locus-tag	class	description
SHALO_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
SHALO_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
SHALO_0003	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
SHALO_0004	ENOG4105BZU	Histidine kinase
SHALO_0005	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
SHALO_0008	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
SHALO_0009	ENOG4105CEN	a g-specific adenine glycosylase
SHALO_0010	ENOG4108IJ7	Glycine betaine
SHALO_0011	ENOG4108HQS	Glycine betaine
SHALO_0012	ENOG4105GIJ	Glycine betaine
SHALO_0013	ENOG4105C2C	drug resistance transporter, Bcr CflA
SHALO_0014	ENOG4106DSS	Tartrate dehydratase subunit alpha
SHALO_0015	ENOG4107GFK	fumarate
SHALO_0017	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
SHALO_0018	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
SHALO_0022	ENOG4105BZU	Histidine kinase
SHALO_0025	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_0030	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
SHALO_0031	ENOG4108MR7	Arylsulfotransferase
SHALO_0032	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_0036	ENOG4105C5I	Dehydrogenase
SHALO_0037	ENOG4108W2Y	isochorismatase
SHALO_0040	ENOG4105UEI	Transcriptional Regulator AraC Family
SHALO_0043	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
SHALO_0047	ENOG4105EZV	Transcriptional regulator
SHALO_0049	ENOG4105IPS	esterase
SHALO_0050	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
SHALO_0052	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
SHALO_0053	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SHALO_0060	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
SHALO_0061	ENOG4105MZU	cell filamentation protein
SHALO_0084	ENOG4105C01	Dihydroxy-acid dehydratase
SHALO_0085	ENOG41081FY	multiple antibiotic resistance (MarC)-related
SHALO_0087	ENOG4107SDU	Methyl-accepting chemotaxis
SHALO_0088	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
SHALO_0090	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
SHALO_0091	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
SHALO_0092	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
SHALO_0093	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
SHALO_0095	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
SHALO_0096	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
SHALO_0098	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
SHALO_0099	ENOG4107QTF	adenylosuccinate lyase
SHALO_0100	ENOG4105EI2	Pseudouridine synthase
SHALO_0101	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
SHALO_0102	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
SHALO_0104	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
SHALO_0105	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
SHALO_0106	ENOG4105CN5	Metallo-Beta-Lactamase
SHALO_0107	ENOG4105C2X	Arabinose 5-phosphate isomerase
SHALO_0108	ENOG4105FE9	pseudouridine synthase
SHALO_0109	ENOG4105D1H	recombination factor protein RarA
SHALO_0111	ENOG4105VM1	flagellar
SHALO_0113	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
SHALO_0114	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
SHALO_0115	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
SHALO_0117	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
SHALO_0122	ENOG410813J	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
SHALO_0124	ENOG4105C22	threonyL-tRNA synthetase
SHALO_0125	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
SHALO_0127	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
SHALO_0128	ENOG4105C58	cytochrome c oxidase accessory protein ccog
SHALO_0133	ENOG4106032	Glutathionylspermidine synthase
SHALO_0134	ENOG4108VPT	UPF0234 protein
SHALO_0136	ENOG41080IJ	Diacylglycerol kinase
SHALO_0142	ENOG4105BZU	Histidine kinase
SHALO_0143	ENOG4108STX	response regulator
SHALO_0146	ENOG4107PE3	Mammalian cell entry related domain protein
SHALO_0147	ENOG4105DHJ	ABC, transporter
SHALO_0148	ENOG4105CY3	ABC transporter, permease
SHALO_0150	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
SHALO_0151	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_0153	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_0158	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SHALO_0159	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
SHALO_0160	ENOG4108YZA	Nitrogen regulatory protein pii
SHALO_0162	ENOG4105CPC	Aldo Keto reductase
SHALO_0164	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SHALO_0167	ENOG4105E5Q	amino acid AbC transporter
SHALO_0168	ENOG4106PMH	Extracellular solute-binding protein family 3
SHALO_0174	ENOG4105DIK	(ABC) transporter
SHALO_0178	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
SHALO_0180	ENOG4105CEY	Amp-dependent synthetase and ligase
SHALO_0181	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
SHALO_0182	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SHALO_0183	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_0184	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SHALO_0185	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_0189	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
SHALO_0190	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_0192	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_0193	ENOG4105D65	subunit l
SHALO_0194	ENOG4105C8S	subunit m
SHALO_0195	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_0197	ENOG4105C26	Dehydrogenase
SHALO_0198	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
SHALO_0202	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_0204	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
SHALO_0205	ENOG4107TH8	cina domain protein
SHALO_0207	ENOG4107YV6	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
SHALO_0208	ENOG41082DI	50s ribosomal protein l31
SHALO_0213	ENOG4105CHM	Aminotransferase
SHALO_0214	ENOG4105D6E	homoserine dehydrogenase
SHALO_0215	ENOG41082UM	UPF0102 protein
SHALO_0217	ENOG4105C3M	thioredoxin reductase
SHALO_0218	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
SHALO_0220	ENOG4105N5T	Radical SAM Protein
SHALO_0223	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
SHALO_0225	ENOG4105CM2	brancheD-chain amino acid aminotransferase
SHALO_0227	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SHALO_0229	ENOG4105WPN	DNA integration recombination invertion protein
SHALO_0230	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
SHALO_0231	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
SHALO_0232	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
SHALO_0235	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
SHALO_0240	ENOG4105CUZ	uba thif-type nad fad binding protein
SHALO_0241	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
SHALO_0242	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
SHALO_0243	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
SHALO_0244	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
SHALO_0246	ENOG4107R88	Chemotaxis protein (CheV)
SHALO_0247	ENOG4105CBS	Chea signal transduction histidine kinase
SHALO_0248	ENOG4108V3W	Chemotaxis protein, CheW
SHALO_0250	ENOG4105EAC	phosphoserine phosphatase
SHALO_0251	ENOG4107V25	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
SHALO_0252	ENOG4105CZX	twitching motility protein
SHALO_0254	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
SHALO_0256	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
SHALO_0257	ENOG4105CQC	Prephenate dehydratase
SHALO_0258	ENOG4105CIH	Imidazole acetol-phosphate transaminase
SHALO_0259	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
SHALO_0260	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
SHALO_0265	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
SHALO_0267	ENOG4105D3R	alkyl hydroperoxide reductase
SHALO_0268	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
SHALO_0270	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
SHALO_0273	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
SHALO_0274	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
SHALO_0276	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SHALO_0277	ENOG4105C9X	ppx gppa phosphatase
SHALO_0278	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
SHALO_0280	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SHALO_0282	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
SHALO_0284	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
SHALO_0285	ENOG4105D00	flagellar biosynthetic protein flhB
SHALO_0287	ENOG4108K5P	(LipO)protein
SHALO_0288	ENOG4105VQJ	septum formation inhibitor
SHALO_0291	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
SHALO_0295	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
SHALO_0296	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
SHALO_0299	ENOG4105VEQ	Cold shock protein
SHALO_0300	ENOG4105BZU	Histidine kinase
SHALO_0303	ENOG4105NQN	cytochrome C
SHALO_0307	ENOG4107QY8	reductase
SHALO_0308	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SHALO_0309	ENOG4105DVI	reductase, NrfD
SHALO_0310	ENOG4105BZU	Histidine kinase
SHALO_0311	ENOG4108J2R	molybdopterin oxidoreductase
SHALO_0312	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SHALO_0313	ENOG4105DVI	reductase, NrfD
SHALO_0314	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SHALO_0315	ENOG4105BZU	Histidine kinase
SHALO_0317	ENOG4105CSA	Coproporphyrinogen iii oxidase
SHALO_0319	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
SHALO_0323	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
SHALO_0325	ENOG4105BZU	Histidine kinase
SHALO_0326	ENOG4105BZU	Histidine kinase
SHALO_0327	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
SHALO_0328	ENOG4105CHR	reductase
SHALO_0329	ENOG4105CF7	AraC family transcriptional regulator
SHALO_0330	ENOG4107RDF	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
SHALO_0331	ENOG4105DUM	transcriptional regulator, lysR family
SHALO_0332	ENOG4105HMI	Membrane
SHALO_0335	ENOG4108Z86	Glutamine amidotransferase
SHALO_0336	ENOG4107RNH	Outer membrane receptor FepA
SHALO_0339	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
SHALO_0346	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SHALO_0354	ENOG4108BGM	Quinol dehydrogenase periplasmic component
SHALO_0358	ENOG4105BZU	Histidine kinase
SHALO_0359	ENOG4107VQW	regulatoR
SHALO_0360	ENOG4105VBD	cytochrome C, class I
SHALO_0361	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SHALO_0362	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SHALO_0372	ENOG4108JYZ	YitT family
SHALO_0374	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
SHALO_0375	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
SHALO_0376	ENOG4105DC7	peptidase M24
SHALO_0377	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SHALO_0378	ENOG4105FZW	flagellar biosynthesis regulator FlhF
SHALO_0379	ENOG4107R21	site-determining protein
SHALO_0381	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SHALO_0382	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
SHALO_0383	ENOG4105DD5	Flagellar motor switch protein
SHALO_0384	ENOG4108URH	decarboxylase
SHALO_0386	ENOG4105CKK	Glycosyl transferase, family 2
SHALO_0388	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
SHALO_0389	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
SHALO_0392	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
SHALO_0393	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
SHALO_0394	ENOG4105MJ2	Competence protein
SHALO_0400	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SHALO_0401	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
SHALO_0404	ENOG41082XB	radical SAM domain protein
SHALO_0408	ENOG4105DFP	Integrase
SHALO_0420	ENOG4108JJA	ABC, transporter
SHALO_0421	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
SHALO_0429	ENOG4107WZZ	SMC domain protein
SHALO_0433	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
SHALO_0435	ENOG4107QRI	Phosphoketolase
SHALO_0437	ENOG4106V2I	dimethylaminohydrolase
SHALO_0438	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
SHALO_0439	ENOG4107R7Y	intracellular protease Pfpi family
SHALO_0445	ENOG4105BZU	Histidine kinase
SHALO_0448	ENOG4105K63	Thioredoxin
SHALO_0450	ENOG4105CFM	UPF0317 protein
SHALO_0455	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
SHALO_0456	ENOG4105EMU	Dehydrogenase
SHALO_0459	ENOG4105CP9	extracellular ligand-binding receptor
SHALO_0460	ENOG4105C32	Amino acid ABC transporter (Permease)
SHALO_0461	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
SHALO_0462	ENOG4105C0Z	ABC transporter
SHALO_0463	ENOG4108IV0	ABC, transporter
SHALO_0464	ENOG4105C26	Dehydrogenase
SHALO_0466	ENOG410802Z	Protein of unknown function (DUF328)
SHALO_0471	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
SHALO_0474	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
SHALO_0475	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
SHALO_0478	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
SHALO_0481	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
SHALO_0482	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
SHALO_0484	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
SHALO_0485	ENOG4108UMI	ABC transporter, permease
SHALO_0486	ENOG4105D01	(LipO)protein
SHALO_0489	ENOG4105FDR	Membrane
SHALO_0493	ENOG4108J2R	molybdopterin oxidoreductase
SHALO_0495	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SHALO_0497	ENOG4105BZU	Histidine kinase
SHALO_0498	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_0499	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
SHALO_0501	ENOG4108IEH	NADH dehydrogenase subunit g
SHALO_0502	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
SHALO_0505	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_0506	ENOG4105D65	subunit l
SHALO_0508	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_0512	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_0513	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_0514	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SHALO_0517	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
SHALO_0521	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
SHALO_0523	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
SHALO_0525	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
SHALO_0526	ENOG4105D52	delta-aminolevulinic acid dehydratase
SHALO_0527	ENOG4105DBV	ornithine carbamoyltransferase
SHALO_0528	ENOG4105T1H	UPF0763 protein
SHALO_0529	ENOG4105D4P	Coproporphyrinogen iii oxidase
SHALO_0530	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
SHALO_0535	ENOG4105K4U	addiction module toxin, RelE StbE family
SHALO_0536	ENOG4105BZU	Histidine kinase
SHALO_0538	ENOG4105K5B	UPF0225 protein
SHALO_0541	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
SHALO_0542	ENOG4108S24	Fumarate reduCtase
SHALO_0543	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
SHALO_0544	ENOG4105E33	succinate dehydrogenase
SHALO_0546	ENOG410890F	Dynamin family
SHALO_0549	ENOG4105F4G	Membrane
SHALO_0550	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
SHALO_0551	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
SHALO_0553	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
SHALO_0556	ENOG4105CE9	30S ribosomal protein S2
SHALO_0559	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
SHALO_0561	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
SHALO_0563	ENOG4105C75	arginyL-tRNA synthetase
SHALO_0565	ENOG4105BZU	Histidine kinase
SHALO_0568	ENOG4105I3K	Ferric uptake regulator, Fur family
SHALO_0569	ENOG4105CA0	peroxidase
SHALO_0573	ENOG4105CP7	Triose-phosphate isomerase
SHALO_0574	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
SHALO_0577	ENOG4105CHV	Transcription elongation factor NusA
SHALO_0579	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
SHALO_0584	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
SHALO_0585	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
SHALO_0586	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
SHALO_0587	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
SHALO_0592	ENOG4107QMP	dna polymerase iii subunits gamma and tau
SHALO_0593	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
SHALO_0594	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
SHALO_0595	ENOG4105BZU	Histidine kinase
SHALO_0596	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
SHALO_0601	ENOG4105CSR	polyphosphate kinase 2
SHALO_0603	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SHALO_0604	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SHALO_0606	ENOG4108YXA	Membrane
SHALO_0607	ENOG4105C1J	atp-dependent rna helicase
SHALO_0608	ENOG4105C6Z	Gluconate
SHALO_0609	ENOG4105DDY	UPF0142 protein ycaO
SHALO_0610	ENOG41062JF	Transcriptional regulator
SHALO_0611	ENOG4105ETP	RND efflux system, outer membrane lipoprotein
SHALO_0612	ENOG4105CW7	secretion protein, HlyD family
SHALO_0613	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
SHALO_0614	ENOG4107YZX	Universal stress protein
SHALO_0616	ENOG4105BZU	Histidine kinase
SHALO_0618	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
SHALO_0619	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
SHALO_0620	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
SHALO_0622	ENOG4105VXP	Protein of unknown function DUF86
SHALO_0635	ENOG4105C32	Amino acid ABC transporter (Permease)
SHALO_0636	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
SHALO_0637	ENOG4105C0Z	ABC transporter
SHALO_0638	ENOG4108IV0	ABC, transporter
SHALO_0639	ENOG4105CRE	cytochrome C
SHALO_0647	ENOG4105CEV	competence damage-inducible protein
SHALO_0648	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
SHALO_0650	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
SHALO_0651	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
SHALO_0652	ENOG4105DWV	Homoserine O-trans-acetylase
SHALO_0655	ENOG4105D06	uba thif-type nad fad binding protein
SHALO_0656	ENOG4105CHM	Aminotransferase
SHALO_0657	ENOG4105DFU	Cell wall formation (By similarity)
SHALO_0659	ENOG4105C98	muts2 protein
SHALO_0660	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
SHALO_0661	ENOG4105KME	endoribonuclease L-psp
SHALO_0662	ENOG4107RSR	Malate quinone oxidoreductase
SHALO_0665	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
SHALO_0666	ENOG4105CN1	protease
SHALO_0670	ENOG4105K46	50S ribosomal protein l27
SHALO_0671	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SHALO_0672	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
SHALO_0673	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
SHALO_0675	ENOG4107QJE	Chromosome Partitioning Protein
SHALO_0676	ENOG4105FA0	parb-like partition protein
SHALO_0678	ENOG4105YF2	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
SHALO_0679	ENOG4105PQH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
SHALO_0680	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
SHALO_0681	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
SHALO_0682	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
SHALO_0683	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
SHALO_0684	ENOG4105E02	MotA TolQ exbB proton channel
SHALO_0685	ENOG4105M8F	Biopolymer transport protein exbD tolR
SHALO_0687	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
SHALO_0688	ENOG4105UYK	outer membrane protein a
SHALO_0690	ENOG4108YZY	peptidylprolyl cis-trans isomerase
SHALO_0692	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
SHALO_0693	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
SHALO_0694	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
SHALO_0696	ENOG4105CBC	glutamate synthase
SHALO_0697	ENOG4105BZ8	glutamate synthase
SHALO_0699	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
SHALO_0700	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
SHALO_0701	ENOG4105SCY	DNAK suppressor
SHALO_0703	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
SHALO_0707	ENOG4105DD5	Flagellar motor switch protein
SHALO_0710	ENOG4108Z0R	Transferase
SHALO_0712	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
SHALO_0713	ENOG4108MTT	Glutamate-rich protein grpB
SHALO_0714	ENOG4108UYN	gCN5-related N-acetyltransferase
SHALO_0716	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
SHALO_0719	ENOG4105C85	amino acid
SHALO_0720	ENOG4105HF0	Membrane
SHALO_0721	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
SHALO_0722	ENOG4105CK2	sodium dicarboxylate symporter
SHALO_0723	ENOG4105CK2	sodium dicarboxylate symporter
SHALO_0725	ENOG4105C2M	dna polymerase I
SHALO_0726	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
SHALO_0728	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
SHALO_0733	ENOG4105C4M	(Ubiquinol oxidase) subunit I
SHALO_0734	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
SHALO_0735	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SHALO_0736	ENOG410804D	Sensor Signal Transduction Histidine Kinase
SHALO_0737	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
SHALO_0738	ENOG4105BZU	Histidine kinase
SHALO_0740	ENOG4105CEY	Amp-dependent synthetase and ligase
SHALO_0741	ENOG4105E2X	shikimate dehydrogenase
SHALO_0742	ENOG4105CRQ	synthase (Component I)
SHALO_0745	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
SHALO_0746	ENOG4105CRK	lysyL-tRNA synthetase
SHALO_0749	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
SHALO_0750	ENOG4105CZX	twitching motility protein
SHALO_0751	ENOG410855J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
SHALO_0753	ENOG4108TX7	
SHALO_0756	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
SHALO_0757	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_0758	ENOG4105BZU	Histidine kinase
SHALO_0761	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
SHALO_0764	ENOG4108IYU	L-aspartate oxidase
SHALO_0765	ENOG4105DN9	Na H antiporter
SHALO_0766	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
SHALO_0768	ENOG4105C12	Phosphoribosylglycinamide synthetase
SHALO_0771	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
SHALO_0778	ENOG4105K44	type iii secretion
SHALO_0790	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
SHALO_0793	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
SHALO_0794	ENOG4105D9Q	decarboxylase (Beta subunit)
SHALO_0795	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
SHALO_0796	ENOG4105CH7	arginosuccinase
SHALO_0798	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
SHALO_0799	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
SHALO_0800	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
SHALO_0801	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
SHALO_0802	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
SHALO_0804	ENOG4108JQ1	Dehydrogenase
SHALO_0806	ENOG4107KET	secretion protein, HlyD family
SHALO_0808	ENOG4105BZS	acriflavin resistance protein
SHALO_0812	ENOG4107S0N	DJ-1 family
SHALO_0813	ENOG4108QAF	Methyl-accepting chemotaxis sensory transducer
SHALO_0814	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
SHALO_0817	ENOG4105CBX	hi0933 family
SHALO_0820	ENOG4105BZU	Histidine kinase
SHALO_0821	ENOG4108YXA	Membrane
SHALO_0822	ENOG4106492	Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO (By similarity)
SHALO_0825	ENOG4105BZU	Histidine kinase
SHALO_0828	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
SHALO_0830	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
SHALO_0831	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
SHALO_0832	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
SHALO_0832	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
SHALO_0834	ENOG4105C0B	DNA polymerase III (alpha subunit)
SHALO_0836	ENOG4105BZU	Histidine kinase
SHALO_0838	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
SHALO_0839	ENOG4105C1A	potassium transporter peripheral membrane
SHALO_0842	ENOG4105CNI	cell division protein FtsW
SHALO_0843	ENOG4105C34	Pseudouridine synthase
SHALO_0845	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
SHALO_0850	ENOG410692R	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
SHALO_0851	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
SHALO_0852	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
SHALO_0853	ENOG4105EA8	2-Nitropropane dioxygenase
SHALO_0854	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
SHALO_0856	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
SHALO_0857	ENOG4105C9M	aspartyl-trna synthetase
SHALO_0858	ENOG4105BZU	Histidine kinase
SHALO_0860	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
SHALO_0861	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
SHALO_0862	ENOG4105DAA	L-lactate
SHALO_0863	ENOG4105BZU	Histidine kinase
SHALO_0864	ENOG4105F8V	Hydrolase, tatD family
SHALO_0865	ENOG41068JE	domain protein
SHALO_0866	ENOG4105K6T	rare lipoprotein A
SHALO_0867	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
SHALO_0868	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
SHALO_0871	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
SHALO_0874	ENOG4105CJN	penicillin-binding protein
SHALO_0876	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
SHALO_0878	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
SHALO_0880	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
SHALO_0885	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
SHALO_0886	ENOG4105CX6	glutaminyL-tRNA synthetase
SHALO_0889	ENOG4105WH1	Two component transcriptional regulator luxr family
SHALO_0890	ENOG4107QPK	)-transporter
SHALO_0891	ENOG4105BZU	Histidine kinase
SHALO_0892	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_0894	ENOG4108NEV	two component transcriptional regulator, LytTR family
SHALO_0895	ENOG4105RAK	Histidine kinase
SHALO_0897	ENOG4105C5Q	Transcriptional regulator
SHALO_0898	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
SHALO_0899	ENOG4105E33	succinate dehydrogenase
SHALO_0900	ENOG41086B8	CoB-CoM heterodisulfide reductase
SHALO_0902	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_0905	ENOG4108W6G	cytochrome C
SHALO_0906	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
SHALO_0907	ENOG4105CRE	cytochrome C
SHALO_0911	ENOG4105MJ9	esterase
SHALO_0917	ENOG4108C33	Resolvase
SHALO_0918	ENOG41067MG	lrgb family
SHALO_0922	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
SHALO_0924	ENOG4108N5C	SNARE associated Golgi protein-related protein
SHALO_0928	ENOG4105EMK	carboxylate amino acid amine transporter
SHALO_0930	ENOG4108CIP	transcriptional regulator
SHALO_0933	ENOG4107XVH	Transcriptional regulator
SHALO_0937	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
SHALO_0940	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
SHALO_0944	ENOG4105BZ9	Cytochrome C oxidase, subunit I
SHALO_0949	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
SHALO_0950	ENOG4108BGM	Quinol dehydrogenase periplasmic component
SHALO_0951	ENOG4105GXZ	Ferredoxin-type protein NapH
SHALO_0952	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
SHALO_0953	ENOG4108ZNS	ferredoxin-type protein NapF
SHALO_0956	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
SHALO_0957	ENOG4105C3G	gtp-binding protein
SHALO_0963	ENOG4108AEY	RNA polymerase sigma factor
SHALO_0966	ENOG4108J2R	molybdopterin oxidoreductase
SHALO_0969	ENOG4105ETX	regulatoR
SHALO_0971	ENOG4105BZU	Histidine kinase
SHALO_0972	ENOG4105VBD	cytochrome C, class I
SHALO_0973	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SHALO_0974	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SHALO_0976	ENOG4107SDU	Methyl-accepting chemotaxis
SHALO_0978	ENOG4105BZU	Histidine kinase
SHALO_0979	ENOG4105DJ4	phosphatidylserine decarboxylase
SHALO_0980	ENOG4105C1J	atp-dependent rna helicase
SHALO_0982	ENOG4105WWK	YheO domain protein
SHALO_0983	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
SHALO_0985	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
SHALO_0987	ENOG4108NIW	Leucine export protein LeuE
SHALO_0988	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_0992	ENOG4105ENE	Histidine kinase
SHALO_0994	ENOG4105EUZ	Beta-lactamase domain protein
SHALO_0995	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
SHALO_0997	ENOG4105CDY	transcriptional regulatory protein
SHALO_1002	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
SHALO_1004	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
SHALO_1005	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
SHALO_1007	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SHALO_1016	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
SHALO_1032	ENOG4108RH0	Crea protein
SHALO_1033	ENOG4105BZU	Histidine kinase
SHALO_1035	ENOG4107VQW	regulatoR
SHALO_1041	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
SHALO_1042	ENOG4108Q9V	regulatoR
SHALO_1049	ENOG41084S7	Plasmid maintenance system antidote protein
SHALO_1058	ENOG4105DWK	Membrane
SHALO_1059	ENOG4107XM3	UPF0442 protein
SHALO_1060	ENOG4105W3S	hemerythrin-like, metal-binding protein
SHALO_1061	ENOG4105C59	p-type ATPase
SHALO_1065	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
SHALO_1066	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
SHALO_1068	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
SHALO_1070	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_1071	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_1072	ENOG4107S5G	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
SHALO_1075	ENOG4108UT2	hemolysin iii
SHALO_1077	ENOG410829K	Lysine exporter protein (Lyse ygga)
SHALO_1078	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
SHALO_1079	ENOG4107QR9	Iron-sulfur cluster binding protein
SHALO_1080	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
SHALO_1081	ENOG410631K	Membrane
SHALO_1085	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
SHALO_1087	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
SHALO_1089	ENOG4105D0M	Protease HtpX homolog
SHALO_1093	ENOG4105BZU	Histidine kinase
SHALO_1094	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
SHALO_1095	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
SHALO_1096	ENOG4108VD1	dedA family
SHALO_1097	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
SHALO_1098	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
SHALO_1100	ENOG4108YZG	isomerase
SHALO_1101	ENOG4108Z4T	Peptidase M50
SHALO_1102	ENOG4105C3F	Signal peptidase i
SHALO_1103	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
SHALO_1105	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
SHALO_1108	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
SHALO_1110	ENOG4105CB5	ATP-dependent DNA helicase recG
SHALO_1116	ENOG410821Z	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
SHALO_1117	ENOG410901F	(LipO)protein
SHALO_1118	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
SHALO_1119	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
SHALO_1120	ENOG4108UUM	single-stranded DNA-binding protein
SHALO_1122	ENOG4108VMB	DNA polymerase III subunit delta'
SHALO_1123	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
SHALO_1126	ENOG4107QMS	site-determining protein
SHALO_1127	ENOG41084TB	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
SHALO_1130	ENOG4107TSN	permease
SHALO_1131	ENOG4108UIN	ybak prolyl-trna synthetase associated region
SHALO_1134	ENOG4105EJQ	L-serine dehydratase
SHALO_1135	ENOG4105GSH	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
SHALO_1136	ENOG4105EN6	Membrane
SHALO_1137	ENOG4105C8Y	Acetylornithine aminotransferase
SHALO_1139	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
SHALO_1140	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
SHALO_1141	ENOG4105X6C	Flagellar basal body-associated protein FliL
SHALO_1142	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
SHALO_1143	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
SHALO_1146	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
SHALO_1147	ENOG4105BZ1	(ABC) transporter
SHALO_1149	ENOG4108VD1	dedA family
SHALO_1151	ENOG4105C09	Bile acid
SHALO_1152	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
SHALO_1154	ENOG4105EQD	regulatoR
SHALO_1155	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_1156	ENOG4105BZU	Histidine kinase
SHALO_1157	ENOG4105BZU	Histidine kinase
SHALO_1160	ENOG4108Z66	YbaK ebsC protein
SHALO_1173	ENOG4105GR3	Histidine kinase
SHALO_1174	ENOG4107RN3	metallophosphoesterase
SHALO_1175	ENOG4108YYC	ycei family
SHALO_1178	ENOG4107XPZ	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
SHALO_1181	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
SHALO_1187	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
SHALO_1188	ENOG4107YD3	Thioesterase
SHALO_1190	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
SHALO_1193	ENOG4107S73	homocitrate synthase
SHALO_1195	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_1197	ENOG4105BZU	Histidine kinase
SHALO_1199	ENOG4108STX	response regulator
SHALO_1200	ENOG4105CNW	domain protein
SHALO_1203	ENOG4105D0B	Nitrogenase protein alpha chain
SHALO_1204	ENOG4105DK8	Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN
SHALO_1205	ENOG4108J5H	Homocysteine s-methyltransferase
SHALO_1206	ENOG4105C26	Dehydrogenase
SHALO_1207	ENOG4105EGS	Mechanosensitive ion channel
SHALO_1211	ENOG4108VQE	nitrogen fixation protein
SHALO_1213	ENOG4106C8Q	May protect the nitrogenase Fe-Mo protein from oxidative damage (By similarity)
SHALO_1214	ENOG4105XV5	nifz family
SHALO_1216	ENOG4105KXW	Ferredoxin
SHALO_1217	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SHALO_1219	ENOG4108Z7F	N-acetyltransferase
SHALO_1223	ENOG4105F5P	DNA-damage-inducible protein d
SHALO_1229	ENOG4105BZU	Histidine kinase
SHALO_1234	ENOG4108VKG	metal-dependent hydrolase
SHALO_1239	ENOG4105JAB	phenazine biosynthesis protein, phzf family
SHALO_1247	ENOG4105BZU	Histidine kinase
SHALO_1248	ENOG4105BZU	Histidine kinase
SHALO_1249	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
SHALO_1256	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_1257	ENOG4107QY8	reductase
SHALO_1259	ENOG4105BZU	Histidine kinase
SHALO_1260	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
SHALO_1261	ENOG4108RQS	Two component transcriptional regulator (Winged helix family
SHALO_1264	ENOG4105RRV	Inherit from COG: copper resistance
SHALO_1265	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
SHALO_1267	ENOG4105D0B	Nitrogenase protein alpha chain
SHALO_1268	ENOG4105CY9	nitrogenase molybdenum-iron protein beta chain
SHALO_1270	ENOG4108TQ9	Histidine kinase
SHALO_1271	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SHALO_1273	ENOG4108NEV	two component transcriptional regulator, LytTR family
SHALO_1278	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
SHALO_1279	ENOG4105JJR	Histidine kinase
SHALO_1280	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
SHALO_1290	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_1291	ENOG4105BZ8	glutamate synthase
SHALO_1292	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
SHALO_1293	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
SHALO_1294	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
SHALO_1295	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SHALO_1297	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_1303	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
SHALO_1305	ENOG4108YZY	peptidylprolyl cis-trans isomerase
SHALO_1307	ENOG4105CKI	cobalamin synthesis protein
SHALO_1308	ENOG4105VCD	cytoplasmic protein
SHALO_1309	ENOG4105D22	carbon starvation protein
SHALO_1311	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
SHALO_1312	ENOG41084IN	nitrogen fixation protein
SHALO_1318	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
SHALO_1319	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
SHALO_1321	ENOG4105BZU	Histidine kinase
SHALO_1323	ENOG4105BZU	Histidine kinase
SHALO_1327	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
SHALO_1329	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
SHALO_1331	ENOG4105DHT	Metal Dependent Phosphohydrolase
SHALO_1332	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_1333	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
SHALO_1335	ENOG4105C5H	ABC transporter
SHALO_1336	ENOG4108SEK	ompa motb domain protein
SHALO_1338	ENOG4108IG5	Transcriptional regulator
SHALO_1341	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
SHALO_1344	ENOG4108RCM	Nitroreductase
SHALO_1345	ENOG4108RCM	Nitroreductase
SHALO_1349	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
SHALO_1354	ENOG4105DZS	Phenylacetate-CoA ligase
SHALO_1361	ENOG4107TPX	flagellar hook-associated
SHALO_1364	ENOG4106H78	methyltransferase
SHALO_1365	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
SHALO_1366	ENOG4105YKR	
SHALO_1370	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
SHALO_1372	ENOG4105CHH	sulfate transporter
SHALO_1373	ENOG4105VSH	4-oxalocrotonate tautomerase
SHALO_1377	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
SHALO_1378	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
SHALO_1380	ENOG4105CD3	dihydroorotase
SHALO_1381	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
SHALO_1383	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
SHALO_1386	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
SHALO_1387	ENOG4105CN7	Flagellar biosynthetic protein FliP
SHALO_1388	ENOG4105DSB	aldose 1-epimerase
SHALO_1389	ENOG4105KVH	Transcriptional regulator
SHALO_1390	ENOG4105NF4	modulator of drug activity
SHALO_1393	ENOG4107PU6	Membrane
SHALO_1394	ENOG4105CCT	upf0313 protein
SHALO_1395	ENOG4107QP8	phosphohexose isomerase
SHALO_1399	ENOG4105DPX	Hydrogenase, large subunit
SHALO_1400	ENOG4105E3S	small subunit
SHALO_1401	ENOG4105DPX	Hydrogenase, large subunit
SHALO_1402	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
SHALO_1403	ENOG4108USZ	hydrogenase
SHALO_1404	ENOG4108P97	
SHALO_1406	ENOG4105MRR	Transcriptional regulator (By similarity)
SHALO_1407	ENOG4105E0K	tonB-dependent siderophore receptor
SHALO_1411	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
SHALO_1412	ENOG4105CQS	hydrogenase expression formation protein HypD
SHALO_1413	ENOG4105C45	hydrogenase expression formation protein (HypE)
SHALO_1415	ENOG4107TCE	N-acetyltransferase
SHALO_1416	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
SHALO_1419	ENOG4105E9K	Isocitrate dehydrogenase
SHALO_1420	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
SHALO_1421	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
SHALO_1422	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
SHALO_1424	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
SHALO_1425	ENOG4107QK6	Thiamine pyrophosphate
SHALO_1430	ENOG4105C9Q	fumarate hydratase class II
SHALO_1433	ENOG41081FY	multiple antibiotic resistance (MarC)-related
SHALO_1436	ENOG4105DFA	alanine racemase domain protein
SHALO_1437	ENOG4105DZP	Membrane-associated zinc metalloprotease
SHALO_1438	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
SHALO_1439	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
SHALO_1440	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
SHALO_1442	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
SHALO_1443	ENOG4105BZ1	(ABC) transporter
SHALO_1444	ENOG4105C8N	cysteinyl-tRNA synthetase
SHALO_1445	ENOG4105CJR	Integral membrane protein (MviN
SHALO_1447	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
SHALO_1448	ENOG4105CPF	Cell wall formation (By similarity)
SHALO_1452	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
SHALO_1453	ENOG4105C6K	Malic enzyme
SHALO_1454	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
SHALO_1459	ENOG4107QHF	type ii secretion system protein e
SHALO_1462	ENOG4105GVR	general secretion pathway protein D
SHALO_1466	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
SHALO_1467	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
SHALO_1468	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
SHALO_1471	ENOG4105CDH	Citrulline--aspartate ligase
SHALO_1472	ENOG410854I	s4 domain protein
SHALO_1473	ENOG4107QYG	anthranilate phosphoribosyltransferase
SHALO_1474	ENOG4105K8N	protein family UPF0079, ATPase
SHALO_1475	ENOG4108IUZ	ABC transporter
SHALO_1476	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SHALO_1484	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_1487	ENOG4107YTP	response regulator receiver protein
SHALO_1490	ENOG4107EFR	Flavocytochrome c
SHALO_1498	ENOG4105BZU	Histidine kinase
SHALO_1499	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_1502	ENOG4105CQZ	Histidine kinase
SHALO_1503	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
SHALO_1505	ENOG4108BGM	Quinol dehydrogenase periplasmic component
SHALO_1507	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
SHALO_1509	ENOG4108YZT	Adenosylcobinamide kinase
SHALO_1511	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
SHALO_1513	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
SHALO_1515	ENOG4107PPM	cobalt chelatase
SHALO_1516	ENOG4105EHG	Permease protein
SHALO_1517	ENOG4105E0A	ABC, transporter
SHALO_1519	ENOG41081F0	Precorrin-8x methylmutase
SHALO_1520	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
SHALO_1522	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
SHALO_1523	ENOG4105DVK	Precorrin-2 c20-methyltransferase
SHALO_1524	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
SHALO_1525	ENOG4108P62	biosynthesis protein (CbiG)
SHALO_1526	ENOG4105E4R	Precorrin-3B C17-methyltransferase
SHALO_1528	ENOG4108JTQ	reductase
SHALO_1529	ENOG4105BZ1	(ABC) transporter
SHALO_1530	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
SHALO_1532	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
SHALO_1533	ENOG4108IG5	Transcriptional regulator
SHALO_1556	ENOG410841J	DNA-binding protein Hu
SHALO_1558	ENOG4105CNU	cell division protein FtsK
SHALO_1559	ENOG4107QIJ	Aconitate hydratase 2
SHALO_1560	ENOG4108YZY	peptidylprolyl cis-trans isomerase
SHALO_1561	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
SHALO_1562	ENOG4105C6X	Major Facilitator
SHALO_1566	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
SHALO_1567	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_1568	ENOG4105K4P	CoA-binding domain protein
SHALO_1569	ENOG4105C7B	Threonine dehydratase
SHALO_1571	ENOG4105CDA	abc transporter atp-binding protein
SHALO_1572	ENOG4105DRP	amino acid AbC transporter
SHALO_1573	ENOG4105EZ7	amino acid ABC transporter
SHALO_1574	ENOG4107QXX	ABC transporter
SHALO_1575	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
SHALO_1577	ENOG4107T5V	SNARE associated Golgi
SHALO_1579	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SHALO_1580	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
SHALO_1583	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
SHALO_1584	ENOG4105QTX	Pfam:UPF0153
SHALO_1586	ENOG4105DK0	Indole-3-glycerol phosphate synthase
SHALO_1588	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
SHALO_1590	ENOG4105G01	cobalamin (vitamin B12) biosynthesis CbiM protein
SHALO_1594	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
SHALO_1595	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
SHALO_1598	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
SHALO_1601	ENOG4105C7K	acetolactate synthase
SHALO_1602	ENOG4108ZP8	Acetolactate synthase small subunit
SHALO_1603	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
SHALO_1605	ENOG4105BZ8	glutamate synthase
SHALO_1606	ENOG4105CHM	Aminotransferase
SHALO_1607	ENOG4105D0B	Nitrogenase protein alpha chain
SHALO_1608	ENOG4108JUA	Transcriptional regulator
SHALO_1610	ENOG4105CY9	nitrogenase molybdenum-iron protein beta chain
SHALO_1611	ENOG4105SJ7	Fe-only nitrogenase subunit delta
SHALO_1612	ENOG4107V0H	Nitrogenase protein alpha chain
SHALO_1613	ENOG4105D7W	serine acetyltransferase
SHALO_1614	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
SHALO_1615	ENOG4105CUT	histidyl-tRNA synthetase
SHALO_1616	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
SHALO_1617	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
SHALO_1618	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
SHALO_1622	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
SHALO_1623	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
SHALO_1628	ENOG4107QPK	)-transporter
SHALO_1630	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
SHALO_1631	ENOG4105DVM	PP-loop domain protein
SHALO_1632	ENOG4105C8M	UPF0272 protein
SHALO_1633	ENOG4105QUH	Domain of unknown function (DUF2088)
SHALO_1634	ENOG4107GFK	fumarate
SHALO_1636	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
SHALO_1637	ENOG4105BZU	Histidine kinase
SHALO_1643	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SHALO_1644	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
SHALO_1646	ENOG4105D49	3-dehydroquinate synthase
SHALO_1648	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
SHALO_1653	ENOG4105DEN	Luciferase family
SHALO_1655	ENOG4105CHR	reductase
SHALO_1657	ENOG4105D29	Helix-turn-helix type 11 domain protein
SHALO_1658	ENOG4105FE9	pseudouridine synthase
SHALO_1660	ENOG4105C7K	acetolactate synthase
SHALO_1663	ENOG4105CSV	Glutaminase
SHALO_1664	ENOG4105BZU	Histidine kinase
SHALO_1667	ENOG4107Z3H	Transcriptional regulator, TetR family
SHALO_1673	ENOG4108RAC	Rubrerythrin
SHALO_1675	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
SHALO_1676	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
SHALO_1679	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
SHALO_1680	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
SHALO_1681	ENOG4105EAH	synthase
SHALO_1686	ENOG4105C6T	cysteine synthase
SHALO_1687	ENOG4105BZU	Histidine kinase
SHALO_1688	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
SHALO_1689	ENOG4105CH5	extracellular solute-binding protein, family 7
SHALO_1690	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
SHALO_1692	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
SHALO_1694	ENOG4105D2N	Aldolase
SHALO_1695	ENOG4105EIN	peptidylprolyl cis-trans isomerase
SHALO_1698	ENOG4105CIN	aminoacyl-histidine dipeptidase
SHALO_1700	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
SHALO_1703	ENOG4105C4K	Nad synthetase
SHALO_1704	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
SHALO_1706	ENOG4105CAS	nag kinase
SHALO_1707	ENOG4107QID	Threonine synthase
SHALO_1708	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
SHALO_1711	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
SHALO_1712	ENOG4105CSR	polyphosphate kinase 2
SHALO_1713	ENOG4105CFG	Acts as a chaperone (By similarity)
SHALO_1714	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SHALO_1715	ENOG4108122	heat-inducible transcription repressor
SHALO_1718	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
SHALO_1719	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
SHALO_1720	ENOG4105D7B	Flagellar biosynthesis protein flha
SHALO_1721	ENOG4108KA0	Inherit from COG: Phosphoesterase, DHHA1
SHALO_1723	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
SHALO_1724	ENOG4106TD9	Diguanylate cyclase
SHALO_1725	ENOG4105DTN	riboflavin biosynthesis protein ribF
SHALO_1726	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
SHALO_1727	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
SHALO_1728	ENOG4105EJ9	Membrane
SHALO_1730	ENOG4105EEI	dihydropteroate synthase
SHALO_1733	ENOG4105CFH	Aspartokinase
SHALO_1734	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
SHALO_1735	ENOG4105CSA	Coproporphyrinogen iii oxidase
SHALO_1736	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
SHALO_1737	ENOG4105KNI	merR family transcriptional Regulator
SHALO_1738	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
SHALO_1739	ENOG4105C0H	protease
SHALO_1740	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SHALO_1741	ENOG4105BZU	Histidine kinase
SHALO_1744	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
SHALO_1746	ENOG4105BZU	Histidine kinase
SHALO_1747	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
SHALO_1748	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
SHALO_1750	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
SHALO_1751	ENOG4108512	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
SHALO_1754	ENOG4105DJI	Methylaspartate mutase, E subunit
SHALO_1757	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
SHALO_1760	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
SHALO_1761	ENOG4105CN1	protease
SHALO_1763	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
SHALO_1764	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
SHALO_1766	ENOG4105E9Q	Acyl-transferase
SHALO_1767	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
SHALO_1769	ENOG4105C7Z	Conserved Protein
SHALO_1770	ENOG41085GJ	domain protein
SHALO_1778	ENOG4107QUV	Domain protein
SHALO_1782	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
SHALO_1786	ENOG4105DHT	Metal Dependent Phosphohydrolase
SHALO_1787	ENOG4105CGY	Dna recombination protein
SHALO_1789	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
SHALO_1791	ENOG4105EIN	peptidylprolyl cis-trans isomerase
SHALO_1792	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
SHALO_1793	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
SHALO_1796	ENOG4105D0M	Protease HtpX homolog
SHALO_1798	ENOG4105C5H	ABC transporter
SHALO_1799	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_1801	ENOG4105VG1	fes assembly suf system protein
SHALO_1804	ENOG4105DFH	Transport of potassium into the cell (By similarity)
SHALO_1805	ENOG4105DC1	bifunctional purine biosynthesis protein purh
SHALO_1806	ENOG4105KVY	Required for disulfide bond formation in some proteins (By similarity)
SHALO_1809	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
SHALO_1810	ENOG4105C87	Aminotransferase class I and II
SHALO_1814	ENOG4108R5S	membrane
SHALO_1815	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
SHALO_1816	ENOG4105BZU	Histidine kinase
SHALO_1818	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
SHALO_1819	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
SHALO_1820	ENOG4105D5K	Hemolysin activator protein
SHALO_1821	ENOG4105CKT	filamentous hemagglutinin
SHALO_1821	ENOG4105CKT	filamentous hemagglutinin
SHALO_1834	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_1835	ENOG4105BZU	Histidine kinase
SHALO_1836	ENOG4105CY0	Metallo-Beta-Lactamase
SHALO_1837	ENOG4108IQE	Amp-dependent synthetase and ligase
SHALO_1839	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
SHALO_1840	ENOG4105C08	Histidine kinase
SHALO_1841	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
SHALO_1842	ENOG4105CZN	Potassium uptake protein
SHALO_1843	ENOG4107ZYR	domain protein
SHALO_1844	ENOG4105E0X	reductase
SHALO_1847	ENOG4105MFX	4-diphosphocytidyl-2c-methyl-d-erythritol synthase
SHALO_1848	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
SHALO_1849	ENOG4105DZS	Phenylacetate-CoA ligase
SHALO_1850	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
SHALO_1852	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
SHALO_1856	ENOG4105BZU	Histidine kinase
SHALO_1859	ENOG4105DS1	cytochrome b561
SHALO_1862	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SHALO_1864	ENOG4105PGM	cation diffusion facilitator family transporter
SHALO_1868	ENOG4108ESX	Receptor
SHALO_1870	ENOG4105D64	Mechanosensitive ion channel
SHALO_1877	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
SHALO_1881	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
SHALO_1882	ENOG4108NIW	Leucine export protein LeuE
SHALO_1883	ENOG4108594	Permease of the drug metabolite transporter
SHALO_1885	ENOG4105BZU	Histidine kinase
SHALO_1886	ENOG4108YZA	Nitrogen regulatory protein pii
SHALO_1889	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_1894	ENOG4105NBK	UPF0345 protein
SHALO_1895	ENOG4105BZU	Histidine kinase
SHALO_1896	ENOG4105CBX	hi0933 family
SHALO_1898	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
SHALO_1899	ENOG4105CIY	formyltetrahydrofolate deformylase
SHALO_1900	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
SHALO_1903	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
SHALO_1904	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
SHALO_1905	ENOG4105DKW	ABC transporter
SHALO_1910	ENOG4105CGK	Exodeoxyribonuclease III
SHALO_1914	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
SHALO_1915	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
SHALO_1917	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_1919	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
SHALO_1920	ENOG4108U5N	UPF0316 protein
SHALO_1922	ENOG4105BZU	Histidine kinase
SHALO_1925	ENOG4105C9U	ATP-dependent DNA helicase RecQ
SHALO_1928	ENOG4105C1J	atp-dependent rna helicase
SHALO_1930	ENOG4105BZU	Histidine kinase
SHALO_1932	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
SHALO_1938	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
SHALO_1939	ENOG4105CR4	methylisocitrate lyase
SHALO_1940	ENOG4105BZN	citrate synthase
SHALO_1941	ENOG4105DXD	2-methylcitrate dehydratase
SHALO_1943	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
SHALO_1945	ENOG4108UMN	azlc family
SHALO_1947	ENOG4105CGA	flagellar basal-body rod protein FlgG
SHALO_1948	ENOG4105CGA	flagellar basal-body rod protein FlgG
SHALO_1949	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SHALO_1951	ENOG4105KVH	Transcriptional regulator
SHALO_1955	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
SHALO_1956	ENOG4107QN1	sodium solute
SHALO_1957	ENOG41062QD	Membrane
SHALO_1958	ENOG4108STX	response regulator
SHALO_1960	ENOG4105DWY	Agmatine deiminase
SHALO_1962	ENOG4105CE1	Ferrous iron transport protein b
SHALO_1963	ENOG4107K9B	ferrous iron transport protein
SHALO_1968	ENOG4105X1Q	TOBE domain protein
SHALO_1969	ENOG4107VIJ	nudix hydrolase
SHALO_1970	ENOG4105D7N	magnesium and cobalt transport protein CorA
SHALO_1971	ENOG4105DR5	peptidase
SHALO_1973	ENOG4105CQB	FAD linked oxidase domain protein
SHALO_1974	ENOG4107S2Z	UPF0761 membrane protein
SHALO_1977	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
SHALO_1978	ENOG4105C25	Primosomal protein n'
SHALO_1979	ENOG4108VAU	general secretion pathway protein G
SHALO_1983	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
SHALO_1985	ENOG4108Z0R	Transferase
SHALO_1986	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
SHALO_1987	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
SHALO_1988	ENOG4105DJV	ribulose-phosphate 3-epimerase
SHALO_1989	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
SHALO_1992	ENOG4105D48	metallophosphoesterase
SHALO_1993	ENOG4108JA2	transcriptioN-repair coupling factor
SHALO_1995	ENOG4105DR5	peptidase
SHALO_1996	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
SHALO_1997	ENOG4105BZU	Histidine kinase
SHALO_1999	ENOG4105C8T	Leucyl-tRNA synthetase
SHALO_2000	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
SHALO_2001	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
SHALO_2002	ENOG4105VIE	preprotein translocase, subunit YajC
SHALO_2003	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
SHALO_2004	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
SHALO_2006	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
SHALO_2007	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
SHALO_2008	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
SHALO_2011	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
SHALO_2012	ENOG41085EF	Carbon storage regulator
SHALO_2013	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
SHALO_2014	ENOG4105C4R	Atp-dependent dna helicase
SHALO_2015	ENOG4105DUM	transcriptional regulator, lysR family
SHALO_2019	ENOG4105CRQ	synthase (Component I)
SHALO_2020	ENOG4105CXT	aspartate transcarbamylase
SHALO_2022	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
SHALO_2029	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
SHALO_2030	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
SHALO_2031	ENOG4105V3S	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
SHALO_2032	ENOG4105VB6	UPF0109 protein
SHALO_2034	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SHALO_2035	ENOG4105EI2	Pseudouridine synthase
SHALO_2036	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
SHALO_2038	ENOG4105EGD	dinuclear metal center protein, YbgI family
SHALO_2039	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
SHALO_2041	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
SHALO_2042	ENOG4105CFP	Peptidase U32
SHALO_2044	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
SHALO_2045	ENOG4105C5F	glutamine synthetase
SHALO_2046	ENOG4108JQC	penicillin-binding protein 1A
SHALO_2048	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
SHALO_2049	ENOG4107YJQ	MAF-like protein
SHALO_2051	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
SHALO_2053	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
SHALO_2054	ENOG4105BZU	Histidine kinase
SHALO_2055	ENOG4107QY8	reductase
SHALO_2056	ENOG4105QAX	Iron-sulfur
SHALO_2058	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
SHALO_2062	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
SHALO_2064	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
SHALO_2067	ENOG4108ZC9	flagellar basal-body rod protein flgc
SHALO_2068	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
SHALO_2069	ENOG4105CNI	cell division protein FtsW
SHALO_2073	ENOG4105HKU	nucleoside recognition domain-containing protein
SHALO_2075	ENOG4108TVT	permease
SHALO_2085	ENOG4105DDQ	anthranilate synthase
SHALO_2086	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
SHALO_2087	ENOG4105CEY	Amp-dependent synthetase and ligase
SHALO_2088	ENOG41082BM	Transcriptional regulator, arsr family
SHALO_2091	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
SHALO_2092	ENOG4105CHY	citrate lyase, alpha
SHALO_2093	ENOG4105CI0	Citrate lyase
SHALO_2095	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
SHALO_2096	ENOG4108KK1	membrane protein AbrB duplication
SHALO_2098	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
SHALO_2099	ENOG4108MRH	transcriptional regulatory protein
SHALO_2103	ENOG4105BZU	Histidine kinase
SHALO_2104	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_2105	ENOG4105D94	Major Facilitator Superfamily
SHALO_2106	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
SHALO_2107	ENOG4105C7N	Xanthine uracil vitamin C permease
SHALO_2108	ENOG4105DVY	radical SAM domain protein
SHALO_2111	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
SHALO_2113	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
SHALO_2114	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
SHALO_2117	ENOG4105BZU	Histidine kinase
SHALO_2123	ENOG4105EYW	Ion transport protein
SHALO_2127	ENOG4105C5H	ABC transporter
SHALO_2128	ENOG4105BZU	Histidine kinase
SHALO_2129	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
SHALO_2134	ENOG4107TDF	Formate hydrogenlyase subunit 4
SHALO_2135	ENOG4107WQX	hydrogenase 4 membrane subunit
SHALO_2136	ENOG4108JPZ	Monovalent cation H antiporter subunit D
SHALO_2137	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_2139	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
SHALO_2144	ENOG4105C22	threonyL-tRNA synthetase
SHALO_2146	ENOG4105CUZ	uba thif-type nad fad binding protein
SHALO_2147	ENOG4105BZU	Histidine kinase
SHALO_2150	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
SHALO_2151	ENOG4105D1F	ATP-binding protein
SHALO_2152	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
SHALO_2157	ENOG4108YYC	ycei family
SHALO_2158	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
SHALO_2159	ENOG4108PQF	modD protein
SHALO_2160	ENOG4105E0C	molybdate abc transporter
SHALO_2162	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
SHALO_2163	ENOG4105E0C	molybdate abc transporter
SHALO_2165	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
SHALO_2166	ENOG4105F4R	Transcriptional regulator mode
SHALO_2167	ENOG4105DZ1	carboxypeptidase
SHALO_2168	ENOG4105II7	pyrroline-5-carboxylate reductase
SHALO_2169	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SHALO_2170	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SHALO_2171	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
SHALO_2172	ENOG4105DFG	type I secretion outer membrane protein
SHALO_2188	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
SHALO_2189	ENOG4105M7K	Involved in the transcription termination process (By similarity)
SHALO_2190	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
SHALO_2192	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
SHALO_2193	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
SHALO_2194	ENOG4105DJP	Membrane
SHALO_2195	ENOG4105D64	Mechanosensitive ion channel
SHALO_2196	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
SHALO_2197	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
SHALO_2198	ENOG4105C31	Tryptophanyl-tRNA synthetase
SHALO_2199	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
SHALO_2201	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
SHALO_2202	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
SHALO_2204	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
SHALO_2205	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
SHALO_2207	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
SHALO_2208	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
SHALO_2210	ENOG4107ZAZ	Oligosaccharyl transferase, STT3 subunit
SHALO_2211	ENOG4105C5E	polysaccharide biosynthesis protein
SHALO_2212	ENOG4105ESV	Glycosyl transferase, family 4
SHALO_2215	ENOG4108UW5	maltose o-acetyltransferase
SHALO_2218	ENOG4107XZA	Glycosyl transferase family 2
SHALO_2220	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
SHALO_2221	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
SHALO_2222	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
SHALO_2223	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
SHALO_2225	ENOG4105C7K	acetolactate synthase
SHALO_2226	ENOG4105FAW	cDP-glucose 4,6-dehydratase
SHALO_2227	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
SHALO_2228	ENOG4105C30	Nad-dependent epimerase dehydratase
SHALO_2230	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
SHALO_2234	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
SHALO_2235	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
SHALO_2236	ENOG4107QKV	phosphomannomutase
SHALO_2246	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
SHALO_2247	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
SHALO_2248	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
SHALO_2252	ENOG4105C59	p-type ATPase
SHALO_2253	ENOG4105BZU	Histidine kinase
SHALO_2254	ENOG4105T38	integral membrane protein
SHALO_2255	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_2256	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
SHALO_2258	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
SHALO_2259	ENOG4108R6K	riboflavin synthase, subunit alpha
SHALO_2260	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_2261	ENOG4107R7A	Allophanate hydrolase subunit 2
SHALO_2263	ENOG4105E7W	lamb ycsf family protein
SHALO_2264	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
SHALO_2267	ENOG4107YTP	response regulator receiver protein
SHALO_2268	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
SHALO_2269	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
SHALO_2270	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SHALO_2271	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SHALO_2274	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
SHALO_2275	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
SHALO_2276	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
SHALO_2277	ENOG4105CHR	reductase
SHALO_2278	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
SHALO_2280	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
SHALO_2282	ENOG4105D3Q	Sugar transferase
SHALO_2288	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
SHALO_2289	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
SHALO_2290	ENOG4105CMR	udp-glucose 4-epimerase
SHALO_2291	ENOG4105DB1	molybdopterin oxidoreductase
SHALO_2293	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SHALO_2294	ENOG4105BZU	Histidine kinase
SHALO_2295	ENOG4105ETX	regulatoR
SHALO_2296	ENOG4108KCW	iron-sulfur cluster binding
SHALO_2298	ENOG4108M8H	domain protein
SHALO_2302	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
SHALO_2305	ENOG4105CJ3	phosphate transporter
SHALO_2306	ENOG4105C1J	atp-dependent rna helicase
SHALO_2307	ENOG4108UPT	UPF0178 protein
SHALO_2311	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
SHALO_2312	ENOG4107R4J	Chloride channel
SHALO_2314	ENOG4107QW4	alcohol dehydrogenase
SHALO_2317	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
SHALO_2320	ENOG4105CDV	Ompa motb domain protein
SHALO_2323	ENOG4107XGZ	Hydrolase
SHALO_2324	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
SHALO_2325	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
SHALO_2330	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
SHALO_2331	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
SHALO_2332	ENOG4108ZPB	UPF0306 protein
SHALO_2335	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
SHALO_2336	ENOG4105BZS	acriflavin resistance protein
SHALO_2347	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
SHALO_2348	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
SHALO_2350	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
SHALO_2351	ENOG4105KVH	Transcriptional regulator
SHALO_2354	ENOG4105NAU	thioesterase Superfamily protein
SHALO_2355	ENOG4105BZU	Histidine kinase
SHALO_2356	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SHALO_2360	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_2361	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
SHALO_2362	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_2363	ENOG4105PWN	phosphate abc transporter
SHALO_2364	ENOG4105C8U	phosphate abc transporter
SHALO_2366	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
SHALO_2369	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_2373	ENOG4107EFR	Flavocytochrome c
SHALO_2376	ENOG4105R48	this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase
SHALO_2378	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
SHALO_2387	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
SHALO_2388	ENOG4108PYU	two-component system response regulator
SHALO_2391	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
SHALO_2395	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
SHALO_2396	ENOG4105CYE	ATP phosphoribosyltransferase regulatory subunit
SHALO_2397	ENOG4107UUH	Aminotransferase
SHALO_2398	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_2399	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_2400	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
SHALO_2401	ENOG4105CV1	Transketolase (EC 2.2.1.1)
SHALO_2404	ENOG41084FT	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
SHALO_2405	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
SHALO_2406	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
SHALO_2409	ENOG4108ZT0	50S ribosomal protein l17
SHALO_2410	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
SHALO_2412	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
SHALO_2413	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SHALO_2414	ENOG41067V7	50S ribosomal protein L36
SHALO_2415	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
SHALO_2416	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
SHALO_2417	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
SHALO_2418	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
SHALO_2420	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
SHALO_2422	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
SHALO_2423	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
SHALO_2424	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SHALO_2426	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
SHALO_2427	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
SHALO_2428	ENOG41084HJ	50s ribosomal protein l29
SHALO_2430	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
SHALO_2431	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
SHALO_2432	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
SHALO_2435	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
SHALO_2436	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
SHALO_2440	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
SHALO_2441	ENOG4107SJW	iron permease, FTR1
SHALO_2446	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SHALO_2450	ENOG4105CE1	Ferrous iron transport protein b
SHALO_2451	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
SHALO_2452	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
SHALO_2453	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
SHALO_2455	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
SHALO_2456	ENOG4105CDH	Citrulline--aspartate ligase
SHALO_2459	ENOG4105BZU	Histidine kinase
SHALO_2460	ENOG4108UNF	response regulator
SHALO_2461	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
SHALO_2462	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
SHALO_2463	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
SHALO_2464	ENOG4105E0F	Histidine kinase
SHALO_2465	ENOG4105BZU	Histidine kinase
SHALO_2466	ENOG4105CBS	Chea signal transduction histidine kinase
SHALO_2468	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_2469	ENOG4108V3W	Chemotaxis protein, CheW
SHALO_2470	ENOG4108VYJ	response regulator receiver protein
SHALO_2475	ENOG4105CGH	5'-nucleotidase
SHALO_2477	ENOG41088H4	Diheme cytochrome SoxA (Sulfur oxidation)
SHALO_2486	ENOG4107QIV	Cytochrome c biogenesis protein
SHALO_2499	ENOG4105PV3	Inner membrane protein yqiJ
SHALO_2500	ENOG4107S78	Band 7 protein
SHALO_2515	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
SHALO_2516	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
SHALO_2519	ENOG4105CE1	Ferrous iron transport protein b
SHALO_2520	ENOG4105XFK	Ferrous iron transport protein A
SHALO_2522	ENOG4105CNM	Receptor
SHALO_2525	ENOG4105E93	esterase
SHALO_2526	ENOG4108ESX	Receptor
SHALO_2528	ENOG4105M15	transport protein ExbD
SHALO_2529	ENOG4105M8K	biopolymer transport protein
SHALO_2530	ENOG4105PGM	cation diffusion facilitator family transporter
SHALO_2531	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
SHALO_2534	ENOG4105BZ1	(ABC) transporter
SHALO_2536	ENOG4107ZSV	Receptor
SHALO_2537	ENOG4107ZSV	Receptor
SHALO_2538	ENOG4105UEI	Transcriptional Regulator AraC Family
SHALO_2540	ENOG4105BZU	Histidine kinase
SHALO_2545	ENOG4105D5T	phosphonate abc transporter
SHALO_2548	ENOG4105PAD	Hydrolase
SHALO_2549	ENOG4105KK4	UPF0060 membrane protein
SHALO_2551	ENOG4105D7X	high-affinity nickel-transporter
SHALO_2552	ENOG4105D7X	high-affinity nickel-transporter
SHALO_2556	ENOG4105N14	lysine exporter protein LysE YggA
SHALO_2557	ENOG4105ECP	epimerase
SHALO_2560	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SHALO_2563	ENOG410829K	Lysine exporter protein (Lyse ygga)
SHALO_2565	ENOG4105BZU	Histidine kinase
SHALO_2566	ENOG4105FR1	rard protein
SHALO_2568	ENOG4105DHQ	Histidine kinase
SHALO_2569	ENOG4105DIJ	Phosphoethanolamine transferase
SHALO_2571	ENOG4107XTP	(EAL) domain protein
SHALO_2574	ENOG4105BZU	Histidine kinase
SHALO_2577	ENOG4107SDU	Methyl-accepting chemotaxis
SHALO_2579	ENOG4105VYW	UPF0251 protein
SHALO_2580	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
SHALO_2581	ENOG4105CXK	mandelate racemase muconate lactonizing
SHALO_2582	ENOG4105D01	(LipO)protein
SHALO_2584	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
SHALO_2585	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
SHALO_2586	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
SHALO_2595	ENOG4105RQ9	TPR repeat-containing protein
SHALO_2599	ENOG4105S10	periplasmic binding protein
SHALO_2600	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
SHALO_2602	ENOG4108IJ0	Aspartate ammonia-lyase
SHALO_2603	ENOG4108IJ0	Aspartate ammonia-lyase
SHALO_2604	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
SHALO_2605	ENOG4105HDK	L-asparaginase
SHALO_2607	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
SHALO_2609	ENOG4105EAB	amino acid AbC transporter
SHALO_2610	ENOG4105E5Q	amino acid AbC transporter
SHALO_2613	ENOG4107R3N	Filamentation induced by cAMP protein fic
SHALO_2621	ENOG4105CRE	cytochrome C
SHALO_2622	ENOG4105DVI	reductase, NrfD
SHALO_2623	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SHALO_2624	ENOG4108V1T	peptidylprolyl cis-trans isomerase
SHALO_2625	ENOG4105V2T	cytochrome C
SHALO_2626	ENOG4105BZU	Histidine kinase
SHALO_2627	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SHALO_2628	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_2630	ENOG4105KVH	Transcriptional regulator
SHALO_2631	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
SHALO_2632	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
SHALO_2637	ENOG4105M15	transport protein ExbD
SHALO_2638	ENOG4105M8K	biopolymer transport protein
SHALO_2639	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
SHALO_2640	ENOG4105VFE	sira family
SHALO_2642	ENOG4106TNF	Periplasmic binding protein
SHALO_2644	ENOG4105BZU	Histidine kinase
SHALO_2646	ENOG4105DXB	Major Facilitator superfamily
SHALO_2651	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
SHALO_2652	ENOG4105C8W	ABC transporter
SHALO_2654	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
SHALO_2656	ENOG4105QAX	Iron-sulfur
SHALO_2661	ENOG4105E0A	ABC, transporter
SHALO_2662	ENOG4105EHG	Permease protein
SHALO_2663	ENOG4105S10	periplasmic binding protein
SHALO_2667	ENOG4105M15	transport protein ExbD
SHALO_2668	ENOG4105M8K	biopolymer transport protein
SHALO_2669	ENOG4105F4R	Transcriptional regulator mode
SHALO_2672	ENOG4105S10	periplasmic binding protein
SHALO_2674	ENOG4108BSC	Methyltransferase
SHALO_2676	ENOG4105WMR	Protein CrcB homolog
SHALO_2681	ENOG4105ID8	Transcriptional regulator, ARAC family
SHALO_2683	ENOG4105QAX	Iron-sulfur
SHALO_2689	ENOG4105BZU	Histidine kinase
SHALO_2690	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
SHALO_2691	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
SHALO_2692	ENOG4105EM7	Selenocysteine-specific translation elongation factor
SHALO_2693	ENOG41086B8	CoB-CoM heterodisulfide reductase
SHALO_2694	ENOG4105E33	succinate dehydrogenase
SHALO_2695	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
SHALO_2697	ENOG4105GVJ	transcriptional regulator
SHALO_2699	ENOG4105C2I	pirin domain protein
SHALO_2706	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SHALO_2707	ENOG4105BZU	Histidine kinase
SHALO_2713	ENOG4105C84	Histidine ammonia-lyase
SHALO_2714	ENOG4105CHR	reductase
SHALO_2718	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
SHALO_2726	ENOG4105C1J	atp-dependent rna helicase
SHALO_2729	ENOG410829K	Lysine exporter protein (Lyse ygga)
SHALO_2733	ENOG4108KS2	transglutaminase domain protein
SHALO_2735	ENOG4105DVP	Adenine-specific
SHALO_2739	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
SHALO_2741	ENOG4105EIG	urea carboxylase-associated protein 1
SHALO_2742	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
SHALO_2743	ENOG4108UMI	ABC transporter, permease
SHALO_2745	ENOG4105BZU	Histidine kinase
SHALO_2751	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
SHALO_2752	ENOG4105C08	Histidine kinase
SHALO_2753	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
SHALO_2754	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
SHALO_2755	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
SHALO_2756	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
SHALO_2758	ENOG4108NVR	Methyl-accepting chemotaxis
SHALO_2759	ENOG4105E1F	short-chain dehydrogenase reductase
SHALO_2762	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
SHALO_2763	ENOG4105CA3	membrane-bound lytic murein transglycosylase
SHALO_2765	ENOG4107RDB	Major Facilitator
SHALO_2766	ENOG4105W39	Membrane
SHALO_2770	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
SHALO_2771	ENOG4108ZEX	molybdopterin converting factor, subunit 2
SHALO_2773	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
SHALO_2774	ENOG4105C3J	Cysteine desulfurase
SHALO_2775	ENOG4108JIR	Flagellum-specific ATP synthase
SHALO_2776	ENOG4105EUJ	GTP cyclohydrolase i
SHALO_2778	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
SHALO_2781	ENOG4105C0P	Mg chelatase subunit ChlI
SHALO_2782	ENOG4108ENG	carbohydrate kinase, YjeF related protein
SHALO_2784	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
SHALO_2795	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
SHALO_2797	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SHALO_2798	ENOG4107QY8	reductase
SHALO_2803	ENOG4105BZU	Histidine kinase
SHALO_2805	ENOG4105C26	Dehydrogenase
SHALO_2808	ENOG4108JQ1	Dehydrogenase
SHALO_2812	ENOG41061MD	high-affinity nickel-transporter
SHALO_2816	ENOG4108DBC	nitroreductase
SHALO_2818	ENOG4107QPK	)-transporter
SHALO_2819	ENOG4108M3J	Dehydrogenase
SHALO_2821	ENOG4107QWP	ABC-2 type transporter
SHALO_2822	ENOG4107QWP	ABC-2 type transporter
SHALO_2823	ENOG4105CJ1	ABC, transporter
SHALO_2825	ENOG4107MVR	Transcriptional regulator
SHALO_2831	ENOG4107EFR	Flavocytochrome c
SHALO_2836	ENOG4108HYG	acetyltransferase
SHALO_2837	ENOG4108YYH	Nadph-dependent fmn reductase
SHALO_2839	ENOG4108IJF	Heavy metal efflux pump, CzcA
SHALO_2840	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
SHALO_2844	ENOG4108STX	response regulator
SHALO_2845	ENOG4105BZU	Histidine kinase
SHALO_2846	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
SHALO_2847	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
SHALO_2849	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
SHALO_2851	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
SHALO_2852	ENOG4105C11	sulfate adenylyltransferase), subunit 2
SHALO_2853	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
SHALO_2855	ENOG4105D06	uba thif-type nad fad binding protein
SHALO_2857	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
SHALO_2858	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
SHALO_2859	ENOG4108IQK	o-acetylhomoserine
SHALO_2861	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
SHALO_2865	ENOG4105GR3	Histidine kinase
SHALO_2867	ENOG4105BZU	Histidine kinase
SHALO_2872	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
SHALO_2873	ENOG4108UXE	Protein tyrosine phosphatase
SHALO_2874	ENOG4107R5R	arsenical pump membrane protein
SHALO_2875	ENOG4108UXE	Protein tyrosine phosphatase
SHALO_2877	ENOG4108K28	Arsenite oxidase, large subunit
SHALO_2880	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SHALO_2881	ENOG4105C19	ABC transporter
SHALO_2883	ENOG4105BZU	Histidine kinase
SHALO_2886	ENOG4105C3J	Cysteine desulfurase
SHALO_2887	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SHALO_2888	ENOG4105CVA	phosphate
SHALO_2889	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_2891	ENOG4105EE5	Membrane protein terC
SHALO_2892	ENOG4108XUR	Pfam:DUF178
SHALO_2893	ENOG4105D82	Glutamate dehydrogenase
SHALO_2894	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
SHALO_2895	ENOG4105C6K	Malic enzyme
SHALO_2896	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
SHALO_2898	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
SHALO_2899	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
SHALO_2900	ENOG4105DHP	deoxycytidine triphosphate deaminase
SHALO_2903	ENOG4105DR4	Methyltransferase
SHALO_2906	ENOG4105I03	Flagellin
SHALO_2907	ENOG4105C5E	polysaccharide biosynthesis protein
SHALO_2908	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
SHALO_2909	ENOG4105F0R	Cytidylyltransferase
SHALO_2910	ENOG4107DKY	pseudaminic acid biosynthesis-associated protein PseG
SHALO_2916	ENOG4105CAQ	asparagine synthetase
SHALO_2920	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
SHALO_2928	ENOG4105I03	Flagellin
SHALO_2929	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
SHALO_2930	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
SHALO_2931	ENOG4105BZN	citrate synthase
SHALO_2934	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
SHALO_2935	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
SHALO_2936	ENOG4105E63	Pfam:DUF178
SHALO_2937	ENOG4105VS8	Flagellar biosynthetic protein fliq
SHALO_2938	ENOG4105D4A	Cell wall formation (By similarity)
SHALO_2939	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
SHALO_2941	ENOG4105BZU	Histidine kinase
SHALO_2945	ENOG4105DIN	metallophosphoesterase
SHALO_2946	ENOG4105BZG	amino acid carrier protein
SHALO_2947	ENOG4105C2W	permease
SHALO_2948	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
SHALO_2949	ENOG4105KNE	Phosphatidate cytidylyltransferase
SHALO_2951	ENOG4105F23	Fibronectin-binding protein
SHALO_2952	ENOG4105BZW	Glycerate kinase
SHALO_2953	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
SHALO_2958	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
SHALO_2960	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
SHALO_2961	ENOG41080AZ	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
SHALO_2966	ENOG4105HDD	phospholipase
SHALO_2967	ENOG4105VFU	Rna-binding protein
SHALO_2968	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
SHALO_2979	ENOG4105KHC	sulfurtransferase
SHALO_2981	ENOG4105D1F	ATP-binding protein
SHALO_2990	ENOG4105HFZ	Membrane
SHALO_2993	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SHALO_2994	ENOG4108J2R	molybdopterin oxidoreductase
SHALO_2996	ENOG4105DUM	transcriptional regulator, lysR family
SHALO_3000	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SHALO_3001	ENOG4107QY8	reductase
SHALO_3002	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
SHALO_3003	ENOG4105F8J	Adenylate Guanylate cyclase
SHALO_3004	ENOG4105DHT	Metal Dependent Phosphohydrolase
SHALO_3005	ENOG4105NU9	Preprotein translocase subunit SecG
SHALO_3007	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
SHALO_3008	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
SHALO_3013	ENOG4108V0P	LemA family
SHALO_3014	ENOG4105CI3	gtp-binding protein typa
SHALO_3017	ENOG4108JQA	flagellar
SHALO_3018	ENOG4105BZE	flagellar hook protein, FlgE
SHALO_3021	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
SHALO_3022	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)