locus-tag	class	description
SUN_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SUN_0002	COG0592	DNA-directed DNA polymerase activity
SUN_0003	COG0504	CTP synthase activity
SUN_0004	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SUN_0004	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SUN_0006	COG0822	iron-sulfur transferase activity
SUN_0006	COG2906	2 iron, 2 sulfur cluster binding
SUN_0006	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SUN_0010	COG1194	a g-specific adenine glycosylase
SUN_0011	COG0544	peptidyl-prolyl cis-trans isomerase activity
SUN_0012	COG0740	serine-type endopeptidase activity
SUN_0013	COG0242	peptide deformylase activity
SUN_0014	COG0606	chelatase, subunit chli
SUN_0015	COG2855	membrane
SUN_0016	COG0583	DNA-binding transcription factor activity
SUN_0017	COG0746	molybdenum cofactor guanylyltransferase activity
SUN_0021	COG1459	type II secretion system
SUN_0034	COG0784	Response regulator, receiver
SUN_0034	COG4191	Histidine kinase
SUN_0035	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SUN_0036	COG0233	cytoplasmic translational termination
SUN_0037	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SUN_0039	COG0670	Belongs to the BI1 family
SUN_0041	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SUN_0042	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SUN_0043	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SUN_0063	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SUN_0064	COG0268	Binds directly to 16S ribosomal RNA
SUN_0065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SUN_0066	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SUN_0070	COG0315	cyclic pyranopterin monophosphate synthase activity
SUN_0072	COG0348	domain, Protein
SUN_0075	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SUN_0080	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SUN_0081	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SUN_0082	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SUN_0083	COG0148	phosphopyruvate hydratase activity
SUN_0086	COG0569	domain protein
SUN_0086	COG0475	glutathione-regulated potassium exporter activity
SUN_0087	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SUN_0088	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SUN_0090	COG0717	Belongs to the dCTP deaminase family
SUN_0091	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SUN_0098	COG0438	transferase activity, transferring glycosyl groups
SUN_0100	COG0438	transferase activity, transferring glycosyl groups
SUN_0104	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SUN_0105	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SUN_0106	COG1086	Polysaccharide biosynthesis protein
SUN_0108	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SUN_0109	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SUN_0111	COG0314	molybdopterin synthase activity
SUN_0112	COG0303	'Molybdopterin
SUN_0115	COG1331	Highly conserved protein containing a thioredoxin domain
SUN_0117	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SUN_0118	COG0023	Translation Initiation Factor
SUN_0120	COG1028	Short-chain dehydrogenase reductase Sdr
SUN_0120	COG3347	Dehydrogenase
SUN_0122	COG3022	response to hydroperoxide
SUN_0123	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SUN_0124	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SUN_0126	COG0250	Participates in transcription elongation, termination and antitermination
SUN_0127	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SUN_0128	COG0081	regulation of translation
SUN_0129	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SUN_0130	COG0222	ribosome binding
SUN_0131	COG0085	RNA polymerase activity
SUN_0132	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SUN_0133	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SUN_0134	COG0049	tRNA binding
SUN_0135	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SUN_0139	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SUN_0140	COG2199	diguanylate cyclase activity
SUN_0140	COG2200	EAL domain
SUN_0141	COG0187	DNA topoisomerase II activity
SUN_0142	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SUN_0144	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SUN_0145	COG0575	Belongs to the CDS family
SUN_0147	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SUN_0152	COG1053	succinate dehydrogenase
SUN_0153	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SUN_0154	COG0432	Pfam Uncharacterised protein family UPF0047
SUN_0155	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SUN_0156	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SUN_0157	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SUN_0157	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SUN_0159	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SUN_0162	COG0534	Mate efflux family protein
SUN_0164	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SUN_0166	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SUN_0167	COG2814	Major facilitator Superfamily
SUN_0168	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SUN_0171	COG1473	amidohydrolase
SUN_0172	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SUN_0173	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SUN_0174	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SUN_0176	COG0505	Belongs to the CarA family
SUN_0177	COG1181	Belongs to the D-alanine--D-alanine ligase family
SUN_0178	COG3278	Belongs to the heme-copper respiratory oxidase family
SUN_0187	COG1074	ATP-dependent DNA helicase activity
SUN_0188	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SUN_0189	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SUN_0190	COG0242	peptide deformylase activity
SUN_0195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SUN_0198	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SUN_0199	COG1144	Oxidoreductase
SUN_0200	COG0674	pyruvate-flavodoxin oxidoreductase activity
SUN_0201	COG1013	pyruvate-flavodoxin oxidoreductase activity
SUN_0202	COG1854	S-ribosylhomocysteine lyase activity
SUN_0206	COG0445	tRNA wobble uridine modification
SUN_0210	COG2857	Cytochrome c1
SUN_0211	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SUN_0212	COG0602	queuosine metabolic process
SUN_0215	COG0720	synthase
SUN_0216	COG0303	'Molybdopterin
SUN_0218	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SUN_0220	COG0254	rRNA binding
SUN_0221	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SUN_0222	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SUN_0224	COG0436	Aminotransferase
SUN_0225	COG0460	homoserine dehydrogenase
SUN_0226	COG1666	GTP binding
SUN_0228	COG3383	formate dehydrogenase (NAD+) activity
SUN_0231	COG0792	nuclease activity
SUN_0233	COG3118	belongs to the thioredoxin family
SUN_0234	COG0492	ferredoxin-NADP+ reductase activity
SUN_0235	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SUN_0236	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SUN_0237	COG0140	phosphoribosyl-ATP diphosphatase activity
SUN_0237	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SUN_0244	COG3256	nitric oxide reductase
SUN_0247	COG0569	domain protein
SUN_0248	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SUN_0251	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SUN_0253	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SUN_0259	COG0651	ATP synthesis coupled electron transport
SUN_0262	COG0651	ATP synthesis coupled electron transport
SUN_0263	COG0649	NAD binding
SUN_0263	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SUN_0263	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SUN_0264	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SUN_0265	COG0038	chloride channel
SUN_0266	COG0300	oxidoreductase activity
SUN_0268	COG2010	Cytochrome c
SUN_0269	COG0300	oxidoreductase activity
SUN_0270	COG1858	cytochrome C peroxidase
SUN_0272	COG1309	transcriptional regulator
SUN_0279	COG0842	Transport permease protein
SUN_0279	COG1129	ABC transporter
SUN_0280	COG0842	Transport permease protein
SUN_0281	COG0842	Transport permease protein
SUN_0282	COG1196	nuclear chromosome segregation
SUN_0282	COG3264	Mechanosensitive ion channel
SUN_0284	COG0671	phosphoesterase, PA-phosphatase related
SUN_0293	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SUN_0295	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SUN_0295	COG1648	precorrin-2 dehydrogenase activity
SUN_0298	COG2151	metal-sulfur cluster biosynthetic enzyme
SUN_0299	COG0243	molybdopterin cofactor binding
SUN_0300	COG0437	4 iron, 4 sulfur cluster binding
SUN_0301	COG0348	domain, Protein
SUN_0302	COG3043	anaerobic respiration
SUN_0308	COG1012	belongs to the aldehyde dehydrogenase family
SUN_0313	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SUN_0314	COG0052	Belongs to the universal ribosomal protein uS2 family
SUN_0315	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SUN_0316	COG1136	(ABC) transporter
SUN_0317	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SUN_0318	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SUN_0319	COG0768	penicillin binding
SUN_0320	COG0772	Belongs to the SEDS family
SUN_0321	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SUN_0324	COG0662	Cupin 2, conserved barrel domain protein
SUN_0324	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SUN_0327	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SUN_0329	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SUN_0332	COG0277	FAD linked oxidase domain protein
SUN_0336	COG0457	Tetratricopeptide repeat
SUN_0337	COG0457	Tetratricopeptide repeat
SUN_0342	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SUN_0343	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SUN_0345	COG0438	transferase activity, transferring glycosyl groups
SUN_0346	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SUN_0348	COG0424	maF-like protein
SUN_0349	COG0156	8-amino-7-oxononanoate synthase activity
SUN_0353	COG0174	glutamine synthetase
SUN_0354	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SUN_0356	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SUN_0359	COG0752	glycyl-tRNA synthetase alpha subunit
SUN_0360	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SUN_0362	COG1519	Transferase
SUN_0364	COG1872	DUF167
SUN_0365	COG0564	pseudouridine synthase activity
SUN_0366	COG2989	Protein conserved in bacteria
SUN_0367	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SUN_0368	COG0228	four-way junction DNA binding
SUN_0369	COG1837	Belongs to the UPF0109 family
SUN_0370	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SUN_0371	COG0336	Belongs to the RNA methyltransferase TrmD family
SUN_0372	COG0335	large ribosomal subunit rRNA binding
SUN_0375	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SUN_0376	COG4628	conserved protein (DUF2132)
SUN_0379	COG0071	Belongs to the small heat shock protein (HSP20) family
SUN_0381	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SUN_0383	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SUN_0385	COG0583	DNA-binding transcription factor activity
SUN_0387	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SUN_0391	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SUN_0392	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SUN_0393	COG1862	Preprotein translocase
SUN_0394	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SUN_0395	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SUN_0398	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SUN_0399	COG2027	D-alanyl-D-alanine carboxypeptidase
SUN_0411	COG0563	adenylate kinase activity
SUN_0413	COG1053	succinate dehydrogenase
SUN_0414	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SUN_0416	COG1193	negative regulation of DNA recombination
SUN_0423	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SUN_0424	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SUN_0426	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SUN_0427	COG0629	single-stranded DNA binding
SUN_0428	COG0360	Binds together with S18 to 16S ribosomal RNA
SUN_0430	COG1466	dna polymerase III delta subunit
SUN_0431	COG0557	exoribonuclease II activity
SUN_0432	COG0579	oxidoreductase
SUN_0433	COG0501	Belongs to the peptidase M48B family
SUN_0438	COG1592	Rubrerythrin
SUN_0443	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SUN_0445	COG0758	DNA mediated transformation
SUN_0446	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SUN_0447	COG1472	Belongs to the glycosyl hydrolase 3 family
SUN_0448	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SUN_0449	COG0791	NLP P60 protein
SUN_0451	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SUN_0452	COG0805	protein transport
SUN_0453	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SUN_0454	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SUN_0455	COG0494	nUDIX hydrolase
SUN_0456	COG0527	aspartate kinase activity
SUN_0459	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SUN_0460	COG2949	membrane
SUN_0461	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SUN_0465	COG2226	methyltransferase
SUN_0466	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SUN_0467	COG2205	protein histidine kinase activity
SUN_0470	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SUN_0471	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SUN_0477	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SUN_0480	COG0475	glutathione-regulated potassium exporter activity
SUN_0481	COG2951	lytic endotransglycosylase activity
SUN_0482	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SUN_0486	COG1393	Belongs to the ArsC family
SUN_0487	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SUN_0489	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SUN_0495	COG0745	RESPONSE REGULATOR receiver
SUN_0496	COG5002	protein histidine kinase activity
SUN_0501	COG0737	Belongs to the 5'-nucleotidase family
SUN_0504	COG1331	Highly conserved protein containing a thioredoxin domain
SUN_0515	COG0280	phosphate acetyltransferase
SUN_0515	COG0281	malic enzyme
SUN_0517	COG1160	GTP binding
SUN_0519	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
SUN_0520	COG2046	Belongs to the sulfate adenylyltransferase family
SUN_0521	COG0745	RESPONSE REGULATOR receiver
SUN_0522	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SUN_0522	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SUN_0523	COG0489	protein tyrosine kinase activity
SUN_0525	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SUN_0526	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SUN_0529	COG2022	thiamine diphosphate biosynthetic process
SUN_0531	COG0351	phosphomethylpyrimidine kinase
SUN_0536	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SUN_0537	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SUN_0538	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SUN_0539	COG0512	Glutamine amidotransferase of anthranilate synthase
SUN_0543	COG1785	Belongs to the alkaline phosphatase family
SUN_0544	COG0165	Argininosuccinate lyase
SUN_0545	COG0537	adenosine 5'-monophosphoramidase activity
SUN_0546	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SUN_0547	COG0072	phenylalanine-tRNA ligase activity
SUN_0547	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SUN_0548	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SUN_0549	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SUN_0550	COG1185	polyribonucleotide nucleotidyltransferase activity
SUN_0550	COG0539	negative regulation of cytoplasmic translation
SUN_0551	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SUN_0555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SUN_0556	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SUN_0563	COG0492	ferredoxin-NADP+ reductase activity
SUN_0564	COG0693	protein deglycase activity
SUN_0567	COG0587	DNA-directed DNA polymerase activity
SUN_0571	COG0039	L-malate dehydrogenase activity
SUN_0572	COG0039	L-malate dehydrogenase activity
SUN_0575	COG0114	fumarate hydratase activity
SUN_0576	COG0045	succinate-CoA ligase (ADP-forming) activity
SUN_0577	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SUN_0579	COG0674	pyruvate-flavodoxin oxidoreductase activity
SUN_0579	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SUN_0580	COG1013	pyruvate-flavodoxin oxidoreductase activity
SUN_0587	COG0243	molybdopterin cofactor binding
SUN_0589	COG0628	permease
SUN_0591	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SUN_0595	COG0736	holo-[acyl-carrier-protein] synthase activity
SUN_0596	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SUN_0597	COG0552	protein localization to endoplasmic reticulum
SUN_0598	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SUN_0600	COG1418	mRNA catabolic process
SUN_0603	COG0500	methyltransferase
SUN_0605	COG0501	Belongs to the peptidase M48B family
SUN_0610	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SUN_0613	COG0754	glutathionylspermidine amidase activity
SUN_0616	COG0849	cell division
SUN_0618	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SUN_0621	COG0784	Response regulator, receiver
SUN_0621	COG2198	Histidine kinase
SUN_0621	COG5002	protein histidine kinase activity
SUN_0623	COG2205	protein histidine kinase activity
SUN_0623	COG0784	Response regulator, receiver
SUN_0623	COG5002	protein histidine kinase activity
SUN_0628	COG4191	Histidine kinase
SUN_0629	COG2197	response regulator
SUN_0630	COG3437	response regulator, receiver
SUN_0632	COG0275	rRNA processing
SUN_0634	COG0181	hydroxymethylbilane synthase activity
SUN_0637	COG0442	prolyl-tRNA aminoacylation
SUN_0638	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SUN_0639	COG0142	geranyltranstransferase activity
SUN_0642	COG0560	Phosphoserine phosphatase
SUN_0643	COG0500	methyltransferase
SUN_0644	COG0708	Exodeoxyribonuclease III
SUN_0648	COG0012	GTP binding
SUN_0651	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SUN_0653	COG0133	tryptophan synthase activity
SUN_0655	COG1408	metallophosphoesterase
SUN_0658	COG0681	Belongs to the peptidase S26 family
SUN_0659	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SUN_0660	COG2205	protein histidine kinase activity
SUN_0662	COG0698	ribose 5-phosphate isomerase
SUN_0663	COG1994	Peptidase M50
SUN_0664	COG0681	Belongs to the peptidase S26 family
SUN_0665	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SUN_0668	COG1278	Cold shock
SUN_0673	COG1272	protein, Hemolysin III
SUN_0674	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SUN_0674	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SUN_0675	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SUN_0676	COG0284	orotidine-5'-phosphate decarboxylase activity
SUN_0678	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SUN_0679	COG3118	belongs to the thioredoxin family
SUN_0680	COG0745	RESPONSE REGULATOR receiver
SUN_0681	COG5002	protein histidine kinase activity
SUN_0685	COG2010	Cytochrome c
SUN_0687	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SUN_0692	COG1331	Highly conserved protein containing a thioredoxin domain
SUN_0695	COG1881	PFAM PEBP family protein
SUN_0702	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
SUN_0704	COG2944	sequence-specific DNA binding
SUN_0711	COG2239	Acts as a magnesium transporter
SUN_0712	COG4536	flavin adenine dinucleotide binding
SUN_0713	COG0513	Belongs to the DEAD box helicase family
SUN_0714	COG3021	interspecies interaction between organisms
SUN_0717	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SUN_0719	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SUN_0722	COG2183	response to ionizing radiation
SUN_0726	COG0419	ATPase involved in DNA repair
SUN_0745	COG1187	pseudouridine synthase activity
SUN_0749	COG3328	transposase activity
SUN_0751	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SUN_0752	COG0450	alkyl hydroperoxide reductase
SUN_0753	COG0735	belongs to the Fur family
SUN_0755	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SUN_0756	COG0750	zinc metalloprotease
SUN_0761	COG0803	Belongs to the bacterial solute-binding protein 9 family
SUN_0762	COG3746	phosphate-selective porin O and P
SUN_0765	COG2132	Multicopper oxidase
SUN_0767	COG2205	protein histidine kinase activity
SUN_0776	COG4232	protein-disulfide reductase activity
SUN_0780	COG5002	protein histidine kinase activity
SUN_0781	COG0745	RESPONSE REGULATOR receiver
SUN_0786	COG0640	Transcriptional regulator
SUN_0787	COG0642	Histidine kinase
SUN_0788	COG0745	RESPONSE REGULATOR receiver
SUN_0792	COG2132	Multicopper oxidase
SUN_0793	COG2226	methyltransferase
SUN_0801	COG2132	Multicopper oxidase
SUN_0805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SUN_0807	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SUN_0808	COG1028	Short-chain dehydrogenase reductase Sdr
SUN_0809	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SUN_0810	COG0612	Peptidase, M16
SUN_0811	COG0167	dihydroorotate dehydrogenase activity
SUN_0820	COG0215	cysteine-tRNA ligase activity
SUN_0821	COG0728	peptidoglycan biosynthetic process
SUN_0823	COG0632	four-way junction helicase activity
SUN_0824	COG4574	serine-type endopeptidase inhibitor activity
SUN_0826	COG0791	NLP P60 protein
SUN_0828	COG2081	HI0933 family
SUN_0829	COG2989	Protein conserved in bacteria
SUN_0830	COG3034	peptidoglycan biosynthetic process
SUN_0832	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SUN_0838	COG2203	Gaf domain
SUN_0838	COG2199	diguanylate cyclase activity
SUN_0840	COG1597	lipid kinase activity
SUN_0842	COG0628	permease
SUN_0845	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SUN_0846	COG0649	NAD binding
SUN_0848	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SUN_0851	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SUN_0852	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SUN_0854	COG0446	pyridine nucleotide-disulphide oxidoreductase
SUN_0855	COG3118	belongs to the thioredoxin family
SUN_0856	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SUN_0857	COG2252	PERMEase
SUN_0858	COG0745	RESPONSE REGULATOR receiver
SUN_0858	COG3706	GGDEF domain
SUN_0864	COG0671	phosphoesterase, PA-phosphatase related
SUN_0870	COG3527	Alpha-acetolactate decarboxylase
SUN_0873	COG3328	transposase activity
SUN_0875	COG0318	PFAM AMP-dependent synthetase and ligase
SUN_0876	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SUN_0883	COG1945	arginine decarboxylase activity
SUN_0884	COG1073	alpha beta
SUN_0887	COG0688	phosphatidylethanolamine metabolic process
SUN_0891	COG0747	negative chemotaxis
SUN_0894	COG0444	Belongs to the ABC transporter superfamily
SUN_0895	COG4608	Belongs to the ABC transporter superfamily
SUN_0897	COG0714	Associated with various cellular activities
SUN_0900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SUN_0903	COG0569	domain protein
SUN_0903	COG2985	domain, Protein
SUN_0904	COG2824	Alkylphosphonate utilization operon protein PhnA
SUN_0907	COG0069	glutamate synthase activity
SUN_0907	COG0070	glutamate synthase
SUN_0907	COG0067	glutamate synthase
SUN_0909	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SUN_0913	COG1643	Atp-dependent helicase
SUN_0915	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SUN_0917	COG2020	methyltransferase activity
SUN_0921	COG0778	Nitroreductase
SUN_0922	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SUN_0928	COG4106	trans-aconitate 2-methyltransferase activity
SUN_0930	COG1309	transcriptional regulator
SUN_0932	COG1335	isochorismatase
SUN_0947	COG1942	4-Oxalocrotonate Tautomerase
SUN_0951	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SUN_0958	COG1840	ABC-type Fe3 transport system, periplasmic component
SUN_0961	COG1881	PFAM PEBP family protein
SUN_0963	COG0784	Response regulator, receiver
SUN_0963	COG4191	Histidine kinase
SUN_0965	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SUN_0966	COG0095	Lipoate-protein ligase
SUN_0967	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SUN_0968	COG0508	dehydrogenase complex catalyzes the overall conversion of
SUN_0969	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SUN_0970	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SUN_0971	COG0022	dehydrogenase e1 component
SUN_0971	COG0508	dehydrogenase complex catalyzes the overall conversion of
SUN_0973	COG0471	metal ion transport
SUN_0974	COG0471	metal ion transport
SUN_0977	COG1355	regulation of microtubule-based process
SUN_0978	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SUN_0979	COG2951	lytic endotransglycosylase activity
SUN_0982	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SUN_0983	COG3876	Protein conserved in bacteria
SUN_0987	COG2995	paraquat-inducible protein a
SUN_0988	COG3008	intermembrane lipid transfer
SUN_0988	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SUN_0994	COG1796	DNA polymerase
SUN_0994	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SUN_0995	COG2151	metal-sulfur cluster biosynthetic enzyme
SUN_0997	COG0719	Fe-S assembly protein
SUN_0998	COG0396	ATPase activity
SUN_0999	COG0719	Fe-S assembly protein
SUN_1001	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SUN_1003	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SUN_1005	COG1704	LemA family
SUN_1008	COG0343	queuine tRNA-ribosyltransferase activity
SUN_1010	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SUN_1012	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SUN_1013	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SUN_1015	COG1615	UPF0182 protein
SUN_1028	COG4581	dead DEAH box helicase
SUN_1030	COG0531	amino acid
SUN_1033	COG3228	Belongs to the MtfA family
SUN_1034	COG0531	amino acid
SUN_1036	COG0616	signal peptide processing
SUN_1037	COG0402	S-adenosylhomocysteine deaminase activity
SUN_1038	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SUN_1039	COG0006	proline dipeptidase activity
SUN_1040	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SUN_1041	COG1419	protein localization to endoplasmic reticulum
SUN_1043	COG0482	sulfurtransferase activity
SUN_1045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SUN_1046	COG0481	GTPase activity
SUN_1050	COG4251	negative regulation of phosphorylation
SUN_1050	COG2203	Gaf domain
SUN_1050	COG5001	Diguanylate cyclase
SUN_1050	COG3706	GGDEF domain
SUN_1061	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SUN_1062	COG1121	(ABC) transporter
SUN_1066	COG2198	Histidine kinase
SUN_1066	COG5002	protein histidine kinase activity
SUN_1066	COG0784	Response regulator, receiver
SUN_1067	COG0745	RESPONSE REGULATOR receiver
SUN_1072	COG1136	(ABC) transporter
SUN_1075	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SUN_1079	COG0688	phosphatidylethanolamine metabolic process
SUN_1081	COG0546	phosphoglycolate phosphatase activity
SUN_1084	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SUN_1086	COG4865	methylaspartate mutase activity
SUN_1088	COG0318	PFAM AMP-dependent synthetase and ligase
SUN_1090	COG0464	growth
SUN_1093	COG1943	Transposase
SUN_1096	COG1671	Belongs to the UPF0178 family
SUN_1097	COG4895	conserved protein (DUF2196)
SUN_1099	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SUN_1100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SUN_1102	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SUN_1107	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SUN_1109	COG1077	Cell shape determining protein MreB Mrl
SUN_1110	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SUN_1111	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SUN_1112	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SUN_1113	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SUN_1114	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SUN_1119	COG1757	Na H antiporter
SUN_1121	COG0306	phosphate transporter
SUN_1122	COG1283	sodium-dependent phosphate transmembrane transporter activity
SUN_1124	COG4716	Myosin-crossreactive antigen
SUN_1128	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SUN_1128	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SUN_1130	COG2827	Endonuclease containing a URI domain
SUN_1131	COG1022	Amp-dependent synthetase and ligase
SUN_1133	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
SUN_1134	COG1763	Mo-molybdopterin cofactor biosynthetic process
SUN_1137	COG0762	integral membrane protein
SUN_1138	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SUN_1139	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SUN_1141	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SUN_1141	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SUN_1143	COG0840	transmembrane signaling receptor activity
SUN_1144	COG0745	RESPONSE REGULATOR receiver
SUN_1146	COG3162	membrane
SUN_1147	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SUN_1149	COG2176	DNA-directed DNA polymerase activity
SUN_1150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SUN_1151	COG1573	uracil-dna glycosylase
SUN_1152	COG0667	Aldo Keto reductase
SUN_1154	COG0668	transmembrane transport
SUN_1157	COG1368	sulfuric ester hydrolase activity
SUN_1159	COG2226	methyltransferase
SUN_1160	COG3647	Membrane
SUN_1167	COG2081	HI0933 family
SUN_1168	COG0659	secondary active sulfate transmembrane transporter activity
SUN_1171	COG0521	Mo-molybdopterin cofactor biosynthetic process
SUN_1172	COG0300	oxidoreductase activity
SUN_1179	COG4948	Mandelate Racemase Muconate Lactonizing
SUN_1181	COG0742	ribosomal rna small subunit methyltransferase
SUN_1183	COG0590	tRNA wobble adenosine to inosine editing
SUN_1185	COG0745	RESPONSE REGULATOR receiver
SUN_1190	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SUN_1193	COG0585	pseudouridine synthase activity
SUN_1196	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SUN_1198	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SUN_1202	COG2048	Heterodisulfide reductase, subunit B
SUN_1205	COG3706	GGDEF domain
SUN_1207	COG1611	Belongs to the LOG family
SUN_1208	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SUN_1209	COG0508	dehydrogenase complex catalyzes the overall conversion of
SUN_1212	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SUN_1213	COG0148	phosphopyruvate hydratase activity
SUN_1214	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SUN_1214	COG0574	Belongs to the PEP-utilizing enzyme family
SUN_1220	COG0768	penicillin binding
SUN_1223	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SUN_1226	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SUN_1227	COG0131	Imidazoleglycerol-phosphate dehydratase
SUN_1228	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SUN_1230	COG0084	hydrolase, TatD family'
SUN_1232	COG0497	DNA recombination
SUN_1233	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SUN_1239	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SUN_1240	COG3178	'Phosphotransferase
SUN_1241	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SUN_1253	COG3012	SEC-C Motif Domain Protein
SUN_1254	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SUN_1257	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
SUN_1259	COG1254	Belongs to the acylphosphatase family
SUN_1263	COG0585	pseudouridine synthase activity
SUN_1264	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SUN_1265	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SUN_1268	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SUN_1269	COG0297	glycogen (starch) synthase activity
SUN_1270	COG1940	carbohydrate kinase activity
SUN_1271	COG0297	glycogen (starch) synthase activity
SUN_1273	COG1449	Belongs to the glycosyl hydrolase 57 family
SUN_1275	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SUN_1276	COG0166	Belongs to the GPI family
SUN_1278	COG0058	SHG alpha-glucan phosphorylase activity
SUN_1279	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SUN_1280	COG1993	acr, cog1993
SUN_1281	COG2095	MarC family integral membrane protein
SUN_1284	COG0450	alkyl hydroperoxide reductase
SUN_1288	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SUN_1289	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SUN_1290	COG0588	phosphoglycerate mutase activity
SUN_1293	COG1914	H( )-stimulated, divalent metal cation uptake system
SUN_1294	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SUN_1297	COG0513	Belongs to the DEAD box helicase family
SUN_1298	COG1227	inorganic diphosphatase activity
SUN_1299	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SUN_1304	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SUN_1305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SUN_1306	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SUN_1307	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SUN_1309	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SUN_1309	COG1333	cytochrome c biogenesis protein
SUN_1315	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SUN_1315	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SUN_1316	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SUN_1320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SUN_1322	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SUN_1323	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SUN_1325	COG0179	Fumarylacetoacetate (FAA) hydrolase
SUN_1327	COG2860	membrane
SUN_1329	COG1324	tolerance protein
SUN_1330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SUN_1334	COG2995	paraquat-inducible protein a
SUN_1335	COG2995	paraquat-inducible protein a
SUN_1336	COG3008	intermembrane lipid transfer
SUN_1336	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SUN_1339	COG0824	Thioesterase
SUN_1345	COG1566	PFAM secretion protein HlyD family protein
SUN_1347	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SUN_1350	COG1049	propionate catabolic process, 2-methylcitrate cycle
SUN_1351	COG1674	ftsk spoiiie
SUN_1351	COG1196	nuclear chromosome segregation
SUN_1352	COG0163	prenyltransferase activity
SUN_1353	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SUN_1354	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SUN_1355	COG0124	histidyl-tRNA synthetase
SUN_1358	COG1127	ABC transporter
SUN_1359	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SUN_1360	COG1166	arginine decarboxylase activity
SUN_1361	COG1045	serine acetyltransferase
SUN_1369	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SUN_1372	COG0772	Belongs to the SEDS family
SUN_1375	COG0525	valine-tRNA ligase activity
SUN_1377	COG3300	MHYT domain
SUN_1377	COG5001	Diguanylate cyclase
SUN_1381	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SUN_1383	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SUN_1387	COG1918	ferrous iron import across plasma membrane
SUN_1390	COG0745	RESPONSE REGULATOR receiver
SUN_1391	COG5002	protein histidine kinase activity
SUN_1395	COG2205	protein histidine kinase activity
SUN_1395	COG0784	Response regulator, receiver
SUN_1395	COG5002	protein histidine kinase activity
SUN_1402	COG1566	PFAM secretion protein HlyD family protein
SUN_1409	COG0670	Belongs to the BI1 family
SUN_1410	COG2010	Cytochrome c
SUN_1413	COG3119	arylsulfatase activity
SUN_1420	COG3678	ATP-independent chaperone mediated protein folding
SUN_1421	COG0745	RESPONSE REGULATOR receiver
SUN_1431	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
SUN_1432	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
SUN_1436	COG1968	undecaprenyl-diphosphatase activity
SUN_1437	COG1132	(ABC) transporter
SUN_1438	COG0582	viral genome integration into host DNA
SUN_1446	COG0644	oxidoreductase
SUN_1447	COG1234	tRNA 3'-trailer cleavage
SUN_1448	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SUN_1451	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SUN_1452	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SUN_1456	COG0731	radical SAM domain protein
SUN_1456	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SUN_1459	COG0542	response to heat
SUN_1460	COG0793	Belongs to the peptidase S41A family
SUN_1461	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SUN_1462	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SUN_1463	COG0047	phosphoribosylformylglycinamidine synthase activity
SUN_1469	COG2259	Doxx family
SUN_1472	COG0205	6-phosphofructokinase activity
SUN_1473	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SUN_1474	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SUN_1475	COG0488	(ABC) transporter
SUN_1482	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SUN_1482	COG0301	tRNA thio-modification
SUN_1483	COG1322	Protein conserved in bacteria
SUN_1485	COG0653	protein targeting
SUN_1486	COG4591	ABC-type transport system involved in lipoprotein release permease component
SUN_1489	COG0515	serine threonine protein kinase
SUN_1489	COG2815	serine threonine protein kinase
SUN_1491	COG2223	nitrite transmembrane transporter activity
SUN_1492	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SUN_1493	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SUN_1500	COG0243	molybdopterin cofactor binding
SUN_1506	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SUN_1507	COG0563	adenylate kinase activity
SUN_1510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SUN_1512	COG0123	including yeast histone deacetylase and acetoin utilization protein
SUN_1520	COG0277	FAD linked oxidase domain protein
SUN_1525	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SUN_1534	COG1696	Membrane protein involved in D-alanine export
SUN_1535	COG1216	Glycosyl transferase, family 2
SUN_1540	COG0463	Glycosyl transferase, family 2
SUN_1547	COG2244	polysaccharide biosynthetic process
SUN_1548	COG1045	serine acetyltransferase
SUN_1549	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SUN_1551	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SUN_1552	COG1088	dTDP-glucose 4,6-dehydratase activity
SUN_1554	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SUN_1555	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SUN_1556	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SUN_1558	COG4464	protein tyrosine phosphatase activity
SUN_1559	COG0489	protein tyrosine kinase activity
SUN_1561	COG0789	Transcriptional regulator
SUN_1562	COG0484	heat shock protein binding
SUN_1563	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SUN_1564	COG0138	bifunctional purine biosynthesis protein purh
SUN_1565	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SUN_1569	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SUN_1571	COG0706	membrane insertase activity
SUN_1572	COG0594	ribonuclease P activity
SUN_1573	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SUN_1576	COG0729	surface antigen
SUN_1577	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SUN_1579	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SUN_1580	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SUN_1582	COG0356	it plays a direct role in the translocation of protons across the membrane
SUN_1584	COG1137	ATPase activity
SUN_1585	COG0802	atpase or kinase
SUN_1586	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SUN_1587	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SUN_1588	COG2171	N-acyltransferase activity
SUN_1589	COG4206	TonB-dependent receptor
SUN_1594	COG2326	polyphosphate kinase activity
SUN_1606	COG3550	peptidyl-serine autophosphorylation
SUN_1607	COG0731	radical SAM domain protein
SUN_1613	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SUN_1615	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SUN_1617	COG0811	peptide transport
SUN_1618	COG0848	biopolymer transport protein
SUN_1619	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SUN_1621	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
SUN_1622	COG0217	transcriptional regulatory protein
SUN_1623	COG1388	LysM domain
SUN_1623	COG0741	lytic transglycosylase activity
SUN_1624	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SUN_1627	COG1858	cytochrome C peroxidase
SUN_1628	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SUN_1630	COG2833	Protein of unknown function (DUF455)
SUN_1632	COG1032	radical SAM domain protein
SUN_1633	COG2050	protein possibly involved in aromatic compounds catabolism
SUN_1633	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SUN_1638	COG0004	ammonium transporteR
SUN_1640	COG0004	ammonium transporteR
SUN_1644	COG0375	protein maturation
SUN_1645	COG1024	Enoyl-CoA hydratase
SUN_1645	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SUN_1646	COG0309	Hydrogenase expression formation protein (HypE)
SUN_1647	COG0409	Hydrogenase expression formation protein
SUN_1648	COG0298	carbon dioxide binding
SUN_1649	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SUN_1652	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
SUN_1653	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
SUN_1658	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SUN_1662	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
SUN_1663	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
SUN_1667	COG1739	Uncharacterized protein family UPF0029
SUN_1669	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SUN_1670	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
SUN_1675	COG4796	Type ii and iii secretion system protein
SUN_1680	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
SUN_1681	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
SUN_1682	COG0359	binds to the 23S rRNA
SUN_1683	COG0339	signal peptide processing
SUN_1685	COG0137	argininosuccinate synthase activity
SUN_1687	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SUN_1688	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SUN_1691	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SUN_1694	COG1610	YqeY-like protein
SUN_1695	COG0134	indole-3-glycerol-phosphate synthase activity
SUN_1700	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
SUN_1700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SUN_1703	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SUN_1704	COG0788	formyltetrahydrofolate deformylase activity
SUN_1705	COG0473	3-isopropylmalate dehydrogenase activity
SUN_1706	COG0066	3-isopropylmalate dehydratase activity
SUN_1707	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SUN_1713	COG1216	Glycosyl transferase, family 2
SUN_1714	COG1088	dTDP-glucose 4,6-dehydratase activity
SUN_1718	COG1218	3'(2'),5'-bisphosphate nucleotidase
SUN_1719	COG0529	Catalyzes the synthesis of activated sulfate
SUN_1721	COG2895	sulfate adenylyltransferase (ATP) activity
SUN_1722	COG0175	sulfate reduction
SUN_1729	COG1943	Transposase
SUN_1735	COG1216	Glycosyl transferase, family 2
SUN_1735	COG0438	transferase activity, transferring glycosyl groups
SUN_1741	COG0860	N-Acetylmuramoyl-L-alanine amidase
SUN_1742	COG0860	N-Acetylmuramoyl-L-alanine amidase
SUN_1744	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SUN_1745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SUN_1746	COG1758	RNA polymerase activity
SUN_1747	COG0528	UMP kinase activity
SUN_1750	COG2884	Cell division ATP-binding protein ftsE
SUN_1751	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SUN_1753	COG0564	pseudouridine synthase activity
SUN_1754	COG0037	tRNA processing
SUN_1755	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SUN_1756	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SUN_1759	COG1047	Peptidyl-prolyl cis-trans
SUN_1760	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SUN_1761	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SUN_1764	COG0823	Involved in the tonB-independent uptake of proteins
SUN_1765	COG2078	PFAM AMMECR1 domain protein
SUN_1766	COG1355	regulation of microtubule-based process
SUN_1768	COG0848	biopolymer transport protein
SUN_1769	COG0811	peptide transport
SUN_1770	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SUN_1771	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SUN_1772	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SUN_1773	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SUN_1774	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SUN_1775	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SUN_1777	COG1475	DNA binding
SUN_1778	COG1192	Involved in chromosome partitioning
SUN_1780	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SUN_1781	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SUN_1782	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SUN_1783	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SUN_1784	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SUN_1785	COG0251	oxidation-reduction process
SUN_1787	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SUN_1790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SUN_1793	COG3549	Plasmid maintenance system killer
SUN_1794	COG0517	IMP dehydrogenase activity
SUN_1794	COG0516	GMP reductase activity
SUN_1795	COG0154	amidase activity
SUN_1796	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SUN_1800	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SUN_1802	COG0191	fructose-bisphosphate aldolase activity
SUN_1805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SUN_1806	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SUN_1808	COG2195	Cleaves the N-terminal amino acid of tripeptides
SUN_1812	COG3869	Catalyzes the specific phosphorylation of arginine residues in
SUN_1813	COG0133	tryptophan synthase activity
SUN_1816	COG0488	(ABC) transporter
SUN_1818	COG1410	methionine synthase
SUN_1818	COG0646	methionine synthase
SUN_1819	COG1366	Belongs to the anti-sigma-factor antagonist family
SUN_1821	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SUN_1822	COG0440	acetolactate synthase activity
SUN_1823	COG0028	Belongs to the TPP enzyme family
SUN_1824	COG3852	Histidine kinase
SUN_1827	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SUN_1828	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SUN_1829	COG0709	Synthesizes selenophosphate from selenide and ATP
SUN_1831	COG1832	CoA-binding protein
SUN_1832	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SUN_1834	COG2198	Histidine kinase
SUN_1834	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SUN_1834	COG0784	Response regulator, receiver
SUN_1834	COG2205	protein histidine kinase activity
SUN_1836	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SUN_1838	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SUN_1839	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SUN_1842	COG0784	Response regulator, receiver
SUN_1842	COG2205	protein histidine kinase activity
SUN_1842	COG5002	protein histidine kinase activity
SUN_1853	COG2996	Protein conserved in bacteria
SUN_1855	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SUN_1856	COG1234	tRNA 3'-trailer cleavage
SUN_1858	COG4232	protein-disulfide reductase activity
SUN_1859	COG1331	Highly conserved protein containing a thioredoxin domain
SUN_1867	COG0517	IMP dehydrogenase activity
SUN_1868	COG2205	protein histidine kinase activity
SUN_1869	COG0745	RESPONSE REGULATOR receiver
SUN_1872	COG0443	Heat shock 70 kDa protein
SUN_1873	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SUN_1874	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SUN_1875	COG1959	2 iron, 2 sulfur cluster binding
SUN_1876	COG2404	hydrolase activity, acting on ester bonds
SUN_1877	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SUN_1879	COG0484	heat shock protein binding
SUN_1880	COG1592	Rubrerythrin
SUN_1882	COG0776	regulation of translation
SUN_1883	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SUN_1886	COG1185	polyribonucleotide nucleotidyltransferase activity
SUN_1888	COG0484	heat shock protein binding
SUN_1890	COG1714	RDD family
SUN_1891	COG0151	Belongs to the GarS family
SUN_1894	COG0326	Molecular chaperone. Has ATPase activity
SUN_1897	COG0519	Catalyzes the synthesis of GMP from XMP
SUN_1897	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SUN_1899	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SUN_1901	COG0322	excinuclease ABC activity
SUN_1902	COG0840	transmembrane signaling receptor activity
SUN_1905	COG0745	RESPONSE REGULATOR receiver
SUN_1905	COG3706	GGDEF domain
SUN_1906	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SUN_1912	COG4968	Prepilin-type N-terminal cleavage methylation domain
SUN_1913	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SUN_1915	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SUN_1917	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SUN_1918	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SUN_1919	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SUN_1920	COG2877	3-deoxy-8-phosphooctulonate synthase activity
SUN_1923	COG0668	transmembrane transport
SUN_1924	COG1160	GTP binding
SUN_1925	COG0180	Tryptophanyl-tRNA synthetase
SUN_1926	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SUN_1927	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SUN_1928	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SUN_1930	COG2217	Heavy metal translocating P-type atpase
SUN_1933	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SUN_1934	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SUN_1935	COG0166	Belongs to the GPI family
SUN_1937	COG3328	transposase activity
SUN_1943	COG1132	(ABC) transporter
SUN_1950	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SUN_1951	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SUN_1952	COG2264	protein methyltransferase activity
SUN_1953	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SUN_1954	COG1183	phosphatidylcholine synthase activity
SUN_1956	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SUN_1957	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SUN_1963	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SUN_1964	COG0459	protein refolding
SUN_1965	COG5001	Diguanylate cyclase
SUN_1965	COG3300	MHYT domain
SUN_1966	COG1570	exodeoxyribonuclease VII activity
SUN_1967	COG2226	methyltransferase
SUN_1968	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SUN_1968	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SUN_1969	COG0779	Required for maturation of 30S ribosomal subunits
SUN_1970	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SUN_1971	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SUN_1973	COG0083	homoserine kinase activity
SUN_1975	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SUN_1978	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SUN_1979	COG0157	Belongs to the NadC ModD family
SUN_1980	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SUN_1981	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SUN_1983	COG0745	RESPONSE REGULATOR receiver
SUN_1984	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SUN_1986	COG0069	glutamate synthase activity
SUN_1991	COG1566	PFAM secretion protein HlyD family protein
SUN_1995	COG0857	belongs to the CobB CobQ family
SUN_1995	COG0280	phosphate acetyltransferase
SUN_1996	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SUN_1997	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SUN_1998	COG0287	Prephenate dehydrogenase
SUN_2006	COG0714	Associated with various cellular activities
SUN_2036	COG0737	Belongs to the 5'-nucleotidase family
SUN_2039	COG0745	RESPONSE REGULATOR receiver
SUN_2041	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SUN_2042	COG0285	dihydrofolate synthase activity
SUN_2044	COG0495	leucyl-tRNA aminoacylation
SUN_2045	COG2321	neutral zinc metallopeptidase
SUN_2046	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SUN_2047	COG1692	metallophosphoesterase
SUN_2048	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SUN_2049	COG0416	fatty acid biosynthetic process
SUN_2050	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SUN_2052	COG0105	UTP biosynthetic process
SUN_2053	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SUN_2054	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SUN_2055	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SUN_2056	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SUN_2057	COG1605	Chorismate mutase
SUN_2057	COG0077	Prephenate dehydratase
SUN_2058	COG0019	diaminopimelate decarboxylase activity
SUN_2060	COG0193	aminoacyl-tRNA hydrolase activity
SUN_2061	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SUN_2063	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SUN_2066	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SUN_2067	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SUN_2068	COG0540	Belongs to the ATCase OTCase family
SUN_2069	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SUN_2072	COG0705	Rhomboid family
SUN_2075	COG0357	Ribosomal RNA small subunit methyltransferase G
SUN_2080	COG1132	(ABC) transporter
SUN_2088	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SUN_2089	COG0113	porphobilinogen synthase activity
SUN_2090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SUN_2091	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SUN_2092	COG0247	lactate metabolic process
SUN_2093	COG5002	protein histidine kinase activity
SUN_2094	COG0745	RESPONSE REGULATOR receiver
SUN_2095	COG0628	permease
SUN_2096	COG2255	four-way junction helicase activity
SUN_2097	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SUN_2098	COG0159	tryptophan synthase activity
SUN_2099	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SUN_2100	COG1924	4 iron, 4 sulfur cluster binding
SUN_2102	COG3842	ATPase activity
SUN_2123	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SUN_2128	COG0741	lytic transglycosylase activity
SUN_2128	COG0739	heme binding
SUN_2128	COG1196	nuclear chromosome segregation
SUN_2130	COG0277	FAD linked oxidase domain protein
SUN_2131	COG1295	ribonuclease BN
SUN_2134	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SUN_2135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SUN_2137	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SUN_2140	COG0028	Belongs to the TPP enzyme family
SUN_2143	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SUN_2146	COG0463	Glycosyl transferase, family 2
SUN_2148	COG4969	Belongs to the N-Me-Phe pilin family
SUN_2151	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SUN_2153	COG0556	nucleotide-excision repair
SUN_2155	COG0135	phosphoribosylanthranilate isomerase activity
SUN_2156	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SUN_2157	COG0668	transmembrane transport
SUN_2158	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SUN_2159	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SUN_2160	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SUN_2162	COG0513	Belongs to the DEAD box helicase family
SUN_2163	COG0586	Pfam SNARE associated Golgi protein
SUN_2164	COG0825	malonyl-CoA metabolic process
SUN_2165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SUN_2166	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SUN_2168	COG0840	transmembrane signaling receptor activity
SUN_2172	COG1121	(ABC) transporter
SUN_2173	COG0348	domain, Protein
SUN_2176	COG0437	4 iron, 4 sulfur cluster binding
SUN_2182	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SUN_2183	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SUN_2186	COG4191	Histidine kinase
SUN_2186	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SUN_2187	COG0745	RESPONSE REGULATOR receiver
SUN_2191	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SUN_2192	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SUN_2195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SUN_2196	COG0037	tRNA processing
SUN_2197	COG4974	Belongs to the 'phage' integrase family
SUN_2198	COG2121	Domain of unknown function (DUF374)
SUN_2199	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SUN_2201	COG0195	Participates in both transcription termination and antitermination
SUN_2202	COG0149	triose-phosphate isomerase activity
SUN_2203	COG0126	phosphoglycerate kinase activity
SUN_2204	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SUN_2205	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SUN_2209	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SUN_2210	COG0194	GDP metabolic process
SUN_2215	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SUN_2216	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SUN_2217	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SUN_2218	COG1007	ATP synthesis coupled electron transport
SUN_2220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SUN_2221	COG0713	ATP synthesis coupled electron transport
SUN_2222	COG0839	Belongs to the complex I subunit 6 family
SUN_2223	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SUN_2224	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SUN_2229	COG0649	NAD binding
SUN_2230	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SUN_2231	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SUN_2232	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SUN_2235	COG1943	Transposase
SUN_2236	COG1222	aaa ATPase
SUN_2242	COG2205	protein histidine kinase activity
SUN_2244	COG2190	(PTS) system
SUN_2246	COG0318	PFAM AMP-dependent synthetase and ligase
SUN_2249	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SUN_2255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SUN_2256	COG0358	DNA primase activity
SUN_2258	COG0328	RNA-DNA hybrid ribonuclease activity
SUN_2259	COG0571	ribonuclease III activity
SUN_2260	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SUN_2262	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SUN_2264	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SUN_2265	COG1943	Transposase
SUN_2266	COG0514	ATP-dependent DNA helicase (RecQ)
SUN_2267	COG0745	RESPONSE REGULATOR receiver
SUN_2269	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SUN_2270	COG0581	inorganic phosphate transmembrane transporter activity
SUN_2272	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SUN_2273	COG0745	RESPONSE REGULATOR receiver
SUN_2274	COG0306	phosphate transporter
SUN_2278	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SUN_2279	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SUN_2285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SUN_2290	COG2989	Protein conserved in bacteria
SUN_2294	COG0582	viral genome integration into host DNA
SUN_2296	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SUN_2320	COG0051	transcription antitermination factor activity, RNA binding
SUN_2321	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SUN_2322	COG0088	Forms part of the polypeptide exit tunnel
SUN_2323	COG0089	rRNA binding
SUN_2324	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SUN_2325	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SUN_2326	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SUN_2327	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SUN_2328	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SUN_2329	COG0255	Belongs to the universal ribosomal protein uL29 family
SUN_2330	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SUN_2331	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SUN_2332	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SUN_2333	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SUN_2334	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SUN_2335	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SUN_2336	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SUN_2337	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SUN_2338	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SUN_2339	COG0200	Binds to the 23S rRNA
SUN_2340	COG0201	protein transport
SUN_2341	COG0024	Methionine aminopeptidase
SUN_2342	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SUN_2343	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SUN_2344	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SUN_2345	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SUN_2346	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SUN_2347	COG0202	RNA polymerase activity
SUN_2348	COG0203	ribosomal protein L17
SUN_2352	COG2259	Doxx family
SUN_2355	COG0791	NLP P60 protein
SUN_2357	COG2081	HI0933 family
SUN_2358	COG0011	TIGRFAM Protein of
SUN_2360	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SUN_2361	COG1115	amino acid carrier protein
SUN_2363	COG1187	pseudouridine synthase activity
SUN_2364	COG0517	IMP dehydrogenase activity
SUN_2364	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SUN_2366	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SUN_2367	COG0107	imidazoleglycerol-phosphate synthase activity
SUN_2369	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SUN_2370	COG0564	pseudouridine synthase activity
SUN_2371	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SUN_2372	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SUN_2375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SUN_2379	COG4191	Histidine kinase
SUN_2380	COG0745	RESPONSE REGULATOR receiver
SUN_2381	COG3119	arylsulfatase activity
SUN_2386	COG0714	Associated with various cellular activities
SUN_2389	COG2304	oxidoreductase activity
SUN_2395	COG0372	Belongs to the citrate synthase family
SUN_2396	COG3123	guanosine phosphorylase activity
SUN_2398	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SUN_2400	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SUN_2402	COG0387	Pfam Sodium calcium exchanger
SUN_2404	COG0714	Associated with various cellular activities
SUN_2409	COG0237	dephospho-CoA kinase activity
SUN_2410	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SUN_2412	COG0582	viral genome integration into host DNA
SUN_2425	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SUN_2426	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SUN_2427	COG0129	dihydroxy-acid dehydratase activity
SUN_2434	COG1403	HNH endonuclease
SUN_2445	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
SUN_2453	COG3328	transposase activity
SUN_2456	COG1228	amidohydrolase
SUN_2457	COG4932	domain protein
SUN_2457	COG5492	domain, Protein
SUN_2459	COG0745	RESPONSE REGULATOR receiver
SUN_2460	COG4191	Histidine kinase
SUN_2465	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SUN_2466	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group