locus-tag	class	description
SMUL_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
SMUL_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
SMUL_0003	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
SMUL_0004	ENOG4105BZU	Histidine kinase
SMUL_0005	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
SMUL_0008	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
SMUL_0010	ENOG4105CEN	a g-specific adenine glycosylase
SMUL_0011	ENOG4108IJ7	Glycine betaine
SMUL_0012	ENOG4108HQS	Glycine betaine
SMUL_0013	ENOG4105GIJ	Glycine betaine
SMUL_0014	ENOG4105C2C	drug resistance transporter, Bcr CflA
SMUL_0015	ENOG4106DSS	Tartrate dehydratase subunit alpha
SMUL_0016	ENOG4107GFK	fumarate
SMUL_0018	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
SMUL_0019	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
SMUL_0044	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_0051	ENOG4108KXV	response regulator
SMUL_0054	ENOG4108MR7	Arylsulfotransferase
SMUL_0059	ENOG4105C5I	Dehydrogenase
SMUL_0060	ENOG4108W2Y	isochorismatase
SMUL_0063	ENOG4108W3Q	Transcriptional regulator
SMUL_0065	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
SMUL_0066	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
SMUL_0069	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
SMUL_0074	ENOG4105EZV	Transcriptional regulator
SMUL_0076	ENOG4105IPS	esterase
SMUL_0077	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
SMUL_0079	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
SMUL_0080	ENOG4105BZU	Histidine kinase
SMUL_0089	ENOG4105C01	Dihydroxy-acid dehydratase
SMUL_0090	ENOG41081FY	multiple antibiotic resistance (MarC)-related
SMUL_0093	ENOG4105E0A	ABC, transporter
SMUL_0094	ENOG4105EHG	Permease protein
SMUL_0097	ENOG4107SDU	Methyl-accepting chemotaxis
SMUL_0098	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
SMUL_0100	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
SMUL_0101	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
SMUL_0102	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
SMUL_0103	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
SMUL_0107	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
SMUL_0109	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
SMUL_0110	ENOG4107QTF	adenylosuccinate lyase
SMUL_0111	ENOG4105C34	Pseudouridine synthase
SMUL_0112	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
SMUL_0113	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
SMUL_0115	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
SMUL_0116	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
SMUL_0117	ENOG4105CN5	Metallo-Beta-Lactamase
SMUL_0118	ENOG4105C2X	Arabinose 5-phosphate isomerase
SMUL_0119	ENOG4105FE9	pseudouridine synthase
SMUL_0120	ENOG4105D1H	recombination factor protein RarA
SMUL_0122	ENOG4105VM1	flagellar
SMUL_0124	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
SMUL_0125	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
SMUL_0126	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
SMUL_0128	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
SMUL_0133	ENOG410813J	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
SMUL_0135	ENOG4105C22	threonyL-tRNA synthetase
SMUL_0136	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
SMUL_0138	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
SMUL_0139	ENOG4105C58	cytochrome c oxidase accessory protein ccog
SMUL_0144	ENOG4106032	Glutathionylspermidine synthase
SMUL_0145	ENOG4108VPT	UPF0234 protein
SMUL_0147	ENOG41080IJ	Diacylglycerol kinase
SMUL_0153	ENOG4105BZU	Histidine kinase
SMUL_0154	ENOG4108STX	response regulator
SMUL_0157	ENOG4107PE3	Mammalian cell entry related domain protein
SMUL_0158	ENOG4105DHJ	ABC, transporter
SMUL_0159	ENOG4105CY3	ABC transporter, permease
SMUL_0161	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
SMUL_0162	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_0164	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SMUL_0165	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SMUL_0170	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SMUL_0172	ENOG4108YZA	Nitrogen regulatory protein pii
SMUL_0176	ENOG4105CPC	Aldo Keto reductase
SMUL_0178	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SMUL_0181	ENOG4105E5Q	amino acid AbC transporter
SMUL_0182	ENOG4106PMH	Extracellular solute-binding protein family 3
SMUL_0187	ENOG4105DIK	(ABC) transporter
SMUL_0191	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
SMUL_0193	ENOG4105CEY	Amp-dependent synthetase and ligase
SMUL_0194	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
SMUL_0195	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SMUL_0196	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SMUL_0197	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SMUL_0198	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SMUL_0202	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
SMUL_0203	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SMUL_0205	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SMUL_0206	ENOG4105D65	subunit l
SMUL_0207	ENOG4105C8S	subunit m
SMUL_0208	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SMUL_0213	ENOG4105C26	Dehydrogenase
SMUL_0214	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
SMUL_0218	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_0220	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
SMUL_0221	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
SMUL_0223	ENOG4107YV6	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
SMUL_0224	ENOG41082DI	50s ribosomal protein l31
SMUL_0229	ENOG4105CHM	Aminotransferase
SMUL_0230	ENOG4105D6E	homoserine dehydrogenase
SMUL_0231	ENOG41082UM	UPF0102 protein
SMUL_0233	ENOG4105C3M	thioredoxin reductase
SMUL_0234	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
SMUL_0236	ENOG4105N5T	Radical SAM Protein
SMUL_0239	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
SMUL_0241	ENOG4105CM2	brancheD-chain amino acid aminotransferase
SMUL_0242	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SMUL_0244	ENOG4105WPN	DNA integration recombination invertion protein
SMUL_0245	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
SMUL_0246	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
SMUL_0247	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
SMUL_0248	ENOG4105DFF	Rod shape-determining protein mreb
SMUL_0250	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
SMUL_0255	ENOG4105CUZ	uba thif-type nad fad binding protein
SMUL_0256	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
SMUL_0257	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
SMUL_0267	ENOG4105DQ6	Transposase
SMUL_0273	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SMUL_0274	ENOG4107QY8	reductase
SMUL_0277	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
SMUL_0278	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
SMUL_0280	ENOG4107R88	Chemotaxis protein (CheV)
SMUL_0281	ENOG4105CBS	Chea signal transduction histidine kinase
SMUL_0282	ENOG4108V3W	Chemotaxis protein, CheW
SMUL_0284	ENOG4105EAC	phosphoserine phosphatase
SMUL_0285	ENOG4107V25	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
SMUL_0289	ENOG4105CZX	twitching motility protein
SMUL_0291	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
SMUL_0293	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
SMUL_0294	ENOG4105CQC	Prephenate dehydratase
SMUL_0295	ENOG4105CIH	Imidazole acetol-phosphate transaminase
SMUL_0296	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
SMUL_0297	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
SMUL_0299	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
SMUL_0301	ENOG4105D3R	alkyl hydroperoxide reductase
SMUL_0302	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
SMUL_0304	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
SMUL_0307	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
SMUL_0308	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
SMUL_0310	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SMUL_0311	ENOG4105C9X	ppx gppa phosphatase
SMUL_0312	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
SMUL_0314	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SMUL_0316	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
SMUL_0318	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
SMUL_0319	ENOG4105D00	flagellar biosynthetic protein flhB
SMUL_0321	ENOG4108K5P	(LipO)protein
SMUL_0322	ENOG4105VQJ	septum formation inhibitor
SMUL_0325	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
SMUL_0327	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
SMUL_0329	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
SMUL_0330	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
SMUL_0333	ENOG4105VEQ	Cold shock protein
SMUL_0334	ENOG4105BZU	Histidine kinase
SMUL_0337	ENOG4105NQN	cytochrome C
SMUL_0339	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
SMUL_0342	ENOG4107QY8	reductase
SMUL_0343	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SMUL_0344	ENOG4105DVI	reductase, NrfD
SMUL_0345	ENOG4105BZU	Histidine kinase
SMUL_0346	ENOG4108J2R	molybdopterin oxidoreductase
SMUL_0347	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SMUL_0348	ENOG4105DVI	reductase, NrfD
SMUL_0349	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SMUL_0350	ENOG4105BZU	Histidine kinase
SMUL_0352	ENOG4105CSA	Coproporphyrinogen iii oxidase
SMUL_0354	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
SMUL_0358	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
SMUL_0360	ENOG4105BZU	Histidine kinase
SMUL_0361	ENOG4105BZU	Histidine kinase
SMUL_0362	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
SMUL_0363	ENOG4105CHR	reductase
SMUL_0364	ENOG4105CF7	AraC family transcriptional regulator
SMUL_0365	ENOG4107RDF	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
SMUL_0366	ENOG4105DUM	transcriptional regulator, lysR family
SMUL_0367	ENOG4105HMI	Membrane
SMUL_0368	ENOG4108V06	Glutathione peroxidase
SMUL_0372	ENOG4108JYZ	YitT family
SMUL_0374	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
SMUL_0375	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
SMUL_0376	ENOG4105DC7	peptidase M24
SMUL_0377	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SMUL_0378	ENOG4105FZW	flagellar biosynthesis regulator FlhF
SMUL_0379	ENOG4107R21	site-determining protein
SMUL_0381	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SMUL_0382	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
SMUL_0383	ENOG4105DD5	Flagellar motor switch protein
SMUL_0384	ENOG4108URH	decarboxylase
SMUL_0386	ENOG4105CKK	Glycosyl transferase, family 2
SMUL_0388	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
SMUL_0389	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
SMUL_0392	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
SMUL_0393	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
SMUL_0394	ENOG4105MJ2	Competence protein
SMUL_0400	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SMUL_0401	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
SMUL_0404	ENOG41082XB	radical SAM domain protein
SMUL_0408	ENOG4105DFP	Integrase
SMUL_0421	ENOG4105NI8	Cytosine-specific methyltransferase
SMUL_0431	ENOG4107WZZ	SMC domain protein
SMUL_0438	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
SMUL_0440	ENOG4107QRI	Phosphoketolase
SMUL_0441	ENOG4106V2I	dimethylaminohydrolase
SMUL_0442	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
SMUL_0443	ENOG4107R7Y	intracellular protease Pfpi family
SMUL_0449	ENOG4105BZU	Histidine kinase
SMUL_0452	ENOG4105K63	Thioredoxin
SMUL_0454	ENOG4105CFM	UPF0317 protein
SMUL_0459	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
SMUL_0460	ENOG4105EMU	Dehydrogenase
SMUL_0463	ENOG4105CP9	extracellular ligand-binding receptor
SMUL_0464	ENOG4105C32	Amino acid ABC transporter (Permease)
SMUL_0465	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
SMUL_0466	ENOG4105C0Z	ABC transporter
SMUL_0467	ENOG4108IV0	ABC, transporter
SMUL_0468	ENOG4105C26	Dehydrogenase
SMUL_0471	ENOG410802Z	Protein of unknown function (DUF328)
SMUL_0480	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
SMUL_0481	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
SMUL_0484	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
SMUL_0487	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
SMUL_0488	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
SMUL_0490	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
SMUL_0491	ENOG4108UMI	ABC transporter, permease
SMUL_0492	ENOG4105D01	(LipO)protein
SMUL_0495	ENOG4105EW9	transcriptional regulator AsnC family
SMUL_0496	ENOG4105FDR	Membrane
SMUL_0500	ENOG4108J2R	molybdopterin oxidoreductase
SMUL_0502	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SMUL_0505	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_0506	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
SMUL_0508	ENOG4108IEH	NADH dehydrogenase subunit g
SMUL_0509	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
SMUL_0511	ENOG4107UFS	subunit j
SMUL_0512	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SMUL_0513	ENOG4105D65	subunit l
SMUL_0515	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SMUL_0519	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SMUL_0520	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SMUL_0521	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SMUL_0524	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
SMUL_0528	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
SMUL_0530	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
SMUL_0532	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
SMUL_0533	ENOG4105D52	delta-aminolevulinic acid dehydratase
SMUL_0534	ENOG4105DBV	ornithine carbamoyltransferase
SMUL_0535	ENOG4105T1H	UPF0763 protein
SMUL_0536	ENOG4105D4P	Coproporphyrinogen iii oxidase
SMUL_0537	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
SMUL_0542	ENOG4105K4U	addiction module toxin, RelE StbE family
SMUL_0543	ENOG4105BZU	Histidine kinase
SMUL_0544	ENOG4107SHS	Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites (By similarity)
SMUL_0545	ENOG4105K5B	UPF0225 protein
SMUL_0548	ENOG4105BZU	Histidine kinase
SMUL_0549	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
SMUL_0550	ENOG4108S24	Fumarate reduCtase
SMUL_0551	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
SMUL_0552	ENOG4105E33	succinate dehydrogenase
SMUL_0554	ENOG410890F	Dynamin family
SMUL_0555	ENOG4105F4G	Membrane
SMUL_0556	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
SMUL_0557	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
SMUL_0559	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
SMUL_0562	ENOG4105CE9	30S ribosomal protein S2
SMUL_0565	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
SMUL_0567	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
SMUL_0569	ENOG4105C75	arginyL-tRNA synthetase
SMUL_0571	ENOG4105BZU	Histidine kinase
SMUL_0574	ENOG4105I3K	Ferric uptake regulator, Fur family
SMUL_0575	ENOG4105CA0	peroxidase
SMUL_0579	ENOG4105CP7	Triose-phosphate isomerase
SMUL_0580	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
SMUL_0583	ENOG4105CHV	Transcription elongation factor NusA
SMUL_0585	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
SMUL_0590	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
SMUL_0591	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
SMUL_0592	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
SMUL_0593	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
SMUL_0598	ENOG4107QMP	dna polymerase iii subunits gamma and tau
SMUL_0599	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
SMUL_0600	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
SMUL_0601	ENOG4105BZU	Histidine kinase
SMUL_0602	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
SMUL_0608	ENOG4105CSR	polyphosphate kinase 2
SMUL_0612	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SMUL_0613	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SMUL_0615	ENOG4108YXA	Membrane
SMUL_0616	ENOG4105C1J	atp-dependent rna helicase
SMUL_0617	ENOG4105C6Z	Gluconate
SMUL_0618	ENOG4105DDY	UPF0142 protein ycaO
SMUL_0620	ENOG4105BZU	Histidine kinase
SMUL_0621	ENOG410812K	response regulator receiver protein
SMUL_0622	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
SMUL_0623	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
SMUL_0624	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
SMUL_0626	ENOG4105VXP	Protein of unknown function DUF86
SMUL_0640	ENOG4105C32	Amino acid ABC transporter (Permease)
SMUL_0641	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
SMUL_0642	ENOG4105C0Z	ABC transporter
SMUL_0643	ENOG4108IV0	ABC, transporter
SMUL_0644	ENOG4105CRE	cytochrome C
SMUL_0652	ENOG4105CEV	competence damage-inducible protein
SMUL_0653	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
SMUL_0655	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
SMUL_0656	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
SMUL_0657	ENOG4105DWV	Homoserine O-trans-acetylase
SMUL_0660	ENOG4105D06	uba thif-type nad fad binding protein
SMUL_0661	ENOG4105CHM	Aminotransferase
SMUL_0662	ENOG4105DFU	Cell wall formation (By similarity)
SMUL_0664	ENOG4105C98	muts2 protein
SMUL_0665	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
SMUL_0666	ENOG4105KME	endoribonuclease L-psp
SMUL_0667	ENOG4107RSR	Malate quinone oxidoreductase
SMUL_0670	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
SMUL_0671	ENOG4105CN1	protease
SMUL_0673	ENOG4105CA9	Pyruvate kinase
SMUL_0675	ENOG4105K46	50S ribosomal protein l27
SMUL_0676	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SMUL_0677	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
SMUL_0678	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
SMUL_0680	ENOG4107QJE	Chromosome Partitioning Protein
SMUL_0681	ENOG4105FA0	parb-like partition protein
SMUL_0683	ENOG4105YF2	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
SMUL_0684	ENOG4105PQH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
SMUL_0685	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
SMUL_0686	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
SMUL_0687	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
SMUL_0688	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
SMUL_0689	ENOG4105E02	MotA TolQ exbB proton channel
SMUL_0690	ENOG4105M8F	Biopolymer transport protein exbD tolR
SMUL_0692	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
SMUL_0693	ENOG4105UYK	outer membrane protein a
SMUL_0695	ENOG4108YZY	peptidylprolyl cis-trans isomerase
SMUL_0697	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
SMUL_0698	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
SMUL_0699	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
SMUL_0701	ENOG4105CBC	glutamate synthase
SMUL_0702	ENOG4105BZ8	glutamate synthase
SMUL_0704	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
SMUL_0705	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
SMUL_0706	ENOG4105SCY	DNAK suppressor
SMUL_0708	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
SMUL_0712	ENOG4105DD5	Flagellar motor switch protein
SMUL_0715	ENOG4108Z0R	Transferase
SMUL_0717	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
SMUL_0724	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
SMUL_0727	ENOG4105C85	amino acid
SMUL_0728	ENOG4105HF0	Membrane
SMUL_0729	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
SMUL_0730	ENOG4105CK2	sodium dicarboxylate symporter
SMUL_0731	ENOG4105CK2	sodium dicarboxylate symporter
SMUL_0733	ENOG4105C2M	dna polymerase I
SMUL_0734	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
SMUL_0736	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
SMUL_0741	ENOG4105C4M	(Ubiquinol oxidase) subunit I
SMUL_0742	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
SMUL_0743	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
SMUL_0744	ENOG410804D	Sensor Signal Transduction Histidine Kinase
SMUL_0745	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
SMUL_0746	ENOG4105BZU	Histidine kinase
SMUL_0747	ENOG4108N3W	hemolysin secretion protein
SMUL_0748	ENOG4105CEY	Amp-dependent synthetase and ligase
SMUL_0749	ENOG4105E2X	shikimate dehydrogenase
SMUL_0750	ENOG4105CRQ	synthase (Component I)
SMUL_0754	ENOG4105CRK	lysyL-tRNA synthetase
SMUL_0757	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
SMUL_0758	ENOG4105CZX	twitching motility protein
SMUL_0759	ENOG410855J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
SMUL_0761	ENOG4108TX7	
SMUL_0764	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
SMUL_0765	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SMUL_0766	ENOG4105BZU	Histidine kinase
SMUL_0769	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
SMUL_0772	ENOG4108IYU	L-aspartate oxidase
SMUL_0774	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
SMUL_0776	ENOG4105C12	Phosphoribosylglycinamide synthetase
SMUL_0779	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
SMUL_0783	ENOG4105BZU	Histidine kinase
SMUL_0786	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
SMUL_0789	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
SMUL_0790	ENOG4105D9Q	decarboxylase (Beta subunit)
SMUL_0791	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
SMUL_0792	ENOG4105CH7	arginosuccinase
SMUL_0794	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
SMUL_0795	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
SMUL_0796	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
SMUL_0797	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
SMUL_0798	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
SMUL_0800	ENOG4108JQ1	Dehydrogenase
SMUL_0802	ENOG4107KET	secretion protein, HlyD family
SMUL_0804	ENOG4105BZS	acriflavin resistance protein
SMUL_0808	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_0810	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_0811	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
SMUL_0815	ENOG4105CBX	hi0933 family
SMUL_0818	ENOG4105BZU	Histidine kinase
SMUL_0819	ENOG4108YXA	Membrane
SMUL_0820	ENOG4106492	Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO (By similarity)
SMUL_0824	ENOG4105BZU	Histidine kinase
SMUL_0825	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
SMUL_0826	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
SMUL_0829	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
SMUL_0830	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
SMUL_0831	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
SMUL_0831	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
SMUL_0833	ENOG4105C0B	DNA polymerase III (alpha subunit)
SMUL_0834	ENOG41080XP	Cbs domain
SMUL_0837	ENOG4105BZU	Histidine kinase
SMUL_0839	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
SMUL_0840	ENOG4105C1A	potassium transporter peripheral membrane
SMUL_0843	ENOG4105CNI	cell division protein FtsW
SMUL_0844	ENOG4105C34	Pseudouridine synthase
SMUL_0846	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
SMUL_0851	ENOG410692R	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
SMUL_0852	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
SMUL_0853	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
SMUL_0854	ENOG4105EA8	2-Nitropropane dioxygenase
SMUL_0855	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
SMUL_0857	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
SMUL_0858	ENOG4105C9M	aspartyl-trna synthetase
SMUL_0859	ENOG4105BZU	Histidine kinase
SMUL_0861	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
SMUL_0862	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
SMUL_0863	ENOG4105DAA	L-lactate
SMUL_0864	ENOG4105BZU	Histidine kinase
SMUL_0865	ENOG4105F8V	Hydrolase, tatD family
SMUL_0866	ENOG41068JE	domain protein
SMUL_0867	ENOG4105K6T	rare lipoprotein A
SMUL_0868	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
SMUL_0869	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
SMUL_0872	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
SMUL_0875	ENOG4105CJN	penicillin-binding protein
SMUL_0877	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
SMUL_0879	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
SMUL_0881	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
SMUL_0886	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
SMUL_0887	ENOG4105CX6	glutaminyL-tRNA synthetase
SMUL_0889	ENOG4108W6G	cytochrome C
SMUL_0890	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
SMUL_0891	ENOG4105CRE	cytochrome C
SMUL_0895	ENOG4105MJ9	esterase
SMUL_0898	ENOG41067MG	lrgb family
SMUL_0901	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
SMUL_0903	ENOG4108N5C	SNARE associated Golgi protein-related protein
SMUL_0906	ENOG41089UC	methyltransferase, type 11
SMUL_0907	ENOG4105EMK	carboxylate amino acid amine transporter
SMUL_0913	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
SMUL_0916	ENOG4105ENE	Histidine kinase
SMUL_0919	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
SMUL_0923	ENOG4105BZ9	Cytochrome C oxidase, subunit I
SMUL_0931	ENOG4105DFS	Conserved Protein
SMUL_0934	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
SMUL_0935	ENOG4108BGM	Quinol dehydrogenase periplasmic component
SMUL_0936	ENOG4105GXZ	Ferredoxin-type protein NapH
SMUL_0937	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
SMUL_0938	ENOG4108ZNS	ferredoxin-type protein NapF
SMUL_0941	ENOG4105C3G	gtp-binding protein
SMUL_0950	ENOG4108J2R	molybdopterin oxidoreductase
SMUL_0953	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SMUL_0955	ENOG4105BZU	Histidine kinase
SMUL_0956	ENOG4105VBD	cytochrome C, class I
SMUL_0957	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SMUL_0958	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SMUL_0960	ENOG4107SDU	Methyl-accepting chemotaxis
SMUL_0962	ENOG4105BZU	Histidine kinase
SMUL_0963	ENOG4105DJ4	phosphatidylserine decarboxylase
SMUL_0964	ENOG4105C1J	atp-dependent rna helicase
SMUL_0967	ENOG4105WWK	YheO domain protein
SMUL_0968	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
SMUL_0971	ENOG4105QAX	Iron-sulfur
SMUL_0973	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
SMUL_0975	ENOG4108NIW	Leucine export protein LeuE
SMUL_0976	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SMUL_0979	ENOG4105CDY	transcriptional regulatory protein
SMUL_0984	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
SMUL_0986	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
SMUL_0987	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
SMUL_0995	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
SMUL_1013	ENOG4105DWK	Membrane
SMUL_1014	ENOG4107XM3	UPF0442 protein
SMUL_1015	ENOG4105W3S	hemerythrin-like, metal-binding protein
SMUL_1016	ENOG4105C59	p-type ATPase
SMUL_1020	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
SMUL_1021	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
SMUL_1023	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
SMUL_1025	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_1026	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_1027	ENOG4107S5G	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
SMUL_1030	ENOG4108UT2	hemolysin iii
SMUL_1032	ENOG410829K	Lysine exporter protein (Lyse ygga)
SMUL_1033	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
SMUL_1034	ENOG4107QR9	Iron-sulfur cluster binding protein
SMUL_1035	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
SMUL_1036	ENOG410631K	Membrane
SMUL_1040	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
SMUL_1045	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
SMUL_1047	ENOG4105D0M	Protease HtpX homolog
SMUL_1051	ENOG4105BZU	Histidine kinase
SMUL_1052	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
SMUL_1053	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
SMUL_1054	ENOG4108VD1	dedA family
SMUL_1055	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
SMUL_1056	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
SMUL_1058	ENOG4108YZG	isomerase
SMUL_1059	ENOG4108Z4T	Peptidase M50
SMUL_1060	ENOG4105C3F	Signal peptidase i
SMUL_1061	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
SMUL_1083	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
SMUL_1086	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
SMUL_1088	ENOG4105CB5	ATP-dependent DNA helicase recG
SMUL_1094	ENOG410821Z	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
SMUL_1095	ENOG410901F	(LipO)protein
SMUL_1096	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
SMUL_1097	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
SMUL_1098	ENOG4108UUM	single-stranded DNA-binding protein
SMUL_1100	ENOG4108VMB	DNA polymerase III subunit delta'
SMUL_1101	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
SMUL_1104	ENOG4107QMS	site-determining protein
SMUL_1105	ENOG41084TB	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
SMUL_1107	ENOG4105C79	DNA protecting protein DprA
SMUL_1108	ENOG4107TSN	permease
SMUL_1109	ENOG4108UIN	ybak prolyl-trna synthetase associated region
SMUL_1112	ENOG4105EJQ	L-serine dehydratase
SMUL_1113	ENOG4105GSH	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
SMUL_1114	ENOG4105EN6	Membrane
SMUL_1115	ENOG4105C8Y	Acetylornithine aminotransferase
SMUL_1117	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
SMUL_1118	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
SMUL_1119	ENOG4105X6C	Flagellar basal body-associated protein FliL
SMUL_1120	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
SMUL_1121	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
SMUL_1124	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
SMUL_1125	ENOG4105BZ1	(ABC) transporter
SMUL_1127	ENOG4108VD1	dedA family
SMUL_1129	ENOG4105C09	Bile acid
SMUL_1130	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
SMUL_1133	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
SMUL_1134	ENOG4105CBS	Chea signal transduction histidine kinase
SMUL_1135	ENOG4105BZU	Histidine kinase
SMUL_1136	ENOG4105BZU	Histidine kinase
SMUL_1139	ENOG4108Z66	YbaK ebsC protein
SMUL_1147	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
SMUL_1176	ENOG4105GVR	general secretion pathway protein D
SMUL_1183	ENOG4105GR3	Histidine kinase
SMUL_1184	ENOG4107RN3	metallophosphoesterase
SMUL_1185	ENOG4108YYC	ycei family
SMUL_1188	ENOG4107XPZ	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
SMUL_1191	ENOG4105XMH	SpoVT AbrB domain protein
SMUL_1192	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
SMUL_1202	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
SMUL_1203	ENOG4107YD3	Thioesterase
SMUL_1205	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
SMUL_1208	ENOG4107S73	homocitrate synthase
SMUL_1210	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SMUL_1212	ENOG4105BZU	Histidine kinase
SMUL_1214	ENOG4108STX	response regulator
SMUL_1215	ENOG4105CNW	domain protein
SMUL_1218	ENOG4105D0B	Nitrogenase protein alpha chain
SMUL_1219	ENOG4105DK8	Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN
SMUL_1220	ENOG4108J5H	Homocysteine s-methyltransferase
SMUL_1221	ENOG4105C26	Dehydrogenase
SMUL_1222	ENOG4105EGS	Mechanosensitive ion channel
SMUL_1223	ENOG4105BZU	Histidine kinase
SMUL_1224	ENOG4105BZU	Histidine kinase
SMUL_1225	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SMUL_1227	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SMUL_1230	ENOG4108VQE	nitrogen fixation protein
SMUL_1232	ENOG4106C8Q	May protect the nitrogenase Fe-Mo protein from oxidative damage (By similarity)
SMUL_1233	ENOG4105XV5	nifz family
SMUL_1235	ENOG4105KXW	Ferredoxin
SMUL_1236	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SMUL_1238	ENOG4108Z7F	N-acetyltransferase
SMUL_1243	ENOG4105K4U	addiction module toxin, RelE StbE family
SMUL_1244	ENOG4105F5P	DNA-damage-inducible protein d
SMUL_1250	ENOG4105BZU	Histidine kinase
SMUL_1255	ENOG4108VKG	metal-dependent hydrolase
SMUL_1258	ENOG4105JAB	phenazine biosynthesis protein, phzf family
SMUL_1267	ENOG4105BZU	Histidine kinase
SMUL_1268	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
SMUL_1275	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_1276	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_1277	ENOG4107QY8	reductase
SMUL_1279	ENOG4105BZU	Histidine kinase
SMUL_1280	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
SMUL_1284	ENOG4105RRV	Inherit from COG: copper resistance
SMUL_1285	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
SMUL_1287	ENOG4105D0B	Nitrogenase protein alpha chain
SMUL_1288	ENOG4105CY9	nitrogenase molybdenum-iron protein beta chain
SMUL_1291	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SMUL_1293	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
SMUL_1301	ENOG4105BZU	Histidine kinase
SMUL_1304	ENOG4105BZ8	glutamate synthase
SMUL_1305	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
SMUL_1306	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
SMUL_1307	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
SMUL_1308	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SMUL_1310	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SMUL_1313	ENOG4107SFI	Major Facilitator superfamily
SMUL_1317	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
SMUL_1318	ENOG4107QR9	Iron-sulfur cluster binding protein
SMUL_1319	ENOG4107QZB	decarboxylase
SMUL_1321	ENOG4105CJ1	ABC, transporter
SMUL_1322	ENOG4107QWP	ABC-2 type transporter
SMUL_1323	ENOG4105XMH	SpoVT AbrB domain protein
SMUL_1324	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
SMUL_1329	ENOG4105CPC	Aldo Keto reductase
SMUL_1330	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
SMUL_1331	ENOG41084IN	nitrogen fixation protein
SMUL_1337	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
SMUL_1338	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
SMUL_1341	ENOG4105BZU	Histidine kinase
SMUL_1343	ENOG4105BZU	Histidine kinase
SMUL_1344	ENOG4105DWF	phosphomethylpyrimidine kinase
SMUL_1346	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
SMUL_1348	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
SMUL_1350	ENOG4105DHT	Metal Dependent Phosphohydrolase
SMUL_1352	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_1353	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
SMUL_1355	ENOG4105C5H	ABC transporter
SMUL_1356	ENOG4108SEK	ompa motb domain protein
SMUL_1358	ENOG4108IG5	Transcriptional regulator
SMUL_1361	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
SMUL_1364	ENOG4108RCM	Nitroreductase
SMUL_1365	ENOG4108RCM	Nitroreductase
SMUL_1368	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
SMUL_1370	ENOG4108JQC	penicillin-binding protein 1A
SMUL_1375	ENOG4105DZS	Phenylacetate-CoA ligase
SMUL_1379	ENOG4108IA2	Sodium pantothenate symporter
SMUL_1382	ENOG4107TPX	flagellar hook-associated
SMUL_1385	ENOG4106H78	methyltransferase
SMUL_1386	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
SMUL_1387	ENOG4105YKR	
SMUL_1391	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
SMUL_1393	ENOG4105CHH	sulfate transporter
SMUL_1394	ENOG4105VSH	4-oxalocrotonate tautomerase
SMUL_1399	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
SMUL_1401	ENOG4105CD3	dihydroorotase
SMUL_1402	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
SMUL_1404	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
SMUL_1407	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
SMUL_1408	ENOG4105CN7	Flagellar biosynthetic protein FliP
SMUL_1409	ENOG4105DSB	aldose 1-epimerase
SMUL_1410	ENOG4105KVH	Transcriptional regulator
SMUL_1411	ENOG4105NF4	modulator of drug activity
SMUL_1413	ENOG4108M3P	Membrane
SMUL_1416	ENOG4107PU6	Membrane
SMUL_1417	ENOG4105CCT	upf0313 protein
SMUL_1418	ENOG4107QP8	phosphohexose isomerase
SMUL_1422	ENOG4105DPX	Hydrogenase, large subunit
SMUL_1423	ENOG4105E3S	small subunit
SMUL_1424	ENOG4105DPX	Hydrogenase, large subunit
SMUL_1425	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
SMUL_1426	ENOG4108USZ	hydrogenase
SMUL_1427	ENOG4108P97	
SMUL_1429	ENOG4105MRR	Transcriptional regulator (By similarity)
SMUL_1430	ENOG4105E0K	tonB-dependent siderophore receptor
SMUL_1434	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
SMUL_1435	ENOG4105CQS	hydrogenase expression formation protein HypD
SMUL_1436	ENOG4105C45	hydrogenase expression formation protein (HypE)
SMUL_1438	ENOG4107TCE	N-acetyltransferase
SMUL_1439	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
SMUL_1442	ENOG4105E9K	Isocitrate dehydrogenase
SMUL_1443	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
SMUL_1444	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
SMUL_1445	ENOG4105BZU	Histidine kinase
SMUL_1447	ENOG4107QPK	)-transporter
SMUL_1448	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
SMUL_1449	ENOG4105CQB	FAD linked oxidase domain protein
SMUL_1450	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
SMUL_1451	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
SMUL_1453	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
SMUL_1454	ENOG4107QK6	Thiamine pyrophosphate
SMUL_1459	ENOG4105C9Q	fumarate hydratase class II
SMUL_1462	ENOG41081FY	multiple antibiotic resistance (MarC)-related
SMUL_1466	ENOG4105DFA	alanine racemase domain protein
SMUL_1467	ENOG4105DZP	Membrane-associated zinc metalloprotease
SMUL_1468	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
SMUL_1469	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
SMUL_1470	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
SMUL_1472	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
SMUL_1473	ENOG4105BZ1	(ABC) transporter
SMUL_1474	ENOG4105C8N	cysteinyl-tRNA synthetase
SMUL_1475	ENOG4105CJR	Integral membrane protein (MviN
SMUL_1477	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
SMUL_1478	ENOG4105CPF	Cell wall formation (By similarity)
SMUL_1482	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
SMUL_1483	ENOG4105C6K	Malic enzyme
SMUL_1484	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
SMUL_1489	ENOG4107QHF	type ii secretion system protein e
SMUL_1492	ENOG4105GVR	general secretion pathway protein D
SMUL_1496	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
SMUL_1497	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
SMUL_1498	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
SMUL_1501	ENOG4105CDH	Citrulline--aspartate ligase
SMUL_1502	ENOG410854I	s4 domain protein
SMUL_1503	ENOG4107QYG	anthranilate phosphoribosyltransferase
SMUL_1504	ENOG4105K8N	protein family UPF0079, ATPase
SMUL_1505	ENOG4108IUZ	ABC transporter
SMUL_1506	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SMUL_1511	ENOG4107WZZ	SMC domain protein
SMUL_1512	ENOG4105ESI	atpase involved in dna repair
SMUL_1519	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_1520	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SMUL_1526	ENOG4107EFR	Flavocytochrome c
SMUL_1534	ENOG4105BZU	Histidine kinase
SMUL_1535	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SMUL_1538	ENOG4105CQZ	Histidine kinase
SMUL_1539	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
SMUL_1541	ENOG4108BGM	Quinol dehydrogenase periplasmic component
SMUL_1543	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
SMUL_1545	ENOG4108YZT	Adenosylcobinamide kinase
SMUL_1547	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
SMUL_1549	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
SMUL_1551	ENOG4107PPM	cobalt chelatase
SMUL_1552	ENOG4105EHG	Permease protein
SMUL_1553	ENOG4105E0A	ABC, transporter
SMUL_1555	ENOG41081F0	Precorrin-8x methylmutase
SMUL_1556	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
SMUL_1558	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
SMUL_1559	ENOG4105DVK	Precorrin-2 c20-methyltransferase
SMUL_1560	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
SMUL_1561	ENOG4108P62	biosynthesis protein (CbiG)
SMUL_1562	ENOG4105E4R	Precorrin-3B C17-methyltransferase
SMUL_1564	ENOG4108JTQ	reductase
SMUL_1565	ENOG4105BZ1	(ABC) transporter
SMUL_1566	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
SMUL_1568	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
SMUL_1569	ENOG4108IG5	Transcriptional regulator
SMUL_1597	ENOG410841J	DNA-binding protein Hu
SMUL_1598	ENOG4105DTJ	flagellar hook-associated protein
SMUL_1599	ENOG4105CNU	cell division protein FtsK
SMUL_1600	ENOG4107QIJ	Aconitate hydratase 2
SMUL_1601	ENOG4108YZY	peptidylprolyl cis-trans isomerase
SMUL_1602	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
SMUL_1603	ENOG4105C6X	Major Facilitator
SMUL_1607	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
SMUL_1608	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_1609	ENOG4105K4P	CoA-binding domain protein
SMUL_1610	ENOG4105C7B	Threonine dehydratase
SMUL_1612	ENOG4105CDA	abc transporter atp-binding protein
SMUL_1613	ENOG4105DRP	amino acid AbC transporter
SMUL_1614	ENOG4105EZ7	amino acid ABC transporter
SMUL_1615	ENOG4107QXX	ABC transporter
SMUL_1616	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
SMUL_1619	ENOG4107T5V	SNARE associated Golgi
SMUL_1622	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
SMUL_1625	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
SMUL_1626	ENOG4105QTX	Pfam:UPF0153
SMUL_1628	ENOG4105DK0	Indole-3-glycerol phosphate synthase
SMUL_1630	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
SMUL_1632	ENOG4105G01	cobalamin (vitamin B12) biosynthesis CbiM protein
SMUL_1636	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
SMUL_1637	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
SMUL_1640	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
SMUL_1642	ENOG4105C9X	ppx gppa phosphatase
SMUL_1643	ENOG4105C7K	acetolactate synthase
SMUL_1644	ENOG4108ZP8	Acetolactate synthase small subunit
SMUL_1645	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
SMUL_1647	ENOG4105BZ8	glutamate synthase
SMUL_1649	ENOG4105D0B	Nitrogenase protein alpha chain
SMUL_1650	ENOG4108JUA	Transcriptional regulator
SMUL_1652	ENOG4105CY9	nitrogenase molybdenum-iron protein beta chain
SMUL_1653	ENOG4105SJ7	Fe-only nitrogenase subunit delta
SMUL_1654	ENOG4107V0H	Nitrogenase protein alpha chain
SMUL_1655	ENOG4105D7W	serine acetyltransferase
SMUL_1656	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
SMUL_1657	ENOG4105CUT	histidyl-tRNA synthetase
SMUL_1658	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
SMUL_1659	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
SMUL_1660	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
SMUL_1663	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_1664	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
SMUL_1665	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
SMUL_1674	ENOG4105VYW	UPF0251 protein
SMUL_1675	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
SMUL_1676	ENOG4105DVM	PP-loop domain protein
SMUL_1677	ENOG4105C8M	UPF0272 protein
SMUL_1678	ENOG4105QUH	Domain of unknown function (DUF2088)
SMUL_1679	ENOG4107GFK	fumarate
SMUL_1681	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
SMUL_1682	ENOG4105BZU	Histidine kinase
SMUL_1688	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SMUL_1689	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
SMUL_1691	ENOG4105D49	3-dehydroquinate synthase
SMUL_1693	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
SMUL_1698	ENOG4105DEN	Luciferase family
SMUL_1699	ENOG4105CHR	reductase
SMUL_1701	ENOG4105D29	Helix-turn-helix type 11 domain protein
SMUL_1702	ENOG4105FE9	pseudouridine synthase
SMUL_1703	ENOG4105C7K	acetolactate synthase
SMUL_1705	ENOG4105CSV	Glutaminase
SMUL_1709	ENOG4107Z3H	Transcriptional regulator, TetR family
SMUL_1715	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_1740	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
SMUL_1762	ENOG4105D5G	Transposase
SMUL_1773	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SMUL_1778	ENOG4105K70	DNA-binding protein
SMUL_1802	ENOG41061MD	high-affinity nickel-transporter
SMUL_1819	ENOG4105EKQ	RNA-directed DNA polymerase
SMUL_1832	ENOG4108UUM	single-stranded DNA-binding protein
SMUL_1897	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SMUL_1899	ENOG4108RAC	Rubrerythrin
SMUL_1901	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
SMUL_1902	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
SMUL_1905	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
SMUL_1906	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
SMUL_1907	ENOG4105EAH	synthase
SMUL_1912	ENOG4105C6T	cysteine synthase
SMUL_1913	ENOG4105BZU	Histidine kinase
SMUL_1914	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
SMUL_1915	ENOG4105CH5	extracellular solute-binding protein, family 7
SMUL_1916	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
SMUL_1918	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
SMUL_1920	ENOG4105D2N	Aldolase
SMUL_1921	ENOG4105EIN	peptidylprolyl cis-trans isomerase
SMUL_1924	ENOG4105CIN	aminoacyl-histidine dipeptidase
SMUL_1926	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
SMUL_1929	ENOG4105C4K	Nad synthetase
SMUL_1930	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
SMUL_1932	ENOG4105CAS	nag kinase
SMUL_1933	ENOG4107QID	Threonine synthase
SMUL_1934	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
SMUL_1937	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
SMUL_1938	ENOG4105CSR	polyphosphate kinase 2
SMUL_1939	ENOG4105CFG	Acts as a chaperone (By similarity)
SMUL_1940	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SMUL_1941	ENOG4108122	heat-inducible transcription repressor
SMUL_1944	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
SMUL_1946	ENOG4105D7B	Flagellar biosynthesis protein flha
SMUL_1947	ENOG4108KA0	Inherit from COG: Phosphoesterase, DHHA1
SMUL_1949	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
SMUL_1950	ENOG4106TD9	Diguanylate cyclase
SMUL_1951	ENOG4105DTN	riboflavin biosynthesis protein ribF
SMUL_1952	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
SMUL_1953	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
SMUL_1954	ENOG4105EJ9	Membrane
SMUL_1956	ENOG4105EEI	dihydropteroate synthase
SMUL_1959	ENOG4105CFH	Aspartokinase
SMUL_1960	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
SMUL_1961	ENOG4105CSA	Coproporphyrinogen iii oxidase
SMUL_1962	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
SMUL_1963	ENOG4105KNI	merR family transcriptional Regulator
SMUL_1964	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
SMUL_1965	ENOG4105C0H	protease
SMUL_1966	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SMUL_1967	ENOG4105BZU	Histidine kinase
SMUL_1970	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
SMUL_1972	ENOG4105BZU	Histidine kinase
SMUL_1973	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
SMUL_1974	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
SMUL_1976	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
SMUL_1977	ENOG4108512	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
SMUL_1980	ENOG4105DJI	Methylaspartate mutase, E subunit
SMUL_2004	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
SMUL_2007	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
SMUL_2008	ENOG4105CN1	protease
SMUL_2010	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
SMUL_2011	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
SMUL_2013	ENOG4105E9Q	Acyl-transferase
SMUL_2014	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
SMUL_2015	ENOG4107VXZ	Hydrolase
SMUL_2019	ENOG4105C7Z	Conserved Protein
SMUL_2020	ENOG41085GJ	domain protein
SMUL_2028	ENOG4107QUV	Domain protein
SMUL_2033	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
SMUL_2037	ENOG4105DHT	Metal Dependent Phosphohydrolase
SMUL_2038	ENOG4105CGY	Dna recombination protein
SMUL_2040	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
SMUL_2042	ENOG4105EIN	peptidylprolyl cis-trans isomerase
SMUL_2043	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
SMUL_2044	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
SMUL_2046	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
SMUL_2047	ENOG4105D0M	Protease HtpX homolog
SMUL_2049	ENOG4105C5H	ABC transporter
SMUL_2050	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_2052	ENOG4105VG1	fes assembly suf system protein
SMUL_2055	ENOG4105DC1	bifunctional purine biosynthesis protein purh
SMUL_2056	ENOG4105KVY	Required for disulfide bond formation in some proteins (By similarity)
SMUL_2059	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
SMUL_2060	ENOG4105C87	Aminotransferase class I and II
SMUL_2064	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
SMUL_2065	ENOG4105BZU	Histidine kinase
SMUL_2067	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
SMUL_2068	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
SMUL_2074	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
SMUL_2075	ENOG4105EAB	amino acid AbC transporter
SMUL_2076	ENOG4105E5Q	amino acid AbC transporter
SMUL_2079	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SMUL_2080	ENOG4105BZU	Histidine kinase
SMUL_2081	ENOG4105BZU	Histidine kinase
SMUL_2082	ENOG4105CY0	Metallo-Beta-Lactamase
SMUL_2083	ENOG4108IQE	Amp-dependent synthetase and ligase
SMUL_2085	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
SMUL_2086	ENOG4105C08	Histidine kinase
SMUL_2087	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
SMUL_2089	ENOG4107ZYR	domain protein
SMUL_2090	ENOG4105E0X	reductase
SMUL_2093	ENOG4105MFX	4-diphosphocytidyl-2c-methyl-d-erythritol synthase
SMUL_2094	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
SMUL_2095	ENOG4105DZS	Phenylacetate-CoA ligase
SMUL_2096	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
SMUL_2102	ENOG4105EB3	Histidine kinase
SMUL_2105	ENOG4105DS1	cytochrome b561
SMUL_2108	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SMUL_2110	ENOG4105PGM	cation diffusion facilitator family transporter
SMUL_2114	ENOG4108ESX	Receptor
SMUL_2116	ENOG4105D64	Mechanosensitive ion channel
SMUL_2123	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
SMUL_2127	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
SMUL_2132	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
SMUL_2133	ENOG4108NIW	Leucine export protein LeuE
SMUL_2134	ENOG4108594	Permease of the drug metabolite transporter
SMUL_2136	ENOG4105BZU	Histidine kinase
SMUL_2137	ENOG4108YZA	Nitrogen regulatory protein pii
SMUL_2139	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
SMUL_2142	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SMUL_2147	ENOG4105NBK	UPF0345 protein
SMUL_2148	ENOG4105BZU	Histidine kinase
SMUL_2149	ENOG4105CBX	hi0933 family
SMUL_2151	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
SMUL_2152	ENOG4105CIY	formyltetrahydrofolate deformylase
SMUL_2153	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
SMUL_2156	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
SMUL_2157	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
SMUL_2158	ENOG4105DKW	ABC transporter
SMUL_2162	ENOG4105CGK	Exodeoxyribonuclease III
SMUL_2165	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_2167	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
SMUL_2168	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
SMUL_2169	ENOG4108W6G	cytochrome C
SMUL_2170	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
SMUL_2171	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_2173	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
SMUL_2175	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_2176	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_2177	ENOG4108U5N	UPF0316 protein
SMUL_2179	ENOG4105BZU	Histidine kinase
SMUL_2182	ENOG4105C9U	ATP-dependent DNA helicase RecQ
SMUL_2185	ENOG4105C1J	atp-dependent rna helicase
SMUL_2187	ENOG4105BZU	Histidine kinase
SMUL_2188	ENOG4105DHQ	Histidine kinase
SMUL_2189	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
SMUL_2195	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
SMUL_2196	ENOG4105CR4	methylisocitrate lyase
SMUL_2197	ENOG4105BZN	citrate synthase
SMUL_2198	ENOG4105DXD	2-methylcitrate dehydratase
SMUL_2200	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
SMUL_2202	ENOG4108UMN	azlc family
SMUL_2204	ENOG4105CGA	flagellar basal-body rod protein FlgG
SMUL_2205	ENOG4105CGA	flagellar basal-body rod protein FlgG
SMUL_2206	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SMUL_2208	ENOG4105KVH	Transcriptional regulator
SMUL_2211	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
SMUL_2212	ENOG4107QN1	sodium solute
SMUL_2213	ENOG41062QD	Membrane
SMUL_2214	ENOG4108STX	response regulator
SMUL_2216	ENOG4105DWY	Agmatine deiminase
SMUL_2218	ENOG4105CE1	Ferrous iron transport protein b
SMUL_2219	ENOG4107K9B	ferrous iron transport protein
SMUL_2224	ENOG4105X1Q	TOBE domain protein
SMUL_2225	ENOG4107VIJ	nudix hydrolase
SMUL_2226	ENOG4105D7N	magnesium and cobalt transport protein CorA
SMUL_2227	ENOG4105DR5	peptidase
SMUL_2229	ENOG4105CQB	FAD linked oxidase domain protein
SMUL_2230	ENOG4107S2Z	UPF0761 membrane protein
SMUL_2232	ENOG4105CDU	Replicative dna helicase
SMUL_2232	ENOG4105CDU	Replicative dna helicase
SMUL_2233	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
SMUL_2234	ENOG4105C25	Primosomal protein n'
SMUL_2235	ENOG4105KHS	type IV fimbrial pilin protein
SMUL_2239	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
SMUL_2242	ENOG4108Z0R	Transferase
SMUL_2243	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
SMUL_2244	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
SMUL_2245	ENOG4105DJV	ribulose-phosphate 3-epimerase
SMUL_2246	ENOG4105VB9	50S ribosomal protein l28
SMUL_2247	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
SMUL_2250	ENOG4105D48	metallophosphoesterase
SMUL_2251	ENOG4108JA2	transcriptioN-repair coupling factor
SMUL_2253	ENOG4105DR5	peptidase
SMUL_2254	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
SMUL_2255	ENOG4105BZU	Histidine kinase
SMUL_2257	ENOG4105C8T	Leucyl-tRNA synthetase
SMUL_2258	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
SMUL_2259	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
SMUL_2260	ENOG4105VIE	preprotein translocase, subunit YajC
SMUL_2261	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
SMUL_2262	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
SMUL_2264	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
SMUL_2265	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
SMUL_2266	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
SMUL_2269	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
SMUL_2270	ENOG41085EF	Carbon storage regulator
SMUL_2271	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
SMUL_2272	ENOG4105C4R	Atp-dependent dna helicase
SMUL_2273	ENOG4105DUM	transcriptional regulator, lysR family
SMUL_2277	ENOG4105CRQ	synthase (Component I)
SMUL_2278	ENOG4105CXT	aspartate transcarbamylase
SMUL_2280	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
SMUL_2286	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
SMUL_2287	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
SMUL_2288	ENOG4105V3S	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
SMUL_2289	ENOG4105VB6	UPF0109 protein
SMUL_2291	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SMUL_2292	ENOG4105EI2	Pseudouridine synthase
SMUL_2293	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
SMUL_2295	ENOG4105EGD	dinuclear metal center protein, YbgI family
SMUL_2296	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
SMUL_2298	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
SMUL_2299	ENOG4105CFP	Peptidase U32
SMUL_2301	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
SMUL_2302	ENOG4105C5F	glutamine synthetase
SMUL_2303	ENOG4108JQC	penicillin-binding protein 1A
SMUL_2305	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
SMUL_2306	ENOG4107YJQ	MAF-like protein
SMUL_2308	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
SMUL_2310	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
SMUL_2311	ENOG4105BZU	Histidine kinase
SMUL_2312	ENOG4107QY8	reductase
SMUL_2313	ENOG4105QAX	Iron-sulfur
SMUL_2314	ENOG4107KGK	dmso reductase anchor subunit
SMUL_2315	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
SMUL_2319	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
SMUL_2322	ENOG4108ZC9	flagellar basal-body rod protein flgc
SMUL_2323	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
SMUL_2324	ENOG4105CNI	cell division protein FtsW
SMUL_2328	ENOG4105HKU	nucleoside recognition domain-containing protein
SMUL_2330	ENOG4108TVT	permease
SMUL_2338	ENOG4105DDQ	anthranilate synthase
SMUL_2339	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
SMUL_2340	ENOG4105CEY	Amp-dependent synthetase and ligase
SMUL_2341	ENOG41082BM	Transcriptional regulator, arsr family
SMUL_2345	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
SMUL_2346	ENOG4105CHY	citrate lyase, alpha
SMUL_2347	ENOG4105CI0	Citrate lyase
SMUL_2349	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
SMUL_2350	ENOG4108KK1	membrane protein AbrB duplication
SMUL_2352	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
SMUL_2353	ENOG4108MRH	transcriptional regulatory protein
SMUL_2357	ENOG4105BZU	Histidine kinase
SMUL_2358	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SMUL_2359	ENOG4105D94	Major Facilitator Superfamily
SMUL_2360	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
SMUL_2361	ENOG4105C7N	Xanthine uracil vitamin C permease
SMUL_2362	ENOG4105DVY	radical SAM domain protein
SMUL_2365	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
SMUL_2367	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
SMUL_2368	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
SMUL_2369	ENOG4105BZU	Histidine kinase
SMUL_2375	ENOG4105EYW	Ion transport protein
SMUL_2380	ENOG4105C5H	ABC transporter
SMUL_2382	ENOG4105BZU	Histidine kinase
SMUL_2383	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
SMUL_2384	ENOG4108JPZ	Monovalent cation H antiporter subunit D
SMUL_2385	ENOG4107TDF	Formate hydrogenlyase subunit 4
SMUL_2386	ENOG4107WQX	hydrogenase 4 membrane subunit
SMUL_2387	ENOG4108JPZ	Monovalent cation H antiporter subunit D
SMUL_2388	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SMUL_2390	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
SMUL_2395	ENOG4105C22	threonyL-tRNA synthetase
SMUL_2397	ENOG4105CUZ	uba thif-type nad fad binding protein
SMUL_2398	ENOG4105BZU	Histidine kinase
SMUL_2401	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
SMUL_2402	ENOG4105D1F	ATP-binding protein
SMUL_2403	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
SMUL_2408	ENOG4108YYC	ycei family
SMUL_2409	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
SMUL_2410	ENOG4108PQF	modD protein
SMUL_2411	ENOG4105ECW	sulfate abc transporter
SMUL_2413	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
SMUL_2414	ENOG4105E0C	molybdate abc transporter
SMUL_2416	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
SMUL_2417	ENOG4105F4R	Transcriptional regulator mode
SMUL_2418	ENOG4105DZ1	carboxypeptidase
SMUL_2419	ENOG4105II7	pyrroline-5-carboxylate reductase
SMUL_2420	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SMUL_2421	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SMUL_2422	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
SMUL_2423	ENOG4105DFG	type I secretion outer membrane protein
SMUL_2426	ENOG4105D64	Mechanosensitive ion channel
SMUL_2442	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
SMUL_2443	ENOG4105M7K	Involved in the transcription termination process (By similarity)
SMUL_2444	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
SMUL_2447	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
SMUL_2448	ENOG4105DJP	Membrane
SMUL_2449	ENOG4105D64	Mechanosensitive ion channel
SMUL_2450	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
SMUL_2452	ENOG4105C31	Tryptophanyl-tRNA synthetase
SMUL_2453	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
SMUL_2455	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
SMUL_2456	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
SMUL_2458	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
SMUL_2459	ENOG4107RQ5	Methylates ribosomal protein L11 (By similarity)
SMUL_2461	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
SMUL_2462	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
SMUL_2465	ENOG4105C5E	polysaccharide biosynthesis protein
SMUL_2466	ENOG4105ESV	Glycosyl transferase, family 4
SMUL_2468	ENOG4108RT7	Glycosyl transferase, family 2
SMUL_2469	ENOG4108TMJ	glycosyl transferase
SMUL_2470	ENOG4108UW5	maltose o-acetyltransferase
SMUL_2473	ENOG4105EVB	acetyltransferase
SMUL_2476	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
SMUL_2477	ENOG4108SMP	Nad-dependent epimerase dehydratase
SMUL_2478	ENOG4105FAW	cDP-glucose 4,6-dehydratase
SMUL_2479	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
SMUL_2480	ENOG4105C30	Nad-dependent epimerase dehydratase
SMUL_2482	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
SMUL_2486	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
SMUL_2487	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
SMUL_2488	ENOG4107QKV	phosphomannomutase
SMUL_2497	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
SMUL_2498	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
SMUL_2499	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
SMUL_2503	ENOG4105C59	p-type ATPase
SMUL_2504	ENOG4105BZU	Histidine kinase
SMUL_2505	ENOG4105T38	integral membrane protein
SMUL_2506	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SMUL_2507	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
SMUL_2509	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
SMUL_2510	ENOG4108R6K	riboflavin synthase, subunit alpha
SMUL_2511	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_2512	ENOG4107R7A	Allophanate hydrolase subunit 2
SMUL_2514	ENOG4105E7W	lamb ycsf family protein
SMUL_2515	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
SMUL_2518	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SMUL_2519	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
SMUL_2520	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
SMUL_2521	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SMUL_2522	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SMUL_2525	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
SMUL_2526	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
SMUL_2527	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
SMUL_2528	ENOG4105CHR	reductase
SMUL_2529	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
SMUL_2531	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
SMUL_2533	ENOG4105D3Q	Sugar transferase
SMUL_2535	ENOG4108RT7	Glycosyl transferase, family 2
SMUL_2537	ENOG4108RG3	short-chain dehydrogenase reductase
SMUL_2538	ENOG4105IQ5	FAD linked oxidase domain protein
SMUL_2540	ENOG4106YN8	Prenyltransferase
SMUL_2546	ENOG4105EXC	Acyl-transferase
SMUL_2548	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
SMUL_2558	ENOG4105EY8	ABC transporter
SMUL_2565	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
SMUL_2566	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
SMUL_2567	ENOG4105CMR	udp-glucose 4-epimerase
SMUL_2568	ENOG4105DB1	molybdopterin oxidoreductase
SMUL_2570	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SMUL_2571	ENOG4105BZU	Histidine kinase
SMUL_2572	ENOG4105ETX	regulatoR
SMUL_2573	ENOG4108M8H	domain protein
SMUL_2577	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
SMUL_2580	ENOG4105CJ3	phosphate transporter
SMUL_2581	ENOG4105C1J	atp-dependent rna helicase
SMUL_2582	ENOG4108UPT	UPF0178 protein
SMUL_2584	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
SMUL_2586	ENOG4105C8U	phosphate abc transporter
SMUL_2587	ENOG4105PWN	phosphate abc transporter
SMUL_2588	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_2589	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
SMUL_2590	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
SMUL_2591	ENOG4107QPK	)-transporter
SMUL_2592	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_2594	ENOG4108W2P	Methyl-accepting chemotaxis
SMUL_2597	ENOG4105EFI	regulatoR
SMUL_2598	ENOG4105BZU	Histidine kinase
SMUL_2599	ENOG4105NAU	thioesterase Superfamily protein
SMUL_2605	ENOG4105KVH	Transcriptional regulator
SMUL_2606	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
SMUL_2608	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
SMUL_2609	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
SMUL_2617	ENOG4105C57	major facilitator superfamily
SMUL_2619	ENOG4105BZS	acriflavin resistance protein
SMUL_2620	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
SMUL_2623	ENOG4108ZPB	UPF0306 protein
SMUL_2624	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
SMUL_2625	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
SMUL_2630	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
SMUL_2631	ENOG4107XGZ	Hydrolase
SMUL_2633	ENOG4105CDV	Ompa motb domain protein
SMUL_2636	ENOG4108R3E	Dna-3-methyladenine glycosylase i
SMUL_2638	ENOG4107QW4	alcohol dehydrogenase
SMUL_2640	ENOG4107R4J	Chloride channel
SMUL_2641	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
SMUL_2644	ENOG4105R48	this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase
SMUL_2646	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
SMUL_2655	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
SMUL_2656	ENOG4108PYU	two-component system response regulator
SMUL_2659	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
SMUL_2663	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
SMUL_2664	ENOG4105CYE	ATP phosphoribosyltransferase regulatory subunit
SMUL_2665	ENOG4107UUH	Aminotransferase
SMUL_2666	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_2667	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_2668	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
SMUL_2669	ENOG4105CV1	Transketolase (EC 2.2.1.1)
SMUL_2672	ENOG41084FT	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
SMUL_2673	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
SMUL_2674	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
SMUL_2677	ENOG4108ZT0	50S ribosomal protein l17
SMUL_2678	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
SMUL_2680	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
SMUL_2681	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SMUL_2682	ENOG41067V7	50S ribosomal protein L36
SMUL_2683	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
SMUL_2684	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
SMUL_2685	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
SMUL_2686	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
SMUL_2691	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
SMUL_2692	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SMUL_2694	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
SMUL_2695	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
SMUL_2696	ENOG41084HJ	50s ribosomal protein l29
SMUL_2698	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
SMUL_2699	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
SMUL_2702	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
SMUL_2703	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
SMUL_2707	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
SMUL_2708	ENOG4107SJW	iron permease, FTR1
SMUL_2713	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SMUL_2718	ENOG4105CE1	Ferrous iron transport protein b
SMUL_2719	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
SMUL_2720	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
SMUL_2721	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
SMUL_2723	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
SMUL_2724	ENOG4105CDH	Citrulline--aspartate ligase
SMUL_2727	ENOG4105BZU	Histidine kinase
SMUL_2728	ENOG4108UNF	response regulator
SMUL_2729	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
SMUL_2730	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
SMUL_2731	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
SMUL_2732	ENOG4105E0F	Histidine kinase
SMUL_2733	ENOG4105BZU	Histidine kinase
SMUL_2736	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_2737	ENOG4108V3W	Chemotaxis protein, CheW
SMUL_2738	ENOG4108VYJ	response regulator receiver protein
SMUL_2739	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
SMUL_2761	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
SMUL_2762	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
SMUL_2765	ENOG4105CE1	Ferrous iron transport protein b
SMUL_2766	ENOG4105XFK	Ferrous iron transport protein A
SMUL_2768	ENOG4105CNM	Receptor
SMUL_2773	ENOG4105M15	transport protein ExbD
SMUL_2774	ENOG4105M8K	biopolymer transport protein
SMUL_2778	ENOG4105D5T	phosphonate abc transporter
SMUL_2781	ENOG4105PAD	Hydrolase
SMUL_2782	ENOG4105D7X	high-affinity nickel-transporter
SMUL_2783	ENOG4105D7X	high-affinity nickel-transporter
SMUL_2787	ENOG4105N14	lysine exporter protein LysE YggA
SMUL_2788	ENOG4105ECP	epimerase
SMUL_2794	ENOG410829K	Lysine exporter protein (Lyse ygga)
SMUL_2797	ENOG4105FR1	rard protein
SMUL_2799	ENOG4105DHQ	Histidine kinase
SMUL_2800	ENOG4105DIJ	Phosphoethanolamine transferase
SMUL_2802	ENOG4107XTP	(EAL) domain protein
SMUL_2803	ENOG4105BZU	Histidine kinase
SMUL_2806	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_2809	ENOG4105VYW	UPF0251 protein
SMUL_2810	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
SMUL_2811	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
SMUL_2816	ENOG4108IJ0	Aspartate ammonia-lyase
SMUL_2817	ENOG4108IJ0	Aspartate ammonia-lyase
SMUL_2818	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
SMUL_2819	ENOG4105HDK	L-asparaginase
SMUL_2820	ENOG4105BZU	Histidine kinase
SMUL_2821	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
SMUL_2824	ENOG4105BZU	Histidine kinase
SMUL_2825	ENOG4107R3N	Filamentation induced by cAMP protein fic
SMUL_2827	ENOG4105DZR	Type I site-specific deoxyribonuclease
SMUL_2832	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
SMUL_2837	ENOG4105CRE	cytochrome C
SMUL_2838	ENOG4105DVI	reductase, NrfD
SMUL_2839	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SMUL_2840	ENOG4108V1T	peptidylprolyl cis-trans isomerase
SMUL_2841	ENOG4105V2T	cytochrome C
SMUL_2842	ENOG4105BZU	Histidine kinase
SMUL_2844	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_2849	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
SMUL_2850	ENOG4108VD1	dedA family
SMUL_2854	ENOG4105M15	transport protein ExbD
SMUL_2855	ENOG4105M8K	biopolymer transport protein
SMUL_2856	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
SMUL_2857	ENOG4105VFE	sira family
SMUL_2859	ENOG4106TNF	Periplasmic binding protein
SMUL_2860	ENOG4105BZU	Histidine kinase
SMUL_2864	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
SMUL_2865	ENOG4105C8W	ABC transporter
SMUL_2866	ENOG4105D38	putrescine abc transporter
SMUL_2867	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
SMUL_2868	ENOG41066FR	extracellular solute-binding protein
SMUL_2870	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
SMUL_2872	ENOG4105QAX	Iron-sulfur
SMUL_2880	ENOG4105EHG	Permease protein
SMUL_2881	ENOG4105S10	periplasmic binding protein
SMUL_2884	ENOG4105M15	transport protein ExbD
SMUL_2885	ENOG4105M8K	biopolymer transport protein
SMUL_2886	ENOG4105F4R	Transcriptional regulator mode
SMUL_2891	ENOG4108BSC	Methyltransferase
SMUL_2893	ENOG4105WMR	Protein CrcB homolog
SMUL_2898	ENOG4105ID8	Transcriptional regulator, ARAC family
SMUL_2900	ENOG4105QAX	Iron-sulfur
SMUL_2906	ENOG4105BZU	Histidine kinase
SMUL_2907	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
SMUL_2908	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
SMUL_2909	ENOG4105EM7	Selenocysteine-specific translation elongation factor
SMUL_2913	ENOG4105C2I	pirin domain protein
SMUL_2920	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SMUL_2921	ENOG4105BZU	Histidine kinase
SMUL_2928	ENOG4105C84	Histidine ammonia-lyase
SMUL_2929	ENOG4105CHR	reductase
SMUL_2933	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
SMUL_2936	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
SMUL_2937	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
SMUL_2938	ENOG4105C1J	atp-dependent rna helicase
SMUL_2944	ENOG4108KS2	transglutaminase domain protein
SMUL_2946	ENOG4105DVP	Adenine-specific
SMUL_2950	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
SMUL_2952	ENOG4105EIG	urea carboxylase-associated protein 1
SMUL_2953	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
SMUL_2954	ENOG4108UMI	ABC transporter, permease
SMUL_2956	ENOG4105BZU	Histidine kinase
SMUL_2959	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
SMUL_2962	ENOG4105C4Y	ABC transporter
SMUL_2964	ENOG4107RCV	ABC transporter, permease
SMUL_2965	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
SMUL_2966	ENOG4105C08	Histidine kinase
SMUL_2967	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
SMUL_2968	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
SMUL_2969	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
SMUL_2970	ENOG4105CKI	cobalamin synthesis protein
SMUL_2973	ENOG4105BZU	Histidine kinase
SMUL_2975	ENOG4108P2H	Inner membrane protein YjiG
SMUL_2976	ENOG41074DU	domain protein
SMUL_2979	ENOG4108NVR	Methyl-accepting chemotaxis
SMUL_2980	ENOG4105E1F	short-chain dehydrogenase reductase
SMUL_2983	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
SMUL_2984	ENOG4105CA3	membrane-bound lytic murein transglycosylase
SMUL_2986	ENOG4107RDB	Major Facilitator
SMUL_2987	ENOG4105W39	Membrane
SMUL_2991	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
SMUL_2992	ENOG4108ZEX	molybdopterin converting factor, subunit 2
SMUL_2994	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
SMUL_2995	ENOG4105C3J	Cysteine desulfurase
SMUL_2996	ENOG4108JIR	Flagellum-specific ATP synthase
SMUL_2997	ENOG4105EUJ	GTP cyclohydrolase i
SMUL_2999	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
SMUL_3002	ENOG4105C0P	Mg chelatase subunit ChlI
SMUL_3003	ENOG4108ENG	carbohydrate kinase, YjeF related protein
SMUL_3004	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
SMUL_3005	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
SMUL_3017	ENOG4105C10	Electron transfer flavoprotein
SMUL_3018	ENOG4107EFR	Flavocytochrome c
SMUL_3019	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
SMUL_3028	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
SMUL_3030	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SMUL_3031	ENOG4107QY8	reductase
SMUL_3036	ENOG4105BZU	Histidine kinase
SMUL_3037	ENOG4105C26	Dehydrogenase
SMUL_3040	ENOG4108JQ1	Dehydrogenase
SMUL_3045	ENOG4105BZU	Histidine kinase
SMUL_3049	ENOG4105C8Q	Methyl-accepting chemotaxis
SMUL_3050	ENOG4108DBC	nitroreductase
SMUL_3057	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
SMUL_3058	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SMUL_3063	ENOG4105D17	glycoside hydrolase, family 3 domain protein
SMUL_3069	ENOG4108HYG	acetyltransferase
SMUL_3070	ENOG4108YYH	Nadph-dependent fmn reductase
SMUL_3074	ENOG4108IJF	Heavy metal efflux pump, CzcA
SMUL_3075	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
SMUL_3079	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
SMUL_3081	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
SMUL_3084	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
SMUL_3086	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
SMUL_3087	ENOG4105C11	sulfate adenylyltransferase), subunit 2
SMUL_3088	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
SMUL_3090	ENOG4105D06	uba thif-type nad fad binding protein
SMUL_3092	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
SMUL_3094	ENOG4108IQK	o-acetylhomoserine
SMUL_3096	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
SMUL_3101	ENOG4105GR3	Histidine kinase
SMUL_3103	ENOG4105BZU	Histidine kinase
SMUL_3106	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
SMUL_3110	ENOG4105PGM	cation diffusion facilitator family transporter
SMUL_3115	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
SMUL_3116	ENOG4108UXE	Protein tyrosine phosphatase
SMUL_3117	ENOG4107R5R	arsenical pump membrane protein
SMUL_3118	ENOG4108UXE	Protein tyrosine phosphatase
SMUL_3120	ENOG4108K28	Arsenite oxidase, large subunit
SMUL_3123	ENOG4105WMR	Protein CrcB homolog
SMUL_3125	ENOG4108IJ6	ABC transporter
SMUL_3126	ENOG4105E0C	molybdate abc transporter
SMUL_3128	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
SMUL_3129	ENOG4105F4R	Transcriptional regulator mode
SMUL_3132	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SMUL_3141	ENOG4105C19	ABC transporter
SMUL_3142	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SMUL_3143	ENOG4105BZU	Histidine kinase
SMUL_3146	ENOG4107QY8	reductase
SMUL_3147	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SMUL_3148	ENOG4105CVA	phosphate
SMUL_3149	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
SMUL_3151	ENOG4105EE5	Membrane protein terC
SMUL_3152	ENOG4108XUR	Pfam:DUF178
SMUL_3153	ENOG4105D82	Glutamate dehydrogenase
SMUL_3154	ENOG4105CPD	ethanolamine ammonia-lyase
SMUL_3155	ENOG4107FQ9	ethanolamine ammonia-lyase
SMUL_3156	ENOG4105CUB	amino acid
SMUL_3157	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
SMUL_3158	ENOG4105C6K	Malic enzyme
SMUL_3161	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
SMUL_3162	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
SMUL_3163	ENOG4105DHP	deoxycytidine triphosphate deaminase
SMUL_3168	ENOG4105DR4	Methyltransferase
SMUL_3171	ENOG4105I03	Flagellin
SMUL_3172	ENOG4105C5E	polysaccharide biosynthesis protein
SMUL_3173	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
SMUL_3174	ENOG4105F0R	Cytidylyltransferase
SMUL_3176	ENOG4105D2T	synthase
SMUL_3179	ENOG4105CHR	reductase
SMUL_3180	ENOG4105CEY	Amp-dependent synthetase and ligase
SMUL_3181	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
SMUL_3182	ENOG4105D5D	udp-galactopyranose mutase
SMUL_3184	ENOG4105ECJ	Glycosyl Transferase
SMUL_3185	ENOG4105K64	Glycosyl transferase, family 2
SMUL_3186	ENOG4105EQK	-acetyltransferase
SMUL_3188	ENOG41089UC	methyltransferase, type 11
SMUL_3195	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
SMUL_3196	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
SMUL_3197	ENOG4105BZN	citrate synthase
SMUL_3200	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
SMUL_3201	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
SMUL_3202	ENOG4105E63	Pfam:DUF178
SMUL_3203	ENOG4105VS8	Flagellar biosynthetic protein fliq
SMUL_3204	ENOG4105D4A	Cell wall formation (By similarity)
SMUL_3205	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
SMUL_3207	ENOG4105BZU	Histidine kinase
SMUL_3212	ENOG4105DIN	metallophosphoesterase
SMUL_3213	ENOG4105BZG	amino acid carrier protein
SMUL_3214	ENOG4105C2W	permease
SMUL_3215	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
SMUL_3216	ENOG4105KNE	Phosphatidate cytidylyltransferase
SMUL_3218	ENOG4105F23	Fibronectin-binding protein
SMUL_3219	ENOG4105BZW	Glycerate kinase
SMUL_3220	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
SMUL_3225	ENOG4105D3R	alkyl hydroperoxide reductase
SMUL_3226	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
SMUL_3228	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
SMUL_3229	ENOG41080AZ	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
SMUL_3235	ENOG4105HDD	phospholipase
SMUL_3236	ENOG4105VFU	Rna-binding protein
SMUL_3237	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
SMUL_3240	ENOG4105D5G	Transposase
SMUL_3257	ENOG4105KHC	sulfurtransferase
SMUL_3259	ENOG4105D1F	ATP-binding protein
SMUL_3270	ENOG4105HFZ	Membrane
SMUL_3274	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SMUL_3275	ENOG4108J2R	molybdopterin oxidoreductase
SMUL_3277	ENOG4105DUM	transcriptional regulator, lysR family
SMUL_3281	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SMUL_3282	ENOG4107QY8	reductase
SMUL_3283	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
SMUL_3284	ENOG4105F8J	Adenylate Guanylate cyclase
SMUL_3285	ENOG4105DHT	Metal Dependent Phosphohydrolase
SMUL_3286	ENOG4105NU9	Preprotein translocase subunit SecG
SMUL_3288	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
SMUL_3289	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
SMUL_3294	ENOG4108V0P	LemA family
SMUL_3295	ENOG4105CI3	gtp-binding protein typa
SMUL_3298	ENOG4105BZE	flagellar hook protein, FlgE
SMUL_3299	ENOG4105BZE	flagellar hook protein, FlgE
SMUL_3300	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
SMUL_3301	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)