locus-tag	class	description
SUTMEG_00010	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SUTMEG_00020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SUTMEG_00030	COG2011	ABC-type metal ion transport system permease component
SUTMEG_00040	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SUTMEG_00050	COG1968	undecaprenyl-diphosphatase activity
SUTMEG_00060	COG3318	Belongs to the UPF0149 family
SUTMEG_00060	COG3012	SEC-C Motif Domain Protein
SUTMEG_00070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SUTMEG_00070	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
SUTMEG_00080	COG0488	(ABC) transporter
SUTMEG_00110	COG0589	response to stress
SUTMEG_00120	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SUTMEG_00160	COG4783	chaperone-mediated protein folding
SUTMEG_00170	COG0492	ferredoxin-NADP+ reductase activity
SUTMEG_00180	COG0489	protein tyrosine kinase activity
SUTMEG_00190	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SUTMEG_00190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SUTMEG_00200	COG0659	secondary active sulfate transmembrane transporter activity
SUTMEG_00210	COG1464	Belongs to the NlpA lipoprotein family
SUTMEG_00260	COG0823	Involved in the tonB-independent uptake of proteins
SUTMEG_00290	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SUTMEG_00300	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SUTMEG_00320	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
SUTMEG_00330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SUTMEG_00340	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SUTMEG_00370	COG0751	glycine-tRNA ligase activity
SUTMEG_00380	COG0752	glycyl-tRNA synthetase alpha subunit
SUTMEG_00390	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SUTMEG_00400	COG4535	Mg2 and Co2 transporter CorC
SUTMEG_00410	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SUTMEG_00420	COG1702	phosphate starvation-inducible protein PhoH
SUTMEG_00430	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SUTMEG_00440	COG0351	phosphomethylpyrimidine kinase
SUTMEG_00460	COG0859	PFAM glycosyl transferase family 9
SUTMEG_00490	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SUTMEG_00500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SUTMEG_00510	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SUTMEG_00520	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SUTMEG_00530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SUTMEG_00540	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SUTMEG_00560	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SUTMEG_00570	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SUTMEG_00600	COG1752	Esterase of the alpha-beta hydrolase superfamily
SUTMEG_00610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SUTMEG_00640	COG2814	Major facilitator Superfamily
SUTMEG_00650	COG0629	single-stranded DNA binding
SUTMEG_00660	COG1136	(ABC) transporter
SUTMEG_00660	COG0577	efflux transmembrane transporter activity
SUTMEG_00670	COG0577	efflux transmembrane transporter activity
SUTMEG_00670	COG1136	(ABC) transporter
SUTMEG_00700	COG0745	RESPONSE REGULATOR receiver
SUTMEG_00710	COG2205	protein histidine kinase activity
SUTMEG_00720	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SUTMEG_00750	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SUTMEG_00790	COG0235	Class ii aldolase
SUTMEG_00800	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SUTMEG_00810	COG0045	succinate-CoA ligase (ADP-forming) activity
SUTMEG_00810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SUTMEG_00810	COG1042	CoA-binding domain protein
SUTMEG_00820	COG1024	Enoyl-CoA hydratase
SUTMEG_00840	COG0765	amino acid transport
SUTMEG_00850	COG0765	amino acid transport
SUTMEG_00860	COG1126	abc transporter atp-binding protein
SUTMEG_00880	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SUTMEG_00910	COG1137	ATPase activity
SUTMEG_00920	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
SUTMEG_00930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SUTMEG_00950	COG1194	a g-specific adenine glycosylase
SUTMEG_00970	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
SUTMEG_00980	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SUTMEG_00990	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SUTMEG_01000	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SUTMEG_01020	COG0193	aminoacyl-tRNA hydrolase activity
SUTMEG_01030	COG0012	GTP binding
SUTMEG_01050	COG0450	alkyl hydroperoxide reductase
SUTMEG_01070	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SUTMEG_01080	COG0742	ribosomal rna small subunit methyltransferase
SUTMEG_01100	COG0248	Ppx GppA phosphatase
SUTMEG_01110	COG2884	Cell division ATP-binding protein ftsE
SUTMEG_01140	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SUTMEG_01150	COG2197	response regulator
SUTMEG_01160	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
SUTMEG_01170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SUTMEG_01180	COG4942	peptidase
SUTMEG_01190	COG0793	Belongs to the peptidase S41A family
SUTMEG_01200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SUTMEG_01210	COG0616	signal peptide processing
SUTMEG_01230	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SUTMEG_01240	COG0523	cobalamin synthesis protein
SUTMEG_01260	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SUTMEG_01270	COG1560	Kdo2-lipid A biosynthetic process
SUTMEG_01290	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SUTMEG_01300	COG0180	Tryptophanyl-tRNA synthetase
SUTMEG_01310	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SUTMEG_01320	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SUTMEG_01330	COG0741	lytic transglycosylase activity
SUTMEG_01340	COG0617	tRNA 3'-terminal CCA addition
SUTMEG_01380	COG0517	IMP dehydrogenase activity
SUTMEG_01380	COG0516	GMP reductase activity
SUTMEG_01390	COG2326	polyphosphate kinase activity
SUTMEG_01430	COG1022	Amp-dependent synthetase and ligase
SUTMEG_01440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SUTMEG_01450	COG4624	Iron only hydrogenase large subunit, C-terminal domain
SUTMEG_01450	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SUTMEG_01460	COG4624	Iron only hydrogenase large subunit, C-terminal domain
SUTMEG_01490	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SUTMEG_01500	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SUTMEG_01510	COG2233	PERMEase
SUTMEG_01520	COG2183	response to ionizing radiation
SUTMEG_01540	COG0765	amino acid transport
SUTMEG_01550	COG4597	amino acid ABC transporter
SUTMEG_01560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SUTMEG_01570	COG1253	flavin adenine dinucleotide binding
SUTMEG_01600	COG0242	peptide deformylase activity
SUTMEG_01620	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SUTMEG_01630	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SUTMEG_01630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SUTMEG_01650	COG5000	phosphorelay sensor kinase activity
SUTMEG_01660	COG2204	response regulator
SUTMEG_01670	COG0569	domain protein
SUTMEG_01680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SUTMEG_01710	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SUTMEG_01720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SUTMEG_01740	COG2211	Major facilitator Superfamily
SUTMEG_01750	COG1187	pseudouridine synthase activity
SUTMEG_01760	COG0708	Exodeoxyribonuclease III
SUTMEG_01770	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SUTMEG_01780	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SUTMEG_01800	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SUTMEG_01810	COG1077	Cell shape determining protein MreB Mrl
SUTMEG_01840	COG0768	penicillin binding
SUTMEG_01850	COG0772	Belongs to the SEDS family
SUTMEG_01910	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SUTMEG_01940	COG2921	Belongs to the UPF0250 family
SUTMEG_01950	COG1575	Belongs to the MenA family. Type 1 subfamily
SUTMEG_01960	COG2823	Periplasmic or secreted lipoprotein
SUTMEG_02030	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SUTMEG_02050	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SUTMEG_02080	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SUTMEG_02090	COG0445	tRNA wobble uridine modification
SUTMEG_02100	COG0357	Ribosomal RNA small subunit methyltransferase G
SUTMEG_02120	COG1192	Involved in chromosome partitioning
SUTMEG_02130	COG1475	DNA binding
SUTMEG_02150	COG0356	it plays a direct role in the translocation of protons across the membrane
SUTMEG_02180	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SUTMEG_02190	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SUTMEG_02200	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SUTMEG_02210	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SUTMEG_02220	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SUTMEG_02240	COG1872	DUF167
SUTMEG_02250	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SUTMEG_02260	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SUTMEG_02280	COG2226	methyltransferase
SUTMEG_02310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SUTMEG_02320	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SUTMEG_02360	COG1538	Outer membrane efflux protein
SUTMEG_02380	COG1301	dicarboxylic acid transport
SUTMEG_02390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SUTMEG_02400	COG0642	Histidine kinase
SUTMEG_02410	COG0745	RESPONSE REGULATOR receiver
SUTMEG_02440	COG4681	YaeQ
SUTMEG_02450	COG2346	COG2346, Truncated hemoglobins
SUTMEG_02470	COG1294	oxidase, subunit
SUTMEG_02510	COG2267	carboxylic ester hydrolase activity
SUTMEG_02550	COG0674	pyruvate-flavodoxin oxidoreductase activity
SUTMEG_02560	COG1013	pyruvate-flavodoxin oxidoreductase activity
SUTMEG_02580	COG3850	Histidine kinase
SUTMEG_02590	COG2197	response regulator
SUTMEG_02610	COG0348	domain, Protein
SUTMEG_02620	COG0437	4 iron, 4 sulfur cluster binding
SUTMEG_02630	COG0243	molybdopterin cofactor binding
SUTMEG_02670	COG0514	ATP-dependent DNA helicase (RecQ)
SUTMEG_02680	COG4221	oxidoreductase activity
SUTMEG_02690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SUTMEG_02710	COG0018	arginyl-trna synthetase
SUTMEG_02720	COG1469	GTP cyclohydrolase I activity
SUTMEG_02750	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SUTMEG_02760	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SUTMEG_02790	COG0081	regulation of translation
SUTMEG_02800	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SUTMEG_02810	COG0222	ribosome binding
SUTMEG_02820	COG0085	RNA polymerase activity
SUTMEG_02830	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SUTMEG_02840	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SUTMEG_02850	COG0049	tRNA binding
SUTMEG_02860	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SUTMEG_02870	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SUTMEG_02880	COG0051	transcription antitermination factor activity, RNA binding
SUTMEG_02890	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SUTMEG_02900	COG0088	Forms part of the polypeptide exit tunnel
SUTMEG_02910	COG0089	rRNA binding
SUTMEG_02920	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SUTMEG_02930	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SUTMEG_02940	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SUTMEG_02950	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SUTMEG_02960	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SUTMEG_02970	COG0255	Belongs to the universal ribosomal protein uL29 family
SUTMEG_02980	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SUTMEG_02990	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SUTMEG_03000	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SUTMEG_03010	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SUTMEG_03020	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SUTMEG_03030	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SUTMEG_03040	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SUTMEG_03050	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SUTMEG_03060	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SUTMEG_03070	COG1841	ribosomal large subunit assembly
SUTMEG_03080	COG0200	Binds to the 23S rRNA
SUTMEG_03090	COG0201	protein transport
SUTMEG_03100	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SUTMEG_03110	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SUTMEG_03120	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SUTMEG_03140	COG0202	RNA polymerase activity
SUTMEG_03150	COG0203	ribosomal protein L17
SUTMEG_03160	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SUTMEG_03180	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SUTMEG_03190	COG0516	GMP reductase activity
SUTMEG_03210	COG1965	Belongs to the frataxin family
SUTMEG_03240	COG1127	ABC transporter
SUTMEG_03250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SUTMEG_03260	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SUTMEG_03270	COG2853	Lipoprotein
SUTMEG_03300	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SUTMEG_03330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SUTMEG_03340	COG0805	protein transport
SUTMEG_03350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SUTMEG_03360	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SUTMEG_03370	COG0625	glutathione transferase activity
SUTMEG_03390	COG2890	protein-(glutamine-N5) methyltransferase activity
SUTMEG_03400	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SUTMEG_03410	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SUTMEG_03430	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SUTMEG_03440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SUTMEG_03470	COG0546	phosphoglycolate phosphatase activity
SUTMEG_03490	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SUTMEG_03530	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SUTMEG_03560	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SUTMEG_03570	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SUTMEG_03580	COG2095	MarC family integral membrane protein
SUTMEG_03590	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SUTMEG_03600	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SUTMEG_03610	COG0316	Belongs to the HesB IscA family
SUTMEG_03620	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SUTMEG_03630	COG0739	heme binding
SUTMEG_03660	COG1490	D-aminoacyl-tRNA deacylase activity
SUTMEG_03690	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SUTMEG_03700	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SUTMEG_03700	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SUTMEG_03720	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SUTMEG_03730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SUTMEG_03750	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
SUTMEG_03760	COG1058	Belongs to the CinA family
SUTMEG_03760	COG1546	Belongs to the CinA family
SUTMEG_03770	COG1253	flavin adenine dinucleotide binding
SUTMEG_03790	COG0284	orotidine-5'-phosphate decarboxylase activity
SUTMEG_03820	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SUTMEG_03830	COG2027	D-alanyl-D-alanine carboxypeptidase
SUTMEG_03850	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SUTMEG_03870	COG2001	Belongs to the MraZ family
SUTMEG_03880	COG0275	rRNA processing
SUTMEG_03910	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SUTMEG_03920	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SUTMEG_03930	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SUTMEG_03940	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SUTMEG_03960	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SUTMEG_03980	COG1181	Belongs to the D-alanine--D-alanine ligase family
SUTMEG_03990	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SUTMEG_04000	COG0849	cell division
SUTMEG_04010	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SUTMEG_04040	COG0653	protein targeting
SUTMEG_04060	COG0494	nUDIX hydrolase
SUTMEG_04070	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
SUTMEG_04090	COG0237	dephospho-CoA kinase activity
SUTMEG_04100	COG0142	geranyltranstransferase activity
SUTMEG_04120	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SUTMEG_04130	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SUTMEG_04150	COG0442	prolyl-tRNA aminoacylation
SUTMEG_04180	COG0811	peptide transport
SUTMEG_04190	COG0824	Thioesterase
SUTMEG_04210	COG2255	four-way junction helicase activity
SUTMEG_04220	COG0632	four-way junction helicase activity
SUTMEG_04230	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SUTMEG_04240	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SUTMEG_04250	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SUTMEG_04280	COG0762	integral membrane protein
SUTMEG_04310	COG2264	protein methyltransferase activity
SUTMEG_04320	COG0439	Biotin carboxylase
SUTMEG_04330	COG0511	ligase activity, forming carbon-carbon bonds
SUTMEG_04350	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SUTMEG_04360	COG3150	esterase
SUTMEG_04370	COG0557	exoribonuclease II activity
SUTMEG_04380	COG2239	Acts as a magnesium transporter
SUTMEG_04400	COG1196	nuclear chromosome segregation
SUTMEG_04400	COG0739	heme binding
SUTMEG_04400	COG0741	lytic transglycosylase activity
SUTMEG_04420	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SUTMEG_04430	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SUTMEG_04440	COG0126	phosphoglycerate kinase activity
SUTMEG_04450	COG2195	Cleaves the N-terminal amino acid of tripeptides
SUTMEG_04460	COG1216	Glycosyl transferase, family 2
SUTMEG_04460	COG1442	glycosyl transferase family 8
SUTMEG_04490	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SUTMEG_04500	COG0586	Pfam SNARE associated Golgi protein
SUTMEG_04510	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SUTMEG_04520	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SUTMEG_04530	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SUTMEG_04560	COG0617	tRNA 3'-terminal CCA addition
SUTMEG_04570	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SUTMEG_04590	COG0521	Mo-molybdopterin cofactor biosynthetic process
SUTMEG_04600	COG3028	Belongs to the UPF0307 family
SUTMEG_04610	COG0312	modulator of DNA gyrase
SUTMEG_04620	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SUTMEG_04630	COG0343	queuine tRNA-ribosyltransferase activity
SUTMEG_04640	COG1862	Preprotein translocase
SUTMEG_04650	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SUTMEG_04660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SUTMEG_04710	COG2194	sulfuric ester hydrolase activity
SUTMEG_04720	COG0352	thiamine-phosphate diphosphorylase activity
SUTMEG_04730	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SUTMEG_04750	COG0730	response to heat
SUTMEG_04770	COG1216	Glycosyl transferase, family 2
SUTMEG_04800	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SUTMEG_04820	COG0328	RNA-DNA hybrid ribonuclease activity
SUTMEG_04890	COG1132	(ABC) transporter
SUTMEG_04900	COG1760	l-serine dehydratase
SUTMEG_04920	COG1530	ribonuclease E activity
SUTMEG_04930	COG2925	Exonuclease
SUTMEG_04950	COG2084	Dehydrogenase
SUTMEG_04960	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SUTMEG_04980	COG1477	protein flavinylation
SUTMEG_05020	COG0497	DNA recombination
SUTMEG_05030	COG1115	amino acid carrier protein
SUTMEG_05040	COG0165	Argininosuccinate lyase
SUTMEG_05060	COG0525	valine-tRNA ligase activity
SUTMEG_05090	COG1053	succinate dehydrogenase
SUTMEG_05090	COG3976	FMN-binding domain protein
SUTMEG_05110	COG1053	succinate dehydrogenase
SUTMEG_05160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SUTMEG_05170	COG1758	RNA polymerase activity
SUTMEG_05190	COG1561	YicC-like family, N-terminal region
SUTMEG_05210	COG1053	succinate dehydrogenase
SUTMEG_05220	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SUTMEG_05230	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SUTMEG_05240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SUTMEG_05260	COG3852	Histidine kinase
SUTMEG_05270	COG2204	response regulator
SUTMEG_05290	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SUTMEG_05350	COG0708	Exodeoxyribonuclease III
SUTMEG_05370	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SUTMEG_05380	COG4566	intracellular signal transduction
SUTMEG_05410	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
SUTMEG_05420	COG1643	Atp-dependent helicase
SUTMEG_05440	COG0247	lactate metabolic process
SUTMEG_05440	COG2181	nitrate reductase activity
SUTMEG_05450	COG0167	dihydroorotate dehydrogenase activity
SUTMEG_05470	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SUTMEG_05480	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SUTMEG_05490	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SUTMEG_05500	COG1187	pseudouridine synthase activity
SUTMEG_05510	COG0779	Required for maturation of 30S ribosomal subunits
SUTMEG_05520	COG2251	uridine kinase activity
SUTMEG_05520	COG0195	Participates in both transcription termination and antitermination
SUTMEG_05530	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SUTMEG_05540	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SUTMEG_05570	COG3012	SEC-C Motif Domain Protein
SUTMEG_05600	COG0165	Argininosuccinate lyase
SUTMEG_05610	COG3069	C4-dicarboxylate transmembrane transporter activity
SUTMEG_05630	COG0277	FAD linked oxidase domain protein
SUTMEG_05640	COG0563	adenylate kinase activity
SUTMEG_05650	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
SUTMEG_05670	COG1663	tetraacyldisaccharide 4'-kinase activity
SUTMEG_05680	COG1570	exodeoxyribonuclease VII activity
SUTMEG_05690	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SUTMEG_05720	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SUTMEG_05730	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SUTMEG_05740	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SUTMEG_05750	COG0196	riboflavin kinase activity
SUTMEG_05760	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SUTMEG_05770	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SUTMEG_05770	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SUTMEG_05780	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SUTMEG_05800	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SUTMEG_05810	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SUTMEG_05820	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SUTMEG_05830	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SUTMEG_05840	COG1610	YqeY-like protein
SUTMEG_05850	COG1114	Component of the transport system for branched-chain amino acids
SUTMEG_05890	COG0513	Belongs to the DEAD box helicase family
SUTMEG_05900	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SUTMEG_05900	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SUTMEG_05920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SUTMEG_05960	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SUTMEG_05980	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SUTMEG_05990	COG1653	transport
SUTMEG_06000	COG1175	transmembrane transport
SUTMEG_06010	COG0395	ABC-type sugar transport system, permease component
SUTMEG_06030	COG1238	metal cluster binding
SUTMEG_06060	COG0228	four-way junction DNA binding
SUTMEG_06070	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SUTMEG_06080	COG0336	Belongs to the RNA methyltransferase TrmD family
SUTMEG_06090	COG0335	large ribosomal subunit rRNA binding
SUTMEG_06120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SUTMEG_06120	COG1017	nitric oxide dioxygenase activity
SUTMEG_06130	COG2032	superoxide dismutase activity
SUTMEG_06140	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SUTMEG_06170	COG0495	leucyl-tRNA aminoacylation
SUTMEG_06180	COG0210	DNA helicase
SUTMEG_06190	COG3069	C4-dicarboxylate transmembrane transporter activity
SUTMEG_06220	COG0252	asparaginase activity
SUTMEG_06230	COG0137	argininosuccinate synthase activity
SUTMEG_06240	COG1230	cation diffusion facilitator family transporter
SUTMEG_06250	COG0504	CTP synthase activity
SUTMEG_06260	COG2877	3-deoxy-8-phosphooctulonate synthase activity
SUTMEG_06270	COG0148	phosphopyruvate hydratase activity
SUTMEG_06280	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
SUTMEG_06290	COG0642	Histidine kinase
SUTMEG_06300	COG0745	RESPONSE REGULATOR receiver
SUTMEG_06360	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SUTMEG_06370	COG0613	PHP domain protein
SUTMEG_06380	COG1994	Peptidase M50
SUTMEG_06400	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
SUTMEG_06440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SUTMEG_06450	COG2814	Major facilitator Superfamily
SUTMEG_06470	COG0564	pseudouridine synthase activity
SUTMEG_06480	COG1530	ribonuclease E activity
SUTMEG_06560	COG1053	succinate dehydrogenase
SUTMEG_06580	COG0437	4 iron, 4 sulfur cluster binding
SUTMEG_06620	COG1301	dicarboxylic acid transport
SUTMEG_06650	COG1053	succinate dehydrogenase
SUTMEG_06650	COG3976	FMN-binding domain protein
SUTMEG_06680	COG3976	FMN-binding domain protein
SUTMEG_06680	COG1053	succinate dehydrogenase
SUTMEG_06710	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
SUTMEG_06720	COG0165	Argininosuccinate lyase
SUTMEG_06760	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SUTMEG_06770	COG0420	3'-5' exonuclease activity
SUTMEG_06780	COG0419	ATPase involved in DNA repair
SUTMEG_06800	COG0477	Major facilitator Superfamily
SUTMEG_06810	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SUTMEG_06840	COG0667	Aldo Keto reductase
SUTMEG_06880	COG4953	penicillin-binding protein 1C
SUTMEG_06890	COG0114	fumarate hydratase activity
SUTMEG_06930	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SUTMEG_06940	COG0424	maF-like protein
SUTMEG_06960	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SUTMEG_06970	COG1114	Component of the transport system for branched-chain amino acids
SUTMEG_06980	COG2814	Major facilitator Superfamily
SUTMEG_07020	COG3604	Transcriptional regulator
SUTMEG_07030	COG3976	FMN-binding domain protein
SUTMEG_07030	COG1053	succinate dehydrogenase
SUTMEG_07050	COG2986	histidine ammonia-lyase
SUTMEG_07070	COG2862	Uncharacterized protein family, UPF0114
SUTMEG_07090	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SUTMEG_07090	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SUTMEG_07100	COG2205	protein histidine kinase activity
SUTMEG_07110	COG0745	RESPONSE REGULATOR receiver
SUTMEG_07140	COG1214	PFAM Peptidase M22, glycoprotease
SUTMEG_07150	COG0456	acetyltransferase
SUTMEG_07180	COG4145	pantothenate transmembrane transporter activity
SUTMEG_07200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SUTMEG_07230	COG0318	PFAM AMP-dependent synthetase and ligase
SUTMEG_07240	COG0484	heat shock protein binding
SUTMEG_07260	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SUTMEG_07270	COG2878	Part of a membrane complex involved in electron transport
SUTMEG_07280	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SUTMEG_07290	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
SUTMEG_07340	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SUTMEG_07340	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SUTMEG_07460	COG1722	exodeoxyribonuclease VII activity
SUTMEG_07470	COG0142	geranyltranstransferase activity
SUTMEG_07480	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SUTMEG_07490	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SUTMEG_07510	COG0728	peptidoglycan biosynthetic process
SUTMEG_07530	COG2249	NAD(P)H dehydrogenase (quinone) activity
SUTMEG_07590	COG0488	(ABC) transporter
SUTMEG_07600	COG2890	protein-(glutamine-N5) methyltransferase activity
SUTMEG_07660	COG3381	protein complex oligomerization
SUTMEG_07680	COG0437	4 iron, 4 sulfur cluster binding
SUTMEG_07710	COG0848	biopolymer transport protein
SUTMEG_07720	COG0811	peptide transport
SUTMEG_07730	COG4771	TonB-dependent receptor
SUTMEG_07740	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SUTMEG_07750	COG4605	iron ion homeostasis
SUTMEG_07760	COG4604	ABC transporter, ATP-binding protein
SUTMEG_07780	COG4607	ABC-type enterochelin transport system periplasmic component
SUTMEG_07790	COG1196	nuclear chromosome segregation
SUTMEG_07810	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SUTMEG_07830	COG0242	peptide deformylase activity
SUTMEG_07850	COG2119	membrane
SUTMEG_07870	COG1309	transcriptional regulator
SUTMEG_07890	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SUTMEG_07910	COG0747	negative chemotaxis
SUTMEG_07930	COG0601	transmembrane transport
SUTMEG_07940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SUTMEG_07960	COG3830	Belongs to the UPF0237 family
SUTMEG_07960	COG0560	Phosphoserine phosphatase
SUTMEG_07980	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
SUTMEG_08010	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SUTMEG_08040	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SUTMEG_08050	COG0024	Methionine aminopeptidase
SUTMEG_08060	COG0052	Belongs to the universal ribosomal protein uS2 family
SUTMEG_08070	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SUTMEG_08090	COG0233	cytoplasmic translational termination
SUTMEG_08120	COG1739	Uncharacterized protein family UPF0029
SUTMEG_08130	COG1408	metallophosphoesterase
SUTMEG_08180	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SUTMEG_08190	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SUTMEG_08230	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SUTMEG_08240	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SUTMEG_08260	COG1979	alcohol dehydrogenase
SUTMEG_08280	COG4191	Histidine kinase
SUTMEG_08300	COG1053	succinate dehydrogenase
SUTMEG_08300	COG0431	NADPH-dependent FMN reductase
SUTMEG_08300	COG3976	FMN-binding domain protein
SUTMEG_08320	COG4191	Histidine kinase
SUTMEG_08340	COG0243	molybdopterin cofactor binding
SUTMEG_08350	COG0437	4 iron, 4 sulfur cluster binding
SUTMEG_08370	COG1115	amino acid carrier protein
SUTMEG_08380	COG0583	DNA-binding transcription factor activity
SUTMEG_08420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SUTMEG_08430	COG1757	Na H antiporter
SUTMEG_08470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SUTMEG_08480	COG0601	transmembrane transport
SUTMEG_08520	COG3069	C4-dicarboxylate transmembrane transporter activity
SUTMEG_08530	COG1473	amidohydrolase
SUTMEG_08550	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SUTMEG_08560	COG0431	NADPH-dependent FMN reductase
SUTMEG_08560	COG1053	succinate dehydrogenase
SUTMEG_08560	COG3976	FMN-binding domain protein
SUTMEG_08570	COG2076	Multidrug Resistance protein
SUTMEG_08630	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SUTMEG_08650	COG0437	4 iron, 4 sulfur cluster binding
SUTMEG_08680	COG0710	3-dehydroquinate dehydratase activity
SUTMEG_08710	COG4566	intracellular signal transduction
SUTMEG_08720	COG1053	succinate dehydrogenase
SUTMEG_08730	COG1053	succinate dehydrogenase
SUTMEG_08750	COG0252	asparaginase activity
SUTMEG_08810	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SUTMEG_08810	COG4651	solute:proton antiporter activity
SUTMEG_08850	COG1053	succinate dehydrogenase
SUTMEG_08900	COG1129	ABC transporter
SUTMEG_08940	COG1129	ABC transporter
SUTMEG_09040	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SUTMEG_09060	COG2205	protein histidine kinase activity
SUTMEG_09070	COG4566	intracellular signal transduction
SUTMEG_09080	COG1053	succinate dehydrogenase
SUTMEG_09090	COG1309	transcriptional regulator
SUTMEG_09100	COG0675	Transposase, IS605 OrfB family
SUTMEG_09200	COG0729	surface antigen
SUTMEG_09220	COG1757	Na H antiporter
SUTMEG_09240	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SUTMEG_09240	COG0047	phosphoribosylformylglycinamidine synthase activity
SUTMEG_09300	COG1353	crispr-associated protein
SUTMEG_09320	COG1337	RAMP superfamily
SUTMEG_09430	COG1957	nucleoside hydrolase
SUTMEG_09440	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SUTMEG_09460	COG1918	ferrous iron import across plasma membrane
SUTMEG_09480	COG0287	Prephenate dehydrogenase
SUTMEG_09480	COG1605	Chorismate mutase
SUTMEG_09490	COG0655	NAD(P)H dehydrogenase (quinone) activity
SUTMEG_09510	COG1053	succinate dehydrogenase
SUTMEG_09550	COG1979	alcohol dehydrogenase
SUTMEG_09560	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SUTMEG_09590	COG1131	(ABC) transporter
SUTMEG_09600	COG0842	Transport permease protein
SUTMEG_09610	COG1053	succinate dehydrogenase
SUTMEG_09630	COG2195	Cleaves the N-terminal amino acid of tripeptides
SUTMEG_09640	COG3069	C4-dicarboxylate transmembrane transporter activity
SUTMEG_09650	COG4191	Histidine kinase
SUTMEG_09660	COG4566	intracellular signal transduction
SUTMEG_09680	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SUTMEG_09720	COG0431	NADPH-dependent FMN reductase
SUTMEG_09720	COG1053	succinate dehydrogenase
SUTMEG_09720	COG3976	FMN-binding domain protein
SUTMEG_09730	COG1053	succinate dehydrogenase
SUTMEG_09730	COG3976	FMN-binding domain protein
SUTMEG_09740	COG4566	intracellular signal transduction
SUTMEG_09760	COG1858	cytochrome C peroxidase
SUTMEG_09770	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SUTMEG_09780	COG1918	ferrous iron import across plasma membrane
SUTMEG_09830	COG0783	Belongs to the Dps family
SUTMEG_09850	COG0583	DNA-binding transcription factor activity
SUTMEG_09890	COG1574	metal-dependent hydrolase with the TIM-barrel fold
SUTMEG_09900	COG0531	amino acid
SUTMEG_09940	COG0789	Transcriptional regulator
SUTMEG_09960	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SUTMEG_10000	COG1295	ribonuclease BN
SUTMEG_10020	COG2205	protein histidine kinase activity
SUTMEG_10020	COG0784	Response regulator, receiver
SUTMEG_10040	COG1459	type II secretion system
SUTMEG_10050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SUTMEG_10060	COG4796	Type ii and iii secretion system protein
SUTMEG_10140	COG3706	GGDEF domain
SUTMEG_10150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SUTMEG_10150	COG2205	protein histidine kinase activity
SUTMEG_10250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SUTMEG_10260	COG2917	probably involved in intracellular septation
SUTMEG_10280	COG0612	Peptidase, M16
SUTMEG_10300	COG1053	succinate dehydrogenase
SUTMEG_10310	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SUTMEG_10310	COG0758	DNA mediated transformation
SUTMEG_10420	COG3976	FMN-binding domain protein
SUTMEG_10420	COG1053	succinate dehydrogenase
SUTMEG_10450	COG3069	C4-dicarboxylate transmembrane transporter activity
SUTMEG_10470	COG2986	histidine ammonia-lyase
SUTMEG_10480	COG0037	tRNA processing
SUTMEG_10510	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SUTMEG_10540	COG1309	transcriptional regulator
SUTMEG_10550	COG1053	succinate dehydrogenase
SUTMEG_10550	COG3976	FMN-binding domain protein
SUTMEG_10560	COG2986	histidine ammonia-lyase
SUTMEG_10570	COG2271	Major facilitator Superfamily
SUTMEG_10620	COG1606	tRNA processing
SUTMEG_10640	COG1691	(AIR) carboxylase
SUTMEG_10650	COG3875	lactate racemase activity
SUTMEG_10680	COG0656	L-ascorbic acid biosynthetic process
SUTMEG_10690	COG1053	succinate dehydrogenase
SUTMEG_10710	COG0642	Histidine kinase
SUTMEG_10710	COG3850	Histidine kinase
SUTMEG_10720	COG0745	RESPONSE REGULATOR receiver
SUTMEG_10760	COG3188	usher protein
SUTMEG_10770	COG3121	Chaperone
SUTMEG_10820	COG1053	succinate dehydrogenase
SUTMEG_10830	COG4566	intracellular signal transduction
SUTMEG_10840	COG1053	succinate dehydrogenase
SUTMEG_10880	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SUTMEG_10930	COG0215	cysteine-tRNA ligase activity
SUTMEG_10940	COG0825	malonyl-CoA metabolic process
SUTMEG_10950	COG2239	Acts as a magnesium transporter
SUTMEG_10980	COG4191	Histidine kinase
SUTMEG_10980	COG2205	protein histidine kinase activity
SUTMEG_10980	COG0745	RESPONSE REGULATOR receiver
SUTMEG_10990	COG4566	intracellular signal transduction
SUTMEG_11000	COG1053	succinate dehydrogenase
SUTMEG_11010	COG1053	succinate dehydrogenase
SUTMEG_11010	COG3976	FMN-binding domain protein
SUTMEG_11020	COG1053	succinate dehydrogenase
SUTMEG_11050	COG0494	nUDIX hydrolase
SUTMEG_11100	COG2205	protein histidine kinase activity
SUTMEG_11100	COG0784	Response regulator, receiver
SUTMEG_11130	COG1283	sodium-dependent phosphate transmembrane transporter activity
SUTMEG_11150	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SUTMEG_11170	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SUTMEG_11200	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SUTMEG_11250	COG0298	carbon dioxide binding
SUTMEG_11280	COG1773	rubredoxin
SUTMEG_11290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SUTMEG_11310	COG0833	amino acid
SUTMEG_11330	COG0842	Transport permease protein
SUTMEG_11340	COG0842	Transport permease protein
SUTMEG_11350	COG1131	(ABC) transporter
SUTMEG_11360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SUTMEG_11420	COG1053	succinate dehydrogenase
SUTMEG_11420	COG3976	FMN-binding domain protein
SUTMEG_11420	COG0431	NADPH-dependent FMN reductase
SUTMEG_11450	COG1970	mechanosensitive ion channel activity
SUTMEG_11460	COG1227	inorganic diphosphatase activity
SUTMEG_11490	COG0437	4 iron, 4 sulfur cluster binding
SUTMEG_11530	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SUTMEG_11550	COG0437	4 iron, 4 sulfur cluster binding
SUTMEG_11570	COG2067	long-chain fatty acid transport protein
SUTMEG_11580	COG0500	methyltransferase
SUTMEG_11610	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SUTMEG_11610	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SUTMEG_11640	COG0302	gtp cyclohydrolase
SUTMEG_11660	COG0602	queuosine metabolic process
SUTMEG_11680	COG1979	alcohol dehydrogenase
SUTMEG_11690	COG0252	asparaginase activity
SUTMEG_11720	COG1288	antiporter activity
SUTMEG_11730	COG2272	Belongs to the type-B carboxylesterase lipase family
SUTMEG_11740	COG2186	Transcriptional regulator
SUTMEG_11830	COG0667	Aldo Keto reductase
SUTMEG_11860	COG0583	DNA-binding transcription factor activity
SUTMEG_11870	COG0251	oxidation-reduction process
SUTMEG_11920	COG1053	succinate dehydrogenase
SUTMEG_11950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SUTMEG_11970	COG1205	dead DEAH box helicase
SUTMEG_11970	COG1111	helicase
SUTMEG_11980	COG0210	DNA helicase
SUTMEG_12010	COG1401	restriction endodeoxyribonuclease activity
SUTMEG_12020	COG4268	DNA restriction-modification system
SUTMEG_12040	COG1473	amidohydrolase
SUTMEG_12060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SUTMEG_12080	COG0326	Molecular chaperone. Has ATPase activity
SUTMEG_12090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SUTMEG_12180	COG4566	intracellular signal transduction
SUTMEG_12200	COG0431	NADPH-dependent FMN reductase
SUTMEG_12200	COG1053	succinate dehydrogenase
SUTMEG_12200	COG3976	FMN-binding domain protein
SUTMEG_12210	COG0583	DNA-binding transcription factor activity
SUTMEG_12230	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SUTMEG_12240	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SUTMEG_12240	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SUTMEG_12260	COG0833	amino acid
SUTMEG_12290	COG0419	ATPase involved in DNA repair
SUTMEG_12330	COG0745	RESPONSE REGULATOR receiver
SUTMEG_12380	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SUTMEG_12410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SUTMEG_12430	COG3976	FMN-binding domain protein
SUTMEG_12430	COG1053	succinate dehydrogenase
SUTMEG_12600	COG1473	amidohydrolase
SUTMEG_12700	COG1028	Short-chain dehydrogenase reductase Sdr
SUTMEG_12710	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SUTMEG_12770	COG0583	DNA-binding transcription factor activity
SUTMEG_12800	COG1053	succinate dehydrogenase
SUTMEG_12800	COG0431	NADPH-dependent FMN reductase
SUTMEG_12800	COG3976	FMN-binding domain protein
SUTMEG_12810	COG1053	succinate dehydrogenase
SUTMEG_12840	COG1053	succinate dehydrogenase
SUTMEG_12850	COG4566	intracellular signal transduction
SUTMEG_12860	COG4191	Histidine kinase
SUTMEG_12870	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SUTMEG_12890	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SUTMEG_12900	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SUTMEG_12920	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SUTMEG_12930	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SUTMEG_12940	COG1053	succinate dehydrogenase
SUTMEG_12940	COG3976	FMN-binding domain protein
SUTMEG_12950	COG1272	protein, Hemolysin III
SUTMEG_12960	COG4566	intracellular signal transduction
SUTMEG_12990	COG0745	RESPONSE REGULATOR receiver
SUTMEG_13010	COG0071	Belongs to the small heat shock protein (HSP20) family
SUTMEG_13020	COG2249	NAD(P)H dehydrogenase (quinone) activity
SUTMEG_13070	COG1309	transcriptional regulator
SUTMEG_13090	COG0765	amino acid transport
SUTMEG_13100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SUTMEG_13110	COG1053	succinate dehydrogenase
SUTMEG_13120	COG0288	reversible hydration of carbon dioxide
SUTMEG_13220	COG1574	metal-dependent hydrolase with the TIM-barrel fold
SUTMEG_13230	COG0531	amino acid
SUTMEG_13240	COG0589	response to stress
SUTMEG_13280	COG1794	racemase activity, acting on amino acids and derivatives
SUTMEG_13320	COG1053	succinate dehydrogenase
SUTMEG_13340	COG0385	Bile acid
SUTMEG_13400	COG3681	Belongs to the UPF0597 family
SUTMEG_13450	COG0531	amino acid
SUTMEG_13460	COG1982	Orn Lys Arg decarboxylase major
SUTMEG_13700	COG3451	type IV secretory pathway VirB4
SUTMEG_13910	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SUTMEG_13930	COG3976	FMN-binding domain protein
SUTMEG_13930	COG1053	succinate dehydrogenase
SUTMEG_13940	COG1053	succinate dehydrogenase
SUTMEG_13960	COG0437	4 iron, 4 sulfur cluster binding
SUTMEG_13970	COG0243	molybdopterin cofactor binding
SUTMEG_14000	COG0243	molybdopterin cofactor binding
SUTMEG_14010	COG0437	4 iron, 4 sulfur cluster binding
SUTMEG_14050	COG3976	FMN-binding domain protein
SUTMEG_14050	COG1053	succinate dehydrogenase
SUTMEG_14060	COG1053	succinate dehydrogenase
SUTMEG_14060	COG3976	FMN-binding domain protein
SUTMEG_14070	COG1053	succinate dehydrogenase
SUTMEG_14100	COG1053	succinate dehydrogenase
SUTMEG_14110	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SUTMEG_14130	COG1053	succinate dehydrogenase
SUTMEG_14130	COG3976	FMN-binding domain protein
SUTMEG_14150	COG1053	succinate dehydrogenase
SUTMEG_14210	COG1053	succinate dehydrogenase
SUTMEG_14240	COG3550	peptidyl-serine autophosphorylation
SUTMEG_14260	COG1598	PFAM Uncharacterised protein family UPF0150
SUTMEG_14320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SUTMEG_14510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SUTMEG_14660	COG1368	sulfuric ester hydrolase activity
SUTMEG_14700	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
SUTMEG_14710	COG0156	8-amino-7-oxononanoate synthase activity
SUTMEG_14730	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SUTMEG_14790	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SUTMEG_14860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SUTMEG_14870	COG0243	molybdopterin cofactor binding
SUTMEG_14880	COG0437	4 iron, 4 sulfur cluster binding
SUTMEG_14990	COG0437	4 iron, 4 sulfur cluster binding
SUTMEG_15000	COG0243	molybdopterin cofactor binding
SUTMEG_15020	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
SUTMEG_15060	COG1401	restriction endodeoxyribonuclease activity
SUTMEG_15080	COG0309	Hydrogenase expression formation protein (HypE)
SUTMEG_15090	COG0409	Hydrogenase expression formation protein
SUTMEG_15110	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SUTMEG_15120	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SUTMEG_15130	COG0375	protein maturation
SUTMEG_15160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SUTMEG_15180	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
SUTMEG_15190	COG3976	FMN-binding domain protein
SUTMEG_15190	COG1053	succinate dehydrogenase
SUTMEG_15200	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SUTMEG_15220	COG1574	metal-dependent hydrolase with the TIM-barrel fold
SUTMEG_15230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SUTMEG_15270	COG3188	usher protein
SUTMEG_15290	COG3121	Chaperone
SUTMEG_15310	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SUTMEG_15330	COG1966	Carbon starvation protein
SUTMEG_15350	COG2807	transmembrane transport
SUTMEG_15390	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SUTMEG_15410	COG4191	Histidine kinase
SUTMEG_15420	COG4566	intracellular signal transduction
SUTMEG_15440	COG1053	succinate dehydrogenase
SUTMEG_15450	COG1982	Orn Lys Arg decarboxylase major
SUTMEG_15490	COG1136	(ABC) transporter
SUTMEG_15520	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SUTMEG_15530	COG0484	heat shock protein binding
SUTMEG_15540	COG4191	Histidine kinase
SUTMEG_15600	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SUTMEG_15610	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SUTMEG_15670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SUTMEG_15680	COG0444	Belongs to the ABC transporter superfamily
SUTMEG_15710	COG0601	transmembrane transport
SUTMEG_15720	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SUTMEG_15730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SUTMEG_15830	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
SUTMEG_15870	COG4133	protoheme IX ABC transporter activity
SUTMEG_15890	COG0322	excinuclease ABC activity
SUTMEG_15900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SUTMEG_15920	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SUTMEG_15970	COG1473	amidohydrolase
SUTMEG_16000	COG0402	S-adenosylhomocysteine deaminase activity
SUTMEG_16010	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SUTMEG_16020	COG0531	amino acid
SUTMEG_16030	COG2197	response regulator
SUTMEG_16040	COG1126	abc transporter atp-binding protein
SUTMEG_16050	COG0765	amino acid transport
SUTMEG_16070	COG3069	C4-dicarboxylate transmembrane transporter activity
SUTMEG_16080	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SUTMEG_16110	COG2198	Histidine kinase
SUTMEG_16110	COG5002	protein histidine kinase activity
SUTMEG_16110	COG0784	Response regulator, receiver
SUTMEG_16120	COG1619	proteins homologs of microcin C7 resistance protein MccF
SUTMEG_16130	COG0590	tRNA wobble adenosine to inosine editing
SUTMEG_16160	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SUTMEG_16170	COG0833	amino acid
SUTMEG_16190	COG2217	Heavy metal translocating P-type atpase
SUTMEG_16200	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SUTMEG_16210	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SUTMEG_16230	COG1473	amidohydrolase
SUTMEG_16240	COG3069	C4-dicarboxylate transmembrane transporter activity
SUTMEG_16310	COG0745	RESPONSE REGULATOR receiver
SUTMEG_16340	COG0833	amino acid
SUTMEG_16360	COG1518	maintenance of DNA repeat elements
SUTMEG_16440	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SUTMEG_16470	COG0583	DNA-binding transcription factor activity
SUTMEG_16500	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SUTMEG_16520	COG0583	DNA-binding transcription factor activity
SUTMEG_16530	COG0039	L-malate dehydrogenase activity
SUTMEG_16590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SUTMEG_16600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SUTMEG_16620	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SUTMEG_16700	COG0656	L-ascorbic acid biosynthetic process
SUTMEG_16710	COG1464	Belongs to the NlpA lipoprotein family
SUTMEG_16730	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SUTMEG_16750	COG4566	intracellular signal transduction
SUTMEG_16770	COG3585	molybdate ion transport
SUTMEG_16790	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
SUTMEG_16810	COG1017	nitric oxide dioxygenase activity
SUTMEG_16810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SUTMEG_16820	COG1959	2 iron, 2 sulfur cluster binding
SUTMEG_16830	COG4566	intracellular signal transduction
SUTMEG_16860	COG0583	DNA-binding transcription factor activity
SUTMEG_16870	COG1053	succinate dehydrogenase
SUTMEG_16910	COG0243	molybdopterin cofactor binding
SUTMEG_16920	COG0437	4 iron, 4 sulfur cluster binding
SUTMEG_16950	COG1053	succinate dehydrogenase
SUTMEG_17110	COG0084	hydrolase, TatD family'
SUTMEG_17130	COG0826	peptidase U32
SUTMEG_17160	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
SUTMEG_17170	COG1115	amino acid carrier protein
SUTMEG_17180	COG2914	Belongs to the UPF0125 (RnfH) family
SUTMEG_17190	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SUTMEG_17220	COG1120	ATPase activity
SUTMEG_17240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SUTMEG_17250	COG0473	3-isopropylmalate dehydrogenase activity
SUTMEG_17280	COG3976	FMN-binding domain protein
SUTMEG_17280	COG1053	succinate dehydrogenase
SUTMEG_17280	COG0431	NADPH-dependent FMN reductase
SUTMEG_17350	COG0583	DNA-binding transcription factor activity
SUTMEG_17400	COG1917	Cupin 2, conserved barrel domain protein
SUTMEG_17400	COG4977	sequence-specific DNA binding
SUTMEG_17410	COG0549	Belongs to the carbamate kinase family
SUTMEG_17430	COG3257	ureidoglycine aminohydrolase activity
SUTMEG_17440	COG1288	antiporter activity
SUTMEG_17500	COG1022	Amp-dependent synthetase and ligase
SUTMEG_17510	COG1022	Amp-dependent synthetase and ligase
SUTMEG_17520	COG0516	GMP reductase activity
SUTMEG_17520	COG0517	IMP dehydrogenase activity
SUTMEG_17530	COG0519	Catalyzes the synthesis of GMP from XMP
SUTMEG_17530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SUTMEG_17610	COG3850	Histidine kinase
SUTMEG_17630	COG0187	DNA topoisomerase II activity
SUTMEG_17640	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SUTMEG_17700	COG0745	RESPONSE REGULATOR receiver
SUTMEG_17710	COG2205	protein histidine kinase activity
SUTMEG_17720	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SUTMEG_17730	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SUTMEG_17740	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SUTMEG_17750	COG1174	glycine betaine transport
SUTMEG_17760	COG1125	glycine betaine transport
SUTMEG_17760	COG0517	IMP dehydrogenase activity
SUTMEG_17770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SUTMEG_17780	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SUTMEG_17810	COG0544	peptidyl-prolyl cis-trans isomerase activity
SUTMEG_17850	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SUTMEG_17880	COG0285	dihydrofolate synthase activity
SUTMEG_17900	COG1473	amidohydrolase
SUTMEG_17910	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SUTMEG_17920	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SUTMEG_17930	COG0101	tRNA pseudouridine synthase activity
SUTMEG_17950	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SUTMEG_17960	COG2116	formate transmembrane transporter activity
SUTMEG_17990	COG0564	pseudouridine synthase activity
SUTMEG_18020	COG0123	including yeast histone deacetylase and acetoin utilization protein
SUTMEG_18030	COG2951	lytic endotransglycosylase activity
SUTMEG_18040	COG0697	spore germination
SUTMEG_18050	COG0179	Fumarylacetoacetate (FAA) hydrolase
SUTMEG_18060	COG1183	phosphatidylcholine synthase activity
SUTMEG_18100	COG0733	neurotransmitter:sodium symporter activity
SUTMEG_18110	COG0733	neurotransmitter:sodium symporter activity
SUTMEG_18120	COG0733	neurotransmitter:sodium symporter activity
SUTMEG_18130	COG0733	neurotransmitter:sodium symporter activity
SUTMEG_18140	COG1280	lysine exporter protein (LysE YggA)
SUTMEG_18170	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SUTMEG_18180	COG1199	ATP-dependent helicase activity
SUTMEG_18220	COG3069	C4-dicarboxylate transmembrane transporter activity
SUTMEG_18280	COG3842	ATPase activity
SUTMEG_18340	COG1053	succinate dehydrogenase
SUTMEG_18340	COG3976	FMN-binding domain protein
SUTMEG_18340	COG0431	NADPH-dependent FMN reductase
SUTMEG_18370	COG0039	L-malate dehydrogenase activity
SUTMEG_18380	COG1253	flavin adenine dinucleotide binding
SUTMEG_18400	COG0737	Belongs to the 5'-nucleotidase family
SUTMEG_18410	COG1115	amino acid carrier protein
SUTMEG_18430	COG1322	Protein conserved in bacteria
SUTMEG_18440	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SUTMEG_18440	COG4651	solute:proton antiporter activity
SUTMEG_18480	COG1129	ABC transporter
SUTMEG_18490	COG0494	nUDIX hydrolase
SUTMEG_18500	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SUTMEG_18500	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SUTMEG_18530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SUTMEG_18540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SUTMEG_18550	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SUTMEG_18590	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
SUTMEG_18600	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SUTMEG_18610	COG3842	ATPase activity
SUTMEG_18620	COG1176	ABC-type spermidine putrescine transport system, permease component I
SUTMEG_18640	COG1840	ABC-type Fe3 transport system, periplasmic component
SUTMEG_18660	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SUTMEG_18670	COG1966	Carbon starvation protein
SUTMEG_18700	COG1846	Transcriptional regulator
SUTMEG_18710	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SUTMEG_18720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SUTMEG_18730	COG0765	amino acid transport
SUTMEG_18740	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SUTMEG_18750	COG1185	polyribonucleotide nucleotidyltransferase activity
SUTMEG_18760	COG0149	triose-phosphate isomerase activity
SUTMEG_18830	COG1472	Belongs to the glycosyl hydrolase 3 family
SUTMEG_18840	COG1381	Involved in DNA repair and RecF pathway recombination
SUTMEG_18850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SUTMEG_18860	COG0571	ribonuclease III activity
SUTMEG_18880	COG0481	GTPase activity
SUTMEG_18900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SUTMEG_18910	COG1028	Short-chain dehydrogenase reductase Sdr
SUTMEG_18920	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SUTMEG_18930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SUTMEG_18940	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SUTMEG_18950	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
SUTMEG_18960	COG1027	Aspartate ammonia-lyase
SUTMEG_18970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SUTMEG_18980	COG1053	succinate dehydrogenase
SUTMEG_19020	COG0628	permease
SUTMEG_19030	COG3069	C4-dicarboxylate transmembrane transporter activity
SUTMEG_19040	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
SUTMEG_19060	COG1162	GTPase activity
SUTMEG_19070	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SUTMEG_19080	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SUTMEG_19110	COG0542	response to heat
SUTMEG_19130	COG0314	molybdopterin synthase activity
SUTMEG_19140	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
SUTMEG_19150	COG0303	'Molybdopterin
SUTMEG_19160	COG1763	Mo-molybdopterin cofactor biosynthetic process
SUTMEG_19190	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SUTMEG_19210	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SUTMEG_19220	COG1074	ATP-dependent DNA helicase activity
SUTMEG_19230	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
SUTMEG_19260	COG0305	Participates in initiation and elongation during chromosome replication
SUTMEG_19270	COG0359	binds to the 23S rRNA
SUTMEG_19280	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SUTMEG_19310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SUTMEG_19320	COG0557	exoribonuclease II activity
SUTMEG_19340	COG0583	DNA-binding transcription factor activity
SUTMEG_19360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SUTMEG_19370	COG1397	ADP-ribosylglycohydrolase
SUTMEG_19390	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
SUTMEG_19390	COG3264	Mechanosensitive ion channel
SUTMEG_19400	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
SUTMEG_19410	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SUTMEG_19430	COG0330	HflC and HflK could
SUTMEG_19440	COG0330	HflC and HflK could
SUTMEG_19450	COG3366	ferrous iron transmembrane transporter activity
SUTMEG_19460	COG0700	Nucleoside recognition
SUTMEG_19480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SUTMEG_19490	COG2223	nitrite transmembrane transporter activity
SUTMEG_19500	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SUTMEG_19510	COG1923	regulation of RNA biosynthetic process
SUTMEG_19530	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SUTMEG_19540	COG2976	Protein conserved in bacteria
SUTMEG_19560	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SUTMEG_19570	COG1426	Protein conserved in bacteria
SUTMEG_19590	COG0105	UTP biosynthetic process
SUTMEG_19630	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SUTMEG_19640	COG1473	amidohydrolase
SUTMEG_19660	COG5002	protein histidine kinase activity
SUTMEG_19690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SUTMEG_19700	COG0581	inorganic phosphate transmembrane transporter activity
SUTMEG_19710	COG0573	inorganic phosphate transmembrane transporter activity
SUTMEG_19730	COG0776	regulation of translation
SUTMEG_19740	COG0072	phenylalanine-tRNA ligase activity
SUTMEG_19740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SUTMEG_19750	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SUTMEG_19760	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SUTMEG_19770	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SUTMEG_19780	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SUTMEG_19790	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SUTMEG_19800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SUTMEG_19860	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SUTMEG_19870	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SUTMEG_19880	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SUTMEG_19900	COG2975	iron-sulfur cluster assembly
SUTMEG_19910	COG0633	Ferredoxin
SUTMEG_19930	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
SUTMEG_19940	COG0316	Belongs to the HesB IscA family
SUTMEG_19950	COG0822	iron-sulfur transferase activity
SUTMEG_19960	COG1104	cysteine desulfurase activity
SUTMEG_19970	COG1959	2 iron, 2 sulfur cluster binding
SUTMEG_19980	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SUTMEG_20000	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
SUTMEG_20010	COG0746	molybdenum cofactor guanylyltransferase activity
SUTMEG_20020	COG0303	'Molybdopterin
SUTMEG_20030	COG2129	metallophosphoesterase
SUTMEG_20050	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
SUTMEG_20060	COG1674	ftsk spoiiie
SUTMEG_20070	COG0492	ferredoxin-NADP+ reductase activity
SUTMEG_20090	COG0347	Belongs to the P(II) protein family
SUTMEG_20110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SUTMEG_20120	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SUTMEG_20130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SUTMEG_20140	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
SUTMEG_20150	COG1534	Rna-binding protein
SUTMEG_20160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SUTMEG_20170	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SUTMEG_20180	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SUTMEG_20200	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SUTMEG_20220	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SUTMEG_20250	COG3118	belongs to the thioredoxin family
SUTMEG_20260	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SUTMEG_20290	COG0181	hydroxymethylbilane synthase activity
SUTMEG_20300	COG0254	rRNA binding
SUTMEG_20320	COG0534	Mate efflux family protein
SUTMEG_20330	COG0501	Belongs to the peptidase M48B family
SUTMEG_20350	COG0776	regulation of translation
SUTMEG_20370	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SUTMEG_20380	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SUTMEG_20400	COG0402	S-adenosylhomocysteine deaminase activity
SUTMEG_20410	COG2885	chlorophyll binding
SUTMEG_20410	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
SUTMEG_20430	COG0826	peptidase U32
SUTMEG_20450	COG0802	atpase or kinase
SUTMEG_20460	COG0860	N-Acetylmuramoyl-L-alanine amidase
SUTMEG_20490	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SUTMEG_20500	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SUTMEG_20510	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SUTMEG_20520	COG0009	L-threonylcarbamoyladenylate synthase
SUTMEG_20540	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SUTMEG_20590	COG2204	response regulator
SUTMEG_20670	COG0308	aminopeptidase N
SUTMEG_20680	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
SUTMEG_20760	COG0424	maF-like protein
SUTMEG_20770	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SUTMEG_20780	COG0799	negative regulation of ribosome biogenesis
SUTMEG_20790	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SUTMEG_20810	COG0151	Belongs to the GarS family
SUTMEG_20820	COG0217	transcriptional regulatory protein
SUTMEG_20830	COG1473	amidohydrolase
SUTMEG_20850	COG2197	response regulator
SUTMEG_20860	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
SUTMEG_20870	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SUTMEG_20870	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SUTMEG_20900	COG0484	heat shock protein binding
SUTMEG_20920	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SUTMEG_20930	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SUTMEG_20940	COG0429	hydrolase of the alpha beta-hydrolase fold
SUTMEG_20950	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SUTMEG_20970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SUTMEG_20980	COG0312	modulator of DNA gyrase
SUTMEG_21010	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SUTMEG_21030	COG0318	PFAM AMP-dependent synthetase and ligase
SUTMEG_21050	COG2186	Transcriptional regulator
SUTMEG_21070	COG1380	Effector of murein hydrolase LrgA
SUTMEG_21080	COG1346	cytolysis
SUTMEG_21090	COG0471	metal ion transport
SUTMEG_21100	COG2070	2-Nitropropane dioxygenase
SUTMEG_21110	COG0482	sulfurtransferase activity
SUTMEG_21120	COG0861	Integral membrane protein TerC family