locus-tag	class	description
Sdiek1_0002	COG0592	DNA-directed DNA polymerase activity
Sdiek1_0003	COG0187	DNA topoisomerase II activity
Sdiek1_0004	COG5001	Diguanylate cyclase
Sdiek1_0005	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Sdiek1_0007	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Sdiek1_0008	COG1194	a g-specific adenine glycosylase
Sdiek1_0009	COG4175	Glycine betaine
Sdiek1_0010	COG4176	ABC-type proline glycine betaine transport system permease component
Sdiek1_0011	COG2113	Glycine betaine
Sdiek1_0012	COG2814	Major facilitator Superfamily
Sdiek1_0013	COG0471	metal ion transport
Sdiek1_0014	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Sdiek1_0017	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Sdiek1_0026	COG0840	transmembrane signaling receptor activity
Sdiek1_0030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Sdiek1_0031	COG1335	isochorismatase
Sdiek1_0037	COG1355	regulation of microtubule-based process
Sdiek1_0039	COG2078	PFAM AMMECR1 domain protein
Sdiek1_0044	COG1917	Cupin 2, conserved barrel domain protein
Sdiek1_0044	COG2169	Transcriptional regulator
Sdiek1_0046	COG3150	esterase
Sdiek1_0048	COG3383	formate dehydrogenase (NAD+) activity
Sdiek1_0074	COG0129	dihydroxy-acid dehydratase activity
Sdiek1_0075	COG2095	MarC family integral membrane protein
Sdiek1_0080	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Sdiek1_0081	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Sdiek1_0082	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Sdiek1_0085	COG1328	CTP reductase activity
Sdiek1_0085	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Sdiek1_0086	COG1794	racemase activity, acting on amino acids and derivatives
Sdiek1_0087	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Sdiek1_0088	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Sdiek1_0089	COG0564	pseudouridine synthase activity
Sdiek1_0090	COG0179	Fumarylacetoacetate (FAA) hydrolase
Sdiek1_0091	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Sdiek1_0093	COG0107	imidazoleglycerol-phosphate synthase activity
Sdiek1_0095	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Sdiek1_0096	COG0517	IMP dehydrogenase activity
Sdiek1_0096	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Sdiek1_0097	COG1187	pseudouridine synthase activity
Sdiek1_0098	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Sdiek1_0098	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Sdiek1_0100	COG2257	FlhB HrpN YscU SpaS Family
Sdiek1_0104	COG0237	dephospho-CoA kinase activity
Sdiek1_0105	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Sdiek1_0107	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Sdiek1_0108	COG0268	Binds directly to 16S ribosomal RNA
Sdiek1_0109	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Sdiek1_0110	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Sdiek1_0112	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Sdiek1_0113	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Sdiek1_0114	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Sdiek1_0115	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Sdiek1_0116	COG0348	domain, Protein
Sdiek1_0121	COG0754	glutathionylspermidine amidase activity
Sdiek1_0122	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Sdiek1_0131	COG5002	protein histidine kinase activity
Sdiek1_0132	COG0745	RESPONSE REGULATOR receiver
Sdiek1_0136	COG1127	ABC transporter
Sdiek1_0137	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Sdiek1_0140	COG2095	MarC family integral membrane protein
Sdiek1_0141	COG2095	MarC family integral membrane protein
Sdiek1_0142	COG0840	transmembrane signaling receptor activity
Sdiek1_0144	COG3437	response regulator, receiver
Sdiek1_0144	COG0784	Response regulator, receiver
Sdiek1_0146	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Sdiek1_0148	COG5002	protein histidine kinase activity
Sdiek1_0150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Sdiek1_0152	COG0004	ammonium transporteR
Sdiek1_0153	COG0667	Aldo Keto reductase
Sdiek1_0154	COG0418	dihydroorotase activity
Sdiek1_0155	COG0418	dihydroorotase activity
Sdiek1_0156	COG0745	RESPONSE REGULATOR receiver
Sdiek1_0159	COG0765	amino acid transport
Sdiek1_0167	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Sdiek1_0169	COG0318	PFAM AMP-dependent synthetase and ligase
Sdiek1_0170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Sdiek1_0171	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_0172	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_0173	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_0174	COG0649	NAD binding
Sdiek1_0178	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Sdiek1_0179	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_0180	COG0839	Belongs to the complex I subunit 6 family
Sdiek1_0181	COG0713	ATP synthesis coupled electron transport
Sdiek1_0182	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Sdiek1_0183	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_0184	COG1007	ATP synthesis coupled electron transport
Sdiek1_0186	COG1012	belongs to the aldehyde dehydrogenase family
Sdiek1_0187	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Sdiek1_0191	COG0840	transmembrane signaling receptor activity
Sdiek1_0192	COG0840	transmembrane signaling receptor activity
Sdiek1_0193	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Sdiek1_0194	COG0303	'Molybdopterin
Sdiek1_0196	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Sdiek1_0197	COG0254	rRNA binding
Sdiek1_0198	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Sdiek1_0199	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Sdiek1_0202	COG0436	Aminotransferase
Sdiek1_0203	COG0460	homoserine dehydrogenase
Sdiek1_0204	COG0792	nuclease activity
Sdiek1_0205	COG3118	belongs to the thioredoxin family
Sdiek1_0206	COG0492	ferredoxin-NADP+ reductase activity
Sdiek1_0207	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Sdiek1_0208	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Sdiek1_0209	COG1242	4 iron, 4 sulfur cluster binding
Sdiek1_0212	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Sdiek1_0212	COG0140	phosphoribosyl-ATP diphosphatase activity
Sdiek1_0215	COG1012	belongs to the aldehyde dehydrogenase family
Sdiek1_0216	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Sdiek1_0218	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Sdiek1_0219	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Sdiek1_0220	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Sdiek1_0221	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Sdiek1_0224	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Sdiek1_0228	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Sdiek1_0229	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Sdiek1_0230	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Sdiek1_0231	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Sdiek1_0232	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Sdiek1_0234	COG0784	Response regulator, receiver
Sdiek1_0234	COG0835	chemotaxis
Sdiek1_0235	COG0643	Histidine kinase
Sdiek1_0235	COG2198	Histidine kinase
Sdiek1_0236	COG0835	chemotaxis
Sdiek1_0239	COG0560	Phosphoserine phosphatase
Sdiek1_0243	COG0193	aminoacyl-tRNA hydrolase activity
Sdiek1_0245	COG0019	diaminopimelate decarboxylase activity
Sdiek1_0246	COG0077	Prephenate dehydratase
Sdiek1_0246	COG1605	Chorismate mutase
Sdiek1_0247	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Sdiek1_0249	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Sdiek1_0251	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Sdiek1_0252	COG0735	belongs to the Fur family
Sdiek1_0253	COG0450	alkyl hydroperoxide reductase
Sdiek1_0257	COG0105	UTP biosynthetic process
Sdiek1_0259	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Sdiek1_0260	COG0416	fatty acid biosynthetic process
Sdiek1_0261	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Sdiek1_0262	COG0714	Associated with various cellular activities
Sdiek1_0266	COG2304	oxidoreductase activity
Sdiek1_0268	COG0287	Prephenate dehydrogenase
Sdiek1_0269	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Sdiek1_0271	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Sdiek1_0273	COG0745	RESPONSE REGULATOR receiver
Sdiek1_0275	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Sdiek1_0277	COG0157	Belongs to the NadC ModD family
Sdiek1_0278	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Sdiek1_0281	COG0850	regulation of cytokinetic process
Sdiek1_0282	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Sdiek1_0284	COG0083	homoserine kinase activity
Sdiek1_0286	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Sdiek1_0289	COG0779	Required for maturation of 30S ribosomal subunits
Sdiek1_0290	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Sdiek1_0290	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Sdiek1_0293	COG5001	Diguanylate cyclase
Sdiek1_0294	COG1278	Cold shock
Sdiek1_0295	COG5002	protein histidine kinase activity
Sdiek1_0298	COG3258	Cytochrome c
Sdiek1_0300	COG1242	4 iron, 4 sulfur cluster binding
Sdiek1_0301	COG0243	molybdopterin cofactor binding
Sdiek1_0302	COG0437	4 iron, 4 sulfur cluster binding
Sdiek1_0303	COG3301	Polysulphide reductase, NrfD
Sdiek1_0304	COG3287	FIST C domain
Sdiek1_0304	COG2200	EAL domain
Sdiek1_0304	COG2199	diguanylate cyclase activity
Sdiek1_0306	COG0437	4 iron, 4 sulfur cluster binding
Sdiek1_0307	COG3301	Polysulphide reductase, NrfD
Sdiek1_0308	COG0745	RESPONSE REGULATOR receiver
Sdiek1_0309	COG5002	protein histidine kinase activity
Sdiek1_0311	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Sdiek1_0315	COG0848	biopolymer transport protein
Sdiek1_0316	COG0811	peptide transport
Sdiek1_0320	COG1227	inorganic diphosphatase activity
Sdiek1_0323	COG2226	methyltransferase
Sdiek1_0324	COG1570	exodeoxyribonuclease VII activity
Sdiek1_0329	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Sdiek1_0330	COG1028	Short-chain dehydrogenase reductase Sdr
Sdiek1_0331	COG2207	Transcriptional regulator
Sdiek1_0332	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Sdiek1_0333	COG0583	DNA-binding transcription factor activity
Sdiek1_0334	COG2855	membrane
Sdiek1_0335	COG0386	Belongs to the glutathione peroxidase family
Sdiek1_0336	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Sdiek1_0338	COG0402	S-adenosylhomocysteine deaminase activity
Sdiek1_0339	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Sdiek1_0340	COG0006	proline dipeptidase activity
Sdiek1_0341	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Sdiek1_0342	COG1419	protein localization to endoplasmic reticulum
Sdiek1_0343	COG0455	bacterial-type flagellum organization
Sdiek1_0345	COG1191	sigma factor activity
Sdiek1_0346	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Sdiek1_0348	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Sdiek1_0348	COG1776	CheC inhibitor of MCP methylation
Sdiek1_0350	COG0463	Glycosyl transferase, family 2
Sdiek1_0352	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Sdiek1_0356	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Sdiek1_0358	COG1040	competence protein
Sdiek1_0365	COG2204	response regulator
Sdiek1_0366	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Sdiek1_0368	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Sdiek1_0369	COG0731	radical SAM domain protein
Sdiek1_0373	COG0582	viral genome integration into host DNA
Sdiek1_0374	COG1002	Type II restriction enzyme, methylase subunits
Sdiek1_0377	COG3177	Filamentation induced by cAMP protein fic
Sdiek1_0378	COG1061	Type III restriction enzyme res subunit
Sdiek1_0379	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Sdiek1_0390	COG1464	Belongs to the NlpA lipoprotein family
Sdiek1_0391	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Sdiek1_0392	COG2011	ABC-type metal ion transport system permease component
Sdiek1_0393	COG0306	phosphate transporter
Sdiek1_0394	COG0039	L-malate dehydrogenase activity
Sdiek1_0395	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
Sdiek1_0397	COG1834	amidinotransferase
Sdiek1_0399	COG2207	Transcriptional regulator
Sdiek1_0399	COG3708	Transcriptional regulator
Sdiek1_0400	COG1053	succinate dehydrogenase
Sdiek1_0409	COG2199	diguanylate cyclase activity
Sdiek1_0409	COG3287	FIST C domain
Sdiek1_0409	COG2200	EAL domain
Sdiek1_0413	COG3118	belongs to the thioredoxin family
Sdiek1_0420	COG4628	conserved protein (DUF2132)
Sdiek1_0421	COG4221	oxidoreductase activity
Sdiek1_0422	COG0683	leucine binding
Sdiek1_0423	COG0559	Belongs to the binding-protein-dependent transport system permease family
Sdiek1_0426	COG0410	ABC transporter
Sdiek1_0428	COG3022	response to hydroperoxide
Sdiek1_0433	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Sdiek1_0434	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Sdiek1_0437	COG0250	Participates in transcription elongation, termination and antitermination
Sdiek1_0438	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Sdiek1_0439	COG0081	regulation of translation
Sdiek1_0440	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Sdiek1_0441	COG0222	ribosome binding
Sdiek1_0442	COG0085	RNA polymerase activity
Sdiek1_0443	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Sdiek1_0444	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Sdiek1_0448	COG0697	spore germination
Sdiek1_0449	COG0656	L-ascorbic acid biosynthetic process
Sdiek1_0454	COG0745	RESPONSE REGULATOR receiver
Sdiek1_0457	COG0840	transmembrane signaling receptor activity
Sdiek1_0458	COG0840	transmembrane signaling receptor activity
Sdiek1_0460	COG1034	ATP synthesis coupled electron transport
Sdiek1_0461	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Sdiek1_0462	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_0464	COG0713	ATP synthesis coupled electron transport
Sdiek1_0465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Sdiek1_0466	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_0467	COG1007	ATP synthesis coupled electron transport
Sdiek1_0472	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_0472	COG0649	NAD binding
Sdiek1_0473	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_0474	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_0477	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Sdiek1_0481	COG0357	Ribosomal RNA small subunit methyltransferase G
Sdiek1_0482	COG0840	transmembrane signaling receptor activity
Sdiek1_0482	COG3290	protein histidine kinase activity
Sdiek1_0484	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Sdiek1_0485	COG1970	mechanosensitive ion channel activity
Sdiek1_0487	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Sdiek1_0488	COG0113	porphobilinogen synthase activity
Sdiek1_0489	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Sdiek1_0491	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Sdiek1_0492	COG0247	lactate metabolic process
Sdiek1_0498	COG3706	GGDEF domain
Sdiek1_0498	COG0745	RESPONSE REGULATOR receiver
Sdiek1_0500	COG3012	SEC-C Motif Domain Protein
Sdiek1_0503	COG3706	GGDEF domain
Sdiek1_0504	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Sdiek1_0506	COG1053	succinate dehydrogenase
Sdiek1_0507	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Sdiek1_0509	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Sdiek1_0510	COG0628	permease
Sdiek1_0511	COG2255	four-way junction helicase activity
Sdiek1_0512	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Sdiek1_0514	COG0159	tryptophan synthase activity
Sdiek1_0519	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Sdiek1_0520	COG1136	(ABC) transporter
Sdiek1_0521	COG1684	flagellar biosynthetic protein fliR
Sdiek1_0523	COG0194	GDP metabolic process
Sdiek1_0524	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Sdiek1_0525	COG0018	arginyl-trna synthetase
Sdiek1_0527	COG2199	diguanylate cyclase activity
Sdiek1_0527	COG2200	EAL domain
Sdiek1_0527	COG3287	FIST C domain
Sdiek1_0531	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Sdiek1_0532	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Sdiek1_0534	COG0149	triose-phosphate isomerase activity
Sdiek1_0535	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Sdiek1_0537	COG0195	Participates in both transcription termination and antitermination
Sdiek1_0544	COG0037	tRNA processing
Sdiek1_0545	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Sdiek1_0546	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Sdiek1_0547	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Sdiek1_0552	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Sdiek1_0553	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Sdiek1_0554	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Sdiek1_0556	COG1151	hydroxylamine reductase activity
Sdiek1_0557	COG3040	lipid binding
Sdiek1_0558	COG1401	restriction endodeoxyribonuclease activity
Sdiek1_0562	COG2326	polyphosphate kinase activity
Sdiek1_0566	COG0723	plastoquinol--plastocyanin reductase activity
Sdiek1_0567	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Sdiek1_0570	COG0513	Belongs to the DEAD box helicase family
Sdiek1_0571	COG2610	gluconate transmembrane transporter activity
Sdiek1_0572	COG1944	ATP diphosphatase activity
Sdiek1_0575	COG4191	Histidine kinase
Sdiek1_0576	COG0745	RESPONSE REGULATOR receiver
Sdiek1_0583	COG0411	ABC transporter
Sdiek1_0585	COG1333	cytochrome c biogenesis protein
Sdiek1_0585	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Sdiek1_0593	COG1546	Belongs to the CinA family
Sdiek1_0593	COG1058	Belongs to the CinA family
Sdiek1_0594	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Sdiek1_0597	COG0517	IMP dehydrogenase activity
Sdiek1_0597	COG0516	GMP reductase activity
Sdiek1_0598	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Sdiek1_0601	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Sdiek1_0602	COG0436	Aminotransferase
Sdiek1_0605	COG1193	negative regulation of DNA recombination
Sdiek1_0606	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Sdiek1_0607	COG0251	oxidation-reduction process
Sdiek1_0608	COG0579	oxidoreductase
Sdiek1_0609	COG2226	methyltransferase
Sdiek1_0612	COG0793	Belongs to the peptidase S41A family
Sdiek1_0612	COG3409	Peptidoglycan-binding domain 1 protein
Sdiek1_0616	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Sdiek1_0617	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Sdiek1_0618	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Sdiek1_0619	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Sdiek1_0620	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Sdiek1_0622	COG1192	Involved in chromosome partitioning
Sdiek1_0623	COG1475	DNA binding
Sdiek1_0626	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Sdiek1_0627	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Sdiek1_0629	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Sdiek1_0632	COG0811	peptide transport
Sdiek1_0633	COG0848	biopolymer transport protein
Sdiek1_0635	COG0823	Involved in the tonB-independent uptake of proteins
Sdiek1_0636	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Sdiek1_0636	COG2885	chlorophyll binding
Sdiek1_0638	COG1047	Peptidyl-prolyl cis-trans
Sdiek1_0640	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Sdiek1_0641	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Sdiek1_0642	COG0037	tRNA processing
Sdiek1_0644	COG0070	glutamate synthase
Sdiek1_0644	COG0067	glutamate synthase
Sdiek1_0644	COG0069	glutamate synthase activity
Sdiek1_0645	COG0493	'glutamate synthase
Sdiek1_0647	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Sdiek1_0648	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Sdiek1_0649	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Sdiek1_0651	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Sdiek1_0655	COG1776	CheC inhibitor of MCP methylation
Sdiek1_0655	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Sdiek1_0665	COG0748	coenzyme F420 binding
Sdiek1_0668	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Sdiek1_0670	COG0454	-acetyltransferase
Sdiek1_0672	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Sdiek1_0674	COG1113	amino acid transport
Sdiek1_0675	COG0730	response to heat
Sdiek1_0676	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Sdiek1_0677	COG1301	dicarboxylic acid transport
Sdiek1_0678	COG1301	dicarboxylic acid transport
Sdiek1_0680	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Sdiek1_0680	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Sdiek1_0681	COG1971	Probably functions as a manganese efflux pump
Sdiek1_0684	COG0484	heat shock protein binding
Sdiek1_0686	COG0745	RESPONSE REGULATOR receiver
Sdiek1_0688	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Sdiek1_0691	COG0318	PFAM AMP-dependent synthetase and ligase
Sdiek1_0692	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Sdiek1_0693	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Sdiek1_0696	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Sdiek1_0697	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Sdiek1_0700	COG3706	GGDEF domain
Sdiek1_0702	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Sdiek1_0706	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Sdiek1_0709	COG2205	protein histidine kinase activity
Sdiek1_0709	COG0784	Response regulator, receiver
Sdiek1_0709	COG5002	protein histidine kinase activity
Sdiek1_0712	COG0322	excinuclease ABC activity
Sdiek1_0714	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Sdiek1_0715	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Sdiek1_0716	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Sdiek1_0716	COG0519	Catalyzes the synthesis of GMP from XMP
Sdiek1_0718	COG0151	Belongs to the GarS family
Sdiek1_0720	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Sdiek1_0722	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Sdiek1_0726	COG0511	ligase activity, forming carbon-carbon bonds
Sdiek1_0727	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Sdiek1_0728	COG0165	Argininosuccinate lyase
Sdiek1_0729	COG0537	adenosine 5'-monophosphoramidase activity
Sdiek1_0730	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Sdiek1_0731	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Sdiek1_0731	COG0072	phenylalanine-tRNA ligase activity
Sdiek1_0732	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Sdiek1_0733	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Sdiek1_0734	COG0539	negative regulation of cytoplasmic translation
Sdiek1_0734	COG1185	polyribonucleotide nucleotidyltransferase activity
Sdiek1_0736	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Sdiek1_0738	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Sdiek1_0740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Sdiek1_0744	COG0840	transmembrane signaling receptor activity
Sdiek1_0746	COG0840	transmembrane signaling receptor activity
Sdiek1_0748	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Sdiek1_0751	COG2081	HI0933 family
Sdiek1_0756	COG1902	pentaerythritol trinitrate reductase activity
Sdiek1_0757	COG1538	Outer membrane efflux protein
Sdiek1_0759	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Sdiek1_0760	COG0840	transmembrane signaling receptor activity
Sdiek1_0761	COG0840	transmembrane signaling receptor activity
Sdiek1_0761	COG0840	transmembrane signaling receptor activity
Sdiek1_0763	COG0587	DNA-directed DNA polymerase activity
Sdiek1_0766	COG1346	cytolysis
Sdiek1_0767	COG1380	Effector of murein hydrolase LrgA
Sdiek1_0771	COG0772	Belongs to the SEDS family
Sdiek1_0772	COG0564	pseudouridine synthase activity
Sdiek1_0774	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Sdiek1_0779	COG0528	UMP kinase activity
Sdiek1_0780	COG1758	RNA polymerase activity
Sdiek1_0781	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Sdiek1_0782	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Sdiek1_0783	COG2070	2-Nitropropane dioxygenase
Sdiek1_0784	COG0860	N-Acetylmuramoyl-L-alanine amidase
Sdiek1_0786	COG0563	adenylate kinase activity
Sdiek1_0787	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Sdiek1_0788	COG3706	GGDEF domain
Sdiek1_0790	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Sdiek1_0791	COG0497	DNA recombination
Sdiek1_0793	COG0084	hydrolase, TatD family'
Sdiek1_0794	COG3942	CHAP domain
Sdiek1_0794	COG1388	LysM domain
Sdiek1_0795	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Sdiek1_0796	COG0131	Imidazoleglycerol-phosphate dehydratase
Sdiek1_0797	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Sdiek1_0800	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Sdiek1_0803	COG0768	penicillin binding
Sdiek1_0806	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Sdiek1_0808	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Sdiek1_0808	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Sdiek1_0810	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Sdiek1_0815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Sdiek1_0816	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Sdiek1_0820	COG0471	metal ion transport
Sdiek1_0821	COG4191	Histidine kinase
Sdiek1_0823	COG0840	transmembrane signaling receptor activity
Sdiek1_0825	COG0583	DNA-binding transcription factor activity
Sdiek1_0826	COG1053	succinate dehydrogenase
Sdiek1_0827	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Sdiek1_0828	COG2048	Heterodisulfide reductase, subunit B
Sdiek1_0830	COG3290	protein histidine kinase activity
Sdiek1_0830	COG0840	transmembrane signaling receptor activity
Sdiek1_0833	COG3005	denitrification pathway
Sdiek1_0834	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
Sdiek1_0835	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Sdiek1_0835	COG1333	cytochrome c biogenesis protein
Sdiek1_0839	COG3545	Serine hydrolase
Sdiek1_0841	COG0463	Glycosyl transferase, family 2
Sdiek1_0842	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
Sdiek1_0844	COG0398	Pfam SNARE associated Golgi protein
Sdiek1_0847	COG0398	Pfam SNARE associated Golgi protein
Sdiek1_0848	COG2226	methyltransferase
Sdiek1_0853	COG1575	Belongs to the MenA family. Type 1 subfamily
Sdiek1_0855	COG0300	oxidoreductase activity
Sdiek1_0858	COG4716	Myosin-crossreactive antigen
Sdiek1_0864	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Sdiek1_0869	COG0243	molybdopterin cofactor binding
Sdiek1_0870	COG0437	4 iron, 4 sulfur cluster binding
Sdiek1_0871	COG0348	domain, Protein
Sdiek1_0872	COG3043	anaerobic respiration
Sdiek1_0873	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Sdiek1_0873	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
Sdiek1_0879	COG1342	Belongs to the UPF0251 family
Sdiek1_0883	COG1271	oxidase subunit
Sdiek1_0884	COG1294	oxidase, subunit
Sdiek1_0890	COG0243	molybdopterin cofactor binding
Sdiek1_0893	COG0745	RESPONSE REGULATOR receiver
Sdiek1_0895	COG4191	Histidine kinase
Sdiek1_0900	COG2863	cytochrome
Sdiek1_0901	COG0723	plastoquinol--plastocyanin reductase activity
Sdiek1_0902	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Sdiek1_0905	COG3287	FIST C domain
Sdiek1_0905	COG2200	EAL domain
Sdiek1_0905	COG2199	diguanylate cyclase activity
Sdiek1_0907	COG0513	Belongs to the DEAD box helicase family
Sdiek1_0910	COG2084	Dehydrogenase
Sdiek1_0911	COG0840	transmembrane signaling receptor activity
Sdiek1_0911	COG3290	protein histidine kinase activity
Sdiek1_0912	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Sdiek1_0913	COG2226	methyltransferase
Sdiek1_0916	COG0784	Response regulator, receiver
Sdiek1_0916	COG3437	response regulator, receiver
Sdiek1_0921	COG0217	transcriptional regulatory protein
Sdiek1_0926	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Sdiek1_0931	COG3706	GGDEF domain
Sdiek1_0931	COG0745	RESPONSE REGULATOR receiver
Sdiek1_0970	COG1136	(ABC) transporter
Sdiek1_0975	COG0348	domain, Protein
Sdiek1_0978	COG0437	4 iron, 4 sulfur cluster binding
Sdiek1_0981	COG4263	nitrous-oxide reductase activity
Sdiek1_0982	COG3852	Histidine kinase
Sdiek1_0983	COG2207	Transcriptional regulator
Sdiek1_0983	COG4753	response regulator
Sdiek1_0984	COG2863	cytochrome
Sdiek1_0985	COG0723	plastoquinol--plastocyanin reductase activity
Sdiek1_0986	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Sdiek1_0987	COG2857	Cytochrome c1
Sdiek1_0990	COG2199	diguanylate cyclase activity
Sdiek1_0990	COG2200	EAL domain
Sdiek1_0990	COG3287	FIST C domain
Sdiek1_0992	COG0840	transmembrane signaling receptor activity
Sdiek1_1007	COG0243	molybdopterin cofactor binding
Sdiek1_1010	COG4191	Histidine kinase
Sdiek1_1012	COG1136	(ABC) transporter
Sdiek1_1013	COG0577	efflux transmembrane transporter activity
Sdiek1_1013	COG1136	(ABC) transporter
Sdiek1_1020	COG3842	ATPase activity
Sdiek1_1022	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Sdiek1_1026	COG0243	molybdopterin cofactor binding
Sdiek1_1027	COG0243	molybdopterin cofactor binding
Sdiek1_1029	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Sdiek1_1030	COG0640	Transcriptional regulator
Sdiek1_1031	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Sdiek1_1034	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Sdiek1_1035	COG4232	protein-disulfide reductase activity
Sdiek1_1047	COG1538	Outer membrane efflux protein
Sdiek1_1057	COG0840	transmembrane signaling receptor activity
Sdiek1_1057	COG3290	protein histidine kinase activity
Sdiek1_1058	COG3045	CreA protein
Sdiek1_1059	COG2226	methyltransferase
Sdiek1_1061	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Sdiek1_1064	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Sdiek1_1065	COG0651	ATP synthesis coupled electron transport
Sdiek1_1066	COG0650	Formate hydrogenlyase subunit 4
Sdiek1_1067	COG4237	Hydrogenase 4 membrane
Sdiek1_1068	COG0651	ATP synthesis coupled electron transport
Sdiek1_1069	COG3261	NADH dehydrogenase
Sdiek1_1069	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
Sdiek1_1071	COG3260	NADH ubiquinone oxidoreductase 20
Sdiek1_1074	COG2116	formate transmembrane transporter activity
Sdiek1_1077	COG0745	RESPONSE REGULATOR receiver
Sdiek1_1078	COG4191	Histidine kinase
Sdiek1_1079	COG0484	heat shock protein binding
Sdiek1_1080	COG0545	Peptidyl-prolyl cis-trans isomerase
Sdiek1_1081	COG0437	4 iron, 4 sulfur cluster binding
Sdiek1_1082	COG3301	Polysulphide reductase, NrfD
Sdiek1_1083	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Sdiek1_1083	COG1333	cytochrome c biogenesis protein
Sdiek1_1096	COG0745	RESPONSE REGULATOR receiver
Sdiek1_1098	COG2205	protein histidine kinase activity
Sdiek1_1099	COG3279	Response regulator of the LytR AlgR family
Sdiek1_1100	COG3275	phosphorelay sensor kinase activity
Sdiek1_1102	COG1538	Outer membrane efflux protein
Sdiek1_1103	COG2274	protein secretion by the type I secretion system
Sdiek1_1105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Sdiek1_1119	COG2308	Evidence 4 Homologs of previously reported genes of
Sdiek1_1122	COG2966	Psort location CytoplasmicMembrane, score
Sdiek1_1123	COG3610	response to peptide
Sdiek1_1124	COG2217	Heavy metal translocating P-type atpase
Sdiek1_1127	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Sdiek1_1128	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Sdiek1_1128	COG2169	Transcriptional regulator
Sdiek1_1130	COG0352	thiamine-phosphate diphosphorylase activity
Sdiek1_1131	COG0352	thiamine-phosphate diphosphorylase activity
Sdiek1_1134	COG1272	protein, Hemolysin III
Sdiek1_1137	COG0697	spore germination
Sdiek1_1160	COG2176	DNA-directed DNA polymerase activity
Sdiek1_1161	COG0798	PFAM Bile acid sodium symporter
Sdiek1_1162	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Sdiek1_1164	COG0501	Belongs to the peptidase M48B family
Sdiek1_1168	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Sdiek1_1169	COG2201	protein-glutamate methylesterase activity
Sdiek1_1170	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Sdiek1_1172	COG0133	tryptophan synthase activity
Sdiek1_1173	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Sdiek1_1175	COG0698	ribose 5-phosphate isomerase
Sdiek1_1176	COG1994	Peptidase M50
Sdiek1_1177	COG0681	Belongs to the peptidase S26 family
Sdiek1_1178	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Sdiek1_1180	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Sdiek1_1183	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Sdiek1_1184	COG0612	Peptidase, M16
Sdiek1_1185	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Sdiek1_1186	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Sdiek1_1194	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
Sdiek1_1195	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Sdiek1_1197	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Sdiek1_1198	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Sdiek1_1199	COG0629	single-stranded DNA binding
Sdiek1_1200	COG0360	Binds together with S18 to 16S ribosomal RNA
Sdiek1_1201	COG1466	dna polymerase III delta subunit
Sdiek1_1202	COG0557	exoribonuclease II activity
Sdiek1_1204	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Sdiek1_1205	COG2894	cell division
Sdiek1_1206	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Sdiek1_1207	COG2861	carbohydrate metabolic process
Sdiek1_1209	COG0730	response to heat
Sdiek1_1210	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Sdiek1_1212	COG1760	l-serine dehydratase
Sdiek1_1213	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Sdiek1_1214	COG2860	membrane
Sdiek1_1215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Sdiek1_1218	COG0736	holo-[acyl-carrier-protein] synthase activity
Sdiek1_1219	COG1580	Controls the rotational direction of flagella during chemotaxis
Sdiek1_1220	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Sdiek1_1221	COG0552	protein localization to endoplasmic reticulum
Sdiek1_1222	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Sdiek1_1223	COG1418	mRNA catabolic process
Sdiek1_1224	COG1132	(ABC) transporter
Sdiek1_1230	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Sdiek1_1233	COG0745	RESPONSE REGULATOR receiver
Sdiek1_1235	COG5001	Diguanylate cyclase
Sdiek1_1235	COG5002	protein histidine kinase activity
Sdiek1_1238	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Sdiek1_1250	COG1408	metallophosphoesterase
Sdiek1_1251	COG2353	YceI-like domain
Sdiek1_1255	COG1136	(ABC) transporter
Sdiek1_1262	COG1454	alcohol dehydrogenase
Sdiek1_1270	COG0242	peptide deformylase activity
Sdiek1_1271	COG0824	Thioesterase
Sdiek1_1274	COG1573	uracil-dna glycosylase
Sdiek1_1277	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Sdiek1_1281	COG2199	diguanylate cyclase activity
Sdiek1_1281	COG3287	FIST C domain
Sdiek1_1281	COG2200	EAL domain
Sdiek1_1284	COG0426	domain, Protein
Sdiek1_1289	COG3976	FMN-binding domain protein
Sdiek1_1289	COG1053	succinate dehydrogenase
Sdiek1_1294	COG2040	homocysteine
Sdiek1_1296	COG3264	Mechanosensitive ion channel
Sdiek1_1296	COG1196	nuclear chromosome segregation
Sdiek1_1297	COG1433	Dinitrogenase iron-molybdenum cofactor
Sdiek1_1299	COG0716	FMN binding
Sdiek1_1304	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Sdiek1_1307	COG0346	lactoylglutathione lyase activity
Sdiek1_1311	COG5001	Diguanylate cyclase
Sdiek1_1311	COG2203	Gaf domain
Sdiek1_1311	COG3706	GGDEF domain
Sdiek1_1311	COG4251	negative regulation of phosphorylation
Sdiek1_1317	COG1451	nucleotide metabolic process
Sdiek1_1324	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Sdiek1_1329	COG0697	spore germination
Sdiek1_1331	COG3706	GGDEF domain
Sdiek1_1338	COG0840	transmembrane signaling receptor activity
Sdiek1_1340	COG1276	copper resistance
Sdiek1_1341	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
Sdiek1_1346	COG5002	protein histidine kinase activity
Sdiek1_1347	COG0745	RESPONSE REGULATOR receiver
Sdiek1_1349	COG3153	acetyltransferase
Sdiek1_1349	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Sdiek1_1357	COG4565	transcriptional regulatory protein
Sdiek1_1359	COG5002	protein histidine kinase activity
Sdiek1_1363	COG0493	'glutamate synthase
Sdiek1_1364	COG0375	protein maturation
Sdiek1_1365	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Sdiek1_1367	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_1369	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_1373	COG1335	isochorismatase
Sdiek1_1377	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Sdiek1_1378	COG0523	cobalamin synthesis protein
Sdiek1_1379	COG2879	small protein
Sdiek1_1380	COG1966	Carbon starvation protein
Sdiek1_1383	COG1053	succinate dehydrogenase
Sdiek1_1390	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Sdiek1_1391	COG0585	pseudouridine synthase activity
Sdiek1_1392	COG0569	domain protein
Sdiek1_1392	COG0475	glutathione-regulated potassium exporter activity
Sdiek1_1395	COG3706	GGDEF domain
Sdiek1_1396	COG0351	phosphomethylpyrimidine kinase
Sdiek1_1396	COG0352	thiamine-phosphate diphosphorylase activity
Sdiek1_1398	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
Sdiek1_1400	COG0840	transmembrane signaling receptor activity
Sdiek1_1401	COG1234	tRNA 3'-trailer cleavage
Sdiek1_1403	COG0488	(ABC) transporter
Sdiek1_1404	COG1360	Flagellar Motor Protein
Sdiek1_1405	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Sdiek1_1410	COG1538	Outer membrane efflux protein
Sdiek1_1414	COG0778	Nitroreductase
Sdiek1_1422	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Sdiek1_1426	COG4145	pantothenate transmembrane transporter activity
Sdiek1_1429	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Sdiek1_1432	COG0742	ribosomal rna small subunit methyltransferase
Sdiek1_1434	COG1706	bacterial-type flagellum-dependent cell motility
Sdiek1_1435	COG3951	Flagellar rod assembly protein muramidase FlgJ
Sdiek1_1438	COG1256	bacterial-type flagellum assembly
Sdiek1_1439	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Sdiek1_1441	COG0659	secondary active sulfate transmembrane transporter activity
Sdiek1_1442	COG1942	4-Oxalocrotonate Tautomerase
Sdiek1_1443	COG0356	it plays a direct role in the translocation of protons across the membrane
Sdiek1_1445	COG0352	thiamine-phosphate diphosphorylase activity
Sdiek1_1446	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Sdiek1_1448	COG1472	Belongs to the glycosyl hydrolase 3 family
Sdiek1_1450	COG0101	tRNA pseudouridine synthase activity
Sdiek1_1452	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Sdiek1_1455	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Sdiek1_1456	COG1338	Plays a role in the flagellum-specific transport system
Sdiek1_1457	COG0676	glucose-6-phosphate 1-epimerase activity
Sdiek1_1458	COG2249	NAD(P)H dehydrogenase (quinone) activity
Sdiek1_1461	COG3174	membrane
Sdiek1_1462	COG1032	radical SAM domain protein
Sdiek1_1463	COG0166	Belongs to the GPI family
Sdiek1_1467	COG3259	Nickel-dependent hydrogenase
Sdiek1_1468	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
Sdiek1_1469	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
Sdiek1_1470	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
Sdiek1_1471	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Sdiek1_1472	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Sdiek1_1473	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Sdiek1_1476	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Sdiek1_1477	COG0298	carbon dioxide binding
Sdiek1_1478	COG0409	Hydrogenase expression formation protein
Sdiek1_1479	COG0309	Hydrogenase expression formation protein (HypE)
Sdiek1_1480	COG0375	protein maturation
Sdiek1_1481	COG1247	-acetyltransferase
Sdiek1_1482	COG0546	phosphoglycolate phosphatase activity
Sdiek1_1487	COG0039	L-malate dehydrogenase activity
Sdiek1_1488	COG0045	succinate-CoA ligase (ADP-forming) activity
Sdiek1_1489	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Sdiek1_1491	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Sdiek1_1491	COG0674	pyruvate-flavodoxin oxidoreductase activity
Sdiek1_1492	COG3962	Belongs to the TPP enzyme family
Sdiek1_1497	COG4565	transcriptional regulatory protein
Sdiek1_1501	COG0114	fumarate hydratase activity
Sdiek1_1506	COG1129	ABC transporter
Sdiek1_1506	COG0842	Transport permease protein
Sdiek1_1507	COG0842	Transport permease protein
Sdiek1_1508	COG0842	Transport permease protein
Sdiek1_1509	COG2095	MarC family integral membrane protein
Sdiek1_1512	COG3706	GGDEF domain
Sdiek1_1512	COG0745	RESPONSE REGULATOR receiver
Sdiek1_1513	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Sdiek1_1514	COG0750	zinc metalloprotease
Sdiek1_1515	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Sdiek1_1516	COG1028	Short-chain dehydrogenase reductase Sdr
Sdiek1_1517	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Sdiek1_1519	COG0167	dihydroorotate dehydrogenase activity
Sdiek1_1520	COG1132	(ABC) transporter
Sdiek1_1521	COG0215	cysteine-tRNA ligase activity
Sdiek1_1522	COG0728	peptidoglycan biosynthetic process
Sdiek1_1524	COG0632	four-way junction helicase activity
Sdiek1_1525	COG1181	Belongs to the D-alanine--D-alanine ligase family
Sdiek1_1528	COG1254	Belongs to the acylphosphatase family
Sdiek1_1529	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Sdiek1_1530	COG0857	belongs to the CobB CobQ family
Sdiek1_1530	COG0280	phosphate acetyltransferase
Sdiek1_1531	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Sdiek1_1532	COG1610	YqeY-like protein
Sdiek1_1547	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Sdiek1_1548	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Sdiek1_1551	COG0137	argininosuccinate synthase activity
Sdiek1_1552	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Sdiek1_1553	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Sdiek1_1554	COG0802	atpase or kinase
Sdiek1_1555	COG1137	ATPase activity
Sdiek1_1556	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Sdiek1_1561	COG0419	ATPase involved in DNA repair
Sdiek1_1564	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
Sdiek1_1579	COG2201	protein-glutamate methylesterase activity
Sdiek1_1582	COG1053	succinate dehydrogenase
Sdiek1_1590	COG3852	Histidine kinase
Sdiek1_1594	COG4191	Histidine kinase
Sdiek1_1594	COG0784	Response regulator, receiver
Sdiek1_1595	COG0745	RESPONSE REGULATOR receiver
Sdiek1_1597	COG0437	4 iron, 4 sulfur cluster binding
Sdiek1_1600	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Sdiek1_1602	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
Sdiek1_1606	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Sdiek1_1610	COG1120	ATPase activity
Sdiek1_1613	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
Sdiek1_1617	COG2875	Belongs to the precorrin methyltransferase family
Sdiek1_1622	COG1132	(ABC) transporter
Sdiek1_1623	COG1797	cobyrinic acid a,c-diamide synthase activity
Sdiek1_1625	COG1648	precorrin-2 dehydrogenase activity
Sdiek1_1625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Sdiek1_1647	COG0582	viral genome integration into host DNA
Sdiek1_1649	COG0776	regulation of translation
Sdiek1_1652	COG1196	nuclear chromosome segregation
Sdiek1_1652	COG1674	ftsk spoiiie
Sdiek1_1653	COG1049	propionate catabolic process, 2-methylcitrate cycle
Sdiek1_1654	COG1047	Peptidyl-prolyl cis-trans
Sdiek1_1655	COG0574	Belongs to the PEP-utilizing enzyme family
Sdiek1_1655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Sdiek1_1656	COG3713	MltA-interacting MipA family protein
Sdiek1_1658	COG2814	Major facilitator Superfamily
Sdiek1_1662	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Sdiek1_1663	COG0840	transmembrane signaling receptor activity
Sdiek1_1664	COG1832	CoA-binding protein
Sdiek1_1665	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Sdiek1_1667	COG1126	abc transporter atp-binding protein
Sdiek1_1668	COG0765	amino acid transport
Sdiek1_1669	COG4597	amino acid ABC transporter
Sdiek1_1670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Sdiek1_1671	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Sdiek1_1673	COG0586	Pfam SNARE associated Golgi protein
Sdiek1_1674	COG1136	(ABC) transporter
Sdiek1_1674	COG0577	efflux transmembrane transporter activity
Sdiek1_1675	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Sdiek1_1680	COG0727	PFAM Uncharacterised protein family (UPF0153)
Sdiek1_1682	COG0134	indole-3-glycerol-phosphate synthase activity
Sdiek1_1684	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
Sdiek1_1685	COG1122	ATPase activity
Sdiek1_1688	COG0310	cobalt ion transport
Sdiek1_1689	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Sdiek1_1690	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Sdiek1_1693	COG0446	pyridine nucleotide-disulphide oxidoreductase
Sdiek1_1696	COG0028	Belongs to the TPP enzyme family
Sdiek1_1697	COG0440	acetolactate synthase activity
Sdiek1_1698	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Sdiek1_1700	COG0493	'glutamate synthase
Sdiek1_1702	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Sdiek1_1708	COG1045	serine acetyltransferase
Sdiek1_1709	COG1166	arginine decarboxylase activity
Sdiek1_1710	COG0124	histidyl-tRNA synthetase
Sdiek1_1713	COG0163	prenyltransferase activity
Sdiek1_1717	COG0303	'Molybdopterin
Sdiek1_1718	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Sdiek1_1721	COG1691	(AIR) carboxylase
Sdiek1_1722	COG1606	tRNA processing
Sdiek1_1723	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Sdiek1_1724	COG3875	lactate racemase activity
Sdiek1_1725	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Sdiek1_1725	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
Sdiek1_1727	COG0471	metal ion transport
Sdiek1_1730	COG0745	RESPONSE REGULATOR receiver
Sdiek1_1733	COG0588	phosphoglycerate mutase activity
Sdiek1_1735	COG0582	viral genome integration into host DNA
Sdiek1_1736	COG0343	queuine tRNA-ribosyltransferase activity
Sdiek1_1738	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Sdiek1_1740	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Sdiek1_1741	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Sdiek1_1745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Sdiek1_1746	COG1187	pseudouridine synthase activity
Sdiek1_1748	COG0028	Belongs to the TPP enzyme family
Sdiek1_1754	COG1309	transcriptional regulator
Sdiek1_1762	COG3290	protein histidine kinase activity
Sdiek1_1762	COG0840	transmembrane signaling receptor activity
Sdiek1_1763	COG1592	Rubrerythrin
Sdiek1_1765	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Sdiek1_1766	COG0181	hydroxymethylbilane synthase activity
Sdiek1_1768	COG3030	protein affecting phage T7 exclusion by the F plasmid
Sdiek1_1769	COG0442	prolyl-tRNA aminoacylation
Sdiek1_1770	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Sdiek1_1771	COG0142	geranyltranstransferase activity
Sdiek1_1775	COG1959	2 iron, 2 sulfur cluster binding
Sdiek1_1777	COG3706	GGDEF domain
Sdiek1_1778	COG0525	valine-tRNA ligase activity
Sdiek1_1779	COG0521	Mo-molybdopterin cofactor biosynthetic process
Sdiek1_1780	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Sdiek1_1781	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Sdiek1_1784	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Sdiek1_1785	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Sdiek1_1787	COG2195	Cleaves the N-terminal amino acid of tripeptides
Sdiek1_1789	COG0500	methyltransferase
Sdiek1_1792	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Sdiek1_1793	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Sdiek1_1794	COG1663	tetraacyldisaccharide 4'-kinase activity
Sdiek1_1795	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Sdiek1_1796	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Sdiek1_1797	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Sdiek1_1799	COG4232	protein-disulfide reductase activity
Sdiek1_1801	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Sdiek1_1802	COG0443	Heat shock 70 kDa protein
Sdiek1_1803	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Sdiek1_1804	COG1420	regulation of RNA biosynthetic process
Sdiek1_1807	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Sdiek1_1808	COG1959	2 iron, 2 sulfur cluster binding
Sdiek1_1809	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Sdiek1_1810	COG2404	hydrolase activity, acting on ester bonds
Sdiek1_1812	COG2226	methyltransferase
Sdiek1_1813	COG2199	diguanylate cyclase activity
Sdiek1_1813	COG2203	Gaf domain
Sdiek1_1814	COG0196	riboflavin kinase activity
Sdiek1_1815	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Sdiek1_1816	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Sdiek1_1817	COG0730	response to heat
Sdiek1_1819	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Sdiek1_1822	COG0527	aspartate kinase activity
Sdiek1_1823	COG0494	nUDIX hydrolase
Sdiek1_1824	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Sdiek1_1825	COG0475	glutathione-regulated potassium exporter activity
Sdiek1_1825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Sdiek1_1826	COG0789	Transcriptional regulator
Sdiek1_1827	COG0484	heat shock protein binding
Sdiek1_1829	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Sdiek1_1830	COG0745	RESPONSE REGULATOR receiver
Sdiek1_1831	COG2205	protein histidine kinase activity
Sdiek1_1834	COG0653	protein targeting
Sdiek1_1835	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Sdiek1_1837	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Sdiek1_1838	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Sdiek1_1840	COG0706	membrane insertase activity
Sdiek1_1841	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Sdiek1_1842	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Sdiek1_1845	COG4865	methylaspartate mutase activity
Sdiek1_1848	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Sdiek1_1851	COG0542	response to heat
Sdiek1_1852	COG0793	Belongs to the peptidase S41A family
Sdiek1_1854	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Sdiek1_1855	COG0047	phosphoribosylformylglycinamidine synthase activity
Sdiek1_1857	COG0204	Acyl-transferase
Sdiek1_1858	COG0326	Molecular chaperone. Has ATPase activity
Sdiek1_1860	COG1331	Highly conserved protein containing a thioredoxin domain
Sdiek1_1861	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Sdiek1_1869	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Sdiek1_1872	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Sdiek1_1874	COG2608	mercury ion transmembrane transporter activity
Sdiek1_1875	COG2217	Heavy metal translocating P-type atpase
Sdiek1_1876	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Sdiek1_1879	COG0275	rRNA processing
Sdiek1_1881	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Sdiek1_1882	COG0849	cell division
Sdiek1_1883	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Sdiek1_1885	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Sdiek1_1885	COG2890	protein-(glutamine-N5) methyltransferase activity
Sdiek1_1886	COG0501	Belongs to the peptidase M48B family
Sdiek1_1890	COG0840	transmembrane signaling receptor activity
Sdiek1_1892	COG2151	metal-sulfur cluster biosynthetic enzyme
Sdiek1_1895	COG0138	bifunctional purine biosynthesis protein purh
Sdiek1_1896	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Sdiek1_1898	COG1607	acyl-coa hydrolase
Sdiek1_1899	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Sdiek1_1900	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Sdiek1_1905	COG1694	Mazg nucleotide pyrophosphohydrolase
Sdiek1_1906	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Sdiek1_1907	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Sdiek1_1910	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Sdiek1_1911	COG0805	protein transport
Sdiek1_1912	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Sdiek1_1919	COG3437	response regulator, receiver
Sdiek1_1920	COG3437	response regulator, receiver
Sdiek1_1920	COG3850	Histidine kinase
Sdiek1_1920	COG4999	Histidine kinase
Sdiek1_1920	COG2205	protein histidine kinase activity
Sdiek1_1921	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Sdiek1_1925	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Sdiek1_1926	COG0569	domain protein
Sdiek1_1927	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Sdiek1_1928	COG1253	flavin adenine dinucleotide binding
Sdiek1_1929	COG0328	RNA-DNA hybrid ribonuclease activity
Sdiek1_1929	COG0406	alpha-ribazole phosphatase activity
Sdiek1_1930	COG2068	MobA-Related Protein
Sdiek1_1931	COG3608	succinylglutamate desuccinylase aspartoacylase
Sdiek1_1931	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Sdiek1_1933	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Sdiek1_1934	COG0535	radical SAM domain protein
Sdiek1_1940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Sdiek1_1940	COG0784	Response regulator, receiver
Sdiek1_1940	COG2205	protein histidine kinase activity
Sdiek1_1940	COG2198	Histidine kinase
Sdiek1_1942	COG0668	transmembrane transport
Sdiek1_1945	COG4263	nitrous-oxide reductase activity
Sdiek1_1949	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Sdiek1_1951	COG1410	methionine synthase
Sdiek1_1951	COG0646	methionine synthase
Sdiek1_1954	COG0840	transmembrane signaling receptor activity
Sdiek1_1955	COG1280	lysine exporter protein (LysE YggA)
Sdiek1_1956	COG0697	spore germination
Sdiek1_1959	COG0004	ammonium transporteR
Sdiek1_1960	COG0347	Belongs to the P(II) protein family
Sdiek1_1967	COG0288	reversible hydration of carbon dioxide
Sdiek1_1968	COG3123	guanosine phosphorylase activity
Sdiek1_1970	COG2081	HI0933 family
Sdiek1_1972	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Sdiek1_1973	COG0788	formyltetrahydrofolate deformylase activity
Sdiek1_1974	COG0617	tRNA 3'-terminal CCA addition
Sdiek1_1977	COG0473	3-isopropylmalate dehydrogenase activity
Sdiek1_1978	COG0066	3-isopropylmalate dehydratase activity
Sdiek1_1983	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Sdiek1_1985	COG0708	Exodeoxyribonuclease III
Sdiek1_1988	COG2816	NAD+ diphosphatase activity
Sdiek1_1989	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Sdiek1_1990	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
Sdiek1_1994	COG3290	protein histidine kinase activity
Sdiek1_1994	COG0840	transmembrane signaling receptor activity
Sdiek1_1995	COG4977	sequence-specific DNA binding
Sdiek1_1996	COG0431	NADPH-dependent FMN reductase
Sdiek1_1997	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
Sdiek1_1999	COG3706	GGDEF domain
Sdiek1_2001	COG4895	conserved protein (DUF2196)
Sdiek1_2008	COG0513	Belongs to the DEAD box helicase family
Sdiek1_2012	COG0745	RESPONSE REGULATOR receiver
Sdiek1_2019	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Sdiek1_2020	COG0372	Belongs to the citrate synthase family
Sdiek1_2021	COG2079	MmgE PrpD family protein
Sdiek1_2023	COG2824	Alkylphosphonate utilization operon protein PhnA
Sdiek1_2025	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Sdiek1_2027	COG4786	Flagellar basal body rod
Sdiek1_2028	COG4786	Flagellar basal body rod
Sdiek1_2029	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Sdiek1_2031	COG1733	regulation of RNA biosynthetic process
Sdiek1_2034	COG1121	(ABC) transporter
Sdiek1_2035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Sdiek1_2038	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Sdiek1_2039	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Sdiek1_2040	COG3162	membrane
Sdiek1_2041	COG0745	RESPONSE REGULATOR receiver
Sdiek1_2045	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Sdiek1_2046	COG1918	ferrous iron import across plasma membrane
Sdiek1_2051	COG3585	molybdate ion transport
Sdiek1_2053	COG0598	Magnesium transport protein CorA
Sdiek1_2054	COG0739	heme binding
Sdiek1_2056	COG0277	FAD linked oxidase domain protein
Sdiek1_2057	COG1295	ribonuclease BN
Sdiek1_2059	COG0305	Participates in initiation and elongation during chromosome replication
Sdiek1_2060	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Sdiek1_2061	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Sdiek1_2066	COG0556	nucleotide-excision repair
Sdiek1_2069	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Sdiek1_2070	COG2176	DNA-directed DNA polymerase activity
Sdiek1_2071	COG0135	phosphoribosylanthranilate isomerase activity
Sdiek1_2072	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Sdiek1_2074	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Sdiek1_2077	COG1692	metallophosphoesterase
Sdiek1_2078	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Sdiek1_2080	COG0739	heme binding
Sdiek1_2081	COG0285	dihydrofolate synthase activity
Sdiek1_2082	COG3706	GGDEF domain
Sdiek1_2084	COG0495	leucyl-tRNA aminoacylation
Sdiek1_2085	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Sdiek1_2086	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Sdiek1_2087	COG1862	Preprotein translocase
Sdiek1_2088	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Sdiek1_2089	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Sdiek1_2091	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Sdiek1_2093	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Sdiek1_2095	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Sdiek1_2096	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Sdiek1_2097	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Sdiek1_2098	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Sdiek1_2099	COG0210	DNA helicase
Sdiek1_2105	COG0540	Belongs to the ATCase OTCase family
Sdiek1_2107	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Sdiek1_2109	COG3708	Transcriptional regulator
Sdiek1_2109	COG2207	Transcriptional regulator
Sdiek1_2113	COG0336	Belongs to the RNA methyltransferase TrmD family
Sdiek1_2114	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Sdiek1_2115	COG1837	Belongs to the UPF0109 family
Sdiek1_2116	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Sdiek1_2117	COG0564	pseudouridine synthase activity
Sdiek1_2118	COG1519	Transferase
Sdiek1_2120	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Sdiek1_2121	COG0752	glycyl-tRNA synthetase alpha subunit
Sdiek1_2123	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Sdiek1_2126	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Sdiek1_2127	COG0174	glutamine synthetase
Sdiek1_2129	COG4172	Belongs to the ABC transporter superfamily
Sdiek1_2130	COG0156	8-amino-7-oxononanoate synthase activity
Sdiek1_2131	COG0424	maF-like protein
Sdiek1_2133	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Sdiek1_2137	COG1028	Short-chain dehydrogenase reductase Sdr
Sdiek1_2139	COG0673	inositol 2-dehydrogenase activity
Sdiek1_2140	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Sdiek1_2141	COG0768	penicillin binding
Sdiek1_2142	COG1677	Flagellar hook-basal body complex protein FliE
Sdiek1_2143	COG1558	bacterial-type flagellum-dependent cell motility
Sdiek1_2144	COG1815	bacterial-type flagellum-dependent cell motility
Sdiek1_2145	COG0772	Belongs to the SEDS family
Sdiek1_2146	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Sdiek1_2149	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Sdiek1_2161	COG0512	Glutamine amidotransferase of anthranilate synthase
Sdiek1_2162	COG2814	Major facilitator Superfamily
Sdiek1_2163	COG0318	PFAM AMP-dependent synthetase and ligase
Sdiek1_2163	COG0204	Acyl-transferase
Sdiek1_2164	COG0640	Transcriptional regulator
Sdiek1_2166	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
Sdiek1_2168	COG2301	Belongs to the HpcH HpaI aldolase family
Sdiek1_2169	COG3052	prosthetic group binding
Sdiek1_2170	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
Sdiek1_2172	COG2814	Major facilitator Superfamily
Sdiek1_2174	COG2252	PERMEase
Sdiek1_2175	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Sdiek1_2176	COG0133	tryptophan synthase activity
Sdiek1_2178	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Sdiek1_2179	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Sdiek1_2180	COG3706	GGDEF domain
Sdiek1_2184	COG2199	diguanylate cyclase activity
Sdiek1_2184	COG2202	Pas domain
Sdiek1_2184	COG2200	EAL domain
Sdiek1_2186	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Sdiek1_2190	COG0488	(ABC) transporter
Sdiek1_2191	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Sdiek1_2192	COG0651	ATP synthesis coupled electron transport
Sdiek1_2193	COG0650	Formate hydrogenlyase subunit 4
Sdiek1_2194	COG4237	Hydrogenase 4 membrane
Sdiek1_2195	COG0651	ATP synthesis coupled electron transport
Sdiek1_2196	COG0651	ATP synthesis coupled electron transport
Sdiek1_2197	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
Sdiek1_2197	COG3261	NADH dehydrogenase
Sdiek1_2199	COG3260	NADH ubiquinone oxidoreductase 20
Sdiek1_2206	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Sdiek1_2207	COG3706	GGDEF domain
Sdiek1_2207	COG0745	RESPONSE REGULATOR receiver
Sdiek1_2209	COG2171	N-acyltransferase activity
Sdiek1_2210	COG0489	protein tyrosine kinase activity
Sdiek1_2211	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Sdiek1_2211	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Sdiek1_2214	COG2046	Belongs to the sulfate adenylyltransferase family
Sdiek1_2216	COG2353	YceI-like domain
Sdiek1_2217	COG1739	Uncharacterized protein family UPF0029
Sdiek1_2218	COG0157	Belongs to the NadC ModD family
Sdiek1_2219	COG4149	molybdate abc transporter
Sdiek1_2221	COG3842	ATPase activity
Sdiek1_2226	COG1686	Belongs to the peptidase S11 family
Sdiek1_2227	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Sdiek1_2228	COG1136	(ABC) transporter
Sdiek1_2228	COG0577	efflux transmembrane transporter activity
Sdiek1_2229	COG1136	(ABC) transporter
Sdiek1_2234	COG0668	transmembrane transport
Sdiek1_2236	COG5001	Diguanylate cyclase
Sdiek1_2236	COG3300	MHYT domain
Sdiek1_2256	COG1450	Type ii and iii secretion system protein
Sdiek1_2269	COG0284	orotidine-5'-phosphate decarboxylase activity
Sdiek1_2270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Sdiek1_2273	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Sdiek1_2274	COG0697	spore germination
Sdiek1_2275	COG0668	transmembrane transport
Sdiek1_2276	COG1160	GTP binding
Sdiek1_2278	COG0180	Tryptophanyl-tRNA synthetase
Sdiek1_2279	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Sdiek1_2281	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Sdiek1_2282	COG1183	phosphatidylcholine synthase activity
Sdiek1_2284	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Sdiek1_2285	COG2264	protein methyltransferase activity
Sdiek1_2287	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Sdiek1_2288	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Sdiek1_2291	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Sdiek1_2299	COG0028	Belongs to the TPP enzyme family
Sdiek1_2301	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Sdiek1_2304	COG1793	dna ligase
Sdiek1_2306	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Sdiek1_2307	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Sdiek1_2310	COG0859	PFAM glycosyl transferase family 9
Sdiek1_2314	COG0859	PFAM glycosyl transferase family 9
Sdiek1_2316	COG1215	transferase activity, transferring glycosyl groups
Sdiek1_2319	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Sdiek1_2320	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Sdiek1_2320	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Sdiek1_2322	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Sdiek1_2326	COG2217	Heavy metal translocating P-type atpase
Sdiek1_2328	COG5001	Diguanylate cyclase
Sdiek1_2328	COG5002	protein histidine kinase activity
Sdiek1_2329	COG0697	spore germination
Sdiek1_2332	COG3706	GGDEF domain
Sdiek1_2337	COG0840	transmembrane signaling receptor activity
Sdiek1_2338	COG1984	allophanate hydrolase subunit 2
Sdiek1_2340	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Sdiek1_2341	COG0445	tRNA wobble uridine modification
Sdiek1_2342	COG0723	plastoquinol--plastocyanin reductase activity
Sdiek1_2343	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Sdiek1_2344	COG2857	Cytochrome c1
Sdiek1_2346	COG0825	malonyl-CoA metabolic process
Sdiek1_2347	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Sdiek1_2348	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Sdiek1_2350	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Sdiek1_2351	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Sdiek1_2352	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Sdiek1_2354	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Sdiek1_2356	COG0297	glycogen (starch) synthase activity
Sdiek1_2358	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Sdiek1_2359	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Sdiek1_2362	COG1215	transferase activity, transferring glycosyl groups
Sdiek1_2369	COG0572	uridine kinase
Sdiek1_2378	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
Sdiek1_2378	COG0662	Cupin 2, conserved barrel domain protein
Sdiek1_2379	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Sdiek1_2385	COG0745	RESPONSE REGULATOR receiver
Sdiek1_2388	COG0398	Pfam SNARE associated Golgi protein
Sdiek1_2389	COG4943	cyclic-guanylate-specific phosphodiesterase activity
Sdiek1_2393	COG0390	transport system, permease component
Sdiek1_2394	COG0439	Biotin carboxylase
Sdiek1_2397	COG0513	Belongs to the DEAD box helicase family
Sdiek1_2398	COG1671	Belongs to the UPF0178 family
Sdiek1_2399	COG0667	Aldo Keto reductase
Sdiek1_2400	COG2814	Major facilitator Superfamily
Sdiek1_2401	COG2207	Transcriptional regulator
Sdiek1_2405	COG0573	inorganic phosphate transmembrane transporter activity
Sdiek1_2407	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Sdiek1_2408	COG3290	protein histidine kinase activity
Sdiek1_2408	COG0840	transmembrane signaling receptor activity
Sdiek1_2409	COG3384	dioxygenase
Sdiek1_2410	COG0840	transmembrane signaling receptor activity
Sdiek1_2413	COG0745	RESPONSE REGULATOR receiver
Sdiek1_2415	COG1607	acyl-coa hydrolase
Sdiek1_2420	COG1733	regulation of RNA biosynthetic process
Sdiek1_2421	COG2249	NAD(P)H dehydrogenase (quinone) activity
Sdiek1_2422	COG3852	Histidine kinase
Sdiek1_2423	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Sdiek1_2424	COG0602	queuosine metabolic process
Sdiek1_2431	COG1702	phosphate starvation-inducible protein PhoH
Sdiek1_2433	COG2814	Major facilitator Superfamily
Sdiek1_2434	COG0477	Major facilitator Superfamily
Sdiek1_2435	COG1538	Outer membrane efflux protein
Sdiek1_2436	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Sdiek1_2440	COG3787	Belongs to the UPF0306 family
Sdiek1_2441	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
Sdiek1_2447	COG1013	pyruvate-flavodoxin oxidoreductase activity
Sdiek1_2447	COG0674	pyruvate-flavodoxin oxidoreductase activity
Sdiek1_2447	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Sdiek1_2447	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Sdiek1_2449	COG0471	metal ion transport
Sdiek1_2451	COG0668	transmembrane transport
Sdiek1_2452	COG3047	cAMP biosynthetic process
Sdiek1_2452	COG2885	chlorophyll binding
Sdiek1_2454	COG1881	PFAM PEBP family protein
Sdiek1_2455	COG2207	Transcriptional regulator
Sdiek1_2456	COG0519	Catalyzes the synthesis of GMP from XMP
Sdiek1_2460	COG1979	alcohol dehydrogenase
Sdiek1_2463	COG0038	chloride channel
Sdiek1_2464	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Sdiek1_2466	COG0500	methyltransferase
Sdiek1_2468	COG1324	tolerance protein
Sdiek1_2470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Sdiek1_2479	COG3278	Belongs to the heme-copper respiratory oxidase family
Sdiek1_2480	COG0745	RESPONSE REGULATOR receiver
Sdiek1_2485	COG0505	Belongs to the CarA family
Sdiek1_2489	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Sdiek1_2490	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Sdiek1_2491	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Sdiek1_2493	COG0546	phosphoglycolate phosphatase activity
Sdiek1_2498	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Sdiek1_2499	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Sdiek1_2500	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Sdiek1_2503	COG0203	ribosomal protein L17
Sdiek1_2505	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Sdiek1_2506	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Sdiek1_2507	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Sdiek1_2509	COG0024	Methionine aminopeptidase
Sdiek1_2510	COG0201	protein transport
Sdiek1_2511	COG0200	Binds to the 23S rRNA
Sdiek1_2513	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Sdiek1_2514	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Sdiek1_2515	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Sdiek1_2517	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Sdiek1_2518	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Sdiek1_2519	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Sdiek1_2520	COG0255	Belongs to the universal ribosomal protein uL29 family
Sdiek1_2521	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Sdiek1_2522	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Sdiek1_2524	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Sdiek1_2525	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Sdiek1_2526	COG0089	rRNA binding
Sdiek1_2527	COG0088	Forms part of the polypeptide exit tunnel
Sdiek1_2528	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Sdiek1_2529	COG0051	transcription antitermination factor activity, RNA binding
Sdiek1_2533	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Sdiek1_2535	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Sdiek1_2536	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Sdiek1_2537	COG0571	ribonuclease III activity
Sdiek1_2538	COG0328	RNA-DNA hybrid ribonuclease activity
Sdiek1_2540	COG0358	DNA primase activity
Sdiek1_2541	COG0137	argininosuccinate synthase activity
Sdiek1_2542	COG2201	protein-glutamate methylesterase activity
Sdiek1_2545	COG0745	RESPONSE REGULATOR receiver
Sdiek1_2546	COG2205	protein histidine kinase activity
Sdiek1_2547	COG2201	protein-glutamate methylesterase activity
Sdiek1_2548	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Sdiek1_2549	COG5002	protein histidine kinase activity
Sdiek1_2551	COG2198	Histidine kinase
Sdiek1_2551	COG0643	Histidine kinase
Sdiek1_2553	COG0840	transmembrane signaling receptor activity
Sdiek1_2554	COG0835	chemotaxis
Sdiek1_2557	COG0484	heat shock protein binding
Sdiek1_2562	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
Sdiek1_2563	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
Sdiek1_2568	COG1280	lysine exporter protein (LysE YggA)
Sdiek1_2569	COG1090	epimerase
Sdiek1_2571	COG1136	(ABC) transporter
Sdiek1_2577	COG2962	Rard protein
Sdiek1_2578	COG0745	RESPONSE REGULATOR receiver
Sdiek1_2579	COG5002	protein histidine kinase activity
Sdiek1_2580	COG2194	sulfuric ester hydrolase activity
Sdiek1_2582	COG2200	EAL domain
Sdiek1_2585	COG1968	undecaprenyl-diphosphatase activity
Sdiek1_2586	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Sdiek1_2587	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
Sdiek1_2591	COG1027	Aspartate ammonia-lyase
Sdiek1_2592	COG1027	Aspartate ammonia-lyase
Sdiek1_2593	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Sdiek1_2594	COG0252	asparaginase activity
Sdiek1_2595	COG4191	Histidine kinase
Sdiek1_2596	COG0745	RESPONSE REGULATOR receiver
Sdiek1_2598	COG0714	Associated with various cellular activities
Sdiek1_2610	COG0765	amino acid transport
Sdiek1_2624	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Sdiek1_2632	COG0709	Synthesizes selenophosphate from selenide and ATP
Sdiek1_2633	COG0425	Belongs to the sulfur carrier protein TusA family
Sdiek1_2635	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Sdiek1_2637	COG3447	MASE1 domain protein
Sdiek1_2637	COG5001	Diguanylate cyclase
Sdiek1_2637	COG5002	protein histidine kinase activity
Sdiek1_2639	COG2814	Major facilitator Superfamily
Sdiek1_2643	COG3839	Belongs to the ABC transporter superfamily
Sdiek1_2644	COG4662	Binding-protein-dependent transport system inner membrane component
Sdiek1_2645	COG2998	abc-type tungstate transport system, permease component
Sdiek1_2647	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Sdiek1_2649	COG0437	4 iron, 4 sulfur cluster binding
Sdiek1_2654	COG0437	4 iron, 4 sulfur cluster binding
Sdiek1_2655	COG0243	molybdopterin cofactor binding
Sdiek1_2655	COG3383	formate dehydrogenase (NAD+) activity
Sdiek1_2658	COG1120	ATPase activity
Sdiek1_2661	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Sdiek1_2664	COG0848	biopolymer transport protein
Sdiek1_2665	COG0811	peptide transport
Sdiek1_2670	COG0500	methyltransferase
Sdiek1_2672	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Sdiek1_2673	COG4208	sulfate ABC transporter
Sdiek1_2674	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Sdiek1_2675	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Sdiek1_2676	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Sdiek1_2685	COG0437	4 iron, 4 sulfur cluster binding
Sdiek1_2691	COG2205	protein histidine kinase activity
Sdiek1_2693	COG1921	L-seryl-tRNASec selenium transferase activity
Sdiek1_2698	COG1741	Belongs to the pirin family
Sdiek1_2705	COG0745	RESPONSE REGULATOR receiver
Sdiek1_2706	COG5002	protein histidine kinase activity
Sdiek1_2706	COG5000	phosphorelay sensor kinase activity
Sdiek1_2710	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Sdiek1_2711	COG0463	Glycosyl transferase, family 2
Sdiek1_2713	COG1028	Short-chain dehydrogenase reductase Sdr
Sdiek1_2717	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Sdiek1_2722	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Sdiek1_2724	COG0513	Belongs to the DEAD box helicase family
Sdiek1_2730	COG1305	Transglutaminase-like
Sdiek1_2738	COG0439	Biotin carboxylase
Sdiek1_2741	COG3842	ATPase activity
Sdiek1_2742	COG2011	ABC-type metal ion transport system permease component
Sdiek1_2747	COG0745	RESPONSE REGULATOR receiver
Sdiek1_2748	COG2205	protein histidine kinase activity
Sdiek1_2749	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
Sdiek1_2750	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
Sdiek1_2751	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Sdiek1_2753	COG0840	transmembrane signaling receptor activity
Sdiek1_2754	COG0300	oxidoreductase activity
Sdiek1_2757	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Sdiek1_2759	COG2814	Major facilitator Superfamily
Sdiek1_2760	COG1238	metal cluster binding
Sdiek1_2763	COG0471	metal ion transport
Sdiek1_2766	COG0303	'Molybdopterin
Sdiek1_2767	COG0314	molybdopterin synthase activity
Sdiek1_2771	COG1157	protein secretion by the type III secretion system
Sdiek1_2772	COG0302	gtp cyclohydrolase
Sdiek1_2773	COG0544	peptidyl-prolyl cis-trans isomerase activity
Sdiek1_2774	COG0740	serine-type endopeptidase activity
Sdiek1_2777	COG0606	chelatase, subunit chli
Sdiek1_2778	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Sdiek1_2778	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Sdiek1_2780	COG2022	thiamine diphosphate biosynthetic process
Sdiek1_2790	COG0745	RESPONSE REGULATOR receiver
Sdiek1_2791	COG2205	protein histidine kinase activity
Sdiek1_2793	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Sdiek1_2794	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Sdiek1_2797	COG0463	Glycosyl transferase, family 2
Sdiek1_2803	COG1012	belongs to the aldehyde dehydrogenase family
Sdiek1_2806	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Sdiek1_2810	COG0840	transmembrane signaling receptor activity
Sdiek1_2811	COG2183	response to ionizing radiation
Sdiek1_2812	COG3300	MHYT domain
Sdiek1_2812	COG5001	Diguanylate cyclase
Sdiek1_2817	COG0842	Transport permease protein
Sdiek1_2818	COG0842	Transport permease protein
Sdiek1_2819	COG1131	(ABC) transporter
Sdiek1_2820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Sdiek1_2821	COG1309	transcriptional regulator
Sdiek1_2822	COG0778	Nitroreductase
Sdiek1_2830	COG1136	(ABC) transporter
Sdiek1_2835	COG1472	Belongs to the glycosyl hydrolase 3 family
Sdiek1_2840	COG0454	-acetyltransferase
Sdiek1_2841	COG0431	NADPH-dependent FMN reductase
Sdiek1_2843	COG4221	oxidoreductase activity
Sdiek1_2844	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Sdiek1_2845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Sdiek1_2853	COG0745	RESPONSE REGULATOR receiver
Sdiek1_2854	COG0642	Histidine kinase
Sdiek1_2856	COG1178	ABC-type Fe3 transport system permease component
Sdiek1_2858	COG1840	ABC-type Fe3 transport system, periplasmic component
Sdiek1_2860	COG0175	sulfate reduction
Sdiek1_2861	COG0175	sulfate reduction
Sdiek1_2862	COG2895	sulfate adenylyltransferase (ATP) activity
Sdiek1_2864	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Sdiek1_2866	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Sdiek1_2867	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Sdiek1_2867	COG1648	precorrin-2 dehydrogenase activity
Sdiek1_2868	COG2873	o-acetylhomoserine
Sdiek1_2870	COG0482	sulfurtransferase activity
Sdiek1_2874	COG3706	GGDEF domain
Sdiek1_2876	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Sdiek1_2878	COG0861	Integral membrane protein TerC family
Sdiek1_2879	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Sdiek1_2880	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Sdiek1_2881	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Sdiek1_2882	COG0281	malic enzyme
Sdiek1_2882	COG0280	phosphate acetyltransferase
Sdiek1_2883	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Sdiek1_2885	COG0439	Biotin carboxylase
Sdiek1_2886	COG0511	ligase activity, forming carbon-carbon bonds
Sdiek1_2887	COG0717	Belongs to the dCTP deaminase family
Sdiek1_2892	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Sdiek1_2893	COG1073	alpha beta
Sdiek1_2896	COG1086	Polysaccharide biosynthesis protein
Sdiek1_2897	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Sdiek1_2898	COG1083	cytidylyl-transferase
Sdiek1_2900	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Sdiek1_2901	COG2089	acid synthase
Sdiek1_2904	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Sdiek1_2905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Sdiek1_2907	COG0154	amidase activity
Sdiek1_2911	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Sdiek1_2912	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Sdiek1_2913	COG0372	Belongs to the citrate synthase family
Sdiek1_2917	COG0148	phosphopyruvate hydratase activity
Sdiek1_2918	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Sdiek1_2919	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Sdiek1_2921	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Sdiek1_2924	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Sdiek1_2930	COG1408	metallophosphoesterase
Sdiek1_2931	COG1115	amino acid carrier protein
Sdiek1_2932	COG2233	PERMEase
Sdiek1_2933	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Sdiek1_2934	COG0575	Belongs to the CDS family
Sdiek1_2937	COG1929	Belongs to the glycerate kinase type-1 family
Sdiek1_2938	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Sdiek1_2941	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Sdiek1_2943	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Sdiek1_2944	COG0746	molybdenum cofactor guanylyltransferase activity
Sdiek1_2950	COG0724	RNA recognition motif
Sdiek1_2951	COG0315	cyclic pyranopterin monophosphate synthase activity
Sdiek1_2952	COG2921	Belongs to the UPF0250 family
Sdiek1_2969	COG0670	Belongs to the BI1 family
Sdiek1_2980	COG0437	4 iron, 4 sulfur cluster binding
Sdiek1_2981	COG0243	molybdopterin cofactor binding
Sdiek1_2982	COG4106	trans-aconitate 2-methyltransferase activity
Sdiek1_2986	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Sdiek1_2987	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Sdiek1_2989	COG0233	cytoplasmic translational termination
Sdiek1_2990	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Sdiek1_2995	COG1704	LemA family
Sdiek1_2998	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Sdiek1_2999	COG1749	Flagellar hook protein flgE
Sdiek1_3000	COG1749	Flagellar hook protein flgE
Sdiek1_3001	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
Sdiek1_3002	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group