locus-tag	class	description
Sulba_0002	COG0592	DNA-directed DNA polymerase activity
Sulba_0003	COG0187	DNA topoisomerase II activity
Sulba_0005	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Sulba_0008	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Sulba_0009	COG1194	a g-specific adenine glycosylase
Sulba_0010	COG4175	Glycine betaine
Sulba_0011	COG4176	ABC-type proline glycine betaine transport system permease component
Sulba_0012	COG2113	Glycine betaine
Sulba_0014	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Sulba_0015	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
Sulba_0016	COG1802	Transcriptional regulator
Sulba_0020	COG0840	transmembrane signaling receptor activity
Sulba_0024	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Sulba_0025	COG1335	isochorismatase
Sulba_0029	COG3708	Transcriptional regulator
Sulba_0029	COG2207	Transcriptional regulator
Sulba_0034	COG0747	negative chemotaxis
Sulba_0035	COG0601	transmembrane transport
Sulba_0036	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Sulba_0038	COG1124	(ABC) transporter
Sulba_0039	COG0534	Mate efflux family protein
Sulba_0042	COG1104	cysteine desulfurase activity
Sulba_0045	COG1355	regulation of microtubule-based process
Sulba_0049	COG1917	Cupin 2, conserved barrel domain protein
Sulba_0049	COG4977	sequence-specific DNA binding
Sulba_0053	COG3383	formate dehydrogenase (NAD+) activity
Sulba_0058	COG0129	dihydroxy-acid dehydratase activity
Sulba_0059	COG2095	MarC family integral membrane protein
Sulba_0064	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Sulba_0064	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Sulba_0065	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Sulba_0067	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Sulba_0071	COG1794	racemase activity, acting on amino acids and derivatives
Sulba_0072	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Sulba_0073	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Sulba_0074	COG0564	pseudouridine synthase activity
Sulba_0075	COG0179	Fumarylacetoacetate (FAA) hydrolase
Sulba_0077	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Sulba_0079	COG0107	imidazoleglycerol-phosphate synthase activity
Sulba_0081	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Sulba_0082	COG0517	IMP dehydrogenase activity
Sulba_0082	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Sulba_0083	COG1187	pseudouridine synthase activity
Sulba_0084	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Sulba_0084	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Sulba_0086	COG2257	FlhB HrpN YscU SpaS Family
Sulba_0088	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Sulba_0089	COG0237	dephospho-CoA kinase activity
Sulba_0090	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Sulba_0092	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Sulba_0096	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Sulba_0097	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Sulba_0098	COG1368	sulfuric ester hydrolase activity
Sulba_0100	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Sulba_0101	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Sulba_0102	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Sulba_0103	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Sulba_0104	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
Sulba_0107	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Sulba_0108	COG0723	plastoquinol--plastocyanin reductase activity
Sulba_0109	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Sulba_0111	COG1127	ABC transporter
Sulba_0115	COG0745	RESPONSE REGULATOR receiver
Sulba_0116	COG5002	protein histidine kinase activity
Sulba_0118	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Sulba_0120	COG1666	GTP binding
Sulba_0121	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Sulba_0122	COG0754	glutathionylspermidine amidase activity
Sulba_0127	COG0348	domain, Protein
Sulba_0128	COG0840	transmembrane signaling receptor activity
Sulba_0128	COG3290	protein histidine kinase activity
Sulba_0129	COG0840	transmembrane signaling receptor activity
Sulba_0134	COG4191	Histidine kinase
Sulba_0138	COG3340	Belongs to the peptidase S51 family
Sulba_0139	COG0667	Aldo Keto reductase
Sulba_0140	COG0745	RESPONSE REGULATOR receiver
Sulba_0143	COG0765	amino acid transport
Sulba_0147	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Sulba_0148	COG1121	(ABC) transporter
Sulba_0149	COG0803	Belongs to the bacterial solute-binding protein 9 family
Sulba_0152	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Sulba_0154	COG0318	PFAM AMP-dependent synthetase and ligase
Sulba_0156	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sulba_0157	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sulba_0158	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sulba_0159	COG0649	NAD binding
Sulba_0163	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Sulba_0164	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sulba_0165	COG0839	Belongs to the complex I subunit 6 family
Sulba_0166	COG0713	ATP synthesis coupled electron transport
Sulba_0167	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Sulba_0169	COG1007	ATP synthesis coupled electron transport
Sulba_0171	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Sulba_0172	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Sulba_0175	COG0840	transmembrane signaling receptor activity
Sulba_0176	COG0840	transmembrane signaling receptor activity
Sulba_0177	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Sulba_0178	COG1546	Belongs to the CinA family
Sulba_0178	COG1058	Belongs to the CinA family
Sulba_0180	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Sulba_0181	COG0254	rRNA binding
Sulba_0182	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Sulba_0183	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Sulba_0186	COG0436	Aminotransferase
Sulba_0187	COG0460	homoserine dehydrogenase
Sulba_0188	COG0792	nuclease activity
Sulba_0189	COG3118	belongs to the thioredoxin family
Sulba_0190	COG0492	ferredoxin-NADP+ reductase activity
Sulba_0191	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Sulba_0192	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Sulba_0195	COG0140	phosphoribosyl-ATP diphosphatase activity
Sulba_0195	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Sulba_0198	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Sulba_0200	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Sulba_0201	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Sulba_0202	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Sulba_0203	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Sulba_0204	COG1077	Cell shape determining protein MreB Mrl
Sulba_0206	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Sulba_0211	COG0489	protein tyrosine kinase activity
Sulba_0212	COG1342	Belongs to the UPF0251 family
Sulba_0216	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Sulba_0217	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Sulba_0218	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Sulba_0219	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Sulba_0220	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Sulba_0221	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Sulba_0222	COG0835	chemotaxis
Sulba_0222	COG0784	Response regulator, receiver
Sulba_0223	COG0643	Histidine kinase
Sulba_0223	COG2198	Histidine kinase
Sulba_0224	COG0835	chemotaxis
Sulba_0226	COG0560	Phosphoserine phosphatase
Sulba_0230	COG0193	aminoacyl-tRNA hydrolase activity
Sulba_0232	COG0019	diaminopimelate decarboxylase activity
Sulba_0234	COG1605	Chorismate mutase
Sulba_0234	COG0077	Prephenate dehydratase
Sulba_0235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Sulba_0236	COG1766	The M ring may be actively involved in energy transduction
Sulba_0237	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Sulba_0239	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Sulba_0240	COG0735	belongs to the Fur family
Sulba_0241	COG0450	alkyl hydroperoxide reductase
Sulba_0243	COG0105	UTP biosynthetic process
Sulba_0245	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Sulba_0246	COG0416	fatty acid biosynthetic process
Sulba_0247	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Sulba_0248	COG0287	Prephenate dehydrogenase
Sulba_0249	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Sulba_0251	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Sulba_0253	COG0745	RESPONSE REGULATOR receiver
Sulba_0255	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Sulba_0257	COG0157	Belongs to the NadC ModD family
Sulba_0258	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Sulba_0261	COG0850	regulation of cytokinetic process
Sulba_0262	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Sulba_0264	COG0083	homoserine kinase activity
Sulba_0266	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Sulba_0268	COG0779	Required for maturation of 30S ribosomal subunits
Sulba_0269	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Sulba_0269	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Sulba_0272	COG1278	Cold shock
Sulba_0273	COG5002	protein histidine kinase activity
Sulba_0274	COG0745	RESPONSE REGULATOR receiver
Sulba_0276	COG3258	Cytochrome c
Sulba_0278	COG1242	4 iron, 4 sulfur cluster binding
Sulba_0281	COG0243	molybdopterin cofactor binding
Sulba_0282	COG0437	4 iron, 4 sulfur cluster binding
Sulba_0283	COG3301	Polysulphide reductase, NrfD
Sulba_0284	COG3300	MHYT domain
Sulba_0284	COG5001	Diguanylate cyclase
Sulba_0286	COG0437	4 iron, 4 sulfur cluster binding
Sulba_0287	COG3301	Polysulphide reductase, NrfD
Sulba_0288	COG0745	RESPONSE REGULATOR receiver
Sulba_0289	COG5002	protein histidine kinase activity
Sulba_0291	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Sulba_0292	COG2814	Major facilitator Superfamily
Sulba_0293	COG1227	inorganic diphosphatase activity
Sulba_0296	COG1570	exodeoxyribonuclease VII activity
Sulba_0301	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Sulba_0302	COG0697	spore germination
Sulba_0303	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Sulba_0304	COG0583	DNA-binding transcription factor activity
Sulba_0305	COG2855	membrane
Sulba_0307	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Sulba_0308	COG0616	signal peptide processing
Sulba_0309	COG0402	S-adenosylhomocysteine deaminase activity
Sulba_0310	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Sulba_0311	COG0006	proline dipeptidase activity
Sulba_0312	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Sulba_0313	COG1419	protein localization to endoplasmic reticulum
Sulba_0314	COG0455	bacterial-type flagellum organization
Sulba_0316	COG1191	sigma factor activity
Sulba_0317	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Sulba_0318	COG1776	CheC inhibitor of MCP methylation
Sulba_0318	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Sulba_0321	COG0463	Glycosyl transferase, family 2
Sulba_0323	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Sulba_0327	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Sulba_0328	COG0481	GTPase activity
Sulba_0338	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Sulba_0340	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Sulba_0341	COG0731	radical SAM domain protein
Sulba_0347	COG1204	response to ionizing radiation
Sulba_0351	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Sulba_0352	COG0540	Belongs to the ATCase OTCase family
Sulba_0355	COG2200	EAL domain
Sulba_0355	COG3287	FIST C domain
Sulba_0355	COG2199	diguanylate cyclase activity
Sulba_0357	COG3118	belongs to the thioredoxin family
Sulba_0359	COG4336	lyase activity
Sulba_0363	COG4628	conserved protein (DUF2132)
Sulba_0364	COG4221	oxidoreductase activity
Sulba_0367	COG0683	leucine binding
Sulba_0368	COG0559	Belongs to the binding-protein-dependent transport system permease family
Sulba_0371	COG0410	ABC transporter
Sulba_0372	COG1012	belongs to the aldehyde dehydrogenase family
Sulba_0374	COG3022	response to hydroperoxide
Sulba_0379	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Sulba_0380	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Sulba_0383	COG0250	Participates in transcription elongation, termination and antitermination
Sulba_0384	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Sulba_0385	COG0081	regulation of translation
Sulba_0386	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Sulba_0387	COG0222	ribosome binding
Sulba_0388	COG0085	RNA polymerase activity
Sulba_0389	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Sulba_0390	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Sulba_0393	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Sulba_0394	COG2011	ABC-type metal ion transport system permease component
Sulba_0395	COG1464	Belongs to the NlpA lipoprotein family
Sulba_0400	COG0840	transmembrane signaling receptor activity
Sulba_0401	COG3852	Histidine kinase
Sulba_0403	COG1034	ATP synthesis coupled electron transport
Sulba_0404	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Sulba_0405	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sulba_0406	COG0839	Belongs to the complex I subunit 6 family
Sulba_0407	COG0713	ATP synthesis coupled electron transport
Sulba_0408	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Sulba_0410	COG1007	ATP synthesis coupled electron transport
Sulba_0412	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
Sulba_0413	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sulba_0413	COG0649	NAD binding
Sulba_0414	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sulba_0415	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sulba_0418	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Sulba_0422	COG0357	Ribosomal RNA small subunit methyltransferase G
Sulba_0423	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Sulba_0424	COG1970	mechanosensitive ion channel activity
Sulba_0425	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Sulba_0426	COG0113	porphobilinogen synthase activity
Sulba_0427	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Sulba_0429	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Sulba_0430	COG0247	lactate metabolic process
Sulba_0433	COG2026	Addiction module toxin, RelE StbE family
Sulba_0434	COG2814	Major facilitator Superfamily
Sulba_0435	COG3012	SEC-C Motif Domain Protein
Sulba_0438	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Sulba_0440	COG1053	succinate dehydrogenase
Sulba_0441	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Sulba_0443	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Sulba_0444	COG0628	permease
Sulba_0445	COG2255	four-way junction helicase activity
Sulba_0446	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Sulba_0448	COG0159	tryptophan synthase activity
Sulba_0453	COG1136	(ABC) transporter
Sulba_0454	COG1684	flagellar biosynthetic protein fliR
Sulba_0456	COG0194	GDP metabolic process
Sulba_0457	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Sulba_0458	COG0018	arginyl-trna synthetase
Sulba_0460	COG3706	GGDEF domain
Sulba_0463	COG0735	belongs to the Fur family
Sulba_0465	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Sulba_0468	COG0149	triose-phosphate isomerase activity
Sulba_0469	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Sulba_0470	COG0601	transmembrane transport
Sulba_0472	COG0195	Participates in both transcription termination and antitermination
Sulba_0479	COG0037	tRNA processing
Sulba_0480	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Sulba_0481	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Sulba_0482	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Sulba_0488	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Sulba_0489	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Sulba_0493	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Sulba_0494	COG1151	hydroxylamine reductase activity
Sulba_0503	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Sulba_0504	COG0513	Belongs to the DEAD box helicase family
Sulba_0505	COG2610	gluconate transmembrane transporter activity
Sulba_0506	COG1944	ATP diphosphatase activity
Sulba_0512	COG0745	RESPONSE REGULATOR receiver
Sulba_0514	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Sulba_0525	COG0559	Belongs to the binding-protein-dependent transport system permease family
Sulba_0529	COG1333	cytochrome c biogenesis protein
Sulba_0529	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Sulba_0538	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Sulba_0541	COG0517	IMP dehydrogenase activity
Sulba_0541	COG0516	GMP reductase activity
Sulba_0542	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Sulba_0545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Sulba_0546	COG0436	Aminotransferase
Sulba_0549	COG1193	negative regulation of DNA recombination
Sulba_0550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Sulba_0551	COG0251	oxidation-reduction process
Sulba_0552	COG0579	oxidoreductase
Sulba_0558	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Sulba_0559	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Sulba_0560	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Sulba_0561	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Sulba_0562	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Sulba_0563	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Sulba_0563	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Sulba_0564	COG1192	Involved in chromosome partitioning
Sulba_0565	COG1475	DNA binding
Sulba_0567	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Sulba_0568	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Sulba_0570	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Sulba_0571	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Sulba_0572	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Sulba_0573	COG0811	peptide transport
Sulba_0574	COG0848	biopolymer transport protein
Sulba_0576	COG0823	Involved in the tonB-independent uptake of proteins
Sulba_0577	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Sulba_0577	COG2885	chlorophyll binding
Sulba_0579	COG1047	Peptidyl-prolyl cis-trans
Sulba_0581	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Sulba_0582	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Sulba_0583	COG0037	tRNA processing
Sulba_0585	COG0067	glutamate synthase
Sulba_0585	COG0069	glutamate synthase activity
Sulba_0585	COG0070	glutamate synthase
Sulba_0586	COG0493	'glutamate synthase
Sulba_0588	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Sulba_0589	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Sulba_0590	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Sulba_0592	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Sulba_0596	COG1776	CheC inhibitor of MCP methylation
Sulba_0596	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Sulba_0597	COG0708	Exodeoxyribonuclease III
Sulba_0600	COG0748	coenzyme F420 binding
Sulba_0603	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Sulba_0605	COG1113	amino acid transport
Sulba_0606	COG0730	response to heat
Sulba_0607	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Sulba_0608	COG1301	dicarboxylic acid transport
Sulba_0612	COG4565	transcriptional regulatory protein
Sulba_0613	COG3290	protein histidine kinase activity
Sulba_0614	COG3180	Ammonia monooxygenase
Sulba_0617	COG2301	Belongs to the HpcH HpaI aldolase family
Sulba_0619	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
Sulba_0619	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
Sulba_0620	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Sulba_0620	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Sulba_0621	COG1971	Probably functions as a manganese efflux pump
Sulba_0623	COG0484	heat shock protein binding
Sulba_0625	COG0745	RESPONSE REGULATOR receiver
Sulba_0627	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Sulba_0629	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Sulba_0630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Sulba_0633	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Sulba_0634	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Sulba_0637	COG3706	GGDEF domain
Sulba_0639	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Sulba_0644	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Sulba_0645	COG0322	excinuclease ABC activity
Sulba_0647	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Sulba_0649	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Sulba_0649	COG0519	Catalyzes the synthesis of GMP from XMP
Sulba_0651	COG0151	Belongs to the GarS family
Sulba_0653	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Sulba_0655	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Sulba_0659	COG0511	ligase activity, forming carbon-carbon bonds
Sulba_0660	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
Sulba_0661	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Sulba_0662	COG0165	Argininosuccinate lyase
Sulba_0663	COG0537	adenosine 5'-monophosphoramidase activity
Sulba_0664	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Sulba_0665	COG0072	phenylalanine-tRNA ligase activity
Sulba_0665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Sulba_0666	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Sulba_0667	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Sulba_0668	COG1185	polyribonucleotide nucleotidyltransferase activity
Sulba_0668	COG0539	negative regulation of cytoplasmic translation
Sulba_0670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Sulba_0673	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Sulba_0679	COG0693	protein deglycase activity
Sulba_0683	COG2081	HI0933 family
Sulba_0685	COG0840	transmembrane signaling receptor activity
Sulba_0686	COG0587	DNA-directed DNA polymerase activity
Sulba_0689	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Sulba_0690	COG0569	domain protein
Sulba_0693	COG0772	Belongs to the SEDS family
Sulba_0694	COG0564	pseudouridine synthase activity
Sulba_0695	COG0366	Alpha amylase catalytic
Sulba_0695	COG3103	Sh3 type 3 domain protein
Sulba_0696	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Sulba_0697	COG2884	Cell division ATP-binding protein ftsE
Sulba_0700	COG0528	UMP kinase activity
Sulba_0701	COG1758	RNA polymerase activity
Sulba_0703	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Sulba_0705	COG0860	N-Acetylmuramoyl-L-alanine amidase
Sulba_0707	COG0563	adenylate kinase activity
Sulba_0708	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Sulba_0710	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Sulba_0711	COG0497	DNA recombination
Sulba_0712	COG1620	l-lactate permease
Sulba_0713	COG3706	GGDEF domain
Sulba_0714	COG0084	hydrolase, TatD family'
Sulba_0715	COG1388	LysM domain
Sulba_0715	COG0741	lytic transglycosylase activity
Sulba_0716	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Sulba_0717	COG0131	Imidazoleglycerol-phosphate dehydratase
Sulba_0718	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Sulba_0721	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Sulba_0724	COG0768	penicillin binding
Sulba_0725	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Sulba_0727	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Sulba_0727	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Sulba_0729	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Sulba_0734	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Sulba_0735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Sulba_0736	COG0583	DNA-binding transcription factor activity
Sulba_0737	COG1053	succinate dehydrogenase
Sulba_0738	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Sulba_0739	COG2048	Heterodisulfide reductase, subunit B
Sulba_0742	COG3852	Histidine kinase
Sulba_0752	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Sulba_0757	COG0659	secondary active sulfate transmembrane transporter activity
Sulba_0761	COG1136	(ABC) transporter
Sulba_0766	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Sulba_0766	COG1333	cytochrome c biogenesis protein
Sulba_0767	COG3301	Polysulphide reductase, NrfD
Sulba_0768	COG0437	4 iron, 4 sulfur cluster binding
Sulba_0769	COG0545	Peptidyl-prolyl cis-trans isomerase
Sulba_0770	COG0484	heat shock protein binding
Sulba_0771	COG3852	Histidine kinase
Sulba_0772	COG0745	RESPONSE REGULATOR receiver
Sulba_0773	COG3005	denitrification pathway
Sulba_0775	COG1333	cytochrome c biogenesis protein
Sulba_0775	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Sulba_0780	COG0840	transmembrane signaling receptor activity
Sulba_0780	COG3290	protein histidine kinase activity
Sulba_0782	COG1346	cytolysis
Sulba_0785	COG0840	transmembrane signaling receptor activity
Sulba_0789	COG0848	biopolymer transport protein
Sulba_0790	COG0811	peptide transport
Sulba_0792	COG3328	transposase activity
Sulba_0793	COG3328	transposase activity
Sulba_0795	COG0243	molybdopterin cofactor binding
Sulba_0796	COG0437	4 iron, 4 sulfur cluster binding
Sulba_0797	COG0348	domain, Protein
Sulba_0798	COG3043	anaerobic respiration
Sulba_0808	COG0745	RESPONSE REGULATOR receiver
Sulba_0809	COG4191	Histidine kinase
Sulba_0811	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Sulba_0812	COG3069	C4-dicarboxylate transmembrane transporter activity
Sulba_0813	COG2199	diguanylate cyclase activity
Sulba_0813	COG3287	FIST C domain
Sulba_0813	COG2200	EAL domain
Sulba_0814	COG0688	phosphatidylethanolamine metabolic process
Sulba_0815	COG0513	Belongs to the DEAD box helicase family
Sulba_0818	COG2207	Transcriptional regulator
Sulba_0818	COG1917	Cupin 2, conserved barrel domain protein
Sulba_0821	COG2084	Dehydrogenase
Sulba_0822	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Sulba_0823	COG1280	lysine exporter protein (LysE YggA)
Sulba_0828	COG0217	transcriptional regulatory protein
Sulba_0844	COG0519	Catalyzes the synthesis of GMP from XMP
Sulba_0845	COG3045	CreA protein
Sulba_0846	COG2353	YceI-like domain
Sulba_0847	COG1309	transcriptional regulator
Sulba_0850	COG1305	Transglutaminase-like
Sulba_0852	COG2308	Evidence 4 Homologs of previously reported genes of
Sulba_0855	COG2217	Heavy metal translocating P-type atpase
Sulba_0861	COG0437	4 iron, 4 sulfur cluster binding
Sulba_0863	COG3290	protein histidine kinase activity
Sulba_0863	COG0840	transmembrane signaling receptor activity
Sulba_0865	COG0352	thiamine-phosphate diphosphorylase activity
Sulba_0867	COG1966	Carbon starvation protein
Sulba_0868	COG0745	RESPONSE REGULATOR receiver
Sulba_0875	COG1139	Iron-sulfur cluster binding protein
Sulba_0876	COG1556	Lactate utilization protein
Sulba_0877	COG0697	spore germination
Sulba_0880	COG2176	DNA-directed DNA polymerase activity
Sulba_0881	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Sulba_0883	COG0501	Belongs to the peptidase M48B family
Sulba_0886	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Sulba_0887	COG2201	protein-glutamate methylesterase activity
Sulba_0888	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Sulba_0890	COG0133	tryptophan synthase activity
Sulba_0893	COG0698	ribose 5-phosphate isomerase
Sulba_0894	COG1994	Peptidase M50
Sulba_0895	COG0681	Belongs to the peptidase S26 family
Sulba_0896	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Sulba_0897	COG3381	protein complex oligomerization
Sulba_0899	COG0437	4 iron, 4 sulfur cluster binding
Sulba_0900	COG0243	molybdopterin cofactor binding
Sulba_0902	COG0745	RESPONSE REGULATOR receiver
Sulba_0904	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Sulba_0907	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Sulba_0908	COG0612	Peptidase, M16
Sulba_0909	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Sulba_0915	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
Sulba_0916	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Sulba_0917	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Sulba_0918	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Sulba_0919	COG0629	single-stranded DNA binding
Sulba_0920	COG0360	Binds together with S18 to 16S ribosomal RNA
Sulba_0922	COG0557	exoribonuclease II activity
Sulba_0924	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Sulba_0925	COG2894	cell division
Sulba_0926	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Sulba_0929	COG0730	response to heat
Sulba_0930	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Sulba_0931	COG2860	membrane
Sulba_0932	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Sulba_0934	COG0736	holo-[acyl-carrier-protein] synthase activity
Sulba_0935	COG1580	Controls the rotational direction of flagella during chemotaxis
Sulba_0936	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Sulba_0937	COG0552	protein localization to endoplasmic reticulum
Sulba_0938	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Sulba_0940	COG1418	mRNA catabolic process
Sulba_0941	COG1132	(ABC) transporter
Sulba_0947	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Sulba_0948	COG0745	RESPONSE REGULATOR receiver
Sulba_0952	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Sulba_0959	COG1518	maintenance of DNA repeat elements
Sulba_0977	COG4974	Belongs to the 'phage' integrase family
Sulba_0982	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Sulba_0986	COG0824	Thioesterase
Sulba_0988	COG1573	uracil-dna glycosylase
Sulba_0991	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Sulba_0993	COG0745	RESPONSE REGULATOR receiver
Sulba_0994	COG5002	protein histidine kinase activity
Sulba_0994	COG5001	Diguanylate cyclase
Sulba_0996	COG0426	domain, Protein
Sulba_1003	COG2040	homocysteine
Sulba_1005	COG2205	protein histidine kinase activity
Sulba_1005	COG0784	Response regulator, receiver
Sulba_1006	COG3437	response regulator, receiver
Sulba_1008	COG1433	Dinitrogenase iron-molybdenum cofactor
Sulba_1010	COG0716	FMN binding
Sulba_1015	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Sulba_1019	COG0628	permease
Sulba_1025	COG1451	nucleotide metabolic process
Sulba_1027	COG0697	spore germination
Sulba_1029	COG3706	GGDEF domain
Sulba_1036	COG0840	transmembrane signaling receptor activity
Sulba_1037	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
Sulba_1039	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Sulba_1041	COG1272	protein, Hemolysin III
Sulba_1042	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Sulba_1050	COG5002	protein histidine kinase activity
Sulba_1055	COG0493	'glutamate synthase
Sulba_1056	COG0375	protein maturation
Sulba_1057	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Sulba_1059	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sulba_1061	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sulba_1062	COG1047	Peptidyl-prolyl cis-trans
Sulba_1072	COG1396	sequence-specific DNA binding
Sulba_1073	COG0667	Aldo Keto reductase
Sulba_1074	COG1053	succinate dehydrogenase
Sulba_1081	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Sulba_1082	COG0585	pseudouridine synthase activity
Sulba_1085	COG0475	glutathione-regulated potassium exporter activity
Sulba_1085	COG0569	domain protein
Sulba_1088	COG3852	Histidine kinase
Sulba_1089	COG2200	EAL domain
Sulba_1089	COG3287	FIST C domain
Sulba_1089	COG2199	diguanylate cyclase activity
Sulba_1090	COG0351	phosphomethylpyrimidine kinase
Sulba_1091	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
Sulba_1092	COG0428	transporter
Sulba_1093	COG1234	tRNA 3'-trailer cleavage
Sulba_1096	COG0488	(ABC) transporter
Sulba_1097	COG1360	Flagellar Motor Protein
Sulba_1098	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Sulba_1103	COG2207	Transcriptional regulator
Sulba_1104	COG1979	alcohol dehydrogenase
Sulba_1107	COG0778	Nitroreductase
Sulba_1108	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Sulba_1110	COG0415	Belongs to the DNA photolyase family
Sulba_1114	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Sulba_1117	COG0742	ribosomal rna small subunit methyltransferase
Sulba_1118	COG1706	bacterial-type flagellum-dependent cell motility
Sulba_1119	COG3951	Flagellar rod assembly protein muramidase FlgJ
Sulba_1123	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Sulba_1125	COG0659	secondary active sulfate transmembrane transporter activity
Sulba_1126	COG1942	4-Oxalocrotonate Tautomerase
Sulba_1127	COG0356	it plays a direct role in the translocation of protons across the membrane
Sulba_1129	COG0352	thiamine-phosphate diphosphorylase activity
Sulba_1133	COG0101	tRNA pseudouridine synthase activity
Sulba_1137	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Sulba_1138	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Sulba_1139	COG1338	Plays a role in the flagellum-specific transport system
Sulba_1141	COG1032	radical SAM domain protein
Sulba_1142	COG0166	Belongs to the GPI family
Sulba_1144	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
Sulba_1145	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
Sulba_1146	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
Sulba_1147	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Sulba_1149	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Sulba_1155	COG0298	carbon dioxide binding
Sulba_1157	COG0309	Hydrogenase expression formation protein (HypE)
Sulba_1158	COG0375	protein maturation
Sulba_1160	COG0546	phosphoglycolate phosphatase activity
Sulba_1164	COG0039	L-malate dehydrogenase activity
Sulba_1165	COG0045	succinate-CoA ligase (ADP-forming) activity
Sulba_1166	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Sulba_1169	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Sulba_1169	COG0674	pyruvate-flavodoxin oxidoreductase activity
Sulba_1170	COG3962	Belongs to the TPP enzyme family
Sulba_1172	COG0840	transmembrane signaling receptor activity
Sulba_1174	COG0114	fumarate hydratase activity
Sulba_1175	COG2183	response to ionizing radiation
Sulba_1182	COG0840	transmembrane signaling receptor activity
Sulba_1183	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Sulba_1184	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Sulba_1187	COG0589	response to stress
Sulba_1188	COG1012	belongs to the aldehyde dehydrogenase family
Sulba_1189	COG0471	metal ion transport
Sulba_1190	COG0778	Nitroreductase
Sulba_1191	COG2249	NAD(P)H dehydrogenase (quinone) activity
Sulba_1192	COG1733	regulation of RNA biosynthetic process
Sulba_1195	COG1472	Belongs to the glycosyl hydrolase 3 family
Sulba_1196	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
Sulba_1197	COG2056	Na+-H+ antiporter family
Sulba_1199	COG0475	glutathione-regulated potassium exporter activity
Sulba_1200	COG2095	MarC family integral membrane protein
Sulba_1202	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Sulba_1203	COG0750	zinc metalloprotease
Sulba_1204	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Sulba_1205	COG1028	Short-chain dehydrogenase reductase Sdr
Sulba_1206	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Sulba_1208	COG0167	dihydroorotate dehydrogenase activity
Sulba_1209	COG1132	(ABC) transporter
Sulba_1210	COG0215	cysteine-tRNA ligase activity
Sulba_1211	COG0728	peptidoglycan biosynthetic process
Sulba_1214	COG1181	Belongs to the D-alanine--D-alanine ligase family
Sulba_1217	COG1254	Belongs to the acylphosphatase family
Sulba_1218	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Sulba_1219	COG0857	belongs to the CobB CobQ family
Sulba_1219	COG0280	phosphate acetyltransferase
Sulba_1220	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Sulba_1233	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Sulba_1234	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Sulba_1235	COG0359	binds to the 23S rRNA
Sulba_1237	COG0137	argininosuccinate synthase activity
Sulba_1238	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Sulba_1239	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Sulba_1240	COG0802	atpase or kinase
Sulba_1241	COG1137	ATPase activity
Sulba_1242	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Sulba_1254	COG3328	transposase activity
Sulba_1258	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Sulba_1264	COG0582	viral genome integration into host DNA
Sulba_1266	COG0776	regulation of translation
Sulba_1268	COG1674	ftsk spoiiie
Sulba_1268	COG1196	nuclear chromosome segregation
Sulba_1269	COG1049	propionate catabolic process, 2-methylcitrate cycle
Sulba_1270	COG1047	Peptidyl-prolyl cis-trans
Sulba_1271	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Sulba_1271	COG0574	Belongs to the PEP-utilizing enzyme family
Sulba_1272	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Sulba_1276	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Sulba_1277	COG1832	CoA-binding protein
Sulba_1278	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Sulba_1280	COG1126	abc transporter atp-binding protein
Sulba_1281	COG0765	amino acid transport
Sulba_1282	COG4597	amino acid ABC transporter
Sulba_1283	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Sulba_1284	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Sulba_1287	COG4172	Belongs to the ABC transporter superfamily
Sulba_1288	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Sulba_1292	COG0727	PFAM Uncharacterised protein family (UPF0153)
Sulba_1294	COG0134	indole-3-glycerol-phosphate synthase activity
Sulba_1296	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
Sulba_1301	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Sulba_1302	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Sulba_1305	COG0446	pyridine nucleotide-disulphide oxidoreductase
Sulba_1308	COG0028	Belongs to the TPP enzyme family
Sulba_1309	COG0440	acetolactate synthase activity
Sulba_1310	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Sulba_1312	COG0493	'glutamate synthase
Sulba_1314	COG1045	serine acetyltransferase
Sulba_1315	COG1166	arginine decarboxylase activity
Sulba_1316	COG0124	histidyl-tRNA synthetase
Sulba_1318	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Sulba_1319	COG0163	prenyltransferase activity
Sulba_1323	COG0303	'Molybdopterin
Sulba_1324	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Sulba_1326	COG1691	(AIR) carboxylase
Sulba_1327	COG1606	tRNA processing
Sulba_1328	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Sulba_1329	COG3875	lactate racemase activity
Sulba_1330	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
Sulba_1330	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Sulba_1333	COG3852	Histidine kinase
Sulba_1334	COG0745	RESPONSE REGULATOR receiver
Sulba_1338	COG0582	viral genome integration into host DNA
Sulba_1339	COG0343	queuine tRNA-ribosyltransferase activity
Sulba_1341	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Sulba_1343	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Sulba_1344	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Sulba_1353	COG3201	nicotinamide mononucleotide transporter
Sulba_1355	COG0242	peptide deformylase activity
Sulba_1356	COG1309	transcriptional regulator
Sulba_1364	COG3468	outer membrane autotransporter barrel domain protein
Sulba_1365	COG4191	Histidine kinase
Sulba_1366	COG0745	RESPONSE REGULATOR receiver
Sulba_1368	COG2831	hemolysin activation secretion protein
Sulba_1369	COG3210	domain, Protein
Sulba_1369	COG3210	domain, Protein
Sulba_1373	COG3328	transposase activity
Sulba_1377	COG0840	transmembrane signaling receptor activity
Sulba_1379	COG1139	Iron-sulfur cluster binding protein
Sulba_1380	COG1592	Rubrerythrin
Sulba_1382	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Sulba_1386	COG0442	prolyl-tRNA aminoacylation
Sulba_1387	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Sulba_1388	COG0142	geranyltranstransferase activity
Sulba_1392	COG1959	2 iron, 2 sulfur cluster binding
Sulba_1394	COG3706	GGDEF domain
Sulba_1395	COG0525	valine-tRNA ligase activity
Sulba_1396	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Sulba_1397	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Sulba_1398	COG0521	Mo-molybdopterin cofactor biosynthetic process
Sulba_1399	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Sulba_1402	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Sulba_1403	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Sulba_1405	COG2195	Cleaves the N-terminal amino acid of tripeptides
Sulba_1407	COG0500	methyltransferase
Sulba_1410	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Sulba_1412	COG1663	tetraacyldisaccharide 4'-kinase activity
Sulba_1413	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Sulba_1414	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Sulba_1415	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Sulba_1417	COG4232	protein-disulfide reductase activity
Sulba_1420	COG0443	Heat shock 70 kDa protein
Sulba_1421	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Sulba_1422	COG1420	regulation of RNA biosynthetic process
Sulba_1425	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Sulba_1426	COG1959	2 iron, 2 sulfur cluster binding
Sulba_1427	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Sulba_1428	COG2404	hydrolase activity, acting on ester bonds
Sulba_1430	COG2226	methyltransferase
Sulba_1431	COG0196	riboflavin kinase activity
Sulba_1433	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Sulba_1434	COG0730	response to heat
Sulba_1436	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Sulba_1439	COG0527	aspartate kinase activity
Sulba_1440	COG0494	nUDIX hydrolase
Sulba_1441	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Sulba_1443	COG0789	Transcriptional regulator
Sulba_1444	COG0484	heat shock protein binding
Sulba_1445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Sulba_1446	COG0745	RESPONSE REGULATOR receiver
Sulba_1447	COG2205	protein histidine kinase activity
Sulba_1450	COG0653	protein targeting
Sulba_1452	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Sulba_1453	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Sulba_1455	COG0706	membrane insertase activity
Sulba_1458	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Sulba_1462	COG0542	response to heat
Sulba_1463	COG0793	Belongs to the peptidase S41A family
Sulba_1465	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Sulba_1466	COG0047	phosphoribosylformylglycinamidine synthase activity
Sulba_1468	COG0204	Acyl-transferase
Sulba_1469	COG0326	Molecular chaperone. Has ATPase activity
Sulba_1470	COG0784	Response regulator, receiver
Sulba_1471	COG3920	Histidine kinase
Sulba_1474	COG1331	Highly conserved protein containing a thioredoxin domain
Sulba_1481	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Sulba_1485	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Sulba_1489	COG0275	rRNA processing
Sulba_1490	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Sulba_1492	COG0849	cell division
Sulba_1493	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Sulba_1495	COG2890	protein-(glutamine-N5) methyltransferase activity
Sulba_1495	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Sulba_1496	COG0501	Belongs to the peptidase M48B family
Sulba_1499	COG0840	transmembrane signaling receptor activity
Sulba_1500	COG2151	metal-sulfur cluster biosynthetic enzyme
Sulba_1503	COG0138	bifunctional purine biosynthesis protein purh
Sulba_1504	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Sulba_1506	COG1607	acyl-coa hydrolase
Sulba_1507	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Sulba_1510	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Sulba_1512	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Sulba_1513	COG0805	protein transport
Sulba_1514	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Sulba_1516	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Sulba_1517	COG1022	Amp-dependent synthetase and ligase
Sulba_1519	COG4206	TonB-dependent receptor
Sulba_1520	COG2205	protein histidine kinase activity
Sulba_1521	COG0745	RESPONSE REGULATOR receiver
Sulba_1522	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Sulba_1523	COG0569	domain protein
Sulba_1524	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Sulba_1525	COG1253	flavin adenine dinucleotide binding
Sulba_1527	COG0745	RESPONSE REGULATOR receiver
Sulba_1531	COG1629	transport
Sulba_1531	COG4774	siderophore transport
Sulba_1537	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Sulba_1538	COG1410	methionine synthase
Sulba_1538	COG0646	methionine synthase
Sulba_1539	COG0840	transmembrane signaling receptor activity
Sulba_1541	COG0004	ammonium transporteR
Sulba_1542	COG0347	Belongs to the P(II) protein family
Sulba_1544	COG2022	thiamine diphosphate biosynthetic process
Sulba_1545	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Sulba_1554	COG0288	reversible hydration of carbon dioxide
Sulba_1555	COG3123	guanosine phosphorylase activity
Sulba_1556	COG2081	HI0933 family
Sulba_1558	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Sulba_1559	COG0788	formyltetrahydrofolate deformylase activity
Sulba_1560	COG0617	tRNA 3'-terminal CCA addition
Sulba_1563	COG0473	3-isopropylmalate dehydrogenase activity
Sulba_1564	COG0066	3-isopropylmalate dehydratase activity
Sulba_1566	COG4115	mRNA cleavage
Sulba_1568	COG1119	ATPase activity
Sulba_1570	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Sulba_1572	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Sulba_1576	COG4895	conserved protein (DUF2196)
Sulba_1579	COG3706	GGDEF domain
Sulba_1581	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
Sulba_1582	COG4895	conserved protein (DUF2196)
Sulba_1583	COG0514	ATP-dependent DNA helicase (RecQ)
Sulba_1586	COG0513	Belongs to the DEAD box helicase family
Sulba_1588	COG2824	Alkylphosphonate utilization operon protein PhnA
Sulba_1590	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Sulba_1592	COG4786	Flagellar basal body rod
Sulba_1593	COG4786	Flagellar basal body rod
Sulba_1594	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Sulba_1610	COG4206	TonB-dependent receptor
Sulba_1611	COG0745	RESPONSE REGULATOR receiver
Sulba_1613	COG0783	Belongs to the Dps family
Sulba_1615	COG1131	(ABC) transporter
Sulba_1617	COG3706	GGDEF domain
Sulba_1620	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Sulba_1620	COG1918	ferrous iron import across plasma membrane
Sulba_1621	COG1918	ferrous iron import across plasma membrane
Sulba_1623	COG4771	TonB-dependent receptor
Sulba_1626	COG4771	TonB-dependent receptor
Sulba_1631	COG0811	peptide transport
Sulba_1634	COG1132	(ABC) transporter
Sulba_1636	COG4771	TonB-dependent receptor
Sulba_1637	COG4771	TonB-dependent receptor
Sulba_1641	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Sulba_1642	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Sulba_1643	COG3162	membrane
Sulba_1644	COG0745	RESPONSE REGULATOR receiver
Sulba_1648	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Sulba_1649	COG1918	ferrous iron import across plasma membrane
Sulba_1652	COG3328	transposase activity
Sulba_1656	COG0598	Magnesium transport protein CorA
Sulba_1657	COG0739	heme binding
Sulba_1659	COG0277	FAD linked oxidase domain protein
Sulba_1660	COG1295	ribonuclease BN
Sulba_1662	COG0305	Participates in initiation and elongation during chromosome replication
Sulba_1663	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Sulba_1664	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Sulba_1669	COG0556	nucleotide-excision repair
Sulba_1671	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Sulba_1673	COG0135	phosphoribosylanthranilate isomerase activity
Sulba_1674	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Sulba_1676	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Sulba_1679	COG1692	metallophosphoesterase
Sulba_1680	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Sulba_1682	COG0739	heme binding
Sulba_1683	COG0285	dihydrofolate synthase activity
Sulba_1684	COG3706	GGDEF domain
Sulba_1686	COG0495	leucyl-tRNA aminoacylation
Sulba_1687	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Sulba_1688	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Sulba_1689	COG1862	Preprotein translocase
Sulba_1690	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Sulba_1691	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Sulba_1693	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Sulba_1694	COG0542	response to heat
Sulba_1695	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Sulba_1697	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Sulba_1698	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Sulba_1699	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Sulba_1700	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Sulba_1707	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Sulba_1713	COG0336	Belongs to the RNA methyltransferase TrmD family
Sulba_1714	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Sulba_1715	COG1837	Belongs to the UPF0109 family
Sulba_1716	COG0228	four-way junction DNA binding
Sulba_1717	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Sulba_1718	COG0564	pseudouridine synthase activity
Sulba_1719	COG1519	Transferase
Sulba_1721	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Sulba_1722	COG0752	glycyl-tRNA synthetase alpha subunit
Sulba_1724	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Sulba_1727	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Sulba_1728	COG0174	glutamine synthetase
Sulba_1730	COG0444	Belongs to the ABC transporter superfamily
Sulba_1731	COG0156	8-amino-7-oxononanoate synthase activity
Sulba_1732	COG0424	maF-like protein
Sulba_1734	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Sulba_1737	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Sulba_1740	COG1558	bacterial-type flagellum-dependent cell motility
Sulba_1741	COG1815	bacterial-type flagellum-dependent cell motility
Sulba_1742	COG0772	Belongs to the SEDS family
Sulba_1743	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Sulba_1746	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Sulba_1748	COG0697	spore germination
Sulba_1756	COG0512	Glutamine amidotransferase of anthranilate synthase
Sulba_1757	COG0784	Response regulator, receiver
Sulba_1757	COG5002	protein histidine kinase activity
Sulba_1757	COG2205	protein histidine kinase activity
Sulba_1760	COG2252	PERMEase
Sulba_1761	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Sulba_1762	COG3766	membrane
Sulba_1763	COG0133	tryptophan synthase activity
Sulba_1764	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Sulba_1765	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Sulba_1766	COG3706	GGDEF domain
Sulba_1773	COG0488	(ABC) transporter
Sulba_1778	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Sulba_1781	COG3706	GGDEF domain
Sulba_1781	COG0745	RESPONSE REGULATOR receiver
Sulba_1783	COG2171	N-acyltransferase activity
Sulba_1784	COG0489	protein tyrosine kinase activity
Sulba_1785	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Sulba_1785	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Sulba_1787	COG2046	Belongs to the sulfate adenylyltransferase family
Sulba_1788	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Sulba_1789	COG2353	YceI-like domain
Sulba_1790	COG1739	Uncharacterized protein family UPF0029
Sulba_1791	COG3842	ATPase activity
Sulba_1792	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Sulba_1799	COG1686	Belongs to the peptidase S11 family
Sulba_1802	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Sulba_1811	COG1271	oxidase subunit
Sulba_1812	COG1294	oxidase, subunit
Sulba_1816	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Sulba_1818	COG2207	Transcriptional regulator
Sulba_1818	COG1917	Cupin 2, conserved barrel domain protein
Sulba_1823	COG1011	Hydrolase
Sulba_1825	COG3639	organic phosphonate transmembrane transporter activity
Sulba_1826	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Sulba_1831	COG0284	orotidine-5'-phosphate decarboxylase activity
Sulba_1832	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Sulba_1833	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Sulba_1835	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Sulba_1836	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Sulba_1837	COG0697	spore germination
Sulba_1838	COG0668	transmembrane transport
Sulba_1839	COG1160	GTP binding
Sulba_1841	COG0180	Tryptophanyl-tRNA synthetase
Sulba_1842	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Sulba_1844	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Sulba_1845	COG1183	phosphatidylcholine synthase activity
Sulba_1846	COG0688	phosphatidylethanolamine metabolic process
Sulba_1847	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Sulba_1848	COG2264	protein methyltransferase activity
Sulba_1850	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Sulba_1851	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Sulba_1854	COG1086	Polysaccharide biosynthesis protein
Sulba_1855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Sulba_1857	COG1215	transferase activity, transferring glycosyl groups
Sulba_1860	COG1216	Glycosyl transferase, family 2
Sulba_1860	COG0463	Glycosyl transferase, family 2
Sulba_1862	COG0656	L-ascorbic acid biosynthetic process
Sulba_1865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Sulba_1870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Sulba_1872	COG0367	asparagine synthase
Sulba_1875	COG0438	transferase activity, transferring glycosyl groups
Sulba_1878	COG0728	peptidoglycan biosynthetic process
Sulba_1881	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Sulba_1882	COG1793	dna ligase
Sulba_1884	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Sulba_1891	COG0859	PFAM glycosyl transferase family 9
Sulba_1894	COG1083	cytidylyl-transferase
Sulba_1896	COG2089	acid synthase
Sulba_1898	COG1696	Membrane protein involved in D-alanine export
Sulba_1901	COG3642	lipopolysaccharide core region biosynthetic process
Sulba_1902	COG0859	PFAM glycosyl transferase family 9
Sulba_1905	COG3307	-O-antigen
Sulba_1906	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Sulba_1907	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Sulba_1907	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Sulba_1908	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Sulba_1909	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Sulba_1913	COG2217	Heavy metal translocating P-type atpase
Sulba_1914	COG5001	Diguanylate cyclase
Sulba_1914	COG5002	protein histidine kinase activity
Sulba_1915	COG3706	GGDEF domain
Sulba_1916	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Sulba_1920	COG0840	transmembrane signaling receptor activity
Sulba_1921	COG1984	allophanate hydrolase subunit 2
Sulba_1922	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Sulba_1924	COG0445	tRNA wobble uridine modification
Sulba_1925	COG0723	plastoquinol--plastocyanin reductase activity
Sulba_1926	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Sulba_1927	COG2857	Cytochrome c1
Sulba_1928	COG0825	malonyl-CoA metabolic process
Sulba_1929	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Sulba_1930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Sulba_1932	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Sulba_1933	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Sulba_1934	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Sulba_1936	COG3328	transposase activity
Sulba_1938	COG0582	viral genome integration into host DNA
Sulba_1939	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Sulba_1940	COG4943	cyclic-guanylate-specific phosphodiesterase activity
Sulba_1942	COG0390	transport system, permease component
Sulba_1946	COG0306	phosphate transporter
Sulba_1947	COG0513	Belongs to the DEAD box helicase family
Sulba_1948	COG1671	Belongs to the UPF0178 family
Sulba_1952	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Sulba_1954	COG0573	inorganic phosphate transmembrane transporter activity
Sulba_1955	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Sulba_1957	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Sulba_1958	COG0651	ATP synthesis coupled electron transport
Sulba_1959	COG0650	Formate hydrogenlyase subunit 4
Sulba_1960	COG4237	Hydrogenase 4 membrane
Sulba_1961	COG0651	ATP synthesis coupled electron transport
Sulba_1962	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
Sulba_1962	COG3261	NADH dehydrogenase
Sulba_1964	COG3260	NADH ubiquinone oxidoreductase 20
Sulba_1969	COG0745	RESPONSE REGULATOR receiver
Sulba_1970	COG5002	protein histidine kinase activity
Sulba_1971	COG4191	Histidine kinase
Sulba_1972	COG0693	protein deglycase activity
Sulba_1973	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Sulba_1975	COG3842	ATPase activity
Sulba_1976	COG1840	ABC-type Fe3 transport system, periplasmic component
Sulba_1978	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Sulba_1979	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Sulba_1980	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Sulba_1981	COG0602	queuosine metabolic process
Sulba_1986	COG1702	phosphate starvation-inducible protein PhoH
Sulba_1987	COG0477	Major facilitator Superfamily
Sulba_1988	COG1538	Outer membrane efflux protein
Sulba_1993	COG3787	Belongs to the UPF0306 family
Sulba_1994	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
Sulba_1995	COG1854	S-ribosylhomocysteine lyase activity
Sulba_2005	COG4773	Receptor
Sulba_2007	COG1595	DNA-templated transcription, initiation
Sulba_2008	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
Sulba_2011	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Sulba_2013	COG0546	phosphoglycolate phosphatase activity
Sulba_2015	COG2885	chlorophyll binding
Sulba_2015	COG3047	cAMP biosynthetic process
Sulba_2019	COG0038	chloride channel
Sulba_2020	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Sulba_2023	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Sulba_2024	COG1074	ATP-dependent DNA helicase activity
Sulba_2030	COG2010	Cytochrome c
Sulba_2033	COG3278	Belongs to the heme-copper respiratory oxidase family
Sulba_2035	COG0840	transmembrane signaling receptor activity
Sulba_2037	COG0505	Belongs to the CarA family
Sulba_2041	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Sulba_2042	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Sulba_2043	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Sulba_2047	COG0546	phosphoglycolate phosphatase activity
Sulba_2048	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Sulba_2051	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Sulba_2052	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Sulba_2053	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Sulba_2056	COG0203	ribosomal protein L17
Sulba_2058	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Sulba_2059	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Sulba_2060	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Sulba_2061	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Sulba_2063	COG0024	Methionine aminopeptidase
Sulba_2064	COG0201	protein transport
Sulba_2065	COG0200	Binds to the 23S rRNA
Sulba_2067	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Sulba_2068	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Sulba_2069	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Sulba_2072	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Sulba_2073	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Sulba_2074	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Sulba_2075	COG0255	Belongs to the universal ribosomal protein uL29 family
Sulba_2076	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Sulba_2077	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Sulba_2079	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Sulba_2080	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Sulba_2081	COG0089	rRNA binding
Sulba_2082	COG0088	Forms part of the polypeptide exit tunnel
Sulba_2083	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Sulba_2084	COG0051	transcription antitermination factor activity, RNA binding
Sulba_2086	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Sulba_2088	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Sulba_2089	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Sulba_2090	COG0571	ribonuclease III activity
Sulba_2091	COG0328	RNA-DNA hybrid ribonuclease activity
Sulba_2093	COG0358	DNA primase activity
Sulba_2094	COG0482	sulfurtransferase activity
Sulba_2095	COG2201	protein-glutamate methylesterase activity
Sulba_2098	COG0745	RESPONSE REGULATOR receiver
Sulba_2099	COG2205	protein histidine kinase activity
Sulba_2099	COG2198	Histidine kinase
Sulba_2099	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Sulba_2099	COG0784	Response regulator, receiver
Sulba_2100	COG2201	protein-glutamate methylesterase activity
Sulba_2101	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Sulba_2102	COG5002	protein histidine kinase activity
Sulba_2103	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Sulba_2104	COG0643	Histidine kinase
Sulba_2104	COG2198	Histidine kinase
Sulba_2106	COG0840	transmembrane signaling receptor activity
Sulba_2107	COG0835	chemotaxis
Sulba_2116	COG3328	transposase activity
Sulba_2117	COG0681	Belongs to the peptidase S26 family
Sulba_2121	COG0386	Belongs to the glutathione peroxidase family
Sulba_2126	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
Sulba_2128	COG2875	Belongs to the precorrin methyltransferase family
Sulba_2131	COG1797	cobyrinic acid a,c-diamide synthase activity
Sulba_2132	COG0778	Nitroreductase
Sulba_2133	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Sulba_2134	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Sulba_2136	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Sulba_2137	COG1492	cobalamin metabolic process
Sulba_2138	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Sulba_2141	COG1275	C4-dicarboxylate transporter malic acid transport protein
Sulba_2144	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
Sulba_2145	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
Sulba_2149	COG1280	lysine exporter protein (LysE YggA)
Sulba_2150	COG1090	epimerase
Sulba_2154	COG2962	Rard protein
Sulba_2160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Sulba_2161	COG0601	transmembrane transport
Sulba_2162	COG0747	negative chemotaxis
Sulba_2163	COG2200	EAL domain
Sulba_2165	COG1342	Belongs to the UPF0251 family
Sulba_2166	COG1968	undecaprenyl-diphosphatase activity
Sulba_2167	COG4191	Histidine kinase
Sulba_2168	COG0745	RESPONSE REGULATOR receiver
Sulba_2170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Sulba_2173	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
Sulba_2183	COG1027	Aspartate ammonia-lyase
Sulba_2184	COG1027	Aspartate ammonia-lyase
Sulba_2185	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Sulba_2186	COG0252	asparaginase activity
Sulba_2187	COG4191	Histidine kinase
Sulba_2188	COG0745	RESPONSE REGULATOR receiver
Sulba_2192	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Sulba_2193	COG0471	metal ion transport
Sulba_2194	COG0709	Synthesizes selenophosphate from selenide and ATP
Sulba_2195	COG0425	Belongs to the sulfur carrier protein TusA family
Sulba_2197	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Sulba_2198	COG0725	ABC transporter, periplasmic molybdate-binding protein
Sulba_2200	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Sulba_2202	COG0437	4 iron, 4 sulfur cluster binding
Sulba_2203	COG0243	molybdopterin cofactor binding
Sulba_2203	COG3383	formate dehydrogenase (NAD+) activity
Sulba_2207	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Sulba_2208	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Sulba_2210	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Sulba_2215	COG0437	4 iron, 4 sulfur cluster binding
Sulba_2216	COG3383	formate dehydrogenase (NAD+) activity
Sulba_2221	COG2205	protein histidine kinase activity
Sulba_2222	COG0745	RESPONSE REGULATOR receiver
Sulba_2223	COG1921	L-seryl-tRNASec selenium transferase activity
Sulba_2226	COG1053	succinate dehydrogenase
Sulba_2231	COG1053	succinate dehydrogenase
Sulba_2235	COG0745	RESPONSE REGULATOR receiver
Sulba_2236	COG2205	protein histidine kinase activity
Sulba_2238	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Sulba_2241	COG2986	histidine ammonia-lyase
Sulba_2242	COG1028	Short-chain dehydrogenase reductase Sdr
Sulba_2248	COG1131	(ABC) transporter
Sulba_2251	COG1028	Short-chain dehydrogenase reductase Sdr
Sulba_2251	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Sulba_2251	COG0318	PFAM AMP-dependent synthetase and ligase
Sulba_2251	COG0300	oxidoreductase activity
Sulba_2251	COG3321	synthase
Sulba_2262	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Sulba_2263	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Sulba_2264	COG0513	Belongs to the DEAD box helicase family
Sulba_2266	COG2608	mercury ion transmembrane transporter activity
Sulba_2267	COG1305	Transglutaminase-like
Sulba_2269	COG2205	protein histidine kinase activity
Sulba_2269	COG2202	Pas domain
Sulba_2275	COG0523	cobalamin synthesis protein
Sulba_2278	COG4191	Histidine kinase
Sulba_2279	COG0745	RESPONSE REGULATOR receiver
Sulba_2280	COG0700	Nucleoside recognition
Sulba_2281	COG3366	ferrous iron transmembrane transporter activity
Sulba_2282	COG1473	amidohydrolase
Sulba_2284	COG3290	protein histidine kinase activity
Sulba_2284	COG0840	transmembrane signaling receptor activity
Sulba_2285	COG0300	oxidoreductase activity
Sulba_2287	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Sulba_2290	COG2814	Major facilitator Superfamily
Sulba_2291	COG1238	metal cluster binding
Sulba_2293	COG1280	lysine exporter protein (LysE YggA)
Sulba_2297	COG2966	Psort location CytoplasmicMembrane, score
Sulba_2298	COG3610	response to peptide
Sulba_2303	COG0303	'Molybdopterin
Sulba_2304	COG0314	molybdopterin synthase activity
Sulba_2307	COG1104	cysteine desulfurase activity
Sulba_2308	COG1157	protein secretion by the type III secretion system
Sulba_2309	COG0302	gtp cyclohydrolase
Sulba_2310	COG0544	peptidyl-prolyl cis-trans isomerase activity
Sulba_2311	COG0740	serine-type endopeptidase activity
Sulba_2313	COG0242	peptide deformylase activity
Sulba_2315	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Sulba_2315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Sulba_2316	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Sulba_2350	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Sulba_2351	COG0732	type I restriction modification DNA specificity domain
Sulba_2354	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Sulba_2371	COG0577	efflux transmembrane transporter activity
Sulba_2371	COG1136	(ABC) transporter
Sulba_2374	COG1733	regulation of RNA biosynthetic process
Sulba_2375	COG2249	NAD(P)H dehydrogenase (quinone) activity
Sulba_2385	COG1178	ABC-type Fe3 transport system permease component
Sulba_2386	COG1840	ABC-type Fe3 transport system, periplasmic component
Sulba_2388	COG0175	sulfate reduction
Sulba_2389	COG0175	sulfate reduction
Sulba_2390	COG2895	sulfate adenylyltransferase (ATP) activity
Sulba_2392	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Sulba_2394	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Sulba_2395	COG1648	precorrin-2 dehydrogenase activity
Sulba_2395	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Sulba_2396	COG0626	cystathionine gamma-synthase activity
Sulba_2398	COG0482	sulfurtransferase activity
Sulba_2400	COG2199	diguanylate cyclase activity
Sulba_2400	COG2203	Gaf domain
Sulba_2401	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Sulba_2403	COG1538	Outer membrane efflux protein
Sulba_2411	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Sulba_2414	COG0243	molybdopterin cofactor binding
Sulba_2415	COG2204	response regulator
Sulba_2416	COG0745	RESPONSE REGULATOR receiver
Sulba_2416	COG2205	protein histidine kinase activity
Sulba_2416	COG4191	Histidine kinase
Sulba_2419	COG0243	molybdopterin cofactor binding
Sulba_2421	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Sulba_2423	COG1077	Cell shape determining protein MreB Mrl
Sulba_2424	COG0861	Integral membrane protein TerC family
Sulba_2425	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Sulba_2426	COG4303	Ethanolamine ammonia lyase large subunit
Sulba_2427	COG4302	ethanolamine ammonia-lyase activity
Sulba_2428	COG0531	amino acid
Sulba_2429	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Sulba_2430	COG0280	phosphate acetyltransferase
Sulba_2430	COG0281	malic enzyme
Sulba_2431	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Sulba_2433	COG0439	Biotin carboxylase
Sulba_2434	COG0511	ligase activity, forming carbon-carbon bonds
Sulba_2435	COG0717	Belongs to the dCTP deaminase family
Sulba_2438	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Sulba_2439	COG1073	alpha beta
Sulba_2441	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Sulba_2442	COG1086	Polysaccharide biosynthesis protein
Sulba_2443	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Sulba_2444	COG1083	cytidylyl-transferase
Sulba_2447	COG2089	acid synthase
Sulba_2450	COG0367	asparagine synthase
Sulba_2452	COG2226	methyltransferase
Sulba_2455	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Sulba_2458	COG1088	dTDP-glucose 4,6-dehydratase activity
Sulba_2462	COG0367	asparagine synthase
Sulba_2467	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Sulba_2468	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Sulba_2469	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Sulba_2470	COG0372	Belongs to the citrate synthase family
Sulba_2473	COG0148	phosphopyruvate hydratase activity
Sulba_2474	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Sulba_2475	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Sulba_2476	COG1987	bacterial-type flagellum assembly
Sulba_2477	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Sulba_2479	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Sulba_2507	COG1408	metallophosphoesterase
Sulba_2508	COG1115	amino acid carrier protein
Sulba_2509	COG2233	PERMEase
Sulba_2510	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Sulba_2511	COG0575	Belongs to the CDS family
Sulba_2514	COG1929	Belongs to the glycerate kinase type-1 family
Sulba_2515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Sulba_2517	COG3290	protein histidine kinase activity
Sulba_2517	COG0840	transmembrane signaling receptor activity
Sulba_2522	COG0450	alkyl hydroperoxide reductase
Sulba_2524	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Sulba_2525	COG0746	molybdenum cofactor guanylyltransferase activity
Sulba_2528	COG0724	RNA recognition motif
Sulba_2529	COG0315	cyclic pyranopterin monophosphate synthase activity
Sulba_2540	COG0670	Belongs to the BI1 family
Sulba_2551	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Sulba_2552	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Sulba_2554	COG0233	cytoplasmic translational termination
Sulba_2555	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Sulba_2561	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Sulba_2562	COG4786	Flagellar basal body rod
Sulba_2563	COG1749	Flagellar hook protein flgE
Sulba_2564	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
Sulba_2565	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group