locus-tag	class	description
PCC6301pg_0001	COG0592	DNA-directed DNA polymerase activity
PCC6301pg_0003	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PCC6301pg_0004	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PCC6301pg_0009	COG0137	argininosuccinate synthase activity
PCC6301pg_0010	COG0586	Pfam SNARE associated Golgi protein
PCC6301pg_0012	COG0360	Binds together with S18 to 16S ribosomal RNA
PCC6301pg_0015	COG3128	pkhd-type hydroxylase
PCC6301pg_0018	COG0800	Aldolase
PCC6301pg_0019	COG0751	glycine-tRNA ligase activity
PCC6301pg_0020	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PCC6301pg_0028	COG0156	8-amino-7-oxononanoate synthase activity
PCC6301pg_0030	COG4106	trans-aconitate 2-methyltransferase activity
PCC6301pg_0031	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PCC6301pg_0031	COG4106	trans-aconitate 2-methyltransferase activity
PCC6301pg_0032	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PCC6301pg_0033	COG2361	Protein of unknown function DUF86
PCC6301pg_0035	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PCC6301pg_0040	COG1051	belongs to the nudix hydrolase family
PCC6301pg_0041	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PCC6301pg_0042	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PCC6301pg_0043	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PCC6301pg_0044	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PCC6301pg_0048	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PCC6301pg_0050	COG4969	Belongs to the N-Me-Phe pilin family
PCC6301pg_0051	COG4969	Belongs to the N-Me-Phe pilin family
PCC6301pg_0052	COG1216	Glycosyl transferase, family 2
PCC6301pg_0060	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
PCC6301pg_0064	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PCC6301pg_0066	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PCC6301pg_0069	COG1131	(ABC) transporter
PCC6301pg_0074	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PCC6301pg_0076	COG0006	proline dipeptidase activity
PCC6301pg_0079	COG0432	Pfam Uncharacterised protein family UPF0047
PCC6301pg_0080	COG0629	single-stranded DNA binding
PCC6301pg_0081	COG0577	efflux transmembrane transporter activity
PCC6301pg_0081	COG1136	(ABC) transporter
PCC6301pg_0082	COG2501	S4 domain
PCC6301pg_0083	COG1132	(ABC) transporter
PCC6301pg_0092	COG0412	Dienelactone hydrolase
PCC6301pg_0093	COG1725	Transcriptional regulator
PCC6301pg_0096	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PCC6301pg_0097	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PCC6301pg_0098	COG0745	RESPONSE REGULATOR receiver
PCC6301pg_0101	COG0469	pyruvate kinase activity
PCC6301pg_0104	COG1252	NADH dehydrogenase
PCC6301pg_0108	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PCC6301pg_0108	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PCC6301pg_0109	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PCC6301pg_0110	COG1160	GTP binding
PCC6301pg_0112	COG0783	Belongs to the Dps family
PCC6301pg_0114	COG0443	Heat shock 70 kDa protein
PCC6301pg_0115	COG0415	Belongs to the DNA photolyase family
PCC6301pg_0121	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PCC6301pg_0124	COG0590	tRNA wobble adenosine to inosine editing
PCC6301pg_0127	COG4943	cyclic-guanylate-specific phosphodiesterase activity
PCC6301pg_0129	COG0500	methyltransferase
PCC6301pg_0130	COG0131	Imidazoleglycerol-phosphate dehydratase
PCC6301pg_0131	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PCC6301pg_0132	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PCC6301pg_0133	COG4372	Transposase
PCC6301pg_0140	COG2226	methyltransferase
PCC6301pg_0141	COG0582	viral genome integration into host DNA
PCC6301pg_0142	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PCC6301pg_0144	COG0028	Belongs to the TPP enzyme family
PCC6301pg_0146	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PCC6301pg_0147	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PCC6301pg_0148	COG0022	dehydrogenase e1 component
PCC6301pg_0148	COG0508	dehydrogenase complex catalyzes the overall conversion of
PCC6301pg_0154	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PCC6301pg_0155	COG0463	Glycosyl transferase, family 2
PCC6301pg_0157	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PCC6301pg_0161	COG0033	Phosphoglucomutase
PCC6301pg_0165	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PCC6301pg_0169	COG0799	negative regulation of ribosome biogenesis
PCC6301pg_0180	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PCC6301pg_0185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PCC6301pg_0190	COG0306	phosphate transporter
PCC6301pg_0191	COG0405	Gamma-glutamyltransferase
PCC6301pg_0193	COG1253	flavin adenine dinucleotide binding
PCC6301pg_0194	COG1366	Belongs to the anti-sigma-factor antagonist family
PCC6301pg_0195	COG0519	Catalyzes the synthesis of GMP from XMP
PCC6301pg_0195	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PCC6301pg_0196	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
PCC6301pg_0200	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PCC6301pg_0200	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PCC6301pg_0202	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
PCC6301pg_0203	COG2211	Major facilitator Superfamily
PCC6301pg_0208	COG3278	Belongs to the heme-copper respiratory oxidase family
PCC6301pg_0209	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PCC6301pg_0209	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PCC6301pg_0211	COG1056	cytidyltransferase-related domain
PCC6301pg_0211	COG1051	belongs to the nudix hydrolase family
PCC6301pg_0215	COG0424	maF-like protein
PCC6301pg_0217	COG1492	cobalamin metabolic process
PCC6301pg_0218	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PCC6301pg_0223	COG0546	phosphoglycolate phosphatase activity
PCC6301pg_0225	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
PCC6301pg_0228	COG0837	glucose binding
PCC6301pg_0233	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PCC6301pg_0234	COG0193	aminoacyl-tRNA hydrolase activity
PCC6301pg_0239	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PCC6301pg_0243	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PCC6301pg_0246	COG2010	Cytochrome c
PCC6301pg_0248	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PCC6301pg_0251	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PCC6301pg_0252	COG0058	SHG alpha-glucan phosphorylase activity
PCC6301pg_0253	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PCC6301pg_0254	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCC6301pg_0255	COG4597	amino acid ABC transporter
PCC6301pg_0256	COG0765	amino acid transport
PCC6301pg_0257	COG1126	abc transporter atp-binding protein
PCC6301pg_0262	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PCC6301pg_0264	COG1473	amidohydrolase
PCC6301pg_0265	COG1836	PFAM Integral membrane protein DUF92
PCC6301pg_0268	COG0542	response to heat
PCC6301pg_0269	COG0456	acetyltransferase
PCC6301pg_0270	COG0019	diaminopimelate decarboxylase activity
PCC6301pg_0271	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PCC6301pg_0272	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PCC6301pg_0274	COG0484	heat shock protein binding
PCC6301pg_0275	COG0357	Ribosomal RNA small subunit methyltransferase G
PCC6301pg_0278	COG0457	Tetratricopeptide repeat
PCC6301pg_0278	COG0463	Glycosyl transferase, family 2
PCC6301pg_0279	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PCC6301pg_0280	COG1587	Uroporphyrinogen-III synthase
PCC6301pg_0281	COG0237	dephospho-CoA kinase activity
PCC6301pg_0283	COG2361	Protein of unknown function DUF86
PCC6301pg_0284	COG0277	FAD linked oxidase domain protein
PCC6301pg_0285	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PCC6301pg_0288	COG1058	Belongs to the CinA family
PCC6301pg_0288	COG1546	Belongs to the CinA family
PCC6301pg_0289	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PCC6301pg_0290	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PCC6301pg_0291	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PCC6301pg_0292	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
PCC6301pg_0293	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
PCC6301pg_0295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PCC6301pg_0296	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PCC6301pg_0297	COG0653	protein targeting
PCC6301pg_0298	COG0167	dihydroorotate dehydrogenase activity
PCC6301pg_0300	COG3536	Protein conserved in bacteria
PCC6301pg_0301	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PCC6301pg_0304	COG2046	Belongs to the sulfate adenylyltransferase family
PCC6301pg_0306	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PCC6301pg_0308	COG1792	Involved in formation and maintenance of cell shape
PCC6301pg_0309	COG1077	Cell shape determining protein MreB Mrl
PCC6301pg_0310	COG0629	single-stranded DNA binding
PCC6301pg_0311	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PCC6301pg_0316	COG0589	response to stress
PCC6301pg_0316	COG0475	glutathione-regulated potassium exporter activity
PCC6301pg_0318	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PCC6301pg_0319	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PCC6301pg_0320	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PCC6301pg_0321	COG0792	nuclease activity
PCC6301pg_0324	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PCC6301pg_0328	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
PCC6301pg_0329	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PCC6301pg_0330	COG0347	Belongs to the P(II) protein family
PCC6301pg_0331	COG1333	cytochrome c biogenesis protein
PCC6301pg_0332	COG4232	protein-disulfide reductase activity
PCC6301pg_0333	COG0772	Belongs to the SEDS family
PCC6301pg_0337	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PCC6301pg_0338	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PCC6301pg_0340	COG0356	it plays a direct role in the translocation of protons across the membrane
PCC6301pg_0341	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PCC6301pg_0342	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PCC6301pg_0343	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PCC6301pg_0344	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PCC6301pg_0345	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PCC6301pg_0346	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PCC6301pg_0347	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PCC6301pg_0349	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PCC6301pg_0355	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
PCC6301pg_0355	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
PCC6301pg_0356	COG1496	oxidoreductase activity
PCC6301pg_0358	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PCC6301pg_0360	COG1127	ABC transporter
PCC6301pg_0362	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PCC6301pg_0365	COG1472	Belongs to the glycosyl hydrolase 3 family
PCC6301pg_0366	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PCC6301pg_0370	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PCC6301pg_0371	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PCC6301pg_0379	COG0385	Bile acid
PCC6301pg_0380	COG1570	exodeoxyribonuclease VII activity
PCC6301pg_0381	COG1231	oxidoreductase activity
PCC6301pg_0383	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
PCC6301pg_0385	COG2850	peptidyl-arginine hydroxylation
PCC6301pg_0387	COG0612	Peptidase, M16
PCC6301pg_0388	COG0612	Peptidase, M16
PCC6301pg_0390	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PCC6301pg_0398	COG0644	oxidoreductase
PCC6301pg_0399	COG0391	Required for morphogenesis under gluconeogenic growth conditions
PCC6301pg_0400	COG0802	atpase or kinase
PCC6301pg_0401	COG0438	transferase activity, transferring glycosyl groups
PCC6301pg_0405	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
PCC6301pg_0407	COG0575	Belongs to the CDS family
PCC6301pg_0409	COG0138	bifunctional purine biosynthesis protein purh
PCC6301pg_0413	COG0512	Glutamine amidotransferase of anthranilate synthase
PCC6301pg_0414	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PCC6301pg_0415	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PCC6301pg_0421	COG0135	phosphoribosylanthranilate isomerase activity
PCC6301pg_0424	COG0159	tryptophan synthase activity
PCC6301pg_0433	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PCC6301pg_0435	COG3788	relative of glutathione S-transferase, MAPEG superfamily
PCC6301pg_0441	COG1131	(ABC) transporter
PCC6301pg_0442	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PCC6301pg_0444	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PCC6301pg_0446	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
PCC6301pg_0449	COG0701	Predicted permease
PCC6301pg_0451	COG1403	HNH endonuclease
PCC6301pg_0454	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PCC6301pg_0455	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PCC6301pg_0456	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PCC6301pg_0457	COG0004	ammonium transporteR
PCC6301pg_0458	COG1361	Conserved repeat domain
PCC6301pg_0460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PCC6301pg_0461	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PCC6301pg_0462	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PCC6301pg_0463	COG0750	zinc metalloprotease
PCC6301pg_0464	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PCC6301pg_0465	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PCC6301pg_0468	COG2205	protein histidine kinase activity
PCC6301pg_0469	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PCC6301pg_0470	COG0343	queuine tRNA-ribosyltransferase activity
PCC6301pg_0474	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
PCC6301pg_0475	COG0456	acetyltransferase
PCC6301pg_0478	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PCC6301pg_0479	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PCC6301pg_0481	COG1215	transferase activity, transferring glycosyl groups
PCC6301pg_0484	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PCC6301pg_0487	COG0395	ABC-type sugar transport system, permease component
PCC6301pg_0488	COG1722	exodeoxyribonuclease VII activity
PCC6301pg_0489	COG1902	pentaerythritol trinitrate reductase activity
PCC6301pg_0492	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PCC6301pg_0493	COG0762	integral membrane protein
PCC6301pg_0494	COG0681	Belongs to the peptidase S26 family
PCC6301pg_0495	COG0481	GTPase activity
PCC6301pg_0497	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PCC6301pg_0498	COG0768	penicillin binding
PCC6301pg_0501	COG0406	alpha-ribazole phosphatase activity
PCC6301pg_0502	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PCC6301pg_0504	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PCC6301pg_0505	COG1012	belongs to the aldehyde dehydrogenase family
PCC6301pg_0506	COG3300	MHYT domain
PCC6301pg_0506	COG5001	Diguanylate cyclase
PCC6301pg_0508	COG0196	riboflavin kinase activity
PCC6301pg_0514	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PCC6301pg_0517	COG0702	epimerase
PCC6301pg_0520	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PCC6301pg_0521	COG1494	fructose-1,6-bisphosphatase
PCC6301pg_0522	COG0528	UMP kinase activity
PCC6301pg_0523	COG0233	cytoplasmic translational termination
PCC6301pg_0524	COG0644	oxidoreductase
PCC6301pg_0527	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PCC6301pg_0532	COG0793	Belongs to the peptidase S41A family
PCC6301pg_0533	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PCC6301pg_0533	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
PCC6301pg_0534	COG0628	permease
PCC6301pg_0536	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
PCC6301pg_0542	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PCC6301pg_0543	COG1175	transmembrane transport
PCC6301pg_0546	COG0363	glucosamine-6-phosphate deaminase activity
PCC6301pg_0547	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PCC6301pg_0551	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PCC6301pg_0552	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PCC6301pg_0553	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PCC6301pg_0554	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PCC6301pg_0555	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PCC6301pg_0560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PCC6301pg_0564	COG0475	glutathione-regulated potassium exporter activity
PCC6301pg_0567	COG0861	Integral membrane protein TerC family
PCC6301pg_0571	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PCC6301pg_0572	COG0012	GTP binding
PCC6301pg_0574	COG0745	RESPONSE REGULATOR receiver
PCC6301pg_0577	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PCC6301pg_0578	COG1122	ATPase activity
PCC6301pg_0581	COG0556	nucleotide-excision repair
PCC6301pg_0582	COG1136	(ABC) transporter
PCC6301pg_0585	COG0277	FAD linked oxidase domain protein
PCC6301pg_0586	COG0402	S-adenosylhomocysteine deaminase activity
PCC6301pg_0587	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PCC6301pg_0588	COG0587	DNA-directed DNA polymerase activity
PCC6301pg_0589	COG2211	Major facilitator Superfamily
PCC6301pg_0590	COG0346	lactoylglutathione lyase activity
PCC6301pg_0595	COG2022	thiamine diphosphate biosynthetic process
PCC6301pg_0601	COG0429	hydrolase of the alpha beta-hydrolase fold
PCC6301pg_0602	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
PCC6301pg_0603	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PCC6301pg_0604	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PCC6301pg_0605	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PCC6301pg_0611	COG0525	valine-tRNA ligase activity
PCC6301pg_0612	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PCC6301pg_0616	COG2119	membrane
PCC6301pg_0617	COG0205	6-phosphofructokinase activity
PCC6301pg_0621	COG2226	methyltransferase
PCC6301pg_0626	COG0515	serine threonine protein kinase
PCC6301pg_0629	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PCC6301pg_0630	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PCC6301pg_0631	COG3781	membrane
PCC6301pg_0632	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PCC6301pg_0634	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PCC6301pg_0635	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PCC6301pg_0636	COG0668	transmembrane transport
PCC6301pg_0637	COG1193	negative regulation of DNA recombination
PCC6301pg_0638	COG0372	Belongs to the citrate synthase family
PCC6301pg_0639	COG2062	phosphohistidine phosphatase, SixA
PCC6301pg_0641	COG1054	Belongs to the UPF0176 family
PCC6301pg_0642	COG1420	regulation of RNA biosynthetic process
PCC6301pg_0644	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PCC6301pg_0645	COG0586	Pfam SNARE associated Golgi protein
PCC6301pg_0648	COG4178	(ABC) transporter
PCC6301pg_0649	COG0492	ferredoxin-NADP+ reductase activity
PCC6301pg_0651	COG3854	ATPases associated with a variety of cellular activities
PCC6301pg_0652	COG0129	dihydroxy-acid dehydratase activity
PCC6301pg_0655	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PCC6301pg_0658	COG0222	ribosome binding
PCC6301pg_0659	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PCC6301pg_0661	COG0081	regulation of translation
PCC6301pg_0662	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PCC6301pg_0663	COG0250	Participates in transcription elongation, termination and antitermination
PCC6301pg_0664	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PCC6301pg_0665	COG0542	response to heat
PCC6301pg_0666	COG0346	lactoylglutathione lyase activity
PCC6301pg_0667	COG0148	phosphopyruvate hydratase activity
PCC6301pg_0668	COG1132	(ABC) transporter
PCC6301pg_0669	COG1053	succinate dehydrogenase
PCC6301pg_0670	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PCC6301pg_0672	COG2205	protein histidine kinase activity
PCC6301pg_0672	COG2202	Pas domain
PCC6301pg_0673	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PCC6301pg_0675	COG1376	ErfK ybiS ycfS ynhG family protein
PCC6301pg_0677	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PCC6301pg_0679	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PCC6301pg_0681	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PCC6301pg_0688	COG0287	Prephenate dehydrogenase
PCC6301pg_0692	COG3264	Mechanosensitive ion channel
PCC6301pg_0692	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PCC6301pg_0693	COG1402	creatininase
PCC6301pg_0696	COG2094	Belongs to the DNA glycosylase MPG family
PCC6301pg_0697	COG0540	Belongs to the ATCase OTCase family
PCC6301pg_0699	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PCC6301pg_0701	COG0408	coproporphyrinogen oxidase activity
PCC6301pg_0707	COG0724	RNA recognition motif
PCC6301pg_0709	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PCC6301pg_0711	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PCC6301pg_0712	COG1028	Short-chain dehydrogenase reductase Sdr
PCC6301pg_0713	COG0459	protein refolding
PCC6301pg_0715	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
PCC6301pg_0717	COG0640	Transcriptional regulator
PCC6301pg_0719	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PCC6301pg_0723	COG0539	negative regulation of cytoplasmic translation
PCC6301pg_0724	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PCC6301pg_0729	COG0589	response to stress
PCC6301pg_0730	COG0824	Thioesterase
PCC6301pg_0732	COG0758	DNA mediated transformation
PCC6301pg_0732	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PCC6301pg_0736	COG1982	Orn Lys Arg decarboxylase major
PCC6301pg_0737	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PCC6301pg_0740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PCC6301pg_0741	COG0793	Belongs to the peptidase S41A family
PCC6301pg_0742	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PCC6301pg_0745	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PCC6301pg_0747	COG0582	viral genome integration into host DNA
PCC6301pg_0756	COG1061	Type III restriction enzyme res subunit
PCC6301pg_0807	COG2319	Wd-40 repeat
PCC6301pg_0808	COG0737	Belongs to the 5'-nucleotidase family
PCC6301pg_0811	COG0454	-acetyltransferase
PCC6301pg_0814	COG0142	geranyltranstransferase activity
PCC6301pg_0815	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PCC6301pg_0817	COG1480	7TM receptor with intracellular HD hydrolase
PCC6301pg_0818	COG1357	PFAM Pentapeptide repeats (8 copies)
PCC6301pg_0818	COG0515	serine threonine protein kinase
PCC6301pg_0819	COG0574	Belongs to the PEP-utilizing enzyme family
PCC6301pg_0819	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PCC6301pg_0820	COG1132	(ABC) transporter
PCC6301pg_0821	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PCC6301pg_0826	COG0625	glutathione transferase activity
PCC6301pg_0829	COG0617	tRNA 3'-terminal CCA addition
PCC6301pg_0832	COG1842	Phage shock protein A
PCC6301pg_0836	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PCC6301pg_0839	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PCC6301pg_0842	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PCC6301pg_0844	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PCC6301pg_0846	COG0438	transferase activity, transferring glycosyl groups
PCC6301pg_0850	COG0484	heat shock protein binding
PCC6301pg_0851	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PCC6301pg_0852	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PCC6301pg_0854	COG3300	MHYT domain
PCC6301pg_0854	COG5001	Diguanylate cyclase
PCC6301pg_0855	COG0735	belongs to the Fur family
PCC6301pg_0856	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PCC6301pg_0857	COG0047	phosphoribosylformylglycinamidine synthase activity
PCC6301pg_0859	COG4166	transmembrane transport
PCC6301pg_0860	COG0601	transmembrane transport
PCC6301pg_0861	COG0628	permease
PCC6301pg_0862	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PCC6301pg_0862	COG0392	lysyltransferase activity
PCC6301pg_0868	COG0017	Asparaginyl-tRNA synthetase
PCC6301pg_0875	COG2255	four-way junction helicase activity
PCC6301pg_0876	COG2144	transferase activity, transferring acyl groups
PCC6301pg_0881	COG2072	flavoprotein involved in K transport
PCC6301pg_0882	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PCC6301pg_0886	COG2805	Type II/IV secretion system protein
PCC6301pg_0887	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PCC6301pg_0889	COG1981	membrane
PCC6301pg_0891	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PCC6301pg_0893	COG0436	Aminotransferase
PCC6301pg_0896	COG0784	Response regulator, receiver
PCC6301pg_0899	COG2203	Gaf domain
PCC6301pg_0899	COG0840	transmembrane signaling receptor activity
PCC6301pg_0900	COG2198	Histidine kinase
PCC6301pg_0900	COG0784	Response regulator, receiver
PCC6301pg_0900	COG0643	Histidine kinase
PCC6301pg_0902	COG0300	oxidoreductase activity
PCC6301pg_0902	COG3000	fatty acid hydroxylase
PCC6301pg_0904	COG0857	belongs to the CobB CobQ family
PCC6301pg_0906	COG1666	GTP binding
PCC6301pg_0909	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PCC6301pg_0915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PCC6301pg_0917	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PCC6301pg_0918	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PCC6301pg_0920	COG1530	ribonuclease E activity
PCC6301pg_0921	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PCC6301pg_0923	COG0077	Prephenate dehydratase
PCC6301pg_0925	COG0051	transcription antitermination factor activity, RNA binding
PCC6301pg_0926	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PCC6301pg_0927	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PCC6301pg_0928	COG0049	tRNA binding
PCC6301pg_0929	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PCC6301pg_0932	COG0070	glutamate synthase
PCC6301pg_0932	COG0067	glutamate synthase
PCC6301pg_0932	COG0069	glutamate synthase activity
PCC6301pg_0934	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
PCC6301pg_0936	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PCC6301pg_0938	COG2894	cell division
PCC6301pg_0939	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
PCC6301pg_0940	COG3411	Ferredoxin
PCC6301pg_0946	COG1049	propionate catabolic process, 2-methylcitrate cycle
PCC6301pg_0952	COG0316	Belongs to the HesB IscA family
PCC6301pg_0955	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PCC6301pg_0958	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PCC6301pg_0962	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PCC6301pg_0963	COG1022	Amp-dependent synthetase and ligase
PCC6301pg_0967	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PCC6301pg_0968	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PCC6301pg_0969	COG5002	protein histidine kinase activity
PCC6301pg_0970	COG0151	Belongs to the GarS family
PCC6301pg_0972	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PCC6301pg_0973	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PCC6301pg_0974	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PCC6301pg_0975	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PCC6301pg_0976	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PCC6301pg_0977	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PCC6301pg_0979	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PCC6301pg_0981	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PCC6301pg_0982	COG3453	Protein conserved in bacteria
PCC6301pg_0982	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PCC6301pg_0984	COG0529	Catalyzes the synthesis of activated sulfate
PCC6301pg_0986	COG0488	(ABC) transporter
PCC6301pg_0987	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PCC6301pg_0988	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PCC6301pg_0989	COG0285	dihydrofolate synthase activity
PCC6301pg_0991	COG1231	oxidoreductase activity
PCC6301pg_0992	COG3842	ATPase activity
PCC6301pg_0995	COG1653	transport
PCC6301pg_0996	COG0157	Belongs to the NadC ModD family
PCC6301pg_0999	COG0354	folic acid binding
PCC6301pg_1001	COG0523	cobalamin synthesis protein
PCC6301pg_1003	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PCC6301pg_1004	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PCC6301pg_1005	COG3842	ATPase activity
PCC6301pg_1006	COG1316	TRANSCRIPTIONal
PCC6301pg_1007	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PCC6301pg_1007	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PCC6301pg_1010	COG0483	inositol monophosphate 1-phosphatase activity
PCC6301pg_1012	COG0181	hydroxymethylbilane synthase activity
PCC6301pg_1014	COG0412	Dienelactone hydrolase
PCC6301pg_1017	COG0251	oxidation-reduction process
PCC6301pg_1018	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PCC6301pg_1019	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PCC6301pg_1020	COG0275	rRNA processing
PCC6301pg_1021	COG0517	IMP dehydrogenase activity
PCC6301pg_1021	COG0617	tRNA 3'-terminal CCA addition
PCC6301pg_1021	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PCC6301pg_1022	COG0572	uridine kinase
PCC6301pg_1023	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PCC6301pg_1026	COG1280	lysine exporter protein (LysE YggA)
PCC6301pg_1030	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PCC6301pg_1031	COG1381	Involved in DNA repair and RecF pathway recombination
PCC6301pg_1032	COG2814	Major facilitator Superfamily
PCC6301pg_1034	COG0735	belongs to the Fur family
PCC6301pg_1040	COG1160	GTP binding
PCC6301pg_1043	COG0572	uridine kinase
PCC6301pg_1044	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PCC6301pg_1045	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PCC6301pg_1050	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PCC6301pg_1052	COG1011	Hydrolase
PCC6301pg_1055	COG0114	fumarate hydratase activity
PCC6301pg_1056	COG0788	formyltetrahydrofolate deformylase activity
PCC6301pg_1058	COG1187	pseudouridine synthase activity
PCC6301pg_1059	COG5002	protein histidine kinase activity
PCC6301pg_1060	COG0745	RESPONSE REGULATOR receiver
PCC6301pg_1064	COG0840	transmembrane signaling receptor activity
PCC6301pg_1067	COG0217	transcriptional regulatory protein
PCC6301pg_1069	COG1640	4-alpha-glucanotransferase
PCC6301pg_1070	COG4948	Mandelate Racemase Muconate Lactonizing
PCC6301pg_1071	COG0318	PFAM AMP-dependent synthetase and ligase
PCC6301pg_1075	COG0464	growth
PCC6301pg_1076	COG1293	RNA-binding protein homologous to eukaryotic snRNP
PCC6301pg_1077	COG2052	Domain of unknown function (DUF370)
PCC6301pg_1078	COG0596	Alpha beta hydrolase
PCC6301pg_1079	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PCC6301pg_1080	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PCC6301pg_1082	COG2308	Evidence 4 Homologs of previously reported genes of
PCC6301pg_1087	COG1166	arginine decarboxylase activity
PCC6301pg_1093	COG0170	dolichyl monophosphate biosynthetic process
PCC6301pg_1095	COG2385	sporulation resulting in formation of a cellular spore
PCC6301pg_1099	COG0237	dephospho-CoA kinase activity
PCC6301pg_1100	COG0237	dephospho-CoA kinase activity
PCC6301pg_1101	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PCC6301pg_1104	COG1413	lyase activity
PCC6301pg_1105	COG1413	lyase activity
PCC6301pg_1107	COG0352	thiamine-phosphate diphosphorylase activity
PCC6301pg_1110	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
PCC6301pg_1119	COG0508	dehydrogenase complex catalyzes the overall conversion of
PCC6301pg_1124	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PCC6301pg_1130	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PCC6301pg_1132	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PCC6301pg_1133	COG0569	domain protein
PCC6301pg_1134	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PCC6301pg_1135	COG1215	transferase activity, transferring glycosyl groups
PCC6301pg_1137	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PCC6301pg_1138	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PCC6301pg_1140	COG3794	PFAM blue (type 1) copper domain protein
PCC6301pg_1141	COG0542	response to heat
PCC6301pg_1145	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PCC6301pg_1148	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PCC6301pg_1150	COG4399	Belongs to the UPF0754 family
PCC6301pg_1151	COG2226	methyltransferase
PCC6301pg_1152	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PCC6301pg_1153	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PCC6301pg_1155	COG0363	glucosamine-6-phosphate deaminase activity
PCC6301pg_1156	COG0772	Belongs to the SEDS family
PCC6301pg_1157	COG0489	protein tyrosine kinase activity
PCC6301pg_1160	COG0776	regulation of translation
PCC6301pg_1161	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PCC6301pg_1163	COG0515	serine threonine protein kinase
PCC6301pg_1163	COG3064	Membrane
PCC6301pg_1163	COG4991	sh3 domain protein
PCC6301pg_1164	COG0564	pseudouridine synthase activity
PCC6301pg_1165	COG0628	permease
PCC6301pg_1167	COG0589	response to stress
PCC6301pg_1168	COG0126	phosphoglycerate kinase activity
PCC6301pg_1170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PCC6301pg_1171	COG0398	Pfam SNARE associated Golgi protein
PCC6301pg_1172	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PCC6301pg_1173	COG0515	serine threonine protein kinase
PCC6301pg_1173	COG3266	domain, Protein
PCC6301pg_1174	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PCC6301pg_1175	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PCC6301pg_1176	COG0557	exoribonuclease II activity
PCC6301pg_1177	COG0643	Histidine kinase
PCC6301pg_1177	COG2198	Histidine kinase
PCC6301pg_1179	COG0312	modulator of DNA gyrase
PCC6301pg_1184	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PCC6301pg_1193	COG0037	tRNA processing
PCC6301pg_1197	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PCC6301pg_1201	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PCC6301pg_1202	COG0271	Belongs to the BolA IbaG family
PCC6301pg_1205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PCC6301pg_1208	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PCC6301pg_1208	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PCC6301pg_1209	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PCC6301pg_1210	COG1160	GTP binding
PCC6301pg_1211	COG1116	anion transmembrane transporter activity
PCC6301pg_1214	COG1074	ATP-dependent DNA helicase activity
PCC6301pg_1215	COG5001	Diguanylate cyclase
PCC6301pg_1226	COG1691	(AIR) carboxylase
PCC6301pg_1228	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PCC6301pg_1229	COG3046	protein related to deoxyribodipyrimidine photolyase
PCC6301pg_1230	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PCC6301pg_1236	COG4447	cellulose binding
PCC6301pg_1237	COG1773	rubredoxin
PCC6301pg_1238	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PCC6301pg_1239	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PCC6301pg_1240	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PCC6301pg_1247	COG0746	molybdenum cofactor guanylyltransferase activity
PCC6301pg_1248	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PCC6301pg_1249	COG0194	GDP metabolic process
PCC6301pg_1252	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PCC6301pg_1255	COG0134	indole-3-glycerol-phosphate synthase activity
PCC6301pg_1256	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PCC6301pg_1257	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PCC6301pg_1259	COG1216	Glycosyl transferase, family 2
PCC6301pg_1263	COG4974	Belongs to the 'phage' integrase family
PCC6301pg_1265	COG4115	mRNA cleavage
PCC6301pg_1273	COG0386	Belongs to the glutathione peroxidase family
PCC6301pg_1275	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
PCC6301pg_1276	COG4251	negative regulation of phosphorylation
PCC6301pg_1278	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PCC6301pg_1279	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PCC6301pg_1281	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PCC6301pg_1283	COG1566	PFAM secretion protein HlyD family protein
PCC6301pg_1285	COG0612	Peptidase, M16
PCC6301pg_1287	COG2003	Belongs to the UPF0758 family
PCC6301pg_1289	COG2875	Belongs to the precorrin methyltransferase family
PCC6301pg_1290	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PCC6301pg_1291	COG0739	heme binding
PCC6301pg_1292	COG0723	plastoquinol--plastocyanin reductase activity
PCC6301pg_1296	COG0243	molybdopterin cofactor binding
PCC6301pg_1297	COG1116	anion transmembrane transporter activity
PCC6301pg_1298	COG1116	anion transmembrane transporter activity
PCC6301pg_1298	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PCC6301pg_1299	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PCC6301pg_1300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PCC6301pg_1301	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PCC6301pg_1303	COG0583	DNA-binding transcription factor activity
PCC6301pg_1312	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PCC6301pg_1313	COG0420	3'-5' exonuclease activity
PCC6301pg_1316	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PCC6301pg_1317	COG0625	glutathione transferase activity
PCC6301pg_1318	COG0038	chloride channel
PCC6301pg_1320	COG0003	Pfam Anion-transporting ATPase
PCC6301pg_1321	COG0501	Belongs to the peptidase M48B family
PCC6301pg_1322	COG0149	triose-phosphate isomerase activity
PCC6301pg_1323	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
PCC6301pg_1324	COG0116	Belongs to the methyltransferase superfamily
PCC6301pg_1325	COG0025	NhaP-type Na H and K H
PCC6301pg_1327	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PCC6301pg_1329	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PCC6301pg_1330	COG2239	Acts as a magnesium transporter
PCC6301pg_1331	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PCC6301pg_1334	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PCC6301pg_1334	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PCC6301pg_1337	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCC6301pg_1338	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PCC6301pg_1339	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PCC6301pg_1343	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PCC6301pg_1344	COG0314	molybdopterin synthase activity
PCC6301pg_1346	COG0315	cyclic pyranopterin monophosphate synthase activity
PCC6301pg_1346	COG0521	Mo-molybdopterin cofactor biosynthetic process
PCC6301pg_1347	COG0303	'Molybdopterin
PCC6301pg_1350	COG0312	modulator of DNA gyrase
PCC6301pg_1352	COG0640	Transcriptional regulator
PCC6301pg_1353	COG0358	DNA primase activity
PCC6301pg_1354	COG0072	phenylalanine-tRNA ligase activity
PCC6301pg_1355	COG0515	serine threonine protein kinase
PCC6301pg_1355	COG1357	PFAM Pentapeptide repeats (8 copies)
PCC6301pg_1359	COG3706	GGDEF domain
PCC6301pg_1360	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
PCC6301pg_1361	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PCC6301pg_1362	COG0514	ATP-dependent DNA helicase (RecQ)
PCC6301pg_1363	COG0589	response to stress
PCC6301pg_1369	COG0180	Tryptophanyl-tRNA synthetase
PCC6301pg_1370	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PCC6301pg_1370	COG0646	methionine synthase
PCC6301pg_1371	COG0583	DNA-binding transcription factor activity
PCC6301pg_1373	COG1132	(ABC) transporter
PCC6301pg_1374	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PCC6301pg_1375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PCC6301pg_1376	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PCC6301pg_1377	COG0803	Belongs to the bacterial solute-binding protein 9 family
PCC6301pg_1378	COG1121	(ABC) transporter
PCC6301pg_1379	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PCC6301pg_1380	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PCC6301pg_1384	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PCC6301pg_1385	COG4581	dead DEAH box helicase
PCC6301pg_1386	COG1372	Participates in initiation and elongation during chromosome replication
PCC6301pg_1386	COG0305	Participates in initiation and elongation during chromosome replication
PCC6301pg_1386	COG1372	Participates in initiation and elongation during chromosome replication
PCC6301pg_1386	COG0305	Participates in initiation and elongation during chromosome replication
PCC6301pg_1387	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PCC6301pg_1391	COG2226	methyltransferase
PCC6301pg_1393	COG0602	queuosine metabolic process
PCC6301pg_1394	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PCC6301pg_1401	COG0242	peptide deformylase activity
PCC6301pg_1402	COG0628	permease
PCC6301pg_1404	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
PCC6301pg_1405	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PCC6301pg_1406	COG0839	Belongs to the complex I subunit 6 family
PCC6301pg_1407	COG0713	ATP synthesis coupled electron transport
PCC6301pg_1408	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PCC6301pg_1412	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PCC6301pg_1413	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PCC6301pg_1415	COG2814	Major facilitator Superfamily
PCC6301pg_1417	COG0784	Response regulator, receiver
PCC6301pg_1418	COG4251	negative regulation of phosphorylation
PCC6301pg_1419	COG4279	zinc finger
PCC6301pg_1421	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
PCC6301pg_1422	COG1316	TRANSCRIPTIONal
PCC6301pg_1423	COG1357	PFAM Pentapeptide repeats (8 copies)
PCC6301pg_1427	COG2095	MarC family integral membrane protein
PCC6301pg_1428	COG1575	Belongs to the MenA family. Type 1 subfamily
PCC6301pg_1429	COG2124	cytochrome p450
PCC6301pg_1431	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PCC6301pg_1433	COG0598	Magnesium transport protein CorA
PCC6301pg_1434	COG1410	methionine synthase
PCC6301pg_1434	COG0646	methionine synthase
PCC6301pg_1437	COG0564	pseudouridine synthase activity
PCC6301pg_1440	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PCC6301pg_1441	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PCC6301pg_1443	COG0439	Biotin carboxylase
PCC6301pg_1445	COG0488	(ABC) transporter
PCC6301pg_1447	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PCC6301pg_1450	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
PCC6301pg_1451	COG1606	tRNA processing
PCC6301pg_1452	COG3338	carbonate dehydratase activity
PCC6301pg_1454	COG0537	adenosine 5'-monophosphoramidase activity
PCC6301pg_1456	COG0737	Belongs to the 5'-nucleotidase family
PCC6301pg_1457	COG0123	including yeast histone deacetylase and acetoin utilization protein
PCC6301pg_1464	COG3507	Belongs to the glycosyl hydrolase 43 family
PCC6301pg_1464	COG3693	PFAM glycoside hydrolase, family 10
PCC6301pg_1464	COG2382	esterase
PCC6301pg_1467	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PCC6301pg_1468	COG0745	RESPONSE REGULATOR receiver
PCC6301pg_1470	COG3842	ATPase activity
PCC6301pg_1471	COG1178	ABC-type Fe3 transport system permease component
PCC6301pg_1472	COG4106	trans-aconitate 2-methyltransferase activity
PCC6301pg_1473	COG1840	ABC-type Fe3 transport system, periplasmic component
PCC6301pg_1474	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PCC6301pg_1475	COG0095	Lipoate-protein ligase
PCC6301pg_1477	COG0730	response to heat
PCC6301pg_1478	COG1136	(ABC) transporter
PCC6301pg_1479	COG1007	ATP synthesis coupled electron transport
PCC6301pg_1480	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PCC6301pg_1483	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
PCC6301pg_1484	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
PCC6301pg_1485	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
PCC6301pg_1486	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
PCC6301pg_1487	COG4451	ribulose bisphosphate carboxylase, small
PCC6301pg_1487	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PCC6301pg_1488	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PCC6301pg_1489	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
PCC6301pg_1490	COG1850	ribulose-bisphosphate carboxylase activity
PCC6301pg_1491	COG4451	ribulose bisphosphate carboxylase, small
PCC6301pg_1492	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PCC6301pg_1496	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PCC6301pg_1497	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PCC6301pg_1497	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PCC6301pg_1498	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PCC6301pg_1500	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PCC6301pg_1504	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PCC6301pg_1505	COG0083	homoserine kinase activity
PCC6301pg_1506	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
PCC6301pg_1509	COG0191	fructose-bisphosphate aldolase activity
PCC6301pg_1513	COG0288	reversible hydration of carbon dioxide
PCC6301pg_1514	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PCC6301pg_1515	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PCC6301pg_1516	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PCC6301pg_1518	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PCC6301pg_1519	COG0745	RESPONSE REGULATOR receiver
PCC6301pg_1520	COG0416	fatty acid biosynthetic process
PCC6301pg_1521	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PCC6301pg_1522	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PCC6301pg_1525	COG1214	PFAM Peptidase M22, glycoprotease
PCC6301pg_1528	COG3487	Iron-regulated protein
PCC6301pg_1529	COG3659	wide pore channel activity
PCC6301pg_1534	COG2010	Cytochrome c
PCC6301pg_1542	COG0826	peptidase U32
PCC6301pg_1543	COG1032	radical SAM domain protein
PCC6301pg_1544	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PCC6301pg_1547	COG0706	membrane insertase activity
PCC6301pg_1549	COG0594	ribonuclease P activity
PCC6301pg_1550	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PCC6301pg_1555	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PCC6301pg_1556	COG0662	Cupin 2, conserved barrel domain protein
PCC6301pg_1556	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
PCC6301pg_1557	COG3659	wide pore channel activity
PCC6301pg_1558	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
PCC6301pg_1562	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
PCC6301pg_1565	COG2385	sporulation resulting in formation of a cellular spore
PCC6301pg_1566	COG0384	phenazine biosynthesis protein PhzF
PCC6301pg_1567	COG0302	gtp cyclohydrolase
PCC6301pg_1568	COG0300	oxidoreductase activity
PCC6301pg_1569	COG0825	malonyl-CoA metabolic process
PCC6301pg_1570	COG5322	oxidoreductase activity
PCC6301pg_1571	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
PCC6301pg_1573	COG0539	negative regulation of cytoplasmic translation
PCC6301pg_1576	COG0038	chloride channel
PCC6301pg_1578	COG5002	protein histidine kinase activity
PCC6301pg_1581	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PCC6301pg_1583	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PCC6301pg_1587	COG0805	protein transport
PCC6301pg_1588	COG0018	arginyl-trna synthetase
PCC6301pg_1589	COG0038	chloride channel
PCC6301pg_1595	COG2217	Heavy metal translocating P-type atpase
PCC6301pg_1599	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PCC6301pg_1606	COG1397	ADP-ribosylglycohydrolase
PCC6301pg_1609	COG0110	maltose O-acetyltransferase activity
PCC6301pg_1612	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PCC6301pg_1615	COG0740	serine-type endopeptidase activity
PCC6301pg_1616	COG0613	PHP domain protein
PCC6301pg_1617	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PCC6301pg_1619	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PCC6301pg_1620	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PCC6301pg_1623	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
PCC6301pg_1624	COG1487	ribonuclease activity
PCC6301pg_1628	COG0716	FMN binding
PCC6301pg_1629	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
PCC6301pg_1637	COG4149	molybdate abc transporter
PCC6301pg_1638	COG0725	ABC transporter, periplasmic molybdate-binding protein
PCC6301pg_1642	COG3604	Transcriptional regulator
PCC6301pg_1644	COG1217	gtp-binding protein TYPA
PCC6301pg_1645	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PCC6301pg_1646	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PCC6301pg_1647	COG0085	RNA polymerase activity
PCC6301pg_1648	COG0084	hydrolase, TatD family'
PCC6301pg_1649	COG0268	Binds directly to 16S ribosomal RNA
PCC6301pg_1650	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PCC6301pg_1652	COG5002	protein histidine kinase activity
PCC6301pg_1655	COG1187	pseudouridine synthase activity
PCC6301pg_1656	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PCC6301pg_1657	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
PCC6301pg_1659	COG1191	sigma factor activity
PCC6301pg_1660	COG0482	sulfurtransferase activity
PCC6301pg_1662	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PCC6301pg_1665	COG0473	3-isopropylmalate dehydrogenase activity
PCC6301pg_1669	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PCC6301pg_1670	COG2264	protein methyltransferase activity
PCC6301pg_1671	COG0633	Ferredoxin
PCC6301pg_1675	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PCC6301pg_1678	COG3956	TIGRFAM MazG family protein
PCC6301pg_1680	COG1116	anion transmembrane transporter activity
PCC6301pg_1681	COG1116	anion transmembrane transporter activity
PCC6301pg_1681	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PCC6301pg_1682	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PCC6301pg_1683	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PCC6301pg_1684	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PCC6301pg_1685	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
PCC6301pg_1687	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PCC6301pg_1690	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PCC6301pg_1691	COG0742	ribosomal rna small subunit methyltransferase
PCC6301pg_1693	COG2010	Cytochrome c
PCC6301pg_1695	COG0347	Belongs to the P(II) protein family
PCC6301pg_1697	COG1006	Multisubunit Na H antiporter MnhC subunit
PCC6301pg_1698	COG0651	ATP synthesis coupled electron transport
PCC6301pg_1704	COG0484	heat shock protein binding
PCC6301pg_1705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PCC6301pg_1706	COG1959	2 iron, 2 sulfur cluster binding
PCC6301pg_1707	COG3659	wide pore channel activity
PCC6301pg_1708	COG3659	wide pore channel activity
PCC6301pg_1709	COG2154	pterin-4-alpha-carbinolamine dehydratase
PCC6301pg_1712	COG1122	ATPase activity
PCC6301pg_1713	COG3688	RNA-binding protein containing a PIN domain
PCC6301pg_1716	COG5001	Diguanylate cyclase
PCC6301pg_1716	COG4251	negative regulation of phosphorylation
PCC6301pg_1716	COG3706	GGDEF domain
PCC6301pg_1716	COG2203	Gaf domain
PCC6301pg_1719	COG0571	ribonuclease III activity
PCC6301pg_1723	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PCC6301pg_1723	COG1773	rubredoxin
PCC6301pg_1724	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PCC6301pg_1727	COG0371	Dehydrogenase
PCC6301pg_1730	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PCC6301pg_1733	COG0778	Nitroreductase
PCC6301pg_1734	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PCC6301pg_1736	COG0215	cysteine-tRNA ligase activity
PCC6301pg_1739	COG0673	inositol 2-dehydrogenase activity
PCC6301pg_1741	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PCC6301pg_1743	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
PCC6301pg_1745	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
PCC6301pg_1751	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PCC6301pg_1751	COG2022	thiamine diphosphate biosynthetic process
PCC6301pg_1754	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
PCC6301pg_1755	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PCC6301pg_1756	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
PCC6301pg_1757	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PCC6301pg_1758	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PCC6301pg_1759	COG4208	sulfate ABC transporter
PCC6301pg_1760	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PCC6301pg_1762	COG4208	sulfate ABC transporter
PCC6301pg_1763	COG2897	thiosulfate sulfurtransferase activity
PCC6301pg_1766	COG1715	Restriction endonuclease
PCC6301pg_1768	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PCC6301pg_1770	COG1741	Belongs to the pirin family
PCC6301pg_1772	COG1733	regulation of RNA biosynthetic process
PCC6301pg_1773	COG0534	Mate efflux family protein
PCC6301pg_1774	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PCC6301pg_1778	COG0383	alpha-mannosidase activity
PCC6301pg_1783	COG0339	signal peptide processing
PCC6301pg_1789	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PCC6301pg_1790	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PCC6301pg_1792	COG0247	lactate metabolic process
PCC6301pg_1793	COG0277	FAD linked oxidase domain protein
PCC6301pg_1794	COG0538	isocitrate dehydrogenase activity
PCC6301pg_1798	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PCC6301pg_1801	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PCC6301pg_1802	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PCC6301pg_1805	COG2205	protein histidine kinase activity
PCC6301pg_1807	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
PCC6301pg_1810	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
PCC6301pg_1811	COG0719	Fe-S assembly protein
PCC6301pg_1812	COG0396	ATPase activity
PCC6301pg_1813	COG0719	Fe-S assembly protein
PCC6301pg_1814	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PCC6301pg_1816	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PCC6301pg_1817	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PCC6301pg_1818	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PCC6301pg_1819	COG0649	NAD binding
PCC6301pg_1820	COG0824	Thioesterase
PCC6301pg_1822	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PCC6301pg_1829	COG0456	acetyltransferase
PCC6301pg_1833	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PCC6301pg_1834	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PCC6301pg_1835	COG0686	Belongs to the AlaDH PNT family
PCC6301pg_1838	COG0483	inositol monophosphate 1-phosphatase activity
PCC6301pg_1842	COG1271	oxidase subunit
PCC6301pg_1846	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PCC6301pg_1847	COG0228	four-way junction DNA binding
PCC6301pg_1849	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PCC6301pg_1850	COG1702	phosphate starvation-inducible protein PhoH
PCC6301pg_1853	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PCC6301pg_1854	COG0497	DNA recombination
PCC6301pg_1855	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PCC6301pg_1856	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PCC6301pg_1857	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PCC6301pg_1858	COG1615	UPF0182 protein
PCC6301pg_1864	COG0484	heat shock protein binding
PCC6301pg_1865	COG0338	D12 class N6 adenine-specific DNA methyltransferase
PCC6301pg_1866	COG2133	pyrroloquinoline quinone binding
PCC6301pg_1867	COG0113	porphobilinogen synthase activity
PCC6301pg_1868	COG3118	belongs to the thioredoxin family
PCC6301pg_1869	COG0436	Aminotransferase
PCC6301pg_1870	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PCC6301pg_1876	COG0596	Alpha beta hydrolase
PCC6301pg_1877	COG2197	response regulator
PCC6301pg_1881	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PCC6301pg_1883	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PCC6301pg_1884	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PCC6301pg_1884	COG0426	domain, Protein
PCC6301pg_1885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PCC6301pg_1885	COG0426	domain, Protein
PCC6301pg_1886	COG3447	MASE1 domain protein
PCC6301pg_1886	COG5002	protein histidine kinase activity
PCC6301pg_1886	COG5001	Diguanylate cyclase
PCC6301pg_1889	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PCC6301pg_1890	COG0745	RESPONSE REGULATOR receiver
PCC6301pg_1894	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PCC6301pg_1895	COG0670	Belongs to the BI1 family
PCC6301pg_1899	COG0516	GMP reductase activity
PCC6301pg_1899	COG0517	IMP dehydrogenase activity
PCC6301pg_1900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PCC6301pg_1904	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PCC6301pg_1905	COG3118	belongs to the thioredoxin family
PCC6301pg_1906	COG0516	GMP reductase activity
PCC6301pg_1907	COG0525	valine-tRNA ligase activity
PCC6301pg_1908	COG1192	Involved in chromosome partitioning
PCC6301pg_1913	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
PCC6301pg_1916	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PCC6301pg_1919	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PCC6301pg_1921	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PCC6301pg_1922	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PCC6301pg_1923	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PCC6301pg_1925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PCC6301pg_1932	COG1797	cobyrinic acid a,c-diamide synthase activity
PCC6301pg_1934	COG2084	Dehydrogenase
PCC6301pg_1935	COG5398	heme oxygenase
PCC6301pg_1937	COG0745	RESPONSE REGULATOR receiver
PCC6301pg_1940	COG2890	protein-(glutamine-N5) methyltransferase activity
PCC6301pg_1941	COG0009	L-threonylcarbamoyladenylate synthase
PCC6301pg_1942	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PCC6301pg_1947	COG1566	PFAM secretion protein HlyD family protein
PCC6301pg_1949	COG5002	protein histidine kinase activity
PCC6301pg_1951	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PCC6301pg_1952	COG0312	modulator of DNA gyrase
PCC6301pg_1956	COG0714	Associated with various cellular activities
PCC6301pg_1958	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PCC6301pg_1959	COG1555	photosystem II stabilization
PCC6301pg_1960	COG0515	serine threonine protein kinase
PCC6301pg_1961	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PCC6301pg_1961	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PCC6301pg_1962	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PCC6301pg_1963	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PCC6301pg_1963	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
PCC6301pg_1966	COG1543	Belongs to the glycosyl hydrolase 57 family
PCC6301pg_1969	COG1054	Belongs to the UPF0176 family
PCC6301pg_1973	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PCC6301pg_1975	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PCC6301pg_1977	COG0717	Belongs to the dCTP deaminase family
PCC6301pg_1983	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PCC6301pg_1984	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
PCC6301pg_1987	COG0163	prenyltransferase activity
PCC6301pg_1988	COG0557	exoribonuclease II activity
PCC6301pg_1990	COG0704	Plays a role in the regulation of phosphate uptake
PCC6301pg_1995	COG0616	signal peptide processing
PCC6301pg_1996	COG0697	spore germination
PCC6301pg_1999	COG0495	leucyl-tRNA aminoacylation
PCC6301pg_2002	COG1595	DNA-templated transcription, initiation
PCC6301pg_2004	COG0739	heme binding
PCC6301pg_2006	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PCC6301pg_2008	COG1104	cysteine desulfurase activity
PCC6301pg_2012	COG1304	FMN binding
PCC6301pg_2014	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PCC6301pg_2016	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PCC6301pg_2017	COG0798	PFAM Bile acid sodium symporter
PCC6301pg_2018	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PCC6301pg_2020	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PCC6301pg_2020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PCC6301pg_2021	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PCC6301pg_2023	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PCC6301pg_2024	COG0322	excinuclease ABC activity
PCC6301pg_2034	COG0504	CTP synthase activity
PCC6301pg_2036	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PCC6301pg_2039	COG0442	prolyl-tRNA aminoacylation
PCC6301pg_2041	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PCC6301pg_2043	COG1619	proteins homologs of microcin C7 resistance protein MccF
PCC6301pg_2044	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PCC6301pg_2047	COG1968	undecaprenyl-diphosphatase activity
PCC6301pg_2050	COG1473	amidohydrolase
PCC6301pg_2052	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PCC6301pg_2055	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PCC6301pg_2056	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PCC6301pg_2057	COG3118	belongs to the thioredoxin family
PCC6301pg_2059	COG0583	DNA-binding transcription factor activity
PCC6301pg_2062	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
PCC6301pg_2062	COG0493	'glutamate synthase
PCC6301pg_2063	COG1562	ergosterol biosynthetic process
PCC6301pg_2064	COG3001	Fructosamine kinase
PCC6301pg_2065	COG0612	Peptidase, M16
PCC6301pg_2069	COG2119	membrane
PCC6301pg_2070	COG1970	mechanosensitive ion channel activity
PCC6301pg_2071	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PCC6301pg_2072	COG0235	Class ii aldolase
PCC6301pg_2073	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
PCC6301pg_2074	COG0140	phosphoribosyl-ATP diphosphatase activity
PCC6301pg_2074	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PCC6301pg_2076	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PCC6301pg_2080	COG0850	regulation of cytokinetic process
PCC6301pg_2083	COG1595	DNA-templated transcription, initiation
PCC6301pg_2086	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PCC6301pg_2087	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PCC6301pg_2087	COG0426	domain, Protein
PCC6301pg_2088	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PCC6301pg_2089	COG2010	Cytochrome c
PCC6301pg_2090	COG1234	tRNA 3'-trailer cleavage
PCC6301pg_2091	COG2385	sporulation resulting in formation of a cellular spore
PCC6301pg_2094	COG0515	serine threonine protein kinase
PCC6301pg_2100	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PCC6301pg_2102	COG0195	Participates in both transcription termination and antitermination
PCC6301pg_2103	COG0779	Required for maturation of 30S ribosomal subunits
PCC6301pg_2107	COG1215	transferase activity, transferring glycosyl groups
PCC6301pg_2108	COG0438	transferase activity, transferring glycosyl groups
PCC6301pg_2109	COG0166	Belongs to the GPI family
PCC6301pg_2110	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PCC6301pg_2114	COG1819	glycosyl
PCC6301pg_2120	COG1489	DNA binding
PCC6301pg_2121	COG0728	peptidoglycan biosynthetic process
PCC6301pg_2123	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PCC6301pg_2125	COG1196	nuclear chromosome segregation
PCC6301pg_2126	COG0509	glycine decarboxylation via glycine cleavage system
PCC6301pg_2127	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PCC6301pg_2127	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PCC6301pg_2128	COG2885	chlorophyll binding
PCC6301pg_2129	COG2885	chlorophyll binding
PCC6301pg_2132	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PCC6301pg_2135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PCC6301pg_2137	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PCC6301pg_2138	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PCC6301pg_2139	COG1799	cell septum assembly
PCC6301pg_2140	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PCC6301pg_2142	COG0644	oxidoreductase
PCC6301pg_2143	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PCC6301pg_2144	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PCC6301pg_2146	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PCC6301pg_2147	COG2081	HI0933 family
PCC6301pg_2149	COG1459	type II secretion system
PCC6301pg_2151	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PCC6301pg_2152	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PCC6301pg_2153	COG0443	Heat shock 70 kDa protein
PCC6301pg_2154	COG0484	heat shock protein binding
PCC6301pg_2156	COG1162	GTPase activity
PCC6301pg_2159	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PCC6301pg_2160	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
PCC6301pg_2162	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PCC6301pg_2163	COG2095	MarC family integral membrane protein
PCC6301pg_2164	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PCC6301pg_2167	COG0107	imidazoleglycerol-phosphate synthase activity
PCC6301pg_2169	COG4243	Vitamin k epoxide reductase
PCC6301pg_2170	COG0460	homoserine dehydrogenase
PCC6301pg_2171	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PCC6301pg_2172	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PCC6301pg_2174	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
PCC6301pg_2176	COG4251	negative regulation of phosphorylation
PCC6301pg_2176	COG5001	Diguanylate cyclase
PCC6301pg_2176	COG2203	Gaf domain
PCC6301pg_2176	COG3706	GGDEF domain
PCC6301pg_2184	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
PCC6301pg_2185	COG1116	anion transmembrane transporter activity
PCC6301pg_2186	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PCC6301pg_2187	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PCC6301pg_2189	COG1132	(ABC) transporter
PCC6301pg_2190	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PCC6301pg_2191	COG1940	carbohydrate kinase activity
PCC6301pg_2193	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PCC6301pg_2194	COG2205	protein histidine kinase activity
PCC6301pg_2198	COG0154	amidase activity
PCC6301pg_2200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PCC6301pg_2201	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PCC6301pg_2203	COG0505	Belongs to the CarA family
PCC6301pg_2204	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PCC6301pg_2205	COG0123	including yeast histone deacetylase and acetoin utilization protein
PCC6301pg_2209	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PCC6301pg_2214	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PCC6301pg_2216	COG0860	N-Acetylmuramoyl-L-alanine amidase
PCC6301pg_2218	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PCC6301pg_2219	COG1429	ligase activity, forming nitrogen-metal bonds
PCC6301pg_2222	COG0625	glutathione transferase activity
PCC6301pg_2226	COG0023	Translation Initiation Factor
PCC6301pg_2227	COG0133	tryptophan synthase activity
PCC6301pg_2230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PCC6301pg_2241	COG0174	glutamine synthetase
PCC6301pg_2244	COG2267	carboxylic ester hydrolase activity
PCC6301pg_2245	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PCC6301pg_2255	COG0735	belongs to the Fur family
PCC6301pg_2256	COG0783	Belongs to the Dps family
PCC6301pg_2259	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PCC6301pg_2260	COG1840	ABC-type Fe3 transport system, periplasmic component
PCC6301pg_2263	COG1950	PFAM Membrane protein of
PCC6301pg_2264	COG1803	Methylglyoxal synthase
PCC6301pg_2264	COG1597	lipid kinase activity
PCC6301pg_2265	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PCC6301pg_2266	COG1994	Peptidase M50
PCC6301pg_2266	COG0517	IMP dehydrogenase activity
PCC6301pg_2268	COG0328	RNA-DNA hybrid ribonuclease activity
PCC6301pg_2269	COG0121	glutamine amidotransferase
PCC6301pg_2275	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PCC6301pg_2278	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PCC6301pg_2282	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PCC6301pg_2284	COG0587	DNA-directed DNA polymerase activity
PCC6301pg_2287	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PCC6301pg_2289	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PCC6301pg_2290	COG0254	rRNA binding
PCC6301pg_2291	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PCC6301pg_2292	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PCC6301pg_2293	COG0101	tRNA pseudouridine synthase activity
PCC6301pg_2294	COG0203	ribosomal protein L17
PCC6301pg_2295	COG0202	RNA polymerase activity
PCC6301pg_2296	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PCC6301pg_2297	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PCC6301pg_2298	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PCC6301pg_2299	COG0563	adenylate kinase activity
PCC6301pg_2300	COG0201	protein transport
PCC6301pg_2301	COG0200	Binds to the 23S rRNA
PCC6301pg_2302	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PCC6301pg_2303	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PCC6301pg_2304	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PCC6301pg_2305	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PCC6301pg_2306	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PCC6301pg_2307	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PCC6301pg_2308	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PCC6301pg_2309	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PCC6301pg_2311	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PCC6301pg_2312	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PCC6301pg_2313	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PCC6301pg_2314	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PCC6301pg_2315	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PCC6301pg_2316	COG0089	rRNA binding
PCC6301pg_2317	COG0088	Forms part of the polypeptide exit tunnel
PCC6301pg_2318	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PCC6301pg_2321	COG0336	Belongs to the RNA methyltransferase TrmD family
PCC6301pg_2322	COG4172	Belongs to the ABC transporter superfamily
PCC6301pg_2324	COG0477	Major facilitator Superfamily
PCC6301pg_2326	COG0456	acetyltransferase
PCC6301pg_2329	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PCC6301pg_2331	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PCC6301pg_2334	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PCC6301pg_2336	COG0776	regulation of translation
PCC6301pg_2337	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PCC6301pg_2339	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PCC6301pg_2342	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PCC6301pg_2343	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
PCC6301pg_2348	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PCC6301pg_2349	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PCC6301pg_2354	COG0124	histidyl-tRNA synthetase
PCC6301pg_2356	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PCC6301pg_2359	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
PCC6301pg_2362	COG0494	nUDIX hydrolase
PCC6301pg_2363	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PCC6301pg_2365	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
PCC6301pg_2365	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
PCC6301pg_2370	COG0004	ammonium transporteR
PCC6301pg_2373	COG5002	protein histidine kinase activity
PCC6301pg_2374	COG1811	Na channel or pump
PCC6301pg_2375	COG2267	carboxylic ester hydrolase activity
PCC6301pg_2376	COG0371	Dehydrogenase
PCC6301pg_2379	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PCC6301pg_2380	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PCC6301pg_2381	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PCC6301pg_2388	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PCC6301pg_2389	COG0632	four-way junction helicase activity
PCC6301pg_2390	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PCC6301pg_2394	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PCC6301pg_2395	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PCC6301pg_2396	COG0745	RESPONSE REGULATOR receiver
PCC6301pg_2397	COG0484	heat shock protein binding
PCC6301pg_2399	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PCC6301pg_2400	COG0450	alkyl hydroperoxide reductase
PCC6301pg_2401	COG0076	glutamate decarboxylase activity
PCC6301pg_2404	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PCC6301pg_2405	COG0459	protein refolding
PCC6301pg_2406	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PCC6301pg_2407	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PCC6301pg_2408	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PCC6301pg_2409	COG2217	Heavy metal translocating P-type atpase
PCC6301pg_2410	COG3224	Antibiotic biosynthesis monooxygenase
PCC6301pg_2411	COG3093	addiction module antidote protein HigA
PCC6301pg_2413	COG0457	Tetratricopeptide repeat
PCC6301pg_2414	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PCC6301pg_2415	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PCC6301pg_2416	COG0189	ligase activity
PCC6301pg_2421	COG1078	dGTPase activity
PCC6301pg_2422	COG0793	Belongs to the peptidase S41A family
PCC6301pg_2423	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PCC6301pg_2424	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PCC6301pg_2425	COG3429	Glucose-6-phosphate dehydrogenase subunit
PCC6301pg_2425	COG3409	Peptidoglycan-binding domain 1 protein
PCC6301pg_2426	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PCC6301pg_2427	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PCC6301pg_2430	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PCC6301pg_2430	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PCC6301pg_2431	COG1160	GTP binding
PCC6301pg_2432	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PCC6301pg_2439	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PCC6301pg_2441	COG0009	L-threonylcarbamoyladenylate synthase
PCC6301pg_2442	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
PCC6301pg_2443	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PCC6301pg_2444	COG0321	lipoyl(octanoyl) transferase activity
PCC6301pg_2447	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PCC6301pg_2450	COG0475	glutathione-regulated potassium exporter activity
PCC6301pg_2452	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PCC6301pg_2453	COG0142	geranyltranstransferase activity
PCC6301pg_2456	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PCC6301pg_2463	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PCC6301pg_2465	COG4948	Mandelate Racemase Muconate Lactonizing
PCC6301pg_2466	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PCC6301pg_2467	COG1181	Belongs to the D-alanine--D-alanine ligase family
PCC6301pg_2470	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PCC6301pg_2471	COG0351	phosphomethylpyrimidine kinase
PCC6301pg_2474	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PCC6301pg_2475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PCC6301pg_2476	COG4956	integral membrane protein (PIN domain superfamily)
PCC6301pg_2477	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
PCC6301pg_2477	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
PCC6301pg_2477	COG1013	pyruvate-flavodoxin oxidoreductase activity
PCC6301pg_2477	COG0674	pyruvate-flavodoxin oxidoreductase activity
PCC6301pg_2478	COG0167	dihydroorotate dehydrogenase activity
PCC6301pg_2479	COG0409	Hydrogenase expression formation protein
PCC6301pg_2481	COG2140	Oxalate decarboxylase
PCC6301pg_2486	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PCC6301pg_2491	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PCC6301pg_2494	COG0071	Belongs to the small heat shock protein (HSP20) family
PCC6301pg_2495	COG2957	Belongs to the agmatine deiminase family
PCC6301pg_2497	COG1040	competence protein
PCC6301pg_2499	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PCC6301pg_2500	COG2022	thiamine diphosphate biosynthetic process
PCC6301pg_2500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PCC6301pg_2503	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PCC6301pg_2506	COG0330	HflC and HflK could
PCC6301pg_2507	COG2226	methyltransferase
PCC6301pg_2508	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PCC6301pg_2511	COG0583	DNA-binding transcription factor activity
PCC6301pg_2513	COG1045	serine acetyltransferase
PCC6301pg_2514	COG0672	)-iron permease
PCC6301pg_2516	COG0445	tRNA wobble uridine modification
PCC6301pg_2518	COG0702	epimerase
PCC6301pg_2521	COG0848	biopolymer transport protein
PCC6301pg_2522	COG0811	peptide transport
PCC6301pg_2525	COG4636	protein conserved in cyanobacteria
PCC6301pg_2526	COG2226	methyltransferase
PCC6301pg_2526	COG1073	alpha beta
PCC6301pg_2527	COG0440	acetolactate synthase activity
PCC6301pg_2529	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PCC6301pg_2530	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PCC6301pg_2534	COG1185	polyribonucleotide nucleotidyltransferase activity
PCC6301pg_2535	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PCC6301pg_2536	COG0581	inorganic phosphate transmembrane transporter activity
PCC6301pg_2537	COG0573	inorganic phosphate transmembrane transporter activity
PCC6301pg_2538	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PCC6301pg_2539	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PCC6301pg_2540	COG0024	Methionine aminopeptidase
PCC6301pg_2542	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PCC6301pg_2543	COG0450	alkyl hydroperoxide reductase
PCC6301pg_2549	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PCC6301pg_2552	COG0752	glycyl-tRNA synthetase alpha subunit
PCC6301pg_2557	COG2957	Belongs to the agmatine deiminase family
PCC6301pg_2558	COG1070	Carbohydrate kinase
PCC6301pg_2559	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PCC6301pg_2560	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
PCC6301pg_2562	COG0745	RESPONSE REGULATOR receiver
PCC6301pg_2563	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PCC6301pg_2564	COG0443	Heat shock 70 kDa protein
PCC6301pg_2567	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PCC6301pg_2568	COG0552	protein localization to endoplasmic reticulum
PCC6301pg_2569	COG2208	phosphoserine phosphatase activity
PCC6301pg_2571	COG0165	Argininosuccinate lyase
PCC6301pg_2573	COG1090	epimerase
PCC6301pg_2576	COG3751	2OG-Fe(II) oxygenase superfamily
PCC6301pg_2585	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PCC6301pg_2586	COG1372	Participates in initiation and elongation during chromosome replication
PCC6301pg_2586	COG0187	DNA topoisomerase II activity
PCC6301pg_2592	COG0105	UTP biosynthetic process
PCC6301pg_2594	COG2268	Band 7 protein
PCC6301pg_2596	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PCC6301pg_2601	COG0175	sulfate reduction
PCC6301pg_2603	COG1252	NADH dehydrogenase
PCC6301pg_2605	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PCC6301pg_2607	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PCC6301pg_2609	COG0434	BtpA family
PCC6301pg_2610	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PCC6301pg_2611	COG1074	ATP-dependent DNA helicase activity
PCC6301pg_2615	COG0297	glycogen (starch) synthase activity
PCC6301pg_2618	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PCC6301pg_2619	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PCC6301pg_2621	COG0544	peptidyl-prolyl cis-trans isomerase activity
PCC6301pg_2622	COG0740	serine-type endopeptidase activity
PCC6301pg_2623	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PCC6301pg_2624	COG2267	carboxylic ester hydrolase activity
PCC6301pg_2627	COG0052	Belongs to the universal ribosomal protein uS2 family
PCC6301pg_2628	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PCC6301pg_2631	COG5001	Diguanylate cyclase
PCC6301pg_2631	COG2203	Gaf domain
PCC6301pg_2631	COG3706	GGDEF domain
PCC6301pg_2631	COG4251	negative regulation of phosphorylation
PCC6301pg_2633	COG0484	heat shock protein binding
PCC6301pg_2634	COG0740	serine-type endopeptidase activity
PCC6301pg_2635	COG0740	serine-type endopeptidase activity
PCC6301pg_2636	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PCC6301pg_2638	COG0335	large ribosomal subunit rRNA binding
PCC6301pg_2641	COG2010	Cytochrome c
PCC6301pg_2642	COG1573	uracil-dna glycosylase
PCC6301pg_2644	COG0436	Aminotransferase
PCC6301pg_2647	COG0066	3-isopropylmalate dehydratase activity
PCC6301pg_2650	COG0298	carbon dioxide binding
PCC6301pg_2651	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
PCC6301pg_2652	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PCC6301pg_2653	COG0375	protein maturation
PCC6301pg_2655	COG3259	Nickel-dependent hydrogenase
PCC6301pg_2656	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
PCC6301pg_2658	COG1104	cysteine desulfurase activity
PCC6301pg_2659	COG0359	binds to the 23S rRNA
PCC6301pg_2662	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
PCC6301pg_2663	COG0419	ATPase involved in DNA repair
PCC6301pg_2664	COG0511	ligase activity, forming carbon-carbon bonds
PCC6301pg_2665	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PCC6301pg_2666	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PCC6301pg_2667	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PCC6301pg_2669	COG0284	orotidine-5'-phosphate decarboxylase activity
PCC6301pg_2670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PCC6301pg_2671	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PCC6301pg_2673	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PCC6301pg_2674	COG1121	(ABC) transporter
PCC6301pg_2675	COG0803	Belongs to the bacterial solute-binding protein 9 family
PCC6301pg_2682	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PCC6301pg_2684	COG0484	heat shock protein binding
PCC6301pg_2685	COG0443	Heat shock 70 kDa protein
PCC6301pg_2687	COG0633	Ferredoxin
PCC6301pg_2688	COG0483	inositol monophosphate 1-phosphatase activity
PCC6301pg_2691	COG1959	2 iron, 2 sulfur cluster binding
PCC6301pg_2694	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PCC6301pg_2695	COG2045	Belongs to the ComB family
PCC6301pg_2698	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PCC6301pg_2702	COG1253	flavin adenine dinucleotide binding
PCC6301pg_2703	COG0673	inositol 2-dehydrogenase activity
PCC6301pg_2704	COG2954	triphosphatase activity
PCC6301pg_2707	COG0109	protoheme IX farnesyltransferase activity
PCC6301pg_2708	COG1612	heme a metabolic process
PCC6301pg_2709	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PCC6301pg_2711	COG1845	cytochrome c oxidase, subunit III
PCC6301pg_2713	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PCC6301pg_2717	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PCC6301pg_2719	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PCC6301pg_2720	COG0546	phosphoglycolate phosphatase activity
PCC6301pg_B002	COG2894	cell division
PCC6301pg_B005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PCC6301pg_B006	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PCC6301pg_B007	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PCC6301pg_B008	COG1045	serine acetyltransferase
PCC6301pg_B009	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PCC6301pg_B014	COG0753	catalase activity
PCC6301pg_B015	COG1285	pathogenesis
PCC6301pg_B016	COG2059	Chromate
PCC6301pg_B022	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PCC6301pg_B022	COG1116	anion transmembrane transporter activity
PCC6301pg_B023	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PCC6301pg_B037	COG0582	viral genome integration into host DNA
PCC6301pg_B046	COG2205	protein histidine kinase activity
PCC6301pg_B047	COG0745	RESPONSE REGULATOR receiver
PCC6301pg_B052	COG0582	viral genome integration into host DNA