locus-tag	class	description
syc0001_c	COG0716	FMN binding
syc0004_d	COG1487	ribonuclease activity
syc0005_d	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
syc0007_d	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
syc0008_d	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
syc0010_c	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
syc0011_d	COG0613	PHP domain protein
syc0012_c	COG0740	serine-type endopeptidase activity
syc0015_c	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
syc0017_d	COG0110	maltose O-acetyltransferase activity
syc0020_c	COG1397	ADP-ribosylglycohydrolase
syc0024_d	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
syc0027_c	COG2217	Heavy metal translocating P-type atpase
syc0033_d	COG0038	chloride channel
syc0034_c	COG0018	arginyl-trna synthetase
syc0035_c	COG0805	protein transport
syc0039_c	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
syc0041_c	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
syc0043_d	COG5002	protein histidine kinase activity
syc0045_c	COG0038	chloride channel
syc0048_c	COG0539	negative regulation of cytoplasmic translation
syc0050_d	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
syc0051_d	COG5322	oxidoreductase activity
syc0052_d	COG0825	malonyl-CoA metabolic process
syc0053_d	COG0300	oxidoreductase activity
syc0054_d	COG0302	gtp cyclohydrolase
syc0055_d	COG0384	phenazine biosynthesis protein PhzF
syc0056_d	COG2385	sporulation resulting in formation of a cellular spore
syc0059_d	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
syc0063_d	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
syc0064_c	COG3659	wide pore channel activity
syc0065_d	COG0662	Cupin 2, conserved barrel domain protein
syc0065_d	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
syc0066_d	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
syc0067_c	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
syc0069_c	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
syc0071_d	COG0230	Belongs to the bacterial ribosomal protein bL34 family
syc0072_d	COG0594	ribonuclease P activity
syc0074_d	COG0706	membrane insertase activity
syc0078_d	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
syc0079_c	COG1032	radical SAM domain protein
syc0080_d	COG0826	peptidase U32
syc0089_d	COG2010	Cytochrome c
syc0094_c	COG3659	wide pore channel activity
syc0095_d	COG3487	Iron-regulated protein
syc0098_d	COG1214	PFAM Peptidase M22, glycoprotease
syc0101_c	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
syc0102_c	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
syc0103_c	COG0416	fatty acid biosynthetic process
syc0104_c	COG0745	RESPONSE REGULATOR receiver
syc0105_d	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
syc0107_c	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
syc0108_d	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
syc0109_c	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
syc0110_c	COG0288	reversible hydration of carbon dioxide
syc0113_c	COG0191	fructose-bisphosphate aldolase activity
syc0115_d	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
syc0116_d	COG0083	homoserine kinase activity
syc0117_d	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
syc0121_d	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
syc0123_c	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
syc0124_d	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
syc0124_d	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
syc0125_c	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
syc0128_c	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
syc0129_c	COG4451	ribulose bisphosphate carboxylase, small
syc0130_c	COG1850	ribulose-bisphosphate carboxylase activity
syc0131_c	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
syc0133_c	COG4451	ribulose bisphosphate carboxylase, small
syc0133_c	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
syc0134_c	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
syc0136_c	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
syc0137_c	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
syc0139_c	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
syc0140_d	COG1007	ATP synthesis coupled electron transport
syc0141_d	COG1136	(ABC) transporter
syc0142_c	COG0730	response to heat
syc0144_d	COG0095	Lipoate-protein ligase
syc0146_c	COG1840	ABC-type Fe3 transport system, periplasmic component
syc0147_c	COG4106	trans-aconitate 2-methyltransferase activity
syc0148_c	COG1178	ABC-type Fe3 transport system permease component
syc0149_d	COG3842	ATPase activity
syc0152_d	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
syc0162_c	COG0123	including yeast histone deacetylase and acetoin utilization protein
syc0163_d	COG0737	Belongs to the 5'-nucleotidase family
syc0165_d	COG0537	adenosine 5'-monophosphoramidase activity
syc0167_c	COG3338	carbonate dehydratase activity
syc0168_c	COG1606	tRNA processing
syc0169_d	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
syc0172_d	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
syc0175_c	COG0488	(ABC) transporter
syc0177_c	COG0439	Biotin carboxylase
syc0178_d	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
syc0179_c	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
syc0182_d	COG0564	pseudouridine synthase activity
syc0184_c	COG1410	methionine synthase
syc0184_c	COG0646	methionine synthase
syc0185_d	COG0598	Magnesium transport protein CorA
syc0186_c	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
syc0188_c	COG2124	cytochrome p450
syc0189_d	COG1575	Belongs to the MenA family. Type 1 subfamily
syc0190_d	COG2095	MarC family integral membrane protein
syc0194_c	COG1316	TRANSCRIPTIONal
syc0195_d	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
syc0196_d	COG4279	zinc finger
syc0198_d	COG4251	negative regulation of phosphorylation
syc0199_d	COG0784	Response regulator, receiver
syc0203_c	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
syc0204_d	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
syc0206_d	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
syc0207_c	COG0713	ATP synthesis coupled electron transport
syc0208_c	COG0839	Belongs to the complex I subunit 6 family
syc0209_c	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
syc0210_c	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
syc0212_c	COG0628	permease
syc0213_d	COG0242	peptide deformylase activity
syc0221_c	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
syc0222_c	COG0602	queuosine metabolic process
syc0224_c	COG2226	methyltransferase
syc0227_c	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
syc0228_c	COG0305	Participates in initiation and elongation during chromosome replication
syc0228_c	COG1372	Participates in initiation and elongation during chromosome replication
syc0228_c	COG0305	Participates in initiation and elongation during chromosome replication
syc0228_c	COG1372	Participates in initiation and elongation during chromosome replication
syc0229_d	COG4581	dead DEAH box helicase
syc0230_c	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
syc0234_c	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
syc0235_c	COG1108	ABC-type Mn2 Zn2 transport systems permease components
syc0236_c	COG1121	(ABC) transporter
syc0237_d	COG0803	Belongs to the bacterial solute-binding protein 9 family
syc0238_d	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
syc0239_d	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
syc0240_c	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
syc0241_d	COG1132	(ABC) transporter
syc0243_c	COG0583	DNA-binding transcription factor activity
syc0244_c	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
syc0244_c	COG0646	methionine synthase
syc0245_c	COG0180	Tryptophanyl-tRNA synthetase
syc0251_c	COG0589	response to stress
syc0252_c	COG0514	ATP-dependent DNA helicase (RecQ)
syc0253_c	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
syc0254_d	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
syc0255_c	COG3706	GGDEF domain
syc0259_c	COG0515	serine threonine protein kinase
syc0259_c	COG1357	PFAM Pentapeptide repeats (8 copies)
syc0260_d	COG0072	phenylalanine-tRNA ligase activity
syc0260_d	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
syc0261_d	COG0358	DNA primase activity
syc0262_c	COG0640	Transcriptional regulator
syc0267_c	COG0303	'Molybdopterin
syc0268_d	COG0315	cyclic pyranopterin monophosphate synthase activity
syc0268_d	COG0521	Mo-molybdopterin cofactor biosynthetic process
syc0270_d	COG0314	molybdopterin synthase activity
syc0271_d	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
syc0274_d	COG0291	Belongs to the bacterial ribosomal protein bL35 family
syc0275_d	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
syc0276_d	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
syc0279_c	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
syc0279_c	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
syc0282_c	COG2239	Acts as a magnesium transporter
syc0283_d	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
syc0285_d	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
syc0287_c	COG0025	NhaP-type Na H and K H
syc0288_d	COG0116	Belongs to the methyltransferase superfamily
syc0289_d	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
syc0291_c	COG0501	Belongs to the peptidase M48B family
syc0292_c	COG0003	Pfam Anion-transporting ATPase
syc0294_c	COG0038	chloride channel
syc0295_c	COG0625	glutathione transferase activity
syc0296_d	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
syc0298_c	COG0420	3'-5' exonuclease activity
syc0299_c	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
syc0308_c	COG0583	DNA-binding transcription factor activity
syc0310_d	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
syc0311_d	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
syc0312_d	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
syc0313_d	COG1116	anion transmembrane transporter activity
syc0313_d	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
syc0314_d	COG1116	anion transmembrane transporter activity
syc0315_d	COG0243	molybdopterin cofactor binding
syc0318_d	COG0723	plastoquinol--plastocyanin reductase activity
syc0319_d	COG0739	heme binding
syc0320_d	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
syc0321_d	COG2875	Belongs to the precorrin methyltransferase family
syc0324_c	COG0612	Peptidase, M16
syc0326_d	COG1566	PFAM secretion protein HlyD family protein
syc0328_c	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
syc0330_c	COG0211	Belongs to the bacterial ribosomal protein bL27 family
syc0331_c	COG0261	This protein binds to 23S rRNA in the presence of protein L20
syc0333_d	COG4251	negative regulation of phosphorylation
syc0334_d	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
syc0336_c	COG0386	Belongs to the glutathione peroxidase family
syc0343_d	COG4115	mRNA cleavage
syc0345_c	COG4974	Belongs to the 'phage' integrase family
syc0349_d	COG2226	methyltransferase
syc0351_d	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
syc0352_d	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
syc0353_d	COG0134	indole-3-glycerol-phosphate synthase activity
syc0356_c	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
syc0359_c	COG0194	GDP metabolic process
syc0360_d	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
syc0361_d	COG0746	molybdenum cofactor guanylyltransferase activity
syc0368_c	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
syc0369_c	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
syc0370_c	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
syc0372_d	COG4447	cellulose binding
syc0378_d	COG0815	Transfers the fatty acyl group on membrane lipoproteins
syc0379_d	COG3046	protein related to deoxyribodipyrimidine photolyase
syc0380_d	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
syc0382_d	COG1691	(AIR) carboxylase
syc0392_d	COG5001	Diguanylate cyclase
syc0393_c	COG1074	ATP-dependent DNA helicase activity
syc0396_d	COG1116	anion transmembrane transporter activity
syc0397_d	COG1160	GTP binding
syc0398_d	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
syc0399_d	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
syc0399_d	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
syc0401_d	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
syc0404_d	COG0271	Belongs to the BolA IbaG family
syc0405_d	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
syc0408_c	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
syc0412_c	COG0037	tRNA processing
syc0417_d	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
syc0422_c	COG0312	modulator of DNA gyrase
syc0425_c	COG0557	exoribonuclease II activity
syc0426_c	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
syc0427_c	COG0267	Belongs to the bacterial ribosomal protein bL33 family
syc0428_d	COG3266	domain, Protein
syc0428_d	COG0515	serine threonine protein kinase
syc0430_d	COG0398	Pfam SNARE associated Golgi protein
syc0433_c	COG0126	phosphoglycerate kinase activity
syc0434_d	COG0589	response to stress
syc0436_d	COG0628	permease
syc0437_d	COG0564	pseudouridine synthase activity
syc0438_d	COG4991	sh3 domain protein
syc0438_d	COG0515	serine threonine protein kinase
syc0438_d	COG3064	Membrane
syc0440_c	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
syc0441_c	COG0776	regulation of translation
syc0444_d	COG0489	protein tyrosine kinase activity
syc0445_d	COG0772	Belongs to the SEDS family
syc0446_d	COG0363	glucosamine-6-phosphate deaminase activity
syc0448_c	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
syc0449_d	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
syc0450_d	COG2226	methyltransferase
syc0451_d	COG4399	Belongs to the UPF0754 family
syc0453_d	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
syc0456_d	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
syc0460_c	COG0542	response to heat
syc0461_c	COG3794	PFAM blue (type 1) copper domain protein
syc0463_c	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
syc0464_c	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
syc0466_c	COG1215	transferase activity, transferring glycosyl groups
syc0467_c	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
syc0468_c	COG0569	domain protein
syc0469_c	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
syc0470_c	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
syc0476_c	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
syc0481_c	COG0508	dehydrogenase complex catalyzes the overall conversion of
syc0488_c	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
syc0491_c	COG0352	thiamine-phosphate diphosphorylase activity
syc0493_c	COG1413	lyase activity
syc0494_c	COG1413	lyase activity
syc0497_c	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
syc0498_c	COG0237	dephospho-CoA kinase activity
syc0499_c	COG0237	dephospho-CoA kinase activity
syc0503_d	COG2385	sporulation resulting in formation of a cellular spore
syc0505_d	COG0170	dolichyl monophosphate biosynthetic process
syc0510_c	COG1166	arginine decarboxylase activity
syc0515_c	COG2308	Evidence 4 Homologs of previously reported genes of
syc0516_c	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
syc0517_c	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
syc0518_d	COG0596	Alpha beta hydrolase
syc0519_c	COG2052	Domain of unknown function (DUF370)
syc0525_c	COG0318	PFAM AMP-dependent synthetase and ligase
syc0526_c	COG4948	Mandelate Racemase Muconate Lactonizing
syc0527_c	COG1640	4-alpha-glucanotransferase
syc0529_d	COG0217	transcriptional regulatory protein
syc0531_d	COG0840	transmembrane signaling receptor activity
syc0533_d	COG0745	RESPONSE REGULATOR receiver
syc0534_d	COG5002	protein histidine kinase activity
syc0535_d	COG1187	pseudouridine synthase activity
syc0537_d	COG0788	formyltetrahydrofolate deformylase activity
syc0538_d	COG0114	fumarate hydratase activity
syc0540_c	COG1011	Hydrolase
syc0542_c	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
syc0546_c	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
syc0547_d	COG0333	Belongs to the bacterial ribosomal protein bL32 family
syc0548_c	COG0572	uridine kinase
syc0551_d	COG1160	GTP binding
syc0557_d	COG0735	belongs to the Fur family
syc0559_c	COG2814	Major facilitator Superfamily
syc0560_c	COG1381	Involved in DNA repair and RecF pathway recombination
syc0561_c	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
syc0564_d	COG1280	lysine exporter protein (LysE YggA)
syc0566_c	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
syc0567_d	COG0572	uridine kinase
syc0568_c	COG0617	tRNA 3'-terminal CCA addition
syc0569_d	COG0275	rRNA processing
syc0570_d	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
syc0571_c	COG0251	oxidation-reduction process
syc0574_d	COG0412	Dienelactone hydrolase
syc0575_c	COG0181	hydroxymethylbilane synthase activity
syc0577_c	COG0483	inositol monophosphate 1-phosphatase activity
syc0580_d	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
syc0580_d	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
syc0581_c	COG1316	TRANSCRIPTIONal
syc0583_d	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
syc0584_d	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
syc0586_c	COG0523	cobalamin synthesis protein
syc0588_d	COG0354	folic acid binding
syc0591_c	COG0157	Belongs to the NadC ModD family
syc0592_d	COG1653	transport
syc0596_c	COG1231	oxidoreductase activity
syc0598_c	COG0285	dihydrofolate synthase activity
syc0599_c	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
syc0600_d	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
syc0601_d	COG0488	(ABC) transporter
syc0603_c	COG0529	Catalyzes the synthesis of activated sulfate
syc0605_d	COG3453	Protein conserved in bacteria
syc0605_d	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
syc0606_d	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
syc0608_c	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
syc0612_c	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
syc0614_c	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
syc0615_c	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
syc0617_d	COG0151	Belongs to the GarS family
syc0618_d	COG5002	protein histidine kinase activity
syc0619_d	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
syc0620_d	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
syc0624_c	COG1022	Amp-dependent synthetase and ligase
syc0625_d	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
syc0627_d	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
syc0630_c	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
syc0633_c	COG0316	Belongs to the HesB IscA family
syc0637_d	COG1049	propionate catabolic process, 2-methylcitrate cycle
syc0642_c	COG3411	Ferredoxin
syc0643_c	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
syc0644_c	COG2894	cell division
syc0646_d	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
syc0648_d	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
syc0650_c	COG0070	glutamate synthase
syc0650_c	COG0067	glutamate synthase
syc0650_c	COG0069	glutamate synthase activity
syc0653_d	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
syc0654_d	COG0049	tRNA binding
syc0655_d	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
syc0656_d	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
syc0657_d	COG0051	transcription antitermination factor activity, RNA binding
syc0659_c	COG0077	Prephenate dehydratase
syc0661_c	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
syc0662_c	COG1530	ribonuclease E activity
syc0663_c	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
syc0664_c	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
syc0666_d	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
syc0672_c	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
syc0675_c	COG1666	GTP binding
syc0677_c	COG0857	belongs to the CobB CobQ family
syc0679_d	COG0300	oxidoreductase activity
syc0679_d	COG3000	fatty acid hydroxylase
syc0681_c	COG0643	Histidine kinase
syc0681_c	COG2198	Histidine kinase
syc0681_c	COG0643	Histidine kinase
syc0681_c	COG2198	Histidine kinase
syc0682_c	COG0840	transmembrane signaling receptor activity
syc0682_c	COG2203	Gaf domain
syc0685_c	COG0784	Response regulator, receiver
syc0687_c	COG0436	Aminotransferase
syc0689_c	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
syc0692_d	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
syc0693_d	COG2805	Type II/IV secretion system protein
syc0698_d	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
syc0699_c	COG2072	flavoprotein involved in K transport
syc0704_d	COG2144	transferase activity, transferring acyl groups
syc0705_c	COG2255	four-way junction helicase activity
syc0710_c	COG0017	Asparaginyl-tRNA synthetase
syc0715_c	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
syc0715_c	COG0392	lysyltransferase activity
syc0716_c	COG0628	permease
syc0718_c	COG4166	transmembrane transport
syc0720_c	COG0047	phosphoribosylformylglycinamidine synthase activity
syc0721_c	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
syc0722_d	COG0735	belongs to the Fur family
syc0723_d	COG3300	MHYT domain
syc0723_d	COG5001	Diguanylate cyclase
syc0725_c	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
syc0726_c	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
syc0727_c	COG0484	heat shock protein binding
syc0730_d	COG0438	transferase activity, transferring glycosyl groups
syc0732_c	COG1385	rRNA (uridine-N3-)-methyltransferase activity
syc0737_c	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
syc0740_d	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
syc0743_d	COG1842	Phage shock protein A
syc0749_d	COG0625	glutathione transferase activity
syc0754_d	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
syc0755_d	COG1132	(ABC) transporter
syc0756_d	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
syc0756_d	COG0574	Belongs to the PEP-utilizing enzyme family
syc0757_d	COG1357	PFAM Pentapeptide repeats (8 copies)
syc0757_d	COG0515	serine threonine protein kinase
syc0758_c	COG1480	7TM receptor with intracellular HD hydrolase
syc0759_d	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
syc0760_d	COG0142	geranyltranstransferase activity
syc0763_d	COG0454	-acetyltransferase
syc0766_c	COG0737	Belongs to the 5'-nucleotidase family
syc0767_c	COG2319	Wd-40 repeat
syc0806_c	COG1061	Type III restriction enzyme res subunit
syc0814_c	COG0582	viral genome integration into host DNA
syc0817_d	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
syc0818_d	COG0793	Belongs to the peptidase S41A family
syc0819_c	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
syc0822_c	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
syc0823_d	COG1982	Orn Lys Arg decarboxylase major
syc0827_c	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
syc0827_c	COG0758	DNA mediated transformation
syc0829_c	COG0824	Thioesterase
syc0830_d	COG0589	response to stress
syc0835_d	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
syc0836_d	COG0539	negative regulation of cytoplasmic translation
syc0839_d	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
syc0841_c	COG0640	Transcriptional regulator
syc0843_c	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
syc0844_c	COG0459	protein refolding
syc0845_c	COG1028	Short-chain dehydrogenase reductase Sdr
syc0846_c	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
syc0848_d	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
syc0850_c	COG0724	RNA recognition motif
syc0855_c	COG0408	coproporphyrinogen oxidase activity
syc0857_c	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
syc0859_c	COG0540	Belongs to the ATCase OTCase family
syc0860_c	COG2094	Belongs to the DNA glycosylase MPG family
syc0863_d	COG1402	creatininase
syc0864_c	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
syc0864_c	COG3264	Mechanosensitive ion channel
syc0868_c	COG0287	Prephenate dehydrogenase
syc0875_d	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
syc0877_c	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
syc0879_d	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
syc0880_c	COG1376	ErfK ybiS ycfS ynhG family protein
syc0881_c	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
syc0882_c	COG2205	protein histidine kinase activity
syc0882_c	COG2202	Pas domain
syc0883_d	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
syc0884_d	COG1053	succinate dehydrogenase
syc0885_c	COG1132	(ABC) transporter
syc0886_c	COG0148	phosphopyruvate hydratase activity
syc0887_d	COG0346	lactoylglutathione lyase activity
syc0888_d	COG0542	response to heat
syc0889_d	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
syc0890_d	COG0250	Participates in transcription elongation, termination and antitermination
syc0891_d	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
syc0892_d	COG0081	regulation of translation
syc0893_d	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
syc0894_d	COG0222	ribosome binding
syc0896_c	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
syc0898_c	COG0129	dihydroxy-acid dehydratase activity
syc0899_c	COG3854	ATPases associated with a variety of cellular activities
syc0901_c	COG0492	ferredoxin-NADP+ reductase activity
syc0902_c	COG4178	(ABC) transporter
syc0905_c	COG0586	Pfam SNARE associated Golgi protein
syc0906_c	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
syc0908_c	COG1420	regulation of RNA biosynthetic process
syc0911_d	COG2062	phosphohistidine phosphatase, SixA
syc0912_d	COG0372	Belongs to the citrate synthase family
syc0913_c	COG1193	negative regulation of DNA recombination
syc0914_c	COG0668	transmembrane transport
syc0915_c	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
syc0916_c	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
syc0918_d	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
syc0919_d	COG3781	membrane
syc0920_c	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
syc0921_d	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
syc0923_d	COG0515	serine threonine protein kinase
syc0927_c	COG2226	methyltransferase
syc0931_d	COG0205	6-phosphofructokinase activity
syc0932_c	COG2119	membrane
syc0935_d	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
syc0936_c	COG0525	valine-tRNA ligase activity
syc0937_d	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
syc0938_d	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
syc0939_d	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
syc0940_c	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
syc0941_d	COG0429	hydrolase of the alpha beta-hydrolase fold
syc0947_c	COG2022	thiamine diphosphate biosynthetic process
syc0951_d	COG2211	Major facilitator Superfamily
syc0952_d	COG0587	DNA-directed DNA polymerase activity
syc0953_d	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
syc0954_d	COG0402	S-adenosylhomocysteine deaminase activity
syc0955_d	COG0277	FAD linked oxidase domain protein
syc0958_c	COG1136	(ABC) transporter
syc0959_d	COG0556	nucleotide-excision repair
syc0962_d	COG1122	ATPase activity
syc0963_d	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
syc0965_d	COG0745	RESPONSE REGULATOR receiver
syc0967_c	COG0012	GTP binding
syc0968_d	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
syc0972_c	COG0861	Integral membrane protein TerC family
syc0975_c	COG0475	glutathione-regulated potassium exporter activity
syc0979_c	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
syc0983_c	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
syc0984_c	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
syc0985_c	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
syc0986_d	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
syc0987_d	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
syc0991_c	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
syc0992_c	COG0363	glucosamine-6-phosphate deaminase activity
syc0995_c	COG1175	transmembrane transport
syc0996_d	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
syc1002_c	COG0628	permease
syc1003_d	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
syc1003_d	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
syc1004_d	COG0793	Belongs to the peptidase S41A family
syc1009_d	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
syc1012_c	COG0644	oxidoreductase
syc1013_c	COG0233	cytoplasmic translational termination
syc1014_c	COG0528	UMP kinase activity
syc1015_d	COG1494	fructose-1,6-bisphosphatase
syc1016_d	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
syc1019_d	COG0702	epimerase
syc1022_c	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
syc1028_d	COG0196	riboflavin kinase activity
syc1029_c	COG3300	MHYT domain
syc1029_c	COG5001	Diguanylate cyclase
syc1030_d	COG1012	belongs to the aldehyde dehydrogenase family
syc1031_c	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
syc1033_c	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
syc1034_c	COG0406	alpha-ribazole phosphatase activity
syc1037_d	COG0768	penicillin binding
syc1038_c	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
syc1039_c	COG5002	protein histidine kinase activity
syc1039_c	COG2205	protein histidine kinase activity
syc1039_c	COG0784	Response regulator, receiver
syc1040_d	COG0481	GTPase activity
syc1041_d	COG0681	Belongs to the peptidase S26 family
syc1042_d	COG0762	integral membrane protein
syc1043_c	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
syc1045_c	COG1902	pentaerythritol trinitrate reductase activity
syc1046_c	COG1722	exodeoxyribonuclease VII activity
syc1047_c	COG0395	ABC-type sugar transport system, permease component
syc1049_d	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
syc1054_d	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
syc1055_d	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
syc1058_d	COG0456	acetyltransferase
syc1059_d	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
syc1063_c	COG0343	queuine tRNA-ribosyltransferase activity
syc1064_d	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
syc1065_c	COG2205	protein histidine kinase activity
syc1068_d	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
syc1069_d	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
syc1070_d	COG0750	zinc metalloprotease
syc1071_d	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
syc1072_d	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
syc1073_d	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
syc1076_c	COG0004	ammonium transporteR
syc1077_c	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
syc1078_d	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
syc1079_d	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
syc1081_c	COG1403	HNH endonuclease
syc1083_c	COG0701	Predicted permease
syc1085_c	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
syc1087_c	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
syc1089_d	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
syc1090_d	COG1131	(ABC) transporter
syc1096_d	COG3788	relative of glutathione S-transferase, MAPEG superfamily
syc1098_d	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
syc1106_d	COG0159	tryptophan synthase activity
syc1108_c	COG0135	phosphoribosylanthranilate isomerase activity
syc1112_d	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
syc1113_d	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
syc1114_d	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
syc1119_c	COG0138	bifunctional purine biosynthesis protein purh
syc1121_d	COG0575	Belongs to the CDS family
syc1123_d	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
syc1126_d	COG0438	transferase activity, transferring glycosyl groups
syc1127_c	COG0802	atpase or kinase
syc1128_c	COG0391	Required for morphogenesis under gluconeogenic growth conditions
syc1129_d	COG0644	oxidoreductase
syc1136_c	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
syc1138_d	COG0612	Peptidase, M16
syc1139_d	COG0612	Peptidase, M16
syc1142_c	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
syc1144_c	COG1231	oxidoreductase activity
syc1145_c	COG1570	exodeoxyribonuclease VII activity
syc1146_d	COG0385	Bile acid
syc1154_c	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
syc1155_d	COG0220	tRNA (guanine-N7-)-methyltransferase activity
syc1158_d	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
syc1159_d	COG1472	Belongs to the glycosyl hydrolase 3 family
syc1161_d	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
syc1163_c	COG1127	ABC transporter
syc1165_d	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
syc1168_d	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
syc1168_d	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
syc1174_c	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
syc1175_c	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
syc1176_c	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
syc1177_c	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
syc1178_c	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
syc1179_c	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
syc1181_c	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
syc1182_c	COG0356	it plays a direct role in the translocation of protons across the membrane
syc1184_c	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
syc1185_d	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
syc1189_d	COG0772	Belongs to the SEDS family
syc1190_d	COG4232	protein-disulfide reductase activity
syc1191_d	COG1333	cytochrome c biogenesis protein
syc1192_d	COG0347	Belongs to the P(II) protein family
syc1193_c	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
syc1194_c	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
syc1198_d	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
syc1201_d	COG0792	nuclease activity
syc1202_d	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
syc1203_d	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
syc1204_d	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
syc1206_d	COG0475	glutathione-regulated potassium exporter activity
syc1206_d	COG0589	response to stress
syc1210_d	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
syc1211_c	COG0629	single-stranded DNA binding
syc1212_d	COG1077	Cell shape determining protein MreB Mrl
syc1213_d	COG1792	Involved in formation and maintenance of cell shape
syc1215_c	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
syc1217_c	COG2046	Belongs to the sulfate adenylyltransferase family
syc1220_c	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
syc1221_c	COG3536	Protein conserved in bacteria
syc1222_c	COG0167	dihydroorotate dehydrogenase activity
syc1223_c	COG0653	protein targeting
syc1224_d	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
syc1225_c	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
syc1227_c	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
syc1228_c	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
syc1229_d	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
syc1231_d	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
syc1232_d	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
syc1233_d	COG1058	Belongs to the CinA family
syc1233_d	COG1546	Belongs to the CinA family
syc1236_d	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
syc1237_d	COG0277	FAD linked oxidase domain protein
syc1238_c	COG2361	Protein of unknown function DUF86
syc1240_c	COG0237	dephospho-CoA kinase activity
syc1241_c	COG1587	Uroporphyrinogen-III synthase
syc1242_c	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
syc1243_c	COG0457	Tetratricopeptide repeat
syc1243_c	COG0463	Glycosyl transferase, family 2
syc1246_c	COG0357	Ribosomal RNA small subunit methyltransferase G
syc1247_d	COG0484	heat shock protein binding
syc1249_c	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
syc1250_c	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
syc1251_c	COG0019	diaminopimelate decarboxylase activity
syc1252_d	COG0456	acetyltransferase
syc1253_d	COG0542	response to heat
syc1256_d	COG1836	PFAM Integral membrane protein DUF92
syc1257_c	COG1473	amidohydrolase
syc1259_c	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
syc1264_c	COG1126	abc transporter atp-binding protein
syc1265_c	COG0765	amino acid transport
syc1266_c	COG4597	amino acid ABC transporter
syc1267_c	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
syc1269_d	COG0058	SHG alpha-glucan phosphorylase activity
syc1270_d	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
syc1272_c	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
syc1277_c	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
syc1281_d	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
syc1286_c	COG0193	aminoacyl-tRNA hydrolase activity
syc1287_c	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
syc1291_c	COG0837	glucose binding
syc1294_d	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
syc1295_c	COG0546	phosphoglycolate phosphatase activity
syc1300_c	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
syc1301_c	COG1492	cobalamin metabolic process
syc1303_d	COG0424	maF-like protein
syc1306_c	COG1056	cytidyltransferase-related domain
syc1306_c	COG1051	belongs to the nudix hydrolase family
syc1308_d	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
syc1308_d	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
syc1309_d	COG3278	Belongs to the heme-copper respiratory oxidase family
syc1314_d	COG2211	Major facilitator Superfamily
syc1315_d	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
syc1317_d	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
syc1317_d	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
syc1321_d	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
syc1322_d	COG0518	GMP synthase (glutamine-hydrolyzing) activity
syc1322_d	COG0519	Catalyzes the synthesis of GMP from XMP
syc1323_c	COG1366	Belongs to the anti-sigma-factor antagonist family
syc1324_d	COG1253	flavin adenine dinucleotide binding
syc1325_c	COG0405	Gamma-glutamyltransferase
syc1326_c	COG0306	phosphate transporter
syc1331_c	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
syc1335_c	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
syc1342_c	COG0799	negative regulation of ribosome biogenesis
syc1346_c	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
syc1350_d	COG0033	Phosphoglucomutase
syc1353_d	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
syc1355_d	COG0463	Glycosyl transferase, family 2
syc1356_d	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
syc1362_d	COG0508	dehydrogenase complex catalyzes the overall conversion of
syc1362_d	COG0022	dehydrogenase e1 component
syc1363_d	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
syc1364_d	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
syc1366_c	COG0028	Belongs to the TPP enzyme family
syc1368_c	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
syc1369_d	COG0582	viral genome integration into host DNA
syc1370_d	COG2226	methyltransferase
syc1376_c	COG4372	Transposase
syc1377_c	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
syc1378_d	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
syc1379_d	COG0131	Imidazoleglycerol-phosphate dehydratase
syc1381_d	COG4943	cyclic-guanylate-specific phosphodiesterase activity
syc1383_d	COG0590	tRNA wobble adenosine to inosine editing
syc1386_c	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
syc1392_c	COG0415	Belongs to the DNA photolyase family
syc1393_c	COG0443	Heat shock 70 kDa protein
syc1395_c	COG0783	Belongs to the Dps family
syc1397_d	COG1160	GTP binding
syc1398_d	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
syc1399_d	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
syc1399_d	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
syc1403_c	COG1252	NADH dehydrogenase
syc1406_d	COG0469	pyruvate kinase activity
syc1409_d	COG0745	RESPONSE REGULATOR receiver
syc1410_c	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
syc1411_c	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
syc1414_c	COG1725	Transcriptional regulator
syc1415_d	COG0412	Dienelactone hydrolase
syc1422_c	COG1132	(ABC) transporter
syc1424_d	COG1136	(ABC) transporter
syc1424_d	COG0577	efflux transmembrane transporter activity
syc1425_d	COG0629	single-stranded DNA binding
syc1426_d	COG0432	Pfam Uncharacterised protein family UPF0047
syc1429_c	COG0006	proline dipeptidase activity
syc1431_d	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
syc1435_d	COG1131	(ABC) transporter
syc1438_d	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
syc1440_d	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
syc1442_d	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
syc1449_c	COG1216	Glycosyl transferase, family 2
syc1450_d	COG4969	Belongs to the N-Me-Phe pilin family
syc1451_d	COG4969	Belongs to the N-Me-Phe pilin family
syc1453_c	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
syc1457_d	COG0227	Belongs to the bacterial ribosomal protein bL28 family
syc1458_c	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
syc1459_c	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
syc1460_c	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
syc1461_c	COG1051	belongs to the nudix hydrolase family
syc1465_d	COG2361	Protein of unknown function DUF86
syc1466_c	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
syc1467_c	COG4106	trans-aconitate 2-methyltransferase activity
syc1467_c	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
syc1468_c	COG4106	trans-aconitate 2-methyltransferase activity
syc1470_c	COG0156	8-amino-7-oxononanoate synthase activity
syc1478_c	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
syc1479_d	COG0751	glycine-tRNA ligase activity
syc1480_d	COG0800	Aldolase
syc1482_d	COG3128	pkhd-type hydroxylase
syc1485_d	COG0360	Binds together with S18 to 16S ribosomal RNA
syc1487_d	COG0586	Pfam SNARE associated Golgi protein
syc1488_c	COG0137	argininosuccinate synthase activity
syc1493_c	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
syc1494_c	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
syc1496_c	COG0592	DNA-directed DNA polymerase activity
syc1497_d	COG0546	phosphoglycolate phosphatase activity
syc1498_c	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
syc1500_d	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
syc1504_d	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
syc1506_c	COG1845	cytochrome c oxidase, subunit III
syc1508_c	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
syc1509_d	COG1612	heme a metabolic process
syc1510_d	COG0109	protoheme IX farnesyltransferase activity
syc1514_c	COG0673	inositol 2-dehydrogenase activity
syc1515_c	COG1253	flavin adenine dinucleotide binding
syc1518_d	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
syc1521_c	COG2045	Belongs to the ComB family
syc1522_d	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
syc1525_d	COG1959	2 iron, 2 sulfur cluster binding
syc1526_c	COG1028	Short-chain dehydrogenase reductase Sdr
syc1528_c	COG0483	inositol monophosphate 1-phosphatase activity
syc1529_c	COG0633	Ferredoxin
syc1530_d	COG0443	Heat shock 70 kDa protein
syc1531_d	COG0484	heat shock protein binding
syc1533_d	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
syc1535_c	COG0803	Belongs to the bacterial solute-binding protein 9 family
syc1536_d	COG1121	(ABC) transporter
syc1537_d	COG1108	ABC-type Mn2 Zn2 transport systems permease components
syc1539_c	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
syc1540_d	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
syc1541_d	COG0284	orotidine-5'-phosphate decarboxylase activity
syc1543_c	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
syc1544_c	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
syc1545_d	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
syc1546_d	COG0511	ligase activity, forming carbon-carbon bonds
syc1547_c	COG0419	ATPase involved in DNA repair
syc1548_c	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
syc1551_d	COG0359	binds to the 23S rRNA
syc1552_c	COG1104	cysteine desulfurase activity
syc1554_d	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
syc1555_d	COG3259	Nickel-dependent hydrogenase
syc1557_d	COG0375	protein maturation
syc1558_d	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
syc1559_d	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
syc1560_d	COG0298	carbon dioxide binding
syc1562_c	COG0066	3-isopropylmalate dehydratase activity
syc1565_c	COG0436	Aminotransferase
syc1567_d	COG1573	uracil-dna glycosylase
syc1568_d	COG2010	Cytochrome c
syc1569_c	COG0335	large ribosomal subunit rRNA binding
syc1571_d	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
syc1572_d	COG0740	serine-type endopeptidase activity
syc1573_d	COG0740	serine-type endopeptidase activity
syc1574_d	COG0484	heat shock protein binding
syc1575_c	COG0745	RESPONSE REGULATOR receiver
syc1575_c	COG3706	GGDEF domain
syc1576_d	COG2203	Gaf domain
syc1576_d	COG3706	GGDEF domain
syc1576_d	COG4251	negative regulation of phosphorylation
syc1576_d	COG5001	Diguanylate cyclase
syc1579_c	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
syc1580_c	COG0052	Belongs to the universal ribosomal protein uS2 family
syc1582_c	COG2267	carboxylic ester hydrolase activity
syc1583_c	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
syc1584_c	COG0740	serine-type endopeptidase activity
syc1585_c	COG0544	peptidyl-prolyl cis-trans isomerase activity
syc1586_d	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
syc1589_d	COG0297	glycogen (starch) synthase activity
syc1591_d	COG1074	ATP-dependent DNA helicase activity
syc1592_c	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
syc1593_c	COG0434	BtpA family
syc1594_d	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
syc1596_c	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
syc1598_c	COG1252	NADH dehydrogenase
syc1600_d	COG0175	sulfate reduction
syc1605_c	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
syc1607_d	COG2268	Band 7 protein
syc1609_d	COG0105	UTP biosynthetic process
syc1611_d	COG0559	Belongs to the binding-protein-dependent transport system permease family
syc1613_d	COG0411	ABC transporter
syc1615_c	COG0187	DNA topoisomerase II activity
syc1615_c	COG1372	Participates in initiation and elongation during chromosome replication
syc1616_d	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
syc1624_d	COG3751	2OG-Fe(II) oxygenase superfamily
syc1627_d	COG1090	epimerase
syc1629_c	COG0165	Argininosuccinate lyase
syc1631_c	COG2208	phosphoserine phosphatase activity
syc1632_c	COG0552	protein localization to endoplasmic reticulum
syc1633_c	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
syc1636_c	COG0443	Heat shock 70 kDa protein
syc1638_c	COG0745	RESPONSE REGULATOR receiver
syc1640_d	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
syc1641_d	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
syc1642_d	COG1070	Carbohydrate kinase
syc1643_d	COG2957	Belongs to the agmatine deiminase family
syc1647_c	COG0752	glycyl-tRNA synthetase alpha subunit
syc1650_d	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
syc1651_d	COG0601	transmembrane transport
syc1657_c	COG0450	alkyl hydroperoxide reductase
syc1658_c	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
syc1660_d	COG0024	Methionine aminopeptidase
syc1661_d	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
syc1662_d	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
syc1663_d	COG0573	inorganic phosphate transmembrane transporter activity
syc1664_d	COG0581	inorganic phosphate transmembrane transporter activity
syc1665_d	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
syc1666_d	COG1185	polyribonucleotide nucleotidyltransferase activity
syc1669_d	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
syc1670_d	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
syc1672_c	COG0440	acetolactate synthase activity
syc1673_c	COG1073	alpha beta
syc1673_c	COG2226	methyltransferase
syc1674_c	COG4636	protein conserved in cyanobacteria
syc1677_d	COG0811	peptide transport
syc1678_d	COG0848	biopolymer transport protein
syc1683_d	COG0445	tRNA wobble uridine modification
syc1685_d	COG0672	)-iron permease
syc1686_c	COG1045	serine acetyltransferase
syc1688_d	COG0583	DNA-binding transcription factor activity
syc1691_d	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
syc1692_d	COG2226	methyltransferase
syc1693_d	COG0330	HflC and HflK could
syc1696_d	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
syc1699_c	COG2022	thiamine diphosphate biosynthetic process
syc1699_c	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
syc1700_d	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
syc1701_c	COG1040	competence protein
syc1703_c	COG2957	Belongs to the agmatine deiminase family
syc1704_d	COG0071	Belongs to the small heat shock protein (HSP20) family
syc1707_d	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
syc1712_c	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
syc1717_d	COG2140	Oxalate decarboxylase
syc1719_c	COG0409	Hydrogenase expression formation protein
syc1720_c	COG0167	dihydroorotate dehydrogenase activity
syc1721_c	COG0674	pyruvate-flavodoxin oxidoreductase activity
syc1721_c	COG1013	pyruvate-flavodoxin oxidoreductase activity
syc1721_c	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
syc1721_c	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
syc1722_c	COG4956	integral membrane protein (PIN domain superfamily)
syc1723_d	COG0635	Involved in the biosynthesis of porphyrin-containing compound
syc1724_c	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
syc1726_c	COG0351	phosphomethylpyrimidine kinase
syc1727_c	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
syc1730_c	COG1181	Belongs to the D-alanine--D-alanine ligase family
syc1731_c	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
syc1732_d	COG4948	Mandelate Racemase Muconate Lactonizing
syc1738_c	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
syc1741_c	COG0142	geranyltranstransferase activity
syc1744_c	COG0475	glutathione-regulated potassium exporter activity
syc1745_c	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
syc1747_d	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
syc1750_c	COG0321	lipoyl(octanoyl) transferase activity
syc1751_d	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
syc1752_c	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
syc1753_d	COG0009	L-threonylcarbamoyladenylate synthase
syc1755_c	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
syc1762_c	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
syc1763_c	COG1160	GTP binding
syc1767_d	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
syc1768_d	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
syc1769_d	COG3409	Peptidoglycan-binding domain 1 protein
syc1769_d	COG3429	Glucose-6-phosphate dehydrogenase subunit
syc1770_c	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
syc1771_c	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
syc1772_d	COG0793	Belongs to the peptidase S41A family
syc1773_d	COG1078	dGTPase activity
syc1778_c	COG0189	ligase activity
syc1779_c	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
syc1781_c	COG0457	Tetratricopeptide repeat
syc1783_c	COG3093	addiction module antidote protein HigA
syc1784_c	COG3224	Antibiotic biosynthesis monooxygenase
syc1785_d	COG2217	Heavy metal translocating P-type atpase
syc1786_c	COG0355	proton-transporting ATP synthase activity, rotational mechanism
syc1787_c	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
syc1788_d	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
syc1789_d	COG0459	protein refolding
syc1790_c	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
syc1792_d	COG0076	glutamate decarboxylase activity
syc1793_d	COG0450	alkyl hydroperoxide reductase
syc1794_c	COG0404	The glycine cleavage system catalyzes the degradation of glycine
syc1796_c	COG0745	RESPONSE REGULATOR receiver
syc1797_c	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
syc1798_c	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
syc1801_c	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
syc1802_c	COG0632	four-way junction helicase activity
syc1803_d	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
syc1810_d	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
syc1811_d	COG2877	3-deoxy-8-phosphooctulonate synthase activity
syc1812_d	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
syc1815_d	COG0371	Dehydrogenase
syc1816_d	COG2267	carboxylic ester hydrolase activity
syc1817_c	COG1811	Na channel or pump
syc1818_d	COG5002	protein histidine kinase activity
syc1825_c	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
syc1825_c	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
syc1827_d	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
syc1831_d	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
syc1833_c	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
syc1835_d	COG0124	histidyl-tRNA synthetase
syc1839_c	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
syc1840_c	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
syc1845_d	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
syc1846_d	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
syc1848_d	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
syc1849_d	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
syc1850_d	COG0776	regulation of translation
syc1851_c	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
syc1854_d	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
syc1855_d	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
syc1858_c	COG0456	acetyltransferase
syc1860_d	COG0477	Major facilitator Superfamily
syc1862_d	COG4172	Belongs to the ABC transporter superfamily
syc1863_c	COG0336	Belongs to the RNA methyltransferase TrmD family
syc1865_d	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
syc1866_d	COG0088	Forms part of the polypeptide exit tunnel
syc1867_d	COG0089	rRNA binding
syc1868_d	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
syc1869_d	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
syc1870_d	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
syc1871_d	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
syc1872_d	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
syc1873_d	COG0255	Belongs to the universal ribosomal protein uL29 family
syc1874_d	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
syc1875_d	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
syc1876_d	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
syc1877_d	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
syc1878_d	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
syc1879_d	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
syc1880_d	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
syc1881_d	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
syc1882_d	COG0200	Binds to the 23S rRNA
syc1883_d	COG0201	protein transport
syc1884_d	COG0563	adenylate kinase activity
syc1885_d	COG0257	Belongs to the bacterial ribosomal protein bL36 family
syc1886_d	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
syc1887_d	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
syc1888_d	COG0202	RNA polymerase activity
syc1889_d	COG0203	ribosomal protein L17
syc1890_d	COG0101	tRNA pseudouridine synthase activity
syc1891_d	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
syc1892_d	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
syc1893_d	COG0254	rRNA binding
syc1894_d	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
syc1896_d	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
syc1898_d	COG0587	DNA-directed DNA polymerase activity
syc1900_c	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
syc1904_d	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
syc1905_c	COG5001	Diguanylate cyclase
syc1905_c	COG3300	MHYT domain
syc1907_c	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
syc1912_c	COG0121	glutamine amidotransferase
syc1913_d	COG0328	RNA-DNA hybrid ribonuclease activity
syc1914_d	COG1994	Peptidase M50
syc1914_d	COG0517	IMP dehydrogenase activity
syc1915_d	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
syc1916_d	COG1803	Methylglyoxal synthase
syc1916_d	COG1597	lipid kinase activity
syc1917_d	COG1950	PFAM Membrane protein of
syc1920_d	COG1840	ABC-type Fe3 transport system, periplasmic component
syc1921_c	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
syc1924_d	COG0783	Belongs to the Dps family
syc1925_c	COG0735	belongs to the Fur family
syc1934_c	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
syc1935_c	COG2267	carboxylic ester hydrolase activity
syc1938_d	COG0174	glutamine synthetase
syc1946_d	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
syc1948_c	COG0133	tryptophan synthase activity
syc1949_d	COG0023	Translation Initiation Factor
syc1953_c	COG0625	glutathione transferase activity
syc1955_c	COG1429	ligase activity, forming nitrogen-metal bonds
syc1956_d	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
syc1958_d	COG0860	N-Acetylmuramoyl-L-alanine amidase
syc1960_c	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
syc1964_d	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
syc1968_d	COG0123	including yeast histone deacetylase and acetoin utilization protein
syc1969_d	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
syc1970_d	COG0505	Belongs to the CarA family
syc1972_d	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
syc1973_d	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
syc1975_d	COG0154	amidase activity
syc1978_c	COG2205	protein histidine kinase activity
syc1979_c	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
syc1981_c	COG1940	carbohydrate kinase activity
syc1982_d	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
syc1983_c	COG1132	(ABC) transporter
syc1986_d	COG1116	anion transmembrane transporter activity
syc1986_d	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
syc1987_d	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
syc1988_d	COG1116	anion transmembrane transporter activity
syc1989_d	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
syc1997_c	COG3706	GGDEF domain
syc1997_c	COG4251	negative regulation of phosphorylation
syc1997_c	COG5001	Diguanylate cyclase
syc1997_c	COG2203	Gaf domain
syc1999_c	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
syc2001_c	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
syc2002_c	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
syc2003_c	COG0460	homoserine dehydrogenase
syc2004_d	COG4243	Vitamin k epoxide reductase
syc2006_c	COG0107	imidazoleglycerol-phosphate synthase activity
syc2009_d	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
syc2010_c	COG2095	MarC family integral membrane protein
syc2011_d	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
syc2013_c	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
syc2014_d	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
syc2019_c	COG0484	heat shock protein binding
syc2020_c	COG0443	Heat shock 70 kDa protein
syc2021_c	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
syc2022_d	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
syc2026_c	COG2081	HI0933 family
syc2027_d	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
syc2029_c	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
syc2030_d	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
syc2031_d	COG0644	oxidoreductase
syc2033_d	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
syc2034_d	COG1799	cell septum assembly
syc2035_d	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
syc2036_c	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
syc2038_c	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
syc2044_d	COG2885	chlorophyll binding
syc2045_d	COG2885	chlorophyll binding
syc2046_c	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
syc2046_c	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
syc2047_c	COG0509	glycine decarboxylation via glycine cleavage system
syc2048_d	COG1196	nuclear chromosome segregation
syc2050_d	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
syc2053_c	COG0728	peptidoglycan biosynthetic process
syc2054_d	COG1489	DNA binding
syc2061_c	COG1819	glycosyl
syc2065_d	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
syc2066_c	COG0166	Belongs to the GPI family
syc2067_c	COG0438	transferase activity, transferring glycosyl groups
syc2068_c	COG1215	transferase activity, transferring glycosyl groups
syc2072_d	COG0779	Required for maturation of 30S ribosomal subunits
syc2073_d	COG0195	Participates in both transcription termination and antitermination
syc2075_d	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
syc2080_d	COG0515	serine threonine protein kinase
syc2083_c	COG2385	sporulation resulting in formation of a cellular spore
syc2084_d	COG1234	tRNA 3'-trailer cleavage
syc2085_d	COG2010	Cytochrome c
syc2086_c	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
syc2087_c	COG0426	domain, Protein
syc2087_c	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
syc2088_d	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
syc2091_c	COG1595	DNA-templated transcription, initiation
syc2095_d	COG0850	regulation of cytokinetic process
syc2097_d	COG0724	RNA recognition motif
syc2099_d	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
syc2101_d	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
syc2101_d	COG0140	phosphoribosyl-ATP diphosphatase activity
syc2102_c	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
syc2103_c	COG0235	Class ii aldolase
syc2104_d	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
syc2105_d	COG1970	mechanosensitive ion channel activity
syc2106_d	COG2119	membrane
syc2107_d	COG1230	cation diffusion facilitator family transporter
syc2110_d	COG0612	Peptidase, M16
syc2112_c	COG1562	ergosterol biosynthetic process
syc2113_c	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
syc2113_c	COG0493	'glutamate synthase
syc2118_d	COG3118	belongs to the thioredoxin family
syc2119_d	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
syc2120_d	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
syc2123_d	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
syc2125_d	COG1473	amidohydrolase
syc2128_c	COG1968	undecaprenyl-diphosphatase activity
syc2131_d	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
syc2132_d	COG1619	proteins homologs of microcin C7 resistance protein MccF
syc2134_c	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
syc2136_c	COG0442	prolyl-tRNA aminoacylation
syc2139_c	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
syc2140_d	COG0504	CTP synthase activity
syc2149_d	COG0322	excinuclease ABC activity
syc2150_c	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
syc2152_c	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
syc2153_c	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
syc2153_c	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
syc2155_c	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
syc2156_d	COG0798	PFAM Bile acid sodium symporter
syc2157_d	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
syc2159_d	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
syc2161_c	COG1304	FMN binding
syc2163_c	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
syc2165_c	COG1104	cysteine desulfurase activity
syc2167_c	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
syc2171_d	COG1595	DNA-templated transcription, initiation
syc2174_d	COG0495	leucyl-tRNA aminoacylation
syc2177_c	COG0697	spore germination
syc2178_d	COG0616	signal peptide processing
syc2183_d	COG0704	Plays a role in the regulation of phosphate uptake
syc2184_d	COG0557	exoribonuclease II activity
syc2185_d	COG0163	prenyltransferase activity
syc2188_d	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
syc2189_d	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
syc2195_c	COG0717	Belongs to the dCTP deaminase family
syc2197_d	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
syc2199_d	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
syc2202_d	COG0411	ABC transporter
syc2206_d	COG1543	Belongs to the glycosyl hydrolase 57 family
syc2209_c	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
syc2209_c	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
syc2210_d	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
syc2211_d	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
syc2211_d	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
syc2212_d	COG0515	serine threonine protein kinase
syc2213_d	COG1555	photosystem II stabilization
syc2214_d	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
syc2215_d	COG0714	Associated with various cellular activities
syc2219_d	COG0312	modulator of DNA gyrase
syc2220_d	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
syc2222_c	COG5002	protein histidine kinase activity
syc2224_d	COG1566	PFAM secretion protein HlyD family protein
syc2229_c	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
syc2230_c	COG0009	L-threonylcarbamoyladenylate synthase
syc2231_c	COG2890	protein-(glutamine-N5) methyltransferase activity
syc2234_d	COG0745	RESPONSE REGULATOR receiver
syc2236_c	COG5398	heme oxygenase
syc2237_d	COG2084	Dehydrogenase
syc2239_c	COG1797	cobyrinic acid a,c-diamide synthase activity
syc2245_c	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
syc2246_d	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
syc2247_d	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
syc2248_d	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
syc2250_d	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
syc2253_d	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
syc2256_d	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
syc2261_c	COG1192	Involved in chromosome partitioning
syc2262_d	COG0525	valine-tRNA ligase activity
syc2263_d	COG0516	GMP reductase activity
syc2264_d	COG3118	belongs to the thioredoxin family
syc2265_c	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
syc2269_c	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
syc2270_d	COG0517	IMP dehydrogenase activity
syc2270_d	COG0516	GMP reductase activity
syc2274_d	COG0670	Belongs to the BI1 family
syc2275_c	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
syc2277_d	COG3706	GGDEF domain
syc2277_d	COG0745	RESPONSE REGULATOR receiver
syc2279_d	COG0745	RESPONSE REGULATOR receiver
syc2280_d	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
syc2282_c	COG5002	protein histidine kinase activity
syc2282_c	COG5001	Diguanylate cyclase
syc2282_c	COG3447	MASE1 domain protein
syc2283_c	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
syc2283_c	COG0426	domain, Protein
syc2284_c	COG0426	domain, Protein
syc2284_c	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
syc2285_d	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
syc2287_c	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
syc2291_d	COG2197	response regulator
syc2292_c	COG0596	Alpha beta hydrolase
syc2298_d	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
syc2299_c	COG0436	Aminotransferase
syc2300_c	COG3118	belongs to the thioredoxin family
syc2301_c	COG0113	porphobilinogen synthase activity
syc2302_d	COG2133	pyrroloquinoline quinone binding
syc2303_c	COG0338	D12 class N6 adenine-specific DNA methyltransferase
syc2304_c	COG0484	heat shock protein binding
syc2310_c	COG1615	UPF0182 protein
syc2311_d	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
syc2312_d	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
syc2313_c	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
syc2314_c	COG0497	DNA recombination
syc2315_d	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
syc2317_c	COG1702	phosphate starvation-inducible protein PhoH
syc2318_c	COG0828	Belongs to the bacterial ribosomal protein bS21 family
syc2320_c	COG0228	four-way junction DNA binding
syc2321_c	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
syc2325_d	COG1271	oxidase subunit
syc2329_c	COG0483	inositol monophosphate 1-phosphatase activity
syc2332_c	COG0686	Belongs to the AlaDH PNT family
syc2333_d	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
syc2334_d	COG0820	rRNA (adenine-C2-)-methyltransferase activity
syc2338_d	COG0456	acetyltransferase
syc2345_d	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
syc2347_c	COG0824	Thioesterase
syc2348_c	COG0649	NAD binding
syc2349_c	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
syc2350_d	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
syc2351_d	COG0812	UDP-N-acetylmuramate dehydrogenase activity
syc2353_c	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
syc2354_c	COG0719	Fe-S assembly protein
syc2355_c	COG0396	ATPase activity
syc2356_c	COG0719	Fe-S assembly protein
syc2357_c	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
syc2360_d	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
syc2362_c	COG2205	protein histidine kinase activity
syc2365_d	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
syc2366_c	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
syc2369_d	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
syc2372_d	COG0538	isocitrate dehydrogenase activity
syc2373_d	COG0277	FAD linked oxidase domain protein
syc2374_d	COG0247	lactate metabolic process
syc2376_d	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
syc2377_c	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
syc2382_d	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
syc2383_c	COG0339	signal peptide processing
syc2388_d	COG0383	alpha-mannosidase activity
syc2390_d	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
syc2391_d	COG0534	Mate efflux family protein
syc2392_c	COG1733	regulation of RNA biosynthetic process
syc2394_d	COG1741	Belongs to the pirin family
syc2396_c	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
syc2398_d	COG1715	Restriction endonuclease
syc2401_c	COG2897	thiosulfate sulfurtransferase activity
syc2402_c	COG4208	sulfate ABC transporter
syc2403_c	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
syc2404_c	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
syc2405_c	COG4208	sulfate ABC transporter
syc2406_c	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
syc2407_c	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
syc2408_c	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
syc2409_c	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
syc2410_d	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
syc2413_d	COG2022	thiamine diphosphate biosynthetic process
syc2413_d	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
syc2419_c	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
syc2420_c	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
syc2422_c	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
syc2424_c	COG0673	inositol 2-dehydrogenase activity
syc2426_d	COG0215	cysteine-tRNA ligase activity
syc2428_c	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
syc2429_c	COG0778	Nitroreductase
syc2431_d	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
syc2433_d	COG0371	Dehydrogenase
syc2436_d	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
syc2437_c	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
syc2437_c	COG1773	rubredoxin
syc2441_c	COG0571	ribonuclease III activity
syc2443_c	COG4251	negative regulation of phosphorylation
syc2443_c	COG2203	Gaf domain
syc2443_c	COG5001	Diguanylate cyclase
syc2443_c	COG3706	GGDEF domain
syc2445_c	COG3688	RNA-binding protein containing a PIN domain
syc2446_c	COG1122	ATPase activity
syc2450_d	COG3659	wide pore channel activity
syc2451_d	COG3659	wide pore channel activity
syc2452_d	COG1959	2 iron, 2 sulfur cluster binding
syc2453_d	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
syc2460_c	COG1006	Multisubunit Na H antiporter MnhC subunit
syc2462_d	COG0347	Belongs to the P(II) protein family
syc2464_c	COG2010	Cytochrome c
syc2466_c	COG0742	ribosomal rna small subunit methyltransferase
syc2467_c	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
syc2470_c	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
syc2472_c	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
syc2473_d	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
syc2474_d	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
syc2475_d	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
syc2476_d	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
syc2476_d	COG1116	anion transmembrane transporter activity
syc2477_d	COG1116	anion transmembrane transporter activity
syc2479_d	COG3956	TIGRFAM MazG family protein
syc2482_c	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
syc2484_c	COG0633	Ferredoxin
syc2485_c	COG2264	protein methyltransferase activity
syc2486_c	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
syc2490_c	COG0473	3-isopropylmalate dehydrogenase activity
syc2492_c	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
syc2494_d	COG0482	sulfurtransferase activity
syc2495_c	COG1191	sigma factor activity
syc2497_c	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
syc2498_d	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
syc2499_d	COG1187	pseudouridine synthase activity
syc2502_c	COG5002	protein histidine kinase activity
syc2504_c	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
syc2505_d	COG0268	Binds directly to 16S ribosomal RNA
syc2506_d	COG0084	hydrolase, TatD family'
syc2507_d	COG0085	RNA polymerase activity
syc2508_d	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
syc2509_d	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
syc2513_d	COG3604	Transcriptional regulator
syc2517_d	COG0725	ABC transporter, periplasmic molybdate-binding protein
syc2518_d	COG4149	molybdate abc transporter
syc2525_c	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis