locus-tag	class	description
FA584_00010	COG1053	succinate dehydrogenase
FA584_00075	COG0745	RESPONSE REGULATOR receiver
FA584_00085	COG0437	4 iron, 4 sulfur cluster binding
FA584_00095	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FA584_00105	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
FA584_00115	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FA584_00125	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FA584_00140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FA584_00145	COG1120	ATPase activity
FA584_00160	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FA584_00205	COG1132	(ABC) transporter
FA584_00210	COG1797	cobyrinic acid a,c-diamide synthase activity
FA584_00220	COG1648	precorrin-2 dehydrogenase activity
FA584_00220	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FA584_00225	COG1309	transcriptional regulator
FA584_00330	COG0582	viral genome integration into host DNA
FA584_00365	COG0582	viral genome integration into host DNA
FA584_00375	COG0776	regulation of translation
FA584_00385	COG1674	ftsk spoiiie
FA584_00385	COG1196	nuclear chromosome segregation
FA584_00390	COG1049	propionate catabolic process, 2-methylcitrate cycle
FA584_00395	COG1047	Peptidyl-prolyl cis-trans
FA584_00400	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FA584_00400	COG0574	Belongs to the PEP-utilizing enzyme family
FA584_00405	COG3713	MltA-interacting MipA family protein
FA584_00415	COG2814	Major facilitator Superfamily
FA584_00435	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FA584_00440	COG0840	transmembrane signaling receptor activity
FA584_00445	COG1832	CoA-binding protein
FA584_00450	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FA584_00460	COG1126	abc transporter atp-binding protein
FA584_00465	COG0765	amino acid transport
FA584_00470	COG4597	amino acid ABC transporter
FA584_00475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FA584_00495	COG0586	Pfam SNARE associated Golgi protein
FA584_00500	COG0577	efflux transmembrane transporter activity
FA584_00500	COG1136	(ABC) transporter
FA584_00505	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FA584_00510	COG0492	ferredoxin-NADP+ reductase activity
FA584_00530	COG0727	PFAM Uncharacterised protein family (UPF0153)
FA584_00540	COG0134	indole-3-glycerol-phosphate synthase activity
FA584_00550	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FA584_00555	COG1122	ATPase activity
FA584_00570	COG0310	cobalt ion transport
FA584_00575	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FA584_00580	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FA584_00595	COG0446	pyridine nucleotide-disulphide oxidoreductase
FA584_00605	COG0028	Belongs to the TPP enzyme family
FA584_00610	COG0440	acetolactate synthase activity
FA584_00615	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FA584_00625	COG0493	'glutamate synthase
FA584_00635	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FA584_00665	COG1045	serine acetyltransferase
FA584_00670	COG1166	arginine decarboxylase activity
FA584_00675	COG0124	histidyl-tRNA synthetase
FA584_00690	COG0163	prenyltransferase activity
FA584_00710	COG0303	'Molybdopterin
FA584_00715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FA584_00730	COG1691	(AIR) carboxylase
FA584_00735	COG1606	tRNA processing
FA584_00740	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
FA584_00745	COG3875	lactate racemase activity
FA584_00750	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FA584_00750	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FA584_00765	COG2205	protein histidine kinase activity
FA584_00765	COG0784	Response regulator, receiver
FA584_00770	COG0745	RESPONSE REGULATOR receiver
FA584_00785	COG0588	phosphoglycerate mutase activity
FA584_00795	COG0582	viral genome integration into host DNA
FA584_00800	COG0343	queuine tRNA-ribosyltransferase activity
FA584_00810	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FA584_00820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FA584_00825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FA584_00845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FA584_00850	COG1187	pseudouridine synthase activity
FA584_00860	COG0028	Belongs to the TPP enzyme family
FA584_00885	COG1981	membrane
FA584_00890	COG1309	transcriptional regulator
FA584_00925	COG0840	transmembrane signaling receptor activity
FA584_00925	COG3290	protein histidine kinase activity
FA584_00930	COG1592	Rubrerythrin
FA584_00940	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FA584_00950	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FA584_00950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FA584_00955	COG3030	protein affecting phage T7 exclusion by the F plasmid
FA584_00960	COG0442	prolyl-tRNA aminoacylation
FA584_00965	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FA584_00970	COG0142	geranyltranstransferase activity
FA584_00990	COG1959	2 iron, 2 sulfur cluster binding
FA584_01000	COG3706	GGDEF domain
FA584_01005	COG0525	valine-tRNA ligase activity
FA584_01010	COG0521	Mo-molybdopterin cofactor biosynthetic process
FA584_01015	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FA584_01020	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FA584_01040	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FA584_01050	COG2195	Cleaves the N-terminal amino acid of tripeptides
FA584_01075	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FA584_01080	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FA584_01085	COG1663	tetraacyldisaccharide 4'-kinase activity
FA584_01090	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FA584_01095	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FA584_01100	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FA584_01105	COG4232	protein-disulfide reductase activity
FA584_01115	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FA584_01120	COG0443	Heat shock 70 kDa protein
FA584_01125	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FA584_01130	COG1420	regulation of RNA biosynthetic process
FA584_01140	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FA584_01145	COG1959	2 iron, 2 sulfur cluster binding
FA584_01150	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FA584_01155	COG2404	hydrolase activity, acting on ester bonds
FA584_01165	COG2226	methyltransferase
FA584_01175	COG0196	riboflavin kinase activity
FA584_01185	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FA584_01190	COG0730	response to heat
FA584_01200	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FA584_01215	COG0527	aspartate kinase activity
FA584_01220	COG0494	nUDIX hydrolase
FA584_01225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FA584_01235	COG0789	Transcriptional regulator
FA584_01240	COG0484	heat shock protein binding
FA584_01250	COG0745	RESPONSE REGULATOR receiver
FA584_01255	COG0642	Histidine kinase
FA584_01270	COG0653	protein targeting
FA584_01275	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FA584_01285	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FA584_01290	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FA584_01300	COG0706	membrane insertase activity
FA584_01305	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FA584_01310	COG0594	ribonuclease P activity
FA584_01315	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FA584_01330	COG4865	methylaspartate mutase activity
FA584_01345	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FA584_01360	COG0542	response to heat
FA584_01365	COG0793	Belongs to the peptidase S41A family
FA584_01370	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FA584_01375	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FA584_01380	COG0047	phosphoribosylformylglycinamidine synthase activity
FA584_01390	COG0204	Acyl-transferase
FA584_01395	COG0326	Molecular chaperone. Has ATPase activity
FA584_01415	COG1331	Highly conserved protein containing a thioredoxin domain
FA584_01420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FA584_01455	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FA584_01475	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FA584_01485	COG2608	mercury ion transmembrane transporter activity
FA584_01490	COG2217	Heavy metal translocating P-type atpase
FA584_01495	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FA584_01510	COG0275	rRNA processing
FA584_01520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FA584_01525	COG0849	cell division
FA584_01530	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FA584_01540	COG2890	protein-(glutamine-N5) methyltransferase activity
FA584_01540	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FA584_01545	COG0501	Belongs to the peptidase M48B family
FA584_01555	COG0488	(ABC) transporter
FA584_01560	COG0840	transmembrane signaling receptor activity
FA584_01570	COG2151	metal-sulfur cluster biosynthetic enzyme
FA584_01585	COG0138	bifunctional purine biosynthesis protein purh
FA584_01590	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FA584_01600	COG1607	acyl-coa hydrolase
FA584_01605	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FA584_01610	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FA584_01635	COG0842	Transport permease protein
FA584_01640	COG0842	Transport permease protein
FA584_01650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FA584_01655	COG1309	transcriptional regulator
FA584_01665	COG3328	transposase activity
FA584_01670	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FA584_01680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FA584_01685	COG0805	protein transport
FA584_01690	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FA584_01715	COG3437	response regulator, receiver
FA584_01725	COG2205	protein histidine kinase activity
FA584_01725	COG3437	response regulator, receiver
FA584_01725	COG3850	Histidine kinase
FA584_01725	COG4999	Histidine kinase
FA584_01730	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FA584_01750	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FA584_01755	COG0569	domain protein
FA584_01760	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FA584_01775	COG2068	MobA-Related Protein
FA584_01780	COG3608	succinylglutamate desuccinylase aspartoacylase
FA584_01780	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FA584_01785	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FA584_01800	COG2226	methyltransferase
FA584_01820	COG2205	protein histidine kinase activity
FA584_01820	COG2198	Histidine kinase
FA584_01820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FA584_01820	COG0784	Response regulator, receiver
FA584_01850	COG0646	methionine synthase
FA584_01850	COG1410	methionine synthase
FA584_01865	COG0840	transmembrane signaling receptor activity
FA584_01870	COG1280	lysine exporter protein (LysE YggA)
FA584_01890	COG0004	ammonium transporteR
FA584_01895	COG0347	Belongs to the P(II) protein family
FA584_01915	COG0751	glycine-tRNA ligase activity
FA584_01930	COG0288	reversible hydration of carbon dioxide
FA584_01935	COG3123	guanosine phosphorylase activity
FA584_01945	COG2081	HI0933 family
FA584_01955	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FA584_01960	COG0788	formyltetrahydrofolate deformylase activity
FA584_01965	COG0617	tRNA 3'-terminal CCA addition
FA584_01980	COG0473	3-isopropylmalate dehydrogenase activity
FA584_01985	COG0066	3-isopropylmalate dehydratase activity
FA584_02020	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FA584_02035	COG0708	Exodeoxyribonuclease III
FA584_02055	COG2816	NAD+ diphosphatase activity
FA584_02060	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FA584_02065	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FA584_02070	COG4319	ketosteroid isomerase
FA584_02085	COG0840	transmembrane signaling receptor activity
FA584_02095	COG4977	sequence-specific DNA binding
FA584_02100	COG0431	NADPH-dependent FMN reductase
FA584_02105	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FA584_02110	COG3706	GGDEF domain
FA584_02120	COG4895	conserved protein (DUF2196)
FA584_02140	COG0513	Belongs to the DEAD box helicase family
FA584_02150	COG0642	Histidine kinase
FA584_02155	COG0745	RESPONSE REGULATOR receiver
FA584_02195	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FA584_02200	COG0372	Belongs to the citrate synthase family
FA584_02205	COG2079	MmgE PrpD family protein
FA584_02215	COG2824	Alkylphosphonate utilization operon protein PhnA
FA584_02225	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FA584_02235	COG4786	Flagellar basal body rod
FA584_02240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FA584_02250	COG1733	regulation of RNA biosynthetic process
FA584_02265	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FA584_02270	COG1121	(ABC) transporter
FA584_02275	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FA584_02295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FA584_02300	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FA584_02305	COG3162	membrane
FA584_02310	COG0745	RESPONSE REGULATOR receiver
FA584_02315	COG0642	Histidine kinase
FA584_02330	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FA584_02335	COG1918	ferrous iron import across plasma membrane
FA584_02365	COG3585	molybdate ion transport
FA584_02375	COG0598	Magnesium transport protein CorA
FA584_02380	COG0739	heme binding
FA584_02390	COG0277	FAD linked oxidase domain protein
FA584_02395	COG1295	ribonuclease BN
FA584_02405	COG0305	Participates in initiation and elongation during chromosome replication
FA584_02410	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FA584_02415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FA584_02440	COG0556	nucleotide-excision repair
FA584_02450	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FA584_02455	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FA584_02460	COG2176	DNA-directed DNA polymerase activity
FA584_02465	COG0135	phosphoribosylanthranilate isomerase activity
FA584_02470	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FA584_02480	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FA584_02495	COG1692	metallophosphoesterase
FA584_02500	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FA584_02510	COG0739	heme binding
FA584_02515	COG0285	dihydrofolate synthase activity
FA584_02530	COG0495	leucyl-tRNA aminoacylation
FA584_02535	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FA584_02540	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FA584_02545	COG1862	Preprotein translocase
FA584_02550	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FA584_02555	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FA584_02565	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FA584_02575	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FA584_02585	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FA584_02590	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FA584_02595	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FA584_02600	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FA584_02605	COG0210	DNA helicase
FA584_02635	COG0540	Belongs to the ATCase OTCase family
FA584_02645	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FA584_02685	COG0228	four-way junction DNA binding
FA584_02690	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FA584_02695	COG0564	pseudouridine synthase activity
FA584_02700	COG1519	Transferase
FA584_02710	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FA584_02715	COG0752	glycyl-tRNA synthetase alpha subunit
FA584_02725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FA584_02730	COG0826	peptidase U32
FA584_02740	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FA584_02745	COG0174	glutamine synthetase
FA584_02755	COG4172	Belongs to the ABC transporter superfamily
FA584_02760	COG0156	8-amino-7-oxononanoate synthase activity
FA584_02765	COG0424	maF-like protein
FA584_02775	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FA584_02800	COG1028	Short-chain dehydrogenase reductase Sdr
FA584_02815	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FA584_02820	COG0768	penicillin binding
FA584_02830	COG1558	bacterial-type flagellum-dependent cell motility
FA584_02835	COG1815	bacterial-type flagellum-dependent cell motility
FA584_02840	COG0772	Belongs to the SEDS family
FA584_02845	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FA584_02950	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FA584_02960	COG0697	spore germination
FA584_03025	COG0512	Glutamine amidotransferase of anthranilate synthase
FA584_03040	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FA584_03050	COG1518	maintenance of DNA repeat elements
FA584_03180	COG0330	HflC and HflK could
FA584_03205	COG2814	Major facilitator Superfamily
FA584_03215	COG0640	Transcriptional regulator
FA584_03235	COG2301	Belongs to the HpcH HpaI aldolase family
FA584_03240	COG3052	prosthetic group binding
FA584_03255	COG2814	Major facilitator Superfamily
FA584_03265	COG2252	PERMEase
FA584_03270	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FA584_03280	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FA584_03290	COG0133	tryptophan synthase activity
FA584_03300	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FA584_03305	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FA584_03310	COG3706	GGDEF domain
FA584_03330	COG2200	EAL domain
FA584_03330	COG2199	diguanylate cyclase activity
FA584_03330	COG2202	Pas domain
FA584_03340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FA584_03360	COG0488	(ABC) transporter
FA584_03370	COG0745	RESPONSE REGULATOR receiver
FA584_03385	COG1151	hydroxylamine reductase activity
FA584_03395	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FA584_03405	COG0650	Formate hydrogenlyase subunit 4
FA584_03410	COG4237	Hydrogenase 4 membrane
FA584_03415	COG0651	ATP synthesis coupled electron transport
FA584_03420	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FA584_03420	COG3261	NADH dehydrogenase
FA584_03430	COG3260	NADH ubiquinone oxidoreductase 20
FA584_03465	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FA584_03480	COG2171	N-acyltransferase activity
FA584_03485	COG0489	protein tyrosine kinase activity
FA584_03490	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FA584_03490	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FA584_03500	COG2046	Belongs to the sulfate adenylyltransferase family
FA584_03510	COG2353	YceI-like domain
FA584_03515	COG1739	Uncharacterized protein family UPF0029
FA584_03520	COG0157	Belongs to the NadC ModD family
FA584_03535	COG3842	ATPase activity
FA584_03560	COG1686	Belongs to the peptidase S11 family
FA584_03565	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FA584_03570	COG0577	efflux transmembrane transporter activity
FA584_03570	COG1136	(ABC) transporter
FA584_03575	COG1136	(ABC) transporter
FA584_03600	COG0668	transmembrane transport
FA584_03605	COG3300	MHYT domain
FA584_03605	COG5001	Diguanylate cyclase
FA584_03620	COG3645	SOS response
FA584_03730	COG0284	orotidine-5'-phosphate decarboxylase activity
FA584_03735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FA584_03740	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FA584_03750	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FA584_03755	COG0697	spore germination
FA584_03760	COG0668	transmembrane transport
FA584_03765	COG1160	GTP binding
FA584_03780	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FA584_03790	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FA584_03795	COG1183	phosphatidylcholine synthase activity
FA584_03805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FA584_03810	COG2264	protein methyltransferase activity
FA584_03815	COG0745	RESPONSE REGULATOR receiver
FA584_03820	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FA584_03825	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FA584_03845	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FA584_03860	COG1442	glycosyl transferase family 8
FA584_03860	COG1216	Glycosyl transferase, family 2
FA584_03870	COG0110	maltose O-acetyltransferase activity
FA584_03895	COG0028	Belongs to the TPP enzyme family
FA584_03905	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FA584_03920	COG1793	dna ligase
FA584_03930	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FA584_03935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FA584_03960	COG0859	PFAM glycosyl transferase family 9
FA584_03980	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FA584_03985	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FA584_03985	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FA584_03990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FA584_04015	COG2217	Heavy metal translocating P-type atpase
FA584_04025	COG0697	spore germination
FA584_04040	COG2199	diguanylate cyclase activity
FA584_04055	COG1496	oxidoreductase activity
FA584_04065	COG0840	transmembrane signaling receptor activity
FA584_04070	COG1984	allophanate hydrolase subunit 2
FA584_04080	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FA584_04085	COG0445	tRNA wobble uridine modification
FA584_04090	COG0723	plastoquinol--plastocyanin reductase activity
FA584_04095	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FA584_04100	COG2857	Cytochrome c1
FA584_04110	COG0825	malonyl-CoA metabolic process
FA584_04115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FA584_04120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FA584_04130	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FA584_04135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FA584_04140	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FA584_04165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FA584_04170	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FA584_04190	COG0463	Glycosyl transferase, family 2
FA584_04205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FA584_04210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FA584_04235	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FA584_04260	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FA584_04260	COG0662	Cupin 2, conserved barrel domain protein
FA584_04265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FA584_04290	COG0745	RESPONSE REGULATOR receiver
FA584_04305	COG0398	Pfam SNARE associated Golgi protein
FA584_04310	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FA584_04325	COG0390	transport system, permease component
FA584_04330	COG0439	Biotin carboxylase
FA584_04345	COG0513	Belongs to the DEAD box helicase family
FA584_04350	COG1671	Belongs to the UPF0178 family
FA584_04355	COG0667	Aldo Keto reductase
FA584_04360	COG2814	Major facilitator Superfamily
FA584_04365	COG2207	Transcriptional regulator
FA584_04385	COG0573	inorganic phosphate transmembrane transporter activity
FA584_04395	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FA584_04405	COG3384	dioxygenase
FA584_04425	COG0745	RESPONSE REGULATOR receiver
FA584_04435	COG1607	acyl-coa hydrolase
FA584_04455	COG1733	regulation of RNA biosynthetic process
FA584_04460	COG2249	NAD(P)H dehydrogenase (quinone) activity
FA584_04465	COG3852	Histidine kinase
FA584_04470	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FA584_04475	COG0602	queuosine metabolic process
FA584_04505	COG1702	phosphate starvation-inducible protein PhoH
FA584_04515	COG2814	Major facilitator Superfamily
FA584_04520	COG0477	Major facilitator Superfamily
FA584_04530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FA584_04550	COG3787	Belongs to the UPF0306 family
FA584_04555	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FA584_04585	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FA584_04585	COG0674	pyruvate-flavodoxin oxidoreductase activity
FA584_04585	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FA584_04585	COG1013	pyruvate-flavodoxin oxidoreductase activity
FA584_04595	COG0471	metal ion transport
FA584_04605	COG0668	transmembrane transport
FA584_04610	COG2885	chlorophyll binding
FA584_04610	COG3047	cAMP biosynthetic process
FA584_04620	COG1881	PFAM PEBP family protein
FA584_04625	COG2207	Transcriptional regulator
FA584_04630	COG0519	Catalyzes the synthesis of GMP from XMP
FA584_04650	COG1979	alcohol dehydrogenase
FA584_04660	COG0038	chloride channel
FA584_04665	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FA584_04680	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FA584_04685	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FA584_04690	COG1074	ATP-dependent DNA helicase activity
FA584_04730	COG3278	Belongs to the heme-copper respiratory oxidase family
FA584_04735	COG0745	RESPONSE REGULATOR receiver
FA584_04750	COG0505	Belongs to the CarA family
FA584_04770	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FA584_04775	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FA584_04780	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FA584_04790	COG0840	transmembrane signaling receptor activity
FA584_04795	COG0546	phosphoglycolate phosphatase activity
FA584_04810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FA584_04815	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FA584_04820	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FA584_04825	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FA584_04840	COG0203	ribosomal protein L17
FA584_04850	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FA584_04855	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FA584_04860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FA584_04865	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FA584_04875	COG0024	Methionine aminopeptidase
FA584_04880	COG0201	protein transport
FA584_04885	COG0200	Binds to the 23S rRNA
FA584_04890	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FA584_04895	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FA584_04900	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FA584_04905	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FA584_04910	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FA584_04920	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FA584_04925	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FA584_04930	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FA584_04935	COG0255	Belongs to the universal ribosomal protein uL29 family
FA584_04940	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FA584_04945	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FA584_04955	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FA584_04960	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FA584_04965	COG0089	rRNA binding
FA584_04970	COG0088	Forms part of the polypeptide exit tunnel
FA584_04975	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FA584_04980	COG0051	transcription antitermination factor activity, RNA binding
FA584_04995	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FA584_05000	COG0672	)-iron permease
FA584_05025	COG0577	efflux transmembrane transporter activity
FA584_05025	COG1136	(ABC) transporter
FA584_05045	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FA584_05050	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FA584_05055	COG0571	ribonuclease III activity
FA584_05060	COG0328	RNA-DNA hybrid ribonuclease activity
FA584_05070	COG0358	DNA primase activity
FA584_05075	COG0137	argininosuccinate synthase activity
FA584_05080	COG2201	protein-glutamate methylesterase activity
FA584_05100	COG2205	protein histidine kinase activity
FA584_05105	COG2201	protein-glutamate methylesterase activity
FA584_05110	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FA584_05145	COG0643	Histidine kinase
FA584_05145	COG2198	Histidine kinase
FA584_05155	COG0840	transmembrane signaling receptor activity
FA584_05160	COG0835	chemotaxis
FA584_05165	COG0745	RESPONSE REGULATOR receiver
FA584_05195	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FA584_05200	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FA584_05220	COG1280	lysine exporter protein (LysE YggA)
FA584_05225	COG1090	epimerase
FA584_05265	COG2199	diguanylate cyclase activity
FA584_05270	COG2962	Rard protein
FA584_05280	COG5002	protein histidine kinase activity
FA584_05280	COG3850	Histidine kinase
FA584_05285	COG2194	sulfuric ester hydrolase activity
FA584_05295	COG2200	EAL domain
FA584_05310	COG1968	undecaprenyl-diphosphatase activity
FA584_05315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FA584_05320	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
FA584_05330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FA584_05345	COG1027	Aspartate ammonia-lyase
FA584_05350	COG1027	Aspartate ammonia-lyase
FA584_05355	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FA584_05360	COG0252	asparaginase activity
FA584_05365	COG4191	Histidine kinase
FA584_05370	COG0745	RESPONSE REGULATOR receiver
FA584_05375	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FA584_05385	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FA584_05390	COG0804	urea catabolic process
FA584_05395	COG0831	urea catabolic process
FA584_05395	COG0832	Belongs to the urease beta subunit family
FA584_05400	COG0829	nickel cation binding
FA584_05430	COG0784	Response regulator, receiver
FA584_05430	COG2205	protein histidine kinase activity
FA584_05435	COG0745	RESPONSE REGULATOR receiver
FA584_05450	COG0714	Associated with various cellular activities
FA584_05490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FA584_05495	COG0765	amino acid transport
FA584_05525	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FA584_05530	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FA584_05565	COG0709	Synthesizes selenophosphate from selenide and ATP
FA584_05570	COG0425	Belongs to the sulfur carrier protein TusA family
FA584_05580	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FA584_05585	COG3447	MASE1 domain protein
FA584_05585	COG5002	protein histidine kinase activity
FA584_05585	COG5001	Diguanylate cyclase
FA584_05595	COG2814	Major facilitator Superfamily
FA584_05620	COG3839	Belongs to the ABC transporter superfamily
FA584_05625	COG4662	Binding-protein-dependent transport system inner membrane component
FA584_05630	COG2998	abc-type tungstate transport system, permease component
FA584_05650	COG0437	4 iron, 4 sulfur cluster binding
FA584_05675	COG1120	ATPase activity
FA584_05680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FA584_05685	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FA584_05690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FA584_05710	COG0848	biopolymer transport protein
FA584_05715	COG0811	peptide transport
FA584_05745	COG0500	methyltransferase
FA584_05755	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FA584_05760	COG4208	sulfate ABC transporter
FA584_05765	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FA584_05770	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FA584_05775	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FA584_05810	COG0437	4 iron, 4 sulfur cluster binding
FA584_05840	COG2205	protein histidine kinase activity
FA584_05850	COG1921	L-seryl-tRNASec selenium transferase activity
FA584_05875	COG1741	Belongs to the pirin family
FA584_05910	COG0745	RESPONSE REGULATOR receiver
FA584_05915	COG0642	Histidine kinase
FA584_05925	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FA584_05930	COG0463	Glycosyl transferase, family 2
FA584_05940	COG1028	Short-chain dehydrogenase reductase Sdr
FA584_05995	COG0513	Belongs to the DEAD box helicase family
FA584_06025	COG1305	Transglutaminase-like
FA584_06040	COG0745	RESPONSE REGULATOR receiver
FA584_06060	COG0439	Biotin carboxylase
FA584_06075	COG1116	anion transmembrane transporter activity
FA584_06080	COG2011	ABC-type metal ion transport system permease component
FA584_06090	COG0642	Histidine kinase
FA584_06095	COG0745	RESPONSE REGULATOR receiver
FA584_06130	COG0300	oxidoreductase activity
FA584_06145	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FA584_06155	COG2814	Major facilitator Superfamily
FA584_06160	COG1238	metal cluster binding
FA584_06175	COG0471	metal ion transport
FA584_06180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FA584_06190	COG0303	'Molybdopterin
FA584_06195	COG0314	molybdopterin synthase activity
FA584_06215	COG1157	protein secretion by the type III secretion system
FA584_06220	COG0302	gtp cyclohydrolase
FA584_06225	COG0544	peptidyl-prolyl cis-trans isomerase activity
FA584_06230	COG0740	serine-type endopeptidase activity
FA584_06245	COG0606	chelatase, subunit chli
FA584_06250	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FA584_06250	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FA584_06260	COG2022	thiamine diphosphate biosynthetic process
FA584_06290	COG0582	viral genome integration into host DNA
FA584_06365	COG3437	response regulator, receiver
FA584_06365	COG0784	Response regulator, receiver
FA584_06405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FA584_06410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FA584_06425	COG0463	Glycosyl transferase, family 2
FA584_06440	COG0671	phosphoesterase, PA-phosphatase related
FA584_06455	COG1012	belongs to the aldehyde dehydrogenase family
FA584_06470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FA584_06495	COG0840	transmembrane signaling receptor activity
FA584_06500	COG2183	response to ionizing radiation
FA584_06520	COG0842	Transport permease protein
FA584_06525	COG0842	Transport permease protein
FA584_06530	COG1131	(ABC) transporter
FA584_06535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FA584_06545	COG0778	Nitroreductase
FA584_06590	COG0577	efflux transmembrane transporter activity
FA584_06595	COG1136	(ABC) transporter
FA584_06605	COG1472	Belongs to the glycosyl hydrolase 3 family
FA584_06635	COG0431	NADPH-dependent FMN reductase
FA584_06645	COG0300	oxidoreductase activity
FA584_06655	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FA584_06660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FA584_06690	COG0745	RESPONSE REGULATOR receiver
FA584_06695	COG0642	Histidine kinase
FA584_06705	COG0175	sulfate reduction
FA584_06710	COG0175	sulfate reduction
FA584_06715	COG2895	sulfate adenylyltransferase (ATP) activity
FA584_06725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FA584_06735	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FA584_06740	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FA584_06740	COG1648	precorrin-2 dehydrogenase activity
FA584_06745	COG0626	cystathionine gamma-synthase activity
FA584_06755	COG0482	sulfurtransferase activity
FA584_06775	COG3706	GGDEF domain
FA584_06785	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FA584_06795	COG0861	Integral membrane protein TerC family
FA584_06800	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FA584_06805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FA584_06810	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FA584_06815	COG0281	malic enzyme
FA584_06815	COG0280	phosphate acetyltransferase
FA584_06820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FA584_06830	COG0439	Biotin carboxylase
FA584_06835	COG0511	ligase activity, forming carbon-carbon bonds
FA584_06840	COG0717	Belongs to the dCTP deaminase family
FA584_06860	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FA584_06865	COG1073	alpha beta
FA584_06880	COG1086	Polysaccharide biosynthesis protein
FA584_06885	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FA584_06890	COG1083	cytidylyl-transferase
FA584_06900	COG2226	methyltransferase
FA584_06905	COG2089	acid synthase
FA584_06910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FA584_06940	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FA584_06945	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FA584_06950	COG0372	Belongs to the citrate synthase family
FA584_06965	COG0148	phosphopyruvate hydratase activity
FA584_06970	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FA584_06975	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FA584_06985	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FA584_06995	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FA584_07025	COG1408	metallophosphoesterase
FA584_07030	COG1115	amino acid carrier protein
FA584_07035	COG2233	PERMEase
FA584_07040	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FA584_07045	COG0575	Belongs to the CDS family
FA584_07060	COG1929	Belongs to the glycerate kinase type-1 family
FA584_07080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FA584_07090	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FA584_07095	COG0746	molybdenum cofactor guanylyltransferase activity
FA584_07130	COG0315	cyclic pyranopterin monophosphate synthase activity
FA584_07135	COG2921	Belongs to the UPF0250 family
FA584_07195	COG0670	Belongs to the BI1 family
FA584_07210	COG0437	4 iron, 4 sulfur cluster binding
FA584_07215	COG0243	molybdopterin cofactor binding
FA584_07220	COG4106	trans-aconitate 2-methyltransferase activity
FA584_07240	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FA584_07245	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FA584_07255	COG0233	cytoplasmic translational termination
FA584_07260	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FA584_07285	COG1704	LemA family
FA584_07290	COG1217	gtp-binding protein TYPA
FA584_07300	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FA584_07305	COG1749	Flagellar hook protein flgE
FA584_07310	COG1749	Flagellar hook protein flgE
FA584_07315	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FA584_07320	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FA584_07330	COG0592	DNA-directed DNA polymerase activity
FA584_07335	COG0187	DNA topoisomerase II activity
FA584_07340	COG5001	Diguanylate cyclase
FA584_07345	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FA584_07360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FA584_07365	COG1194	a g-specific adenine glycosylase
FA584_07370	COG2814	Major facilitator Superfamily
FA584_07385	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FA584_07395	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FA584_07400	COG0066	3-isopropylmalate dehydratase activity
FA584_07450	COG0840	transmembrane signaling receptor activity
FA584_07470	COG1335	isochorismatase
FA584_07490	COG3708	Transcriptional regulator
FA584_07490	COG2207	Transcriptional regulator
FA584_07500	COG1355	regulation of microtubule-based process
FA584_07510	COG2078	PFAM AMMECR1 domain protein
FA584_07545	COG3150	esterase
FA584_07555	COG3383	formate dehydrogenase (NAD+) activity
FA584_07585	COG0129	dihydroxy-acid dehydratase activity
FA584_07590	COG2095	MarC family integral membrane protein
FA584_07615	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FA584_07620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FA584_07625	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FA584_07640	COG1328	CTP reductase activity
FA584_07640	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FA584_07645	COG1794	racemase activity, acting on amino acids and derivatives
FA584_07650	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FA584_07655	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FA584_07660	COG0564	pseudouridine synthase activity
FA584_07665	COG0179	Fumarylacetoacetate (FAA) hydrolase
FA584_07670	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FA584_07680	COG0107	imidazoleglycerol-phosphate synthase activity
FA584_07690	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FA584_07695	COG0517	IMP dehydrogenase activity
FA584_07695	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FA584_07700	COG1187	pseudouridine synthase activity
FA584_07705	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FA584_07705	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FA584_07715	COG2257	FlhB HrpN YscU SpaS Family
FA584_07735	COG0237	dephospho-CoA kinase activity
FA584_07740	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FA584_07750	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FA584_07755	COG0268	Binds directly to 16S ribosomal RNA
FA584_07760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FA584_07765	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FA584_07775	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FA584_07780	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FA584_07785	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FA584_07790	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FA584_07795	COG0348	domain, Protein
FA584_07805	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FA584_07820	COG0754	glutathionylspermidine amidase activity
FA584_07825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FA584_07870	COG0642	Histidine kinase
FA584_07875	COG0745	RESPONSE REGULATOR receiver
FA584_07895	COG1127	ABC transporter
FA584_07900	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FA584_07915	COG2095	MarC family integral membrane protein
FA584_07920	COG0840	transmembrane signaling receptor activity
FA584_07940	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FA584_07950	COG5002	protein histidine kinase activity
FA584_07960	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FA584_07970	COG0004	ammonium transporteR
FA584_07975	COG0667	Aldo Keto reductase
FA584_07985	COG0745	RESPONSE REGULATOR receiver
FA584_08025	COG0765	amino acid transport
FA584_08065	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FA584_08075	COG0318	PFAM AMP-dependent synthetase and ligase
FA584_08080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FA584_08085	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA584_08090	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA584_08095	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA584_08100	COG0649	NAD binding
FA584_08120	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FA584_08125	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA584_08130	COG0839	Belongs to the complex I subunit 6 family
FA584_08135	COG0713	ATP synthesis coupled electron transport
FA584_08140	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FA584_08150	COG1007	ATP synthesis coupled electron transport
FA584_08160	COG1012	belongs to the aldehyde dehydrogenase family
FA584_08165	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FA584_08170	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FA584_08185	COG0840	transmembrane signaling receptor activity
FA584_08190	COG0840	transmembrane signaling receptor activity
FA584_08195	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FA584_08200	COG0303	'Molybdopterin
FA584_08210	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FA584_08215	COG0254	rRNA binding
FA584_08220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FA584_08225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FA584_08240	COG0436	Aminotransferase
FA584_08245	COG0460	homoserine dehydrogenase
FA584_08250	COG0792	nuclease activity
FA584_08255	COG3118	belongs to the thioredoxin family
FA584_08260	COG0492	ferredoxin-NADP+ reductase activity
FA584_08265	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FA584_08270	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FA584_08275	COG1242	4 iron, 4 sulfur cluster binding
FA584_08290	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FA584_08290	COG0140	phosphoribosyl-ATP diphosphatase activity
FA584_08305	COG1012	belongs to the aldehyde dehydrogenase family
FA584_08310	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FA584_08325	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FA584_08330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FA584_08335	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FA584_08340	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FA584_08355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FA584_08375	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FA584_08380	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FA584_08385	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FA584_08390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FA584_08395	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FA584_08405	COG0784	Response regulator, receiver
FA584_08405	COG0835	chemotaxis
FA584_08410	COG0643	Histidine kinase
FA584_08410	COG0784	Response regulator, receiver
FA584_08410	COG2198	Histidine kinase
FA584_08415	COG0835	chemotaxis
FA584_08430	COG0560	Phosphoserine phosphatase
FA584_08450	COG0193	aminoacyl-tRNA hydrolase activity
FA584_08460	COG0019	diaminopimelate decarboxylase activity
FA584_08465	COG1605	Chorismate mutase
FA584_08465	COG0077	Prephenate dehydratase
FA584_08470	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FA584_08480	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FA584_08490	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FA584_08495	COG0735	belongs to the Fur family
FA584_08500	COG0450	alkyl hydroperoxide reductase
FA584_08515	COG0105	UTP biosynthetic process
FA584_08525	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FA584_08530	COG0416	fatty acid biosynthetic process
FA584_08535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FA584_08540	COG0714	Associated with various cellular activities
FA584_08560	COG2304	oxidoreductase activity
FA584_08570	COG0287	Prephenate dehydrogenase
FA584_08575	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FA584_08585	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FA584_08595	COG0745	RESPONSE REGULATOR receiver
FA584_08605	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FA584_08615	COG0157	Belongs to the NadC ModD family
FA584_08620	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FA584_08635	COG0850	regulation of cytokinetic process
FA584_08640	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FA584_08650	COG0083	homoserine kinase activity
FA584_08660	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FA584_08670	COG0779	Required for maturation of 30S ribosomal subunits
FA584_08675	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FA584_08675	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FA584_08690	COG5001	Diguanylate cyclase
FA584_08700	COG5002	protein histidine kinase activity
FA584_08730	COG3258	Cytochrome c
FA584_08740	COG1242	4 iron, 4 sulfur cluster binding
FA584_08745	COG0243	molybdopterin cofactor binding
FA584_08750	COG0437	4 iron, 4 sulfur cluster binding
FA584_08755	COG3301	Polysulphide reductase, NrfD
FA584_08760	COG2200	EAL domain
FA584_08760	COG3287	FIST C domain
FA584_08760	COG2199	diguanylate cyclase activity
FA584_08770	COG0437	4 iron, 4 sulfur cluster binding
FA584_08775	COG3301	Polysulphide reductase, NrfD
FA584_08780	COG0745	RESPONSE REGULATOR receiver
FA584_08785	COG5002	protein histidine kinase activity
FA584_08795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FA584_08820	COG0848	biopolymer transport protein
FA584_08825	COG0811	peptide transport
FA584_08830	COG1227	inorganic diphosphatase activity
FA584_08850	COG1570	exodeoxyribonuclease VII activity
FA584_08865	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FA584_08885	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FA584_08895	COG2207	Transcriptional regulator
FA584_08900	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FA584_08905	COG0583	DNA-binding transcription factor activity
FA584_08910	COG2855	membrane
FA584_08915	COG0386	Belongs to the glutathione peroxidase family
FA584_08920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FA584_08930	COG0402	S-adenosylhomocysteine deaminase activity
FA584_08935	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FA584_08940	COG0006	proline dipeptidase activity
FA584_08945	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FA584_08950	COG1419	protein localization to endoplasmic reticulum
FA584_08955	COG0455	bacterial-type flagellum organization
FA584_08965	COG1191	sigma factor activity
FA584_08970	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FA584_08975	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FA584_08975	COG1776	CheC inhibitor of MCP methylation
FA584_08990	COG0463	Glycosyl transferase, family 2
FA584_09000	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FA584_09020	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FA584_09030	COG1040	competence protein
FA584_09065	COG2204	response regulator
FA584_09070	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FA584_09080	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FA584_09085	COG0731	radical SAM domain protein
FA584_09095	COG2358	TRAP transporter, solute receptor (TAXI family
FA584_09105	COG0582	viral genome integration into host DNA
FA584_09110	COG1002	Type II restriction enzyme, methylase subunits
FA584_09130	COG3177	Filamentation induced by cAMP protein fic
FA584_09135	COG1061	Type III restriction enzyme res subunit
FA584_09140	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FA584_09190	COG1464	Belongs to the NlpA lipoprotein family
FA584_09195	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FA584_09200	COG2011	ABC-type metal ion transport system permease component
FA584_09205	COG0306	phosphate transporter
FA584_09210	COG0039	L-malate dehydrogenase activity
FA584_09215	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FA584_09270	COG3118	belongs to the thioredoxin family
FA584_09280	COG4336	lyase activity
FA584_09305	COG4628	conserved protein (DUF2132)
FA584_09310	COG4221	oxidoreductase activity
FA584_09315	COG0683	leucine binding
FA584_09345	COG3022	response to hydroperoxide
FA584_09370	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FA584_09375	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FA584_09390	COG0250	Participates in transcription elongation, termination and antitermination
FA584_09395	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FA584_09400	COG0081	regulation of translation
FA584_09405	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FA584_09410	COG0222	ribosome binding
FA584_09415	COG0085	RNA polymerase activity
FA584_09420	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FA584_09425	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FA584_09435	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FA584_09445	COG0697	spore germination
FA584_09450	COG0656	L-ascorbic acid biosynthetic process
FA584_09460	COG0471	metal ion transport
FA584_09465	COG0534	Mate efflux family protein
FA584_09480	COG0745	RESPONSE REGULATOR receiver
FA584_09485	COG0747	negative chemotaxis
FA584_09495	COG0840	transmembrane signaling receptor activity
FA584_09500	COG0840	transmembrane signaling receptor activity
FA584_09510	COG1034	ATP synthesis coupled electron transport
FA584_09515	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FA584_09520	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA584_09525	COG0839	Belongs to the complex I subunit 6 family
FA584_09530	COG0713	ATP synthesis coupled electron transport
FA584_09535	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FA584_09540	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA584_09545	COG1007	ATP synthesis coupled electron transport
FA584_09570	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FA584_09575	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA584_09575	COG0649	NAD binding
FA584_09580	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA584_09585	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA584_09600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FA584_09620	COG0357	Ribosomal RNA small subunit methyltransferase G
FA584_09635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FA584_09640	COG1970	mechanosensitive ion channel activity
FA584_09650	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FA584_09655	COG0113	porphobilinogen synthase activity
FA584_09660	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FA584_09675	COG0247	lactate metabolic process
FA584_09690	COG3012	SEC-C Motif Domain Protein
FA584_09705	COG3706	GGDEF domain
FA584_09710	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FA584_09720	COG1053	succinate dehydrogenase
FA584_09725	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FA584_09735	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FA584_09740	COG0628	permease
FA584_09745	COG2255	four-way junction helicase activity
FA584_09750	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FA584_09760	COG0159	tryptophan synthase activity
FA584_09780	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FA584_09785	COG1136	(ABC) transporter
FA584_09790	COG1684	flagellar biosynthetic protein fliR
FA584_09800	COG0194	GDP metabolic process
FA584_09805	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FA584_09810	COG0018	arginyl-trna synthetase
FA584_09820	COG2199	diguanylate cyclase activity
FA584_09820	COG2200	EAL domain
FA584_09820	COG3287	FIST C domain
FA584_09855	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FA584_09860	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FA584_09870	COG0149	triose-phosphate isomerase activity
FA584_09875	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FA584_09880	COG4174	ABC transporter (Permease)
FA584_09885	COG0195	Participates in both transcription termination and antitermination
FA584_09920	COG0037	tRNA processing
FA584_09925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FA584_09930	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FA584_09935	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FA584_09960	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FA584_09965	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FA584_09970	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FA584_09980	COG1151	hydroxylamine reductase activity
FA584_09985	COG3040	lipid binding
FA584_10000	COG2326	polyphosphate kinase activity
FA584_10015	COG0723	plastoquinol--plastocyanin reductase activity
FA584_10020	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FA584_10030	COG1981	membrane
FA584_10035	COG0513	Belongs to the DEAD box helicase family
FA584_10040	COG1944	ATP diphosphatase activity
FA584_10060	COG2204	response regulator
FA584_10065	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FA584_10095	COG0411	ABC transporter
FA584_10105	COG1333	cytochrome c biogenesis protein
FA584_10105	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FA584_10145	COG1546	Belongs to the CinA family
FA584_10145	COG1058	Belongs to the CinA family
FA584_10150	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FA584_10160	COG0516	GMP reductase activity
FA584_10160	COG0517	IMP dehydrogenase activity
FA584_10165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FA584_10180	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FA584_10185	COG0436	Aminotransferase
FA584_10200	COG1193	negative regulation of DNA recombination
FA584_10205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FA584_10210	COG0251	oxidation-reduction process
FA584_10215	COG0579	oxidoreductase
FA584_10235	COG3409	Peptidoglycan-binding domain 1 protein
FA584_10235	COG0793	Belongs to the peptidase S41A family
FA584_10250	COG0469	pyruvate kinase activity
FA584_10255	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FA584_10260	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FA584_10265	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FA584_10270	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FA584_10275	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FA584_10285	COG1192	Involved in chromosome partitioning
FA584_10290	COG1475	DNA binding
FA584_10300	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FA584_10305	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FA584_10315	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FA584_10330	COG0811	peptide transport
FA584_10335	COG0848	biopolymer transport protein
FA584_10345	COG0823	Involved in the tonB-independent uptake of proteins
FA584_10360	COG1047	Peptidyl-prolyl cis-trans
FA584_10370	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FA584_10375	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FA584_10380	COG0037	tRNA processing
FA584_10395	COG0493	'glutamate synthase
FA584_10405	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FA584_10410	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FA584_10415	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FA584_10425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FA584_10445	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FA584_10445	COG1776	CheC inhibitor of MCP methylation
FA584_10495	COG0748	coenzyme F420 binding
FA584_10510	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FA584_10515	COG1028	Short-chain dehydrogenase reductase Sdr
FA584_10520	COG1846	Transcriptional regulator
FA584_10535	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FA584_10545	COG1113	amino acid transport
FA584_10550	COG0730	response to heat
FA584_10555	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FA584_10560	COG1301	dicarboxylic acid transport
FA584_10565	COG1301	dicarboxylic acid transport
FA584_10575	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FA584_10575	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FA584_10580	COG1971	Probably functions as a manganese efflux pump
FA584_10600	COG0484	heat shock protein binding
FA584_10610	COG0745	RESPONSE REGULATOR receiver
FA584_10615	COG0642	Histidine kinase
FA584_10620	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FA584_10630	COG0840	transmembrane signaling receptor activity
FA584_10635	COG0318	PFAM AMP-dependent synthetase and ligase
FA584_10640	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FA584_10645	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FA584_10660	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FA584_10665	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FA584_10680	COG3706	GGDEF domain
FA584_10690	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FA584_10710	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FA584_10725	COG2205	protein histidine kinase activity
FA584_10725	COG5002	protein histidine kinase activity
FA584_10725	COG0784	Response regulator, receiver
FA584_10740	COG0322	excinuclease ABC activity
FA584_10750	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FA584_10760	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FA584_10760	COG0519	Catalyzes the synthesis of GMP from XMP
FA584_10790	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FA584_10810	COG0511	ligase activity, forming carbon-carbon bonds
FA584_10815	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FA584_10820	COG0165	Argininosuccinate lyase
FA584_10825	COG0537	adenosine 5'-monophosphoramidase activity
FA584_10830	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FA584_10835	COG0072	phenylalanine-tRNA ligase activity
FA584_10835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FA584_10840	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FA584_10845	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FA584_10850	COG0539	negative regulation of cytoplasmic translation
FA584_10850	COG1185	polyribonucleotide nucleotidyltransferase activity
FA584_10860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FA584_10870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FA584_10880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FA584_10890	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FA584_10895	COG0840	transmembrane signaling receptor activity
FA584_10920	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FA584_10930	COG2996	Protein conserved in bacteria
FA584_10935	COG2081	HI0933 family
FA584_10945	COG1981	membrane
FA584_10960	COG1902	pentaerythritol trinitrate reductase activity
FA584_10965	COG1538	Outer membrane efflux protein
FA584_10990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FA584_10995	COG0840	transmembrane signaling receptor activity
FA584_11000	COG0840	transmembrane signaling receptor activity
FA584_11010	COG0587	DNA-directed DNA polymerase activity
FA584_11015	COG0642	Histidine kinase
FA584_11025	COG1346	cytolysis
FA584_11030	COG1380	Effector of murein hydrolase LrgA
FA584_11050	COG0772	Belongs to the SEDS family
FA584_11055	COG0564	pseudouridine synthase activity
FA584_11065	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FA584_11070	COG1136	(ABC) transporter
FA584_11085	COG0528	UMP kinase activity
FA584_11090	COG1758	RNA polymerase activity
FA584_11095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FA584_11100	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FA584_11105	COG2070	2-Nitropropane dioxygenase
FA584_11110	COG0860	N-Acetylmuramoyl-L-alanine amidase
FA584_11120	COG0563	adenylate kinase activity
FA584_11125	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FA584_11130	COG3706	GGDEF domain
FA584_11140	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FA584_11145	COG0497	DNA recombination
FA584_11155	COG0084	hydrolase, TatD family'
FA584_11160	COG3942	CHAP domain
FA584_11160	COG1388	LysM domain
FA584_11165	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FA584_11170	COG0131	Imidazoleglycerol-phosphate dehydratase
FA584_11175	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FA584_11190	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FA584_11225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FA584_11225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FA584_11235	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FA584_11260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FA584_11265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FA584_11290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FA584_11290	COG1333	cytochrome c biogenesis protein
FA584_11310	COG3545	Serine hydrolase
FA584_11320	COG0463	Glycosyl transferase, family 2
FA584_11335	COG0398	Pfam SNARE associated Golgi protein
FA584_11345	COG0398	Pfam SNARE associated Golgi protein
FA584_11360	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FA584_11370	COG0697	spore germination
FA584_11405	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FA584_11415	COG0243	molybdopterin cofactor binding
FA584_11420	COG0437	4 iron, 4 sulfur cluster binding
FA584_11425	COG0348	domain, Protein
FA584_11430	COG3043	anaerobic respiration
FA584_11435	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
FA584_11435	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FA584_11485	COG1271	oxidase subunit
FA584_11490	COG1294	oxidase, subunit
FA584_11515	COG0243	molybdopterin cofactor binding
FA584_11520	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FA584_11530	COG0745	RESPONSE REGULATOR receiver
FA584_11545	COG2863	cytochrome
FA584_11550	COG0723	plastoquinol--plastocyanin reductase activity
FA584_11555	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FA584_11580	COG0513	Belongs to the DEAD box helicase family
FA584_11590	COG2964	Protein conserved in bacteria
FA584_11595	COG2084	Dehydrogenase
FA584_11615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FA584_11620	COG2226	methyltransferase
FA584_11635	COG3437	response regulator, receiver
FA584_11635	COG0784	Response regulator, receiver
FA584_11650	COG0217	transcriptional regulatory protein
FA584_11660	COG2358	TRAP transporter, solute receptor (TAXI family
FA584_11675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FA584_11700	COG0582	viral genome integration into host DNA
FA584_11730	COG3301	Polysulphide reductase, NrfD
FA584_11735	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FA584_11735	COG1333	cytochrome c biogenesis protein
FA584_11760	COG1136	(ABC) transporter
FA584_11785	COG3279	Response regulator of the LytR AlgR family
FA584_11795	COG1538	Outer membrane efflux protein
FA584_11800	COG2274	protein secretion by the type I secretion system
FA584_11805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FA584_11875	COG2308	Evidence 4 Homologs of previously reported genes of
FA584_11890	COG2966	Psort location CytoplasmicMembrane, score
FA584_11895	COG3610	response to peptide
FA584_11900	COG2217	Heavy metal translocating P-type atpase
FA584_11920	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FA584_11925	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FA584_11925	COG2169	Transcriptional regulator
FA584_11935	COG0352	thiamine-phosphate diphosphorylase activity
FA584_11950	COG1272	protein, Hemolysin III
FA584_11955	COG1280	lysine exporter protein (LysE YggA)
FA584_11960	COG0697	spore germination
FA584_11980	COG2176	DNA-directed DNA polymerase activity
FA584_12000	COG0798	PFAM Bile acid sodium symporter
FA584_12005	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FA584_12015	COG0501	Belongs to the peptidase M48B family
FA584_12035	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FA584_12040	COG2201	protein-glutamate methylesterase activity
FA584_12045	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FA584_12055	COG0133	tryptophan synthase activity
FA584_12060	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FA584_12070	COG0698	ribose 5-phosphate isomerase
FA584_12075	COG1994	Peptidase M50
FA584_12080	COG0681	Belongs to the peptidase S26 family
FA584_12085	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FA584_12095	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FA584_12110	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FA584_12115	COG0612	Peptidase, M16
FA584_12120	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FA584_12150	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FA584_12155	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FA584_12160	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FA584_12165	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FA584_12170	COG0629	single-stranded DNA binding
FA584_12175	COG0360	Binds together with S18 to 16S ribosomal RNA
FA584_12180	COG1466	dna polymerase III delta subunit
FA584_12185	COG0557	exoribonuclease II activity
FA584_12195	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FA584_12200	COG2894	cell division
FA584_12205	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FA584_12210	COG2861	carbohydrate metabolic process
FA584_12220	COG0730	response to heat
FA584_12225	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FA584_12235	COG1760	l-serine dehydratase
FA584_12240	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FA584_12245	COG2860	membrane
FA584_12250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FA584_12265	COG0736	holo-[acyl-carrier-protein] synthase activity
FA584_12270	COG1580	Controls the rotational direction of flagella during chemotaxis
FA584_12275	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FA584_12280	COG0552	protein localization to endoplasmic reticulum
FA584_12285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FA584_12295	COG1418	mRNA catabolic process
FA584_12300	COG1132	(ABC) transporter
FA584_12325	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FA584_12335	COG0745	RESPONSE REGULATOR receiver
FA584_12345	COG5001	Diguanylate cyclase
FA584_12345	COG5002	protein histidine kinase activity
FA584_12350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FA584_12350	COG4191	Histidine kinase
FA584_12365	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FA584_12425	COG1408	metallophosphoesterase
FA584_12460	COG1136	(ABC) transporter
FA584_12480	COG0546	phosphoglycolate phosphatase activity
FA584_12485	COG1454	alcohol dehydrogenase
FA584_12515	COG0242	peptide deformylase activity
FA584_12520	COG0824	Thioesterase
FA584_12535	COG1573	uracil-dna glycosylase
FA584_12550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FA584_12565	COG0745	RESPONSE REGULATOR receiver
FA584_12570	COG3287	FIST C domain
FA584_12570	COG2200	EAL domain
FA584_12570	COG2199	diguanylate cyclase activity
FA584_12585	COG0426	domain, Protein
FA584_12600	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FA584_12605	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FA584_12610	COG1053	succinate dehydrogenase
FA584_12645	COG1196	nuclear chromosome segregation
FA584_12645	COG3264	Mechanosensitive ion channel
FA584_12650	COG1433	Dinitrogenase iron-molybdenum cofactor
FA584_12660	COG0716	FMN binding
FA584_12685	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FA584_12700	COG0346	lactoylglutathione lyase activity
FA584_12735	COG1451	nucleotide metabolic process
FA584_12755	COG2207	Transcriptional regulator
FA584_12775	COG0697	spore germination
FA584_12785	COG3706	GGDEF domain
FA584_12795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FA584_12810	COG3706	GGDEF domain
FA584_12825	COG0840	transmembrane signaling receptor activity
FA584_12845	COG1276	copper resistance
FA584_12850	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
FA584_12860	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FA584_12865	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FA584_12870	COG0784	Response regulator, receiver
FA584_12915	COG0745	RESPONSE REGULATOR receiver
FA584_12920	COG0642	Histidine kinase
FA584_12925	COG3153	acetyltransferase
FA584_12925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FA584_12955	COG0493	'glutamate synthase
FA584_12960	COG0375	protein maturation
FA584_12965	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FA584_12975	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA584_12985	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA584_13020	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FA584_13025	COG0523	cobalamin synthesis protein
FA584_13030	COG2879	small protein
FA584_13035	COG1966	Carbon starvation protein
FA584_13045	COG1053	succinate dehydrogenase
FA584_13080	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FA584_13085	COG0585	pseudouridine synthase activity
FA584_13095	COG0475	glutathione-regulated potassium exporter activity
FA584_13095	COG0569	domain protein
FA584_13110	COG3706	GGDEF domain
FA584_13115	COG0351	phosphomethylpyrimidine kinase
FA584_13135	COG0840	transmembrane signaling receptor activity
FA584_13150	COG0488	(ABC) transporter
FA584_13155	COG1360	Flagellar Motor Protein
FA584_13160	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FA584_13165	COG1309	transcriptional regulator
FA584_13195	COG0778	Nitroreductase
FA584_13200	COG0415	Belongs to the DNA photolyase family
FA584_13210	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FA584_13225	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FA584_13235	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FA584_13280	COG0742	ribosomal rna small subunit methyltransferase
FA584_13290	COG1706	bacterial-type flagellum-dependent cell motility
FA584_13295	COG3951	Flagellar rod assembly protein muramidase FlgJ
FA584_13315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FA584_13325	COG0659	secondary active sulfate transmembrane transporter activity
FA584_13330	COG1942	4-Oxalocrotonate Tautomerase
FA584_13335	COG0356	it plays a direct role in the translocation of protons across the membrane
FA584_13345	COG0352	thiamine-phosphate diphosphorylase activity
FA584_13350	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FA584_13355	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FA584_13360	COG1472	Belongs to the glycosyl hydrolase 3 family
FA584_13365	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FA584_13370	COG0101	tRNA pseudouridine synthase activity
FA584_13380	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FA584_13390	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FA584_13395	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FA584_13400	COG1338	Plays a role in the flagellum-specific transport system
FA584_13405	COG0676	glucose-6-phosphate 1-epimerase activity
FA584_13410	COG2249	NAD(P)H dehydrogenase (quinone) activity
FA584_13425	COG3174	membrane
FA584_13430	COG1032	radical SAM domain protein
FA584_13435	COG0166	Belongs to the GPI family
FA584_13455	COG3259	Nickel-dependent hydrogenase
FA584_13460	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FA584_13465	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FA584_13470	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
FA584_13475	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FA584_13480	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FA584_13485	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FA584_13500	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FA584_13505	COG0298	carbon dioxide binding
FA584_13510	COG0409	Hydrogenase expression formation protein
FA584_13515	COG0309	Hydrogenase expression formation protein (HypE)
FA584_13520	COG0375	protein maturation
FA584_13525	COG1247	-acetyltransferase
FA584_13530	COG0546	phosphoglycolate phosphatase activity
FA584_13550	COG0039	L-malate dehydrogenase activity
FA584_13555	COG0045	succinate-CoA ligase (ADP-forming) activity
FA584_13560	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FA584_13570	COG0674	pyruvate-flavodoxin oxidoreductase activity
FA584_13570	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FA584_13690	COG0842	Transport permease protein
FA584_13690	COG1129	ABC transporter
FA584_13695	COG0842	Transport permease protein
FA584_13700	COG0842	Transport permease protein
FA584_13705	COG2095	MarC family integral membrane protein
FA584_13725	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FA584_13730	COG0750	zinc metalloprotease
FA584_13735	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FA584_13740	COG1028	Short-chain dehydrogenase reductase Sdr
FA584_13745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FA584_13755	COG0167	dihydroorotate dehydrogenase activity
FA584_13760	COG1132	(ABC) transporter
FA584_13765	COG0215	cysteine-tRNA ligase activity
FA584_13770	COG0728	peptidoglycan biosynthetic process
FA584_13780	COG0632	four-way junction helicase activity
FA584_13785	COG1181	Belongs to the D-alanine--D-alanine ligase family
FA584_13800	COG1254	Belongs to the acylphosphatase family
FA584_13805	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FA584_13810	COG0280	phosphate acetyltransferase
FA584_13810	COG0857	belongs to the CobB CobQ family
FA584_13815	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FA584_13820	COG1610	YqeY-like protein
FA584_13840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FA584_13880	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FA584_13885	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FA584_13900	COG0137	argininosuccinate synthase activity
FA584_13905	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FA584_13910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FA584_13915	COG0802	atpase or kinase
FA584_13920	COG1137	ATPase activity
FA584_13925	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FA584_13940	COG0582	viral genome integration into host DNA
FA584_13965	COG0840	transmembrane signaling receptor activity
FA584_13995	COG0784	Response regulator, receiver
FA584_13995	COG3437	response regulator, receiver
FA584_14080	COG0336	Belongs to the RNA methyltransferase TrmD family
FA584_14110	COG1215	transferase activity, transferring glycosyl groups
FA584_14190	COG3093	addiction module antidote protein HigA
FA584_14235	COG1401	restriction endodeoxyribonuclease activity
FA584_14250	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FA584_14255	COG0681	Belongs to the peptidase S26 family
FA584_14260	COG3106	COG3106 Predicted ATPase
FA584_14330	COG1192	Involved in chromosome partitioning
FA584_14335	COG1475	DNA binding