locus-tag	class	description
FA592_00120	COG0745	RESPONSE REGULATOR receiver
FA592_00130	COG0437	4 iron, 4 sulfur cluster binding
FA592_00140	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FA592_00150	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
FA592_00160	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FA592_00170	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FA592_00190	COG1120	ATPase activity
FA592_00205	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FA592_00250	COG1132	(ABC) transporter
FA592_00255	COG1797	cobyrinic acid a,c-diamide synthase activity
FA592_00265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FA592_00265	COG1648	precorrin-2 dehydrogenase activity
FA592_00270	COG1309	transcriptional regulator
FA592_00355	COG0582	viral genome integration into host DNA
FA592_00365	COG0776	regulation of translation
FA592_00375	COG1674	ftsk spoiiie
FA592_00375	COG1196	nuclear chromosome segregation
FA592_00380	COG1049	propionate catabolic process, 2-methylcitrate cycle
FA592_00385	COG1047	Peptidyl-prolyl cis-trans
FA592_00390	COG0574	Belongs to the PEP-utilizing enzyme family
FA592_00390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FA592_00395	COG3713	MltA-interacting MipA family protein
FA592_00405	COG2814	Major facilitator Superfamily
FA592_00425	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FA592_00430	COG0840	transmembrane signaling receptor activity
FA592_00435	COG1832	CoA-binding protein
FA592_00440	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FA592_00450	COG1126	abc transporter atp-binding protein
FA592_00455	COG0765	amino acid transport
FA592_00460	COG4597	amino acid ABC transporter
FA592_00465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FA592_00470	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FA592_00485	COG0586	Pfam SNARE associated Golgi protein
FA592_00490	COG0577	efflux transmembrane transporter activity
FA592_00490	COG1136	(ABC) transporter
FA592_00495	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FA592_00500	COG0492	ferredoxin-NADP+ reductase activity
FA592_00515	COG0727	PFAM Uncharacterised protein family (UPF0153)
FA592_00525	COG0134	indole-3-glycerol-phosphate synthase activity
FA592_00535	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FA592_00540	COG1122	ATPase activity
FA592_00555	COG0310	cobalt ion transport
FA592_00560	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FA592_00565	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FA592_00580	COG0446	pyridine nucleotide-disulphide oxidoreductase
FA592_00595	COG0028	Belongs to the TPP enzyme family
FA592_00600	COG0440	acetolactate synthase activity
FA592_00605	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FA592_00615	COG0493	'glutamate synthase
FA592_00625	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FA592_00655	COG1045	serine acetyltransferase
FA592_00660	COG1166	arginine decarboxylase activity
FA592_00665	COG0124	histidyl-tRNA synthetase
FA592_00680	COG0163	prenyltransferase activity
FA592_00695	COG0840	transmembrane signaling receptor activity
FA592_00700	COG0303	'Molybdopterin
FA592_00705	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FA592_00720	COG1691	(AIR) carboxylase
FA592_00725	COG1606	tRNA processing
FA592_00730	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
FA592_00735	COG3875	lactate racemase activity
FA592_00740	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FA592_00740	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FA592_00755	COG2205	protein histidine kinase activity
FA592_00755	COG0784	Response regulator, receiver
FA592_00760	COG0745	RESPONSE REGULATOR receiver
FA592_00775	COG0588	phosphoglycerate mutase activity
FA592_00785	COG0582	viral genome integration into host DNA
FA592_00790	COG0343	queuine tRNA-ribosyltransferase activity
FA592_00800	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FA592_00810	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FA592_00815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FA592_00835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FA592_00840	COG1187	pseudouridine synthase activity
FA592_00850	COG0028	Belongs to the TPP enzyme family
FA592_00880	COG1309	transcriptional regulator
FA592_00915	COG0840	transmembrane signaling receptor activity
FA592_00915	COG3290	protein histidine kinase activity
FA592_00920	COG1592	Rubrerythrin
FA592_00930	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FA592_00940	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FA592_00940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FA592_00945	COG3030	protein affecting phage T7 exclusion by the F plasmid
FA592_00950	COG0442	prolyl-tRNA aminoacylation
FA592_00955	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FA592_00960	COG0142	geranyltranstransferase activity
FA592_00980	COG1959	2 iron, 2 sulfur cluster binding
FA592_00990	COG3706	GGDEF domain
FA592_00995	COG0525	valine-tRNA ligase activity
FA592_01000	COG0521	Mo-molybdopterin cofactor biosynthetic process
FA592_01005	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FA592_01010	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FA592_01025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FA592_01030	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FA592_01040	COG2195	Cleaves the N-terminal amino acid of tripeptides
FA592_01050	COG0500	methyltransferase
FA592_01065	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FA592_01070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FA592_01075	COG1663	tetraacyldisaccharide 4'-kinase activity
FA592_01080	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FA592_01085	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FA592_01090	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FA592_01105	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FA592_01110	COG0443	Heat shock 70 kDa protein
FA592_01115	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FA592_01120	COG1420	regulation of RNA biosynthetic process
FA592_01130	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FA592_01135	COG1959	2 iron, 2 sulfur cluster binding
FA592_01140	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FA592_01145	COG2404	hydrolase activity, acting on ester bonds
FA592_01155	COG2226	methyltransferase
FA592_01160	COG2203	Gaf domain
FA592_01160	COG2199	diguanylate cyclase activity
FA592_01165	COG0196	riboflavin kinase activity
FA592_01175	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FA592_01180	COG0730	response to heat
FA592_01190	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FA592_01205	COG0527	aspartate kinase activity
FA592_01210	COG0494	nUDIX hydrolase
FA592_01215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FA592_01225	COG0789	Transcriptional regulator
FA592_01230	COG0484	heat shock protein binding
FA592_01240	COG0745	RESPONSE REGULATOR receiver
FA592_01245	COG0642	Histidine kinase
FA592_01260	COG0653	protein targeting
FA592_01265	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FA592_01275	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FA592_01280	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FA592_01290	COG0706	membrane insertase activity
FA592_01295	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FA592_01300	COG0594	ribonuclease P activity
FA592_01305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FA592_01335	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FA592_01350	COG0542	response to heat
FA592_01355	COG0793	Belongs to the peptidase S41A family
FA592_01360	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FA592_01365	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FA592_01370	COG0047	phosphoribosylformylglycinamidine synthase activity
FA592_01380	COG0204	Acyl-transferase
FA592_01385	COG0326	Molecular chaperone. Has ATPase activity
FA592_01405	COG1331	Highly conserved protein containing a thioredoxin domain
FA592_01445	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FA592_01465	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FA592_01475	COG2608	mercury ion transmembrane transporter activity
FA592_01480	COG2217	Heavy metal translocating P-type atpase
FA592_01485	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FA592_01500	COG0275	rRNA processing
FA592_01510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FA592_01515	COG0849	cell division
FA592_01520	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FA592_01530	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FA592_01530	COG2890	protein-(glutamine-N5) methyltransferase activity
FA592_01535	COG0501	Belongs to the peptidase M48B family
FA592_01550	COG0840	transmembrane signaling receptor activity
FA592_01560	COG2151	metal-sulfur cluster biosynthetic enzyme
FA592_01575	COG0138	bifunctional purine biosynthesis protein purh
FA592_01580	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FA592_01590	COG1607	acyl-coa hydrolase
FA592_01595	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FA592_01600	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FA592_01625	COG0842	Transport permease protein
FA592_01630	COG0842	Transport permease protein
FA592_01635	COG1131	(ABC) transporter
FA592_01640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FA592_01645	COG1309	transcriptional regulator
FA592_01655	COG3328	transposase activity
FA592_01660	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FA592_01670	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FA592_01675	COG0805	protein transport
FA592_01680	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FA592_01705	COG3437	response regulator, receiver
FA592_01710	COG2205	protein histidine kinase activity
FA592_01710	COG3437	response regulator, receiver
FA592_01710	COG3850	Histidine kinase
FA592_01710	COG4999	Histidine kinase
FA592_01715	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FA592_01740	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FA592_01745	COG0569	domain protein
FA592_01750	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FA592_01765	COG2068	MobA-Related Protein
FA592_01770	COG3608	succinylglutamate desuccinylase aspartoacylase
FA592_01770	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FA592_01775	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FA592_01790	COG2226	methyltransferase
FA592_01810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FA592_01810	COG2198	Histidine kinase
FA592_01810	COG0784	Response regulator, receiver
FA592_01810	COG2205	protein histidine kinase activity
FA592_01840	COG0646	methionine synthase
FA592_01840	COG1410	methionine synthase
FA592_01855	COG0840	transmembrane signaling receptor activity
FA592_01860	COG1280	lysine exporter protein (LysE YggA)
FA592_01880	COG0004	ammonium transporteR
FA592_01885	COG0347	Belongs to the P(II) protein family
FA592_01905	COG0751	glycine-tRNA ligase activity
FA592_01920	COG0288	reversible hydration of carbon dioxide
FA592_01925	COG3123	guanosine phosphorylase activity
FA592_01935	COG2081	HI0933 family
FA592_01945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FA592_01950	COG0788	formyltetrahydrofolate deformylase activity
FA592_01970	COG0473	3-isopropylmalate dehydrogenase activity
FA592_01975	COG0066	3-isopropylmalate dehydratase activity
FA592_02010	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FA592_02025	COG0708	Exodeoxyribonuclease III
FA592_02040	COG0840	transmembrane signaling receptor activity
FA592_02045	COG2816	NAD+ diphosphatase activity
FA592_02050	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FA592_02055	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FA592_02060	COG4319	ketosteroid isomerase
FA592_02075	COG0840	transmembrane signaling receptor activity
FA592_02080	COG0840	transmembrane signaling receptor activity
FA592_02085	COG4977	sequence-specific DNA binding
FA592_02095	COG0431	NADPH-dependent FMN reductase
FA592_02100	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FA592_02105	COG3706	GGDEF domain
FA592_02115	COG4895	conserved protein (DUF2196)
FA592_02135	COG0513	Belongs to the DEAD box helicase family
FA592_02145	COG0642	Histidine kinase
FA592_02150	COG0745	RESPONSE REGULATOR receiver
FA592_02185	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FA592_02190	COG0372	Belongs to the citrate synthase family
FA592_02195	COG2079	MmgE PrpD family protein
FA592_02205	COG2824	Alkylphosphonate utilization operon protein PhnA
FA592_02215	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FA592_02225	COG4786	Flagellar basal body rod
FA592_02230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FA592_02240	COG1733	regulation of RNA biosynthetic process
FA592_02255	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FA592_02260	COG1121	(ABC) transporter
FA592_02265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FA592_02285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FA592_02290	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FA592_02295	COG3162	membrane
FA592_02300	COG0745	RESPONSE REGULATOR receiver
FA592_02305	COG0642	Histidine kinase
FA592_02320	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FA592_02325	COG1918	ferrous iron import across plasma membrane
FA592_02350	COG3585	molybdate ion transport
FA592_02360	COG0598	Magnesium transport protein CorA
FA592_02365	COG0739	heme binding
FA592_02375	COG0277	FAD linked oxidase domain protein
FA592_02380	COG1295	ribonuclease BN
FA592_02390	COG0305	Participates in initiation and elongation during chromosome replication
FA592_02395	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FA592_02400	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FA592_02430	COG0556	nucleotide-excision repair
FA592_02440	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FA592_02445	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FA592_02450	COG2176	DNA-directed DNA polymerase activity
FA592_02455	COG0135	phosphoribosylanthranilate isomerase activity
FA592_02460	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FA592_02470	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FA592_02485	COG1692	metallophosphoesterase
FA592_02490	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FA592_02500	COG0739	heme binding
FA592_02505	COG0285	dihydrofolate synthase activity
FA592_02510	COG3706	GGDEF domain
FA592_02520	COG0495	leucyl-tRNA aminoacylation
FA592_02525	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FA592_02530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FA592_02535	COG1862	Preprotein translocase
FA592_02540	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FA592_02545	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FA592_02555	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FA592_02565	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FA592_02575	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FA592_02580	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FA592_02585	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FA592_02590	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FA592_02595	COG0210	DNA helicase
FA592_02635	COG0540	Belongs to the ATCase OTCase family
FA592_02645	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FA592_02685	COG0228	four-way junction DNA binding
FA592_02690	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FA592_02695	COG0564	pseudouridine synthase activity
FA592_02700	COG1519	Transferase
FA592_02710	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FA592_02715	COG0752	glycyl-tRNA synthetase alpha subunit
FA592_02725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FA592_02740	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FA592_02745	COG0174	glutamine synthetase
FA592_02755	COG4172	Belongs to the ABC transporter superfamily
FA592_02760	COG0156	8-amino-7-oxononanoate synthase activity
FA592_02765	COG0424	maF-like protein
FA592_02775	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FA592_02800	COG1028	Short-chain dehydrogenase reductase Sdr
FA592_02810	COG0673	inositol 2-dehydrogenase activity
FA592_02815	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FA592_02820	COG0768	penicillin binding
FA592_02830	COG1558	bacterial-type flagellum-dependent cell motility
FA592_02835	COG1815	bacterial-type flagellum-dependent cell motility
FA592_02840	COG0772	Belongs to the SEDS family
FA592_02845	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FA592_02875	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FA592_02885	COG0697	spore germination
FA592_02925	COG0512	Glutamine amidotransferase of anthranilate synthase
FA592_02940	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FA592_02950	COG1518	maintenance of DNA repeat elements
FA592_03080	COG0330	HflC and HflK could
FA592_03115	COG2814	Major facilitator Superfamily
FA592_03125	COG0640	Transcriptional regulator
FA592_03145	COG2301	Belongs to the HpcH HpaI aldolase family
FA592_03150	COG3052	prosthetic group binding
FA592_03165	COG2814	Major facilitator Superfamily
FA592_03175	COG2252	PERMEase
FA592_03180	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FA592_03190	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FA592_03200	COG0133	tryptophan synthase activity
FA592_03210	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FA592_03215	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FA592_03220	COG3706	GGDEF domain
FA592_03240	COG2199	diguanylate cyclase activity
FA592_03240	COG2200	EAL domain
FA592_03240	COG2202	Pas domain
FA592_03250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FA592_03270	COG0488	(ABC) transporter
FA592_03275	COG2207	Transcriptional regulator
FA592_03275	COG4753	response regulator
FA592_03290	COG1151	hydroxylamine reductase activity
FA592_03300	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FA592_03310	COG0650	Formate hydrogenlyase subunit 4
FA592_03315	COG4237	Hydrogenase 4 membrane
FA592_03320	COG0651	ATP synthesis coupled electron transport
FA592_03325	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FA592_03325	COG3261	NADH dehydrogenase
FA592_03335	COG3260	NADH ubiquinone oxidoreductase 20
FA592_03370	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FA592_03385	COG2171	N-acyltransferase activity
FA592_03390	COG0489	protein tyrosine kinase activity
FA592_03395	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FA592_03395	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FA592_03405	COG2046	Belongs to the sulfate adenylyltransferase family
FA592_03415	COG2353	YceI-like domain
FA592_03420	COG1739	Uncharacterized protein family UPF0029
FA592_03425	COG0157	Belongs to the NadC ModD family
FA592_03440	COG3842	ATPase activity
FA592_03465	COG1686	Belongs to the peptidase S11 family
FA592_03470	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FA592_03475	COG1136	(ABC) transporter
FA592_03475	COG0577	efflux transmembrane transporter activity
FA592_03480	COG1136	(ABC) transporter
FA592_03505	COG0668	transmembrane transport
FA592_03510	COG5001	Diguanylate cyclase
FA592_03510	COG3300	MHYT domain
FA592_03525	COG3645	SOS response
FA592_03635	COG0284	orotidine-5'-phosphate decarboxylase activity
FA592_03640	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FA592_03645	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FA592_03655	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FA592_03660	COG0697	spore germination
FA592_03665	COG0668	transmembrane transport
FA592_03670	COG1160	GTP binding
FA592_03685	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FA592_03695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FA592_03700	COG1183	phosphatidylcholine synthase activity
FA592_03710	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FA592_03715	COG2264	protein methyltransferase activity
FA592_03720	COG0745	RESPONSE REGULATOR receiver
FA592_03725	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FA592_03730	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FA592_03745	COG1086	Polysaccharide biosynthesis protein
FA592_03750	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FA592_03765	COG1442	glycosyl transferase family 8
FA592_03765	COG1216	Glycosyl transferase, family 2
FA592_03775	COG0110	maltose O-acetyltransferase activity
FA592_03800	COG0028	Belongs to the TPP enzyme family
FA592_03810	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FA592_03825	COG1793	dna ligase
FA592_03835	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FA592_03840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FA592_03865	COG0859	PFAM glycosyl transferase family 9
FA592_03885	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FA592_03890	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FA592_03890	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FA592_03895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FA592_03925	COG5001	Diguanylate cyclase
FA592_03925	COG5002	protein histidine kinase activity
FA592_03930	COG0697	spore germination
FA592_03940	COG3706	GGDEF domain
FA592_03965	COG0840	transmembrane signaling receptor activity
FA592_03970	COG1984	allophanate hydrolase subunit 2
FA592_03980	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FA592_03985	COG0445	tRNA wobble uridine modification
FA592_03990	COG0723	plastoquinol--plastocyanin reductase activity
FA592_03995	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FA592_04000	COG2857	Cytochrome c1
FA592_04010	COG0825	malonyl-CoA metabolic process
FA592_04015	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FA592_04020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FA592_04030	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FA592_04035	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FA592_04040	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FA592_04065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FA592_04070	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FA592_04085	COG0463	Glycosyl transferase, family 2
FA592_04100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FA592_04105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FA592_04130	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FA592_04165	COG0662	Cupin 2, conserved barrel domain protein
FA592_04165	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FA592_04170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FA592_04195	COG0745	RESPONSE REGULATOR receiver
FA592_04210	COG0398	Pfam SNARE associated Golgi protein
FA592_04215	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FA592_04230	COG0390	transport system, permease component
FA592_04235	COG0439	Biotin carboxylase
FA592_04250	COG0513	Belongs to the DEAD box helicase family
FA592_04255	COG1671	Belongs to the UPF0178 family
FA592_04260	COG0667	Aldo Keto reductase
FA592_04265	COG2814	Major facilitator Superfamily
FA592_04270	COG2207	Transcriptional regulator
FA592_04290	COG0573	inorganic phosphate transmembrane transporter activity
FA592_04300	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FA592_04310	COG3384	dioxygenase
FA592_04330	COG0745	RESPONSE REGULATOR receiver
FA592_04340	COG1607	acyl-coa hydrolase
FA592_04360	COG1733	regulation of RNA biosynthetic process
FA592_04365	COG2249	NAD(P)H dehydrogenase (quinone) activity
FA592_04370	COG3852	Histidine kinase
FA592_04375	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FA592_04380	COG0602	queuosine metabolic process
FA592_04410	COG1702	phosphate starvation-inducible protein PhoH
FA592_04420	COG2814	Major facilitator Superfamily
FA592_04425	COG0477	Major facilitator Superfamily
FA592_04435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FA592_04455	COG3787	Belongs to the UPF0306 family
FA592_04460	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FA592_04490	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FA592_04490	COG1013	pyruvate-flavodoxin oxidoreductase activity
FA592_04490	COG0674	pyruvate-flavodoxin oxidoreductase activity
FA592_04490	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FA592_04500	COG0471	metal ion transport
FA592_04515	COG2885	chlorophyll binding
FA592_04515	COG3047	cAMP biosynthetic process
FA592_04530	COG2207	Transcriptional regulator
FA592_04535	COG0519	Catalyzes the synthesis of GMP from XMP
FA592_04555	COG1979	alcohol dehydrogenase
FA592_04570	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FA592_04585	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FA592_04590	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FA592_04595	COG1074	ATP-dependent DNA helicase activity
FA592_04635	COG3278	Belongs to the heme-copper respiratory oxidase family
FA592_04640	COG0745	RESPONSE REGULATOR receiver
FA592_04655	COG0505	Belongs to the CarA family
FA592_04675	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FA592_04680	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FA592_04685	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FA592_04700	COG0546	phosphoglycolate phosphatase activity
FA592_04715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FA592_04720	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FA592_04725	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FA592_04730	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FA592_04745	COG0203	ribosomal protein L17
FA592_04755	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FA592_04760	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FA592_04765	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FA592_04770	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FA592_04780	COG0024	Methionine aminopeptidase
FA592_04785	COG0201	protein transport
FA592_04790	COG0200	Binds to the 23S rRNA
FA592_04795	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FA592_04800	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FA592_04805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FA592_04810	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FA592_04815	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FA592_04825	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FA592_04830	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FA592_04835	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FA592_04840	COG0255	Belongs to the universal ribosomal protein uL29 family
FA592_04845	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FA592_04850	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FA592_04860	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FA592_04865	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FA592_04870	COG0089	rRNA binding
FA592_04875	COG0088	Forms part of the polypeptide exit tunnel
FA592_04880	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FA592_04885	COG0051	transcription antitermination factor activity, RNA binding
FA592_04900	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FA592_04905	COG0672	)-iron permease
FA592_04930	COG0577	efflux transmembrane transporter activity
FA592_04930	COG1136	(ABC) transporter
FA592_04950	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FA592_04955	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FA592_04960	COG0571	ribonuclease III activity
FA592_04965	COG0328	RNA-DNA hybrid ribonuclease activity
FA592_04975	COG0358	DNA primase activity
FA592_04980	COG0137	argininosuccinate synthase activity
FA592_04985	COG2201	protein-glutamate methylesterase activity
FA592_05005	COG2205	protein histidine kinase activity
FA592_05010	COG2201	protein-glutamate methylesterase activity
FA592_05015	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FA592_05045	COG2198	Histidine kinase
FA592_05045	COG0643	Histidine kinase
FA592_05055	COG0840	transmembrane signaling receptor activity
FA592_05060	COG0835	chemotaxis
FA592_05065	COG0745	RESPONSE REGULATOR receiver
FA592_05070	COG0484	heat shock protein binding
FA592_05095	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FA592_05100	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FA592_05120	COG1280	lysine exporter protein (LysE YggA)
FA592_05125	COG1090	epimerase
FA592_05170	COG2962	Rard protein
FA592_05180	COG3850	Histidine kinase
FA592_05180	COG5002	protein histidine kinase activity
FA592_05185	COG2194	sulfuric ester hydrolase activity
FA592_05195	COG2200	EAL domain
FA592_05210	COG1968	undecaprenyl-diphosphatase activity
FA592_05215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FA592_05220	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
FA592_05245	COG1027	Aspartate ammonia-lyase
FA592_05260	COG0252	asparaginase activity
FA592_05265	COG4191	Histidine kinase
FA592_05270	COG0745	RESPONSE REGULATOR receiver
FA592_05275	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FA592_05285	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FA592_05290	COG0804	urea catabolic process
FA592_05295	COG0832	Belongs to the urease beta subunit family
FA592_05295	COG0831	urea catabolic process
FA592_05300	COG0829	nickel cation binding
FA592_05330	COG2205	protein histidine kinase activity
FA592_05330	COG0784	Response regulator, receiver
FA592_05335	COG0745	RESPONSE REGULATOR receiver
FA592_05350	COG0714	Associated with various cellular activities
FA592_05395	COG0765	amino acid transport
FA592_05430	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FA592_05435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FA592_05470	COG0709	Synthesizes selenophosphate from selenide and ATP
FA592_05475	COG0425	Belongs to the sulfur carrier protein TusA family
FA592_05485	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FA592_05490	COG5002	protein histidine kinase activity
FA592_05490	COG3447	MASE1 domain protein
FA592_05490	COG5001	Diguanylate cyclase
FA592_05500	COG2814	Major facilitator Superfamily
FA592_05525	COG3839	Belongs to the ABC transporter superfamily
FA592_05530	COG4662	Binding-protein-dependent transport system inner membrane component
FA592_05535	COG2998	abc-type tungstate transport system, permease component
FA592_05545	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FA592_05555	COG0437	4 iron, 4 sulfur cluster binding
FA592_05580	COG1120	ATPase activity
FA592_05595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FA592_05610	COG0848	biopolymer transport protein
FA592_05615	COG0811	peptide transport
FA592_05640	COG0500	methyltransferase
FA592_05650	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FA592_05655	COG4208	sulfate ABC transporter
FA592_05660	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FA592_05665	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FA592_05670	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FA592_05710	COG0437	4 iron, 4 sulfur cluster binding
FA592_05740	COG2205	protein histidine kinase activity
FA592_05750	COG1921	L-seryl-tRNASec selenium transferase activity
FA592_05775	COG1741	Belongs to the pirin family
FA592_05810	COG0745	RESPONSE REGULATOR receiver
FA592_05815	COG0642	Histidine kinase
FA592_05825	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FA592_05830	COG0463	Glycosyl transferase, family 2
FA592_05840	COG1028	Short-chain dehydrogenase reductase Sdr
FA592_05895	COG0513	Belongs to the DEAD box helicase family
FA592_05925	COG1305	Transglutaminase-like
FA592_05940	COG0745	RESPONSE REGULATOR receiver
FA592_05960	COG0439	Biotin carboxylase
FA592_05975	COG1116	anion transmembrane transporter activity
FA592_05980	COG2011	ABC-type metal ion transport system permease component
FA592_05990	COG0642	Histidine kinase
FA592_05995	COG0745	RESPONSE REGULATOR receiver
FA592_06030	COG0300	oxidoreductase activity
FA592_06045	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FA592_06055	COG2814	Major facilitator Superfamily
FA592_06060	COG1238	metal cluster binding
FA592_06075	COG0471	metal ion transport
FA592_06090	COG0303	'Molybdopterin
FA592_06095	COG0314	molybdopterin synthase activity
FA592_06115	COG1157	protein secretion by the type III secretion system
FA592_06120	COG0302	gtp cyclohydrolase
FA592_06125	COG0544	peptidyl-prolyl cis-trans isomerase activity
FA592_06130	COG0740	serine-type endopeptidase activity
FA592_06145	COG0606	chelatase, subunit chli
FA592_06150	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FA592_06150	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FA592_06160	COG2022	thiamine diphosphate biosynthetic process
FA592_06190	COG0582	viral genome integration into host DNA
FA592_06275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FA592_06280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FA592_06295	COG0463	Glycosyl transferase, family 2
FA592_06310	COG0671	phosphoesterase, PA-phosphatase related
FA592_06325	COG1012	belongs to the aldehyde dehydrogenase family
FA592_06340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FA592_06365	COG0840	transmembrane signaling receptor activity
FA592_06370	COG2183	response to ionizing radiation
FA592_06390	COG0842	Transport permease protein
FA592_06395	COG0842	Transport permease protein
FA592_06400	COG1131	(ABC) transporter
FA592_06405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FA592_06415	COG0778	Nitroreductase
FA592_06460	COG0577	efflux transmembrane transporter activity
FA592_06465	COG1136	(ABC) transporter
FA592_06475	COG1472	Belongs to the glycosyl hydrolase 3 family
FA592_06505	COG0431	NADPH-dependent FMN reductase
FA592_06515	COG0300	oxidoreductase activity
FA592_06525	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FA592_06530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FA592_06570	COG0745	RESPONSE REGULATOR receiver
FA592_06575	COG0642	Histidine kinase
FA592_06585	COG0175	sulfate reduction
FA592_06590	COG0175	sulfate reduction
FA592_06595	COG2895	sulfate adenylyltransferase (ATP) activity
FA592_06605	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FA592_06615	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FA592_06620	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FA592_06620	COG1648	precorrin-2 dehydrogenase activity
FA592_06625	COG0626	cystathionine gamma-synthase activity
FA592_06635	COG0482	sulfurtransferase activity
FA592_06655	COG3706	GGDEF domain
FA592_06665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FA592_06675	COG0861	Integral membrane protein TerC family
FA592_06680	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FA592_06685	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FA592_06690	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FA592_06695	COG0280	phosphate acetyltransferase
FA592_06695	COG0281	malic enzyme
FA592_06700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FA592_06710	COG0439	Biotin carboxylase
FA592_06715	COG0511	ligase activity, forming carbon-carbon bonds
FA592_06720	COG0717	Belongs to the dCTP deaminase family
FA592_06740	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FA592_06745	COG1073	alpha beta
FA592_06760	COG1086	Polysaccharide biosynthesis protein
FA592_06765	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FA592_06770	COG1083	cytidylyl-transferase
FA592_06780	COG2226	methyltransferase
FA592_06785	COG2089	acid synthase
FA592_06790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FA592_06820	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FA592_06825	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FA592_06830	COG0372	Belongs to the citrate synthase family
FA592_06845	COG0148	phosphopyruvate hydratase activity
FA592_06850	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FA592_06855	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FA592_06865	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FA592_06875	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FA592_06905	COG1408	metallophosphoesterase
FA592_06910	COG1115	amino acid carrier protein
FA592_06915	COG2233	PERMEase
FA592_06920	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FA592_06925	COG0575	Belongs to the CDS family
FA592_06960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FA592_06970	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FA592_06975	COG0746	molybdenum cofactor guanylyltransferase activity
FA592_07010	COG0315	cyclic pyranopterin monophosphate synthase activity
FA592_07015	COG2921	Belongs to the UPF0250 family
FA592_07075	COG0670	Belongs to the BI1 family
FA592_07090	COG0437	4 iron, 4 sulfur cluster binding
FA592_07095	COG0243	molybdopterin cofactor binding
FA592_07100	COG4106	trans-aconitate 2-methyltransferase activity
FA592_07120	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FA592_07125	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FA592_07135	COG0233	cytoplasmic translational termination
FA592_07140	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FA592_07165	COG1704	LemA family
FA592_07180	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FA592_07185	COG1749	Flagellar hook protein flgE
FA592_07190	COG1749	Flagellar hook protein flgE
FA592_07195	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FA592_07200	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FA592_07210	COG0592	DNA-directed DNA polymerase activity
FA592_07240	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FA592_07245	COG1194	a g-specific adenine glycosylase
FA592_07250	COG2814	Major facilitator Superfamily
FA592_07265	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FA592_07325	COG1335	isochorismatase
FA592_07345	COG2207	Transcriptional regulator
FA592_07345	COG3708	Transcriptional regulator
FA592_07355	COG1355	regulation of microtubule-based process
FA592_07365	COG2078	PFAM AMMECR1 domain protein
FA592_07400	COG3150	esterase
FA592_07410	COG3383	formate dehydrogenase (NAD+) activity
FA592_07440	COG0129	dihydroxy-acid dehydratase activity
FA592_07445	COG2095	MarC family integral membrane protein
FA592_07470	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FA592_07475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FA592_07480	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FA592_07495	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FA592_07495	COG1328	CTP reductase activity
FA592_07500	COG1794	racemase activity, acting on amino acids and derivatives
FA592_07505	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FA592_07510	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FA592_07515	COG0564	pseudouridine synthase activity
FA592_07520	COG0179	Fumarylacetoacetate (FAA) hydrolase
FA592_07525	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FA592_07535	COG0107	imidazoleglycerol-phosphate synthase activity
FA592_07545	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FA592_07550	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FA592_07550	COG0517	IMP dehydrogenase activity
FA592_07555	COG1187	pseudouridine synthase activity
FA592_07580	COG2257	FlhB HrpN YscU SpaS Family
FA592_07600	COG0237	dephospho-CoA kinase activity
FA592_07605	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FA592_07615	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FA592_07620	COG0268	Binds directly to 16S ribosomal RNA
FA592_07625	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FA592_07630	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FA592_07640	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FA592_07645	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FA592_07650	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FA592_07655	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FA592_07660	COG0348	domain, Protein
FA592_07670	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FA592_07685	COG0754	glutathionylspermidine amidase activity
FA592_07690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FA592_07705	COG2194	sulfuric ester hydrolase activity
FA592_07750	COG0642	Histidine kinase
FA592_07755	COG0745	RESPONSE REGULATOR receiver
FA592_07775	COG1127	ABC transporter
FA592_07780	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FA592_07795	COG2095	MarC family integral membrane protein
FA592_07800	COG0840	transmembrane signaling receptor activity
FA592_07810	COG0784	Response regulator, receiver
FA592_07810	COG3437	response regulator, receiver
FA592_07820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FA592_07830	COG5002	protein histidine kinase activity
FA592_07840	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FA592_07850	COG0004	ammonium transporteR
FA592_07855	COG0667	Aldo Keto reductase
FA592_07865	COG0745	RESPONSE REGULATOR receiver
FA592_07880	COG0765	amino acid transport
FA592_07920	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FA592_07930	COG0318	PFAM AMP-dependent synthetase and ligase
FA592_07935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FA592_07940	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_07945	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_07950	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_07955	COG0649	NAD binding
FA592_07975	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FA592_07980	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_07985	COG0839	Belongs to the complex I subunit 6 family
FA592_07990	COG0713	ATP synthesis coupled electron transport
FA592_07995	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FA592_08015	COG1012	belongs to the aldehyde dehydrogenase family
FA592_08025	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FA592_08040	COG0840	transmembrane signaling receptor activity
FA592_08045	COG0840	transmembrane signaling receptor activity
FA592_08065	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FA592_08070	COG0254	rRNA binding
FA592_08075	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FA592_08080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FA592_08095	COG0436	Aminotransferase
FA592_08100	COG0460	homoserine dehydrogenase
FA592_08105	COG0792	nuclease activity
FA592_08110	COG3118	belongs to the thioredoxin family
FA592_08115	COG0492	ferredoxin-NADP+ reductase activity
FA592_08120	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FA592_08125	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FA592_08130	COG1242	4 iron, 4 sulfur cluster binding
FA592_08145	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FA592_08145	COG0140	phosphoribosyl-ATP diphosphatase activity
FA592_08160	COG1012	belongs to the aldehyde dehydrogenase family
FA592_08165	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FA592_08180	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FA592_08185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FA592_08190	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FA592_08195	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FA592_08210	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FA592_08230	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FA592_08235	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FA592_08240	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FA592_08245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FA592_08250	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FA592_08260	COG0835	chemotaxis
FA592_08260	COG0784	Response regulator, receiver
FA592_08265	COG2198	Histidine kinase
FA592_08265	COG0643	Histidine kinase
FA592_08265	COG0784	Response regulator, receiver
FA592_08270	COG0835	chemotaxis
FA592_08285	COG0560	Phosphoserine phosphatase
FA592_08305	COG0193	aminoacyl-tRNA hydrolase activity
FA592_08315	COG0019	diaminopimelate decarboxylase activity
FA592_08320	COG1605	Chorismate mutase
FA592_08320	COG0077	Prephenate dehydratase
FA592_08325	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FA592_08335	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FA592_08345	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FA592_08350	COG0735	belongs to the Fur family
FA592_08355	COG0450	alkyl hydroperoxide reductase
FA592_08360	COG0840	transmembrane signaling receptor activity
FA592_08370	COG0105	UTP biosynthetic process
FA592_08380	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FA592_08385	COG0416	fatty acid biosynthetic process
FA592_08390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FA592_08395	COG0714	Associated with various cellular activities
FA592_08415	COG2304	oxidoreductase activity
FA592_08430	COG0287	Prephenate dehydrogenase
FA592_08435	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FA592_08445	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FA592_08455	COG0745	RESPONSE REGULATOR receiver
FA592_08465	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FA592_08475	COG0157	Belongs to the NadC ModD family
FA592_08480	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FA592_08495	COG0850	regulation of cytokinetic process
FA592_08500	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FA592_08520	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FA592_08530	COG0779	Required for maturation of 30S ribosomal subunits
FA592_08535	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FA592_08535	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FA592_08550	COG5001	Diguanylate cyclase
FA592_08560	COG5002	protein histidine kinase activity
FA592_08590	COG3258	Cytochrome c
FA592_08600	COG1242	4 iron, 4 sulfur cluster binding
FA592_08605	COG0243	molybdopterin cofactor binding
FA592_08610	COG0437	4 iron, 4 sulfur cluster binding
FA592_08615	COG3301	Polysulphide reductase, NrfD
FA592_08620	COG2199	diguanylate cyclase activity
FA592_08620	COG3287	FIST C domain
FA592_08620	COG2200	EAL domain
FA592_08630	COG0437	4 iron, 4 sulfur cluster binding
FA592_08635	COG3301	Polysulphide reductase, NrfD
FA592_08640	COG0745	RESPONSE REGULATOR receiver
FA592_08655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FA592_08680	COG0848	biopolymer transport protein
FA592_08685	COG0811	peptide transport
FA592_08690	COG1227	inorganic diphosphatase activity
FA592_08710	COG1570	exodeoxyribonuclease VII activity
FA592_08725	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FA592_08745	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FA592_08755	COG2207	Transcriptional regulator
FA592_08760	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FA592_08765	COG0583	DNA-binding transcription factor activity
FA592_08770	COG2855	membrane
FA592_08775	COG0386	Belongs to the glutathione peroxidase family
FA592_08780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FA592_08790	COG0402	S-adenosylhomocysteine deaminase activity
FA592_08795	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FA592_08800	COG0006	proline dipeptidase activity
FA592_08805	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FA592_08810	COG1419	protein localization to endoplasmic reticulum
FA592_08815	COG0455	bacterial-type flagellum organization
FA592_08825	COG1191	sigma factor activity
FA592_08830	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FA592_08835	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FA592_08835	COG1776	CheC inhibitor of MCP methylation
FA592_08850	COG0463	Glycosyl transferase, family 2
FA592_08860	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FA592_08880	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FA592_08890	COG1040	competence protein
FA592_08925	COG2204	response regulator
FA592_08930	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FA592_08940	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FA592_08945	COG0731	radical SAM domain protein
FA592_08955	COG2358	TRAP transporter, solute receptor (TAXI family
FA592_08965	COG0582	viral genome integration into host DNA
FA592_09020	COG1464	Belongs to the NlpA lipoprotein family
FA592_09025	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FA592_09030	COG2011	ABC-type metal ion transport system permease component
FA592_09035	COG0306	phosphate transporter
FA592_09040	COG0039	L-malate dehydrogenase activity
FA592_09045	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FA592_09090	COG2200	EAL domain
FA592_09090	COG3287	FIST C domain
FA592_09090	COG2199	diguanylate cyclase activity
FA592_09110	COG3118	belongs to the thioredoxin family
FA592_09120	COG4336	lyase activity
FA592_09145	COG4628	conserved protein (DUF2132)
FA592_09150	COG4221	oxidoreductase activity
FA592_09185	COG3022	response to hydroperoxide
FA592_09210	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FA592_09215	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FA592_09230	COG0250	Participates in transcription elongation, termination and antitermination
FA592_09235	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FA592_09240	COG0081	regulation of translation
FA592_09245	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FA592_09250	COG0222	ribosome binding
FA592_09255	COG0085	RNA polymerase activity
FA592_09260	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FA592_09265	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FA592_09275	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FA592_09285	COG0697	spore germination
FA592_09290	COG0656	L-ascorbic acid biosynthetic process
FA592_09300	COG0471	metal ion transport
FA592_09305	COG0534	Mate efflux family protein
FA592_09320	COG0745	RESPONSE REGULATOR receiver
FA592_09325	COG0747	negative chemotaxis
FA592_09335	COG0840	transmembrane signaling receptor activity
FA592_09340	COG0840	transmembrane signaling receptor activity
FA592_09350	COG1034	ATP synthesis coupled electron transport
FA592_09355	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FA592_09360	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_09365	COG0839	Belongs to the complex I subunit 6 family
FA592_09370	COG0713	ATP synthesis coupled electron transport
FA592_09375	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FA592_09380	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_09385	COG1007	ATP synthesis coupled electron transport
FA592_09410	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FA592_09415	COG0649	NAD binding
FA592_09415	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_09420	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_09425	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_09440	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FA592_09460	COG0357	Ribosomal RNA small subunit methyltransferase G
FA592_09475	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FA592_09480	COG1970	mechanosensitive ion channel activity
FA592_09490	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FA592_09495	COG0113	porphobilinogen synthase activity
FA592_09500	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FA592_09510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FA592_09515	COG0247	lactate metabolic process
FA592_09530	COG3012	SEC-C Motif Domain Protein
FA592_09545	COG3706	GGDEF domain
FA592_09550	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FA592_09560	COG1053	succinate dehydrogenase
FA592_09565	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FA592_09575	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FA592_09580	COG0628	permease
FA592_09585	COG2255	four-way junction helicase activity
FA592_09590	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FA592_09600	COG0159	tryptophan synthase activity
FA592_09620	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FA592_09625	COG1136	(ABC) transporter
FA592_09630	COG1684	flagellar biosynthetic protein fliR
FA592_09640	COG0194	GDP metabolic process
FA592_09645	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FA592_09650	COG0018	arginyl-trna synthetase
FA592_09660	COG2199	diguanylate cyclase activity
FA592_09660	COG2200	EAL domain
FA592_09660	COG3287	FIST C domain
FA592_09710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FA592_09720	COG0149	triose-phosphate isomerase activity
FA592_09725	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FA592_09735	COG0195	Participates in both transcription termination and antitermination
FA592_09770	COG0037	tRNA processing
FA592_09775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FA592_09780	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FA592_09785	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FA592_09810	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FA592_09815	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FA592_09820	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FA592_09850	COG2326	polyphosphate kinase activity
FA592_09865	COG0723	plastoquinol--plastocyanin reductase activity
FA592_09870	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FA592_09885	COG0513	Belongs to the DEAD box helicase family
FA592_09890	COG1944	ATP diphosphatase activity
FA592_09910	COG2204	response regulator
FA592_09915	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FA592_09945	COG0411	ABC transporter
FA592_09955	COG1333	cytochrome c biogenesis protein
FA592_09955	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FA592_09995	COG1546	Belongs to the CinA family
FA592_09995	COG1058	Belongs to the CinA family
FA592_10000	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FA592_10010	COG0517	IMP dehydrogenase activity
FA592_10010	COG0516	GMP reductase activity
FA592_10015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FA592_10030	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FA592_10035	COG0436	Aminotransferase
FA592_10050	COG1193	negative regulation of DNA recombination
FA592_10055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FA592_10060	COG0251	oxidation-reduction process
FA592_10065	COG0579	oxidoreductase
FA592_10085	COG3409	Peptidoglycan-binding domain 1 protein
FA592_10085	COG0793	Belongs to the peptidase S41A family
FA592_10100	COG0469	pyruvate kinase activity
FA592_10105	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FA592_10110	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FA592_10115	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FA592_10120	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FA592_10125	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FA592_10135	COG1192	Involved in chromosome partitioning
FA592_10140	COG1475	DNA binding
FA592_10150	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FA592_10155	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FA592_10165	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FA592_10180	COG0811	peptide transport
FA592_10185	COG0848	biopolymer transport protein
FA592_10195	COG0823	Involved in the tonB-independent uptake of proteins
FA592_10210	COG1047	Peptidyl-prolyl cis-trans
FA592_10220	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FA592_10225	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FA592_10230	COG0037	tRNA processing
FA592_10240	COG0067	glutamate synthase
FA592_10240	COG0069	glutamate synthase activity
FA592_10240	COG0070	glutamate synthase
FA592_10245	COG0493	'glutamate synthase
FA592_10255	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FA592_10260	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FA592_10265	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FA592_10275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FA592_10295	COG1776	CheC inhibitor of MCP methylation
FA592_10295	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FA592_10345	COG0748	coenzyme F420 binding
FA592_10360	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FA592_10365	COG1028	Short-chain dehydrogenase reductase Sdr
FA592_10370	COG1846	Transcriptional regulator
FA592_10385	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FA592_10395	COG1113	amino acid transport
FA592_10400	COG0730	response to heat
FA592_10405	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FA592_10410	COG1301	dicarboxylic acid transport
FA592_10415	COG1301	dicarboxylic acid transport
FA592_10425	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FA592_10425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FA592_10430	COG1971	Probably functions as a manganese efflux pump
FA592_10450	COG0484	heat shock protein binding
FA592_10460	COG0745	RESPONSE REGULATOR receiver
FA592_10465	COG0642	Histidine kinase
FA592_10470	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FA592_10480	COG0840	transmembrane signaling receptor activity
FA592_10485	COG0318	PFAM AMP-dependent synthetase and ligase
FA592_10490	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FA592_10495	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FA592_10510	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FA592_10515	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FA592_10530	COG3706	GGDEF domain
FA592_10540	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FA592_10560	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FA592_10575	COG2205	protein histidine kinase activity
FA592_10575	COG0784	Response regulator, receiver
FA592_10575	COG5002	protein histidine kinase activity
FA592_10590	COG0322	excinuclease ABC activity
FA592_10600	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FA592_10610	COG0519	Catalyzes the synthesis of GMP from XMP
FA592_10610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FA592_10630	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FA592_10640	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FA592_10660	COG0511	ligase activity, forming carbon-carbon bonds
FA592_10665	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FA592_10670	COG0165	Argininosuccinate lyase
FA592_10675	COG0537	adenosine 5'-monophosphoramidase activity
FA592_10680	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FA592_10685	COG0072	phenylalanine-tRNA ligase activity
FA592_10685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FA592_10690	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FA592_10695	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FA592_10700	COG1185	polyribonucleotide nucleotidyltransferase activity
FA592_10700	COG0539	negative regulation of cytoplasmic translation
FA592_10710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FA592_10720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FA592_10730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FA592_10740	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FA592_10765	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FA592_10775	COG2996	Protein conserved in bacteria
FA592_10780	COG2081	HI0933 family
FA592_10805	COG1902	pentaerythritol trinitrate reductase activity
FA592_10810	COG1538	Outer membrane efflux protein
FA592_10835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FA592_10840	COG0840	transmembrane signaling receptor activity
FA592_10845	COG0840	transmembrane signaling receptor activity
FA592_10855	COG0587	DNA-directed DNA polymerase activity
FA592_10860	COG0642	Histidine kinase
FA592_10870	COG1346	cytolysis
FA592_10875	COG1380	Effector of murein hydrolase LrgA
FA592_10895	COG0772	Belongs to the SEDS family
FA592_10900	COG0564	pseudouridine synthase activity
FA592_10910	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FA592_10915	COG1136	(ABC) transporter
FA592_10930	COG0528	UMP kinase activity
FA592_10935	COG1758	RNA polymerase activity
FA592_10940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FA592_10945	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FA592_10950	COG2070	2-Nitropropane dioxygenase
FA592_10955	COG0860	N-Acetylmuramoyl-L-alanine amidase
FA592_10965	COG0563	adenylate kinase activity
FA592_10970	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FA592_10975	COG3706	GGDEF domain
FA592_10985	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FA592_10990	COG0497	DNA recombination
FA592_11000	COG0084	hydrolase, TatD family'
FA592_11005	COG1388	LysM domain
FA592_11005	COG3942	CHAP domain
FA592_11010	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FA592_11015	COG0131	Imidazoleglycerol-phosphate dehydratase
FA592_11020	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FA592_11035	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FA592_11070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FA592_11070	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FA592_11080	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FA592_11105	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FA592_11110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FA592_11150	COG3005	denitrification pathway
FA592_11160	COG1333	cytochrome c biogenesis protein
FA592_11160	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FA592_11180	COG3545	Serine hydrolase
FA592_11190	COG0463	Glycosyl transferase, family 2
FA592_11205	COG0398	Pfam SNARE associated Golgi protein
FA592_11215	COG0398	Pfam SNARE associated Golgi protein
FA592_11225	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FA592_11235	COG0697	spore germination
FA592_11270	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FA592_11280	COG0243	molybdopterin cofactor binding
FA592_11285	COG0437	4 iron, 4 sulfur cluster binding
FA592_11290	COG0348	domain, Protein
FA592_11295	COG3043	anaerobic respiration
FA592_11300	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FA592_11300	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
FA592_11350	COG1271	oxidase subunit
FA592_11355	COG1294	oxidase, subunit
FA592_11380	COG0243	molybdopterin cofactor binding
FA592_11385	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FA592_11395	COG0745	RESPONSE REGULATOR receiver
FA592_11410	COG2863	cytochrome
FA592_11415	COG0723	plastoquinol--plastocyanin reductase activity
FA592_11420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FA592_11435	COG3287	FIST C domain
FA592_11435	COG2200	EAL domain
FA592_11435	COG2199	diguanylate cyclase activity
FA592_11445	COG0513	Belongs to the DEAD box helicase family
FA592_11455	COG2964	Protein conserved in bacteria
FA592_11460	COG2084	Dehydrogenase
FA592_11480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FA592_11485	COG2226	methyltransferase
FA592_11500	COG0784	Response regulator, receiver
FA592_11500	COG3437	response regulator, receiver
FA592_11505	COG0840	transmembrane signaling receptor activity
FA592_11515	COG0217	transcriptional regulatory protein
FA592_11525	COG2358	TRAP transporter, solute receptor (TAXI family
FA592_11540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FA592_11565	COG0582	viral genome integration into host DNA
FA592_11590	COG1538	Outer membrane efflux protein
FA592_11595	COG2274	protein secretion by the type I secretion system
FA592_11600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FA592_11665	COG2308	Evidence 4 Homologs of previously reported genes of
FA592_11680	COG2966	Psort location CytoplasmicMembrane, score
FA592_11685	COG3610	response to peptide
FA592_11690	COG2217	Heavy metal translocating P-type atpase
FA592_11710	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FA592_11715	COG2169	Transcriptional regulator
FA592_11715	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FA592_11725	COG0352	thiamine-phosphate diphosphorylase activity
FA592_11740	COG1272	protein, Hemolysin III
FA592_11745	COG1280	lysine exporter protein (LysE YggA)
FA592_11750	COG0697	spore germination
FA592_11770	COG2176	DNA-directed DNA polymerase activity
FA592_11795	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FA592_11805	COG0501	Belongs to the peptidase M48B family
FA592_11825	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FA592_11830	COG2201	protein-glutamate methylesterase activity
FA592_11835	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FA592_11845	COG0133	tryptophan synthase activity
FA592_11850	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FA592_11860	COG0698	ribose 5-phosphate isomerase
FA592_11865	COG1994	Peptidase M50
FA592_11870	COG0681	Belongs to the peptidase S26 family
FA592_11875	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FA592_11885	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FA592_11900	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FA592_11910	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FA592_11940	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FA592_11945	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FA592_11950	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FA592_11955	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FA592_11960	COG0629	single-stranded DNA binding
FA592_11965	COG0360	Binds together with S18 to 16S ribosomal RNA
FA592_11970	COG1466	dna polymerase III delta subunit
FA592_11975	COG0557	exoribonuclease II activity
FA592_11985	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FA592_11990	COG2894	cell division
FA592_11995	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FA592_12000	COG2861	carbohydrate metabolic process
FA592_12010	COG0730	response to heat
FA592_12015	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FA592_12025	COG1760	l-serine dehydratase
FA592_12030	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FA592_12035	COG2860	membrane
FA592_12040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FA592_12055	COG0736	holo-[acyl-carrier-protein] synthase activity
FA592_12060	COG1580	Controls the rotational direction of flagella during chemotaxis
FA592_12065	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FA592_12070	COG0552	protein localization to endoplasmic reticulum
FA592_12075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FA592_12085	COG1418	mRNA catabolic process
FA592_12090	COG1132	(ABC) transporter
FA592_12115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FA592_12125	COG0745	RESPONSE REGULATOR receiver
FA592_12140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FA592_12140	COG4191	Histidine kinase
FA592_12155	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FA592_12215	COG1408	metallophosphoesterase
FA592_12250	COG1136	(ABC) transporter
FA592_12270	COG0546	phosphoglycolate phosphatase activity
FA592_12275	COG1454	alcohol dehydrogenase
FA592_12305	COG0242	peptide deformylase activity
FA592_12310	COG0824	Thioesterase
FA592_12325	COG1573	uracil-dna glycosylase
FA592_12340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FA592_12355	COG0745	RESPONSE REGULATOR receiver
FA592_12360	COG2199	diguanylate cyclase activity
FA592_12360	COG3287	FIST C domain
FA592_12360	COG2200	EAL domain
FA592_12375	COG0426	domain, Protein
FA592_12390	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FA592_12395	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FA592_12400	COG1053	succinate dehydrogenase
FA592_12425	COG2040	homocysteine
FA592_12435	COG1196	nuclear chromosome segregation
FA592_12435	COG3264	Mechanosensitive ion channel
FA592_12440	COG1433	Dinitrogenase iron-molybdenum cofactor
FA592_12475	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FA592_12490	COG0346	lactoylglutathione lyase activity
FA592_12525	COG1451	nucleotide metabolic process
FA592_12545	COG2207	Transcriptional regulator
FA592_12565	COG0697	spore germination
FA592_12575	COG3706	GGDEF domain
FA592_12585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FA592_12600	COG3706	GGDEF domain
FA592_12615	COG0840	transmembrane signaling receptor activity
FA592_12635	COG1276	copper resistance
FA592_12640	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
FA592_12655	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FA592_12660	COG0784	Response regulator, receiver
FA592_12715	COG0642	Histidine kinase
FA592_12720	COG3153	acetyltransferase
FA592_12720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FA592_12750	COG0493	'glutamate synthase
FA592_12755	COG0375	protein maturation
FA592_12760	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FA592_12770	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_12780	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_12815	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FA592_12820	COG0523	cobalamin synthesis protein
FA592_12825	COG2879	small protein
FA592_12830	COG1966	Carbon starvation protein
FA592_12840	COG1053	succinate dehydrogenase
FA592_12875	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FA592_12880	COG0585	pseudouridine synthase activity
FA592_12890	COG0569	domain protein
FA592_12890	COG0475	glutathione-regulated potassium exporter activity
FA592_12905	COG3706	GGDEF domain
FA592_12910	COG0351	phosphomethylpyrimidine kinase
FA592_12920	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FA592_12930	COG0840	transmembrane signaling receptor activity
FA592_12945	COG0488	(ABC) transporter
FA592_12950	COG1360	Flagellar Motor Protein
FA592_12955	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FA592_12960	COG1309	transcriptional regulator
FA592_12990	COG0778	Nitroreductase
FA592_13005	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FA592_13020	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FA592_13030	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FA592_13045	COG4145	pantothenate transmembrane transporter activity
FA592_13060	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FA592_13075	COG0742	ribosomal rna small subunit methyltransferase
FA592_13085	COG1706	bacterial-type flagellum-dependent cell motility
FA592_13090	COG3951	Flagellar rod assembly protein muramidase FlgJ
FA592_13110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FA592_13120	COG0659	secondary active sulfate transmembrane transporter activity
FA592_13125	COG1942	4-Oxalocrotonate Tautomerase
FA592_13130	COG0356	it plays a direct role in the translocation of protons across the membrane
FA592_13140	COG0352	thiamine-phosphate diphosphorylase activity
FA592_13145	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FA592_13155	COG1472	Belongs to the glycosyl hydrolase 3 family
FA592_13160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FA592_13165	COG0101	tRNA pseudouridine synthase activity
FA592_13175	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FA592_13185	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FA592_13190	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FA592_13195	COG1338	Plays a role in the flagellum-specific transport system
FA592_13200	COG0676	glucose-6-phosphate 1-epimerase activity
FA592_13205	COG2249	NAD(P)H dehydrogenase (quinone) activity
FA592_13220	COG3174	membrane
FA592_13225	COG1032	radical SAM domain protein
FA592_13230	COG0166	Belongs to the GPI family
FA592_13250	COG3259	Nickel-dependent hydrogenase
FA592_13255	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FA592_13260	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FA592_13265	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
FA592_13270	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FA592_13275	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FA592_13280	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FA592_13295	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FA592_13300	COG0298	carbon dioxide binding
FA592_13305	COG0409	Hydrogenase expression formation protein
FA592_13310	COG0309	Hydrogenase expression formation protein (HypE)
FA592_13315	COG0375	protein maturation
FA592_13320	COG1247	-acetyltransferase
FA592_13325	COG0546	phosphoglycolate phosphatase activity
FA592_13345	COG0039	L-malate dehydrogenase activity
FA592_13350	COG0045	succinate-CoA ligase (ADP-forming) activity
FA592_13355	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FA592_13365	COG0674	pyruvate-flavodoxin oxidoreductase activity
FA592_13365	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FA592_13460	COG0114	fumarate hydratase activity
FA592_13485	COG0842	Transport permease protein
FA592_13485	COG1129	ABC transporter
FA592_13490	COG0842	Transport permease protein
FA592_13495	COG0842	Transport permease protein
FA592_13500	COG2095	MarC family integral membrane protein
FA592_13520	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FA592_13525	COG0750	zinc metalloprotease
FA592_13530	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FA592_13535	COG1028	Short-chain dehydrogenase reductase Sdr
FA592_13540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FA592_13550	COG0167	dihydroorotate dehydrogenase activity
FA592_13555	COG1132	(ABC) transporter
FA592_13560	COG0215	cysteine-tRNA ligase activity
FA592_13565	COG0728	peptidoglycan biosynthetic process
FA592_13575	COG0632	four-way junction helicase activity
FA592_13595	COG1254	Belongs to the acylphosphatase family
FA592_13600	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FA592_13605	COG0280	phosphate acetyltransferase
FA592_13605	COG0857	belongs to the CobB CobQ family
FA592_13610	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FA592_13615	COG1610	YqeY-like protein
FA592_13675	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FA592_13680	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FA592_13695	COG0137	argininosuccinate synthase activity
FA592_13700	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FA592_13705	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FA592_13710	COG0802	atpase or kinase
FA592_13715	COG1137	ATPase activity
FA592_13815	COG3093	addiction module antidote protein HigA
FA592_13875	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FA592_13945	COG1192	Involved in chromosome partitioning
FA592_13950	COG1192	Involved in chromosome partitioning
FA592_14040	COG3106	COG3106 Predicted ATPase
FA592_14045	COG3106	COG3106 Predicted ATPase
FA592_14050	COG0681	Belongs to the peptidase S26 family
FA592_14060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII