10-2018 IPR036259 MFS transporter superfamily STK_09110 3b13f019a8663b54b7b2baf7f087e188 476 ProSitePatterns PS00216 Sugar transport proteins signature 1. 319 335 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 STK_09110 3b13f019a8663b54b7b2baf7f087e188 476 Pfam PF00083 Sugar (and other) transporter 24 458 1.6E-82 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 STK_09110 3b13f019a8663b54b7b2baf7f087e188 476 PRINTS PR00171 Sugar transporter signature 266 276 1.7E-16 T 23-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 STK_09110 3b13f019a8663b54b7b2baf7f087e188 476 PRINTS PR00171 Sugar transporter signature 359 380 1.7E-16 T 23-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 STK_09110 3b13f019a8663b54b7b2baf7f087e188 476 PRINTS PR00171 Sugar transporter signature 382 394 1.7E-16 T 23-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 STK_09110 3b13f019a8663b54b7b2baf7f087e188 476 PRINTS PR00171 Sugar transporter signature 112 131 1.7E-16 T 23-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 STK_09110 3b13f019a8663b54b7b2baf7f087e188 476 PRINTS PR00171 Sugar transporter signature 31 41 1.7E-16 T 23-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 STK_09110 3b13f019a8663b54b7b2baf7f087e188 476 Gene3D G3DSA:1.20.1250.20 234 462 6.7E-45 T 23-10-2018 STK_09110 3b13f019a8663b54b7b2baf7f087e188 476 ProSitePatterns PS00217 Sugar transport proteins signature 2. 117 142 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 STK_13360 cbfc615d3ce00d8f20c0ac0495e4e467 312 SMART SM00729 59 286 0.002 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 STK_13360 cbfc615d3ce00d8f20c0ac0495e4e467 312 Pfam PF04055 Radical SAM superfamily 63 241 1.9E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_13360 cbfc615d3ce00d8f20c0ac0495e4e467 312 SUPERFAMILY SSF102114 64 268 1.31E-10 T 23-10-2018 STK_13360 cbfc615d3ce00d8f20c0ac0495e4e467 312 Gene3D G3DSA:3.80.30.30 148 297 1.3E-7 T 23-10-2018 STK_01270 9db16927474d8c42cd5d798a7fab14c9 347 PIRSF PIRSF037420 1 347 3.2E-84 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E STK_01270 9db16927474d8c42cd5d798a7fab14c9 347 Gene3D G3DSA:3.20.20.70 3 310 8.7E-41 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_01270 9db16927474d8c42cd5d798a7fab14c9 347 SMART SM00729 8 208 0.002 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 STK_01270 9db16927474d8c42cd5d798a7fab14c9 347 SUPERFAMILY SSF102114 6 326 8.76E-58 T 23-10-2018 STK_01270 9db16927474d8c42cd5d798a7fab14c9 347 Pfam PF13186 Iron-sulfur cluster-binding domain 266 318 7.4E-5 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain STK_01270 9db16927474d8c42cd5d798a7fab14c9 347 TIGRFAM TIGR04053 sam_11: radical SAM protein, BA_1875 family 2 347 3.4E-144 T 23-10-2018 IPR027634 Radical SAM protein, BA_1875 family STK_01270 9db16927474d8c42cd5d798a7fab14c9 347 Pfam PF04055 Radical SAM superfamily 13 156 1.1E-14 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_01270 9db16927474d8c42cd5d798a7fab14c9 347 Pfam PF13353 4Fe-4S single cluster domain 15 81 6.8E-6 T 23-10-2018 STK_12040 6bd9a9776c3533fc35868725a650cd71 247 Pfam PF09754 PAC2 family 20 226 2.9E-38 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 STK_12040 6bd9a9776c3533fc35868725a650cd71 247 Gene3D G3DSA:3.40.50.10900 1 241 2.0E-50 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily STK_12040 6bd9a9776c3533fc35868725a650cd71 247 SUPERFAMILY SSF159659 3 234 1.57E-43 T 23-10-2018 STK_07860 46849eb3d13e10450af00d27aa3c0d83 138 Gene3D G3DSA:1.20.120.580 4 135 9.3E-10 T 23-10-2018 IPR037038 Bsu32300-like superfamily STK_07860 46849eb3d13e10450af00d27aa3c0d83 138 SUPERFAMILY SSF81593 10 121 2.9E-6 T 23-10-2018 STK_07860 46849eb3d13e10450af00d27aa3c0d83 138 Pfam PF01934 Protein of unknown function DUF86 23 125 1.4E-18 T 23-10-2018 IPR008201 Protein of unknown function DUF86 STK_04770 28831c5e2d785543dd70bcfaad88f0b6 207 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 17 64 - T 23-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 STK_04770 28831c5e2d785543dd70bcfaad88f0b6 207 Pfam PF00227 Proteasome subunit 11 190 8.8E-51 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 STK_04770 28831c5e2d785543dd70bcfaad88f0b6 207 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 13 195 1.2E-70 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 STK_04770 28831c5e2d785543dd70bcfaad88f0b6 207 PRINTS PR00141 Proteasome component signature 141 152 1.4E-10 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 STK_04770 28831c5e2d785543dd70bcfaad88f0b6 207 PRINTS PR00141 Proteasome component signature 152 163 1.4E-10 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 STK_04770 28831c5e2d785543dd70bcfaad88f0b6 207 PRINTS PR00141 Proteasome component signature 21 36 1.4E-10 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 STK_04770 28831c5e2d785543dd70bcfaad88f0b6 207 PRINTS PR00141 Proteasome component signature 177 188 1.4E-10 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 STK_04770 28831c5e2d785543dd70bcfaad88f0b6 207 Gene3D G3DSA:3.60.20.10 1 205 6.8E-59 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_04770 28831c5e2d785543dd70bcfaad88f0b6 207 SUPERFAMILY SSF56235 6 198 2.85E-60 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_04770 28831c5e2d785543dd70bcfaad88f0b6 207 Hamap MF_02113_A Proteasome subunit beta [prcB]. 9 204 33.422 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 STK_19260 84398b3cfa85bb32fb878754f3e69213 353 Gene3D G3DSA:3.40.50.2000 5 180 4.0E-5 T 23-10-2018 STK_19260 84398b3cfa85bb32fb878754f3e69213 353 SUPERFAMILY SSF53756 96 351 4.31E-36 T 23-10-2018 STK_19260 84398b3cfa85bb32fb878754f3e69213 353 Pfam PF00534 Glycosyl transferases group 1 211 327 1.5E-15 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 STK_19260 84398b3cfa85bb32fb878754f3e69213 353 Gene3D G3DSA:3.40.50.2000 181 351 1.2E-19 T 23-10-2018 STK_04460 c57a29853e311e746d2dd28c2eae0fcf 235 Pfam PF00227 Proteasome subunit 26 211 3.5E-58 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 STK_04460 c57a29853e311e746d2dd28c2eae0fcf 235 SUPERFAMILY SSF56235 1 234 2.04E-75 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_04460 c57a29853e311e746d2dd28c2eae0fcf 235 ProSitePatterns PS00388 Proteasome alpha-type subunits signature. 3 25 - T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 STK_04460 c57a29853e311e746d2dd28c2eae0fcf 235 SMART SM00948 3 25 7.3E-10 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 STK_04460 c57a29853e311e746d2dd28c2eae0fcf 235 Gene3D G3DSA:3.60.20.10 1 235 2.1E-78 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_04460 c57a29853e311e746d2dd28c2eae0fcf 235 TIGRFAM TIGR03633 arc_protsome_A: proteasome endopeptidase complex, archaeal, alpha subunit 1 233 5.7E-103 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 STK_04460 c57a29853e311e746d2dd28c2eae0fcf 235 Hamap MF_00289_A Proteasome subunit alpha [prcA]. 1 232 43.257 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 STK_04460 c57a29853e311e746d2dd28c2eae0fcf 235 Pfam PF10584 Proteasome subunit A N-terminal signature 3 25 5.0E-13 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 STK_09944 61f1584ca1caacf4315ebe2b51c53718 79 Pfam PF13173 AAA domain 1 62 4.4E-17 T 23-10-2018 STK_09944 61f1584ca1caacf4315ebe2b51c53718 79 SUPERFAMILY SSF52540 1 69 1.95E-6 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_03450 dcea1cf7037e9f5612ac35a36aa879c8 233 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 148 4.2E-16 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain STK_03450 dcea1cf7037e9f5612ac35a36aa879c8 233 SUPERFAMILY SSF54534 3 152 6.87E-40 T 23-10-2018 STK_03450 dcea1cf7037e9f5612ac35a36aa879c8 233 Gene3D G3DSA:2.40.10.330 90 134 8.8E-51 T 23-10-2018 STK_03450 dcea1cf7037e9f5612ac35a36aa879c8 233 Gene3D G3DSA:3.30.70.2210 153 231 1.7E-5 T 23-10-2018 STK_03450 dcea1cf7037e9f5612ac35a36aa879c8 233 Gene3D G3DSA:3.10.50.40 5 148 8.8E-51 T 23-10-2018 STK_03290 b449b6505955952bdce9e9cb57d2e25b 176 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 95 162 4.5E-10 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 STK_03290 b449b6505955952bdce9e9cb57d2e25b 176 SMART SM00359 92 166 2.4E-11 T 23-10-2018 IPR002478 PUA domain GO:0003723 STK_03290 b449b6505955952bdce9e9cb57d2e25b 176 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 16 90 2.3E-18 T 23-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 STK_03290 b449b6505955952bdce9e9cb57d2e25b 176 SUPERFAMILY SSF88802 9 88 3.33E-13 T 23-10-2018 STK_03290 b449b6505955952bdce9e9cb57d2e25b 176 SUPERFAMILY SSF88697 92 165 3.73E-19 T 23-10-2018 IPR015947 PUA-like superfamily STK_03290 b449b6505955952bdce9e9cb57d2e25b 176 Pfam PF01472 PUA domain 93 164 4.1E-18 T 23-10-2018 IPR002478 PUA domain GO:0003723 STK_03290 b449b6505955952bdce9e9cb57d2e25b 176 Gene3D G3DSA:2.30.130.10 89 166 3.8E-30 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 STK_03290 b449b6505955952bdce9e9cb57d2e25b 176 Gene3D G3DSA:3.10.450.90 9 87 4.1E-11 T 23-10-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 STK_14720 e92f9e1dcc2288c6c67b619962ff16a2 101 Pfam PF02150 RNA polymerases M/15 Kd subunit 1 34 5.7E-10 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 STK_14720 e92f9e1dcc2288c6c67b619962ff16a2 101 SMART SM00661 2 57 2.1E-14 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 STK_18410 b7928d2cdc40889b475eb0f827f1d243 296 SMART SM00028 255 288 21.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 STK_18410 b7928d2cdc40889b475eb0f827f1d243 296 SMART SM00028 53 86 110.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 STK_18410 b7928d2cdc40889b475eb0f827f1d243 296 SMART SM00028 155 188 13.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 STK_18410 b7928d2cdc40889b475eb0f827f1d243 296 SMART SM00028 121 154 0.074 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 STK_18410 b7928d2cdc40889b475eb0f827f1d243 296 SMART SM00028 87 120 0.0073 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 STK_18410 b7928d2cdc40889b475eb0f827f1d243 296 SMART SM00028 189 222 14.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 STK_18410 b7928d2cdc40889b475eb0f827f1d243 296 SUPERFAMILY SSF48452 192 287 4.17E-8 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 STK_18410 b7928d2cdc40889b475eb0f827f1d243 296 Pfam PF13432 Tetratricopeptide repeat 195 241 2.1E-4 T 23-10-2018 STK_18410 b7928d2cdc40889b475eb0f827f1d243 296 Gene3D G3DSA:1.25.40.10 161 222 1.6E-10 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 STK_18410 b7928d2cdc40889b475eb0f827f1d243 296 Gene3D G3DSA:1.25.40.10 84 160 5.4E-13 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 STK_18410 b7928d2cdc40889b475eb0f827f1d243 296 Gene3D G3DSA:1.25.40.10 223 296 2.9E-6 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 STK_18410 b7928d2cdc40889b475eb0f827f1d243 296 Pfam PF13181 Tetratricopeptide repeat 123 154 3.4E-4 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 STK_18410 b7928d2cdc40889b475eb0f827f1d243 296 Pfam PF13181 Tetratricopeptide repeat 256 287 0.018 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 STK_18410 b7928d2cdc40889b475eb0f827f1d243 296 Pfam PF13181 Tetratricopeptide repeat 89 116 0.0023 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 STK_18410 b7928d2cdc40889b475eb0f827f1d243 296 SUPERFAMILY SSF48452 12 220 3.14E-31 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 STK_18410 b7928d2cdc40889b475eb0f827f1d243 296 Gene3D G3DSA:1.25.40.10 4 83 2.2E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 STK_03500 a8c5c0eb55c6adc4213e8b784856b476 100 Gene3D G3DSA:3.30.780.10 21 99 4.8E-31 T 23-10-2018 STK_03500 a8c5c0eb55c6adc4213e8b784856b476 100 Hamap MF_00604 Protein translation factor SUI1 homolog. 5 94 25.886 T 23-10-2018 IPR022851 Translation factor SUI1 homolog, archaea STK_03500 a8c5c0eb55c6adc4213e8b784856b476 100 SUPERFAMILY SSF55159 17 98 2.35E-26 T 23-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 STK_03500 a8c5c0eb55c6adc4213e8b784856b476 100 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 6 96 1.3E-36 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 STK_03500 a8c5c0eb55c6adc4213e8b784856b476 100 PIRSF PIRSF037511 4 98 1.9E-27 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 STK_03500 a8c5c0eb55c6adc4213e8b784856b476 100 Pfam PF01253 Translation initiation factor SUI1 22 92 9.3E-23 T 23-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 STK_14210 f8905c7b754229632817470d92a90f19 395 SUPERFAMILY SSF109604 1 391 1.96E-77 T 23-10-2018 STK_14210 f8905c7b754229632817470d92a90f19 395 Gene3D G3DSA:1.10.3210.10 1 248 4.7E-72 T 23-10-2018 STK_14210 f8905c7b754229632817470d92a90f19 395 SMART SM00471 46 174 7.2E-4 T 23-10-2018 IPR003607 HD/PDEase domain STK_14210 f8905c7b754229632817470d92a90f19 395 Pfam PF01966 HD domain 50 166 6.3E-6 T 23-10-2018 IPR006674 HD domain STK_00660 6607e84f12fdb16f17f29d2062c082d1 389 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 23-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 STK_00660 6607e84f12fdb16f17f29d2062c082d1 389 SUPERFAMILY SSF47203 229 387 1.77E-35 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 STK_00660 6607e84f12fdb16f17f29d2062c082d1 389 SUPERFAMILY SSF56645 7 243 3.27E-49 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 STK_00660 6607e84f12fdb16f17f29d2062c082d1 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 218 2.0E-19 T 23-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 STK_00660 6607e84f12fdb16f17f29d2062c082d1 389 Gene3D G3DSA:1.20.140.10 236 388 1.8E-30 T 23-10-2018 STK_00660 6607e84f12fdb16f17f29d2062c082d1 389 Gene3D G3DSA:1.10.540.10 5 119 2.6E-11 T 23-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 STK_00660 6607e84f12fdb16f17f29d2062c082d1 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 367 4.9E-27 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 STK_00660 6607e84f12fdb16f17f29d2062c082d1 389 Gene3D G3DSA:2.40.110.10 121 235 5.7E-30 T 23-10-2018 STK_00660 6607e84f12fdb16f17f29d2062c082d1 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 117 1.5E-7 T 23-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 STK_16960 1cf9540549f742c9a39af13a568fec6e 175 Gene3D G3DSA:3.40.50.150 19 173 9.6E-17 T 23-10-2018 STK_16960 1cf9540549f742c9a39af13a568fec6e 175 Pfam PF08241 Methyltransferase domain 39 136 2.9E-9 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 STK_16960 1cf9540549f742c9a39af13a568fec6e 175 SUPERFAMILY SSF53335 24 164 3.25E-15 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_03860 c717a3ab5f6325320dfdcce614b9f509 322 Gene3D G3DSA:3.20.20.210 1 320 5.5E-39 T 23-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 STK_03860 c717a3ab5f6325320dfdcce614b9f509 322 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 81 266 4.2E-20 T 23-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 STK_03860 c717a3ab5f6325320dfdcce614b9f509 322 SUPERFAMILY SSF51726 5 317 2.09E-42 T 23-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 STK_09370 3cf388b20a3b78624fa1c8204497154f 227 SUPERFAMILY SSF51556 1 227 3.57E-49 T 23-10-2018 IPR032466 Metal-dependent hydrolase STK_09370 3cf388b20a3b78624fa1c8204497154f 227 PIRSF PIRSF005902 1 227 1.3E-43 T 23-10-2018 IPR001130 TatD family GO:0016788 STK_09370 3cf388b20a3b78624fa1c8204497154f 227 Pfam PF01026 TatD related DNase 14 226 1.6E-38 T 23-10-2018 IPR001130 TatD family GO:0016788 STK_09370 3cf388b20a3b78624fa1c8204497154f 227 Gene3D G3DSA:3.20.20.140 1 227 3.2E-51 T 23-10-2018 STK_24330 7efd49268a1ef1f55e27ed83534406cf 304 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 197 269 3.1E-24 T 23-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal STK_24330 7efd49268a1ef1f55e27ed83534406cf 304 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 9 291 9.2E-133 T 23-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate STK_24330 7efd49268a1ef1f55e27ed83534406cf 304 Gene3D G3DSA:3.40.50.970 20 197 9.5E-23 T 23-10-2018 STK_24330 7efd49268a1ef1f55e27ed83534406cf 304 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 44 193 1.6E-30 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 STK_24330 7efd49268a1ef1f55e27ed83534406cf 304 SUPERFAMILY SSF52518 10 285 1.59E-76 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold STK_01180 68fadc5b2081f0f9681799000c373fe7 232 Gene3D G3DSA:3.90.850.10 2 229 6.8E-24 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 STK_01180 68fadc5b2081f0f9681799000c373fe7 232 SUPERFAMILY SSF56529 2 221 2.75E-25 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 STK_18110 e5c730b18cc80a6527fb39d26bbcd06f 308 Gene3D G3DSA:3.90.110.10 143 302 8.6E-28 T 23-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 STK_18110 e5c730b18cc80a6527fb39d26bbcd06f 308 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 2 133 1.0E-31 T 23-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 STK_18110 e5c730b18cc80a6527fb39d26bbcd06f 308 SUPERFAMILY SSF51735 3 133 1.32E-36 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_18110 e5c730b18cc80a6527fb39d26bbcd06f 308 SUPERFAMILY SSF56327 140 296 7.6E-31 T 23-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 STK_18110 e5c730b18cc80a6527fb39d26bbcd06f 308 PRINTS PR00086 L-lactate dehydrogenase signature 137 155 3.6E-15 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 STK_18110 e5c730b18cc80a6527fb39d26bbcd06f 308 PRINTS PR00086 L-lactate dehydrogenase signature 28 52 3.6E-15 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 STK_18110 e5c730b18cc80a6527fb39d26bbcd06f 308 PRINTS PR00086 L-lactate dehydrogenase signature 167 180 3.6E-15 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 STK_18110 e5c730b18cc80a6527fb39d26bbcd06f 308 PRINTS PR00086 L-lactate dehydrogenase signature 3 27 3.6E-15 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 STK_18110 e5c730b18cc80a6527fb39d26bbcd06f 308 Gene3D G3DSA:3.40.50.720 1 141 5.1E-36 T 23-10-2018 STK_18110 e5c730b18cc80a6527fb39d26bbcd06f 308 PIRSF PIRSF000102 1 305 1.8E-80 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 STK_03700 49959f7b21485c4def7f1ca3e29ee5cf 257 SUPERFAMILY SSF53335 1 251 2.87E-71 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_03700 49959f7b21485c4def7f1ca3e29ee5cf 257 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 58 239 7.5E-33 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 STK_03700 49959f7b21485c4def7f1ca3e29ee5cf 257 Gene3D G3DSA:3.40.50.150 64 256 2.3E-67 T 23-10-2018 STK_03700 49959f7b21485c4def7f1ca3e29ee5cf 257 Gene3D G3DSA:3.10.330.20 1 62 2.5E-17 T 23-10-2018 STK_03700 49959f7b21485c4def7f1ca3e29ee5cf 257 PIRSF PIRSF017269 1 257 2.2E-83 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 STK_14780 ebe92b55240d08143b89e7a21654e9db 389 SUPERFAMILY SSF51338 124 375 9.87E-8 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_14780 ebe92b55240d08143b89e7a21654e9db 389 ProSitePatterns PS00482 Dihydroorotase signature 1. 49 57 - T 23-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_14780 ebe92b55240d08143b89e7a21654e9db 389 Pfam PF01979 Amidohydrolase family 188 365 2.3E-7 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 STK_14780 ebe92b55240d08143b89e7a21654e9db 389 ProSitePatterns PS00483 Dihydroorotase signature 2. 252 263 - T 23-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_14780 ebe92b55240d08143b89e7a21654e9db 389 Hamap MF_00220_A Dihydroorotase [pyrC]. 1 373 58.019 T 23-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 STK_14780 ebe92b55240d08143b89e7a21654e9db 389 SUPERFAMILY SSF51556 48 316 4.36E-57 T 23-10-2018 IPR032466 Metal-dependent hydrolase STK_14780 ebe92b55240d08143b89e7a21654e9db 389 Gene3D G3DSA:3.20.20.140 36 385 2.0E-64 T 23-10-2018 STK_09105 85776302bd89d6f016233716905c5b40 107 Pfam PF05942 Archaeal PaREP1/PaREP8 family 1 104 1.8E-28 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_09105 85776302bd89d6f016233716905c5b40 107 Gene3D G3DSA:1.20.120.330 1 107 2.1E-38 T 23-10-2018 STK_15960 173fe3aefbdfbee6fb3e5eccf3ba79cf 284 Pfam PF04909 Amidohydrolase 4 278 2.8E-27 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 STK_15960 173fe3aefbdfbee6fb3e5eccf3ba79cf 284 SUPERFAMILY SSF51556 4 278 1.83E-39 T 23-10-2018 IPR032466 Metal-dependent hydrolase STK_15960 173fe3aefbdfbee6fb3e5eccf3ba79cf 284 Gene3D G3DSA:3.20.20.140 1 279 8.9E-46 T 23-10-2018 STK_25610 18f01f01940caa949489a773eb3c0b3d 370 Pfam PF13378 Enolase C-terminal domain-like 150 342 2.5E-41 T 23-10-2018 IPR029065 Enolase C-terminal domain-like STK_25610 18f01f01940caa949489a773eb3c0b3d 370 Gene3D G3DSA:3.20.20.120 122 342 5.5E-52 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily STK_25610 18f01f01940caa949489a773eb3c0b3d 370 SMART SM00922 141 236 2.1E-15 T 23-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal STK_25610 18f01f01940caa949489a773eb3c0b3d 370 Gene3D G3DSA:3.30.390.10 2 121 8.7E-8 T 23-10-2018 IPR029017 Enolase-like, N-terminal STK_25610 18f01f01940caa949489a773eb3c0b3d 370 SUPERFAMILY SSF51604 111 351 1.31E-51 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily STK_25610 18f01f01940caa949489a773eb3c0b3d 370 SUPERFAMILY SSF54826 8 127 2.69E-12 T 23-10-2018 STK_21940 68723f3ddc11798fceff22a706aad4e2 630 Gene3D G3DSA:2.60.40.1120 364 440 3.7E-7 T 23-10-2018 STK_21940 68723f3ddc11798fceff22a706aad4e2 630 SUPERFAMILY SSF49464 366 440 1.86E-7 T 23-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily STK_12680 03d7647af0ee8373fb4b87b6b4ec5ed3 294 Gene3D G3DSA:1.10.260.40 116 231 2.8E-10 T 23-10-2018 STK_12680 03d7647af0ee8373fb4b87b6b4ec5ed3 294 SUPERFAMILY SSF47413 120 173 3.75E-10 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 STK_12680 03d7647af0ee8373fb4b87b6b4ec5ed3 294 Hamap MF_00584 Putative HTH-type transcriptional regulatory protein . 1 294 22.104 T 23-10-2018 IPR020886 Transcription regulator HTH, Cro/C1-type DNA-binding GO:0003700|GO:0006355 STK_12680 03d7647af0ee8373fb4b87b6b4ec5ed3 294 SMART SM00530 122 177 2.5E-8 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 STK_12680 03d7647af0ee8373fb4b87b6b4ec5ed3 294 Pfam PF01381 Helix-turn-helix 123 171 4.3E-10 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 STK_03050 c2ce57747f00d1ca11b3b26986f56073 398 Gene3D G3DSA:1.10.10.10 295 397 4.7E-32 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_03050 c2ce57747f00d1ca11b3b26986f56073 398 Gene3D G3DSA:1.10.8.60 21 287 1.1E-107 T 23-10-2018 STK_03050 c2ce57747f00d1ca11b3b26986f56073 398 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 17 374 7.1E-146 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea STK_03050 c2ce57747f00d1ca11b3b26986f56073 398 Pfam PF13401 AAA domain 56 178 1.7E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_03050 c2ce57747f00d1ca11b3b26986f56073 398 SUPERFAMILY SSF52540 17 280 6.98E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_03050 c2ce57747f00d1ca11b3b26986f56073 398 SMART SM00382 55 209 2.3E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_03050 c2ce57747f00d1ca11b3b26986f56073 398 Gene3D G3DSA:3.40.50.300 33 207 1.1E-107 T 23-10-2018 STK_03050 c2ce57747f00d1ca11b3b26986f56073 398 SMART SM01074 303 385 4.5E-34 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 STK_03050 c2ce57747f00d1ca11b3b26986f56073 398 SUPERFAMILY SSF46785 287 388 5.03E-29 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_03050 c2ce57747f00d1ca11b3b26986f56073 398 Hamap MF_01407 ORC1-type DNA replication protein. 10 385 33.752 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea STK_03050 c2ce57747f00d1ca11b3b26986f56073 398 Pfam PF09079 CDC6, C terminal winged helix domain 303 384 2.3E-24 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 STK_21360 730aea1d909f8eb1bfef0405dce32283 248 Gene3D G3DSA:2.60.200.30 96 229 4.5E-39 T 23-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 STK_21360 730aea1d909f8eb1bfef0405dce32283 248 Hamap MF_00361 NAD kinase [nadK]. 1 248 20.739 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 STK_21360 730aea1d909f8eb1bfef0405dce32283 248 Pfam PF01513 ATP-NAD kinase 30 236 4.3E-25 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 STK_21360 730aea1d909f8eb1bfef0405dce32283 248 SUPERFAMILY SSF111331 20 237 1.1E-42 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily STK_21360 730aea1d909f8eb1bfef0405dce32283 248 Gene3D G3DSA:3.40.50.10330 33 237 4.5E-39 T 23-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 STK_11680 e6e138bf8ed3d4c123a606a936043ee2 854 Pfam PF07676 WD40-like Beta Propeller Repeat 285 314 9.5E-7 T 23-10-2018 IPR011659 WD40-like Beta Propeller STK_11680 e6e138bf8ed3d4c123a606a936043ee2 854 SUPERFAMILY SSF52096 475 851 2.49E-72 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily STK_11680 e6e138bf8ed3d4c123a606a936043ee2 854 Gene3D G3DSA:2.30.42.10 555 646 6.0E-12 T 23-10-2018 STK_11680 e6e138bf8ed3d4c123a606a936043ee2 854 Gene3D G3DSA:3.90.226.10 647 854 1.3E-67 T 23-10-2018 STK_11680 e6e138bf8ed3d4c123a606a936043ee2 854 Gene3D G3DSA:2.130.10.10 128 459 6.4E-91 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 STK_11680 e6e138bf8ed3d4c123a606a936043ee2 854 SUPERFAMILY SSF82171 41 313 7.45E-26 T 23-10-2018 STK_11680 e6e138bf8ed3d4c123a606a936043ee2 854 Pfam PF03572 Peptidase family S41 669 824 5.9E-24 T 23-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 STK_11680 e6e138bf8ed3d4c123a606a936043ee2 854 Gene3D G3DSA:3.30.750.44 476 544 7.6E-28 T 23-10-2018 STK_11680 e6e138bf8ed3d4c123a606a936043ee2 854 Gene3D G3DSA:2.120.10.60 11 109 1.0E-28 T 23-10-2018 STK_11680 e6e138bf8ed3d4c123a606a936043ee2 854 Pfam PF14684 Tricorn protease C1 domain 478 543 1.1E-24 T 23-10-2018 IPR028204 Tricorn protease C1 domain STK_11680 e6e138bf8ed3d4c123a606a936043ee2 854 SMART SM00245 635 825 5.9E-45 T 23-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 STK_11680 e6e138bf8ed3d4c123a606a936043ee2 854 SUPERFAMILY SSF50156 556 643 5.0E-15 T 23-10-2018 IPR036034 PDZ superfamily GO:0005515 STK_11680 e6e138bf8ed3d4c123a606a936043ee2 854 Pfam PF14685 Tricorn protease PDZ domain 556 640 2.3E-24 T 23-10-2018 IPR029414 Tricorn protease, PDZ domain STK_17370 c5d28f386c40b31222e7b6f307a3fb46 536 Gene3D G3DSA:3.40.50.1820 296 535 1.6E-56 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold STK_17370 c5d28f386c40b31222e7b6f307a3fb46 536 SUPERFAMILY SSF53474 297 535 3.22E-52 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold STK_17370 c5d28f386c40b31222e7b6f307a3fb46 536 Pfam PF00326 Prolyl oligopeptidase family 338 534 1.6E-42 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 STK_17370 c5d28f386c40b31222e7b6f307a3fb46 536 SUPERFAMILY SSF82171 16 298 3.22E-16 T 23-10-2018 STK_11580 319bb93678f3af3736ddf1054a10f51d 136 SUPERFAMILY SSF143422 2 128 1.57E-49 T 23-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 STK_11580 319bb93678f3af3736ddf1054a10f51d 136 Pfam PF01797 Transposase IS200 like 11 128 9.0E-43 T 23-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 STK_11580 319bb93678f3af3736ddf1054a10f51d 136 SMART SM01321 10 128 8.2E-47 T 23-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 STK_11580 319bb93678f3af3736ddf1054a10f51d 136 Gene3D G3DSA:3.30.70.1290 1 136 5.9E-52 T 23-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 STK_20340 b0d508be4aa69c73ff222bb799922694 376 SUPERFAMILY SSF53850 58 341 1.13E-29 T 23-10-2018 STK_20340 b0d508be4aa69c73ff222bb799922694 376 Gene3D G3DSA:3.40.190.10 139 306 1.4E-31 T 23-10-2018 STK_20340 b0d508be4aa69c73ff222bb799922694 376 Gene3D G3DSA:3.40.190.10 62 329 1.4E-31 T 23-10-2018 STK_20340 b0d508be4aa69c73ff222bb799922694 376 Pfam PF13531 Bacterial extracellular solute-binding protein 63 327 6.8E-27 T 23-10-2018 STK_02750 591e91b5a3281098d6c9792a101e9c96 392 Pfam PF04998 RNA polymerase Rpb1, domain 5 53 337 6.4E-58 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_02750 591e91b5a3281098d6c9792a101e9c96 392 SUPERFAMILY SSF64484 15 390 1.72E-107 T 23-10-2018 STK_02750 591e91b5a3281098d6c9792a101e9c96 392 TIGRFAM TIGR02389 RNA_pol_rpoA2: DNA-directed RNA polymerase, subunit A'' 21 388 8.6E-162 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_02750 591e91b5a3281098d6c9792a101e9c96 392 Gene3D G3DSA:1.10.150.390 338 383 3.7E-23 T 23-10-2018 STK_02750 591e91b5a3281098d6c9792a101e9c96 392 Hamap MF_00411 DNA-directed RNA polymerase subunit A'' [rpoA2]. 6 390 42.026 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 STK_07900 5dff381cd31e62b9315e993516785e8b 109 Gene3D G3DSA:3.30.460.10 16 109 4.4E-29 T 23-10-2018 STK_07900 5dff381cd31e62b9315e993516785e8b 109 SUPERFAMILY SSF81301 19 107 1.57E-19 T 23-10-2018 STK_07900 5dff381cd31e62b9315e993516785e8b 109 Pfam PF01909 Nucleotidyltransferase domain 20 100 3.5E-14 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_17870 1514e1dcd3711e3a9b0ca0f62ccd0b1a 301 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 47 203 1.8E-24 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 STK_17870 1514e1dcd3711e3a9b0ca0f62ccd0b1a 301 Gene3D G3DSA:3.40.50.970 5 93 3.3E-8 T 23-10-2018 STK_17870 1514e1dcd3711e3a9b0ca0f62ccd0b1a 301 Gene3D G3DSA:3.40.50.970 94 298 4.5E-67 T 23-10-2018 STK_17870 1514e1dcd3711e3a9b0ca0f62ccd0b1a 301 SUPERFAMILY SSF52518 11 295 3.77E-81 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold STK_07280 e1dd58608ad867acc7881dac074eb261 386 Pfam PF00999 Sodium/hydrogen exchanger family 12 380 4.5E-45 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 STK_07280 e1dd58608ad867acc7881dac074eb261 386 Gene3D G3DSA:1.20.1530.20 6 385 3.3E-64 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily STK_16800 975a90a9cee96e43c94849b6615efd8f 540 Pfam PF00136 DNA polymerase family B 238 368 1.0E-11 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 STK_16800 975a90a9cee96e43c94849b6615efd8f 540 Gene3D G3DSA:3.90.1600.10 245 410 5.4E-44 T 23-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 STK_16800 975a90a9cee96e43c94849b6615efd8f 540 SMART SM00486 24 385 1.4E-20 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 STK_16800 975a90a9cee96e43c94849b6615efd8f 540 Gene3D G3DSA:1.10.287.690 294 340 5.4E-44 T 23-10-2018 STK_16800 975a90a9cee96e43c94849b6615efd8f 540 SUPERFAMILY SSF56672 207 496 8.34E-57 T 23-10-2018 STK_22400 cb6ba54f33d1655d2a4e066d5e99bac9 494 Gene3D G3DSA:3.40.50.300 2 318 2.0E-29 T 23-10-2018 STK_22400 cb6ba54f33d1655d2a4e066d5e99bac9 494 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 25 286 4.8E-19 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_22400 cb6ba54f33d1655d2a4e066d5e99bac9 494 SUPERFAMILY SSF52540 2 313 1.61E-26 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_04410 c6199e4d2fd936e7fa793366262cbd6a 176 Hamap MF_00699 Probable Brix domain-containing ribosomal biogenesis protein. 8 172 27.329 T 23-10-2018 IPR023548 Probable Brix domain-containing ribosomal biogenesis protein STK_04410 c6199e4d2fd936e7fa793366262cbd6a 176 SUPERFAMILY SSF52954 7 169 4.9E-30 T 23-10-2018 STK_04410 c6199e4d2fd936e7fa793366262cbd6a 176 SMART SM00879 9 171 1.6E-13 T 23-10-2018 IPR007109 Brix domain STK_04410 c6199e4d2fd936e7fa793366262cbd6a 176 Gene3D G3DSA:3.40.50.10480 6 167 1.6E-27 T 23-10-2018 STK_23850 a1d3c40f45b043bca775467195b5eb9b 305 Gene3D G3DSA:1.25.40.10 142 303 7.7E-9 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 STK_23850 a1d3c40f45b043bca775467195b5eb9b 305 SUPERFAMILY SSF48452 37 167 5.48E-15 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 STK_23850 a1d3c40f45b043bca775467195b5eb9b 305 SMART SM00028 76 109 420.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 STK_23850 a1d3c40f45b043bca775467195b5eb9b 305 SMART SM00028 267 300 99.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 STK_23850 a1d3c40f45b043bca775467195b5eb9b 305 SMART SM00028 39 72 2.5E-5 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 STK_23850 a1d3c40f45b043bca775467195b5eb9b 305 Gene3D G3DSA:1.25.40.10 2 141 1.7E-16 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 STK_23850 a1d3c40f45b043bca775467195b5eb9b 305 Pfam PF12895 Anaphase-promoting complex, cyclosome, subunit 3 52 137 1.2E-14 T 23-10-2018 STK_15470 36a6a9ec21828f4e6904df74d07d4dfa 260 Gene3D G3DSA:3.30.2010.10 53 140 1.4E-16 T 23-10-2018 STK_15470 36a6a9ec21828f4e6904df74d07d4dfa 260 Pfam PF01435 Peptidase family M48 61 255 2.8E-20 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 STK_22470 5a57c0359224360d4d0ac559ce498537 440 SUPERFAMILY SSF51905 4 194 7.56E-35 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_22470 5a57c0359224360d4d0ac559ce498537 440 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 299 3.3E-48 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 STK_22470 5a57c0359224360d4d0ac559ce498537 440 Gene3D G3DSA:3.50.50.60 113 432 5.2E-131 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_22470 5a57c0359224360d4d0ac559ce498537 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.2E-29 T 23-10-2018 STK_22470 5a57c0359224360d4d0ac559ce498537 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 1.2E-29 T 23-10-2018 STK_22470 5a57c0359224360d4d0ac559ce498537 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 229 245 1.2E-29 T 23-10-2018 STK_22470 5a57c0359224360d4d0ac559ce498537 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 1.2E-29 T 23-10-2018 STK_22470 5a57c0359224360d4d0ac559ce498537 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 277 1.2E-29 T 23-10-2018 STK_22470 5a57c0359224360d4d0ac559ce498537 440 Gene3D G3DSA:3.50.50.60 4 333 5.2E-131 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_22470 5a57c0359224360d4d0ac559ce498537 440 SUPERFAMILY SSF51905 149 313 7.62E-28 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_22470 5a57c0359224360d4d0ac559ce498537 440 SUPERFAMILY SSF55424 316 438 3.78E-30 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 STK_22470 5a57c0359224360d4d0ac559ce498537 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 3.9E-16 T 23-10-2018 STK_22470 5a57c0359224360d4d0ac559ce498537 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 230 244 3.9E-16 T 23-10-2018 STK_22470 5a57c0359224360d4d0ac559ce498537 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 148 173 3.9E-16 T 23-10-2018 STK_22470 5a57c0359224360d4d0ac559ce498537 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 270 277 3.9E-16 T 23-10-2018 STK_22470 5a57c0359224360d4d0ac559ce498537 440 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 323 424 7.8E-17 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 STK_07990 f99c34f48cae9ab8eab53c6e6026c477 106 SUPERFAMILY SSF81301 5 85 4.21E-14 T 23-10-2018 STK_07990 f99c34f48cae9ab8eab53c6e6026c477 106 Pfam PF01909 Nucleotidyltransferase domain 14 90 4.0E-11 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_07990 f99c34f48cae9ab8eab53c6e6026c477 106 Gene3D G3DSA:3.30.460.10 3 102 2.3E-12 T 23-10-2018 STK_25815 603d17c52351960377d73b50ae709722 71 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 1 43 5.1E-19 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_25815 603d17c52351960377d73b50ae709722 71 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 2 44 4.8E-10 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_25815 603d17c52351960377d73b50ae709722 71 SUPERFAMILY SSF89447 2 42 2.09E-10 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily STK_25815 603d17c52351960377d73b50ae709722 71 SMART SM00966 2 48 1.0E-11 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_25815 603d17c52351960377d73b50ae709722 71 Gene3D G3DSA:2.10.260.10 1 40 1.2E-12 T 23-10-2018 STK_11240 adfc7d648d6c450569109f965cfd7422 571 Pfam PF00723 Glycosyl hydrolases family 15 201 512 8.6E-49 T 23-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 STK_11240 adfc7d648d6c450569109f965cfd7422 571 SUPERFAMILY SSF48208 191 563 7.37E-86 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 STK_11240 adfc7d648d6c450569109f965cfd7422 571 Gene3D G3DSA:1.50.10.10 202 570 4.2E-81 T 23-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 STK_24290 5b5279b1caa6139c55d40ad822dc4f30 127 Pfam PF05942 Archaeal PaREP1/PaREP8 family 15 93 1.0E-18 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_24290 5b5279b1caa6139c55d40ad822dc4f30 127 Gene3D G3DSA:1.20.120.330 10 125 1.1E-28 T 23-10-2018 STK_26200 5be2d67d85afac8c6566c335b340d5c8 220 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 95 183 1.6E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 STK_26200 5be2d67d85afac8c6566c335b340d5c8 220 Gene3D G3DSA:1.10.150.660 17 93 5.7E-83 T 23-10-2018 STK_26200 5be2d67d85afac8c6566c335b340d5c8 220 Gene3D G3DSA:3.40.50.1000 6 211 5.7E-83 T 23-10-2018 IPR023214 HAD superfamily STK_26200 5be2d67d85afac8c6566c335b340d5c8 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 189 8.5E-15 T 23-10-2018 STK_26200 5be2d67d85afac8c6566c335b340d5c8 220 SUPERFAMILY SSF56784 2 217 4.93E-31 T 23-10-2018 IPR036412 HAD-like superfamily STK_01850 ed8df20ba4970c9af55b0f9ed4797392 294 Gene3D G3DSA:3.90.550.10 2 192 1.0E-15 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_01850 ed8df20ba4970c9af55b0f9ed4797392 294 Pfam PF00535 Glycosyl transferase family 2 13 127 2.3E-8 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 STK_01850 ed8df20ba4970c9af55b0f9ed4797392 294 SUPERFAMILY SSF53448 3 259 9.14E-23 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_00020 28df4aaf3471457f5b076fe682dc1e7d 579 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 387 411 5.1E-33 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 STK_00020 28df4aaf3471457f5b076fe682dc1e7d 579 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 441 461 5.1E-33 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 STK_00020 28df4aaf3471457f5b076fe682dc1e7d 579 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 415 434 5.1E-33 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 STK_00020 28df4aaf3471457f5b076fe682dc1e7d 579 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 513 535 5.1E-33 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 STK_00020 28df4aaf3471457f5b076fe682dc1e7d 579 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 361 379 5.1E-33 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 STK_00020 28df4aaf3471457f5b076fe682dc1e7d 579 Gene3D G3DSA:3.40.50.1820 308 579 5.8E-60 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold STK_00020 28df4aaf3471457f5b076fe682dc1e7d 579 SUPERFAMILY SSF50993 1 48 1.83E-5 T 23-10-2018 STK_00020 28df4aaf3471457f5b076fe682dc1e7d 579 Pfam PF00326 Prolyl oligopeptidase family 377 578 3.3E-44 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 STK_00020 28df4aaf3471457f5b076fe682dc1e7d 579 SUPERFAMILY SSF53474 339 578 2.47E-42 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold STK_24620 d61594a6144b3555ae9cfdfb8174b7c7 372 Pfam PF07690 Major Facilitator Superfamily 13 336 3.3E-38 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_24620 d61594a6144b3555ae9cfdfb8174b7c7 372 Gene3D G3DSA:1.20.1250.20 4 188 4.6E-27 T 23-10-2018 STK_24620 d61594a6144b3555ae9cfdfb8174b7c7 372 SUPERFAMILY SSF103473 4 370 9.16E-50 T 23-10-2018 IPR036259 MFS transporter superfamily STK_24620 d61594a6144b3555ae9cfdfb8174b7c7 372 Gene3D G3DSA:1.20.1250.20 189 371 2.6E-13 T 23-10-2018 STK_00760 318466be5b69b92f206094d0544a5996 400 Gene3D G3DSA:1.10.540.10 5 129 2.2E-37 T 23-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 STK_00760 318466be5b69b92f206094d0544a5996 400 SUPERFAMILY SSF56645 9 252 1.14E-80 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 STK_00760 318466be5b69b92f206094d0544a5996 400 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 131 229 2.9E-26 T 23-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 STK_00760 318466be5b69b92f206094d0544a5996 400 Gene3D G3DSA:1.20.140.10 247 396 1.2E-49 T 23-10-2018 STK_00760 318466be5b69b92f206094d0544a5996 400 SUPERFAMILY SSF47203 239 393 6.12E-52 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 STK_00760 318466be5b69b92f206094d0544a5996 400 PIRSF PIRSF016578 9 110 2.9E-5 T 23-10-2018 STK_00760 318466be5b69b92f206094d0544a5996 400 PIRSF PIRSF016578 129 390 3.1E-20 T 23-10-2018 STK_00760 318466be5b69b92f206094d0544a5996 400 Gene3D G3DSA:2.40.110.10 130 246 1.5E-41 T 23-10-2018 STK_00760 318466be5b69b92f206094d0544a5996 400 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 16 127 1.3E-33 T 23-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 STK_00760 318466be5b69b92f206094d0544a5996 400 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 241 389 3.9E-44 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 STK_13850 9ef724d0633ed2d4b4f1ce6a01929949 207 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 10 199 35.187 T 23-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 STK_13850 9ef724d0633ed2d4b4f1ce6a01929949 207 Gene3D G3DSA:3.30.1130.10 67 201 1.7E-43 T 23-10-2018 STK_13850 9ef724d0633ed2d4b4f1ce6a01929949 207 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 125 135 - T 23-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 STK_13850 9ef724d0633ed2d4b4f1ce6a01929949 207 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 75 91 - T 23-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 STK_13850 9ef724d0633ed2d4b4f1ce6a01929949 207 Gene3D G3DSA:1.10.286.10 1 56 5.8E-17 T 23-10-2018 STK_13850 9ef724d0633ed2d4b4f1ce6a01929949 207 SUPERFAMILY SSF55620 4 199 1.04E-61 T 23-10-2018 STK_13850 9ef724d0633ed2d4b4f1ce6a01929949 207 Pfam PF01227 GTP cyclohydrolase I 14 198 2.1E-62 T 23-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 STK_13010 7bbce3b0a64f0c9e355ed8ebe048405a 460 SUPERFAMILY SSF51569 2 281 9.82E-80 T 23-10-2018 STK_13010 7bbce3b0a64f0c9e355ed8ebe048405a 460 Gene3D G3DSA:1.10.238.260 271 379 2.1E-28 T 23-10-2018 STK_13010 7bbce3b0a64f0c9e355ed8ebe048405a 460 Gene3D G3DSA:3.20.20.70 1 270 5.8E-87 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_13010 7bbce3b0a64f0c9e355ed8ebe048405a 460 Pfam PF01037 Lrp/AsnC ligand binding domain 388 458 1.2E-15 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain STK_13010 7bbce3b0a64f0c9e355ed8ebe048405a 460 Gene3D G3DSA:3.30.70.920 380 460 2.4E-18 T 23-10-2018 STK_13010 7bbce3b0a64f0c9e355ed8ebe048405a 460 TIGRFAM TIGR02146 LysS_fung_arch: homocitrate synthase 5 352 2.0E-174 T 23-10-2018 IPR011872 Homocitrate synthase, fungi/archaea GO:0004410|GO:0019752|GO:0019878|GO:0046912 KEGG: 00300+2.3.3.14|KEGG: 00620+2.3.3.14|MetaCyc: PWY-3081|MetaCyc: PWY-7710 STK_13010 7bbce3b0a64f0c9e355ed8ebe048405a 460 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 194 207 - T 23-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 STK_13010 7bbce3b0a64f0c9e355ed8ebe048405a 460 Pfam PF00682 HMGL-like 3 264 1.1E-71 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 STK_13010 7bbce3b0a64f0c9e355ed8ebe048405a 460 SUPERFAMILY SSF54909 384 459 3.08E-15 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel STK_00090 ffcd57054465955f14b4491e1716c018 279 Pfam PF03787 RAMP superfamily 22 224 2.0E-24 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein STK_00090 ffcd57054465955f14b4491e1716c018 279 TIGRFAM TIGR02581 cas_cyan_RAMP: CRISPR-associated RAMP protein, SSO1426 family 13 230 8.7E-99 T 23-10-2018 IPR013411 CRISPR-associated RAMP TM1809 STK_06965 d45a1dd03185b661e2be6696bbce2315 74 Hamap MF_01245 UPF0248 protein . 7 74 15.633 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 STK_06965 d45a1dd03185b661e2be6696bbce2315 74 Pfam PF04457 Protein of unknown function (DUF504) 23 74 4.3E-19 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 STK_06070 a55a8dfd86ca0365536c713270341537 316 Pfam PF02769 AIR synthase related protein, C-terminal domain 140 283 1.2E-9 T 23-10-2018 IPR010918 PurM-like, C-terminal domain STK_06070 a55a8dfd86ca0365536c713270341537 316 Pfam PF00586 AIR synthase related protein, N-terminal domain 40 121 2.2E-10 T 23-10-2018 IPR016188 PurM-like, N-terminal domain STK_06070 a55a8dfd86ca0365536c713270341537 316 Gene3D G3DSA:3.90.650.10 136 304 6.2E-24 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily STK_06070 a55a8dfd86ca0365536c713270341537 316 SUPERFAMILY SSF55326 3 121 8.2E-19 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily STK_06070 a55a8dfd86ca0365536c713270341537 316 PIRSF PIRSF005644 1 306 1.9E-70 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE STK_06070 a55a8dfd86ca0365536c713270341537 316 SUPERFAMILY SSF56042 137 292 3.66E-17 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily STK_06070 a55a8dfd86ca0365536c713270341537 316 Gene3D G3DSA:3.30.1330.10 11 130 1.2E-18 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily STK_05780 abc48326715a38e79dcb92a684eb32c3 188 Hamap MF_01510 GMP synthase [glutamine-hydrolyzing] subunit A [guaAA]. 2 188 39.5 T 23-10-2018 IPR023686 GMP synthase (glutamine-hydrolyzing) subunit A GO:0003922 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 STK_05780 abc48326715a38e79dcb92a684eb32c3 188 SUPERFAMILY SSF52317 2 187 1.53E-49 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_05780 abc48326715a38e79dcb92a684eb32c3 188 Gene3D G3DSA:3.40.50.880 1 188 1.8E-52 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_05780 abc48326715a38e79dcb92a684eb32c3 188 Pfam PF00117 Glutamine amidotransferase class-I 5 183 9.9E-35 T 23-10-2018 IPR017926 Glutamine amidotransferase STK_05780 abc48326715a38e79dcb92a684eb32c3 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 162 175 4.6E-8 T 23-10-2018 STK_05780 abc48326715a38e79dcb92a684eb32c3 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 45 54 4.6E-8 T 23-10-2018 STK_05780 abc48326715a38e79dcb92a684eb32c3 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 4.6E-8 T 23-10-2018 STK_05780 abc48326715a38e79dcb92a684eb32c3 188 PRINTS PR00097 Anthranilate synthase component II signature 74 85 4.3E-6 T 23-10-2018 STK_05780 abc48326715a38e79dcb92a684eb32c3 188 PRINTS PR00097 Anthranilate synthase component II signature 162 175 4.3E-6 T 23-10-2018 STK_05780 abc48326715a38e79dcb92a684eb32c3 188 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 3 187 9.2E-59 T 23-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 STK_22960 3a611abdeedd4263985f59fd60ca9271 331 Gene3D G3DSA:3.30.465.40 3 190 4.5E-37 T 23-10-2018 STK_22960 3a611abdeedd4263985f59fd60ca9271 331 Pfam PF01565 FAD binding domain 11 139 1.6E-27 T 23-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 STK_22960 3a611abdeedd4263985f59fd60ca9271 331 SUPERFAMILY SSF56176 11 178 2.8E-38 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 STK_10070 5989e1a14a14cb0e35c04ec7a681a37f 216 SUPERFAMILY SSF48613 1 207 1.11E-66 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 STK_10070 5989e1a14a14cb0e35c04ec7a681a37f 216 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 12 208 1.7E-51 T 23-10-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 STK_10070 5989e1a14a14cb0e35c04ec7a681a37f 216 Pfam PF03070 TENA/THI-4/PQQC family 10 208 4.1E-42 T 23-10-2018 IPR004305 Thiaminase-2/PQQC STK_10070 5989e1a14a14cb0e35c04ec7a681a37f 216 Gene3D G3DSA:1.20.910.10 1 211 1.5E-62 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 STK_09580 b76a48f38126f514a32c16b9e4eb303c 107 Gene3D G3DSA:3.30.160.60 49 99 9.4E-11 T 23-10-2018 STK_09580 b76a48f38126f514a32c16b9e4eb303c 107 Pfam PF00096 Zinc finger, C2H2 type 77 99 1.3E-4 T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 STK_09580 b76a48f38126f514a32c16b9e4eb303c 107 SMART SM00355 76 99 0.12 T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 STK_09580 b76a48f38126f514a32c16b9e4eb303c 107 SMART SM00355 50 74 0.62 T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 STK_09580 b76a48f38126f514a32c16b9e4eb303c 107 SUPERFAMILY SSF57667 49 94 1.57E-5 T 23-10-2018 IPR036236 Zinc finger C2H2 superfamily STK_09580 b76a48f38126f514a32c16b9e4eb303c 107 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 78 99 - T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 STK_14150 8d2e21a6db63cb9a27a46db6e6e04db3 540 Gene3D G3DSA:3.30.56.10 270 338 6.4E-22 T 23-10-2018 STK_14150 8d2e21a6db63cb9a27a46db6e6e04db3 540 SMART SM00873 91 250 5.6E-16 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 STK_14150 8d2e21a6db63cb9a27a46db6e6e04db3 540 SUPERFAMILY SSF46955 270 342 1.46E-17 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily STK_14150 8d2e21a6db63cb9a27a46db6e6e04db3 540 Pfam PF03484 tRNA synthetase B5 domain 273 338 9.5E-18 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 STK_14150 8d2e21a6db63cb9a27a46db6e6e04db3 540 Gene3D G3DSA:3.30.56.10 1 73 2.5E-10 T 23-10-2018 STK_14150 8d2e21a6db63cb9a27a46db6e6e04db3 540 SUPERFAMILY SSF46955 15 73 3.39E-6 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily STK_14150 8d2e21a6db63cb9a27a46db6e6e04db3 540 Gene3D G3DSA:3.30.930.10 357 536 1.6E-44 T 23-10-2018 STK_14150 8d2e21a6db63cb9a27a46db6e6e04db3 540 SMART SM00874 270 338 6.2E-23 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 STK_14150 8d2e21a6db63cb9a27a46db6e6e04db3 540 SUPERFAMILY SSF55681 335 536 1.43E-44 T 23-10-2018 STK_14150 8d2e21a6db63cb9a27a46db6e6e04db3 540 Gene3D G3DSA:3.50.40.10 74 266 2.0E-55 T 23-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 STK_14150 8d2e21a6db63cb9a27a46db6e6e04db3 540 Hamap MF_00284 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 534 34.112 T 23-10-2018 IPR022918 Phenylalanine-tRNA ligase beta chain 2, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 STK_14150 8d2e21a6db63cb9a27a46db6e6e04db3 540 TIGRFAM TIGR00471 pheT_arch: phenylalanine--tRNA ligase, beta subunit 1 534 8.4E-139 T 23-10-2018 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 STK_14150 8d2e21a6db63cb9a27a46db6e6e04db3 540 Pfam PF03483 B3/4 domain 92 229 4.0E-12 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 STK_20040 95fab9d067c91d9a8d285c5cf359586d 140 Pfam PF01850 PIN domain 6 120 4.3E-15 T 23-10-2018 IPR002716 PIN domain STK_20040 95fab9d067c91d9a8d285c5cf359586d 140 Gene3D G3DSA:3.40.50.1010 5 137 7.2E-7 T 23-10-2018 STK_20040 95fab9d067c91d9a8d285c5cf359586d 140 SUPERFAMILY SSF88723 6 124 3.36E-15 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_15260 290525d26f133085aed249c6de66c229 352 Gene3D G3DSA:3.40.50.11030 215 352 7.7E-54 T 23-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily STK_15260 290525d26f133085aed249c6de66c229 352 Pfam PF01300 Telomere recombination 23 198 7.6E-56 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 STK_15260 290525d26f133085aed249c6de66c229 352 Gene3D G3DSA:3.90.870.10 1 214 1.6E-88 T 23-10-2018 STK_15260 290525d26f133085aed249c6de66c229 352 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 209 1.2E-63 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 STK_15260 290525d26f133085aed249c6de66c229 352 SUPERFAMILY SSF55821 3 212 3.36E-68 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily STK_15260 290525d26f133085aed249c6de66c229 352 PIRSF PIRSF004930 1 342 4.4E-131 T 23-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 STK_15260 290525d26f133085aed249c6de66c229 352 Pfam PF03481 Putative GTP-binding controlling metal-binding 201 336 5.5E-22 T 23-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain STK_03170 21c529f1ad056c8e1d600b9bac6e5413 603 Gene3D G3DSA:3.40.50.300 81 327 5.6E-61 T 23-10-2018 STK_03170 21c529f1ad056c8e1d600b9bac6e5413 603 PRINTS PR01868 ABC transporter family E signature 75 95 5.5E-53 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 STK_03170 21c529f1ad056c8e1d600b9bac6e5413 603 PRINTS PR01868 ABC transporter family E signature 136 152 5.5E-53 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 STK_03170 21c529f1ad056c8e1d600b9bac6e5413 603 PRINTS PR01868 ABC transporter family E signature 103 128 5.5E-53 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 STK_03170 21c529f1ad056c8e1d600b9bac6e5413 603 PRINTS PR01868 ABC transporter family E signature 19 34 5.5E-53 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 STK_03170 21c529f1ad056c8e1d600b9bac6e5413 603 PRINTS PR01868 ABC transporter family E signature 48 72 5.5E-53 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 STK_03170 21c529f1ad056c8e1d600b9bac6e5413 603 PRINTS PR01868 ABC transporter family E signature 152 178 5.5E-53 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 STK_03170 21c529f1ad056c8e1d600b9bac6e5413 603 SUPERFAMILY SSF52540 95 285 9.94E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_03170 21c529f1ad056c8e1d600b9bac6e5413 603 Gene3D G3DSA:3.40.50.300 328 595 7.5E-61 T 23-10-2018 STK_03170 21c529f1ad056c8e1d600b9bac6e5413 603 Pfam PF00005 ABC transporter 366 487 2.8E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_03170 21c529f1ad056c8e1d600b9bac6e5413 603 SMART SM00382 98 288 9.1E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_03170 21c529f1ad056c8e1d600b9bac6e5413 603 SMART SM00382 367 574 1.2E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_03170 21c529f1ad056c8e1d600b9bac6e5413 603 SUPERFAMILY SSF54862 4 121 3.81E-19 T 23-10-2018 STK_03170 21c529f1ad056c8e1d600b9bac6e5413 603 Gene3D G3DSA:3.30.70.20 9 80 1.3E-9 T 23-10-2018 STK_03170 21c529f1ad056c8e1d600b9bac6e5413 603 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 1 32 3.4E-12 T 23-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain STK_03170 21c529f1ad056c8e1d600b9bac6e5413 603 SUPERFAMILY SSF52540 365 535 3.86E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_03170 21c529f1ad056c8e1d600b9bac6e5413 603 Pfam PF00005 ABC transporter 97 240 9.3E-18 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_03170 21c529f1ad056c8e1d600b9bac6e5413 603 Pfam PF00037 4Fe-4S binding domain 44 67 7.9E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_03170 21c529f1ad056c8e1d600b9bac6e5413 603 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_03170 21c529f1ad056c8e1d600b9bac6e5413 603 ProSitePatterns PS00211 ABC transporters family signature. 213 227 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 STK_19860 36f92c70d2821b1e7e15ac3ff5109c4a 229 SUPERFAMILY SSF48452 7 140 2.81E-11 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 STK_19860 36f92c70d2821b1e7e15ac3ff5109c4a 229 Gene3D G3DSA:1.25.40.10 3 189 2.6E-14 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 STK_07830 4974bfb0ff747639d41daa6771d7b334 659 Pfam PF00501 AMP-binding enzyme 90 530 1.0E-81 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 STK_07830 4974bfb0ff747639d41daa6771d7b334 659 Gene3D G3DSA:3.40.50.12780 57 524 5.1E-95 T 23-10-2018 STK_07830 4974bfb0ff747639d41daa6771d7b334 659 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 24 648 3.4E-228 T 23-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 STK_07830 4974bfb0ff747639d41daa6771d7b334 659 Pfam PF13193 AMP-binding enzyme C-terminal domain 539 616 3.7E-24 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain STK_07830 4974bfb0ff747639d41daa6771d7b334 659 Gene3D G3DSA:3.30.300.30 527 656 3.5E-26 T 23-10-2018 STK_07830 4974bfb0ff747639d41daa6771d7b334 659 ProSitePatterns PS00455 Putative AMP-binding domain signature. 262 273 - T 23-10-2018 IPR020845 AMP-binding, conserved site STK_07830 4974bfb0ff747639d41daa6771d7b334 659 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 28 83 2.6E-19 T 23-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 STK_07830 4974bfb0ff747639d41daa6771d7b334 659 SUPERFAMILY SSF56801 20 646 1.02E-152 T 23-10-2018 STK_26220 464ebd8fa998ba5b5a96ee894382d220 702 Gene3D G3DSA:2.130.10.10 251 397 4.6E-10 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 STK_26220 464ebd8fa998ba5b5a96ee894382d220 702 Gene3D G3DSA:2.130.10.10 398 511 5.5E-17 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 STK_26220 464ebd8fa998ba5b5a96ee894382d220 702 SUPERFAMILY SSF63825 540 631 4.18E-5 T 23-10-2018 STK_26220 464ebd8fa998ba5b5a96ee894382d220 702 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 86 125 2.7E-9 T 23-10-2018 IPR011964 YVTN beta-propeller repeat STK_26220 464ebd8fa998ba5b5a96ee894382d220 702 Pfam PF13360 PQQ-like domain 394 644 1.2E-6 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat STK_26220 464ebd8fa998ba5b5a96ee894382d220 702 Gene3D G3DSA:2.130.10.10 24 240 6.0E-21 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 STK_26220 464ebd8fa998ba5b5a96ee894382d220 702 SUPERFAMILY SSF63825 216 412 4.45E-13 T 23-10-2018 STK_26220 464ebd8fa998ba5b5a96ee894382d220 702 SUPERFAMILY SSF50969 45 489 7.85E-27 T 23-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like STK_05980 e7e0793fac3486e707adef010e8ddb71 278 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 14 254 6.6E-42 T 23-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 STK_05980 e7e0793fac3486e707adef010e8ddb71 278 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 9 266 13.876 T 23-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 STK_05980 e7e0793fac3486e707adef010e8ddb71 278 Pfam PF00902 Sec-independent protein translocase protein (TatC) 16 237 1.1E-49 T 23-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 STK_05980 e7e0793fac3486e707adef010e8ddb71 278 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 180 208 2.3E-36 T 23-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 STK_05980 e7e0793fac3486e707adef010e8ddb71 278 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 110 128 2.3E-36 T 23-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 STK_05980 e7e0793fac3486e707adef010e8ddb71 278 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 128 154 2.3E-36 T 23-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 STK_05980 e7e0793fac3486e707adef010e8ddb71 278 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 13 40 2.3E-36 T 23-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 STK_21480 6c1466390f8afaa69ffbea4d9a63efaf 275 Pfam PF01261 Xylose isomerase-like TIM barrel 25 229 3.2E-25 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain STK_21480 6c1466390f8afaa69ffbea4d9a63efaf 275 SMART SM00518 8 268 9.9E-72 T 23-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 STK_21480 6c1466390f8afaa69ffbea4d9a63efaf 275 SUPERFAMILY SSF51658 4 270 2.21E-53 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily STK_21480 6c1466390f8afaa69ffbea4d9a63efaf 275 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 67 75 - T 23-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 STK_21480 6c1466390f8afaa69ffbea4d9a63efaf 275 Gene3D G3DSA:3.20.20.150 9 272 1.3E-38 T 23-10-2018 STK_21990 0a19c86b2ff89e7e29b2327999f5e66b 656 Gene3D G3DSA:2.160.20.60 362 620 7.1E-26 T 23-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 STK_21990 0a19c86b2ff89e7e29b2327999f5e66b 656 SUPERFAMILY SSF56235 7 353 1.33E-58 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_21990 0a19c86b2ff89e7e29b2327999f5e66b 656 PIRSF PIRSF036632 1 656 0.0 T 23-10-2018 IPR012075 Glutamate synthase, large subunit domains 1/3 fusion STK_21990 0a19c86b2ff89e7e29b2327999f5e66b 656 Pfam PF01493 GXGXG motif 388 541 4.7E-23 T 23-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 STK_21990 0a19c86b2ff89e7e29b2327999f5e66b 656 Gene3D G3DSA:3.60.20.10 115 347 9.9E-32 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_21990 0a19c86b2ff89e7e29b2327999f5e66b 656 SUPERFAMILY SSF69336 360 571 2.09E-43 T 23-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 STK_23540 d9286184f9be4fd463ebe599b22f228e 299 SUPERFAMILY SSF53067 107 292 9.36E-47 T 23-10-2018 STK_23540 d9286184f9be4fd463ebe599b22f228e 299 SUPERFAMILY SSF53067 1 104 7.94E-21 T 23-10-2018 STK_23540 d9286184f9be4fd463ebe599b22f228e 299 Gene3D G3DSA:3.30.420.40 106 273 1.8E-107 T 23-10-2018 STK_23540 d9286184f9be4fd463ebe599b22f228e 299 Gene3D G3DSA:3.30.420.40 4 285 1.8E-107 T 23-10-2018 STK_23540 d9286184f9be4fd463ebe599b22f228e 299 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 285 1.0E-40 T 23-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 STK_07500 76d9ad9f582dfaf93aa2e43db24c2d1d 125 Pfam PF05168 HEPN domain 6 122 2.0E-26 T 23-10-2018 IPR007842 HEPN domain STK_07500 76d9ad9f582dfaf93aa2e43db24c2d1d 125 SMART SM00748 10 116 6.0E-28 T 23-10-2018 IPR007842 HEPN domain STK_07500 76d9ad9f582dfaf93aa2e43db24c2d1d 125 SUPERFAMILY SSF81593 9 119 8.63E-21 T 23-10-2018 STK_07500 76d9ad9f582dfaf93aa2e43db24c2d1d 125 Gene3D G3DSA:1.20.120.330 2 125 5.5E-20 T 23-10-2018 STK_17525 15c8e8c3dcf5ce3084e7a24d3be46c80 110 SUPERFAMILY SSF81301 5 94 1.46E-12 T 23-10-2018 STK_17525 15c8e8c3dcf5ce3084e7a24d3be46c80 110 Gene3D G3DSA:3.30.460.10 2 107 1.4E-9 T 23-10-2018 STK_17525 15c8e8c3dcf5ce3084e7a24d3be46c80 110 Pfam PF01909 Nucleotidyltransferase domain 8 80 5.5E-8 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_17100 c6d7bcd3353fe06075e077e0f2188f01 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 1.0E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 STK_17100 c6d7bcd3353fe06075e077e0f2188f01 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 1.0E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 STK_17100 c6d7bcd3353fe06075e077e0f2188f01 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 1.0E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 STK_17100 c6d7bcd3353fe06075e077e0f2188f01 146 Pfam PF13463 Winged helix DNA-binding domain 35 100 4.6E-13 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 STK_17100 c6d7bcd3353fe06075e077e0f2188f01 146 SUPERFAMILY SSF46785 9 142 2.1E-30 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_17100 c6d7bcd3353fe06075e077e0f2188f01 146 Gene3D G3DSA:1.10.10.10 1 146 6.7E-42 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_17100 c6d7bcd3353fe06075e077e0f2188f01 146 SMART SM00347 28 127 2.0E-16 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 STK_21210 b0eb38f879a1dbfc2e0fa984929e1262 237 Gene3D G3DSA:3.40.50.10700 155 236 4.0E-13 T 23-10-2018 STK_21210 b0eb38f879a1dbfc2e0fa984929e1262 237 PIRSF PIRSF016210 1 237 3.0E-72 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 STK_21210 b0eb38f879a1dbfc2e0fa984929e1262 237 Gene3D G3DSA:3.40.630.50 3 154 7.2E-36 T 23-10-2018 STK_21210 b0eb38f879a1dbfc2e0fa984929e1262 237 Pfam PF04414 D-aminoacyl-tRNA deacylase 37 233 5.0E-57 T 23-10-2018 IPR007508 D-aminoacyl-tRNA deacylase DtdA GO:0016788|GO:0051499 STK_21210 b0eb38f879a1dbfc2e0fa984929e1262 237 Hamap MF_00562 D-aminoacyl-tRNA deacylase [dtdA]. 2 236 31.357 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 STK_21210 b0eb38f879a1dbfc2e0fa984929e1262 237 SUPERFAMILY SSF142535 3 234 1.02E-67 T 23-10-2018 STK_25420 04bec14268936d1d847be07e9b43cc2d 323 SMART SM00382 32 244 5.3E-18 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_25420 04bec14268936d1d847be07e9b43cc2d 323 Gene3D G3DSA:3.40.50.300 1 323 1.1E-100 T 23-10-2018 STK_25420 04bec14268936d1d847be07e9b43cc2d 323 Pfam PF00005 ABC transporter 23 187 2.1E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_25420 04bec14268936d1d847be07e9b43cc2d 323 SUPERFAMILY SSF52540 3 265 8.47E-68 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_25420 04bec14268936d1d847be07e9b43cc2d 323 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 321 7.0E-28 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 STK_25420 04bec14268936d1d847be07e9b43cc2d 323 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 302 2.4E-19 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 STK_04015 0d3e2c40348580553e8a5a4bcab34987 96 Hamap MF_00721 50S ribosomal protein L14e [rpl14e]. 1 80 30.299 T 23-10-2018 IPR023651 Ribosomal protein L14e GO:0003735|GO:0005840|GO:0006412 STK_04015 0d3e2c40348580553e8a5a4bcab34987 96 Gene3D G3DSA:2.30.30.30 2 87 2.6E-38 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 STK_04015 0d3e2c40348580553e8a5a4bcab34987 96 SUPERFAMILY SSF50104 2 89 5.11E-27 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily STK_03260 8599558455994c9d0aab30891d6123ce 143 SUPERFAMILY SSF50182 9 136 3.27E-17 T 23-10-2018 IPR010920 LSM domain superfamily STK_03260 8599558455994c9d0aab30891d6123ce 143 Gene3D G3DSA:3.30.310.60 76 136 1.2E-21 T 23-10-2018 IPR037156 Like-Sm ribonucleoprotein, C-terminal domain superfamily STK_03260 8599558455994c9d0aab30891d6123ce 143 Pfam PF14894 Lsm C-terminal 78 140 1.8E-30 T 23-10-2018 IPR028277 Lsm, C-terminal STK_03260 8599558455994c9d0aab30891d6123ce 143 Gene3D G3DSA:2.30.30.100 6 72 1.1E-10 T 23-10-2018 STK_09870 3de584ee86f9f10fead52aa008706459 428 Pfam PF13635 Domain of unknown function (DUF4143) 264 368 3.2E-13 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 STK_09870 3de584ee86f9f10fead52aa008706459 428 Pfam PF13173 AAA domain 42 175 1.1E-31 T 23-10-2018 STK_09870 3de584ee86f9f10fead52aa008706459 428 SUPERFAMILY SSF52540 23 229 2.98E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_09870 3de584ee86f9f10fead52aa008706459 428 Gene3D G3DSA:3.40.50.300 77 164 2.2E-5 T 23-10-2018 STK_09870 3de584ee86f9f10fead52aa008706459 428 SMART SM00382 39 168 0.0039 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_07750 9c64c1f783cf39c6dbfdc92a2a3c4357 174 Gene3D G3DSA:3.40.50.150 13 174 3.5E-40 T 23-10-2018 STK_07750 9c64c1f783cf39c6dbfdc92a2a3c4357 174 Pfam PF08241 Methyltransferase domain 33 123 3.6E-19 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 STK_07750 9c64c1f783cf39c6dbfdc92a2a3c4357 174 SUPERFAMILY SSF53335 19 157 2.76E-26 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_11960 bbccf5c8def1d0937202fe6ef3fa1fbd 472 Gene3D G3DSA:3.50.50.60 4 361 2.2E-147 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_11960 bbccf5c8def1d0937202fe6ef3fa1fbd 472 SUPERFAMILY SSF56425 206 314 4.34E-29 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 STK_11960 bbccf5c8def1d0937202fe6ef3fa1fbd 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 165 183 3.9E-8 T 23-10-2018 STK_11960 bbccf5c8def1d0937202fe6ef3fa1fbd 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 2 21 3.9E-8 T 23-10-2018 STK_11960 bbccf5c8def1d0937202fe6ef3fa1fbd 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 317 339 3.9E-8 T 23-10-2018 STK_11960 bbccf5c8def1d0937202fe6ef3fa1fbd 472 Gene3D G3DSA:1.20.58.100 376 472 6.2E-40 T 23-10-2018 STK_11960 bbccf5c8def1d0937202fe6ef3fa1fbd 472 Pfam PF00890 FAD binding domain 4 354 1.0E-69 T 23-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 STK_11960 bbccf5c8def1d0937202fe6ef3fa1fbd 472 Gene3D G3DSA:3.90.700.10 214 309 2.2E-147 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 STK_11960 bbccf5c8def1d0937202fe6ef3fa1fbd 472 Pfam PF02910 Fumarate reductase flavoprotein C-term 428 466 1.6E-6 T 23-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 STK_11960 bbccf5c8def1d0937202fe6ef3fa1fbd 472 SUPERFAMILY SSF51905 4 382 2.21E-52 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_11960 bbccf5c8def1d0937202fe6ef3fa1fbd 472 SUPERFAMILY SSF46977 395 468 6.41E-19 T 23-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 STK_12670 eb803d895567fbf2660c6468095e49a0 138 Pfam PF01886 Protein of unknown function DUF61 3 119 3.9E-18 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 STK_12670 eb803d895567fbf2660c6468095e49a0 138 PIRSF PIRSF024484 1 138 1.1E-71 T 23-10-2018 IPR012357 Uncharacterised conserved protein UCP024484 STK_02547 e00df224bc88dc8a2a890e47ae752c1a 32 Pfam PF05584 Sulfolobus plasmid regulatory protein 1 30 2.0E-14 T 23-10-2018 IPR008848 Plasmid regulator, Sulfolobaceae STK_02547 e00df224bc88dc8a2a890e47ae752c1a 32 Gene3D G3DSA:1.10.10.10 1 32 1.4E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_20330 6118c1ab34674a7ebb7213b5253a2287 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 71 253 2.2E-14 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 STK_20330 6118c1ab34674a7ebb7213b5253a2287 263 SUPERFAMILY SSF161098 5 250 2.09E-34 T 23-10-2018 IPR035906 MetI-like superfamily STK_20330 6118c1ab34674a7ebb7213b5253a2287 263 Gene3D G3DSA:1.10.3720.10 3 257 2.0E-37 T 23-10-2018 IPR035906 MetI-like superfamily STK_11940 571b946373daa9d076b830d9484882dc 275 Pfam PF04055 Radical SAM superfamily 33 188 1.6E-7 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_11940 571b946373daa9d076b830d9484882dc 275 Gene3D G3DSA:3.20.20.70 13 239 3.1E-20 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_11940 571b946373daa9d076b830d9484882dc 275 SMART SM00729 25 231 2.6E-25 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 STK_11940 571b946373daa9d076b830d9484882dc 275 SUPERFAMILY SSF102114 32 259 2.49E-32 T 23-10-2018 STK_23690 29d86215f5d308a9020d3b4131c1fbee 396 SUPERFAMILY SSF54862 22 105 1.6E-6 T 23-10-2018 STK_23690 29d86215f5d308a9020d3b4131c1fbee 396 Gene3D G3DSA:3.30.70.20 14 88 1.2E-5 T 23-10-2018 STK_23690 29d86215f5d308a9020d3b4131c1fbee 396 Pfam PF02754 Cysteine-rich domain 295 374 3.4E-5 T 23-10-2018 IPR004017 Cysteine-rich domain STK_23690 29d86215f5d308a9020d3b4131c1fbee 396 Pfam PF02754 Cysteine-rich domain 170 253 4.3E-11 T 23-10-2018 IPR004017 Cysteine-rich domain STK_23690 29d86215f5d308a9020d3b4131c1fbee 396 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 68 79 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_19810 58af582a03236d1edebf6fb3f15fe687 237 Pfam PF13610 DDE domain 81 191 2.9E-6 T 23-10-2018 IPR032874 DDE domain STK_14030 f632a3c782cfb5b947f8f55731d6f5b1 460 SUPERFAMILY SSF53448 42 310 1.78E-35 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_14030 f632a3c782cfb5b947f8f55731d6f5b1 460 Pfam PF13632 Glycosyl transferase family group 2 133 348 2.1E-21 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 STK_14030 f632a3c782cfb5b947f8f55731d6f5b1 460 Gene3D G3DSA:3.90.550.10 35 251 1.9E-32 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_09417 b6656eb09bf6b19f3b6a33c3f4321b1f 95 Pfam PF00935 Ribosomal protein L44 16 91 2.2E-28 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_09417 b6656eb09bf6b19f3b6a33c3f4321b1f 95 SUPERFAMILY SSF57829 1 92 1.57E-30 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 STK_09417 b6656eb09bf6b19f3b6a33c3f4321b1f 95 Hamap MF_01476 50S ribosomal protein L44e [rpl44e]. 1 91 24.273 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_09417 b6656eb09bf6b19f3b6a33c3f4321b1f 95 Gene3D G3DSA:3.10.450.80 1 95 8.2E-30 T 23-10-2018 STK_09417 b6656eb09bf6b19f3b6a33c3f4321b1f 95 ProDom PD002841 RIBOSOMAL RIBONUCLEOPROTEIN 60S L44 L44E L41 RESISTANCE 50S ANTIBIOTIC CYCLOHEXIMIDE 9 92 1.0E-42 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_08190 a3e77b4f4f01aadb5700c055d3ad8476 200 SUPERFAMILY SSF56524 5 185 1.29E-64 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 STK_08190 a3e77b4f4f01aadb5700c055d3ad8476 200 Gene3D G3DSA:3.90.420.10 8 196 3.6E-53 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 STK_08190 a3e77b4f4f01aadb5700c055d3ad8476 200 Pfam PF00174 Oxidoreductase molybdopterin binding domain 22 167 2.2E-40 T 23-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 STK_22840 4f4d1bfa2ee149c2527ac49638807d7e 357 SUPERFAMILY SSF53448 1 306 9.62E-66 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_22840 4f4d1bfa2ee149c2527ac49638807d7e 357 Gene3D G3DSA:3.90.550.10 2 229 9.7E-62 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_22840 4f4d1bfa2ee149c2527ac49638807d7e 357 Pfam PF00483 Nucleotidyl transferase 4 225 5.1E-35 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 STK_22840 4f4d1bfa2ee149c2527ac49638807d7e 357 Gene3D G3DSA:2.160.10.10 230 356 4.4E-14 T 23-10-2018 STK_22040 13c6cd5745faf8b8b725ce09164aa1ce 297 Gene3D G3DSA:1.20.120.1780 178 297 1.9E-23 T 23-10-2018 STK_22040 13c6cd5745faf8b8b725ce09164aa1ce 297 Gene3D G3DSA:1.10.357.140 21 177 2.4E-42 T 23-10-2018 STK_22040 13c6cd5745faf8b8b725ce09164aa1ce 297 Pfam PF01040 UbiA prenyltransferase family 31 269 8.5E-41 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 STK_22040 13c6cd5745faf8b8b725ce09164aa1ce 297 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 14 296 3.6E-92 T 23-10-2018 IPR006371 4-hydroxybenzoate polyprenyltransferase-related STK_10230 f05cbe9361c7500d1129e01f2ca14120 148 PIRSF PIRSF001263 1 148 1.2E-60 T 23-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 STK_10230 f05cbe9361c7500d1129e01f2ca14120 148 PRINTS PR01693 Cyanase signature 102 118 5.7E-29 T 23-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 STK_10230 f05cbe9361c7500d1129e01f2ca14120 148 PRINTS PR01693 Cyanase signature 133 143 5.7E-29 T 23-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 STK_10230 f05cbe9361c7500d1129e01f2ca14120 148 PRINTS PR01693 Cyanase signature 84 98 5.7E-29 T 23-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 STK_10230 f05cbe9361c7500d1129e01f2ca14120 148 PRINTS PR01693 Cyanase signature 35 52 5.7E-29 T 23-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 STK_10230 f05cbe9361c7500d1129e01f2ca14120 148 PRINTS PR01693 Cyanase signature 15 30 5.7E-29 T 23-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 STK_10230 f05cbe9361c7500d1129e01f2ca14120 148 Pfam PF02560 Cyanate lyase C-terminal domain 80 146 5.1E-28 T 23-10-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00910+4.2.1.104 STK_10230 f05cbe9361c7500d1129e01f2ca14120 148 TIGRFAM TIGR00673 cynS: cyanase 7 148 1.0E-48 T 23-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 STK_10230 f05cbe9361c7500d1129e01f2ca14120 148 SMART SM01116 76 148 4.0E-44 T 23-10-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00910+4.2.1.104 STK_10230 f05cbe9361c7500d1129e01f2ca14120 148 SUPERFAMILY SSF47413 3 75 1.18E-10 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 STK_10230 f05cbe9361c7500d1129e01f2ca14120 148 Gene3D G3DSA:1.10.260.40 2 78 1.9E-17 T 23-10-2018 STK_10230 f05cbe9361c7500d1129e01f2ca14120 148 Hamap MF_00535 Cyanate hydratase [cynS]. 1 148 53.821 T 23-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 STK_10230 f05cbe9361c7500d1129e01f2ca14120 148 SUPERFAMILY SSF55234 80 148 5.36E-28 T 23-10-2018 IPR036581 Cyanate lyase, C-terminal domain superfamily GO:0009439 KEGG: 00910+4.2.1.104 STK_10230 f05cbe9361c7500d1129e01f2ca14120 148 Gene3D G3DSA:3.30.1160.10 82 148 3.3E-25 T 23-10-2018 IPR036581 Cyanate lyase, C-terminal domain superfamily GO:0009439 KEGG: 00910+4.2.1.104 STK_20190 28fa598809a19061276daa9d28536910 661 Gene3D G3DSA:3.40.50.12780 57 526 1.7E-100 T 23-10-2018 STK_20190 28fa598809a19061276daa9d28536910 661 Pfam PF00501 AMP-binding enzyme 85 532 2.3E-88 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 STK_20190 28fa598809a19061276daa9d28536910 661 Gene3D G3DSA:3.30.300.30 528 659 1.3E-29 T 23-10-2018 STK_20190 28fa598809a19061276daa9d28536910 661 ProSitePatterns PS00455 Putative AMP-binding domain signature. 269 280 - T 23-10-2018 IPR020845 AMP-binding, conserved site STK_20190 28fa598809a19061276daa9d28536910 661 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 28 81 5.1E-19 T 23-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 STK_20190 28fa598809a19061276daa9d28536910 661 SUPERFAMILY SSF56801 22 649 1.05E-170 T 23-10-2018 STK_20190 28fa598809a19061276daa9d28536910 661 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 26 651 2.0E-280 T 23-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 STK_20190 28fa598809a19061276daa9d28536910 661 Pfam PF13193 AMP-binding enzyme C-terminal domain 541 619 2.7E-28 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain STK_23030 51d7639470ee7f09aac0a673d49aab75 238 SUPERFAMILY SSF56317 7 222 1.83E-36 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily STK_23030 51d7639470ee7f09aac0a673d49aab75 238 Pfam PF00795 Carbon-nitrogen hydrolase 14 175 1.3E-14 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 STK_23030 51d7639470ee7f09aac0a673d49aab75 238 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 114 134 - T 23-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site STK_23030 51d7639470ee7f09aac0a673d49aab75 238 Gene3D G3DSA:3.60.110.10 2 232 1.2E-37 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily STK_19573 8f1611d71f99c5be967e9d7c99d67da4 86 Gene3D G3DSA:3.30.420.40 1 83 1.4E-18 T 23-10-2018 STK_19573 8f1611d71f99c5be967e9d7c99d67da4 86 Pfam PF02543 Carbamoyltransferase N-terminus 11 71 3.9E-10 T 23-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 STK_20830 1a5aabeaed02ccd6618ddd895c1dea82 497 Gene3D G3DSA:2.40.50.140 4 144 9.9E-34 T 23-10-2018 STK_20830 1a5aabeaed02ccd6618ddd895c1dea82 497 SUPERFAMILY SSF50249 8 143 2.45E-29 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_20830 1a5aabeaed02ccd6618ddd895c1dea82 497 Gene3D G3DSA:3.30.930.10 162 490 7.6E-118 T 23-10-2018 STK_20830 1a5aabeaed02ccd6618ddd895c1dea82 497 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 9 492 38.153 T 23-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 STK_20830 1a5aabeaed02ccd6618ddd895c1dea82 497 Pfam PF01336 OB-fold nucleic acid binding domain 58 134 4.6E-11 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 STK_20830 1a5aabeaed02ccd6618ddd895c1dea82 497 SUPERFAMILY SSF55681 148 489 7.57E-107 T 23-10-2018 STK_20830 1a5aabeaed02ccd6618ddd895c1dea82 497 PRINTS PR00982 Lysyl-tRNA synthetase signature 248 265 1.8E-32 T 23-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 STK_20830 1a5aabeaed02ccd6618ddd895c1dea82 497 PRINTS PR00982 Lysyl-tRNA synthetase signature 230 243 1.8E-32 T 23-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 STK_20830 1a5aabeaed02ccd6618ddd895c1dea82 497 PRINTS PR00982 Lysyl-tRNA synthetase signature 185 195 1.8E-32 T 23-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 STK_20830 1a5aabeaed02ccd6618ddd895c1dea82 497 PRINTS PR00982 Lysyl-tRNA synthetase signature 374 390 1.8E-32 T 23-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 STK_20830 1a5aabeaed02ccd6618ddd895c1dea82 497 PRINTS PR00982 Lysyl-tRNA synthetase signature 201 217 1.8E-32 T 23-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 STK_20830 1a5aabeaed02ccd6618ddd895c1dea82 497 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 8 490 9.7E-161 T 23-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 STK_20830 1a5aabeaed02ccd6618ddd895c1dea82 497 Pfam PF00152 tRNA synthetases class II (D, K and N) 149 489 4.7E-82 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_22190 1718f9841d003a3890b9336051ab8429 352 Pfam PF00146 NADH dehydrogenase 26 342 2.7E-81 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_22190 1718f9841d003a3890b9336051ab8429 352 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 10 350 18.093 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_02690 fc2b28cec1207776689b5b4c64530cfc 435 SUPERFAMILY SSF50465 324 428 2.3E-39 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal STK_02690 fc2b28cec1207776689b5b4c64530cfc 435 Hamap MF_00118_A Elongation factor Tu [tuf]. 1 430 60.692 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 STK_02690 fc2b28cec1207776689b5b4c64530cfc 435 Gene3D G3DSA:3.40.50.300 1 225 1.4E-85 T 23-10-2018 STK_02690 fc2b28cec1207776689b5b4c64530cfc 435 Pfam PF03143 Elongation factor Tu C-terminal domain 321 427 2.2E-36 T 23-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal STK_02690 fc2b28cec1207776689b5b4c64530cfc 435 Gene3D G3DSA:2.40.30.10 228 321 8.3E-37 T 23-10-2018 STK_02690 fc2b28cec1207776689b5b4c64530cfc 435 Pfam PF03144 Elongation factor Tu domain 2 247 312 1.4E-15 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 STK_02690 fc2b28cec1207776689b5b4c64530cfc 435 SUPERFAMILY SSF50447 230 320 4.57E-28 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily STK_02690 fc2b28cec1207776689b5b4c64530cfc 435 Pfam PF00009 Elongation factor Tu GTP binding domain 4 202 1.3E-53 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_02690 fc2b28cec1207776689b5b4c64530cfc 435 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 199 7.1E-13 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 STK_02690 fc2b28cec1207776689b5b4c64530cfc 435 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site STK_02690 fc2b28cec1207776689b5b4c64530cfc 435 SUPERFAMILY SSF52540 1 247 3.04E-73 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_02690 fc2b28cec1207776689b5b4c64530cfc 435 TIGRFAM TIGR00483 EF-1_alpha: translation elongation factor EF-1, subunit alpha 3 431 2.3E-196 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 STK_02690 fc2b28cec1207776689b5b4c64530cfc 435 PRINTS PR00315 GTP-binding elongation factor signature 103 114 2.3E-23 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_02690 fc2b28cec1207776689b5b4c64530cfc 435 PRINTS PR00315 GTP-binding elongation factor signature 67 75 2.3E-23 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_02690 fc2b28cec1207776689b5b4c64530cfc 435 PRINTS PR00315 GTP-binding elongation factor signature 87 97 2.3E-23 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_02690 fc2b28cec1207776689b5b4c64530cfc 435 PRINTS PR00315 GTP-binding elongation factor signature 147 156 2.3E-23 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_02690 fc2b28cec1207776689b5b4c64530cfc 435 PRINTS PR00315 GTP-binding elongation factor signature 8 21 2.3E-23 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 STK_02690 fc2b28cec1207776689b5b4c64530cfc 435 Gene3D G3DSA:2.40.30.10 322 428 3.4E-43 T 23-10-2018 STK_18010 f3b81dae2cf621bdb0e96ee88fd1782d 130 Pfam PF01850 PIN domain 16 116 2.1E-6 T 23-10-2018 IPR002716 PIN domain STK_18010 f3b81dae2cf621bdb0e96ee88fd1782d 130 Gene3D G3DSA:3.40.50.1010 1 130 3.5E-30 T 23-10-2018 STK_18010 f3b81dae2cf621bdb0e96ee88fd1782d 130 SUPERFAMILY SSF88723 5 121 3.64E-15 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_18940 50567c652d3c306fcffc5e2ead2fdcd3 136 SUPERFAMILY SSF51230 13 111 9.07E-27 T 23-10-2018 IPR011053 Single hybrid motif STK_18940 50567c652d3c306fcffc5e2ead2fdcd3 136 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 9 132 34.236 T 23-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 STK_18940 50567c652d3c306fcffc5e2ead2fdcd3 136 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 53 82 - T 23-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 STK_18940 50567c652d3c306fcffc5e2ead2fdcd3 136 Gene3D G3DSA:2.40.50.100 8 133 5.4E-31 T 23-10-2018 STK_18940 50567c652d3c306fcffc5e2ead2fdcd3 136 Pfam PF01597 Glycine cleavage H-protein 14 119 6.6E-30 T 23-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate STK_01800 5cf2cbde006ae71b6559675a1658f94b 232 SMART SM00933 23 199 5.5E-23 T 23-10-2018 IPR018977 NurA domain STK_01800 5cf2cbde006ae71b6559675a1658f94b 232 Pfam PF09376 NurA domain 24 105 1.1E-4 T 23-10-2018 IPR018977 NurA domain STK_01800 5cf2cbde006ae71b6559675a1658f94b 232 Pfam PF09376 NurA domain 127 199 5.0E-6 T 23-10-2018 IPR018977 NurA domain STK_01877 41fbaffd538609e8355a9304614f9730 91 SUPERFAMILY SSF69695 10 90 6.8E-10 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 STK_01877 41fbaffd538609e8355a9304614f9730 91 Gene3D G3DSA:3.30.56.30 1 91 2.0E-29 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 STK_12335 a6f25e5dde5c3625bd8a1649e2140fa4 90 ProSitePatterns PS00150 Acylphosphatase signature 1. 9 19 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 STK_12335 a6f25e5dde5c3625bd8a1649e2140fa4 90 Pfam PF00708 Acylphosphatase 6 88 3.0E-28 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 STK_12335 a6f25e5dde5c3625bd8a1649e2140fa4 90 SUPERFAMILY SSF54975 2 88 1.35E-28 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 STK_12335 a6f25e5dde5c3625bd8a1649e2140fa4 90 ProSitePatterns PS00151 Acylphosphatase signature 2. 33 49 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 STK_12335 a6f25e5dde5c3625bd8a1649e2140fa4 90 Gene3D G3DSA:3.30.70.100 1 90 5.9E-36 T 23-10-2018 STK_14470 fa2d3da2865369eb256940f090ad6afc 572 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 197 333 3.3E-39 T 23-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 STK_14470 fa2d3da2865369eb256940f090ad6afc 572 SUPERFAMILY SSF52518 371 565 3.8E-63 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold STK_14470 fa2d3da2865369eb256940f090ad6afc 572 SUPERFAMILY SSF52467 157 364 8.11E-47 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily STK_14470 fa2d3da2865369eb256940f090ad6afc 572 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 173 5.1E-56 T 23-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 STK_14470 fa2d3da2865369eb256940f090ad6afc 572 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 431 450 - T 23-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 STK_14470 fa2d3da2865369eb256940f090ad6afc 572 Gene3D G3DSA:3.40.50.1220 192 367 2.5E-48 T 23-10-2018 STK_14470 fa2d3da2865369eb256940f090ad6afc 572 SUPERFAMILY SSF52518 2 180 1.23E-59 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold STK_14470 fa2d3da2865369eb256940f090ad6afc 572 Gene3D G3DSA:3.40.50.970 368 568 6.9E-61 T 23-10-2018 STK_14470 fa2d3da2865369eb256940f090ad6afc 572 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 3 564 3.2E-188 T 23-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 STK_14470 fa2d3da2865369eb256940f090ad6afc 572 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 394 541 4.2E-46 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 STK_14470 fa2d3da2865369eb256940f090ad6afc 572 Gene3D G3DSA:3.40.50.970 1 183 1.2E-69 T 23-10-2018 STK_13760 d5dd9bbb50a65bbfc57a5f4c72a9040a 389 PIRSF PIRSF000484 41 389 1.3E-57 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 STK_13760 d5dd9bbb50a65bbfc57a5f4c72a9040a 389 Gene3D G3DSA:3.90.1170.20 1 106 1.6E-37 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 STK_13760 d5dd9bbb50a65bbfc57a5f4c72a9040a 389 SUPERFAMILY SSF54675 2 115 8.68E-33 T 23-10-2018 STK_13760 d5dd9bbb50a65bbfc57a5f4c72a9040a 389 Gene3D G3DSA:3.20.140.10 346 389 1.1E-5 T 23-10-2018 STK_13760 d5dd9bbb50a65bbfc57a5f4c72a9040a 389 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 115 301 1.6E-22 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 STK_13760 d5dd9bbb50a65bbfc57a5f4c72a9040a 389 SUPERFAMILY SSF51690 112 386 6.04E-79 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 STK_13760 d5dd9bbb50a65bbfc57a5f4c72a9040a 389 Gene3D G3DSA:3.20.20.70 107 295 9.6E-63 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_04830 f521e452ce9b33e1bef8072afc736982 349 Hamap MF_00424 Peptide chain release factor subunit 1 [prf1]. 1 349 41.193 T 23-10-2018 IPR020918 Peptide chain release factor aRF1 GO:0003747|GO:0005737|GO:0006415 STK_04830 f521e452ce9b33e1bef8072afc736982 349 Gene3D G3DSA:3.30.1330.30 253 349 6.6E-25 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like STK_04830 f521e452ce9b33e1bef8072afc736982 349 Pfam PF03465 eRF1 domain 3 256 348 8.1E-21 T 23-10-2018 IPR005142 eRF1 domain 3 STK_04830 f521e452ce9b33e1bef8072afc736982 349 Pfam PF03464 eRF1 domain 2 120 253 1.5E-42 T 23-10-2018 IPR005141 eRF1 domain 2 STK_04830 f521e452ce9b33e1bef8072afc736982 349 SUPERFAMILY SSF55481 1 116 7.32E-38 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04830 f521e452ce9b33e1bef8072afc736982 349 Pfam PF03463 eRF1 domain 1 10 113 7.0E-5 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like STK_04830 f521e452ce9b33e1bef8072afc736982 349 TIGRFAM TIGR03676 aRF1/eRF1: peptide chain release factor 1, archaeal and eukaryotic forms 1 301 3.2E-123 T 23-10-2018 IPR004403 Peptide chain release factor eRF1/aRF1 GO:0003747|GO:0005737|GO:0006415 Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04830 f521e452ce9b33e1bef8072afc736982 349 SUPERFAMILY SSF55315 253 348 5.65E-23 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like STK_04830 f521e452ce9b33e1bef8072afc736982 349 Gene3D G3DSA:3.30.420.60 117 252 3.0E-43 T 23-10-2018 STK_04830 f521e452ce9b33e1bef8072afc736982 349 SMART SM01194 1 115 4.6E-22 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like STK_04830 f521e452ce9b33e1bef8072afc736982 349 Gene3D G3DSA:3.30.960.10 1 116 2.4E-41 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04830 f521e452ce9b33e1bef8072afc736982 349 SUPERFAMILY SSF53137 118 252 2.14E-38 T 23-10-2018 STK_15200 49dd2f36bf33ef72007b8784227ab20f 223 Pfam PF03483 B3/4 domain 61 212 1.4E-27 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 STK_15200 49dd2f36bf33ef72007b8784227ab20f 223 Gene3D G3DSA:3.50.40.10 59 190 1.5E-7 T 23-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 STK_15200 49dd2f36bf33ef72007b8784227ab20f 223 SMART SM00873 60 213 6.7E-25 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 STK_15200 49dd2f36bf33ef72007b8784227ab20f 223 SUPERFAMILY SSF56037 45 220 5.75E-41 T 23-10-2018 STK_00870 f02052de703f536a1d3d2cf93965a799 360 Gene3D G3DSA:2.40.110.10 125 238 4.1E-35 T 23-10-2018 STK_00870 f02052de703f536a1d3d2cf93965a799 360 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 263 356 7.3E-8 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 STK_00870 f02052de703f536a1d3d2cf93965a799 360 SUPERFAMILY SSF56645 14 242 7.46E-70 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 STK_00870 f02052de703f536a1d3d2cf93965a799 360 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 3 121 4.2E-27 T 23-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 STK_00870 f02052de703f536a1d3d2cf93965a799 360 SUPERFAMILY SSF47203 229 358 2.66E-11 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 STK_00870 f02052de703f536a1d3d2cf93965a799 360 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 205 1.5E-19 T 23-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 STK_00870 f02052de703f536a1d3d2cf93965a799 360 Gene3D G3DSA:1.10.540.10 2 119 3.6E-28 T 23-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 STK_00870 f02052de703f536a1d3d2cf93965a799 360 Gene3D G3DSA:1.20.140.10 258 360 1.7E-13 T 23-10-2018 STK_14380 9ca29773188b5c9f1d1ae5664e2f704d 216 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 5 207 2.8E-32 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 STK_14380 9ca29773188b5c9f1d1ae5664e2f704d 216 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 3 208 23.981 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 STK_14380 9ca29773188b5c9f1d1ae5664e2f704d 216 Pfam PF01813 ATP synthase subunit D 12 203 1.2E-42 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 STK_19985 53a9b42194125e30b249493fb34e520a 75 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 46 9.3E-16 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_19985 53a9b42194125e30b249493fb34e520a 75 SUPERFAMILY SSF89447 3 55 7.67E-14 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily STK_19985 53a9b42194125e30b249493fb34e520a 75 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 6 48 6.7E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_19985 53a9b42194125e30b249493fb34e520a 75 SMART SM00966 5 50 5.9E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_19985 53a9b42194125e30b249493fb34e520a 75 Gene3D G3DSA:2.10.260.10 1 43 1.3E-9 T 23-10-2018 STK_22770 4db68a5cb013f71023906f0609067451 408 ProSitePatterns PS00885 EPSP synthase signature 2. 318 336 - T 23-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 STK_22770 4db68a5cb013f71023906f0609067451 408 Gene3D G3DSA:3.65.10.10 12 394 5.4E-85 T 23-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 STK_22770 4db68a5cb013f71023906f0609067451 408 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 398 4.5E-67 T 23-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 STK_22770 4db68a5cb013f71023906f0609067451 408 SUPERFAMILY SSF55205 2 403 4.25E-78 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 STK_22770 4db68a5cb013f71023906f0609067451 408 Gene3D G3DSA:3.65.10.10 20 222 5.4E-85 T 23-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 STK_22770 4db68a5cb013f71023906f0609067451 408 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 12 402 1.7E-90 T 23-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 STK_22770 4db68a5cb013f71023906f0609067451 408 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 8 404 28.431 T 23-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 STK_22770 4db68a5cb013f71023906f0609067451 408 PIRSF PIRSF000505 1 407 1.3E-98 T 23-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 STK_23480 51e4aecbc06b2c55a9bdecf462e18e34 133 Gene3D G3DSA:3.10.580.10 1 133 3.4E-45 T 23-10-2018 STK_23480 51e4aecbc06b2c55a9bdecf462e18e34 133 SMART SM00116 76 124 8.3E-13 T 23-10-2018 IPR000644 CBS domain STK_23480 51e4aecbc06b2c55a9bdecf462e18e34 133 SMART SM00116 13 60 1.5E-11 T 23-10-2018 IPR000644 CBS domain STK_23480 51e4aecbc06b2c55a9bdecf462e18e34 133 SUPERFAMILY SSF54631 2 123 3.41E-37 T 23-10-2018 STK_23480 51e4aecbc06b2c55a9bdecf462e18e34 133 Pfam PF00571 CBS domain 6 59 4.5E-14 T 23-10-2018 IPR000644 CBS domain STK_23480 51e4aecbc06b2c55a9bdecf462e18e34 133 Pfam PF00571 CBS domain 70 124 3.4E-15 T 23-10-2018 IPR000644 CBS domain STK_06750 99ba1cf40f4d37839057e0d4334a4b54 188 Gene3D G3DSA:3.60.15.10 4 133 3.5E-17 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_06750 99ba1cf40f4d37839057e0d4334a4b54 188 SUPERFAMILY SSF56281 13 153 6.92E-19 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_04085 04176a4b94f89e7cb3f88bdb8607377c 87 Gene3D G3DSA:3.40.1800.40 30 84 2.1E-10 T 23-10-2018 IPR038562 Ribosomal protein L34Ae superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04085 04176a4b94f89e7cb3f88bdb8607377c 87 PRINTS PR01250 Ribosomal protein L34 signature 37 47 8.9E-18 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04085 04176a4b94f89e7cb3f88bdb8607377c 87 PRINTS PR01250 Ribosomal protein L34 signature 6 19 8.9E-18 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04085 04176a4b94f89e7cb3f88bdb8607377c 87 PRINTS PR01250 Ribosomal protein L34 signature 54 76 8.9E-18 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04085 04176a4b94f89e7cb3f88bdb8607377c 87 PRINTS PR01250 Ribosomal protein L34 signature 19 36 8.9E-18 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04085 04176a4b94f89e7cb3f88bdb8607377c 87 ProSitePatterns PS01145 Ribosomal protein L34e signature. 8 21 - T 23-10-2018 IPR018065 Ribosomal protein L34e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04085 04176a4b94f89e7cb3f88bdb8607377c 87 Hamap MF_00349 50S ribosomal protein L34e [rpl34e]. 2 85 25.915 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04085 04176a4b94f89e7cb3f88bdb8607377c 87 Pfam PF01199 Ribosomal protein L34e 3 82 1.7E-18 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_18760 ebb5ed511fdf505bc401b768848a0ec9 121 Gene3D G3DSA:3.40.1260.10 1 121 6.7E-45 T 23-10-2018 IPR027396 DsrEFH-like STK_18760 ebb5ed511fdf505bc401b768848a0ec9 121 SUPERFAMILY SSF75169 5 117 1.85E-16 T 23-10-2018 IPR027396 DsrEFH-like STK_18760 ebb5ed511fdf505bc401b768848a0ec9 121 Pfam PF13686 DsrE/DsrF/DrsH-like family 2 115 2.2E-20 T 23-10-2018 IPR032836 DsrE2-like family STK_07530 a86a381375930461f55d809566c0cca0 149 Pfam PF13456 Reverse transcriptase-like 16 129 2.9E-17 T 23-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 STK_07530 a86a381375930461f55d809566c0cca0 149 SUPERFAMILY SSF53098 5 128 7.71E-22 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily STK_07530 a86a381375930461f55d809566c0cca0 149 Gene3D G3DSA:3.30.420.10 1 149 1.5E-43 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 STK_10110 631beca40105fa96c9851c416a10c717 433 SUPERFAMILY SSF51338 2 422 3.11E-17 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_10110 631beca40105fa96c9851c416a10c717 433 Gene3D G3DSA:3.20.20.140 48 405 7.0E-112 T 23-10-2018 STK_10110 631beca40105fa96c9851c416a10c717 433 Pfam PF01979 Amidohydrolase family 44 417 9.2E-18 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 STK_10110 631beca40105fa96c9851c416a10c717 433 Gene3D G3DSA:2.30.40.10 2 425 7.0E-112 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_10110 631beca40105fa96c9851c416a10c717 433 SUPERFAMILY SSF51556 49 368 2.27E-71 T 23-10-2018 IPR032466 Metal-dependent hydrolase STK_14310 9aaf68972a80deb0f03f4bd4e1b9d9ee 306 Pfam PF04104 Eukaryotic and archaeal DNA primase, large subunit 139 288 7.2E-10 T 23-10-2018 IPR007238 DNA primase large subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 STK_14310 9aaf68972a80deb0f03f4bd4e1b9d9ee 306 SUPERFAMILY SSF140914 4 226 2.22E-49 T 23-10-2018 STK_14310 9aaf68972a80deb0f03f4bd4e1b9d9ee 306 Hamap MF_00701 DNA primase large subunit PriL [priL]. 7 306 23.855 T 23-10-2018 IPR023642 DNA primase large subunit PriL GO:0003896 STK_23500 f997b89b7ee0c986f3dc96b2f426b84c 272 Pfam PF01791 DeoC/LacD family aldolase 19 243 6.8E-36 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 STK_23500 f997b89b7ee0c986f3dc96b2f426b84c 272 SUPERFAMILY SSF51569 3 260 1.46E-60 T 23-10-2018 STK_23500 f997b89b7ee0c986f3dc96b2f426b84c 272 Gene3D G3DSA:3.20.20.70 1 272 9.0E-73 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_23500 f997b89b7ee0c986f3dc96b2f426b84c 272 SMART SM01133 17 244 3.5E-29 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 STK_23500 f997b89b7ee0c986f3dc96b2f426b84c 272 PIRSF PIRSF038992 1 272 9.4E-82 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 STK_07410 c7667d27efb368f6d48908238383f3a1 124 Gene3D G3DSA:3.40.50.1010 1 121 7.1E-12 T 23-10-2018 STK_07410 c7667d27efb368f6d48908238383f3a1 124 SUPERFAMILY SSF88723 3 111 3.92E-15 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_07410 c7667d27efb368f6d48908238383f3a1 124 Pfam PF01850 PIN domain 4 110 3.3E-14 T 23-10-2018 IPR002716 PIN domain STK_01140 7434c31f54ffbdffd0f84309c257cbfc 414 SMART SM00919 155 384 1.7E-100 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 STK_01140 7434c31f54ffbdffd0f84309c257cbfc 414 SUPERFAMILY SSF53223 5 153 1.01E-50 T 23-10-2018 STK_01140 7434c31f54ffbdffd0f84309c257cbfc 414 SMART SM01274 10 143 2.5E-70 T 23-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 STK_01140 7434c31f54ffbdffd0f84309c257cbfc 414 Gene3D G3DSA:3.40.50.720 153 413 2.6E-84 T 23-10-2018 STK_01140 7434c31f54ffbdffd0f84309c257cbfc 414 PIRSF PIRSF000106 22 411 6.4E-81 T 23-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 STK_01140 7434c31f54ffbdffd0f84309c257cbfc 414 SUPERFAMILY SSF51735 155 409 2.63E-70 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_01140 7434c31f54ffbdffd0f84309c257cbfc 414 Pfam PF00390 Malic enzyme, N-terminal domain 10 142 8.5E-23 T 23-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 STK_01140 7434c31f54ffbdffd0f84309c257cbfc 414 Pfam PF03949 Malic enzyme, NAD binding domain 156 383 1.3E-27 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 STK_01140 7434c31f54ffbdffd0f84309c257cbfc 414 Gene3D G3DSA:3.40.50.10380 1 152 1.6E-64 T 23-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 STK_02700 f903df86987d82fd475a761a2eea217c 194 SUPERFAMILY SSF47973 14 194 4.45E-64 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily STK_02700 f903df86987d82fd475a761a2eea217c 194 TIGRFAM TIGR01028 uS7_euk_arch: ribosomal protein uS7 11 194 2.9E-85 T 23-10-2018 IPR005716 Ribosomal protein S5/S7, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_02700 f903df86987d82fd475a761a2eea217c 194 Hamap MF_00480_A 30S ribosomal protein S7 [rpsG]. 11 194 41.836 T 23-10-2018 IPR026018 Ribosomal protein S7, archaeal STK_02700 f903df86987d82fd475a761a2eea217c 194 ProSitePatterns PS00052 Ribosomal protein S7 signature. 60 86 - T 23-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_02700 f903df86987d82fd475a761a2eea217c 194 PIRSF PIRSF002122 2 194 2.6E-47 T 23-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 STK_02700 f903df86987d82fd475a761a2eea217c 194 Gene3D G3DSA:1.10.455.10 2 194 2.2E-86 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily STK_02700 f903df86987d82fd475a761a2eea217c 194 Pfam PF00177 Ribosomal protein S7p/S5e 53 194 1.8E-44 T 23-10-2018 IPR023798 Ribosomal protein S7 domain STK_16720 02b2f8f01ab8183e19208319b9d90875 303 SUPERFAMILY SSF52540 2 221 4.77E-54 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_16720 02b2f8f01ab8183e19208319b9d90875 303 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 STK_16720 02b2f8f01ab8183e19208319b9d90875 303 Pfam PF00005 ABC transporter 17 160 8.2E-25 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_16720 02b2f8f01ab8183e19208319b9d90875 303 Gene3D G3DSA:3.40.50.300 1 240 7.0E-55 T 23-10-2018 STK_16720 02b2f8f01ab8183e19208319b9d90875 303 SMART SM00382 26 209 0.0031 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_25590 005a2334440fc85eeb972eb8288b6efe 98 Pfam PF08666 SAF domain 11 89 1.4E-13 T 23-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 STK_25590 005a2334440fc85eeb972eb8288b6efe 98 SMART SM00858 11 89 7.1E-17 T 23-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 STK_25590 005a2334440fc85eeb972eb8288b6efe 98 Gene3D G3DSA:3.90.1210.30 3 91 2.3E-27 T 23-10-2018 STK_20940 9330e7255d652f604a5b508577fdd3f8 391 SUPERFAMILY SSF51735 2 181 4.59E-58 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_20940 9330e7255d652f604a5b508577fdd3f8 391 SUPERFAMILY SSF48179 185 287 7.23E-24 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 STK_20940 9330e7255d652f604a5b508577fdd3f8 391 SUPERFAMILY SSF48179 303 391 1.96E-23 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 STK_20940 9330e7255d652f604a5b508577fdd3f8 391 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 181 1.1E-65 T 23-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 STK_20940 9330e7255d652f604a5b508577fdd3f8 391 Gene3D G3DSA:1.10.1040.10 304 391 9.0E-26 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 STK_20940 9330e7255d652f604a5b508577fdd3f8 391 Gene3D G3DSA:1.10.1040.10 188 298 2.9E-25 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 STK_20940 9330e7255d652f604a5b508577fdd3f8 391 Gene3D G3DSA:3.40.50.720 3 187 3.0E-67 T 23-10-2018 STK_20940 9330e7255d652f604a5b508577fdd3f8 391 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 280 8.1E-25 T 23-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 STK_20940 9330e7255d652f604a5b508577fdd3f8 391 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 304 391 2.2E-21 T 23-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 STK_21260 3bfe66c6b3f0cc016a13f30e8b0f9674 288 Gene3D G3DSA:3.40.190.10 1 93 7.5E-7 T 23-10-2018 STK_21260 3bfe66c6b3f0cc016a13f30e8b0f9674 288 Gene3D G3DSA:3.40.190.10 107 288 8.8E-29 T 23-10-2018 STK_21260 3bfe66c6b3f0cc016a13f30e8b0f9674 288 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 3 280 29.823 T 23-10-2018 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 STK_21260 3bfe66c6b3f0cc016a13f30e8b0f9674 288 SUPERFAMILY SSF53850 4 279 2.04E-52 T 23-10-2018 STK_21260 3bfe66c6b3f0cc016a13f30e8b0f9674 288 Pfam PF02621 Menaquinone biosynthesis 4 274 1.4E-65 T 23-10-2018 IPR003773 Menaquinone biosynthesis enzyme STK_13900 5d0edcbaa895a1e177b79faf7e8ceede 349 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 185 195 7.2E-19 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase STK_13900 5d0edcbaa895a1e177b79faf7e8ceede 349 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 251 263 7.2E-19 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase STK_13900 5d0edcbaa895a1e177b79faf7e8ceede 349 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 156 170 7.2E-19 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase STK_13900 5d0edcbaa895a1e177b79faf7e8ceede 349 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 298 314 7.2E-19 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase STK_13900 5d0edcbaa895a1e177b79faf7e8ceede 349 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 330 347 7.2E-19 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase STK_13900 5d0edcbaa895a1e177b79faf7e8ceede 349 Gene3D G3DSA:2.30.130.10 81 139 1.4E-5 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 STK_13900 5d0edcbaa895a1e177b79faf7e8ceede 349 SUPERFAMILY SSF53335 4 348 7.54E-51 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_13900 5d0edcbaa895a1e177b79faf7e8ceede 349 Gene3D G3DSA:3.40.50.150 165 348 2.5E-48 T 23-10-2018 STK_13900 5d0edcbaa895a1e177b79faf7e8ceede 349 SUPERFAMILY SSF88697 83 133 2.42E-5 T 23-10-2018 IPR015947 PUA-like superfamily STK_13900 5d0edcbaa895a1e177b79faf7e8ceede 349 Pfam PF01189 16S rRNA methyltransferase RsmB/F 174 319 2.1E-35 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 STK_21720 f072350be8e1167532e4ab454317e8b5 560 Pfam PF00920 Dehydratase family 37 556 2.8E-213 T 23-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 STK_21720 f072350be8e1167532e4ab454317e8b5 560 SUPERFAMILY SSF143975 4 380 3.79E-137 T 23-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 STK_21720 f072350be8e1167532e4ab454317e8b5 560 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 125 135 - T 23-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 STK_21720 f072350be8e1167532e4ab454317e8b5 560 SUPERFAMILY SSF52016 381 558 5.26E-61 T 23-10-2018 STK_21720 f072350be8e1167532e4ab454317e8b5 560 Gene3D G3DSA:3.50.30.80 381 530 2.2E-55 T 23-10-2018 STK_21720 f072350be8e1167532e4ab454317e8b5 560 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 20 558 1.6E-221 T 23-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 STK_21720 f072350be8e1167532e4ab454317e8b5 560 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 7 559 46.98 T 23-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 STK_21720 f072350be8e1167532e4ab454317e8b5 560 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 467 478 - T 23-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 STK_00880 12c725734cf5a14a0030d5b3d379002c 271 SUPERFAMILY SSF103481 175 269 6.54E-11 T 23-10-2018 STK_00880 12c725734cf5a14a0030d5b3d379002c 271 Pfam PF00892 EamA-like transporter family 8 128 1.2E-6 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 STK_00880 12c725734cf5a14a0030d5b3d379002c 271 Pfam PF00892 EamA-like transporter family 137 269 9.5E-17 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 STK_00650 b898e9ad6113e30c5afb297d401f03ce 465 Gene3D G3DSA:1.20.1250.20 19 464 7.2E-76 T 23-10-2018 STK_00650 b898e9ad6113e30c5afb297d401f03ce 465 Pfam PF00083 Sugar (and other) transporter 60 461 2.3E-47 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 STK_00650 b898e9ad6113e30c5afb297d401f03ce 465 ProSitePatterns PS00217 Sugar transport proteins signature 2. 124 149 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 STK_00650 b898e9ad6113e30c5afb297d401f03ce 465 SUPERFAMILY SSF103473 1 461 6.67E-75 T 23-10-2018 IPR036259 MFS transporter superfamily STK_13180 11f00d02c1bfc1e885b37d972b19b831 427 SUPERFAMILY SSF110849 36 124 2.62E-12 T 23-10-2018 IPR036086 ParB/Sulfiredoxin superfamily STK_13180 11f00d02c1bfc1e885b37d972b19b831 427 Pfam PF02195 ParB-like nuclease domain 14 88 3.9E-6 T 23-10-2018 IPR003115 ParB/Sulfiredoxin STK_13180 11f00d02c1bfc1e885b37d972b19b831 427 Gene3D G3DSA:3.90.1530.10 6 95 1.9E-5 T 23-10-2018 STK_13180 11f00d02c1bfc1e885b37d972b19b831 427 SMART SM00470 12 102 3.2E-5 T 23-10-2018 IPR003115 ParB/Sulfiredoxin STK_03210 802d8c2bb4368e318df06d9a36c7c026 552 Gene3D G3DSA:3.50.7.10 224 375 8.1E-212 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily STK_03210 802d8c2bb4368e318df06d9a36c7c026 552 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 68 84 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_03210 802d8c2bb4368e318df06d9a36c7c026 552 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 414 426 3.6E-29 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_03210 802d8c2bb4368e318df06d9a36c7c026 552 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 380 402 3.6E-29 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_03210 802d8c2bb4368e318df06d9a36c7c026 552 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 96 115 3.6E-29 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_03210 802d8c2bb4368e318df06d9a36c7c026 552 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 44 60 3.6E-29 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_03210 802d8c2bb4368e318df06d9a36c7c026 552 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 66 84 3.6E-29 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_03210 802d8c2bb4368e318df06d9a36c7c026 552 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 96 104 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_03210 802d8c2bb4368e318df06d9a36c7c026 552 SUPERFAMILY SSF48592 24 531 3.09E-86 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily STK_03210 802d8c2bb4368e318df06d9a36c7c026 552 Gene3D G3DSA:3.30.260.10 153 411 8.1E-212 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily STK_03210 802d8c2bb4368e318df06d9a36c7c026 552 SUPERFAMILY SSF52029 219 385 4.93E-61 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily STK_03210 802d8c2bb4368e318df06d9a36c7c026 552 Gene3D G3DSA:1.10.560.10 35 528 8.1E-212 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily STK_03210 802d8c2bb4368e318df06d9a36c7c026 552 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 47 59 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 STK_03210 802d8c2bb4368e318df06d9a36c7c026 552 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 15 532 1.0E-252 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 STK_03210 802d8c2bb4368e318df06d9a36c7c026 552 Pfam PF00118 TCP-1/cpn60 chaperonin family 43 533 1.2E-177 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 STK_03210 802d8c2bb4368e318df06d9a36c7c026 552 SUPERFAMILY SSF54849 155 411 6.41E-28 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily STK_14590 4b395e8949b063bd303fa39971c89669 285 Gene3D G3DSA:3.30.70.120 213 285 2.5E-20 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal STK_14590 4b395e8949b063bd303fa39971c89669 285 Gene3D G3DSA:3.40.190.10 2 193 9.7E-66 T 23-10-2018 STK_14590 4b395e8949b063bd303fa39971c89669 285 SUPERFAMILY SSF54913 213 284 1.22E-17 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta STK_14590 4b395e8949b063bd303fa39971c89669 285 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 1 184 6.1E-64 T 23-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 STK_14590 4b395e8949b063bd303fa39971c89669 285 Pfam PF01634 ATP phosphoribosyltransferase 49 205 2.1E-49 T 23-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 STK_14590 4b395e8949b063bd303fa39971c89669 285 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 186 284 1.3E-29 T 23-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 STK_14590 4b395e8949b063bd303fa39971c89669 285 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 143 164 - T 23-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 STK_14590 4b395e8949b063bd303fa39971c89669 285 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 285 32.278 T 23-10-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 STK_14590 4b395e8949b063bd303fa39971c89669 285 SUPERFAMILY SSF53850 1 210 1.71E-62 T 23-10-2018 STK_14590 4b395e8949b063bd303fa39971c89669 285 Pfam PF08029 HisG, C-terminal domain 210 282 2.1E-21 T 23-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 STK_14590 4b395e8949b063bd303fa39971c89669 285 Gene3D G3DSA:3.40.190.10 88 178 9.7E-66 T 23-10-2018 STK_04360 fb69a793fc88cb8d742900d5ccf3fa2e 241 Gene3D G3DSA:1.10.150.520 24 111 5.1E-43 T 23-10-2018 STK_04360 fb69a793fc88cb8d742900d5ccf3fa2e 241 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 90 208 1.4E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 STK_04360 fb69a793fc88cb8d742900d5ccf3fa2e 241 Gene3D G3DSA:3.40.50.1000 11 237 5.1E-43 T 23-10-2018 IPR023214 HAD superfamily STK_04360 fb69a793fc88cb8d742900d5ccf3fa2e 241 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 214 4.3E-24 T 23-10-2018 STK_04360 fb69a793fc88cb8d742900d5ccf3fa2e 241 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 6.9E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 STK_04360 fb69a793fc88cb8d742900d5ccf3fa2e 241 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 123 136 6.9E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 STK_04360 fb69a793fc88cb8d742900d5ccf3fa2e 241 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 203 216 6.9E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 STK_04360 fb69a793fc88cb8d742900d5ccf3fa2e 241 SUPERFAMILY SSF56784 9 241 6.67E-42 T 23-10-2018 IPR036412 HAD-like superfamily STK_00480 bc4b28bd18c7682f15153ed0da367592 254 Gene3D G3DSA:1.10.12.10 197 254 3.0E-17 T 23-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal STK_00480 bc4b28bd18c7682f15153ed0da367592 254 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 253 4.0E-63 T 23-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 STK_00480 bc4b28bd18c7682f15153ed0da367592 254 SUPERFAMILY SSF52096 4 254 9.16E-80 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily STK_00480 bc4b28bd18c7682f15153ed0da367592 254 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 95 115 - T 23-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 STK_00480 bc4b28bd18c7682f15153ed0da367592 254 Gene3D G3DSA:3.90.226.10 1 195 2.3E-62 T 23-10-2018 STK_18620 f5a6e388806e9c58f1546aea00ecec8f 233 Pfam PF11485 Protein of unknown function (DUF3211) 1 132 3.4E-8 T 23-10-2018 IPR021578 Protein of unknown function DUF3211 STK_18620 f5a6e388806e9c58f1546aea00ecec8f 233 Gene3D G3DSA:3.30.530.20 1 148 7.2E-7 T 23-10-2018 IPR023393 START-like domain superfamily STK_18620 f5a6e388806e9c58f1546aea00ecec8f 233 SUPERFAMILY SSF55961 1 134 1.84E-11 T 23-10-2018 STK_10380 2c3a42699b5e8cb6112db8432743cc05 626 SUPERFAMILY SSF52540 143 615 1.94E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_10380 2c3a42699b5e8cb6112db8432743cc05 626 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 507 576 7.0E-5 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_10380 2c3a42699b5e8cb6112db8432743cc05 626 Gene3D G3DSA:3.40.50.300 156 261 2.7E-11 T 23-10-2018 STK_10380 2c3a42699b5e8cb6112db8432743cc05 626 Pfam PF01935 Domain of unknown function DUF87 173 248 2.1E-9 T 23-10-2018 IPR002789 Helicase HerA, central domain STK_10380 2c3a42699b5e8cb6112db8432743cc05 626 Gene3D G3DSA:3.40.50.300 429 622 9.1E-17 T 23-10-2018 STK_08460 ec0d57d5dd842180a1ed59118c583a2f 179 Pfam PF05942 Archaeal PaREP1/PaREP8 family 15 137 2.8E-26 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_00960 0b6ff22502069a6947eb3e81d367833a 373 SUPERFAMILY SSF53901 236 359 1.73E-24 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_00960 0b6ff22502069a6947eb3e81d367833a 373 PIRSF PIRSF000429 1 370 1.7E-41 T 23-10-2018 IPR002155 Thiolase GO:0016747 STK_00960 0b6ff22502069a6947eb3e81d367833a 373 Gene3D G3DSA:3.40.47.10 1 373 2.9E-121 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_00960 0b6ff22502069a6947eb3e81d367833a 373 Pfam PF02803 Thiolase, C-terminal domain 248 349 2.5E-5 T 23-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 STK_00960 0b6ff22502069a6947eb3e81d367833a 373 SUPERFAMILY SSF53901 2 214 5.51E-28 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_00960 0b6ff22502069a6947eb3e81d367833a 373 Pfam PF00108 Thiolase, N-terminal domain 2 211 1.5E-21 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 STK_03930 f1bc642383dc08c2b72cc89c6c775e50 154 PIRSF PIRSF015750 1 154 1.1E-74 T 23-10-2018 IPR006399 Riboflavin synthase, archaeal GO:0004746|GO:0009231 KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 STK_03930 f1bc642383dc08c2b72cc89c6c775e50 154 Gene3D G3DSA:3.40.50.960 1 154 6.5E-49 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 STK_03930 f1bc642383dc08c2b72cc89c6c775e50 154 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 15 92 4.8E-10 T 23-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 STK_03930 f1bc642383dc08c2b72cc89c6c775e50 154 TIGRFAM TIGR01506 ribC_arch: riboflavin synthase 4 153 1.0E-62 T 23-10-2018 IPR006399 Riboflavin synthase, archaeal GO:0004746|GO:0009231 KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 STK_03930 f1bc642383dc08c2b72cc89c6c775e50 154 SUPERFAMILY SSF52121 3 129 1.96E-24 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 STK_10850 ceaeda5e76cfb29336c6f6dfc6fd88ec 118 Pfam PF05168 HEPN domain 2 117 5.0E-25 T 23-10-2018 IPR007842 HEPN domain STK_10850 ceaeda5e76cfb29336c6f6dfc6fd88ec 118 SMART SM00748 5 114 1.8E-38 T 23-10-2018 IPR007842 HEPN domain STK_10850 ceaeda5e76cfb29336c6f6dfc6fd88ec 118 Gene3D G3DSA:1.20.120.330 1 118 3.8E-23 T 23-10-2018 STK_10850 ceaeda5e76cfb29336c6f6dfc6fd88ec 118 SUPERFAMILY SSF81593 4 117 3.92E-28 T 23-10-2018 STK_23710 aa001577d932a823b38e5376ca934bb5 131 SMART SM00116 10 58 2.9E-9 T 23-10-2018 IPR000644 CBS domain STK_23710 aa001577d932a823b38e5376ca934bb5 131 SMART SM00116 74 122 1.2E-10 T 23-10-2018 IPR000644 CBS domain STK_23710 aa001577d932a823b38e5376ca934bb5 131 Pfam PF00571 CBS domain 3 58 7.1E-13 T 23-10-2018 IPR000644 CBS domain STK_23710 aa001577d932a823b38e5376ca934bb5 131 Pfam PF00571 CBS domain 67 121 4.3E-15 T 23-10-2018 IPR000644 CBS domain STK_23710 aa001577d932a823b38e5376ca934bb5 131 SUPERFAMILY SSF54631 2 121 5.31E-35 T 23-10-2018 STK_23710 aa001577d932a823b38e5376ca934bb5 131 Gene3D G3DSA:3.10.580.10 1 127 1.1E-37 T 23-10-2018 STK_23910 e002de6557c8d288d0ae3bb70032ed83 1133 Gene3D G3DSA:3.40.228.10 350 531 5.8E-32 T 23-10-2018 STK_23910 e002de6557c8d288d0ae3bb70032ed83 1133 Pfam PF01568 Molydopterin dinucleotide binding domain 1013 1098 4.1E-13 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 STK_23910 e002de6557c8d288d0ae3bb70032ed83 1133 Gene3D G3DSA:3.40.50.740 164 349 4.0E-17 T 23-10-2018 STK_23910 e002de6557c8d288d0ae3bb70032ed83 1133 SUPERFAMILY SSF53706 16 889 2.28E-70 T 23-10-2018 STK_23910 e002de6557c8d288d0ae3bb70032ed83 1133 Gene3D G3DSA:2.40.40.20 983 1115 5.1E-41 T 23-10-2018 STK_23910 e002de6557c8d288d0ae3bb70032ed83 1133 Gene3D G3DSA:3.30.200.50 12 155 4.4E-23 T 23-10-2018 STK_23910 e002de6557c8d288d0ae3bb70032ed83 1133 SUPERFAMILY SSF50692 985 1110 2.49E-24 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily STK_18400 0da54281d0687e93eb555fa59e7f8907 1436 Gene3D G3DSA:3.40.50.740 41 321 2.2E-30 T 23-10-2018 STK_18400 0da54281d0687e93eb555fa59e7f8907 1436 SUPERFAMILY SSF53706 6 829 8.82E-116 T 23-10-2018 STK_18400 0da54281d0687e93eb555fa59e7f8907 1436 SUPERFAMILY SSF50692 1173 1335 8.59E-13 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily STK_18400 0da54281d0687e93eb555fa59e7f8907 1436 Gene3D G3DSA:2.40.40.20 1152 1326 3.7E-8 T 23-10-2018 STK_18400 0da54281d0687e93eb555fa59e7f8907 1436 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 6 25 0.0015 T 23-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal STK_24930 533c3540ae2fa67c7e0bdbf472ea7c79 139 SUPERFAMILY SSF81593 5 125 9.81E-43 T 23-10-2018 STK_24930 533c3540ae2fa67c7e0bdbf472ea7c79 139 SMART SM00748 11 118 7.8E-44 T 23-10-2018 IPR007842 HEPN domain STK_24930 533c3540ae2fa67c7e0bdbf472ea7c79 139 Pfam PF05168 HEPN domain 8 125 3.8E-34 T 23-10-2018 IPR007842 HEPN domain STK_24930 533c3540ae2fa67c7e0bdbf472ea7c79 139 Gene3D G3DSA:1.20.120.330 3 128 7.7E-38 T 23-10-2018 STK_00980 852bdd80071be3fadd51460ba2c5343d 168 SUPERFAMILY SSF53223 1 111 7.04E-15 T 23-10-2018 STK_00980 852bdd80071be3fadd51460ba2c5343d 168 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 1 85 1.3E-6 T 23-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 STK_00980 852bdd80071be3fadd51460ba2c5343d 168 Gene3D G3DSA:3.40.50.10860 1 101 9.3E-9 T 23-10-2018 STK_10060 dc1effee138e3941f18ed6efd46ca147 473 PRINTS PR01035 Tetracycline resistance protein signature 101 122 3.3E-5 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 STK_10060 dc1effee138e3941f18ed6efd46ca147 473 PRINTS PR01035 Tetracycline resistance protein signature 43 62 3.3E-5 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 STK_10060 dc1effee138e3941f18ed6efd46ca147 473 PRINTS PR01035 Tetracycline resistance protein signature 74 98 3.3E-5 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 STK_10060 dc1effee138e3941f18ed6efd46ca147 473 PRINTS PR01035 Tetracycline resistance protein signature 131 153 3.3E-5 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 STK_10060 dc1effee138e3941f18ed6efd46ca147 473 Gene3D G3DSA:1.20.1720.10 7 211 2.5E-47 T 23-10-2018 STK_10060 dc1effee138e3941f18ed6efd46ca147 473 SUPERFAMILY SSF103473 6 461 1.15E-67 T 23-10-2018 IPR036259 MFS transporter superfamily STK_10060 dc1effee138e3941f18ed6efd46ca147 473 Gene3D G3DSA:1.20.1250.20 256 464 6.0E-16 T 23-10-2018 STK_10060 dc1effee138e3941f18ed6efd46ca147 473 Pfam PF07690 Major Facilitator Superfamily 15 281 1.0E-39 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_02600 61ed2643f1bd6904df5656375fa13ac3 298 Gene3D G3DSA:1.10.4200.10 32 279 6.3E-34 T 23-10-2018 STK_02600 61ed2643f1bd6904df5656375fa13ac3 298 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 17 272 4.2E-39 T 23-10-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 STK_15870 021681a0efbe511c428bfaa337b8cdaa 256 SUPERFAMILY SSF46785 132 180 3.69E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_15870 021681a0efbe511c428bfaa337b8cdaa 256 Gene3D G3DSA:1.10.10.10 128 175 1.8E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_15870 021681a0efbe511c428bfaa337b8cdaa 256 SUPERFAMILY SSF46785 1 60 2.58E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_15870 021681a0efbe511c428bfaa337b8cdaa 256 SMART SM00344 1 106 7.9E-4 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 STK_15870 021681a0efbe511c428bfaa337b8cdaa 256 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 1.8E-14 T 23-10-2018 STK_15870 021681a0efbe511c428bfaa337b8cdaa 256 Pfam PF13412 Winged helix-turn-helix DNA-binding 132 175 2.8E-8 T 23-10-2018 STK_15870 021681a0efbe511c428bfaa337b8cdaa 256 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 9.2E-9 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_15870 021681a0efbe511c428bfaa337b8cdaa 256 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 9.2E-9 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_15870 021681a0efbe511c428bfaa337b8cdaa 256 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 9.2E-9 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_15870 021681a0efbe511c428bfaa337b8cdaa 256 Gene3D G3DSA:1.10.10.10 1 51 8.7E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_11160 f8e80bc76535453415c9e5d1c0b7c24c 490 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 284 295 - T 23-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 STK_11160 f8e80bc76535453415c9e5d1c0b7c24c 490 Gene3D G3DSA:3.40.309.10 259 460 2.6E-146 T 23-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 STK_11160 f8e80bc76535453415c9e5d1c0b7c24c 490 Gene3D G3DSA:3.40.605.10 31 468 2.6E-146 T 23-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 STK_11160 f8e80bc76535453415c9e5d1c0b7c24c 490 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 14 490 5.4E-160 T 23-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 STK_11160 f8e80bc76535453415c9e5d1c0b7c24c 490 SUPERFAMILY SSF53720 12 490 2.62E-144 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 STK_11160 f8e80bc76535453415c9e5d1c0b7c24c 490 Pfam PF00171 Aldehyde dehydrogenase family 30 486 4.3E-144 T 23-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 STK_13085 6cc26d39d17c1ea53ee2b3fba76ef5b2 97 SUPERFAMILY SSF46785 6 92 8.84E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_13085 6cc26d39d17c1ea53ee2b3fba76ef5b2 97 Gene3D G3DSA:1.10.10.10 3 95 6.4E-13 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_13085 6cc26d39d17c1ea53ee2b3fba76ef5b2 97 Pfam PF13463 Winged helix DNA-binding domain 14 79 1.4E-6 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 STK_11410 e600ca5f2f0138656657dee5f10f61e9 125 SUPERFAMILY SSF81593 9 124 8.63E-31 T 23-10-2018 STK_11410 e600ca5f2f0138656657dee5f10f61e9 125 Gene3D G3DSA:1.20.120.330 3 125 1.5E-25 T 23-10-2018 STK_11410 e600ca5f2f0138656657dee5f10f61e9 125 SMART SM00748 11 121 2.6E-43 T 23-10-2018 IPR007842 HEPN domain STK_11410 e600ca5f2f0138656657dee5f10f61e9 125 Pfam PF05168 HEPN domain 8 124 9.7E-32 T 23-10-2018 IPR007842 HEPN domain STK_17790 b6179889deafef73bcac2e4dcec5cfaa 343 Pfam PF02371 Transposase IS116/IS110/IS902 family 222 307 1.3E-24 T 23-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 STK_22210 baa569465c3c2798951bb8bc6e3e0118 162 Gene3D G3DSA:1.20.120.1200 6 160 8.5E-9 T 23-10-2018 STK_22210 baa569465c3c2798951bb8bc6e3e0118 162 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 19 158 8.0E-15 T 23-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_09380 dd34c3b5e22f9b21fd14bd1962ebe487 245 Pfam PF00106 short chain dehydrogenase 2 177 1.6E-45 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_09380 dd34c3b5e22f9b21fd14bd1962ebe487 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 65 76 2.1E-11 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_09380 dd34c3b5e22f9b21fd14bd1962ebe487 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 157 2.1E-11 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_09380 dd34c3b5e22f9b21fd14bd1962ebe487 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 118 126 2.1E-11 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_09380 dd34c3b5e22f9b21fd14bd1962ebe487 245 Gene3D G3DSA:3.40.50.720 1 243 1.5E-56 T 23-10-2018 STK_09380 dd34c3b5e22f9b21fd14bd1962ebe487 245 SUPERFAMILY SSF51735 2 220 9.89E-58 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_09380 dd34c3b5e22f9b21fd14bd1962ebe487 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.3E-28 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_09380 dd34c3b5e22f9b21fd14bd1962ebe487 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 176 1.3E-28 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_09380 dd34c3b5e22f9b21fd14bd1962ebe487 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 112 128 1.3E-28 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_09380 dd34c3b5e22f9b21fd14bd1962ebe487 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 157 1.3E-28 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_09380 dd34c3b5e22f9b21fd14bd1962ebe487 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 65 76 1.3E-28 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_19190 5236bcbbb0c7a34ddfeda5632b6a1224 412 Pfam PF13173 AAA domain 48 166 1.3E-28 T 23-10-2018 STK_19190 5236bcbbb0c7a34ddfeda5632b6a1224 412 SUPERFAMILY SSF52540 23 199 2.89E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_19190 5236bcbbb0c7a34ddfeda5632b6a1224 412 Pfam PF13635 Domain of unknown function (DUF4143) 241 353 4.3E-10 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 STK_19150 688a6549366812a4185265d73e6ccf8d 353 SUPERFAMILY SSF53850 42 335 2.1E-17 T 23-10-2018 STK_19150 688a6549366812a4185265d73e6ccf8d 353 Pfam PF01547 Bacterial extracellular solute-binding protein 55 201 1.6E-6 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein STK_19150 688a6549366812a4185265d73e6ccf8d 353 Gene3D G3DSA:3.40.190.10 36 351 4.1E-21 T 23-10-2018 STK_05850 7c5f8b1e43964b85f8625784529b4567 220 Gene3D G3DSA:3.60.21.10 1 215 1.1E-13 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like STK_05850 7c5f8b1e43964b85f8625784529b4567 220 PIRSF PIRSF008292 1 220 8.7E-98 T 23-10-2018 IPR016538 Uncharacterised conserved protein UCP008292 STK_05850 7c5f8b1e43964b85f8625784529b4567 220 Pfam PF00149 Calcineurin-like phosphoesterase 3 189 7.8E-13 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 STK_05850 7c5f8b1e43964b85f8625784529b4567 220 SUPERFAMILY SSF56300 1 217 3.36E-21 T 23-10-2018 STK_18040 9260d4e6fbc0c7bab1c5e8a7812cfb6a 247 Pfam PF04909 Amidohydrolase 49 244 9.9E-44 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 STK_18040 9260d4e6fbc0c7bab1c5e8a7812cfb6a 247 SUPERFAMILY SSF51556 14 244 1.18E-48 T 23-10-2018 IPR032466 Metal-dependent hydrolase STK_18040 9260d4e6fbc0c7bab1c5e8a7812cfb6a 247 Gene3D G3DSA:3.20.20.140 3 246 2.8E-59 T 23-10-2018 STK_17990 bd6b94d74b8e6d7fa0f60599633b12d2 391 SUPERFAMILY SSF53901 10 233 5.55E-31 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_17990 bd6b94d74b8e6d7fa0f60599633b12d2 391 PIRSF PIRSF000429 5 390 6.4E-26 T 23-10-2018 IPR002155 Thiolase GO:0016747 STK_17990 bd6b94d74b8e6d7fa0f60599633b12d2 391 SUPERFAMILY SSF53901 235 388 5.52E-18 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_17990 bd6b94d74b8e6d7fa0f60599633b12d2 391 Gene3D G3DSA:3.40.47.10 6 391 2.4E-88 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_01090 d6d83954222b11bbd333be9bdf9adfdd 509 SUPERFAMILY SSF81648 239 385 2.49E-13 T 23-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 STK_01090 d6d83954222b11bbd333be9bdf9adfdd 509 SUPERFAMILY SSF81342 20 276 5.89E-47 T 23-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 STK_01090 d6d83954222b11bbd333be9bdf9adfdd 509 Gene3D G3DSA:1.20.810.10 20 419 8.8E-76 T 23-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 STK_01090 d6d83954222b11bbd333be9bdf9adfdd 509 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 94 273 1.0E-30 T 23-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 STK_18020 74b5e8a96d08efc89cffe78acfb27414 374 SUPERFAMILY SSF56645 4 224 4.45E-54 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 STK_18020 74b5e8a96d08efc89cffe78acfb27414 374 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 108 202 5.5E-20 T 23-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 STK_18020 74b5e8a96d08efc89cffe78acfb27414 374 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 214 363 1.7E-38 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 STK_18020 74b5e8a96d08efc89cffe78acfb27414 374 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 3 104 1.9E-16 T 23-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 STK_18020 74b5e8a96d08efc89cffe78acfb27414 374 Gene3D G3DSA:2.40.110.10 107 218 1.0E-29 T 23-10-2018 STK_18020 74b5e8a96d08efc89cffe78acfb27414 374 Gene3D G3DSA:1.10.540.10 2 106 1.5E-20 T 23-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 STK_18020 74b5e8a96d08efc89cffe78acfb27414 374 SUPERFAMILY SSF47203 212 367 4.35E-34 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 STK_18020 74b5e8a96d08efc89cffe78acfb27414 374 Gene3D G3DSA:1.20.140.10 219 371 3.1E-31 T 23-10-2018 STK_18020 74b5e8a96d08efc89cffe78acfb27414 374 PIRSF PIRSF016578 8 97 120.0 T 23-10-2018 STK_18020 74b5e8a96d08efc89cffe78acfb27414 374 PIRSF PIRSF016578 117 366 2.2E-13 T 23-10-2018 STK_07960 f361f4ab5c3965e7cdbc7917eb5bada0 526 PIRSF PIRSF006060 1 526 3.3E-75 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_07960 f361f4ab5c3965e7cdbc7917eb5bada0 526 Gene3D G3DSA:1.20.1740.10 24 381 2.8E-29 T 23-10-2018 STK_07960 f361f4ab5c3965e7cdbc7917eb5bada0 526 Pfam PF13520 Amino acid permease 35 490 1.5E-27 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_03440 24bab2fbb3a8f16f61dfa1af8aff7c6e 350 Gene3D G3DSA:3.40.50.1970 2 157 1.1E-33 T 23-10-2018 STK_03440 24bab2fbb3a8f16f61dfa1af8aff7c6e 350 Hamap MF_00497_A Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 7 349 45.693 T 23-10-2018 IPR023002 Glycerol-1-phosphate dehydrogenase, archaea GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 STK_03440 24bab2fbb3a8f16f61dfa1af8aff7c6e 350 SUPERFAMILY SSF56796 3 339 3.79E-74 T 23-10-2018 STK_03440 24bab2fbb3a8f16f61dfa1af8aff7c6e 350 PIRSF PIRSF000112 2 346 1.1E-64 T 23-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 STK_03440 24bab2fbb3a8f16f61dfa1af8aff7c6e 350 Gene3D G3DSA:1.20.1090.10 159 350 2.4E-61 T 23-10-2018 STK_03440 24bab2fbb3a8f16f61dfa1af8aff7c6e 350 Pfam PF13685 Iron-containing alcohol dehydrogenase 16 271 1.3E-65 T 23-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 STK_09060 52efc5c7d280783c3985c7e4f830c5c7 126 SUPERFAMILY SSF88723 6 121 1.79E-18 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_09060 52efc5c7d280783c3985c7e4f830c5c7 126 Gene3D G3DSA:3.40.50.1010 5 125 8.3E-14 T 23-10-2018 STK_09060 52efc5c7d280783c3985c7e4f830c5c7 126 Pfam PF01850 PIN domain 6 120 1.1E-13 T 23-10-2018 IPR002716 PIN domain STK_07510 cbd7f6250c30d5e615e071e8cc320803 107 Pfam PF01909 Nucleotidyltransferase domain 26 67 1.4E-7 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_07510 cbd7f6250c30d5e615e071e8cc320803 107 Gene3D G3DSA:3.30.460.10 20 107 8.0E-13 T 23-10-2018 STK_07510 cbd7f6250c30d5e615e071e8cc320803 107 SUPERFAMILY SSF81301 4 90 2.17E-15 T 23-10-2018 STK_07770 544076abd59a95b602f751498f7b99d6 157 Gene3D G3DSA:1.20.120.330 44 157 9.7E-7 T 23-10-2018 STK_07770 544076abd59a95b602f751498f7b99d6 157 Pfam PF05942 Archaeal PaREP1/PaREP8 family 49 149 7.2E-12 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_13724 098c62395b26350dcb40ecf7127c0169 88 SMART SM01380 2 79 5.9E-11 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_13724 098c62395b26350dcb40ecf7127c0169 88 Pfam PF01198 Ribosomal protein L31e 8 73 3.0E-8 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_13724 098c62395b26350dcb40ecf7127c0169 88 ProDom PD006030 RIBOSOMAL 60S L31 RIBONUCLEOPROTEIN L31E 50S L31 SUBUNIT STRAIN PHOSPHORYLATION 7 55 5.0E-5 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_13724 098c62395b26350dcb40ecf7127c0169 88 Hamap MF_00410 50S ribosomal protein L31e [rpl31e]. 2 84 15.336 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_13724 098c62395b26350dcb40ecf7127c0169 88 Gene3D G3DSA:3.10.440.10 1 86 1.2E-14 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_13724 098c62395b26350dcb40ecf7127c0169 88 SUPERFAMILY SSF54575 4 84 4.58E-22 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_00250 ebbb44cbd06c0803efd78f4ec4e6ac91 94 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 93 16.978 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 STK_00250 ebbb44cbd06c0803efd78f4ec4e6ac91 94 SUPERFAMILY SSF143430 1 83 7.32E-20 T 23-10-2018 STK_00250 ebbb44cbd06c0803efd78f4ec4e6ac91 94 Gene3D G3DSA:3.30.70.240 1 70 1.0E-26 T 23-10-2018 STK_00250 ebbb44cbd06c0803efd78f4ec4e6ac91 94 Pfam PF09827 CRISPR associated protein Cas2 1 77 7.3E-20 T 23-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 STK_00250 ebbb44cbd06c0803efd78f4ec4e6ac91 94 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 90 2.6E-17 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 STK_17750 b7abdcf5492a6f477e8a25623fdf8548 384 SUPERFAMILY SSF51905 1 306 3.02E-34 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_17750 b7abdcf5492a6f477e8a25623fdf8548 384 Pfam PF13450 NAD(P)-binding Rossmann-like domain 7 40 1.6E-8 T 23-10-2018 STK_17750 b7abdcf5492a6f477e8a25623fdf8548 384 Gene3D G3DSA:3.50.50.60 1 343 1.0E-53 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_17750 b7abdcf5492a6f477e8a25623fdf8548 384 SUPERFAMILY SSF54373 167 263 9.02E-5 T 23-10-2018 STK_17750 b7abdcf5492a6f477e8a25623fdf8548 384 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 273 288 7.7E-8 T 23-10-2018 STK_17750 b7abdcf5492a6f477e8a25623fdf8548 384 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 7.7E-8 T 23-10-2018 STK_22760 f4e2b64db122f6a32e90cfdd1db81bc3 260 PIRSF PIRSF005758 1 260 8.1E-90 T 23-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 STK_22760 f4e2b64db122f6a32e90cfdd1db81bc3 260 Pfam PF00288 GHMP kinases N terminal domain 61 127 3.8E-8 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 STK_22760 f4e2b64db122f6a32e90cfdd1db81bc3 260 SUPERFAMILY SSF55060 204 255 4.8E-6 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily STK_22760 f4e2b64db122f6a32e90cfdd1db81bc3 260 SUPERFAMILY SSF54211 6 138 6.75E-14 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold STK_22760 f4e2b64db122f6a32e90cfdd1db81bc3 260 TIGRFAM TIGR01920 Shik_kin_archae: shikimate kinase 3 251 7.9E-70 T 23-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 STK_22760 f4e2b64db122f6a32e90cfdd1db81bc3 260 Hamap MF_00370 Shikimate kinase [aroK]. 1 260 82.315 T 23-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 STK_22760 f4e2b64db122f6a32e90cfdd1db81bc3 260 Gene3D G3DSA:3.30.230.10 8 142 4.4E-14 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup STK_00970 d6fad4c9d7644345a1ad54283e7e3447 155 Gene3D G3DSA:3.30.530.20 1 155 3.7E-9 T 23-10-2018 IPR023393 START-like domain superfamily STK_00970 d6fad4c9d7644345a1ad54283e7e3447 155 Pfam PF11485 Protein of unknown function (DUF3211) 2 155 7.5E-42 T 23-10-2018 IPR021578 Protein of unknown function DUF3211 STK_04890 a749f4698c5384b0c242d34214da07bf 151 SMART SM00344 5 111 1.3E-47 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 STK_04890 a749f4698c5384b0c242d34214da07bf 151 Pfam PF13404 AsnC-type helix-turn-helix domain 5 46 2.0E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_04890 a749f4698c5384b0c242d34214da07bf 151 SUPERFAMILY SSF46785 3 65 2.2E-20 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_04890 a749f4698c5384b0c242d34214da07bf 151 SUPERFAMILY SSF54909 65 146 4.42E-20 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel STK_04890 a749f4698c5384b0c242d34214da07bf 151 Gene3D G3DSA:3.30.70.920 58 150 6.3E-26 T 23-10-2018 STK_04890 a749f4698c5384b0c242d34214da07bf 151 Pfam PF01037 Lrp/AsnC ligand binding domain 71 141 1.6E-17 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain STK_04890 a749f4698c5384b0c242d34214da07bf 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 4.9E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_04890 a749f4698c5384b0c242d34214da07bf 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 4.9E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_04890 a749f4698c5384b0c242d34214da07bf 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 4.9E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_04890 a749f4698c5384b0c242d34214da07bf 151 Gene3D G3DSA:1.10.10.10 3 55 3.0E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_20810 e8c9611309b6db9363f22510a8c92a7a 218 SUPERFAMILY SSF81301 10 64 1.4E-10 T 23-10-2018 STK_20810 e8c9611309b6db9363f22510a8c92a7a 218 PIRSF PIRSF005928 1 218 3.3E-100 T 23-10-2018 IPR009185 Predicted nucleotidyltransferase STK_20810 e8c9611309b6db9363f22510a8c92a7a 218 Pfam PF01909 Nucleotidyltransferase domain 19 105 1.2E-8 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_20810 e8c9611309b6db9363f22510a8c92a7a 218 Gene3D G3DSA:3.30.460.10 1 111 1.9E-8 T 23-10-2018 STK_13113 204b660c5c16e72a6d74bf0500bade1d 82 Gene3D G3DSA:1.10.10.10 4 66 3.5E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_13113 204b660c5c16e72a6d74bf0500bade1d 82 SUPERFAMILY SSF46785 4 60 5.9E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_11230 00a4e47e3a2786ea665778194d0eb12d 231 SUPERFAMILY SSF53335 1 206 1.52E-48 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_11230 00a4e47e3a2786ea665778194d0eb12d 231 Gene3D G3DSA:3.40.50.150 1 231 1.1E-68 T 23-10-2018 STK_11230 00a4e47e3a2786ea665778194d0eb12d 231 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 9 193 1.7E-38 T 23-10-2018 STK_03520 fbb65b4768780466cbe58a8f4dbc4d43 295 TIGRFAM TIGR01230 agmatinase: agmatinase 26 284 9.1E-70 T 23-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 STK_03520 fbb65b4768780466cbe58a8f4dbc4d43 295 ProSitePatterns PS01053 Arginase family signature. 217 238 - T 23-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 STK_03520 fbb65b4768780466cbe58a8f4dbc4d43 295 Pfam PF00491 Arginase family 26 284 1.6E-70 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 STK_03520 fbb65b4768780466cbe58a8f4dbc4d43 295 PIRSF PIRSF036979 1 293 2.4E-96 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 STK_03520 fbb65b4768780466cbe58a8f4dbc4d43 295 Gene3D G3DSA:3.40.800.10 9 294 1.4E-78 T 23-10-2018 STK_03520 fbb65b4768780466cbe58a8f4dbc4d43 295 SUPERFAMILY SSF52768 24 285 7.56E-79 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily STK_02340 e9160783c24d70efad8a2f62f6bdb9b0 607 Pfam PF04312 Protein of unknown function (DUF460) 218 358 1.9E-50 T 23-10-2018 IPR007408 Protein of unknown function DUF460 STK_01740 420b844ad88037563b7343a17065ebe2 298 Hamap MF_02040 Iron-sulfur cluster carrier protein. 37 289 35.455 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein STK_01740 420b844ad88037563b7343a17065ebe2 298 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 42 288 1.3E-95 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 STK_01740 420b844ad88037563b7343a17065ebe2 298 SUPERFAMILY SSF52540 44 292 9.92E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_01740 420b844ad88037563b7343a17065ebe2 298 Gene3D G3DSA:3.40.50.300 26 287 1.1E-82 T 23-10-2018 STK_19080 ede4394259939a62fe97d0209b0f9d19 316 Pfam PF01548 Transposase 6 134 3.9E-16 T 23-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 STK_19080 ede4394259939a62fe97d0209b0f9d19 316 Pfam PF02371 Transposase IS116/IS110/IS902 family 195 279 1.3E-26 T 23-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 STK_02970 497bba4d25933590d595921794fd56eb 324 TIGRFAM TIGR02236 recomb_radA: DNA repair and recombination protein RadA 14 321 7.2E-141 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 STK_02970 497bba4d25933590d595921794fd56eb 324 Hamap MF_00348 DNA repair and recombination protein RadA [radA]. 11 321 70.308 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 STK_02970 497bba4d25933590d595921794fd56eb 324 Pfam PF14520 Helix-hairpin-helix domain 12 67 1.3E-10 T 23-10-2018 STK_02970 497bba4d25933590d595921794fd56eb 324 SUPERFAMILY SSF47794 12 70 2.35E-11 T 23-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 STK_02970 497bba4d25933590d595921794fd56eb 324 PIRSF PIRSF005856 3 324 1.1E-126 T 23-10-2018 IPR016467 DNA recombination and repair protein, RecA-like Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 STK_02970 497bba4d25933590d595921794fd56eb 324 Pfam PF08423 Rad51 73 321 4.8E-90 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 STK_02970 497bba4d25933590d595921794fd56eb 324 Gene3D G3DSA:1.10.150.20 11 84 1.4E-22 T 23-10-2018 STK_02970 497bba4d25933590d595921794fd56eb 324 SUPERFAMILY SSF52540 86 321 1.28E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_02970 497bba4d25933590d595921794fd56eb 324 Gene3D G3DSA:3.40.50.300 85 324 4.3E-80 T 23-10-2018 STK_02970 497bba4d25933590d595921794fd56eb 324 SMART SM00382 106 291 2.2E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_01670 867ee009c6fa7c852e3ce7c764bbe1f0 207 SMART SM00863 159 202 7.5E-11 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 STK_01670 867ee009c6fa7c852e3ce7c764bbe1f0 207 Pfam PF01411 tRNA synthetases class II (A) 1 64 8.7E-11 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 STK_01670 867ee009c6fa7c852e3ce7c764bbe1f0 207 SUPERFAMILY SSF50447 1 59 3.53E-8 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily STK_01670 867ee009c6fa7c852e3ce7c764bbe1f0 207 SUPERFAMILY SSF55186 64 205 8.5E-35 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 STK_01670 867ee009c6fa7c852e3ce7c764bbe1f0 207 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 160 202 1.0E-10 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 STK_01670 867ee009c6fa7c852e3ce7c764bbe1f0 207 Gene3D G3DSA:2.40.30.130 1 60 6.4E-15 T 23-10-2018 STK_01670 867ee009c6fa7c852e3ce7c764bbe1f0 207 Gene3D G3DSA:3.30.980.10 61 207 7.0E-33 T 23-10-2018 STK_22280 e3adf569c0f0ae20292a89a1c3138f26 105 Gene3D G3DSA:3.30.2310.20 6 105 7.5E-7 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily STK_22280 e3adf569c0f0ae20292a89a1c3138f26 105 SUPERFAMILY SSF143011 33 101 2.22E-9 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily STK_22280 e3adf569c0f0ae20292a89a1c3138f26 105 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 17 103 3.3E-6 T 23-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family STK_20700 fd1ba16f6ebadd1b324ce6d0739cb8f9 172 SUPERFAMILY SSF46946 11 150 3.24E-34 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 STK_20700 fd1ba16f6ebadd1b324ce6d0739cb8f9 172 Gene3D G3DSA:1.10.8.50 1 78 4.4E-24 T 23-10-2018 STK_20700 fd1ba16f6ebadd1b324ce6d0739cb8f9 172 Gene3D G3DSA:4.10.910.10 91 140 3.6E-21 T 23-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_20700 fd1ba16f6ebadd1b324ce6d0739cb8f9 172 ProSitePatterns PS00646 Ribosomal protein S13 signature. 119 132 - T 23-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_20700 fd1ba16f6ebadd1b324ce6d0739cb8f9 172 Pfam PF00416 Ribosomal protein S13/S18 12 140 5.3E-49 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_20700 fd1ba16f6ebadd1b324ce6d0739cb8f9 172 PIRSF PIRSF002134 2 156 1.5E-43 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_20700 fd1ba16f6ebadd1b324ce6d0739cb8f9 172 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 10 150 24.842 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_20700 fd1ba16f6ebadd1b324ce6d0739cb8f9 172 TIGRFAM TIGR03629 uS13_arch: ribosomal protein uS13 6 150 5.2E-60 T 23-10-2018 IPR019977 Ribosomal protein S13, archaeal GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_25350 bfd8d9962c25074de94ae7ff8e48e00c 333 Gene3D G3DSA:1.10.3720.10 95 325 7.4E-11 T 23-10-2018 IPR035906 MetI-like superfamily STK_25350 bfd8d9962c25074de94ae7ff8e48e00c 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 330 1.1E-34 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 STK_25350 bfd8d9962c25074de94ae7ff8e48e00c 333 SUPERFAMILY SSF161098 102 313 4.09E-12 T 23-10-2018 IPR035906 MetI-like superfamily STK_04700 a9e8b53b39f9caee98253051cb9cf394 167 Pfam PF02926 THUMP domain 21 154 8.0E-12 T 23-10-2018 IPR004114 THUMP domain GO:0003723 STK_04700 a9e8b53b39f9caee98253051cb9cf394 167 SUPERFAMILY SSF143437 80 154 1.01E-9 T 23-10-2018 STK_04700 a9e8b53b39f9caee98253051cb9cf394 167 SMART SM00981 68 155 1.4E-9 T 23-10-2018 IPR004114 THUMP domain GO:0003723 STK_26360 d4c045bbfdab58d1bdf8302d8621fb8c 146 Pfam PF09702 CRISPR-associated protein (Cas_Csa5) 23 139 2.1E-53 T 23-10-2018 IPR010157 CRISPR type I-A/APERN-associated protein Csa5 STK_26360 d4c045bbfdab58d1bdf8302d8621fb8c 146 TIGRFAM TIGR01878 cas_Csa5: CRISPR type I-A/APERN-associated protein Csa5 22 139 3.8E-48 T 23-10-2018 IPR010157 CRISPR type I-A/APERN-associated protein Csa5 STK_22630 91a586d3e8f47ce99307789ef32d9b81 332 Gene3D G3DSA:3.40.50.11860 219 321 3.5E-29 T 23-10-2018 STK_22630 91a586d3e8f47ce99307789ef32d9b81 332 Gene3D G3DSA:3.40.50.11850 105 213 3.9E-26 T 23-10-2018 STK_22630 91a586d3e8f47ce99307789ef32d9b81 332 Gene3D G3DSA:3.40.50.11840 6 102 1.0E-27 T 23-10-2018 STK_22630 91a586d3e8f47ce99307789ef32d9b81 332 TIGRFAM TIGR03682 arCOG04112: diphthamide biosynthesis enzyme Dph2 18 330 6.4E-93 T 23-10-2018 IPR022428 Diphthamide synthesis Dph2, archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546 STK_22630 91a586d3e8f47ce99307789ef32d9b81 332 PIRSF PIRSF004967 1 332 3.6E-86 T 23-10-2018 IPR035435 Diphthamide synthesis DHP1/DPH2, eukaryotes and archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 STK_22630 91a586d3e8f47ce99307789ef32d9b81 332 Pfam PF01866 Putative diphthamide synthesis protein 26 322 1.4E-76 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 STK_22630 91a586d3e8f47ce99307789ef32d9b81 332 TIGRFAM TIGR00322 diphth2_R: diphthamide biosynthesis enzyme Dph1/Dph2 domain 3 320 9.9E-94 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 STK_04190 a17afd934f11c2dcc906a7ae57a38357 133 ProSitePatterns PS00053 Ribosomal protein S8 signature. 103 120 - T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04190 a17afd934f11c2dcc906a7ae57a38357 133 Hamap MF_01302_A 30S ribosomal protein S8 [rpsH]. 2 133 35.216 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04190 a17afd934f11c2dcc906a7ae57a38357 133 Gene3D G3DSA:3.30.1490.10 70 131 2.0E-22 T 23-10-2018 STK_04190 a17afd934f11c2dcc906a7ae57a38357 133 SUPERFAMILY SSF56047 4 133 3.01E-37 T 23-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04190 a17afd934f11c2dcc906a7ae57a38357 133 Gene3D G3DSA:3.30.1370.30 1 69 5.0E-32 T 23-10-2018 STK_04190 a17afd934f11c2dcc906a7ae57a38357 133 Pfam PF00410 Ribosomal protein S8 5 133 2.3E-24 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_13446 10cdd62eddf208995afe63b63351c403 71 SUPERFAMILY SSF47598 1 39 5.19E-6 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 STK_13446 10cdd62eddf208995afe63b63351c403 71 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 39 1.4E-8 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 STK_20440 7ed9096aa96d86dcf6c430d16ae1bbd6 162 Gene3D G3DSA:3.40.50.300 1 140 4.5E-31 T 23-10-2018 STK_20440 7ed9096aa96d86dcf6c430d16ae1bbd6 162 SUPERFAMILY SSF52540 4 104 1.29E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_20440 7ed9096aa96d86dcf6c430d16ae1bbd6 162 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 4 137 5.0E-43 T 23-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 STK_20440 7ed9096aa96d86dcf6c430d16ae1bbd6 162 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 108 1.2E-24 T 23-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 STK_07150 90f3d1674ba9ce9235f9dd0eb7809267 257 Pfam PF04693 Archaeal putative transposase ISC1217 185 230 1.4E-15 T 23-10-2018 IPR006783 Transposase, ISC1217 STK_07150 90f3d1674ba9ce9235f9dd0eb7809267 257 Pfam PF04693 Archaeal putative transposase ISC1217 1 87 1.1E-34 T 23-10-2018 IPR006783 Transposase, ISC1217 STK_08310 bfd2ecbed85def8259169117d4a81531 412 Pfam PF04167 Protein of unknown function (DUF402) 326 386 2.3E-14 T 23-10-2018 IPR007295 Domain of unknown function DUF402 STK_08310 bfd2ecbed85def8259169117d4a81531 412 Hamap MF_01910 RNA-binding protein AU-1 [aubA]. 1 412 29.465 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 STK_08310 bfd2ecbed85def8259169117d4a81531 412 SUPERFAMILY SSF159234 264 410 8.11E-21 T 23-10-2018 IPR035930 FomD-like superfamily STK_08310 bfd2ecbed85def8259169117d4a81531 412 PIRSF PIRSF018644 1 412 9.5E-154 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 STK_01720 d9c1052e1d90db6f81b31160687f64de 239 Gene3D G3DSA:3.40.50.10420 33 202 6.2E-12 T 23-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily STK_01720 d9c1052e1d90db6f81b31160687f64de 239 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 4 195 1.1E-32 T 23-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase STK_01720 d9c1052e1d90db6f81b31160687f64de 239 SUPERFAMILY SSF100950 3 213 7.39E-35 T 23-10-2018 IPR037171 NagB/RpiA transferase-like STK_04110 b0ed426590de83f9b014268a8e01db21 463 PIRSF PIRSF004557 4 463 6.1E-95 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 STK_04110 b0ed426590de83f9b014268a8e01db21 463 ProSitePatterns PS00756 Protein secY signature 2. 161 179 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 STK_04110 b0ed426590de83f9b014268a8e01db21 463 ProSitePatterns PS00755 Protein secY signature 1. 74 93 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 STK_04110 b0ed426590de83f9b014268a8e01db21 463 Gene3D G3DSA:1.10.3370.10 5 463 5.7E-121 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 STK_04110 b0ed426590de83f9b014268a8e01db21 463 SUPERFAMILY SSF103491 5 448 1.18E-92 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 STK_04110 b0ed426590de83f9b014268a8e01db21 463 Pfam PF00344 SecY translocase 74 442 8.1E-57 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 STK_04110 b0ed426590de83f9b014268a8e01db21 463 Pfam PF10559 Plug domain of Sec61p 38 73 8.2E-8 T 23-10-2018 IPR019561 Translocon Sec61/SecY, plug domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 STK_04290 916f6d253c1baac3e7618c111206d50f 343 Pfam PF00297 Ribosomal protein L3 1 342 1.4E-76 T 23-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_04290 916f6d253c1baac3e7618c111206d50f 343 Hamap MF_01325_A 50S ribosomal protein L3 [rplC]. 1 342 48.721 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_04290 916f6d253c1baac3e7618c111206d50f 343 Gene3D G3DSA:4.10.960.10 9 263 3.3E-113 T 23-10-2018 STK_04290 916f6d253c1baac3e7618c111206d50f 343 Gene3D G3DSA:2.40.30.10 43 323 3.3E-113 T 23-10-2018 STK_04290 916f6d253c1baac3e7618c111206d50f 343 TIGRFAM TIGR03626 L3_arch: ribosomal protein uL3 8 340 4.9E-133 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_04290 916f6d253c1baac3e7618c111206d50f 343 Gene3D G3DSA:3.30.1430.10 82 196 3.3E-113 T 23-10-2018 STK_04290 916f6d253c1baac3e7618c111206d50f 343 ProSitePatterns PS00474 Ribosomal protein L3 signature. 201 224 - T 23-10-2018 IPR019926 Ribosomal protein L3, conserved site STK_04290 916f6d253c1baac3e7618c111206d50f 343 SUPERFAMILY SSF50447 4 343 2.91E-91 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily STK_02710 00fcfde6a6ccc16dcbb86d56a4472a95 159 Gene3D G3DSA:3.10.690.10 72 158 1.7E-5 T 23-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 STK_02710 00fcfde6a6ccc16dcbb86d56a4472a95 159 Pfam PF02577 Bifunctional nuclease 82 150 1.3E-6 T 23-10-2018 IPR003729 Bifunctional nuclease domain GO:0004518 STK_02710 00fcfde6a6ccc16dcbb86d56a4472a95 159 SUPERFAMILY SSF103256 9 158 6.02E-28 T 23-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 STK_26130 b438330ff26e23848788819d60a130f4 177 Pfam PF05942 Archaeal PaREP1/PaREP8 family 19 143 1.1E-20 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_24840 967640d07113dc3909c5f9d172d59de3 730 SMART SM01008 17 118 1.5E-38 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead STK_24840 967640d07113dc3909c5f9d172d59de3 730 Gene3D G3DSA:3.30.365.10 349 713 1.4E-114 T 23-10-2018 STK_24840 967640d07113dc3909c5f9d172d59de3 730 SUPERFAMILY SSF56003 111 728 8.9E-181 T 23-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 STK_24840 967640d07113dc3909c5f9d172d59de3 730 Gene3D G3DSA:3.30.365.10 432 589 1.4E-114 T 23-10-2018 STK_24840 967640d07113dc3909c5f9d172d59de3 730 Gene3D G3DSA:3.30.365.10 138 340 5.9E-62 T 23-10-2018 STK_24840 967640d07113dc3909c5f9d172d59de3 730 Gene3D G3DSA:3.90.1170.50 1 118 1.5E-34 T 23-10-2018 STK_24840 967640d07113dc3909c5f9d172d59de3 730 Gene3D G3DSA:3.30.365.10 172 266 5.9E-62 T 23-10-2018 STK_24840 967640d07113dc3909c5f9d172d59de3 730 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 138 671 3.5E-160 T 23-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 STK_24840 967640d07113dc3909c5f9d172d59de3 730 SUPERFAMILY SSF54665 2 134 9.29E-38 T 23-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily STK_24840 967640d07113dc3909c5f9d172d59de3 730 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 17 118 5.1E-26 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead STK_23610 ebb5c58f51fd0dd7a41e849219f1a5ab 390 Gene3D G3DSA:1.20.1250.20 200 385 6.9E-21 T 23-10-2018 STK_23610 ebb5c58f51fd0dd7a41e849219f1a5ab 390 Gene3D G3DSA:1.20.1250.20 5 196 5.2E-16 T 23-10-2018 STK_23610 ebb5c58f51fd0dd7a41e849219f1a5ab 390 Pfam PF07690 Major Facilitator Superfamily 10 292 7.9E-25 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_23610 ebb5c58f51fd0dd7a41e849219f1a5ab 390 ProSitePatterns PS00216 Sugar transport proteins signature 1. 261 278 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 STK_23610 ebb5c58f51fd0dd7a41e849219f1a5ab 390 SUPERFAMILY SSF103473 3 383 5.1E-45 T 23-10-2018 IPR036259 MFS transporter superfamily STK_03390 8dd5aece9cc0ca7bdf8aa530b9e66448 365 Gene3D G3DSA:1.20.1250.20 2 365 1.3E-36 T 23-10-2018 STK_03390 8dd5aece9cc0ca7bdf8aa530b9e66448 365 SUPERFAMILY SSF103473 2 362 5.36E-38 T 23-10-2018 IPR036259 MFS transporter superfamily STK_03390 8dd5aece9cc0ca7bdf8aa530b9e66448 365 Pfam PF07690 Major Facilitator Superfamily 6 220 7.5E-16 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_03390 8dd5aece9cc0ca7bdf8aa530b9e66448 365 Pfam PF07690 Major Facilitator Superfamily 237 359 2.8E-11 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_10550 7f149486073aa06227d51863a274e9bc 173 SUPERFAMILY SSF53041 34 156 2.35E-19 T 23-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 STK_10550 7f149486073aa06227d51863a274e9bc 173 Pfam PF00239 Resolvase, N terminal domain 35 166 1.3E-16 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 STK_10550 7f149486073aa06227d51863a274e9bc 173 ProSitePatterns PS00397 Site-specific recombinases active site. 38 46 - T 23-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 STK_10550 7f149486073aa06227d51863a274e9bc 173 SMART SM00857 35 169 1.2E-14 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 STK_10550 7f149486073aa06227d51863a274e9bc 173 Gene3D G3DSA:3.40.50.1390 31 129 5.6E-26 T 23-10-2018 STK_02400 b65bfdd466c48a2b17a6829421bea376 140 Pfam PF09921 Uncharacterized protein conserved in archaea (DUF2153) 8 131 4.1E-55 T 23-10-2018 IPR014450 Uncharacterised conserved protein UCP008210 STK_02400 b65bfdd466c48a2b17a6829421bea376 140 PIRSF PIRSF008210 1 140 1.6E-70 T 23-10-2018 IPR014450 Uncharacterised conserved protein UCP008210 STK_14870 34c7444167acf614e910f0f973aa40a0 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 51 7.1E-56 T 23-10-2018 STK_14870 34c7444167acf614e910f0f973aa40a0 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 417 437 7.1E-56 T 23-10-2018 STK_14870 34c7444167acf614e910f0f973aa40a0 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 395 410 7.1E-56 T 23-10-2018 STK_14870 34c7444167acf614e910f0f973aa40a0 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 331 352 7.1E-56 T 23-10-2018 STK_14870 34c7444167acf614e910f0f973aa40a0 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 7.1E-56 T 23-10-2018 STK_14870 34c7444167acf614e910f0f973aa40a0 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 129 138 7.1E-56 T 23-10-2018 STK_14870 34c7444167acf614e910f0f973aa40a0 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 165 190 7.1E-56 T 23-10-2018 STK_14870 34c7444167acf614e910f0f973aa40a0 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 7.1E-56 T 23-10-2018 STK_14870 34c7444167acf614e910f0f973aa40a0 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 254 268 7.1E-56 T 23-10-2018 STK_14870 34c7444167acf614e910f0f973aa40a0 452 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 335 441 9.5E-26 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 STK_14870 34c7444167acf614e910f0f973aa40a0 452 SUPERFAMILY SSF55424 334 446 6.36E-32 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 STK_14870 34c7444167acf614e910f0f973aa40a0 452 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 317 6.0E-63 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 STK_14870 34c7444167acf614e910f0f973aa40a0 452 Gene3D G3DSA:3.50.50.60 3 323 3.1E-92 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_14870 34c7444167acf614e910f0f973aa40a0 452 Gene3D G3DSA:3.30.390.30 333 451 2.6E-30 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 STK_14870 34c7444167acf614e910f0f973aa40a0 452 Gene3D G3DSA:3.50.50.60 138 260 3.1E-92 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_14870 34c7444167acf614e910f0f973aa40a0 452 PIRSF PIRSF000350 1 445 9.3E-79 T 23-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 STK_14870 34c7444167acf614e910f0f973aa40a0 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 126 144 4.8E-33 T 23-10-2018 STK_14870 34c7444167acf614e910f0f973aa40a0 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 269 4.8E-33 T 23-10-2018 STK_14870 34c7444167acf614e910f0f973aa40a0 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 4.8E-33 T 23-10-2018 STK_14870 34c7444167acf614e910f0f973aa40a0 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 165 183 4.8E-33 T 23-10-2018 STK_14870 34c7444167acf614e910f0f973aa40a0 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 4.8E-33 T 23-10-2018 STK_14870 34c7444167acf614e910f0f973aa40a0 452 SUPERFAMILY SSF51905 1 326 9.72E-51 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_25070 969bdca2d1e852f747d328ba84a81a05 227 Pfam PF02633 Creatinine amidohydrolase 15 222 6.0E-43 T 23-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 STK_25070 969bdca2d1e852f747d328ba84a81a05 227 Gene3D G3DSA:3.40.50.10310 9 226 1.7E-41 T 23-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 STK_25070 969bdca2d1e852f747d328ba84a81a05 227 SUPERFAMILY SSF102215 2 225 7.45E-52 T 23-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 STK_25570 de47b6db49c7c31edf0a78d5dd241396 459 SUPERFAMILY SSF103473 7 440 7.72E-66 T 23-10-2018 IPR036259 MFS transporter superfamily STK_25570 de47b6db49c7c31edf0a78d5dd241396 459 ProSitePatterns PS00216 Sugar transport proteins signature 1. 299 315 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 STK_25570 de47b6db49c7c31edf0a78d5dd241396 459 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 15 440 1.3E-80 T 23-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 STK_25570 de47b6db49c7c31edf0a78d5dd241396 459 PRINTS PR00171 Sugar transporter signature 369 381 9.8E-19 T 23-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 STK_25570 de47b6db49c7c31edf0a78d5dd241396 459 PRINTS PR00171 Sugar transporter signature 255 265 9.8E-19 T 23-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 STK_25570 de47b6db49c7c31edf0a78d5dd241396 459 PRINTS PR00171 Sugar transporter signature 346 367 9.8E-19 T 23-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 STK_25570 de47b6db49c7c31edf0a78d5dd241396 459 PRINTS PR00171 Sugar transporter signature 25 35 9.8E-19 T 23-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 STK_25570 de47b6db49c7c31edf0a78d5dd241396 459 PRINTS PR00171 Sugar transporter signature 108 127 9.8E-19 T 23-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 STK_25570 de47b6db49c7c31edf0a78d5dd241396 459 Pfam PF00083 Sugar (and other) transporter 18 445 4.7E-88 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 STK_25570 de47b6db49c7c31edf0a78d5dd241396 459 ProSitePatterns PS00217 Sugar transport proteins signature 2. 113 138 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 STK_25570 de47b6db49c7c31edf0a78d5dd241396 459 Gene3D G3DSA:1.20.1250.20 8 448 8.6E-103 T 23-10-2018 STK_26120 bf5bca7f877469e2d7a6e4f215fa5037 242 Pfam PF08445 FR47-like protein 146 233 3.9E-29 T 23-10-2018 IPR013653 FR47-like GO:0016747 STK_26120 bf5bca7f877469e2d7a6e4f215fa5037 242 Gene3D G3DSA:3.40.630.30 25 230 4.9E-24 T 23-10-2018 STK_26120 bf5bca7f877469e2d7a6e4f215fa5037 242 SUPERFAMILY SSF55729 5 233 1.49E-30 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase STK_22780 a6c3837b3a7c12cb2e7e37b8539c294f 216 SUPERFAMILY SSF51569 2 203 2.09E-29 T 23-10-2018 STK_22780 a6c3837b3a7c12cb2e7e37b8539c294f 216 Gene3D G3DSA:3.20.20.70 9 204 8.5E-21 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_22780 a6c3837b3a7c12cb2e7e37b8539c294f 216 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 3 203 32.462 T 23-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 STK_22780 a6c3837b3a7c12cb2e7e37b8539c294f 216 Pfam PF01487 Type I 3-dehydroquinase 21 200 4.0E-8 T 23-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 STK_05920 1b13964f2ce2e6585bccfeb27c2e8c91 167 SUPERFAMILY SSF51230 92 166 2.22E-22 T 23-10-2018 IPR011053 Single hybrid motif STK_05920 1b13964f2ce2e6585bccfeb27c2e8c91 167 Pfam PF00364 Biotin-requiring enzyme 100 166 7.1E-19 T 23-10-2018 IPR000089 Biotin/lipoyl attachment STK_05920 1b13964f2ce2e6585bccfeb27c2e8c91 167 Gene3D G3DSA:2.40.50.100 94 167 1.8E-25 T 23-10-2018 STK_19890 c0a700d698eac361da3c4c8e1f81261b 139 Gene3D G3DSA:1.20.120.330 20 137 2.1E-8 T 23-10-2018 STK_19890 c0a700d698eac361da3c4c8e1f81261b 139 Pfam PF05942 Archaeal PaREP1/PaREP8 family 36 124 1.8E-6 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_11870 f37db7362260492f68f1cc251ed8aa6a 199 Gene3D G3DSA:1.20.120.1630 8 199 7.6E-38 T 23-10-2018 STK_11870 f37db7362260492f68f1cc251ed8aa6a 199 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 88 176 2.1E-13 T 23-10-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 STK_10520 5fbf0bc59bfda2b83da39186b26685ed 364 Gene3D G3DSA:1.20.1250.20 191 363 7.3E-7 T 23-10-2018 STK_10520 5fbf0bc59bfda2b83da39186b26685ed 364 Pfam PF07690 Major Facilitator Superfamily 14 326 1.2E-21 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_10520 5fbf0bc59bfda2b83da39186b26685ed 364 Gene3D G3DSA:1.20.1250.20 2 190 2.4E-27 T 23-10-2018 STK_10520 5fbf0bc59bfda2b83da39186b26685ed 364 SUPERFAMILY SSF103473 9 356 3.66E-39 T 23-10-2018 IPR036259 MFS transporter superfamily STK_08370 9654b567c2a8cc6a58d718bf8a49a36d 123 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 22 82 5.0E-13 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal STK_08370 9654b567c2a8cc6a58d718bf8a49a36d 123 Gene3D G3DSA:1.10.10.10 12 117 1.6E-30 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_08370 9654b567c2a8cc6a58d718bf8a49a36d 123 SUPERFAMILY SSF46785 19 118 3.19E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_00375 da926af635360bf43e3161aff19191fc 108 Pfam PF01909 Nucleotidyltransferase domain 21 93 2.0E-6 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_00375 da926af635360bf43e3161aff19191fc 108 Gene3D G3DSA:3.30.460.10 2 108 4.6E-25 T 23-10-2018 STK_00375 da926af635360bf43e3161aff19191fc 108 SUPERFAMILY SSF81301 21 103 1.25E-13 T 23-10-2018 STK_12580 43f79006cf7ec18ae12ccbcf1dbdc0ef 623 Pfam PF00750 tRNA synthetases class I (R) 102 464 7.4E-34 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 STK_12580 43f79006cf7ec18ae12ccbcf1dbdc0ef 623 SMART SM00836 507 623 1.6E-23 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 STK_12580 43f79006cf7ec18ae12ccbcf1dbdc0ef 623 PRINTS PR01038 Arginyl-tRNA synthetase signature 123 139 1.5E-13 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 STK_12580 43f79006cf7ec18ae12ccbcf1dbdc0ef 623 PRINTS PR01038 Arginyl-tRNA synthetase signature 108 123 1.5E-13 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 STK_12580 43f79006cf7ec18ae12ccbcf1dbdc0ef 623 PRINTS PR01038 Arginyl-tRNA synthetase signature 147 160 1.5E-13 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 STK_12580 43f79006cf7ec18ae12ccbcf1dbdc0ef 623 Gene3D G3DSA:1.10.730.10 507 623 1.8E-24 T 23-10-2018 STK_12580 43f79006cf7ec18ae12ccbcf1dbdc0ef 623 Pfam PF05746 DALR anticodon binding domain 507 623 2.4E-26 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 STK_12580 43f79006cf7ec18ae12ccbcf1dbdc0ef 623 SUPERFAMILY SSF55190 2 99 4.58E-10 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 STK_12580 43f79006cf7ec18ae12ccbcf1dbdc0ef 623 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 623 22.18 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 STK_12580 43f79006cf7ec18ae12ccbcf1dbdc0ef 623 SUPERFAMILY SSF47323 502 623 1.44E-25 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_12580 43f79006cf7ec18ae12ccbcf1dbdc0ef 623 SUPERFAMILY SSF52374 103 499 1.72E-71 T 23-10-2018 STK_12580 43f79006cf7ec18ae12ccbcf1dbdc0ef 623 Gene3D G3DSA:3.30.1360.70 1 99 8.2E-11 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 STK_12580 43f79006cf7ec18ae12ccbcf1dbdc0ef 623 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 5 623 1.4E-109 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 STK_10240 df19a29c36556b4e30fc22a721177fad 199 Pfam PF01774 UreD urease accessory protein 29 151 7.2E-11 T 23-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 STK_01050 1ad0c4c6f0b880db59b977481820e807 147 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 68 135 1.3E-11 T 23-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01050 1ad0c4c6f0b880db59b977481820e807 147 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 87 135 - T 23-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_01050 1ad0c4c6f0b880db59b977481820e807 147 Gene3D G3DSA:2.60.40.420 31 147 1.3E-33 T 23-10-2018 IPR008972 Cupredoxin STK_01050 1ad0c4c6f0b880db59b977481820e807 147 SUPERFAMILY SSF49503 39 144 1.58E-33 T 23-10-2018 IPR008972 Cupredoxin STK_14260 c67c1cd7038c67cb01b6e3b0a79fd824 876 Gene3D G3DSA:1.10.287.690 558 618 2.3E-67 T 23-10-2018 STK_14260 c67c1cd7038c67cb01b6e3b0a79fd824 876 SUPERFAMILY SSF56672 450 861 8.9E-113 T 23-10-2018 STK_14260 c67c1cd7038c67cb01b6e3b0a79fd824 876 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 597 609 1.7E-10 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 STK_14260 c67c1cd7038c67cb01b6e3b0a79fd824 876 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 508 521 1.7E-10 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 STK_14260 c67c1cd7038c67cb01b6e3b0a79fd824 876 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 649 657 1.7E-10 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 STK_14260 c67c1cd7038c67cb01b6e3b0a79fd824 876 SUPERFAMILY SSF53098 41 445 1.84E-83 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily STK_14260 c67c1cd7038c67cb01b6e3b0a79fd824 876 SMART SM00486 223 663 1.0E-105 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 STK_14260 c67c1cd7038c67cb01b6e3b0a79fd824 876 Gene3D G3DSA:3.90.1600.10 497 693 2.3E-67 T 23-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 STK_14260 c67c1cd7038c67cb01b6e3b0a79fd824 876 Gene3D G3DSA:3.30.342.10 52 474 9.4E-181 T 23-10-2018 STK_14260 c67c1cd7038c67cb01b6e3b0a79fd824 876 Pfam PF03104 DNA polymerase family B, exonuclease domain 77 360 7.9E-31 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 STK_14260 c67c1cd7038c67cb01b6e3b0a79fd824 876 Gene3D G3DSA:3.30.420.10 226 419 9.4E-181 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 STK_14260 c67c1cd7038c67cb01b6e3b0a79fd824 876 Pfam PF00136 DNA polymerase family B 453 830 6.9E-51 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 STK_14260 c67c1cd7038c67cb01b6e3b0a79fd824 876 Gene3D G3DSA:1.10.132.60 713 874 2.2E-13 T 23-10-2018 STK_14260 c67c1cd7038c67cb01b6e3b0a79fd824 876 ProSitePatterns PS00116 DNA polymerase family B signature. 651 659 - T 23-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 STK_25810 c76b2b1e1e55a599a4b8823121288c79 346 Gene3D G3DSA:1.20.1250.20 7 339 3.7E-12 T 23-10-2018 STK_25810 c76b2b1e1e55a599a4b8823121288c79 346 SUPERFAMILY SSF103473 11 338 8.24E-15 T 23-10-2018 IPR036259 MFS transporter superfamily STK_09030 9fea4dcd8588c986981740b758e13220 869 SUPERFAMILY SSF49309 494 562 1.47E-9 T 23-10-2018 IPR036238 Transglutaminase, C-terminal domain superfamily GO:0003810|GO:0018149 STK_26260 fae9656cc18d2650fa890878d5620c76 738 SUPERFAMILY SSF49299 514 624 8.44E-6 T 23-10-2018 IPR035986 PKD domain superfamily STK_26260 fae9656cc18d2650fa890878d5620c76 738 Pfam PF05317 Thermopsin 97 353 1.3E-80 T 23-10-2018 IPR007981 Peptidase A5, thermopsin STK_22700 61287136776e70c051dee7689f17e4b5 341 SUPERFAMILY SSF51735 95 273 2.08E-19 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_22700 61287136776e70c051dee7689f17e4b5 341 SUPERFAMILY SSF48600 4 88 3.66E-21 T 23-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 STK_22700 61287136776e70c051dee7689f17e4b5 341 SUPERFAMILY SSF48179 248 337 2.04E-5 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 STK_22700 61287136776e70c051dee7689f17e4b5 341 Pfam PF02153 Prephenate dehydrogenase 115 338 9.1E-18 T 23-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 STK_22700 61287136776e70c051dee7689f17e4b5 341 Gene3D G3DSA:1.20.59.10 1 94 2.5E-18 T 23-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 STK_22700 61287136776e70c051dee7689f17e4b5 341 TIGRFAM TIGR01791 CM_archaeal: chorismate mutase 5 86 7.2E-35 T 23-10-2018 IPR010950 Chorismate mutase, archaeal KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 STK_22700 61287136776e70c051dee7689f17e4b5 341 PIRSF PIRSF001499 1 341 1.4E-128 T 23-10-2018 IPR008244 Bifunctional chorismate mutase/prephenate dehydrogenase T-protein GO:0004106|GO:0005737|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+5.4.99.5+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7303|MetaCyc: PWY-7626 STK_22700 61287136776e70c051dee7689f17e4b5 341 SMART SM00830 9 89 2.9E-22 T 23-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 STK_22700 61287136776e70c051dee7689f17e4b5 341 Pfam PF01817 Chorismate mutase type II 9 86 1.7E-14 T 23-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 STK_22700 61287136776e70c051dee7689f17e4b5 341 Gene3D G3DSA:3.40.50.720 95 254 1.2E-21 T 23-10-2018 STK_22030 871813087aeaebcc2a12ce294d623c9e 522 Gene3D G3DSA:3.20.20.70 5 328 2.4E-108 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_22030 871813087aeaebcc2a12ce294d623c9e 522 SUPERFAMILY SSF110921 407 509 7.32E-14 T 23-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 STK_22030 871813087aeaebcc2a12ce294d623c9e 522 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 13 29 - T 23-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 STK_22030 871813087aeaebcc2a12ce294d623c9e 522 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 5 514 1.0E-187 T 23-10-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 STK_22030 871813087aeaebcc2a12ce294d623c9e 522 Pfam PF08502 LeuA allosteric (dimerisation) domain 382 510 1.8E-24 T 23-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 STK_22030 871813087aeaebcc2a12ce294d623c9e 522 Pfam PF00682 HMGL-like 6 278 2.7E-52 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 STK_22030 871813087aeaebcc2a12ce294d623c9e 522 SMART SM00917 377 511 7.0E-29 T 23-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 STK_22030 871813087aeaebcc2a12ce294d623c9e 522 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 204 217 - T 23-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 STK_22030 871813087aeaebcc2a12ce294d623c9e 522 SUPERFAMILY SSF51569 2 295 3.66E-82 T 23-10-2018 STK_14690 e92cbf70da8e9cf2e4df966118e938c8 453 Gene3D G3DSA:3.30.930.10 106 445 6.8E-118 T 23-10-2018 STK_14690 e92cbf70da8e9cf2e4df966118e938c8 453 SUPERFAMILY SSF55681 157 437 3.32E-80 T 23-10-2018 STK_14690 e92cbf70da8e9cf2e4df966118e938c8 453 TIGRFAM TIGR00414 serS: serine--tRNA ligase 7 437 3.7E-145 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 STK_14690 e92cbf70da8e9cf2e4df966118e938c8 453 Gene3D G3DSA:1.10.287.40 6 105 1.7E-24 T 23-10-2018 STK_14690 e92cbf70da8e9cf2e4df966118e938c8 453 SUPERFAMILY SSF46589 7 113 2.98E-24 T 23-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 STK_14690 e92cbf70da8e9cf2e4df966118e938c8 453 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 242 420 2.5E-40 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_14690 e92cbf70da8e9cf2e4df966118e938c8 453 Hamap MF_00176 Serine--tRNA ligase [serS]. 3 442 37.942 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 STK_14690 e92cbf70da8e9cf2e4df966118e938c8 453 PRINTS PR00981 Seryl-tRNA synthetase signature 285 297 1.5E-29 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 STK_14690 e92cbf70da8e9cf2e4df966118e938c8 453 PRINTS PR00981 Seryl-tRNA synthetase signature 297 310 1.5E-29 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 STK_14690 e92cbf70da8e9cf2e4df966118e938c8 453 PRINTS PR00981 Seryl-tRNA synthetase signature 337 350 1.5E-29 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 STK_14690 e92cbf70da8e9cf2e4df966118e938c8 453 PRINTS PR00981 Seryl-tRNA synthetase signature 354 370 1.5E-29 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 STK_14690 e92cbf70da8e9cf2e4df966118e938c8 453 PRINTS PR00981 Seryl-tRNA synthetase signature 372 388 1.5E-29 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 STK_14690 e92cbf70da8e9cf2e4df966118e938c8 453 PIRSF PIRSF001529 5 445 2.0E-139 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 STK_14690 e92cbf70da8e9cf2e4df966118e938c8 453 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 7 108 2.0E-23 T 23-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 STK_05750 9bc4f4d317aa65cca15ea57433315bd3 452 Gene3D G3DSA:2.40.50.360 119 250 4.2E-108 T 23-10-2018 STK_05750 9bc4f4d317aa65cca15ea57433315bd3 452 Pfam PF06068 TIP49 C-terminus 14 411 9.3E-159 T 23-10-2018 IPR010339 TIP49, C-terminal GO:0003678|GO:0005524 Reactome: R-HSA-171319|Reactome: R-HSA-3214847 STK_05750 9bc4f4d317aa65cca15ea57433315bd3 452 Gene3D G3DSA:3.40.50.300 18 357 4.2E-108 T 23-10-2018 STK_05750 9bc4f4d317aa65cca15ea57433315bd3 452 SUPERFAMILY SSF52540 35 432 2.22E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_05750 9bc4f4d317aa65cca15ea57433315bd3 452 SMART SM00382 62 374 2.8E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_05750 9bc4f4d317aa65cca15ea57433315bd3 452 Gene3D G3DSA:1.10.8.60 362 452 1.5E-27 T 23-10-2018 STK_13230 a82fdbd63d080170217c9744bd740984 526 Pfam PF13173 AAA domain 59 179 2.5E-25 T 23-10-2018 STK_13230 a82fdbd63d080170217c9744bd740984 526 SMART SM00382 57 207 1.9E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_13230 a82fdbd63d080170217c9744bd740984 526 Pfam PF13635 Domain of unknown function (DUF4143) 373 474 4.8E-8 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 STK_13230 a82fdbd63d080170217c9744bd740984 526 SUPERFAMILY SSF52540 53 177 1.31E-13 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_22580 58d909fbdade84b230c981c931a5603b 237 Gene3D G3DSA:3.30.1360.160 121 218 2.3E-9 T 23-10-2018 STK_22580 58d909fbdade84b230c981c931a5603b 237 Gene3D G3DSA:1.20.120.1220 14 234 2.3E-9 T 23-10-2018 STK_22580 58d909fbdade84b230c981c931a5603b 237 Pfam PF01478 Type IV leader peptidase family 12 110 4.1E-7 T 23-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 STK_22580 58d909fbdade84b230c981c931a5603b 237 Pfam PF06847 Archaeal Peptidase A24 C-terminus Type II 143 234 4.8E-25 T 23-10-2018 IPR009655 Preflagellin peptidase, C-terminal STK_24125 0f0733c0542c5aa530dde732b08a6164 53 SUPERFAMILY SSF48179 7 48 5.1E-7 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 STK_24125 0f0733c0542c5aa530dde732b08a6164 53 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 8 49 5.4E-5 T 23-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 STK_24125 0f0733c0542c5aa530dde732b08a6164 53 Gene3D G3DSA:1.10.1040.10 3 53 5.4E-10 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 STK_21070 de0ba7a65817f4ca014be3ea606ddfae 387 SUPERFAMILY SSF56300 6 300 2.28E-54 T 23-10-2018 STK_21070 de0ba7a65817f4ca014be3ea606ddfae 387 Gene3D G3DSA:3.60.21.10 4 249 1.5E-54 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like STK_21070 de0ba7a65817f4ca014be3ea606ddfae 387 Pfam PF00149 Calcineurin-like phosphoesterase 5 168 5.4E-12 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 STK_21070 de0ba7a65817f4ca014be3ea606ddfae 387 Hamap MF_02044 DNA double-strand break repair protein Mre11 [mre11]. 4 381 27.551 T 23-10-2018 IPR032885 DNA double-strand break repair protein Mre11, archaea-type GO:0006302 STK_20220 afdca49271bcf3d62eade8c630928a75 199 SUPERFAMILY SSF56281 6 194 2.71E-50 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_20220 afdca49271bcf3d62eade8c630928a75 199 SMART SM00849 13 177 1.8E-36 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_20220 afdca49271bcf3d62eade8c630928a75 199 Gene3D G3DSA:3.60.15.10 1 198 1.7E-58 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_20220 afdca49271bcf3d62eade8c630928a75 199 Pfam PF00753 Metallo-beta-lactamase superfamily 10 177 2.6E-21 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_16510 669c6d7e48d2f2042dbb90f4d99b1be3 1136 SUPERFAMILY SSF82866 563 777 1.96E-27 T 23-10-2018 STK_16510 669c6d7e48d2f2042dbb90f4d99b1be3 1136 SUPERFAMILY SSF82866 968 1128 8.63E-18 T 23-10-2018 STK_16510 669c6d7e48d2f2042dbb90f4d99b1be3 1136 Pfam PF03176 MMPL family 590 785 2.7E-31 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 STK_16510 669c6d7e48d2f2042dbb90f4d99b1be3 1136 Pfam PF03176 MMPL family 920 1127 1.9E-30 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 STK_14130 fbd217df6f5f08bc336674a2b7d1af7c 263 SUPERFAMILY SSF53218 4 206 4.71E-40 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily STK_14130 fbd217df6f5f08bc336674a2b7d1af7c 263 SMART SM00852 7 175 3.4E-35 T 23-10-2018 IPR001453 MoaB/Mog domain STK_14130 fbd217df6f5f08bc336674a2b7d1af7c 263 Hamap MF_00226_A Putative competence-damage inducible protein [cinA]. 4 253 40.994 T 23-10-2018 IPR023055 Putative competence-damage inducible protein, Archaea STK_14130 fbd217df6f5f08bc336674a2b7d1af7c 263 Gene3D G3DSA:3.40.980.10 5 174 9.3E-47 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily STK_14130 fbd217df6f5f08bc336674a2b7d1af7c 263 Pfam PF00994 Probable molybdopterin binding domain 8 173 1.4E-32 T 23-10-2018 IPR001453 MoaB/Mog domain STK_08950 75b63551a4c56360d9fa517092974920 124 Pfam PF05168 HEPN domain 4 119 1.2E-24 T 23-10-2018 IPR007842 HEPN domain STK_08950 75b63551a4c56360d9fa517092974920 124 Gene3D G3DSA:1.20.120.330 2 121 2.8E-17 T 23-10-2018 STK_08950 75b63551a4c56360d9fa517092974920 124 SMART SM00748 6 116 7.2E-31 T 23-10-2018 IPR007842 HEPN domain STK_08950 75b63551a4c56360d9fa517092974920 124 SUPERFAMILY SSF81593 5 118 7.46E-19 T 23-10-2018 STK_08270 238ccbc78cae351d38446476dd4accb8 223 Gene3D G3DSA:3.40.30.10 1 209 1.9E-35 T 23-10-2018 STK_08270 238ccbc78cae351d38446476dd4accb8 223 Pfam PF13743 Thioredoxin 7 185 6.3E-21 T 23-10-2018 STK_08270 238ccbc78cae351d38446476dd4accb8 223 SUPERFAMILY SSF52833 2 209 1.48E-36 T 23-10-2018 IPR036249 Thioredoxin-like superfamily STK_13940 0d2cd41dd9e9e23282b98f23941df29c 288 Gene3D G3DSA:3.50.50.100 2 98 3.7E-6 T 23-10-2018 STK_13940 0d2cd41dd9e9e23282b98f23941df29c 288 Gene3D G3DSA:3.50.50.100 143 287 9.8E-8 T 23-10-2018 STK_13940 0d2cd41dd9e9e23282b98f23941df29c 288 SUPERFAMILY SSF51905 4 223 4.01E-11 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_15850 1ee0023634c221157ca9110698a44530 261 SUPERFAMILY SSF56281 6 223 1.44E-40 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_15850 1ee0023634c221157ca9110698a44530 261 Pfam PF00753 Metallo-beta-lactamase superfamily 19 207 2.2E-21 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_15850 1ee0023634c221157ca9110698a44530 261 SMART SM00849 19 207 6.1E-35 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_15850 1ee0023634c221157ca9110698a44530 261 Gene3D G3DSA:3.60.15.10 1 261 2.9E-110 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_25010 fd035dfa35b15311bff7dd9f3c9e32f6 231 Pfam PF12705 PD-(D/E)XK nuclease superfamily 72 219 2.3E-9 T 23-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type STK_25010 fd035dfa35b15311bff7dd9f3c9e32f6 231 Gene3D G3DSA:3.90.320.10 8 223 6.7E-60 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal STK_25010 fd035dfa35b15311bff7dd9f3c9e32f6 231 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 34 219 4.2E-19 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 STK_22710 500b1aa4a0b390a84860ebc258427228 330 Pfam PF00793 DAHP synthetase I family 80 313 7.8E-73 T 23-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 STK_22710 500b1aa4a0b390a84860ebc258427228 330 SUPERFAMILY SSF51569 47 328 4.12E-100 T 23-10-2018 STK_22710 500b1aa4a0b390a84860ebc258427228 330 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 64 321 2.4E-128 T 23-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 STK_22710 500b1aa4a0b390a84860ebc258427228 330 Gene3D G3DSA:3.20.20.70 52 322 1.1E-103 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_23630 1a8f9ea713915749eb94e9248b002620 494 SUPERFAMILY SSF103473 9 483 4.19E-66 T 23-10-2018 IPR036259 MFS transporter superfamily STK_23630 1a8f9ea713915749eb94e9248b002620 494 ProSitePatterns PS00216 Sugar transport proteins signature 1. 336 352 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 STK_23630 1a8f9ea713915749eb94e9248b002620 494 Pfam PF00083 Sugar (and other) transporter 28 481 1.2E-54 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 STK_23630 1a8f9ea713915749eb94e9248b002620 494 ProSitePatterns PS00217 Sugar transport proteins signature 2. 133 158 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 STK_20030 ad9a3bdf4d51b93086e8b9bfc2821f6d 171 Pfam PF05942 Archaeal PaREP1/PaREP8 family 50 162 8.4E-37 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_20030 ad9a3bdf4d51b93086e8b9bfc2821f6d 171 Gene3D G3DSA:1.20.120.330 50 170 3.0E-38 T 23-10-2018 STK_09040 1b5ed5beb63c3a82bd85a707e1fe3868 423 Pfam PF02687 FtsX-like permease family 287 414 1.3E-13 T 23-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 STK_09040 1b5ed5beb63c3a82bd85a707e1fe3868 423 Pfam PF12704 MacB-like periplasmic core domain 22 230 9.8E-19 T 23-10-2018 IPR025857 MacB-like periplasmic core domain STK_23820 338dd988b4334b0d811d3599da9102f4 289 SUPERFAMILY SSF82861 50 129 5.49E-6 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 STK_23820 338dd988b4334b0d811d3599da9102f4 289 SUPERFAMILY SSF50182 131 199 1.44E-7 T 23-10-2018 IPR010920 LSM domain superfamily STK_23820 338dd988b4334b0d811d3599da9102f4 289 Pfam PF00924 Mechanosensitive ion channel 90 242 8.9E-22 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 STK_12770 e6421b0efe6d9b71d585da20e818763d 249 TIGRFAM TIGR00024 SbcD_rel_arch: putative phosphoesterase 7 241 1.9E-44 T 23-10-2018 IPR004376 Conserved hypothetical protein CHP00024, phosphoesterase-like STK_12770 e6421b0efe6d9b71d585da20e818763d 249 SUPERFAMILY SSF56300 25 242 1.25E-17 T 23-10-2018 STK_12770 e6421b0efe6d9b71d585da20e818763d 249 Pfam PF00149 Calcineurin-like phosphoesterase 25 144 3.0E-6 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 STK_12770 e6421b0efe6d9b71d585da20e818763d 249 PIRSF PIRSF000887 4 249 1.1E-69 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 STK_12770 e6421b0efe6d9b71d585da20e818763d 249 Gene3D G3DSA:3.60.21.10 21 225 5.7E-13 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like STK_00270 a5f8435e28316f71b042dd774c0799fd 288 Gene3D G3DSA:3.90.320.10 115 287 3.4E-5 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal STK_00270 a5f8435e28316f71b042dd774c0799fd 288 TIGRFAM TIGR01896 cas_AF1879: CRISPR-associated protein Cas4/Csa1, subtype I-A/APERN 11 286 1.4E-111 T 23-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 STK_00270 a5f8435e28316f71b042dd774c0799fd 288 PIRSF PIRSF009226 2 287 3.0E-109 T 23-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 STK_00270 a5f8435e28316f71b042dd774c0799fd 288 Pfam PF06023 CRISPR-associated exonuclease Csa1 2 287 4.3E-118 T 23-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 STK_22480 6ee9e97b4b8ec4174bcdfac766989046 366 Pfam PF09376 NurA domain 60 333 4.0E-29 T 23-10-2018 IPR018977 NurA domain STK_22480 6ee9e97b4b8ec4174bcdfac766989046 366 SMART SM00933 59 334 1.4E-29 T 23-10-2018 IPR018977 NurA domain STK_01710 b5a9f607f8fc99df85a5f992848174ea 188 Pfam PF01810 LysE type translocator 15 182 1.3E-9 T 23-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 STK_01520 36281f3c4813e3d1be8c72e34538bec3 381 Pfam PF07282 Putative transposase DNA-binding domain 297 363 2.6E-21 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_01520 36281f3c4813e3d1be8c72e34538bec3 381 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 243 324 1.5E-24 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_05820 9a8f14d86bca004868a3fd4d856c72e1 200 SUPERFAMILY SSF52499 7 194 1.44E-62 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 STK_05820 9a8f14d86bca004868a3fd4d856c72e1 200 Gene3D G3DSA:3.40.50.850 10 198 8.2E-60 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 STK_05820 9a8f14d86bca004868a3fd4d856c72e1 200 Pfam PF00857 Isochorismatase family 21 180 1.0E-41 T 23-10-2018 IPR000868 Isochorismatase-like GO:0003824 STK_15190 1cf59e516f412ac4992192d0e1fa7e02 304 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 178 200 - T 23-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 STK_15190 1cf59e516f412ac4992192d0e1fa7e02 304 Pfam PF00742 Homoserine dehydrogenase 139 297 7.5E-44 T 23-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 STK_15190 1cf59e516f412ac4992192d0e1fa7e02 304 PIRSF PIRSF036497 1 304 3.7E-89 T 23-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 STK_15190 1cf59e516f412ac4992192d0e1fa7e02 304 SUPERFAMILY SSF55347 140 284 3.86E-42 T 23-10-2018 STK_15190 1cf59e516f412ac4992192d0e1fa7e02 304 Gene3D G3DSA:3.30.360.10 144 280 4.6E-110 T 23-10-2018 STK_15190 1cf59e516f412ac4992192d0e1fa7e02 304 Gene3D G3DSA:3.40.50.720 5 297 4.6E-110 T 23-10-2018 STK_15190 1cf59e516f412ac4992192d0e1fa7e02 304 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 7 125 2.5E-9 T 23-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 STK_15190 1cf59e516f412ac4992192d0e1fa7e02 304 SUPERFAMILY SSF51735 1 154 6.9E-21 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_18190 f48c7be096940b3c7211e36e2efe687c 192 Hamap MF_00786 Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) [cbiT]. 8 191 35.487 T 23-10-2018 IPR023475 Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) CbiT GO:0008168 KEGG: 00860+2.1.1.196|MetaCyc: PWY-7377 STK_18190 f48c7be096940b3c7211e36e2efe687c 192 Gene3D G3DSA:3.40.50.150 1 192 1.6E-60 T 23-10-2018 STK_18190 f48c7be096940b3c7211e36e2efe687c 192 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 33 138 1.1E-11 T 23-10-2018 STK_18190 f48c7be096940b3c7211e36e2efe687c 192 SUPERFAMILY SSF53335 19 159 7.91E-31 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_18190 f48c7be096940b3c7211e36e2efe687c 192 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 18 140 1.6E-39 T 23-10-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00860+2.1.1.196|MetaCyc: PWY-7377 STK_15390 c7f64259255235b6aadb25b96bd4cd17 182 Pfam PF06197 Protein of unknown function (DUF998) 10 174 3.3E-30 T 23-10-2018 IPR009339 Protein of unknown function DUF998 STK_25740 3a5344be46b2e578d2e3224f2053f33d 367 Gene3D G3DSA:3.30.1540.10 206 304 5.2E-79 T 23-10-2018 STK_25740 3a5344be46b2e578d2e3224f2053f33d 367 Gene3D G3DSA:3.40.50.10540 3 357 5.2E-79 T 23-10-2018 IPR023606 CoA-transferase family III domain superfamily STK_25740 3a5344be46b2e578d2e3224f2053f33d 367 SUPERFAMILY SSF89796 2 363 1.19E-85 T 23-10-2018 IPR023606 CoA-transferase family III domain superfamily STK_25740 3a5344be46b2e578d2e3224f2053f33d 367 Pfam PF02515 CoA-transferase family III 3 324 7.5E-71 T 23-10-2018 IPR003673 CoA-transferase family III GO:0003824 STK_21570 27d69450aa1501b636934547443394da 169 Hamap MF_00796 Nucleoside-triphosphatase . 5 168 28.265 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 STK_21570 27d69450aa1501b636934547443394da 169 Pfam PF03266 NTPase 6 160 5.8E-51 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 STK_21570 27d69450aa1501b636934547443394da 169 SUPERFAMILY SSF52540 7 162 8.81E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_21570 27d69450aa1501b636934547443394da 169 Gene3D G3DSA:3.40.50.300 5 168 5.1E-38 T 23-10-2018 STK_06100 79131b3c30d9f7332a700ea1df54367d 252 Gene3D G3DSA:3.90.226.10 1 249 1.8E-48 T 23-10-2018 STK_06100 79131b3c30d9f7332a700ea1df54367d 252 SUPERFAMILY SSF52096 3 249 7.57E-48 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily STK_06100 79131b3c30d9f7332a700ea1df54367d 252 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 249 2.2E-35 T 23-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 STK_25790 71a61c4fc4fa286b59b32bb9ce395ecd 173 Pfam PF05942 Archaeal PaREP1/PaREP8 family 19 137 1.7E-26 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_06480 172b7408cb1a66e4371ae445b051b51e 172 Gene3D G3DSA:3.40.50.620 1 172 1.9E-45 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_06480 172b7408cb1a66e4371ae445b051b51e 172 SUPERFAMILY SSF52374 1 165 4.74E-35 T 23-10-2018 STK_06480 172b7408cb1a66e4371ae445b051b51e 172 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 172 79.0 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 STK_06480 172b7408cb1a66e4371ae445b051b51e 172 Pfam PF01467 Cytidylyltransferase-like 4 134 2.7E-13 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 STK_06480 172b7408cb1a66e4371ae445b051b51e 172 TIGRFAM TIGR01527 arch_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 2 168 1.3E-64 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 STK_06480 172b7408cb1a66e4371ae445b051b51e 172 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 2 60 7.2E-15 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 STK_00900 3131d1ca6ff51202da7e5f33f18065a0 546 Gene3D G3DSA:3.20.20.70 1 345 7.7E-101 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_00900 3131d1ca6ff51202da7e5f33f18065a0 546 Gene3D G3DSA:3.40.50.720 355 444 4.6E-22 T 23-10-2018 STK_00900 3131d1ca6ff51202da7e5f33f18065a0 546 SUPERFAMILY SSF51395 3 349 8.31E-97 T 23-10-2018 STK_00900 3131d1ca6ff51202da7e5f33f18065a0 546 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 3 319 7.8E-58 T 23-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 STK_00900 3131d1ca6ff51202da7e5f33f18065a0 546 Pfam PF13450 NAD(P)-binding Rossmann-like domain 362 402 3.8E-8 T 23-10-2018 STK_00900 3131d1ca6ff51202da7e5f33f18065a0 546 SUPERFAMILY SSF51971 321 432 7.06E-16 T 23-10-2018 STK_22410 ec362a60eee2af36fa59a0f4c8d2e0ff 422 SUPERFAMILY SSF53223 10 189 9.92E-64 T 23-10-2018 STK_22410 ec362a60eee2af36fa59a0f4c8d2e0ff 422 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 106 119 - T 23-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 STK_22410 ec362a60eee2af36fa59a0f4c8d2e0ff 422 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 187 420 1.3E-71 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 STK_22410 ec362a60eee2af36fa59a0f4c8d2e0ff 422 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 220 240 2.2E-30 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 STK_22410 ec362a60eee2af36fa59a0f4c8d2e0ff 422 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 347 358 2.2E-30 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 STK_22410 ec362a60eee2af36fa59a0f4c8d2e0ff 422 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 98 112 2.2E-30 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 STK_22410 ec362a60eee2af36fa59a0f4c8d2e0ff 422 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 178 200 2.2E-30 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 STK_22410 ec362a60eee2af36fa59a0f4c8d2e0ff 422 SUPERFAMILY SSF51735 187 421 9.75E-72 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_22410 ec362a60eee2af36fa59a0f4c8d2e0ff 422 SMART SM00839 188 420 3.9E-91 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 STK_22410 ec362a60eee2af36fa59a0f4c8d2e0ff 422 Gene3D G3DSA:3.40.50.10860 43 186 5.6E-59 T 23-10-2018 STK_22410 ec362a60eee2af36fa59a0f4c8d2e0ff 422 PIRSF PIRSF000185 8 422 7.8E-162 T 23-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 STK_22410 ec362a60eee2af36fa59a0f4c8d2e0ff 422 Gene3D G3DSA:3.40.50.720 187 422 8.6E-81 T 23-10-2018 STK_22410 ec362a60eee2af36fa59a0f4c8d2e0ff 422 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 41 167 9.9E-54 T 23-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 STK_13570 f8d4b520733824c378f313b08e4bf174 415 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 21 31 - T 23-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_13570 f8d4b520733824c378f313b08e4bf174 415 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 6 406 34.101 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_13570 f8d4b520733824c378f313b08e4bf174 415 Pfam PF00162 Phosphoglycerate kinase 12 395 8.3E-102 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_13570 f8d4b520733824c378f313b08e4bf174 415 SUPERFAMILY SSF53748 7 404 5.89E-109 T 23-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_13570 f8d4b520733824c378f313b08e4bf174 415 PRINTS PR00477 Phosphoglycerate kinase family signature 16 32 2.2E-58 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_13570 f8d4b520733824c378f313b08e4bf174 415 PRINTS PR00477 Phosphoglycerate kinase family signature 150 172 2.2E-58 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_13570 f8d4b520733824c378f313b08e4bf174 415 PRINTS PR00477 Phosphoglycerate kinase family signature 203 222 2.2E-58 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_13570 f8d4b520733824c378f313b08e4bf174 415 PRINTS PR00477 Phosphoglycerate kinase family signature 115 130 2.2E-58 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_13570 f8d4b520733824c378f313b08e4bf174 415 PRINTS PR00477 Phosphoglycerate kinase family signature 39 61 2.2E-58 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_13570 f8d4b520733824c378f313b08e4bf174 415 PRINTS PR00477 Phosphoglycerate kinase family signature 325 350 2.2E-58 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_13570 f8d4b520733824c378f313b08e4bf174 415 PRINTS PR00477 Phosphoglycerate kinase family signature 382 399 2.2E-58 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_13570 f8d4b520733824c378f313b08e4bf174 415 PRINTS PR00477 Phosphoglycerate kinase family signature 358 369 2.2E-58 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_13570 f8d4b520733824c378f313b08e4bf174 415 PRINTS PR00477 Phosphoglycerate kinase family signature 180 202 2.2E-58 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_13570 f8d4b520733824c378f313b08e4bf174 415 Gene3D G3DSA:3.40.50.1260 16 403 5.7E-119 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_13570 f8d4b520733824c378f313b08e4bf174 415 Gene3D G3DSA:3.40.50.1260 199 396 5.7E-119 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_13570 f8d4b520733824c378f313b08e4bf174 415 PIRSF PIRSF000724 5 413 8.5E-133 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 STK_23565 0d37290942a9b22de6798eed68d1257f 81 SUPERFAMILY SSF101386 3 80 2.04E-18 T 23-10-2018 STK_23565 0d37290942a9b22de6798eed68d1257f 81 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 25 77 4.0E-12 T 23-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core STK_23565 0d37290942a9b22de6798eed68d1257f 81 Gene3D G3DSA:1.10.287.1080 1 81 7.1E-27 T 23-10-2018 STK_01880 560010670b57703d8969aed21cc49ce9 128 TIGRFAM TIGR00307 eS8: ribosomal protein eS8 1 128 7.4E-41 T 23-10-2018 IPR001047 Ribosomal protein S8e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_01880 560010670b57703d8969aed21cc49ce9 128 Hamap MF_00029 30S ribosomal protein S8e [rps8e]. 2 127 32.153 T 23-10-2018 IPR020919 Ribosomal protein S8e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_01880 560010670b57703d8969aed21cc49ce9 128 Pfam PF01201 Ribosomal protein S8e 5 126 3.0E-34 T 23-10-2018 IPR022309 Ribosomal protein S8e/ribosomal biogenesis NSA2 STK_01880 560010670b57703d8969aed21cc49ce9 128 Gene3D G3DSA:2.40.10.310 58 128 3.8E-33 T 23-10-2018 STK_01880 560010670b57703d8969aed21cc49ce9 128 ProSitePatterns PS01193 Ribosomal protein S8e signature. 10 29 - T 23-10-2018 IPR018283 Ribosomal protein S8e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_19390 ad7d0f0d8298d2c053fbf46b3ce8265d 202 ProSitePatterns PS00397 Site-specific recombinases active site. 62 70 - T 23-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 STK_19390 ad7d0f0d8298d2c053fbf46b3ce8265d 202 SMART SM00857 59 192 1.5E-21 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 STK_19390 ad7d0f0d8298d2c053fbf46b3ce8265d 202 SUPERFAMILY SSF46955 3 50 1.95E-8 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily STK_19390 ad7d0f0d8298d2c053fbf46b3ce8265d 202 Pfam PF12728 Helix-turn-helix domain 4 51 1.0E-14 T 23-10-2018 STK_19390 ad7d0f0d8298d2c053fbf46b3ce8265d 202 Gene3D G3DSA:3.40.50.1390 56 156 3.0E-25 T 23-10-2018 STK_19390 ad7d0f0d8298d2c053fbf46b3ce8265d 202 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 50 8.4E-10 T 23-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 STK_19390 ad7d0f0d8298d2c053fbf46b3ce8265d 202 Gene3D G3DSA:1.10.1660.10 2 55 4.0E-6 T 23-10-2018 STK_19390 ad7d0f0d8298d2c053fbf46b3ce8265d 202 Pfam PF00239 Resolvase, N terminal domain 59 184 1.2E-24 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 STK_19390 ad7d0f0d8298d2c053fbf46b3ce8265d 202 SUPERFAMILY SSF53041 58 187 7.85E-22 T 23-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 STK_04150 8f9239dca758924db3da726ac6190adf 196 Hamap MF_01337_A 50S ribosomal protein L18 [rplR]. 5 191 40.558 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04150 8f9239dca758924db3da726ac6190adf 196 Pfam PF14204 Ribosomal L18 C-terminal region 140 192 8.3E-10 T 23-10-2018 IPR025607 Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04150 8f9239dca758924db3da726ac6190adf 196 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 6 96 4.2E-24 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04150 8f9239dca758924db3da726ac6190adf 196 Gene3D G3DSA:3.30.420.100 1 195 2.6E-62 T 23-10-2018 STK_04150 8f9239dca758924db3da726ac6190adf 196 SUPERFAMILY SSF53137 2 193 1.23E-57 T 23-10-2018 STK_17730 99b3cd3a531fc9547132abc126f0b3a9 135 Gene3D G3DSA:1.10.10.10 6 101 3.3E-17 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_17730 99b3cd3a531fc9547132abc126f0b3a9 135 SUPERFAMILY SSF46785 12 130 6.94E-22 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_17730 99b3cd3a531fc9547132abc126f0b3a9 135 Pfam PF03551 Transcriptional regulator PadR-like family 16 80 2.3E-10 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal STK_26040 3c7f5eaa50e8b35ed798e9fffc198749 480 Pfam PF07690 Major Facilitator Superfamily 12 409 1.4E-38 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_26040 3c7f5eaa50e8b35ed798e9fffc198749 480 Gene3D G3DSA:1.20.1250.20 254 472 7.8E-16 T 23-10-2018 STK_26040 3c7f5eaa50e8b35ed798e9fffc198749 480 SUPERFAMILY SSF103473 3 472 2.62E-56 T 23-10-2018 IPR036259 MFS transporter superfamily STK_26040 3c7f5eaa50e8b35ed798e9fffc198749 480 Gene3D G3DSA:1.20.1720.10 9 210 5.2E-37 T 23-10-2018 STK_26040 3c7f5eaa50e8b35ed798e9fffc198749 480 PRINTS PR01036 Tetracycline resistance protein TetB signature 360 380 4.3E-5 T 23-10-2018 STK_26040 3c7f5eaa50e8b35ed798e9fffc198749 480 PRINTS PR01036 Tetracycline resistance protein TetB signature 227 245 4.3E-5 T 23-10-2018 STK_26040 3c7f5eaa50e8b35ed798e9fffc198749 480 PRINTS PR01036 Tetracycline resistance protein TetB signature 11 35 4.3E-5 T 23-10-2018 STK_20350 d27253abf6e60f4c0ea1b9b1be3d8218 203 SUPERFAMILY SSF52540 6 200 1.41E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_20350 d27253abf6e60f4c0ea1b9b1be3d8218 203 SMART SM00382 21 200 7.1E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_20350 d27253abf6e60f4c0ea1b9b1be3d8218 203 Pfam PF00005 ABC transporter 15 150 2.9E-23 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_20350 d27253abf6e60f4c0ea1b9b1be3d8218 203 Gene3D G3DSA:3.40.50.300 4 202 1.7E-36 T 23-10-2018 STK_16320 584323df9109bcf48e7fab7fe2b8823f 159 SUPERFAMILY SSF51283 1 156 5.89E-29 T 23-10-2018 IPR036157 dUTPase-like superfamily STK_16320 584323df9109bcf48e7fab7fe2b8823f 159 Gene3D G3DSA:2.70.40.10 1 141 3.2E-40 T 23-10-2018 IPR036157 dUTPase-like superfamily STK_16320 584323df9109bcf48e7fab7fe2b8823f 159 Pfam PF00692 dUTPase 56 146 2.3E-9 T 23-10-2018 IPR029054 dUTPase-like STK_10560 a9b6669e22cf3893b0871ffcc1d3ef30 428 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 261 339 2.1E-17 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_10560 a9b6669e22cf3893b0871ffcc1d3ef30 428 Pfam PF01385 Probable transposase 191 296 5.3E-13 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 STK_10560 a9b6669e22cf3893b0871ffcc1d3ef30 428 Pfam PF07282 Putative transposase DNA-binding domain 312 377 1.4E-21 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_08300 43793a814d9c1007f7aed406d2338792 378 Pfam PF00092 von Willebrand factor type A domain 41 183 4.1E-17 T 23-10-2018 IPR002035 von Willebrand factor, type A STK_08300 43793a814d9c1007f7aed406d2338792 378 SUPERFAMILY SSF53300 38 192 1.09E-29 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily STK_08300 43793a814d9c1007f7aed406d2338792 378 SMART SM00327 37 199 1.3E-17 T 23-10-2018 IPR002035 von Willebrand factor, type A STK_08300 43793a814d9c1007f7aed406d2338792 378 Gene3D G3DSA:3.40.50.410 39 203 4.2E-33 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily STK_05800 ae6a76abc81971d89b01ce0eeeee95d7 156 Pfam PF00782 Dual specificity phosphatase, catalytic domain 83 146 1.4E-10 T 23-10-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 STK_05800 ae6a76abc81971d89b01ce0eeeee95d7 156 Gene3D G3DSA:3.90.190.10 1 156 1.4E-39 T 23-10-2018 IPR029021 Protein-tyrosine phosphatase-like STK_05800 ae6a76abc81971d89b01ce0eeeee95d7 156 SMART SM00195 30 148 0.0039 T 23-10-2018 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 STK_05800 ae6a76abc81971d89b01ce0eeeee95d7 156 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 93 103 - T 23-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 STK_05800 ae6a76abc81971d89b01ce0eeeee95d7 156 PRINTS PR00700 Protein tyrosine phosphatase signature 132 142 1.9E-7 T 23-10-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 STK_05800 ae6a76abc81971d89b01ce0eeeee95d7 156 PRINTS PR00700 Protein tyrosine phosphatase signature 90 108 1.9E-7 T 23-10-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 STK_05800 ae6a76abc81971d89b01ce0eeeee95d7 156 PRINTS PR00700 Protein tyrosine phosphatase signature 116 131 1.9E-7 T 23-10-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 STK_05800 ae6a76abc81971d89b01ce0eeeee95d7 156 SUPERFAMILY SSF52799 2 148 3.94E-34 T 23-10-2018 IPR029021 Protein-tyrosine phosphatase-like STK_05800 ae6a76abc81971d89b01ce0eeeee95d7 156 SMART SM00404 60 148 3.8E-8 T 23-10-2018 IPR003595 Protein-tyrosine phosphatase, catalytic STK_11110 0f416bcd56a001d251c71b71c3956ce6 116 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 52 101 6.8E-8 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal STK_11110 0f416bcd56a001d251c71b71c3956ce6 116 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 20 48 5.7E-8 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal STK_11110 0f416bcd56a001d251c71b71c3956ce6 116 SUPERFAMILY SSF50249 7 107 1.88E-22 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_03330 4bc65cb282c0a153fbff81094dcafa3c 169 SUPERFAMILY SSF75217 2 166 9.68E-63 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases STK_03330 4bc65cb282c0a153fbff81094dcafa3c 169 Hamap MF_00077 tRNA (cytidine(56)-2'-O)-methyltransferase. 1 168 37.516 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 STK_03330 4bc65cb282c0a153fbff81094dcafa3c 169 Pfam PF01994 tRNA ribose 2'-O-methyltransferase, aTrm56 47 165 2.7E-50 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 STK_03330 4bc65cb282c0a153fbff81094dcafa3c 169 PIRSF PIRSF016123 1 169 2.5E-74 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 STK_03330 4bc65cb282c0a153fbff81094dcafa3c 169 Gene3D G3DSA:3.40.1280.10 1 169 5.1E-68 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal STK_03330 4bc65cb282c0a153fbff81094dcafa3c 169 ProDom PD016584 UPF0106 MK0803 MM0086 METAL MA3241 UNCHARACTERIZED DOMAIN TA0931 APE2006 ST0333 47 169 1.0E-66 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 STK_13650 3c6f9bb922be835a5f53f0b79b7c085a 105 Gene3D G3DSA:1.10.10.1410 1 58 1.3E-27 T 23-10-2018 IPR038716 Ribosomal protein P1/P2, N-terminal domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_13650 3c6f9bb922be835a5f53f0b79b7c085a 105 Hamap MF_01478 50S ribosomal protein L12 [rpl12]. 1 102 13.44 T 23-10-2018 IPR027534 Ribosomal protein L12 family GO:0003735|GO:0005622|GO:0005840|GO:0006414 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_13650 3c6f9bb922be835a5f53f0b79b7c085a 105 TIGRFAM TIGR03685 ribo_P1_arch: 50S ribosomal protein P1 1 105 6.6E-45 T 23-10-2018 IPR022295 Ribosomal protein L12, archaea GO:0003735|GO:0005840|GO:0006414 STK_13650 3c6f9bb922be835a5f53f0b79b7c085a 105 Pfam PF00428 60s Acidic ribosomal protein 16 100 7.9E-21 T 23-10-2018 STK_25290 55744532317562808a08c6da0417e080 836 Gene3D G3DSA:1.50.10.10 414 546 2.2E-5 T 23-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 STK_25290 55744532317562808a08c6da0417e080 836 Pfam PF12215 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term 12 145 1.7E-20 T 23-10-2018 IPR024462 Glycosyl-hydrolase family 116, N-terminal KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 STK_25290 55744532317562808a08c6da0417e080 836 SUPERFAMILY SSF48208 435 823 2.3E-22 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 STK_25290 55744532317562808a08c6da0417e080 836 Pfam PF04685 Glycosyl-hydrolase family 116, catalytic region 542 744 7.2E-24 T 23-10-2018 IPR006775 Glycosyl-hydrolase family 116, catalytic region GO:0004553 KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 STK_22270 fdd72fb87c7eeda8d3814dddfa34dabd 189 SUPERFAMILY SSF55729 1 166 4.08E-19 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase STK_22270 fdd72fb87c7eeda8d3814dddfa34dabd 189 Pfam PF00583 Acetyltransferase (GNAT) family 38 140 1.1E-9 T 23-10-2018 IPR000182 GNAT domain STK_22270 fdd72fb87c7eeda8d3814dddfa34dabd 189 Gene3D G3DSA:3.40.630.30 2 167 2.8E-18 T 23-10-2018 STK_11490 9822d21204ab8a51695343cbb373bbd0 267 Pfam PF06267 Family of unknown function (DUF1028) 2 199 2.8E-70 T 23-10-2018 IPR010430 Protein of unknown function DUF1028 STK_11490 9822d21204ab8a51695343cbb373bbd0 267 Pfam PF08823 Putative peptidoglycan binding domain 213 263 9.4E-12 T 23-10-2018 IPR014927 Putative peptidoglycan binding STK_11490 9822d21204ab8a51695343cbb373bbd0 267 Gene3D G3DSA:3.60.20.10 1 221 1.0E-72 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_11490 9822d21204ab8a51695343cbb373bbd0 267 SUPERFAMILY SSF56235 2 221 5.17E-64 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_07000 60cf9ca9d991f9d29e5ff68b3e9328fa 313 SMART SM00382 33 228 9.6E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_07000 60cf9ca9d991f9d29e5ff68b3e9328fa 313 Pfam PF00005 ABC transporter 24 178 2.2E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_07000 60cf9ca9d991f9d29e5ff68b3e9328fa 313 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 292 5.8E-16 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 STK_07000 60cf9ca9d991f9d29e5ff68b3e9328fa 313 SUPERFAMILY SSF52540 4 250 1.46E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_07000 60cf9ca9d991f9d29e5ff68b3e9328fa 313 Gene3D G3DSA:3.40.50.300 1 313 4.4E-94 T 23-10-2018 STK_07000 60cf9ca9d991f9d29e5ff68b3e9328fa 313 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 STK_07000 60cf9ca9d991f9d29e5ff68b3e9328fa 313 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 228 312 2.4E-22 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 STK_17270 69545717f1d9df2f9e8fd2aed5069691 103 ProDom PD068622 ORF A102B B98 C-102A ST1727 5 103 2.0E-43 T 23-10-2018 IPR020512 Sulfolobus virus-like particle SSV1, p18 STK_23070 3b328c62dc9ec988bfbafe1f8cca588d 400 Hamap MF_01643 Formate-dependent phosphoribosylglycinamide formyltransferase [purT]. 10 400 47.273 T 23-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 STK_23070 3b328c62dc9ec988bfbafe1f8cca588d 400 Gene3D G3DSA:3.30.1490.20 127 198 2.2E-26 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 STK_23070 3b328c62dc9ec988bfbafe1f8cca588d 400 SUPERFAMILY SSF52440 6 114 2.59E-33 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily STK_23070 3b328c62dc9ec988bfbafe1f8cca588d 400 Pfam PF02222 ATP-grasp domain 125 302 9.5E-43 T 23-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type STK_23070 3b328c62dc9ec988bfbafe1f8cca588d 400 SUPERFAMILY SSF56059 121 393 4.78E-56 T 23-10-2018 STK_23070 3b328c62dc9ec988bfbafe1f8cca588d 400 Gene3D G3DSA:3.30.470.20 199 400 1.6E-55 T 23-10-2018 STK_23070 3b328c62dc9ec988bfbafe1f8cca588d 400 Gene3D G3DSA:3.40.50.20 2 126 1.6E-48 T 23-10-2018 STK_01950 00a1bbcc29c57275c3368d2efd5f56a9 349 SUPERFAMILY SSF51735 2 174 7.45E-53 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_01950 00a1bbcc29c57275c3368d2efd5f56a9 349 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 348 2.6E-129 T 23-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 STK_01950 00a1bbcc29c57275c3368d2efd5f56a9 349 Hamap MF_02083 [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase [lysY]. 2 348 53.548 T 23-10-2018 IPR037535 [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase GO:0016620 STK_01950 00a1bbcc29c57275c3368d2efd5f56a9 349 Gene3D G3DSA:3.30.360.10 148 316 1.8E-110 T 23-10-2018 STK_01950 00a1bbcc29c57275c3368d2efd5f56a9 349 SMART SM00859 3 142 6.8E-57 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 STK_01950 00a1bbcc29c57275c3368d2efd5f56a9 349 Gene3D G3DSA:3.40.50.720 3 333 1.8E-110 T 23-10-2018 STK_01950 00a1bbcc29c57275c3368d2efd5f56a9 349 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 142 6.9E-35 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 STK_01950 00a1bbcc29c57275c3368d2efd5f56a9 349 SUPERFAMILY SSF55347 150 316 5.36E-39 T 23-10-2018 STK_01950 00a1bbcc29c57275c3368d2efd5f56a9 349 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 183 319 3.4E-7 T 23-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 STK_01950 00a1bbcc29c57275c3368d2efd5f56a9 349 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 342 40.659 T 23-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 STK_02990 e833c6970666f320ac1b082a630c14d8 335 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 63 334 5.1E-85 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 STK_02990 e833c6970666f320ac1b082a630c14d8 335 SUPERFAMILY SSF53335 24 334 4.1E-67 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_02990 e833c6970666f320ac1b082a630c14d8 335 Gene3D G3DSA:3.30.70.3130 16 125 1.3E-30 T 23-10-2018 STK_02990 e833c6970666f320ac1b082a630c14d8 335 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 112 126 9.5E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase STK_02990 e833c6970666f320ac1b082a630c14d8 335 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 317 334 9.5E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase STK_02990 e833c6970666f320ac1b082a630c14d8 335 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 207 219 9.5E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase STK_02990 e833c6970666f320ac1b082a630c14d8 335 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 257 273 9.5E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase STK_02990 e833c6970666f320ac1b082a630c14d8 335 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 141 151 9.5E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase STK_02990 e833c6970666f320ac1b082a630c14d8 335 Pfam PF01189 16S rRNA methyltransferase RsmB/F 130 332 7.4E-53 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 STK_02990 e833c6970666f320ac1b082a630c14d8 335 Gene3D G3DSA:3.40.50.150 129 335 1.4E-65 T 23-10-2018 STK_02990 e833c6970666f320ac1b082a630c14d8 335 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 36 126 2.5E-16 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 STK_20840 7b365b3dbe6f95c05f4afdaa6e51ce12 515 SUPERFAMILY SSF47413 4 67 4.22E-19 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 STK_20840 7b365b3dbe6f95c05f4afdaa6e51ce12 515 SUPERFAMILY SSF53335 283 399 7.01E-11 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_20840 7b365b3dbe6f95c05f4afdaa6e51ce12 515 Pfam PF01381 Helix-turn-helix 11 63 2.3E-16 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 STK_20840 7b365b3dbe6f95c05f4afdaa6e51ce12 515 Gene3D G3DSA:1.10.260.40 2 73 1.4E-19 T 23-10-2018 STK_20840 7b365b3dbe6f95c05f4afdaa6e51ce12 515 SMART SM00530 8 63 6.7E-16 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 STK_20840 7b365b3dbe6f95c05f4afdaa6e51ce12 515 Gene3D G3DSA:2.60.120.10 77 171 2.3E-11 T 23-10-2018 IPR014710 RmlC-like jelly roll fold STK_20840 7b365b3dbe6f95c05f4afdaa6e51ce12 515 SUPERFAMILY SSF51182 82 160 2.46E-8 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily STK_20840 7b365b3dbe6f95c05f4afdaa6e51ce12 515 Gene3D G3DSA:3.40.50.150 263 447 2.4E-6 T 23-10-2018 STK_11990 6996a8f49b0a5e699860cf31e325c0a1 384 Pfam PF01458 Uncharacterized protein family (UPF0051) 142 357 3.5E-37 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 STK_11990 6996a8f49b0a5e699860cf31e325c0a1 384 SUPERFAMILY SSF101960 11 375 3.27E-54 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily STK_11150 91c740daef349275fea6f945cc2142b5 151 SUPERFAMILY SSF54909 74 145 1.47E-12 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel STK_11150 91c740daef349275fea6f945cc2142b5 151 SUPERFAMILY SSF46785 1 59 3.48E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_11150 91c740daef349275fea6f945cc2142b5 151 SMART SM00344 1 109 1.3E-27 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 STK_11150 91c740daef349275fea6f945cc2142b5 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 5.5E-9 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_11150 91c740daef349275fea6f945cc2142b5 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 5.5E-9 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_11150 91c740daef349275fea6f945cc2142b5 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 5.5E-9 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_11150 91c740daef349275fea6f945cc2142b5 151 Gene3D G3DSA:1.10.10.10 1 52 1.6E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_11150 91c740daef349275fea6f945cc2142b5 151 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 3.2E-14 T 23-10-2018 STK_11150 91c740daef349275fea6f945cc2142b5 151 Gene3D G3DSA:3.30.70.920 53 150 3.3E-21 T 23-10-2018 STK_11150 91c740daef349275fea6f945cc2142b5 151 Pfam PF01037 Lrp/AsnC ligand binding domain 66 139 1.1E-12 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain STK_03900 b49374ea4efcb42986a04ae3997582f3 255 PIRSF PIRSF014484 1 254 5.0E-117 T 23-10-2018 IPR009198 Uncharacterised conserved protein UCP014484, transmembrane STK_03900 b49374ea4efcb42986a04ae3997582f3 255 Pfam PF09973 Predicted membrane protein (DUF2208) 15 242 1.5E-72 T 23-10-2018 IPR009198 Uncharacterised conserved protein UCP014484, transmembrane STK_18755 4ba32ae4765d1add0c09bf272ebc3072 79 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 10 34 - T 23-10-2018 IPR001455 TusA-like domain STK_18755 4ba32ae4765d1add0c09bf272ebc3072 79 Gene3D G3DSA:3.30.110.40 2 79 1.9E-30 T 23-10-2018 IPR036868 TusA-like domain superfamily STK_18755 4ba32ae4765d1add0c09bf272ebc3072 79 SUPERFAMILY SSF64307 2 77 6.02E-25 T 23-10-2018 IPR036868 TusA-like domain superfamily STK_18755 4ba32ae4765d1add0c09bf272ebc3072 79 Pfam PF01206 Sulfurtransferase TusA 8 77 1.6E-23 T 23-10-2018 IPR001455 TusA-like domain STK_22620 0581ca2ec98469c2ecbaacce45c89f4a 189 Gene3D G3DSA:2.40.50.100 6 55 2.3E-14 T 23-10-2018 STK_22620 0581ca2ec98469c2ecbaacce45c89f4a 189 Hamap MF_00975 Exosome complex component Csl4 [csl4]. 7 185 22.872 T 23-10-2018 IPR030850 Exosome complex component Csl4, archaea GO:0000178|GO:0006396 STK_22620 0581ca2ec98469c2ecbaacce45c89f4a 189 SUPERFAMILY SSF110324 7 57 9.94E-13 T 23-10-2018 STK_22620 0581ca2ec98469c2ecbaacce45c89f4a 189 SUPERFAMILY SSF50249 68 178 5.88E-20 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_22620 0581ca2ec98469c2ecbaacce45c89f4a 189 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 9 39 3.8E-11 T 23-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 STK_22620 0581ca2ec98469c2ecbaacce45c89f4a 189 Gene3D G3DSA:2.40.50.140 61 146 2.0E-16 T 23-10-2018 STK_22620 0581ca2ec98469c2ecbaacce45c89f4a 189 Gene3D G3DSA:2.20.70.10 147 181 1.3E-10 T 23-10-2018 STK_22510 6336e092bf854472405eebbda5efb0b6 309 Gene3D G3DSA:3.10.129.10 162 309 1.9E-32 T 23-10-2018 STK_22510 6336e092bf854472405eebbda5efb0b6 309 Gene3D G3DSA:3.10.129.10 1 150 1.2E-31 T 23-10-2018 STK_22510 6336e092bf854472405eebbda5efb0b6 309 SUPERFAMILY SSF54637 2 143 1.41E-31 T 23-10-2018 IPR029069 HotDog domain superfamily STK_22510 6336e092bf854472405eebbda5efb0b6 309 SUPERFAMILY SSF54637 165 307 8.88E-30 T 23-10-2018 IPR029069 HotDog domain superfamily STK_22510 6336e092bf854472405eebbda5efb0b6 309 Pfam PF03061 Thioesterase superfamily 183 255 3.7E-8 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 STK_22510 6336e092bf854472405eebbda5efb0b6 309 Pfam PF03061 Thioesterase superfamily 23 98 1.7E-9 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 STK_14200 d240221fce51969f3517d6583841b2d4 377 PIRSF PIRSF016495 5 377 2.3E-174 T 23-10-2018 IPR009995 Protein of unknown function DUF1512 STK_14200 d240221fce51969f3517d6583841b2d4 377 Pfam PF07431 Protein of unknown function (DUF1512) 22 376 1.3E-147 T 23-10-2018 IPR009995 Protein of unknown function DUF1512 STK_22180 68427b743fb74d9d87389d1dacf8aab4 404 SUPERFAMILY SSF56762 34 404 1.31E-110 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_22180 68427b743fb74d9d87389d1dacf8aab4 404 Gene3D G3DSA:1.10.645.20 22 404 1.4E-133 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_22180 68427b743fb74d9d87389d1dacf8aab4 404 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 57 68 - T 23-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_22180 68427b743fb74d9d87389d1dacf8aab4 404 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 135 404 5.1E-93 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_05330 8eed2aa91529134a7540cf3a2097f892 267 PIRSF PIRSF000388 1 265 4.5E-107 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 STK_05330 8eed2aa91529134a7540cf3a2097f892 267 Pfam PF02548 Ketopantoate hydroxymethyltransferase 3 258 1.1E-107 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 STK_05330 8eed2aa91529134a7540cf3a2097f892 267 Gene3D G3DSA:3.20.20.60 1 267 1.4E-107 T 23-10-2018 STK_05330 8eed2aa91529134a7540cf3a2097f892 267 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 263 40.783 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 STK_05330 8eed2aa91529134a7540cf3a2097f892 267 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 5 261 7.6E-95 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 STK_05330 8eed2aa91529134a7540cf3a2097f892 267 SUPERFAMILY SSF51621 3 262 1.06E-100 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 STK_02020 cdf8086ca90c7e2750a3513bdf771795 541 SUPERFAMILY SSF52467 197 384 8.02E-42 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily STK_02020 cdf8086ca90c7e2750a3513bdf771795 541 Gene3D G3DSA:3.40.50.1220 197 360 3.8E-43 T 23-10-2018 STK_02020 cdf8086ca90c7e2750a3513bdf771795 541 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 203 338 1.9E-34 T 23-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 STK_02020 cdf8086ca90c7e2750a3513bdf771795 541 SUPERFAMILY SSF52518 8 194 1.13E-21 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold STK_02020 cdf8086ca90c7e2750a3513bdf771795 541 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 16 181 8.0E-23 T 23-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 STK_02020 cdf8086ca90c7e2750a3513bdf771795 541 Gene3D G3DSA:3.40.50.970 6 193 3.7E-24 T 23-10-2018 STK_18640 ff190eebb7bcf40b5da5b56ec780194d 429 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 1 422 3.2E-153 T 23-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 STK_18640 ff190eebb7bcf40b5da5b56ec780194d 429 Gene3D G3DSA:3.20.20.540 42 361 1.6E-130 T 23-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 STK_18640 ff190eebb7bcf40b5da5b56ec780194d 429 Pfam PF01964 Radical SAM ThiC family 4 419 1.3E-164 T 23-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 STK_18640 ff190eebb7bcf40b5da5b56ec780194d 429 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 1 426 82.097 T 23-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 STK_03300 6fa618476499fefd52434d09a1185d96 392 SUPERFAMILY SSF52540 129 376 4.27E-71 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_03300 6fa618476499fefd52434d09a1185d96 392 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 171 304 1.8E-42 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_03300 6fa618476499fefd52434d09a1185d96 392 Gene3D G3DSA:3.40.50.300 124 304 4.7E-69 T 23-10-2018 STK_03300 6fa618476499fefd52434d09a1185d96 392 Hamap MF_00553 Proteasome-activating nucleotidase [pan]. 1 391 43.682 T 23-10-2018 IPR023501 Proteasome-activating nucleotidase PAN STK_03300 6fa618476499fefd52434d09a1185d96 392 ProSitePatterns PS00674 AAA-protein family signature. 274 292 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 STK_03300 6fa618476499fefd52434d09a1185d96 392 Gene3D G3DSA:2.40.50.140 20 123 1.0E-22 T 23-10-2018 STK_03300 6fa618476499fefd52434d09a1185d96 392 Gene3D G3DSA:1.10.8.60 305 376 9.1E-23 T 23-10-2018 STK_03300 6fa618476499fefd52434d09a1185d96 392 SMART SM00382 167 306 1.6E-23 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_03300 6fa618476499fefd52434d09a1185d96 392 TIGRFAM TIGR01242 26Sp45: 26S proteasome subunit P45 family 20 376 2.1E-174 T 23-10-2018 IPR005937 26S proteasome regulatory subunit P45-like GO:0005737|GO:0016787|GO:0030163 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 STK_10840 d544d9ce2a6f0cdd0c0816fab429f6a9 108 SUPERFAMILY SSF75169 1 108 3.79E-20 T 23-10-2018 IPR027396 DsrEFH-like STK_10840 d544d9ce2a6f0cdd0c0816fab429f6a9 108 Pfam PF02635 DsrE/DsrF-like family 31 107 7.2E-6 T 23-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein STK_10840 d544d9ce2a6f0cdd0c0816fab429f6a9 108 Gene3D G3DSA:3.40.1260.10 15 107 3.2E-7 T 23-10-2018 IPR027396 DsrEFH-like STK_02580 6f65ed2dd64291023a85f207d02c9cca 167 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 21 163 6.9E-31 T 23-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 STK_02580 6f65ed2dd64291023a85f207d02c9cca 167 SUPERFAMILY SSF55729 12 166 2.4E-35 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase STK_02580 6f65ed2dd64291023a85f207d02c9cca 167 Gene3D G3DSA:3.40.630.30 1 167 1.1E-55 T 23-10-2018 STK_02580 6f65ed2dd64291023a85f207d02c9cca 167 Pfam PF00583 Acetyltransferase (GNAT) family 45 144 1.8E-20 T 23-10-2018 IPR000182 GNAT domain STK_09160 84e75f5538bb8445dcb969dfa36571dd 358 SUPERFAMILY SSF56645 5 210 4.58E-36 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 STK_09160 84e75f5538bb8445dcb969dfa36571dd 358 Gene3D G3DSA:1.10.540.10 1 104 3.3E-18 T 23-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 STK_09160 84e75f5538bb8445dcb969dfa36571dd 358 Gene3D G3DSA:2.40.110.10 113 212 6.7E-16 T 23-10-2018 STK_09160 84e75f5538bb8445dcb969dfa36571dd 358 Gene3D G3DSA:1.20.140.10 222 354 3.9E-29 T 23-10-2018 STK_09160 84e75f5538bb8445dcb969dfa36571dd 358 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 107 3.2E-9 T 23-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 STK_09160 84e75f5538bb8445dcb969dfa36571dd 358 PIRSF PIRSF016578 2 357 4.5E-26 T 23-10-2018 STK_09160 84e75f5538bb8445dcb969dfa36571dd 358 SUPERFAMILY SSF47203 224 356 4.51E-29 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 STK_09160 84e75f5538bb8445dcb969dfa36571dd 358 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 338 4.0E-21 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 STK_09160 84e75f5538bb8445dcb969dfa36571dd 358 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 114 201 8.4E-13 T 23-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 STK_20590 b12a72c201dd47c9d090b496c9763ee5 369 Gene3D G3DSA:3.20.20.70 4 368 2.5E-125 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_20590 b12a72c201dd47c9d090b496c9763ee5 369 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 8 344 1.3E-134 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 STK_20590 b12a72c201dd47c9d090b496c9763ee5 369 SMART SM01240 27 347 0.0067 T 23-10-2018 STK_20590 b12a72c201dd47c9d090b496c9763ee5 369 Pfam PF01070 FMN-dependent dehydrogenase 178 339 1.8E-14 T 23-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 STK_20590 b12a72c201dd47c9d090b496c9763ee5 369 PIRSF PIRSF003314 3 355 2.0E-132 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 STK_20590 b12a72c201dd47c9d090b496c9763ee5 369 SUPERFAMILY SSF51395 27 362 8.7E-74 T 23-10-2018 STK_20590 b12a72c201dd47c9d090b496c9763ee5 369 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 6 344 41.396 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 STK_26190 8936ad011471fbba0d9c7bddc9b5e71b 115 Pfam PF05168 HEPN domain 2 113 9.4E-27 T 23-10-2018 IPR007842 HEPN domain STK_26190 8936ad011471fbba0d9c7bddc9b5e71b 115 Gene3D G3DSA:1.20.120.330 1 115 2.5E-20 T 23-10-2018 STK_26190 8936ad011471fbba0d9c7bddc9b5e71b 115 SUPERFAMILY SSF81593 4 113 4.71E-27 T 23-10-2018 STK_26190 8936ad011471fbba0d9c7bddc9b5e71b 115 SMART SM00748 5 108 4.7E-36 T 23-10-2018 IPR007842 HEPN domain STK_24010 3a7c94339dde02e3dc3be213d9c9349e 529 SUPERFAMILY SSF102114 203 444 2.62E-14 T 23-10-2018 STK_24010 3a7c94339dde02e3dc3be213d9c9349e 529 Gene3D G3DSA:3.80.30.20 212 428 6.2E-23 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe STK_24010 3a7c94339dde02e3dc3be213d9c9349e 529 SMART SM00729 212 445 1.4E-16 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 STK_24010 3a7c94339dde02e3dc3be213d9c9349e 529 Pfam PF04055 Radical SAM superfamily 217 399 4.2E-14 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_08150 f9571a3c2906bb7baefa6484b4a09362 615 Pfam PF00723 Glycosyl hydrolases family 15 273 558 4.4E-16 T 23-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 STK_08150 f9571a3c2906bb7baefa6484b4a09362 615 SUPERFAMILY SSF48208 228 611 9.45E-114 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 STK_08150 f9571a3c2906bb7baefa6484b4a09362 615 Gene3D G3DSA:1.50.10.10 255 614 1.6E-88 T 23-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 STK_01110 7a0295a8a7395a1ba443a891970683d7 118 SUPERFAMILY SSF75169 1 95 7.77E-7 T 23-10-2018 IPR027396 DsrEFH-like STK_22520 406fd2f8e170aee034ad6624943e2816 332 Pfam PF00107 Zinc-binding dehydrogenase 177 290 1.5E-24 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 STK_22520 406fd2f8e170aee034ad6624943e2816 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 135 3.3E-27 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 STK_22520 406fd2f8e170aee034ad6624943e2816 332 Gene3D G3DSA:3.90.180.10 3 332 1.0E-82 T 23-10-2018 STK_22520 406fd2f8e170aee034ad6624943e2816 332 SUPERFAMILY SSF50129 3 177 1.83E-44 T 23-10-2018 IPR011032 GroES-like superfamily STK_22520 406fd2f8e170aee034ad6624943e2816 332 SMART SM00829 12 329 1.4E-9 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 STK_22520 406fd2f8e170aee034ad6624943e2816 332 SUPERFAMILY SSF51735 141 304 4.04E-37 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_12490 e56f48ddcba94e0a9325dc7e12d97168 259 Gene3D G3DSA:1.10.10.10 15 163 6.2E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_12490 e56f48ddcba94e0a9325dc7e12d97168 259 SUPERFAMILY SSF46785 49 116 2.51E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_01560 5d8cc2d5062a77d5ffadfedb02fc07fb 437 SMART SM01230 113 355 2.5E-100 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 STK_01560 5d8cc2d5062a77d5ffadfedb02fc07fb 437 Pfam PF00120 Glutamine synthetase, catalytic domain 114 434 4.9E-106 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 STK_01560 5d8cc2d5062a77d5ffadfedb02fc07fb 437 Pfam PF16952 Glutamine synthetase N-terminal domain 12 95 3.8E-9 T 23-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 STK_01560 5d8cc2d5062a77d5ffadfedb02fc07fb 437 SUPERFAMILY SSF54368 14 106 4.97E-10 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 STK_01560 5d8cc2d5062a77d5ffadfedb02fc07fb 437 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 231 246 - T 23-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 STK_01560 5d8cc2d5062a77d5ffadfedb02fc07fb 437 Gene3D G3DSA:3.10.20.70 18 106 7.1E-9 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 STK_01560 5d8cc2d5062a77d5ffadfedb02fc07fb 437 Gene3D G3DSA:3.30.590.10 116 436 5.6E-113 T 23-10-2018 STK_01560 5d8cc2d5062a77d5ffadfedb02fc07fb 437 SUPERFAMILY SSF55931 114 434 7.06E-104 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 STK_13910 3dd0a9ed9704efe7ddc53dca5c7f6936 170 Gene3D G3DSA:2.160.10.10 1 170 2.1E-62 T 23-10-2018 STK_13910 3dd0a9ed9704efe7ddc53dca5c7f6936 170 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 45 1.1E-5 T 23-10-2018 IPR001451 Hexapeptide repeat STK_13910 3dd0a9ed9704efe7ddc53dca5c7f6936 170 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 122 5.6E-9 T 23-10-2018 IPR001451 Hexapeptide repeat STK_13910 3dd0a9ed9704efe7ddc53dca5c7f6936 170 SUPERFAMILY SSF51161 6 168 8.18E-50 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily STK_20710 3c019992c14d188e6a24868fcd404be2 422 PIRSF PIRSF006346 1 422 2.4E-194 T 23-10-2018 IPR009186 Predicted nickel metalloenzyme maturation factor, AIR synthase-related STK_20710 3c019992c14d188e6a24868fcd404be2 422 Pfam PF02769 AIR synthase related protein, C-terminal domain 217 359 3.8E-10 T 23-10-2018 IPR010918 PurM-like, C-terminal domain STK_20710 3c019992c14d188e6a24868fcd404be2 422 Gene3D G3DSA:3.90.650.10 210 375 6.5E-14 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily STK_20710 3c019992c14d188e6a24868fcd404be2 422 Gene3D G3DSA:3.30.1330.10 89 208 1.5E-12 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily STK_20710 3c019992c14d188e6a24868fcd404be2 422 SUPERFAMILY SSF55326 101 207 1.83E-14 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily STK_20710 3c019992c14d188e6a24868fcd404be2 422 SUPERFAMILY SSF56042 211 366 4.34E-17 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily STK_20710 3c019992c14d188e6a24868fcd404be2 422 Pfam PF00586 AIR synthase related protein, N-terminal domain 104 205 1.1E-6 T 23-10-2018 IPR016188 PurM-like, N-terminal domain STK_12690 024ccb915cf9fd022461a2d7350a3454 374 Gene3D G3DSA:3.30.56.70 320 374 5.7E-9 T 23-10-2018 STK_12690 024ccb915cf9fd022461a2d7350a3454 374 SUPERFAMILY SSF53335 4 371 6.1E-91 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_12690 024ccb915cf9fd022461a2d7350a3454 374 Gene3D G3DSA:3.40.50.150 1 316 4.6E-87 T 23-10-2018 STK_12690 024ccb915cf9fd022461a2d7350a3454 374 Hamap MF_00290 tRNA (guanine(26)-N(2))-dimethyltransferase [trm1]. 4 373 38.979 T 23-10-2018 IPR022923 tRNA (guanine(26)-N(2))-dimethyltransferase, archaeal and bacterial GO:0004809 MetaCyc: PWY-6829 STK_12690 024ccb915cf9fd022461a2d7350a3454 374 Pfam PF02005 N2,N2-dimethylguanosine tRNA methyltransferase 31 371 4.0E-86 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 STK_03730 ec8c96815b96abb05077dadfff24a9e0 294 Pfam PF00795 Carbon-nitrogen hydrolase 11 245 1.7E-20 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 STK_03730 ec8c96815b96abb05077dadfff24a9e0 294 SUPERFAMILY SSF56317 1 263 1.83E-31 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily STK_03730 ec8c96815b96abb05077dadfff24a9e0 294 Gene3D G3DSA:3.60.110.10 1 267 2.6E-30 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily STK_22940 ee0fa334dcbc8671a7c9bff507abad98 325 Pfam PF02754 Cysteine-rich domain 230 311 9.7E-8 T 23-10-2018 IPR004017 Cysteine-rich domain STK_22940 ee0fa334dcbc8671a7c9bff507abad98 325 Pfam PF02754 Cysteine-rich domain 126 202 2.4E-5 T 23-10-2018 IPR004017 Cysteine-rich domain STK_22940 ee0fa334dcbc8671a7c9bff507abad98 325 Gene3D G3DSA:1.10.1060.10 1 81 1.9E-10 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 STK_22940 ee0fa334dcbc8671a7c9bff507abad98 325 Pfam PF13183 4Fe-4S dicluster domain 6 66 3.0E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_22940 ee0fa334dcbc8671a7c9bff507abad98 325 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_22940 ee0fa334dcbc8671a7c9bff507abad98 325 SUPERFAMILY SSF46548 5 77 3.98E-19 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 STK_22940 ee0fa334dcbc8671a7c9bff507abad98 325 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 52 63 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_14600 3b5f8f180e472d04c7579e4d83959f3a 230 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 3 229 24.477 T 23-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 STK_14600 3b5f8f180e472d04c7579e4d83959f3a 230 Pfam PF00977 Histidine biosynthesis protein 4 223 1.4E-49 T 23-10-2018 IPR006062 Histidine biosynthesis GO:0000105 STK_14600 3b5f8f180e472d04c7579e4d83959f3a 230 Gene3D G3DSA:3.20.20.70 1 227 6.2E-51 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_14600 3b5f8f180e472d04c7579e4d83959f3a 230 SUPERFAMILY SSF51366 2 222 1.61E-39 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 STK_16240 91ef34bc766d810300a83e2008cfa9b5 372 Gene3D G3DSA:3.30.9.10 125 313 4.5E-15 T 23-10-2018 STK_16240 91ef34bc766d810300a83e2008cfa9b5 372 Gene3D G3DSA:3.50.50.60 98 351 4.5E-15 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_16240 91ef34bc766d810300a83e2008cfa9b5 372 SUPERFAMILY SSF51971 2 357 9.18E-24 T 23-10-2018 STK_16240 91ef34bc766d810300a83e2008cfa9b5 372 Gene3D G3DSA:3.50.50.60 1 79 2.5E-11 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_16240 91ef34bc766d810300a83e2008cfa9b5 372 Pfam PF01266 FAD dependent oxidoreductase 3 350 2.3E-43 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 STK_23650 9ba473318f627594f6f6e9a5a8edc79c 582 Pfam PF12222 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A 77 350 9.2E-29 T 23-10-2018 IPR021102 Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase A STK_18080 af079e4c680f725b1ee6ff204d163aa2 280 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 3 278 1.5E-125 T 23-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 STK_18080 af079e4c680f725b1ee6ff204d163aa2 280 SUPERFAMILY SSF51621 2 277 8.97E-101 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 STK_18080 af079e4c680f725b1ee6ff204d163aa2 280 ProSitePatterns PS00161 Isocitrate lyase signature. 110 115 - T 23-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 STK_18080 af079e4c680f725b1ee6ff204d163aa2 280 Pfam PF13714 Phosphoenolpyruvate phosphomutase 5 240 2.5E-57 T 23-10-2018 STK_18080 af079e4c680f725b1ee6ff204d163aa2 280 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 1 279 46.926 T 23-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 STK_18080 af079e4c680f725b1ee6ff204d163aa2 280 Gene3D G3DSA:3.20.20.60 1 280 3.9E-109 T 23-10-2018 STK_11750 42bcbbbea69afbe035d9347285c738c0 104 Gene3D G3DSA:3.30.70.20 2 104 3.0E-43 T 23-10-2018 STK_11750 42bcbbbea69afbe035d9347285c738c0 104 Pfam PF13187 4Fe-4S dicluster domain 46 99 8.9E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_11750 42bcbbbea69afbe035d9347285c738c0 104 PIRSF PIRSF000068 1 104 9.6E-45 T 23-10-2018 IPR009157 Ferredoxin zinc-binding GO:0008270|GO:0009055|GO:0051536 STK_11750 42bcbbbea69afbe035d9347285c738c0 104 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 84 95 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_11750 42bcbbbea69afbe035d9347285c738c0 104 SUPERFAMILY SSF54862 21 102 5.44E-20 T 23-10-2018 STK_21020 c8664a2cae85cfd21dd0bacce20b0822 150 PIRSF PIRSF000239 1 148 8.6E-40 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 STK_21020 c8664a2cae85cfd21dd0bacce20b0822 150 Gene3D G3DSA:3.40.30.10 3 150 2.2E-50 T 23-10-2018 STK_21020 c8664a2cae85cfd21dd0bacce20b0822 150 Pfam PF00578 AhpC/TSA family 5 126 2.7E-44 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 STK_21020 c8664a2cae85cfd21dd0bacce20b0822 150 SUPERFAMILY SSF52833 1 147 4.23E-54 T 23-10-2018 IPR036249 Thioredoxin-like superfamily STK_13400 f05f1d5ae9f7cb1cf6441ce0cbffb0bc 100 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 52 7.0E-5 T 23-10-2018 STK_13400 f05f1d5ae9f7cb1cf6441ce0cbffb0bc 100 SUPERFAMILY SSF46785 2 88 7.37E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_13400 f05f1d5ae9f7cb1cf6441ce0cbffb0bc 100 Gene3D G3DSA:1.10.10.10 2 89 5.0E-15 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_07060 e4f980f7bf9260045629504c7c8ac1af 780 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 428 605 3.3E-11 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain STK_07060 e4f980f7bf9260045629504c7c8ac1af 780 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 54 289 2.4E-14 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain STK_07060 e4f980f7bf9260045629504c7c8ac1af 780 Gene3D G3DSA:3.40.190.10 361 651 3.1E-22 T 23-10-2018 STK_07060 e4f980f7bf9260045629504c7c8ac1af 780 Gene3D G3DSA:3.40.190.10 61 341 4.5E-24 T 23-10-2018 STK_07060 e4f980f7bf9260045629504c7c8ac1af 780 SUPERFAMILY SSF53850 50 353 5.65E-31 T 23-10-2018 STK_07060 e4f980f7bf9260045629504c7c8ac1af 780 SUPERFAMILY SSF53850 377 639 3.98E-16 T 23-10-2018 STK_07060 e4f980f7bf9260045629504c7c8ac1af 780 Gene3D G3DSA:3.10.105.10 109 336 4.5E-24 T 23-10-2018 STK_01580 8e10a1a14ba103baf40ae6d98b15b159 281 SUPERFAMILY SSF103473 2 279 9.16E-13 T 23-10-2018 IPR036259 MFS transporter superfamily STK_24580 20ed3a26cd53f488996f753dbc7c3790 224 SUPERFAMILY SSF58104 36 167 3.53E-10 T 23-10-2018 STK_24580 20ed3a26cd53f488996f753dbc7c3790 224 Gene3D G3DSA:1.10.287.950 34 173 5.0E-10 T 23-10-2018 STK_00012 b395cd286632fd57c2d1aaec79b635db 96 SUPERFAMILY SSF88723 2 89 2.13E-11 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_00012 b395cd286632fd57c2d1aaec79b635db 96 Gene3D G3DSA:3.40.50.1010 1 92 3.8E-20 T 23-10-2018 STK_00012 b395cd286632fd57c2d1aaec79b635db 96 Pfam PF01850 PIN domain 2 89 2.5E-8 T 23-10-2018 IPR002716 PIN domain STK_07820 eb57e142fdcec12dec7c2b198de21c0d 131 SUPERFAMILY SSF88723 2 106 7.01E-13 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_07820 eb57e142fdcec12dec7c2b198de21c0d 131 Gene3D G3DSA:3.40.50.1010 1 116 4.5E-10 T 23-10-2018 STK_07820 eb57e142fdcec12dec7c2b198de21c0d 131 Pfam PF01850 PIN domain 1 111 3.0E-14 T 23-10-2018 IPR002716 PIN domain STK_26020 e3716ac74cc07209fa015b4a81258ab9 96 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 76 2.2E-15 T 23-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain STK_26020 e3716ac74cc07209fa015b4a81258ab9 96 Gene3D G3DSA:3.30.70.100 7 95 2.1E-17 T 23-10-2018 STK_26020 e3716ac74cc07209fa015b4a81258ab9 96 SUPERFAMILY SSF54909 2 94 9.24E-25 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel STK_07270 b59a9e421026361aa836ac511c818f3d 289 SUPERFAMILY SSF56529 49 285 1.44E-36 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 STK_07270 b59a9e421026361aa836ac511c818f3d 289 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 56 281 2.4E-35 T 23-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 STK_07270 b59a9e421026361aa836ac511c818f3d 289 Gene3D G3DSA:3.90.850.10 50 288 9.5E-36 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 STK_08610 6bd1fc3dde037a64066d1641a55cad88 379 Gene3D G3DSA:1.20.1250.20 5 379 7.6E-56 T 23-10-2018 STK_08610 6bd1fc3dde037a64066d1641a55cad88 379 Pfam PF00083 Sugar (and other) transporter 36 183 1.2E-21 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 STK_08610 6bd1fc3dde037a64066d1641a55cad88 379 SUPERFAMILY SSF103473 4 377 4.71E-53 T 23-10-2018 IPR036259 MFS transporter superfamily STK_08610 6bd1fc3dde037a64066d1641a55cad88 379 Pfam PF07690 Major Facilitator Superfamily 240 366 4.8E-11 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_07490 6803d79637d1c29a5e12a80156926772 123 SMART SM00347 17 108 0.0088 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 STK_07490 6803d79637d1c29a5e12a80156926772 123 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 20 86 1.4E-14 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal STK_07490 6803d79637d1c29a5e12a80156926772 123 SUPERFAMILY SSF46785 17 95 5.19E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_07490 6803d79637d1c29a5e12a80156926772 123 Gene3D G3DSA:1.10.10.10 11 116 1.4E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_16860 b5569b14952247e1847fa94d80622ed4 641 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 3 172 2.2E-50 T 23-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 STK_16860 b5569b14952247e1847fa94d80622ed4 641 Pfam PF01968 Hydantoinase/oxoprolinase 191 479 1.8E-99 T 23-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 STK_16860 b5569b14952247e1847fa94d80622ed4 641 SUPERFAMILY SSF53067 1 332 1.21E-7 T 23-10-2018 STK_21370 ef184e1d0ab23c2da3248433a8a5d15a 162 SUPERFAMILY SSF88723 5 118 2.47E-6 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_21370 ef184e1d0ab23c2da3248433a8a5d15a 162 SMART SM00670 5 106 4.0E-12 T 23-10-2018 IPR002716 PIN domain STK_21370 ef184e1d0ab23c2da3248433a8a5d15a 162 Pfam PF17146 PIN domain of ribonuclease 7 92 3.0E-20 T 23-10-2018 IPR033411 Ribonuclease, PIN domain Reactome: R-HSA-6791226 STK_21370 ef184e1d0ab23c2da3248433a8a5d15a 162 Gene3D G3DSA:3.40.50.1010 1 124 4.3E-31 T 23-10-2018 STK_17130 75d0acf4e08a1717d6ad7afb5832532b 163 Pfam PF01909 Nucleotidyltransferase domain 12 88 1.5E-10 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_17130 75d0acf4e08a1717d6ad7afb5832532b 163 SUPERFAMILY SSF81301 2 128 1.7E-22 T 23-10-2018 STK_17130 75d0acf4e08a1717d6ad7afb5832532b 163 Gene3D G3DSA:3.30.460.10 1 131 3.1E-32 T 23-10-2018 STK_05660 62eff44c4ae8494d29b2a22e914e5c67 388 SUPERFAMILY SSF51556 57 295 4.86E-18 T 23-10-2018 IPR032466 Metal-dependent hydrolase STK_05660 62eff44c4ae8494d29b2a22e914e5c67 388 SUPERFAMILY SSF51338 5 367 1.47E-8 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_05660 62eff44c4ae8494d29b2a22e914e5c67 388 Gene3D G3DSA:3.20.20.140 273 295 3.7E-8 T 23-10-2018 STK_05660 62eff44c4ae8494d29b2a22e914e5c67 388 Gene3D G3DSA:2.30.40.10 296 351 3.7E-8 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_05660 62eff44c4ae8494d29b2a22e914e5c67 388 Gene3D G3DSA:3.20.20.140 57 191 3.6E-12 T 23-10-2018 STK_05660 62eff44c4ae8494d29b2a22e914e5c67 388 Gene3D G3DSA:2.30.40.10 22 56 3.6E-12 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_05660 62eff44c4ae8494d29b2a22e914e5c67 388 Pfam PF01979 Amidohydrolase family 262 346 6.9E-5 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 STK_13480 dd1ce67086e7c8ff26e2745017383879 128 Pfam PF02675 S-adenosylmethionine decarboxylase 18 125 3.3E-34 T 23-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 STK_13480 dd1ce67086e7c8ff26e2745017383879 128 Hamap MF_01298 Arginine decarboxylase proenzyme. 5 127 48.385 T 23-10-2018 IPR027549 Arginine decarboxylase proenzyme GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 STK_13480 dd1ce67086e7c8ff26e2745017383879 128 Gene3D G3DSA:3.60.90.10 4 128 2.0E-37 T 23-10-2018 STK_13480 dd1ce67086e7c8ff26e2745017383879 128 SUPERFAMILY SSF56276 13 126 8.24E-35 T 23-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 STK_13480 dd1ce67086e7c8ff26e2745017383879 128 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 12 128 26.577 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 STK_13480 dd1ce67086e7c8ff26e2745017383879 128 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 14 126 4.5E-42 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 STK_23730 a9c943c2f2c107e2941792c30dfa3f70 284 Pfam PF01925 Sulfite exporter TauE/SafE 9 275 8.7E-46 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 STK_03780 dd8aed6da8e85b801ea5fd84090066fa 162 PIRSF PIRSF006533 1 162 4.7E-58 T 23-10-2018 IPR007164 Protein of unknown function DUF359 STK_03780 dd8aed6da8e85b801ea5fd84090066fa 162 Pfam PF04019 Protein of unknown function (DUF359) 42 157 4.8E-35 T 23-10-2018 IPR007164 Protein of unknown function DUF359 STK_03780 dd8aed6da8e85b801ea5fd84090066fa 162 Hamap MF_00590 UPF0218 protein . 1 160 27.827 T 23-10-2018 IPR007164 Protein of unknown function DUF359 STK_11300 5f07303ed04a6e165482f5c81cbcd0eb 433 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 386 402 2.9E-6 T 23-10-2018 STK_11300 5f07303ed04a6e165482f5c81cbcd0eb 433 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 2.9E-6 T 23-10-2018 STK_11300 5f07303ed04a6e165482f5c81cbcd0eb 433 Pfam PF13450 NAD(P)-binding Rossmann-like domain 7 51 7.0E-11 T 23-10-2018 STK_11300 5f07303ed04a6e165482f5c81cbcd0eb 433 Gene3D G3DSA:3.50.50.60 3 131 2.5E-14 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_11300 5f07303ed04a6e165482f5c81cbcd0eb 433 SUPERFAMILY SSF51905 1 415 3.94E-39 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_11300 5f07303ed04a6e165482f5c81cbcd0eb 433 Gene3D G3DSA:3.50.50.60 173 275 8.4E-12 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_18370 58944486d83dcf51d93e6deb180e46da 488 Pfam PF13187 4Fe-4S dicluster domain 357 406 2.5E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_18370 58944486d83dcf51d93e6deb180e46da 488 SUPERFAMILY SSF54862 346 434 4.39E-15 T 23-10-2018 STK_18370 58944486d83dcf51d93e6deb180e46da 488 Gene3D G3DSA:3.30.70.20 350 411 8.9E-9 T 23-10-2018 STK_25760 fbc4577d847aa04379dac4f518c4fe0b 429 Pfam PF07690 Major Facilitator Superfamily 52 373 2.3E-26 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_25760 fbc4577d847aa04379dac4f518c4fe0b 429 Gene3D G3DSA:1.20.1250.20 6 226 4.3E-33 T 23-10-2018 STK_25760 fbc4577d847aa04379dac4f518c4fe0b 429 Gene3D G3DSA:1.20.1250.20 227 422 3.6E-15 T 23-10-2018 STK_25760 fbc4577d847aa04379dac4f518c4fe0b 429 SUPERFAMILY SSF103473 7 426 4.84E-55 T 23-10-2018 IPR036259 MFS transporter superfamily STK_18820 390ce3495f2e92f8b1ba0569b6a69c60 105 SUPERFAMILY SSF88723 14 102 5.56E-5 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_18820 390ce3495f2e92f8b1ba0569b6a69c60 105 Gene3D G3DSA:3.40.50.1010 3 104 6.9E-39 T 23-10-2018 STK_12700 7cb6c4414be484695e07650664e673ef 125 SUPERFAMILY SSF46785 5 69 6.82E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_12700 7cb6c4414be484695e07650664e673ef 125 Pfam PF05158 RNA polymerase Rpc34 subunit 4 65 4.5E-6 T 23-10-2018 IPR007832 RNA polymerase Rpc34 GO:0005666|GO:0006383 Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 STK_12700 7cb6c4414be484695e07650664e673ef 125 Gene3D G3DSA:1.10.10.10 1 62 6.5E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_02650 67ef35c239f09947297d62b51ba2e535 233 Pfam PF00005 ABC transporter 19 157 3.2E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_02650 67ef35c239f09947297d62b51ba2e535 233 Gene3D G3DSA:3.40.50.300 2 231 8.1E-59 T 23-10-2018 STK_02650 67ef35c239f09947297d62b51ba2e535 233 SMART SM00382 28 230 4.0E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_02650 67ef35c239f09947297d62b51ba2e535 233 SUPERFAMILY SSF52540 4 212 7.14E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_19760 13aa098ddc5689ec151c157431d03953 477 TIGRFAM TIGR01894 cas_TM1795_cmr1: CRISPR type III-B/RAMP module RAMP protein Cmr1 10 231 3.2E-57 T 23-10-2018 IPR007522 CRISPR-associated protein TM1795 STK_19760 13aa098ddc5689ec151c157431d03953 477 Pfam PF03787 RAMP superfamily 10 305 7.4E-19 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein STK_25460 d87b507db831915c22c2cd453e80b801 371 Pfam PF01979 Amidohydrolase family 47 366 4.2E-21 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 STK_25460 d87b507db831915c22c2cd453e80b801 371 Gene3D G3DSA:3.20.20.140 50 338 3.1E-114 T 23-10-2018 STK_25460 d87b507db831915c22c2cd453e80b801 371 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 3 364 1.8E-81 T 23-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 STK_25460 d87b507db831915c22c2cd453e80b801 371 SUPERFAMILY SSF51338 1 369 4.88E-16 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_25460 d87b507db831915c22c2cd453e80b801 371 SUPERFAMILY SSF51556 51 337 3.54E-80 T 23-10-2018 IPR032466 Metal-dependent hydrolase STK_25460 d87b507db831915c22c2cd453e80b801 371 Gene3D G3DSA:2.30.40.10 10 365 3.1E-114 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_25460 d87b507db831915c22c2cd453e80b801 371 PIRSF PIRSF038994 1 371 5.0E-106 T 23-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 STK_08385 d38d27b628b04abf1c3f9e55f280cec5 73 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 45 2.8E-19 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_08385 d38d27b628b04abf1c3f9e55f280cec5 73 SUPERFAMILY SSF89447 1 46 1.59E-13 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily STK_08385 d38d27b628b04abf1c3f9e55f280cec5 73 SMART SM00966 4 49 4.3E-15 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_08385 d38d27b628b04abf1c3f9e55f280cec5 73 Gene3D G3DSA:2.10.260.10 1 42 1.2E-16 T 23-10-2018 STK_08385 d38d27b628b04abf1c3f9e55f280cec5 73 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 4 48 6.1E-15 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_16370 0a52edb481f49ca00127f8436b2d6505 153 Gene3D G3DSA:1.20.120.330 59 153 4.4E-33 T 23-10-2018 STK_16370 0a52edb481f49ca00127f8436b2d6505 153 Pfam PF05942 Archaeal PaREP1/PaREP8 family 59 153 7.6E-33 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_14405 44ac2b8c4d7c0270f22c1dfd09692347 95 Pfam PF01283 Ribosomal protein S26e 1 93 6.2E-22 T 23-10-2018 IPR000892 Ribosomal protein S26e GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_14405 44ac2b8c4d7c0270f22c1dfd09692347 95 Gene3D G3DSA:3.30.1740.20 1 93 8.5E-23 T 23-10-2018 IPR038551 Ribosomal protein S26e superfamily STK_21305 36f3648581adae6b84a5e01db24f3fdc 93 Gene3D G3DSA:3.30.110.60 7 93 4.5E-17 T 23-10-2018 IPR035920 YhbY-like superfamily STK_21305 36f3648581adae6b84a5e01db24f3fdc 93 Pfam PF01985 CRS1 / YhbY (CRM) domain 10 86 4.6E-16 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 STK_21305 36f3648581adae6b84a5e01db24f3fdc 93 SUPERFAMILY SSF75471 9 91 1.57E-16 T 23-10-2018 IPR035920 YhbY-like superfamily STK_21305 36f3648581adae6b84a5e01db24f3fdc 93 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 17 93 1.0E-35 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 STK_21305 36f3648581adae6b84a5e01db24f3fdc 93 SMART SM01103 6 88 1.4E-20 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 STK_16200 76019f9e88a7d808074b8b6f8881ab5f 212 Gene3D G3DSA:1.10.620.20 2 211 8.1E-22 T 23-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 STK_16200 76019f9e88a7d808074b8b6f8881ab5f 212 SUPERFAMILY SSF47240 2 210 1.62E-16 T 23-10-2018 IPR009078 Ferritin-like superfamily STK_13715 eef6687e2f75f7de728ccdce9d91393a 86 Pfam PF01775 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A 4 63 9.4E-11 T 23-10-2018 IPR023573 Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_13715 eef6687e2f75f7de728ccdce9d91393a 86 ProDom PD010302 RIBOSOMAL LX 50S RIBONUCLEOPROTEIN HL32 DIRECT SEQUENCING LXA LSU 7 56 3.0E-13 T 23-10-2018 IPR002768 50S ribosomal protein L18Ae, archaea GO:0003735|GO:0005840|GO:0006412 STK_13715 eef6687e2f75f7de728ccdce9d91393a 86 Hamap MF_00273 50S ribosomal protein L18Ae [rpl18a]. 4 63 16.464 T 23-10-2018 IPR028877 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_13715 eef6687e2f75f7de728ccdce9d91393a 86 SUPERFAMILY SSF160374 2 80 5.49E-20 T 23-10-2018 STK_13715 eef6687e2f75f7de728ccdce9d91393a 86 Gene3D G3DSA:3.10.20.10 4 82 3.1E-21 T 23-10-2018 STK_24490 dbd0aae4e8d1a3354767026f407667bb 266 Gene3D G3DSA:3.40.50.1580 79 263 1.1E-26 T 23-10-2018 STK_24490 dbd0aae4e8d1a3354767026f407667bb 266 SUPERFAMILY SSF53167 21 258 3.14E-36 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 STK_24490 dbd0aae4e8d1a3354767026f407667bb 266 Pfam PF01048 Phosphorylase superfamily 94 264 1.0E-23 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 STK_21050 42bfb601a5d32541622917dd7bb4c326 126 Gene3D G3DSA:1.20.1260.10 5 126 2.3E-10 T 23-10-2018 IPR012347 Ferritin-like STK_21050 42bfb601a5d32541622917dd7bb4c326 126 SUPERFAMILY SSF47240 5 123 1.15E-14 T 23-10-2018 IPR009078 Ferritin-like superfamily STK_15290 c23bcacc0ffce41d970b23a4928f811b 382 SUPERFAMILY SSF53187 4 381 1.01E-61 T 23-10-2018 STK_15290 c23bcacc0ffce41d970b23a4928f811b 382 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 65 74 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 STK_15290 c23bcacc0ffce41d970b23a4928f811b 382 SUPERFAMILY SSF55031 170 287 1.0E-14 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain STK_15290 c23bcacc0ffce41d970b23a4928f811b 382 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 5 373 1.7E-137 T 23-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase STK_15290 c23bcacc0ffce41d970b23a4928f811b 382 Gene3D G3DSA:3.40.630.10 6 369 2.4E-89 T 23-10-2018 STK_15290 c23bcacc0ffce41d970b23a4928f811b 382 Pfam PF07687 Peptidase dimerisation domain 167 286 1.9E-18 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain STK_15290 c23bcacc0ffce41d970b23a4928f811b 382 Pfam PF01546 Peptidase family M20/M25/M40 66 378 3.1E-39 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 STK_15290 c23bcacc0ffce41d970b23a4928f811b 382 Gene3D G3DSA:3.30.70.360 171 299 2.4E-89 T 23-10-2018 STK_15290 c23bcacc0ffce41d970b23a4928f811b 382 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 101 137 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 STK_13390 d111564ef3b6f23cda85300932ffb83c 109 Gene3D G3DSA:1.10.10.10 22 105 2.7E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_13390 d111564ef3b6f23cda85300932ffb83c 109 SUPERFAMILY SSF46785 29 103 6.72E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_23450 527e67e0b06d8e37490b0dde76b8abe2 370 SUPERFAMILY SSF54810 194 370 3.79E-28 T 23-10-2018 STK_23450 527e67e0b06d8e37490b0dde76b8abe2 370 Pfam PF00958 GMP synthase C terminal domain 309 369 1.2E-17 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 STK_23450 527e67e0b06d8e37490b0dde76b8abe2 370 Pfam PF02540 NAD synthase 9 191 1.9E-11 T 23-10-2018 IPR022310 NAD/GMP synthase STK_23450 527e67e0b06d8e37490b0dde76b8abe2 370 Hamap MF_00345 GMP synthase [glutamine-hydrolyzing] subunit B [guaAB]. 3 370 45.892 T 23-10-2018 IPR026598 GMP synthase subunit B KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 STK_23450 527e67e0b06d8e37490b0dde76b8abe2 370 SUPERFAMILY SSF52402 2 219 1.52E-40 T 23-10-2018 STK_23450 527e67e0b06d8e37490b0dde76b8abe2 370 Gene3D G3DSA:3.40.50.620 3 199 4.0E-58 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_23450 527e67e0b06d8e37490b0dde76b8abe2 370 Gene3D G3DSA:3.30.300.10 269 370 3.9E-19 T 23-10-2018 STK_19330 d1bf80112f14e3c757296becf9d8359b 119 Pfam PF01850 PIN domain 9 111 2.3E-6 T 23-10-2018 IPR002716 PIN domain STK_19330 d1bf80112f14e3c757296becf9d8359b 119 Gene3D G3DSA:3.40.50.1010 1 118 1.2E-11 T 23-10-2018 STK_19330 d1bf80112f14e3c757296becf9d8359b 119 SUPERFAMILY SSF88723 8 112 2.84E-11 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_13695 77e5f65ac82f3ee9e88ec79a8523f030 59 Hamap MF_00422 Protein translocase subunit SecE [secE]. 5 58 10.43 T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 STK_13695 77e5f65ac82f3ee9e88ec79a8523f030 59 TIGRFAM TIGR00327 secE_euk_arch: protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic 7 57 5.5E-11 T 23-10-2018 IPR008158 Protein translocase SEC61 complex, gamma subunit GO:0015031|GO:0015450|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 STK_13695 77e5f65ac82f3ee9e88ec79a8523f030 59 Gene3D G3DSA:1.20.5.820 1 59 2.8E-13 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 STK_13695 77e5f65ac82f3ee9e88ec79a8523f030 59 SUPERFAMILY SSF103456 5 57 2.09E-13 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 STK_12740 1aee2bc44e51f4d3700f84db68650e9b 346 Pfam PF04123 Domain of unknown function (DUF373) 3 333 9.4E-87 T 23-10-2018 IPR007254 Protein of unknown function DUF373 STK_12400 6f76c5fa140ecc147fd793876b971a24 395 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 66 362 1.6E-73 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme STK_12400 6f76c5fa140ecc147fd793876b971a24 395 Gene3D G3DSA:3.40.50.1100 52 368 1.2E-119 T 23-10-2018 STK_12400 6f76c5fa140ecc147fd793876b971a24 395 PIRSF PIRSF038945 39 391 2.7E-134 T 23-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 STK_12400 6f76c5fa140ecc147fd793876b971a24 395 SUPERFAMILY SSF53686 4 381 2.62E-108 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme STK_12400 6f76c5fa140ecc147fd793876b971a24 395 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 88 101 - T 23-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 STK_12400 6f76c5fa140ecc147fd793876b971a24 395 TIGRFAM TIGR00260 thrC: threonine synthase 50 369 2.0E-89 T 23-10-2018 IPR004450 Threonine synthase-like STK_12400 6f76c5fa140ecc147fd793876b971a24 395 Gene3D G3DSA:3.40.50.1100 96 193 1.2E-119 T 23-10-2018 STK_20660 001ebb6663cea45342bed64163488344 118 Hamap MF_00329 50S ribosomal protein L18e [rpl18e]. 5 118 27.15 T 23-10-2018 IPR022947 Ribosomal protein L18e, archaea STK_20660 001ebb6663cea45342bed64163488344 118 ProSitePatterns PS01106 Ribosomal protein L18e signature. 32 49 - T 23-10-2018 IPR021132 Ribosomal protein L18e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_20660 001ebb6663cea45342bed64163488344 118 Gene3D G3DSA:3.100.10.10 6 117 2.6E-35 T 23-10-2018 STK_20660 001ebb6663cea45342bed64163488344 118 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 53 98 4.7E-9 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P STK_20660 001ebb6663cea45342bed64163488344 118 SUPERFAMILY SSF52080 6 117 5.23E-28 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily STK_20660 001ebb6663cea45342bed64163488344 118 ProSitePatterns PS00475 Ribosomal protein L15 signature. 64 94 - T 23-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_15740 704cd104734e8bb5ebfe4f69858fb590 130 Pfam PF05168 HEPN domain 3 124 5.4E-32 T 23-10-2018 IPR007842 HEPN domain STK_15740 704cd104734e8bb5ebfe4f69858fb590 130 SUPERFAMILY SSF81593 3 125 1.77E-36 T 23-10-2018 STK_15740 704cd104734e8bb5ebfe4f69858fb590 130 SMART SM00748 7 119 6.4E-41 T 23-10-2018 IPR007842 HEPN domain STK_15740 704cd104734e8bb5ebfe4f69858fb590 130 Gene3D G3DSA:1.20.120.330 1 128 9.7E-33 T 23-10-2018 STK_13175 e100545d792c5ee1378de378543072ab 91 Gene3D G3DSA:1.10.10.10 2 90 1.3E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_13175 e100545d792c5ee1378de378543072ab 91 SUPERFAMILY SSF46785 4 87 4.82E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_13175 e100545d792c5ee1378de378543072ab 91 Pfam PF13463 Winged helix DNA-binding domain 8 73 3.6E-5 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 STK_23390 9f62f757ed45664aa91e90b99c4aa3a5 706 SMART SM01008 17 106 3.9E-32 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead STK_23390 9f62f757ed45664aa91e90b99c4aa3a5 706 Gene3D G3DSA:3.30.365.10 344 702 3.2E-102 T 23-10-2018 STK_23390 9f62f757ed45664aa91e90b99c4aa3a5 706 Gene3D G3DSA:3.30.365.10 119 332 2.3E-76 T 23-10-2018 STK_23390 9f62f757ed45664aa91e90b99c4aa3a5 706 SUPERFAMILY SSF56003 98 704 5.36E-168 T 23-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 STK_23390 9f62f757ed45664aa91e90b99c4aa3a5 706 Gene3D G3DSA:3.30.365.10 414 564 3.2E-102 T 23-10-2018 STK_23390 9f62f757ed45664aa91e90b99c4aa3a5 706 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 121 648 3.4E-149 T 23-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 STK_23390 9f62f757ed45664aa91e90b99c4aa3a5 706 SUPERFAMILY SSF54665 2 122 6.02E-33 T 23-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily STK_23390 9f62f757ed45664aa91e90b99c4aa3a5 706 Gene3D G3DSA:3.30.365.10 161 253 2.3E-76 T 23-10-2018 STK_23390 9f62f757ed45664aa91e90b99c4aa3a5 706 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 17 105 2.2E-16 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead STK_23390 9f62f757ed45664aa91e90b99c4aa3a5 706 Gene3D G3DSA:3.90.1170.50 1 106 6.5E-43 T 23-10-2018 STK_09000 de6102fa51e143fd6c0091598efdb28a 359 Gene3D G3DSA:1.20.1250.20 2 167 6.4E-15 T 23-10-2018 STK_09000 de6102fa51e143fd6c0091598efdb28a 359 Gene3D G3DSA:1.20.1250.20 184 358 1.8E-14 T 23-10-2018 STK_09000 de6102fa51e143fd6c0091598efdb28a 359 SUPERFAMILY SSF103473 6 356 1.15E-36 T 23-10-2018 IPR036259 MFS transporter superfamily STK_09000 de6102fa51e143fd6c0091598efdb28a 359 Pfam PF07690 Major Facilitator Superfamily 188 355 8.6E-15 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_09000 de6102fa51e143fd6c0091598efdb28a 359 Pfam PF07690 Major Facilitator Superfamily 9 168 1.3E-10 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_13920 1c200229810a80ef33f85191dbd62f92 323 Gene3D G3DSA:3.20.20.70 20 292 1.3E-33 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_13920 1c200229810a80ef33f85191dbd62f92 323 Pfam PF13353 4Fe-4S single cluster domain 31 123 2.1E-9 T 23-10-2018 STK_13920 1c200229810a80ef33f85191dbd62f92 323 SUPERFAMILY SSF102114 23 286 5.23E-43 T 23-10-2018 STK_13920 1c200229810a80ef33f85191dbd62f92 323 Pfam PF04055 Radical SAM superfamily 29 151 5.4E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_08170 0a036fa7a85a4eefbb6e330846fba545 443 Gene3D G3DSA:3.20.110.20 29 347 1.4E-24 T 23-10-2018 STK_08170 0a036fa7a85a4eefbb6e330846fba545 443 Pfam PF03065 Glycosyl hydrolase family 57 8 322 2.8E-80 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 STK_08170 0a036fa7a85a4eefbb6e330846fba545 443 SUPERFAMILY SSF88713 4 349 2.04E-59 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 STK_00640 7343e40a6f05f39bad9c9a8c55fccabb 468 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 267 278 - T 23-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 STK_00640 7343e40a6f05f39bad9c9a8c55fccabb 468 Gene3D G3DSA:3.40.605.10 3 458 2.8E-149 T 23-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 STK_00640 7343e40a6f05f39bad9c9a8c55fccabb 468 Gene3D G3DSA:3.40.309.10 246 435 2.8E-149 T 23-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 STK_00640 7343e40a6f05f39bad9c9a8c55fccabb 468 Pfam PF00171 Aldehyde dehydrogenase family 4 462 2.9E-149 T 23-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 STK_00640 7343e40a6f05f39bad9c9a8c55fccabb 468 SUPERFAMILY SSF53720 3 465 1.7E-138 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 STK_04275 e51c59977d33a54042362ee79be08494 82 TIGRFAM TIGR03636 uL23_arch: ribosomal protein uL23 7 82 1.2E-35 T 23-10-2018 IPR019985 Ribosomal protein L23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04275 e51c59977d33a54042362ee79be08494 82 Gene3D G3DSA:3.30.70.330 1 82 3.7E-31 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily STK_04275 e51c59977d33a54042362ee79be08494 82 ProSitePatterns PS00050 Ribosomal protein L23 signature. 60 75 - T 23-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04275 e51c59977d33a54042362ee79be08494 82 Pfam PF00276 Ribosomal protein L23 2 66 7.1E-13 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 STK_04275 e51c59977d33a54042362ee79be08494 82 SUPERFAMILY SSF54189 2 75 2.84E-22 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_04275 e51c59977d33a54042362ee79be08494 82 Hamap MF_01369_A 50S ribosomal protein L23 [rplW]. 2 82 25.058 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 STK_14550 16cc4abe3ce94fafbeb6b8840600d7a7 894 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 4 611 2.0E-53 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_14550 16cc4abe3ce94fafbeb6b8840600d7a7 894 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 3 894 7.6E-258 T 23-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 STK_14550 16cc4abe3ce94fafbeb6b8840600d7a7 894 Gene3D G3DSA:3.90.740.10 146 379 3.5E-244 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 STK_14550 16cc4abe3ce94fafbeb6b8840600d7a7 894 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 1 894 15.111 T 23-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 STK_14550 16cc4abe3ce94fafbeb6b8840600d7a7 894 Gene3D G3DSA:3.40.50.620 2 609 3.5E-244 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_14550 16cc4abe3ce94fafbeb6b8840600d7a7 894 SUPERFAMILY SSF50677 159 372 5.86E-37 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 STK_14550 16cc4abe3ce94fafbeb6b8840600d7a7 894 SUPERFAMILY SSF47323 622 832 2.43E-26 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 STK_14550 16cc4abe3ce94fafbeb6b8840600d7a7 894 SUPERFAMILY SSF52374 2 617 1.89E-83 T 23-10-2018 STK_14550 16cc4abe3ce94fafbeb6b8840600d7a7 894 Gene3D G3DSA:1.10.10.720 784 836 2.0E-13 T 23-10-2018 STK_14550 16cc4abe3ce94fafbeb6b8840600d7a7 894 Gene3D G3DSA:1.10.730.10 612 728 1.1E-17 T 23-10-2018 STK_14550 16cc4abe3ce94fafbeb6b8840600d7a7 894 Pfam PF08264 Anticodon-binding domain of tRNA 645 799 1.6E-20 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 STK_14550 16cc4abe3ce94fafbeb6b8840600d7a7 894 Gene3D G3DSA:3.30.2320.20 755 894 2.0E-13 T 23-10-2018 STK_09890 bce61f3da1645676a2a1ca5ee48ead38 264 SUPERFAMILY SSF102114 27 218 4.22E-7 T 23-10-2018 STK_09890 bce61f3da1645676a2a1ca5ee48ead38 264 Pfam PF04055 Radical SAM superfamily 28 198 1.4E-10 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_09890 bce61f3da1645676a2a1ca5ee48ead38 264 Gene3D G3DSA:3.80.30.30 63 256 3.7E-7 T 23-10-2018 STK_05170 fac3969cb1ac1f3cceb0ac960f819646 98 Pfam PF04242 Protein of unknown function (DUF424) 11 98 1.5E-24 T 23-10-2018 IPR007355 Protein of unknown function DUF424 STK_05170 fac3969cb1ac1f3cceb0ac960f819646 98 Gene3D G3DSA:3.30.1860.10 1 98 1.6E-23 T 23-10-2018 STK_15330 8326df7f87f4b6e38331c9da169d1202 297 SUPERFAMILY SSF52518 11 295 1.06E-75 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold STK_15330 8326df7f87f4b6e38331c9da169d1202 297 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 65 202 2.3E-18 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 STK_15330 8326df7f87f4b6e38331c9da169d1202 297 Gene3D G3DSA:3.40.50.970 88 297 3.7E-72 T 23-10-2018 STK_00018 81489a8df340b8a6495a72b406b2d63f 50 SUPERFAMILY SSF81593 9 45 3.22E-5 T 23-10-2018 STK_00018 81489a8df340b8a6495a72b406b2d63f 50 Pfam PF05168 HEPN domain 6 44 8.6E-6 T 23-10-2018 IPR007842 HEPN domain STK_22860 4dbb6d41ae44bec7899f5b4210975b60 628 PIRSF PIRSF006402 1 627 1.9E-163 T 23-10-2018 IPR024705 Spermatogenesis-associated protein 20 STK_22860 4dbb6d41ae44bec7899f5b4210975b60 628 Pfam PF03190 Protein of unknown function, DUF255 4 159 2.1E-66 T 23-10-2018 IPR004879 Domain of unknown function DUF255 STK_22860 4dbb6d41ae44bec7899f5b4210975b60 628 Gene3D G3DSA:3.40.30.10 2 169 3.6E-66 T 23-10-2018 STK_22860 4dbb6d41ae44bec7899f5b4210975b60 628 SUPERFAMILY SSF52833 4 130 4.84E-35 T 23-10-2018 IPR036249 Thioredoxin-like superfamily STK_22860 4dbb6d41ae44bec7899f5b4210975b60 628 SUPERFAMILY SSF48208 187 486 5.35E-36 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 STK_09740 775c8c3fa2bbd63cbb307adf3f60e895 437 Pfam PF00534 Glycosyl transferases group 1 239 404 1.8E-35 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 STK_09740 775c8c3fa2bbd63cbb307adf3f60e895 437 Gene3D G3DSA:3.40.50.2000 38 229 3.3E-6 T 23-10-2018 STK_09740 775c8c3fa2bbd63cbb307adf3f60e895 437 Gene3D G3DSA:3.40.50.2000 230 414 1.9E-42 T 23-10-2018 STK_09740 775c8c3fa2bbd63cbb307adf3f60e895 437 SUPERFAMILY SSF53756 43 426 6.63E-62 T 23-10-2018 STK_20960 e2604066f0221f888ff1321c4ff92781 140 Gene3D G3DSA:3.40.50.280 1 139 3.3E-61 T 23-10-2018 STK_20960 e2604066f0221f888ff1321c4ff92781 140 SUPERFAMILY SSF52242 4 131 2.35E-51 T 23-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 STK_20960 e2604066f0221f888ff1321c4ff92781 140 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 4 133 1.4E-55 T 23-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 STK_20960 e2604066f0221f888ff1321c4ff92781 140 Pfam PF02310 B12 binding domain 6 116 1.5E-23 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 STK_10960 12bac41ffaa1271ea8293748332162a5 136 SUPERFAMILY SSF143422 2 128 6.41E-50 T 23-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 STK_10960 12bac41ffaa1271ea8293748332162a5 136 Pfam PF01797 Transposase IS200 like 11 128 3.9E-43 T 23-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 STK_10960 12bac41ffaa1271ea8293748332162a5 136 SMART SM01321 10 128 6.5E-48 T 23-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 STK_10960 12bac41ffaa1271ea8293748332162a5 136 Gene3D G3DSA:3.30.70.1290 1 136 5.2E-53 T 23-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 STK_19560 e491da08acb74d88f5bdbd56ace5af42 504 Gene3D G3DSA:3.30.420.350 56 275 4.3E-54 T 23-10-2018 STK_19560 e491da08acb74d88f5bdbd56ace5af42 504 Gene3D G3DSA:3.90.870.20 299 502 3.9E-68 T 23-10-2018 IPR038152 Carbamoyltransferase, C-terminal domain superfamily STK_19560 e491da08acb74d88f5bdbd56ace5af42 504 SUPERFAMILY SSF53067 55 287 3.88E-8 T 23-10-2018 STK_19560 e491da08acb74d88f5bdbd56ace5af42 504 Pfam PF02543 Carbamoyltransferase N-terminus 28 281 1.6E-38 T 23-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 STK_19560 e491da08acb74d88f5bdbd56ace5af42 504 Pfam PF16861 Carbamoyltransferase C-terminus 334 503 1.0E-57 T 23-10-2018 IPR031730 Carbamoyltransferase, C-terminal STK_24730 48a856bed1930ebc6b449e520475adcf 287 SUPERFAMILY SSF52540 3 223 3.39E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_24730 48a856bed1930ebc6b449e520475adcf 287 Gene3D G3DSA:3.40.50.300 1 235 5.1E-53 T 23-10-2018 STK_24730 48a856bed1930ebc6b449e520475adcf 287 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 STK_24730 48a856bed1930ebc6b449e520475adcf 287 SMART SM00382 28 230 1.5E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_24730 48a856bed1930ebc6b449e520475adcf 287 Pfam PF00005 ABC transporter 19 155 2.2E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_20430 0382584ed99802c56c7bb6af5852a375 235 SUPERFAMILY SSF54631 6 166 5.68E-15 T 23-10-2018 STK_20430 0382584ed99802c56c7bb6af5852a375 235 SUPERFAMILY SSF54631 122 229 1.2E-17 T 23-10-2018 STK_20430 0382584ed99802c56c7bb6af5852a375 235 SMART SM00116 124 170 0.2 T 23-10-2018 IPR000644 CBS domain STK_20430 0382584ed99802c56c7bb6af5852a375 235 SMART SM00116 184 230 0.018 T 23-10-2018 IPR000644 CBS domain STK_20430 0382584ed99802c56c7bb6af5852a375 235 SMART SM00116 7 54 0.068 T 23-10-2018 IPR000644 CBS domain STK_20430 0382584ed99802c56c7bb6af5852a375 235 Gene3D G3DSA:3.10.580.10 120 230 1.1E-17 T 23-10-2018 STK_20430 0382584ed99802c56c7bb6af5852a375 235 Gene3D G3DSA:3.10.580.10 2 110 9.1E-9 T 23-10-2018 STK_20430 0382584ed99802c56c7bb6af5852a375 235 Pfam PF00571 CBS domain 121 166 5.1E-6 T 23-10-2018 IPR000644 CBS domain STK_20430 0382584ed99802c56c7bb6af5852a375 235 Pfam PF00571 CBS domain 6 50 3.0E-7 T 23-10-2018 IPR000644 CBS domain STK_20430 0382584ed99802c56c7bb6af5852a375 235 Pfam PF00571 CBS domain 180 228 2.6E-4 T 23-10-2018 IPR000644 CBS domain STK_05460 5ab490f306e98a9e7ee9da6135e564a2 324 Gene3D G3DSA:3.50.50.60 127 249 4.4E-119 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_05460 5ab490f306e98a9e7ee9da6135e564a2 324 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 145 165 - T 23-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 STK_05460 5ab490f306e98a9e7ee9da6135e564a2 324 Gene3D G3DSA:3.50.50.60 17 313 4.4E-119 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_05460 5ab490f306e98a9e7ee9da6135e564a2 324 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 18 317 2.7E-109 T 23-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 STK_05460 5ab490f306e98a9e7ee9da6135e564a2 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 115 133 3.1E-34 T 23-10-2018 STK_05460 5ab490f306e98a9e7ee9da6135e564a2 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 241 257 3.1E-34 T 23-10-2018 STK_05460 5ab490f306e98a9e7ee9da6135e564a2 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 290 3.1E-34 T 23-10-2018 STK_05460 5ab490f306e98a9e7ee9da6135e564a2 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 3.1E-34 T 23-10-2018 STK_05460 5ab490f306e98a9e7ee9da6135e564a2 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 19 38 3.1E-34 T 23-10-2018 STK_05460 5ab490f306e98a9e7ee9da6135e564a2 324 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 17 306 3.0E-54 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 STK_05460 5ab490f306e98a9e7ee9da6135e564a2 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 138 150 8.0E-55 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_05460 5ab490f306e98a9e7ee9da6135e564a2 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 243 264 8.0E-55 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_05460 5ab490f306e98a9e7ee9da6135e564a2 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 116 124 8.0E-55 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_05460 5ab490f306e98a9e7ee9da6135e564a2 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 205 221 8.0E-55 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_05460 5ab490f306e98a9e7ee9da6135e564a2 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 50 65 8.0E-55 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_05460 5ab490f306e98a9e7ee9da6135e564a2 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 153 177 8.0E-55 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_05460 5ab490f306e98a9e7ee9da6135e564a2 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 18 40 8.0E-55 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_05460 5ab490f306e98a9e7ee9da6135e564a2 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 298 317 8.0E-55 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 STK_05460 5ab490f306e98a9e7ee9da6135e564a2 324 SUPERFAMILY SSF51905 16 319 4.16E-50 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_01510 94a9f34d04e2eaf970aebd896b506356 318 Gene3D G3DSA:2.60.120.580 131 224 4.1E-32 T 23-10-2018 STK_01510 94a9f34d04e2eaf970aebd896b506356 318 Gene3D G3DSA:2.60.120.580 2 116 9.7E-22 T 23-10-2018 STK_01510 94a9f34d04e2eaf970aebd896b506356 318 SUPERFAMILY SSF141130 3 312 4.18E-88 T 23-10-2018 STK_01510 94a9f34d04e2eaf970aebd896b506356 318 Gene3D G3DSA:3.10.28.20 239 313 1.5E-8 T 23-10-2018 STK_01510 94a9f34d04e2eaf970aebd896b506356 318 Pfam PF03069 Acetamidase/Formamidase family 8 149 1.2E-25 T 23-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 STK_01510 94a9f34d04e2eaf970aebd896b506356 318 Pfam PF03069 Acetamidase/Formamidase family 157 312 3.5E-45 T 23-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 STK_14890 5da7718106429022247d1a321501f8dd 214 Pfam PF02676 Methyltransferase TYW3 16 185 2.1E-28 T 23-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 STK_14890 5da7718106429022247d1a321501f8dd 214 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 5 187 29.498 T 23-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 STK_14890 5da7718106429022247d1a321501f8dd 214 Gene3D G3DSA:3.30.1960.10 1 185 1.2E-54 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 STK_14890 5da7718106429022247d1a321501f8dd 214 SUPERFAMILY SSF111278 3 184 3.53E-52 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 STK_17980 d3c46692bf5b10fc438d83f1703ff8ba 165 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 39 71 3.8E-9 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal STK_17980 d3c46692bf5b10fc438d83f1703ff8ba 165 SUPERFAMILY SSF50249 11 153 6.51E-29 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_17980 d3c46692bf5b10fc438d83f1703ff8ba 165 Gene3D G3DSA:1.10.12.20 7 77 1.2E-26 T 23-10-2018 STK_07660 13818f6cc81d35fcb41a2cafef9cdb6e 109 Gene3D G3DSA:1.10.10.10 2 103 5.8E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_07660 13818f6cc81d35fcb41a2cafef9cdb6e 109 SUPERFAMILY SSF46785 7 96 2.64E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_07660 13818f6cc81d35fcb41a2cafef9cdb6e 109 Pfam PF14947 Winged helix-turn-helix 6 84 4.7E-19 T 23-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain STK_04590 322abf493bac351bf19b68b7d917e0b0 103 Hamap MF_00369 50S ribosomal protein L21e [rpl21e]. 3 98 27.75 T 23-10-2018 IPR022856 Ribosomal protein L21e, archaeal STK_04590 322abf493bac351bf19b68b7d917e0b0 103 ProSitePatterns PS01171 Ribosomal protein L21e signature. 39 64 - T 23-10-2018 IPR018259 Ribosomal protein L21e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04590 322abf493bac351bf19b68b7d917e0b0 103 SUPERFAMILY SSF50104 4 97 5.41E-33 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily STK_04590 322abf493bac351bf19b68b7d917e0b0 103 Gene3D G3DSA:2.30.30.70 2 98 6.3E-36 T 23-10-2018 IPR036948 Ribosomal protein L21 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04590 322abf493bac351bf19b68b7d917e0b0 103 Pfam PF01157 Ribosomal protein L21e 4 95 4.4E-35 T 23-10-2018 IPR001147 Ribosomal protein L21e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_01890 f2961dc34053ca0ba0985b410d6ed087 262 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 207 224 - T 23-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 STK_01890 f2961dc34053ca0ba0985b410d6ed087 262 Gene3D G3DSA:3.40.1180.10 14 262 1.7E-83 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 STK_01890 f2961dc34053ca0ba0985b410d6ed087 262 SUPERFAMILY SSF64005 27 256 6.15E-74 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 STK_01890 f2961dc34053ca0ba0985b410d6ed087 262 Pfam PF01255 Putative undecaprenyl diphosphate synthase 38 261 4.0E-66 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 STK_01890 f2961dc34053ca0ba0985b410d6ed087 262 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 31 262 36.091 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 STK_01890 f2961dc34053ca0ba0985b410d6ed087 262 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 32 261 3.4E-67 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 STK_20270 bc84039e0393f7b11b8c1b2b725c383c 521 Pfam PF00999 Sodium/hydrogen exchanger family 10 355 1.0E-22 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 STK_20270 bc84039e0393f7b11b8c1b2b725c383c 521 Gene3D G3DSA:1.20.1530.20 2 361 1.9E-33 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily STK_07180 339e1551aa4862e97cab9e73012639f3 109 Gene3D G3DSA:2.102.10.10 1 109 1.4E-20 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 STK_07180 339e1551aa4862e97cab9e73012639f3 109 Pfam PF00355 Rieske [2Fe-2S] domain 3 95 3.7E-14 T 23-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 STK_07180 339e1551aa4862e97cab9e73012639f3 109 SUPERFAMILY SSF50022 1 107 6.68E-21 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 STK_05625 ed6f77154c1c6c3a53a2ec0c5a8e619e 47 Gene3D G3DSA:1.10.620.20 3 47 7.5E-10 T 23-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 STK_05625 ed6f77154c1c6c3a53a2ec0c5a8e619e 47 SUPERFAMILY SSF47240 5 45 5.95E-10 T 23-10-2018 IPR009078 Ferritin-like superfamily STK_05625 ed6f77154c1c6c3a53a2ec0c5a8e619e 47 Pfam PF04945 YHS domain 3 46 5.7E-19 T 23-10-2018 IPR007029 YHS domain STK_05625 ed6f77154c1c6c3a53a2ec0c5a8e619e 47 SMART SM00746 5 42 4.8E-11 T 23-10-2018 IPR011017 TRASH domain STK_06760 d6468f7bc362d97f94414324c0132cfa 522 SUPERFAMILY SSF81442 21 490 2.49E-91 T 23-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_06760 d6468f7bc362d97f94414324c0132cfa 522 PRINTS PR01165 Cytochrome c oxidase subunit I signature 240 261 1.5E-6 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_06760 d6468f7bc362d97f94414324c0132cfa 522 PRINTS PR01165 Cytochrome c oxidase subunit I signature 424 445 1.5E-6 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_06760 d6468f7bc362d97f94414324c0132cfa 522 PRINTS PR01165 Cytochrome c oxidase subunit I signature 62 85 1.5E-6 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_06760 d6468f7bc362d97f94414324c0132cfa 522 PRINTS PR01165 Cytochrome c oxidase subunit I signature 373 392 1.5E-6 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_06760 d6468f7bc362d97f94414324c0132cfa 522 PRINTS PR01165 Cytochrome c oxidase subunit I signature 137 149 1.5E-6 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_06760 d6468f7bc362d97f94414324c0132cfa 522 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 21 468 1.2E-71 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_06760 d6468f7bc362d97f94414324c0132cfa 522 Gene3D G3DSA:1.20.210.10 14 519 5.9E-83 T 23-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_13500 055c68d0d1d5176f2fcf65e487f086ca 363 SUPERFAMILY SSF53901 54 332 1.73E-17 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_13500 055c68d0d1d5176f2fcf65e487f086ca 363 PIRSF PIRSF000429 1 347 1.8E-20 T 23-10-2018 IPR002155 Thiolase GO:0016747 STK_13500 055c68d0d1d5176f2fcf65e487f086ca 363 Gene3D G3DSA:3.40.47.10 1 361 7.2E-57 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_00320 29c79d496c03609b58692ffd1b2d13aa 555 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 34 386 9.1E-49 T 23-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core STK_00320 29c79d496c03609b58692ffd1b2d13aa 555 SMART SM00487 1 213 0.0064 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain STK_00320 29c79d496c03609b58692ffd1b2d13aa 555 Gene3D G3DSA:3.40.50.300 15 207 4.1E-13 T 23-10-2018 STK_00320 29c79d496c03609b58692ffd1b2d13aa 555 Gene3D G3DSA:3.40.50.300 239 388 1.4E-12 T 23-10-2018 STK_00320 29c79d496c03609b58692ffd1b2d13aa 555 Pfam PF00270 DEAD/DEAH box helicase 33 191 1.6E-7 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 STK_00320 29c79d496c03609b58692ffd1b2d13aa 555 Pfam PF00271 Helicase conserved C-terminal domain 259 354 3.8E-7 T 23-10-2018 IPR001650 Helicase, C-terminal STK_00320 29c79d496c03609b58692ffd1b2d13aa 555 SUPERFAMILY SSF52540 33 368 1.26E-30 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_02180 00e5a5209237eeb17ed217505756ddf3 211 SUPERFAMILY SSF69618 1 205 1.11E-26 T 23-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 STK_02180 00e5a5209237eeb17ed217505756ddf3 211 Pfam PF02602 Uroporphyrinogen-III synthase HemD 35 200 1.9E-17 T 23-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 STK_02180 00e5a5209237eeb17ed217505756ddf3 211 Gene3D G3DSA:3.40.50.10090 13 103 1.3E-14 T 23-10-2018 STK_02180 00e5a5209237eeb17ed217505756ddf3 211 Gene3D G3DSA:3.40.50.10090 115 207 5.1E-8 T 23-10-2018 STK_03960 559a769531a9cd6723bd5615f6eb1fe8 369 Pfam PF01979 Amidohydrolase family 51 321 9.1E-14 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 STK_03960 559a769531a9cd6723bd5615f6eb1fe8 369 SUPERFAMILY SSF51556 55 328 3.14E-31 T 23-10-2018 IPR032466 Metal-dependent hydrolase STK_03960 559a769531a9cd6723bd5615f6eb1fe8 369 Gene3D G3DSA:3.20.20.140 56 321 1.5E-24 T 23-10-2018 STK_09020 4c19eed3b6eb680fcea2d8dcce7ba4eb 232 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 STK_09020 4c19eed3b6eb680fcea2d8dcce7ba4eb 232 Gene3D G3DSA:3.40.50.300 4 232 4.1E-68 T 23-10-2018 STK_09020 4c19eed3b6eb680fcea2d8dcce7ba4eb 232 SMART SM00382 35 224 1.1E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_09020 4c19eed3b6eb680fcea2d8dcce7ba4eb 232 Pfam PF00005 ABC transporter 26 176 4.1E-35 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_09020 4c19eed3b6eb680fcea2d8dcce7ba4eb 232 SUPERFAMILY SSF52540 6 226 1.03E-68 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_17745 8263c7f4f44fb144a1af119a0ca14ed4 93 PIRSF PIRSF036548 1 93 2.0E-23 T 23-10-2018 IPR012206 Ferredoxin-like, FixX GO:0005506 STK_17745 8263c7f4f44fb144a1af119a0ca14ed4 93 Gene3D G3DSA:3.30.70.20 6 87 1.1E-19 T 23-10-2018 STK_17745 8263c7f4f44fb144a1af119a0ca14ed4 93 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 62 73 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_17745 8263c7f4f44fb144a1af119a0ca14ed4 93 SUPERFAMILY SSF54862 26 89 4.51E-19 T 23-10-2018 STK_17745 8263c7f4f44fb144a1af119a0ca14ed4 93 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 12 87 1.3E-13 T 23-10-2018 STK_08390 d89fbc527054dc32a042a44f48f16b8e 133 SUPERFAMILY SSF88723 4 132 8.13E-24 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_08390 d89fbc527054dc32a042a44f48f16b8e 133 SMART SM00670 2 122 1.9E-9 T 23-10-2018 IPR002716 PIN domain STK_08390 d89fbc527054dc32a042a44f48f16b8e 133 Gene3D G3DSA:3.40.50.1010 1 133 9.2E-18 T 23-10-2018 STK_08390 d89fbc527054dc32a042a44f48f16b8e 133 Pfam PF01850 PIN domain 5 126 9.9E-18 T 23-10-2018 IPR002716 PIN domain STK_16040 4f58dbcf27bbd88b8bbefd7e9a1b3791 174 Pfam PF13412 Winged helix-turn-helix DNA-binding 13 52 3.0E-6 T 23-10-2018 STK_16040 4f58dbcf27bbd88b8bbefd7e9a1b3791 174 SUPERFAMILY SSF46785 7 78 1.08E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_16040 4f58dbcf27bbd88b8bbefd7e9a1b3791 174 Gene3D G3DSA:1.10.10.10 3 76 2.3E-13 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_22120 fb8e816c09750fd7cf180e83200aa190 235 Pfam PF13938 Putative heavy-metal chelation 8 85 1.0E-11 T 23-10-2018 IPR025251 Domain of unknown function DUF4213 STK_22120 fb8e816c09750fd7cf180e83200aa190 235 SUPERFAMILY SSF159713 1 231 1.18E-40 T 23-10-2018 STK_22120 fb8e816c09750fd7cf180e83200aa190 235 Pfam PF04016 Putative heavy-metal chelation 96 232 3.0E-30 T 23-10-2018 IPR007161 Putative heavy-metal chelation domain STK_14980 245b839a00ca10a8c19f53659bdba9e6 477 SUPERFAMILY SSF56059 109 335 2.08E-33 T 23-10-2018 STK_14980 245b839a00ca10a8c19f53659bdba9e6 477 Gene3D G3DSA:3.90.600.10 347 453 2.1E-6 T 23-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 STK_14980 245b839a00ca10a8c19f53659bdba9e6 477 SUPERFAMILY SSF52440 1 107 4.6E-22 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily STK_14980 245b839a00ca10a8c19f53659bdba9e6 477 Gene3D G3DSA:3.30.1490.20 127 202 9.7E-9 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 STK_14980 245b839a00ca10a8c19f53659bdba9e6 477 Gene3D G3DSA:3.40.50.20 2 100 8.1E-20 T 23-10-2018 STK_14980 245b839a00ca10a8c19f53659bdba9e6 477 SMART SM01209 108 312 4.8E-63 T 23-10-2018 STK_14980 245b839a00ca10a8c19f53659bdba9e6 477 Gene3D G3DSA:3.30.470.20 203 344 7.1E-36 T 23-10-2018 STK_14980 245b839a00ca10a8c19f53659bdba9e6 477 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 107 1.4E-22 T 23-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 STK_14980 245b839a00ca10a8c19f53659bdba9e6 477 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 439 4.7E-99 T 23-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 STK_14980 245b839a00ca10a8c19f53659bdba9e6 477 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 109 312 3.1E-41 T 23-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 STK_14980 245b839a00ca10a8c19f53659bdba9e6 477 SUPERFAMILY SSF51246 346 440 2.67E-9 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 STK_14980 245b839a00ca10a8c19f53659bdba9e6 477 SMART SM01210 346 441 8.1E-9 T 23-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 STK_14980 245b839a00ca10a8c19f53659bdba9e6 477 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 348 439 9.1E-7 T 23-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 STK_20490 e075e417c315b9b1e2b0e8207df8c53e 411 Gene3D G3DSA:3.20.20.140 57 340 3.4E-89 T 23-10-2018 STK_20490 e075e417c315b9b1e2b0e8207df8c53e 411 SUPERFAMILY SSF51556 56 339 1.13E-71 T 23-10-2018 IPR032466 Metal-dependent hydrolase STK_20490 e075e417c315b9b1e2b0e8207df8c53e 411 SUPERFAMILY SSF51338 8 392 3.73E-18 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_20490 e075e417c315b9b1e2b0e8207df8c53e 411 Pfam PF01979 Amidohydrolase family 53 385 1.7E-48 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 STK_20490 e075e417c315b9b1e2b0e8207df8c53e 411 Gene3D G3DSA:2.30.40.10 27 386 3.4E-89 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 STK_01860 2c016494d253ba3f4eb2d5be5cfb094b 355 SUPERFAMILY SSF53756 18 352 1.26E-32 T 23-10-2018 STK_01860 2c016494d253ba3f4eb2d5be5cfb094b 355 Gene3D G3DSA:3.40.50.2000 172 332 1.0E-25 T 23-10-2018 STK_01860 2c016494d253ba3f4eb2d5be5cfb094b 355 Pfam PF00534 Glycosyl transferases group 1 180 310 1.4E-17 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 STK_20460 2110eb5e4d382ad006525ae8ee396fe1 197 Gene3D G3DSA:3.90.550.10 2 181 6.2E-27 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_20460 2110eb5e4d382ad006525ae8ee396fe1 197 SUPERFAMILY SSF53448 7 128 1.62E-17 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_20460 2110eb5e4d382ad006525ae8ee396fe1 197 Pfam PF12804 MobA-like NTP transferase domain 9 123 2.1E-16 T 23-10-2018 IPR025877 MobA-like NTP transferase STK_04237 3170d0e7e6671ddf66f8a5a4e83f8588 88 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 9 75 13.076 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04237 3170d0e7e6671ddf66f8a5a4e83f8588 88 Gene3D G3DSA:1.10.287.310 8 78 1.0E-13 T 23-10-2018 STK_04237 3170d0e7e6671ddf66f8a5a4e83f8588 88 SUPERFAMILY SSF46561 25 73 3.4E-11 T 23-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04237 3170d0e7e6671ddf66f8a5a4e83f8588 88 Pfam PF00831 Ribosomal L29 protein 26 72 9.6E-13 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04237 3170d0e7e6671ddf66f8a5a4e83f8588 88 TIGRFAM TIGR00012 L29: ribosomal protein uL29 25 73 2.0E-14 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04237 3170d0e7e6671ddf66f8a5a4e83f8588 88 ProSitePatterns PS00579 Ribosomal protein L29 signature. 54 68 - T 23-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_03705 af24271b9338e3c60b549ef7f29c3f9e 49 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 41 2.4E-10 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 STK_03705 af24271b9338e3c60b549ef7f29c3f9e 49 SUPERFAMILY SSF47598 1 47 2.78E-13 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 STK_03705 af24271b9338e3c60b549ef7f29c3f9e 49 Gene3D G3DSA:1.10.1220.10 8 45 1.3E-9 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 STK_03625 4c58f2f3fd66dea657b18f905907b94d 63 Pfam PF01599 Ribosomal protein S27a 14 56 7.6E-14 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 STK_03625 4c58f2f3fd66dea657b18f905907b94d 63 Gene3D G3DSA:2.20.25.660 1 61 1.9E-9 T 23-10-2018 IPR038582 S27a-like superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 STK_03625 4c58f2f3fd66dea657b18f905907b94d 63 SMART SM01402 13 56 3.2E-19 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 STK_03625 4c58f2f3fd66dea657b18f905907b94d 63 SUPERFAMILY SSF57829 13 61 3.48E-14 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 STK_03625 4c58f2f3fd66dea657b18f905907b94d 63 Hamap MF_00777 30S ribosomal protein S27ae [rps27ae]. 13 59 16.969 T 23-10-2018 IPR022845 Ribosomal protein S27ae STK_17720 0e29195a2dfa51553b46361d476a3d53 334 Pfam PF13732 Domain of unknown function (DUF4162) 219 308 5.5E-15 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 STK_17720 0e29195a2dfa51553b46361d476a3d53 334 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 13 309 2.9E-130 T 23-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 STK_17720 0e29195a2dfa51553b46361d476a3d53 334 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 STK_17720 0e29195a2dfa51553b46361d476a3d53 334 Pfam PF00005 ABC transporter 22 164 7.2E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_17720 0e29195a2dfa51553b46361d476a3d53 334 SMART SM00382 30 222 1.2E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_17720 0e29195a2dfa51553b46361d476a3d53 334 Gene3D G3DSA:3.40.50.300 2 238 9.6E-71 T 23-10-2018 STK_17720 0e29195a2dfa51553b46361d476a3d53 334 SUPERFAMILY SSF52540 4 228 1.09E-68 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_08910 8f047b1219919011ab90a74e55d563bf 170 SUPERFAMILY SSF103473 3 155 1.16E-15 T 23-10-2018 IPR036259 MFS transporter superfamily STK_08910 8f047b1219919011ab90a74e55d563bf 170 Gene3D G3DSA:1.20.1250.20 2 164 7.7E-11 T 23-10-2018 STK_00200 246002db1d5f2ce7b871df6f8106fd61 361 TIGRFAM TIGR01765 tspaseT_teng_N: transposase, putative, N-terminal domain 19 87 7.3E-24 T 23-10-2018 IPR010094 Transposase (putative), N-terminal STK_13630 dc283002d782e7234e7a120e1db857fe 209 Pfam PF04256 Protein of unknown function (DUF434) 8 63 1.6E-24 T 23-10-2018 IPR007368 Protein of unknown function DUF434 STK_13630 dc283002d782e7234e7a120e1db857fe 209 ProDom PD019177 PF1672 MJ0935 ST1363 PH1730 UNCHARACTERIZED ARCHAEAL 9 60 3.0E-23 T 23-10-2018 IPR007368 Protein of unknown function DUF434 STK_10170 0c94d0cb9a9a443bf3feeb1a8c6ac6f4 531 PIRSF PIRSF006060 2 524 6.0E-26 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_10170 0c94d0cb9a9a443bf3feeb1a8c6ac6f4 531 Gene3D G3DSA:1.20.1740.10 15 517 1.6E-14 T 23-10-2018 STK_10170 0c94d0cb9a9a443bf3feeb1a8c6ac6f4 531 Pfam PF13520 Amino acid permease 37 485 4.9E-13 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_23340 16484bd6427d51e9dd5d6ce7ec10a7d4 311 Gene3D G3DSA:3.40.50.720 108 277 9.7E-64 T 23-10-2018 STK_23340 16484bd6427d51e9dd5d6ce7ec10a7d4 311 Gene3D G3DSA:3.30.1780.10 16 291 9.7E-64 T 23-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 STK_23340 16484bd6427d51e9dd5d6ce7ec10a7d4 311 SUPERFAMILY SSF51735 2 304 1.39E-67 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_23340 16484bd6427d51e9dd5d6ce7ec10a7d4 311 PIRSF PIRSF001439 70 305 4.4E-54 T 23-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 STK_23340 16484bd6427d51e9dd5d6ce7ec10a7d4 311 PIRSF PIRSF001439 1 64 4.5 T 23-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 STK_23340 16484bd6427d51e9dd5d6ce7ec10a7d4 311 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 74 295 1.3E-47 T 23-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 STK_25250 4da49e57b237b92ff7d89f36e708b9b6 641 Gene3D G3DSA:3.20.20.80 150 508 8.9E-135 T 23-10-2018 STK_25250 4da49e57b237b92ff7d89f36e708b9b6 641 SUPERFAMILY SSF51011 507 581 1.58E-16 T 23-10-2018 STK_25250 4da49e57b237b92ff7d89f36e708b9b6 641 Gene3D G3DSA:2.60.40.1180 509 582 5.1E-24 T 23-10-2018 IPR013780 Glycosyl hydrolase, all-beta STK_25250 4da49e57b237b92ff7d89f36e708b9b6 641 Pfam PF01055 Glycosyl hydrolases family 31 143 586 1.8E-128 T 23-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 STK_25250 4da49e57b237b92ff7d89f36e708b9b6 641 Gene3D G3DSA:2.60.40.1760 1 148 4.3E-32 T 23-10-2018 STK_25250 4da49e57b237b92ff7d89f36e708b9b6 641 SUPERFAMILY SSF51445 152 505 2.11E-79 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily STK_25250 4da49e57b237b92ff7d89f36e708b9b6 641 ProSitePatterns PS00129 Glycosyl hydrolases family 31 active site. 309 316 - T 23-10-2018 IPR030458 Glycosyl hydrolases family 31, active site STK_25250 4da49e57b237b92ff7d89f36e708b9b6 641 SUPERFAMILY SSF74650 40 150 3.01E-24 T 23-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 STK_25250 4da49e57b237b92ff7d89f36e708b9b6 641 Pfam PF13802 Galactose mutarotase-like 56 122 1.9E-19 T 23-10-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain STK_03340 8d78e87aea921a7e44ae1e0d772bf09a 178 SUPERFAMILY SSF46785 6 89 1.24E-22 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_03340 8d78e87aea921a7e44ae1e0d772bf09a 178 SMART SM00531 19 158 7.7E-29 T 23-10-2018 IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal GO:0006367 Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 STK_03340 8d78e87aea921a7e44ae1e0d772bf09a 178 Hamap MF_01909 Transcription factor E [tfe]. 3 166 26.218 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 STK_03340 8d78e87aea921a7e44ae1e0d772bf09a 178 Gene3D G3DSA:1.10.10.10 3 89 4.4E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_03340 8d78e87aea921a7e44ae1e0d772bf09a 178 Pfam PF02002 TFIIE alpha subunit 8 111 1.2E-18 T 23-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 STK_03340 8d78e87aea921a7e44ae1e0d772bf09a 178 PIRSF PIRSF006373 1 177 3.4E-66 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 STK_01575 dffd7242d9cb1ac12799c576af1e9eba 75 SUPERFAMILY SSF103473 8 74 3.53E-6 T 23-10-2018 IPR036259 MFS transporter superfamily STK_05090 f04df1d528ecf3bb67c964d7634528dc 335 PIRSF PIRSF029122 1 329 8.9E-142 T 23-10-2018 IPR010581 Protein of unknown function DUF1152 STK_05090 f04df1d528ecf3bb67c964d7634528dc 335 Pfam PF06626 Protein of unknown function (DUF1152) 4 301 4.5E-114 T 23-10-2018 IPR010581 Protein of unknown function DUF1152 STK_02087 8ccf3ac8ef3d9bd46fe59855c3ccc8a6 91 PIRSF PIRSF006521 1 89 7.1E-34 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 STK_02087 8ccf3ac8ef3d9bd46fe59855c3ccc8a6 91 Pfam PF00736 EF-1 guanine nucleotide exchange domain 6 89 7.7E-18 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 STK_02087 8ccf3ac8ef3d9bd46fe59855c3ccc8a6 91 SMART SM00888 3 89 1.4E-39 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 STK_02087 8ccf3ac8ef3d9bd46fe59855c3ccc8a6 91 Gene3D G3DSA:3.30.70.60 1 89 4.0E-28 T 23-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 STK_02087 8ccf3ac8ef3d9bd46fe59855c3ccc8a6 91 Hamap MF_00043 Elongation factor 1-beta [ef1b]. 1 91 42.41 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 STK_02087 8ccf3ac8ef3d9bd46fe59855c3ccc8a6 91 TIGRFAM TIGR00489 aEF-1_beta: translation elongation factor aEF-1 beta 1 89 2.0E-21 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 STK_02087 8ccf3ac8ef3d9bd46fe59855c3ccc8a6 91 SUPERFAMILY SSF54984 1 89 1.44E-24 T 23-10-2018 IPR036219 Translation elongation factor eEF-1beta-like superfamily Reactome: R-HSA-156842 STK_17660 2857f1c891015cfcbc75fa38abe2141f 338 Pfam PF01145 SPFH domain / Band 7 family 40 215 1.5E-19 T 23-10-2018 IPR001107 Band 7 domain STK_17660 2857f1c891015cfcbc75fa38abe2141f 338 SUPERFAMILY SSF117892 86 210 2.48E-8 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily STK_17660 2857f1c891015cfcbc75fa38abe2141f 338 Gene3D G3DSA:3.30.479.30 95 206 4.4E-5 T 23-10-2018 STK_14190 8202b225db63acb99333c9a26c78a75e 297 Pfam PF00557 Metallopeptidase family M24 7 289 2.4E-42 T 23-10-2018 IPR000994 Peptidase M24 STK_14190 8202b225db63acb99333c9a26c78a75e 297 SUPERFAMILY SSF55920 3 297 3.27E-68 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like STK_14190 8202b225db63acb99333c9a26c78a75e 297 TIGRFAM TIGR00501 met_pdase_II: methionine aminopeptidase, type II 7 297 2.5E-96 T 23-10-2018 IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800|Reactome: R-HSA-2514859 STK_14190 8202b225db63acb99333c9a26c78a75e 297 SUPERFAMILY SSF46785 197 273 8.34E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_14190 8202b225db63acb99333c9a26c78a75e 297 Gene3D G3DSA:3.90.230.10 11 288 8.0E-95 T 23-10-2018 STK_14190 8202b225db63acb99333c9a26c78a75e 297 ProSitePatterns PS01202 Methionine aminopeptidase subfamily 2 signature. 80 96 - T 23-10-2018 IPR018349 Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site MetaCyc: PWY-7799|MetaCyc: PWY-7800 STK_14190 8202b225db63acb99333c9a26c78a75e 297 Hamap MF_01975 Methionine aminopeptidase [map]. 6 297 46.005 T 23-10-2018 IPR028595 Methionine aminopeptidase, archaeal GO:0004177|GO:0006508 MetaCyc: PWY-7799|MetaCyc: PWY-7800 STK_14190 8202b225db63acb99333c9a26c78a75e 297 PRINTS PR00599 Methionine aminopeptidase-1 signature 147 159 2.6E-13 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 STK_14190 8202b225db63acb99333c9a26c78a75e 297 PRINTS PR00599 Methionine aminopeptidase-1 signature 80 96 2.6E-13 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 STK_14190 8202b225db63acb99333c9a26c78a75e 297 PRINTS PR00599 Methionine aminopeptidase-1 signature 55 68 2.6E-13 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 STK_14190 8202b225db63acb99333c9a26c78a75e 297 PRINTS PR00599 Methionine aminopeptidase-1 signature 178 190 2.6E-13 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 STK_14190 8202b225db63acb99333c9a26c78a75e 297 Gene3D G3DSA:1.10.10.10 197 274 8.0E-95 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_03790 fc9b5e2a42385868694df54b135b670c 183 SUPERFAMILY SSF50249 82 178 9.7E-22 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_03790 fc9b5e2a42385868694df54b135b670c 183 Gene3D G3DSA:2.40.50.140 82 183 4.4E-26 T 23-10-2018 STK_03790 fc9b5e2a42385868694df54b135b670c 183 SMART SM00316 80 164 4.9E-15 T 23-10-2018 IPR022967 RNA-binding domain, S1 STK_03790 fc9b5e2a42385868694df54b135b670c 183 SUPERFAMILY SSF88798 1 77 1.96E-21 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 STK_03790 fc9b5e2a42385868694df54b135b670c 183 TIGRFAM TIGR00448 rpoE: DNA-directed RNA polymerase 1 177 1.9E-55 T 23-10-2018 IPR004519 DNA-directed RNA polymerase, subunit E/RPC8 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 STK_03790 fc9b5e2a42385868694df54b135b670c 183 Pfam PF03876 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 10 77 6.5E-18 T 23-10-2018 IPR005576 RNA polymerase Rpb7, N-terminal GO:0003899|GO:0006351 STK_03790 fc9b5e2a42385868694df54b135b670c 183 Gene3D G3DSA:3.30.1490.120 1 81 6.3E-29 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 STK_03790 fc9b5e2a42385868694df54b135b670c 183 Pfam PF00575 S1 RNA binding domain 81 147 7.2E-15 T 23-10-2018 IPR003029 S1 domain GO:0003676 STK_09065 bf6905a14d8204a677240f7107a98995 95 SUPERFAMILY SSF89447 20 76 1.62E-11 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily STK_09065 bf6905a14d8204a677240f7107a98995 95 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 21 60 6.0E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_09065 bf6905a14d8204a677240f7107a98995 95 Gene3D G3DSA:2.10.260.10 19 56 3.3E-13 T 23-10-2018 STK_09065 bf6905a14d8204a677240f7107a98995 95 SMART SM00966 18 63 1.4E-9 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_09065 bf6905a14d8204a677240f7107a98995 95 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 21 58 2.9E-13 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_18880 5069540c97c22f618dbea2d6e9075a08 344 Pfam PF03099 Biotin/lipoate A/B protein ligase family 51 161 6.0E-9 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 STK_18880 5069540c97c22f618dbea2d6e9075a08 344 SUPERFAMILY SSF82649 259 339 2.62E-10 T 23-10-2018 STK_18880 5069540c97c22f618dbea2d6e9075a08 344 SUPERFAMILY SSF55681 6 247 4.76E-55 T 23-10-2018 STK_18880 5069540c97c22f618dbea2d6e9075a08 344 Gene3D G3DSA:3.30.390.50 256 340 7.7E-21 T 23-10-2018 STK_18880 5069540c97c22f618dbea2d6e9075a08 344 Gene3D G3DSA:3.30.930.10 11 252 9.8E-52 T 23-10-2018 STK_05550 c0be1450bf47f0a5c806e5c17eb644c1 170 Pfam PF00011 Hsp20/alpha crystallin family 85 169 2.1E-11 T 23-10-2018 IPR002068 Alpha crystallin/Hsp20 domain STK_05550 c0be1450bf47f0a5c806e5c17eb644c1 170 Gene3D G3DSA:2.60.40.790 74 160 1.6E-23 T 23-10-2018 IPR008978 HSP20-like chaperone STK_05550 c0be1450bf47f0a5c806e5c17eb644c1 170 SUPERFAMILY SSF49764 77 168 5.1E-22 T 23-10-2018 IPR008978 HSP20-like chaperone STK_08590 aa9aa5ff48de739dae5e27d94fd64746 432 PIRSF PIRSF006060 1 429 3.8E-34 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_08590 aa9aa5ff48de739dae5e27d94fd64746 432 Pfam PF00324 Amino acid permease 20 397 3.7E-19 T 23-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 STK_08590 aa9aa5ff48de739dae5e27d94fd64746 432 Gene3D G3DSA:1.20.1740.10 8 430 8.2E-22 T 23-10-2018 STK_12745 8a3449e18cf3f32e8d62ce529be7bafa 71 Gene3D G3DSA:2.30.30.860 2 71 6.5E-19 T 23-10-2018 STK_24100 16781d2c95ad23d34277d6bee6f6df37 531 Gene3D G3DSA:3.40.50.970 2 184 1.3E-47 T 23-10-2018 STK_24100 16781d2c95ad23d34277d6bee6f6df37 531 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 173 2.4E-44 T 23-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 STK_24100 16781d2c95ad23d34277d6bee6f6df37 531 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 389 525 2.8E-15 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 STK_24100 16781d2c95ad23d34277d6bee6f6df37 531 SUPERFAMILY SSF52518 3 180 1.46E-35 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold STK_24100 16781d2c95ad23d34277d6bee6f6df37 531 Gene3D G3DSA:3.40.50.970 345 531 8.8E-28 T 23-10-2018 STK_24100 16781d2c95ad23d34277d6bee6f6df37 531 Gene3D G3DSA:3.40.50.1220 187 344 2.9E-10 T 23-10-2018 STK_24100 16781d2c95ad23d34277d6bee6f6df37 531 SUPERFAMILY SSF52518 353 530 2.32E-25 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold STK_24100 16781d2c95ad23d34277d6bee6f6df37 531 SUPERFAMILY SSF52467 189 367 8.63E-12 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily STK_21790 de6d8ca3a90eddb033c38b2bd16c78fb 305 Gene3D G3DSA:3.30.1780.10 4 302 2.4E-69 T 23-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 STK_21790 de6d8ca3a90eddb033c38b2bd16c78fb 305 PIRSF PIRSF001439 1 305 4.3E-54 T 23-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 STK_21790 de6d8ca3a90eddb033c38b2bd16c78fb 305 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 3 299 1.1E-41 T 23-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 STK_21790 de6d8ca3a90eddb033c38b2bd16c78fb 305 SUPERFAMILY SSF51735 1 304 4.36E-68 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_21790 de6d8ca3a90eddb033c38b2bd16c78fb 305 Gene3D G3DSA:3.40.50.720 120 280 2.4E-69 T 23-10-2018 STK_01770 2bfa5bf701bc2980011e49f7ef19adce 184 SUPERFAMILY SSF144091 4 179 6.54E-27 T 23-10-2018 STK_01770 2bfa5bf701bc2980011e49f7ef19adce 184 Gene3D G3DSA:1.20.1540.10 1 183 1.2E-23 T 23-10-2018 IPR035952 Rhomboid-like superfamily STK_01770 2bfa5bf701bc2980011e49f7ef19adce 184 Pfam PF01694 Rhomboid family 41 177 3.1E-19 T 23-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 STK_20790 8a6d78f23d412dd64b35dc33a512c358 336 Gene3D G3DSA:3.20.20.70 25 258 2.8E-12 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_20790 8a6d78f23d412dd64b35dc33a512c358 336 SUPERFAMILY SSF102114 27 202 1.14E-21 T 23-10-2018 STK_20790 8a6d78f23d412dd64b35dc33a512c358 336 Pfam PF13394 4Fe-4S single cluster domain 31 120 9.2E-6 T 23-10-2018 STK_20790 8a6d78f23d412dd64b35dc33a512c358 336 Pfam PF04055 Radical SAM superfamily 32 137 1.3E-7 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_00770 f3fa33d1c5cfbd9e02459d555d87ec9f 536 Gene3D G3DSA:3.30.300.310 431 536 2.7E-26 T 23-10-2018 STK_00770 f3fa33d1c5cfbd9e02459d555d87ec9f 536 Pfam PF00501 AMP-binding enzyme 19 435 1.4E-87 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 STK_00770 f3fa33d1c5cfbd9e02459d555d87ec9f 536 Pfam PF13193 AMP-binding enzyme C-terminal domain 445 522 1.9E-15 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain STK_00770 f3fa33d1c5cfbd9e02459d555d87ec9f 536 Gene3D G3DSA:3.40.50.12780 2 430 6.0E-102 T 23-10-2018 STK_00770 f3fa33d1c5cfbd9e02459d555d87ec9f 536 SUPERFAMILY SSF56801 8 532 1.44E-125 T 23-10-2018 STK_00770 f3fa33d1c5cfbd9e02459d555d87ec9f 536 ProSitePatterns PS00455 Putative AMP-binding domain signature. 175 186 - T 23-10-2018 IPR020845 AMP-binding, conserved site STK_03980 846ed0e8f91fbe7af36a9b42bf2160c0 115 Pfam PF12136 RNA polymerase Rpo13 subunit HTH domain 33 72 2.8E-18 T 23-10-2018 IPR021985 RNA polymerase Rpo13 subunit HTH domain STK_22730 4d4cc6d18eb5999bdc046b92b57bc8fb 260 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 13 93 1.8E-24 T 23-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 STK_22730 4d4cc6d18eb5999bdc046b92b57bc8fb 260 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 8 256 26.377 T 23-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 STK_22730 4d4cc6d18eb5999bdc046b92b57bc8fb 260 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 111 186 1.1E-6 T 23-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase STK_22730 4d4cc6d18eb5999bdc046b92b57bc8fb 260 SUPERFAMILY SSF51735 117 253 1.4E-30 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_22730 4d4cc6d18eb5999bdc046b92b57bc8fb 260 SUPERFAMILY SSF53223 3 99 8.06E-23 T 23-10-2018 STK_22730 4d4cc6d18eb5999bdc046b92b57bc8fb 260 Gene3D G3DSA:3.40.50.10860 12 243 5.4E-61 T 23-10-2018 STK_22730 4d4cc6d18eb5999bdc046b92b57bc8fb 260 Gene3D G3DSA:3.40.50.720 101 223 5.4E-61 T 23-10-2018 STK_04420 731275b8f9b43f55fa031d49a6f2f813 275 Gene3D G3DSA:3.30.230.70 13 275 7.3E-84 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 STK_04420 731275b8f9b43f55fa031d49a6f2f813 275 Pfam PF01138 3' exoribonuclease family, domain 1 37 171 4.6E-31 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 STK_04420 731275b8f9b43f55fa031d49a6f2f813 275 SUPERFAMILY SSF54211 10 219 1.16E-57 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold STK_04420 731275b8f9b43f55fa031d49a6f2f813 275 SUPERFAMILY SSF55666 192 273 7.85E-18 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 STK_04420 731275b8f9b43f55fa031d49a6f2f813 275 Pfam PF03725 3' exoribonuclease family, domain 2 196 253 1.6E-9 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 STK_04420 731275b8f9b43f55fa031d49a6f2f813 275 Hamap MF_00622 Exosome complex component Rrp42 [rrp42]. 7 272 44.612 T 23-10-2018 IPR020869 Exosome complex component Rrp42, archaea GO:0000178|GO:0006401 STK_23400 eb37531d29187c1d236d4aa750d7ed56 170 Pfam PF01435 Peptidase family M48 34 168 5.0E-15 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 STK_23400 eb37531d29187c1d236d4aa750d7ed56 170 Gene3D G3DSA:3.30.2010.10 19 88 1.9E-6 T 23-10-2018 STK_10480 eef7b4b814bc8cf0022ca9517857d010 136 SUPERFAMILY SSF143422 2 128 6.28E-49 T 23-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 STK_10480 eef7b4b814bc8cf0022ca9517857d010 136 Pfam PF01797 Transposase IS200 like 11 128 3.0E-42 T 23-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 STK_10480 eef7b4b814bc8cf0022ca9517857d010 136 Gene3D G3DSA:3.30.70.1290 1 136 2.0E-52 T 23-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 STK_10480 eef7b4b814bc8cf0022ca9517857d010 136 SMART SM01321 10 128 1.3E-46 T 23-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 STK_05050 7f4570500ab1697d1253f58729ec5ad2 306 Hamap MF_00384 Homoserine kinase [thrB]. 3 304 27.255 T 23-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 STK_05050 7f4570500ab1697d1253f58729ec5ad2 306 PRINTS PR00958 Homoserine kinase signature 8 23 1.5E-25 T 23-10-2018 STK_05050 7f4570500ab1697d1253f58729ec5ad2 306 PRINTS PR00958 Homoserine kinase signature 170 187 1.5E-25 T 23-10-2018 STK_05050 7f4570500ab1697d1253f58729ec5ad2 306 PRINTS PR00958 Homoserine kinase signature 90 105 1.5E-25 T 23-10-2018 STK_05050 7f4570500ab1697d1253f58729ec5ad2 306 PRINTS PR00958 Homoserine kinase signature 130 143 1.5E-25 T 23-10-2018 STK_05050 7f4570500ab1697d1253f58729ec5ad2 306 PRINTS PR00958 Homoserine kinase signature 249 264 1.5E-25 T 23-10-2018 STK_05050 7f4570500ab1697d1253f58729ec5ad2 306 SUPERFAMILY SSF54211 1 153 1.59E-29 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold STK_05050 7f4570500ab1697d1253f58729ec5ad2 306 TIGRFAM TIGR00191 thrB: homoserine kinase 3 300 6.4E-63 T 23-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 STK_05050 7f4570500ab1697d1253f58729ec5ad2 306 Pfam PF08544 GHMP kinases C terminal 210 275 5.5E-7 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain STK_05050 7f4570500ab1697d1253f58729ec5ad2 306 Gene3D G3DSA:3.30.70.890 160 289 1.6E-26 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily STK_05050 7f4570500ab1697d1253f58729ec5ad2 306 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 83 94 - T 23-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 STK_05050 7f4570500ab1697d1253f58729ec5ad2 306 Gene3D G3DSA:3.30.230.10 1 159 1.7E-41 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup STK_05050 7f4570500ab1697d1253f58729ec5ad2 306 Pfam PF00288 GHMP kinases N terminal domain 77 143 3.7E-13 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 STK_05050 7f4570500ab1697d1253f58729ec5ad2 306 PIRSF PIRSF000676 1 306 2.3E-81 T 23-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 STK_05050 7f4570500ab1697d1253f58729ec5ad2 306 SUPERFAMILY SSF55060 163 283 1.38E-23 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily STK_25090 1d5adb449f71f98b51afc656c470e2d4 234 Pfam PF00005 ABC transporter 19 157 2.0E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_25090 1d5adb449f71f98b51afc656c470e2d4 234 SMART SM00382 28 202 4.1E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_25090 1d5adb449f71f98b51afc656c470e2d4 234 Gene3D G3DSA:3.40.50.300 1 229 1.7E-58 T 23-10-2018 STK_25090 1d5adb449f71f98b51afc656c470e2d4 234 SUPERFAMILY SSF52540 3 213 5.74E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_19750 b6e0e5a6049688c88bcd120ccf93c811 163 SUPERFAMILY SSF158568 17 162 2.35E-17 T 23-10-2018 IPR023101 AF1862-like domain superfamily STK_19750 b6e0e5a6049688c88bcd120ccf93c811 163 Pfam PF09701 CRISPR-associated protein (Cas_Cmr5) 16 159 2.0E-4 T 23-10-2018 IPR010160 CRISPR-associated protein, Cmr5 STK_19750 b6e0e5a6049688c88bcd120ccf93c811 163 TIGRFAM TIGR01881 cas_Cmr5: CRISPR type III-B/RAMP module-associated protein Cmr5 1 163 6.3E-49 T 23-10-2018 IPR010160 CRISPR-associated protein, Cmr5 STK_09860 bee3aa5b79f4af45c78b12028ca0fc03 141 Pfam PF01909 Nucleotidyltransferase domain 11 76 4.9E-9 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_09860 bee3aa5b79f4af45c78b12028ca0fc03 141 SUPERFAMILY SSF81301 6 74 1.66E-11 T 23-10-2018 STK_09860 bee3aa5b79f4af45c78b12028ca0fc03 141 Gene3D G3DSA:3.30.460.10 2 87 5.6E-12 T 23-10-2018 STK_09990 1ca4dd5a9b2bed4d5a2fad8f102a3ca5 125 Gene3D G3DSA:2.60.120.10 1 112 3.1E-29 T 23-10-2018 IPR014710 RmlC-like jelly roll fold STK_09990 1ca4dd5a9b2bed4d5a2fad8f102a3ca5 125 SUPERFAMILY SSF51182 13 121 1.21E-27 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily STK_09990 1ca4dd5a9b2bed4d5a2fad8f102a3ca5 125 Pfam PF07883 Cupin domain 42 108 1.8E-16 T 23-10-2018 IPR013096 Cupin 2, conserved barrel STK_04760 ba48ea807f227d65c2da6059612a8b89 149 SUPERFAMILY SSF49777 1 148 1.27E-46 T 23-10-2018 IPR036610 PEBP-like superfamily STK_04760 ba48ea807f227d65c2da6059612a8b89 149 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 18 144 2.1E-39 T 23-10-2018 IPR005247 YbhB/YbcL STK_04760 ba48ea807f227d65c2da6059612a8b89 149 Gene3D G3DSA:3.90.280.10 1 149 3.0E-52 T 23-10-2018 IPR036610 PEBP-like superfamily STK_04760 ba48ea807f227d65c2da6059612a8b89 149 Pfam PF01161 Phosphatidylethanolamine-binding protein 14 146 1.9E-35 T 23-10-2018 IPR008914 Phosphatidylethanolamine-binding protein STK_21390 c1bb81e851be3757df3a3b0d22426680 565 ProSitePatterns PS00455 Putative AMP-binding domain signature. 205 216 - T 23-10-2018 IPR020845 AMP-binding, conserved site STK_21390 c1bb81e851be3757df3a3b0d22426680 565 Gene3D G3DSA:3.40.50.12780 40 447 1.8E-73 T 23-10-2018 STK_21390 c1bb81e851be3757df3a3b0d22426680 565 Pfam PF13193 AMP-binding enzyme C-terminal domain 460 531 1.8E-17 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain STK_21390 c1bb81e851be3757df3a3b0d22426680 565 Gene3D G3DSA:3.30.300.30 448 565 1.8E-23 T 23-10-2018 STK_21390 c1bb81e851be3757df3a3b0d22426680 565 SUPERFAMILY SSF56801 2 560 4.32E-125 T 23-10-2018 STK_21390 c1bb81e851be3757df3a3b0d22426680 565 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 3 55 2.7E-14 T 23-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 STK_21390 c1bb81e851be3757df3a3b0d22426680 565 Pfam PF00501 AMP-binding enzyme 59 451 5.2E-71 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 STK_16250 2289201dd48b29017c233e5d6855299c 173 Gene3D G3DSA:1.25.40.350 2 173 6.9E-91 T 23-10-2018 STK_16250 2289201dd48b29017c233e5d6855299c 173 SUPERFAMILY SSF101424 7 167 1.44E-72 T 23-10-2018 IPR036321 Hypothetical protein ST1625 STK_16250 2289201dd48b29017c233e5d6855299c 173 Pfam PF09205 Domain of unknown function (DUF1955) 7 166 6.1E-72 T 23-10-2018 IPR015288 Protein of unknown function DUF1955 STK_11610 605267e1bbe606fd9df6174b29b57197 202 SUPERFAMILY SSF46785 138 193 9.9E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_11610 605267e1bbe606fd9df6174b29b57197 202 Gene3D G3DSA:1.10.10.10 135 201 1.2E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_11610 605267e1bbe606fd9df6174b29b57197 202 TIGRFAM TIGR01884 cas_HTH: CRISPR locus-related DNA-binding protein 3 194 2.1E-29 T 23-10-2018 IPR010163 CRISPR locus-related putative DNA-binding protein Csa3 STK_11610 605267e1bbe606fd9df6174b29b57197 202 Gene3D G3DSA:3.40.50.11700 2 134 9.7E-11 T 23-10-2018 STK_11610 605267e1bbe606fd9df6174b29b57197 202 Pfam PF13412 Winged helix-turn-helix DNA-binding 150 183 2.0E-6 T 23-10-2018 STK_17440 12bdbf69a829a82b4b617fba3a8eb95f 484 Pfam PF04434 SWIM zinc finger 50 80 4.2E-5 T 23-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 STK_08720 24360690334986dc1e3dff23c421ce45 199 Gene3D G3DSA:3.40.50.360 1 199 1.2E-68 T 23-10-2018 IPR029039 Flavoprotein-like superfamily STK_08720 24360690334986dc1e3dff23c421ce45 199 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 7 193 5.1E-45 T 23-10-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 STK_08720 24360690334986dc1e3dff23c421ce45 199 Pfam PF03358 NADPH-dependent FMN reductase 19 144 3.3E-15 T 23-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 STK_08720 24360690334986dc1e3dff23c421ce45 199 SUPERFAMILY SSF52218 6 194 4.77E-49 T 23-10-2018 IPR029039 Flavoprotein-like superfamily STK_21100 90ece5a813226a54a1fdc593f5ecd4ed 266 Pfam PF01545 Cation efflux family 3 185 4.0E-9 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 STK_21100 90ece5a813226a54a1fdc593f5ecd4ed 266 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 5 263 5.8E-26 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 STK_21100 90ece5a813226a54a1fdc593f5ecd4ed 266 SUPERFAMILY SSF161111 5 186 7.19E-11 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily STK_21100 90ece5a813226a54a1fdc593f5ecd4ed 266 SUPERFAMILY SSF160240 205 262 9.55E-11 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 STK_21100 90ece5a813226a54a1fdc593f5ecd4ed 266 Gene3D G3DSA:1.20.1510.10 2 183 2.0E-6 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily STK_23370 ac249007e273331492ed736bbae0d3ac 227 Gene3D G3DSA:3.90.550.10 3 220 3.1E-42 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_23370 ac249007e273331492ed736bbae0d3ac 227 SUPERFAMILY SSF53448 4 221 7.97E-37 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_23370 ac249007e273331492ed736bbae0d3ac 227 Pfam PF00535 Glycosyl transferase family 2 4 161 2.7E-26 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 STK_06440 e135007a2a5087691d61e55b89bf8ba1 374 SUPERFAMILY SSF103473 5 367 3.4E-45 T 23-10-2018 IPR036259 MFS transporter superfamily STK_06440 e135007a2a5087691d61e55b89bf8ba1 374 Gene3D G3DSA:1.20.1250.20 3 373 5.0E-41 T 23-10-2018 STK_06440 e135007a2a5087691d61e55b89bf8ba1 374 Pfam PF07690 Major Facilitator Superfamily 16 328 7.1E-31 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_17320 4af588560918cb7601ccbbf5483ff749 286 Pfam PF03537 Glycoside-hydrolase family GH114 61 217 5.7E-10 T 23-10-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain STK_17320 4af588560918cb7601ccbbf5483ff749 286 SUPERFAMILY SSF51445 43 277 7.07E-26 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily STK_17320 4af588560918cb7601ccbbf5483ff749 286 Gene3D G3DSA:3.20.20.70 45 282 2.2E-14 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_13460 85c0d5dbf61969403e42edc5382b3e44 413 Pfam PF00589 Phage integrase family 234 378 3.4E-10 T 23-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 STK_13460 85c0d5dbf61969403e42edc5382b3e44 413 SUPERFAMILY SSF56349 131 404 1.59E-20 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 STK_07457 6ecaa765195b456624c81faabcf2200a 99 Gene3D G3DSA:3.30.460.10 2 92 3.3E-14 T 23-10-2018 STK_07457 6ecaa765195b456624c81faabcf2200a 99 Pfam PF01909 Nucleotidyltransferase domain 5 75 3.7E-9 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_07457 6ecaa765195b456624c81faabcf2200a 99 SUPERFAMILY SSF81301 5 92 3.02E-15 T 23-10-2018 STK_20857 df66565646a88223e25e22fc0bd2235a 50 Gene3D G3DSA:1.10.10.10 1 46 8.4E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_04960 d148649d159c0455a53e39d5f932be35 262 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 7 236 1.0E-44 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA STK_04960 d148649d159c0455a53e39d5f932be35 262 SUPERFAMILY SSF56784 3 261 7.86E-65 T 23-10-2018 IPR036412 HAD-like superfamily STK_04960 d148649d159c0455a53e39d5f932be35 262 Pfam PF13344 Haloacid dehalogenase-like hydrolase 7 106 3.1E-24 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA STK_04960 d148649d159c0455a53e39d5f932be35 262 Gene3D G3DSA:3.40.50.1000 8 257 7.3E-72 T 23-10-2018 IPR023214 HAD superfamily STK_04960 d148649d159c0455a53e39d5f932be35 262 Pfam PF13242 HAD-hyrolase-like 186 259 1.4E-16 T 23-10-2018 STK_04960 d148649d159c0455a53e39d5f932be35 262 PIRSF PIRSF000915 1 262 6.4E-57 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA STK_04960 d148649d159c0455a53e39d5f932be35 262 Gene3D G3DSA:3.40.50.1000 84 186 7.3E-72 T 23-10-2018 IPR023214 HAD superfamily STK_16560 a4b747cf8ea62aba4d92d6aa081c543a 281 Pfam PF06157 Protein of unknown function (DUF973) 6 280 1.1E-79 T 23-10-2018 IPR009321 Protein of unknown function DUF973 STK_01970 07f0e92b9307faca2b9b3831835da972 604 Gene3D G3DSA:3.40.50.300 220 355 8.5E-6 T 23-10-2018 STK_01970 07f0e92b9307faca2b9b3831835da972 604 Pfam PF12846 AAA-like domain 457 584 2.2E-10 T 23-10-2018 STK_01970 07f0e92b9307faca2b9b3831835da972 604 SUPERFAMILY SSF52540 247 594 2.38E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_01970 07f0e92b9307faca2b9b3831835da972 604 Gene3D G3DSA:3.40.50.300 418 599 1.1E-21 T 23-10-2018 STK_17030 f0b03fb361630877bfb64da210b5a206 185 Pfam PF07185 Protein of unknown function (DUF1404) 13 180 2.8E-59 T 23-10-2018 IPR009844 Protein of unknown function DUF1404 STK_02150 7d2bb87c252601f111a284bb2e39e518 419 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 228 264 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 STK_02150 7d2bb87c252601f111a284bb2e39e518 419 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 1 419 88.372 T 23-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 STK_02150 7d2bb87c252601f111a284bb2e39e518 419 Gene3D G3DSA:3.90.1150.10 6 411 2.0E-159 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 STK_02150 7d2bb87c252601f111a284bb2e39e518 419 Gene3D G3DSA:3.40.640.10 65 311 2.0E-159 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 STK_02150 7d2bb87c252601f111a284bb2e39e518 419 Pfam PF00202 Aminotransferase class-III 26 394 2.2E-73 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 STK_02150 7d2bb87c252601f111a284bb2e39e518 419 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 2 418 4.3E-171 T 23-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 STK_02150 7d2bb87c252601f111a284bb2e39e518 419 SUPERFAMILY SSF53383 2 418 1.36E-116 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase STK_04195 2c5768de5749f2c496586b695261ed5b 54 SUPERFAMILY SSF57716 8 52 9.41E-5 T 23-10-2018 STK_04195 2c5768de5749f2c496586b695261ed5b 54 Pfam PF00253 Ribosomal protein S14p/S29e 7 53 6.3E-12 T 23-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_04195 2c5768de5749f2c496586b695261ed5b 54 ProSitePatterns PS00527 Ribosomal protein S14 signature. 20 42 - T 23-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04195 2c5768de5749f2c496586b695261ed5b 54 Hamap MF_01364_A 30S ribosomal protein S14 type Z [rpsZ]. 2 54 17.362 T 23-10-2018 IPR023676 Ribosomal protein S14, type Z, archaeal GO:0003723|GO:0003735|GO:0006412|GO:0015935 STK_04195 2c5768de5749f2c496586b695261ed5b 54 Gene3D G3DSA:4.10.830.10 6 54 4.5E-21 T 23-10-2018 STK_09220 29e2199141c06a5feedc6c0fda2922b6 362 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 43 350 6.3E-106 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 STK_09220 29e2199141c06a5feedc6c0fda2922b6 362 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 14 360 36.179 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 STK_09220 29e2199141c06a5feedc6c0fda2922b6 362 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 17 349 1.7E-110 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 STK_09220 29e2199141c06a5feedc6c0fda2922b6 362 Gene3D G3DSA:3.40.50.10470 162 361 4.5E-59 T 23-10-2018 STK_09220 29e2199141c06a5feedc6c0fda2922b6 362 Gene3D G3DSA:1.20.120.420 10 161 1.7E-41 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 STK_09220 29e2199141c06a5feedc6c0fda2922b6 362 SUPERFAMILY SSF100950 13 352 2.68E-109 T 23-10-2018 IPR037171 NagB/RpiA transferase-like STK_09220 29e2199141c06a5feedc6c0fda2922b6 362 Pfam PF01008 Initiation factor 2 subunit family 56 350 1.3E-76 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 STK_22900 0a106c1d4ba0bf2c1ec1d07c527279a4 252 Hamap MF_00722 Endonuclease NucS [nucS]. 25 237 35.014 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 STK_22900 0a106c1d4ba0bf2c1ec1d07c527279a4 252 Pfam PF01939 Endonuclease NucS 25 231 3.7E-58 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 STK_22900 0a106c1d4ba0bf2c1ec1d07c527279a4 252 Gene3D G3DSA:2.70.180.20 2 120 1.5E-34 T 23-10-2018 STK_22900 0a106c1d4ba0bf2c1ec1d07c527279a4 252 Gene3D G3DSA:3.40.1350.10 121 230 9.3E-31 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 STK_05740 5323214e72c80864346a6d664c3a4712 285 PRINTS PR00990 Ribokinase signature 7 28 1.0E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 STK_05740 5323214e72c80864346a6d664c3a4712 285 PRINTS PR00990 Ribokinase signature 190 201 1.0E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 STK_05740 5323214e72c80864346a6d664c3a4712 285 PRINTS PR00990 Ribokinase signature 34 53 1.0E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 STK_05740 5323214e72c80864346a6d664c3a4712 285 Pfam PF00294 pfkB family carbohydrate kinase 7 139 9.1E-16 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB STK_05740 5323214e72c80864346a6d664c3a4712 285 Pfam PF00294 pfkB family carbohydrate kinase 181 265 5.3E-18 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB STK_05740 5323214e72c80864346a6d664c3a4712 285 Gene3D G3DSA:3.40.1190.20 4 278 4.4E-53 T 23-10-2018 IPR029056 Ribokinase-like STK_05740 5323214e72c80864346a6d664c3a4712 285 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 39 63 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 STK_05740 5323214e72c80864346a6d664c3a4712 285 SUPERFAMILY SSF53613 7 275 6.7E-51 T 23-10-2018 IPR029056 Ribokinase-like STK_00280 1976c6ad9580cf72d37e5d2fce6b952b 159 Gene3D G3DSA:3.30.70.2780 61 130 6.2E-73 T 23-10-2018 STK_00280 1976c6ad9580cf72d37e5d2fce6b952b 159 Gene3D G3DSA:1.20.120.1610 5 159 6.2E-73 T 23-10-2018 STK_16540 fd38267a744bd88d38f93f03c799eb9d 287 Pfam PF02754 Cysteine-rich domain 189 273 8.3E-7 T 23-10-2018 IPR004017 Cysteine-rich domain STK_09950 5b339128975492324b7b6e8283195303 160 Pfam PF01944 Stage II sporulation protein M 44 150 3.1E-8 T 23-10-2018 IPR002798 Stage II sporulation protein M-like STK_04670 6f06462d97d8382084233daa9d5942a6 686 SMART SM00350 103 598 6.1E-203 T 23-10-2018 IPR031327 Mini-chromosome maintenance protein STK_04670 6f06462d97d8382084233daa9d5942a6 686 Gene3D G3DSA:3.40.50.300 273 602 6.4E-136 T 23-10-2018 STK_04670 6f06462d97d8382084233daa9d5942a6 686 Gene3D G3DSA:2.20.28.10 138 184 6.9E-21 T 23-10-2018 STK_04670 6f06462d97d8382084233daa9d5942a6 686 Gene3D G3DSA:1.10.10.10 603 686 3.1E-30 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_04670 6f06462d97d8382084233daa9d5942a6 686 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 469 477 2.0E-30 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 STK_04670 6f06462d97d8382084233daa9d5942a6 686 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 390 404 2.0E-30 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 STK_04670 6f06462d97d8382084233daa9d5942a6 686 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 442 454 2.0E-30 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 STK_04670 6f06462d97d8382084233daa9d5942a6 686 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 418 431 2.0E-30 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 STK_04670 6f06462d97d8382084233daa9d5942a6 686 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 330 345 2.0E-30 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 STK_04670 6f06462d97d8382084233daa9d5942a6 686 Gene3D G3DSA:3.30.1640.10 2 103 8.1E-24 T 23-10-2018 STK_04670 6f06462d97d8382084233daa9d5942a6 686 SUPERFAMILY SSF52540 299 594 8.15E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_04670 6f06462d97d8382084233daa9d5942a6 686 Pfam PF00493 MCM2/3/5 family 276 594 5.0E-136 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 STK_04670 6f06462d97d8382084233daa9d5942a6 686 SUPERFAMILY SSF50249 12 258 1.44E-61 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_04670 6f06462d97d8382084233daa9d5942a6 686 Pfam PF14551 MCM N-terminal domain 14 100 1.9E-16 T 23-10-2018 IPR027925 MCM N-terminal domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 STK_04670 6f06462d97d8382084233daa9d5942a6 686 Pfam PF17207 MCM OB domain 107 238 1.2E-34 T 23-10-2018 IPR033762 MCM OB domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 STK_18830 93f2cb6e806995eef3a7266deca7aa79 450 PIRSF PIRSF032762 1 450 3.9E-265 T 23-10-2018 IPR017007 Uncharacterised conserved protein UCP032762 STK_18830 93f2cb6e806995eef3a7266deca7aa79 450 Pfam PF07849 Protein of unknown function (DUF1641) 408 446 1.3E-10 T 23-10-2018 IPR012440 Protein of unknown function DUF1641 STK_06640 3a54e03bf46d139aaea94b0668f024f5 461 PIRSF PIRSF004919 1 459 4.8E-154 T 23-10-2018 IPR025502 TldD STK_06640 3a54e03bf46d139aaea94b0668f024f5 461 Pfam PF01523 Putative modulator of DNA gyrase 15 308 5.5E-42 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 STK_06640 3a54e03bf46d139aaea94b0668f024f5 461 SUPERFAMILY SSF111283 6 455 8.5E-87 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 STK_17955 3b3b890832f67cb38fd18c40b889e60c 89 Gene3D G3DSA:3.30.70.20 6 85 3.4E-11 T 23-10-2018 STK_17955 3b3b890832f67cb38fd18c40b889e60c 89 Pfam PF13237 4Fe-4S dicluster domain 20 71 4.2E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_17955 3b3b890832f67cb38fd18c40b889e60c 89 SUPERFAMILY SSF54862 4 82 6.51E-19 T 23-10-2018 STK_17955 3b3b890832f67cb38fd18c40b889e60c 89 PIRSF PIRSF036548 2 89 6.3E-18 T 23-10-2018 IPR012206 Ferredoxin-like, FixX GO:0005506 STK_22220 a5949c13ffa6862fa8b7928d1cbfe8e9 1138 Pfam PF00361 Proton-conducting membrane transporter 666 941 3.4E-30 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_22220 a5949c13ffa6862fa8b7928d1cbfe8e9 1138 Pfam PF00361 Proton-conducting membrane transporter 122 408 3.1E-46 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_22220 a5949c13ffa6862fa8b7928d1cbfe8e9 1138 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 732 753 8.0E-18 T 23-10-2018 STK_22220 a5949c13ffa6862fa8b7928d1cbfe8e9 1138 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 565 590 8.0E-18 T 23-10-2018 STK_22220 a5949c13ffa6862fa8b7928d1cbfe8e9 1138 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 754 780 8.0E-18 T 23-10-2018 STK_08800 5d33dbfb7a11dcfd57a2067c6e1ca8b6 321 Pfam PF01206 Sulfurtransferase TusA 130 195 2.4E-14 T 23-10-2018 IPR001455 TusA-like domain STK_08800 5d33dbfb7a11dcfd57a2067c6e1ca8b6 321 SUPERFAMILY SSF64307 106 197 1.1E-17 T 23-10-2018 IPR036868 TusA-like domain superfamily STK_08800 5d33dbfb7a11dcfd57a2067c6e1ca8b6 321 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 131 155 - T 23-10-2018 IPR001455 TusA-like domain STK_08800 5d33dbfb7a11dcfd57a2067c6e1ca8b6 321 Gene3D G3DSA:3.30.110.40 126 198 2.4E-15 T 23-10-2018 IPR036868 TusA-like domain superfamily STK_01120 ede010a625738c9f63b51ee727857a8d 243 SUPERFAMILY SSF46785 1 59 3.62E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_01120 ede010a625738c9f63b51ee727857a8d 243 SMART SM00344 1 90 0.0085 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 STK_01120 ede010a625738c9f63b51ee727857a8d 243 Gene3D G3DSA:1.10.10.10 107 165 5.7E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_01120 ede010a625738c9f63b51ee727857a8d 243 Pfam PF13412 Winged helix-turn-helix DNA-binding 116 163 1.2E-10 T 23-10-2018 STK_01120 ede010a625738c9f63b51ee727857a8d 243 Pfam PF13412 Winged helix-turn-helix DNA-binding 14 43 1.6E-7 T 23-10-2018 STK_01120 ede010a625738c9f63b51ee727857a8d 243 SUPERFAMILY SSF46785 114 174 2.53E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_01120 ede010a625738c9f63b51ee727857a8d 243 Gene3D G3DSA:1.10.10.10 1 50 3.1E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_10260 8b9a196acd31c9b13120dbde2266526f 198 Pfam PF01730 UreF 38 164 1.3E-14 T 23-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 STK_10260 8b9a196acd31c9b13120dbde2266526f 198 PIRSF PIRSF009467 3 198 2.9E-31 T 23-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 STK_10260 8b9a196acd31c9b13120dbde2266526f 198 Gene3D G3DSA:1.10.4190.10 3 175 1.9E-29 T 23-10-2018 IPR038277 UreF domain superfamily STK_08710 49dabe704dc4024d93847c4bc5dbd470 178 SUPERFAMILY SSF53335 3 175 9.91E-17 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_08710 49dabe704dc4024d93847c4bc5dbd470 178 Pfam PF08241 Methyltransferase domain 46 140 3.0E-12 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 STK_08710 49dabe704dc4024d93847c4bc5dbd470 178 Gene3D G3DSA:3.40.50.150 25 177 1.3E-17 T 23-10-2018 STK_16390 2e1ab05a9ddcc62dafdd53c0ffe70e50 138 Gene3D G3DSA:3.40.50.1010 2 127 3.2E-26 T 23-10-2018 STK_16390 2e1ab05a9ddcc62dafdd53c0ffe70e50 138 Pfam PF01850 PIN domain 3 121 2.6E-12 T 23-10-2018 IPR002716 PIN domain STK_16390 2e1ab05a9ddcc62dafdd53c0ffe70e50 138 SUPERFAMILY SSF88723 3 130 1.91E-18 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_20140 aa2632b165d91fa68b3d836ccde5f474 158 Pfam PF05942 Archaeal PaREP1/PaREP8 family 18 144 2.2E-24 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_06300 1d64582c5258661210b31b77655f727d 318 Pfam PF01171 PP-loop family 49 229 5.7E-16 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 STK_06300 1d64582c5258661210b31b77655f727d 318 PIRSF PIRSF004976 1 318 1.8E-95 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 STK_06300 1d64582c5258661210b31b77655f727d 318 Gene3D G3DSA:3.40.50.620 1 317 1.7E-72 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_06300 1d64582c5258661210b31b77655f727d 318 ProSitePatterns PS01263 Uncharacterized protein family UPF0021 signature. 22 59 - T 23-10-2018 IPR020554 Uncharacterised protein family UPF0021, conserved site STK_06300 1d64582c5258661210b31b77655f727d 318 SUPERFAMILY SSF52402 24 253 1.54E-45 T 23-10-2018 STK_15120 9a74c05e711889c3cf063dc4e7bb6235 146 Gene3D G3DSA:1.10.3450.10 64 136 1.3E-12 T 23-10-2018 STK_15120 9a74c05e711889c3cf063dc4e7bb6235 146 Pfam PF03745 Domain of unknown function (DUF309) 65 116 1.8E-14 T 23-10-2018 IPR005500 Protein of unknown function DUF309 STK_15120 9a74c05e711889c3cf063dc4e7bb6235 146 SUPERFAMILY SSF140663 56 135 1.07E-18 T 23-10-2018 IPR023203 TTHA0068-like superfamily STK_07620 3728c26abf76182bf490b14cf69a921c 533 SUPERFAMILY SSF52540 109 515 1.93E-29 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_07620 3728c26abf76182bf490b14cf69a921c 533 Gene3D G3DSA:3.40.50.300 117 258 4.5E-17 T 23-10-2018 STK_07620 3728c26abf76182bf490b14cf69a921c 533 Gene3D G3DSA:3.40.50.300 324 519 1.7E-32 T 23-10-2018 STK_07620 3728c26abf76182bf490b14cf69a921c 533 Pfam PF01935 Domain of unknown function DUF87 134 380 6.5E-43 T 23-10-2018 IPR002789 Helicase HerA, central domain STK_19430 a9a6a7d3dac9a34f085156a61ee25536 130 Pfam PF01850 PIN domain 5 121 4.1E-15 T 23-10-2018 IPR002716 PIN domain STK_19430 a9a6a7d3dac9a34f085156a61ee25536 130 SMART SM00670 2 119 0.0027 T 23-10-2018 IPR002716 PIN domain STK_19430 a9a6a7d3dac9a34f085156a61ee25536 130 Gene3D G3DSA:3.40.50.1010 2 130 1.9E-34 T 23-10-2018 STK_19430 a9a6a7d3dac9a34f085156a61ee25536 130 SUPERFAMILY SSF88723 2 129 3.08E-35 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_18990 09610a17d0489c86279c1d666eb716ce 136 Gene3D G3DSA:3.30.300.20 2 123 8.5E-22 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta STK_18990 09610a17d0489c86279c1d666eb716ce 136 Pfam PF02566 OsmC-like protein 31 131 5.7E-19 T 23-10-2018 IPR003718 OsmC/Ohr family STK_18990 09610a17d0489c86279c1d666eb716ce 136 SUPERFAMILY SSF82784 23 134 1.23E-23 T 23-10-2018 IPR036102 OsmC/Ohr superfamily STK_25480 cda838009b78ba9595ff01d0eb6544c6 295 Pfam PF06675 Protein of unknown function (DUF1177) 35 293 1.4E-102 T 23-10-2018 IPR009561 Protein of unknown function DUF1177 STK_21750 4d49dc7b05318b753ca66c94ab8896f7 245 SUPERFAMILY SSF53335 21 242 4.29E-41 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_21750 4d49dc7b05318b753ca66c94ab8896f7 245 Pfam PF13649 Methyltransferase domain 46 138 1.8E-17 T 23-10-2018 STK_21750 4d49dc7b05318b753ca66c94ab8896f7 245 Gene3D G3DSA:2.20.25.110 146 202 5.4E-45 T 23-10-2018 STK_21750 4d49dc7b05318b753ca66c94ab8896f7 245 Gene3D G3DSA:3.40.50.150 24 226 5.4E-45 T 23-10-2018 STK_14390 6cb7d9421bc11e8df7c3289d9b3a2750 101 Pfam PF00137 ATP synthase subunit C 37 96 3.0E-13 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 STK_14390 6cb7d9421bc11e8df7c3289d9b3a2750 101 Gene3D G3DSA:1.20.120.610 8 99 8.2E-14 T 23-10-2018 STK_14390 6cb7d9421bc11e8df7c3289d9b3a2750 101 SUPERFAMILY SSF81333 36 98 1.7E-11 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily STK_14390 6cb7d9421bc11e8df7c3289d9b3a2750 101 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 48 74 2.9E-5 T 23-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 STK_14390 6cb7d9421bc11e8df7c3289d9b3a2750 101 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 75 98 2.9E-5 T 23-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 STK_22090 d348871cd1b8900ff1994dfb8ab381af 183 Pfam PF10120 Thiamine-phosphate synthase 11 176 5.5E-53 T 23-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 STK_22090 d348871cd1b8900ff1994dfb8ab381af 183 SUPERFAMILY SSF53639 3 178 1.02E-53 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily STK_22090 d348871cd1b8900ff1994dfb8ab381af 183 Gene3D G3DSA:3.40.225.10 1 181 4.0E-56 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily STK_20530 e89d8af02f6a30755f917615dfd3630c 593 SUPERFAMILY SSF81442 19 490 3.14E-94 T 23-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_20530 e89d8af02f6a30755f917615dfd3630c 593 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 20 466 6.4E-70 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_20530 e89d8af02f6a30755f917615dfd3630c 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 372 391 2.1E-5 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_20530 e89d8af02f6a30755f917615dfd3630c 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 61 84 2.1E-5 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_20530 e89d8af02f6a30755f917615dfd3630c 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 423 444 2.1E-5 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_20530 e89d8af02f6a30755f917615dfd3630c 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 309 330 2.1E-5 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_20530 e89d8af02f6a30755f917615dfd3630c 593 Gene3D G3DSA:1.20.210.10 11 512 3.6E-80 T 23-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_14790 cda5f7c36510b6ab78d49b14e09cc276 160 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 7 152 1.7E-51 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 STK_14790 cda5f7c36510b6ab78d49b14e09cc276 160 Gene3D G3DSA:2.30.30.20 101 160 2.4E-23 T 23-10-2018 STK_14790 cda5f7c36510b6ab78d49b14e09cc276 160 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 104 151 1.7E-13 T 23-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal STK_14790 cda5f7c36510b6ab78d49b14e09cc276 160 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 11 100 4.0E-43 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal STK_14790 cda5f7c36510b6ab78d49b14e09cc276 160 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 6 153 32.927 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 STK_14790 cda5f7c36510b6ab78d49b14e09cc276 160 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 10 99 1.6E-33 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal STK_14790 cda5f7c36510b6ab78d49b14e09cc276 160 SUPERFAMILY SSF57825 102 155 1.03E-13 T 23-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily STK_14790 cda5f7c36510b6ab78d49b14e09cc276 160 SUPERFAMILY SSF54893 5 101 2.35E-34 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily STK_14790 cda5f7c36510b6ab78d49b14e09cc276 160 Gene3D G3DSA:3.30.70.140 1 100 1.2E-38 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily STK_00450 db0da80cd4410d3553a2c108c68cdd0f 225 SUPERFAMILY SSF56003 7 208 2.22E-41 T 23-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 STK_00450 db0da80cd4410d3553a2c108c68cdd0f 225 Gene3D G3DSA:3.30.365.20 5 217 1.8E-42 T 23-10-2018 STK_00450 db0da80cd4410d3553a2c108c68cdd0f 225 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 7 170 1.5E-25 T 23-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 STK_05180 97173578f0724505ae916c247e8ffb1f 236 Pfam PF04981 NMD3 family 6 236 4.1E-43 T 23-10-2018 IPR007064 Nmd3, N-terminal STK_05250 340fa7fd534d79ee15b1632fede53f3e 179 Gene3D G3DSA:1.10.3210.10 4 177 4.9E-38 T 23-10-2018 STK_05250 340fa7fd534d79ee15b1632fede53f3e 179 SMART SM00471 27 139 1.2E-10 T 23-10-2018 IPR003607 HD/PDEase domain STK_05250 340fa7fd534d79ee15b1632fede53f3e 179 SUPERFAMILY SSF109604 11 154 5.8E-29 T 23-10-2018 STK_05250 340fa7fd534d79ee15b1632fede53f3e 179 Pfam PF13023 HD domain 11 146 4.0E-17 T 23-10-2018 IPR006674 HD domain STK_06620 70f33089bd13c37cef6e0aa13c754ea4 113 Pfam PF01909 Nucleotidyltransferase domain 23 107 6.2E-12 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_06620 70f33089bd13c37cef6e0aa13c754ea4 113 SUPERFAMILY SSF81301 31 111 4.44E-20 T 23-10-2018 STK_06620 70f33089bd13c37cef6e0aa13c754ea4 113 Gene3D G3DSA:3.30.460.10 20 113 1.7E-28 T 23-10-2018 STK_06860 d6338910c24b5acab08eb2c72cf099f6 644 SMART SM00220 336 643 2.4E-28 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 STK_06860 d6338910c24b5acab08eb2c72cf099f6 644 Gene3D G3DSA:1.10.510.10 443 644 2.5E-30 T 23-10-2018 STK_06860 d6338910c24b5acab08eb2c72cf099f6 644 Gene3D G3DSA:3.30.200.20 334 442 4.0E-9 T 23-10-2018 STK_06860 d6338910c24b5acab08eb2c72cf099f6 644 Pfam PF00069 Protein kinase domain 336 640 1.6E-34 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 STK_06860 d6338910c24b5acab08eb2c72cf099f6 644 SUPERFAMILY SSF56112 331 641 1.37E-47 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily STK_06860 d6338910c24b5acab08eb2c72cf099f6 644 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 342 363 - T 23-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 STK_06860 d6338910c24b5acab08eb2c72cf099f6 644 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 480 492 - T 23-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 STK_21930 10b04abac7644602dda48dc690863b8f 327 Pfam PF00535 Glycosyl transferase family 2 5 127 9.1E-17 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 STK_21930 10b04abac7644602dda48dc690863b8f 327 SUPERFAMILY SSF53448 4 217 2.25E-26 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_21930 10b04abac7644602dda48dc690863b8f 327 Gene3D G3DSA:3.90.550.10 1 206 8.9E-23 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_17710 f92de82489ee84d3f7059a70d649421c 294 Pfam PF01061 ABC-2 type transporter 19 259 1.8E-37 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 STK_17710 f92de82489ee84d3f7059a70d649421c 294 PRINTS PR00164 ABC-2 type transport system membrane protein signature 217 236 5.8E-9 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 STK_17710 f92de82489ee84d3f7059a70d649421c 294 PRINTS PR00164 ABC-2 type transport system membrane protein signature 237 256 5.8E-9 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 STK_17710 f92de82489ee84d3f7059a70d649421c 294 PRINTS PR00164 ABC-2 type transport system membrane protein signature 95 117 5.8E-9 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 STK_17710 f92de82489ee84d3f7059a70d649421c 294 PRINTS PR00164 ABC-2 type transport system membrane protein signature 142 167 5.8E-9 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 STK_17710 f92de82489ee84d3f7059a70d649421c 294 PIRSF PIRSF006648 1 293 1.1E-91 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 STK_01040 ef9497261dba11ff28b964e0ea2fa7b7 197 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 2 25 4.8E-4 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal STK_01040 ef9497261dba11ff28b964e0ea2fa7b7 197 PIRSF PIRSF022145 1 197 2.1E-90 T 23-10-2018 IPR010532 Sulfocyanin GO:0005507|GO:0055114 STK_01040 ef9497261dba11ff28b964e0ea2fa7b7 197 Gene3D G3DSA:2.60.40.420 25 185 3.9E-20 T 23-10-2018 IPR008972 Cupredoxin STK_01040 ef9497261dba11ff28b964e0ea2fa7b7 197 SUPERFAMILY SSF49503 48 184 1.15E-20 T 23-10-2018 IPR008972 Cupredoxin STK_01040 ef9497261dba11ff28b964e0ea2fa7b7 197 TIGRFAM TIGR03094 sulfo_cyanin: sulfocyanin 5 196 6.6E-92 T 23-10-2018 IPR010532 Sulfocyanin GO:0005507|GO:0055114 STK_01040 ef9497261dba11ff28b964e0ea2fa7b7 197 ProSitePatterns PS00079 Multicopper oxidases signature 1. 163 183 - T 23-10-2018 IPR033138 Multicopper oxidases, conserved site STK_01040 ef9497261dba11ff28b964e0ea2fa7b7 197 Pfam PF06525 Sulfocyanin (SoxE) domain 51 196 7.1E-68 T 23-10-2018 IPR010532 Sulfocyanin GO:0005507|GO:0055114 STK_25560 9ddcb9558a7a3bec9835617abb01df0b 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 236 2.7E-50 T 23-10-2018 STK_25560 9ddcb9558a7a3bec9835617abb01df0b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 7.6E-34 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_25560 9ddcb9558a7a3bec9835617abb01df0b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.6E-34 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_25560 9ddcb9558a7a3bec9835617abb01df0b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 7.6E-34 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_25560 9ddcb9558a7a3bec9835617abb01df0b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 7.6E-34 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_25560 9ddcb9558a7a3bec9835617abb01df0b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 7.6E-34 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_25560 9ddcb9558a7a3bec9835617abb01df0b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 7.6E-34 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_25560 9ddcb9558a7a3bec9835617abb01df0b 253 SUPERFAMILY SSF51735 6 239 1.22E-68 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_25560 9ddcb9558a7a3bec9835617abb01df0b 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 1.2E-8 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_25560 9ddcb9558a7a3bec9835617abb01df0b 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 1.2E-8 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_25560 9ddcb9558a7a3bec9835617abb01df0b 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 1.2E-8 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_25560 9ddcb9558a7a3bec9835617abb01df0b 253 Gene3D G3DSA:3.40.50.720 1 247 2.4E-68 T 23-10-2018 STK_23230 5eb0138a73b931a03baa5496144f7a53 353 Gene3D G3DSA:3.40.350.10 1 124 3.0E-25 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal STK_23230 5eb0138a73b931a03baa5496144f7a53 353 Gene3D G3DSA:3.90.230.10 125 352 4.1E-75 T 23-10-2018 STK_23230 5eb0138a73b931a03baa5496144f7a53 353 Pfam PF01321 Creatinase/Prolidase N-terminal domain 3 127 4.6E-16 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 STK_23230 5eb0138a73b931a03baa5496144f7a53 353 SUPERFAMILY SSF53092 1 125 6.41E-19 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal STK_23230 5eb0138a73b931a03baa5496144f7a53 353 SUPERFAMILY SSF55920 126 338 5.23E-69 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like STK_23230 5eb0138a73b931a03baa5496144f7a53 353 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 283 295 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site STK_23230 5eb0138a73b931a03baa5496144f7a53 353 Pfam PF00557 Metallopeptidase family M24 135 336 1.1E-63 T 23-10-2018 IPR000994 Peptidase M24 STK_17160 64bc9fd5e72d363e33e5130c8dac793c 170 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 49 3.8E-11 T 23-10-2018 STK_17160 64bc9fd5e72d363e33e5130c8dac793c 170 Gene3D G3DSA:1.10.10.10 1 53 1.3E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_17160 64bc9fd5e72d363e33e5130c8dac793c 170 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 2.3E-8 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_17160 64bc9fd5e72d363e33e5130c8dac793c 170 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 2.3E-8 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_17160 64bc9fd5e72d363e33e5130c8dac793c 170 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 2.3E-8 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 STK_17160 64bc9fd5e72d363e33e5130c8dac793c 170 SMART SM00746 125 161 1.0E-7 T 23-10-2018 IPR011017 TRASH domain STK_17160 64bc9fd5e72d363e33e5130c8dac793c 170 SUPERFAMILY SSF46785 4 50 1.18E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_17160 64bc9fd5e72d363e33e5130c8dac793c 170 Pfam PF08394 Archaeal TRASH domain 125 161 4.5E-19 T 23-10-2018 IPR013603 TRASH transcription regulator C-terminal, archaeal STK_18380 2d08146e875cf582598bfdf96f055333 216 Gene3D G3DSA:1.10.3480.10 5 210 2.0E-25 T 23-10-2018 STK_18380 2d08146e875cf582598bfdf96f055333 216 Pfam PF02613 Nitrate reductase delta subunit 61 180 6.4E-15 T 23-10-2018 IPR020945 DMSO/Nitrate reductase chaperone STK_18380 2d08146e875cf582598bfdf96f055333 216 SUPERFAMILY SSF89155 6 210 1.96E-33 T 23-10-2018 IPR036411 TorD-like superfamily STK_10410 1ad44a53edb775399ae41e54a9f0be18 191 Gene3D G3DSA:1.20.910.10 2 187 2.5E-10 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 STK_10410 1ad44a53edb775399ae41e54a9f0be18 191 SUPERFAMILY SSF48613 2 182 2.45E-34 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 STK_10410 1ad44a53edb775399ae41e54a9f0be18 191 Pfam PF03070 TENA/THI-4/PQQC family 26 180 6.4E-6 T 23-10-2018 IPR004305 Thiaminase-2/PQQC STK_24940 7bfaf6715c3474d45997490f98f06707 191 Pfam PF09335 SNARE associated Golgi protein 26 152 9.5E-20 T 23-10-2018 IPR032816 SNARE associated Golgi protein STK_21970 4d3c543c40c8cbce1109feabcacb7429 467 Pfam PF13620 Carboxypeptidase regulatory-like domain 129 211 1.1E-8 T 23-10-2018 STK_21970 4d3c543c40c8cbce1109feabcacb7429 467 Gene3D G3DSA:1.20.5.340 327 439 2.4E-12 T 23-10-2018 STK_21970 4d3c543c40c8cbce1109feabcacb7429 467 Pfam PF08614 Autophagy protein 16 (ATG16) 339 435 3.6E-8 T 23-10-2018 IPR013923 Autophagy-related protein 16 STK_21970 4d3c543c40c8cbce1109feabcacb7429 467 SUPERFAMILY SSF58100 333 462 6.8E-11 T 23-10-2018 STK_21970 4d3c543c40c8cbce1109feabcacb7429 467 SUPERFAMILY SSF49464 132 218 1.06E-7 T 23-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily STK_21970 4d3c543c40c8cbce1109feabcacb7429 467 Gene3D G3DSA:2.60.40.1120 130 213 2.2E-7 T 23-10-2018 STK_08410 538451a1424412381dcb35f53f5666d2 325 Pfam PF01032 FecCD transport family 10 316 1.6E-67 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 STK_08410 538451a1424412381dcb35f53f5666d2 325 SUPERFAMILY SSF81345 4 316 2.09E-58 T 23-10-2018 IPR037294 ABC transporter, BtuC-like STK_08410 538451a1424412381dcb35f53f5666d2 325 Gene3D G3DSA:1.10.3470.10 1 318 1.1E-67 T 23-10-2018 IPR037294 ABC transporter, BtuC-like STK_18150 01794ad5b16470a8e096054ba857898a 122 Pfam PF03625 Domain of unknown function DUF302 32 92 7.6E-19 T 23-10-2018 IPR005180 Domain of unknown function DUF302 STK_18150 01794ad5b16470a8e096054ba857898a 122 Gene3D G3DSA:3.30.310.70 1 121 3.4E-19 T 23-10-2018 IPR035923 TT1751-like domain superfamily STK_18150 01794ad5b16470a8e096054ba857898a 122 SUPERFAMILY SSF103247 2 121 1.27E-31 T 23-10-2018 IPR035923 TT1751-like domain superfamily STK_04120 3d459243062038579cd6427fc24a4795 144 Gene3D G3DSA:3.100.10.10 60 142 1.6E-13 T 23-10-2018 STK_04120 3d459243062038579cd6427fc24a4795 144 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 36 139 4.1E-14 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P STK_04120 3d459243062038579cd6427fc24a4795 144 SUPERFAMILY SSF52080 7 141 1.96E-29 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily STK_04120 3d459243062038579cd6427fc24a4795 144 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 1 141 12.188 T 23-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 STK_16650 adf6b7d9a59bb572b93659f61ace0447 314 TIGRFAM TIGR03155 sulfolob_CbsB: cytochrome b558/566, subunit B 7 306 2.2E-148 T 23-10-2018 IPR017573 Cytochrome b558/566, subunit B STK_15315 2c6d83308dff4153105406be3bae986c 88 SUPERFAMILY SSF54862 13 85 8.7E-23 T 23-10-2018 STK_15315 2c6d83308dff4153105406be3bae986c 88 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 66 77 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_15315 2c6d83308dff4153105406be3bae986c 88 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 10 86 1.2E-34 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 STK_15315 2c6d83308dff4153105406be3bae986c 88 Pfam PF14697 4Fe-4S dicluster domain 30 83 7.9E-11 T 23-10-2018 STK_15315 2c6d83308dff4153105406be3bae986c 88 Gene3D G3DSA:3.30.70.20 57 88 1.1E-8 T 23-10-2018 STK_15315 2c6d83308dff4153105406be3bae986c 88 Gene3D G3DSA:3.30.70.20 10 56 1.7E-6 T 23-10-2018 STK_03380 ef8e6b40e558ee943af4ed2fcb45404f 134 Gene3D G3DSA:1.20.120.330 6 127 3.7E-16 T 23-10-2018 STK_03380 ef8e6b40e558ee943af4ed2fcb45404f 134 Pfam PF05168 HEPN domain 8 125 1.5E-24 T 23-10-2018 IPR007842 HEPN domain STK_03380 ef8e6b40e558ee943af4ed2fcb45404f 134 SUPERFAMILY SSF81593 8 128 2.9E-23 T 23-10-2018 STK_03380 ef8e6b40e558ee943af4ed2fcb45404f 134 SMART SM00748 9 119 2.0E-22 T 23-10-2018 IPR007842 HEPN domain STK_02930 3d85c9f836d638cd1e84c3175071393b 321 Gene3D G3DSA:3.30.70.3460 197 318 4.4E-15 T 23-10-2018 STK_02930 3d85c9f836d638cd1e84c3175071393b 321 Gene3D G3DSA:3.30.70.3460 66 173 9.2E-15 T 23-10-2018 STK_02930 3d85c9f836d638cd1e84c3175071393b 321 Gene3D G3DSA:1.10.10.10 3 54 4.9E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_02930 3d85c9f836d638cd1e84c3175071393b 321 SUPERFAMILY SSF46785 3 62 1.92E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_02930 3d85c9f836d638cd1e84c3175071393b 321 SUPERFAMILY SSF46785 192 234 1.26E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_24530 45d7667f024edbe7d4e408f5eccd0260 336 Gene3D G3DSA:3.40.50.720 123 257 2.5E-27 T 23-10-2018 STK_24530 45d7667f024edbe7d4e408f5eccd0260 336 SUPERFAMILY SSF81324 11 140 3.79E-8 T 23-10-2018 STK_24530 45d7667f024edbe7d4e408f5eccd0260 336 Gene3D G3DSA:1.10.287.70 25 116 6.7E-9 T 23-10-2018 STK_24530 45d7667f024edbe7d4e408f5eccd0260 336 Pfam PF02254 TrkA-N domain 130 241 5.2E-16 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 STK_24530 45d7667f024edbe7d4e408f5eccd0260 336 SUPERFAMILY SSF51735 126 262 2.85E-24 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_20885 9bf8381caaff9c9e7975ad539ca13e29 82 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 14 38 - T 23-10-2018 IPR001455 TusA-like domain STK_20885 9bf8381caaff9c9e7975ad539ca13e29 82 SUPERFAMILY SSF64307 5 80 3.79E-23 T 23-10-2018 IPR036868 TusA-like domain superfamily STK_20885 9bf8381caaff9c9e7975ad539ca13e29 82 Pfam PF01206 Sulfurtransferase TusA 13 80 1.2E-19 T 23-10-2018 IPR001455 TusA-like domain STK_20885 9bf8381caaff9c9e7975ad539ca13e29 82 Gene3D G3DSA:3.30.110.40 9 80 9.2E-21 T 23-10-2018 IPR036868 TusA-like domain superfamily STK_05370 55a84d3bed88c3edba0548cd13deb748 206 Pfam PF13483 Beta-lactamase superfamily domain 2 159 2.4E-33 T 23-10-2018 STK_05370 55a84d3bed88c3edba0548cd13deb748 206 Gene3D G3DSA:3.60.15.10 1 205 6.0E-48 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_05370 55a84d3bed88c3edba0548cd13deb748 206 SUPERFAMILY SSF56281 3 187 1.96E-25 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_21230 e80e77a8202df757afc392972b6d2d58 132 Pfam PF00085 Thioredoxin 29 127 3.3E-27 T 23-10-2018 IPR013766 Thioredoxin domain GO:0045454 STK_21230 e80e77a8202df757afc392972b6d2d58 132 PRINTS PR00421 Thioredoxin family signature 47 55 3.7E-7 T 23-10-2018 STK_21230 e80e77a8202df757afc392972b6d2d58 132 PRINTS PR00421 Thioredoxin family signature 55 64 3.7E-7 T 23-10-2018 STK_21230 e80e77a8202df757afc392972b6d2d58 132 PRINTS PR00421 Thioredoxin family signature 94 105 3.7E-7 T 23-10-2018 STK_21230 e80e77a8202df757afc392972b6d2d58 132 Gene3D G3DSA:3.40.30.10 23 131 7.6E-35 T 23-10-2018 STK_21230 e80e77a8202df757afc392972b6d2d58 132 PIRSF PIRSF000077 26 130 4.9E-32 T 23-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 STK_21230 e80e77a8202df757afc392972b6d2d58 132 ProSitePatterns PS00194 Thioredoxin family active site. 48 66 - T 23-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 STK_21230 e80e77a8202df757afc392972b6d2d58 132 SUPERFAMILY SSF52833 12 131 9.74E-40 T 23-10-2018 IPR036249 Thioredoxin-like superfamily STK_21230 e80e77a8202df757afc392972b6d2d58 132 TIGRFAM TIGR01068 thioredoxin: thioredoxin 33 128 3.0E-33 T 23-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 STK_22240 02646ad98cb315c8cbc7d89870ba1d73 347 SUPERFAMILY SSF55347 176 282 4.45E-29 T 23-10-2018 STK_22240 02646ad98cb315c8cbc7d89870ba1d73 347 Gene3D G3DSA:3.40.50.720 2 321 1.8E-75 T 23-10-2018 STK_22240 02646ad98cb315c8cbc7d89870ba1d73 347 SUPERFAMILY SSF51735 2 329 4.13E-63 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_22240 02646ad98cb315c8cbc7d89870ba1d73 347 Gene3D G3DSA:3.30.360.10 177 282 1.8E-75 T 23-10-2018 STK_22240 02646ad98cb315c8cbc7d89870ba1d73 347 Pfam PF01658 Myo-inositol-1-phosphate synthase 178 281 2.5E-20 T 23-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 STK_05380 d3b3e1d40ade563fdc46756c012165e2 386 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 19 35 - T 23-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 STK_05380 d3b3e1d40ade563fdc46756c012165e2 386 Gene3D G3DSA:3.20.20.70 9 277 1.1E-107 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_05380 d3b3e1d40ade563fdc46756c012165e2 386 Gene3D G3DSA:1.10.238.260 278 385 1.9E-32 T 23-10-2018 STK_05380 d3b3e1d40ade563fdc46756c012165e2 386 SUPERFAMILY SSF51569 8 289 4.03E-100 T 23-10-2018 STK_05380 d3b3e1d40ade563fdc46756c012165e2 386 TIGRFAM TIGR02090 LEU1_arch: isopropylmalate/citramalate/homocitrate synthases 12 375 7.4E-188 T 23-10-2018 IPR011830 Isopropylmalate/citramalate/homocitrate synthase GO:0019752|GO:0046912 STK_05380 d3b3e1d40ade563fdc46756c012165e2 386 Pfam PF00682 HMGL-like 11 271 2.7E-93 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 STK_05380 d3b3e1d40ade563fdc46756c012165e2 386 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 200 213 - T 23-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 STK_12170 f0a6fb106f5715780f85c4ea92fac749 372 SUPERFAMILY SSF53383 2 348 4.87E-77 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase STK_12170 f0a6fb106f5715780f85c4ea92fac749 372 Gene3D G3DSA:3.90.1150.10 2 345 1.1E-89 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 STK_12170 f0a6fb106f5715780f85c4ea92fac749 372 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 176 196 - T 23-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site STK_12170 f0a6fb106f5715780f85c4ea92fac749 372 Gene3D G3DSA:3.40.640.10 11 252 1.1E-89 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 STK_12170 f0a6fb106f5715780f85c4ea92fac749 372 PIRSF PIRSF000524 1 355 3.0E-84 T 23-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 STK_12170 f0a6fb106f5715780f85c4ea92fac749 372 Pfam PF00266 Aminotransferase class-V 22 331 3.7E-28 T 23-10-2018 IPR000192 Aminotransferase class V domain STK_08380 d8a9228f5014d6a735095efb12c8a5c3 224 SUPERFAMILY SSF52540 5 211 3.37E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_08380 d8a9228f5014d6a735095efb12c8a5c3 224 Pfam PF06745 KaiC 4 208 1.8E-17 T 23-10-2018 IPR014774 KaiC-like domain STK_08380 d8a9228f5014d6a735095efb12c8a5c3 224 Gene3D G3DSA:3.40.50.300 3 216 1.7E-27 T 23-10-2018 STK_08380 d8a9228f5014d6a735095efb12c8a5c3 224 SMART SM00382 18 176 1.4E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_24040 16b34c8de0def5991418343eab5e6b6a 294 PIRSF PIRSF006232 1 292 6.9E-90 T 23-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 STK_24040 16b34c8de0def5991418343eab5e6b6a 294 SUPERFAMILY SSF51182 1 288 5.3E-75 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily STK_24040 16b34c8de0def5991418343eab5e6b6a 294 Gene3D G3DSA:2.60.120.10 152 253 6.0E-84 T 23-10-2018 IPR014710 RmlC-like jelly roll fold STK_24040 16b34c8de0def5991418343eab5e6b6a 294 Gene3D G3DSA:2.60.120.10 16 279 6.0E-84 T 23-10-2018 IPR014710 RmlC-like jelly roll fold STK_24040 16b34c8de0def5991418343eab5e6b6a 294 Pfam PF02678 Pirin 20 132 1.3E-37 T 23-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 STK_24040 16b34c8de0def5991418343eab5e6b6a 294 Pfam PF05726 Pirin C-terminal cupin domain 186 283 1.8E-26 T 23-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 STK_20820 4ec1f9a54c21c232d2df15a026340b8c 360 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 101 120 2.9E-19 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 STK_20820 4ec1f9a54c21c232d2df15a026340b8c 360 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 124 138 2.9E-19 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 STK_20820 4ec1f9a54c21c232d2df15a026340b8c 360 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 140 155 2.9E-19 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 STK_20820 4ec1f9a54c21c232d2df15a026340b8c 360 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 156 168 2.9E-19 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 STK_20820 4ec1f9a54c21c232d2df15a026340b8c 360 SUPERFAMILY SSF50156 203 291 9.82E-7 T 23-10-2018 IPR036034 PDZ superfamily GO:0005515 STK_20820 4ec1f9a54c21c232d2df15a026340b8c 360 Pfam PF02163 Peptidase family M50 115 346 1.1E-17 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 STK_20150 06c736e2e1830d6fde577c4ce8e805a9 100 Gene3D G3DSA:1.10.10.10 48 96 3.4E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_20150 06c736e2e1830d6fde577c4ce8e805a9 100 SUPERFAMILY SSF46689 49 98 4.35E-10 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 STK_20150 06c736e2e1830d6fde577c4ce8e805a9 100 Pfam PF13384 Homeodomain-like domain 52 91 1.2E-8 T 23-10-2018 STK_02502 1a5d896093ae38e2bd312158f6b5f537 79 Gene3D G3DSA:3.90.1530.10 3 78 3.0E-5 T 23-10-2018 STK_02502 1a5d896093ae38e2bd312158f6b5f537 79 Pfam PF02195 ParB-like nuclease domain 12 78 4.1E-7 T 23-10-2018 IPR003115 ParB/Sulfiredoxin STK_02502 1a5d896093ae38e2bd312158f6b5f537 79 SUPERFAMILY SSF110849 11 77 4.19E-10 T 23-10-2018 IPR036086 ParB/Sulfiredoxin superfamily STK_14990 27de547fd09362c1fb99e2ba352b2338 319 Gene3D G3DSA:3.90.650.10 155 314 7.2E-46 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily STK_14990 27de547fd09362c1fb99e2ba352b2338 319 SUPERFAMILY SSF55326 5 151 1.17E-33 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily STK_14990 27de547fd09362c1fb99e2ba352b2338 319 Pfam PF00586 AIR synthase related protein, N-terminal domain 45 149 2.5E-16 T 23-10-2018 IPR016188 PurM-like, N-terminal domain STK_14990 27de547fd09362c1fb99e2ba352b2338 319 SUPERFAMILY SSF56042 155 309 8.2E-39 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily STK_14990 27de547fd09362c1fb99e2ba352b2338 319 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 3 312 33.655 T 23-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 STK_14990 27de547fd09362c1fb99e2ba352b2338 319 Gene3D G3DSA:3.30.1330.10 1 154 4.4E-40 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily STK_14990 27de547fd09362c1fb99e2ba352b2338 319 Pfam PF02769 AIR synthase related protein, C-terminal domain 161 309 7.5E-24 T 23-10-2018 IPR010918 PurM-like, C-terminal domain STK_14990 27de547fd09362c1fb99e2ba352b2338 319 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 4 303 7.5E-88 T 23-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 STK_07594 8e1b0e44bdea030bbf723bd891d71f8a 67 Pfam PF11755 Protein of unknown function (DUF3311) 12 65 4.0E-11 T 23-10-2018 IPR021741 Protein of unknown function DUF3311 STK_24610 ab80ce6d4f318ae6caf412165a295447 296 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 127 279 2.0E-80 T 23-10-2018 IPR005642 Lysine exporter LysO STK_24610 ab80ce6d4f318ae6caf412165a295447 296 Pfam PF03956 Lysine exporter LysO 110 293 5.3E-47 T 23-10-2018 IPR005642 Lysine exporter LysO STK_13670 489d76b6d1b3d8926b20f601c9cccef7 219 Hamap MF_01318_A 50S ribosomal protein L1 [rplA]. 4 216 32.437 T 23-10-2018 IPR023669 Ribosomal protein L1, archaea GO:0003723|GO:0003735|GO:0006412|GO:0015934 STK_13670 489d76b6d1b3d8926b20f601c9cccef7 219 ProSitePatterns PS01199 Ribosomal protein L1 signature. 117 136 - T 23-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_13670 489d76b6d1b3d8926b20f601c9cccef7 219 PIRSF PIRSF002155 1 218 1.8E-61 T 23-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_13670 489d76b6d1b3d8926b20f601c9cccef7 219 Gene3D G3DSA:3.30.190.20 21 211 1.8E-65 T 23-10-2018 STK_13670 489d76b6d1b3d8926b20f601c9cccef7 219 SUPERFAMILY SSF56808 3 215 1.18E-54 T 23-10-2018 IPR023674 Ribosomal protein L1-like STK_13670 489d76b6d1b3d8926b20f601c9cccef7 219 Pfam PF00687 Ribosomal protein L1p/L10e family 23 210 2.3E-36 T 23-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein STK_13670 489d76b6d1b3d8926b20f601c9cccef7 219 Gene3D G3DSA:3.40.50.790 62 152 1.8E-65 T 23-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich STK_21810 142e5bab738d1ff6a87adbd8e0dce6ba 353 Pfam PF04693 Archaeal putative transposase ISC1217 1 325 1.6E-178 T 23-10-2018 IPR006783 Transposase, ISC1217 STK_00190 9bebb1039093d22944b59364a8edf1c0 460 SUPERFAMILY SSF160980 1 443 1.57E-56 T 23-10-2018 STK_00190 9bebb1039093d22944b59364a8edf1c0 460 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 4 411 4.7E-38 T 23-10-2018 IPR019016 CRISPR-associated DxTHG protein STK_00190 9bebb1039093d22944b59364a8edf1c0 460 Gene3D G3DSA:3.40.50.10640 2 188 8.1E-13 T 23-10-2018 STK_14620 e08970b647cc0358eadbd3e359623c47 249 SUPERFAMILY SSF51366 1 248 2.67E-80 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 STK_14620 e08970b647cc0358eadbd3e359623c47 249 Pfam PF00977 Histidine biosynthesis protein 5 231 1.2E-84 T 23-10-2018 IPR006062 Histidine biosynthesis GO:0000105 STK_14620 e08970b647cc0358eadbd3e359623c47 249 Gene3D G3DSA:3.20.20.70 1 249 3.2E-107 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_14620 e08970b647cc0358eadbd3e359623c47 249 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 248 6.7E-108 T 23-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 STK_14620 e08970b647cc0358eadbd3e359623c47 249 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 248 47.057 T 23-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 STK_23960 259801c4facf4659dd0813e02aafef1b 524 SUPERFAMILY SSF81442 8 505 1.7E-78 T 23-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_23960 259801c4facf4659dd0813e02aafef1b 524 Gene3D G3DSA:1.20.210.10 11 486 2.0E-74 T 23-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_23960 259801c4facf4659dd0813e02aafef1b 524 PRINTS PR01165 Cytochrome c oxidase subunit I signature 359 378 3.0E-23 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_23960 259801c4facf4659dd0813e02aafef1b 524 PRINTS PR01165 Cytochrome c oxidase subunit I signature 414 435 3.0E-23 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_23960 259801c4facf4659dd0813e02aafef1b 524 PRINTS PR01165 Cytochrome c oxidase subunit I signature 53 76 3.0E-23 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_23960 259801c4facf4659dd0813e02aafef1b 524 PRINTS PR01165 Cytochrome c oxidase subunit I signature 269 284 3.0E-23 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_23960 259801c4facf4659dd0813e02aafef1b 524 PRINTS PR01165 Cytochrome c oxidase subunit I signature 152 170 3.0E-23 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_23960 259801c4facf4659dd0813e02aafef1b 524 PRINTS PR01165 Cytochrome c oxidase subunit I signature 293 314 3.0E-23 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_23960 259801c4facf4659dd0813e02aafef1b 524 PRINTS PR01165 Cytochrome c oxidase subunit I signature 331 349 3.0E-23 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_23960 259801c4facf4659dd0813e02aafef1b 524 PRINTS PR01165 Cytochrome c oxidase subunit I signature 223 244 3.0E-23 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_23960 259801c4facf4659dd0813e02aafef1b 524 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 13 456 6.6E-69 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_23960 259801c4facf4659dd0813e02aafef1b 524 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 225 279 - T 23-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_12420 b0bd24f20ae6e391690f4f4683a43de8 350 SUPERFAMILY SSF55347 149 332 2.73E-40 T 23-10-2018 STK_12420 b0bd24f20ae6e391690f4f4683a43de8 350 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 130 3.5E-33 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 STK_12420 b0bd24f20ae6e391690f4f4683a43de8 350 TIGRFAM TIGR00978 asd_EA: aspartate-semialdehyde dehydrogenase 5 345 1.0E-158 T 23-10-2018 IPR005676 Aspartate-semialdehyde dehydrogenase, peptidoglycan lacking GO:0050661|GO:0055114 STK_12420 b0bd24f20ae6e391690f4f4683a43de8 350 PIRSF PIRSF000148 4 350 3.4E-92 T 23-10-2018 STK_12420 b0bd24f20ae6e391690f4f4683a43de8 350 SMART SM00859 6 132 9.4E-34 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 STK_12420 b0bd24f20ae6e391690f4f4683a43de8 350 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 160 330 1.2E-29 T 23-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 STK_12420 b0bd24f20ae6e391690f4f4683a43de8 350 Gene3D G3DSA:3.40.50.720 5 342 5.1E-139 T 23-10-2018 STK_12420 b0bd24f20ae6e391690f4f4683a43de8 350 Gene3D G3DSA:3.30.360.10 151 327 5.1E-139 T 23-10-2018 STK_12420 b0bd24f20ae6e391690f4f4683a43de8 350 SUPERFAMILY SSF51735 5 178 1.76E-42 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_05210 65e4d0ab7e8a8960e44749148695f50e 626 Pfam PF00482 Type II secretion system (T2SS), protein F 407 533 1.3E-11 T 23-10-2018 IPR018076 Type II secretion system F domain STK_05210 65e4d0ab7e8a8960e44749148695f50e 626 Pfam PF00482 Type II secretion system (T2SS), protein F 135 263 3.5E-7 T 23-10-2018 IPR018076 Type II secretion system F domain STK_11270 1335d648f0c6c565ed92dcb80a47f5ea 311 SUPERFAMILY SSF54909 2 308 9.31E-138 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel STK_11270 1335d648f0c6c565ed92dcb80a47f5ea 311 Pfam PF07682 Sulphur oxygenase reductase 4 303 2.9E-146 T 23-10-2018 IPR011661 Sulphur oxygenase reductase KEGG: 00920+1.13.11.55|MetaCyc: PWY-5302 STK_21060 7204402b9464b9fa3cddc38b6b081ac8 495 Pfam PF05872 Bacterial protein of unknown function (DUF853) 348 446 4.5E-7 T 23-10-2018 IPR033186 Helicase HerA-like C-terminal STK_21060 7204402b9464b9fa3cddc38b6b081ac8 495 Pfam PF09378 HAS barrel domain 3 86 1.4E-9 T 23-10-2018 IPR018538 Helicase HerA, barrel domain STK_21060 7204402b9464b9fa3cddc38b6b081ac8 495 Pfam PF01935 Domain of unknown function DUF87 120 330 4.2E-45 T 23-10-2018 IPR002789 Helicase HerA, central domain STK_21060 7204402b9464b9fa3cddc38b6b081ac8 495 SUPERFAMILY SSF52540 112 466 1.11E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_21060 7204402b9464b9fa3cddc38b6b081ac8 495 Gene3D G3DSA:3.40.50.300 107 274 2.0E-31 T 23-10-2018 STK_21060 7204402b9464b9fa3cddc38b6b081ac8 495 Gene3D G3DSA:3.40.50.300 275 475 1.4E-64 T 23-10-2018 STK_15300 02e26d8bed74a3b0a8c82d9dceb0aa2a 324 SUPERFAMILY SSF103473 2 321 3.01E-26 T 23-10-2018 IPR036259 MFS transporter superfamily STK_15300 02e26d8bed74a3b0a8c82d9dceb0aa2a 324 Pfam PF07690 Major Facilitator Superfamily 11 287 8.8E-18 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_15300 02e26d8bed74a3b0a8c82d9dceb0aa2a 324 Gene3D G3DSA:1.20.1250.20 1 320 5.0E-22 T 23-10-2018 STK_00620 7088b8a7534bb050eba5b97bf5d01211 510 Gene3D G3DSA:3.40.50.12780 1 404 9.3E-109 T 23-10-2018 STK_00620 7088b8a7534bb050eba5b97bf5d01211 510 SUPERFAMILY SSF56801 5 509 3.79E-132 T 23-10-2018 STK_00620 7088b8a7534bb050eba5b97bf5d01211 510 Gene3D G3DSA:3.30.300.310 405 510 1.1E-30 T 23-10-2018 STK_00620 7088b8a7534bb050eba5b97bf5d01211 510 Pfam PF13193 AMP-binding enzyme C-terminal domain 419 497 1.2E-17 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain STK_00620 7088b8a7534bb050eba5b97bf5d01211 510 ProSitePatterns PS00455 Putative AMP-binding domain signature. 158 169 - T 23-10-2018 IPR020845 AMP-binding, conserved site STK_00620 7088b8a7534bb050eba5b97bf5d01211 510 Pfam PF00501 AMP-binding enzyme 14 409 2.9E-95 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 STK_21550 2af0bd688c7f39056d9c517576a3cb03 222 SUPERFAMILY SSF54909 3 221 2.68E-62 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel STK_21550 2af0bd688c7f39056d9c517576a3cb03 222 Pfam PF06778 Chlorite dismutase 26 213 6.6E-49 T 23-10-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase STK_21550 2af0bd688c7f39056d9c517576a3cb03 222 Gene3D G3DSA:3.30.70.1100 107 221 1.2E-23 T 23-10-2018 STK_21190 0660ac2b2df4c2e38ae4d3e2c8a47380 164 Pfam PF00571 CBS domain 13 60 5.0E-13 T 23-10-2018 IPR000644 CBS domain STK_21190 0660ac2b2df4c2e38ae4d3e2c8a47380 164 Pfam PF00571 CBS domain 68 123 4.2E-17 T 23-10-2018 IPR000644 CBS domain STK_21190 0660ac2b2df4c2e38ae4d3e2c8a47380 164 SUPERFAMILY SSF54631 3 127 7.07E-36 T 23-10-2018 STK_21190 0660ac2b2df4c2e38ae4d3e2c8a47380 164 Gene3D G3DSA:3.10.580.10 3 157 7.9E-41 T 23-10-2018 STK_21190 0660ac2b2df4c2e38ae4d3e2c8a47380 164 SMART SM00116 12 60 9.4E-10 T 23-10-2018 IPR000644 CBS domain STK_21190 0660ac2b2df4c2e38ae4d3e2c8a47380 164 SMART SM00116 75 123 2.7E-13 T 23-10-2018 IPR000644 CBS domain STK_03070 fdca3a08adc754ed0e7c75bd30be0893 115 Pfam PF04434 SWIM zinc finger 33 73 7.5E-5 T 23-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 STK_01350 08f76e84338f0099a91e9904f9adee6e 172 SUPERFAMILY SSF49503 55 172 6.88E-16 T 23-10-2018 IPR008972 Cupredoxin STK_01350 08f76e84338f0099a91e9904f9adee6e 172 Gene3D G3DSA:2.60.40.420 63 171 9.4E-10 T 23-10-2018 IPR008972 Cupredoxin STK_07520 3144d0f9b4fa051ff03b9341620dd73d 530 Gene3D G3DSA:3.40.50.970 329 526 1.2E-43 T 23-10-2018 STK_07520 3144d0f9b4fa051ff03b9341620dd73d 530 SUPERFAMILY SSF52467 192 360 6.95E-31 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily STK_07520 3144d0f9b4fa051ff03b9341620dd73d 530 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 368 515 2.4E-33 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 STK_07520 3144d0f9b4fa051ff03b9341620dd73d 530 SUPERFAMILY SSF52518 345 524 6.53E-42 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold STK_07520 3144d0f9b4fa051ff03b9341620dd73d 530 Gene3D G3DSA:3.40.50.1220 191 328 2.5E-29 T 23-10-2018 STK_07520 3144d0f9b4fa051ff03b9341620dd73d 530 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 177 1.0E-45 T 23-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 STK_07520 3144d0f9b4fa051ff03b9341620dd73d 530 SUPERFAMILY SSF52518 8 179 1.67E-38 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold STK_07520 3144d0f9b4fa051ff03b9341620dd73d 530 Gene3D G3DSA:3.40.50.970 3 189 4.2E-44 T 23-10-2018 STK_07520 3144d0f9b4fa051ff03b9341620dd73d 530 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 198 320 6.6E-20 T 23-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 STK_12390 9424cbc5c4b4e13fbbdcf5e17d57cfa3 481 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 419 2.6E-124 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 STK_12390 9424cbc5c4b4e13fbbdcf5e17d57cfa3 481 SUPERFAMILY SSF143968 314 475 1.28E-55 T 23-10-2018 STK_12390 9424cbc5c4b4e13fbbdcf5e17d57cfa3 481 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 445 2.4E-122 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 STK_12390 9424cbc5c4b4e13fbbdcf5e17d57cfa3 481 Gene3D G3DSA:3.40.1670.10 328 444 9.3E-38 T 23-10-2018 STK_12390 9424cbc5c4b4e13fbbdcf5e17d57cfa3 481 SUPERFAMILY SSF50475 3 313 8.24E-89 T 23-10-2018 STK_09270 3fd4a0356062fd1daf435e7f3fb590fd 359 SUPERFAMILY SSF51445 7 286 1.74E-54 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily STK_09270 3fd4a0356062fd1daf435e7f3fb590fd 359 Gene3D G3DSA:2.60.40.1180 295 357 2.6E-5 T 23-10-2018 IPR013780 Glycosyl hydrolase, all-beta STK_09270 3fd4a0356062fd1daf435e7f3fb590fd 359 Gene3D G3DSA:3.20.20.80 1 241 2.3E-80 T 23-10-2018 STK_09270 3fd4a0356062fd1daf435e7f3fb590fd 359 Pfam PF09071 Alpha-amylase, C terminal 290 356 1.5E-34 T 23-10-2018 IPR015156 Malto-oligosyltrehalose trehalohydrolase, archaeal, C-terminal KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 STK_09270 3fd4a0356062fd1daf435e7f3fb590fd 359 Pfam PF00128 Alpha amylase, catalytic domain 27 222 2.7E-7 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 STK_09270 3fd4a0356062fd1daf435e7f3fb590fd 359 SUPERFAMILY SSF51011 290 356 1.08E-20 T 23-10-2018 STK_07010 4dc3f47292ac1f84b0ec9701e5a7436e 321 Pfam PF00005 ABC transporter 27 183 8.1E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_07010 4dc3f47292ac1f84b0ec9701e5a7436e 321 SUPERFAMILY SSF52540 34 318 2.18E-62 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_07010 4dc3f47292ac1f84b0ec9701e5a7436e 321 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 3.5E-34 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 STK_07010 4dc3f47292ac1f84b0ec9701e5a7436e 321 SMART SM00382 35 233 1.6E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_07010 4dc3f47292ac1f84b0ec9701e5a7436e 321 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 STK_07010 4dc3f47292ac1f84b0ec9701e5a7436e 321 Gene3D G3DSA:3.40.50.300 4 321 1.2E-97 T 23-10-2018 STK_07010 4dc3f47292ac1f84b0ec9701e5a7436e 321 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 2.6E-24 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 STK_06630 b7570822a56baf50d2ad428d7fd958ac 123 Gene3D G3DSA:1.20.120.330 2 123 1.7E-24 T 23-10-2018 STK_06630 b7570822a56baf50d2ad428d7fd958ac 123 SMART SM00748 6 116 9.1E-38 T 23-10-2018 IPR007842 HEPN domain STK_06630 b7570822a56baf50d2ad428d7fd958ac 123 Pfam PF05168 HEPN domain 2 120 1.6E-28 T 23-10-2018 IPR007842 HEPN domain STK_06630 b7570822a56baf50d2ad428d7fd958ac 123 SUPERFAMILY SSF81593 4 119 2.24E-25 T 23-10-2018 STK_00890 773fd3fb7075d5f43228f83f9dd03466 110 SUPERFAMILY SSF75169 2 110 1.0E-4 T 23-10-2018 IPR027396 DsrEFH-like STK_00890 773fd3fb7075d5f43228f83f9dd03466 110 Pfam PF02635 DsrE/DsrF-like family 3 110 1.9E-4 T 23-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein STK_00890 773fd3fb7075d5f43228f83f9dd03466 110 Gene3D G3DSA:3.40.1260.10 1 110 3.1E-17 T 23-10-2018 IPR027396 DsrEFH-like STK_26380 e82a9ad791a2c71bd3f4ca79ae2e22d7 241 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 6 44 8.3E-8 T 23-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal STK_26380 e82a9ad791a2c71bd3f4ca79ae2e22d7 241 Gene3D G3DSA:3.30.70.3120 2 241 8.9E-38 T 23-10-2018 STK_26380 e82a9ad791a2c71bd3f4ca79ae2e22d7 241 TIGRFAM TIGR01874 cas_cas5a: CRISPR-associated protein Cas5, subtype I-A/APERN 6 176 1.0E-70 T 23-10-2018 IPR010153 CRISPR-associated protein, Cas5a type STK_26380 e82a9ad791a2c71bd3f4ca79ae2e22d7 241 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 12 189 1.3E-7 T 23-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 STK_07240 06b325f3d4ee75cbe77836b72efaf982 316 TIGRFAM TIGR02295 HpaD: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 3 301 2.1E-117 T 23-10-2018 IPR011981 3,4-dihydroxyphenylacetate 2,3-dioxygenase, Mn/Fe-type STK_07240 06b325f3d4ee75cbe77836b72efaf982 316 SUPERFAMILY SSF54593 1 265 3.46E-44 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase STK_07240 06b325f3d4ee75cbe77836b72efaf982 316 ProSitePatterns PS00934 Glyoxalase I signature 1. 9 30 - T 23-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 STK_07240 06b325f3d4ee75cbe77836b72efaf982 316 Gene3D G3DSA:3.10.180.10 138 301 6.4E-34 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase STK_07240 06b325f3d4ee75cbe77836b72efaf982 316 Gene3D G3DSA:3.10.180.10 1 137 5.0E-43 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase STK_07240 06b325f3d4ee75cbe77836b72efaf982 316 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 111 8.8E-11 T 23-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain STK_07240 06b325f3d4ee75cbe77836b72efaf982 316 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 138 258 3.8E-10 T 23-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain STK_14785 c57c1f73380251709d40841fa8a22c11 195 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 166 174 - T 23-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 STK_00800 f990e117f8691a48bc52bcecbf4f212e 176 Gene3D G3DSA:1.10.12.20 33 103 8.8E-19 T 23-10-2018 STK_00800 f990e117f8691a48bc52bcecbf4f212e 176 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 63 94 2.0E-12 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal STK_00800 f990e117f8691a48bc52bcecbf4f212e 176 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 100 159 1.1E-12 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal STK_00800 f990e117f8691a48bc52bcecbf4f212e 176 SUPERFAMILY SSF50249 37 167 1.88E-36 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_00330 95552830de3c4780b56134f3a851cd07 212 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 13 187 1.1E-13 T 23-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain STK_00330 95552830de3c4780b56134f3a851cd07 212 Gene3D G3DSA:1.10.3210.30 1 179 2.7E-22 T 23-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily STK_00330 95552830de3c4780b56134f3a851cd07 212 SUPERFAMILY SSF109604 48 105 3.32E-6 T 23-10-2018 STK_03710 4d1085e095a2b2a6efc066b25247889a 246 Gene3D G3DSA:1.10.10.10 7 105 1.6E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_03710 4d1085e095a2b2a6efc066b25247889a 246 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 18 81 3.7E-17 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal STK_03710 4d1085e095a2b2a6efc066b25247889a 246 SUPERFAMILY SSF46785 9 100 7.55E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_25780 a580ce95b2922ee0867791269f0e9d80 156 Gene3D G3DSA:1.20.120.330 36 156 7.7E-38 T 23-10-2018 STK_25780 a580ce95b2922ee0867791269f0e9d80 156 Pfam PF05942 Archaeal PaREP1/PaREP8 family 36 147 1.1E-35 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_00371 97ff6502df8788a43a712a95d59470cb 108 SUPERFAMILY SSF81593 7 92 3.37E-6 T 23-10-2018 STK_00371 97ff6502df8788a43a712a95d59470cb 108 Gene3D G3DSA:1.20.120.330 2 108 7.3E-11 T 23-10-2018 STK_00371 97ff6502df8788a43a712a95d59470cb 108 Pfam PF05168 HEPN domain 5 103 4.8E-15 T 23-10-2018 IPR007842 HEPN domain STK_16225 fd10170c51d1b528284bd6b15f1c5dca 68 Gene3D G3DSA:3.10.20.30 1 68 3.0E-18 T 23-10-2018 IPR012675 Beta-grasp domain superfamily STK_16225 fd10170c51d1b528284bd6b15f1c5dca 68 Pfam PF02597 ThiS family 7 68 1.8E-8 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 STK_16225 fd10170c51d1b528284bd6b15f1c5dca 68 SUPERFAMILY SSF54285 5 68 1.19E-11 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp STK_11170 ff1b736a0c9b4df9d4e22c4e523253e8 533 Gene3D G3DSA:1.10.4160.10 24 515 5.3E-98 T 23-10-2018 IPR038271 Purine-cytosine permease superfamily STK_11170 ff1b736a0c9b4df9d4e22c4e523253e8 533 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 40 469 1.4E-64 T 23-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 STK_15430 99f44ab91b85834b75b4db537637914d 213 Pfam PF02223 Thymidylate kinase 9 201 1.1E-27 T 23-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 STK_15430 99f44ab91b85834b75b4db537637914d 213 Gene3D G3DSA:3.40.50.300 1 213 2.0E-68 T 23-10-2018 STK_15430 99f44ab91b85834b75b4db537637914d 213 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 200 8.7E-32 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 STK_15430 99f44ab91b85834b75b4db537637914d 213 Hamap MF_00165 Thymidylate kinase [tmk]. 5 209 18.485 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 STK_15430 99f44ab91b85834b75b4db537637914d 213 SUPERFAMILY SSF52540 1 211 6.8E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_21200 4df47dfe3b7e3c8d339c0c560d02da42 203 SUPERFAMILY SSF53254 1 188 6.55E-42 T 23-10-2018 IPR029033 Histidine phosphatase superfamily STK_21200 4df47dfe3b7e3c8d339c0c560d02da42 203 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 179 3.8E-37 T 23-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 STK_21200 4df47dfe3b7e3c8d339c0c560d02da42 203 Gene3D G3DSA:3.40.50.1240 1 193 2.6E-42 T 23-10-2018 IPR029033 Histidine phosphatase superfamily STK_21200 4df47dfe3b7e3c8d339c0c560d02da42 203 SMART SM00855 3 150 6.2E-15 T 23-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 STK_20990 1e64afaf88080200731082d64f9cc4bb 193 Gene3D G3DSA:3.40.50.1820 1 130 4.7E-31 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold STK_20990 1e64afaf88080200731082d64f9cc4bb 193 SUPERFAMILY SSF53474 3 191 2.63E-39 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold STK_20990 1e64afaf88080200731082d64f9cc4bb 193 Gene3D G3DSA:3.40.50.1820 131 191 3.7E-8 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold STK_20990 1e64afaf88080200731082d64f9cc4bb 193 Pfam PF00561 alpha/beta hydrolase fold 23 119 5.0E-12 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 STK_14010 a8e5ad240615f2772b3b43d437647b6b 224 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 199 212 6.5E-4 T 23-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 STK_14010 a8e5ad240615f2772b3b43d437647b6b 224 PIRSF PIRSF001435 4 223 3.7E-55 T 23-10-2018 STK_14010 a8e5ad240615f2772b3b43d437647b6b 224 SUPERFAMILY SSF48150 26 220 1.73E-54 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 STK_14010 a8e5ad240615f2772b3b43d437647b6b 224 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 199 215 - T 23-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 STK_14010 a8e5ad240615f2772b3b43d437647b6b 224 SMART SM00525 198 218 0.0081 T 23-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 STK_14010 a8e5ad240615f2772b3b43d437647b6b 224 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 39 172 1.4E-21 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 STK_14010 a8e5ad240615f2772b3b43d437647b6b 224 SMART SM00478 43 197 2.1E-37 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 STK_14010 a8e5ad240615f2772b3b43d437647b6b 224 Gene3D G3DSA:1.10.340.30 28 138 1.4E-26 T 23-10-2018 STK_14010 a8e5ad240615f2772b3b43d437647b6b 224 Gene3D G3DSA:1.10.1670.10 139 222 3.2E-21 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 STK_12030 13c885e808eb282154c2d680606a7000 122 Gene3D G3DSA:2.60.40.790 3 122 1.3E-9 T 23-10-2018 IPR008978 HSP20-like chaperone STK_12030 13c885e808eb282154c2d680606a7000 122 SUPERFAMILY SSF49764 42 121 3.14E-12 T 23-10-2018 IPR008978 HSP20-like chaperone STK_14510 7bb71145f3bad05c552c44e03cff1f60 278 Pfam PF01040 UbiA prenyltransferase family 19 262 4.3E-42 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 STK_14510 7bb71145f3bad05c552c44e03cff1f60 278 Gene3D G3DSA:1.10.357.140 9 156 2.2E-16 T 23-10-2018 STK_14510 7bb71145f3bad05c552c44e03cff1f60 278 Hamap MF_01286 Digeranylgeranylglyceryl phosphate synthase. 3 276 22.059 T 23-10-2018 IPR023547 Digeranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005886|GO:0008654|GO:0047295 KEGG: 00564+2.5.1.42|MetaCyc: PWY-6349 STK_14510 7bb71145f3bad05c552c44e03cff1f60 278 Gene3D G3DSA:1.20.120.1780 161 277 1.0E-5 T 23-10-2018 STK_10570 51446f2af396bfc564bd41ac20455664 268 Pfam PF04909 Amidohydrolase 70 267 4.0E-27 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 STK_10570 51446f2af396bfc564bd41ac20455664 268 SUPERFAMILY SSF51556 3 268 1.41E-41 T 23-10-2018 IPR032466 Metal-dependent hydrolase STK_10570 51446f2af396bfc564bd41ac20455664 268 Gene3D G3DSA:3.20.20.140 2 267 1.2E-37 T 23-10-2018 STK_11985 821869e19042a56a8332f441992212f1 48 Gene3D G3DSA:1.10.1220.10 1 47 1.4E-6 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 STK_11985 821869e19042a56a8332f441992212f1 48 SUPERFAMILY SSF47598 1 43 7.78E-7 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 STK_11985 821869e19042a56a8332f441992212f1 48 Pfam PF12651 Ribbon-helix-helix domain 4 41 3.1E-7 T 23-10-2018 IPR038733 Predicted DNA-binding protein, ribbon-helix-helix domain STK_06930 3b45219cbbc3c635b508d568f614eaf9 118 SUPERFAMILY SSF81593 5 116 1.49E-16 T 23-10-2018 STK_06930 3b45219cbbc3c635b508d568f614eaf9 118 Pfam PF05168 HEPN domain 1 116 2.7E-22 T 23-10-2018 IPR007842 HEPN domain STK_06930 3b45219cbbc3c635b508d568f614eaf9 118 SMART SM00748 5 113 0.0028 T 23-10-2018 IPR007842 HEPN domain STK_06930 3b45219cbbc3c635b508d568f614eaf9 118 Gene3D G3DSA:1.20.120.330 1 118 1.7E-13 T 23-10-2018 STK_21110 3285aa9bf14c3b55cb01df462cecefed 214 Gene3D G3DSA:3.40.50.150 7 201 1.8E-21 T 23-10-2018 STK_21110 3285aa9bf14c3b55cb01df462cecefed 214 SUPERFAMILY SSF53335 3 184 9.74E-15 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_21110 3285aa9bf14c3b55cb01df462cecefed 214 Pfam PF08241 Methyltransferase domain 37 116 4.6E-8 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 STK_07850 4977707262004ec7f044411202c768f4 134 SUPERFAMILY SSF81301 2 92 5.32E-12 T 23-10-2018 STK_07850 4977707262004ec7f044411202c768f4 134 Gene3D G3DSA:3.30.460.10 2 93 3.4E-10 T 23-10-2018 STK_07850 4977707262004ec7f044411202c768f4 134 Pfam PF01909 Nucleotidyltransferase domain 20 90 1.5E-4 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_15420 d38a5732aef55945d4826a16c04344ef 205 SUPERFAMILY SSF52540 2 203 2.63E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_15420 d38a5732aef55945d4826a16c04344ef 205 Pfam PF02223 Thymidylate kinase 5 195 1.3E-11 T 23-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 STK_15420 d38a5732aef55945d4826a16c04344ef 205 Gene3D G3DSA:3.40.50.300 1 204 1.2E-28 T 23-10-2018 STK_25080 44a983b3952793bfe1a34c34cdfc0692 186 SUPERFAMILY SSF52499 10 184 9.42E-43 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 STK_25080 44a983b3952793bfe1a34c34cdfc0692 186 Gene3D G3DSA:3.40.50.850 6 186 1.6E-36 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 STK_25080 44a983b3952793bfe1a34c34cdfc0692 186 Pfam PF00857 Isochorismatase family 18 172 1.5E-34 T 23-10-2018 IPR000868 Isochorismatase-like GO:0003824 STK_01370 e505e0bd6776f59e10765dd3ea91858a 566 SUPERFAMILY SSF81648 222 398 2.13E-16 T 23-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 STK_01370 e505e0bd6776f59e10765dd3ea91858a 566 Gene3D G3DSA:1.20.810.10 6 439 2.0E-72 T 23-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 STK_01370 e505e0bd6776f59e10765dd3ea91858a 566 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 100 300 1.3E-55 T 23-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 STK_01370 e505e0bd6776f59e10765dd3ea91858a 566 SUPERFAMILY SSF81342 19 276 1.4E-47 T 23-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 STK_03120 714940d496a104a900f8e0fd5bf235ab 303 Pfam PF08489 Domain of unknown function (DUF1743) 6 120 8.0E-36 T 23-10-2018 IPR013696 Domain of unknown function DUF1743 STK_03120 714940d496a104a900f8e0fd5bf235ab 303 Gene3D G3DSA:3.90.600.20 22 117 1.5E-30 T 23-10-2018 STK_03120 714940d496a104a900f8e0fd5bf235ab 303 Gene3D G3DSA:2.40.50.1010 118 262 8.8E-32 T 23-10-2018 STK_02960 5cdfec4a99fc9098db0f1e0c80f80371 171 Gene3D G3DSA:3.30.428.10 1 168 1.8E-55 T 23-10-2018 IPR036265 HIT-like superfamily STK_02960 5cdfec4a99fc9098db0f1e0c80f80371 171 Pfam PF01230 HIT domain 38 128 2.1E-13 T 23-10-2018 IPR001310 Histidine triad (HIT) protein STK_02960 5cdfec4a99fc9098db0f1e0c80f80371 171 SUPERFAMILY SSF54197 1 156 4.33E-44 T 23-10-2018 IPR036265 HIT-like superfamily STK_14525 d4a4fdd25b0fce8be7934a7fd215ff9f 93 Pfam PF02680 Uncharacterized ArCR, COG1888 3 89 6.5E-37 T 23-10-2018 IPR003831 Protein of unknown function DUF211 STK_14525 d4a4fdd25b0fce8be7934a7fd215ff9f 93 Gene3D G3DSA:3.30.70.1340 1 86 1.6E-34 T 23-10-2018 IPR023129 MTH889-like domain superfamily STK_14525 d4a4fdd25b0fce8be7934a7fd215ff9f 93 SUPERFAMILY SSF160363 2 91 2.49E-33 T 23-10-2018 IPR023129 MTH889-like domain superfamily STK_14525 d4a4fdd25b0fce8be7934a7fd215ff9f 93 ProDom PD012512 ARCHAEA PH1931 STS176 TA1183 MJ0319 PRECURSOR TVG0378908 UNCHARACTERIZED DUF211 AF1549 10 88 3.0E-37 T 23-10-2018 IPR003831 Protein of unknown function DUF211 STK_11040 bd455abc5f7243b385e4babb04947874 292 SUPERFAMILY SSF161098 51 280 1.57E-56 T 23-10-2018 IPR035906 MetI-like superfamily STK_11040 bd455abc5f7243b385e4babb04947874 292 SUPERFAMILY SSF160964 4 47 1.19E-6 T 23-10-2018 STK_11040 bd455abc5f7243b385e4babb04947874 292 Gene3D G3DSA:1.10.3720.10 47 288 7.9E-63 T 23-10-2018 IPR035906 MetI-like superfamily STK_11040 bd455abc5f7243b385e4babb04947874 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 285 1.3E-14 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 STK_02210 846f259ba8f463fd526384b1ef31a72b 367 Gene3D G3DSA:3.50.50.60 2 341 8.8E-64 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_02210 846f259ba8f463fd526384b1ef31a72b 367 Pfam PF01266 FAD dependent oxidoreductase 2 337 1.6E-43 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 STK_02210 846f259ba8f463fd526384b1ef31a72b 367 Gene3D G3DSA:3.30.9.10 81 296 8.8E-64 T 23-10-2018 STK_02210 846f259ba8f463fd526384b1ef31a72b 367 SUPERFAMILY SSF51905 2 358 3.95E-36 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_03690 c108b3d948c74c18e5234e95676fabd5 109 ProDom PD289296 ST0369 SSO0428 1 109 1.0E-53 T 23-10-2018 IPR020330 Uncharacterised protein family SSO0428 STK_11100 4003374d918a31e99f29dff0db8956c5 386 Gene3D G3DSA:3.40.47.10 1 383 3.0E-66 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_11100 4003374d918a31e99f29dff0db8956c5 386 SUPERFAMILY SSF53901 262 371 5.87E-14 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_11100 4003374d918a31e99f29dff0db8956c5 386 SUPERFAMILY SSF53901 15 208 1.67E-13 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_23600 3ee7c22f471200040b331fc6706c240a 473 Gene3D G3DSA:1.20.1740.10 5 440 1.1E-21 T 23-10-2018 STK_23600 3ee7c22f471200040b331fc6706c240a 473 Pfam PF13520 Amino acid permease 17 384 3.3E-17 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_23600 3ee7c22f471200040b331fc6706c240a 473 PIRSF PIRSF006060 1 463 1.6E-48 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_12070 8512cf0c0954742f9f635727d0457ef7 449 Gene3D G3DSA:3.40.640.10 85 355 1.2E-149 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 STK_12070 8512cf0c0954742f9f635727d0457ef7 449 Pfam PF02347 Glycine cleavage system P-protein 14 441 1.8E-118 T 23-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 STK_12070 8512cf0c0954742f9f635727d0457ef7 449 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 4 446 48.923 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 STK_12070 8512cf0c0954742f9f635727d0457ef7 449 PIRSF PIRSF006815 4 447 9.0E-158 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 STK_12070 8512cf0c0954742f9f635727d0457ef7 449 Gene3D G3DSA:3.90.1150.10 74 442 1.2E-149 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 STK_12070 8512cf0c0954742f9f635727d0457ef7 449 SUPERFAMILY SSF53383 8 446 1.22E-99 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase STK_01820 26f02af5cdf0fe66d389bb2745f67fda 211 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 11 202 5.9E-40 T 23-10-2018 STK_01820 26f02af5cdf0fe66d389bb2745f67fda 211 Gene3D G3DSA:3.40.50.150 3 209 6.6E-51 T 23-10-2018 STK_01820 26f02af5cdf0fe66d389bb2745f67fda 211 SUPERFAMILY SSF53335 11 201 3.68E-35 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_14700 1253bd57fbc9d609e43e53ed344e5a28 489 Gene3D G3DSA:3.80.30.20 203 410 2.6E-24 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe STK_14700 1253bd57fbc9d609e43e53ed344e5a28 489 Pfam PF04055 Radical SAM superfamily 207 393 6.1E-16 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_14700 1253bd57fbc9d609e43e53ed344e5a28 489 SMART SM00729 203 428 1.9E-25 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 STK_14700 1253bd57fbc9d609e43e53ed344e5a28 489 SUPERFAMILY SSF102114 203 439 2.09E-17 T 23-10-2018 STK_20620 848b4ef2af33435a710c93c37323eebc 284 Gene3D G3DSA:3.40.830.10 1 282 1.0E-68 T 23-10-2018 STK_20620 848b4ef2af33435a710c93c37323eebc 284 Pfam PF01875 Memo-like protein 5 280 8.5E-88 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 STK_20620 848b4ef2af33435a710c93c37323eebc 284 Hamap MF_00055 MEMO1 family protein . 1 283 62.742 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 STK_20620 848b4ef2af33435a710c93c37323eebc 284 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 3 281 5.3E-100 T 23-10-2018 STK_18280 52f4a816143bbf5fa97f0ac784bd9086 401 SUPERFAMILY SSF103473 4 394 3.01E-45 T 23-10-2018 IPR036259 MFS transporter superfamily STK_18280 52f4a816143bbf5fa97f0ac784bd9086 401 Pfam PF07690 Major Facilitator Superfamily 37 340 7.8E-18 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_18280 52f4a816143bbf5fa97f0ac784bd9086 401 Gene3D G3DSA:1.20.1250.20 7 401 1.1E-51 T 23-10-2018 STK_18280 52f4a816143bbf5fa97f0ac784bd9086 401 ProSitePatterns PS00216 Sugar transport proteins signature 1. 269 286 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 STK_14340 5b44dd10c596713eb78b8fecc6513252 100 Gene3D G3DSA:3.40.50.10580 4 99 1.4E-18 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 STK_14340 5b44dd10c596713eb78b8fecc6513252 100 Pfam PF01990 ATP synthase (F/14-kDa) subunit 4 85 1.2E-15 T 23-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 STK_14340 5b44dd10c596713eb78b8fecc6513252 100 SUPERFAMILY SSF159468 4 99 3.53E-20 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 STK_03100 dfeaf9c7d788a19b8d487e27a1fb21c5 244 Pfam PF01884 PcrB family 13 238 5.6E-55 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 STK_03100 dfeaf9c7d788a19b8d487e27a1fb21c5 244 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 10 239 32.529 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 STK_03100 dfeaf9c7d788a19b8d487e27a1fb21c5 244 SUPERFAMILY SSF51395 10 236 7.32E-40 T 23-10-2018 STK_03100 dfeaf9c7d788a19b8d487e27a1fb21c5 244 TIGRFAM TIGR01769 GGGP: phosphoglycerol geranylgeranyltransferase 16 222 6.5E-79 T 23-10-2018 IPR010946 Geranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005737|GO:0006650|GO:0047294 KEGG: 00564+2.5.1.41|MetaCyc: PWY-6349 STK_03100 dfeaf9c7d788a19b8d487e27a1fb21c5 244 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 15 237 1.2E-83 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 STK_03100 dfeaf9c7d788a19b8d487e27a1fb21c5 244 Gene3D G3DSA:3.20.20.390 1 243 4.7E-78 T 23-10-2018 IPR038597 GGGP/HepGP synthase superfamily STK_17887 da34150cff04eed7ef39f8decd99be7c 184 Gene3D G3DSA:3.40.920.10 1 179 2.8E-53 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 STK_17887 da34150cff04eed7ef39f8decd99be7c 184 SUPERFAMILY SSF53323 2 176 1.96E-46 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 STK_17887 da34150cff04eed7ef39f8decd99be7c 184 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 1 177 2.8E-63 T 23-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 STK_17887 da34150cff04eed7ef39f8decd99be7c 184 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 10 174 7.5E-37 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 STK_05830 be13a0af5773e2761d4b817ad591af75 324 Gene3D G3DSA:3.10.310.30 237 289 1.3E-7 T 23-10-2018 STK_05830 be13a0af5773e2761d4b817ad591af75 324 SUPERFAMILY SSF64182 6 289 1.09E-23 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily STK_05830 be13a0af5773e2761d4b817ad591af75 324 Pfam PF02272 DHHA1 domain 192 281 1.7E-8 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 STK_03225 6e38aede4f99c4d513d6530c0943a445 92 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 35 81 1.5E-7 T 23-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 STK_03225 6e38aede4f99c4d513d6530c0943a445 92 Gene3D G3DSA:3.40.1350.10 4 92 2.3E-12 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 STK_03225 6e38aede4f99c4d513d6530c0943a445 92 SUPERFAMILY SSF53032 5 89 7.33E-17 T 23-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 STK_25700 63372390f398851adf0be25a79a0554f 201 Gene3D G3DSA:1.10.150.240 18 71 9.4E-69 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 STK_25700 63372390f398851adf0be25a79a0554f 201 Gene3D G3DSA:3.40.50.1000 72 192 9.4E-69 T 23-10-2018 IPR023214 HAD superfamily STK_25700 63372390f398851adf0be25a79a0554f 201 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 169 3.1E-15 T 23-10-2018 STK_25700 63372390f398851adf0be25a79a0554f 201 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 3 173 5.4E-44 T 23-10-2018 IPR006328 L-2-Haloacid dehalogenase GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 STK_25700 63372390f398851adf0be25a79a0554f 201 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 5 163 2.8E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 STK_25700 63372390f398851adf0be25a79a0554f 201 SUPERFAMILY SSF56784 4 197 7.27E-34 T 23-10-2018 IPR036412 HAD-like superfamily STK_25700 63372390f398851adf0be25a79a0554f 201 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 1.2E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 STK_25700 63372390f398851adf0be25a79a0554f 201 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 115 131 1.2E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 STK_25700 63372390f398851adf0be25a79a0554f 201 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 158 171 1.2E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 STK_25700 63372390f398851adf0be25a79a0554f 201 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 16 161 9.2E-13 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 STK_13173 86726c3847ddf21acb481f38d1a9ec0d 158 Pfam PF02661 Fic/DOC family 61 102 3.6E-6 T 23-10-2018 IPR003812 Fido domain STK_13173 86726c3847ddf21acb481f38d1a9ec0d 158 SUPERFAMILY SSF140931 27 108 7.19E-8 T 23-10-2018 IPR036597 Fido-like domain superfamily STK_13173 86726c3847ddf21acb481f38d1a9ec0d 158 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 30 146 3.0E-24 T 23-10-2018 IPR006440 Death on curing protein GO:0016301 STK_13173 86726c3847ddf21acb481f38d1a9ec0d 158 Gene3D G3DSA:1.20.120.1870 27 152 4.0E-9 T 23-10-2018 STK_22215 ef151099907aaed5c71a77f4e1e9e526 94 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 9 94 1.6E-9 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like STK_21090 4a352ed304c1bd78c6ecd4bde5e8165f 331 Pfam PF09376 NurA domain 51 304 4.0E-39 T 23-10-2018 IPR018977 NurA domain STK_21090 4a352ed304c1bd78c6ecd4bde5e8165f 331 SMART SM00933 50 304 9.5E-50 T 23-10-2018 IPR018977 NurA domain STK_09530 84bd3f9bdc10e7a65b870a452e5c2098 199 Gene3D G3DSA:3.30.200.20 38 100 2.9E-5 T 23-10-2018 STK_09530 84bd3f9bdc10e7a65b870a452e5c2098 199 SUPERFAMILY SSF56112 36 163 1.26E-13 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily STK_09530 84bd3f9bdc10e7a65b870a452e5c2098 199 Gene3D G3DSA:1.10.510.10 101 155 2.9E-5 T 23-10-2018 STK_14860 846551e487f9aeaa3dc7a1a7d18a108a 102 SUPERFAMILY SSF46785 24 83 9.47E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_14860 846551e487f9aeaa3dc7a1a7d18a108a 102 Pfam PF01022 Bacterial regulatory protein, arsR family 25 69 5.7E-11 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 STK_14860 846551e487f9aeaa3dc7a1a7d18a108a 102 Gene3D G3DSA:1.10.10.10 1 101 4.4E-16 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_14860 846551e487f9aeaa3dc7a1a7d18a108a 102 SMART SM00418 16 92 0.0018 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 STK_17460 dbbe8f37dae2067c54fb2dbe2382da4c 786 Pfam PF11838 ERAP1-like C-terminal domain 484 773 1.6E-23 T 23-10-2018 IPR024571 ERAP1-like C-terminal domain STK_17460 dbbe8f37dae2067c54fb2dbe2382da4c 786 SUPERFAMILY SSF55486 182 427 4.54E-84 T 23-10-2018 STK_17460 dbbe8f37dae2067c54fb2dbe2382da4c 786 Gene3D G3DSA:1.25.50.20 506 783 1.0E-16 T 23-10-2018 STK_17460 dbbe8f37dae2067c54fb2dbe2382da4c 786 Gene3D G3DSA:2.60.40.1730 2 173 1.6E-41 T 23-10-2018 STK_17460 dbbe8f37dae2067c54fb2dbe2382da4c 786 SUPERFAMILY SSF63737 7 172 3.27E-38 T 23-10-2018 STK_17460 dbbe8f37dae2067c54fb2dbe2382da4c 786 Gene3D G3DSA:1.10.390.60 177 420 2.7E-98 T 23-10-2018 STK_17460 dbbe8f37dae2067c54fb2dbe2382da4c 786 Pfam PF01433 Peptidase family M1 domain 189 415 3.0E-85 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 STK_17460 dbbe8f37dae2067c54fb2dbe2382da4c 786 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 267 282 3.1E-27 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 STK_17460 dbbe8f37dae2067c54fb2dbe2382da4c 786 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 286 298 3.1E-27 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 STK_17460 dbbe8f37dae2067c54fb2dbe2382da4c 786 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 232 242 3.1E-27 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 STK_17460 dbbe8f37dae2067c54fb2dbe2382da4c 786 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 155 170 3.1E-27 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 STK_17460 dbbe8f37dae2067c54fb2dbe2382da4c 786 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 108 123 3.1E-27 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 STK_17460 dbbe8f37dae2067c54fb2dbe2382da4c 786 Gene3D G3DSA:2.60.40.1910 421 498 1.3E-16 T 23-10-2018 STK_00790 96cca12739c32d5f22f4d64ebcb88c07 397 SUPERFAMILY SSF53901 234 374 2.76E-25 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_00790 96cca12739c32d5f22f4d64ebcb88c07 397 SUPERFAMILY SSF53901 5 229 6.36E-49 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_00790 96cca12739c32d5f22f4d64ebcb88c07 397 PIRSF PIRSF000429 1 390 9.8E-68 T 23-10-2018 IPR002155 Thiolase GO:0016747 STK_00790 96cca12739c32d5f22f4d64ebcb88c07 397 Gene3D G3DSA:3.40.47.10 5 393 3.0E-122 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 STK_00790 96cca12739c32d5f22f4d64ebcb88c07 397 Pfam PF02803 Thiolase, C-terminal domain 263 360 7.2E-7 T 23-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 STK_00790 96cca12739c32d5f22f4d64ebcb88c07 397 Pfam PF00108 Thiolase, N-terminal domain 6 225 5.0E-30 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 STK_19660 d67d565042186cf5954d6186291baad3 345 Pfam PF00534 Glycosyl transferases group 1 230 325 2.9E-14 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 STK_19660 d67d565042186cf5954d6186291baad3 345 SUPERFAMILY SSF53756 10 342 8.37E-33 T 23-10-2018 STK_19660 d67d565042186cf5954d6186291baad3 345 Gene3D G3DSA:3.40.50.2000 176 331 3.4E-20 T 23-10-2018 STK_04560 5e2f65fd86e60f0a619855915bb84ff4 220 SMART SM00650 13 158 7.5E-26 T 23-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 STK_04560 5e2f65fd86e60f0a619855915bb84ff4 220 Gene3D G3DSA:1.10.8.100 113 193 8.7E-27 T 23-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 STK_04560 5e2f65fd86e60f0a619855915bb84ff4 220 Gene3D G3DSA:3.40.50.150 5 158 8.7E-27 T 23-10-2018 STK_04560 5e2f65fd86e60f0a619855915bb84ff4 220 SUPERFAMILY SSF53335 5 216 3.32E-25 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_04560 5e2f65fd86e60f0a619855915bb84ff4 220 Pfam PF00398 Ribosomal RNA adenine dimethylase 76 181 1.4E-8 T 23-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm STK_04560 5e2f65fd86e60f0a619855915bb84ff4 220 Pfam PF00398 Ribosomal RNA adenine dimethylase 3 62 9.9E-7 T 23-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm STK_22830 65475f8c1083f9960bd6e7864f5b5ede 211 Gene3D G3DSA:1.10.287.990 27 93 3.0E-25 T 23-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 STK_22830 65475f8c1083f9960bd6e7864f5b5ede 211 SUPERFAMILY SSF54719 96 209 3.01E-39 T 23-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 STK_22830 65475f8c1083f9960bd6e7864f5b5ede 211 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 102 203 1.0E-32 T 23-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 STK_22830 65475f8c1083f9960bd6e7864f5b5ede 211 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 171 178 - T 23-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 STK_22830 65475f8c1083f9960bd6e7864f5b5ede 211 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 9 93 1.9E-28 T 23-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 STK_22830 65475f8c1083f9960bd6e7864f5b5ede 211 PRINTS PR01703 Manganese superoxide dismutase signature 169 181 1.7E-15 T 23-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 STK_22830 65475f8c1083f9960bd6e7864f5b5ede 211 PRINTS PR01703 Manganese superoxide dismutase signature 131 139 1.7E-15 T 23-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 STK_22830 65475f8c1083f9960bd6e7864f5b5ede 211 PRINTS PR01703 Manganese superoxide dismutase signature 76 89 1.7E-15 T 23-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 STK_22830 65475f8c1083f9960bd6e7864f5b5ede 211 PRINTS PR01703 Manganese superoxide dismutase signature 13 24 1.7E-15 T 23-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 STK_22830 65475f8c1083f9960bd6e7864f5b5ede 211 PRINTS PR01703 Manganese superoxide dismutase signature 34 47 1.7E-15 T 23-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 STK_22830 65475f8c1083f9960bd6e7864f5b5ede 211 Gene3D G3DSA:2.40.500.20 94 211 1.4E-44 T 23-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 STK_22830 65475f8c1083f9960bd6e7864f5b5ede 211 PIRSF PIRSF000349 1 211 4.2E-72 T 23-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 STK_22830 65475f8c1083f9960bd6e7864f5b5ede 211 SUPERFAMILY SSF46609 7 93 2.09E-27 T 23-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 STK_17570 4b597896711a75ade5acb0327a701ff0 507 Pfam PF13520 Amino acid permease 12 466 1.8E-26 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_17570 4b597896711a75ade5acb0327a701ff0 507 PIRSF PIRSF006060 454 505 170.0 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_17570 4b597896711a75ade5acb0327a701ff0 507 PIRSF PIRSF006060 1 474 2.8E-50 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_17570 4b597896711a75ade5acb0327a701ff0 507 Gene3D G3DSA:1.20.1740.10 7 459 9.1E-45 T 23-10-2018 STK_24910 2b83d1cf1fef3dbb15008c7a19e15b62 272 Gene3D G3DSA:3.40.50.300 1 199 1.0E-47 T 23-10-2018 STK_24910 2b83d1cf1fef3dbb15008c7a19e15b62 272 Pfam PF01637 ATPase domain predominantly from Archaea 5 239 1.2E-24 T 23-10-2018 IPR011579 ATPase domain GO:0005524 STK_24910 2b83d1cf1fef3dbb15008c7a19e15b62 272 Gene3D G3DSA:1.10.8.60 200 271 1.4E-21 T 23-10-2018 STK_24910 2b83d1cf1fef3dbb15008c7a19e15b62 272 SUPERFAMILY SSF52540 2 264 2.81E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_03830 f7ba995d899b71e8d5c4e6feb560a1e9 120 SUPERFAMILY SSF53800 1 114 1.44E-29 T 23-10-2018 STK_03830 f7ba995d899b71e8d5c4e6feb560a1e9 120 Hamap MF_00785 Sirohydrochlorin cobaltochelatase [cbiX]. 1 113 28.249 T 23-10-2018 IPR023652 Sirohydrochlorin cobaltochelatase GO:0016852|GO:0050897 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 STK_03830 f7ba995d899b71e8d5c4e6feb560a1e9 120 Gene3D G3DSA:3.40.50.1400 2 118 3.5E-32 T 23-10-2018 STK_03830 f7ba995d899b71e8d5c4e6feb560a1e9 120 Pfam PF01903 CbiX 9 108 9.8E-26 T 23-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 STK_02560 3f1916602e77ec3cad65abae89c11977 149 Pfam PF01381 Helix-turn-helix 18 65 1.7E-6 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 STK_02560 3f1916602e77ec3cad65abae89c11977 149 SMART SM00530 17 69 0.0013 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 STK_00520 3ce2448dc4910749c057e52272c8165e 478 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 7 415 2.3E-106 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 STK_00520 3ce2448dc4910749c057e52272c8165e 478 SUPERFAMILY SSF50475 3 305 2.2E-76 T 23-10-2018 STK_00520 3ce2448dc4910749c057e52272c8165e 478 Gene3D G3DSA:3.40.1670.10 325 442 3.6E-28 T 23-10-2018 STK_00520 3ce2448dc4910749c057e52272c8165e 478 SUPERFAMILY SSF143968 309 476 2.48E-39 T 23-10-2018 STK_00520 3ce2448dc4910749c057e52272c8165e 478 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 4 430 1.5E-83 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 STK_15480 14f4c914950e269003ad52098adaad9f 194 Gene3D G3DSA:3.60.15.10 1 192 1.5E-40 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_15480 14f4c914950e269003ad52098adaad9f 194 SMART SM00849 19 181 1.8E-17 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_15480 14f4c914950e269003ad52098adaad9f 194 Pfam PF00753 Metallo-beta-lactamase superfamily 2 181 7.6E-25 T 23-10-2018 IPR001279 Metallo-beta-lactamase STK_15480 14f4c914950e269003ad52098adaad9f 194 SUPERFAMILY SSF56281 2 186 3.41E-36 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_17610 a731473dba1c19ff6a11696a1d62f193 292 Pfam PF07788 PD-(D/E)XK nuclease superfamily 210 283 4.2E-31 T 23-10-2018 IPR012431 PD-(D/E)XK nuclease STK_17610 a731473dba1c19ff6a11696a1d62f193 292 Pfam PF12644 Protein of unknown function (DUF3782) 133 209 1.5E-21 T 23-10-2018 IPR024271 Protein of unknown function DUF3782 STK_14680 351c1d8b78e9eb2ddc0f0e87a0f0c55e 135 Pfam PF01883 Iron-sulfur cluster assembly protein 13 85 2.7E-20 T 23-10-2018 IPR002744 MIP18 family-like STK_14680 351c1d8b78e9eb2ddc0f0e87a0f0c55e 135 Gene3D G3DSA:3.30.300.130 4 108 2.9E-31 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily STK_14680 351c1d8b78e9eb2ddc0f0e87a0f0c55e 135 SUPERFAMILY SSF117916 11 106 4.8E-27 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily STK_20080 4379af46acd80f9af620856c02498407 382 Pfam PF07282 Putative transposase DNA-binding domain 297 364 3.9E-22 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_20080 4379af46acd80f9af620856c02498407 382 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 243 324 3.2E-24 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_19640 ba260c905bd94f606741af7381a8e4b3 215 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 39 173 1.7E-28 T 23-10-2018 IPR006342 Methyltransferase FkbM STK_19640 ba260c905bd94f606741af7381a8e4b3 215 Gene3D G3DSA:3.40.50.150 27 199 1.6E-23 T 23-10-2018 STK_19640 ba260c905bd94f606741af7381a8e4b3 215 Pfam PF05050 Methyltransferase FkbM domain 42 190 1.5E-12 T 23-10-2018 IPR006342 Methyltransferase FkbM STK_19640 ba260c905bd94f606741af7381a8e4b3 215 SUPERFAMILY SSF53335 15 193 5.05E-32 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_11480 cc1921c00571912956afe27719ddbd46 367 Gene3D G3DSA:1.10.630.10 1 367 2.1E-99 T 23-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 STK_11480 cc1921c00571912956afe27719ddbd46 367 SUPERFAMILY SSF48264 4 365 2.62E-64 T 23-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 STK_11480 cc1921c00571912956afe27719ddbd46 367 PRINTS PR00359 B-class P450 signature 259 286 2.7E-35 T 23-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 STK_11480 cc1921c00571912956afe27719ddbd46 367 PRINTS PR00359 B-class P450 signature 317 328 2.7E-35 T 23-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 STK_11480 cc1921c00571912956afe27719ddbd46 367 PRINTS PR00359 B-class P450 signature 287 302 2.7E-35 T 23-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 STK_11480 cc1921c00571912956afe27719ddbd46 367 PRINTS PR00359 B-class P450 signature 242 253 2.7E-35 T 23-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 STK_11480 cc1921c00571912956afe27719ddbd46 367 PRINTS PR00359 B-class P450 signature 308 317 2.7E-35 T 23-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 STK_11480 cc1921c00571912956afe27719ddbd46 367 PRINTS PR00359 B-class P450 signature 71 82 2.7E-35 T 23-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 STK_11480 cc1921c00571912956afe27719ddbd46 367 PRINTS PR00359 B-class P450 signature 113 129 2.7E-35 T 23-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 STK_11480 cc1921c00571912956afe27719ddbd46 367 Pfam PF00067 Cytochrome P450 243 352 1.3E-21 T 23-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 STK_11480 cc1921c00571912956afe27719ddbd46 367 PRINTS PR00385 P450 superfamily signature 210 227 4.0E-5 T 23-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 STK_11480 cc1921c00571912956afe27719ddbd46 367 PRINTS PR00385 P450 superfamily signature 242 253 4.0E-5 T 23-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 STK_11480 cc1921c00571912956afe27719ddbd46 367 PRINTS PR00385 P450 superfamily signature 317 328 4.0E-5 T 23-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 STK_11480 cc1921c00571912956afe27719ddbd46 367 PRINTS PR00385 P450 superfamily signature 308 317 4.0E-5 T 23-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 STK_11480 cc1921c00571912956afe27719ddbd46 367 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 310 319 - T 23-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 STK_10950 a704ad8af63fa2ec317d828488262725 157 Gene3D G3DSA:3.90.420.10 2 154 1.0E-44 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 STK_10950 a704ad8af63fa2ec317d828488262725 157 SUPERFAMILY SSF56524 5 143 2.75E-46 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 STK_10950 a704ad8af63fa2ec317d828488262725 157 Pfam PF00174 Oxidoreductase molybdopterin binding domain 6 138 1.9E-35 T 23-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 STK_05350 480ff428a0b2b296457e3115377769c8 244 SMART SM00382 31 230 3.7E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_05350 480ff428a0b2b296457e3115377769c8 244 Gene3D G3DSA:3.40.50.300 1 244 5.7E-59 T 23-10-2018 STK_05350 480ff428a0b2b296457e3115377769c8 244 SUPERFAMILY SSF52540 5 229 2.5E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_05350 480ff428a0b2b296457e3115377769c8 244 Pfam PF00005 ABC transporter 22 165 1.1E-25 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_19740 754292591b7be05caa0c38bcf34a6cbe 284 TIGRFAM TIGR02580 cas_RAMP_Cmr4: CRISPR type III-B/RAMP module RAMP protein Cmr4 9 277 4.5E-89 T 23-10-2018 IPR013410 CRISPR-associated RAMP Cmr4 STK_19740 754292591b7be05caa0c38bcf34a6cbe 284 Pfam PF03787 RAMP superfamily 15 277 1.7E-27 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein STK_06260 832e4a5aa416914afbb2637973ad05c6 350 Gene3D G3DSA:3.20.20.70 2 328 4.5E-42 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_06260 832e4a5aa416914afbb2637973ad05c6 350 Pfam PF04055 Radical SAM superfamily 7 142 1.1E-10 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_06260 832e4a5aa416914afbb2637973ad05c6 350 TIGRFAM TIGR04084 rSAM_AF0577: putative peptide-modifying radical SAM enzyme, AF0577 family 5 350 4.1E-194 T 23-10-2018 IPR023819 Peptide-modifying radical SAM enzyme putative, AF0577 STK_06260 832e4a5aa416914afbb2637973ad05c6 350 Pfam PF13353 4Fe-4S single cluster domain 5 113 9.9E-8 T 23-10-2018 STK_06260 832e4a5aa416914afbb2637973ad05c6 350 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 229 295 1.3E-8 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain STK_06260 832e4a5aa416914afbb2637973ad05c6 350 SUPERFAMILY SSF102114 5 288 2.35E-37 T 23-10-2018 STK_17800 9afdd1531e643cd8c6f1255469625965 246 SUPERFAMILY SSF159941 42 206 1.31E-24 T 23-10-2018 IPR024047 MM3350-like superfamily STK_17800 9afdd1531e643cd8c6f1255469625965 246 Gene3D G3DSA:3.10.290.30 39 209 2.1E-9 T 23-10-2018 IPR024047 MM3350-like superfamily STK_17800 9afdd1531e643cd8c6f1255469625965 246 Pfam PF07929 Plasmid pRiA4b ORF-3-like protein 51 165 8.6E-11 T 23-10-2018 IPR012912 Plasmid pRiA4b, Orf3 STK_00540 de5b23b18af9d44819d9d63532919325 442 SUPERFAMILY SSF103473 10 436 9.94E-53 T 23-10-2018 IPR036259 MFS transporter superfamily STK_00540 de5b23b18af9d44819d9d63532919325 442 Pfam PF07690 Major Facilitator Superfamily 57 384 9.3E-21 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_00540 de5b23b18af9d44819d9d63532919325 442 Gene3D G3DSA:1.20.1250.20 11 440 7.5E-51 T 23-10-2018 STK_00460 7d992510ac7ea84109a821dfcf043a6c 321 Pfam PF03400 IS1 transposase 177 287 8.6E-12 T 23-10-2018 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 STK_03200 0488ead2757ec114ecadaeacd51de60b 540 Pfam PF01935 Domain of unknown function DUF87 209 411 1.1E-36 T 23-10-2018 IPR002789 Helicase HerA, central domain STK_03200 0488ead2757ec114ecadaeacd51de60b 540 Gene3D G3DSA:3.40.50.300 370 540 1.9E-28 T 23-10-2018 STK_03200 0488ead2757ec114ecadaeacd51de60b 540 Gene3D G3DSA:3.40.50.300 197 339 1.2E-22 T 23-10-2018 STK_03200 0488ead2757ec114ecadaeacd51de60b 540 SUPERFAMILY SSF52540 175 537 1.0E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_11430 cfde47db4a5f139edecc553a92645472 396 SUPERFAMILY SSF52540 43 216 6.51E-18 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_11430 cfde47db4a5f139edecc553a92645472 396 Pfam PF13173 AAA domain 47 179 5.5E-22 T 23-10-2018 STK_11430 cfde47db4a5f139edecc553a92645472 396 Gene3D G3DSA:3.40.50.300 16 149 2.8E-7 T 23-10-2018 STK_11430 cfde47db4a5f139edecc553a92645472 396 SMART SM00382 43 174 4.5E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_15350 a6b8535b3dcee65ffeb6f8c66c50f6bf 121 Pfam PF05942 Archaeal PaREP1/PaREP8 family 19 115 7.5E-19 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_10300 56ca768855c1bb14a934afddf9c1d48f 325 SUPERFAMILY SSF56300 18 322 1.74E-68 T 23-10-2018 STK_10300 56ca768855c1bb14a934afddf9c1d48f 325 Gene3D G3DSA:3.60.21.10 80 323 9.1E-21 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like STK_10300 56ca768855c1bb14a934afddf9c1d48f 325 Pfam PF00149 Calcineurin-like phosphoesterase 18 281 1.7E-6 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 STK_02840 70239692fa9015a48a7dd7158ed30af8 195 SUPERFAMILY SSF56281 4 169 9.23E-13 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_02840 70239692fa9015a48a7dd7158ed30af8 195 Gene3D G3DSA:3.60.15.10 1 190 7.0E-10 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_02084 15e3dc953dbdcaec787dffa498eaabd5 67 Pfam PF07754 Domain of unknown function (DUF1610) 18 41 3.7E-14 T 23-10-2018 IPR011668 Domain of unknown function DUF1610 STK_20500 36e8054650b39a39cf6c83d96c1ac1a5 128 Gene3D G3DSA:1.10.10.10 17 121 8.5E-34 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_20500 36e8054650b39a39cf6c83d96c1ac1a5 128 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 25 99 7.2E-16 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal STK_20500 36e8054650b39a39cf6c83d96c1ac1a5 128 SUPERFAMILY SSF46785 27 124 3.69E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_03970 a12aef0c72baf05792bd4745a97594e3 248 SUPERFAMILY SSF55979 128 248 1.51E-26 T 23-10-2018 STK_03970 a12aef0c72baf05792bd4745a97594e3 248 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 144 246 1.6E-7 T 23-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 STK_03970 a12aef0c72baf05792bd4745a97594e3 248 Gene3D G3DSA:3.70.10.10 1 243 2.4E-77 T 23-10-2018 STK_03970 a12aef0c72baf05792bd4745a97594e3 248 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 1 112 9.3E-7 T 23-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 STK_03970 a12aef0c72baf05792bd4745a97594e3 248 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 2 248 23.248 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 STK_03970 a12aef0c72baf05792bd4745a97594e3 248 SUPERFAMILY SSF55979 1 108 1.14E-22 T 23-10-2018 STK_08815 2969501aa76d5bf72e9e119f881c16e5 83 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 14 38 - T 23-10-2018 IPR001455 TusA-like domain STK_08815 2969501aa76d5bf72e9e119f881c16e5 83 SUPERFAMILY SSF64307 7 81 3.66E-19 T 23-10-2018 IPR036868 TusA-like domain superfamily STK_08815 2969501aa76d5bf72e9e119f881c16e5 83 Gene3D G3DSA:3.30.110.40 9 81 6.2E-21 T 23-10-2018 IPR036868 TusA-like domain superfamily STK_08815 2969501aa76d5bf72e9e119f881c16e5 83 Pfam PF01206 Sulfurtransferase TusA 13 81 1.6E-19 T 23-10-2018 IPR001455 TusA-like domain STK_24280 edc8f582af712c79c632e9435efeb3a1 458 SUPERFAMILY SSF103473 10 446 1.96E-57 T 23-10-2018 IPR036259 MFS transporter superfamily STK_24280 edc8f582af712c79c632e9435efeb3a1 458 ProSitePatterns PS00216 Sugar transport proteins signature 1. 311 327 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 STK_24280 edc8f582af712c79c632e9435efeb3a1 458 Pfam PF00083 Sugar (and other) transporter 28 446 1.9E-54 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 STK_24280 edc8f582af712c79c632e9435efeb3a1 458 ProSitePatterns PS00217 Sugar transport proteins signature 2. 123 148 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 STK_20510 c3e49d16dc3c1a00e52b9a9c59eddb0e 242 SUPERFAMILY SSF51556 1 242 1.97E-57 T 23-10-2018 IPR032466 Metal-dependent hydrolase STK_20510 c3e49d16dc3c1a00e52b9a9c59eddb0e 242 PIRSF PIRSF005902 1 242 3.7E-57 T 23-10-2018 IPR001130 TatD family GO:0016788 STK_20510 c3e49d16dc3c1a00e52b9a9c59eddb0e 242 Gene3D G3DSA:3.20.20.140 1 242 4.3E-65 T 23-10-2018 STK_20510 c3e49d16dc3c1a00e52b9a9c59eddb0e 242 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 23-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 STK_20510 c3e49d16dc3c1a00e52b9a9c59eddb0e 242 Pfam PF01026 TatD related DNase 3 241 4.1E-55 T 23-10-2018 IPR001130 TatD family GO:0016788 STK_03640 3d5be9193099ae01a30cd63361908eda 218 Gene3D G3DSA:3.30.200.20 12 84 2.3E-20 T 23-10-2018 STK_03640 3d5be9193099ae01a30cd63361908eda 218 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 120 132 - T 23-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 STK_03640 3d5be9193099ae01a30cd63361908eda 218 Pfam PF01163 RIO1 family 41 144 1.2E-8 T 23-10-2018 STK_03640 3d5be9193099ae01a30cd63361908eda 218 TIGRFAM TIGR03724 arch_bud32: Kae1-associated kinase Bud32 7 208 8.2E-75 T 23-10-2018 IPR022495 Serine/threonine-protein kinase Bud32 GO:0004674 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 STK_03640 3d5be9193099ae01a30cd63361908eda 218 SUPERFAMILY SSF56112 2 166 3.24E-25 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily STK_03640 3d5be9193099ae01a30cd63361908eda 218 Gene3D G3DSA:1.10.510.10 92 209 1.1E-25 T 23-10-2018 STK_13448 a17b5dc542ca1d8c5846a7a906042589 98 Pfam PF06005 Cell division protein ZapB 6 91 8.3E-25 T 23-10-2018 IPR009252 Cell division protein ZapB GO:0005737|GO:0043093|GO:0090529 STK_24780 2b2181bf5b73762d1425ec328ee351a3 311 SUPERFAMILY SSF53613 1 306 2.03E-70 T 23-10-2018 IPR029056 Ribokinase-like STK_24780 2b2181bf5b73762d1425ec328ee351a3 311 Gene3D G3DSA:3.40.1190.20 1 311 8.4E-122 T 23-10-2018 IPR029056 Ribokinase-like STK_24780 2b2181bf5b73762d1425ec328ee351a3 311 Pfam PF00294 pfkB family carbohydrate kinase 1 298 2.4E-44 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB STK_22540 1aac139235ced2348ad728a54da47dff 368 Pfam PF07690 Major Facilitator Superfamily 4 326 1.1E-15 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_22540 1aac139235ced2348ad728a54da47dff 368 SUPERFAMILY SSF103473 3 362 1.29E-19 T 23-10-2018 IPR036259 MFS transporter superfamily STK_22540 1aac139235ced2348ad728a54da47dff 368 Gene3D G3DSA:1.20.1250.20 3 358 1.5E-16 T 23-10-2018 STK_02140 893d1a7623d97429e0b83f413d9047fe 336 SMART SM01004 4 330 8.2E-220 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 STK_02140 893d1a7623d97429e0b83f413d9047fe 336 SUPERFAMILY SSF51569 2 332 6.84E-134 T 23-10-2018 STK_02140 893d1a7623d97429e0b83f413d9047fe 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 196 215 5.8E-57 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 STK_02140 893d1a7623d97429e0b83f413d9047fe 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 158 177 5.8E-57 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 STK_02140 893d1a7623d97429e0b83f413d9047fe 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 304 323 5.8E-57 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 STK_02140 893d1a7623d97429e0b83f413d9047fe 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 124 138 5.8E-57 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 STK_02140 893d1a7623d97429e0b83f413d9047fe 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 248 264 5.8E-57 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 STK_02140 893d1a7623d97429e0b83f413d9047fe 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 274 289 5.8E-57 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 STK_02140 893d1a7623d97429e0b83f413d9047fe 336 PIRSF PIRSF001415 1 333 1.6E-148 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 STK_02140 893d1a7623d97429e0b83f413d9047fe 336 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 248 260 - T 23-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 STK_02140 893d1a7623d97429e0b83f413d9047fe 336 Gene3D G3DSA:3.20.20.70 1 336 5.4E-146 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_02140 893d1a7623d97429e0b83f413d9047fe 336 Pfam PF00490 Delta-aminolevulinic acid dehydratase 8 329 1.2E-139 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 STK_22430 0ace97d8d2844afa0d4f302a56934707 146 Pfam PF00293 NUDIX domain 6 116 7.2E-22 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 STK_22430 0ace97d8d2844afa0d4f302a56934707 146 SUPERFAMILY SSF55811 3 130 2.71E-36 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 STK_22430 0ace97d8d2844afa0d4f302a56934707 146 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 23-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 STK_22430 0ace97d8d2844afa0d4f302a56934707 146 Gene3D G3DSA:3.90.79.10 1 135 1.3E-37 T 23-10-2018 STK_22430 0ace97d8d2844afa0d4f302a56934707 146 PRINTS PR00502 NUDIX hydrolase family signature 47 62 1.1E-7 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 STK_22430 0ace97d8d2844afa0d4f302a56934707 146 PRINTS PR00502 NUDIX hydrolase family signature 33 47 1.1E-7 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 STK_22370 11e1dbd641fcc3713360d9afbc9f5273 281 Pfam PF01925 Sulfite exporter TauE/SafE 13 269 4.9E-52 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 STK_08250 ffd48e88f2c1cc293c51caf48a1823b1 202 Pfam PF08241 Methyltransferase domain 115 160 3.6E-5 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 STK_08250 ffd48e88f2c1cc293c51caf48a1823b1 202 SUPERFAMILY SSF53335 123 168 6.36E-7 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_08250 ffd48e88f2c1cc293c51caf48a1823b1 202 Gene3D G3DSA:3.40.50.150 98 190 2.1E-6 T 23-10-2018 STK_22380 72a0f1a25a338a362ce2b532cbf6c89f 220 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 14 189 2.4E-74 T 23-10-2018 IPR005273 Uracil-DNA glycosylase family 4 STK_22380 72a0f1a25a338a362ce2b532cbf6c89f 220 Gene3D G3DSA:3.40.470.10 1 194 6.0E-79 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 STK_22380 72a0f1a25a338a362ce2b532cbf6c89f 220 Pfam PF03167 Uracil DNA glycosylase superfamily 28 176 1.1E-45 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 STK_22380 72a0f1a25a338a362ce2b532cbf6c89f 220 SMART SM00986 28 183 2.2E-38 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 STK_22380 72a0f1a25a338a362ce2b532cbf6c89f 220 SUPERFAMILY SSF52141 2 187 7.52E-61 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 STK_22380 72a0f1a25a338a362ce2b532cbf6c89f 220 SMART SM00987 28 183 2.2E-38 T 23-10-2018 STK_03370 f57b002e19bf6c94a0349b257f76667f 109 SUPERFAMILY SSF81301 22 105 2.52E-11 T 23-10-2018 STK_03370 f57b002e19bf6c94a0349b257f76667f 109 Gene3D G3DSA:3.30.460.10 5 106 2.9E-9 T 23-10-2018 STK_08730 71e2077774f0ce3369fe62a9de8ec4c6 502 SMART SM00729 183 412 1.4E-25 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 STK_08730 71e2077774f0ce3369fe62a9de8ec4c6 502 SUPERFAMILY SSF102114 176 421 6.18E-16 T 23-10-2018 STK_08730 71e2077774f0ce3369fe62a9de8ec4c6 502 Pfam PF04055 Radical SAM superfamily 188 371 7.6E-16 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_08730 71e2077774f0ce3369fe62a9de8ec4c6 502 Gene3D G3DSA:3.80.30.20 183 394 6.1E-22 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe STK_17400 581f8b7fa9b336e8eb1f96e0a379a39d 109 Pfam PF05942 Archaeal PaREP1/PaREP8 family 35 108 1.8E-22 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_17400 581f8b7fa9b336e8eb1f96e0a379a39d 109 Gene3D G3DSA:1.20.120.330 35 109 1.3E-23 T 23-10-2018 STK_04430 6b61b773a1953a2cd50feab37db1f0d2 243 Pfam PF01138 3' exoribonuclease family, domain 1 24 153 9.6E-36 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 STK_04430 6b61b773a1953a2cd50feab37db1f0d2 243 Hamap MF_00591 Exosome complex component Rrp41 [rrp41]. 5 241 59.0 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 STK_04430 6b61b773a1953a2cd50feab37db1f0d2 243 Pfam PF03725 3' exoribonuclease family, domain 2 156 221 1.1E-13 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 STK_04430 6b61b773a1953a2cd50feab37db1f0d2 243 TIGRFAM TIGR02065 ECX1: exosome complex exonuclease 1 9 237 2.7E-123 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 STK_04430 6b61b773a1953a2cd50feab37db1f0d2 243 SUPERFAMILY SSF54211 8 180 2.99E-48 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold STK_04430 6b61b773a1953a2cd50feab37db1f0d2 243 SUPERFAMILY SSF55666 153 240 8.25E-25 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 STK_04430 6b61b773a1953a2cd50feab37db1f0d2 243 Gene3D G3DSA:3.30.230.70 3 242 1.0E-76 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 STK_20480 32fa98620f5263a777b9610d0d70a19d 222 TIGRFAM TIGR03679 arCOG00187: arCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein 4 220 1.7E-83 T 23-10-2018 IPR022427 Uncharacterised protein MJ0570, ATP-binding STK_20480 32fa98620f5263a777b9610d0d70a19d 222 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 1 218 1.1E-60 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 STK_20480 32fa98620f5263a777b9610d0d70a19d 222 Gene3D G3DSA:3.90.1490.10 126 222 1.9E-23 T 23-10-2018 STK_20480 32fa98620f5263a777b9610d0d70a19d 222 Pfam PF01902 Diphthamide synthase 1 219 1.0E-60 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 STK_20480 32fa98620f5263a777b9610d0d70a19d 222 PIRSF PIRSF039123 1 222 6.6E-70 T 23-10-2018 IPR030662 Diphthine--ammonia ligase/Uncharacterised protein MJ0570 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 STK_20480 32fa98620f5263a777b9610d0d70a19d 222 SUPERFAMILY SSF52402 1 220 4.93E-67 T 23-10-2018 STK_20480 32fa98620f5263a777b9610d0d70a19d 222 Gene3D G3DSA:3.40.50.620 1 125 5.3E-37 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold STK_04530 62a84b2a7cc18b28e9ffd013c275229e 193 SMART SM01397 2 192 5.6E-104 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04530 62a84b2a7cc18b28e9ffd013c275229e 193 Pfam PF01015 Ribosomal S3Ae family 4 192 2.6E-67 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04530 62a84b2a7cc18b28e9ffd013c275229e 193 Hamap MF_00359 30S ribosomal protein S3Ae [rps3ae]. 2 192 35.867 T 23-10-2018 IPR030838 30S ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 STK_23310 3fa3b4d9691566637b0d5659914124b7 203 Pfam PF12705 PD-(D/E)XK nuclease superfamily 78 198 1.5E-10 T 23-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type STK_23310 3fa3b4d9691566637b0d5659914124b7 203 SUPERFAMILY SSF52980 90 177 5.29E-7 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 STK_23310 3fa3b4d9691566637b0d5659914124b7 203 Gene3D G3DSA:3.90.320.10 1 202 4.0E-73 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal STK_23310 3fa3b4d9691566637b0d5659914124b7 203 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 22 198 2.9E-46 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 STK_16210 796809638267b635bddf79d0352abd41 194 Pfam PF08241 Methyltransferase domain 34 120 5.4E-20 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 STK_16210 796809638267b635bddf79d0352abd41 194 SUPERFAMILY SSF53335 17 178 2.73E-30 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_16210 796809638267b635bddf79d0352abd41 194 Gene3D G3DSA:3.40.50.150 12 183 2.0E-31 T 23-10-2018 STK_08680 c8e34ad25898dfae28dfed36f1010e87 683 Pfam PF12215 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term 12 292 1.4E-20 T 23-10-2018 IPR024462 Glycosyl-hydrolase family 116, N-terminal KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 STK_08680 c8e34ad25898dfae28dfed36f1010e87 683 Gene3D G3DSA:1.50.10.10 364 677 8.5E-26 T 23-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 STK_08680 c8e34ad25898dfae28dfed36f1010e87 683 SUPERFAMILY SSF48208 288 667 5.95E-34 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 STK_08680 c8e34ad25898dfae28dfed36f1010e87 683 Pfam PF04685 Glycosyl-hydrolase family 116, catalytic region 334 669 9.8E-60 T 23-10-2018 IPR006775 Glycosyl-hydrolase family 116, catalytic region GO:0004553 KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 STK_15110 68ad09544c8247fae813a093e7579cda 162 Gene3D G3DSA:3.40.1520.10 1 162 1.2E-82 T 23-10-2018 IPR036902 Ta1353-like superfamily STK_15110 68ad09544c8247fae813a093e7579cda 162 SUPERFAMILY SSF103165 3 161 8.76E-75 T 23-10-2018 IPR036902 Ta1353-like superfamily STK_15110 68ad09544c8247fae813a093e7579cda 162 Pfam PF04008 Adenosine specific kinase 8 161 3.6E-78 T 23-10-2018 IPR007153 Adenosine specific kinase STK_21290 e35feb81252608a60e493642ba8c8400 219 SUPERFAMILY SSF75217 2 216 1.92E-56 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases STK_21290 e35feb81252608a60e493642ba8c8400 219 Pfam PF03587 EMG1/NEP1 methyltransferase 5 212 2.1E-44 T 23-10-2018 IPR005304 Ribosomal biogenesis, methyltransferase, EMG1/NEP1 GO:0008168 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 STK_21290 e35feb81252608a60e493642ba8c8400 219 Hamap MF_00554 Ribosomal RNA small subunit methyltransferase Nep1 [nep1]. 3 215 33.202 T 23-10-2018 IPR023503 Ribosome biogenesis methyltransferase NEP1, archaea GO:0008168 STK_21290 e35feb81252608a60e493642ba8c8400 219 Gene3D G3DSA:3.40.1280.10 1 216 7.4E-68 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal STK_25650 fae1ea10fd54ce63f6db4121ef7b37b5 188 Gene3D G3DSA:3.30.950.10 69 187 8.4E-26 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 STK_25650 fae1ea10fd54ce63f6db4121ef7b37b5 188 SUPERFAMILY SSF53790 8 184 4.71E-39 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 STK_25650 fae1ea10fd54ce63f6db4121ef7b37b5 188 Gene3D G3DSA:3.40.1010.10 9 68 6.0E-13 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 STK_25650 fae1ea10fd54ce63f6db4121ef7b37b5 188 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 33 66 - T 23-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 STK_25650 fae1ea10fd54ce63f6db4121ef7b37b5 188 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 17 161 1.0E-29 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 STK_14580 8c3cdba9c8a980e63926f4ea825eb2d0 357 SUPERFAMILY SSF53383 23 350 7.26E-72 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase STK_14580 8c3cdba9c8a980e63926f4ea825eb2d0 357 Gene3D G3DSA:3.40.640.10 52 268 9.0E-85 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 STK_14580 8c3cdba9c8a980e63926f4ea825eb2d0 357 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 218 227 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 STK_14580 8c3cdba9c8a980e63926f4ea825eb2d0 357 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 24 350 1.5E-90 T 23-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 STK_14580 8c3cdba9c8a980e63926f4ea825eb2d0 357 Pfam PF00155 Aminotransferase class I and II 30 346 5.0E-46 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 STK_14580 8c3cdba9c8a980e63926f4ea825eb2d0 357 Gene3D G3DSA:3.90.1150.10 26 346 9.0E-85 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 STK_09750 2d9462a9586bd04b005983d6067a91ed 237 Pfam PF01048 Phosphorylase superfamily 17 219 1.3E-36 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 STK_09750 2d9462a9586bd04b005983d6067a91ed 237 Gene3D G3DSA:3.40.50.1580 1 235 4.6E-71 T 23-10-2018 STK_09750 2d9462a9586bd04b005983d6067a91ed 237 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 23-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 STK_09750 2d9462a9586bd04b005983d6067a91ed 237 SUPERFAMILY SSF53167 4 234 1.02E-72 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 STK_22130 684c51fb6bd4624d4dfdcd2587e59b6c 385 Gene3D G3DSA:3.40.30.10 2 107 2.1E-5 T 23-10-2018 STK_22130 684c51fb6bd4624d4dfdcd2587e59b6c 385 SUPERFAMILY SSF48208 181 321 4.0E-12 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 STK_22130 684c51fb6bd4624d4dfdcd2587e59b6c 385 SUPERFAMILY SSF52833 3 98 1.56E-8 T 23-10-2018 IPR036249 Thioredoxin-like superfamily STK_22130 684c51fb6bd4624d4dfdcd2587e59b6c 385 Gene3D G3DSA:1.50.10.20 182 325 8.5E-6 T 23-10-2018 STK_15940 76503ebdc27d15109e42c8b352792cdc 125 Pfam PF04343 Protein of unknown function, DUF488 13 118 3.5E-27 T 23-10-2018 IPR007438 Protein of unknown function DUF488 STK_10780 062b2bea321b3c48c27bf46183e9bce5 316 Pfam PF12773 Double zinc ribbon 263 307 1.0E-12 T 23-10-2018 IPR025874 Double zinc ribbon STK_00340 7bda90ef45b38d4fc2388310af8f4663 255 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 131 246 2.6E-16 T 23-10-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal STK_00340 7bda90ef45b38d4fc2388310af8f4663 255 Gene3D G3DSA:3.30.70.1900 118 251 1.5E-36 T 23-10-2018 STK_00340 7bda90ef45b38d4fc2388310af8f4663 255 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 40 247 1.5E-41 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 STK_00340 7bda90ef45b38d4fc2388310af8f4663 255 Gene3D G3DSA:3.30.70.2990 1 117 2.6E-8 T 23-10-2018 STK_02920 688b27e797e502bf8d2bc42e1ae6ec1b 466 Pfam PF03486 HI0933-like protein 4 44 1.1E-6 T 23-10-2018 STK_02920 688b27e797e502bf8d2bc42e1ae6ec1b 466 Gene3D G3DSA:3.50.50.60 120 230 9.1E-6 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_02920 688b27e797e502bf8d2bc42e1ae6ec1b 466 Gene3D G3DSA:3.50.50.60 3 119 1.6E-18 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_02920 688b27e797e502bf8d2bc42e1ae6ec1b 466 Pfam PF01134 Glucose inhibited division protein A 372 462 1.6E-4 T 23-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 STK_02920 688b27e797e502bf8d2bc42e1ae6ec1b 466 SUPERFAMILY SSF51905 3 460 3.38E-29 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_02920 688b27e797e502bf8d2bc42e1ae6ec1b 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.5E-7 T 23-10-2018 STK_02920 688b27e797e502bf8d2bc42e1ae6ec1b 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 417 439 1.5E-7 T 23-10-2018 STK_02920 688b27e797e502bf8d2bc42e1ae6ec1b 466 PIRSF PIRSF038984 118 465 3.1E-26 T 23-10-2018 IPR028348 FAD dependent protein STK_02920 688b27e797e502bf8d2bc42e1ae6ec1b 466 PIRSF PIRSF038984 3 120 8.6E-9 T 23-10-2018 IPR028348 FAD dependent protein STK_05400 ddffce343be597a7bf77c15d101d3380 136 Pfam PF05168 HEPN domain 9 128 1.6E-5 T 23-10-2018 IPR007842 HEPN domain STK_09080 e6a851d27105801f47aa559ffb3651b9 195 Pfam PF07676 WD40-like Beta Propeller Repeat 53 76 3.3E-4 T 23-10-2018 IPR011659 WD40-like Beta Propeller STK_09080 e6a851d27105801f47aa559ffb3651b9 195 Gene3D G3DSA:2.120.10.60 10 195 1.1E-39 T 23-10-2018 STK_09080 e6a851d27105801f47aa559ffb3651b9 195 SUPERFAMILY SSF69304 21 187 1.14E-24 T 23-10-2018 STK_22720 2f240e017bc54d0b34d832d7ab858b86 352 SUPERFAMILY SSF56796 5 345 1.57E-88 T 23-10-2018 STK_22720 2f240e017bc54d0b34d832d7ab858b86 352 Gene3D G3DSA:1.20.1090.10 162 350 5.9E-50 T 23-10-2018 STK_22720 2f240e017bc54d0b34d832d7ab858b86 352 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 352 60.239 T 23-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 STK_22720 2f240e017bc54d0b34d832d7ab858b86 352 Pfam PF01761 3-dehydroquinate synthase 57 317 1.7E-94 T 23-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 STK_22720 2f240e017bc54d0b34d832d7ab858b86 352 PIRSF PIRSF001455 2 351 8.8E-113 T 23-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 STK_22720 2f240e017bc54d0b34d832d7ab858b86 352 Gene3D G3DSA:3.40.50.1970 2 161 5.2E-48 T 23-10-2018 STK_22720 2f240e017bc54d0b34d832d7ab858b86 352 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 5 338 1.8E-107 T 23-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 STK_06710 2ce6a57d0478a842e519b33c07016501 265 SUPERFAMILY SSF46689 70 152 2.82E-10 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 STK_06710 2ce6a57d0478a842e519b33c07016501 265 Pfam PF13384 Homeodomain-like domain 73 111 8.3E-8 T 23-10-2018 STK_06710 2ce6a57d0478a842e519b33c07016501 265 Gene3D G3DSA:1.10.10.10 70 117 3.2E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_04900 e2c92aec0bf95aed9faa5f97dd3a59a7 331 Gene3D G3DSA:3.30.9.10 64 311 2.6E-30 T 23-10-2018 STK_04900 e2c92aec0bf95aed9faa5f97dd3a59a7 331 SUPERFAMILY SSF51905 1 270 5.3E-20 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_04900 e2c92aec0bf95aed9faa5f97dd3a59a7 331 Gene3D G3DSA:3.50.50.60 2 297 2.6E-30 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_04900 e2c92aec0bf95aed9faa5f97dd3a59a7 331 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 37 3.2E-6 T 23-10-2018 STK_01810 5ee4f21eb8c2298f90f35969d9c6879d 577 Gene3D G3DSA:3.40.50.300 147 288 5.2E-15 T 23-10-2018 STK_01810 5ee4f21eb8c2298f90f35969d9c6879d 577 Gene3D G3DSA:3.40.50.300 386 572 1.2E-21 T 23-10-2018 STK_01810 5ee4f21eb8c2298f90f35969d9c6879d 577 SUPERFAMILY SSF52540 130 533 2.03E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_01810 5ee4f21eb8c2298f90f35969d9c6879d 577 Pfam PF01935 Domain of unknown function DUF87 158 407 5.1E-20 T 23-10-2018 IPR002789 Helicase HerA, central domain STK_19680 47da47559265a206ea86626bccfef0ee 260 Gene3D G3DSA:3.90.550.10 1 218 2.8E-13 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_19680 47da47559265a206ea86626bccfef0ee 260 SUPERFAMILY SSF53448 2 195 4.73E-17 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_19680 47da47559265a206ea86626bccfef0ee 260 Pfam PF00535 Glycosyl transferase family 2 12 81 4.7E-7 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 STK_06600 41aac2748684e6f443b93347edafc491 164 Pfam PF13240 zinc-ribbon domain 141 163 2.2E-8 T 23-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 STK_23130 493f7243b26f6117b29f22247f7b998e 325 SUPERFAMILY SSF51971 2 301 1.29E-16 T 23-10-2018 STK_23130 493f7243b26f6117b29f22247f7b998e 325 Pfam PF01266 FAD dependent oxidoreductase 138 294 1.6E-7 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 STK_23130 493f7243b26f6117b29f22247f7b998e 325 Gene3D G3DSA:3.30.9.10 166 262 4.4E-14 T 23-10-2018 STK_23130 493f7243b26f6117b29f22247f7b998e 325 Gene3D G3DSA:3.50.50.60 138 302 4.4E-14 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_18320 06b54d49a156434ac83fbfac8b75433d 442 Pfam PF00324 Amino acid permease 24 417 1.1E-20 T 23-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 STK_18320 06b54d49a156434ac83fbfac8b75433d 442 PIRSF PIRSF006060 1 439 8.5E-51 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_18320 06b54d49a156434ac83fbfac8b75433d 442 Gene3D G3DSA:1.20.1740.10 12 442 8.7E-31 T 23-10-2018 STK_20000 6475cdd538397cce0f090376d0bd4e64 105 Pfam PF04693 Archaeal putative transposase ISC1217 4 38 1.2E-11 T 23-10-2018 IPR006783 Transposase, ISC1217 STK_08110 063616bc7e17abcf6a74c902d0af1e1e 125 Pfam PF01042 Endoribonuclease L-PSP 7 122 1.2E-43 T 23-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 STK_08110 063616bc7e17abcf6a74c902d0af1e1e 125 Gene3D G3DSA:3.30.1330.40 1 125 1.4E-58 T 23-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 STK_08110 063616bc7e17abcf6a74c902d0af1e1e 125 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 2 122 2.0E-50 T 23-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 STK_08110 063616bc7e17abcf6a74c902d0af1e1e 125 SUPERFAMILY SSF55298 3 124 1.88E-46 T 23-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 STK_08110 063616bc7e17abcf6a74c902d0af1e1e 125 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 100 118 - T 23-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 STK_04480 e7cc5b025abc660ba310b75643a9ff36 181 Gene3D G3DSA:3.20.20.140 2 178 2.7E-9 T 23-10-2018 STK_04480 e7cc5b025abc660ba310b75643a9ff36 181 SUPERFAMILY SSF89550 4 175 3.45E-16 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 STK_17900 65beb18231306d9e19e67d2b2655b36f 133 Pfam PF03061 Thioesterase superfamily 47 122 1.6E-11 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 STK_17900 65beb18231306d9e19e67d2b2655b36f 133 SUPERFAMILY SSF54637 5 132 1.98E-22 T 23-10-2018 IPR029069 HotDog domain superfamily STK_17900 65beb18231306d9e19e67d2b2655b36f 133 Gene3D G3DSA:3.10.129.10 2 130 5.3E-26 T 23-10-2018 STK_17900 65beb18231306d9e19e67d2b2655b36f 133 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 17 126 7.9E-11 T 23-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 STK_19010 a957f10a8745564f73c90ea1e1e76392 403 Pfam PF01566 Natural resistance-associated macrophage protein 38 378 1.3E-43 T 23-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 STK_05490 bcd3e436aa45e12de97040db4f356cc0 517 Gene3D G3DSA:3.50.50.60 4 124 4.1E-15 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_05490 bcd3e436aa45e12de97040db4f356cc0 517 PRINTS PR00419 Adrenodoxin reductase family signature 29 42 1.2E-5 T 23-10-2018 STK_05490 bcd3e436aa45e12de97040db4f356cc0 517 PRINTS PR00419 Adrenodoxin reductase family signature 6 28 1.2E-5 T 23-10-2018 STK_05490 bcd3e436aa45e12de97040db4f356cc0 517 Gene3D G3DSA:3.50.50.60 178 338 1.2E-22 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_05490 bcd3e436aa45e12de97040db4f356cc0 517 Pfam PF13450 NAD(P)-binding Rossmann-like domain 9 63 3.3E-11 T 23-10-2018 STK_05490 bcd3e436aa45e12de97040db4f356cc0 517 SUPERFAMILY SSF51905 5 499 1.3E-46 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_00370 95f781c50c5dc8dd99b5751d00dd7053 157 SUPERFAMILY SSF81301 3 120 2.36E-21 T 23-10-2018 STK_00370 95f781c50c5dc8dd99b5751d00dd7053 157 Gene3D G3DSA:3.30.460.10 1 122 1.0E-22 T 23-10-2018 STK_00370 95f781c50c5dc8dd99b5751d00dd7053 157 Pfam PF01909 Nucleotidyltransferase domain 17 104 1.3E-11 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_12645 41cec216ef512d36f4cb0c8cde664304 55 Pfam PF04758 Ribosomal protein S30 4 47 8.1E-14 T 23-10-2018 IPR006846 Ribosomal protein S30 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_06560 547be670902b3bc93d04c961f80dfac9 223 Gene3D G3DSA:3.40.50.1860 1 93 1.6E-46 T 23-10-2018 STK_06560 547be670902b3bc93d04c961f80dfac9 223 Gene3D G3DSA:3.40.50.11330 94 223 1.1E-44 T 23-10-2018 STK_10320 f910abe57a5e5e43f57d106ed7eae64f 542 PIRSF PIRSF006060 20 538 1.7E-19 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_04470 ba93e08fbcbe0b0c747e1661b547ea8a 123 Gene3D G3DSA:3.30.70.3250 10 122 1.1E-22 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 STK_04470 ba93e08fbcbe0b0c747e1661b547ea8a 123 SUPERFAMILY SSF160350 25 119 3.14E-21 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 STK_04470 ba93e08fbcbe0b0c747e1661b547ea8a 123 Pfam PF01900 Rpp14/Pop5 family 26 118 6.7E-11 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 STK_04470 ba93e08fbcbe0b0c747e1661b547ea8a 123 Hamap MF_00755 Ribonuclease P protein component 2 [rnp2]. 9 123 21.755 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 STK_14090 2c61166878597c216374cd49d60d6a74 103 SUPERFAMILY SSF46689 6 76 1.97E-5 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 STK_14090 2c61166878597c216374cd49d60d6a74 103 Pfam PF01381 Helix-turn-helix 21 57 3.5E-9 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 STK_14090 2c61166878597c216374cd49d60d6a74 103 Gene3D G3DSA:1.10.260.40 4 99 1.2E-5 T 23-10-2018 STK_14090 2c61166878597c216374cd49d60d6a74 103 SMART SM00530 15 68 0.0062 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 STK_11120 12b258cd9705725f44fdcb0ab42a67c5 504 ProSitePatterns PS00455 Putative AMP-binding domain signature. 171 182 - T 23-10-2018 IPR020845 AMP-binding, conserved site STK_11120 12b258cd9705725f44fdcb0ab42a67c5 504 SUPERFAMILY SSF56801 26 501 6.41E-133 T 23-10-2018 STK_11120 12b258cd9705725f44fdcb0ab42a67c5 504 Gene3D G3DSA:3.30.300.310 403 503 2.6E-30 T 23-10-2018 STK_11120 12b258cd9705725f44fdcb0ab42a67c5 504 Pfam PF00501 AMP-binding enzyme 26 405 7.0E-87 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 STK_11120 12b258cd9705725f44fdcb0ab42a67c5 504 Gene3D G3DSA:3.40.50.12780 13 402 8.1E-92 T 23-10-2018 STK_11120 12b258cd9705725f44fdcb0ab42a67c5 504 Pfam PF13193 AMP-binding enzyme C-terminal domain 415 493 2.3E-23 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain STK_14385 e2a09c66c522a3de22942d7877512f79 59 Pfam PF08112 ATP synthase epsilon subunit 1 56 1.1E-33 T 23-10-2018 IPR012508 ATPase, A1 complex, epsilon subunit, archaeal GO:0015986|GO:0033178|GO:0042626 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 STK_14385 e2a09c66c522a3de22942d7877512f79 59 ProDom PD052431 CHAIN ION EPSILON HYDROLASE SUL-ATPASE HYDROGEN ATPASE MEMBRANE-ASSOCIATED SYNTHASE G 10 57 2.0E-18 T 23-10-2018 IPR012508 ATPase, A1 complex, epsilon subunit, archaeal GO:0015986|GO:0033178|GO:0042626 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 STK_04440 29d88f61795fa8edc8162daede4dd91e 247 SUPERFAMILY SSF54791 150 231 1.83E-16 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 STK_04440 29d88f61795fa8edc8162daede4dd91e 247 Gene3D G3DSA:2.40.50.140 63 153 8.8E-22 T 23-10-2018 STK_04440 29d88f61795fa8edc8162daede4dd91e 247 Gene3D G3DSA:2.40.50.100 1 61 1.1E-24 T 23-10-2018 STK_04440 29d88f61795fa8edc8162daede4dd91e 247 SMART SM00322 148 212 2.4E-5 T 23-10-2018 IPR004087 K Homology domain GO:0003676 STK_04440 29d88f61795fa8edc8162daede4dd91e 247 Hamap MF_00623 Exosome complex component Rrp4 [rrp4]. 9 234 36.922 T 23-10-2018 IPR023474 Exosome complex component Rrp4 GO:0000178|GO:0008143 STK_04440 29d88f61795fa8edc8162daede4dd91e 247 SMART SM00316 68 141 1.0E-7 T 23-10-2018 IPR022967 RNA-binding domain, S1 STK_04440 29d88f61795fa8edc8162daede4dd91e 247 Gene3D G3DSA:3.30.1370.10 154 247 8.1E-32 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 STK_04440 29d88f61795fa8edc8162daede4dd91e 247 SUPERFAMILY SSF50249 63 154 1.9E-20 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold STK_04440 29d88f61795fa8edc8162daede4dd91e 247 SUPERFAMILY SSF110324 5 62 6.28E-16 T 23-10-2018 STK_04440 29d88f61795fa8edc8162daede4dd91e 247 Pfam PF00013 KH domain 153 186 1.3E-4 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 STK_21800 00b4dc6144ec086cb05f2c7a9e5bbfa1 172 Pfam PF01923 Cobalamin adenosyltransferase 3 156 5.8E-47 T 23-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 STK_21800 00b4dc6144ec086cb05f2c7a9e5bbfa1 172 Gene3D G3DSA:1.20.1200.10 22 172 1.9E-58 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 STK_21800 00b4dc6144ec086cb05f2c7a9e5bbfa1 172 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 3 169 1.2E-65 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 STK_21800 00b4dc6144ec086cb05f2c7a9e5bbfa1 172 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 8 168 6.0E-78 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 STK_21800 00b4dc6144ec086cb05f2c7a9e5bbfa1 172 SUPERFAMILY SSF89028 2 169 8.24E-52 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 STK_24300 e3a5fd2c9b2f2d75047349966d8527f9 331 Pfam PF02371 Transposase IS116/IS110/IS902 family 210 295 1.7E-24 T 23-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 STK_03485 5965ba34f880477a9ec858ec8d4f6a42 88 Pfam PF01998 Protein of unknown function DUF131 14 75 1.1E-11 T 23-10-2018 IPR002849 Protein of unknown function DUF131 STK_13800 1285d2f860e694407490f270bf897df8 300 Gene3D G3DSA:3.40.50.1100 50 145 3.1E-70 T 23-10-2018 STK_13800 1285d2f860e694407490f270bf897df8 300 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 36 55 - T 23-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 STK_13800 1285d2f860e694407490f270bf897df8 300 Gene3D G3DSA:3.40.50.1100 22 293 3.1E-70 T 23-10-2018 STK_13800 1285d2f860e694407490f270bf897df8 300 SUPERFAMILY SSF53686 14 299 1.57E-68 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme STK_13800 1285d2f860e694407490f270bf897df8 300 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 284 1.2E-51 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme STK_08480 284592310a23ec3736a118eef2f4c98e 174 SUPERFAMILY SSF88723 6 119 5.89E-6 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_08100 09a86194252cf30b41796a449f8d0ae3 661 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 369 394 - T 23-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 STK_08100 09a86194252cf30b41796a449f8d0ae3 661 Gene3D G3DSA:1.10.510.10 358 647 7.9E-36 T 23-10-2018 STK_08100 09a86194252cf30b41796a449f8d0ae3 661 Pfam PF00069 Protein kinase domain 363 628 2.8E-27 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 STK_08100 09a86194252cf30b41796a449f8d0ae3 661 Gene3D G3DSA:1.25.40.10 105 357 3.9E-17 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 STK_08100 09a86194252cf30b41796a449f8d0ae3 661 Pfam PF12895 Anaphase-promoting complex, cyclosome, subunit 3 247 315 1.3E-8 T 23-10-2018 STK_08100 09a86194252cf30b41796a449f8d0ae3 661 SMART SM00220 363 644 2.2E-16 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 STK_08100 09a86194252cf30b41796a449f8d0ae3 661 SUPERFAMILY SSF56112 362 628 1.27E-41 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily STK_08100 09a86194252cf30b41796a449f8d0ae3 661 SUPERFAMILY SSF48452 226 327 2.7E-11 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 STK_08100 09a86194252cf30b41796a449f8d0ae3 661 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 491 503 - T 23-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 STK_20380 a549b14446fd8bbfc72127648349e0f0 111 Pfam PF10007 Uncharacterized protein conserved in archaea (DUF2250) 5 102 4.6E-6 T 23-10-2018 IPR019254 Protein of unknown function DUF2250 STK_20380 a549b14446fd8bbfc72127648349e0f0 111 Gene3D G3DSA:1.10.10.10 1 111 2.2E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_17170 d2a824162ecab87e7c1368c1afdc404f 289 Pfam PF01548 Transposase 12 158 1.2E-17 T 23-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 STK_17170 d2a824162ecab87e7c1368c1afdc404f 289 Pfam PF02371 Transposase IS116/IS110/IS902 family 240 278 1.8E-10 T 23-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 STK_05590 ab7dc42f2e18ea46cf4f87b42cc7eb15 144 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 5 141 2.0E-49 T 23-10-2018 IPR010419 Carbon monoxide dehydrogenase subunit G STK_05590 ab7dc42f2e18ea46cf4f87b42cc7eb15 144 SUPERFAMILY SSF55961 1 141 1.65E-30 T 23-10-2018 STK_05590 ab7dc42f2e18ea46cf4f87b42cc7eb15 144 Gene3D G3DSA:3.30.530.20 1 144 2.8E-30 T 23-10-2018 IPR023393 START-like domain superfamily STK_06410 beea0e6253193cf5cef1d3bf54fadb6e 156 Pfam PF05942 Archaeal PaREP1/PaREP8 family 35 147 2.7E-36 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_06410 beea0e6253193cf5cef1d3bf54fadb6e 156 Gene3D G3DSA:1.20.120.330 35 155 2.6E-37 T 23-10-2018 STK_00710 1e5f55fa4430c82ed6d5b2a16feec635 303 SUPERFAMILY SSF53474 36 300 3.21E-73 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold STK_00710 1e5f55fa4430c82ed6d5b2a16feec635 303 Gene3D G3DSA:3.40.50.1820 1 302 1.6E-96 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold STK_00710 1e5f55fa4430c82ed6d5b2a16feec635 303 Pfam PF07859 alpha/beta hydrolase fold 73 276 1.1E-69 T 23-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 STK_07420 25b909d7136e3d5c303d51ccc54b385d 174 PIRSF PIRSF024492 1 174 9.7E-65 T 23-10-2018 IPR014519 Uncharacterised conserved protein UCP024492 STK_07420 25b909d7136e3d5c303d51ccc54b385d 174 Pfam PF04343 Protein of unknown function, DUF488 12 138 4.1E-31 T 23-10-2018 IPR007438 Protein of unknown function DUF488 STK_12250 21ba645f2a97e4ea1b8180b0cb00ec03 399 Gene3D G3DSA:3.90.1150.10 30 389 8.0E-120 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 STK_12250 21ba645f2a97e4ea1b8180b0cb00ec03 399 Gene3D G3DSA:3.40.640.10 66 287 8.0E-120 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 STK_12250 21ba645f2a97e4ea1b8180b0cb00ec03 399 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 237 250 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 STK_12250 21ba645f2a97e4ea1b8180b0cb00ec03 399 SUPERFAMILY SSF53383 27 394 1.03E-106 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase STK_12250 21ba645f2a97e4ea1b8180b0cb00ec03 399 Pfam PF00155 Aminotransferase class I and II 36 388 2.9E-74 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 STK_03630 cf9280e21a3753c2fbf913f05035eb49 336 Gene3D G3DSA:3.30.420.40 3 307 9.0E-87 T 23-10-2018 STK_03630 cf9280e21a3753c2fbf913f05035eb49 336 TIGRFAM TIGR03722 arch_KAE1: universal archaeal protein Kae1 3 331 5.5E-145 T 23-10-2018 IPR022449 tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea GO:0000408|GO:0002949 STK_03630 cf9280e21a3753c2fbf913f05035eb49 336 Gene3D G3DSA:3.30.420.40 127 285 9.0E-87 T 23-10-2018 STK_03630 cf9280e21a3753c2fbf913f05035eb49 336 Pfam PF00814 Glycoprotease family 30 299 1.3E-78 T 23-10-2018 IPR000905 Gcp-like domain STK_03630 cf9280e21a3753c2fbf913f05035eb49 336 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 298 6.3E-77 T 23-10-2018 IPR017861 Kae1/TsaD family STK_03630 cf9280e21a3753c2fbf913f05035eb49 336 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 129 141 3.9E-34 T 23-10-2018 IPR017861 Kae1/TsaD family STK_03630 cf9280e21a3753c2fbf913f05035eb49 336 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 255 264 3.9E-34 T 23-10-2018 IPR017861 Kae1/TsaD family STK_03630 cf9280e21a3753c2fbf913f05035eb49 336 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 3.9E-34 T 23-10-2018 IPR017861 Kae1/TsaD family STK_03630 cf9280e21a3753c2fbf913f05035eb49 336 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 3.9E-34 T 23-10-2018 IPR017861 Kae1/TsaD family STK_03630 cf9280e21a3753c2fbf913f05035eb49 336 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 3.9E-34 T 23-10-2018 IPR017861 Kae1/TsaD family STK_03630 cf9280e21a3753c2fbf913f05035eb49 336 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 151 172 3.9E-34 T 23-10-2018 IPR017861 Kae1/TsaD family STK_03630 cf9280e21a3753c2fbf913f05035eb49 336 Hamap MF_01446 tRNA N6-adenosine threonylcarbamoyltransferase [kae1]. 1 332 36.954 T 23-10-2018 IPR034680 tRNA N6-adenosine threonylcarbamoyltransferase Kae1/OSGEP GO:0000408|GO:0002949 Reactome: R-HSA-6782315 STK_03630 cf9280e21a3753c2fbf913f05035eb49 336 SUPERFAMILY SSF53067 1 297 1.77E-28 T 23-10-2018 STK_07930 63528785d33bfa813c80c399e6da157a 114 SUPERFAMILY SSF81301 32 112 1.92E-21 T 23-10-2018 STK_07930 63528785d33bfa813c80c399e6da157a 114 Pfam PF01909 Nucleotidyltransferase domain 26 106 9.8E-12 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_07930 63528785d33bfa813c80c399e6da157a 114 Gene3D G3DSA:3.30.460.10 21 114 4.1E-30 T 23-10-2018 STK_24585 ca6e5410dfe394fb7de655936ec027a3 78 Gene3D G3DSA:3.40.1350.10 1 70 1.1E-6 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 STK_24585 ca6e5410dfe394fb7de655936ec027a3 78 Pfam PF01939 Endonuclease NucS 8 68 1.7E-4 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 STK_16660 ededb23287853ef49121bff04674d305 326 Gene3D G3DSA:2.102.10.10 95 317 4.1E-59 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 STK_16660 ededb23287853ef49121bff04674d305 326 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 65 97 0.0014 T 23-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal STK_16660 ededb23287853ef49121bff04674d305 326 Pfam PF00355 Rieske [2Fe-2S] domain 155 263 3.9E-8 T 23-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 STK_16660 ededb23287853ef49121bff04674d305 326 SUPERFAMILY SSF50022 97 286 3.43E-32 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 STK_16660 ededb23287853ef49121bff04674d305 326 TIGRFAM TIGR03171 soxL2: Rieske iron-sulfur protein SoxL2 2 323 2.8E-204 T 23-10-2018 IPR017586 Rieske iron-sulphur protein SoxL2 STK_05360 2bebeee2cec97239cf2abff91acb9592 391 Pfam PF12698 ABC-2 family transporter protein 17 379 1.8E-18 T 23-10-2018 STK_01610 9d45ed970606f3c1ebf6bc056dd5a95a 102 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 17 100 9.9E-6 T 23-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family STK_01610 9d45ed970606f3c1ebf6bc056dd5a95a 102 SUPERFAMILY SSF143011 19 99 9.94E-10 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily STK_01610 9d45ed970606f3c1ebf6bc056dd5a95a 102 Gene3D G3DSA:3.30.2310.20 18 102 6.1E-7 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily STK_13660 cc9a9a07347e6457acabf0fba8f36792 334 SUPERFAMILY SSF160369 10 137 1.44E-26 T 23-10-2018 STK_13660 cc9a9a07347e6457acabf0fba8f36792 334 Pfam PF00466 Ribosomal protein L10 11 106 2.2E-27 T 23-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 STK_13660 cc9a9a07347e6457acabf0fba8f36792 334 Gene3D G3DSA:3.30.70.1730 21 209 2.1E-60 T 23-10-2018 STK_13660 cc9a9a07347e6457acabf0fba8f36792 334 Hamap MF_00280 50S ribosomal protein L10 [rpl10]. 7 284 33.195 T 23-10-2018 IPR022909 50S ribosomal protein L10, archaea STK_13660 cc9a9a07347e6457acabf0fba8f36792 334 Gene3D G3DSA:3.90.105.20 108 187 2.1E-60 T 23-10-2018 STK_06450 424787019ba9d075a7754821455fa01f 230 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 4 219 3.6E-43 T 23-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 STK_06450 424787019ba9d075a7754821455fa01f 230 Pfam PF01987 Mitochondrial biogenesis AIM24 4 204 2.4E-52 T 23-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 STK_06450 424787019ba9d075a7754821455fa01f 230 SUPERFAMILY SSF51219 2 223 1.05E-65 T 23-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily STK_06450 424787019ba9d075a7754821455fa01f 230 Gene3D G3DSA:3.60.160.10 2 224 1.5E-66 T 23-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily STK_23980 78ebb8cd6a8b52de1e697567405a5a30 123 SUPERFAMILY SSF53146 1 87 4.45E-6 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily STK_00365 25f05eda629eb4e04a143542ce6295d7 84 SUPERFAMILY SSF89447 7 54 2.22E-13 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily STK_00365 25f05eda629eb4e04a143542ce6295d7 84 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 12 53 1.1E-10 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_00365 25f05eda629eb4e04a143542ce6295d7 84 ProDom PD058861 TRANSCRIPTIONAL ABRB FAMILY REGULATOR AF0476 REGULATOR 11 50 4.0E-4 T 23-10-2018 STK_00365 25f05eda629eb4e04a143542ce6295d7 84 SMART SM00966 12 58 8.6E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_00365 25f05eda629eb4e04a143542ce6295d7 84 Gene3D G3DSA:2.10.260.10 7 52 3.2E-14 T 23-10-2018 STK_00365 25f05eda629eb4e04a143542ce6295d7 84 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 11 54 1.6E-17 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 STK_16830 dcd1dd1d63d4ce3b5c7b4e8919387010 293 SUPERFAMILY SSF51713 31 200 5.1E-21 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 STK_16830 dcd1dd1d63d4ce3b5c7b4e8919387010 293 Gene3D G3DSA:3.20.20.105 28 221 3.1E-10 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 STK_16060 ace5ede07d18ffefa82873de4fd93c6c 208 Pfam PF16955 Ferrous iron uptake permease, iron-lead transporter 1 207 4.0E-109 T 23-10-2018 IPR031594 Putative iron/lead transporter STK_20980 6d04e62e1b81d1a86727c1d809e099be 211 PIRSF PIRSF037213 1 211 2.3E-76 T 23-10-2018 IPR017139 Uncharacterised conserved protein UCP037213 STK_20980 6d04e62e1b81d1a86727c1d809e099be 211 Gene3D G3DSA:1.10.10.10 12 114 9.9E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_20980 6d04e62e1b81d1a86727c1d809e099be 211 Pfam PF10007 Uncharacterized protein conserved in archaea (DUF2250) 113 203 1.2E-32 T 23-10-2018 IPR019254 Protein of unknown function DUF2250 STK_20980 6d04e62e1b81d1a86727c1d809e099be 211 Pfam PF10007 Uncharacterized protein conserved in archaea (DUF2250) 12 101 1.4E-37 T 23-10-2018 IPR019254 Protein of unknown function DUF2250 STK_20980 6d04e62e1b81d1a86727c1d809e099be 211 SUPERFAMILY SSF46785 1 102 8.92E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_09794 a94fe7cee0a7b2695b382814e8db72d7 94 Gene3D G3DSA:1.10.10.10 3 93 1.1E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_09794 a94fe7cee0a7b2695b382814e8db72d7 94 Pfam PF14947 Winged helix-turn-helix 4 79 4.1E-28 T 23-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain STK_09794 a94fe7cee0a7b2695b382814e8db72d7 94 SUPERFAMILY SSF46785 6 91 3.45E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_19540 c48bd973219167403508177a587afd51 145 Gene3D G3DSA:3.40.50.150 1 109 1.7E-6 T 23-10-2018 STK_19540 c48bd973219167403508177a587afd51 145 SUPERFAMILY SSF53335 2 93 1.33E-6 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_23510 2b13c93b293726754d924d0a4aba9d03 375 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 76 207 4.0E-12 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like STK_06360 2c630f6ed0c6ddf5b1051f7d916f486c 128 Gene3D G3DSA:1.10.10.10 2 90 1.2E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_06360 2c630f6ed0c6ddf5b1051f7d916f486c 128 SUPERFAMILY SSF46785 4 80 1.55E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_06360 2c630f6ed0c6ddf5b1051f7d916f486c 128 PIRSF PIRSF032673 1 128 4.0E-57 T 23-10-2018 IPR014572 Uncharacterised conserved protein UCP032673 STK_24400 3df922a4b7cc02429112ae0182b96b24 514 SUPERFAMILY SSF56112 210 509 1.37E-37 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily STK_24400 3df922a4b7cc02429112ae0182b96b24 514 SUPERFAMILY SSF101424 102 200 7.98E-8 T 23-10-2018 IPR036321 Hypothetical protein ST1625 STK_24400 3df922a4b7cc02429112ae0182b96b24 514 SMART SM00220 214 509 3.5E-15 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 STK_24400 3df922a4b7cc02429112ae0182b96b24 514 Gene3D G3DSA:1.10.510.10 211 513 5.9E-31 T 23-10-2018 STK_24400 3df922a4b7cc02429112ae0182b96b24 514 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 353 365 - T 23-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 STK_24400 3df922a4b7cc02429112ae0182b96b24 514 Pfam PF00069 Protein kinase domain 220 506 1.1E-21 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 STK_01830 40400d287f3c0e1c07de6425c947d646 262 Pfam PF01925 Sulfite exporter TauE/SafE 15 252 1.2E-38 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 STK_06890 848a75015f2cc13a00888a5a20c5b7ca 122 Pfam PF05168 HEPN domain 4 119 1.0E-33 T 23-10-2018 IPR007842 HEPN domain STK_06890 848a75015f2cc13a00888a5a20c5b7ca 122 SUPERFAMILY SSF81593 2 119 1.1E-43 T 23-10-2018 STK_06890 848a75015f2cc13a00888a5a20c5b7ca 122 Gene3D G3DSA:1.20.120.330 1 122 5.4E-39 T 23-10-2018 STK_06890 848a75015f2cc13a00888a5a20c5b7ca 122 SMART SM00748 8 113 5.2E-45 T 23-10-2018 IPR007842 HEPN domain STK_11340 4ac3a626a0c81d236087299597e43c31 103 Pfam PF02426 Muconolactone delta-isomerase 2 93 5.1E-20 T 23-10-2018 IPR026029 Muconolactone isomerase domain KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 STK_11340 4ac3a626a0c81d236087299597e43c31 103 Gene3D G3DSA:3.30.70.1060 2 96 4.3E-22 T 23-10-2018 STK_11340 4ac3a626a0c81d236087299597e43c31 103 SUPERFAMILY SSF54909 2 98 1.29E-26 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel STK_11730 fb607612f93a21014e600e8e5db8ef9e 146 Gene3D G3DSA:1.20.120.520 4 132 4.4E-9 T 23-10-2018 STK_11730 fb607612f93a21014e600e8e5db8ef9e 146 Pfam PF01814 Hemerythrin HHE cation binding domain 6 113 6.3E-12 T 23-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 STK_15340 686b87373ebee4cbff43fa6f85b67b91 347 SUPERFAMILY SSF47240 5 132 7.61E-9 T 23-10-2018 IPR009078 Ferritin-like superfamily STK_15340 686b87373ebee4cbff43fa6f85b67b91 347 Pfam PF01988 VIT family 138 338 4.1E-39 T 23-10-2018 IPR008217 Ccc1 family STK_11510 d61d3eac568c2246b496cd67c7c403df 551 Pfam PF07728 AAA domain (dynein-related subfamily) 263 439 4.0E-13 T 23-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 STK_11510 d61d3eac568c2246b496cd67c7c403df 551 SUPERFAMILY SSF52540 252 487 4.71E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_11510 d61d3eac568c2246b496cd67c7c403df 551 SMART SM00382 260 445 3.0E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_17050 e7b6e3b184846870ecb741233bc06467 281 SUPERFAMILY SSF56529 61 278 5.76E-75 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 STK_17050 e7b6e3b184846870ecb741233bc06467 281 Gene3D G3DSA:3.90.850.10 66 281 1.7E-80 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 STK_17050 e7b6e3b184846870ecb741233bc06467 281 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 70 278 4.1E-68 T 23-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 STK_23210 2ff0c68c1d9e0689196ff6a968539ba5 247 Pfam PF01988 VIT family 21 232 2.9E-47 T 23-10-2018 IPR008217 Ccc1 family STK_18900 232846d7c97588f23c25f6e3e6b831a4 128 SUPERFAMILY SSF46785 17 119 3.69E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_18900 232846d7c97588f23c25f6e3e6b831a4 128 SMART SM00347 21 115 0.0061 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 STK_18900 232846d7c97588f23c25f6e3e6b831a4 128 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 22 97 2.3E-14 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal STK_18900 232846d7c97588f23c25f6e3e6b831a4 128 Gene3D G3DSA:1.10.10.10 14 117 2.8E-31 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_03620 b5b8ce15cae1619be27c00b54b5bc43a 120 Hamap MF_00545 30S ribosomal protein S24e [rps24e]. 7 114 17.335 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_03620 b5b8ce15cae1619be27c00b54b5bc43a 120 ProDom PD006052 RIBOSOMAL S24 40S RIBONUCLEOPROTEIN S24E 30S S24 CDNA RIKEN ACETYLATION 25 93 1.0E-33 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_03620 b5b8ce15cae1619be27c00b54b5bc43a 120 Gene3D G3DSA:3.30.70.330 6 113 4.2E-23 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily STK_03620 b5b8ce15cae1619be27c00b54b5bc43a 120 ProSitePatterns PS00529 Ribosomal protein S24e signature. 74 96 - T 23-10-2018 IPR018098 Ribosomal S24e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_03620 b5b8ce15cae1619be27c00b54b5bc43a 120 Pfam PF01282 Ribosomal protein S24e 35 111 3.8E-18 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_03620 b5b8ce15cae1619be27c00b54b5bc43a 120 SUPERFAMILY SSF54189 17 115 9.35E-26 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 STK_13880 e6defb3cbac4ae315b3db1b5265d003d 454 Pfam PF13193 AMP-binding enzyme C-terminal domain 386 453 2.1E-10 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain STK_13880 e6defb3cbac4ae315b3db1b5265d003d 454 Gene3D G3DSA:3.40.50.12780 1 371 2.6E-72 T 23-10-2018 STK_13880 e6defb3cbac4ae315b3db1b5265d003d 454 Gene3D G3DSA:3.30.300.30 372 453 5.4E-14 T 23-10-2018 STK_13880 e6defb3cbac4ae315b3db1b5265d003d 454 Pfam PF00501 AMP-binding enzyme 9 376 1.9E-61 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 STK_13880 e6defb3cbac4ae315b3db1b5265d003d 454 SUPERFAMILY SSF56801 2 453 2.22E-88 T 23-10-2018 STK_15570 3afb73703cec3f0457197dd1b218a885 433 Pfam PF17231 Family of unknown function (DUF5305) 258 430 2.7E-12 T 23-10-2018 IPR035185 Protein of unknown function DUF5305 STK_10310 4525efddeee81074992c63c790f6c490 378 PRINTS PR01466 Bacterial arginine deiminase signature 3 23 3.4E-14 T 23-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 STK_10310 4525efddeee81074992c63c790f6c490 378 PRINTS PR01466 Bacterial arginine deiminase signature 313 330 3.4E-14 T 23-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 STK_10310 4525efddeee81074992c63c790f6c490 378 PRINTS PR01466 Bacterial arginine deiminase signature 333 347 3.4E-14 T 23-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 STK_10310 4525efddeee81074992c63c790f6c490 378 PRINTS PR01466 Bacterial arginine deiminase signature 135 153 3.4E-14 T 23-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 STK_10310 4525efddeee81074992c63c790f6c490 378 Gene3D G3DSA:3.75.10.10 7 376 3.5E-77 T 23-10-2018 STK_10310 4525efddeee81074992c63c790f6c490 378 Pfam PF02274 Amidinotransferase 21 375 1.6E-51 T 23-10-2018 STK_10310 4525efddeee81074992c63c790f6c490 378 SUPERFAMILY SSF55909 2 377 2.75E-84 T 23-10-2018 STK_10310 4525efddeee81074992c63c790f6c490 378 Gene3D G3DSA:1.10.3930.10 69 135 3.5E-77 T 23-10-2018 STK_05560 c9518457f60325e6f77c22fbc7282bb5 170 TIGRFAM TIGR00340 zpr1_rel: zinc finger protein ZPR1 homolog 14 164 1.2E-43 T 23-10-2018 IPR004470 Zinc finger, ZPR1-type, subgroup GO:0008270 STK_05560 c9518457f60325e6f77c22fbc7282bb5 170 TIGRFAM TIGR00310 ZPR1_znf: ZPR1 zinc finger domain 14 165 3.5E-30 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 STK_05560 c9518457f60325e6f77c22fbc7282bb5 170 Pfam PF03367 ZPR1 zinc-finger domain 13 155 8.6E-31 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 STK_05560 c9518457f60325e6f77c22fbc7282bb5 170 SMART SM00709 12 156 7.0E-30 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 STK_05560 c9518457f60325e6f77c22fbc7282bb5 170 Gene3D G3DSA:2.60.120.1040 61 169 1.9E-18 T 23-10-2018 STK_15210 38177f68616ef09471a20316faf8bfc0 127 Pfam PF08753 NikR C terminal nickel binding domain 52 121 3.4E-18 T 23-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal STK_15210 38177f68616ef09471a20316faf8bfc0 127 SUPERFAMILY SSF55021 51 123 5.95E-17 T 23-10-2018 STK_15210 38177f68616ef09471a20316faf8bfc0 127 Gene3D G3DSA:3.30.70.1150 28 124 4.1E-20 T 23-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal STK_15210 38177f68616ef09471a20316faf8bfc0 127 SUPERFAMILY SSF47598 4 46 1.7E-6 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 STK_15210 38177f68616ef09471a20316faf8bfc0 127 Pfam PF10929 Protein of unknown function (DUF2811) 7 48 8.9E-6 T 23-10-2018 IPR021231 Protein of unknown function DUF2811 STK_23750 e219f26a9a4982aeef112fb3f58fb73b 121 Pfam PF07843 Protein of unknown function (DUF1634) 7 114 4.5E-28 T 23-10-2018 IPR012861 Protein of unknown function DUF1634 STK_15080 3c9d22221b24bc3eec606f9bb84e4d04 187 SUPERFAMILY SSF51182 59 181 1.72E-31 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily STK_15080 3c9d22221b24bc3eec606f9bb84e4d04 187 Gene3D G3DSA:2.60.120.10 42 187 4.1E-33 T 23-10-2018 IPR014710 RmlC-like jelly roll fold STK_15080 3c9d22221b24bc3eec606f9bb84e4d04 187 SMART SM00835 78 187 2.5E-4 T 23-10-2018 IPR006045 Cupin 1 GO:0045735 STK_15080 3c9d22221b24bc3eec606f9bb84e4d04 187 Pfam PF07883 Cupin domain 99 167 8.4E-14 T 23-10-2018 IPR013096 Cupin 2, conserved barrel STK_16460 9d19f56fbed30a21694eb4a6e0ddc871 260 Gene3D G3DSA:3.40.50.300 26 260 8.6E-11 T 23-10-2018 STK_16460 9d19f56fbed30a21694eb4a6e0ddc871 260 SUPERFAMILY SSF52540 11 185 5.78E-9 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_22490 19b5f1ce90b7f1d2eb13cbdac9bcc469 605 Gene3D G3DSA:3.40.50.300 153 272 5.1E-13 T 23-10-2018 STK_22490 19b5f1ce90b7f1d2eb13cbdac9bcc469 605 SUPERFAMILY SSF52540 145 598 6.82E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_22490 19b5f1ce90b7f1d2eb13cbdac9bcc469 605 Gene3D G3DSA:3.40.50.300 395 594 1.7E-19 T 23-10-2018 STK_22490 19b5f1ce90b7f1d2eb13cbdac9bcc469 605 SMART SM00382 189 551 6.8E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_22490 19b5f1ce90b7f1d2eb13cbdac9bcc469 605 Pfam PF01935 Domain of unknown function DUF87 170 459 3.0E-16 T 23-10-2018 IPR002789 Helicase HerA, central domain STK_02080 02ffd117571cb7b8f5bfd7e5aebe519a 121 Gene3D G3DSA:3.40.1490.10 2 121 1.5E-50 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 STK_02080 02ffd117571cb7b8f5bfd7e5aebe519a 121 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 4 121 2.9E-45 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 STK_02080 02ffd117571cb7b8f5bfd7e5aebe519a 121 Hamap MF_00628 Peptidyl-tRNA hydrolase [pth]. 3 121 29.616 T 23-10-2018 IPR034759 Peptidyl-tRNA hydrolase, archaea GO:0004045 MetaCyc: PWY-6308 STK_02080 02ffd117571cb7b8f5bfd7e5aebe519a 121 TIGRFAM TIGR00283 arch_pth2: peptidyl-tRNA hydrolase 4 121 3.0E-43 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 STK_02080 02ffd117571cb7b8f5bfd7e5aebe519a 121 SUPERFAMILY SSF102462 3 121 7.85E-45 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 STK_09850 f01c272d21c8ceec450c44773b357f3b 251 SUPERFAMILY SSF52540 1 237 2.29E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_09850 f01c272d21c8ceec450c44773b357f3b 251 Gene3D G3DSA:3.40.50.300 2 249 7.7E-19 T 23-10-2018 STK_09850 f01c272d21c8ceec450c44773b357f3b 251 Pfam PF13614 AAA domain 3 128 4.3E-10 T 23-10-2018 IPR025669 AAA domain STK_10180 8fd64e8a75400e20e5562f78d516b447 264 Gene3D G3DSA:3.60.110.10 1 263 1.0E-70 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily STK_10180 8fd64e8a75400e20e5562f78d516b447 264 Pfam PF00795 Carbon-nitrogen hydrolase 2 248 2.4E-47 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 STK_10180 8fd64e8a75400e20e5562f78d516b447 264 SUPERFAMILY SSF56317 1 257 5.36E-65 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily STK_10540 5ad09f510f08b349e52179fbaa752b6b 225 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 4 213 41.046 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein STK_10540 5ad09f510f08b349e52179fbaa752b6b 225 Gene3D G3DSA:2.40.50.580 1 75 2.1E-9 T 23-10-2018 STK_10540 5ad09f510f08b349e52179fbaa752b6b 225 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 2 209 2.5E-45 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein STK_10540 5ad09f510f08b349e52179fbaa752b6b 225 Gene3D G3DSA:3.40.1350.60 76 213 4.7E-38 T 23-10-2018 STK_10540 5ad09f510f08b349e52179fbaa752b6b 225 Pfam PF03749 Sugar fermentation stimulation protein 17 203 1.8E-54 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein STK_14740 d527b7941a0206001791e443ce96b2e7 202 Pfam PF01914 MarC family integral membrane protein 6 198 5.7E-30 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 STK_13930 15b0ed7feeced0a11601104ec50639a5 284 Gene3D G3DSA:1.10.443.10 112 283 1.4E-52 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 STK_13930 15b0ed7feeced0a11601104ec50639a5 284 SUPERFAMILY SSF56349 15 279 8.24E-52 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 STK_13930 15b0ed7feeced0a11601104ec50639a5 284 Gene3D G3DSA:1.10.150.130 11 109 7.4E-8 T 23-10-2018 IPR010998 Integrase/recombinase, N-terminal STK_13930 15b0ed7feeced0a11601104ec50639a5 284 Pfam PF00589 Phage integrase family 121 270 1.3E-38 T 23-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 STK_13930 15b0ed7feeced0a11601104ec50639a5 284 Hamap MF_02055 Tyrosine recombinase XerA [xerA]. 11 283 50.535 T 23-10-2018 IPR033686 Tyrosine recombinase XerA STK_25520 41a28cc6ae0dcf686faf3fe4aed38747 436 Pfam PF01385 Probable transposase 171 286 2.0E-36 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 STK_25520 41a28cc6ae0dcf686faf3fe4aed38747 436 Pfam PF07282 Putative transposase DNA-binding domain 301 369 2.9E-19 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_25520 41a28cc6ae0dcf686faf3fe4aed38747 436 SUPERFAMILY SSF53098 258 332 2.85E-5 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily STK_25520 41a28cc6ae0dcf686faf3fe4aed38747 436 Gene3D G3DSA:3.30.420.140 239 347 1.4E-5 T 23-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 STK_23160 4ae16afeaea0318f3f51bb8cbceab603 627 Gene3D G3DSA:3.30.70.20 275 346 1.9E-8 T 23-10-2018 STK_23160 4ae16afeaea0318f3f51bb8cbceab603 627 PIRSF PIRSF032862 1 627 0.0 T 23-10-2018 IPR017010 Uncharacterised conserved protein UCP032862, iron-sulphur-binding domain-type, SSO0018 STK_23160 4ae16afeaea0318f3f51bb8cbceab603 627 Pfam PF13183 4Fe-4S dicluster domain 289 345 1.4E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_23160 4ae16afeaea0318f3f51bb8cbceab603 627 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 292 303 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_23160 4ae16afeaea0318f3f51bb8cbceab603 627 SUPERFAMILY SSF46548 265 352 2.41E-14 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 STK_23160 4ae16afeaea0318f3f51bb8cbceab603 627 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 332 343 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site STK_05270 4f35a61e3fd4192615270bce8d229521 236 Gene3D G3DSA:3.10.20.30 1 85 1.2E-13 T 23-10-2018 IPR012675 Beta-grasp domain superfamily STK_05270 4f35a61e3fd4192615270bce8d229521 236 Pfam PF02597 ThiS family 6 85 7.0E-10 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 STK_05270 4f35a61e3fd4192615270bce8d229521 236 SUPERFAMILY SSF54285 3 85 9.91E-12 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp STK_05270 4f35a61e3fd4192615270bce8d229521 236 Gene3D G3DSA:3.90.1170.40 87 231 3.5E-31 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 STK_05270 4f35a61e3fd4192615270bce8d229521 236 Pfam PF02391 MoaE protein 99 203 6.6E-19 T 23-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 STK_05270 4f35a61e3fd4192615270bce8d229521 236 SUPERFAMILY SSF54690 94 225 5.62E-31 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 STK_05270 4f35a61e3fd4192615270bce8d229521 236 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 3 85 1.4E-28 T 23-10-2018 IPR010038 MoaD, archaeal-type STK_02360 1d96e320dc96cd18d7cfea8b18561c34 103 SMART SM00418 13 84 8.9E-4 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 STK_02360 1d96e320dc96cd18d7cfea8b18561c34 103 Gene3D G3DSA:1.10.10.10 3 90 8.2E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_02360 1d96e320dc96cd18d7cfea8b18561c34 103 Pfam PF01022 Bacterial regulatory protein, arsR family 23 65 7.4E-13 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 STK_02360 1d96e320dc96cd18d7cfea8b18561c34 103 SUPERFAMILY SSF46785 7 91 3.94E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_15180 921fee4047c1960331f338ee219b4761 301 Pfam PF01040 UbiA prenyltransferase family 38 284 6.4E-50 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 STK_15180 921fee4047c1960331f338ee219b4761 301 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 18 300 16.805 T 23-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 STK_15180 921fee4047c1960331f338ee219b4761 301 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 21 298 1.6E-84 T 23-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 STK_15180 921fee4047c1960331f338ee219b4761 301 Gene3D G3DSA:1.10.357.140 28 198 4.0E-15 T 23-10-2018 STK_16420 7c6f404e11c2387b18b6f5774d10e585 134 Pfam PF01850 PIN domain 3 112 7.5E-15 T 23-10-2018 IPR002716 PIN domain STK_16420 7c6f404e11c2387b18b6f5774d10e585 134 Gene3D G3DSA:3.40.50.1010 3 122 2.0E-10 T 23-10-2018 STK_16420 7c6f404e11c2387b18b6f5774d10e585 134 SUPERFAMILY SSF88723 1 128 1.82E-16 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_12140 9f69b3cdcd23b65362f1b2389ebb8770 266 Gene3D G3DSA:1.10.10.10 210 266 7.9E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_12140 9f69b3cdcd23b65362f1b2389ebb8770 266 Pfam PF03357 Snf7 27 193 3.0E-8 T 23-10-2018 IPR005024 Snf7 family GO:0007034 STK_16590 c6f934e5edf28ebe1f04fb85bd8dc9e9 502 Gene3D G3DSA:1.20.140.10 278 479 1.6E-71 T 23-10-2018 STK_16590 c6f934e5edf28ebe1f04fb85bd8dc9e9 502 Gene3D G3DSA:2.40.110.10 147 275 7.6E-40 T 23-10-2018 STK_16590 c6f934e5edf28ebe1f04fb85bd8dc9e9 502 Gene3D G3DSA:1.10.3140.10 2 145 1.4E-47 T 23-10-2018 STK_16590 c6f934e5edf28ebe1f04fb85bd8dc9e9 502 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 5 274 3.2E-96 T 23-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal STK_16590 c6f934e5edf28ebe1f04fb85bd8dc9e9 502 SUPERFAMILY SSF47203 265 477 1.76E-66 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 STK_16590 c6f934e5edf28ebe1f04fb85bd8dc9e9 502 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 282 477 1.7E-65 T 23-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal STK_16590 c6f934e5edf28ebe1f04fb85bd8dc9e9 502 PIRSF PIRSF000331 1 488 2.1E-179 T 23-10-2018 IPR004925 HpaB/PvcC/4-BUDH STK_16590 c6f934e5edf28ebe1f04fb85bd8dc9e9 502 SUPERFAMILY SSF56645 3 274 3.14E-79 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 STK_19600 b13aa37e850ab996f3e7e088afd94f0d 304 SUPERFAMILY SSF53448 3 261 2.63E-21 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_19600 b13aa37e850ab996f3e7e088afd94f0d 304 Gene3D G3DSA:3.90.550.10 2 197 3.1E-14 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_19600 b13aa37e850ab996f3e7e088afd94f0d 304 Pfam PF00535 Glycosyl transferase family 2 3 128 2.6E-13 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 STK_05200 36a8e7f8e4faca77fbe38f0881584fad 359 SUPERFAMILY SSF81271 280 358 7.46E-19 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 STK_05200 36a8e7f8e4faca77fbe38f0881584fad 359 Pfam PF02824 TGS domain 286 357 9.2E-23 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 STK_05200 36a8e7f8e4faca77fbe38f0881584fad 359 Gene3D G3DSA:3.10.20.30 278 359 1.0E-30 T 23-10-2018 IPR012675 Beta-grasp domain superfamily STK_15640 84d7d56aa669338449633a65b8368800 523 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 38 462 3.6E-61 T 23-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 STK_15640 84d7d56aa669338449633a65b8368800 523 Gene3D G3DSA:1.10.4160.10 22 513 1.2E-97 T 23-10-2018 IPR038271 Purine-cytosine permease superfamily STK_06020 a709bf91e7b171d78bbf23f4a5943b25 389 Gene3D G3DSA:3.40.640.10 18 267 3.7E-114 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 STK_06020 a709bf91e7b171d78bbf23f4a5943b25 389 SUPERFAMILY SSF53383 6 371 9.32E-93 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase STK_06020 a709bf91e7b171d78bbf23f4a5943b25 389 Pfam PF00266 Aminotransferase class-V 27 335 2.7E-37 T 23-10-2018 IPR000192 Aminotransferase class V domain STK_06020 a709bf91e7b171d78bbf23f4a5943b25 389 PIRSF PIRSF000524 1 389 6.2E-97 T 23-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 STK_06020 a709bf91e7b171d78bbf23f4a5943b25 389 Gene3D G3DSA:3.90.1150.10 13 381 3.7E-114 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 STK_06020 a709bf91e7b171d78bbf23f4a5943b25 389 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 184 204 - T 23-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site STK_09930 b4145a9e7697051d0dd53957403d4b5f 343 Pfam PF04454 Encapsulating protein for peroxidase 198 299 4.1E-12 T 23-10-2018 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 STK_09930 b4145a9e7697051d0dd53957403d4b5f 343 Gene3D G3DSA:1.20.1260.10 3 75 1.5E-5 T 23-10-2018 IPR012347 Ferritin-like STK_09930 b4145a9e7697051d0dd53957403d4b5f 343 Gene3D G3DSA:3.30.2320.10 216 312 1.9E-15 T 23-10-2018 STK_09930 b4145a9e7697051d0dd53957403d4b5f 343 SUPERFAMILY SSF47240 8 83 1.33E-14 T 23-10-2018 IPR009078 Ferritin-like superfamily STK_16780 cd91925749f26c967a20be1ede9b8cfc 842 SUPERFAMILY SSF82866 291 486 6.28E-27 T 23-10-2018 STK_16780 cd91925749f26c967a20be1ede9b8cfc 842 Pfam PF03176 MMPL family 289 508 1.2E-39 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 STK_16780 cd91925749f26c967a20be1ede9b8cfc 842 Pfam PF03176 MMPL family 656 831 5.8E-23 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 STK_16780 cd91925749f26c967a20be1ede9b8cfc 842 Gene3D G3DSA:1.20.1640.10 283 486 6.5E-9 T 23-10-2018 STK_16780 cd91925749f26c967a20be1ede9b8cfc 842 SUPERFAMILY SSF82866 647 830 2.35E-15 T 23-10-2018 STK_20290 bfc4d266ec2c542576d8c1d05f591471 178 PIRSF PIRSF024051 2 178 2.3E-57 T 23-10-2018 IPR018036 Protein of unknown function DUF429, subgroup STK_24310 c52ed6c8d0f2c28d6d5a3adae679f2c9 381 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 243 324 3.2E-24 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_24310 c52ed6c8d0f2c28d6d5a3adae679f2c9 381 Pfam PF07282 Putative transposase DNA-binding domain 297 363 4.4E-21 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_08025 fd5bea19af609b09682cc41350c77e44 93 Pfam PF13463 Winged helix DNA-binding domain 4 65 2.6E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 STK_08025 fd5bea19af609b09682cc41350c77e44 93 Gene3D G3DSA:1.10.10.10 1 85 3.6E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_08025 fd5bea19af609b09682cc41350c77e44 93 SUPERFAMILY SSF46785 2 83 2.29E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_07210 2964dedfdb5c44850adf540b2b9151c4 154 PIRSF PIRSF000239 1 153 6.0E-28 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 STK_07210 2964dedfdb5c44850adf540b2b9151c4 154 SUPERFAMILY SSF52833 2 146 1.97E-48 T 23-10-2018 IPR036249 Thioredoxin-like superfamily STK_07210 2964dedfdb5c44850adf540b2b9151c4 154 Gene3D G3DSA:3.40.30.10 1 154 1.4E-50 T 23-10-2018 STK_07210 2964dedfdb5c44850adf540b2b9151c4 154 Pfam PF00578 AhpC/TSA family 3 124 1.8E-35 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 STK_19110 4e716a1c9824337c37843bd4d6b4b222 332 Pfam PF01944 Stage II sporulation protein M 16 164 5.0E-13 T 23-10-2018 IPR002798 Stage II sporulation protein M-like STK_10440 9c70fb81a7151b8b33df61306b73a905 134 SUPERFAMILY SSF54637 1 131 3.44E-33 T 23-10-2018 IPR029069 HotDog domain superfamily STK_10440 9c70fb81a7151b8b33df61306b73a905 134 Pfam PF13279 Thioesterase-like superfamily 12 130 6.7E-8 T 23-10-2018 STK_10440 9c70fb81a7151b8b33df61306b73a905 134 Gene3D G3DSA:3.10.129.10 1 133 2.9E-31 T 23-10-2018 STK_12920 8bcf7d4851551ec15db1c194192c2b65 483 Gene3D G3DSA:3.90.1860.10 2 483 1.0E-196 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 STK_12920 8bcf7d4851551ec15db1c194192c2b65 483 SUPERFAMILY SSF103365 5 483 1.83E-172 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 STK_12920 8bcf7d4851551ec15db1c194192c2b65 483 Pfam PF01139 tRNA-splicing ligase RtcB 48 483 9.8E-162 T 23-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 STK_11400 97dd8cfcf5c5a9a87db45bb1cc49a5fb 242 Pfam PF13938 Putative heavy-metal chelation 4 81 2.4E-21 T 23-10-2018 IPR025251 Domain of unknown function DUF4213 STK_11400 97dd8cfcf5c5a9a87db45bb1cc49a5fb 242 Gene3D G3DSA:3.40.50.11590 94 207 1.6E-47 T 23-10-2018 STK_11400 97dd8cfcf5c5a9a87db45bb1cc49a5fb 242 Gene3D G3DSA:3.30.390.100 7 212 1.6E-47 T 23-10-2018 STK_11400 97dd8cfcf5c5a9a87db45bb1cc49a5fb 242 SUPERFAMILY SSF159713 7 232 1.22E-57 T 23-10-2018 STK_11400 97dd8cfcf5c5a9a87db45bb1cc49a5fb 242 Pfam PF04016 Putative heavy-metal chelation 92 226 1.1E-43 T 23-10-2018 IPR007161 Putative heavy-metal chelation domain STK_22160 fe3af4a510ea7e82dbb1fef84942bc03 128 Gene3D G3DSA:1.20.58.1610 3 124 7.0E-6 T 23-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_22160 fe3af4a510ea7e82dbb1fef84942bc03 128 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 29 118 2.4E-6 T 23-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_04780 dc5318e8fdb4bf3688edad4ce3aa8ee4 396 ProSitePatterns PS00571 Amidases signature. 110 141 - T 23-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 STK_04780 dc5318e8fdb4bf3688edad4ce3aa8ee4 396 SUPERFAMILY SSF75304 6 390 1.44E-102 T 23-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 STK_04780 dc5318e8fdb4bf3688edad4ce3aa8ee4 396 Gene3D G3DSA:3.90.1300.10 5 393 1.6E-105 T 23-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 STK_04780 dc5318e8fdb4bf3688edad4ce3aa8ee4 396 Pfam PF01425 Amidase 21 192 7.3E-64 T 23-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 STK_04780 dc5318e8fdb4bf3688edad4ce3aa8ee4 396 Pfam PF01425 Amidase 251 382 1.8E-16 T 23-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 STK_08930 68fa9f89797e17b698fd5580cf4b22a9 466 SUPERFAMILY SSF53756 3 465 9.42E-84 T 23-10-2018 STK_08930 68fa9f89797e17b698fd5580cf4b22a9 466 Pfam PF00534 Glycosyl transferases group 1 268 410 2.0E-15 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 STK_08930 68fa9f89797e17b698fd5580cf4b22a9 466 Gene3D G3DSA:3.40.50.2000 270 450 2.5E-18 T 23-10-2018 STK_08930 68fa9f89797e17b698fd5580cf4b22a9 466 Gene3D G3DSA:3.40.50.2000 2 269 8.3E-7 T 23-10-2018 STK_17420 3eec005e0d166d9d1bd74e007f6ccc40 176 Pfam PF06197 Protein of unknown function (DUF998) 15 169 4.4E-19 T 23-10-2018 IPR009339 Protein of unknown function DUF998 STK_05650 04888480bb06032126cbdc1c1ecafdab 275 Pfam PF01380 SIS domain 65 137 3.7E-8 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 STK_05650 04888480bb06032126cbdc1c1ecafdab 275 Gene3D G3DSA:3.40.50.10490 4 146 1.9E-16 T 23-10-2018 STK_05650 04888480bb06032126cbdc1c1ecafdab 275 Gene3D G3DSA:3.40.50.10490 147 251 6.9E-8 T 23-10-2018 STK_05650 04888480bb06032126cbdc1c1ecafdab 275 SUPERFAMILY SSF53697 17 221 8.09E-28 T 23-10-2018 STK_13177 e7d52e812d5f8167a84737faead8e349 94 SUPERFAMILY SSF46785 10 89 3.58E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_13177 e7d52e812d5f8167a84737faead8e349 94 Pfam PF02082 Transcriptional regulator 12 56 4.6E-5 T 23-10-2018 IPR000944 Transcription regulator Rrf2-type STK_13177 e7d52e812d5f8167a84737faead8e349 94 Gene3D G3DSA:1.10.10.10 7 94 4.7E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_06510 5fd446e8739905d0214a4f26ef2b91ee 375 Gene3D G3DSA:3.50.50.60 109 252 1.1E-60 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_06510 5fd446e8739905d0214a4f26ef2b91ee 375 SUPERFAMILY SSF51905 2 301 8.42E-10 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_06510 5fd446e8739905d0214a4f26ef2b91ee 375 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 291 6.0E-21 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 STK_06510 5fd446e8739905d0214a4f26ef2b91ee 375 Gene3D G3DSA:3.50.50.60 3 304 1.1E-60 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_06510 5fd446e8739905d0214a4f26ef2b91ee 375 SUPERFAMILY SSF51905 1 136 2.42E-19 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_07170 2a96564410062c595f202b6896d04eda 162 Pfam PF05942 Archaeal PaREP1/PaREP8 family 23 150 2.2E-28 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_22360 f05e21cfa265f4398db648caf0b9a262 137 SUPERFAMILY SSF47979 69 136 4.05E-19 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 STK_22360 f05e21cfa265f4398db648caf0b9a262 137 SUPERFAMILY SSF46785 16 91 3.84E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_22360 f05e21cfa265f4398db648caf0b9a262 137 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 69 136 1.2E-21 T 23-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 STK_22360 f05e21cfa265f4398db648caf0b9a262 137 SMART SM00529 31 128 1.7E-14 T 23-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 STK_22360 f05e21cfa265f4398db648caf0b9a262 137 Gene3D G3DSA:1.10.10.10 3 137 8.1E-41 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_11560 19283de85977a67e876cf07d0916520f 100 SUPERFAMILY SSF46689 49 97 3.67E-9 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 STK_11560 19283de85977a67e876cf07d0916520f 100 Gene3D G3DSA:1.10.10.10 48 96 3.1E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_11560 19283de85977a67e876cf07d0916520f 100 Pfam PF13384 Homeodomain-like domain 52 90 1.8E-8 T 23-10-2018 STK_05510 fefb50335eff5c745197d83ae6deb421 176 Pfam PF00156 Phosphoribosyl transferase domain 15 151 1.6E-23 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 STK_05510 fefb50335eff5c745197d83ae6deb421 176 Gene3D G3DSA:3.40.50.2020 1 176 9.2E-52 T 23-10-2018 STK_05510 fefb50335eff5c745197d83ae6deb421 176 SUPERFAMILY SSF53271 5 167 2.88E-34 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like STK_04870 748bcd54356c03f59f4722bb327baa20 283 Pfam PF00348 Polyprenyl synthetase 30 209 1.2E-35 T 23-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 STK_04870 748bcd54356c03f59f4722bb327baa20 283 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 192 204 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site STK_04870 748bcd54356c03f59f4722bb327baa20 283 SUPERFAMILY SSF48576 13 259 9.25E-44 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily STK_04870 748bcd54356c03f59f4722bb327baa20 283 Gene3D G3DSA:1.10.600.10 1 283 7.2E-71 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily STK_09535 a83f7ea0d19c6b92aedc7dbb5d0c759a 79 Pfam PF07935 ORF D-335-like protein 5 68 2.3E-25 T 23-10-2018 IPR012922 ORF D-335-like STK_15270 76b8677185b05d022e44f468f107bad5 173 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 73 157 1.1E-20 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_15270 76b8677185b05d022e44f468f107bad5 173 Gene3D G3DSA:3.40.50.12280 6 173 1.1E-53 T 23-10-2018 STK_15270 76b8677185b05d022e44f468f107bad5 173 SUPERFAMILY SSF56770 26 167 2.62E-51 T 23-10-2018 STK_15270 76b8677185b05d022e44f468f107bad5 173 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 28 164 4.0E-49 T 23-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 STK_06160 812fb348516ac46f2ee2876e1fdebfb5 127 Pfam PF02635 DsrE/DsrF-like family 26 107 3.4E-7 T 23-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein STK_06160 812fb348516ac46f2ee2876e1fdebfb5 127 SUPERFAMILY SSF75169 1 115 9.42E-13 T 23-10-2018 IPR027396 DsrEFH-like STK_06160 812fb348516ac46f2ee2876e1fdebfb5 127 Gene3D G3DSA:3.40.1260.10 1 126 4.5E-16 T 23-10-2018 IPR027396 DsrEFH-like STK_08400 f16fa83497c4ddad4f90f718258d5d33 329 Gene3D G3DSA:3.40.50.1980 176 307 1.4E-18 T 23-10-2018 STK_08400 f16fa83497c4ddad4f90f718258d5d33 329 Gene3D G3DSA:3.40.50.1980 31 172 5.1E-19 T 23-10-2018 STK_08400 f16fa83497c4ddad4f90f718258d5d33 329 Pfam PF01497 Periplasmic binding protein 48 280 1.6E-20 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain STK_08400 f16fa83497c4ddad4f90f718258d5d33 329 SUPERFAMILY SSF53807 47 305 1.02E-38 T 23-10-2018 STK_07720 04ce78f92bb7d28d480f787727e6833f 115 SUPERFAMILY SSF46785 8 92 1.23E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_07720 04ce78f92bb7d28d480f787727e6833f 115 Gene3D G3DSA:1.10.10.10 2 113 2.9E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_07720 04ce78f92bb7d28d480f787727e6833f 115 Pfam PF03551 Transcriptional regulator PadR-like family 27 81 7.9E-5 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal STK_22060 a2bfddd9fcc883e28f5b113ccc19fd17 121 Gene3D G3DSA:2.40.50.140 49 120 2.1E-18 T 23-10-2018 STK_22060 a2bfddd9fcc883e28f5b113ccc19fd17 121 Pfam PF01957 NfeD-like C-terminal, partner-binding 11 114 4.9E-18 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain STK_22060 a2bfddd9fcc883e28f5b113ccc19fd17 121 SUPERFAMILY SSF141322 53 115 1.31E-17 T 23-10-2018 STK_22305 89240352fdc57f79f34034b934f321d8 71 Pfam PF07935 ORF D-335-like protein 5 59 9.2E-21 T 23-10-2018 IPR012922 ORF D-335-like STK_19200 0254e2bc090e068d47fe421bdbe5e513 315 Gene3D G3DSA:1.20.120.20 73 204 9.4E-6 T 23-10-2018 STK_19200 0254e2bc090e068d47fe421bdbe5e513 315 SUPERFAMILY SSF58113 46 158 7.98E-6 T 23-10-2018 STK_11200 52b4e2f4821d8fef4e2fc5719d9d7fb7 350 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 317 1.5E-53 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 STK_11200 52b4e2f4821d8fef4e2fc5719d9d7fb7 350 SUPERFAMILY SSF51395 1 317 2.66E-70 T 23-10-2018 STK_11200 52b4e2f4821d8fef4e2fc5719d9d7fb7 350 Gene3D G3DSA:3.20.20.70 4 308 1.4E-94 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_11200 52b4e2f4821d8fef4e2fc5719d9d7fb7 350 PIRSF PIRSF000164 1 319 7.7E-93 T 23-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 STK_11200 52b4e2f4821d8fef4e2fc5719d9d7fb7 350 Pfam PF01180 Dihydroorotate dehydrogenase 4 302 6.2E-36 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 STK_07195 bbf0260d30f4341f2c818782bf9dcdad 163 SUPERFAMILY SSF103473 5 130 4.32E-8 T 23-10-2018 IPR036259 MFS transporter superfamily STK_07195 bbf0260d30f4341f2c818782bf9dcdad 163 Gene3D G3DSA:1.20.1250.20 4 158 4.0E-6 T 23-10-2018 STK_02550 6463b2a9a796edf633ca4dccc2517a15 256 Pfam PF00589 Phage integrase family 59 221 1.0E-14 T 23-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 STK_02550 6463b2a9a796edf633ca4dccc2517a15 256 SUPERFAMILY SSF56349 9 228 3.53E-21 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 STK_25280 5ab9e00ff3c478faaffa7d78e1b583e2 367 SUPERFAMILY SSF103473 6 310 9.68E-5 T 23-10-2018 IPR036259 MFS transporter superfamily STK_20260 22faa7b3224e12d049e00497c610e4c5 322 Pfam PF00756 Putative esterase 103 306 2.8E-13 T 23-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 STK_20260 22faa7b3224e12d049e00497c610e4c5 322 SUPERFAMILY SSF53474 36 301 7.62E-27 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold STK_11670 6fcfaae02820e9ba04fd0fe95fbfa54d 330 Pfam PF05598 Transposase domain (DUF772) 47 111 7.1E-8 T 23-10-2018 IPR008490 Transposase InsH, N-terminal STK_08470 6fcfaae02820e9ba04fd0fe95fbfa54d 330 Pfam PF05598 Transposase domain (DUF772) 47 111 7.1E-8 T 23-10-2018 IPR008490 Transposase InsH, N-terminal STK_19160 6fcfaae02820e9ba04fd0fe95fbfa54d 330 Pfam PF05598 Transposase domain (DUF772) 47 111 7.1E-8 T 23-10-2018 IPR008490 Transposase InsH, N-terminal STK_09070 6fcfaae02820e9ba04fd0fe95fbfa54d 330 Pfam PF05598 Transposase domain (DUF772) 47 111 7.1E-8 T 23-10-2018 IPR008490 Transposase InsH, N-terminal STK_13790 c46df3ae5777613690e93b2613f77f67 131 SUPERFAMILY SSF75169 1 129 2.69E-19 T 23-10-2018 IPR027396 DsrEFH-like STK_13790 c46df3ae5777613690e93b2613f77f67 131 Pfam PF13686 DsrE/DsrF/DrsH-like family 54 127 1.8E-9 T 23-10-2018 IPR032836 DsrE2-like family STK_13790 c46df3ae5777613690e93b2613f77f67 131 Gene3D G3DSA:3.40.1260.10 1 130 1.8E-22 T 23-10-2018 IPR027396 DsrEFH-like STK_01925 e250532b66cb8c605aefb6b58e1aa188 56 Gene3D G3DSA:2.20.28.160 1 56 2.1E-28 T 23-10-2018 STK_05600 4b42818400f3730a19dd5c8309b78217 185 Pfam PF12804 MobA-like NTP transferase domain 5 157 1.6E-31 T 23-10-2018 IPR025877 MobA-like NTP transferase STK_05600 4b42818400f3730a19dd5c8309b78217 185 SUPERFAMILY SSF53448 1 179 6.98E-29 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_05600 4b42818400f3730a19dd5c8309b78217 185 Gene3D G3DSA:3.90.550.10 2 176 8.2E-49 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_19290 b2e1be78f1167674f9d7fbb07eba4fc3 141 Pfam PF04693 Archaeal putative transposase ISC1217 7 92 2.0E-32 T 23-10-2018 IPR006783 Transposase, ISC1217 STK_25200 50d8747070822f5f965d70f168827dcf 154 Pfam PF01917 Archaebacterial flagellin 5 151 8.4E-12 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 STK_02740 f0e795c1d5a3178cc0aab3c452994a21 106 ProSitePatterns PS00709 Ribosomal protein L30e signature 1. 17 41 - T 23-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_02740 f0e795c1d5a3178cc0aab3c452994a21 106 Gene3D G3DSA:3.30.1330.30 3 106 5.8E-35 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like STK_02740 f0e795c1d5a3178cc0aab3c452994a21 106 SUPERFAMILY SSF55315 7 99 5.15E-28 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like STK_02740 f0e795c1d5a3178cc0aab3c452994a21 106 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 8 98 2.1E-19 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 STK_02740 f0e795c1d5a3178cc0aab3c452994a21 106 ProSitePatterns PS00993 Ribosomal protein L30e signature 2. 73 93 - T 23-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_02740 f0e795c1d5a3178cc0aab3c452994a21 106 Hamap MF_00481 50S ribosomal protein L30e [rpl30e]. 5 102 31.292 T 23-10-2018 IPR000231 Ribosomal protein L30e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_06050 23ee8b104520f770f1d3fa78c8692d34 244 Pfam PF07758 Protein of unknown function (DUF1614) 60 237 5.0E-47 T 23-10-2018 IPR011672 Protein of unknown function DUF1614 STK_14820 6831dd64dad91ea50e6900022cbd856e 213 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 2 197 2.0E-23 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 STK_14820 6831dd64dad91ea50e6900022cbd856e 213 Hamap MF_01200_A Orotidine 5'-phosphate decarboxylase [pyrF]. 1 207 36.164 T 23-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 STK_14820 6831dd64dad91ea50e6900022cbd856e 213 SUPERFAMILY SSF51366 2 201 1.45E-39 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 STK_14820 6831dd64dad91ea50e6900022cbd856e 213 Gene3D G3DSA:3.20.20.70 1 213 6.1E-51 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_14820 6831dd64dad91ea50e6900022cbd856e 213 SMART SM00934 1 197 1.3E-23 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 STK_14820 6831dd64dad91ea50e6900022cbd856e 213 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 49 62 - T 23-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 STK_01170 d1c3bb02c6ca361312037b504eb8f03b 550 SUPERFAMILY SSF50998 140 286 2.67E-5 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily STK_17040 7f0c569ad58e533029da63ece279af0c 360 Pfam PF16912 Glucose dehydrogenase C-terminus 147 357 4.0E-27 T 23-10-2018 IPR031640 Glucose dehydrogenase, C-terminal KEGG: 00030+1.1.1.47 STK_17040 7f0c569ad58e533029da63ece279af0c 360 Gene3D G3DSA:3.90.180.10 13 357 8.9E-116 T 23-10-2018 STK_17040 7f0c569ad58e533029da63ece279af0c 360 SUPERFAMILY SSF51735 183 317 2.44E-12 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_17040 7f0c569ad58e533029da63ece279af0c 360 SUPERFAMILY SSF50129 1 197 1.48E-39 T 23-10-2018 IPR011032 GroES-like superfamily STK_17040 7f0c569ad58e533029da63ece279af0c 360 Hamap MF_02127 Glucose 1-dehydrogenase [gdh]. 1 360 62.37 T 23-10-2018 IPR026583 Glucose 1-dehydrogenase GO:0005536|GO:0008270|GO:0047936 KEGG: 00030+1.1.1.47 STK_17040 7f0c569ad58e533029da63ece279af0c 360 Gene3D G3DSA:3.40.50.720 149 332 8.9E-116 T 23-10-2018 STK_17040 7f0c569ad58e533029da63ece279af0c 360 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 141 6.4E-23 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 STK_24640 07d9e9eb27b81e746b7203c8a83e561e 303 Gene3D G3DSA:1.20.58.1130 5 193 3.1E-34 T 23-10-2018 STK_24640 07d9e9eb27b81e746b7203c8a83e561e 303 Gene3D G3DSA:1.20.1420.30 31 293 3.1E-34 T 23-10-2018 STK_24640 07d9e9eb27b81e746b7203c8a83e561e 303 Pfam PF01699 Sodium/calcium exchanger protein 162 300 3.1E-13 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 STK_24640 07d9e9eb27b81e746b7203c8a83e561e 303 Pfam PF01699 Sodium/calcium exchanger protein 3 142 1.1E-14 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 STK_04880 b23a9309c0b45d9326dc571298d055ed 301 SUPERFAMILY SSF56059 101 299 2.02E-47 T 23-10-2018 STK_04880 b23a9309c0b45d9326dc571298d055ed 301 Gene3D G3DSA:3.30.1490.20 127 190 1.8E-5 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 STK_04880 b23a9309c0b45d9326dc571298d055ed 301 Pfam PF08443 RimK-like ATP-grasp domain 109 295 4.9E-30 T 23-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 STK_04880 b23a9309c0b45d9326dc571298d055ed 301 Gene3D G3DSA:3.30.470.80 191 301 1.5E-34 T 23-10-2018 STK_04880 b23a9309c0b45d9326dc571298d055ed 301 Gene3D G3DSA:3.40.50.20 10 125 1.0E-9 T 23-10-2018 STK_04880 b23a9309c0b45d9326dc571298d055ed 301 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 18 294 5.3E-60 T 23-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 STK_08620 a8f88c99baf0c54c05231f398ffecc8e 216 Gene3D G3DSA:3.40.50.880 2 211 5.3E-50 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_08620 a8f88c99baf0c54c05231f398ffecc8e 216 Pfam PF00117 Glutamine amidotransferase class-I 33 171 9.0E-17 T 23-10-2018 IPR017926 Glutamine amidotransferase STK_08620 a8f88c99baf0c54c05231f398ffecc8e 216 SUPERFAMILY SSF52317 19 214 2.29E-44 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_20800 22a5680b56bd4d0e1620b585235ebf0d 172 Pfam PF06557 Protein of unknown function (DUF1122) 7 167 8.1E-65 T 23-10-2018 IPR008304 Uncharacterised conserved protein UCP017998 STK_20800 22a5680b56bd4d0e1620b585235ebf0d 172 PIRSF PIRSF017998 1 172 4.6E-75 T 23-10-2018 IPR008304 Uncharacterised conserved protein UCP017998 STK_20800 22a5680b56bd4d0e1620b585235ebf0d 172 Gene3D G3DSA:3.40.630.30 2 142 1.2E-43 T 23-10-2018 STK_20800 22a5680b56bd4d0e1620b585235ebf0d 172 SUPERFAMILY SSF55729 5 171 1.91E-64 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase STK_00400 c17ac6898c21a40e8cd7d9f0cbd1b4ff 152 Gene3D G3DSA:3.30.300.130 1 90 3.4E-13 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily STK_00400 c17ac6898c21a40e8cd7d9f0cbd1b4ff 152 Pfam PF01883 Iron-sulfur cluster assembly protein 3 62 3.6E-8 T 23-10-2018 IPR002744 MIP18 family-like STK_00400 c17ac6898c21a40e8cd7d9f0cbd1b4ff 152 SUPERFAMILY SSF117916 3 86 6.87E-13 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily STK_11640 f57a269dd726ce18e98820c9fba768fa 532 Pfam PF13360 PQQ-like domain 228 398 2.4E-12 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat STK_11640 f57a269dd726ce18e98820c9fba768fa 532 Gene3D G3DSA:2.40.128.630 410 524 9.2E-10 T 23-10-2018 STK_11640 f57a269dd726ce18e98820c9fba768fa 532 SMART SM00564 298 337 530.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat STK_11640 f57a269dd726ce18e98820c9fba768fa 532 SMART SM00564 188 245 47.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat STK_11640 f57a269dd726ce18e98820c9fba768fa 532 SMART SM00564 145 179 7.8 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat STK_11640 f57a269dd726ce18e98820c9fba768fa 532 SMART SM00564 253 285 69.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat STK_11640 f57a269dd726ce18e98820c9fba768fa 532 SMART SM00564 354 396 38.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat STK_11640 f57a269dd726ce18e98820c9fba768fa 532 SMART SM00564 411 443 9.7 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat STK_11640 f57a269dd726ce18e98820c9fba768fa 532 SMART SM00564 460 491 790.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat STK_11640 f57a269dd726ce18e98820c9fba768fa 532 Gene3D G3DSA:2.130.10.10 137 370 5.1E-21 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 STK_11640 f57a269dd726ce18e98820c9fba768fa 532 SUPERFAMILY SSF50998 159 511 1.05E-27 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily STK_16850 c2b27aaaf6bf323d6c74abcc8ce2ab12 503 Pfam PF02538 Hydantoinase B/oxoprolinase 2 500 1.8E-177 T 23-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 STK_06135 6d43d18a56f0b2eaa799eff3f4052a6e 77 Gene3D G3DSA:3.30.110.40 3 77 3.3E-14 T 23-10-2018 IPR036868 TusA-like domain superfamily STK_06135 6d43d18a56f0b2eaa799eff3f4052a6e 77 Pfam PF01206 Sulfurtransferase TusA 8 76 7.2E-14 T 23-10-2018 IPR001455 TusA-like domain STK_06135 6d43d18a56f0b2eaa799eff3f4052a6e 77 SUPERFAMILY SSF64307 2 77 7.98E-15 T 23-10-2018 IPR036868 TusA-like domain superfamily STK_12230 cd9ac62dba327d4854f0706d1e720871 326 Gene3D G3DSA:3.50.50.60 103 324 1.5E-18 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_12230 cd9ac62dba327d4854f0706d1e720871 326 SUPERFAMILY SSF51905 2 254 2.15E-8 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_12230 cd9ac62dba327d4854f0706d1e720871 326 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 35 1.3E-4 T 23-10-2018 STK_05790 29ae4641a2d4822e3800afd0766edbed 258 Gene3D G3DSA:3.40.50.300 2 233 3.8E-70 T 23-10-2018 STK_05790 29ae4641a2d4822e3800afd0766edbed 258 Pfam PF06745 KaiC 5 229 3.8E-59 T 23-10-2018 IPR014774 KaiC-like domain STK_05790 29ae4641a2d4822e3800afd0766edbed 258 TIGRFAM TIGR03881 KaiC_arch_4: KaiC domain protein, PAE1156 family 3 230 8.6E-122 T 23-10-2018 IPR022443 KaiC-related STK_05790 29ae4641a2d4822e3800afd0766edbed 258 SUPERFAMILY SSF52540 1 233 2.67E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_05790 29ae4641a2d4822e3800afd0766edbed 258 PRINTS PR01874 DNA repair protein radA signature 13 41 4.0E-7 T 23-10-2018 STK_05790 29ae4641a2d4822e3800afd0766edbed 258 PRINTS PR01874 DNA repair protein radA signature 55 72 4.0E-7 T 23-10-2018 STK_16840 a7b669066f38ff60073c16171a8ab353 184 SUPERFAMILY SSF52141 26 179 1.44E-37 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 STK_16840 a7b669066f38ff60073c16171a8ab353 184 Gene3D G3DSA:3.40.50.10630 14 183 6.2E-33 T 23-10-2018 STK_00080 6d22e27abf4e93e9800e6eac2f0b0a30 242 Pfam PF03787 RAMP superfamily 22 213 7.1E-21 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein STK_00080 6d22e27abf4e93e9800e6eac2f0b0a30 242 TIGRFAM TIGR02581 cas_cyan_RAMP: CRISPR-associated RAMP protein, SSO1426 family 14 220 5.0E-87 T 23-10-2018 IPR013411 CRISPR-associated RAMP TM1809 STK_16950 35b26fd6db94053ec4d11e0fb287d888 137 Pfam PF06146 Phosphate-starvation-inducible E 60 127 3.5E-8 T 23-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like STK_24790 7a99cee4d31475d8b719a37d76f48863 290 Pfam PF00701 Dihydrodipicolinate synthetase family 3 276 3.9E-43 T 23-10-2018 IPR002220 DapA-like GO:0016829 STK_24790 7a99cee4d31475d8b719a37d76f48863 290 SMART SM01130 1 282 3.7E-54 T 23-10-2018 IPR002220 DapA-like GO:0016829 STK_24790 7a99cee4d31475d8b719a37d76f48863 290 Gene3D G3DSA:3.20.20.70 1 290 2.0E-88 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_24790 7a99cee4d31475d8b719a37d76f48863 290 SUPERFAMILY SSF51569 3 281 1.26E-63 T 23-10-2018 STK_24790 7a99cee4d31475d8b719a37d76f48863 290 PIRSF PIRSF001365 1 289 1.8E-52 T 23-10-2018 IPR002220 DapA-like GO:0016829 STK_24790 7a99cee4d31475d8b719a37d76f48863 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 33 54 6.7E-10 T 23-10-2018 IPR002220 DapA-like GO:0016829 STK_24790 7a99cee4d31475d8b719a37d76f48863 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 66 84 6.7E-10 T 23-10-2018 IPR002220 DapA-like GO:0016829 STK_24790 7a99cee4d31475d8b719a37d76f48863 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 124 141 6.7E-10 T 23-10-2018 IPR002220 DapA-like GO:0016829 STK_15060 a102032923f2a029a0f70b50fbd668f8 195 Pfam PF01997 Translin family 22 182 6.7E-6 T 23-10-2018 IPR002848 Translin family GO:0043565 Reactome: R-HSA-426486 STK_15060 a102032923f2a029a0f70b50fbd668f8 195 SUPERFAMILY SSF74784 6 187 9.42E-23 T 23-10-2018 IPR036081 Translin superfamily GO:0043565 Reactome: R-HSA-426486 STK_15060 a102032923f2a029a0f70b50fbd668f8 195 Gene3D G3DSA:1.20.58.2140 6 195 7.2E-52 T 23-10-2018 STK_15770 85b9eac1441495e106d8cc2ab09ccb6a 237 SUPERFAMILY SSF52540 3 217 5.64E-62 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_15770 85b9eac1441495e106d8cc2ab09ccb6a 237 Pfam PF00005 ABC transporter 19 159 6.6E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_15770 85b9eac1441495e106d8cc2ab09ccb6a 237 Gene3D G3DSA:3.40.50.300 1 235 1.7E-65 T 23-10-2018 STK_15770 85b9eac1441495e106d8cc2ab09ccb6a 237 SMART SM00382 28 205 3.8E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_23290 d589605a5fecd09a9be0f17a71717998 402 Gene3D G3DSA:3.40.1190.20 1 272 1.0E-86 T 23-10-2018 IPR029056 Ribokinase-like STK_23290 d589605a5fecd09a9be0f17a71717998 402 Pfam PF08543 Phosphomethylpyrimidine kinase 13 253 2.4E-80 T 23-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 STK_23290 d589605a5fecd09a9be0f17a71717998 402 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 254 1.3E-93 T 23-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 STK_23290 d589605a5fecd09a9be0f17a71717998 402 SUPERFAMILY SSF53613 4 257 9.35E-74 T 23-10-2018 IPR029056 Ribokinase-like STK_23290 d589605a5fecd09a9be0f17a71717998 402 SUPERFAMILY SSF53639 262 400 3.61E-14 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily STK_05450 89813ba1442d261d5de0ec0ab670d7c3 505 TIGRFAM TIGR00284 TIGR00284: dihydropteroate synthase-related protein 1 487 1.3E-147 T 23-10-2018 IPR005236 Dihydropteroate synthase-related protein synthase-related protein STK_05450 89813ba1442d261d5de0ec0ab670d7c3 505 SUPERFAMILY SSF51717 186 363 5.81E-11 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 STK_08840 2cba9f0f5c5f75d2e74e2ee4dab63a69 134 SUPERFAMILY SSF53756 2 130 1.36E-28 T 23-10-2018 STK_08840 2cba9f0f5c5f75d2e74e2ee4dab63a69 134 Pfam PF00534 Glycosyl transferases group 1 2 132 1.7E-20 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 STK_08840 2cba9f0f5c5f75d2e74e2ee4dab63a69 134 Gene3D G3DSA:3.40.50.2000 1 134 1.3E-26 T 23-10-2018 STK_18660 9ba4c16eea88bd01d0e66f31c5fab035 315 SUPERFAMILY SSF51735 1 264 1.45E-29 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_18660 9ba4c16eea88bd01d0e66f31c5fab035 315 Gene3D G3DSA:3.40.50.720 1 282 3.5E-28 T 23-10-2018 STK_18660 9ba4c16eea88bd01d0e66f31c5fab035 315 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 176 2.1E-15 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 STK_18930 d0f2b125c062afef36d4523aee01ff4e 160 SUPERFAMILY SSF56784 16 156 1.24E-8 T 23-10-2018 IPR036412 HAD-like superfamily STK_18930 d0f2b125c062afef36d4523aee01ff4e 160 Gene3D G3DSA:3.40.50.1000 27 159 7.7E-6 T 23-10-2018 IPR023214 HAD superfamily STK_07390 b2ddb2b5e2304babd320a40c8ebd521f 682 SMART SM01008 11 117 6.9E-26 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead STK_07390 b2ddb2b5e2304babd320a40c8ebd521f 682 SUPERFAMILY SSF54665 4 121 6.15E-26 T 23-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily STK_07390 b2ddb2b5e2304babd320a40c8ebd521f 682 SUPERFAMILY SSF56003 109 679 2.62E-127 T 23-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 STK_07390 b2ddb2b5e2304babd320a40c8ebd521f 682 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 139 621 4.3E-108 T 23-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 STK_07390 b2ddb2b5e2304babd320a40c8ebd521f 682 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 11 116 6.7E-11 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead STK_07390 b2ddb2b5e2304babd320a40c8ebd521f 682 Gene3D G3DSA:3.30.365.10 1 675 2.1E-140 T 23-10-2018 STK_00680 7ac796d236f44459827e2aaeee0cc496 165 SUPERFAMILY SSF54637 6 157 1.49E-44 T 23-10-2018 IPR029069 HotDog domain superfamily STK_00680 7ac796d236f44459827e2aaeee0cc496 165 Gene3D G3DSA:3.10.129.10 3 156 2.0E-46 T 23-10-2018 STK_00680 7ac796d236f44459827e2aaeee0cc496 165 Pfam PF01575 MaoC like domain 15 121 1.0E-16 T 23-10-2018 IPR002539 MaoC-like dehydratase domain STK_09470 66deac97de985a8576228b99bbac3d01 306 Pfam PF01170 Putative RNA methylase family UPF0020 140 277 1.3E-21 T 23-10-2018 IPR000241 Putative RNA methylase domain STK_09470 66deac97de985a8576228b99bbac3d01 306 Gene3D G3DSA:3.40.50.150 136 306 7.3E-29 T 23-10-2018 STK_09470 66deac97de985a8576228b99bbac3d01 306 SUPERFAMILY SSF53335 131 252 1.2E-21 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_22910 700bed18cdf6112f6dd607b0dc9adcc4 338 Gene3D G3DSA:3.90.550.10 22 232 6.7E-24 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_22910 700bed18cdf6112f6dd607b0dc9adcc4 338 SUPERFAMILY SSF53448 39 303 6.57E-35 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_22910 700bed18cdf6112f6dd607b0dc9adcc4 338 Pfam PF00535 Glycosyl transferase family 2 39 197 1.8E-20 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 STK_09210 9f2f8c0693e3b6f4939b1b1e3eb4d829 184 Pfam PF09623 CRISPR-associated protein NE0113 (Cas_NE0113) 35 118 2.7E-5 T 23-10-2018 IPR019092 CRISPR-assoc protein, NE0113/Csx13 STK_06820 9abcc4d1cae7ebde793c2692d1e90077 187 SUPERFAMILY SSF53056 4 121 3.27E-15 T 23-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 STK_06820 9abcc4d1cae7ebde793c2692d1e90077 187 Gene3D G3DSA:3.40.1050.10 2 129 3.6E-9 T 23-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 STK_04690 520bdd10a61762c5986c01f84ca3f98f 183 Gene3D G3DSA:1.20.58.1030 68 177 5.5E-8 T 23-10-2018 STK_04690 520bdd10a61762c5986c01f84ca3f98f 183 Pfam PF05916 GINS complex protein 47 160 3.3E-12 T 23-10-2018 IPR021151 GINS subunit, domain A Reactome: R-HSA-176974 STK_12995 4e3c29033f5a8a5654a37d032b42aba2 61 Gene3D G3DSA:2.30.30.610 6 61 1.3E-33 T 23-10-2018 IPR038647 Cren7 superfamily STK_12995 4e3c29033f5a8a5654a37d032b42aba2 61 Pfam PF11520 Chromatin protein Cren7 5 60 2.0E-32 T 23-10-2018 IPR020906 Double-stranded DNA-binding Cren7 GO:0003690|GO:0005737 STK_12995 4e3c29033f5a8a5654a37d032b42aba2 61 Hamap MF_01387 Chromatin protein Cren7 [creN7]. 1 60 19.902 T 23-10-2018 IPR020906 Double-stranded DNA-binding Cren7 GO:0003690|GO:0005737 STK_02850 43e44f34bb9612cfd7b3189045b07b31 213 Gene3D G3DSA:3.40.430.10 1 212 4.5E-51 T 23-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 STK_02850 43e44f34bb9612cfd7b3189045b07b31 213 Pfam PF01872 RibD C-terminal domain 3 207 5.6E-40 T 23-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 STK_02850 43e44f34bb9612cfd7b3189045b07b31 213 TIGRFAM TIGR01508 rib_reduct_arch: diaminohydroxyphosphoribosylaminopyrimidine reductase 3 210 2.1E-61 T 23-10-2018 IPR006401 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal GO:0016491|GO:0055114 KEGG: 00740+1.1.1.302|MetaCyc: PWY-6167|MetaCyc: PWY-6168 STK_02850 43e44f34bb9612cfd7b3189045b07b31 213 SUPERFAMILY SSF53597 1 209 1.6E-48 T 23-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 STK_07090 c8ccfdaa8b6d518d327c9b4af1031272 105 TIGRFAM TIGR03698 clan_AA_DTGF: clan AA aspartic protease, AF_0612 family 14 99 4.5E-18 T 23-10-2018 IPR022274 Peptidase aspartic, AF0612 STK_01700 efdff516e8c9f8f5efae78a265ddaa16 147 SUPERFAMILY SSF88659 4 54 2.01E-5 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like STK_01700 efdff516e8c9f8f5efae78a265ddaa16 147 Pfam PF13384 Homeodomain-like domain 56 87 1.0E-5 T 23-10-2018 STK_01700 efdff516e8c9f8f5efae78a265ddaa16 147 SUPERFAMILY SSF46689 44 92 5.68E-7 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 STK_01700 efdff516e8c9f8f5efae78a265ddaa16 147 Pfam PF13936 Helix-turn-helix domain 94 134 2.5E-9 T 23-10-2018 IPR025246 Transposase IS30-like HTH domain STK_01700 efdff516e8c9f8f5efae78a265ddaa16 147 Gene3D G3DSA:1.10.10.60 95 139 7.0E-17 T 23-10-2018 STK_01700 efdff516e8c9f8f5efae78a265ddaa16 147 Gene3D G3DSA:1.10.10.60 2 44 5.6E-10 T 23-10-2018 STK_01700 efdff516e8c9f8f5efae78a265ddaa16 147 Gene3D G3DSA:1.10.10.60 45 94 1.0E-9 T 23-10-2018 STK_10270 cece942468f4541095d5a521afde3e25 159 SMART SM00988 9 74 7.1E-8 T 23-10-2018 IPR004029 UreE urease accessory, N-terminal STK_10270 cece942468f4541095d5a521afde3e25 159 SUPERFAMILY SSF69287 26 75 3.4E-6 T 23-10-2018 IPR036118 UreE urease accessory, N-terminal domain superfamily STK_10270 cece942468f4541095d5a521afde3e25 159 Pfam PF02814 UreE urease accessory protein, N-terminal domain 29 74 2.1E-6 T 23-10-2018 IPR004029 UreE urease accessory, N-terminal STK_14515 14d92b7fe328fe30827a5e736fe95fef 217 Gene3D G3DSA:3.50.50.60 17 210 3.0E-7 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_18100 a25975b7b0a245360f27c765abff0054 431 SUPERFAMILY SSF103378 2 426 1.31E-109 T 23-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 STK_18100 a25975b7b0a245360f27c765abff0054 431 Gene3D G3DSA:1.10.4100.10 11 410 1.1E-92 T 23-10-2018 STK_18100 a25975b7b0a245360f27c765abff0054 431 Pfam PF03972 MmgE/PrpD family 6 401 5.2E-100 T 23-10-2018 IPR005656 MmgE/PrpD GO:0016829 STK_18100 a25975b7b0a245360f27c765abff0054 431 Gene3D G3DSA:3.30.1330.120 256 384 1.1E-92 T 23-10-2018 STK_17820 7b9a368562a30bf5787d9d77a2b44ce1 162 Gene3D G3DSA:1.10.150.120 83 162 5.1E-35 T 23-10-2018 STK_17820 7b9a368562a30bf5787d9d77a2b44ce1 162 SUPERFAMILY SSF54292 9 86 6.16E-26 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 STK_17820 7b9a368562a30bf5787d9d77a2b44ce1 162 SUPERFAMILY SSF47741 92 161 3.66E-34 T 23-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily STK_17820 7b9a368562a30bf5787d9d77a2b44ce1 162 Pfam PF01799 [2Fe-2S] binding domain 81 153 4.8E-32 T 23-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 STK_17820 7b9a368562a30bf5787d9d77a2b44ce1 162 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 14 67 3.5E-5 T 23-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 STK_17820 7b9a368562a30bf5787d9d77a2b44ce1 162 Gene3D G3DSA:3.10.20.30 2 82 1.1E-32 T 23-10-2018 IPR012675 Beta-grasp domain superfamily STK_12000 ba8982ece0937c1fa1a1d9a56570ff6c 479 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 26 468 9.9E-192 T 23-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 STK_12000 ba8982ece0937c1fa1a1d9a56570ff6c 479 Pfam PF01458 Uncharacterized protein family (UPF0051) 222 448 3.6E-63 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 STK_12000 ba8982ece0937c1fa1a1d9a56570ff6c 479 SUPERFAMILY SSF101960 42 473 5.1E-125 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily STK_06080 41af33e2a539686e096fc31ddb108545 242 SMART SM00382 29 207 1.6E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_06080 41af33e2a539686e096fc31ddb108545 242 Pfam PF00005 ABC transporter 20 158 1.2E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_06080 41af33e2a539686e096fc31ddb108545 242 SUPERFAMILY SSF52540 3 222 1.02E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_06080 41af33e2a539686e096fc31ddb108545 242 Gene3D G3DSA:3.40.50.300 1 240 2.1E-66 T 23-10-2018 STK_19900 395e5c2cbeacc467335deff94cc50927 804 Gene3D G3DSA:3.30.70.2220 264 474 9.4E-7 T 23-10-2018 IPR038242 Cmr2, N-terminal domain superfamily STK_04550 2bbc7212526a5d1c6c820bdcbea6e5e3 201 SUPERFAMILY SSF53335 10 176 2.43E-25 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_04550 2bbc7212526a5d1c6c820bdcbea6e5e3 201 Gene3D G3DSA:3.40.50.150 18 200 4.8E-32 T 23-10-2018 STK_04550 2bbc7212526a5d1c6c820bdcbea6e5e3 201 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 21 193 2.4E-27 T 23-10-2018 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 STK_04550 2bbc7212526a5d1c6c820bdcbea6e5e3 201 Pfam PF05175 Methyltransferase small domain 27 115 5.3E-10 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 STK_04550 2bbc7212526a5d1c6c820bdcbea6e5e3 201 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 109 115 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 STK_01790 4af36bdabc6d9e4e6dd4e27b748f20e5 287 Gene3D G3DSA:3.40.225.10 106 287 2.3E-47 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily STK_01790 4af36bdabc6d9e4e6dd4e27b748f20e5 287 SUPERFAMILY SSF53639 109 283 3.3E-51 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily STK_01790 4af36bdabc6d9e4e6dd4e27b748f20e5 287 Pfam PF10120 Thiamine-phosphate synthase 118 275 6.0E-51 T 23-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 STK_01790 4af36bdabc6d9e4e6dd4e27b748f20e5 287 SUPERFAMILY SSF47413 2 45 8.44E-5 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 STK_02540 9d7edf8c25daf12138fc0ff5972ec2de 168 Pfam PF06939 Protein of unknown function (DUF1286) 1 112 1.0E-44 T 23-10-2018 IPR009705 Sulfolobus virus STSV1, Orf8 STK_17140 437bbe9187ec323cab4bb19d935ced8b 142 Gene3D G3DSA:1.20.120.330 7 134 2.0E-21 T 23-10-2018 STK_17140 437bbe9187ec323cab4bb19d935ced8b 142 Pfam PF05168 HEPN domain 10 134 3.7E-22 T 23-10-2018 IPR007842 HEPN domain STK_17140 437bbe9187ec323cab4bb19d935ced8b 142 SMART SM00748 11 128 7.9E-4 T 23-10-2018 IPR007842 HEPN domain STK_17140 437bbe9187ec323cab4bb19d935ced8b 142 SUPERFAMILY SSF81593 11 136 7.06E-17 T 23-10-2018 STK_05810 64d6b46a083f811226c3c0a97beedd3b 196 Gene3D G3DSA:3.30.2170.10 4 196 7.4E-37 T 23-10-2018 STK_05810 64d6b46a083f811226c3c0a97beedd3b 196 Pfam PF04493 Endonuclease V 18 177 2.3E-31 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 STK_05810 64d6b46a083f811226c3c0a97beedd3b 196 Hamap MF_00801 Endonuclease V [nfi]. 5 196 25.693 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 STK_20120 fad945785c7010b11bf3621078c48d69 137 SUPERFAMILY SSF88723 2 126 3.92E-17 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_20120 fad945785c7010b11bf3621078c48d69 137 Gene3D G3DSA:3.40.50.1010 1 130 2.4E-25 T 23-10-2018 STK_20120 fad945785c7010b11bf3621078c48d69 137 Pfam PF01850 PIN domain 2 123 5.1E-11 T 23-10-2018 IPR002716 PIN domain STK_23330 0750d373aa5879bd2bdc8efffb2316a4 378 SUPERFAMILY SSF53383 25 377 1.39E-76 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase STK_23330 0750d373aa5879bd2bdc8efffb2316a4 378 Gene3D G3DSA:3.40.640.10 60 275 2.3E-89 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 STK_23330 0750d373aa5879bd2bdc8efffb2316a4 378 Pfam PF00155 Aminotransferase class I and II 26 369 3.2E-25 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 STK_23330 0750d373aa5879bd2bdc8efffb2316a4 378 Gene3D G3DSA:3.90.1150.10 21 374 2.3E-89 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 STK_13005 28fb9c3834bd21e1245ddee38b58d914 91 Gene3D G3DSA:1.20.120.970 1 91 9.4E-40 T 23-10-2018 STK_07160 ab1b631bfa2b7e37106b72bf6916d780 156 Pfam PF04693 Archaeal putative transposase ISC1217 4 128 9.8E-60 T 23-10-2018 IPR006783 Transposase, ISC1217 STK_11390 7644fa88e1f827590c0a9192043e03ef 244 Gene3D G3DSA:1.10.10.10 48 96 1.7E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_11390 7644fa88e1f827590c0a9192043e03ef 244 SUPERFAMILY SSF46689 49 131 9.41E-10 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 STK_11390 7644fa88e1f827590c0a9192043e03ef 244 Pfam PF13384 Homeodomain-like domain 52 90 7.7E-8 T 23-10-2018 STK_06700 0792eb090d6e85f01443a3398d0ab82f 325 Gene3D G3DSA:3.60.21.10 79 320 1.7E-22 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like STK_06700 0792eb090d6e85f01443a3398d0ab82f 325 SUPERFAMILY SSF56300 17 322 5.01E-71 T 23-10-2018 STK_06700 0792eb090d6e85f01443a3398d0ab82f 325 Pfam PF00149 Calcineurin-like phosphoesterase 18 281 4.2E-4 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 STK_00160 ac8b7e6cf5d78292fa6e2b22d7e649cf 169 Pfam PF05942 Archaeal PaREP1/PaREP8 family 18 137 2.0E-25 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_06650 606ef501433d1f505bb7f740ceba6cda 418 SUPERFAMILY SSF111283 3 416 4.71E-63 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 STK_06650 606ef501433d1f505bb7f740ceba6cda 418 Pfam PF01523 Putative modulator of DNA gyrase 23 283 1.2E-27 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 STK_22050 454685dc823d36c0d23e39977f85b85d 270 Gene3D G3DSA:3.10.490.10 130 263 1.3E-20 T 23-10-2018 STK_22050 454685dc823d36c0d23e39977f85b85d 270 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 151 247 5.8E-8 T 23-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like STK_22050 454685dc823d36c0d23e39977f85b85d 270 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 4 122 5.6E-23 T 23-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like STK_22050 454685dc823d36c0d23e39977f85b85d 270 Gene3D G3DSA:3.10.490.10 3 129 6.1E-32 T 23-10-2018 STK_22050 454685dc823d36c0d23e39977f85b85d 270 SUPERFAMILY SSF110857 131 260 1.23E-19 T 23-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily STK_22050 454685dc823d36c0d23e39977f85b85d 270 SUPERFAMILY SSF110857 1 128 1.11E-30 T 23-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily STK_06060 f25777adcac79e378c3e79a5ac504ac2 157 Pfam PF12804 MobA-like NTP transferase domain 1 98 2.5E-8 T 23-10-2018 IPR025877 MobA-like NTP transferase STK_06060 f25777adcac79e378c3e79a5ac504ac2 157 SUPERFAMILY SSF53448 1 151 6.76E-21 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_06060 f25777adcac79e378c3e79a5ac504ac2 157 Gene3D G3DSA:3.90.550.10 1 153 1.4E-21 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_10354 1769ebe14acdbd9a8b0e67c06e448f33 78 SUPERFAMILY SSF90123 2 65 9.94E-5 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 STK_17780 7935598dd5e7b641ea29d6e22aab21ff 281 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 243 279 1.5E-6 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_24410 57583ed5d24e06b5be15edd6adf46095 338 SUPERFAMILY SSF55909 8 338 6.6E-79 T 23-10-2018 STK_24410 57583ed5d24e06b5be15edd6adf46095 338 Pfam PF02274 Amidinotransferase 25 337 8.9E-56 T 23-10-2018 STK_18500 c28e1a27355de0bad60fe468ef66d7c3 168 Pfam PF06939 Protein of unknown function (DUF1286) 2 112 4.0E-44 T 23-10-2018 IPR009705 Sulfolobus virus STSV1, Orf8 STK_13820 3dcd66b35cb29adb28d251d61f6c43fc 222 Gene3D G3DSA:1.10.510.10 92 199 3.9E-9 T 23-10-2018 STK_13820 3dcd66b35cb29adb28d251d61f6c43fc 222 SUPERFAMILY SSF56112 16 157 6.78E-13 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily STK_05670 0ea20104404e57fac2dd3555fe0800ee 250 Gene3D G3DSA:3.40.50.150 10 250 2.9E-49 T 23-10-2018 STK_05670 0ea20104404e57fac2dd3555fe0800ee 250 Pfam PF02475 Met-10+ like-protein 11 207 1.8E-44 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 STK_05670 0ea20104404e57fac2dd3555fe0800ee 250 SUPERFAMILY SSF53335 6 249 1.2E-50 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_04570 c8b99365c3d41026a1dbc0fbaca00432 222 Gene3D G3DSA:2.40.50.140 12 79 1.5E-16 T 23-10-2018 STK_04570 c8b99365c3d41026a1dbc0fbaca00432 222 Pfam PF04919 Protein of unknown function (DUF655) 11 186 2.0E-60 T 23-10-2018 IPR007003 Protein of unknown function DUF655 STK_04570 c8b99365c3d41026a1dbc0fbaca00432 222 SUPERFAMILY SSF160975 12 186 7.45E-70 T 23-10-2018 STK_04570 c8b99365c3d41026a1dbc0fbaca00432 222 Gene3D G3DSA:1.10.150.280 81 178 3.1E-33 T 23-10-2018 STK_02980 ffd2b75919878a66fb8908d681c53659 174 Gene3D G3DSA:2.30.130.10 106 172 9.5E-6 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 STK_24370 2984e35d9f24d471eb82e4625fe586f8 301 SMART SM00382 26 203 1.0E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_24370 2984e35d9f24d471eb82e4625fe586f8 301 Gene3D G3DSA:3.40.50.300 1 227 4.5E-59 T 23-10-2018 STK_24370 2984e35d9f24d471eb82e4625fe586f8 301 SUPERFAMILY SSF52540 2 218 2.07E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_24370 2984e35d9f24d471eb82e4625fe586f8 301 Pfam PF00005 ABC transporter 17 154 6.5E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_03115 69bd66703688902337e14fc19e9845dc 83 SUPERFAMILY SSF54909 3 76 7.11E-19 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel STK_03115 69bd66703688902337e14fc19e9845dc 83 Pfam PF01037 Lrp/AsnC ligand binding domain 6 76 4.6E-17 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain STK_03115 69bd66703688902337e14fc19e9845dc 83 Gene3D G3DSA:3.30.70.920 1 74 1.7E-27 T 23-10-2018 STK_00050 be331c3096c3a2634ded19560ddf6a07 180 Gene3D G3DSA:3.30.70.1900 31 178 6.7E-11 T 23-10-2018 STK_00050 be331c3096c3a2634ded19560ddf6a07 180 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 58 171 1.4E-5 T 23-10-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal STK_25340 895a9be5c6942add04d18b04f83d021a 683 Gene3D G3DSA:3.10.105.10 329 567 6.5E-32 T 23-10-2018 STK_25340 895a9be5c6942add04d18b04f83d021a 683 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 119 498 6.0E-40 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain STK_25340 895a9be5c6942add04d18b04f83d021a 683 SUPERFAMILY SSF53850 42 588 4.21E-61 T 23-10-2018 STK_25340 895a9be5c6942add04d18b04f83d021a 683 Gene3D G3DSA:3.40.190.10 35 312 9.0E-23 T 23-10-2018 STK_11070 d4755bc9b79cf3dc4161328ff26bd9bf 621 Pfam PF00723 Glycosyl hydrolases family 15 240 280 3.4E-5 T 23-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 STK_11070 d4755bc9b79cf3dc4161328ff26bd9bf 621 SUPERFAMILY SSF48208 195 590 2.93E-71 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 STK_11070 d4755bc9b79cf3dc4161328ff26bd9bf 621 Gene3D G3DSA:1.50.10.10 229 596 3.4E-51 T 23-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 STK_15460 c04a476b010964f5a4a04322b6a1b21c 159 Gene3D G3DSA:3.40.50.1240 3 159 2.3E-34 T 23-10-2018 IPR029033 Histidine phosphatase superfamily STK_15460 c04a476b010964f5a4a04322b6a1b21c 159 SUPERFAMILY SSF53254 1 143 1.96E-27 T 23-10-2018 IPR029033 Histidine phosphatase superfamily STK_15460 c04a476b010964f5a4a04322b6a1b21c 159 SMART SM00855 3 117 2.7E-5 T 23-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 STK_15460 c04a476b010964f5a4a04322b6a1b21c 159 TIGRFAM TIGR00249 sixA: phosphohistidine phosphatase SixA 4 145 2.2E-27 T 23-10-2018 IPR004449 Phosphohistidine phosphatase SixA GO:0005737|GO:0006464|GO:0101006 STK_15460 c04a476b010964f5a4a04322b6a1b21c 159 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 83 4.1E-13 T 23-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 STK_15460 c04a476b010964f5a4a04322b6a1b21c 159 PIRSF PIRSF000709 3 103 4.8E-5 T 23-10-2018 STK_08820 68b2c067377dbf02079364c938d662d7 410 Pfam PF04143 Sulphur transport 35 402 5.6E-66 T 23-10-2018 IPR007272 Sulphur transport domain STK_05010 1221c8228effbe9fdd5337c7bd859296 453 SUPERFAMILY SSF53300 290 428 3.5E-17 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily STK_05010 1221c8228effbe9fdd5337c7bd859296 453 Pfam PF00092 von Willebrand factor type A domain 291 425 8.5E-7 T 23-10-2018 IPR002035 von Willebrand factor, type A STK_05010 1221c8228effbe9fdd5337c7bd859296 453 Gene3D G3DSA:3.40.50.410 292 451 3.2E-13 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily STK_05010 1221c8228effbe9fdd5337c7bd859296 453 SMART SM00327 288 452 4.2E-5 T 23-10-2018 IPR002035 von Willebrand factor, type A STK_01590 7a6f82d4ddebcfecb404af494bf34a40 172 Gene3D G3DSA:1.10.10.10 11 98 4.0E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_01590 7a6f82d4ddebcfecb404af494bf34a40 172 SUPERFAMILY SSF46785 15 91 1.12E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_01590 7a6f82d4ddebcfecb404af494bf34a40 172 Pfam PF13412 Winged helix-turn-helix DNA-binding 15 59 1.4E-6 T 23-10-2018 STK_24870 b5b8be000e7bf0585324897d7e530843 284 Pfam PF07849 Protein of unknown function (DUF1641) 232 269 7.6E-12 T 23-10-2018 IPR012440 Protein of unknown function DUF1641 STK_21320 55c01fddc3518039bcdc04c3f1e958d8 298 SUPERFAMILY SSF53335 69 254 9.09E-36 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_21320 55c01fddc3518039bcdc04c3f1e958d8 298 Pfam PF02475 Met-10+ like-protein 69 252 1.1E-27 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 STK_21320 55c01fddc3518039bcdc04c3f1e958d8 298 Gene3D G3DSA:3.40.50.150 127 296 3.8E-24 T 23-10-2018 STK_21320 55c01fddc3518039bcdc04c3f1e958d8 298 Gene3D G3DSA:3.30.300.110 39 126 1.1E-8 T 23-10-2018 STK_06780 330f59e14682c3283bfc3bbb4ff43f5e 434 Pfam PF01385 Probable transposase 170 284 4.6E-36 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 STK_06780 330f59e14682c3283bfc3bbb4ff43f5e 434 Pfam PF07282 Putative transposase DNA-binding domain 300 367 2.6E-19 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_07760 6face12cab20e9a0f1ea9f26822522b0 222 SUPERFAMILY SSF117396 1 216 6.8E-53 T 23-10-2018 IPR036520 UPF0759 superfamily STK_07760 6face12cab20e9a0f1ea9f26822522b0 222 Gene3D G3DSA:3.20.20.410 1 219 2.0E-42 T 23-10-2018 IPR036520 UPF0759 superfamily STK_07760 6face12cab20e9a0f1ea9f26822522b0 222 Pfam PF01904 Protein of unknown function DUF72 18 212 9.7E-33 T 23-10-2018 IPR002763 Protein of unknown function DUF72 STK_22010 9b00794e7a624f4373bb801c70f71088 273 Gene3D G3DSA:3.40.50.1980 18 136 2.3E-24 T 23-10-2018 STK_22010 9b00794e7a624f4373bb801c70f71088 273 Pfam PF01497 Periplasmic binding protein 21 239 1.6E-19 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain STK_22010 9b00794e7a624f4373bb801c70f71088 273 SUPERFAMILY SSF53807 12 266 3.92E-44 T 23-10-2018 STK_22010 9b00794e7a624f4373bb801c70f71088 273 Gene3D G3DSA:3.40.50.1980 137 264 1.3E-16 T 23-10-2018 STK_21135 f5f025d0201a94378680fa3da496b18e 98 Pfam PF01910 Thiamine-binding protein 5 95 1.9E-26 T 23-10-2018 IPR002767 Thiamine-binding protein STK_21135 f5f025d0201a94378680fa3da496b18e 98 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 3 98 5.3E-22 T 23-10-2018 IPR002767 Thiamine-binding protein STK_21135 f5f025d0201a94378680fa3da496b18e 98 Gene3D G3DSA:3.30.70.930 2 98 4.1E-26 T 23-10-2018 IPR029756 MTH1187/YkoF-like STK_21135 f5f025d0201a94378680fa3da496b18e 98 SUPERFAMILY SSF89957 3 97 4.06E-25 T 23-10-2018 IPR029756 MTH1187/YkoF-like STK_19720 8cd872122a42a7a0c5ad385a9c1eea07 320 SUPERFAMILY SSF51735 2 303 1.35E-83 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_19720 8cd872122a42a7a0c5ad385a9c1eea07 320 Gene3D G3DSA:3.90.25.10 180 295 3.2E-96 T 23-10-2018 STK_19720 8cd872122a42a7a0c5ad385a9c1eea07 320 Pfam PF16363 GDP-mannose 4,6 dehydratase 3 270 2.0E-61 T 23-10-2018 IPR016040 NAD(P)-binding domain STK_19720 8cd872122a42a7a0c5ad385a9c1eea07 320 Gene3D G3DSA:3.40.50.720 2 287 3.2E-96 T 23-10-2018 STK_14430 b361ec0ef7e6da823998a22ff0ff31b5 510 Pfam PF00437 Type II/IV secretion system protein 204 361 1.2E-10 T 23-10-2018 IPR001482 Type II/IV secretion system protein STK_14430 b361ec0ef7e6da823998a22ff0ff31b5 510 Gene3D G3DSA:3.40.50.1010 2 130 1.4E-15 T 23-10-2018 STK_14430 b361ec0ef7e6da823998a22ff0ff31b5 510 SUPERFAMILY SSF88723 3 126 9.12E-8 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_14430 b361ec0ef7e6da823998a22ff0ff31b5 510 SUPERFAMILY SSF52540 129 427 2.52E-29 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_14430 b361ec0ef7e6da823998a22ff0ff31b5 510 SMART SM00382 249 371 0.0029 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_14430 b361ec0ef7e6da823998a22ff0ff31b5 510 Gene3D G3DSA:3.40.50.300 230 453 6.6E-22 T 23-10-2018 STK_01570 72c32b5a7278f9a9660589ddf87cf713 204 Pfam PF06157 Protein of unknown function (DUF973) 4 200 2.6E-22 T 23-10-2018 IPR009321 Protein of unknown function DUF973 STK_04160 284de9680cd01989913650b7ca69262f 151 Gene3D G3DSA:1.10.1200.60 91 148 2.3E-19 T 23-10-2018 IPR015974 Ribosomal protein L19/L19e, domain 3 GO:0003735|GO:0006412 STK_04160 284de9680cd01989913650b7ca69262f 151 SMART SM01416 3 147 2.3E-71 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04160 284de9680cd01989913650b7ca69262f 151 Gene3D G3DSA:1.10.1650.10 1 56 1.3E-18 T 23-10-2018 IPR015972 Ribosomal protein L19/L19e, domain 1 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04160 284de9680cd01989913650b7ca69262f 151 Pfam PF01280 Ribosomal protein L19e 4 145 1.2E-46 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04160 284de9680cd01989913650b7ca69262f 151 Hamap MF_01475 50S ribosomal protein L19e [rpl19e]. 3 150 24.985 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04160 284de9680cd01989913650b7ca69262f 151 SUPERFAMILY SSF48140 4 144 2.62E-46 T 23-10-2018 IPR035970 Ribosomal protein L19/L19e superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_24670 88a0b350e0ef8ad85f75fb2d81c7105c 286 SUPERFAMILY SSF50447 128 201 2.07E-11 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily STK_24670 88a0b350e0ef8ad85f75fb2d81c7105c 286 Gene3D G3DSA:2.40.30.10 128 206 8.4E-13 T 23-10-2018 STK_19670 6840362ec188b4809b7cc61bc9fce35f 244 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 106 165 1.4E-10 T 23-10-2018 IPR006342 Methyltransferase FkbM STK_19670 6840362ec188b4809b7cc61bc9fce35f 244 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 101 157 4.3E-8 T 23-10-2018 STK_19670 6840362ec188b4809b7cc61bc9fce35f 244 SUPERFAMILY SSF53335 63 231 2.52E-22 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_19670 6840362ec188b4809b7cc61bc9fce35f 244 Gene3D G3DSA:3.40.50.150 96 238 2.6E-15 T 23-10-2018 STK_06884 9f2148911860bccf54922a689a5f8d43 123 Pfam PF01850 PIN domain 6 116 2.4E-8 T 23-10-2018 IPR002716 PIN domain STK_06884 9f2148911860bccf54922a689a5f8d43 123 SUPERFAMILY SSF88723 4 122 1.82E-28 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_06884 9f2148911860bccf54922a689a5f8d43 123 Gene3D G3DSA:3.40.50.1010 2 123 2.4E-32 T 23-10-2018 STK_23700 d1071a0903a54563ada07f0c2ea45367 144 Pfam PF02915 Rubrerythrin 11 136 1.7E-27 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 STK_23700 d1071a0903a54563ada07f0c2ea45367 144 Gene3D G3DSA:1.20.1260.10 1 144 1.3E-51 T 23-10-2018 IPR012347 Ferritin-like STK_23700 d1071a0903a54563ada07f0c2ea45367 144 SUPERFAMILY SSF47240 4 143 3.54E-40 T 23-10-2018 IPR009078 Ferritin-like superfamily STK_06090 ab74736ddc5e44a275c40aa0befcf908 327 Pfam PF01061 ABC-2 type transporter 107 294 4.8E-13 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 STK_13110 e6567c7c43f7e9622c366ff20acf3788 168 Pfam PF06939 Protein of unknown function (DUF1286) 1 112 2.4E-46 T 23-10-2018 IPR009705 Sulfolobus virus STSV1, Orf8 STK_20930 907d630cc53b19ed5b5484cd1baa0062 157 SUPERFAMILY SSF55729 7 143 4.25E-31 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase STK_20930 907d630cc53b19ed5b5484cd1baa0062 157 Pfam PF00583 Acetyltransferase (GNAT) family 35 132 4.7E-17 T 23-10-2018 IPR000182 GNAT domain STK_20930 907d630cc53b19ed5b5484cd1baa0062 157 Gene3D G3DSA:3.40.630.30 6 156 1.2E-43 T 23-10-2018 STK_08810 cc6eae240ebd1bfc88ebcd24f641b991 232 Pfam PF01206 Sulfurtransferase TusA 16 84 3.2E-16 T 23-10-2018 IPR001455 TusA-like domain STK_08810 cc6eae240ebd1bfc88ebcd24f641b991 232 Gene3D G3DSA:3.30.110.40 12 84 2.5E-15 T 23-10-2018 IPR036868 TusA-like domain superfamily STK_08810 cc6eae240ebd1bfc88ebcd24f641b991 232 SUPERFAMILY SSF64307 9 82 5.36E-16 T 23-10-2018 IPR036868 TusA-like domain superfamily STK_18420 1fced5b2bad2a1ca25ee95d87717129f 355 Pfam PF03916 Polysulphide reductase, NrfD 26 265 1.6E-10 T 23-10-2018 IPR005614 NrfD family STK_01210 15dfeb6b35ab72d2487b90c298306412 259 Pfam PF13478 XdhC Rossmann domain 78 216 2.1E-20 T 23-10-2018 IPR027051 XdhC Rossmann domain STK_01210 15dfeb6b35ab72d2487b90c298306412 259 Gene3D G3DSA:3.40.50.720 77 237 3.1E-21 T 23-10-2018 STK_07710 652d9e82f3c777a45abfee6f24e8b6a8 260 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 13 258 2.4E-41 T 23-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 STK_07710 652d9e82f3c777a45abfee6f24e8b6a8 260 Gene3D G3DSA:3.40.830.10 3 259 7.4E-59 T 23-10-2018 STK_07710 652d9e82f3c777a45abfee6f24e8b6a8 260 PIRSF PIRSF006157 5 260 2.6E-71 T 23-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 STK_07710 652d9e82f3c777a45abfee6f24e8b6a8 260 SUPERFAMILY SSF53213 13 258 3.53E-63 T 23-10-2018 STK_11255 8cd20d66c01f0d8f641f969b80ff66db 84 Hamap MF_00794 Putative antitoxin . 6 80 16.375 T 23-10-2018 IPR003847 Putative antitoxin STK_11255 8cd20d66c01f0d8f641f969b80ff66db 84 ProDom PD188822 UPF0330 AF1997 ST1125.1 AF1689 AF1478 C1_0043 PYRAB04040 PF1222 MM2475 MA1514 6 58 2.0E-13 T 23-10-2018 IPR003847 Putative antitoxin STK_11255 8cd20d66c01f0d8f641f969b80ff66db 84 Pfam PF02697 Putative antitoxin 7 72 4.8E-22 T 23-10-2018 IPR003847 Putative antitoxin STK_00510 3c9cf6954528ecf5e6375681bd14b37a 219 Pfam PF04967 HTH DNA binding domain 154 205 3.5E-21 T 23-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain STK_19420 c90c76e472f08a1aa4cbfeb5fa65aa83 352 Pfam PF14210 Domain of unknown function (DUF4322) 2 67 7.5E-43 T 23-10-2018 IPR025471 Domain of unknown function DUF4322 STK_19420 c90c76e472f08a1aa4cbfeb5fa65aa83 352 Pfam PF01609 Transposase DDE domain 96 299 1.0E-7 T 23-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 STK_01150 e197ab9b1b676f8816608e082b097cc0 269 Pfam PF06053 Domain of unknown function (DUF929) 19 258 1.2E-86 T 23-10-2018 IPR009272 Protein of unknown function DUF929 STK_12590 872977e0f2b2b259618fecbb87789bfb 831 SUPERFAMILY SSF51998 198 785 5.19E-156 T 23-10-2018 STK_12590 872977e0f2b2b259618fecbb87789bfb 831 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 119 782 1.3E-241 T 23-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 STK_12590 872977e0f2b2b259618fecbb87789bfb 831 Pfam PF02867 Ribonucleotide reductase, barrel domain 199 772 1.7E-187 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 STK_12590 872977e0f2b2b259618fecbb87789bfb 831 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 113 196 4.6E-29 T 23-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 STK_12590 872977e0f2b2b259618fecbb87789bfb 831 PRINTS PR01183 Ribonucleotide reductase large chain signature 404 415 4.2E-42 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 STK_12590 872977e0f2b2b259618fecbb87789bfb 831 PRINTS PR01183 Ribonucleotide reductase large chain signature 514 536 4.2E-42 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 STK_12590 872977e0f2b2b259618fecbb87789bfb 831 PRINTS PR01183 Ribonucleotide reductase large chain signature 542 565 4.2E-42 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 STK_12590 872977e0f2b2b259618fecbb87789bfb 831 PRINTS PR01183 Ribonucleotide reductase large chain signature 626 653 4.2E-42 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 STK_12590 872977e0f2b2b259618fecbb87789bfb 831 PRINTS PR01183 Ribonucleotide reductase large chain signature 476 499 4.2E-42 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 STK_12590 872977e0f2b2b259618fecbb87789bfb 831 PRINTS PR01183 Ribonucleotide reductase large chain signature 279 298 4.2E-42 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 STK_12590 872977e0f2b2b259618fecbb87789bfb 831 Gene3D G3DSA:3.20.70.20 106 365 2.8E-78 T 23-10-2018 STK_12590 872977e0f2b2b259618fecbb87789bfb 831 Gene3D G3DSA:3.20.70.20 367 787 2.7E-141 T 23-10-2018 STK_12590 872977e0f2b2b259618fecbb87789bfb 831 SUPERFAMILY SSF48168 19 195 1.83E-30 T 23-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 STK_12590 872977e0f2b2b259618fecbb87789bfb 831 Pfam PF03477 ATP cone domain 15 94 5.4E-7 T 23-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 STK_12590 872977e0f2b2b259618fecbb87789bfb 831 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 116 770 2.3E-119 T 23-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 STK_23950 b4f61799ba37b869d6b560f10688a1f7 179 SUPERFAMILY SSF49503 54 179 1.66E-21 T 23-10-2018 IPR008972 Cupredoxin STK_23950 b4f61799ba37b869d6b560f10688a1f7 179 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 121 172 - T 23-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 STK_23520 6e6ad3c42cb68cd2e47be9fd1f0447bf 258 Gene3D G3DSA:3.90.550.10 1 255 4.8E-58 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_23520 6e6ad3c42cb68cd2e47be9fd1f0447bf 258 SUPERFAMILY SSF53448 4 247 1.55E-49 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_23520 6e6ad3c42cb68cd2e47be9fd1f0447bf 258 Pfam PF00483 Nucleotidyl transferase 4 246 2.2E-28 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 STK_23880 98b775c181fe4a0260724e2693d5ba17 137 ProSitePatterns PS01117 MarR-type HTH domain signature. 58 92 - T 23-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site STK_23880 98b775c181fe4a0260724e2693d5ba17 137 SMART SM00347 20 119 1.1E-19 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 STK_23880 98b775c181fe4a0260724e2693d5ba17 137 Gene3D G3DSA:1.10.10.10 2 131 5.1E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_23880 98b775c181fe4a0260724e2693d5ba17 137 SUPERFAMILY SSF46785 4 119 2.67E-26 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_23880 98b775c181fe4a0260724e2693d5ba17 137 Pfam PF01047 MarR family 27 84 4.9E-15 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 STK_23880 98b775c181fe4a0260724e2693d5ba17 137 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 95 1.4E-6 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 STK_23880 98b775c181fe4a0260724e2693d5ba17 137 PRINTS PR00598 Bacterial regulatory protein MarR family signature 60 75 1.4E-6 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 STK_17090 4cc33d303afce8c7d9f86f93400786f0 550 Pfam PF07690 Major Facilitator Superfamily 212 423 6.2E-17 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_17090 4cc33d303afce8c7d9f86f93400786f0 550 Pfam PF07690 Major Facilitator Superfamily 14 200 1.0E-28 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_17090 4cc33d303afce8c7d9f86f93400786f0 550 Gene3D G3DSA:1.20.1250.20 7 225 9.9E-32 T 23-10-2018 STK_17090 4cc33d303afce8c7d9f86f93400786f0 550 SUPERFAMILY SSF103473 3 544 3.14E-53 T 23-10-2018 IPR036259 MFS transporter superfamily STK_11000 12fd07bdd5f8f6e86081019d7fd60025 107 Gene3D G3DSA:3.30.460.10 1 102 4.5E-17 T 23-10-2018 STK_11000 12fd07bdd5f8f6e86081019d7fd60025 107 SUPERFAMILY SSF81301 21 96 1.07E-14 T 23-10-2018 STK_11000 12fd07bdd5f8f6e86081019d7fd60025 107 Pfam PF01909 Nucleotidyltransferase domain 20 71 1.6E-11 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_18350 c14d7ea201e5d94a48d11e449d176d07 137 Gene3D G3DSA:3.30.1460.10 2 137 8.1E-19 T 23-10-2018 STK_18350 c14d7ea201e5d94a48d11e449d176d07 137 Pfam PF10061 Uncharacterized conserved protein (DUF2299) 6 135 1.2E-38 T 23-10-2018 IPR018747 Protein of unknown function DUF2299 STK_04645 745e4fef28ad95dacdebb1e3edd67d97 176 SUPERFAMILY SSF52540 8 161 4.85E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_04645 745e4fef28ad95dacdebb1e3edd67d97 176 Gene3D G3DSA:3.40.50.300 4 174 5.9E-14 T 23-10-2018 STK_14350 b239e37d3241d261e7e5a02f688f83fa 191 Pfam PF01991 ATP synthase (E/31 kDa) subunit 17 189 7.4E-6 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 STK_14350 b239e37d3241d261e7e5a02f688f83fa 191 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 2 190 12.098 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 STK_14350 b239e37d3241d261e7e5a02f688f83fa 191 Gene3D G3DSA:3.30.2320.30 82 190 3.9E-14 T 23-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 STK_14350 b239e37d3241d261e7e5a02f688f83fa 191 SUPERFAMILY SSF160527 82 190 8.89E-20 T 23-10-2018 STK_19070 ae20706f1b468b8758fcc10aeb7c0cfe 244 Gene3D G3DSA:1.10.10.10 48 96 1.7E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_19070 ae20706f1b468b8758fcc10aeb7c0cfe 244 Pfam PF13384 Homeodomain-like domain 52 90 7.7E-8 T 23-10-2018 STK_19070 ae20706f1b468b8758fcc10aeb7c0cfe 244 SUPERFAMILY SSF46689 49 132 8.51E-10 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 STK_11450 0e74c01e272a638b0a77ac3c3e292361 409 Pfam PF13175 AAA ATPase domain 2 351 5.2E-32 T 23-10-2018 STK_11450 0e74c01e272a638b0a77ac3c3e292361 409 PIRSF PIRSF034888 1 409 2.0E-125 T 23-10-2018 IPR014592 Predicted P-loop ATP-binding protein, VCA0200 STK_11450 0e74c01e272a638b0a77ac3c3e292361 409 SUPERFAMILY SSF52540 2 368 1.13E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_13795 4f330761f6c32aae9220ccaa085a8ccc 71 SUPERFAMILY SSF64307 6 70 1.57E-15 T 23-10-2018 IPR036868 TusA-like domain superfamily STK_13795 4f330761f6c32aae9220ccaa085a8ccc 71 Gene3D G3DSA:3.30.110.40 5 70 1.1E-11 T 23-10-2018 IPR036868 TusA-like domain superfamily STK_13795 4f330761f6c32aae9220ccaa085a8ccc 71 Pfam PF01206 Sulfurtransferase TusA 7 69 4.4E-13 T 23-10-2018 IPR001455 TusA-like domain STK_00373 abd23622baada573ff2d03dad85e5cc8 58 Gene3D G3DSA:1.20.120.330 1 55 5.5E-13 T 23-10-2018 STK_00373 abd23622baada573ff2d03dad85e5cc8 58 SUPERFAMILY SSF81593 2 50 3.85E-13 T 23-10-2018 STK_00373 abd23622baada573ff2d03dad85e5cc8 58 Pfam PF05168 HEPN domain 3 50 4.1E-12 T 23-10-2018 IPR007842 HEPN domain STK_18005 5fdfd1d2ffe3667349e7bd291b8c6dc8 92 Pfam PF07362 Post-segregation antitoxin CcdA 23 72 2.7E-6 T 23-10-2018 IPR009956 Post-segregation antitoxin CcdA STK_23840 0a2c2028e64603e0dfe05201cdfa53be 353 SUPERFAMILY SSF103473 2 156 5.49E-5 T 23-10-2018 IPR036259 MFS transporter superfamily STK_01650 748f62301cd2b4212cf37cbe21dfb9a4 323 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 179 192 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 STK_01650 748f62301cd2b4212cf37cbe21dfb9a4 323 Gene3D G3DSA:3.40.640.10 28 223 2.9E-51 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 STK_01650 748f62301cd2b4212cf37cbe21dfb9a4 323 SUPERFAMILY SSF53383 11 307 1.1E-37 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase STK_01650 748f62301cd2b4212cf37cbe21dfb9a4 323 Gene3D G3DSA:3.90.1150.10 18 305 2.9E-51 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 STK_01650 748f62301cd2b4212cf37cbe21dfb9a4 323 Pfam PF00155 Aminotransferase class I and II 18 302 5.0E-11 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 STK_16520 0a602421cac4d44c86b52b6c1cecd9a2 488 Pfam PF03109 ABC1 family 99 214 4.2E-27 T 23-10-2018 IPR004147 UbiB domain STK_16520 0a602421cac4d44c86b52b6c1cecd9a2 488 SUPERFAMILY SSF56112 80 313 9.58E-24 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily STK_18470 7d883a3135ade36d31efc2da8c7c3ae4 176 SUPERFAMILY SSF102405 1 165 1.47E-26 T 23-10-2018 STK_18470 7d883a3135ade36d31efc2da8c7c3ae4 176 Gene3D G3DSA:3.40.50.450 3 166 8.9E-20 T 23-10-2018 STK_07340 27c6b7e5fea7501482cb8e06e11d677e 186 SUPERFAMILY SSF53323 4 150 7.72E-28 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 STK_07340 27c6b7e5fea7501482cb8e06e11d677e 186 Gene3D G3DSA:3.40.920.10 1 180 1.2E-36 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 STK_07340 27c6b7e5fea7501482cb8e06e11d677e 186 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 165 2.2E-29 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 STK_12440 1e8c63233d08b4bdfaa746ad1c4114b5 400 Pfam PF04894 Archaeal Nre, N-terminal 9 281 6.4E-96 T 23-10-2018 IPR006978 Archaeal Nre, N-terminal STK_12440 1e8c63233d08b4bdfaa746ad1c4114b5 400 Hamap MF_02096 DNA repair protein. 1 397 34.735 T 23-10-2018 IPR033167 Archaeal Nre GO:0006281 STK_12440 1e8c63233d08b4bdfaa746ad1c4114b5 400 Pfam PF04895 Archaeal Nre, C-terminal 297 397 8.4E-33 T 23-10-2018 IPR006979 Archaeal Nre, C-terminal STK_00740 a9f4b3d10f0b9f7e19fd7879547f18a7 131 SUPERFAMILY SSF55961 2 130 2.5E-11 T 23-10-2018 STK_00740 a9f4b3d10f0b9f7e19fd7879547f18a7 131 Gene3D G3DSA:3.30.530.20 1 131 4.6E-5 T 23-10-2018 IPR023393 START-like domain superfamily STK_00740 a9f4b3d10f0b9f7e19fd7879547f18a7 131 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 5 131 3.1E-35 T 23-10-2018 IPR010419 Carbon monoxide dehydrogenase subunit G STK_11530 277d216d8731b5876becfc764640f72e 683 Pfam PF07728 AAA domain (dynein-related subfamily) 397 573 3.0E-11 T 23-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 STK_11530 277d216d8731b5876becfc764640f72e 683 SMART SM00382 394 579 2.7E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_11530 277d216d8731b5876becfc764640f72e 683 SUPERFAMILY SSF52540 385 653 2.77E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_18340 16ded9633d0f543cbf4b2628e2b762e6 113 SUPERFAMILY SSF75169 1 113 6.56E-19 T 23-10-2018 IPR027396 DsrEFH-like STK_18340 16ded9633d0f543cbf4b2628e2b762e6 113 Pfam PF02635 DsrE/DsrF-like family 4 113 1.6E-12 T 23-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein STK_18340 16ded9633d0f543cbf4b2628e2b762e6 113 Gene3D G3DSA:3.40.1260.10 1 113 8.4E-12 T 23-10-2018 IPR027396 DsrEFH-like STK_23830 22bfc6778b94e3503119eeeca3fa44a2 182 Pfam PF01661 Macro domain 19 131 1.7E-36 T 23-10-2018 IPR002589 Macro domain STK_23830 22bfc6778b94e3503119eeeca3fa44a2 182 SUPERFAMILY SSF52949 1 172 1.85E-57 T 23-10-2018 STK_23830 22bfc6778b94e3503119eeeca3fa44a2 182 SMART SM00506 2 132 2.8E-50 T 23-10-2018 IPR002589 Macro domain STK_23830 22bfc6778b94e3503119eeeca3fa44a2 182 Gene3D G3DSA:3.40.220.10 1 169 6.5E-58 T 23-10-2018 STK_02220 b3ed6f0910ababa2c721aba9af7e4881 328 SUPERFAMILY SSF56281 28 315 1.86E-26 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_02220 b3ed6f0910ababa2c721aba9af7e4881 328 Gene3D G3DSA:3.60.15.10 9 164 3.6E-19 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like STK_24970 0fec274592e86dfc38b90ea3d6e64ce0 253 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 72 151 2.1E-21 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_20854 65e9e136d66f3a141961c829a0b36cb0 89 Pfam PF16795 Archaeal phage integrase 1 45 4.7E-8 T 23-10-2018 IPR031857 Integrase SSV1, C-terminal STK_08020 5f4e6bc84dd2626bc26aee9d2512f39f 110 Pfam PF00005 ABC transporter 45 81 1.8E-6 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_08020 5f4e6bc84dd2626bc26aee9d2512f39f 110 SUPERFAMILY SSF52540 44 89 7.62E-8 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_08020 5f4e6bc84dd2626bc26aee9d2512f39f 110 Gene3D G3DSA:3.40.50.300 40 110 2.3E-10 T 23-10-2018 STK_10630 7981c045f4cd21f2a1bfffb0d32146ac 292 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 3 286 2.3E-72 T 23-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 STK_10630 7981c045f4cd21f2a1bfffb0d32146ac 292 SUPERFAMILY SSF51556 1 288 1.02E-51 T 23-10-2018 IPR032466 Metal-dependent hydrolase STK_10630 7981c045f4cd21f2a1bfffb0d32146ac 292 Gene3D G3DSA:3.20.20.140 1 292 3.9E-62 T 23-10-2018 STK_06950 8beb68f13975d06f59c9805e04725769 509 Pfam PF13520 Amino acid permease 46 470 3.2E-16 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_06950 8beb68f13975d06f59c9805e04725769 509 Gene3D G3DSA:1.20.1740.10 15 502 1.1E-9 T 23-10-2018 STK_06950 8beb68f13975d06f59c9805e04725769 509 PIRSF PIRSF006060 4 508 8.9E-27 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 STK_10860 9d2a88a3551f6c5230a8ee3a597787a2 144 Pfam PF01909 Nucleotidyltransferase domain 36 121 1.8E-11 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_10860 9d2a88a3551f6c5230a8ee3a597787a2 144 Gene3D G3DSA:3.30.460.10 17 133 4.8E-12 T 23-10-2018 STK_10860 9d2a88a3551f6c5230a8ee3a597787a2 144 SUPERFAMILY SSF81301 24 104 7.05E-13 T 23-10-2018 STK_03080 3813bb96b3f93e6ccdd71cfe2cc21d83 107 SUPERFAMILY SSF57783 1 80 1.87E-19 T 23-10-2018 STK_03080 3813bb96b3f93e6ccdd71cfe2cc21d83 107 Pfam PF05129 Transcription elongation factor Elf1 like 3 75 2.1E-18 T 23-10-2018 IPR007808 Transcription elongation factor 1 STK_07020 604038f8dd5ec429b41128380435192a 482 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 285 476 1.4E-17 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 STK_07020 604038f8dd5ec429b41128380435192a 482 Gene3D G3DSA:1.10.3720.10 254 475 5.7E-13 T 23-10-2018 IPR035906 MetI-like superfamily STK_07020 604038f8dd5ec429b41128380435192a 482 SUPERFAMILY SSF161098 263 460 8.63E-14 T 23-10-2018 IPR035906 MetI-like superfamily STK_03360 7457ec50a4a0e07fd74d2c425ab2df8a 153 Pfam PF09895 RecB-family nuclease (DUF2122) 38 142 6.7E-38 T 23-10-2018 IPR018665 Protein of unknown function DUF2122, RecB-family nuclease-related STK_03600 9ace56975d846c8b5057ef2c0ed8f9d8 212 SUPERFAMILY SSF52507 14 199 1.57E-49 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 STK_03600 9ace56975d846c8b5057ef2c0ed8f9d8 212 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 14 200 32.614 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like STK_03600 9ace56975d846c8b5057ef2c0ed8f9d8 212 Pfam PF02441 Flavoprotein 15 179 7.6E-28 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 STK_03600 9ace56975d846c8b5057ef2c0ed8f9d8 212 Gene3D G3DSA:3.40.50.1950 11 205 1.5E-66 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 STK_03600 9ace56975d846c8b5057ef2c0ed8f9d8 212 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 16 198 7.5E-57 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like STK_17000 592db98ae968e5503e2f6dbc22342d51 294 Pfam PF06053 Domain of unknown function (DUF929) 12 292 6.1E-90 T 23-10-2018 IPR009272 Protein of unknown function DUF929 STK_16020 b294e521a368dfd873ee0bd44557a72f 260 Pfam PF12644 Protein of unknown function (DUF3782) 103 182 6.4E-21 T 23-10-2018 IPR024271 Protein of unknown function DUF3782 STK_16020 b294e521a368dfd873ee0bd44557a72f 260 Pfam PF07788 PD-(D/E)XK nuclease superfamily 183 256 9.8E-36 T 23-10-2018 IPR012431 PD-(D/E)XK nuclease STK_18860 71373265d025f1691f9f0b0e78936ff6 352 Pfam PF04055 Radical SAM superfamily 45 218 1.5E-10 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_18860 71373265d025f1691f9f0b0e78936ff6 352 SUPERFAMILY SSF102114 36 274 5.36E-30 T 23-10-2018 STK_18860 71373265d025f1691f9f0b0e78936ff6 352 SMART SM00729 37 264 7.2E-22 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 STK_18860 71373265d025f1691f9f0b0e78936ff6 352 Gene3D G3DSA:3.20.20.70 29 272 1.4E-19 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_08120 39e8b169828e82aa7089fe2574a56dbe 136 Gene3D G3DSA:3.30.530.20 1 136 3.7E-56 T 23-10-2018 IPR023393 START-like domain superfamily STK_08120 39e8b169828e82aa7089fe2574a56dbe 136 Pfam PF11485 Protein of unknown function (DUF3211) 2 136 2.6E-40 T 23-10-2018 IPR021578 Protein of unknown function DUF3211 STK_08120 39e8b169828e82aa7089fe2574a56dbe 136 SUPERFAMILY SSF55961 1 121 2.56E-5 T 23-10-2018 STK_22300 0da2dba2d11622236c77b13151249d3e 326 Pfam PF05598 Transposase domain (DUF772) 43 107 5.9E-8 T 23-10-2018 IPR008490 Transposase InsH, N-terminal STK_26410 5b0de14f0322038a5a680ae7f6de3111 298 TIGRFAM TIGR03876 cas_csaX: CRISPR type I-A/APERN-associated protein CsaX 7 265 8.0E-129 T 23-10-2018 IPR022297 CRISPR-associated protein, CsaX STK_15220 6c9d5200ad96982d4b04b1f799482435 448 SUPERFAMILY SSF111283 3 444 7.32E-90 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 STK_15220 6c9d5200ad96982d4b04b1f799482435 448 PIRSF PIRSF004919 1 446 2.1E-130 T 23-10-2018 IPR025502 TldD STK_15220 6c9d5200ad96982d4b04b1f799482435 448 Pfam PF01523 Putative modulator of DNA gyrase 14 301 2.2E-39 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 STK_19380 aff6feab06f8497524fdf98088da8f4e 441 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 249 328 5.6E-21 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_25430 955a2c933714910722bc5c8575491919 323 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 296 8.4E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 STK_25430 955a2c933714910722bc5c8575491919 323 SMART SM00382 45 232 1.1E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_25430 955a2c933714910722bc5c8575491919 323 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 STK_25430 955a2c933714910722bc5c8575491919 323 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 315 3.7E-25 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 STK_25430 955a2c933714910722bc5c8575491919 323 Gene3D G3DSA:3.40.50.300 22 323 1.8E-92 T 23-10-2018 STK_25430 955a2c933714910722bc5c8575491919 323 Pfam PF00005 ABC transporter 36 183 1.3E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_25430 955a2c933714910722bc5c8575491919 323 SUPERFAMILY SSF52540 23 254 1.39E-68 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_06500 6f746548cd7230aef86b94e91c7fd458 154 Gene3D G3DSA:1.20.120.330 46 154 1.2E-7 T 23-10-2018 STK_06500 6f746548cd7230aef86b94e91c7fd458 154 Pfam PF05942 Archaeal PaREP1/PaREP8 family 47 116 7.6E-7 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_05367 6c6cefc3b1a26ce09b2262e8b0726ecf 58 SUPERFAMILY SSF47598 1 42 1.41E-7 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 STK_05367 6c6cefc3b1a26ce09b2262e8b0726ecf 58 Gene3D G3DSA:1.10.1220.10 2 45 9.6E-6 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 STK_05367 6c6cefc3b1a26ce09b2262e8b0726ecf 58 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 39 3.6E-9 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 STK_11804 a4b22dd2f60b2cb9ff45cd8948ac718e 119 SUPERFAMILY SSF52540 3 113 7.83E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_11804 a4b22dd2f60b2cb9ff45cd8948ac718e 119 Gene3D G3DSA:3.40.50.300 1 118 2.1E-17 T 23-10-2018 STK_00016 b056ed9bf5e483bf726032e2bb51a8e5 71 SUPERFAMILY SSF81301 2 51 8.59E-6 T 23-10-2018 STK_00016 b056ed9bf5e483bf726032e2bb51a8e5 71 Gene3D G3DSA:3.30.460.10 1 67 2.8E-5 T 23-10-2018 STK_10755 a0b5268e728af43ad20d126c2ed1ded5 51 Pfam PF06467 MYM-type Zinc finger with FCS sequence motif 10 45 1.5E-7 T 23-10-2018 IPR010507 Zinc finger, MYM-type GO:0008270 STK_10755 a0b5268e728af43ad20d126c2ed1ded5 51 SMART SM00746 12 49 4.3E-6 T 23-10-2018 IPR011017 TRASH domain STK_02435 f9ad3de9ab2d6ea13fc93b3feed162bd 90 SUPERFAMILY SSF55021 4 84 3.9E-20 T 23-10-2018 STK_02435 f9ad3de9ab2d6ea13fc93b3feed162bd 90 Pfam PF13740 ACT domain 5 77 1.3E-15 T 23-10-2018 STK_02435 f9ad3de9ab2d6ea13fc93b3feed162bd 90 Hamap MF_01054 UPF0237 protein . 2 90 24.044 T 23-10-2018 IPR022986 Uncharacterised protein family UPF0237, ACT-type STK_02435 f9ad3de9ab2d6ea13fc93b3feed162bd 90 Gene3D G3DSA:3.30.70.260 1 90 3.3E-25 T 23-10-2018 STK_19165 db110562991c87ff5d2cbc7fbe44c826 111 SUPERFAMILY SSF53850 1 104 3.08E-7 T 23-10-2018 STK_19165 db110562991c87ff5d2cbc7fbe44c826 111 Gene3D G3DSA:3.40.190.10 1 111 1.8E-8 T 23-10-2018 STK_16300 b0555e869f8fca563c08cc49b3e57ade 222 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 9 75 2.8E-25 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal STK_16300 b0555e869f8fca563c08cc49b3e57ade 222 Gene3D G3DSA:1.10.10.10 1 99 7.2E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_16300 b0555e869f8fca563c08cc49b3e57ade 222 SUPERFAMILY SSF46785 3 96 3.47E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_08750 39e1df73663258a2b375e464be1537db 177 Pfam PF04173 TQO small subunit DoxD 9 166 5.2E-65 T 23-10-2018 IPR007301 TQO small subunit DoxD KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 STK_15860 c9828c2f5e03b8947ee49884fc1fdb4b 119 Pfam PF06348 Protein of unknown function (DUF1059) 62 117 1.7E-22 T 23-10-2018 IPR009409 Protein of unknown function DUF1059 STK_15860 c9828c2f5e03b8947ee49884fc1fdb4b 119 Pfam PF06348 Protein of unknown function (DUF1059) 3 59 1.4E-23 T 23-10-2018 IPR009409 Protein of unknown function DUF1059 STK_08780 6df2a10559a08e4641ebd01ad6857794 110 SUPERFAMILY SSF75169 1 109 1.96E-20 T 23-10-2018 IPR027396 DsrEFH-like STK_08780 6df2a10559a08e4641ebd01ad6857794 110 Gene3D G3DSA:3.40.1260.10 21 108 7.2E-6 T 23-10-2018 IPR027396 DsrEFH-like STK_08780 6df2a10559a08e4641ebd01ad6857794 110 Pfam PF02635 DsrE/DsrF-like family 32 100 1.1E-6 T 23-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein STK_06200 a15430ef960705a8fefc494396bbfb28 122 Pfam PF09969 Uncharacterized conserved protein (DUF2203) 6 112 5.7E-30 T 23-10-2018 IPR018699 Protein of unknown function DUF2203 STK_06200 a15430ef960705a8fefc494396bbfb28 122 PIRSF PIRSF016498 3 122 6.8E-56 T 23-10-2018 IPR018699 Protein of unknown function DUF2203 STK_09650 639d4c92fddc2c8d6d4580ff039dafdd 322 SUPERFAMILY SSF53756 6 281 8.16E-16 T 23-10-2018 STK_09650 639d4c92fddc2c8d6d4580ff039dafdd 322 Gene3D G3DSA:3.40.50.2000 166 306 5.3E-10 T 23-10-2018 STK_09650 639d4c92fddc2c8d6d4580ff039dafdd 322 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 169 257 1.8E-8 T 23-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 STK_09650 639d4c92fddc2c8d6d4580ff039dafdd 322 Gene3D G3DSA:3.40.50.2000 3 165 1.7E-6 T 23-10-2018 STK_17360 aa23ee9f6071f8779c83818837509ed7 452 Pfam PF12679 ABC-2 family transporter protein 223 452 1.3E-18 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 STK_16310 37e0fa9228ab85dec3d819069ee75074 358 Pfam PF07690 Major Facilitator Superfamily 198 356 1.8E-18 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_16310 37e0fa9228ab85dec3d819069ee75074 358 Gene3D G3DSA:1.20.1250.20 1 180 1.4E-16 T 23-10-2018 STK_16310 37e0fa9228ab85dec3d819069ee75074 358 SUPERFAMILY SSF103473 2 358 4.53E-44 T 23-10-2018 IPR036259 MFS transporter superfamily STK_16310 37e0fa9228ab85dec3d819069ee75074 358 Gene3D G3DSA:1.20.1250.20 182 358 2.5E-21 T 23-10-2018 STK_24380 77e551b86ab4bfb947326461c12222a9 277 Pfam PF12679 ABC-2 family transporter protein 65 271 6.5E-8 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 STK_26100 706522a37d2474f150684c7d37af8f9c 369 SUPERFAMILY SSF103473 2 365 3.79E-25 T 23-10-2018 IPR036259 MFS transporter superfamily STK_26100 706522a37d2474f150684c7d37af8f9c 369 Gene3D G3DSA:1.20.1250.20 177 366 4.6E-13 T 23-10-2018 STK_26100 706522a37d2474f150684c7d37af8f9c 369 Pfam PF07690 Major Facilitator Superfamily 187 347 4.7E-9 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_26100 706522a37d2474f150684c7d37af8f9c 369 Gene3D G3DSA:1.20.1250.20 1 168 1.9E-7 T 23-10-2018 STK_19425 9ce0a0bd456ca6dc8fea34df8409d10c 73 Hamap MF_00794 Putative antitoxin . 2 73 16.395 T 23-10-2018 IPR003847 Putative antitoxin STK_19425 9ce0a0bd456ca6dc8fea34df8409d10c 73 Pfam PF02697 Putative antitoxin 3 69 3.8E-22 T 23-10-2018 IPR003847 Putative antitoxin STK_19425 9ce0a0bd456ca6dc8fea34df8409d10c 73 ProDom PD188822 UPF0330 AF1997 ST1125.1 AF1689 AF1478 C1_0043 PYRAB04040 PF1222 MM2475 MA1514 3 65 2.0E-29 T 23-10-2018 IPR003847 Putative antitoxin STK_14110 b0173745c76046781eec0f66602d4e8b 400 SUPERFAMILY SSF53383 4 395 9.89E-110 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase STK_14110 b0173745c76046781eec0f66602d4e8b 400 Pfam PF00155 Aminotransferase class I and II 30 389 3.4E-38 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 STK_14110 b0173745c76046781eec0f66602d4e8b 400 Gene3D G3DSA:3.40.640.10 65 290 6.1E-144 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 STK_14110 b0173745c76046781eec0f66602d4e8b 400 Gene3D G3DSA:3.90.1150.10 18 395 6.1E-144 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 STK_20470 f21bc2f4217a3802b64c979ef430ae1f 153 Gene3D G3DSA:3.40.50.150 1 153 2.0E-24 T 23-10-2018 STK_20470 f21bc2f4217a3802b64c979ef430ae1f 153 SUPERFAMILY SSF53335 4 146 5.78E-21 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_19060 2309ed622b7134a4f479c82ed1069132 434 Pfam PF07282 Putative transposase DNA-binding domain 300 367 2.6E-19 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_19060 2309ed622b7134a4f479c82ed1069132 434 Pfam PF01385 Probable transposase 170 284 4.6E-36 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 STK_16810 84af1faa3458e283ba0c6b4021e69105 342 Pfam PF01523 Putative modulator of DNA gyrase 134 220 2.9E-12 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 STK_16810 84af1faa3458e283ba0c6b4021e69105 342 SUPERFAMILY SSF111283 141 335 2.22E-25 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 STK_15760 84b1b4e50e3c62a36c0966cd7b132ca3 417 PIRSF PIRSF034888 1 417 2.2E-140 T 23-10-2018 IPR014592 Predicted P-loop ATP-binding protein, VCA0200 STK_15760 84b1b4e50e3c62a36c0966cd7b132ca3 417 SUPERFAMILY SSF52540 5 366 2.53E-18 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_15760 84b1b4e50e3c62a36c0966cd7b132ca3 417 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 23 350 2.2E-21 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 STK_04580 d92072c64a1c45b28d74bf25cbce2002 114 SUPERFAMILY SSF47819 5 109 2.01E-24 T 23-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 STK_04580 d92072c64a1c45b28d74bf25cbce2002 114 Pfam PF03874 RNA polymerase Rpb4 29 110 3.3E-7 T 23-10-2018 IPR005574 RNA polymerase subunit RPB4/RPC9 GO:0006352|GO:0030880 STK_04580 d92072c64a1c45b28d74bf25cbce2002 114 PIRSF PIRSF005053 1 113 6.1E-35 T 23-10-2018 IPR010924 DNA-directed RNA polymerase subunit F (Rpo4) STK_04580 d92072c64a1c45b28d74bf25cbce2002 114 Gene3D G3DSA:1.10.150.820 49 88 5.6E-23 T 23-10-2018 STK_17510 7c15a6b2f0bed0b80669162d5da02663 261 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 41 254 1.8E-38 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 STK_17510 7c15a6b2f0bed0b80669162d5da02663 261 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 131 254 2.3E-14 T 23-10-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal STK_17510 7c15a6b2f0bed0b80669162d5da02663 261 Gene3D G3DSA:3.30.70.1900 114 261 2.5E-41 T 23-10-2018 STK_05955 1037957f2840bcac3bed9dc797880ae3 94 Pfam PF02416 mttA/Hcf106 family 13 65 1.6E-10 T 23-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 STK_05955 1037957f2840bcac3bed9dc797880ae3 94 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 14 53 6.6E-16 T 23-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 STK_01340 592df67b7b403b00708ce2192e321d93 327 SUPERFAMILY SSF50022 90 277 2.85E-29 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 STK_01340 592df67b7b403b00708ce2192e321d93 327 Pfam PF00355 Rieske [2Fe-2S] domain 168 250 1.2E-6 T 23-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 STK_01340 592df67b7b403b00708ce2192e321d93 327 Gene3D G3DSA:2.102.10.10 87 292 1.7E-55 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 STK_15360 f91bd36e1bcacbde9713af214597bc63 127 Gene3D G3DSA:3.30.300.20 16 124 1.1E-11 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta STK_15360 f91bd36e1bcacbde9713af214597bc63 127 Pfam PF02566 OsmC-like protein 33 123 3.2E-12 T 23-10-2018 IPR003718 OsmC/Ohr family STK_15360 f91bd36e1bcacbde9713af214597bc63 127 SUPERFAMILY SSF82784 33 123 6.94E-15 T 23-10-2018 IPR036102 OsmC/Ohr superfamily STK_04650 3c4799150ee1aab58535a57c9655ed5f 166 Hamap MF_01117 CDP-archaeol synthase [carS]. 14 166 25.245 T 23-10-2018 IPR002726 CDP-archaeol synthase, archaea KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 STK_04650 3c4799150ee1aab58535a57c9655ed5f 166 Pfam PF01864 CDP-archaeol synthase 5 166 9.2E-38 T 23-10-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 STK_07630 4a4125f0f0040d14189e9a2cd3d996ad 960 SUPERFAMILY SSF52540 32 203 8.81E-8 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_00670 5fa519060adb570b82ae4936f56da3d9 372 Gene3D G3DSA:3.30.1540.10 215 303 9.6E-101 T 23-10-2018 STK_00670 5fa519060adb570b82ae4936f56da3d9 372 Pfam PF02515 CoA-transferase family III 3 311 3.2E-96 T 23-10-2018 IPR003673 CoA-transferase family III GO:0003824 STK_00670 5fa519060adb570b82ae4936f56da3d9 372 SUPERFAMILY SSF89796 3 367 7.59E-109 T 23-10-2018 IPR023606 CoA-transferase family III domain superfamily STK_00670 5fa519060adb570b82ae4936f56da3d9 372 Gene3D G3DSA:3.40.50.10540 3 311 9.6E-101 T 23-10-2018 IPR023606 CoA-transferase family III domain superfamily STK_10390 540da290617fa6bd15aefd375389a0d6 384 SMART SM00933 65 337 5.2E-31 T 23-10-2018 IPR018977 NurA domain STK_10390 540da290617fa6bd15aefd375389a0d6 384 Pfam PF09376 NurA domain 66 336 2.1E-27 T 23-10-2018 IPR018977 NurA domain STK_00290 9e2f598c4c3f8ea6fecb0bcb2a916105 315 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 6 272 4.9E-82 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR STK_00290 9e2f598c4c3f8ea6fecb0bcb2a916105 315 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 6 257 2.6E-39 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR STK_00290 9e2f598c4c3f8ea6fecb0bcb2a916105 315 TIGRFAM TIGR02583 DevR_archaea: CRISPR-associated protein Cas7/Csa2, subtype I-A/APERN 3 280 3.0E-111 T 23-10-2018 IPR002764 CRISPR-associated protein Cas7/Cst2/DevR, subtype I-a/Apern STK_05895 54b6f7d52dad3e9d8941b6fad647fcdd 72 SUPERFAMILY SSF47598 20 65 4.95E-11 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 STK_05895 54b6f7d52dad3e9d8941b6fad647fcdd 72 Pfam PF01402 Ribbon-helix-helix protein, copG family 22 58 4.0E-10 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 STK_05895 54b6f7d52dad3e9d8941b6fad647fcdd 72 Gene3D G3DSA:1.10.1220.10 20 62 5.8E-10 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 STK_09150 4b0a9553344cc44d00350ad76c498fdc 139 Pfam PF05942 Archaeal PaREP1/PaREP8 family 11 94 6.2E-7 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_15310 6f95da08191787227b6fe3dcaa8ba8d5 181 Gene3D G3DSA:3.40.920.10 1 180 7.9E-56 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 STK_15310 6f95da08191787227b6fe3dcaa8ba8d5 181 SUPERFAMILY SSF53323 2 180 7.19E-51 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 STK_15310 6f95da08191787227b6fe3dcaa8ba8d5 181 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 2 179 3.1E-71 T 23-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 STK_15310 6f95da08191787227b6fe3dcaa8ba8d5 181 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 174 1.4E-36 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 STK_19320 400d61c925c0d715aaf0b4d3e5909c75 185 Pfam PF01850 PIN domain 15 138 1.4E-5 T 23-10-2018 IPR002716 PIN domain STK_19320 400d61c925c0d715aaf0b4d3e5909c75 185 Gene3D G3DSA:3.40.50.1010 14 147 1.7E-13 T 23-10-2018 STK_19320 400d61c925c0d715aaf0b4d3e5909c75 185 SUPERFAMILY SSF88723 14 143 7.85E-12 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_23260 e3529271dc9df57f019b833b21cabf77 239 Pfam PF13230 Glutamine amidotransferases class-II 33 173 7.0E-5 T 23-10-2018 IPR026869 Putative glutamine amidotransferase type 2 STK_23260 e3529271dc9df57f019b833b21cabf77 239 Gene3D G3DSA:3.60.20.10 1 212 3.3E-16 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_23260 e3529271dc9df57f019b833b21cabf77 239 SUPERFAMILY SSF56235 2 167 2.12E-11 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal STK_10030 f817c84b78c8dbc4337d4ab61101a49a 270 SUPERFAMILY SSF74650 10 265 1.32E-56 T 23-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 STK_10030 f817c84b78c8dbc4337d4ab61101a49a 270 Pfam PF01263 Aldose 1-epimerase 11 264 3.0E-40 T 23-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 STK_10030 f817c84b78c8dbc4337d4ab61101a49a 270 Gene3D G3DSA:2.70.98.10 8 268 1.4E-54 T 23-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 STK_08350 32c8a32c409dc5af69bd237c87c2ad92 165 Pfam PF10015 Uncharacterized protein conserved in archaea (DUF2258) 33 106 2.1E-28 T 23-10-2018 IPR017140 Uncharacterised conserved protein UCP037214 STK_08350 32c8a32c409dc5af69bd237c87c2ad92 165 PIRSF PIRSF037214 1 165 2.3E-77 T 23-10-2018 IPR017140 Uncharacterised conserved protein UCP037214 STK_03220 afaca74433f520eecbce192b3bc8aca3 186 SUPERFAMILY SSF57783 1 41 2.32E-10 T 23-10-2018 STK_03220 afaca74433f520eecbce192b3bc8aca3 186 Gene3D G3DSA:2.20.25.10 1 39 1.3E-10 T 23-10-2018 STK_03220 afaca74433f520eecbce192b3bc8aca3 186 Pfam PF08271 TFIIB zinc-binding 1 33 9.2E-13 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type STK_06850 2931e11125b262aa3b8b9c380755a08b 233 Pfam PF06053 Domain of unknown function (DUF929) 25 233 1.4E-63 T 23-10-2018 IPR009272 Protein of unknown function DUF929 STK_04490 e6d1b9ac7dc76be5136ceb0d3cecdc35 147 SUPERFAMILY SSF55282 5 140 1.38E-37 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_04490 e6d1b9ac7dc76be5136ceb0d3cecdc35 147 Pfam PF01877 RNA binding 6 124 5.0E-30 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 STK_04490 e6d1b9ac7dc76be5136ceb0d3cecdc35 147 Gene3D G3DSA:3.30.1440.10 1 147 3.7E-41 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_20770 b2d0d85196654b8277544fdd335dee61 152 Gene3D G3DSA:3.40.630.30 1 151 1.6E-37 T 23-10-2018 STK_20770 b2d0d85196654b8277544fdd335dee61 152 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 11 141 9.0E-29 T 23-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 STK_20770 b2d0d85196654b8277544fdd335dee61 152 SUPERFAMILY SSF55729 2 144 1.75E-32 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase STK_20770 b2d0d85196654b8277544fdd335dee61 152 Pfam PF00583 Acetyltransferase (GNAT) family 13 122 6.0E-20 T 23-10-2018 IPR000182 GNAT domain STK_08650 a82ce4c587e2f9c32de1f31f838f3717 171 Pfam PF05942 Archaeal PaREP1/PaREP8 family 18 140 1.9E-20 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_15585 b937276e8243096f0de09d260fbb7cf6 86 Pfam PF16239 Domain of unknown function (DUF4898) 24 84 1.4E-8 T 23-10-2018 IPR032603 Protein of unknown function DUF4898 STK_01080 c6011b6453dbf791b5c3b65f2a91cb05 244 PRINTS PR00162 Rieske 2Fe-2S subunit signature 133 144 2.0E-8 T 23-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 STK_01080 c6011b6453dbf791b5c3b65f2a91cb05 244 PRINTS PR00162 Rieske 2Fe-2S subunit signature 166 178 2.0E-8 T 23-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 STK_01080 c6011b6453dbf791b5c3b65f2a91cb05 244 PRINTS PR00162 Rieske 2Fe-2S subunit signature 180 192 2.0E-8 T 23-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 STK_01080 c6011b6453dbf791b5c3b65f2a91cb05 244 SUPERFAMILY SSF50022 69 237 3.19E-36 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 STK_01080 c6011b6453dbf791b5c3b65f2a91cb05 244 Gene3D G3DSA:2.102.10.10 50 244 2.2E-58 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 STK_01080 c6011b6453dbf791b5c3b65f2a91cb05 244 Pfam PF00355 Rieske [2Fe-2S] domain 128 194 3.2E-11 T 23-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 STK_05500 85ad9a6f8fb709d5a16470b1540d77dd 361 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 57 259 2.9E-14 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 STK_05500 85ad9a6f8fb709d5a16470b1540d77dd 361 SUPERFAMILY SSF53649 30 359 2.06E-50 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 STK_05120 4798ca8c8cd8952a6588e7958b448c2e 181 Pfam PF00013 KH domain 96 143 5.4E-5 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 STK_05120 4798ca8c8cd8952a6588e7958b448c2e 181 SMART SM00322 75 147 0.0015 T 23-10-2018 IPR004087 K Homology domain GO:0003676 STK_05120 4798ca8c8cd8952a6588e7958b448c2e 181 Gene3D G3DSA:3.30.1370.10 1 73 1.2E-10 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 STK_05120 4798ca8c8cd8952a6588e7958b448c2e 181 Gene3D G3DSA:3.30.1370.10 74 175 3.2E-33 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 STK_05120 4798ca8c8cd8952a6588e7958b448c2e 181 TIGRFAM TIGR03665 arCOG04150: arCOG04150 universal archaeal KH domain protein 2 167 3.0E-62 T 23-10-2018 IPR019964 KH domain protein, archaea STK_05120 4798ca8c8cd8952a6588e7958b448c2e 181 SUPERFAMILY SSF54791 79 158 2.19E-18 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 STK_04990 ec19e0c867bea3da0204844c04faec00 290 Pfam PF02754 Cysteine-rich domain 148 238 3.9E-13 T 23-10-2018 IPR004017 Cysteine-rich domain STK_04990 ec19e0c867bea3da0204844c04faec00 290 Pfam PF02754 Cysteine-rich domain 3 84 2.4E-16 T 23-10-2018 IPR004017 Cysteine-rich domain STK_25180 91fe70f7a547bb7f21360f1d0b9297d0 306 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 16 39 4.4E-5 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal STK_25180 91fe70f7a547bb7f21360f1d0b9297d0 306 Pfam PF01917 Archaebacterial flagellin 20 140 8.3E-18 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 STK_18140 85cb39139154320d7ecc43077f50256e 428 Gene3D G3DSA:1.10.8.60 253 329 1.0E-9 T 23-10-2018 STK_18140 85cb39139154320d7ecc43077f50256e 428 SUPERFAMILY SSF52540 14 326 2.87E-26 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_18140 85cb39139154320d7ecc43077f50256e 428 Gene3D G3DSA:3.40.50.300 6 250 2.6E-22 T 23-10-2018 STK_09780 31d9433a408d6df7862beb9a3d24aa5b 314 Gene3D G3DSA:3.30.70.890 171 303 1.3E-10 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily STK_09780 31d9433a408d6df7862beb9a3d24aa5b 314 SUPERFAMILY SSF55060 172 304 8.15E-18 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily STK_09780 31d9433a408d6df7862beb9a3d24aa5b 314 Gene3D G3DSA:3.30.230.10 1 167 2.9E-28 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup STK_09780 31d9433a408d6df7862beb9a3d24aa5b 314 Pfam PF00288 GHMP kinases N terminal domain 91 149 1.8E-13 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 STK_09780 31d9433a408d6df7862beb9a3d24aa5b 314 SUPERFAMILY SSF54211 2 186 7.36E-39 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold STK_15830 8bb85970b67bb8a4f6c4685bd0dc56e0 237 Pfam PF01061 ABC-2 type transporter 23 205 1.8E-11 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 STK_11930 56548373c6b1dc7e46adce9dbc236c50 240 SUPERFAMILY SSF55681 1 238 3.17E-49 T 23-10-2018 STK_11930 56548373c6b1dc7e46adce9dbc236c50 240 Gene3D G3DSA:3.30.930.10 1 240 2.8E-45 T 23-10-2018 STK_18590 2280ee4ad31b6edf5c681bf96c7460aa 620 Gene3D G3DSA:3.30.70.20 534 615 2.8E-9 T 23-10-2018 STK_18590 2280ee4ad31b6edf5c681bf96c7460aa 620 SUPERFAMILY SSF54862 507 609 1.0E-13 T 23-10-2018 STK_15540 293e4ee4df0b86914b0ccac36472e8b4 334 SUPERFAMILY SSF51306 40 152 3.56E-7 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily STK_23860 617c93de591751ab2cc007b13ecbabf8 352 SUPERFAMILY SSF53756 10 349 4.59E-76 T 23-10-2018 STK_23860 617c93de591751ab2cc007b13ecbabf8 352 Gene3D G3DSA:3.40.50.2000 2 176 1.5E-24 T 23-10-2018 STK_23860 617c93de591751ab2cc007b13ecbabf8 352 Pfam PF13439 Glycosyltransferase Family 4 16 168 4.0E-20 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 STK_23860 617c93de591751ab2cc007b13ecbabf8 352 Pfam PF00534 Glycosyl transferases group 1 174 327 3.0E-33 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 STK_23860 617c93de591751ab2cc007b13ecbabf8 352 Gene3D G3DSA:3.40.50.2000 177 332 3.9E-37 T 23-10-2018 STK_07840 e526d05d4a20a54c92452b56b89a7698 335 SUPERFAMILY SSF103473 7 333 4.19E-21 T 23-10-2018 IPR036259 MFS transporter superfamily STK_07840 e526d05d4a20a54c92452b56b89a7698 335 Gene3D G3DSA:1.20.1250.20 5 172 9.9E-12 T 23-10-2018 STK_07840 e526d05d4a20a54c92452b56b89a7698 335 Gene3D G3DSA:1.20.1250.20 183 334 3.1E-7 T 23-10-2018 STK_09120 8cecc649f3c576a701f95d1406fa6059 254 Pfam PF12773 Double zinc ribbon 4 47 1.6E-10 T 23-10-2018 IPR025874 Double zinc ribbon STK_11210 84e6da2fbb7b1b1ff30269698abba83a 278 SUPERFAMILY SSF56317 2 263 4.97E-69 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily STK_11210 84e6da2fbb7b1b1ff30269698abba83a 278 Pfam PF00795 Carbon-nitrogen hydrolase 3 253 8.3E-54 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 STK_11210 84e6da2fbb7b1b1ff30269698abba83a 278 Gene3D G3DSA:3.60.110.10 1 274 2.4E-83 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily STK_18360 f29847100017ee3c963cab7cf9b0b980 200 Pfam PF13419 Haloacid dehalogenase-like hydrolase 55 153 1.3E-10 T 23-10-2018 STK_18360 f29847100017ee3c963cab7cf9b0b980 200 SUPERFAMILY SSF56784 54 181 1.11E-18 T 23-10-2018 IPR036412 HAD-like superfamily STK_18360 f29847100017ee3c963cab7cf9b0b980 200 Gene3D G3DSA:3.40.50.1000 55 176 1.4E-25 T 23-10-2018 IPR023214 HAD superfamily STK_01660 697d048e8b0b902c6bef2f617a50cfa2 144 Pfam PF04138 GtrA-like protein 7 142 5.0E-22 T 23-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 STK_24450 55793a366dfdff847bb800dad5aa585a 246 Pfam PF01061 ABC-2 type transporter 43 200 1.1E-7 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 STK_03660 aca5e3786c95cf892bc38c6912f07a46 329 SUPERFAMILY SSF51430 5 311 1.31E-57 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily STK_03660 aca5e3786c95cf892bc38c6912f07a46 329 Pfam PF00248 Aldo/keto reductase family 19 308 3.3E-48 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain STK_03660 aca5e3786c95cf892bc38c6912f07a46 329 Gene3D G3DSA:3.20.20.100 4 310 1.3E-56 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily STK_26320 fa28a696c836a541c88c941fb8cd6264 214 Gene3D G3DSA:1.10.10.10 139 209 6.8E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_26320 fa28a696c836a541c88c941fb8cd6264 214 Gene3D G3DSA:3.40.50.11700 1 138 6.0E-49 T 23-10-2018 STK_26320 fa28a696c836a541c88c941fb8cd6264 214 TIGRFAM TIGR01884 cas_HTH: CRISPR locus-related DNA-binding protein 3 201 8.9E-62 T 23-10-2018 IPR010163 CRISPR locus-related putative DNA-binding protein Csa3 STK_18560 3386e7cf18a26e523d311aa534841a81 168 Pfam PF07680 TQO small subunit DoxA 26 156 1.0E-32 T 23-10-2018 IPR011636 Thiosulphate:quinone oxidoreductase small subunit DoxA KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 STK_17490 b2c557831e515723b97a45bfc55dea0a 166 Pfam PF13349 Putative adhesin 45 163 8.7E-9 T 23-10-2018 IPR025164 Putative adhesin STK_15660 b6724632d9c6c883105c76897fab724a 273 Pfam PF06157 Protein of unknown function (DUF973) 14 260 5.7E-22 T 23-10-2018 IPR009321 Protein of unknown function DUF973 STK_22815 7d3a642675eb4da469fcd19b5a243e8c 75 Gene3D G3DSA:3.30.110.40 1 73 1.0E-5 T 23-10-2018 IPR036868 TusA-like domain superfamily STK_22815 7d3a642675eb4da469fcd19b5a243e8c 75 SUPERFAMILY SSF64307 5 73 3.14E-11 T 23-10-2018 IPR036868 TusA-like domain superfamily STK_09960 67b0fb5cadfb00596f9caea6b0d03d11 476 Pfam PF01435 Peptidase family M48 192 291 1.1E-6 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 STK_03720 310240310be16395edabc0ee25143e5f 109 Pfam PF03297 S25 ribosomal protein 14 106 2.4E-18 T 23-10-2018 IPR004977 Ribosomal protein S25 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_03720 310240310be16395edabc0ee25143e5f 109 ProDom PD012268 RIBOSOMAL S25 40S RIBONUCLEOPROTEIN S25 MULTIGENE FAMILY TRANSCRIPTION STRAIN DIRECT 44 108 1.0E-5 T 23-10-2018 IPR004977 Ribosomal protein S25 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 STK_03720 310240310be16395edabc0ee25143e5f 109 Gene3D G3DSA:1.10.10.10 37 109 7.2E-13 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_16050 206a54d347aa628375b314d2320c0038 318 Pfam PF06157 Protein of unknown function (DUF973) 7 317 1.7E-89 T 23-10-2018 IPR009321 Protein of unknown function DUF973 STK_01020 da546144cefe8ed364def58a61f8190f 176 Pfam PF07185 Protein of unknown function (DUF1404) 9 169 4.6E-47 T 23-10-2018 IPR009844 Protein of unknown function DUF1404 STK_19710 5bbb4eecb92de4bbe06e115e527276ef 344 TIGRFAM TIGR01208 rmlA_long: glucose-1-phosphate thymidylyltransferase 3 344 9.9E-128 T 23-10-2018 IPR005908 Glucose-1-phosphate thymidylyltransferase, long form STK_19710 5bbb4eecb92de4bbe06e115e527276ef 344 Gene3D G3DSA:3.90.550.10 1 237 3.1E-69 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_19710 5bbb4eecb92de4bbe06e115e527276ef 344 Gene3D G3DSA:2.160.10.10 238 299 2.0E-9 T 23-10-2018 STK_19710 5bbb4eecb92de4bbe06e115e527276ef 344 SUPERFAMILY SSF53448 1 296 6.76E-72 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_19710 5bbb4eecb92de4bbe06e115e527276ef 344 Pfam PF00483 Nucleotidyl transferase 3 230 1.1E-49 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 STK_16080 a91a90745db9954575b73e7d955a5417 203 Pfam PF03458 UPF0126 domain 7 81 5.0E-19 T 23-10-2018 IPR005115 Uncharacterised domain UPF0126 STK_16080 a91a90745db9954575b73e7d955a5417 203 Pfam PF03458 UPF0126 domain 93 166 1.9E-23 T 23-10-2018 IPR005115 Uncharacterised domain UPF0126 STK_10820 f2334c3905883e17f26831008fee2cf5 244 Gene3D G3DSA:1.10.10.10 48 96 2.6E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_10820 f2334c3905883e17f26831008fee2cf5 244 Pfam PF13384 Homeodomain-like domain 52 90 7.2E-8 T 23-10-2018 STK_10820 f2334c3905883e17f26831008fee2cf5 244 SUPERFAMILY SSF46689 49 132 2.33E-10 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 STK_17410 4653202a860b077725b13e0e619db5ec 130 Gene3D G3DSA:1.10.10.10 10 101 1.4E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_17410 4653202a860b077725b13e0e619db5ec 130 SUPERFAMILY SSF46785 18 100 1.92E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_07945 0a654b58a2872d2f989738934a92c612 114 Gene3D G3DSA:3.30.460.10 16 114 1.4E-14 T 23-10-2018 STK_07945 0a654b58a2872d2f989738934a92c612 114 Pfam PF01909 Nucleotidyltransferase domain 20 74 2.7E-8 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 STK_07945 0a654b58a2872d2f989738934a92c612 114 SUPERFAMILY SSF81301 20 111 3.0E-16 T 23-10-2018 STK_01410 54cda57a87bb9dcc22f55722e5bf04bc 145 Pfam PF06157 Protein of unknown function (DUF973) 47 145 1.9E-16 T 23-10-2018 IPR009321 Protein of unknown function DUF973 STK_11010 8aabb128f91bf283c7a3e1cc7d96eeb1 133 Pfam PF01850 PIN domain 5 125 4.3E-20 T 23-10-2018 IPR002716 PIN domain STK_11010 8aabb128f91bf283c7a3e1cc7d96eeb1 133 Gene3D G3DSA:3.40.50.1010 4 132 3.1E-12 T 23-10-2018 STK_11010 8aabb128f91bf283c7a3e1cc7d96eeb1 133 SUPERFAMILY SSF88723 4 124 1.32E-16 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_06740 fa178299d36f0659b17f3dcf63c6e456 230 Pfam PF12916 Protein of unknown function (DUF3834) 1 202 2.5E-67 T 23-10-2018 IPR024533 Protein of unknown function DUF3834 STK_06740 fa178299d36f0659b17f3dcf63c6e456 230 Gene3D G3DSA:3.40.190.200 1 230 2.2E-85 T 23-10-2018 STK_11700 af857f3df7424e0a52a2a05ddc7feec8 448 Gene3D G3DSA:1.20.1250.20 13 448 6.3E-65 T 23-10-2018 STK_11700 af857f3df7424e0a52a2a05ddc7feec8 448 SUPERFAMILY SSF103473 7 445 1.57E-65 T 23-10-2018 IPR036259 MFS transporter superfamily STK_11700 af857f3df7424e0a52a2a05ddc7feec8 448 Pfam PF00083 Sugar (and other) transporter 23 446 8.4E-37 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 STK_23680 92fa200157169f6a011a6d354e01a4d8 188 Pfam PF12007 Protein of unknown function (DUF3501) 3 182 2.5E-62 T 23-10-2018 IPR021890 Protein of unknown function DUF3501 STK_10890 af7b6e214e0f0f1e189119af05a20c5c 157 Pfam PF05942 Archaeal PaREP1/PaREP8 family 18 143 9.0E-27 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_10450 20cd59460e84a08a180c5703601e31fc 233 Gene3D G3DSA:3.40.50.300 4 214 3.9E-34 T 23-10-2018 STK_10450 20cd59460e84a08a180c5703601e31fc 233 SUPERFAMILY SSF52540 15 199 7.09E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_10450 20cd59460e84a08a180c5703601e31fc 233 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 15 195 1.0E-33 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 STK_07597 845fade4709c21f9863002e2e65f922c 79 Pfam PF01423 LSM domain 12 76 4.4E-24 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type STK_07597 845fade4709c21f9863002e2e65f922c 79 SUPERFAMILY SSF50182 10 78 4.53E-21 T 23-10-2018 IPR010920 LSM domain superfamily STK_07597 845fade4709c21f9863002e2e65f922c 79 Gene3D G3DSA:2.30.30.100 3 78 1.7E-25 T 23-10-2018 STK_07597 845fade4709c21f9863002e2e65f922c 79 SMART SM00651 11 76 3.5E-26 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type STK_19920 e4a242819ac85df0109920375c0d96b6 337 Pfam PF03787 RAMP superfamily 34 277 2.3E-11 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein STK_09810 fe65eed51319edf0bc874868a5e3c978 122 Pfam PF01986 Domain of unknown function DUF123 24 107 5.8E-17 T 23-10-2018 IPR002837 Protein of unknown function DUF123 STK_25400 666f5f752a70a1775de70cd42bd8aa5a 343 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 341 2.5E-37 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 STK_25400 666f5f752a70a1775de70cd42bd8aa5a 343 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 11 34 5.9E-6 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal STK_25400 666f5f752a70a1775de70cd42bd8aa5a 343 SUPERFAMILY SSF161098 97 329 1.03E-11 T 23-10-2018 IPR035906 MetI-like superfamily STK_25400 666f5f752a70a1775de70cd42bd8aa5a 343 Gene3D G3DSA:1.10.3720.10 93 334 2.2E-10 T 23-10-2018 IPR035906 MetI-like superfamily STK_04040 58a97b7fee89cc45e096092203a6ac65 401 Gene3D G3DSA:3.40.50.2000 2 184 1.1E-139 T 23-10-2018 STK_04040 58a97b7fee89cc45e096092203a6ac65 401 Gene3D G3DSA:3.40.50.2000 185 379 1.1E-139 T 23-10-2018 STK_04040 58a97b7fee89cc45e096092203a6ac65 401 Pfam PF00534 Glycosyl transferases group 1 209 372 1.5E-23 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 STK_04040 58a97b7fee89cc45e096092203a6ac65 401 SUPERFAMILY SSF53756 29 388 1.22E-44 T 23-10-2018 STK_02030 f5da638ea89afe2880fbd04aa8746d79 186 Pfam PF09970 Nucleotidyl transferase of unknown function (DUF2204) 13 179 8.3E-55 T 23-10-2018 IPR018700 Protein of unknown function DUF2204 STK_02030 f5da638ea89afe2880fbd04aa8746d79 186 SUPERFAMILY SSF81301 18 144 1.18E-8 T 23-10-2018 STK_21740 8e70e23f5f4c3f3cd622cad3496d54af 323 Gene3D G3DSA:3.20.20.70 21 292 4.6E-38 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_21740 8e70e23f5f4c3f3cd622cad3496d54af 323 SMART SM00729 26 235 2.7E-15 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 STK_21740 8e70e23f5f4c3f3cd622cad3496d54af 323 Pfam PF04055 Radical SAM superfamily 32 198 1.3E-23 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 STK_21740 8e70e23f5f4c3f3cd622cad3496d54af 323 SUPERFAMILY SSF102114 19 253 1.15E-37 T 23-10-2018 STK_21740 8e70e23f5f4c3f3cd622cad3496d54af 323 Pfam PF13394 4Fe-4S single cluster domain 33 119 3.9E-5 T 23-10-2018 STK_05300 f1ab3aa16c15cad9233b90fa3f8f455d 249 Pfam PF00288 GHMP kinases N terminal domain 74 136 3.2E-7 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 STK_05300 f1ab3aa16c15cad9233b90fa3f8f455d 249 SUPERFAMILY SSF54211 4 143 1.75E-10 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold STK_05300 f1ab3aa16c15cad9233b90fa3f8f455d 249 Gene3D G3DSA:3.30.230.10 44 146 3.1E-7 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup STK_05300 f1ab3aa16c15cad9233b90fa3f8f455d 249 PIRSF PIRSF016896 2 236 2.6E-76 T 23-10-2018 IPR012043 Pantoate kinase KEGG: 00770+2.7.1.169|MetaCyc: PWY-6654 STK_19195 264691f544e7d81161632c53c488b79f 76 Pfam PF07362 Post-segregation antitoxin CcdA 7 56 2.1E-6 T 23-10-2018 IPR009956 Post-segregation antitoxin CcdA STK_06380 d90d33ff968f5b3d38c96d0de8c8d707 399 Pfam PF00999 Sodium/hydrogen exchanger family 17 391 7.8E-47 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 STK_06380 d90d33ff968f5b3d38c96d0de8c8d707 399 Gene3D G3DSA:1.20.1530.20 8 397 5.1E-67 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily STK_09980 a62fe0c8bcd955d35d600d0db6196b6d 385 Pfam PF07282 Putative transposase DNA-binding domain 297 361 1.3E-20 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_09980 a62fe0c8bcd955d35d600d0db6196b6d 385 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 243 324 5.3E-26 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_14020 5f02136b413b3d10b11d2c314cb7242a 189 SUPERFAMILY SSF110849 3 189 1.26E-47 T 23-10-2018 IPR036086 ParB/Sulfiredoxin superfamily STK_14020 5f02136b413b3d10b11d2c314cb7242a 189 Pfam PF02195 ParB-like nuclease domain 16 75 2.8E-7 T 23-10-2018 IPR003115 ParB/Sulfiredoxin STK_14020 5f02136b413b3d10b11d2c314cb7242a 189 SMART SM00470 6 87 2.7E-6 T 23-10-2018 IPR003115 ParB/Sulfiredoxin STK_14020 5f02136b413b3d10b11d2c314cb7242a 189 Gene3D G3DSA:3.90.1530.10 1 87 1.8E-20 T 23-10-2018 STK_18510 88e4c822f19fbf9bc5a0f19e9a95d3d4 224 Pfam PF12916 Protein of unknown function (DUF3834) 8 204 2.6E-84 T 23-10-2018 IPR024533 Protein of unknown function DUF3834 STK_18510 88e4c822f19fbf9bc5a0f19e9a95d3d4 224 SUPERFAMILY SSF53850 74 140 9.19E-5 T 23-10-2018 STK_18510 88e4c822f19fbf9bc5a0f19e9a95d3d4 224 Gene3D G3DSA:3.40.190.200 4 206 2.2E-49 T 23-10-2018 STK_21920 89447019f7a68e8ba2b73f66c4e35a0b 398 Pfam PF00534 Glycosyl transferases group 1 208 359 4.7E-24 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 STK_21920 89447019f7a68e8ba2b73f66c4e35a0b 398 SUPERFAMILY SSF53756 12 394 3.66E-34 T 23-10-2018 STK_21920 89447019f7a68e8ba2b73f66c4e35a0b 398 Gene3D G3DSA:3.40.50.2000 197 368 6.9E-29 T 23-10-2018 STK_06240 abfbfce2d978bbf4a167c16ec4ec479e 230 SUPERFAMILY SSF56024 8 64 7.22E-5 T 23-10-2018 STK_16870 65e78670ef28aa78288eb51c5115d84b 144 Pfam PF01850 PIN domain 4 129 5.6E-8 T 23-10-2018 IPR002716 PIN domain STK_16870 65e78670ef28aa78288eb51c5115d84b 144 SUPERFAMILY SSF88723 1 129 1.6E-19 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_16870 65e78670ef28aa78288eb51c5115d84b 144 Gene3D G3DSA:3.40.50.1010 3 140 4.5E-28 T 23-10-2018 STK_25110 a43bd800be4339ba840ec37c8bc1e0e7 259 SUPERFAMILY SSF53474 4 256 4.45E-38 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold STK_25110 a43bd800be4339ba840ec37c8bc1e0e7 259 Pfam PF01738 Dienelactone hydrolase family 16 257 1.2E-71 T 23-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 STK_25500 6e050a989a8622d511b98ee30d3fff39 201 Pfam PF04967 HTH DNA binding domain 144 195 7.4E-23 T 23-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain STK_08900 93a8ca7d6ad6c7bb64d55b89de06c19a 173 Gene3D G3DSA:3.40.50.880 1 173 4.2E-49 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_08900 93a8ca7d6ad6c7bb64d55b89de06c19a 173 SUPERFAMILY SSF52317 1 167 2.81E-46 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like STK_08900 93a8ca7d6ad6c7bb64d55b89de06c19a 173 Pfam PF01965 DJ-1/PfpI family 1 164 1.9E-51 T 23-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 STK_08900 93a8ca7d6ad6c7bb64d55b89de06c19a 173 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 2 167 3.6E-54 T 23-10-2018 IPR006286 Deglycase PfpI STK_26075 1b405d1780d5f14795c13c5c0b880d05 93 Pfam PF02416 mttA/Hcf106 family 12 61 3.1E-9 T 23-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 STK_26075 1b405d1780d5f14795c13c5c0b880d05 93 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 9 50 6.1E-16 T 23-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 STK_08080 4f7e142716783c857c44722a4e02140d 112 Gene3D G3DSA:1.10.10.10 1 112 4.2E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_08080 4f7e142716783c857c44722a4e02140d 112 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 25 61 6.7E-7 T 23-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 STK_08080 4f7e142716783c857c44722a4e02140d 112 SUPERFAMILY SSF46785 1 102 3.9E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_16230 f31f104c5eca423a48f8b0edc89c6209 224 SUPERFAMILY SSF48371 17 221 2.12E-8 T 23-10-2018 IPR016024 Armadillo-type fold STK_04054 a0943c7ce2c08d7eec4af9afedc631e7 84 Pfam PF07935 ORF D-335-like protein 7 73 7.7E-37 T 23-10-2018 IPR012922 ORF D-335-like STK_19550 dbdf76bae3561cf9ed2aa8df6c24a8fc 103 SUPERFAMILY SSF53335 10 94 1.06E-5 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_22000 0c0d45283dca23d4fd9c013ce3047f47 273 SUPERFAMILY SSF159672 55 182 2.22E-18 T 23-10-2018 IPR038029 GbiG N-terminal domain superfamily KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 STK_18770 7d134299239db56cc44dc02f2c25d7a0 126 Gene3D G3DSA:3.40.1260.10 1 126 9.2E-42 T 23-10-2018 IPR027396 DsrEFH-like STK_18770 7d134299239db56cc44dc02f2c25d7a0 126 Pfam PF02635 DsrE/DsrF-like family 8 126 1.6E-22 T 23-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein STK_18770 7d134299239db56cc44dc02f2c25d7a0 126 SUPERFAMILY SSF75169 9 126 2.35E-22 T 23-10-2018 IPR027396 DsrEFH-like STK_06985 62ca77933ee3290243f686ed6291bcb3 76 Pfam PF13463 Winged helix DNA-binding domain 5 68 1.1E-6 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 STK_06985 62ca77933ee3290243f686ed6291bcb3 76 Gene3D G3DSA:1.10.10.10 2 71 7.8E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_06985 62ca77933ee3290243f686ed6291bcb3 76 SUPERFAMILY SSF46785 4 69 8.14E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_15100 5962a9ee9dcbefa4152feec276ef88df 131 SUPERFAMILY SSF49478 65 111 8.63E-6 T 23-10-2018 STK_16430 13739a3554f1730ae07d6d6aa169863f 384 Pfam PF07690 Major Facilitator Superfamily 267 381 3.7E-9 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_16430 13739a3554f1730ae07d6d6aa169863f 384 Pfam PF07690 Major Facilitator Superfamily 21 255 1.5E-16 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_16430 13739a3554f1730ae07d6d6aa169863f 384 SUPERFAMILY SSF103473 1 378 2.09E-38 T 23-10-2018 IPR036259 MFS transporter superfamily STK_16430 13739a3554f1730ae07d6d6aa169863f 384 Gene3D G3DSA:1.20.1250.20 267 381 1.9E-9 T 23-10-2018 STK_16430 13739a3554f1730ae07d6d6aa169863f 384 Gene3D G3DSA:1.20.1250.20 2 266 1.3E-17 T 23-10-2018 STK_08530 8b1d382a185b0499bd238eb98002eb71 288 PIRSF PIRSF018978 2 285 1.7E-37 T 23-10-2018 IPR016742 tRNA methyltransferase, archaea GO:0008175|GO:0030488 STK_05860 5180ff383db18f30f4052dad8724aa68 383 Pfam PF05559 Protein of unknown function (DUF763) 5 338 9.3E-127 T 23-10-2018 IPR008482 Protein of unknown function DUF763 STK_00860 a121f7326c6d1da838e2085fdcb9fd08 144 SUPERFAMILY SSF54637 1 143 7.46E-32 T 23-10-2018 IPR029069 HotDog domain superfamily STK_00860 a121f7326c6d1da838e2085fdcb9fd08 144 Gene3D G3DSA:3.10.129.10 1 142 1.2E-39 T 23-10-2018 STK_00860 a121f7326c6d1da838e2085fdcb9fd08 144 Pfam PF01575 MaoC like domain 7 124 7.2E-20 T 23-10-2018 IPR002539 MaoC-like dehydratase domain STK_11760 b1111325be43b48b7801a88601bf626a 215 Pfam PF02371 Transposase IS116/IS110/IS902 family 94 178 7.3E-27 T 23-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 STK_16340 c5740f0c2987565ef4b314cba048b00b 130 Pfam PF06157 Protein of unknown function (DUF973) 39 129 1.5E-8 T 23-10-2018 IPR009321 Protein of unknown function DUF973 STK_09100 45c11ad4f1ad4e4c8b8a2b21d115f74f 126 Pfam PF05942 Archaeal PaREP1/PaREP8 family 6 111 3.1E-24 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_09100 45c11ad4f1ad4e4c8b8a2b21d115f74f 126 Gene3D G3DSA:1.20.120.330 2 123 7.2E-34 T 23-10-2018 STK_23250 a1bdb7b406a329b7820433e1aa50667d 277 Pfam PF07282 Putative transposase DNA-binding domain 209 271 4.3E-21 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_00350 7cddcbd20b1d39f8ef95bf490b20765a 430 SUPERFAMILY SSF88723 252 351 4.45E-5 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_09590 821f9bf3faf8fe5936f0bc3e3d7d3a3f 278 Gene3D G3DSA:1.10.443.10 110 274 2.0E-27 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 STK_09590 821f9bf3faf8fe5936f0bc3e3d7d3a3f 278 SUPERFAMILY SSF56349 24 227 2.35E-9 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 STK_09590 821f9bf3faf8fe5936f0bc3e3d7d3a3f 278 Pfam PF16795 Archaeal phage integrase 114 269 4.8E-27 T 23-10-2018 IPR031857 Integrase SSV1, C-terminal STK_04920 ddfc4019394284833584c6d65530291d 179 Gene3D G3DSA:3.60.21.10 2 177 1.1E-6 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like STK_04920 ddfc4019394284833584c6d65530291d 179 SUPERFAMILY SSF56300 1 168 5.48E-11 T 23-10-2018 STK_16490 ea27a47ef5625dcf845943340e609b10 409 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 231 408 4.6E-12 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 STK_15910 b01eebf44629b53a91ab8aa73669907e 484 Gene3D G3DSA:3.30.70.20 397 470 2.9E-10 T 23-10-2018 STK_15910 b01eebf44629b53a91ab8aa73669907e 484 Pfam PF13237 4Fe-4S dicluster domain 403 454 2.6E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_15910 b01eebf44629b53a91ab8aa73669907e 484 SUPERFAMILY SSF54862 377 460 1.09E-13 T 23-10-2018 STK_11630 b8eae8770f1ad49b6fc591ce24155d8e 113 Pfam PF05168 HEPN domain 10 107 3.2E-8 T 23-10-2018 IPR007842 HEPN domain STK_11630 b8eae8770f1ad49b6fc591ce24155d8e 113 Gene3D G3DSA:1.20.120.330 2 112 1.0E-10 T 23-10-2018 STK_07740 8d6b3409098414ee5275c3c1c6f2c422 131 SUPERFAMILY SSF55961 14 126 5.89E-7 T 23-10-2018 STK_11890 a9488a39289249091af7ffc431bcb692 475 SUPERFAMILY SSF52540 16 382 5.69E-7 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_11890 a9488a39289249091af7ffc431bcb692 475 Pfam PF13175 AAA ATPase domain 3 380 1.9E-10 T 23-10-2018 STK_26150 fd324b81623fd225ef7a32c899feaf5d 1062 Pfam PF05317 Thermopsin 47 310 1.2E-82 T 23-10-2018 IPR007981 Peptidase A5, thermopsin STK_08960 079763b2571f26bdb9c479c06c2f6ab2 175 Pfam PF05942 Archaeal PaREP1/PaREP8 family 27 145 1.0E-27 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_22140 ecf0be97c5aeb0d4a61de0ddc0d5edba 112 Pfam PF09943 Uncharacterized protein conserved in archaea (DUF2175) 6 106 7.4E-36 T 23-10-2018 IPR018686 Protein of unknown function DUF2175 STK_22650 3f971a547f4a7cb0325290bd66f23f18 340 PIRSF PIRSF032968 1 340 2.8E-200 T 23-10-2018 IPR017013 Archaeal Cdc45 STK_22070 f2fd7305e33dd62c76fc883e8e486750 432 Pfam PF05317 Thermopsin 32 248 1.7E-24 T 23-10-2018 IPR007981 Peptidase A5, thermopsin STK_02660 efc23f193f2debf6b3c94560eae2504f 147 SUPERFAMILY SSF55729 23 113 4.75E-20 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase STK_02660 efc23f193f2debf6b3c94560eae2504f 147 Pfam PF00583 Acetyltransferase (GNAT) family 27 105 3.5E-14 T 23-10-2018 IPR000182 GNAT domain STK_02660 efc23f193f2debf6b3c94560eae2504f 147 Gene3D G3DSA:3.40.630.30 1 122 2.2E-21 T 23-10-2018 STK_22660 aa14f4ea507698f53fe44b4679141361 302 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 19 260 9.0E-12 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD STK_15380 a8e88a36fe37ad1049eae1c391978b4e 202 Pfam PF06168 Protein of unknown function (DUF981) 1 192 1.0E-56 T 23-10-2018 IPR009324 Protein of unknown function DUF981 STK_18850 0f3a9f85bbe2fe51d5fc4313bfcf793f 272 Gene3D G3DSA:2.70.70.10 10 123 7.8E-12 T 23-10-2018 IPR011055 Duplicated hybrid motif STK_21630 7c3dc866d10d06fbca51d92dbfcc3e69 270 Pfam PF05552 Conserved TM helix 11 53 3.0E-9 T 23-10-2018 IPR008910 Conserved TM helix STK_12850 584315393133fae73df8eff47e216a69 111 SUPERFAMILY SSF54913 3 104 1.71E-35 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta STK_12850 584315393133fae73df8eff47e216a69 111 Gene3D G3DSA:3.30.70.120 1 106 1.2E-36 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal STK_12850 584315393133fae73df8eff47e216a69 111 Pfam PF03091 CutA1 divalent ion tolerance protein 5 101 4.5E-34 T 23-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 STK_19510 c13c0f97bb03e17bb5445c7e368f2aef 469 Pfam PF01943 Polysaccharide biosynthesis protein 5 261 1.3E-6 T 23-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 STK_23790 8a7ab6a69e123f8df4ce2ddc58c8e205 307 SUPERFAMILY SSF53448 3 232 1.5E-21 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_23790 8a7ab6a69e123f8df4ce2ddc58c8e205 307 Gene3D G3DSA:3.90.550.10 4 237 3.2E-24 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases STK_23790 8a7ab6a69e123f8df4ce2ddc58c8e205 307 Pfam PF00535 Glycosyl transferase family 2 6 130 2.3E-11 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 STK_12930 4830f4cb9585f7f17842066ceddc63e8 311 Hamap MF_00153 Probable deoxyhypusine synthase [dys]. 22 310 42.756 T 23-10-2018 IPR022899 Deoxyhypusine synthase, putative, archaeal GO:0034038 STK_12930 4830f4cb9585f7f17842066ceddc63e8 311 SUPERFAMILY SSF52467 3 310 2.45E-99 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily STK_12930 4830f4cb9585f7f17842066ceddc63e8 311 Gene3D G3DSA:3.40.910.10 1 311 1.2E-93 T 23-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 STK_12930 4830f4cb9585f7f17842066ceddc63e8 311 Pfam PF01916 Deoxyhypusine synthase 32 307 1.4E-101 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 STK_18680 d902c4547808e759d42d30818c4bfbc3 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.2E-42 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_18680 d902c4547808e759d42d30818c4bfbc3 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.2E-42 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_18680 d902c4547808e759d42d30818c4bfbc3 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.2E-42 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_18680 d902c4547808e759d42d30818c4bfbc3 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.2E-42 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_18680 d902c4547808e759d42d30818c4bfbc3 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.2E-42 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_18680 d902c4547808e759d42d30818c4bfbc3 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.2E-42 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_18680 d902c4547808e759d42d30818c4bfbc3 258 SUPERFAMILY SSF51735 12 250 1.63E-79 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily STK_18680 d902c4547808e759d42d30818c4bfbc3 258 Gene3D G3DSA:3.40.50.720 10 256 5.4E-79 T 23-10-2018 STK_18680 d902c4547808e759d42d30818c4bfbc3 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.3E-9 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_18680 d902c4547808e759d42d30818c4bfbc3 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.3E-9 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_18680 d902c4547808e759d42d30818c4bfbc3 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.3E-9 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR STK_18680 d902c4547808e759d42d30818c4bfbc3 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 249 7.1E-64 T 23-10-2018 STK_18130 c417e87605bda3635c02f52b2cd68640 264 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 261 14.765 T 23-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 STK_18130 c417e87605bda3635c02f52b2cd68640 264 Pfam PF02673 Bacitracin resistance protein BacA 7 245 1.5E-46 T 23-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 STK_20420 d1a38a8130a2d9fedf83c233723f5e11 230 SUPERFAMILY SSF53335 45 218 3.99E-25 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase STK_20420 d1a38a8130a2d9fedf83c233723f5e11 230 Pfam PF08241 Methyltransferase domain 87 175 2.4E-16 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 STK_20420 d1a38a8130a2d9fedf83c233723f5e11 230 Gene3D G3DSA:3.40.50.150 34 225 1.1E-24 T 23-10-2018 STK_07590 5860eaae3472564ce29df667c4cd244c 510 Pfam PF00474 Sodium:solute symporter family 41 437 9.3E-11 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 STK_07590 5860eaae3472564ce29df667c4cd244c 510 Gene3D G3DSA:1.20.1730.10 31 508 2.9E-26 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily STK_16930 9bf6799be0e65bfd61a0ad4492879e53 314 SUPERFAMILY SSF56091 70 232 3.2E-6 T 23-10-2018 STK_26420 d703bd670eb0317a8bd082919bbc68e1 269 Gene3D G3DSA:3.30.70.1900 108 269 7.5E-54 T 23-10-2018 STK_26420 d703bd670eb0317a8bd082919bbc68e1 269 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 122 263 5.1E-13 T 23-10-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal STK_26420 d703bd670eb0317a8bd082919bbc68e1 269 Gene3D G3DSA:3.30.70.2990 1 107 7.2E-43 T 23-10-2018 STK_09140 9a1468ea5765bd27fd606ab1c8ebb045 452 SUPERFAMILY SSF52540 29 244 3.92E-11 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_09140 9a1468ea5765bd27fd606ab1c8ebb045 452 Gene3D G3DSA:3.40.50.300 25 199 1.3E-6 T 23-10-2018 STK_13890 781723b45c353eccb7bc101995d92e94 293 PIRSF PIRSF004884 1 291 2.5E-102 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 STK_13890 781723b45c353eccb7bc101995d92e94 293 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 62 265 6.1E-62 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 STK_06670 26f8ea6e52cde75ec6b631558547e19f 210 Gene3D G3DSA:3.40.50.11330 90 209 3.3E-25 T 23-10-2018 STK_06670 26f8ea6e52cde75ec6b631558547e19f 210 Gene3D G3DSA:3.40.50.1860 1 86 7.7E-6 T 23-10-2018 STK_02670 b2c23c3f72b7a6d4ae3e44c86e57d11a 176 Pfam PF01955 Adenosylcobinamide amidohydrolase 11 169 6.1E-21 T 23-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ STK_16470 962acc9697879c6cf1981c45d66a6eff 279 Gene3D G3DSA:3.40.50.300 8 276 4.7E-31 T 23-10-2018 STK_16470 962acc9697879c6cf1981c45d66a6eff 279 SUPERFAMILY SSF52540 17 229 1.78E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_16470 962acc9697879c6cf1981c45d66a6eff 279 Pfam PF00005 ABC transporter 16 157 5.8E-7 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 STK_10790 02a38e002e76d5b9b69807195e5559ed 170 SUPERFAMILY SSF88723 4 117 1.18E-5 T 23-10-2018 IPR029060 PIN-like domain superfamily STK_00300 798a354b2fd5bad3bdd791c2dd074ff0 260 Gene3D G3DSA:3.30.70.3120 5 252 1.2E-47 T 23-10-2018 STK_00300 798a354b2fd5bad3bdd791c2dd074ff0 260 TIGRFAM TIGR01874 cas_cas5a: CRISPR-associated protein Cas5, subtype I-A/APERN 10 176 6.6E-14 T 23-10-2018 IPR010153 CRISPR-associated protein, Cas5a type STK_00374 aa159afb73cfb218fed4aa2067435c6d 56 SUPERFAMILY SSF81593 5 44 3.06E-7 T 23-10-2018 STK_00130 0a9bd8423c0503f763c0b7cc9269e1e9 203 PIRSF PIRSF032748 1 203 2.4E-125 T 23-10-2018 IPR017005 Uncharacterised conserved protein UCP032748 STK_00130 0a9bd8423c0503f763c0b7cc9269e1e9 203 Pfam PF03787 RAMP superfamily 7 172 4.7E-10 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein STK_23360 e71ac547a781a42467e3e3050d0a8fe5 104 Gene3D G3DSA:1.10.10.10 1 103 3.5E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_23360 e71ac547a781a42467e3e3050d0a8fe5 104 Pfam PF13412 Winged helix-turn-helix DNA-binding 8 50 2.1E-5 T 23-10-2018 STK_23360 e71ac547a781a42467e3e3050d0a8fe5 104 SUPERFAMILY SSF46785 1 83 2.36E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_23360 e71ac547a781a42467e3e3050d0a8fe5 104 PIRSF PIRSF032840 1 104 4.9E-56 T 23-10-2018 IPR017009 Uncharacterised conserved protein UCP032840 STK_04930 21c5954c820da4491fc215493855746d 126 Gene3D G3DSA:3.40.50.11100 1 126 2.8E-60 T 23-10-2018 STK_02504 da811675cfc5477ebcaf4ad35ae2a6ee 86 SUPERFAMILY SSF46785 11 83 2.36E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_02504 da811675cfc5477ebcaf4ad35ae2a6ee 86 Pfam PF14947 Winged helix-turn-helix 10 75 7.3E-10 T 23-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain STK_02504 da811675cfc5477ebcaf4ad35ae2a6ee 86 Gene3D G3DSA:1.10.10.10 8 84 8.8E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_05580 4f39b1ec03fa48c3ba42a709f8802ee2 132 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 12 131 1.3E-7 T 23-10-2018 IPR010419 Carbon monoxide dehydrogenase subunit G STK_18530 a3b069ae88f5b7a109938f8fd59e693f 364 Gene3D G3DSA:1.20.1250.20 2 183 1.6E-20 T 23-10-2018 STK_18530 a3b069ae88f5b7a109938f8fd59e693f 364 Gene3D G3DSA:1.20.1250.20 191 362 2.6E-15 T 23-10-2018 STK_18530 a3b069ae88f5b7a109938f8fd59e693f 364 Pfam PF07690 Major Facilitator Superfamily 17 176 4.7E-19 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_18530 a3b069ae88f5b7a109938f8fd59e693f 364 Pfam PF07690 Major Facilitator Superfamily 203 353 4.8E-12 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 STK_18530 a3b069ae88f5b7a109938f8fd59e693f 364 SUPERFAMILY SSF103473 4 356 3.66E-42 T 23-10-2018 IPR036259 MFS transporter superfamily STK_11950 d7e0ec6660211091beb6838c45160fee 243 SUPERFAMILY SSF102114 4 208 6.02E-14 T 23-10-2018 STK_11950 d7e0ec6660211091beb6838c45160fee 243 Gene3D G3DSA:3.20.20.70 2 208 1.1E-8 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 STK_11540 026f4fdd5e07beabd933b4ca0b2f3747 152 Pfam PF03400 IS1 transposase 22 137 8.1E-5 T 23-10-2018 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 STK_19990 62236245e3064dbffb5ac507c47a9b25 158 Pfam PF04693 Archaeal putative transposase ISC1217 86 131 1.1E-16 T 23-10-2018 IPR006783 Transposase, ISC1217 STK_19990 62236245e3064dbffb5ac507c47a9b25 158 Pfam PF04693 Archaeal putative transposase ISC1217 1 33 3.0E-10 T 23-10-2018 IPR006783 Transposase, ISC1217 STK_02410 cfb52ac5f65e1ec8cf879c194cee33a1 132 Pfam PF03966 Trm112p-like protein 2 88 9.2E-21 T 23-10-2018 IPR005651 Trm112-like STK_02410 cfb52ac5f65e1ec8cf879c194cee33a1 132 SUPERFAMILY SSF158997 3 103 5.23E-13 T 23-10-2018 STK_23725 5c70c5228289eb4cffa771af356eff39 112 Pfam PF07843 Protein of unknown function (DUF1634) 7 104 1.7E-18 T 23-10-2018 IPR012861 Protein of unknown function DUF1634 STK_09230 6aaba769ba938520195e53ca8aff08c5 124 PIRSF PIRSF014405 1 124 1.4E-59 T 23-10-2018 IPR012372 Uncharacterised conserved protein UCP014405, metallopeptidase Zn-binding site STK_08500 7820fe7aa40e86681045446693d47d4d 444 SUPERFAMILY SSF52540 15 328 1.64E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_08500 7820fe7aa40e86681045446693d47d4d 444 SMART SM00382 39 231 0.0026 T 23-10-2018 IPR003593 AAA+ ATPase domain STK_21140 1b74c5874e47cf9eeb23da335becf175 141 Pfam PF01475 Ferric uptake regulator family 12 122 2.4E-24 T 23-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 STK_21140 1b74c5874e47cf9eeb23da335becf175 141 SUPERFAMILY SSF46785 5 130 2.98E-28 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily STK_21140 1b74c5874e47cf9eeb23da335becf175 141 Gene3D G3DSA:1.10.10.10 3 81 1.6E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_17265 e09a7b8c88c7cd1113546165c176c60c 75 Pfam PF02697 Putative antitoxin 7 74 1.2E-15 T 23-10-2018 IPR003847 Putative antitoxin STK_15977 8c75df8de1766d2407995388f444bd37 85 Pfam PF14210 Domain of unknown function (DUF4322) 2 53 5.0E-11 T 23-10-2018 IPR025471 Domain of unknown function DUF4322 STK_05220 15d08e938f5bf231e0d349138e327249 575 Gene3D G3DSA:3.30.450.380 57 281 3.7E-45 T 23-10-2018 STK_05220 15d08e938f5bf231e0d349138e327249 575 SUPERFAMILY SSF52540 159 477 7.83E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_05220 15d08e938f5bf231e0d349138e327249 575 Gene3D G3DSA:3.40.50.300 283 567 1.9E-77 T 23-10-2018 STK_05220 15d08e938f5bf231e0d349138e327249 575 Pfam PF00437 Type II/IV secretion system protein 223 431 3.0E-45 T 23-10-2018 IPR001482 Type II/IV secretion system protein STK_01640 1c61c7826ca2cd18c7f18d9ab07d0b9c 192 Pfam PF04967 HTH DNA binding domain 132 184 1.8E-20 T 23-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain STK_24690 6c032e3ead10bf49616be118cca5d2e7 412 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 238 322 8.4E-21 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_24690 6c032e3ead10bf49616be118cca5d2e7 412 Pfam PF07282 Putative transposase DNA-binding domain 295 367 4.2E-18 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal STK_25600 42f1da638497f0291887246b085c2c64 387 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 5 384 8.2E-122 T 23-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 STK_25890 32e0aea1fabefcb4e979701b3fbba96a 201 Pfam PF07185 Protein of unknown function (DUF1404) 10 197 7.8E-52 T 23-10-2018 IPR009844 Protein of unknown function DUF1404 STK_00110 bd4951cd949a6abef3b6e716df7d7ee6 264 Pfam PF03787 RAMP superfamily 24 177 1.3E-10 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein STK_21220 4e60d7151732489fbe6d07554269d01f 302 Pfam PF01266 FAD dependent oxidoreductase 85 294 4.1E-11 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 STK_21220 4e60d7151732489fbe6d07554269d01f 302 Gene3D G3DSA:3.30.9.10 74 261 1.8E-12 T 23-10-2018 STK_21220 4e60d7151732489fbe6d07554269d01f 302 Gene3D G3DSA:3.50.50.60 115 299 1.8E-12 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_21220 4e60d7151732489fbe6d07554269d01f 302 SUPERFAMILY SSF51905 1 208 7.4E-9 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily STK_20570 17f33ba2fb3293e171f646dc944a2e35 328 Pfam PF00953 Glycosyl transferase family 4 83 240 5.5E-32 T 23-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 STK_26160 305a8450483aaef6009b5104185f658e 203 Pfam PF06157 Protein of unknown function (DUF973) 7 199 6.8E-7 T 23-10-2018 IPR009321 Protein of unknown function DUF973 STK_15890 9a0a76f48c6d2278901c49bd373df711 263 Pfam PF06053 Domain of unknown function (DUF929) 7 231 4.8E-62 T 23-10-2018 IPR009272 Protein of unknown function DUF929 STK_15890 9a0a76f48c6d2278901c49bd373df711 263 SUPERFAMILY SSF52833 75 179 2.74E-6 T 23-10-2018 IPR036249 Thioredoxin-like superfamily STK_16570 d797c96ab0a6e1ce214a1489843866f6 381 Pfam PF06157 Protein of unknown function (DUF973) 4 363 2.7E-25 T 23-10-2018 IPR009321 Protein of unknown function DUF973 STK_07690 6e68f01cdaf8cde5d2b1c9d693e6a793 257 Gene3D G3DSA:3.40.50.300 2 256 7.7E-22 T 23-10-2018 STK_07690 6e68f01cdaf8cde5d2b1c9d693e6a793 257 SUPERFAMILY SSF52540 1 221 6.12E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase STK_07690 6e68f01cdaf8cde5d2b1c9d693e6a793 257 Pfam PF13614 AAA domain 3 125 1.2E-17 T 23-10-2018 IPR025669 AAA domain STK_13300 d1b0dafcd0c76d764eb15319c856b63b 348 SUPERFAMILY SSF56024 73 152 2.79E-10 T 23-10-2018 STK_13300 d1b0dafcd0c76d764eb15319c856b63b 348 Gene3D G3DSA:3.30.870.10 12 173 6.4E-28 T 23-10-2018 STK_13300 d1b0dafcd0c76d764eb15319c856b63b 348 Pfam PF13091 PLD-like domain 22 146 1.9E-14 T 23-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 STK_17500 5864d861c8e730fad238c2f62f44b36d 127 Pfam PF13349 Putative adhesin 5 94 4.1E-7 T 23-10-2018 IPR025164 Putative adhesin STK_08540 75fadb5e2f313f2b7655dbcf5374e42b 386 Pfam PF02371 Transposase IS116/IS110/IS902 family 240 321 6.4E-23 T 23-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 STK_08540 75fadb5e2f313f2b7655dbcf5374e42b 386 Pfam PF01548 Transposase 12 158 2.4E-17 T 23-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 STK_05890 1f6ca9f7a30d9118ae74758167f59f2f 321 Pfam PF01384 Phosphate transporter family 19 308 1.2E-20 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 STK_19780 8a757ccc6db747ac362ce715a837eb55 288 TIGRFAM TIGR01898 cas_TM1791_cmr6: CRISPR type III-B/RAMP module RAMP protein Cmr6 170 277 3.1E-28 T 23-10-2018 IPR010172 CRISPR-associated protein, TM1791 STK_19780 8a757ccc6db747ac362ce715a837eb55 288 Pfam PF03787 RAMP superfamily 143 275 5.4E-10 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein STK_10710 7f0d93c127874a52e563597d99019455 464 SUPERFAMILY SSF117289 70 149 4.71E-5 T 23-10-2018 STK_17164 72928ebb1ec14b9928616f6f0ba9cb3a 68 Pfam PF07935 ORF D-335-like protein 7 67 3.9E-26 T 23-10-2018 IPR012922 ORF D-335-like STK_19570 8b00c0ac883bfd2b1537327ddaf7a7b1 354 Pfam PF01609 Transposase DDE domain 153 303 4.9E-11 T 23-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 STK_23200 7e563c7e244bb6b32a3f3c29c5edd381 160 Pfam PF09821 C-terminal AAA-associated domain 35 149 3.4E-28 T 23-10-2018 IPR018632 C-terminal AAA-associated domain STK_14060 a64a0cdc15cd99c7e1eebf629887fe26 227 Pfam PF09958 Uncharacterized protein conserved in archaea (DUF2192) 3 226 9.7E-84 T 23-10-2018 IPR018693 Protein of unknown function DUF2192 STK_07470 894f452b9e901b15dfbf23d1396dc6c3 261 Pfam PF06053 Domain of unknown function (DUF929) 4 258 1.6E-76 T 23-10-2018 IPR009272 Protein of unknown function DUF929 STK_17465 f26755c1245384873cc853577db1b7e0 115 Pfam PF05942 Archaeal PaREP1/PaREP8 family 8 112 4.4E-27 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_17465 f26755c1245384873cc853577db1b7e0 115 Gene3D G3DSA:1.20.120.330 5 115 9.7E-38 T 23-10-2018 STK_03150 b9577512061ff1e7d5747406125d9562 275 Gene3D G3DSA:1.10.10.10 2 71 3.4E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily STK_03130 087e9225acb64a5c5b92cd29bd9900d5 432 SUPERFAMILY SSF56349 130 416 1.71E-25 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 STK_03130 087e9225acb64a5c5b92cd29bd9900d5 432 Pfam PF00589 Phage integrase family 229 390 6.0E-15 T 23-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 STK_20115 f5966e0aa2379c1f56dd6a5e30adef8c 70 ProDom PD052018 AF1456 COIL COILED 19 70 2.0E-4 T 23-10-2018 STK_10360 2ed8ad7376de9970a8ed0682e35b71a9 312 Pfam PF06157 Protein of unknown function (DUF973) 6 311 2.4E-92 T 23-10-2018 IPR009321 Protein of unknown function DUF973 STK_03425 91b553e2d3483d554d749401793481b0 90 Pfam PF07935 ORF D-335-like protein 7 74 3.9E-31 T 23-10-2018 IPR012922 ORF D-335-like STK_17330 adb99b8bfe8d023977ef5e109d047bc4 269 Pfam PF06053 Domain of unknown function (DUF929) 9 258 2.5E-81 T 23-10-2018 IPR009272 Protein of unknown function DUF929 STK_22405 e0510c1d5a6292cfe583327dc2ff8d50 94 Pfam PF01998 Protein of unknown function DUF131 25 87 1.7E-22 T 23-10-2018 IPR002849 Protein of unknown function DUF131 STK_22880 75f6778159c0f56afd7adf3646b3aa02 144 SUPERFAMILY SSF54585 88 142 4.9E-5 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily STK_07310 e4e4dce4fb72d3c1f531281de2ec0942 100 Pfam PF01184 GPR1/FUN34/yaaH family 6 92 3.6E-17 T 23-10-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 STK_26350 07219d27d6054d56bbf4fb7ea0c60008 176 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 3 171 1.0E-49 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 STK_26350 07219d27d6054d56bbf4fb7ea0c60008 176 Pfam PF01930 Domain of unknown function DUF83 3 170 5.5E-20 T 23-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 STK_26350 07219d27d6054d56bbf4fb7ea0c60008 176 Gene3D G3DSA:3.90.320.10 1 173 4.0E-16 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal STK_05035 705d0fb5db8a8f31134b7df0bcf95cbb 93 Gene3D G3DSA:1.10.10.1150 21 93 8.5E-7 T 23-10-2018 STK_05035 705d0fb5db8a8f31134b7df0bcf95cbb 93 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 31 91 1.2E-13 T 23-10-2018 IPR008792 Coenzyme PQQ synthesis D STK_17690 2615843f01d1f9211a92eb5e4944cb5e 350 Pfam PF01609 Transposase DDE domain 149 290 1.1E-8 T 23-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 STK_20060 fd7e7401b034e6bab7cb68dfb778baba 289 Pfam PF12686 Protein of unknown function (DUF3800) 4 273 9.1E-35 T 23-10-2018 IPR024524 Protein of unknown function DUF3800 STK_13990 031e83011fe9a4ec716be65d489551a4 155 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 9 30 3.6E-6 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal STK_24080 5b610d15c5e2c7e54ce70ace189542ed 195 Pfam PF03692 Putative zinc- or iron-chelating domain 59 137 4.1E-10 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein STK_24140 621ed252782829d7a9c26005f9b928d4 340 Gene3D G3DSA:1.10.620.20 19 251 4.7E-16 T 23-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 STK_24140 621ed252782829d7a9c26005f9b928d4 340 SUPERFAMILY SSF47240 4 249 3.14E-38 T 23-10-2018 IPR009078 Ferritin-like superfamily STK_23970 53ccf09eb9b7c9923aa24589312e9d1e 186 Pfam PF07185 Protein of unknown function (DUF1404) 15 182 1.0E-60 T 23-10-2018 IPR009844 Protein of unknown function DUF1404 STK_01380 907d3f23c637e8f87ba05a8003c77ffd 185 Pfam PF07185 Protein of unknown function (DUF1404) 14 182 3.1E-59 T 23-10-2018 IPR009844 Protein of unknown function DUF1404 STK_21040 5445ed205d55faf0fc80a00ff4bbc94d 141 SUPERFAMILY SSF47240 1 127 1.04E-12 T 23-10-2018 IPR009078 Ferritin-like superfamily STK_07220 41967b7c6794635dc7b0155588826cf9 206 Pfam PF04967 HTH DNA binding domain 147 199 9.4E-21 T 23-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain STK_16760 0f30b1803075b5f69eff2ebad8d6c8a8 197 Pfam PF13240 zinc-ribbon domain 3 25 4.1E-8 T 23-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 STK_19490 f523b5918977cf27f6e9f22e0e01bf89 135 Pfam PF04693 Archaeal putative transposase ISC1217 1 107 5.2E-54 T 23-10-2018 IPR006783 Transposase, ISC1217 STK_18700 5e7cac505de3721c763ebbc19da567a0 307 Pfam PF02754 Cysteine-rich domain 158 247 1.6E-9 T 23-10-2018 IPR004017 Cysteine-rich domain STK_18700 5e7cac505de3721c763ebbc19da567a0 307 Pfam PF02754 Cysteine-rich domain 12 94 1.1E-16 T 23-10-2018 IPR004017 Cysteine-rich domain STK_18570 a7fe59465c372b4e2a8e6b99c9fa3b9c 464 Gene3D G3DSA:1.25.40.10 109 319 4.2E-6 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 STK_02480 4979d62eb66af4df8055b4a0d9940b9c 149 Pfam PF04693 Archaeal putative transposase ISC1217 1 87 5.0E-35 T 23-10-2018 IPR006783 Transposase, ISC1217 STK_25440 82466e030036d11f248cde8854f612a1 129 Pfam PF03703 Bacterial PH domain 53 123 1.1E-5 T 23-10-2018 IPR005182 Domain of unknown function DUF304 STK_03060 7d9c71dd1f4e5dfe241991ff78d4164a 102 Pfam PF07935 ORF D-335-like protein 14 79 5.2E-33 T 23-10-2018 IPR012922 ORF D-335-like STK_12720 1d721ca5eec5c112607462ced519a41b 100 SUPERFAMILY SSF50447 15 79 6.36E-9 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily STK_12720 1d721ca5eec5c112607462ced519a41b 100 Gene3D G3DSA:2.40.10.230 8 90 2.0E-11 T 23-10-2018 IPR038664 H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain STK_19800 b9823152e5d443be5fb6f9cab04f0925 299 Pfam PF09700 CRISPR-associated protein (Cas_Cmr3) 7 87 3.3E-8 T 23-10-2018 IPR019117 CRISPR-associated protein, Cmr3 STK_19800 b9823152e5d443be5fb6f9cab04f0925 299 Pfam PF09700 CRISPR-associated protein (Cas_Cmr3) 141 224 5.5E-7 T 23-10-2018 IPR019117 CRISPR-associated protein, Cmr3 STK_19800 b9823152e5d443be5fb6f9cab04f0925 299 TIGRFAM TIGR01888 cas_cmr3: CRISPR type III-B/RAMP module-associated protein Cmr3 7 297 1.6E-67 T 23-10-2018 IPR010165 CRISPR-associated protein, TM1793 STK_22590 e1ec622151db9e1d225742cbd0ba6756 233 Pfam PF13610 DDE domain 78 187 2.0E-6 T 23-10-2018 IPR032874 DDE domain STK_25980 4bf8a884acd7312e8e2aea02642c0786 393 Pfam PF12801 4Fe-4S binding domain 158 196 6.5E-5 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_25980 4bf8a884acd7312e8e2aea02642c0786 393 Pfam PF12801 4Fe-4S binding domain 249 276 0.67 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain STK_15600 3cd4e69461b06328ff8cb953d410060c 162 Pfam PF05942 Archaeal PaREP1/PaREP8 family 17 143 9.9E-25 T 23-10-2018 IPR010268 Archaeal PaREP1 STK_14000 cc10e3e88e2191560cbc47a06add279b 131 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 1 24 7.3E-7 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal STK_00150 0d163eaad72a218f1b4e7a62b33446ea 231 Pfam PF03787 RAMP superfamily 26 201 2.4E-14 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein STK_09685 5f5db665ba42955d10a93deb55d92dc8 52 Pfam PF06281 Protein of unknown function (DUF1035) 1 51 1.6E-15 T 23-10-2018 IPR009379 VP1/VP3 GO:0005198|GO:0016021 STK_09565 c20951ee387dad8bc47a0225f7a7f3a7 60 Gene3D G3DSA:2.10.260.10 1 60 1.4E-28 T 23-10-2018 STK_11350 3be5fc8342831fcfbcf3175ff8b373fe 301 Pfam PF02361 Cobalt transport protein 42 260 1.0E-14 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component STK_04790 98211de33d0a40ca0859aff5de2d98c3 143 PIRSF PIRSF014422 1 143 2.1E-69 T 23-10-2018 IPR016618 Uncharacterised conserved protein UCP014422 STK_01390 f90b342f6d75db9c2113eebe9cf21d02 146 Pfam PF04982 HPP family 31 139 5.5E-9 T 23-10-2018 IPR007065 HPP STK_25920 36d2993c6f461e5d5cf6688b19e36420 142 Gene3D G3DSA:2.60.40.1190 5 61 2.0E-5 T 23-10-2018 STK_17560 0cf5d6e84f029bba378dbc1e82856adf 174 Pfam PF05942 Archaeal PaREP1/PaREP8 family 15 136 1.2E-26 T 23-10-2018 IPR010268 Archaeal PaREP1